# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Flocculin PF00624.13 KPI34265.1 - 1.2 9.0 8.9 1.9 8.3 6.2 1.4 1 0 0 1 1 1 0 Flocculin repeat Mucin PF01456.12 KPI34266.1 - 1.8 8.3 12.3 2.4 7.9 8.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Pex14_N PF04695.8 KPI34268.1 - 0.02 14.9 0.2 0.024 14.7 0.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Fip1 PF05182.8 KPI34269.1 - 4.8e-23 80.1 1.2 1e-22 79.1 0.8 1.5 1 0 0 1 1 1 1 Fip1 motif CBM_X2 PF03442.9 KPI34271.1 - 1.1 9.1 5.0 0.38 10.6 0.5 2.0 1 1 1 2 2 2 0 Carbohydrate binding domain X2 Lactamase_B PF00753.22 KPI34273.1 - 1.4e-11 44.4 0.1 1.7e-11 44.1 0.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI34273.1 - 0.00013 21.5 0.2 0.00017 21.2 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KPI34273.1 - 0.013 15.2 0.1 0.016 14.9 0.1 1.1 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Mg_chelatase PF01078.16 KPI34274.1 - 0.004 16.3 0.0 0.0057 15.8 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KPI34274.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KPI34274.1 - 0.076 13.5 0.0 0.089 13.2 0.0 1.2 1 0 0 1 1 1 0 Miro-like protein AAA_5 PF07728.9 KPI34274.1 - 0.082 12.6 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 KPI34274.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase EAF PF09816.4 KPI34275.1 - 3.9e-13 49.3 0.0 7.5e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor CPSase_L_chain PF00289.17 KPI34276.1 - 6.8e-25 87.3 0.0 8.3e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KPI34276.1 - 8.3e-06 24.7 0.0 9.5e-06 24.5 0.0 1.0 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Carboxyl_trans PF01039.17 KPI34277.1 - 9.2e-62 208.9 0.0 9.8e-48 162.7 0.0 2.4 2 1 0 2 2 2 2 Carboxyl transferase domain BCDHK_Adom3 PF10436.4 KPI34278.1 - 7.1e-43 145.9 0.0 1.2e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KPI34278.1 - 2.3e-16 59.4 0.0 1.1e-15 57.3 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KPI34278.1 - 0.1 12.2 0.0 1.3 8.6 0.0 2.2 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1741 PF08427.5 KPI34279.1 - 4.6e-48 163.7 0.0 4.6e-44 150.6 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF1741) GCV_H PF01597.14 KPI34283.1 - 5.1e-38 129.4 0.5 6.9e-38 129.0 0.3 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 KPI34283.1 - 0.037 13.6 0.9 0.084 12.5 0.2 1.9 2 1 0 2 2 2 0 Biotin-requiring enzyme DUF793 PF05633.6 KPI34284.1 - 0.018 13.7 0.1 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF793) NPV_P10 PF05531.7 KPI34284.1 - 0.051 13.8 1.5 0.17 12.1 0.3 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2951 PF11166.3 KPI34284.1 - 0.14 12.0 0.8 0.25 11.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) CHASE3 PF05227.8 KPI34285.1 - 0.019 14.6 7.0 0.031 13.9 4.7 1.5 1 1 0 1 1 1 0 CHASE3 domain HemX PF04375.9 KPI34285.1 - 0.034 12.7 3.9 0.047 12.2 2.7 1.2 1 0 0 1 1 1 0 HemX Peptidase_C13 PF01650.13 KPI34285.1 - 0.046 13.0 0.0 0.075 12.3 0.0 1.3 1 1 0 1 1 1 0 Peptidase C13 family Herpes_UL25 PF01499.11 KPI34285.1 - 0.058 11.6 0.9 0.067 11.4 0.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family RIB43A PF05914.7 KPI34285.1 - 0.1 11.1 8.1 0.13 10.8 5.6 1.1 1 0 0 1 1 1 0 RIB43A Imm6 PF14434.1 KPI34285.1 - 0.11 12.2 0.7 3.3 7.4 0.1 2.1 2 0 0 2 2 2 0 Immunity protein Imm6 Mis12 PF05859.7 KPI34285.1 - 0.13 12.0 3.8 0.2 11.4 2.0 1.6 1 1 1 2 2 2 0 Mis12 protein Baculo_PEP_C PF04513.7 KPI34285.1 - 0.18 11.6 1.0 0.3 10.9 0.7 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sds3 PF08598.6 KPI34285.1 - 0.74 9.3 6.0 1.1 8.7 4.2 1.2 1 0 0 1 1 1 0 Sds3-like Fzo_mitofusin PF04799.8 KPI34285.1 - 1.9 7.8 5.2 12 5.1 0.3 2.1 1 1 1 2 2 2 0 fzo-like conserved region MtrG PF04210.8 KPI34285.1 - 4.3 7.0 5.6 46 3.7 0.1 3.4 1 1 3 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G Cep57_CLD_2 PF14197.1 KPI34285.1 - 5.4 7.0 11.7 37 4.3 6.6 2.9 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 ATP-synt_E_2 PF08112.6 KPI34285.1 - 6.5 6.8 8.2 0.86 9.7 0.4 3.0 2 1 2 4 4 4 0 ATP synthase epsilon subunit DnaJ PF00226.26 KPI34286.1 - 1.6e-19 69.3 0.2 3e-19 68.5 0.0 1.5 2 0 0 2 2 2 1 DnaJ domain Jnk-SapK_ap_N PF09744.4 KPI34286.1 - 0.0018 18.2 3.4 0.0027 17.7 2.3 1.3 1 1 0 1 1 1 1 JNK_SAPK-associated protein-1 EzrA PF06160.7 KPI34286.1 - 0.0026 16.0 1.3 0.0029 15.8 0.9 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA SRR PF07709.6 KPI34286.1 - 0.0062 16.4 0.1 11 6.7 0.1 3.2 3 0 0 3 3 3 0 Seven Residue Repeat DUF1978 PF09321.5 KPI34286.1 - 0.0071 15.8 1.8 0.0085 15.5 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1978) CENP-U PF13097.1 KPI34286.1 - 0.011 15.6 0.6 0.016 15.1 0.1 1.5 1 1 1 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit BLOC1_2 PF10046.4 KPI34286.1 - 0.012 15.7 4.0 0.067 13.3 2.8 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 KPI34286.1 - 0.015 15.1 0.4 0.021 14.6 0.3 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 KPI34286.1 - 0.017 14.9 2.4 0.028 14.2 1.7 1.3 1 0 0 1 1 1 0 Tropomyosin like COG5 PF10392.4 KPI34286.1 - 0.019 14.9 0.1 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Lant_dehyd_C PF04738.8 KPI34286.1 - 0.021 13.0 0.6 0.024 12.8 0.4 1.2 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus Fe-S_assembly PF04384.8 KPI34286.1 - 0.022 15.0 1.3 0.047 14.0 0.8 1.7 1 1 0 1 1 1 0 Iron-sulphur cluster assembly TBCA PF02970.11 KPI34286.1 - 0.062 13.3 1.4 0.14 12.2 0.9 1.6 1 1 0 1 1 1 0 Tubulin binding cofactor A AAA_32 PF13654.1 KPI34286.1 - 0.064 11.9 1.5 0.07 11.7 1.0 1.0 1 0 0 1 1 1 0 AAA domain EMP24_GP25L PF01105.19 KPI34286.1 - 0.089 12.5 0.5 0.1 12.2 0.4 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SlyX PF04102.7 KPI34286.1 - 0.094 13.1 2.0 0.21 11.9 1.4 1.6 1 0 0 1 1 1 0 SlyX Vac_Fusion PF02346.11 KPI34286.1 - 0.14 11.6 1.8 0.41 10.1 0.4 2.3 2 1 0 2 2 2 0 Chordopoxvirus fusion protein HSBP1 PF06825.7 KPI34286.1 - 0.16 11.5 1.7 0.42 10.2 0.2 2.1 1 1 0 2 2 2 0 Heat shock factor binding protein 1 Mst1_SARAH PF11629.3 KPI34286.1 - 0.2 11.5 2.3 0.67 9.8 1.6 2.0 1 1 0 1 1 1 0 C terminal SARAH domain of Mst1 Wbp11 PF09429.5 KPI34286.1 - 0.22 11.5 1.4 0.52 10.3 1.0 1.8 1 1 0 1 1 1 0 WW domain binding protein 11 XhlA PF10779.4 KPI34286.1 - 0.3 11.0 4.4 0.32 10.9 2.2 1.7 1 1 1 2 2 2 0 Haemolysin XhlA DASH_Dam1 PF08653.5 KPI34286.1 - 0.51 10.1 2.8 3.1 7.6 0.2 2.4 1 1 1 2 2 2 0 DASH complex subunit Dam1 Latarcin PF10279.4 KPI34286.1 - 0.61 10.3 5.6 0.74 10.0 2.8 1.9 1 1 1 2 2 2 0 Latarcin precursor SNARE PF05739.14 KPI34286.1 - 0.99 9.1 4.9 0.55 9.9 1.3 2.1 2 1 0 2 2 1 0 SNARE domain UBN2 PF14223.1 KPI34286.1 - 1.3 8.8 4.8 0.3 10.8 1.4 1.4 2 0 0 2 2 1 0 gag-polypeptide of LTR copia-type Prp19 PF08606.6 KPI34289.1 - 2.4e-30 104.0 1.5 4.7e-30 103.1 1.0 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 KPI34289.1 - 1.4e-17 62.7 3.1 6.6e-05 22.6 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KPI34289.1 - 9.3e-06 25.2 8.0 7.5e-05 22.3 2.3 2.3 1 1 1 2 2 2 2 PQQ-like domain Coatomer_WDAD PF04053.9 KPI34289.1 - 5.3e-05 22.1 0.0 8.9e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region MRP-L28 PF09812.4 KPI34290.1 - 1.7e-05 24.7 0.8 2.8e-05 23.9 0.3 1.5 1 1 1 2 2 2 1 Mitochondrial ribosomal protein L28 Clr5 PF14420.1 KPI34291.1 - 0.00068 19.4 0.2 0.0012 18.7 0.1 1.4 1 0 0 1 1 1 1 Clr5 domain RINGv PF12906.2 KPI34292.1 - 0.00036 20.5 5.0 0.00064 19.7 3.5 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 KPI34292.1 - 0.018 15.0 3.2 0.033 14.1 2.2 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KPI34292.1 - 1.3 8.7 5.5 2.6 7.6 3.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pyr_redox_3 PF13738.1 KPI34293.1 - 4.6e-19 69.2 0.0 1.6e-18 67.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI34293.1 - 6e-12 44.5 0.3 1.5e-11 43.2 0.1 1.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI34293.1 - 1.3e-08 34.6 0.6 4.6e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KPI34293.1 - 2.5e-07 30.5 0.2 0.00026 20.7 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KPI34293.1 - 4.6e-06 25.7 0.1 0.00021 20.3 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KPI34293.1 - 0.002 18.0 0.0 0.012 15.4 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI34293.1 - 0.015 14.4 0.1 0.75 8.8 0.0 2.6 3 0 0 3 3 3 0 Thi4 family DAO PF01266.19 KPI34293.1 - 0.027 13.4 1.2 0.63 8.8 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase GalKase_gal_bdg PF10509.4 KPI34294.1 - 1.2e-18 66.1 0.0 2.4e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 KPI34294.1 - 8.4e-17 61.1 0.0 2.7e-16 59.5 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 KPI34294.1 - 2.9e-14 52.8 3.5 1.7e-13 50.3 1.4 2.5 2 0 0 2 2 2 1 GHMP kinases N terminal domain ATG22 PF11700.3 KPI34295.1 - 3.2e-165 550.2 15.9 3.6e-165 550.0 11.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KPI34295.1 - 0.0036 16.0 47.1 0.04 12.6 16.2 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KPI34296.1 - 6.4e-28 97.4 37.1 6.4e-28 97.4 25.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Toxin_51 PF15531.1 KPI34297.1 - 0.036 13.8 1.4 0.08 12.7 1.0 1.5 1 0 0 1 1 1 0 Putative toxin 51 OppC_N PF12911.2 KPI34297.1 - 0.046 13.0 1.6 0.11 11.8 1.1 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Tachylectin PF14517.1 KPI34297.1 - 0.1 11.9 0.0 0.51 9.6 0.0 1.9 2 0 0 2 2 2 0 Tachylectin Suc_Fer-like PF06999.7 KPI34298.1 - 2.5e-34 119.2 0.0 4.8e-34 118.3 0.0 1.4 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Abi PF02517.11 KPI34298.1 - 1e-13 51.2 11.3 3.1e-13 49.6 7.8 1.9 1 1 0 1 1 1 1 CAAX protease self-immunity ADH_N PF08240.7 KPI34299.1 - 1.3e-13 50.6 4.7 1.7e-13 50.2 1.9 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI34299.1 - 2.8e-12 46.2 0.0 4.2e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KPI34299.1 - 1.8e-05 23.9 0.0 3.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KPI34299.1 - 0.0023 17.4 0.2 0.0048 16.4 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.1 KPI34299.1 - 0.027 15.3 0.0 0.043 14.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 KPI34299.1 - 0.034 13.9 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IGPD PF00475.13 KPI34300.1 - 5e-43 146.4 1.7 1.4e-28 99.6 0.0 2.1 1 1 1 2 2 2 2 Imidazoleglycerol-phosphate dehydratase DUF934 PF06073.7 KPI34300.1 - 0.01 15.5 0.0 0.042 13.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF934) Arena_RNA_pol PF06317.6 KPI34300.1 - 0.058 9.9 0.0 0.065 9.8 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase Lactamase_B PF00753.22 KPI34301.1 - 2.7e-07 30.4 0.9 8.2e-07 28.8 0.4 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI34301.1 - 4.9e-07 29.4 0.0 6.2e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Sugar_tr PF00083.19 KPI34302.1 - 1.4e-63 215.1 20.2 3.9e-62 210.3 14.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI34302.1 - 1.6e-13 50.0 34.7 3.5e-07 29.2 8.8 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KPI34302.1 - 0.72 9.9 10.4 4.3 7.4 0.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) DER1 PF04511.10 KPI34303.1 - 3.3e-48 163.8 8.1 3.7e-48 163.6 5.6 1.0 1 0 0 1 1 1 1 Der1-like family Histone PF00125.19 KPI34304.1 - 2e-29 101.5 0.2 2.7e-29 101.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KPI34304.1 - 5.8e-05 23.2 0.0 8.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 KPI34304.1 - 0.0065 15.7 0.4 0.0085 15.3 0.3 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 KPI34304.1 - 0.022 14.8 0.8 0.037 14.0 0.5 1.4 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2431 PF10354.4 KPI34305.1 - 6.8e-42 143.2 0.0 7.2e-26 91.1 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF2431) Trs65 PF12735.2 KPI34305.1 - 2.2 7.5 8.8 0.21 10.8 0.4 2.3 2 0 0 2 2 2 0 TRAPP trafficking subunit Trs65 RTC PF01137.16 KPI34306.1 - 4.9e-40 136.7 0.0 1.4e-39 135.2 0.0 1.6 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KPI34306.1 - 0.00064 19.6 0.6 0.0018 18.2 0.0 2.0 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain FtsX PF02687.16 KPI34307.1 - 0.0062 16.2 0.3 1.4 8.6 0.2 2.3 2 0 0 2 2 2 2 FtsX-like permease family BatD PF13584.1 KPI34307.1 - 0.022 13.3 0.2 0.03 12.9 0.1 1.2 1 0 0 1 1 1 0 Oxygen tolerance Cation_ATPase_C PF00689.16 KPI34307.1 - 0.062 12.8 1.3 0.11 12.0 0.9 1.6 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF3353 PF11833.3 KPI34307.1 - 0.37 10.2 2.9 0.76 9.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) DUF2668 PF10873.3 KPI34307.1 - 1.2 9.3 3.6 0.46 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) DUF4083 PF13314.1 KPI34307.1 - 3.2 7.6 4.8 2.2 8.1 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF3072 PF11272.3 KPI34308.1 - 2.4e-28 97.5 8.0 5.9e-16 57.8 0.8 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF3072) Terminase_2 PF03592.11 KPI34308.1 - 0.13 12.5 1.6 0.15 12.3 0.7 1.3 1 1 0 1 1 1 0 Terminase small subunit Metallophos PF00149.23 KPI34309.1 - 1.9e-13 50.2 3.2 5.2e-13 48.8 2.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KPI34309.1 - 5.5e-12 45.7 0.1 1.2e-11 44.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.17 KPI34310.1 - 2.3e-13 49.5 0.0 5.4e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI34310.1 - 8.3e-11 41.7 0.0 1.8e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI34310.1 - 1.2e-08 34.6 0.1 2.4e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPI-anchored PF10342.4 KPI34311.1 - 1.4e-19 70.3 0.2 1.4e-19 70.3 0.1 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Inhibitor_I67 PF11405.3 KPI34312.1 - 0.1 12.6 0.9 0.23 11.5 0.6 1.6 1 0 0 1 1 1 0 Bromelain inhibitor VI Fungal_trans PF04082.13 KPI34313.1 - 3.1e-20 72.1 0.0 5.8e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI34313.1 - 2e-07 30.8 16.0 3.4e-07 30.0 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CaKB PF03185.10 KPI34313.1 - 0.046 13.1 0.7 0.09 12.1 0.5 1.4 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit HalX PF08663.5 KPI34313.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 HalX domain Phage_GP20 PF06810.6 KPI34313.1 - 0.11 11.9 0.2 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 FA_hydroxylase PF04116.8 KPI34314.1 - 3e-07 30.8 21.5 3.8e-07 30.4 14.9 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 KPI34314.1 - 0.024 14.6 0.1 0.034 14.1 0.1 1.3 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region CK_II_beta PF01214.13 KPI34315.1 - 2.1e-73 245.7 0.0 4.5e-73 244.6 0.0 1.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Sporozoite_P67 PF05642.6 KPI34315.1 - 2.5 5.8 10.2 11 3.7 6.4 1.8 1 1 1 2 2 2 0 Sporozoite P67 surface antigen E1_dh PF00676.15 KPI34316.1 - 6.1e-112 373.2 0.3 7.7e-112 372.8 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KPI34316.1 - 0.00029 19.8 0.0 0.00045 19.2 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 KPI34316.1 - 0.015 14.9 0.7 0.032 13.8 0.5 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pkinase PF00069.20 KPI34317.1 - 5.4e-76 255.1 0.0 6.7e-76 254.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI34317.1 - 1.1e-36 126.1 0.0 1.6e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KPI34317.1 - 0.012 15.4 0.2 0.044 13.5 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KPI34317.1 - 0.023 13.7 0.2 0.045 12.8 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KPI34317.1 - 0.037 12.9 0.0 0.09 11.7 0.0 1.7 1 1 0 1 1 1 0 Kinase-like DUF2399 PF09664.5 KPI34317.1 - 0.083 12.7 0.0 1.9 8.3 0.0 2.7 1 1 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) Clat_adaptor_s PF01217.15 KPI34318.1 - 8.1e-09 35.3 0.0 0.0048 16.6 0.1 2.2 2 0 0 2 2 2 2 Clathrin adaptor complex small chain zf-RING_2 PF13639.1 KPI34319.1 - 3.3e-09 36.4 2.4 5.1e-09 35.8 1.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KPI34319.1 - 5.4e-06 26.4 0.8 1.3e-05 25.2 0.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KPI34319.1 - 0.00091 19.0 0.2 0.0014 18.3 0.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KPI34319.1 - 0.0054 16.7 1.2 0.0095 15.9 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1179 PF06678.6 KPI34319.1 - 0.12 12.7 0.7 0.25 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) zf-C3HC4 PF00097.20 KPI34319.1 - 0.18 11.4 1.2 0.34 10.6 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UCH_1 PF13423.1 KPI34320.1 - 1.3e-55 188.9 1.8 2e-55 188.3 1.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KPI34320.1 - 2e-18 67.2 0.0 7.9e-18 65.2 0.0 2.0 2 0 0 2 2 2 1 Exonuclease UCH PF00443.24 KPI34320.1 - 2.3e-06 26.9 0.2 6.7e-06 25.4 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MARVEL PF01284.18 KPI34321.1 - 3.3 7.5 14.5 5.2 6.8 10.0 1.3 1 0 0 1 1 1 0 Membrane-associating domain LRR_4 PF12799.2 KPI34323.1 - 0.18 11.4 0.5 0.44 10.2 0.3 1.7 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Mito_carr PF00153.22 KPI34324.1 - 1.2e-62 207.6 1.8 1e-21 76.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.17 KPI34325.1 - 0.069 12.5 0.0 0.084 12.2 0.0 1.1 1 0 0 1 1 1 0 Ras family Cpn60_TCP1 PF00118.19 KPI34326.1 - 7.8e-118 394.1 2.7 9.5e-118 393.8 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4621 PF15414.1 KPI34326.1 - 0.019 13.6 0.4 0.041 12.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4621) NST1 PF13945.1 KPI34327.1 - 1.2e-57 195.0 3.8 1.2e-57 195.0 2.6 4.6 3 1 1 4 4 4 1 Salt tolerance down-regulator Helicase_C PF00271.26 KPI34328.1 - 5.4e-27 93.4 0.0 1.1e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KPI34328.1 - 7.1e-22 77.6 0.0 1.1e-18 67.3 0.0 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase Ras PF00071.17 KPI34330.1 - 9.4e-50 168.1 0.0 1.1e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KPI34330.1 - 1.6e-16 60.8 0.0 2.3e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KPI34330.1 - 7.6e-08 31.7 0.0 1.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KPI34330.1 - 0.007 15.5 0.0 0.0075 15.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KPI34330.1 - 0.016 14.7 0.0 3.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 KPI34330.1 - 0.027 13.7 0.0 0.049 12.8 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KPI34330.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase OKR_DC_1_N PF03709.10 KPI34330.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain AAA_21 PF13304.1 KPI34330.1 - 0.15 11.9 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.19 KPI34331.1 - 4.2e-23 81.7 0.0 4.6e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NAD_binding_10 PF13460.1 KPI34333.1 - 2.6e-08 34.0 0.1 4.2e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KPI34333.1 - 1.5e-07 30.8 0.0 2.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family DUF877 PF05943.7 KPI34333.1 - 0.022 13.2 0.0 0.032 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF877) Peptidase_M14 PF00246.19 KPI34334.1 - 1.3e-66 225.1 0.0 1.7e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Aft1_HRA PF11786.3 KPI34335.1 - 1.2e-19 70.3 11.6 1.2e-19 70.3 8.0 2.8 3 0 0 3 3 3 1 Aft1 HRA domain bZIP_1 PF00170.16 KPI34335.1 - 7.7e-12 44.9 7.3 1.4e-11 44.1 5.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor Aft1_HRR PF11787.3 KPI34335.1 - 1.9e-11 44.8 11.6 1.9e-11 44.8 8.0 4.6 3 3 1 4 4 4 1 Aft1 HRR domain bZIP_2 PF07716.10 KPI34335.1 - 1.5e-06 27.8 6.4 4e-06 26.5 4.4 1.7 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.3 KPI34335.1 - 0.0001 22.7 14.4 0.0001 22.7 10.0 4.0 4 2 1 5 5 5 1 Aft1 osmotic stress response (OSM) domain bZIP_Maf PF03131.12 KPI34335.1 - 0.0022 18.2 4.8 0.0022 18.2 3.4 2.7 4 0 0 4 4 4 1 bZIP Maf transcription factor RTBV_P46 PF06216.6 KPI34335.1 - 0.094 11.5 0.1 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DivIC PF04977.10 KPI34335.1 - 0.23 10.9 1.3 0.59 9.6 0.9 1.6 1 0 0 1 1 1 0 Septum formation initiator TCTP PF00838.12 KPI34336.1 - 6.9e-44 149.7 0.3 7.8e-44 149.5 0.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein ISG65-75 PF11727.3 KPI34336.1 - 0.048 12.7 1.7 0.056 12.4 1.2 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein p450 PF00067.17 KPI34337.1 - 2.2e-23 82.5 0.0 2.5e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KPI34338.1 - 9.9e-66 222.1 0.0 1.3e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ARID PF01388.16 KPI34340.1 - 4.7e-15 55.2 0.1 1.1e-14 54.0 0.1 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain AAA PF00004.24 KPI34342.1 - 4.4e-45 153.1 0.8 1.4e-44 151.4 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KPI34342.1 - 4.2e-09 36.2 0.1 1.5e-08 34.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KPI34342.1 - 6.4e-08 32.6 0.0 1.4e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KPI34342.1 - 4.9e-07 29.9 0.0 1.4e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KPI34342.1 - 1e-06 28.9 0.7 0.00032 20.8 0.5 2.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KPI34342.1 - 4.1e-06 25.9 0.0 7.7e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KPI34342.1 - 0.00028 20.7 0.0 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KPI34342.1 - 0.00052 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KPI34342.1 - 0.00053 19.1 0.0 0.0013 17.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KPI34342.1 - 0.00093 20.0 0.0 0.005 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KPI34342.1 - 0.00094 18.8 1.0 0.056 13.0 0.0 3.1 4 1 0 4 4 3 1 NACHT domain RNA_helicase PF00910.17 KPI34342.1 - 0.0011 19.0 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 KPI34342.1 - 0.0013 17.5 0.0 0.0023 16.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 KPI34342.1 - 0.0015 18.2 0.2 0.0037 16.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 KPI34342.1 - 0.002 17.8 0.0 0.0063 16.2 0.0 1.9 2 0 0 2 2 1 1 NTPase Zeta_toxin PF06414.7 KPI34342.1 - 0.0032 16.5 0.1 0.012 14.7 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.6 KPI34342.1 - 0.0045 16.5 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KPI34342.1 - 0.0054 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KPI34342.1 - 0.0056 16.2 0.7 0.014 14.9 0.0 2.0 2 1 1 3 3 3 1 AAA domain UPF0079 PF02367.12 KPI34342.1 - 0.0056 16.2 0.0 0.047 13.3 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KPI34342.1 - 0.0061 16.9 0.2 0.85 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KPI34342.1 - 0.0061 15.7 0.2 0.016 14.3 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 KPI34342.1 - 0.0061 16.2 0.6 0.047 13.3 0.0 2.5 2 1 1 3 3 3 1 Archaeal ATPase IstB_IS21 PF01695.12 KPI34342.1 - 0.0072 15.7 0.1 0.03 13.7 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.1 KPI34342.1 - 0.013 15.1 0.1 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KPI34342.1 - 0.015 14.9 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KPI34342.1 - 0.029 14.6 0.0 0.095 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KPI34342.1 - 0.031 13.6 3.9 0.083 12.2 0.1 2.7 2 1 0 3 3 3 0 AAA domain KaiC PF06745.8 KPI34342.1 - 0.032 13.3 1.2 0.47 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC Bac_DnaA PF00308.13 KPI34342.1 - 0.034 13.7 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.21 KPI34342.1 - 0.042 13.3 0.1 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KPI34342.1 - 0.084 12.9 0.0 0.43 10.6 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain Viral_Hsp90 PF03225.9 KPI34342.1 - 0.093 11.0 0.0 0.14 10.3 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue NB-ARC PF00931.17 KPI34342.1 - 0.14 10.9 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 KPI34342.1 - 0.17 10.7 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 KPI34343.1 - 2.9e-12 46.5 0.0 6.7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 KPI34343.1 - 2.9e-07 29.6 0.0 1.1e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Phosphorylase superfamily AAA_16 PF13191.1 KPI34343.1 - 3.3e-06 27.2 0.0 5.7e-05 23.1 0.0 3.0 4 0 0 4 4 4 1 AAA ATPase domain AAA PF00004.24 KPI34343.1 - 0.00013 22.1 0.0 0.00051 20.2 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KPI34343.1 - 0.0088 15.7 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 KPI34343.1 - 0.0093 14.8 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KPI34343.1 - 0.01 15.9 0.0 0.034 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KPI34343.1 - 0.014 15.0 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 KPI34343.1 - 0.051 13.2 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 NTPase PduV-EutP PF10662.4 KPI34343.1 - 0.071 12.6 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 KPI34343.1 - 0.082 12.6 0.1 0.26 11.0 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain Bac_DnaA PF00308.13 KPI34343.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Pkinase PF00069.20 KPI34344.1 - 5.4e-09 35.5 2.1 3.5e-08 32.9 0.0 3.1 4 1 0 4 4 4 1 Protein kinase domain FA_hydroxylase PF04116.8 KPI34345.1 - 7.7e-18 64.9 13.0 7.7e-18 64.9 9.0 2.2 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Transport_MerF PF11431.3 KPI34345.1 - 0.14 11.8 0.7 0.34 10.6 0.5 1.6 1 0 0 1 1 1 0 Membrane transport protein MerF COX4 PF02936.9 KPI34346.1 - 1.3e-51 174.1 0.2 1.6e-51 173.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Tantalus PF15386.1 KPI34347.1 - 0.28 10.9 1.2 1.3 8.8 0.4 2.2 2 0 0 2 2 2 0 Drosophila Tantalus-like Daxx PF03344.10 KPI34347.1 - 1.5 7.1 5.1 2.1 6.7 3.6 1.1 1 0 0 1 1 1 0 Daxx Family GST_C_3 PF14497.1 KPI34348.1 - 0.0015 18.9 0.2 0.0023 18.3 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 KPI34348.1 - 0.0021 18.2 0.0 0.0046 17.1 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein DUF2731 PF10806.3 KPI34348.1 - 0.034 14.3 0.0 0.12 12.6 0.0 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2731) GST_C_2 PF13410.1 KPI34348.1 - 0.33 10.8 2.1 0.28 11.0 0.2 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ATP-synt_ab PF00006.20 KPI34349.1 - 3.1e-40 137.9 0.3 8.4e-37 126.7 0.2 2.6 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 KPI34349.1 - 1.4e-24 86.1 1.0 4.2e-24 84.5 0.2 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 KPI34349.1 - 1.5e-24 86.6 0.2 3.2e-24 85.5 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain AAA_25 PF13481.1 KPI34349.1 - 0.012 15.0 0.1 0.06 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KPI34349.1 - 0.012 15.5 0.4 0.35 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 KPI34349.1 - 0.015 14.4 0.1 0.027 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KaiC PF06745.8 KPI34349.1 - 0.021 13.9 0.1 0.036 13.1 0.1 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 KPI34349.1 - 0.024 14.3 0.2 0.074 12.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KPI34349.1 - 0.07 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 KPI34349.1 - 0.093 12.4 0.1 0.99 9.1 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 KPI34349.1 - 0.094 11.5 0.7 0.59 8.9 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 KPI34349.1 - 0.095 12.3 0.1 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase FAD_binding_1 PF00667.15 KPI34350.1 - 2.4e-33 115.4 0.0 3.8e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KPI34350.1 - 1.4e-21 76.9 0.2 4.7e-21 75.2 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 KPI34350.1 - 2.8e-07 31.0 0.0 1.4e-05 25.6 0.0 2.4 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KPI34350.1 - 0.00088 19.2 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_NdrI PF07972.6 KPI34350.1 - 0.014 15.3 0.0 0.039 13.8 0.0 1.7 2 0 0 2 2 2 0 NrdI Flavodoxin like FMN_red PF03358.10 KPI34350.1 - 0.086 12.3 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 NADPH-dependent FMN reductase Daxx PF03344.10 KPI34351.1 - 6.8 5.0 13.5 7.7 4.8 9.4 1.1 1 0 0 1 1 1 0 Daxx Family AMP-binding PF00501.23 KPI34352.1 - 1.6e-81 273.8 0.0 1.9e-81 273.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI34352.1 - 2.3e-11 44.4 0.5 6.1e-11 43.1 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cofilin_ADF PF00241.15 KPI34353.1 - 1.8e-22 79.5 0.1 3.1e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Utp21 PF04192.7 KPI34353.1 - 0.063 12.3 0.1 0.16 11.0 0.1 1.6 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Alpha-amylase PF00128.19 KPI34356.1 - 2.4e-88 296.5 0.3 5.1e-87 292.2 0.2 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KPI34356.1 - 0.008 15.1 0.0 0.02 13.7 0.0 1.6 2 0 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme Alpha-amylase_C PF02806.13 KPI34356.1 - 0.092 12.9 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain VTC PF09359.5 KPI34357.1 - 1.8e-88 296.2 1.0 1.8e-88 296.2 0.7 2.0 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 KPI34357.1 - 7.1e-19 68.6 13.6 2.4e-12 47.1 2.9 3.3 2 1 1 3 3 3 2 SPX domain NPV_P10 PF05531.7 KPI34357.1 - 0.0023 18.1 2.4 0.23 11.7 0.0 2.8 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Syntaxin-18_N PF10496.4 KPI34357.1 - 0.19 11.5 5.7 0.86 9.4 1.2 3.1 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF1664 PF07889.7 KPI34357.1 - 0.52 10.1 9.4 1.9 8.3 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.6 KPI34357.1 - 4.2 4.7 6.4 1.5 6.3 0.1 2.0 2 0 0 2 2 2 0 Prominin Fib_alpha PF08702.5 KPI34357.1 - 4.8 7.2 7.8 23 5.0 0.1 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.4 KPI34357.1 - 5.7 7.1 9.8 2.1 8.5 3.4 2.5 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NUDIX PF00293.23 KPI34358.1 - 2.2e-15 56.4 0.0 4.4e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NMO PF03060.10 KPI34359.1 - 2.6e-43 148.4 0.9 1.2e-33 116.6 0.4 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 KPI34359.1 - 3.3e-07 29.5 0.0 4.8e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KPI34359.1 - 9.5e-05 21.3 4.4 0.00018 20.5 2.5 1.8 1 1 1 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KPI34359.1 - 0.012 14.6 0.9 0.018 14.0 0.6 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase PcrB PF01884.12 KPI34359.1 - 0.12 11.5 0.2 0.23 10.6 0.2 1.4 1 0 0 1 1 1 0 PcrB family ThiG PF05690.9 KPI34359.1 - 0.14 11.1 0.2 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Cupin_2 PF07883.6 KPI34360.1 - 1.7e-07 30.6 0.0 2.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Cupin domain MFS_1 PF07690.11 KPI34361.1 - 1.1e-34 119.7 40.3 1.1e-34 119.7 27.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily RskA PF10099.4 KPI34361.1 - 0.049 13.3 0.4 3.4 7.3 0.3 2.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Abhydrolase_3 PF07859.8 KPI34362.1 - 1.1e-41 142.7 0.0 1.6e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI34362.1 - 0.0052 16.5 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KPI34362.1 - 0.045 13.6 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase COesterase PF00135.23 KPI34362.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Grp1_Fun34_YaaH PF01184.14 KPI34363.1 - 2.2e-25 89.2 13.6 2.9e-25 88.8 9.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family EHN PF06441.7 KPI34365.1 - 9.8e-31 105.9 0.0 1.8e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KPI34365.1 - 3.2e-09 37.0 0.1 2.2e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI34365.1 - 2.8e-07 30.3 0.0 6.9e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI34366.1 - 1e-05 25.5 0.1 1.6e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KPI34366.1 - 1.4e-05 24.8 0.0 2.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.2 KPI34366.1 - 0.00028 20.6 0.0 0.00065 19.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 KPI34366.1 - 0.00037 20.2 0.0 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) DUF1100 PF06500.6 KPI34366.1 - 0.00049 18.8 0.1 0.087 11.3 0.0 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.13 KPI34366.1 - 0.0012 18.3 0.1 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 KPI34366.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family AXE1 PF05448.7 KPI34366.1 - 0.041 12.3 0.0 0.064 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Zn_clus PF00172.13 KPI34367.1 - 6.1e-09 35.6 8.3 1.1e-08 34.7 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KPI34367.1 - 0.00016 20.6 0.0 0.00023 20.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 KPI34369.1 - 1.4e-20 74.2 0.0 3.9e-20 72.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI34369.1 - 2.8e-18 65.4 0.2 2.3e-16 59.0 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI34369.1 - 5.6e-12 45.5 0.0 1.5e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI34369.1 - 1.5e-08 33.9 0.0 2.7e-05 23.2 0.0 3.2 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KPI34369.1 - 0.00065 19.5 0.3 0.017 14.8 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KPI34369.1 - 0.011 14.8 0.1 0.048 12.7 0.0 2.0 3 0 0 3 3 3 0 Thi4 family HI0933_like PF03486.9 KPI34369.1 - 0.055 11.9 0.0 0.086 11.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 KPI34369.1 - 0.056 12.3 0.0 0.15 10.9 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Zn_clus PF00172.13 KPI34370.1 - 2.7e-06 27.1 8.3 4.7e-06 26.3 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KPI34370.1 - 2.6e-05 23.2 0.1 5.2e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF904 PF06005.7 KPI34371.1 - 0.001 19.2 2.1 0.0016 18.6 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF904) TBPIP PF07106.8 KPI34371.1 - 0.0017 17.9 1.0 0.0021 17.6 0.7 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TSC22 PF01166.13 KPI34371.1 - 0.011 15.6 2.4 0.02 14.8 1.7 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Uso1_p115_C PF04871.8 KPI34371.1 - 0.023 14.6 4.3 0.031 14.2 2.9 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region ApoO PF09769.4 KPI34371.1 - 0.023 14.3 0.9 0.033 13.9 0.6 1.1 1 0 0 1 1 1 0 Apolipoprotein O DUF972 PF06156.8 KPI34371.1 - 0.034 14.5 0.7 0.055 13.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) HALZ PF02183.13 KPI34371.1 - 0.071 12.8 1.6 0.29 10.8 0.6 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper FlxA PF14282.1 KPI34371.1 - 0.095 12.6 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 FlxA-like protein VPS28 PF03997.7 KPI34371.1 - 0.12 12.0 0.2 0.2 11.2 0.1 1.3 1 1 0 1 1 1 0 VPS28 protein Atg14 PF10186.4 KPI34371.1 - 0.12 11.2 1.1 0.16 10.8 0.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 KPI34371.1 - 0.13 12.3 4.3 0.21 11.6 1.8 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 KPI34371.1 - 0.13 11.9 1.7 0.16 11.6 1.2 1.2 1 0 0 1 1 1 0 Mnd1 family VSG_B PF13206.1 KPI34371.1 - 0.15 11.2 3.6 0.18 10.9 2.5 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain Bap31 PF05529.7 KPI34371.1 - 0.19 11.1 2.3 0.29 10.5 1.6 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF2562 PF10814.3 KPI34371.1 - 0.8 9.6 5.2 0.21 11.5 1.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2562) CP12 PF02672.10 KPI34371.1 - 2.4 8.6 7.2 5.5 7.5 0.1 2.9 1 1 1 2 2 2 0 CP12 domain LPP PF04728.8 KPI34371.1 - 4 7.3 7.3 0.73 9.6 0.1 3.1 3 1 0 3 3 3 0 Lipoprotein leucine-zipper ADH_N PF08240.7 KPI34372.1 - 1.2e-12 47.5 0.8 1.9e-10 40.4 0.2 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI34372.1 - 1.2e-09 37.7 0.0 2.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI34372.1 - 6.9e-05 23.7 0.1 0.00015 22.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Nup54 PF13874.1 KPI34373.1 - 0.017 14.8 4.5 0.072 12.7 2.9 2.3 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 COesterase PF00135.23 KPI34374.1 - 2.5e-64 217.9 0.0 3.6e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI34374.1 - 0.00051 19.6 0.1 0.21 11.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI34374.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Epimerase PF01370.16 KPI34375.1 - 4.9e-11 42.5 0.0 1.7e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI34375.1 - 0.00011 21.0 0.0 0.0018 17.0 0.0 2.0 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KPI34375.1 - 0.00013 20.9 0.0 0.00082 18.3 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 KPI34375.1 - 0.27 11.1 1.6 1.3 8.9 0.0 2.6 3 0 0 3 3 3 0 short chain dehydrogenase adh_short PF00106.20 KPI34376.1 - 7.1e-14 52.0 2.2 1.2e-13 51.3 1.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI34376.1 - 2.4e-09 37.3 2.5 4.3e-09 36.4 1.7 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KPI34376.1 - 0.024 14.6 0.1 0.046 13.7 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding DUF1776 PF08643.5 KPI34376.1 - 0.044 12.9 0.0 0.088 11.9 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) KR PF08659.5 KPI34376.1 - 0.12 11.9 1.1 0.22 11.1 0.8 1.3 1 0 0 1 1 1 0 KR domain Fungal_trans_2 PF11951.3 KPI34378.1 - 0.029 13.0 0.1 0.53 8.8 0.0 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain PMT PF02366.13 KPI34379.1 - 5.9e-66 222.3 9.7 5.9e-66 222.3 6.7 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KPI34379.1 - 1.4e-54 184.5 0.3 2.4e-54 183.7 0.2 1.4 1 0 0 1 1 1 1 MIR domain Fungal_trans PF04082.13 KPI34380.1 - 1.3e-06 27.5 0.1 2e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HIRA_B PF09453.5 KPI34382.1 - 0.41 10.2 5.8 9.7 5.8 0.5 3.4 2 0 0 2 2 2 0 HIRA B motif Nrap PF03813.9 KPI34383.1 - 2.2e-245 816.6 0.0 3.1e-245 816.1 0.0 1.0 1 0 0 1 1 1 1 Nrap protein SUR7 PF06687.7 KPI34384.1 - 1.6e-26 93.2 7.9 2e-26 92.8 5.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF485 PF04341.7 KPI34384.1 - 1.2 8.8 4.1 0.97 9.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Aldo_ket_red PF00248.16 KPI34385.1 - 5.1e-37 127.2 0.1 7.6e-29 100.4 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family MFS_1 PF07690.11 KPI34386.1 - 7.2e-30 103.8 33.7 1e-29 103.4 23.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DAD PF02109.11 KPI34386.1 - 0.23 11.5 2.7 0.59 10.2 0.0 2.9 3 0 0 3 3 3 0 DAD family GRA6 PF05084.8 KPI34386.1 - 0.26 10.7 2.7 2.9 7.3 0.4 2.2 2 0 0 2 2 2 0 Granule antigen protein (GRA6) ESSS PF10183.4 KPI34386.1 - 0.79 10.1 4.0 0.7 10.3 0.1 2.7 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PRP21_like_P PF12230.3 KPI34387.1 - 2.6e-59 200.5 7.0 1.9e-58 197.7 4.8 2.0 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 KPI34387.1 - 7.9e-36 121.5 0.4 1.8e-18 65.9 0.0 2.4 2 0 0 2 2 2 2 Surp module UPF0547 PF10571.4 KPI34387.1 - 0.049 13.3 0.2 0.082 12.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 KPI34387.1 - 0.12 11.8 0.4 0.23 11.0 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain FYDLN_acid PF09538.5 KPI34387.1 - 6.8 7.3 6.6 1.4 9.5 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) adh_short PF00106.20 KPI34388.1 - 1.1e-14 54.7 0.0 1.9e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI34388.1 - 2.6e-09 37.0 0.0 3.9e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 KR domain ABC1 PF03109.11 KPI34389.1 - 1.4e-22 79.8 0.1 3.2e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 KPI34389.1 - 0.0084 15.8 0.4 0.3 10.7 0.0 2.7 2 1 0 3 3 3 1 Phosphotransferase enzyme family Aminotran_3 PF00202.16 KPI34390.1 - 7.6e-44 149.9 0.1 2e-43 148.5 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KPI34390.1 - 0.001 18.2 0.1 0.0017 17.6 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KPI34392.1 - 8.2e-35 119.8 0.0 1.1e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme EB1 PF03271.12 KPI34393.1 - 5.4e-16 58.3 0.6 1.3e-15 57.1 0.4 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 KPI34393.1 - 4e-07 30.0 0.2 7.6e-07 29.1 0.2 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain COesterase PF00135.23 KPI34395.1 - 2.8e-101 339.8 0.0 3.4e-101 339.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI34395.1 - 1e-07 31.7 1.1 5e-07 29.5 0.7 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI34395.1 - 0.02 14.6 0.2 0.039 13.7 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Solute_trans_a PF03619.11 KPI34396.1 - 5.5e-26 91.4 18.0 8.9e-26 90.8 12.5 1.3 1 1 0 1 1 1 1 Organic solute transporter Ostalpha DUF2919 PF11143.3 KPI34396.1 - 0.026 14.3 1.3 0.026 14.3 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) DUF4492 PF14899.1 KPI34396.1 - 0.033 13.6 0.7 0.033 13.6 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) DUF2499 PF10693.4 KPI34396.1 - 0.13 12.3 3.0 0.13 12.2 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2499) Ni_hydr_CYTB PF01292.15 KPI34396.1 - 0.13 11.6 6.0 0.078 12.3 1.5 2.3 1 1 2 3 3 3 0 Prokaryotic cytochrome b561 BT1 PF03092.11 KPI34396.1 - 1.1 7.8 8.7 1.7 7.2 6.0 1.3 1 1 0 1 1 1 0 BT1 family Chromate_transp PF02417.10 KPI34396.1 - 1.2 8.6 13.8 0.031 13.8 1.3 2.3 2 0 0 2 2 2 0 Chromate transporter Cyto_ox_2 PF02322.10 KPI34396.1 - 3.7 6.6 15.5 0.27 10.3 1.4 2.1 2 0 0 2 2 2 0 Cytochrome oxidase subunit II Git3_C PF11970.3 KPI34396.1 - 3.8 7.3 12.3 0.58 9.9 1.6 3.0 2 1 1 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term Epimerase PF01370.16 KPI34397.1 - 1.9e-15 56.9 0.0 3e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI34397.1 - 4.7e-12 46.2 0.0 1.3e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KPI34397.1 - 1.2e-08 34.5 0.0 0.00094 18.4 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family adh_short PF00106.20 KPI34397.1 - 0.0054 16.6 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KPI34397.1 - 0.018 13.9 0.0 0.057 12.3 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.7 KPI34397.1 - 0.094 11.6 0.0 0.23 10.3 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein Ribosomal_L5_C PF00673.16 KPI34399.1 - 3.1e-27 94.1 0.0 4.6e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KPI34399.1 - 0.0025 17.5 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 DASH_Dad1 PF08649.5 KPI34400.1 - 3.7e-18 64.9 0.1 4.5e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 TRI12 PF06609.8 KPI34401.1 - 5e-55 186.8 26.4 2.2e-53 181.4 18.3 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI34401.1 - 3.3e-22 78.7 47.2 8.4e-20 70.7 31.9 3.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Rod-binding PF10135.4 KPI34401.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Rod binding protein Complex1_LYR PF05347.10 KPI34402.1 - 2.6e-07 30.3 0.2 4.4e-07 29.5 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KPI34402.1 - 7.4e-07 29.6 0.3 1e-06 29.1 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 KPI34402.1 - 4.3e-06 26.8 0.3 6.9e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 Complex1_LYR-like R-HINP1I PF11463.3 KPI34402.1 - 0.047 13.0 0.5 0.19 11.1 0.2 1.8 1 1 1 2 2 2 0 R.HinP1I restriction endonuclease DUF1770 PF08589.5 KPI34403.1 - 3.1e-18 66.2 5.3 4.9e-18 65.5 3.7 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) DUF605 PF04652.11 KPI34403.1 - 4.2 6.6 8.0 5 6.4 5.6 1.0 1 0 0 1 1 1 0 Vta1 like Sugar_tr PF00083.19 KPI34404.1 - 3e-77 260.1 19.7 2.3e-58 197.9 2.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI34404.1 - 1.2e-21 76.8 20.4 1.3e-20 73.4 13.9 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KPI34404.1 - 3e-09 35.6 1.8 7.9e-09 34.2 0.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KPI34404.1 - 1.4e-07 30.2 1.7 1.4e-07 30.2 1.2 2.9 3 1 0 3 3 3 1 MFS/sugar transport protein YrhK PF14145.1 KPI34404.1 - 0.001 18.6 1.1 0.0035 16.9 0.8 1.9 1 0 0 1 1 1 1 YrhK-like protein Pro_CA PF00484.14 KPI34405.1 - 1.3e-09 38.2 0.0 1.7e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Lactamase_B PF00753.22 KPI34406.1 - 8.5e-09 35.3 4.4 1.3e-08 34.7 3.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI34406.1 - 8.5e-05 22.1 0.5 0.00015 21.3 0.4 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KPI34406.1 - 0.0031 17.2 0.1 0.0055 16.4 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RNA_pol_L_2 PF13656.1 KPI34407.1 - 2.2e-25 87.8 0.0 2.8e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KPI34407.1 - 0.00015 20.8 0.0 0.00027 20.0 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Aminotran_4 PF01063.14 KPI34408.1 - 5.4e-25 88.2 0.0 6.1e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV DUF1138 PF06592.8 KPI34408.1 - 0.23 11.5 0.9 0.75 9.8 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1138) Ras PF00071.17 KPI34409.1 - 4.9e-37 126.8 0.0 7.1e-37 126.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KPI34409.1 - 0.00049 20.5 0.0 0.00081 19.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KPI34409.1 - 0.015 14.5 0.0 0.038 13.2 0.0 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family Fungal_trans PF04082.13 KPI34410.1 - 9.3e-19 67.3 0.1 1.5e-18 66.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI34410.1 - 0.0057 16.5 5.7 0.016 15.0 3.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EST1_DNA_bind PF10373.4 KPI34411.1 - 1.1e-36 126.4 0.4 4.8e-36 124.3 0.0 2.0 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KPI34411.1 - 8.2e-18 64.6 0.6 1.8e-17 63.5 0.4 1.6 1 0 0 1 1 1 1 Telomerase activating protein Est1 Evr1_Alr PF04777.8 KPI34411.1 - 0.18 11.7 1.4 0.95 9.4 0.6 2.5 2 1 0 2 2 2 0 Erv1 / Alr family EHN PF06441.7 KPI34412.1 - 2.7e-32 111.0 0.0 4.7e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KPI34412.1 - 6.5e-09 36.0 0.6 2.1e-08 34.3 0.2 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI34412.1 - 2.6e-07 30.4 0.2 6.3e-07 29.1 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans PF04082.13 KPI34413.1 - 1.2e-19 70.1 0.0 1.9e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 KPI34414.1 - 4.7e-20 72.5 0.0 1e-19 71.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI34414.1 - 1.7e-15 56.2 0.0 3.8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI34414.1 - 5.6e-11 42.3 0.0 1.3e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI34414.1 - 9e-07 28.1 0.0 3.4e-05 22.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KPI34414.1 - 0.0013 18.5 0.1 0.097 12.4 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KPI34414.1 - 0.017 14.2 0.0 4.1 6.3 0.0 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Thi4 PF01946.12 KPI34414.1 - 0.09 11.8 0.0 2.1 7.3 0.0 2.4 3 0 0 3 3 3 0 Thi4 family PHO4 PF01384.15 KPI34415.1 - 1e-99 333.2 17.8 1.2e-99 333.0 12.3 1.1 1 0 0 1 1 1 1 Phosphate transporter family NADH_dh_m_C1 PF15088.1 KPI34415.1 - 0.8 9.2 4.1 17 5.0 0.0 3.7 3 0 0 3 3 3 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial ABC2_membrane PF01061.19 KPI34416.1 - 9.8e-78 260.1 57.2 3.2e-39 134.2 15.3 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 KPI34416.1 - 5e-40 136.9 0.0 7.6e-19 68.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KPI34416.1 - 1.4e-23 82.4 0.7 7.3e-18 64.1 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KPI34416.1 - 1.6e-15 56.9 0.1 5.1e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KPI34416.1 - 2.1e-08 33.7 0.1 0.00035 20.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KPI34416.1 - 7.6e-08 32.5 0.8 0.00011 22.2 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 KPI34416.1 - 3.5e-05 23.9 0.0 0.55 10.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KPI34416.1 - 9.8e-05 22.4 0.1 0.084 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KPI34416.1 - 0.00014 21.3 0.9 0.02 14.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KPI34416.1 - 0.00031 19.9 0.1 0.0041 16.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ArgK PF03308.11 KPI34416.1 - 0.00052 18.8 0.1 0.14 10.8 0.0 2.2 2 0 0 2 2 2 1 ArgK protein ABC2_membrane_3 PF12698.2 KPI34416.1 - 0.00097 18.2 19.2 0.00097 18.2 13.3 2.7 2 1 0 2 2 1 1 ABC-2 family transporter protein AAA_18 PF13238.1 KPI34416.1 - 0.0018 18.5 0.2 0.24 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KPI34416.1 - 0.0021 17.5 3.1 0.14 11.5 0.3 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 KPI34416.1 - 0.0039 16.8 0.7 0.37 10.4 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 KPI34416.1 - 0.0044 16.7 0.8 5 6.9 0.3 2.8 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 KPI34416.1 - 0.0047 16.5 1.0 2.7 7.6 0.3 2.9 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.14 KPI34416.1 - 0.0069 15.6 0.0 0.032 13.4 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 KPI34416.1 - 0.0076 16.2 1.4 2.2 8.2 0.4 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KPI34416.1 - 0.011 15.6 0.1 0.94 9.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KPI34416.1 - 0.024 14.1 0.1 0.42 10.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.1 KPI34416.1 - 0.027 14.0 0.1 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KPI34416.1 - 0.052 13.2 0.0 8.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_17 PF13207.1 KPI34416.1 - 0.065 14.0 0.1 1.4 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KPI34416.1 - 0.066 13.7 0.0 14 6.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein ATP-synt_ab PF00006.20 KPI34416.1 - 0.073 12.5 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.13 KPI34416.1 - 0.079 12.4 0.1 14 5.1 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 KPI34416.1 - 0.084 13.0 0.2 13 5.9 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KPI34416.1 - 0.18 11.3 0.1 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KPI34416.1 - 0.4 10.1 2.8 2.1 7.8 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.4 KPI34416.1 - 0.41 9.5 0.0 3.2 6.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.17 KPI34416.1 - 1.2 8.5 2.7 1.4 8.2 0.4 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ADH_zinc_N PF00107.21 KPI34417.1 - 5.1e-12 45.4 0.4 7.3e-10 38.4 0.0 2.5 3 0 0 3 3 3 2 Zinc-binding dehydrogenase Tim54 PF11711.3 KPI34417.1 - 0.075 11.6 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 adh_short PF00106.20 KPI34418.1 - 7.6e-16 58.4 0.0 3.2e-15 56.4 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KPI34418.1 - 0.02 14.5 0.8 1.7 8.2 0.0 2.8 3 1 0 3 3 3 0 KR domain Epimerase PF01370.16 KPI34418.1 - 0.052 12.9 0.1 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Kelch_4 PF13418.1 KPI34418.1 - 0.13 12.0 0.1 23 4.8 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain Fungal_trans_2 PF11951.3 KPI34419.1 - 0.00024 19.8 0.4 0.0011 17.6 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 KPI34420.1 - 1.2e-22 80.4 0.0 1.8e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI34420.1 - 2.9e-11 42.9 0.1 4.8e-05 22.4 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KPI34420.1 - 4.8e-06 26.8 0.1 6.1e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI34420.1 - 0.0015 18.5 0.1 0.0041 17.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI34420.1 - 0.0019 17.1 0.1 0.004 16.0 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.11 KPI34420.1 - 0.0095 15.3 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 KPI34420.1 - 0.023 14.5 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI34420.1 - 0.03 13.2 0.1 0.29 9.9 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 KPI34420.1 - 0.064 12.9 0.1 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.4 KPI34420.1 - 0.064 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain Trp_halogenase PF04820.9 KPI34420.1 - 0.15 10.6 0.5 1.4 7.4 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase adh_short PF00106.20 KPI34421.1 - 1.4e-34 119.3 0.5 1.4e-34 119.3 0.3 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI34421.1 - 3.5e-34 118.6 0.3 4.3e-34 118.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI34421.1 - 8.2e-14 51.6 0.2 1.3e-13 51.0 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI34421.1 - 9.1e-06 25.2 0.0 2.9e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_trans_4_4 PF13579.1 KPI34421.1 - 0.0042 17.2 0.6 1.1 9.3 0.1 2.2 2 1 0 2 2 2 2 Glycosyl transferase 4-like domain DUF1776 PF08643.5 KPI34421.1 - 0.015 14.4 0.0 0.055 12.5 0.0 1.8 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 KPI34421.1 - 0.02 13.9 0.9 0.046 12.8 0.1 2.0 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ACT_7 PF13840.1 KPI34421.1 - 0.02 14.4 0.3 2.9 7.4 0.0 3.0 2 1 0 2 2 2 0 ACT domain AdoHcyase_NAD PF00670.16 KPI34421.1 - 0.021 14.6 0.4 0.075 12.8 0.3 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Toprim_C_rpt PF13368.1 KPI34421.1 - 0.032 14.6 0.6 0.3 11.6 0.0 2.7 4 0 0 4 4 3 0 Topoisomerase C-terminal repeat NAD_binding_10 PF13460.1 KPI34421.1 - 0.041 13.8 2.3 0.16 11.9 1.6 2.1 1 1 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 KPI34421.1 - 0.11 12.1 1.7 0.21 11.2 0.3 1.9 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.17 KPI34422.1 - 1e-75 255.0 0.0 1.3e-75 254.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KPI34422.1 - 6e-31 107.5 0.0 1e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KPI34422.1 - 4.6e-23 81.8 0.0 9.7e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KPI34422.1 - 2.2e-14 53.9 0.0 7.5e-13 49.0 0.0 2.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain PAP2 PF01569.16 KPI34423.1 - 1.6e-15 56.8 4.9 1.6e-15 56.8 3.4 2.5 2 1 0 2 2 2 1 PAP2 superfamily Sugar_tr PF00083.19 KPI34424.1 - 1.3e-90 304.1 18.1 1.6e-90 303.9 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI34424.1 - 7.3e-22 77.5 42.1 4.6e-19 68.3 13.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KPI34424.1 - 0.00048 18.4 4.7 0.00048 18.4 3.2 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.4 KPI34424.1 - 5.5 7.0 9.4 0.47 10.4 1.4 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2530) Fungal_trans PF04082.13 KPI34425.1 - 2.6e-11 42.8 0.2 3.9e-11 42.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF383 PF04063.9 KPI34425.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF383) Cut8_N PF14482.1 KPI34425.1 - 2.5 8.1 4.4 0.82 9.7 1.0 1.8 2 0 0 2 2 2 0 Cut8 proteasome-binding domain adh_short PF00106.20 KPI34427.1 - 3.8e-09 36.6 0.0 6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KPI34427.1 - 0.025 13.9 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Motile_Sperm PF00635.21 KPI34428.1 - 0.0006 19.4 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Gly_radical PF01228.16 KPI34428.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Glycine radical 2OG-FeII_Oxy_2 PF13532.1 KPI34429.1 - 1.4e-12 47.8 0.0 1.8e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_23 PF13489.1 KPI34431.1 - 0.00039 20.1 0.0 0.00059 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Pmp3 PF01679.12 KPI34432.1 - 2.7e-13 49.4 6.8 3.8e-13 48.9 4.7 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Sua5_yciO_yrdC PF01300.13 KPI34433.1 - 8.5e-47 158.6 0.0 1.6e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KPI34433.1 - 2e-18 66.6 0.0 4.7e-18 65.4 0.0 1.6 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding PS_Dcarbxylase PF02666.10 KPI34435.1 - 7.3e-47 159.2 0.0 1e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Glyco_hydro_3 PF00933.16 KPI34437.1 - 1.3e-74 250.8 0.0 1.9e-74 250.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KPI34437.1 - 1.6e-58 197.9 0.0 1.1e-57 195.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KPI34437.1 - 4.6e-21 74.5 0.3 9.5e-21 73.5 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KPI34437.1 - 2.3e-13 50.0 0.1 4.3e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Phage_sheath_1 PF04984.9 KPI34437.1 - 0.042 12.2 0.0 0.069 11.5 0.0 1.3 1 0 0 1 1 1 0 Phage tail sheath protein Pyr_redox_3 PF13738.1 KPI34438.1 - 8.8e-30 104.2 0.0 1.4e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI34438.1 - 7.6e-20 70.5 0.1 2.9e-19 68.6 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KPI34438.1 - 9.6e-13 47.7 0.4 4.2e-11 42.3 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KPI34438.1 - 4.3e-11 42.6 0.0 4.5e-08 32.9 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KPI34438.1 - 2.1e-08 33.0 0.3 0.056 11.9 0.0 3.2 3 0 0 3 3 3 3 HI0933-like protein Pyr_redox_2 PF07992.9 KPI34438.1 - 1.6e-06 28.1 0.0 0.3 10.9 0.0 3.5 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI34438.1 - 2.7e-06 27.2 0.0 0.00021 21.0 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 KPI34438.1 - 2.1e-05 23.7 0.1 0.007 15.4 0.0 3.0 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 KPI34438.1 - 0.00015 20.8 3.6 0.00069 18.6 0.2 2.9 1 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KPI34438.1 - 0.00015 22.0 0.1 0.014 15.7 0.0 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KPI34438.1 - 0.00036 19.7 0.7 0.052 12.5 0.0 2.5 1 1 2 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.1 KPI34438.1 - 0.00069 19.8 0.0 0.057 13.6 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 KPI34438.1 - 0.0051 15.7 0.0 0.031 13.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 KPI34438.1 - 0.0059 16.6 0.1 1.4 9.0 0.0 3.3 4 0 0 4 4 3 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 KPI34438.1 - 0.039 12.8 0.0 0.62 8.9 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 KPI34438.1 - 0.047 12.8 0.0 0.95 8.5 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KPI34438.1 - 0.083 12.4 0.3 7.6 6.0 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.13 KPI34439.1 - 2.9e-12 46.0 1.9 4.2e-12 45.4 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PEP_mutase PF13714.1 KPI34440.1 - 6.1e-51 172.9 0.1 7.5e-51 172.6 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KPI34440.1 - 2.2e-19 69.0 0.2 3.1e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family SPX PF03105.14 KPI34442.1 - 0.00023 21.0 0.8 0.00025 20.9 0.6 1.1 1 0 0 1 1 1 1 SPX domain DUF4407 PF14362.1 KPI34442.1 - 0.0019 17.2 4.6 0.0021 17.0 3.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF745 PF05335.8 KPI34442.1 - 0.014 14.8 4.5 0.018 14.5 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Spb1_C PF07780.7 KPI34442.1 - 0.019 14.4 1.1 0.022 14.2 0.7 1.2 1 0 0 1 1 1 0 Spb1 C-terminal domain Syntaxin-6_N PF09177.6 KPI34442.1 - 0.033 14.6 1.4 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Mut7-C PF01927.11 KPI34442.1 - 0.05 13.5 0.4 0.064 13.2 0.2 1.3 1 1 0 1 1 1 0 Mut7-C RNAse domain NIT PF08376.5 KPI34442.1 - 0.071 12.6 7.9 0.022 14.3 1.3 2.0 1 1 1 2 2 2 0 Nitrate and nitrite sensing DIRP PF06584.8 KPI34442.1 - 0.092 12.6 1.1 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 DIRP Prefoldin PF02996.12 KPI34442.1 - 0.12 12.0 2.7 3.2 7.4 0.1 2.4 2 1 1 3 3 3 0 Prefoldin subunit DUF2229 PF09989.4 KPI34442.1 - 0.33 10.3 1.6 0.47 9.8 1.1 1.5 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) TPR_MLP1_2 PF07926.7 KPI34442.1 - 0.33 10.6 8.9 0.085 12.6 2.8 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 KPI34442.1 - 0.41 10.2 5.4 0.45 10.0 3.8 1.1 1 0 0 1 1 1 0 IncA protein Laminin_II PF06009.7 KPI34442.1 - 0.44 10.3 4.4 1.4 8.7 0.4 2.5 2 1 1 3 3 3 0 Laminin Domain II GrpE PF01025.14 KPI34442.1 - 0.54 9.7 10.0 2.4 7.7 6.9 1.9 1 1 0 1 1 1 0 GrpE YlqD PF11068.3 KPI34442.1 - 1.9 8.5 4.7 6.7 6.7 3.2 1.8 1 1 0 1 1 1 0 YlqD protein DUF883 PF05957.8 KPI34442.1 - 6.2 7.2 12.4 8.1 6.9 0.7 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Mu-like_Pro PF10123.4 KPI34443.1 - 0.088 12.2 1.1 0.12 11.8 0.7 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein Aconitase PF00330.15 KPI34444.1 - 1.1e-58 198.8 0.7 1.7e-40 138.8 0.0 2.6 2 1 0 3 3 3 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KPI34444.1 - 4.6e-14 52.6 0.0 9.3e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Fungal_trans PF04082.13 KPI34445.1 - 1.5e-12 46.9 0.7 1.9e-11 43.3 0.1 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Peptidase_M20 PF01546.23 KPI34446.1 - 7.8e-25 87.4 0.0 7.1e-24 84.3 0.0 2.2 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KPI34446.1 - 4.4e-08 32.7 0.2 0.0036 17.1 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat M20_dimer PF07687.9 KPI34446.1 - 2.7e-06 27.0 0.1 9.5e-06 25.3 0.1 2.0 1 1 0 1 1 1 1 Peptidase dimerisation domain PQQ_2 PF13360.1 KPI34446.1 - 5.9e-05 22.6 0.1 0.00057 19.4 0.1 2.2 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 KPI34446.1 - 0.033 14.4 0.8 7.9 6.9 0.2 3.4 2 0 0 2 2 2 0 PQQ-like domain DEAD PF00270.24 KPI34447.1 - 1.7e-40 138.3 0.1 4.8e-40 136.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI34447.1 - 1.8e-22 78.9 0.1 5.7e-22 77.3 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI34447.1 - 0.0056 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 KPI34447.1 - 0.091 11.6 0.3 0.16 10.8 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein HAD_2 PF13419.1 KPI34448.1 - 2.1e-25 89.9 0.0 2.7e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase TPR_14 PF13428.1 KPI34448.1 - 3.1 8.7 5.9 30 5.6 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat FbpA PF05833.6 KPI34449.1 - 1.4e-30 106.2 16.3 9.6e-25 87.0 0.0 2.9 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 KPI34449.1 - 5e-29 100.1 1.0 4.4e-28 97.1 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 KPI34449.1 - 3.9e-17 61.9 0.0 1.3e-16 60.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF814) adh_short PF00106.20 KPI34450.1 - 1.2e-12 48.0 1.0 1.2e-12 48.0 0.7 2.2 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI34450.1 - 0.003 17.3 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI34450.1 - 0.0054 16.4 0.3 0.0054 16.4 0.2 2.7 3 1 0 3 3 3 1 KR domain Eno-Rase_NADH_b PF12242.3 KPI34450.1 - 0.011 15.5 0.2 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KPI34450.1 - 0.1 11.9 1.7 0.31 10.4 0.0 2.4 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family EBP PF05241.7 KPI34452.1 - 2.9e-51 173.2 9.6 3.7e-51 172.9 6.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein Fungal_trans PF04082.13 KPI34453.1 - 0.0067 15.3 0.1 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fusion_gly PF00523.13 KPI34453.1 - 0.017 13.2 0.0 0.028 12.4 0.0 1.4 1 0 0 1 1 1 0 Fusion glycoprotein F0 PTR2 PF00854.16 KPI34454.1 - 2.2e-54 184.7 10.4 1.4e-53 182.0 7.2 2.1 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 KPI34454.1 - 3.4e-06 26.0 19.0 3.4e-06 26.0 13.1 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily CENP-T PF15511.1 KPI34455.1 - 0.041 13.1 17.8 0.07 12.3 12.4 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SAPS PF04499.10 KPI34455.1 - 0.41 9.2 2.7 0.44 9.1 1.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Trypan_PARP PF05887.6 KPI34455.1 - 1.6 8.5 17.1 3 7.6 10.3 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Daxx PF03344.10 KPI34455.1 - 1.6 7.1 15.3 2 6.7 10.6 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 KPI34455.1 - 8.2 5.7 14.0 15 4.8 9.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 KPI34455.1 - 8.4 4.1 16.1 14 3.4 11.1 1.2 1 0 0 1 1 1 0 Nop14-like family Acetyltransf_1 PF00583.19 KPI34456.1 - 3.4e-11 43.0 0.1 1.1e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI34456.1 - 3.5e-11 43.0 0.1 1.2e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI34456.1 - 3e-05 24.1 0.0 5.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KPI34456.1 - 0.0018 18.1 0.0 0.01 15.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KPI34456.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MOZ_SAS PF01853.13 KPI34456.1 - 0.15 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family ABC_tran PF00005.22 KPI34457.1 - 3.1e-44 150.5 0.0 7.5e-23 81.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KPI34457.1 - 8.6e-31 107.3 38.8 4.2e-21 75.5 10.3 2.7 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KPI34457.1 - 2.1e-13 50.0 0.4 0.00011 21.5 0.2 4.1 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KPI34457.1 - 5.9e-11 42.8 0.2 0.05 13.5 0.0 4.3 2 2 1 3 3 3 3 AAA domain AAA_16 PF13191.1 KPI34457.1 - 1.6e-07 31.5 0.2 0.026 14.5 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KPI34457.1 - 4.4e-07 29.3 1.4 0.0067 15.9 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KPI34457.1 - 2.7e-06 27.5 1.1 0.009 16.1 0.1 3.4 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KPI34457.1 - 7.2e-06 25.9 0.3 0.0093 15.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KPI34457.1 - 8.8e-06 25.3 1.9 0.0041 16.6 0.1 3.3 3 0 0 3 3 3 1 AAA-like domain DUF258 PF03193.11 KPI34457.1 - 2.9e-05 23.3 0.1 0.24 10.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KPI34457.1 - 8.3e-05 23.4 0.3 0.12 13.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KPI34457.1 - 8.9e-05 22.0 0.1 0.046 13.1 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 KPI34457.1 - 0.00011 22.1 0.0 0.47 10.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.24 KPI34457.1 - 0.00024 21.3 0.1 0.33 11.1 0.0 3.8 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KPI34457.1 - 0.0006 19.5 0.2 2 8.1 0.0 3.1 4 0 0 4 4 2 2 AAA domain (dynein-related subfamily) T2SE PF00437.15 KPI34457.1 - 0.00068 18.6 0.0 0.05 12.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 KPI34457.1 - 0.0012 18.5 0.2 0.86 9.3 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KPI34457.1 - 0.0018 18.6 1.1 0.15 12.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KPI34457.1 - 0.002 18.6 0.1 3 8.3 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 KPI34457.1 - 0.0035 17.6 0.0 2.5 8.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 KPI34457.1 - 0.0064 16.2 0.3 0.22 11.2 0.0 3.5 4 0 0 4 4 3 1 Part of AAA domain NACHT PF05729.7 KPI34457.1 - 0.0075 15.9 0.1 0.42 10.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Sigma54_activat PF00158.21 KPI34457.1 - 0.0076 15.7 0.0 0.49 9.8 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 KPI34457.1 - 0.0085 15.5 1.0 1.4 8.3 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.1 KPI34457.1 - 0.0086 15.6 0.2 3.2 7.2 0.0 3.4 4 0 0 4 4 3 1 AAA domain TrwB_AAD_bind PF10412.4 KPI34457.1 - 0.0087 14.7 0.1 0.27 9.8 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.12 KPI34457.1 - 0.011 15.6 1.6 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 cobW PF02492.14 KPI34457.1 - 0.014 14.8 0.3 0.11 11.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 KPI34457.1 - 0.017 13.9 0.0 1 8.1 0.1 2.6 2 1 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 KPI34457.1 - 0.025 14.3 0.2 0.077 12.6 0.0 1.9 2 0 0 2 2 1 0 Archaeal ATPase Mg_chelatase PF01078.16 KPI34457.1 - 0.028 13.5 0.0 0.43 9.7 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 KPI34457.1 - 0.029 13.2 0.1 2.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 KPI34457.1 - 0.039 13.0 0.1 8.9 5.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 KPI34457.1 - 0.062 13.2 0.1 0.24 11.2 0.0 2.1 3 0 0 3 3 1 0 AAA domain Pox_A32 PF04665.7 KPI34457.1 - 0.063 12.5 0.1 3 7.0 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein NTPase_1 PF03266.10 KPI34457.1 - 0.067 12.8 1.2 9.2 5.9 0.0 3.3 3 0 0 3 3 3 0 NTPase ATP_bind_1 PF03029.12 KPI34457.1 - 0.073 12.5 0.3 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KPI34457.1 - 0.076 12.4 0.3 1.6 8.1 0.0 2.9 4 0 0 4 4 2 0 Elongation factor Tu GTP binding domain RNA_helicase PF00910.17 KPI34457.1 - 0.099 12.8 0.3 19 5.4 0.0 2.9 3 0 0 3 3 2 0 RNA helicase Dynamin_N PF00350.18 KPI34457.1 - 0.11 12.3 0.5 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Adeno_IVa2 PF02456.10 KPI34457.1 - 0.11 11.0 0.0 0.23 10.0 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein UPF0079 PF02367.12 KPI34457.1 - 0.11 12.0 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 KPI34457.1 - 0.12 12.3 0.1 1.8 8.5 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Guanylate_kin PF00625.16 KPI34457.1 - 0.21 11.0 0.0 0.6 9.5 0.0 1.7 2 0 0 2 2 2 0 Guanylate kinase Motile_Sperm PF00635.21 KPI34458.1 - 4.4e-11 42.3 0.0 7e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Auto_anti-p27 PF06677.7 KPI34459.1 - 4.1 7.2 6.2 0.4 10.4 0.7 2.0 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Mito_carr PF00153.22 KPI34460.1 - 2.7e-54 180.8 0.9 3.4e-20 71.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FAD_binding_2 PF00890.19 KPI34461.1 - 3.7e-44 151.2 0.5 4.4e-43 147.6 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI34461.1 - 5.6e-09 35.3 1.6 1.1e-08 34.3 0.0 2.1 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KPI34461.1 - 5.2e-07 29.0 0.1 4.2e-06 26.1 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KPI34461.1 - 4.6e-05 22.5 0.0 6.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KPI34461.1 - 0.00016 21.5 0.1 0.00052 19.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KPI34461.1 - 0.00017 20.1 0.1 0.0017 16.9 0.0 2.4 3 0 0 3 3 3 1 HI0933-like protein GMC_oxred_N PF00732.14 KPI34461.1 - 0.00037 19.7 0.0 0.034 13.3 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 KPI34461.1 - 0.0026 17.6 0.3 0.011 15.6 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI34461.1 - 0.0032 16.5 0.0 0.0072 15.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 KPI34461.1 - 0.0084 15.0 2.1 0.031 13.1 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KPI34461.1 - 0.014 15.7 0.0 11 6.5 0.0 3.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DBR1 PF05011.8 KPI34461.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain ApoO PF09769.4 KPI34463.1 - 8.2e-42 142.5 0.4 1.2e-41 142.0 0.0 1.5 2 0 0 2 2 2 1 Apolipoprotein O VHS PF00790.14 KPI34464.1 - 2.7e-18 65.9 0.0 5.7e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 KPI34464.1 - 5.3e-10 39.1 0.2 1.8e-09 37.5 0.1 1.9 1 0 0 1 1 1 1 GAT domain ENTH PF01417.15 KPI34464.1 - 0.0007 19.4 0.0 0.011 15.5 0.0 2.4 2 1 1 3 3 3 1 ENTH domain ArfGap PF01412.13 KPI34465.1 - 6.4e-42 142.0 1.0 9.2e-42 141.5 0.7 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf NicO PF03824.11 KPI34466.1 - 1.3e-51 175.5 20.6 7.7e-50 169.7 7.4 2.7 3 0 0 3 3 3 2 High-affinity nickel-transport protein GFA PF04828.9 KPI34467.1 - 2e-21 75.7 0.0 2.8e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme PSDC PF12588.3 KPI34468.1 - 1.6e-49 167.1 0.0 2.5e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 KPI34468.1 - 1.4e-36 125.6 0.0 2e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 KPI34468.1 - 0.00038 20.0 0.4 0.22 11.2 0.1 2.3 2 0 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.17 KPI34468.1 - 0.065 12.8 0.1 0.62 9.7 0.1 2.2 2 0 0 2 2 2 0 Biotin-requiring enzyme RnfC_N PF13375.1 KPI34468.1 - 0.099 12.3 0.1 14 5.5 0.0 2.4 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain RIO1 PF01163.17 KPI34469.1 - 7e-68 227.7 0.7 7e-68 227.7 0.5 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KPI34469.1 - 0.0017 18.1 0.3 0.24 11.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KPI34469.1 - 0.018 14.1 0.7 2.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pneumo_att_G PF05539.6 KPI34469.1 - 0.33 10.2 8.2 0.49 9.7 5.7 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Aldolase_II PF00596.16 KPI34470.1 - 6e-30 104.2 0.3 1e-29 103.4 0.2 1.3 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Tht1 PF04163.7 KPI34471.1 - 0.002 16.6 0.5 0.0057 15.0 0.2 1.9 2 0 0 2 2 2 1 Tht1-like nuclear fusion protein SMC_N PF02463.14 KPI34472.1 - 1.4e-48 165.0 46.0 6.8e-48 162.7 31.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KPI34472.1 - 1.2e-29 102.7 0.1 1.5e-28 99.1 0.0 3.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KPI34472.1 - 1e-13 51.9 10.7 9.9e-08 32.2 0.1 3.8 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 KPI34472.1 - 1.9e-13 51.2 27.8 1.9e-13 51.2 19.3 7.3 3 3 3 6 6 6 1 AAA domain AAA_29 PF13555.1 KPI34472.1 - 0.0016 17.9 0.0 0.0044 16.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain KIP1 PF07765.7 KPI34472.1 - 0.074 12.8 0.2 0.074 12.8 0.1 3.3 3 0 0 3 3 3 0 KIP1-like protein AAA_13 PF13166.1 KPI34472.1 - 0.1 11.0 0.0 0.1 11.0 0.0 6.0 3 2 3 6 6 6 0 AAA domain Reo_sigmaC PF04582.7 KPI34472.1 - 0.28 10.3 29.8 0.026 13.7 1.4 5.4 4 1 0 5 5 5 0 Reovirus sigma C capsid protein Dfp1_Him1_M PF08630.5 KPI34473.1 - 2.4e-32 111.3 0.0 5.5e-32 110.1 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 KPI34473.1 - 1.4e-24 85.4 0.4 2.6e-24 84.6 0.3 1.4 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 KPI34473.1 - 0.027 14.3 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain Methyltransf_26 PF13659.1 KPI34474.1 - 1.7e-13 50.6 0.1 2.7e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KPI34474.1 - 0.00044 19.6 0.5 0.0008 18.8 0.4 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KPI34474.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NTP_transferase PF00483.18 KPI34475.1 - 2.2e-27 95.9 0.0 2.8e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 KPI34475.1 - 4.7e-08 32.1 8.7 2.8e-05 23.4 0.1 3.8 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Glycos_transf_2 PF00535.21 KPI34475.1 - 0.024 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF2968 PF11180.3 KPI34475.1 - 0.12 11.6 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Abhydrolase_4 PF08386.5 KPI34476.1 - 5.8e-14 51.8 0.0 1.6e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KPI34476.1 - 3.8e-13 49.5 0.0 3.3e-12 46.4 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI34476.1 - 0.0001 22.2 0.1 0.00068 19.5 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Pkinase PF00069.20 KPI34477.1 - 1.4e-16 60.4 0.0 1e-15 57.6 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI34477.1 - 4.5e-06 25.9 0.1 0.016 14.2 0.0 3.3 2 2 0 2 2 2 2 Protein tyrosine kinase APG17 PF04108.7 KPI34478.1 - 6.1e-86 288.7 2.8 7e-86 288.5 1.9 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Pex19 PF04614.7 KPI34478.1 - 0.019 14.5 1.7 0.036 13.6 0.4 2.0 2 1 0 2 2 2 0 Pex19 protein family Prominin PF05478.6 KPI34478.1 - 0.023 12.2 4.4 0.17 9.3 0.4 2.6 2 1 0 2 2 2 0 Prominin DUF3829 PF12889.2 KPI34478.1 - 0.051 12.7 1.3 0.21 10.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) GET2 PF08690.5 KPI34478.1 - 0.069 12.3 0.7 0.13 11.4 0.5 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 Allexi_40kDa PF05549.6 KPI34478.1 - 0.077 12.2 6.1 0.57 9.4 0.1 3.0 1 1 2 3 3 3 0 Allexivirus 40kDa protein NPV_P10 PF05531.7 KPI34478.1 - 0.2 11.9 5.7 3.3 8.0 0.6 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Med10 PF09748.4 KPI34478.1 - 0.25 11.1 2.2 0.98 9.2 0.6 2.6 2 1 1 3 3 3 0 Transcription factor subunit Med10 of Mediator complex Bacillus_HBL PF05791.6 KPI34478.1 - 0.29 10.4 3.4 1.7 8.0 0.4 3.0 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Snapin_Pallidin PF14712.1 KPI34478.1 - 0.7 10.2 7.9 9.1 6.6 0.9 4.4 6 0 0 6 6 6 0 Snapin/Pallidin DUF1664 PF07889.7 KPI34478.1 - 1.1 9.0 10.5 3.3 7.5 1.3 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Med9 PF07544.8 KPI34478.1 - 2 8.2 5.9 5.7 6.7 0.6 3.8 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Fib_alpha PF08702.5 KPI34478.1 - 2.7 8.0 5.4 9.1 6.3 0.3 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family IncA PF04156.9 KPI34478.1 - 6.6 6.2 14.6 2.3 7.7 0.7 3.2 2 1 0 3 3 3 0 IncA protein WD40 PF00400.27 KPI34479.1 - 3.2e-62 204.3 24.4 3.9e-10 39.1 0.0 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KPI34479.1 - 2.2e-12 46.5 0.3 5.2e-12 45.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KPI34479.1 - 5.1e-10 38.7 0.1 1.1e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KPI34479.1 - 3.4e-07 28.8 13.3 0.048 11.7 0.1 5.4 2 2 4 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KPI34479.1 - 0.078 11.7 1.8 13 4.3 0.1 3.4 2 1 1 4 4 4 0 Nup133 N terminal like MFS_1 PF07690.11 KPI34480.1 - 4.3e-25 88.1 30.0 4.3e-25 88.1 20.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2556 PF10831.3 KPI34480.1 - 2.1 8.0 6.2 35 4.1 2.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2556) Inositol_P PF00459.20 KPI34481.1 - 8.8e-54 182.6 2.5 2.1e-53 181.3 1.7 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family Pkinase PF00069.20 KPI34482.1 - 1.1e-55 188.6 0.0 1.7e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI34482.1 - 1.3e-33 116.1 0.0 1.8e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI34482.1 - 0.00028 19.9 0.0 0.00042 19.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KPI34482.1 - 0.00033 19.7 0.1 0.00067 18.7 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KPI34482.1 - 0.001 18.8 1.2 0.0018 18.0 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Zds_C PF08632.5 KPI34483.1 - 1.9e-30 104.0 1.3 3.5e-30 103.1 0.9 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term LCD1 PF09798.4 KPI34483.1 - 0.78 7.6 1.4 1.1 7.1 1.0 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein CsbD PF05532.7 KPI34484.1 - 0.11 12.1 4.9 0.3 10.7 3.4 1.7 1 0 0 1 1 1 0 CsbD-like F-box-like PF12937.2 KPI34485.1 - 0.00019 21.0 0.0 0.0004 20.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.12 KPI34485.1 - 0.014 15.2 0.2 0.22 11.5 0.2 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 KPI34485.1 - 0.018 14.6 0.3 0.036 13.7 0.2 1.5 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.23 KPI34485.1 - 0.058 13.0 0.1 13 5.6 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 KPI34485.1 - 0.093 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain p450 PF00067.17 KPI34486.1 - 4.9e-62 209.9 0.0 6.3e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 KPI34487.1 - 0.0064 16.1 1.7 0.07 12.8 1.2 2.2 1 1 0 1 1 1 1 F-box-like DUF2735 PF10931.3 KPI34487.1 - 0.039 14.2 0.2 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2735) DASH_Duo1 PF08651.5 KPI34488.1 - 0.013 15.1 0.0 0.03 13.8 0.0 1.6 1 1 0 1 1 1 0 DASH complex subunit Duo1 Podoplanin PF05808.6 KPI34488.1 - 0.028 13.9 0.4 0.045 13.3 0.2 1.5 1 1 0 1 1 1 0 Podoplanin Rootletin PF15035.1 KPI34488.1 - 0.047 13.6 0.2 0.048 13.6 0.1 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion PepSY_TM_3 PF13706.1 KPI34488.1 - 0.56 9.6 6.8 0.93 8.9 4.7 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix CTP_synth_N PF06418.9 KPI34489.1 - 6e-118 392.9 0.1 8.2e-118 392.4 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KPI34489.1 - 2.1e-54 183.9 0.0 3.2e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KPI34489.1 - 1.9e-07 30.7 0.0 5.9e-07 29.1 0.0 1.9 1 1 1 2 2 2 1 Peptidase C26 CbiA PF01656.18 KPI34489.1 - 0.035 13.5 0.0 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ribosomal_L6 PF00347.18 KPI34490.1 - 4.7e-24 84.6 0.0 2.7e-14 53.4 0.0 2.7 3 0 0 3 3 3 2 Ribosomal protein L6 Sugar_tr PF00083.19 KPI34492.1 - 3.8e-99 332.3 21.4 4.2e-99 332.1 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI34492.1 - 1.6e-16 59.9 16.0 1.6e-16 59.9 11.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 KPI34493.1 - 1.6e-35 122.5 44.8 1.3e-33 116.2 12.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI34493.1 - 5e-10 38.5 2.5 5e-10 38.5 1.7 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KPI34493.1 - 0.011 13.9 0.2 0.011 13.9 0.1 2.4 2 1 1 3 3 3 0 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.13 KPI34493.1 - 0.025 13.0 0.1 0.053 12.0 0.0 1.4 1 0 0 1 1 1 0 Reduced folate carrier MFS_2 PF13347.1 KPI34493.1 - 0.15 10.4 19.4 0.041 12.2 1.2 2.4 2 0 0 2 2 2 0 MFS/sugar transport protein RTA1 PF04479.8 KPI34494.1 - 2.6e-45 154.6 2.0 3.3e-45 154.3 1.4 1.1 1 0 0 1 1 1 1 RTA1 like protein CD34_antigen PF06365.7 KPI34494.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Bac_luciferase PF00296.15 KPI34495.1 - 5.5e-37 127.5 0.2 6e-37 127.4 0.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase FAD_binding_3 PF01494.14 KPI34497.1 - 2e-25 89.6 0.0 1.7e-13 50.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KPI34497.1 - 2.6e-05 24.1 2.0 0.00083 19.3 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI34497.1 - 0.00048 19.1 1.1 0.017 14.0 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.5 KPI34497.1 - 0.0078 15.0 0.0 0.024 13.4 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase HI0933_like PF03486.9 KPI34497.1 - 0.026 13.0 0.0 0.11 10.8 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 KPI34497.1 - 0.039 13.7 0.1 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KPI34497.1 - 0.05 12.2 0.1 0.8 8.2 0.1 2.3 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 KPI34497.1 - 0.07 13.1 0.5 2.5 8.1 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI34497.1 - 0.073 11.9 0.4 0.15 10.9 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 KPI34497.1 - 0.15 10.9 0.0 2.5 6.9 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein FAA_hydrolase PF01557.13 KPI34498.1 - 3.1e-51 173.9 0.0 4.3e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Tnp_P_element_C PF12596.3 KPI34498.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 87kDa Transposase Transp_cyt_pur PF02133.10 KPI34499.1 - 6.4e-67 226.0 40.4 7.3e-67 225.8 28.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ATP-synt_J PF04911.7 KPI34499.1 - 0.12 11.7 0.6 0.44 10.0 0.4 1.9 1 0 0 1 1 1 0 ATP synthase j chain MFS_1 PF07690.11 KPI34500.1 - 3.7e-30 104.8 22.7 5.9e-30 104.1 15.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily LicD PF04991.8 KPI34501.1 - 2.6e-34 119.1 5.3 1.9e-33 116.3 3.7 2.0 1 1 0 1 1 1 1 LicD family NMO PF03060.10 KPI34502.1 - 3.9e-38 131.4 6.6 1.9e-37 129.1 4.6 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KPI34502.1 - 0.0052 15.7 0.1 1.9 7.2 1.2 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KPI34502.1 - 0.012 14.5 0.5 0.017 14.0 0.3 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase Epimerase PF01370.16 KPI34503.1 - 2.1e-05 24.0 0.0 2.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI34503.1 - 0.028 14.4 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding ADH_N PF08240.7 KPI34504.1 - 6e-10 38.8 0.0 1.1e-08 34.7 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI34504.1 - 1.5e-08 34.2 0.1 3.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MSP1b PF03429.8 KPI34504.1 - 0.0094 13.8 0.5 0.015 13.2 0.3 1.2 1 0 0 1 1 1 1 Major surface protein 1B GRDA PF04723.9 KPI34504.1 - 0.097 12.3 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A CFEM PF05730.6 KPI34505.1 - 6.5e-12 45.1 8.3 1.2e-11 44.2 5.8 1.5 1 0 0 1 1 1 1 CFEM domain IDO PF01231.13 KPI34506.1 - 4.8e-43 147.1 0.0 7.3e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Sugar_tr PF00083.19 KPI34507.1 - 4.5e-38 130.9 22.8 1e-37 129.7 15.8 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI34507.1 - 2.1e-28 99.0 26.9 2.1e-28 99.0 18.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KPI34507.1 - 0.0099 15.6 0.3 0.13 12.0 0.0 2.7 2 0 0 2 2 2 1 MFS_1 like family DUF4212 PF13937.1 KPI34507.1 - 0.029 14.3 1.2 0.15 12.1 0.9 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) PrpF PF04303.8 KPI34508.1 - 1.7e-35 122.4 1.7 1.9e-35 122.3 1.2 1.0 1 0 0 1 1 1 1 PrpF protein Pro_racemase PF05544.6 KPI34508.1 - 0.015 14.1 0.3 0.017 13.9 0.2 1.0 1 0 0 1 1 1 0 Proline racemase LRR_adjacent PF08191.6 KPI34508.1 - 0.075 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 LRR adjacent Mito_carr PF00153.22 KPI34509.1 - 2.6e-55 184.1 6.9 5.8e-20 70.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein P5CR_dimer PF14748.1 KPI34509.1 - 0.008 16.1 0.2 0.027 14.4 0.1 1.9 1 1 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation DUF1974 PF09317.6 KPI34509.1 - 0.027 13.8 0.2 0.047 13.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Fungal_trans PF04082.13 KPI34510.1 - 1.1e-05 24.4 0.0 2.1e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain VacA PF02691.10 KPI34510.1 - 0.026 12.1 0.4 0.036 11.7 0.3 1.1 1 0 0 1 1 1 0 Vacuolating cyotoxin PepSY_TM_3 PF13706.1 KPI34510.1 - 0.061 12.7 0.9 0.13 11.7 0.6 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix P5CR_dimer PF14748.1 KPI34511.1 - 0.014 15.4 0.0 0.033 14.2 0.0 1.7 1 1 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation DUF4286 PF14114.1 KPI34512.1 - 0.016 15.4 0.1 0.048 13.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) Fungal_trans PF04082.13 KPI34513.1 - 7.8e-26 90.4 0.0 1.1e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Prp18 PF02840.10 KPI34513.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Prp18 domain Bac_luciferase PF00296.15 KPI34514.1 - 2.3e-53 181.3 0.0 3.1e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF2673 PF10880.3 KPI34515.1 - 0.043 13.8 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) Oxidored_FMN PF00724.15 KPI34516.1 - 6.8e-68 229.1 0.0 1.1e-66 225.1 0.0 2.2 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FAD_binding_7 PF03441.9 KPI34517.1 - 3.1e-102 341.5 0.2 4.6e-102 340.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KPI34517.1 - 4.4e-36 124.1 0.0 7.6e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Isochorismatase PF00857.15 KPI34518.1 - 2.5e-22 79.6 0.0 3e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DDE_Tnp_1_7 PF13843.1 KPI34518.1 - 0.023 13.7 0.0 0.031 13.3 0.0 1.1 1 0 0 1 1 1 0 Transposase IS4 MFS_1 PF07690.11 KPI34519.1 - 1.1e-39 136.1 26.3 1.1e-39 136.1 18.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI34519.1 - 8.4e-17 60.8 5.5 8.4e-17 60.8 3.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KPI34519.1 - 2.7e-06 25.8 0.2 2.7e-06 25.8 0.1 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KPI34519.1 - 0.0017 16.5 0.4 0.0017 16.5 0.3 2.1 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.13 KPI34520.1 - 1.6e-26 92.7 0.1 2.3e-26 92.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PrpF PF04303.8 KPI34520.1 - 1e-15 57.3 0.3 1.7e-15 56.6 0.2 1.3 1 0 0 1 1 1 1 PrpF protein EHN PF06441.7 KPI34521.1 - 4.7e-39 132.7 0.7 9.4e-39 131.8 0.5 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KPI34521.1 - 4.4e-09 36.5 1.2 5e-09 36.3 0.2 1.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI34521.1 - 2.6e-06 27.1 0.1 6.9e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI34521.1 - 0.0073 16.0 0.0 0.015 15.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Mrr_cat PF04471.7 KPI34521.1 - 0.044 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Restriction endonuclease Trypsin_2 PF13365.1 KPI34522.1 - 0.033 14.1 0.0 0.071 13.1 0.0 1.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain zf-C2H2 PF00096.21 KPI34523.1 - 1.4e-06 28.2 11.9 0.0083 16.4 3.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI34523.1 - 5.8e-06 26.2 11.1 0.003 17.7 3.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KPI34523.1 - 5.4e-05 23.2 16.1 0.00028 21.0 1.7 3.4 3 0 0 3 3 3 2 Zinc-finger double domain GMC_oxred_N PF00732.14 KPI34524.1 - 4.7e-46 157.2 0.0 1.9e-43 148.7 0.0 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI34524.1 - 1e-34 119.8 0.0 2e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KPI34524.1 - 8.2e-06 24.9 0.1 1.2e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KPI34524.1 - 1.8e-05 23.8 0.3 0.014 14.3 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI34524.1 - 0.00099 18.0 0.2 0.029 13.2 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KPI34524.1 - 0.0018 18.1 0.0 0.0072 16.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI34524.1 - 0.0077 16.2 0.1 0.027 14.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KPI34524.1 - 0.13 11.2 0.0 0.47 9.5 0.0 1.8 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 KPI34524.1 - 0.23 9.8 0.0 0.42 9.0 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Aldedh PF00171.17 KPI34525.1 - 1.6e-131 438.8 0.6 1.9e-131 438.6 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KPI34525.1 - 0.00021 20.6 0.0 0.0028 16.9 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) LuxC PF05893.9 KPI34525.1 - 0.00041 19.1 0.2 0.0017 17.1 0.1 1.9 1 1 1 2 2 2 1 Acyl-CoA reductase (LuxC) Ank_2 PF12796.2 KPI34526.1 - 5.7e-79 260.5 1.3 2.1e-16 60.0 0.1 6.8 5 2 2 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KPI34526.1 - 2.8e-51 168.8 10.0 0.0002 21.0 0.0 15.2 15 0 0 15 15 15 13 Ankyrin repeat Ank_3 PF13606.1 KPI34526.1 - 2.5e-42 138.6 6.3 0.0015 18.6 0.0 14.6 15 0 0 15 15 15 10 Ankyrin repeat Ank_5 PF13857.1 KPI34526.1 - 4.8e-41 137.8 4.0 7.6e-07 29.1 0.0 10.2 6 3 6 12 12 12 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 KPI34526.1 - 2.3e-40 136.2 3.3 1.1e-06 28.9 0.0 10.7 5 3 6 11 11 11 10 Ankyrin repeats (many copies) adh_short PF00106.20 KPI34527.1 - 1.6e-16 60.6 1.9 1.5e-15 57.5 1.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI34527.1 - 4e-06 26.7 0.0 3.7e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI34527.1 - 0.00015 21.5 0.1 0.00026 20.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KPI34527.1 - 0.00041 20.4 0.0 0.00064 19.8 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 KPI34527.1 - 0.0073 16.0 1.7 0.0073 16.0 1.1 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.11 KPI34527.1 - 0.021 14.2 0.3 0.88 8.9 0.1 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 KPI34529.1 - 2.3e-09 37.3 0.0 5.1e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI34529.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 KR domain PmbA_TldD PF01523.11 KPI34529.1 - 0.03 13.6 0.5 2.2 7.4 0.0 2.2 1 1 1 2 2 2 0 Putative modulator of DNA gyrase TrkA_N PF02254.13 KPI34529.1 - 0.041 13.8 0.1 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain NmrA PF05368.8 KPI34529.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family SnoaL PF07366.7 KPI34530.1 - 6.9e-05 22.4 0.0 0.00041 19.9 0.0 2.0 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KPI34530.1 - 0.00026 21.3 0.0 0.00041 20.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain UDPGT PF00201.13 KPI34533.1 - 2.5e-15 56.0 0.0 3.6e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase R3H-assoc PF13902.1 KPI34533.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 R3H-associated N-terminal domain Peptidase_M13_N PF05649.8 KPI34534.1 - 1.3e-69 235.1 0.0 1.8e-66 224.7 0.0 2.3 1 1 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KPI34534.1 - 8.8e-57 191.6 0.1 1.4e-56 190.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 TRI12 PF06609.8 KPI34535.1 - 1.2e-23 83.2 27.6 1.5e-23 82.8 19.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI34535.1 - 2.9e-16 59.1 54.6 2.9e-16 59.1 37.8 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KPI34535.1 - 0.00015 20.3 4.5 0.00015 20.3 3.1 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein HlyD_2 PF12700.2 KPI34536.1 - 0.019 14.1 0.8 0.024 13.7 0.5 1.1 1 0 0 1 1 1 0 HlyD family secretion protein IL2 PF00715.12 KPI34536.1 - 0.044 13.5 0.5 0.077 12.7 0.0 1.6 2 0 0 2 2 2 0 Interleukin 2 FERM_M PF00373.13 KPI34536.1 - 0.069 13.3 2.7 0.19 11.9 1.9 1.8 1 1 0 1 1 1 0 FERM central domain ABC2_membrane PF01061.19 KPI34536.1 - 0.21 10.7 8.1 0.33 10.0 5.6 1.2 1 0 0 1 1 1 0 ABC-2 type transporter DUF805 PF05656.9 KPI34536.1 - 9 6.1 7.4 4 7.2 2.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF805) Pyridox_oxidase PF01243.15 KPI34537.1 - 0.00067 19.6 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TFR_dimer PF04253.10 KPI34538.1 - 2.8e-18 65.7 0.0 4.5e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KPI34538.1 - 4.3e-16 59.1 0.0 8.6e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KPI34538.1 - 0.00015 21.4 0.0 0.00015 21.4 0.0 2.4 3 0 0 3 3 3 1 PA domain Peptidase_M20 PF01546.23 KPI34538.1 - 0.00089 18.8 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Aldedh PF00171.17 KPI34539.1 - 1.2e-183 610.7 0.6 1.3e-183 610.5 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Amidohydro_2 PF04909.9 KPI34540.1 - 6e-24 85.0 0.0 1.1e-23 84.2 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase adh_short PF00106.20 KPI34541.1 - 3.2e-22 79.2 0.0 3.8e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI34541.1 - 5e-09 36.2 0.0 6.8e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI34541.1 - 3.2e-07 30.1 0.1 5.2e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI34541.1 - 1.3e-05 24.7 0.1 6.1e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI34541.1 - 0.0018 18.3 0.1 0.0035 17.3 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 KPI34541.1 - 0.0091 15.5 0.3 0.056 13.0 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Asp_protease_2 PF13650.1 KPI34542.1 - 1.2e-07 32.1 0.0 0.027 14.9 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease Asp_protease PF09668.5 KPI34542.1 - 1.8e-06 27.5 0.0 0.00071 19.1 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 KPI34542.1 - 0.00085 19.0 0.3 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease DUF1221 PF06760.6 KPI34542.1 - 0.0035 16.6 0.4 0.0064 15.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1221) RVP PF00077.15 KPI34542.1 - 0.0046 16.8 0.0 1.3 8.9 0.0 2.7 2 1 0 2 2 2 2 Retroviral aspartyl protease SnoaL_4 PF13577.1 KPI34543.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain NUC153 PF08159.7 KPI34544.1 - 1.4e-09 37.3 0.9 2.6e-08 33.3 0.0 2.7 2 0 0 2 2 2 1 NUC153 domain Eaf7 PF07904.8 KPI34544.1 - 4.3 7.3 6.8 3.5 7.6 0.1 3.5 3 0 0 3 3 3 0 Chromatin modification-related protein EAF7 Fungal_trans PF04082.13 KPI34545.1 - 4.1e-18 65.1 0.5 9.3e-18 64.0 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Slx4 PF09494.5 KPI34545.1 - 0.0042 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Slx4 endonuclease FAD_binding_3 PF01494.14 KPI34546.1 - 2.1e-21 76.3 0.0 1.2e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KPI34546.1 - 9e-07 28.1 7.9 0.0041 16.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI34546.1 - 1.1e-05 25.4 1.3 3.3e-05 23.8 0.9 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KPI34546.1 - 7e-05 21.6 0.0 7e-05 21.6 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase Amino_oxidase PF01593.19 KPI34546.1 - 0.00052 19.2 0.6 0.15 11.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KPI34546.1 - 0.00064 18.6 6.3 0.0007 18.5 3.4 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KPI34546.1 - 0.0016 17.5 0.4 0.0029 16.7 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KPI34546.1 - 0.0024 18.2 2.2 0.03 14.7 1.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI34546.1 - 0.0049 16.7 2.7 0.02 14.7 1.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI34546.1 - 0.012 15.6 0.5 0.037 14.0 0.3 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI34546.1 - 0.034 12.6 3.5 0.74 8.2 1.9 2.1 2 0 0 2 2 2 0 HI0933-like protein Big_3_3 PF13750.1 KPI34546.1 - 0.076 12.4 0.0 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Lycopene_cycl PF05834.7 KPI34546.1 - 0.15 10.9 0.9 0.85 8.4 0.6 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein ATG16 PF08614.6 KPI34547.1 - 0.00027 20.8 3.3 0.00036 20.4 1.5 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Atg14 PF10186.4 KPI34547.1 - 0.0062 15.5 0.6 0.011 14.6 0.4 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 CCDC144C PF14915.1 KPI34547.1 - 0.017 14.0 1.3 0.023 13.6 0.1 1.7 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region DivIC PF04977.10 KPI34547.1 - 2.3 7.7 7.0 10 5.7 0.3 3.3 3 1 0 3 3 3 0 Septum formation initiator Aldo_ket_red PF00248.16 KPI34548.1 - 3.3e-45 154.1 0.0 4.2e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_zinc_N PF00107.21 KPI34549.1 - 1.9e-24 85.6 0.1 3.2e-24 84.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI34549.1 - 2.6e-24 85.0 0.5 7e-24 83.6 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KPI34549.1 - 6.6e-06 27.0 0.0 1.6e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 KPI34549.1 - 0.054 13.9 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.16 KPI34549.1 - 0.1 12.1 1.3 15 5.0 0.8 2.4 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain WH1 PF00568.18 KPI34549.1 - 0.15 11.7 0.0 0.63 9.7 0.0 1.9 2 0 0 2 2 2 0 WH1 domain FBD PF08387.5 KPI34550.1 - 0.084 12.3 0.0 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 FBD Fungal_trans_2 PF11951.3 KPI34551.1 - 1.3e-06 27.3 0.4 0.00027 19.6 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 KPI34552.1 - 2.1e-16 60.6 0.0 8.8e-16 58.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI34552.1 - 1.3e-09 36.8 0.0 4e-08 31.9 0.0 2.6 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KPI34552.1 - 9.2e-07 28.0 0.0 5.1e-05 22.3 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KPI34552.1 - 4.8e-05 23.3 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 KPI34552.1 - 0.098 11.7 0.0 0.24 10.5 0.0 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cupin_2 PF07883.6 KPI34553.1 - 9.4e-19 66.6 0.3 3.6e-18 64.8 0.2 2.0 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.14 KPI34553.1 - 0.00031 20.4 0.0 0.00076 19.1 0.0 1.6 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 KPI34553.1 - 0.0076 15.6 0.3 0.048 13.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_1 PF00190.17 KPI34553.1 - 0.029 13.7 0.0 0.086 12.2 0.0 1.9 1 1 1 2 2 2 0 Cupin Auxin_BP PF02041.11 KPI34553.1 - 0.036 13.5 0.0 0.38 10.1 0.0 2.2 2 0 0 2 2 2 0 Auxin binding protein FAA_hydrolase PF01557.13 KPI34554.1 - 6.2e-57 192.5 0.0 8.3e-57 192.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family adh_short PF00106.20 KPI34555.1 - 3.2e-33 115.0 3.5 4e-33 114.6 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI34555.1 - 2e-25 89.9 0.7 2.3e-25 89.7 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI34555.1 - 1e-15 57.9 1.6 1.3e-15 57.5 1.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI34555.1 - 3.8e-08 33.0 0.4 5.5e-08 32.5 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KPI34555.1 - 0.0019 17.1 0.4 0.0023 16.8 0.3 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.9 KPI34555.1 - 0.0033 16.8 0.1 0.0067 15.8 0.1 1.5 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain THF_DHG_CYH_C PF02882.14 KPI34555.1 - 0.0045 16.0 0.3 0.033 13.2 0.0 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 KPI34555.1 - 0.0086 15.7 0.4 0.013 15.1 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KPI34555.1 - 0.012 15.6 1.1 0.076 13.0 0.8 2.0 1 1 0 1 1 1 0 NADH(P)-binding PAN_1 PF00024.21 KPI34556.1 - 6.1e-13 48.3 7.9 9.8e-06 25.2 0.2 3.4 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.1 KPI34556.1 - 2.1e-05 24.1 24.0 0.012 15.2 1.9 4.1 3 2 0 3 3 3 3 PAN domain SKG6 PF08693.5 KPI34556.1 - 0.02 14.2 0.1 0.049 12.9 0.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3042 PF11240.3 KPI34556.1 - 0.025 14.3 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) DUF4448 PF14610.1 KPI34556.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PAN_3 PF08277.7 KPI34556.1 - 0.45 10.1 7.0 7.5 6.2 0.1 3.5 3 0 0 3 3 3 0 PAN-like domain DUF1446 PF07287.6 KPI34557.1 - 3.5e-71 239.6 0.0 3.4e-36 124.4 0.2 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF1446) DLH PF01738.13 KPI34559.1 - 7.2e-08 31.9 0.0 8.6e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family RTA1 PF04479.8 KPI34559.1 - 0.055 12.9 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 RTA1 like protein Inhibitor_I34 PF10466.4 KPI34559.1 - 0.15 12.1 0.1 2 8.5 0.0 2.2 1 1 0 2 2 2 0 Saccharopepsin inhibitor I34 AA_permease_2 PF13520.1 KPI34560.1 - 1.2e-41 142.7 46.9 1.6e-41 142.2 32.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI34560.1 - 2.3e-20 72.4 39.8 3e-20 72.0 27.6 1.0 1 0 0 1 1 1 1 Amino acid permease MIP PF00230.15 KPI34561.1 - 5.1e-48 163.5 17.9 6.5e-48 163.1 12.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Cornifin PF02389.10 KPI34562.1 - 0.00057 19.7 0.9 0.00071 19.4 0.6 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family Mac PF12464.3 KPI34563.1 - 4e-19 68.3 0.0 6.9e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 KPI34563.1 - 2.3e-13 49.4 7.7 8.5e-11 41.2 1.7 3.3 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 KPI34563.1 - 2.6e-13 48.8 8.1 2.3e-11 42.6 2.6 3.2 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) rve_3 PF13683.1 KPI34563.1 - 0.033 13.6 0.2 0.058 12.9 0.1 1.3 1 0 0 1 1 1 0 Integrase core domain TauD PF02668.11 KPI34564.1 - 8e-40 137.1 0.2 1.1e-39 136.7 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 KPI34565.1 - 4.3e-29 101.3 18.7 4.3e-29 101.3 13.0 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily TMEM187 PF15100.1 KPI34565.1 - 0.0075 15.6 1.3 0.0091 15.4 0.2 1.6 2 0 0 2 2 2 1 TMEM187 protein family Zip PF02535.17 KPI34566.1 - 0.0029 16.6 1.5 0.0034 16.4 1.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter MmgE_PrpD PF03972.9 KPI34567.1 - 1.1e-125 419.3 0.1 8.5e-124 413.1 0.1 2.0 1 1 0 1 1 1 1 MmgE/PrpD family Zn_clus PF00172.13 KPI34568.1 - 1.6e-08 34.3 11.7 2.5e-08 33.7 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KPI34568.1 - 8.1e-08 31.2 0.0 1.5e-07 30.4 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain ApbA_C PF08546.6 KPI34569.1 - 3.4e-31 107.8 0.0 1.1e-30 106.2 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KPI34569.1 - 9.4e-28 96.5 0.0 1.3e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 KPI34569.1 - 0.0023 18.1 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding PRD PF00874.15 KPI34569.1 - 0.016 15.3 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 PRD domain NAD_binding_10 PF13460.1 KPI34569.1 - 0.057 13.4 0.0 0.16 11.9 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding Toxin_23 PF08093.6 KPI34569.1 - 1.9 8.4 3.7 5.2 7.0 0.3 2.2 2 0 0 2 2 2 0 Magi 5 toxic peptide family AMP-binding PF00501.23 KPI34570.1 - 5.3e-77 258.9 0.0 6.2e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI34570.1 - 6.7e-05 23.7 0.0 0.00022 22.0 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pyr_redox_3 PF13738.1 KPI34571.1 - 2.4e-23 83.2 0.0 3.9e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI34571.1 - 3.1e-12 45.4 0.0 5.9e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KPI34571.1 - 4e-10 39.1 0.0 1.1e-08 34.4 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KPI34571.1 - 6.3e-10 38.9 0.0 7.1e-09 35.5 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI34571.1 - 4.7e-08 33.1 0.0 1.9e-06 27.9 0.0 2.5 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI34571.1 - 3.9e-07 29.3 2.4 0.0022 16.9 0.2 3.0 3 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI34571.1 - 0.0025 16.7 0.0 0.0053 15.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KPI34571.1 - 0.0057 15.7 0.1 0.046 12.7 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 KPI34571.1 - 0.012 15.3 3.4 0.68 9.6 0.7 3.7 3 1 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KPI34571.1 - 0.043 12.7 0.8 0.14 11.0 0.1 2.1 2 1 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.15 KPI34571.1 - 0.11 12.5 0.1 16 5.6 0.0 2.8 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KPI34571.1 - 0.14 12.5 0.2 3.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI34571.1 - 0.38 9.1 1.1 3.3 6.0 0.0 2.3 3 0 0 3 3 3 0 HI0933-like protein Fungal_trans_2 PF11951.3 KPI34572.1 - 2.7e-06 26.2 0.3 3.7e-06 25.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain BROMI PF14961.1 KPI34572.1 - 0.046 10.8 0.0 0.057 10.5 0.0 1.1 1 0 0 1 1 1 0 Broad-minded protein TauD PF02668.11 KPI34574.1 - 1.3e-49 169.1 0.1 1.7e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Mg_trans_NIPA PF05653.9 KPI34575.1 - 2e-91 306.0 26.0 2.8e-91 305.6 18.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KPI34575.1 - 8.5e-08 32.3 2.2 8.5e-08 32.3 1.5 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KPI34575.1 - 3.9e-06 26.9 7.2 3.9e-06 26.9 5.0 2.9 3 1 0 3 3 3 1 EamA-like transporter family MFS_1 PF07690.11 KPI34576.1 - 9.2e-18 64.0 19.1 1.2e-17 63.7 13.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DAO PF01266.19 KPI34577.1 - 5.8e-43 147.1 0.0 6.7e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI34577.1 - 1.2e-08 34.7 0.0 4.2e-08 33.0 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KPI34577.1 - 1.4e-08 34.6 0.2 0.0042 16.8 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KPI34577.1 - 5.2e-06 26.4 0.0 0.0049 16.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI34577.1 - 3.5e-05 23.9 0.0 0.02 14.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI34577.1 - 0.0013 17.6 0.0 1 8.2 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 KPI34577.1 - 0.0081 14.6 0.0 0.021 13.3 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.9 KPI34577.1 - 0.015 13.9 0.0 0.61 8.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 KPI34577.1 - 0.022 13.6 0.1 0.15 10.8 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.19 KPI34577.1 - 0.024 13.7 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase K_oxygenase PF13434.1 KPI34577.1 - 0.047 12.6 0.0 3.8 6.3 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF4134 PF13572.1 KPI34577.1 - 0.076 13.1 0.6 0.19 11.8 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) Shikimate_DH PF01488.15 KPI34577.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 KPI34578.1 - 2.9e-64 217.3 24.8 1.3e-61 208.5 17.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI34578.1 - 1.5e-18 66.6 29.2 1.5e-18 66.6 20.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KPI34578.1 - 4.2e-07 28.7 15.9 5.4e-06 25.0 1.1 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein Ytp1 PF10355.4 KPI34579.1 - 3.8e-71 239.4 5.8 5.6e-71 238.9 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KPI34579.1 - 8.4e-24 83.1 0.5 8.4e-24 83.1 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF3237 PF11578.3 KPI34580.1 - 1.3e-38 131.6 0.0 1.9e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 KPI34580.1 - 2.7e-07 30.2 3.6 0.0077 15.9 0.1 2.3 2 0 0 2 2 2 2 BED zinc finger Herpes_capsid PF06112.6 KPI34580.1 - 0.02 14.9 0.5 0.07 13.1 0.1 1.9 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein zf-C2H2_2 PF12756.2 KPI34580.1 - 0.035 14.2 5.1 2.3 8.3 0.4 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PAT1 PF09770.4 KPI34580.1 - 8 4.5 7.0 9.9 4.2 4.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CorA PF01544.13 KPI34581.1 - 3.3e-39 134.6 0.2 1.1e-20 73.8 0.0 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein NAM-associated PF14303.1 KPI34581.1 - 0.23 11.7 6.4 0.25 11.6 2.3 2.5 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Zip PF02535.17 KPI34582.1 - 2.8e-33 115.2 0.2 3.4e-33 115.0 0.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter FSH1 PF03959.8 KPI34583.1 - 2.4e-44 151.3 0.0 3.4e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) MFS_1 PF07690.11 KPI34585.1 - 4.9e-14 51.8 34.2 1.6e-10 40.2 14.6 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily OATP PF03137.15 KPI34585.1 - 0.047 11.7 9.8 0.097 10.7 0.9 3.2 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3784 PF12650.2 KPI34585.1 - 0.062 13.2 0.3 0.062 13.2 0.2 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) Nt_Gln_amidase PF09764.4 KPI34586.1 - 0.094 11.9 0.1 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 N-terminal glutamine amidase p450 PF00067.17 KPI34587.1 - 4.7e-42 144.0 0.0 6.3e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 KPI34588.1 - 5.8e-69 232.4 0.0 7.1e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI34588.1 - 7.2e-09 36.4 0.0 1.6e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TMEM52 PF14979.1 KPI34588.1 - 0.039 13.8 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane 52 MFS_1 PF07690.11 KPI34589.1 - 1.3e-16 60.2 43.5 1.7e-16 59.8 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI34589.1 - 0.024 13.2 28.3 0.0047 15.5 13.2 2.6 1 1 1 2 2 2 0 Sugar (and other) transporter DUF1049 PF06305.6 KPI34589.1 - 3.2 7.2 11.5 1.5 8.3 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) Mpv17_PMP22 PF04117.7 KPI34590.1 - 5.6e-22 77.1 0.1 1.3e-21 75.9 0.1 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF3176 PF11374.3 KPI34593.1 - 1.3e-09 37.9 0.1 3.1e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) bZIP_1 PF00170.16 KPI34594.1 - 1.1e-06 28.4 10.8 1.1e-06 28.4 7.5 2.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KPI34594.1 - 0.00075 19.2 11.7 0.00075 19.2 8.1 3.8 3 1 1 4 4 4 1 Basic region leucine zipper bZIP_Maf PF03131.12 KPI34594.1 - 0.013 15.7 13.8 0.013 15.7 9.5 3.9 3 1 0 4 4 4 0 bZIP Maf transcription factor Fungal_trans PF04082.13 KPI34595.1 - 2.2e-15 56.2 0.2 3.7e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3176 PF11374.3 KPI34596.1 - 1.4e-07 31.3 4.2 1.8e-07 30.9 2.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF3808 PF10300.4 KPI34597.1 - 3.8e-131 437.8 0.0 5.7e-131 437.2 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) DSS1_SEM1 PF05160.8 KPI34599.1 - 4.9e-07 29.4 2.0 1.1e-05 25.1 0.1 2.2 2 0 0 2 2 2 2 DSS1/SEM1 family Bac_rhamnosid PF05592.6 KPI34600.1 - 2.7e-16 58.8 0.0 5.3e-15 54.6 0.0 2.5 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Chlam_vir PF05475.6 KPI34600.1 - 5.1 6.1 8.5 4 6.4 1.4 2.3 1 1 1 2 2 2 0 Chlamydia virulence protein PGP3-D FF PF01846.14 KPI34601.1 - 1.1e-51 172.5 21.7 3.7e-14 52.4 0.8 6.6 6 0 0 6 6 6 6 FF domain WW PF00397.21 KPI34601.1 - 8.1e-08 31.9 0.7 1.7e-07 30.9 0.5 1.6 1 0 0 1 1 1 1 WW domain F-box-like PF12937.2 KPI34602.1 - 5.1e-05 22.9 0.1 9.8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KPI34602.1 - 0.004 16.7 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain Glyco_trans_2_3 PF13632.1 KPI34603.1 - 3.2e-47 160.7 2.4 3.2e-47 160.7 1.7 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KPI34603.1 - 1.4e-09 38.0 0.1 2.2e-08 34.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KPI34603.1 - 6.2e-06 25.9 0.0 2.1e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KPI34603.1 - 4.5e-05 22.7 0.0 0.00092 18.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Sugar_tr PF00083.19 KPI34604.1 - 2.5e-105 352.6 20.4 2.8e-105 352.5 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI34604.1 - 2.1e-30 105.6 23.4 2.1e-30 105.6 16.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI34604.1 - 7.1e-09 34.5 14.2 4.3e-07 28.6 0.1 2.9 2 1 0 2 2 2 2 MFS/sugar transport protein ETRAMP PF09716.5 KPI34604.1 - 0.76 9.7 3.3 6.5 6.7 0.1 3.1 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) GtrA PF04138.9 KPI34604.1 - 5.3 7.0 15.8 0.14 12.1 4.5 3.1 3 2 1 4 4 4 0 GtrA-like protein Nup160 PF11715.3 KPI34605.1 - 7e-69 232.3 0.8 1.2e-68 231.5 0.6 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 MR_MLE_C PF13378.1 KPI34606.1 - 4.9e-18 65.1 0.0 1.6e-17 63.4 0.0 1.9 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KPI34606.1 - 9.3e-09 35.7 0.1 9.6e-08 32.4 0.0 2.4 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KPI34606.1 - 8.1e-06 25.8 0.0 6.1e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_16 PF00722.16 KPI34607.1 - 5.9e-21 74.5 0.3 3.7e-20 71.9 0.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Acetyltransf_1 PF00583.19 KPI34609.1 - 5.6e-14 51.9 0.0 7.6e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KPI34609.1 - 1.8e-07 31.2 0.0 2.1e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KPI34609.1 - 2.8e-07 30.6 0.0 3.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI34609.1 - 2.1e-05 24.6 0.0 2.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KPI34609.1 - 0.0007 19.4 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KPI34609.1 - 0.0068 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KPI34609.1 - 0.018 14.8 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain S1-P1_nuclease PF02265.11 KPI34611.1 - 6.4e-56 189.7 0.1 2.1e-55 188.0 0.1 1.7 1 1 0 1 1 1 1 S1/P1 Nuclease ELFV_dehydrog PF00208.16 KPI34612.1 - 5.9e-83 278.1 6.3 7.3e-83 277.8 4.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KPI34612.1 - 1.3e-45 154.1 0.0 4.3e-45 152.4 0.0 1.9 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Qn_am_d_aIV PF09100.5 KPI34612.1 - 0.03 14.0 0.3 0.14 11.8 0.1 2.1 1 1 1 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV AlaDh_PNT_C PF01262.16 KPI34612.1 - 0.051 13.1 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 KPI34612.1 - 0.11 12.7 0.1 0.28 11.4 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding PGK PF00162.14 KPI34613.1 - 6.1e-154 512.2 1.7 6.9e-154 512.0 1.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase TroA PF01297.12 KPI34613.1 - 0.044 13.0 0.4 1.2 8.3 0.0 2.5 3 0 0 3 3 3 0 Periplasmic solute binding protein family DUF1798 PF08807.5 KPI34614.1 - 0.016 14.9 0.1 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) NAD_binding_6 PF08030.7 KPI34617.1 - 7e-20 71.5 0.0 8.4e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KPI34617.1 - 0.076 13.5 0.0 0.11 13.0 0.0 1.3 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Sel1 PF08238.7 KPI34618.1 - 3.1e-17 62.6 4.8 1.7e-06 28.4 0.0 4.0 4 0 0 4 4 4 3 Sel1 repeat TPR_6 PF13174.1 KPI34618.1 - 0.15 12.5 2.4 8.8 7.0 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-CCCH PF00642.19 KPI34619.1 - 0.00061 19.4 13.0 0.00099 18.7 0.1 4.3 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1479 PF07350.7 KPI34620.1 - 5.9e-93 311.6 0.0 7.1e-93 311.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PKD_channel PF08016.7 KPI34620.1 - 0.14 10.5 0.0 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 Polycystin cation channel zf-MYND PF01753.13 KPI34621.1 - 4.4e-09 36.0 9.0 8.8e-09 35.0 6.3 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KPI34621.1 - 0.11 12.2 6.9 0.23 11.1 4.8 1.5 1 0 0 1 1 1 0 HIT zinc finger Ecl1 PF12855.2 KPI34621.1 - 0.48 9.7 4.9 1.1 8.6 3.4 1.5 1 0 0 1 1 1 0 Life-span regulatory factor Trs65 PF12735.2 KPI34623.1 - 8.3e-54 182.9 2.7 8.3e-54 182.9 1.9 1.9 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 Aldo_ket_red PF00248.16 KPI34624.1 - 3.5e-54 183.5 0.0 4.4e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TFIIF_beta PF02270.10 KPI34625.1 - 3.8e-51 174.5 1.9 4.6e-51 174.2 1.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Tau95 PF09734.4 KPI34625.1 - 0.0053 16.1 0.1 0.0063 15.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Aldolase_II PF00596.16 KPI34626.1 - 2.6e-39 134.7 0.0 3.2e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Spc24 PF08286.6 KPI34627.1 - 9.4e-29 99.5 0.0 4.2e-28 97.3 0.0 1.8 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 DUF3166 PF11365.3 KPI34627.1 - 0.016 15.6 0.2 0.03 14.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3166) DUF972 PF06156.8 KPI34627.1 - 0.029 14.7 2.0 0.066 13.5 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) SlyX PF04102.7 KPI34627.1 - 0.075 13.4 1.9 9.9 6.6 0.0 2.3 2 0 0 2 2 2 0 SlyX HAUS-augmin3 PF14932.1 KPI34627.1 - 0.11 11.6 1.4 0.14 11.3 1.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 GAS PF13851.1 KPI34627.1 - 0.17 11.0 2.2 0.2 10.8 0.6 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding MerR-DNA-bind PF09278.6 KPI34627.1 - 0.34 11.3 6.7 1.2 9.6 0.4 3.2 3 0 0 3 3 3 0 MerR, DNA binding Cep57_MT_bd PF06657.8 KPI34627.1 - 0.36 10.7 3.0 11 6.0 0.2 2.4 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Viral_P18 PF04521.8 KPI34627.1 - 1.3 8.5 3.9 1.3 8.4 0.1 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein MFS_1 PF07690.11 KPI34628.1 - 1.6e-29 102.7 38.6 2e-29 102.4 26.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily NfeD PF01957.13 KPI34628.1 - 0.064 13.3 0.1 0.064 13.3 0.1 3.7 5 0 0 5 5 5 0 NfeD-like C-terminal, partner-binding HbrB PF08539.6 KPI34629.1 - 1.5e-39 135.4 0.0 2.5e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 HbrB-like AJAP1_PANP_C PF15298.1 KPI34630.1 - 0.0066 16.3 0.2 0.0066 16.3 0.1 2.2 2 0 0 2 2 2 1 AJAP1/PANP C-terminus Epiglycanin_C PF14654.1 KPI34630.1 - 0.026 14.5 0.1 0.061 13.3 0.1 1.6 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region VSP PF03302.8 KPI34630.1 - 0.028 13.0 1.2 0.048 12.2 0.8 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein EphA2_TM PF14575.1 KPI34630.1 - 0.053 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 KPI34630.1 - 0.06 11.6 0.0 0.091 11.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 KPI34630.1 - 0.071 12.4 0.3 0.071 12.4 0.2 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain GMC_oxred_N PF00732.14 KPI34631.1 - 4.9e-59 199.9 0.0 7.5e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI34631.1 - 3.7e-27 95.3 0.0 8.3e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase MFS_1 PF07690.11 KPI34631.1 - 1.6e-25 89.6 39.4 2.8e-25 88.7 27.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KPI34631.1 - 3e-22 79.1 0.5 6.3e-20 71.5 0.2 2.6 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 KPI34631.1 - 2.7e-13 49.5 14.4 0.00017 20.6 0.1 4.1 3 1 1 4 4 4 3 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KPI34631.1 - 4.4e-12 45.5 0.5 1.1e-05 24.5 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 KPI34631.1 - 9.9e-10 38.3 3.2 0.00036 20.4 0.1 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI34631.1 - 1e-08 35.3 0.2 0.0017 18.2 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI34631.1 - 6.6e-08 31.8 6.0 0.0023 16.8 0.9 3.4 4 0 0 4 4 4 2 FAD binding domain Pyr_redox PF00070.22 KPI34631.1 - 1.9e-07 31.4 1.0 0.12 12.8 0.1 3.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI34631.1 - 2.3e-07 29.6 5.2 0.07 11.5 0.6 4.0 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.12 KPI34631.1 - 4.6e-05 22.6 1.1 0.08 12.0 0.0 2.7 3 0 0 3 3 3 2 Thi4 family Pyr_redox_3 PF13738.1 KPI34631.1 - 0.00018 21.6 1.2 1.2 9.1 0.0 3.9 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KPI34631.1 - 0.046 12.8 3.4 0.17 10.9 0.0 2.8 4 0 0 4 4 4 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 KPI34631.1 - 0.37 9.3 2.2 3 6.3 0.0 2.7 2 1 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KPI34631.1 - 1.5 8.6 4.2 18 5.0 0.3 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 KPI34631.1 - 5.8 5.6 6.6 11 4.7 2.3 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KPI34632.1 - 3.2e-28 99.0 0.1 4.7e-28 98.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI34632.1 - 4.3e-16 59.0 0.3 4.9e-14 52.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI34632.1 - 1.2e-09 38.5 0.2 9.6e-06 25.7 0.0 3.2 1 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KPI34632.1 - 1.9e-05 24.8 0.1 0.0029 17.8 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 KPI34632.1 - 7.8e-05 21.8 0.2 0.0014 17.7 0.0 2.4 2 1 1 3 3 3 1 Thi4 family K_oxygenase PF13434.1 KPI34632.1 - 0.00015 20.7 0.1 0.15 10.9 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KPI34632.1 - 0.00023 20.2 5.9 0.59 8.9 0.2 3.5 2 2 1 4 4 4 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI34632.1 - 0.00045 20.1 0.6 0.043 13.8 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KPI34632.1 - 0.0047 16.0 0.6 0.49 9.4 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KPI34632.1 - 0.022 13.8 1.2 4 6.3 0.0 3.0 2 1 1 3 3 3 0 FAD binding domain GIDA PF01134.17 KPI34632.1 - 0.029 13.2 5.6 3.6 6.3 0.1 4.1 4 1 1 5 5 5 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 KPI34632.1 - 0.03 14.4 0.3 6.8 6.7 0.0 2.6 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 KPI34632.1 - 0.038 12.8 8.0 1.5 7.5 0.2 4.0 2 2 3 5 5 5 0 FAD binding domain IlvN PF07991.7 KPI34632.1 - 0.11 11.8 0.0 2.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_9 PF13454.1 KPI34632.1 - 0.12 12.1 0.1 41 3.9 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Calreticulin PF00262.13 KPI34633.1 - 2.3e-162 539.7 16.2 3e-162 539.4 11.2 1.1 1 0 0 1 1 1 1 Calreticulin family IL13 PF03487.8 KPI34633.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Interleukin-13 DUF615 PF04751.9 KPI34633.1 - 0.27 10.8 3.8 1 9.0 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF615) DAO PF01266.19 KPI34634.1 - 3.8e-51 174.1 0.7 4.3e-51 173.9 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI34634.1 - 4.2e-08 33.1 0.5 8.8e-07 28.8 0.0 2.7 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI34634.1 - 8.3e-07 28.1 2.0 6.4e-06 25.2 1.4 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KPI34634.1 - 0.00012 22.0 0.1 0.012 15.5 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI34634.1 - 0.00069 18.5 0.0 0.58 8.9 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KPI34634.1 - 0.0019 18.3 0.0 0.051 13.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KPI34634.1 - 0.0021 18.1 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KPI34634.1 - 0.0023 17.9 0.0 0.0064 16.4 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain GMC_oxred_N PF00732.14 KPI34634.1 - 0.0027 16.9 0.6 0.69 9.0 0.0 2.6 2 1 1 3 3 3 2 GMC oxidoreductase Pyr_redox PF00070.22 KPI34634.1 - 0.004 17.5 0.0 0.012 16.0 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI34634.1 - 0.0089 15.8 0.0 0.82 9.4 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KPI34634.1 - 0.016 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.16 KPI34634.1 - 0.016 15.0 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 ThiF family adh_short PF00106.20 KPI34634.1 - 0.076 12.9 0.3 0.13 12.1 0.0 1.6 2 0 0 2 2 1 0 short chain dehydrogenase ApbA PF02558.11 KPI34634.1 - 0.15 11.4 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 KPI34634.1 - 0.15 10.9 0.1 0.68 8.8 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase HEM4 PF02602.10 KPI34635.1 - 1.3e-27 96.5 0.0 2.3e-13 49.9 0.0 2.4 1 1 1 2 2 2 2 Uroporphyrinogen-III synthase HemD HAD_2 PF13419.1 KPI34636.1 - 7.1e-10 39.3 0.0 0.00043 20.5 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KPI34636.1 - 0.0076 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like MFS_1 PF07690.11 KPI34637.1 - 1.1e-15 57.2 36.4 4.7e-15 55.1 15.9 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Aldedh PF00171.17 KPI34638.1 - 9e-135 449.5 0.2 1.2e-134 449.1 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GTP_cyclohydro2 PF00925.15 KPI34638.1 - 0.032 13.4 0.0 0.064 12.4 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase II LuxC PF05893.9 KPI34638.1 - 0.061 12.0 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF3425 PF11905.3 KPI34639.1 - 4.3e-17 62.2 2.5 1.2e-16 60.8 1.7 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KPI34639.1 - 0.0013 18.6 3.6 0.0021 17.9 2.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KPI34639.1 - 0.031 14.0 2.2 0.055 13.3 1.5 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DUF4164 PF13747.1 KPI34640.1 - 0.029 14.5 10.3 9.4 6.4 1.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) End3 PF12761.2 KPI34640.1 - 0.032 13.8 0.8 0.044 13.4 0.1 1.5 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Myosin_tail_1 PF01576.14 KPI34640.1 - 0.068 10.8 4.8 0.11 10.2 3.3 1.2 1 0 0 1 1 1 0 Myosin tail BLOC1_2 PF10046.4 KPI34640.1 - 0.12 12.5 1.7 14 5.8 0.1 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tektin PF03148.9 KPI34640.1 - 0.21 10.0 3.3 0.11 11.0 0.1 2.0 3 0 0 3 3 3 0 Tektin family Seryl_tRNA_N PF02403.17 KPI34640.1 - 0.3 11.1 4.5 1.2 9.1 1.2 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.1 KPI34640.1 - 0.69 9.8 3.3 1.8 8.5 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.4 KPI34640.1 - 0.82 9.5 4.8 6.2 6.6 3.2 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 KPI34640.1 - 0.95 9.3 6.8 6.6 6.5 4.7 2.0 1 1 0 1 1 1 0 Tropomyosin like Gon7 PF08738.5 KPI34644.1 - 2.7e-05 24.1 13.9 0.00031 20.6 3.6 2.1 1 1 1 2 2 2 2 Gon7 family KGG PF10685.4 KPI34644.1 - 0.13 12.1 1.3 0.29 11.1 0.9 1.6 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif MFS_1 PF07690.11 KPI34645.1 - 3.5e-30 104.9 25.1 3.5e-30 104.9 17.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TFIIA PF03153.8 KPI34646.1 - 3.2 7.5 20.5 3.7 7.3 14.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HSP20 PF00011.16 KPI34647.1 - 1.9e-20 72.6 1.4 4.8e-14 52.0 0.1 2.1 1 1 1 2 2 2 2 Hsp20/alpha crystallin family LRR_4 PF12799.2 KPI34648.1 - 7.4e-16 57.3 6.3 0.17 11.5 0.0 7.1 5 2 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KPI34648.1 - 3.8e-11 42.5 16.4 0.00034 20.3 0.7 6.4 4 2 3 7 7 7 6 Leucine rich repeat F-box-like PF12937.2 KPI34648.1 - 7.8e-11 41.5 1.4 1.5e-10 40.6 0.3 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KPI34648.1 - 5.5e-05 22.7 0.0 0.00021 20.8 0.0 2.1 1 0 0 1 1 1 1 F-box domain Recep_L_domain PF01030.19 KPI34648.1 - 0.014 15.3 0.2 8.9 6.3 0.0 3.9 2 1 1 3 3 3 0 Receptor L domain STAS_2 PF13466.1 KPI34648.1 - 8.2 6.5 11.3 0.13 12.2 0.3 3.5 4 1 1 5 5 5 0 STAS domain AA_permease_2 PF13520.1 KPI34649.1 - 1.2e-60 205.3 57.6 1.4e-60 205.0 39.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI34649.1 - 2.6e-14 52.4 49.3 3.3e-14 52.1 34.2 1.1 1 0 0 1 1 1 1 Amino acid permease NMO PF03060.10 KPI34650.1 - 2.9e-70 237.0 1.2 3.6e-70 236.7 0.9 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KPI34650.1 - 2.4e-08 33.2 0.1 1.7e-05 23.9 0.0 3.0 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KPI34650.1 - 1.4e-05 24.1 1.4 1.4e-05 24.1 1.0 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KPI34650.1 - 0.00033 19.6 0.1 0.00059 18.8 0.1 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 KPI34650.1 - 0.01 14.8 0.3 0.018 13.9 0.2 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Catalase PF00199.14 KPI34651.1 - 9.8e-157 521.5 0.1 1.3e-156 521.1 0.1 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KPI34651.1 - 1.1e-15 57.1 0.0 2.6e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 KPI34651.1 - 0.00047 19.6 0.1 0.0011 18.3 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family HbrB PF08539.6 KPI34653.1 - 5.2e-05 23.1 0.2 9.1e-05 22.3 0.1 1.5 2 0 0 2 2 2 1 HbrB-like AA_permease PF00324.16 KPI34654.1 - 3.6e-73 246.5 43.2 9e-70 235.3 29.9 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI34654.1 - 1.6e-19 69.7 42.1 1.2e-17 63.5 21.5 2.0 1 1 1 2 2 2 2 Amino acid permease PrgI PF12666.2 KPI34654.1 - 0.45 10.6 0.1 0.45 10.6 0.0 4.1 4 2 0 5 5 5 0 PrgI family protein Zn_clus PF00172.13 KPI34655.1 - 4.2e-07 29.7 6.8 8.9e-07 28.7 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KPI34656.1 - 1.3e-19 70.7 1.9 4.7e-19 68.8 1.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI34656.1 - 0.00012 21.7 0.1 0.00058 19.5 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KPI34656.1 - 0.0002 21.2 0.0 0.001 18.8 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KPI34656.1 - 0.0032 16.9 0.0 0.051 13.0 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Vps39_1 PF10366.4 KPI34657.1 - 1.5e-32 111.7 0.4 1.5e-29 102.1 0.0 3.1 3 0 0 3 3 3 2 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KPI34657.1 - 4.1e-31 107.3 0.0 2.2e-30 105.0 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 KPI34657.1 - 7.5e-19 68.1 0.0 1.7e-18 67.0 0.0 1.5 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 KPI34657.1 - 1.1e-08 34.7 8.8 1.5e-07 31.1 2.3 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS TPR_1 PF00515.23 KPI34657.1 - 0.05 13.2 1.1 1.1 8.9 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KPI34657.1 - 0.1 13.2 1.0 1.2e+02 3.8 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KPI34657.1 - 0.13 12.5 4.2 5 7.5 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 KPI34657.1 - 4.9 6.8 6.7 0.78 9.4 0.1 3.1 5 0 0 5 5 5 0 TPR repeat Abhydrolase_4 PF08386.5 KPI34658.1 - 2.6e-22 78.6 0.0 5.5e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KPI34658.1 - 8.4e-15 54.9 0.1 8.1e-14 51.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI34658.1 - 1.5e-06 28.3 0.0 9e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KPI34658.1 - 0.067 12.6 0.0 0.15 11.5 0.0 1.5 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Fis1_TPR_C PF14853.1 KPI34659.1 - 4.7e-27 93.6 1.6 6.9e-27 93.0 1.1 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KPI34659.1 - 4e-17 61.2 0.0 6.2e-17 60.5 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 KPI34659.1 - 0.0018 18.0 2.4 0.0018 18.0 1.7 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KPI34659.1 - 0.0074 16.9 0.2 0.012 16.2 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 KPI34659.1 - 0.051 14.0 0.3 0.12 12.9 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 KPI34659.1 - 0.22 11.8 1.4 0.26 11.6 0.3 1.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.8 KPI34660.1 - 2.3e-35 122.0 0.0 1.1e-25 90.5 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold zf-RING_2 PF13639.1 KPI34660.1 - 1.1e-13 50.7 7.9 1.1e-13 50.7 5.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KPI34660.1 - 3.3e-09 36.2 10.5 8.4e-09 34.9 3.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI34660.1 - 1.3e-06 28.3 7.2 1.3e-06 28.3 5.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI34660.1 - 1.4e-06 27.7 7.2 1.4e-06 27.7 5.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KPI34660.1 - 2.6e-06 27.4 3.4 2.6e-06 27.4 2.4 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KPI34660.1 - 0.00019 21.1 5.7 0.00019 21.1 3.9 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_3 PF14369.1 KPI34660.1 - 0.00023 21.1 4.2 0.00023 21.1 2.9 3.1 3 0 0 3 3 3 1 zinc-finger zf-Apc11 PF12861.2 KPI34660.1 - 0.0026 17.5 3.0 0.0069 16.1 2.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.14 KPI34660.1 - 0.0069 16.0 0.6 0.0069 16.0 0.4 2.9 4 0 0 4 4 3 1 Hydrogenase expression/synthesis hypA family TF_Zn_Ribbon PF08271.7 KPI34660.1 - 0.0083 15.4 0.6 0.022 14.0 0.4 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Baculo_RING PF05883.6 KPI34660.1 - 0.03 14.1 3.0 0.2 11.4 0.5 2.3 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain FANCL_C PF11793.3 KPI34660.1 - 0.071 13.0 7.8 0.78 9.7 5.4 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 KPI34660.1 - 0.16 11.8 10.2 3 7.8 0.1 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF2424 PF10340.4 KPI34660.1 - 0.23 10.0 0.0 0.36 9.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Trm112p PF03966.11 KPI34660.1 - 0.4 11.0 1.7 5.1 7.5 0.1 3.1 3 0 0 3 3 3 0 Trm112p-like protein DZR PF12773.2 KPI34660.1 - 1.9 8.3 7.4 5.2 6.9 0.3 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.1 KPI34660.1 - 2.2 7.9 12.9 0.31 10.6 2.4 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.24 KPI34660.1 - 2.9 7.6 14.4 0.55 9.9 4.9 2.5 2 0 0 2 2 2 0 PHD-finger zinc-ribbons_6 PF07191.7 KPI34660.1 - 8.5 6.2 8.2 3.7 7.3 0.1 2.7 2 1 1 3 3 3 0 zinc-ribbons Abhydrolase_6 PF12697.2 KPI34661.1 - 1.6e-23 83.7 0.2 2.1e-23 83.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI34661.1 - 3.2e-11 43.2 0.0 1.5e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI34661.1 - 8.7e-08 32.0 0.0 1.6e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KPI34661.1 - 0.0016 17.7 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KPI34661.1 - 0.0038 17.0 0.0 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KPI34661.1 - 0.0061 15.8 0.0 0.0086 15.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DGF-1_4 PF11024.3 KPI34662.1 - 0.31 11.4 3.9 9.5 6.6 0.2 2.8 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 S4 PF01479.20 KPI34663.1 - 2.5e-16 58.8 0.0 4.5e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 KPI34663.1 - 0.025 14.1 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 S4 domain SOBP PF15279.1 KPI34663.1 - 0.077 13.3 2.6 0.13 12.6 1.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein K_trans PF02705.11 KPI34664.1 - 1.3e-171 571.6 18.3 1.7e-171 571.2 12.7 1.1 1 0 0 1 1 1 1 K+ potassium transporter FAD_binding_3 PF01494.14 KPI34665.1 - 5.6e-18 65.1 0.0 1.9e-09 37.0 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 KPI34665.1 - 0.2 10.0 0.2 0.82 8.0 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein HATPase_c PF02518.21 KPI34667.1 - 8.3e-19 67.3 0.1 1.7e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KPI34667.1 - 5.5e-15 55.3 0.1 1.7e-10 40.8 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 KPI34667.1 - 5.1e-13 48.8 0.0 2.9e-12 46.3 0.0 2.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 KPI34667.1 - 0.0049 16.9 0.0 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 GAF domain Sugar_tr PF00083.19 KPI34668.1 - 8e-111 370.7 30.7 1.9e-110 369.5 21.3 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI34668.1 - 5.8e-24 84.4 56.8 1.7e-14 53.2 17.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI34668.1 - 0.31 9.4 44.6 0.13 10.6 10.5 3.8 2 2 1 3 3 3 0 MFS/sugar transport protein p450 PF00067.17 KPI34669.1 - 1.4e-61 208.4 0.0 1.8e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF377 PF04041.8 KPI34670.1 - 6.8e-39 133.4 0.0 9.4e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF377) Glyco_hydro_32N PF00251.15 KPI34670.1 - 4.2e-07 29.6 0.0 4e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.9 KPI34670.1 - 0.0015 17.7 0.5 0.021 13.9 0.1 2.6 2 1 1 3 3 3 1 Glycosyl hydrolases family 43 BNR_3 PF13859.1 KPI34670.1 - 0.056 12.4 0.7 0.25 10.3 0.3 1.9 1 1 1 2 2 2 0 BNR repeat-like domain TRI12 PF06609.8 KPI34672.1 - 1.1e-47 162.5 22.7 1.5e-47 162.1 15.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI34672.1 - 1.1e-25 90.1 43.7 1.1e-25 90.1 30.3 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI34672.1 - 1.9e-08 33.3 16.9 1.9e-08 33.3 11.7 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter Oxidored_FMN PF00724.15 KPI34673.1 - 2.4e-20 72.8 0.0 2.7e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PAN_4 PF14295.1 KPI34674.1 - 0.0074 15.9 1.2 0.014 15.1 0.8 1.5 1 0 0 1 1 1 1 PAN domain SprB PF13573.1 KPI34674.1 - 0.95 9.1 6.6 0.43 10.2 1.7 2.5 2 0 0 2 2 2 0 SprB repeat EthD PF07110.6 KPI34675.1 - 1.2e-07 32.5 0.0 1.4e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 EthD domain p450 PF00067.17 KPI34676.1 - 3.3e-65 220.4 0.0 4.1e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Orbi_VP1 PF05788.7 KPI34676.1 - 0.094 9.9 0.0 0.13 9.4 0.0 1.0 1 0 0 1 1 1 0 Orbivirus RNA-dependent RNA polymerase (VP1) Aldo_ket_red PF00248.16 KPI34678.1 - 2.8e-54 183.8 0.0 3.3e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family IF2_N PF04760.10 KPI34678.1 - 0.038 13.6 0.1 0.47 10.1 0.0 2.6 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Slx4 PF09494.5 KPI34678.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Slx4 endonuclease PAN_1 PF00024.21 KPI34679.1 - 1e-07 31.5 0.1 0.0067 16.1 0.0 2.2 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.1 KPI34679.1 - 0.0082 15.8 5.1 0.12 12.0 0.1 2.6 2 1 0 2 2 2 2 PAN domain TrkH PF02386.11 KPI34680.1 - 2.3e-86 289.6 4.8 1.3e-80 270.6 0.4 2.1 2 0 0 2 2 2 2 Cation transport protein Fungal_trans_2 PF11951.3 KPI34681.1 - 2.3e-07 29.7 1.4 0.0058 15.2 0.5 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 KPI34682.1 - 5.3e-18 65.2 0.0 2.1e-10 40.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KPI34682.1 - 8.3e-08 31.5 0.1 2.3e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI34682.1 - 2e-05 24.4 0.1 5.7e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KPI34682.1 - 0.0015 18.8 0.1 0.0035 17.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KPI34682.1 - 0.003 17.2 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KPI34682.1 - 0.0039 17.1 0.6 0.008 16.0 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI34682.1 - 0.0049 15.7 0.1 0.0074 15.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_10 PF13460.1 KPI34682.1 - 0.013 15.4 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding TrkA_N PF02254.13 KPI34682.1 - 0.018 15.0 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 KPI34682.1 - 0.022 15.1 0.1 0.053 13.9 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.1 KPI34682.1 - 0.027 14.2 0.1 0.17 11.6 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KPI34682.1 - 0.043 12.7 0.1 0.64 8.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 KPI34682.1 - 0.054 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 KPI34682.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 KPI34682.1 - 0.069 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 KPI34682.1 - 0.082 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 KPI34682.1 - 0.15 10.5 0.1 0.31 9.4 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 KPI34682.1 - 0.2 10.4 0.1 0.56 9.0 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Chromo PF00385.19 KPI34683.1 - 8.9e-05 22.0 1.6 0.00022 20.8 1.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_S15 PF02129.13 KPI34684.1 - 1.7e-43 149.0 1.2 3.8e-40 138.0 0.2 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KPI34684.1 - 2.1e-28 99.7 0.3 3e-28 99.2 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KPI34684.1 - 3e-05 24.0 0.1 5.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI34684.1 - 0.002 17.8 0.1 0.0051 16.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI34684.1 - 0.0033 16.6 0.1 0.0055 15.9 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PP2C PF00481.16 KPI34685.1 - 1.6e-36 126.0 0.1 6.4e-31 107.6 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Fungal_trans PF04082.13 KPI34688.1 - 4.6e-12 45.3 0.1 8.1e-12 44.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CDP-OH_P_transf PF01066.16 KPI34689.1 - 3.2e-19 69.1 2.2 3.2e-19 69.1 1.5 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ADH_zinc_N PF00107.21 KPI34690.1 - 1.1e-08 34.6 0.2 2.3e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI34690.1 - 8e-07 28.7 0.1 1.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Oxidored_FMN PF00724.15 KPI34691.1 - 9.2e-31 107.0 0.0 2e-23 82.9 0.0 2.2 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.13 KPI34691.1 - 7.4e-17 61.0 0.3 1.1e-16 60.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain His_Phos_1 PF00300.17 KPI34693.1 - 1.7e-17 63.9 0.0 2.3e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RFPL3_antisense PF10489.4 KPI34693.1 - 0.03 14.0 0.0 0.081 12.7 0.0 1.7 2 0 0 2 2 2 0 Ret finger protein-like 3 antisense Biotin_carb_C PF02785.14 KPI34696.1 - 1.4e-36 124.6 0.0 3.2e-36 123.5 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_D2 PF02786.12 KPI34696.1 - 8.3e-16 57.9 0.0 1.8e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_lipoyl PF00364.17 KPI34696.1 - 7.4e-14 51.1 0.5 3.1e-13 49.1 0.2 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KPI34696.1 - 3.9e-05 23.2 0.7 0.0083 15.7 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD PF00529.15 KPI34696.1 - 0.00013 21.3 1.7 0.025 13.9 0.0 2.7 3 0 0 3 3 3 2 HlyD family secretion protein RnfC_N PF13375.1 KPI34696.1 - 0.00034 20.2 0.0 0.001 18.7 0.0 1.9 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_2 PF12700.2 KPI34696.1 - 0.00073 18.7 0.0 0.0085 15.2 0.0 2.0 1 1 1 2 2 2 1 HlyD family secretion protein DUF2118 PF09891.4 KPI34696.1 - 0.12 12.1 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) bZIP_1 PF00170.16 KPI34697.1 - 4.3e-06 26.5 16.7 6.2e-06 26.0 11.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor FH2 PF02181.18 KPI34697.1 - 0.0029 16.5 0.5 0.0036 16.2 0.3 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Glutaredoxin2_C PF04399.8 KPI34697.1 - 0.0075 15.8 0.8 0.013 15.0 0.5 1.3 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GAS PF13851.1 KPI34697.1 - 0.16 11.1 7.4 0.23 10.6 5.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding bZIP_Maf PF03131.12 KPI34697.1 - 0.26 11.6 13.5 0.53 10.6 9.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor IncA PF04156.9 KPI34697.1 - 0.45 10.0 3.7 0.71 9.4 2.6 1.3 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 KPI34697.1 - 0.81 9.5 17.8 1.6 8.6 12.4 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Fib_alpha PF08702.5 KPI34697.1 - 1.5 8.9 5.4 3.1 7.9 3.7 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Bap31 PF05529.7 KPI34697.1 - 1.8 7.9 6.6 2.6 7.4 4.6 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like PdxA PF04166.7 KPI34698.1 - 1.3e-78 264.3 0.0 1.6e-78 263.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Septin PF00735.13 KPI34699.1 - 1.9e-121 404.4 0.1 1.9e-121 404.4 0.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KPI34699.1 - 2.9e-07 30.4 0.0 6.1e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KPI34699.1 - 6e-05 22.2 0.3 0.00053 19.2 0.2 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 KPI34699.1 - 0.00012 22.3 3.3 0.02 15.1 0.0 2.8 3 0 0 3 3 3 1 ABC transporter GTP_EFTU PF00009.22 KPI34699.1 - 0.00017 21.1 1.4 0.0036 16.7 0.0 2.9 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KPI34699.1 - 0.00024 20.6 1.5 0.0015 18.0 0.6 2.4 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 KPI34699.1 - 0.0014 18.6 0.1 0.014 15.3 0.0 2.5 3 0 0 3 3 2 1 AAA ATPase domain AIG1 PF04548.11 KPI34699.1 - 0.0023 17.0 1.7 0.0031 16.6 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 KPI34699.1 - 0.0028 18.1 0.3 0.012 16.1 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 KPI34699.1 - 0.005 16.9 0.0 0.03 14.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KPI34699.1 - 0.0069 16.2 7.9 0.52 10.1 0.0 3.5 3 1 0 3 3 3 1 Dynamin family ATP_bind_1 PF03029.12 KPI34699.1 - 0.0071 15.9 0.1 1.4 8.4 0.0 3.0 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein Ras PF00071.17 KPI34699.1 - 0.0092 15.3 0.1 0.039 13.3 0.0 2.1 2 1 0 2 2 1 1 Ras family AAA_29 PF13555.1 KPI34699.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KPI34699.1 - 0.017 14.5 1.0 0.024 14.0 0.0 1.7 2 0 0 2 2 1 0 FtsK/SpoIIIE family Exonuc_VII_L PF02601.10 KPI34699.1 - 0.059 12.5 7.4 0.12 11.5 5.1 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_24 PF13479.1 KPI34699.1 - 0.073 12.6 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain YlqD PF11068.3 KPI34699.1 - 0.089 12.8 11.7 0.19 11.7 8.1 1.5 1 0 0 1 1 1 0 YlqD protein RNA_helicase PF00910.17 KPI34699.1 - 0.091 12.9 1.3 0.7 10.0 0.0 2.6 3 0 0 3 3 2 0 RNA helicase DUF2937 PF11157.3 KPI34699.1 - 0.12 11.6 4.0 0.27 10.5 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) MobB PF03205.9 KPI34699.1 - 0.16 11.7 1.3 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Phage_GPO PF05929.6 KPI34699.1 - 0.24 10.6 7.1 0.38 9.9 4.9 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase AAA_32 PF13654.1 KPI34699.1 - 0.36 9.4 13.0 0.53 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KPI34699.1 - 0.82 9.4 4.3 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 V_ATPase_I PF01496.14 KPI34699.1 - 5.9 4.6 11.9 8.7 4.0 8.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MBOAT_2 PF13813.1 KPI34700.1 - 6.7e-14 51.7 0.8 6.7e-14 51.7 0.6 2.1 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Asp PF00026.18 KPI34701.1 - 5.8e-09 35.6 0.0 1.4e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Syndecan PF01034.15 KPI34701.1 - 0.079 12.6 0.3 0.079 12.6 0.2 1.6 2 0 0 2 2 2 0 Syndecan domain EphA2_TM PF14575.1 KPI34701.1 - 0.089 13.1 0.0 0.22 11.9 0.0 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2242 PF10001.4 KPI34701.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2242) Gly-zipper_YMGG PF13441.1 KPI34701.1 - 2.2 7.8 9.7 4.4 6.8 6.7 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Dabb PF07876.7 KPI34702.1 - 1.5e-24 86.2 0.0 1.7e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ribosomal_S7 PF00177.16 KPI34703.1 - 2.9e-24 85.3 0.2 7.4e-24 84.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e MFS_1 PF07690.11 KPI34704.1 - 5.7e-39 133.8 31.9 7.9e-39 133.3 22.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UDPG_MGDP_dh_N PF03721.9 KPI34705.1 - 1.1e-53 181.4 0.0 1.8e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 KPI34705.1 - 1.1e-30 105.7 0.1 2.3e-30 104.6 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 KPI34705.1 - 3.5e-18 65.6 1.4 1.3e-13 51.0 0.1 4.3 3 1 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 3HCDH_N PF02737.13 KPI34705.1 - 0.0052 16.4 0.0 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 KPI34705.1 - 0.025 14.4 0.1 2.5 7.9 0.0 2.9 3 0 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KPI34705.1 - 0.042 12.8 0.0 0.069 12.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 KPI34705.1 - 0.058 13.1 0.7 0.48 10.1 0.1 2.8 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CLN3 PF02487.12 KPI34706.1 - 4.8e-96 321.9 8.3 8.4e-94 314.6 5.8 2.2 1 1 0 1 1 1 1 CLN3 protein Fungal_trans PF04082.13 KPI34707.1 - 1.2e-08 34.1 0.4 2.1e-08 33.3 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI34707.1 - 4e-05 23.4 8.8 7e-05 22.6 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1325 PF07039.6 KPI34708.1 - 3e-17 62.4 0.1 4.9e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF2560 PF10834.3 KPI34708.1 - 0.018 15.0 1.5 0.034 14.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2560) DUF1989 PF09347.5 KPI34709.1 - 2e-50 170.4 0.0 3.5e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) AAA PF00004.24 KPI34709.1 - 9.3e-13 48.5 0.0 3e-12 46.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SET PF00856.23 KPI34709.1 - 8.1e-09 35.9 0.2 5.1e-08 33.3 0.0 2.3 2 0 0 2 2 2 1 SET domain BCS1_N PF08740.6 KPI34709.1 - 8.4e-07 28.7 0.4 5.1e-06 26.2 0.2 2.4 2 1 0 2 2 2 1 BCS1 N terminal AAA_17 PF13207.1 KPI34709.1 - 0.013 16.2 0.0 0.037 14.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KPI34709.1 - 0.017 13.8 0.0 0.036 12.8 0.0 1.4 1 1 0 1 1 1 0 TIP49 C-terminus AAA_33 PF13671.1 KPI34709.1 - 0.044 13.6 0.2 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KPI34709.1 - 0.087 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus SelP_N PF04592.9 KPI34709.1 - 0.089 12.1 1.3 0.18 11.1 0.9 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region AAA_5 PF07728.9 KPI34709.1 - 0.19 11.4 0.0 0.77 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ADH_N PF08240.7 KPI34710.1 - 3.7e-07 29.8 0.0 7.4e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI34710.1 - 2.1e-06 27.3 0.2 1.6e-05 24.4 0.1 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI34710.1 - 9.2e-05 23.3 0.1 0.00021 22.1 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-oxoacid_dh PF00198.18 KPI34711.1 - 4.8e-75 251.7 0.1 6e-75 251.4 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KPI34711.1 - 5.5e-17 61.1 0.9 1.2e-16 60.0 0.6 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Mito_carr PF00153.22 KPI34713.1 - 1.5e-59 197.6 2.4 1.9e-19 69.1 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein L51_S25_CI-B8 PF05047.11 KPI34715.1 - 1.1e-05 25.0 0.1 2.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Sec7_N PF12783.2 KPI34716.1 - 3.5e-49 166.4 3.7 3.5e-49 166.4 2.5 2.9 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec7 PF01369.15 KPI34716.1 - 4.6e-40 137.3 6.9 2.7e-37 128.2 0.4 4.4 4 1 0 4 4 4 1 Sec7 domain DUF1981 PF09324.5 KPI34716.1 - 4e-32 109.5 4.9 1.6e-31 107.6 0.1 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) BING4CT PF08149.6 KPI34717.1 - 8.1e-40 134.2 0.0 1.7e-36 123.5 0.0 2.8 2 0 0 2 2 2 2 BING4CT (NUC141) domain WD40 PF00400.27 KPI34717.1 - 2.7e-05 23.8 0.0 0.018 14.9 0.0 3.8 3 1 0 3 3 3 1 WD domain, G-beta repeat DUF2046 PF09755.4 KPI34718.1 - 0.063 12.1 1.3 0.4 9.5 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) Pox_A_type_inc PF04508.7 KPI34718.1 - 0.076 12.8 0.2 0.26 11.1 0.1 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Med15_fungi PF05397.7 KPI34718.1 - 0.63 10.0 2.8 0.34 10.8 0.3 1.6 2 0 0 2 2 2 0 Mediator complex subunit 15 Fe-S_biosyn PF01521.15 KPI34719.1 - 2.6e-19 69.1 0.0 3.4e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis PAT1 PF09770.4 KPI34719.1 - 3.8 5.6 12.7 4.6 5.3 8.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 KPI34719.1 - 8.4 6.1 7.8 9.9 5.9 5.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pribosyltran_N PF13793.1 KPI34720.1 - 1.2e-42 144.2 0.1 1e-41 141.2 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KPI34720.1 - 1.6e-31 109.4 0.8 1.2e-27 96.8 0.1 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KPI34720.1 - 0.00011 21.9 0.7 0.013 15.2 0.1 2.7 2 1 0 2 2 2 2 Phosphoribosyl transferase domain GTP_cyclohydro2 PF00925.15 KPI34721.1 - 3.1e-52 176.2 0.3 1.7e-41 141.2 0.0 3.6 3 1 1 4 4 4 3 GTP cyclohydrolase II CPSase_L_D2 PF02786.12 KPI34722.1 - 9.8e-17 60.9 0.1 1.1e-16 60.7 0.0 1.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain cobW PF02492.14 KPI34724.1 - 4.7e-35 120.6 0.0 5.7e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KPI34724.1 - 8.7e-06 24.6 0.1 0.02 13.6 0.0 2.1 2 0 0 2 2 2 2 ArgK protein AAA_17 PF13207.1 KPI34724.1 - 0.0057 17.4 0.0 0.01 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Pox_A32 PF04665.7 KPI34724.1 - 0.034 13.4 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein PRK PF00485.13 KPI34724.1 - 0.079 12.5 0.0 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family KAP_NTPase PF07693.9 KPI34724.1 - 0.11 11.5 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.1 KPI34724.1 - 0.13 12.6 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 KPI34724.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA12 PF10443.4 KPI34724.1 - 0.16 10.3 0.0 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein NAD_binding_7 PF13241.1 KPI34725.1 - 2.1e-29 101.8 0.0 3.2e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KPI34725.1 - 1.7e-19 68.8 0.0 2.6e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KPI34725.1 - 1.3e-14 52.8 0.1 2.5e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.1 KPI34725.1 - 0.013 15.6 0.1 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KPI34725.1 - 0.028 14.5 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KPI34725.1 - 0.056 12.3 1.4 6.2 5.6 0.5 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Na_Ca_ex PF01699.19 KPI34726.1 - 6.7e-50 168.3 29.0 2.4e-25 88.7 7.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1352 PF07086.7 KPI34726.1 - 0.32 10.6 2.8 2.2 7.8 1.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1352) TPT PF03151.11 KPI34727.1 - 7.6e-20 71.1 14.2 7.6e-20 71.1 9.9 2.8 3 0 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 KPI34727.1 - 2.1e-14 53.1 20.6 2.9e-14 52.6 14.3 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KPI34727.1 - 2.1e-05 24.5 10.8 2.1e-05 24.5 7.5 3.6 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KPI34727.1 - 0.00018 21.6 4.5 0.00018 21.6 3.1 3.1 2 2 0 2 2 2 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 KPI34727.1 - 0.039 13.0 12.2 0.76 8.8 4.5 2.6 2 1 0 2 2 2 0 Nucleotide-sugar transporter DUF663 PF04950.7 KPI34728.1 - 1.9e-64 217.4 0.0 3.2e-64 216.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KPI34728.1 - 6.8e-22 76.8 0.0 1.4e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Aminotran_3 PF00202.16 KPI34729.1 - 7.4e-75 251.9 0.1 9.4e-54 182.5 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-III PMI_typeI PF01238.16 KPI34730.1 - 5.3e-133 443.6 0.0 6.1e-133 443.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cu_amine_oxid PF01179.15 KPI34731.1 - 1.5e-158 527.9 0.1 1.8e-158 527.6 0.1 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KPI34731.1 - 6.3e-09 35.8 0.0 1.8e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KPI34731.1 - 0.0048 16.9 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain MR_MLE_C PF13378.1 KPI34732.1 - 1.4e-27 95.9 0.1 3.3e-27 94.6 0.1 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KPI34732.1 - 6.9e-20 71.1 0.0 1.6e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 KPI34732.1 - 2.3e-10 40.8 0.0 8.7e-10 38.9 0.0 2.1 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Abhydrolase_4 PF08386.5 KPI34734.1 - 1.9e-21 75.8 0.0 3.5e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KPI34734.1 - 2.6e-12 46.8 0.5 6.8e-12 45.4 0.4 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI34734.1 - 1.1e-10 41.7 0.1 4.2e-10 39.9 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI34734.1 - 0.002 17.9 0.0 0.054 13.2 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family RuBisCO_large PF00016.15 KPI34734.1 - 0.056 12.2 0.0 0.085 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain adh_short PF00106.20 KPI34735.1 - 2.5e-10 40.5 0.0 5.9e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KPI34735.1 - 0.00091 19.2 0.1 0.0024 17.9 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KPI34735.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 KPI34735.1 - 0.0065 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 KPI34735.1 - 0.027 13.8 0.0 0.088 12.2 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_24 PF13578.1 KPI34735.1 - 0.044 14.6 0.0 0.11 13.2 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain K_trans PF02705.11 KPI34736.1 - 8.9e-172 572.1 18.0 1.2e-171 571.7 12.5 1.1 1 0 0 1 1 1 1 K+ potassium transporter DUF3508 PF12018.3 KPI34736.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) AIG2_2 PF13772.1 KPI34738.1 - 1.5e-06 28.2 0.0 2.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 KPI34738.1 - 0.0096 16.3 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family Sugar_tr PF00083.19 KPI34739.1 - 2.7e-59 200.9 20.6 3.3e-59 200.6 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI34739.1 - 8.1e-22 77.4 26.4 8.1e-22 77.4 18.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI34739.1 - 3.4e-06 25.7 14.2 3.1e-05 22.5 1.6 2.7 2 2 1 3 3 3 2 MFS/sugar transport protein DUF3328 PF11807.3 KPI34740.1 - 9e-23 81.0 0.0 1.7e-22 80.2 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) CoA_transf_3 PF02515.12 KPI34741.1 - 1.5e-26 92.8 0.0 2.8e-24 85.4 0.0 2.8 2 1 0 2 2 2 2 CoA-transferase family III Acyl-CoA_dh_1 PF00441.19 KPI34742.1 - 3.9e-36 124.4 1.0 5.7e-36 123.8 0.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KPI34742.1 - 2.4e-20 71.7 0.4 4.6e-20 70.8 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KPI34742.1 - 2e-11 44.4 0.0 1.2e-10 41.9 0.0 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KPI34742.1 - 7e-07 29.5 0.1 1.2e-06 28.8 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1455 PF07306.6 KPI34743.1 - 0.022 14.8 1.1 0.022 14.8 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1455) ABC2_membrane PF01061.19 KPI34744.1 - 3.1e-88 294.4 46.9 1.3e-45 155.1 10.7 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 KPI34744.1 - 1.7e-28 99.6 0.0 1.6e-14 54.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KPI34744.1 - 3.6e-25 87.6 9.5 1.8e-23 82.1 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 KPI34744.1 - 3.8e-11 42.9 0.0 8.4e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 KPI34744.1 - 7.9e-05 21.8 46.9 0.00017 20.7 10.3 3.2 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_17 PF13207.1 KPI34744.1 - 0.0039 17.9 0.0 5.8 7.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KPI34744.1 - 0.011 16.0 0.1 7.6 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KPI34744.1 - 0.017 14.6 0.8 4.3 6.9 0.1 2.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KPI34744.1 - 0.046 13.7 0.5 3.2 7.7 0.1 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 KPI34744.1 - 0.099 12.5 0.2 13 5.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KPI34744.1 - 0.2 10.8 0.4 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KPI34744.1 - 0.2 11.6 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 KPI34744.1 - 0.3 11.3 0.2 26 5.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain p450 PF00067.17 KPI34745.1 - 7.4e-44 150.0 0.0 1.2e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KPI34745.1 - 0.0019 17.1 4.0 0.031 13.1 2.5 3.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_8 PF08022.7 KPI34746.1 - 3.2e-20 71.9 0.1 6e-20 71.0 0.1 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KPI34746.1 - 8.7e-19 67.8 6.7 8.7e-19 67.8 4.6 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KPI34746.1 - 6.8e-06 26.1 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain HAT PF02184.11 KPI34746.1 - 0.22 11.2 3.7 8.4 6.2 0.1 2.6 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat Peptidase_M28 PF04389.12 KPI34747.1 - 2.9e-30 105.3 0.0 4.1e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KPI34747.1 - 4.3e-13 48.8 0.1 8.5e-13 47.8 0.1 1.5 1 0 0 1 1 1 1 PA domain FAD_binding_3 PF01494.14 KPI34748.1 - 8.9e-49 166.4 0.0 1.1e-48 166.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI34748.1 - 6.6e-10 38.4 0.1 1.7e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI34748.1 - 9.8e-06 25.5 0.1 2.3e-05 24.3 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI34748.1 - 0.00011 22.2 0.0 0.0003 20.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KPI34748.1 - 0.00015 20.3 0.1 0.00036 19.1 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KPI34748.1 - 0.00018 20.6 0.1 0.00036 19.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KPI34748.1 - 0.00037 19.6 0.9 0.0011 18.1 0.6 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 KPI34748.1 - 0.0009 18.7 0.0 0.0092 15.4 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 KPI34748.1 - 0.002 17.0 0.7 0.0029 16.5 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KPI34748.1 - 0.0044 17.1 0.1 0.0099 15.9 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI34748.1 - 0.0048 17.2 0.2 0.031 14.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI34748.1 - 0.007 15.3 0.1 0.016 14.1 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 KPI34748.1 - 0.034 14.4 0.0 0.061 13.5 0.0 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 KPI34748.1 - 0.035 13.8 0.1 0.074 12.8 0.1 1.8 1 1 0 1 1 1 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KPI34748.1 - 0.038 13.3 0.0 0.092 12.1 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 KPI34748.1 - 0.039 12.8 0.1 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KPI34748.1 - 0.052 13.1 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 KPI34748.1 - 0.082 11.5 0.2 1.2 7.7 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.13 KPI34748.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Amino_oxidase PF01593.19 KPI34748.1 - 0.14 11.1 0.6 5.4 5.9 0.1 2.7 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase FAA_hydrolase PF01557.13 KPI34749.1 - 2.7e-60 203.5 0.0 3.5e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Sugar_tr PF00083.19 KPI34750.1 - 5.2e-101 338.4 25.7 6e-101 338.2 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI34750.1 - 3.1e-23 82.0 43.4 1.9e-20 72.9 11.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KPI34750.1 - 0.0019 18.2 5.8 0.0086 16.0 0.5 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) 2OG-FeII_Oxy_3 PF13640.1 KPI34751.1 - 0.0023 18.3 0.0 0.005 17.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KPI34751.1 - 0.057 13.7 0.0 0.18 12.1 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FAD_binding_3 PF01494.14 KPI34753.1 - 2.5e-15 56.4 3.6 2.2e-13 49.9 2.5 2.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI34753.1 - 1.5e-09 37.2 3.9 6.6e-06 25.2 1.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI34753.1 - 3.5e-06 26.1 1.9 8.1e-06 24.9 1.0 1.7 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KPI34753.1 - 2.7e-05 24.0 0.2 9.4e-05 22.3 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KPI34753.1 - 0.0005 18.6 0.4 0.002 16.6 0.3 1.8 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KPI34753.1 - 0.0005 20.4 0.1 0.059 13.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI34753.1 - 0.0007 18.7 0.8 0.0028 16.7 0.3 2.1 2 1 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KPI34753.1 - 0.00089 19.1 0.1 0.0023 17.8 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KPI34753.1 - 0.0061 15.6 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SE PF08491.5 KPI34753.1 - 0.011 14.5 0.0 0.034 12.9 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.9 KPI34753.1 - 0.019 13.6 0.3 0.92 8.0 0.1 2.4 3 0 0 3 3 3 0 Tryptophan halogenase FAD_oxidored PF12831.2 KPI34753.1 - 0.055 12.5 0.4 0.087 11.8 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 KPI34753.1 - 0.15 10.9 0.2 0.2 10.4 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.11 KPI34753.1 - 0.18 11.2 0.5 0.68 9.3 0.2 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF3328 PF11807.3 KPI34754.1 - 2.4e-36 125.4 2.7 3.3e-36 125.0 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_transf_28 PF03033.15 KPI34755.1 - 3.9e-20 72.0 0.0 1.5e-19 70.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KPI34755.1 - 6.7e-05 21.6 0.0 0.00011 20.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KPI34755.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain AA_permease PF00324.16 KPI34756.1 - 9.8e-88 294.5 39.8 1.1e-87 294.3 27.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI34756.1 - 2.7e-23 82.1 42.7 3.5e-23 81.8 29.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 KPI34756.1 - 0.045 13.4 0.6 0.045 13.4 0.4 3.8 5 0 0 5 5 5 0 Domain of unknown function (DUF1772) ADH_zinc_N PF00107.21 KPI34757.1 - 5.3e-09 35.7 0.0 2.7e-08 33.4 0.0 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI34757.1 - 0.018 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain TRI12 PF06609.8 KPI34758.1 - 3.1e-23 81.8 12.9 4.1e-23 81.4 9.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI34758.1 - 0.00014 20.7 44.9 0.0022 16.7 25.3 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KPI34759.1 - 1.8e-08 33.3 1.7 1.5e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF3500 PF12006.3 KPI34760.1 - 2e-86 289.7 0.0 2.4e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) FAD_binding_3 PF01494.14 KPI34761.1 - 2e-51 175.1 0.0 2.3e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI34761.1 - 2.5e-06 26.6 0.2 0.024 13.5 0.0 2.4 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KPI34761.1 - 1e-05 25.7 0.0 1.7e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI34761.1 - 7.1e-05 23.1 0.1 0.0014 18.9 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI34761.1 - 0.00011 22.1 0.0 0.00052 19.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI34761.1 - 0.00086 18.2 1.2 0.083 11.7 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KPI34761.1 - 0.0033 17.4 0.0 0.01 15.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KPI34761.1 - 0.0045 16.1 0.3 0.02 13.9 0.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 KPI34761.1 - 0.019 14.3 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 KPI34761.1 - 0.024 13.1 0.0 0.04 12.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 KPI34761.1 - 0.026 13.6 0.0 0.11 11.6 0.0 2.0 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 KPI34761.1 - 0.041 12.9 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family PALP PF00291.20 KPI34762.1 - 2e-30 106.0 0.0 2.4e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pkinase PF00069.20 KPI34763.1 - 1.9e-50 171.4 0.0 2.7e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI34763.1 - 1.4e-25 89.8 0.0 1.8e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KPI34763.1 - 6.8e-06 25.9 0.0 1.6e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KPI34763.1 - 0.0092 14.9 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KPI34763.1 - 0.02 14.2 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 KPI34763.1 - 0.058 12.9 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 KPI34763.1 - 0.064 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1929 PF09118.6 KPI34764.1 - 1.5e-20 73.1 0.1 3.8e-20 71.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) PAN_1 PF00024.21 KPI34764.1 - 1.6e-10 40.6 8.5 8e-05 22.3 0.6 2.5 2 0 0 2 2 2 2 PAN domain Kelch_6 PF13964.1 KPI34764.1 - 9.7e-09 35.0 7.4 0.0044 17.1 0.2 4.7 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.20 KPI34764.1 - 4.9e-08 32.3 5.1 5.9e-06 25.7 0.3 4.0 4 0 0 4 4 4 1 Kelch motif PAN_4 PF14295.1 KPI34764.1 - 1.6e-07 30.8 5.2 0.0017 18.0 0.7 2.6 2 0 0 2 2 2 2 PAN domain PAN_3 PF08277.7 KPI34764.1 - 2.4e-05 23.8 2.0 0.033 13.7 0.1 2.6 2 0 0 2 2 2 2 PAN-like domain PAN_2 PF08276.6 KPI34764.1 - 7.7e-05 22.4 10.1 0.00041 20.1 1.3 2.6 2 0 0 2 2 2 2 PAN-like domain Glyoxal_oxid_N PF07250.6 KPI34764.1 - 9.3e-05 21.6 0.2 0.031 13.3 0.0 2.5 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_4 PF13418.1 KPI34764.1 - 0.0015 18.2 8.3 2.4 8.0 0.7 4.8 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.1 KPI34764.1 - 0.002 18.2 1.6 4.7 7.5 0.0 4.0 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 KPI34764.1 - 0.014 15.1 2.8 0.15 11.8 0.2 3.6 4 0 0 4 4 4 0 Kelch motif MANEC PF07502.9 KPI34764.1 - 0.18 11.8 3.9 0.3 11.1 0.3 2.4 2 0 0 2 2 2 0 MANEC domain Peptidase_S28 PF05577.7 KPI34765.1 - 2.4e-38 131.8 3.8 1.5e-36 125.9 2.6 2.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 FMN_bind_2 PF04299.7 KPI34766.1 - 0.042 13.3 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative FMN-binding domain Pkinase PF00069.20 KPI34767.1 - 2.8e-38 131.5 0.0 3.6e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI34767.1 - 1.1e-20 73.8 0.0 1.6e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KPI34767.1 - 0.0078 15.9 0.3 0.024 14.3 0.2 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KPI34767.1 - 0.063 12.0 0.1 0.11 11.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KPI34767.1 - 0.13 11.5 0.1 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF3328 PF11807.3 KPI34768.1 - 1.3e-33 116.5 0.5 1.6e-33 116.2 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) p450 PF00067.17 KPI34769.1 - 8.9e-65 218.9 0.0 1.2e-64 218.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 KPI34771.1 - 3.1e-27 95.4 1.5 7.2e-27 94.2 0.4 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_10 PF13374.1 KPI34773.1 - 0.31 11.0 2.1 2.5 8.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PAS_9 PF13426.1 KPI34776.1 - 4.5e-28 97.6 0.0 6.1e-18 65.1 0.0 3.7 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 KPI34776.1 - 3.9e-17 62.1 0.0 2.6e-10 40.2 0.0 3.7 3 0 0 3 3 3 3 PAS fold GATA PF00320.22 KPI34776.1 - 1.6e-14 52.9 7.6 3.5e-14 51.8 5.3 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 KPI34776.1 - 1.1e-13 50.9 0.0 0.00025 20.8 0.0 4.0 3 1 0 3 3 3 3 PAS fold PAS_11 PF14598.1 KPI34776.1 - 4.6e-13 49.1 0.0 3.3e-07 30.2 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KPI34776.1 - 3.1e-10 40.0 0.0 0.00091 19.2 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.6 KPI34776.1 - 0.00074 19.9 0.0 0.0075 16.7 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 KPI34776.1 - 0.078 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 PAS domain PAS_10 PF13596.1 KPI34776.1 - 0.11 12.8 0.0 6.2 7.1 0.0 2.5 2 0 0 2 2 2 0 PAS domain Coatomer_WDAD PF04053.9 KPI34777.1 - 9.5e-144 479.4 0.0 1.6e-143 478.7 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 KPI34777.1 - 4.9e-92 308.6 0.0 7.5e-92 308.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KPI34777.1 - 1.2e-49 164.4 9.1 9.6e-09 34.8 0.1 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KPI34777.1 - 0.00016 19.9 6.6 0.87 7.6 0.0 3.6 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Peptidase_C12 PF01088.16 KPI34778.1 - 1.2e-32 112.8 0.0 1.2e-19 70.3 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 KxDL PF10241.4 KPI34780.1 - 5.8e-24 83.8 0.9 7.8e-24 83.3 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein Sec23_trunk PF04811.10 KPI34781.1 - 1.4e-76 257.0 0.0 2e-76 256.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KPI34781.1 - 2.1e-33 113.8 0.1 4e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KPI34781.1 - 1.3e-29 102.5 0.0 3.9e-29 101.0 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KPI34781.1 - 4.5e-16 58.1 2.9 8.3e-16 57.2 2.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KPI34781.1 - 3.4e-10 39.4 0.0 8.5e-10 38.1 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat ABC2_membrane PF01061.19 KPI34782.1 - 3.2e-79 264.9 55.9 7.1e-45 152.7 16.3 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 KPI34782.1 - 6.2e-38 130.2 0.6 4.4e-18 65.9 0.0 3.6 4 0 0 4 4 3 2 ABC transporter PDR_CDR PF06422.7 KPI34782.1 - 6.1e-36 122.1 0.2 4.2e-33 113.0 0.0 3.4 2 0 0 2 2 2 1 CDR ABC transporter ABC_trans_N PF14510.1 KPI34782.1 - 6.2e-19 67.8 2.3 3.3e-18 65.5 0.0 3.0 4 0 0 4 4 2 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 KPI34782.1 - 1.1e-08 34.5 10.0 1.1e-08 34.5 6.9 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KPI34782.1 - 1.3e-08 34.5 0.1 6.2e-06 25.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KPI34782.1 - 5.5e-06 25.6 0.1 0.00032 19.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KPI34782.1 - 2e-05 24.4 0.0 0.018 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KPI34782.1 - 2.2e-05 24.5 0.9 0.00052 20.0 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KPI34782.1 - 2.5e-05 23.6 0.8 0.0044 16.5 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 KPI34782.1 - 5.8e-05 23.1 0.0 0.29 11.0 0.0 3.1 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.14 KPI34782.1 - 0.00017 20.8 0.0 0.23 10.6 0.0 4.0 4 1 0 4 4 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.14 KPI34782.1 - 0.00024 20.6 0.2 0.017 14.6 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KPI34782.1 - 0.00099 19.2 0.0 0.32 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KPI34782.1 - 0.0043 16.5 0.3 0.4 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 KPI34782.1 - 0.0052 17.0 0.0 0.12 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KPI34782.1 - 0.012 15.3 0.1 6.8 6.5 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 KPI34782.1 - 0.013 15.1 1.3 0.63 9.6 0.1 2.7 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 KPI34782.1 - 0.014 16.2 0.0 0.46 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KPI34782.1 - 0.024 14.2 0.4 0.9 9.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KPI34782.1 - 0.03 14.6 0.3 0.21 11.8 0.0 2.5 3 0 0 3 3 1 0 AAA domain AAA PF00004.24 KPI34782.1 - 0.039 14.1 0.0 14 5.8 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 KPI34782.1 - 0.058 13.8 0.0 14 6.1 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 KPI34782.1 - 0.087 12.9 0.2 5.1 7.3 0.0 3.0 3 0 0 3 3 2 0 RNA helicase T2SE PF00437.15 KPI34782.1 - 0.13 11.1 0.1 4 6.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.1 KPI34782.1 - 0.56 9.2 0.0 2.3 7.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Phtf-FEM1B_bdg PF12129.3 KPI34782.1 - 3.5 6.9 5.8 1.2 8.4 1.6 2.0 2 0 0 2 2 1 0 Male germ-cell putative homeodomain transcription factor AAA_24 PF13479.1 KPI34782.1 - 4.5 6.8 6.5 26 4.3 0.2 3.2 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.11 KPI34785.1 - 6.3e-21 74.4 24.1 3.5e-17 62.1 10.4 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily PgaD PF13994.1 KPI34785.1 - 0.027 13.9 3.0 0.2 11.1 0.0 2.9 3 1 0 3 3 3 0 PgaD-like protein NfeD PF01957.13 KPI34785.1 - 0.45 10.6 12.7 4.6 7.3 0.1 3.8 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding eIF2A PF08662.6 KPI34786.1 - 4.5e-83 277.7 0.0 3.8e-81 271.4 0.0 2.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KPI34786.1 - 0.001 18.8 2.0 6.5 6.8 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat FlaG PF03646.10 KPI34786.1 - 2.1 8.5 5.3 2.7 8.1 0.0 3.1 3 0 0 3 3 3 0 FlaG protein HUN PF08729.5 KPI34787.1 - 2.5e-13 49.6 0.1 5e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain EMP70 PF02990.11 KPI34788.1 - 2.7e-188 626.6 0.3 3.5e-188 626.3 0.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 NfeD PF01957.13 KPI34788.1 - 0.089 12.9 0.0 0.089 12.9 0.0 4.4 3 2 2 5 5 5 0 NfeD-like C-terminal, partner-binding Rapsyn_N PF10579.4 KPI34788.1 - 0.17 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region Rb_C PF08934.5 KPI34789.1 - 0.51 9.9 6.0 0.053 13.1 0.6 2.0 2 0 0 2 2 2 0 Rb C-terminal domain Abhydrolase_6 PF12697.2 KPI34790.1 - 1.2e-11 44.8 0.0 1.9e-11 44.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI34790.1 - 0.0006 19.5 0.0 0.00087 19.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI34790.1 - 0.011 15.3 0.0 0.85 9.1 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.8 KPI34790.1 - 0.018 14.6 0.5 0.076 12.5 0.0 2.1 3 0 0 3 3 3 0 PGAP1-like protein AAA PF00004.24 KPI34791.1 - 5.2e-49 165.8 0.0 2.9e-38 131.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KPI34791.1 - 8.2e-11 41.7 0.0 1.9e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 KPI34791.1 - 2.7e-09 36.5 0.1 2.5e-07 30.2 0.0 3.2 3 0 0 3 3 3 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 KPI34791.1 - 4.9e-07 29.9 0.1 0.00073 19.6 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KPI34791.1 - 2.7e-06 28.1 0.1 0.016 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KPI34791.1 - 5e-06 26.8 0.1 0.024 14.9 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KPI34791.1 - 5.5e-06 26.4 0.1 0.01 15.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.9 KPI34791.1 - 2.9e-05 24.0 0.0 7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 KPI34791.1 - 4.4e-05 23.1 0.9 0.025 14.3 0.0 2.9 3 0 0 3 3 2 1 Part of AAA domain AAA_25 PF13481.1 KPI34791.1 - 4.7e-05 22.8 0.9 0.59 9.5 0.0 3.4 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.1 KPI34791.1 - 5.3e-05 23.1 0.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KPI34791.1 - 8.1e-05 22.6 0.0 0.53 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KPI34791.1 - 9.9e-05 22.2 0.1 0.13 12.1 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 KPI34791.1 - 9.9e-05 22.0 0.1 0.0023 17.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KPI34791.1 - 0.0001 21.1 0.1 0.035 12.8 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus Mg_chelatase PF01078.16 KPI34791.1 - 0.00012 21.3 0.5 0.0044 16.2 0.0 2.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 KPI34791.1 - 0.00034 19.7 0.1 0.14 11.2 0.1 3.0 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KPI34791.1 - 0.00046 20.3 0.0 0.19 11.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.1 KPI34791.1 - 0.0023 17.5 0.6 0.36 10.3 0.1 3.1 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 KPI34791.1 - 0.0029 17.0 0.4 0.047 13.1 0.0 2.6 3 0 0 3 3 3 1 IstB-like ATP binding protein ABC_tran PF00005.22 KPI34791.1 - 0.0035 17.6 0.1 0.028 14.7 0.1 2.4 2 0 0 2 2 2 1 ABC transporter KaiC PF06745.8 KPI34791.1 - 0.0048 16.0 0.6 0.043 12.9 0.1 2.4 2 1 0 2 2 2 1 KaiC KTI12 PF08433.5 KPI34791.1 - 0.011 14.9 0.0 0.65 9.1 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NACHT PF05729.7 KPI34791.1 - 0.02 14.5 2.0 9.6 5.8 0.0 3.6 4 0 0 4 4 3 0 NACHT domain Zeta_toxin PF06414.7 KPI34791.1 - 0.04 13.0 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ATP-synt_ab PF00006.20 KPI34791.1 - 0.049 13.1 0.1 3.7 6.9 0.0 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 KPI34791.1 - 0.059 12.2 0.4 3 6.5 0.1 2.6 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.11 KPI34791.1 - 0.069 12.3 0.1 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.12 KPI34791.1 - 0.1 11.4 0.0 3.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 KPI34791.1 - 0.14 11.8 0.1 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 HET PF06985.6 KPI34792.1 - 4.2e-24 85.2 1.1 3e-19 69.5 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PCI PF01399.22 KPI34793.1 - 3.4e-20 72.3 0.8 9.5e-20 70.8 0.1 2.1 2 0 0 2 2 2 1 PCI domain TPR_12 PF13424.1 KPI34793.1 - 0.00058 19.7 10.3 0.58 10.1 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KPI34793.1 - 0.003 17.2 3.0 9 6.3 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat DDRGK PF09756.4 KPI34793.1 - 0.0035 16.7 0.1 0.0076 15.6 0.1 1.6 1 0 0 1 1 1 1 DDRGK domain Peptidase_M16_C PF05193.16 KPI34793.1 - 0.023 14.3 0.1 0.053 13.1 0.0 1.8 2 0 0 2 2 2 0 Peptidase M16 inactive domain TPR_1 PF00515.23 KPI34793.1 - 0.089 12.4 4.0 33 4.3 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KPI34793.1 - 0.16 12.6 9.2 4 8.2 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat Paramecium_SA PF01508.11 KPI34795.1 - 1.1 9.5 5.0 3.9 7.7 3.4 2.0 1 1 0 1 1 1 0 Paramecium surface antigen domain Voltage_CLC PF00654.15 KPI34797.1 - 2.3e-79 267.0 14.9 1.5e-77 261.0 10.3 2.4 1 1 0 1 1 1 1 Voltage gated chloride channel RPAP1_C PF08620.5 KPI34798.1 - 1.1e-28 98.8 0.0 2.1e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 KPI34798.1 - 1.1e-14 53.6 3.6 2.2e-14 52.7 2.5 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal DUF3921 PF13060.1 KPI34798.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) Amidohydro_2 PF04909.9 KPI34799.1 - 2.3e-46 158.5 0.1 2.7e-46 158.3 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase Acetyltransf_13 PF13880.1 KPI34800.1 - 1e-26 92.4 0.0 2.2e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 KPI34800.1 - 3.9e-10 39.1 0.2 7.8e-10 38.1 0.2 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 KPI34800.1 - 0.067 13.2 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family WD40 PF00400.27 KPI34801.1 - 3.8e-38 128.0 7.5 1.2e-08 34.4 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.9 KPI34801.1 - 7.2e-32 109.2 11.3 1.2e-31 108.5 7.8 1.3 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 KPI34801.1 - 0.00037 20.2 0.3 0.0023 17.6 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KPI34801.1 - 0.015 13.6 0.1 0.053 11.8 0.0 1.8 1 1 0 1 1 1 0 Cytochrome D1 heme domain MmgE_PrpD PF03972.9 KPI34802.1 - 4.6e-52 176.6 0.0 5.5e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF3405 PF11885.3 KPI34803.1 - 6.9e-161 535.8 6.5 8.7e-161 535.5 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) HATPase_c PF02518.21 KPI34804.1 - 6.7e-25 86.9 0.2 2e-24 85.4 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KPI34804.1 - 6.8e-17 61.2 0.0 2.1e-16 59.6 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 KPI34804.1 - 4.2e-16 58.9 0.0 1.3e-09 38.0 0.0 3.1 2 1 1 3 3 3 2 Response regulator receiver domain PAS_3 PF08447.6 KPI34804.1 - 8.8e-09 35.3 0.6 0.011 15.7 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 KPI34804.1 - 1.6e-07 31.6 0.0 0.0025 18.1 0.0 3.7 3 1 0 3 3 3 2 PAS domain PAS_4 PF08448.5 KPI34804.1 - 0.00054 19.9 0.0 0.05 13.6 0.0 3.2 3 0 0 3 3 3 1 PAS fold Peptidase_M13_N PF05649.8 KPI34805.1 - 5.2e-53 180.5 0.0 9.4e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 DUF883 PF05957.8 KPI34805.1 - 3.2 8.2 10.8 0.15 12.4 2.9 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HET PF06985.6 KPI34806.1 - 2.3e-06 27.8 0.1 3.9e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EF-hand_1 PF00036.27 KPI34807.1 - 1.1e-24 83.8 5.3 3.2e-08 32.3 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 KPI34807.1 - 8.7e-22 77.0 0.8 5.2e-13 48.9 0.1 2.9 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KPI34807.1 - 1.3e-21 74.4 1.8 4.1e-06 26.2 0.1 5.0 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 KPI34807.1 - 4.7e-17 60.4 4.1 7.2e-06 25.1 0.0 4.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KPI34807.1 - 1.1e-14 53.7 7.3 3e-06 26.7 0.4 4.1 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KPI34807.1 - 2.7e-08 33.4 4.2 0.0081 15.8 0.0 3.7 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KPI34807.1 - 0.00012 22.1 0.8 0.17 11.9 0.1 3.2 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 KPI34807.1 - 0.00059 19.6 0.2 0.011 15.6 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_2 PF09068.6 KPI34807.1 - 0.01 15.9 0.1 1.5 8.9 0.0 2.9 3 0 0 3 3 3 0 EF hand EF-hand_10 PF14788.1 KPI34807.1 - 0.054 13.1 0.3 7.8 6.2 0.0 3.4 3 0 0 3 3 3 0 EF hand S10_plectin PF03501.10 KPI34807.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Plectin/S10 domain Mad3_BUB1_II PF08171.6 KPI34807.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 Jag_N PF14804.1 KPI34808.1 - 0.096 12.7 0.4 8.2 6.5 0.1 2.9 2 0 0 2 2 2 0 Jag N-terminus FAM176 PF14851.1 KPI34809.1 - 0.16 11.6 0.5 0.24 11.0 0.4 1.4 1 0 0 1 1 1 0 FAM176 family BSP_II PF05432.6 KPI34809.1 - 0.23 10.6 5.0 0.34 10.1 3.4 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RXT2_N PF08595.6 KPI34809.1 - 0.73 9.6 4.0 0.29 10.9 1.1 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal Myc_N PF01056.13 KPI34809.1 - 0.8 8.8 8.3 1.2 8.2 5.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.7 KPI34809.1 - 1.1 8.4 6.4 1.7 7.8 4.5 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.1 KPI34809.1 - 1.3 9.2 14.4 5.1 7.3 4.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.5 KPI34809.1 - 2.1 8.6 17.2 0.43 10.8 9.2 1.9 2 1 0 2 2 2 0 Centromere protein B dimerisation domain Spo7 PF03907.8 KPI34810.1 - 6.5e-58 195.7 0.6 9e-58 195.3 0.4 1.2 1 0 0 1 1 1 1 Spo7-like protein Macoilin PF09726.4 KPI34810.1 - 0.84 7.8 12.1 1.1 7.5 8.4 1.1 1 0 0 1 1 1 0 Transmembrane protein NTP_transferase PF00483.18 KPI34811.1 - 1e-45 155.9 0.0 2.5e-45 154.7 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 KPI34811.1 - 1.9e-12 46.1 9.0 1e-09 37.4 1.5 3.8 1 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KPI34811.1 - 1.1e-10 41.7 0.0 2.4e-10 40.7 0.0 1.6 2 0 0 2 2 2 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KPI34811.1 - 2e-05 24.0 2.7 2e-05 24.0 1.9 3.0 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 KPI34811.1 - 0.0097 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase RabGAP-TBC PF00566.13 KPI34812.1 - 7e-32 110.6 0.0 8.9e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GMC_oxred_N PF00732.14 KPI34814.1 - 2.3e-52 178.0 0.0 3e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI34814.1 - 7.3e-28 97.6 0.0 1.5e-27 96.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KPI34814.1 - 1.5e-09 37.1 0.0 5.7e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KPI34814.1 - 5.2e-07 29.5 0.0 1.3e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI34814.1 - 3e-06 27.2 0.1 0.019 14.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI34814.1 - 0.00018 20.5 0.1 0.00076 18.4 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KPI34814.1 - 0.0079 14.7 0.0 0.058 11.8 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KPI34814.1 - 0.011 14.7 0.1 0.027 13.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KPI34814.1 - 0.016 15.2 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI34814.1 - 0.03 14.7 0.5 0.19 12.1 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI34814.1 - 0.052 12.4 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KPI34814.1 - 0.14 11.2 0.1 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain WD40 PF00400.27 KPI34815.1 - 0.00068 19.4 0.2 1.2 9.1 0.1 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF2415 PF10313.4 KPI34815.1 - 0.0038 16.8 0.1 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Rad9_Rad53_bind PF08605.5 KPI34815.1 - 0.046 13.4 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding Proteasome_A_N PF10584.4 KPI34815.1 - 0.21 10.9 1.2 1.3 8.3 0.0 2.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Lactamase_B PF00753.22 KPI34816.1 - 0.0002 21.0 0.0 0.00038 20.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily SAM_2 PF07647.12 KPI34817.1 - 7.7e-07 28.8 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KPI34817.1 - 5.6e-05 23.2 0.1 0.00012 22.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) T2SM PF04612.7 KPI34818.1 - 0.5 10.1 5.2 0.83 9.4 3.6 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M TFIIF_alpha PF05793.7 KPI34819.1 - 6.7e-09 34.6 39.7 6.7e-09 34.6 27.5 2.0 1 1 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TPP_enzyme_N PF02776.13 KPI34820.1 - 3.3e-36 124.3 0.0 4.9e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KPI34820.1 - 4.9e-15 55.5 0.0 1.3e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KPI34820.1 - 2.9e-14 52.8 0.3 2.1e-13 50.0 0.0 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Baculo_gp64 PF03273.8 KPI34820.1 - 0.11 10.6 0.0 0.16 10.0 0.0 1.2 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family adh_short PF00106.20 KPI34821.1 - 2.4e-16 60.1 0.1 3.5e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI34821.1 - 1.6e-10 41.2 0.1 2.2e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI34821.1 - 5.2e-06 26.2 0.1 1.4e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI34821.1 - 0.0014 18.0 0.0 0.57 9.5 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KPI34821.1 - 0.0037 17.3 0.0 0.0063 16.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 KPI34821.1 - 0.022 13.8 0.0 0.056 12.5 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KPI34821.1 - 0.036 13.8 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PetM PF08041.6 KPI34822.1 - 0.12 11.8 7.9 2.4 7.7 0.6 2.5 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 Ribosomal_S8e PF01201.17 KPI34824.1 - 1.7e-36 125.2 3.6 2.2e-35 121.7 2.5 2.1 1 1 0 1 1 1 1 Ribosomal protein S8e DUF2390 PF09523.5 KPI34824.1 - 0.16 12.1 6.4 0.33 11.1 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) FHIPEP PF00771.15 KPI34824.1 - 0.49 8.6 2.0 0.63 8.3 1.4 1.1 1 0 0 1 1 1 0 FHIPEP family MatE PF01554.13 KPI34825.1 - 2.7e-47 160.3 20.9 3.4e-29 101.5 3.6 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KPI34825.1 - 7.6e-10 38.7 5.9 7.6e-10 38.7 4.1 3.5 2 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain TisB_toxin PF13939.1 KPI34825.1 - 0.064 12.9 1.7 0.15 11.8 1.2 1.5 1 0 0 1 1 1 0 Toxin TisB, type I toxin-antitoxin system Cyclin_N PF00134.18 KPI34826.1 - 3.6e-07 29.7 0.0 8e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KPI34826.1 - 4.7e-07 30.3 0.0 1.3e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Cyclin Abhydrolase_6 PF12697.2 KPI34828.1 - 5.4e-32 111.5 0.0 2.2e-29 102.9 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI34828.1 - 3e-18 66.2 0.0 3.7e-17 62.6 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI34828.1 - 4.9e-14 52.3 0.0 5.2e-11 42.5 0.0 2.6 2 1 1 3 3 3 2 Alpha/beta hydrolase family Esterase PF00756.15 KPI34828.1 - 3e-07 30.1 0.0 5.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 KPI34828.1 - 8.4e-06 25.0 0.0 1.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2305 PF10230.4 KPI34828.1 - 0.00033 20.1 0.0 0.00052 19.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_2 PF02230.11 KPI34828.1 - 0.00038 19.9 0.0 1 8.7 0.0 2.8 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 KPI34828.1 - 0.00041 19.3 0.0 0.00082 18.3 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 KPI34828.1 - 0.00049 19.9 0.5 0.0014 18.4 0.0 2.0 3 0 0 3 3 1 1 Putative lysophospholipase Thioesterase PF00975.15 KPI34828.1 - 0.004 17.4 0.3 0.057 13.6 0.2 2.3 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 KPI34828.1 - 0.006 16.1 0.0 0.041 13.4 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KPI34828.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S15 PF02129.13 KPI34828.1 - 0.023 14.1 0.3 1.8 7.9 0.1 3.2 4 0 0 4 4 4 0 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.20 KPI34828.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.6 KPI34828.1 - 0.033 12.9 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Ser_hydrolase PF06821.8 KPI34828.1 - 0.053 13.1 0.1 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase DUF2048 PF09752.4 KPI34828.1 - 0.058 12.2 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) ATG16 PF08614.6 KPI34829.1 - 4.3e-05 23.4 11.0 4.3e-05 23.4 7.6 4.8 1 1 3 4 4 4 1 Autophagy protein 16 (ATG16) Spc42p PF11544.3 KPI34829.1 - 0.00014 21.7 0.2 0.00014 21.7 0.2 4.4 3 1 2 5 5 4 1 Spindle pole body component Spc42p DUF4200 PF13863.1 KPI34829.1 - 0.00053 19.9 40.8 0.0067 16.3 5.6 4.9 1 1 2 4 4 4 3 Domain of unknown function (DUF4200) IncA PF04156.9 KPI34829.1 - 0.00063 19.4 48.5 0.001 18.6 10.2 4.2 1 1 1 3 3 3 2 IncA protein Tropomyosin_1 PF12718.2 KPI34829.1 - 0.00077 19.3 17.9 0.00077 19.3 12.4 3.8 1 1 1 3 3 3 1 Tropomyosin like Spc7 PF08317.6 KPI34829.1 - 0.00087 18.0 9.2 0.00087 18.0 6.4 3.0 1 1 2 3 3 3 2 Spc7 kinetochore protein Reo_sigmaC PF04582.7 KPI34829.1 - 0.01 15.0 14.2 0.12 11.5 3.5 2.7 1 1 2 3 3 3 3 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 KPI34829.1 - 0.019 14.7 10.6 0.019 14.7 7.3 6.7 2 2 4 7 7 7 0 TATA element modulatory factor 1 DNA binding RL11D PF11088.3 KPI34829.1 - 0.045 13.5 0.2 0.097 12.4 0.2 1.5 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 Bacillus_HBL PF05791.6 KPI34829.1 - 0.55 9.5 21.0 0.38 10.0 3.3 3.6 1 1 3 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) Filament PF00038.16 KPI34829.1 - 0.56 9.6 45.4 9.3 5.6 15.6 3.2 1 1 1 2 2 2 0 Intermediate filament protein DUF972 PF06156.8 KPI34829.1 - 0.58 10.5 31.4 0.59 10.4 4.0 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF972) Mod_r PF07200.8 KPI34829.1 - 0.68 9.8 35.6 0.28 11.1 3.2 3.4 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein TMF_TATA_bd PF12325.3 KPI34829.1 - 2.6 7.8 36.7 0.39 10.4 4.0 5.2 1 1 4 5 5 5 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 KPI34829.1 - 4.1 7.2 48.4 0.043 13.7 1.3 5.0 1 1 4 5 5 4 0 Afadin- and alpha -actinin-Binding zf-ZPR1 PF03367.8 KPI34829.1 - 7.3 5.7 12.1 0.093 11.8 1.0 3.1 1 1 3 4 4 4 0 ZPR1 zinc-finger domain DUF904 PF06005.7 KPI34829.1 - 9.4 6.6 40.5 1.8 8.8 1.8 5.9 3 2 1 5 5 5 0 Protein of unknown function (DUF904) FliJ PF02050.11 KPI34829.1 - 9.9 6.2 40.2 1.2 9.1 5.3 5.4 1 1 5 6 6 6 0 Flagellar FliJ protein SRP40_C PF05022.7 KPI34830.1 - 1.8e-21 76.3 3.4 3.1e-21 75.6 2.3 1.4 1 0 0 1 1 1 1 SRP40, C-terminal domain GET2 PF08690.5 KPI34830.1 - 1.4 8.0 3.4 1.8 7.7 2.4 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4207 PF13904.1 KPI34831.1 - 0.01 15.2 3.2 0.011 15.1 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) WW PF00397.21 KPI34832.1 - 3.2e-06 26.8 8.0 7.3e-06 25.7 5.5 1.7 1 0 0 1 1 1 1 WW domain DUF1090 PF06476.7 KPI34832.1 - 0.0013 18.4 0.1 0.0023 17.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1090) DUF4398 PF14346.1 KPI34832.1 - 0.13 12.3 2.0 0.26 11.3 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) SMN PF06003.7 KPI34832.1 - 0.18 10.9 18.5 0.041 12.9 5.2 2.4 2 1 0 2 2 2 0 Survival motor neuron protein (SMN) DUF4175 PF13779.1 KPI34832.1 - 0.9 7.1 13.3 0.056 11.1 1.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4175) TPR_11 PF13414.1 KPI34833.1 - 3.9e-13 48.8 14.1 0.0031 17.1 0.0 6.8 6 2 2 8 8 8 6 TPR repeat TPR_2 PF07719.12 KPI34833.1 - 8.8e-10 37.7 18.6 0.38 10.7 0.0 9.3 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 KPI34833.1 - 9.6e-09 35.6 20.1 0.082 13.6 0.0 6.5 6 1 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 KPI34833.1 - 2.2e-08 34.0 6.4 0.0008 19.5 0.4 3.6 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KPI34833.1 - 8e-08 32.5 13.7 0.00054 20.2 0.5 5.8 6 1 0 6 6 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KPI34833.1 - 8.4e-08 32.1 18.8 0.014 15.9 0.0 7.8 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 KPI34833.1 - 4.1e-06 26.5 0.3 0.096 12.9 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KPI34833.1 - 1.3e-05 24.9 14.3 0.65 9.9 0.0 6.3 4 2 2 7 7 7 4 Tetratricopeptide repeat NARP1 PF12569.3 KPI34833.1 - 0.00066 18.5 0.0 0.011 14.5 0.0 2.2 1 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_1 PF00515.23 KPI34833.1 - 0.0014 18.1 11.3 4.8 6.9 0.0 7.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.1 KPI34833.1 - 0.0029 17.2 1.5 9 6.3 0.0 5.7 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 KPI34833.1 - 0.018 15.1 1.4 0.4 10.8 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KPI34833.1 - 0.024 15.0 3.5 4.4 7.9 0.0 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat Sec3_C PF09763.4 KPI34834.1 - 5.1e-176 586.8 11.2 7e-176 586.3 7.8 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 KPI34834.1 - 1.2e-29 102.0 0.1 2.5e-29 100.9 0.1 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 KPI34834.1 - 0.0089 14.6 2.1 0.018 13.6 0.4 2.0 2 0 0 2 2 2 1 Vps52 / Sac2 family Sec3_C_2 PF15278.1 KPI34834.1 - 0.086 12.9 0.1 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Sec3 exocyst complex subunit DUF4050 PF13259.1 KPI34835.1 - 3.6e-29 101.1 0.0 3.6e-29 101.1 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF4050) Macoilin PF09726.4 KPI34835.1 - 4.5 5.4 15.1 6.9 4.8 10.5 1.3 1 0 0 1 1 1 0 Transmembrane protein His_Phos_2 PF00328.17 KPI34836.1 - 3.7e-30 105.4 0.0 6.1e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MCLC PF05934.6 KPI34838.1 - 6.4 4.9 7.5 16 3.6 5.2 1.6 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) GWT1 PF06423.7 KPI34839.1 - 0.17 11.9 3.4 0.16 12.0 1.2 1.9 1 1 1 2 2 2 0 GWT1 RIB43A PF05914.7 KPI34840.1 - 0.045 12.3 0.6 0.061 11.9 0.4 1.2 1 0 0 1 1 1 0 RIB43A Herpes_BLLF1 PF05109.8 KPI34840.1 - 2.1 6.1 12.3 2.3 6.0 8.5 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Rab5ip PF07019.7 KPI34841.1 - 1.9e-12 47.0 6.5 1.7e-11 44.0 4.5 2.2 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Suc_Fer-like PF06999.7 KPI34842.1 - 4e-34 118.6 0.0 1.9e-33 116.4 0.0 1.9 1 1 0 1 1 1 1 Sucrase/ferredoxin-like DUF4609 PF15382.1 KPI34842.1 - 0.02 14.5 0.4 0.063 13.0 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4609) HALZ PF02183.13 KPI34843.1 - 0.034 13.8 0.4 0.065 12.9 0.3 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper HMGL-like PF00682.14 KPI34845.1 - 7.5e-70 235.2 0.6 1.2e-69 234.5 0.4 1.3 1 0 0 1 1 1 1 HMGL-like HSP70 PF00012.15 KPI34846.1 - 8.8e-267 885.9 16.6 1e-266 885.7 11.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KPI34846.1 - 4.1e-15 55.2 6.8 2.8e-13 49.1 1.9 2.6 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KPI34846.1 - 0.00036 20.2 0.0 0.0011 18.6 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KPI34846.1 - 0.021 14.6 11.7 10 5.9 3.5 4.6 2 2 0 2 2 2 0 Cell division protein FtsA DnaG_DnaB_bind PF08278.6 KPI34846.1 - 0.24 11.6 2.8 0.6 10.3 1.0 2.4 3 0 0 3 3 3 0 DNA primase DnaG DnaB-binding Med9 PF07544.8 KPI34846.1 - 0.72 9.6 4.8 1.6 8.5 0.5 2.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DSHCT PF08148.7 KPI34847.1 - 3e-59 199.2 1.7 6.6e-59 198.1 0.3 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 KPI34847.1 - 2.8e-21 75.7 0.1 7.4e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI34847.1 - 3.4e-06 26.8 0.0 1.2e-05 25.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI34847.1 - 0.0029 17.4 0.3 0.065 13.0 0.1 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit rRNA_proc-arch PF13234.1 KPI34847.1 - 0.12 11.5 2.0 0.28 10.2 1.4 1.7 1 1 0 1 1 1 0 rRNA-processing arch domain WD40 PF00400.27 KPI34848.1 - 2.8e-17 61.8 4.0 1.2e-08 34.4 0.3 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat CHCH PF06747.8 KPI34849.1 - 9.1e-07 28.6 3.2 1.6e-06 27.8 2.2 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 KPI34849.1 - 0.27 11.3 1.7 0.58 10.3 1.2 1.5 1 0 0 1 1 1 0 GCK domain Sec10 PF07393.6 KPI34849.1 - 0.4 8.7 2.4 0.2 9.8 0.2 1.4 2 0 0 2 2 2 0 Exocyst complex component Sec10 PP2C_C PF07830.8 KPI34849.1 - 2.9 8.0 6.8 0.34 11.0 0.4 2.5 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF572 PF04502.8 KPI34849.1 - 3.9 6.5 14.9 1.6 7.8 6.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) Pyridoxal_deC PF00282.14 KPI34850.1 - 5.7e-16 57.9 0.0 1e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KPI34850.1 - 6.1e-07 28.4 0.0 3e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KPI34850.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family YrhK PF14145.1 KPI34851.1 - 0.0067 16.0 15.8 0.071 12.7 2.6 4.1 3 1 0 3 3 3 2 YrhK-like protein DUF2721 PF11026.3 KPI34851.1 - 0.77 9.4 3.3 0.48 10.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) ATG16 PF08614.6 KPI34852.1 - 3.7e-06 26.9 26.4 3.7e-06 26.9 18.3 4.8 1 1 2 4 4 4 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 KPI34852.1 - 0.011 15.6 11.3 0.011 15.6 7.8 4.4 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KPI34852.1 - 0.017 14.3 18.2 0.056 12.6 2.0 3.8 1 1 3 4 4 4 0 Reovirus sigma C capsid protein Peptidase_M3_N PF08439.5 KPI34852.1 - 1.2 9.2 13.4 0.13 12.2 0.8 4.3 4 0 0 4 4 4 0 Oligopeptidase F DUF3584 PF12128.3 KPI34852.1 - 2 5.6 82.6 0.69 7.1 42.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Imm42 PF15601.1 KPI34852.1 - 2.1 7.7 7.3 0.42 10.0 1.6 2.3 2 0 0 2 2 2 0 Immunity protein 42 DASH_Dam1 PF08653.5 KPI34852.1 - 6.4 6.6 11.3 28 4.5 0.1 4.7 2 2 3 5 5 5 0 DASH complex subunit Dam1 Filament PF00038.16 KPI34852.1 - 8.1 5.8 74.9 3.1 7.1 7.7 2.8 1 1 2 3 3 3 0 Intermediate filament protein AAA_13 PF13166.1 KPI34852.1 - 9.3 4.5 66.1 0.49 8.7 25.5 3.2 1 1 2 3 3 3 0 AAA domain ADIP PF11559.3 KPI34852.1 - 9.9 6.0 88.3 0.12 12.3 16.1 6.1 1 1 5 6 6 6 0 Afadin- and alpha -actinin-Binding PAP_assoc PF03828.14 KPI34854.1 - 9.1e-18 63.9 0.0 2.7e-17 62.4 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KPI34854.1 - 0.033 14.5 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain Aminotran_1_2 PF00155.16 KPI34855.1 - 2e-39 135.5 0.0 2.4e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KPI34855.1 - 9.8e-14 50.8 0.0 1.2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KPI34855.1 - 7e-09 34.4 0.0 9.5e-09 34.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 KPI34855.1 - 2.7e-06 26.7 0.0 3.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KPI34855.1 - 2.9e-05 23.2 0.0 4.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 KPI34855.1 - 0.0013 17.4 0.0 0.0018 17.0 0.0 1.1 1 0 0 1 1 1 1 Allinase Met_gamma_lyase PF06838.6 KPI34855.1 - 0.15 10.2 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Neur_chan_LBD PF02931.18 KPI34856.1 - 0.022 13.9 1.5 0.024 13.8 0.5 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain CoA_transf_3 PF02515.12 KPI34857.1 - 1e-54 184.6 0.1 1.9e-54 183.8 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III adh_short PF00106.20 KPI34858.1 - 5.7e-22 78.4 0.0 8.6e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI34858.1 - 9e-11 41.7 0.4 4.2e-10 39.5 0.3 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KPI34858.1 - 1.3e-08 34.0 0.0 1.8e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KPI34858.1 - 0.00022 20.7 0.0 0.0045 16.4 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KPI34858.1 - 0.022 14.8 0.1 0.035 14.1 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 KPI34858.1 - 0.13 12.1 1.6 0.26 11.1 1.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF955 PF06114.8 KPI34859.1 - 0.061 13.0 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF955) NTP_transf_5 PF14907.1 KPI34859.1 - 0.11 11.8 0.1 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase KxDL PF10241.4 KPI34860.1 - 0.023 14.5 0.1 0.037 13.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF1978 PF09321.5 KPI34860.1 - 0.025 13.9 1.0 0.03 13.7 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) GMC_oxred_N PF00732.14 KPI34861.1 - 1.7e-63 214.5 0.0 2.5e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI34861.1 - 3.2e-38 131.2 0.0 5.9e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KPI34861.1 - 3e-07 29.6 0.0 4.2e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KPI34861.1 - 1.9e-05 23.7 3.3 0.00029 19.8 2.3 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KPI34861.1 - 0.061 12.2 0.1 0.19 10.5 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 KPI34861.1 - 0.062 13.3 0.1 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NCD3G PF07562.9 KPI34861.1 - 0.075 12.7 0.3 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR Lipase_GDSL_2 PF13472.1 KPI34862.1 - 1.6e-06 28.3 0.1 0.00013 22.1 0.1 2.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KPI34862.1 - 4e-05 23.5 0.0 0.0053 16.6 0.0 2.4 1 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Esterase PF00756.15 KPI34863.1 - 0.0013 18.2 0.0 0.006 16.0 0.0 2.1 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KPI34863.1 - 0.0036 16.5 0.1 0.66 9.1 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Acetyltransf_3 PF13302.1 KPI34865.1 - 3.3e-24 85.6 0.0 4.6e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KPI34865.1 - 2.6e-10 40.1 0.1 3.8e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KPI34865.1 - 1.3e-05 25.2 0.0 2.4e-05 24.3 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KPI34865.1 - 0.00013 21.8 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KPI34865.1 - 0.058 13.5 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DENN PF02141.16 KPI34866.1 - 6.3e-22 78.1 0.0 1.6e-21 76.8 0.0 1.8 2 0 0 2 2 2 1 DENN (AEX-3) domain Atg14 PF10186.4 KPI34866.1 - 0.014 14.3 22.8 0.0055 15.6 13.4 2.0 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 uDENN PF03456.13 KPI34866.1 - 0.024 14.5 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 uDENN domain Reo_sigmaC PF04582.7 KPI34866.1 - 0.1 11.7 4.8 0.25 10.4 3.3 1.7 1 0 0 1 1 1 0 Reovirus sigma C capsid protein PCYCGC PF13798.1 KPI34866.1 - 0.23 11.1 3.7 0.52 9.9 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif IncA PF04156.9 KPI34866.1 - 3.7 7.1 23.2 0.14 11.6 11.6 2.0 2 0 0 2 2 2 0 IncA protein Methyltransf_18 PF12847.2 KPI34867.1 - 4.1e-18 66.0 0.0 2.5e-17 63.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI34867.1 - 5.7e-16 58.7 0.0 1e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI34867.1 - 5.3e-14 52.0 0.0 7.2e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI34867.1 - 1.7e-13 50.5 0.0 2.7e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI34867.1 - 2.4e-13 50.2 0.0 7.1e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI34867.1 - 3.8e-13 49.4 0.0 1.1e-12 48.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI34867.1 - 8.3e-11 42.2 0.0 1.8e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KPI34867.1 - 1.5e-07 30.9 0.0 2.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KPI34867.1 - 2.2e-05 24.5 0.0 5.6e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 KPI34867.1 - 3.3e-05 23.1 0.0 5.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KPI34867.1 - 0.0017 19.1 0.0 0.014 16.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 KPI34867.1 - 0.0033 17.1 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KPI34867.1 - 0.005 15.9 0.0 0.0084 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 KPI34867.1 - 0.0092 15.1 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FmrO PF07091.6 KPI34867.1 - 0.014 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) CMAS PF02353.15 KPI34867.1 - 0.038 13.0 0.0 0.075 12.0 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.15 KPI34867.1 - 0.041 12.9 0.0 0.086 11.8 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase TPMT PF05724.6 KPI34867.1 - 0.047 13.1 0.0 0.33 10.3 0.0 2.2 2 1 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.14 KPI34867.1 - 0.047 13.2 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 KPI34867.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB 2OG-FeII_Oxy PF03171.15 KPI34868.1 - 0.024 14.9 0.0 0.39 11.0 0.0 2.2 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KPI34868.1 - 0.084 13.4 0.2 0.53 10.8 0.1 2.1 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF1598 PF07643.6 KPI34869.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) adh_short PF00106.20 KPI34871.1 - 1.4e-26 93.3 0.0 2.3e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI34871.1 - 2.1e-07 30.7 0.0 5.3e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 KR domain hEGF PF12661.2 KPI34872.1 - 3.3 7.9 8.2 0.21 11.7 1.6 2.1 2 0 0 2 2 2 0 Human growth factor-like EGF Pkinase PF00069.20 KPI34873.1 - 4.3e-71 239.1 0.0 6.1e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI34873.1 - 1.5e-31 109.3 0.0 2.3e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KPI34873.1 - 1.4e-11 44.7 2.5 5.3e-11 42.8 1.8 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KPI34873.1 - 5.5e-09 35.4 0.0 1.1e-08 34.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KPI34873.1 - 0.002 17.9 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KPI34873.1 - 0.063 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 KPI34873.1 - 0.067 12.7 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase AMP-binding PF00501.23 KPI34874.1 - 9e-68 228.5 0.0 3.2e-41 141.1 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 KPI34874.1 - 8.5e-10 39.4 0.0 5e-09 36.9 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain zf-CpG_bind_C PF12269.3 KPI34874.1 - 0.18 11.2 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain MFS_1 PF07690.11 KPI34875.1 - 1.1e-38 132.9 21.4 1.6e-38 132.3 14.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily YtpI PF14007.1 KPI34875.1 - 0.91 9.4 4.0 1.5 8.7 0.3 3.1 3 1 0 3 3 3 0 YtpI-like protein SnoaL_4 PF13577.1 KPI34876.1 - 3.5e-21 75.4 0.0 4.4e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.2 KPI34876.1 - 0.021 15.3 0.0 0.041 14.4 0.0 1.5 1 1 0 1 1 1 0 Putative lumazine-binding AIG1 PF04548.11 KPI34877.1 - 1.1e-05 24.6 0.0 1.1e-05 24.6 0.0 2.4 3 0 0 3 3 3 1 AIG1 family MMR_HSR1 PF01926.18 KPI34877.1 - 2e-05 24.5 0.2 8.2e-05 22.5 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase Ribosomal_L14 PF00238.14 KPI34877.1 - 0.075 12.7 0.1 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L14p/L23e AAA_18 PF13238.1 KPI34877.1 - 4.9 7.4 0.0 4.9 7.4 0.0 3.2 2 1 1 3 3 3 0 AAA domain CRC_subunit PF08624.5 KPI34878.1 - 1.4e-53 180.4 0.0 2.3e-53 179.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CobT PF06213.7 KPI34878.1 - 2.4 7.2 8.2 0.48 9.5 3.1 1.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Transp_cyt_pur PF02133.10 KPI34879.1 - 6.3e-139 463.3 40.3 7.2e-139 463.1 27.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TPP_enzyme_N PF02776.13 KPI34880.1 - 5e-40 136.7 0.3 8.9e-40 135.9 0.2 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KPI34880.1 - 4.2e-32 110.7 0.0 1e-31 109.5 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain SR-25 PF10500.4 KPI34882.1 - 0.42 10.0 33.2 0.043 13.2 8.8 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Zn_clus PF00172.13 KPI34883.1 - 0.00023 21.0 9.2 0.00023 21.0 6.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KPI34883.1 - 0.049 13.9 1.9 0.049 13.9 1.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Cyclin PF08613.6 KPI34884.1 - 8.9e-12 45.6 0.0 1.4e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KPI34884.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain MFS_1 PF07690.11 KPI34885.1 - 2.2e-31 108.8 21.2 3.6e-31 108.1 14.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI34885.1 - 6.9e-08 31.4 4.8 6.9e-08 31.4 3.3 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TetR_N PF00440.18 KPI34886.1 - 0.13 11.8 0.1 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family TPP_enzyme_C PF02775.16 KPI34887.1 - 6.4e-15 55.0 1.1 2e-14 53.4 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 KPI34887.1 - 0.16 11.4 4.0 0.24 10.8 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain MFS_1 PF07690.11 KPI34888.1 - 9.6e-36 123.2 35.2 9.6e-36 123.2 24.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Mcp5_PH PF12814.2 KPI34889.1 - 4.7e-08 32.9 0.0 8.7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fungal_trans PF04082.13 KPI34890.1 - 2.1e-30 105.4 0.4 4.8e-30 104.2 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI34890.1 - 4.9e-09 35.9 12.4 8.1e-09 35.2 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_2 PF00891.13 KPI34891.1 - 1.9e-29 102.5 0.0 3.1e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase DUF3046 PF11248.3 KPI34891.1 - 0.018 14.9 0.0 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) TMEM206 PF15122.1 KPI34892.1 - 0.22 10.4 0.0 0.38 9.6 0.0 1.3 1 0 0 1 1 1 0 TMEM206 protein family tRNA-synt_1 PF00133.17 KPI34893.1 - 2e-190 633.7 0.0 3.9e-188 626.2 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Uso1_p115_head PF04869.9 KPI34893.1 - 8.6e-98 326.9 0.0 1.8e-97 325.8 0.0 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Anticodon_1 PF08264.8 KPI34893.1 - 2.7e-25 88.9 0.0 1.2e-23 83.5 0.0 2.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KPI34893.1 - 3.1e-13 49.1 0.3 3e-05 22.8 0.0 3.9 3 1 0 3 3 3 2 tRNA synthetases class I (M) Uso1_p115_C PF04871.8 KPI34893.1 - 2.1e-08 34.1 22.2 2.1e-08 34.1 15.4 4.2 1 1 3 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region HEAT PF02985.17 KPI34893.1 - 0.00073 19.4 2.6 3.2 8.0 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat tRNA-synt_1e PF01406.14 KPI34893.1 - 0.055 12.5 0.0 0.055 12.5 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Pox_A_type_inc PF04508.7 KPI34893.1 - 0.057 13.2 1.9 4.2 7.4 0.1 3.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Reo_sigmaC PF04582.7 KPI34893.1 - 1.8 7.6 3.2 4.2 6.4 0.6 2.1 1 1 0 1 1 1 0 Reovirus sigma C capsid protein adh_short PF00106.20 KPI34894.1 - 1.1e-25 90.5 1.2 1.3e-25 90.2 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI34894.1 - 3.2e-24 86.0 0.0 4.3e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI34894.1 - 1.2e-10 41.4 0.1 1.7e-10 40.8 0.1 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI34894.1 - 0.055 13.4 0.1 0.16 11.9 0.1 1.8 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 KPI34894.1 - 0.065 11.9 0.0 0.089 11.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans_2 PF11951.3 KPI34895.1 - 0.00026 19.7 0.0 0.0021 16.7 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain CorA PF01544.13 KPI34896.1 - 0.003 16.6 5.9 0.096 11.7 0.2 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF1330 PF07045.6 KPI34897.1 - 0.13 12.1 0.2 0.3 10.9 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1330) GTP1_OBG PF01018.17 KPI34898.1 - 1e-34 119.4 3.3 2.1e-28 98.9 2.1 2.9 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.18 KPI34898.1 - 1.8e-09 37.5 0.0 4.1e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF3446 PF11928.3 KPI34898.1 - 5 7.3 18.6 0.13 12.4 6.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Aspzincin_M35 PF14521.1 KPI34899.1 - 0.006 17.0 0.2 0.06 13.8 0.0 2.5 2 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase GlutR_dimer PF00745.15 KPI34899.1 - 0.12 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain AAA PF00004.24 KPI34900.1 - 3.7e-40 137.1 0.1 9.4e-40 135.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KPI34900.1 - 2.7e-05 23.9 0.1 0.00011 21.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KPI34900.1 - 9.2e-05 22.5 0.1 0.011 15.6 0.0 2.9 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KPI34900.1 - 0.00012 21.2 0.1 0.00049 19.2 0.0 2.0 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KPI34900.1 - 0.0007 19.5 1.3 0.0024 17.8 0.0 2.5 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KPI34900.1 - 0.0017 18.4 2.3 0.021 14.9 0.0 2.8 2 1 1 3 3 2 1 AAA domain PhoH PF02562.11 KPI34900.1 - 0.0025 17.1 0.2 0.035 13.3 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.8 KPI34900.1 - 0.0061 15.5 1.0 0.011 14.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 KPI34900.1 - 0.0064 15.6 0.1 0.017 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KPI34900.1 - 0.0083 16.0 0.0 0.028 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KPI34900.1 - 0.012 15.3 0.3 0.036 13.8 0.2 1.8 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 KPI34900.1 - 0.019 14.4 0.1 0.039 13.3 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KPI34900.1 - 0.023 14.0 1.8 0.52 9.6 0.2 2.4 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 KPI34900.1 - 0.037 13.9 0.0 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KPI34900.1 - 0.055 14.2 0.1 0.055 14.2 0.0 3.1 2 2 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KPI34900.1 - 0.13 11.7 6.1 0.32 10.5 0.0 2.8 2 2 0 2 2 2 0 AAA domain Macoilin PF09726.4 KPI34900.1 - 0.64 8.2 7.9 0.91 7.7 5.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Sec63 PF02889.11 KPI34901.1 - 9.8e-42 143.2 0.0 1.1e-40 139.8 0.0 2.1 2 0 0 2 2 2 1 Sec63 Brl domain DnaJ PF00226.26 KPI34901.1 - 7.7e-17 60.7 0.3 1.8e-16 59.6 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain MCC-bdg_PDZ PF10506.4 KPI34901.1 - 0.062 13.1 0.1 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome PALP PF00291.20 KPI34903.1 - 2.4e-36 125.5 0.1 1.6e-24 86.6 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KPI34903.1 - 2.9e-11 42.9 0.0 2.6e-08 33.4 0.0 2.6 2 0 0 2 2 2 2 CBS domain LRR_4 PF12799.2 KPI34904.1 - 0.00016 21.1 4.8 2.5 7.8 0.0 5.4 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KPI34904.1 - 0.0087 15.7 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KPI34904.1 - 0.054 13.2 2.3 40 4.0 0.1 4.7 5 1 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 KPI34904.1 - 0.07 13.2 10.5 0.14 12.2 0.3 5.7 8 0 0 8 8 8 0 Leucine Rich repeat LRR_1 PF00560.28 KPI34904.1 - 0.22 11.6 4.3 1.9 8.8 0.1 4.3 5 0 0 5 5 5 0 Leucine Rich Repeat RRM_1 PF00076.17 KPI34905.1 - 2.8e-12 46.1 0.0 4e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI34905.1 - 5.3e-07 29.5 0.0 8.3e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI34905.1 - 1.8e-06 27.6 0.0 2.5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KPI34905.1 - 0.0005 19.7 0.0 0.00072 19.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DAO PF01266.19 KPI34906.1 - 4.4e-50 170.5 0.1 6.1e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KPI34906.1 - 6.7e-06 25.9 0.2 0.11 12.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KPI34906.1 - 2.5e-05 24.4 0.2 0.00022 21.3 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI34906.1 - 0.00014 20.8 0.2 0.00053 18.9 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KPI34906.1 - 0.0007 19.5 0.0 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KPI34906.1 - 0.00071 18.3 0.1 0.012 14.2 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KPI34906.1 - 0.00094 19.1 1.3 0.13 12.1 0.9 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI34906.1 - 0.0035 16.3 0.1 0.34 9.7 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 KPI34906.1 - 0.019 15.3 0.1 1 9.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KPI34906.1 - 0.026 14.6 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KPI34906.1 - 0.043 13.8 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF336 PF03928.9 KPI34906.1 - 0.07 12.9 0.8 0.18 11.5 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF336) Peptidase_S28 PF05577.7 KPI34908.1 - 1.7e-32 112.5 0.0 2.3e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 KPI34908.1 - 4.7e-06 26.6 0.1 1.2e-05 25.3 0.1 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI34908.1 - 8.8e-06 25.0 0.1 2.4e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KPI34908.1 - 0.0004 20.0 0.0 0.00059 19.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KPI34908.1 - 0.0037 16.8 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI34908.1 - 0.034 13.8 0.1 0.089 12.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2920 PF11144.3 KPI34908.1 - 0.043 12.8 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Acetyltransf_1 PF00583.19 KPI34909.1 - 2.3e-12 46.7 0.0 7.6e-12 45.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KPI34909.1 - 2.4e-07 30.3 0.1 1.9e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 KPI34909.1 - 2.4e-06 27.6 0.2 5.2e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI34909.1 - 3.7e-06 27.0 0.0 1.1e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KPI34909.1 - 0.0031 17.6 0.0 0.0049 17.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KPI34909.1 - 0.0054 16.6 0.0 0.017 15.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KPI34909.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 KPI34909.1 - 0.034 13.9 0.1 0.066 13.0 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Macoilin PF09726.4 KPI34910.1 - 0.018 13.3 0.0 0.043 12.1 0.0 1.5 1 1 0 1 1 1 0 Transmembrane protein Lin-8 PF03353.10 KPI34910.1 - 0.025 13.8 1.6 0.064 12.5 1.1 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2514 PF10721.4 KPI34910.1 - 0.26 10.9 7.6 0.64 9.6 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) ABM PF03992.11 KPI34911.1 - 1e-07 31.8 0.0 2.5e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase p450 PF00067.17 KPI34912.1 - 1.8e-58 198.1 0.0 2.4e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cpn60_TCP1 PF00118.19 KPI34913.1 - 9.7e-143 476.2 4.6 1.1e-142 476.0 3.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSDR_N_2 PF13588.1 KPI34913.1 - 0.077 12.7 0.1 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Fork_head PF00250.13 KPI34914.1 - 6.3e-14 51.7 0.0 1.3e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KPI34914.1 - 1.3e-05 25.2 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain Prefoldin_2 PF01920.15 KPI34915.1 - 5.9e-17 61.3 13.0 8.4e-17 60.8 9.0 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 KPI34915.1 - 0.0014 18.3 1.1 0.0014 18.3 0.7 1.5 1 1 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 KPI34915.1 - 0.0028 17.2 16.3 0.0069 16.0 11.3 1.6 1 1 0 1 1 1 1 IncA protein DUF484 PF04340.7 KPI34915.1 - 0.035 13.5 0.2 0.035 13.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF484 Prefoldin PF02996.12 KPI34915.1 - 0.038 13.6 12.6 0.043 13.4 1.6 2.5 1 1 2 3 3 3 0 Prefoldin subunit MscS_porin PF12795.2 KPI34915.1 - 0.046 13.0 19.0 0.15 11.3 2.8 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain TPR_5 PF12688.2 KPI34915.1 - 0.059 13.4 0.3 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Tetratrico peptide repeat BLOC1_2 PF10046.4 KPI34915.1 - 0.13 12.3 5.4 3.1 7.9 0.7 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMEM206 PF15122.1 KPI34915.1 - 0.15 10.9 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 TMEM206 protein family DUF4051 PF13260.1 KPI34915.1 - 0.21 10.9 0.4 0.47 9.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Ded_cyto PF06920.8 KPI34915.1 - 0.22 10.7 7.6 0.59 9.4 1.1 2.0 2 0 0 2 2 2 0 Dedicator of cytokinesis Tropomyosin_1 PF12718.2 KPI34915.1 - 0.48 10.2 14.4 0.51 10.1 1.5 2.2 2 0 0 2 2 2 0 Tropomyosin like CCDC-167 PF15188.1 KPI34915.1 - 0.88 9.5 4.1 5.6 6.9 0.2 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 FlaC_arch PF05377.6 KPI34915.1 - 0.95 9.4 4.2 5.6 6.9 0.1 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 KPI34915.1 - 1.1 9.5 9.4 5.6 7.2 1.6 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 KPI34915.1 - 1.2 9.5 8.5 6.1 7.2 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Spc24 PF08286.6 KPI34915.1 - 1.5 8.5 11.9 2.4 7.8 1.4 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Gon7 PF08738.5 KPI34915.1 - 1.5 8.8 6.8 6.2 6.8 1.3 2.2 2 0 0 2 2 2 0 Gon7 family DUF848 PF05852.6 KPI34915.1 - 1.6 8.5 9.3 4.2 7.1 0.3 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Fib_alpha PF08702.5 KPI34915.1 - 2.1 8.4 9.6 11 6.1 6.6 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 KPI34915.1 - 2.1 8.0 12.9 1.9 8.2 2.6 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Sas10_Utp3 PF04000.10 KPI34915.1 - 2.5 8.3 6.0 14 5.9 1.5 2.2 2 0 0 2 2 2 0 Sas10/Utp3/C1D family SbcD_C PF12320.3 KPI34915.1 - 3.4 7.7 6.6 1.1 9.2 0.4 2.2 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain IFT57 PF10498.4 KPI34915.1 - 3.6 6.2 12.0 16 4.1 8.3 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Pol_alpha_B_N PF08418.5 KPI34915.1 - 4 6.9 5.8 0.83 9.1 1.9 1.5 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Spc7 PF08317.6 KPI34915.1 - 4.7 5.7 11.0 12 4.4 7.6 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Snf7 PF03357.16 KPI34915.1 - 5 6.4 12.2 1.9 7.8 2.8 2.1 2 0 0 2 2 2 0 Snf7 Dzip-like_N PF13815.1 KPI34915.1 - 7 6.4 11.2 4.5 7.1 2.0 2.2 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF4349 PF14257.1 KPI34915.1 - 7.1 5.7 12.5 0.18 11.0 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF3571 PF12095.3 KPI34915.1 - 7.3 6.8 7.1 40 4.5 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3571) SF-assemblin PF06705.6 KPI34915.1 - 7.7 5.5 10.3 88 2.1 6.7 2.0 1 1 0 1 1 1 0 SF-assemblin/beta giardin FlxA PF14282.1 KPI34915.1 - 9 6.2 20.0 3 7.8 3.6 2.1 2 0 0 2 2 2 0 FlxA-like protein AMP-binding PF00501.23 KPI34916.1 - 7.1e-63 212.4 0.0 8.9e-63 212.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI34916.1 - 1.4e-11 45.1 0.0 3e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CC PF04942.9 KPI34917.1 - 0.0017 18.2 0.4 0.0017 18.2 0.3 2.3 2 0 0 2 2 2 1 CC domain Hairy_orange PF07527.8 KPI34918.1 - 0.013 15.2 0.1 0.026 14.2 0.1 1.5 1 0 0 1 1 1 0 Hairy Orange B5 PF03484.10 KPI34919.1 - 0.0041 16.9 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase B5 domain Mito_carr PF00153.22 KPI34921.1 - 1.2e-72 239.7 6.9 8.4e-24 83.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein IBR PF01485.16 KPI34922.1 - 4.7e-21 74.4 41.1 2.3e-10 40.1 11.1 4.5 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 KPI34922.1 - 1.2e-06 28.4 4.0 1.2e-06 28.4 2.8 4.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KPI34922.1 - 2.4e-05 24.0 2.2 2.4e-05 24.0 1.5 3.6 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 KPI34922.1 - 0.00024 20.7 34.0 0.00048 19.7 2.1 4.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI34922.1 - 0.00026 20.6 4.9 0.00026 20.6 3.4 3.6 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KPI34922.1 - 0.021 14.5 0.4 0.021 14.5 0.3 3.4 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KPI34922.1 - 0.071 13.0 0.3 0.071 13.0 0.2 5.0 5 1 0 5 5 5 0 zinc finger of C3HC4-type, RING FRQ PF09421.5 KPI34923.1 - 1.9e-90 304.1 46.7 2.9e-87 293.5 21.4 4.8 3 1 0 3 3 3 3 Frequency clock protein FAD_binding_3 PF01494.14 KPI34927.1 - 5.8e-05 22.3 1.2 0.22 10.5 0.2 2.4 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KPI34927.1 - 0.0014 17.6 0.1 0.0057 15.5 0.0 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI34927.1 - 0.011 15.7 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KPI34927.1 - 0.012 16.0 0.0 0.034 14.5 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AAA PF00004.24 KPI34928.1 - 3.1e-42 143.9 0.0 5.1e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KPI34928.1 - 4.5e-29 100.1 0.0 7e-28 96.3 0.0 2.8 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 KPI34928.1 - 1.6e-20 72.7 5.9 2.1e-20 72.3 2.6 2.3 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 KPI34928.1 - 3.9e-06 27.6 0.0 1.5e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KPI34928.1 - 1.1e-05 24.5 0.0 2.1e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KPI34928.1 - 1.5e-05 24.7 0.0 9e-05 22.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KPI34928.1 - 1.6e-05 24.9 0.1 0.006 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KPI34928.1 - 1.6e-05 25.0 0.1 0.0014 18.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KPI34928.1 - 3.2e-05 23.4 0.0 6.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KPI34928.1 - 3.5e-05 22.7 0.0 6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 KPI34928.1 - 5.3e-05 23.3 0.0 0.0096 16.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 KPI34928.1 - 5.6e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KPI34928.1 - 5.6e-05 22.6 0.3 0.15 11.4 0.1 3.3 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 KPI34928.1 - 0.00018 21.5 0.0 0.0017 18.3 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 KPI34928.1 - 0.00029 19.8 0.0 0.0014 17.6 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 KPI34928.1 - 0.0005 19.9 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Torsin PF06309.6 KPI34928.1 - 0.0013 18.6 0.1 0.073 12.9 0.0 2.3 2 0 0 2 2 2 1 Torsin AAA_18 PF13238.1 KPI34928.1 - 0.0078 16.5 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KPI34928.1 - 0.0092 15.5 0.4 0.03 13.8 0.0 2.1 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 KPI34928.1 - 0.011 15.4 0.3 0.32 10.6 0.0 2.7 2 1 1 3 3 3 0 Archaeal ATPase Mg_chelatase PF01078.16 KPI34928.1 - 0.02 14.0 0.0 0.065 12.3 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KPI34928.1 - 0.025 13.7 0.1 0.16 11.0 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin AAA_19 PF13245.1 KPI34928.1 - 0.025 14.3 0.0 0.07 12.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 KPI34928.1 - 0.026 14.1 0.0 0.65 9.6 0.0 2.3 1 1 1 2 2 2 0 NACHT domain ResIII PF04851.10 KPI34928.1 - 0.035 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 KPI34928.1 - 0.04 13.1 0.0 0.094 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 KPI34928.1 - 0.048 12.5 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Peptidase_M28 PF04389.12 KPI34928.1 - 0.1 12.3 0.0 0.53 9.9 0.0 2.0 2 0 0 2 2 2 0 Peptidase family M28 W2 PF02020.13 KPI34929.1 - 3.1e-15 55.8 1.8 7.3e-15 54.6 1.2 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 KPI34929.1 - 9.8e-08 31.1 5.2 0.0054 16.1 0.1 4.3 1 1 3 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 KPI34929.1 - 1e-07 31.5 0.0 1.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KPI34929.1 - 0.0016 18.5 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KPI34929.1 - 0.0044 16.5 6.3 1.1 8.9 4.4 2.8 1 1 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase Vpu PF00558.14 KPI34929.1 - 0.19 11.3 3.9 0.43 10.1 2.7 1.6 1 0 0 1 1 1 0 Vpu protein Sugar_tr PF00083.19 KPI34930.1 - 3.3e-70 236.8 20.3 2.8e-67 227.2 14.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI34930.1 - 8.1e-10 37.9 11.8 8.1e-10 37.9 8.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KPI34931.1 - 1.1e-124 416.6 25.7 1.2e-124 416.4 17.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Gram_pos_anchor PF00746.16 KPI34931.1 - 0.11 12.3 0.7 0.44 10.4 0.5 2.2 1 0 0 1 1 1 0 Gram positive anchor Myb_DNA-bind_6 PF13921.1 KPI34932.1 - 8.3e-09 35.4 1.8 0.0018 18.3 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KPI34932.1 - 4.2e-08 33.1 1.0 0.0094 15.9 0.2 3.0 2 1 0 2 2 2 2 Myb-like DNA-binding domain Scytalone_dh PF02982.9 KPI34932.1 - 0.012 15.1 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Scytalone dehydratase p450 PF00067.17 KPI34933.1 - 2.3e-48 164.9 0.0 2.9e-34 118.3 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 DUF3974 PF13120.1 KPI34933.1 - 0.091 12.5 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) SSF PF00474.12 KPI34934.1 - 3.1e-09 35.9 16.5 6.2e-09 34.9 11.5 1.6 1 1 0 1 1 1 1 Sodium:solute symporter family DUF872 PF05915.7 KPI34934.1 - 1.7 8.5 5.6 0.98 9.2 0.4 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) adh_short PF00106.20 KPI34935.1 - 1.2e-12 48.0 0.0 1.7e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 KPI34935.1 - 0.053 13.3 0.2 0.097 12.4 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 KPI34935.1 - 0.065 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KPI34935.1 - 0.1 12.2 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA PF00004.24 KPI34936.1 - 6.7e-38 129.8 0.0 1.1e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KPI34936.1 - 6.4e-06 26.3 0.1 4.6e-05 23.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KPI34936.1 - 3e-05 23.1 0.0 6.8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Vps4_C PF09336.5 KPI34936.1 - 0.00011 21.9 0.0 0.00076 19.3 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.9 KPI34936.1 - 0.00056 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KPI34936.1 - 0.0006 19.5 0.0 0.0016 18.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) p47_phox_C PF08944.6 KPI34936.1 - 0.0011 19.0 2.5 0.0011 19.0 1.7 4.2 4 1 1 5 5 3 1 NADPH oxidase subunit p47Phox, C terminal domain IstB_IS21 PF01695.12 KPI34936.1 - 0.0012 18.3 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KPI34936.1 - 0.0016 17.2 0.0 0.0026 16.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 KPI34936.1 - 0.0017 18.3 0.9 0.014 15.3 0.1 2.8 3 1 0 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 KPI34936.1 - 0.0037 16.4 0.1 0.0075 15.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KPI34936.1 - 0.0062 16.4 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KPI34936.1 - 0.007 16.0 0.1 0.027 14.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 KPI34936.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KPI34936.1 - 0.021 14.2 0.3 0.18 11.1 0.1 2.5 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 KPI34936.1 - 0.029 15.1 0.1 0.077 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 KPI34936.1 - 0.032 13.1 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 KPI34936.1 - 0.035 14.0 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KPI34936.1 - 0.053 13.1 0.0 0.22 11.1 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Guanylate_kin PF00625.16 KPI34936.1 - 0.054 12.9 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase AAA_28 PF13521.1 KPI34936.1 - 0.06 13.3 1.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 KPI34936.1 - 0.15 11.2 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 KPI34936.1 - 0.26 10.7 0.0 0.7 9.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Peptidase_C14 PF00656.17 KPI34938.1 - 2.2e-72 243.7 0.0 2.9e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KPI34938.1 - 0.027 14.3 0.4 0.14 12.0 0.0 2.5 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain Aldedh PF00171.17 KPI34939.1 - 1.5e-14 53.2 5.3 1.6e-12 46.5 1.3 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family 2OG-FeII_Oxy PF03171.15 KPI34940.1 - 2.7e-12 46.8 0.0 4.1e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KPI34940.1 - 9.2e-10 39.0 0.0 1.6e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Pil1 PF13805.1 KPI34942.1 - 2.1e-99 332.0 2.3 2.1e-99 332.0 1.6 1.7 2 0 0 2 2 2 1 Eisosome component PIL1 DUF2508 PF10704.4 KPI34942.1 - 0.33 11.1 6.7 4.8 7.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) Seryl_tRNA_N PF02403.17 KPI34942.1 - 1.7 8.7 8.4 0.97 9.4 3.6 2.2 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 KPI34942.1 - 1.9 7.4 8.4 0.66 8.9 3.6 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 2H-phosphodiest PF08975.5 KPI34943.1 - 1e-22 80.1 0.0 1.9e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1868) Mito_carr PF00153.22 KPI34944.1 - 3e-64 212.7 9.7 9.6e-26 89.3 0.3 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein 4HBT_3 PF13622.1 KPI34945.1 - 2.2e-46 158.6 8.8 1.1e-45 156.3 6.1 1.8 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KPI34945.1 - 3e-22 78.6 0.1 2.6e-12 46.5 0.0 4.5 4 1 0 4 4 4 3 Acyl-CoA thioesterase Succ_CoA_lig PF13607.1 KPI34945.1 - 0.05 13.2 0.0 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain CoA_trans PF01144.18 KPI34946.1 - 1.1e-103 345.0 2.6 1.8e-62 210.3 0.8 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DnaJ PF00226.26 KPI34947.1 - 9.8e-10 38.0 0.7 1.8e-09 37.2 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain Inhibitor_I53 PF11714.3 KPI34947.1 - 0.11 12.4 0.1 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Arginase PF00491.16 KPI34948.1 - 2.6e-68 230.3 0.2 4.3e-68 229.6 0.1 1.3 1 0 0 1 1 1 1 Arginase family DUF3659 PF12396.3 KPI34948.1 - 2e-11 43.3 1.9 4.4e-11 42.2 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) FIVAR PF07554.8 KPI34948.1 - 1.2 9.4 4.4 1.6 9.0 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised Sugar-binding Domain ANTAR PF03861.9 KPI34949.1 - 0.13 11.8 0.2 2.7 7.6 0.0 2.5 2 0 0 2 2 2 0 ANTAR domain RRM_6 PF14259.1 KPI34949.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) 2OG-FeII_Oxy_3 PF13640.1 KPI34950.1 - 9.7e-11 42.0 0.0 1.5e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KPI34950.1 - 4.2e-06 26.3 0.3 8.1e-06 25.3 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF367 PF04034.8 KPI34951.1 - 1.3e-23 83.0 1.1 1.4e-17 63.5 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF367) RLI PF04068.10 KPI34951.1 - 8.6e-10 38.0 0.1 3.4e-09 36.1 0.2 2.0 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI LcrG PF07216.7 KPI34951.1 - 0.15 12.0 2.6 7.4 6.6 0.3 3.1 3 0 0 3 3 3 0 LcrG protein zf-H2C2 PF09337.5 KPI34952.1 - 1e-20 72.8 4.4 1.6e-20 72.1 3.0 1.3 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 KPI34952.1 - 1.6e-05 24.8 0.0 3.8e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KPI34952.1 - 0.00048 20.3 0.0 0.00083 19.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KPI34952.1 - 0.0015 18.4 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KPI34952.1 - 0.032 14.3 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KPI34952.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ECR1_N PF14382.1 KPI34953.1 - 1e-11 43.9 0.0 2.9e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KPI34953.1 - 0.00095 19.0 0.0 0.021 14.7 0.0 2.5 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Pmp3 PF01679.12 KPI34955.1 - 7.7e-13 47.9 4.2 1.1e-12 47.3 2.9 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PsaD PF02531.11 KPI34955.1 - 0.043 13.0 0.1 7.6 5.7 0.1 2.3 2 0 0 2 2 2 0 PsaD CAP59_mtransfer PF11735.3 KPI34956.1 - 3.8e-76 255.5 0.0 5.1e-76 255.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 UPF0203 PF05254.7 KPI34957.1 - 2.6e-28 97.6 1.1 2.9e-28 97.4 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 KPI34957.1 - 0.0014 18.5 0.4 0.0032 17.4 0.3 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KPI34957.1 - 0.0018 17.9 1.9 0.066 13.0 0.1 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like DUF4179 PF13786.1 KPI34957.1 - 0.016 15.4 0.0 0.019 15.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) UCR_hinge PF02320.11 KPI34957.1 - 0.03 14.2 0.7 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Ribosomal_L18e PF00828.14 KPI34959.1 - 1.7e-25 89.8 0.1 1.7e-25 89.8 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 GatB_N PF02934.10 KPI34960.1 - 3.3e-96 321.5 0.0 4.2e-96 321.2 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KPI34960.1 - 6.8e-21 74.5 0.1 1.1e-20 73.8 0.1 1.3 1 0 0 1 1 1 1 GatB domain COG2 PF06148.6 KPI34961.1 - 2.1e-23 82.6 0.0 4.2e-23 81.6 0.0 1.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 KPI34961.1 - 4.3e-06 26.4 0.0 1.4e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Nop14 PF04147.7 KPI34961.1 - 0.063 11.1 0.8 0.071 11.0 0.5 1.2 1 0 0 1 1 1 0 Nop14-like family COG5 PF10392.4 KPI34961.1 - 0.094 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 TORC_M PF12885.2 KPI34961.1 - 0.24 11.1 2.5 0.42 10.3 1.7 1.3 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Transp_cyt_pur PF02133.10 KPI34962.1 - 2.4e-100 336.1 34.7 2.8e-100 335.9 24.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin UPF0239 PF06783.6 KPI34962.1 - 0.14 12.1 0.0 0.45 10.4 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Choline_transpo PF04515.7 KPI34964.1 - 4.2e-12 45.4 16.0 4.2e-12 45.4 11.1 3.1 3 0 0 3 3 3 2 Plasma-membrane choline transporter Ku PF02735.11 KPI34965.1 - 1.1e-24 86.9 0.0 2.1e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KPI34965.1 - 7.7e-18 64.7 0.0 2.1e-17 63.3 0.0 1.7 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.1 KPI34965.1 - 9.8e-08 32.2 0.0 3.1e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_PK_bind PF08785.6 KPI34965.1 - 2.4e-06 27.4 0.0 5.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like Beta-lactamase PF00144.19 KPI34966.1 - 5.4e-54 183.4 0.0 7.3e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase DUF241 PF03087.9 KPI34967.1 - 0.14 11.6 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function FAD-oxidase_C PF02913.14 KPI34968.1 - 2e-56 191.0 0.0 3.4e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KPI34968.1 - 3.2e-38 130.3 0.2 5.3e-38 129.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NPV_P10 PF05531.7 KPI34969.1 - 0.032 14.4 0.1 0.049 13.8 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Syntaxin PF00804.20 KPI34969.1 - 0.045 13.9 0.2 0.063 13.4 0.1 1.2 1 0 0 1 1 1 0 Syntaxin Uds1 PF15456.1 KPI34969.1 - 0.046 13.7 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Up-regulated During Septation Laminin_II PF06009.7 KPI34969.1 - 0.059 13.1 0.1 0.088 12.5 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain II IncA PF04156.9 KPI34969.1 - 1.8 8.0 7.1 20 4.7 0.0 2.2 2 0 0 2 2 2 0 IncA protein ParA PF10609.4 KPI34970.1 - 2.8e-35 120.0 0.8 6.6e-35 118.8 0.6 1.7 1 1 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KPI34970.1 - 3.8e-13 49.2 0.0 8.3e-13 48.1 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KPI34970.1 - 5.5e-07 29.6 0.0 2.2e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 KPI34970.1 - 9.7e-07 28.1 0.0 1.5e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 KPI34970.1 - 2.2e-05 23.6 0.2 4.2e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.1 KPI34970.1 - 0.00081 18.8 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 KPI34970.1 - 0.0014 17.4 0.2 0.0022 16.7 0.1 1.2 1 0 0 1 1 1 1 ArgK protein SRP54 PF00448.17 KPI34970.1 - 0.002 17.5 0.0 0.46 9.8 0.0 2.2 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_26 PF13500.1 KPI34970.1 - 0.0062 16.1 1.0 0.45 10.0 0.4 2.2 2 0 0 2 2 2 1 AAA domain YhjQ PF06564.7 KPI34970.1 - 0.0075 15.6 0.2 0.018 14.4 0.1 1.5 2 0 0 2 2 2 1 YhjQ protein APS_kinase PF01583.15 KPI34970.1 - 0.0094 15.6 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Fer4_NifH PF00142.13 KPI34970.1 - 0.071 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Alpha_GJ PF03229.8 KPI34970.1 - 0.23 11.8 2.8 0.13 12.5 0.5 1.6 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF258 PF03193.11 KPI34970.1 - 0.23 10.6 2.2 0.23 10.6 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF917 PF06032.7 KPI34971.1 - 5.2e-100 334.4 0.0 1.1e-99 333.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 KPI34971.1 - 1.5e-47 162.0 8.9 1.1e-44 152.7 3.3 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KPI34971.1 - 4e-31 107.8 7.1 1.6e-28 99.4 0.0 3.8 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 KPI34971.1 - 0.00016 20.1 1.6 0.11 10.8 0.1 2.3 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 KPI34971.1 - 0.00055 19.3 0.0 0.0048 16.2 0.1 2.3 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family CorA PF01544.13 KPI34972.1 - 6.6e-09 35.2 0.9 1.1e-08 34.4 0.6 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RPW8 PF05659.6 KPI34972.1 - 0.11 11.9 0.1 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Pyr_redox_3 PF13738.1 KPI34973.1 - 1.2e-22 81.0 0.0 3e-22 79.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI34973.1 - 3.6e-20 71.6 0.0 2.5e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI34973.1 - 9.5e-11 41.5 0.0 2.2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI34973.1 - 3.5e-07 29.4 0.0 4.2e-05 22.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KPI34973.1 - 0.001 18.8 0.7 0.031 14.0 0.0 3.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KPI34973.1 - 0.028 13.4 0.0 7.3 5.5 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Ras PF00071.17 KPI34974.1 - 6.6e-51 171.8 0.1 1.7e-50 170.5 0.1 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KPI34974.1 - 1.1e-16 61.4 0.0 2.9e-16 60.0 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KPI34974.1 - 2.8e-12 46.2 0.0 9.3e-11 41.2 0.1 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KPI34974.1 - 1.8e-09 37.3 0.0 3.2e-09 36.4 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KPI34974.1 - 1.5e-06 27.5 0.0 2.7e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KPI34974.1 - 0.0002 21.2 0.0 0.00038 20.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase MecA_N PF05223.6 KPI34974.1 - 1.1 9.3 3.9 22 5.1 0.0 3.0 2 1 1 3 3 3 0 NTF2-like N-terminal transpeptidase domain UPF0047 PF01894.12 KPI34977.1 - 5.1e-43 145.6 0.0 5.8e-43 145.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 MFS_1 PF07690.11 KPI34978.1 - 2.7e-05 23.0 31.3 2.7e-05 23.0 21.7 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KPI34978.1 - 0.066 11.3 11.2 0.3 9.2 7.4 2.2 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) zf-CHCC PF10276.4 KPI34979.1 - 1.6e-13 50.2 2.6 2.6e-13 49.5 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger domain R3H PF01424.17 KPI34980.1 - 8.6e-11 41.3 0.1 1.6e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 KPI34980.1 - 7.1e-08 32.3 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KPI34980.1 - 5e-06 26.0 0.0 1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI34980.1 - 0.0046 16.7 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 KPI34980.1 - 0.086 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 HET PF06985.6 KPI34981.1 - 6.6e-26 91.1 0.0 1.7e-25 89.7 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FliS PF02561.9 KPI34981.1 - 0.031 14.1 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Flagellar protein FliS tRNA-synt_2 PF00152.15 KPI34982.1 - 2.7e-73 246.6 0.4 2.7e-73 246.6 0.3 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KPI34982.1 - 6.6e-07 29.0 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain TEBP_beta PF07404.6 KPI34982.1 - 5.7 5.9 12.4 4.2 6.3 6.8 1.9 2 0 0 2 2 2 0 Telomere-binding protein beta subunit (TEBP beta) HET PF06985.6 KPI34983.1 - 6.5e-33 113.8 0.2 1.2e-32 112.9 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.1 KPI34984.1 - 6.1e-35 121.1 0.1 7.4e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI34984.1 - 5.3e-29 101.2 0.1 7.5e-29 100.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI34984.1 - 6.7e-10 38.9 0.2 1e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI34984.1 - 3e-06 26.8 0.1 4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KPI34984.1 - 0.0027 17.4 0.4 0.0074 16.0 0.3 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AA_permease PF00324.16 KPI34986.1 - 6.7e-139 463.2 46.8 8.3e-139 462.9 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI34986.1 - 6.9e-36 123.6 53.3 8.4e-36 123.4 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease PBP1_TM PF14812.1 KPI34987.1 - 0.057 13.7 0.3 0.057 13.7 0.2 3.1 2 1 2 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Med13_C PF06333.7 KPI34987.1 - 0.066 11.7 2.9 0.08 11.4 2.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Aldo_ket_red PF00248.16 KPI34988.1 - 5.8e-14 51.5 0.0 2.2e-13 49.7 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KPI34989.1 - 7.3e-46 156.2 0.0 9.8e-46 155.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Catalase PF00199.14 KPI34990.1 - 2.2e-58 197.7 0.0 2.7e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Catalase MFS_1 PF07690.11 KPI34991.1 - 2.4e-07 29.7 14.7 2.8e-07 29.5 9.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KPI34993.1 - 1.6e-16 60.0 2.6 1.7e-16 59.8 0.6 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Col_cuticle_N PF01484.12 KPI34993.1 - 0.074 12.7 0.1 7.4 6.3 0.0 2.7 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Raffinose_syn PF05691.7 KPI34994.1 - 1.3e-46 158.5 5.0 1.9e-44 151.3 2.8 3.2 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 KPI34994.1 - 7e-07 28.2 0.8 1.1e-06 27.5 0.5 1.2 1 0 0 1 1 1 1 Melibiase DAO PF01266.19 KPI34995.1 - 5.1e-46 157.2 0.0 6.3e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI34995.1 - 4.5e-06 26.5 0.2 1.1e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KPI34995.1 - 0.00055 20.0 0.0 0.00079 19.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KPI34995.1 - 0.0086 15.1 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI34995.1 - 0.013 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KPI34995.1 - 0.015 14.4 0.2 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KPI34995.1 - 0.032 12.7 0.2 0.046 12.1 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.13 KPI34995.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 KPI34995.1 - 0.074 12.1 0.1 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 KPI34995.1 - 0.11 11.3 1.0 0.2 10.4 0.7 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 KPI34995.1 - 0.11 12.2 0.1 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 KPI34995.1 - 0.11 12.9 0.3 0.21 12.0 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HSF_DNA-bind PF00447.12 KPI34997.1 - 4.1e-29 100.7 0.4 4.1e-29 100.7 0.3 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding Histone PF00125.19 KPI34998.1 - 4.3e-22 78.0 0.0 5.7e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KPI34998.1 - 4.7e-05 23.3 0.0 7.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PX PF00787.19 KPI34999.1 - 3.5e-15 55.7 0.0 1e-14 54.2 0.0 1.8 2 0 0 2 2 2 1 PX domain SNARE PF05739.14 KPI34999.1 - 1.3e-08 34.4 6.5 3.1e-08 33.1 4.5 1.7 1 0 0 1 1 1 1 SNARE domain BCIP PF13862.1 KPI34999.1 - 0.024 14.1 0.2 0.057 12.9 0.2 1.6 1 0 0 1 1 1 0 p21-C-terminal region-binding protein IncA PF04156.9 KPI34999.1 - 1.5 8.3 9.7 0.4 10.2 2.5 2.1 1 1 1 2 2 2 0 IncA protein Fungal_trans PF04082.13 KPI35000.1 - 2.6e-21 75.6 0.6 4.1e-21 75.0 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KPI35001.1 - 2.1e-11 43.2 0.3 3.5e-11 42.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI35001.1 - 3.5e-06 26.7 8.8 7e-06 25.8 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4440 PF14534.1 KPI35004.1 - 0.00093 19.3 0.0 0.0012 19.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Lumazine_bd_2 PF12893.2 KPI35004.1 - 0.014 15.8 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 Putative lumazine-binding DUF676 PF05057.9 KPI35005.1 - 6.5e-07 28.8 0.0 1.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KPI35005.1 - 1.2e-05 25.0 0.0 2.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI35005.1 - 4.4e-05 23.4 0.0 9.6e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KPI35005.1 - 9.9e-05 22.0 0.0 0.00023 20.8 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 KPI35005.1 - 0.008 15.7 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Toxin_43 PF15604.1 KPI35005.1 - 0.065 13.2 8.2 0.12 12.4 5.7 1.3 1 0 0 1 1 1 0 Putative toxin 43 Thioesterase PF00975.15 KPI35005.1 - 0.31 11.2 2.5 0.99 9.5 0.0 2.5 3 0 0 3 3 3 0 Thioesterase domain DUF1168 PF06658.7 KPI35005.1 - 4.4 6.8 16.2 7.3 6.1 11.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Ifi-6-16 PF06140.8 KPI35006.1 - 3.4e-06 26.7 21.8 3.4e-06 26.7 15.1 2.0 1 1 1 2 2 2 1 Interferon-induced 6-16 family ADH_N PF08240.7 KPI35008.1 - 4.4e-21 74.6 1.9 8.7e-21 73.7 1.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI35008.1 - 3.7e-18 65.3 0.1 8e-18 64.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI35008.1 - 7.6e-05 23.5 0.0 0.00013 22.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 KPI35008.1 - 0.0071 16.4 0.0 0.017 15.2 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KPI35009.1 - 5.3e-13 49.2 0.7 9.5e-13 48.4 0.5 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KPI35009.1 - 0.00014 21.3 0.1 0.00045 19.7 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI35009.1 - 0.001 19.0 0.1 0.02 14.8 0.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KPI35009.1 - 0.0015 18.1 0.1 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KPI35009.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Rcd1 PF04078.8 KPI35010.1 - 4.6e-124 412.4 0.2 1.2e-123 411.0 0.1 1.6 1 1 0 1 1 1 1 Cell differentiation family, Rcd1-like DUF1295 PF06966.7 KPI35011.1 - 4.7e-55 186.4 0.0 7.2e-55 185.8 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 KPI35011.1 - 4.5e-07 29.7 0.4 3.8e-06 26.7 0.1 2.5 2 1 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 KPI35011.1 - 0.00037 20.6 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KPI35011.1 - 0.0079 16.2 1.0 0.13 12.4 0.0 3.1 3 1 0 3 3 3 1 Phospholipid methyltransferase HlyIII PF03006.15 KPI35011.1 - 2.6 7.3 7.5 0.22 10.9 1.8 1.7 2 0 0 2 2 2 0 Haemolysin-III related BPD_transp_2 PF02653.11 KPI35011.1 - 3.9 6.3 9.2 0.32 9.9 0.5 2.5 2 1 1 3 3 3 0 Branched-chain amino acid transport system / permease component PIG-P PF08510.7 KPI35011.1 - 9.2 5.9 6.7 0.82 9.3 0.0 2.5 3 0 0 3 3 3 0 PIG-P DJ-1_PfpI PF01965.19 KPI35012.1 - 4e-16 58.8 0.1 8.4e-16 57.7 0.1 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KPI35012.1 - 1.2e-05 24.7 0.0 2.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family adh_short PF00106.20 KPI35013.1 - 1.8e-21 76.8 0.8 1.6e-20 73.7 0.3 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI35013.1 - 2.9e-12 46.9 0.2 1.1e-06 28.6 0.1 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI35013.1 - 8.1e-11 41.9 0.5 1.2e-10 41.3 0.3 1.1 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KPI35013.1 - 0.00015 20.8 0.2 0.00021 20.4 0.2 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KPI35013.1 - 0.0003 20.8 0.2 0.0013 18.7 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI35013.1 - 0.00046 19.6 0.0 0.00075 18.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KPI35013.1 - 0.052 12.4 0.1 0.074 11.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KPI35013.1 - 0.12 11.0 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans_2 PF11951.3 KPI35014.1 - 2.4e-43 148.2 1.5 3.3e-43 147.7 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Baculo_FP PF03258.9 KPI35014.1 - 0.035 13.1 0.1 3.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Baculovirus FP protein Fungal_trans PF04082.13 KPI35015.1 - 9.5e-17 60.7 0.1 2e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI35015.1 - 1.5e-05 24.7 13.6 3.1e-05 23.7 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 KPI35016.1 - 3.8e-13 49.9 0.0 1.2e-12 48.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI35016.1 - 1.8e-12 46.8 0.0 3.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KPI35016.1 - 1.1e-06 27.1 0.0 0.00066 17.9 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Proteasome PF00227.21 KPI35017.1 - 1e-55 187.9 0.1 1.3e-55 187.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KPI35017.1 - 1.2e-13 50.1 0.1 2.5e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribosomal_L1 PF00687.16 KPI35018.1 - 5.4e-22 78.2 0.0 7.8e-22 77.6 0.0 1.2 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family MRL1 PF13003.2 KPI35018.1 - 2.5 7.9 5.7 70 3.2 4.0 2.4 1 1 0 1 1 1 0 Ribosomal protein L1 TPR_12 PF13424.1 KPI35019.1 - 2.3e-21 75.4 13.6 3e-10 39.8 1.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 KPI35019.1 - 1.6e-10 40.1 1.0 0.061 12.9 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KPI35019.1 - 1.1e-09 37.7 6.0 0.00022 20.8 0.0 4.2 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 KPI35019.1 - 2.3e-09 36.4 13.1 0.0012 18.5 0.0 6.6 8 0 0 8 8 6 3 Tetratricopeptide repeat NB-ARC PF00931.17 KPI35019.1 - 4.8e-08 32.1 0.0 2.7e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.1 KPI35019.1 - 1.9e-06 27.5 17.0 0.018 14.9 0.9 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat AAA_16 PF13191.1 KPI35019.1 - 1.5e-05 25.0 1.3 0.00016 21.6 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain TPR_8 PF13181.1 KPI35019.1 - 0.00025 20.5 0.3 6.9 6.6 0.0 4.9 4 1 1 5 5 4 1 Tetratricopeptide repeat AAA_35 PF14516.1 KPI35019.1 - 0.0067 15.0 0.0 0.053 12.1 0.1 2.2 2 0 0 2 2 2 1 AAA-like domain TPR_14 PF13428.1 KPI35019.1 - 0.013 16.0 5.2 25 5.8 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 KPI35019.1 - 0.017 15.2 1.7 47 4.5 0.0 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KPI35019.1 - 0.081 13.4 0.4 12 6.6 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_22 PF13401.1 KPI35019.1 - 0.088 12.9 0.0 0.48 10.5 0.0 2.3 2 0 0 2 2 1 0 AAA domain TPR_7 PF13176.1 KPI35019.1 - 0.32 10.9 6.5 2.9 7.8 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat zf-Di19 PF05605.7 KPI35019.1 - 1.2 9.3 8.1 1.2 9.3 1.3 3.2 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KPI35019.1 - 7.1 7.2 16.7 3 8.3 0.1 5.0 4 1 0 4 4 4 0 C2H2-type zinc finger Peptidase_M1 PF01433.15 KPI35021.1 - 7.9e-104 347.8 0.0 1.1e-103 347.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KPI35021.1 - 3.5e-37 128.3 1.8 5.5e-37 127.7 1.3 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KPI35021.1 - 1.2e-16 60.9 1.6 2e-16 60.2 0.5 1.8 2 0 0 2 2 2 1 Peptidase MA superfamily PriCT_2 PF08707.6 KPI35021.1 - 0.58 10.0 6.7 0.15 11.9 0.6 3.0 5 0 0 5 5 5 0 Primase C terminal 2 (PriCT-2) PMT PF02366.13 KPI35022.1 - 4.2e-82 275.1 20.1 4.2e-82 275.1 13.9 2.5 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KPI35022.1 - 4.6e-38 130.6 0.2 6.5e-38 130.1 0.2 1.2 1 0 0 1 1 1 1 MIR domain Exo_endo_phos PF03372.18 KPI35023.1 - 3.6e-20 72.9 0.6 6.4e-20 72.1 0.4 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 KPI35023.1 - 0.0012 18.6 2.8 0.21 11.5 0.3 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 KPI35023.1 - 0.035 13.8 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 KPI35023.1 - 1.2 9.5 6.2 1.4 9.3 0.1 3.8 4 0 0 4 4 4 0 PQQ-like domain Nucleos_tra2_C PF07662.8 KPI35024.1 - 4.3e-70 235.4 2.2 1.1e-69 234.1 1.5 1.7 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KPI35024.1 - 4.2e-21 75.0 1.1 4.2e-21 75.0 0.7 2.8 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Lactonase PF10282.4 KPI35025.1 - 0.0095 15.0 0.1 0.26 10.3 0.0 2.6 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller TRI12 PF06609.8 KPI35026.1 - 1e-66 225.3 18.3 1.3e-66 225.0 12.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI35026.1 - 1.9e-24 86.0 57.0 7.4e-24 84.1 34.5 3.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI35026.1 - 2.1e-16 59.5 4.1 2.1e-16 59.5 2.8 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter EamA PF00892.15 KPI35026.1 - 0.037 14.0 0.2 0.037 14.0 0.2 4.8 5 1 0 5 5 5 0 EamA-like transporter family DUF2417 PF10329.4 KPI35026.1 - 0.083 12.2 0.1 0.083 12.2 0.1 2.2 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Methyltransf_23 PF13489.1 KPI35027.1 - 3.5e-12 46.3 0.0 8.1e-12 45.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI35027.1 - 0.025 15.0 0.0 0.062 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain zf-CHY PF05495.7 KPI35028.1 - 8.7e-16 57.8 16.1 1.2e-15 57.4 11.2 1.2 1 0 0 1 1 1 1 CHY zinc finger zf-RING_3 PF14369.1 KPI35028.1 - 0.0087 16.0 6.7 0.19 11.7 3.0 2.4 1 1 1 2 2 2 2 zinc-finger zf-FPG_IleRS PF06827.9 KPI35028.1 - 0.034 13.7 2.0 4.3 7.0 0.1 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF3195 PF11424.3 KPI35028.1 - 0.11 12.7 0.7 0.17 12.0 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3195) DNA_RNApol_7kD PF03604.8 KPI35028.1 - 0.12 11.8 1.9 3.7 7.1 0.0 3.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DUF3797 PF12677.2 KPI35028.1 - 0.26 10.9 0.1 0.26 10.9 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) Evr1_Alr PF04777.8 KPI35028.1 - 0.41 10.5 10.4 30 4.5 7.2 2.7 1 1 0 1 1 1 0 Erv1 / Alr family C1_4 PF07975.7 KPI35028.1 - 1.1 9.3 11.7 0.42 10.6 2.2 2.5 1 1 2 3 3 3 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.5 KPI35028.1 - 1.2 9.1 13.9 0.13 12.2 2.4 2.6 2 1 0 2 2 2 0 Zinc ribbon domain Cytochrom_c3_2 PF14537.1 KPI35028.1 - 1.4 9.3 9.2 6 7.2 6.4 1.9 1 1 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.1 KPI35028.1 - 1.8 8.2 10.6 4.2 7.0 7.4 1.7 1 1 0 1 1 1 0 Cytochrome c7 DZR PF12773.2 KPI35028.1 - 2.8 7.8 11.6 14 5.5 8.1 2.2 1 1 0 1 1 1 0 Double zinc ribbon DUF2296 PF10058.4 KPI35028.1 - 4.6 7.0 7.6 1.6 8.4 0.9 2.3 1 1 2 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) zf-C2H2_6 PF13912.1 KPI35028.1 - 5.3 7.0 10.1 0.61 10.0 0.7 3.2 3 1 1 4 4 4 0 C2H2-type zinc finger AA_permease PF00324.16 KPI35029.1 - 5.4e-135 450.4 37.6 6.2e-135 450.2 26.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI35029.1 - 5.1e-36 124.1 41.0 7.5e-36 123.5 28.4 1.2 1 0 0 1 1 1 1 Amino acid permease UPF0547 PF10571.4 KPI35030.1 - 0.023 14.3 4.0 3.8 7.3 0.4 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C3HC4_3 PF13920.1 KPI35030.1 - 0.049 13.3 1.9 4.9 6.8 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GFA PF04828.9 KPI35030.1 - 0.053 13.4 0.3 15 5.5 0.1 2.6 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF35_N PF12172.3 KPI35030.1 - 0.12 12.3 2.0 11 6.0 0.1 2.8 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.2 KPI35030.1 - 0.16 11.8 3.3 5 7.0 0.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon DNA_ligase_ZBD PF03119.11 KPI35030.1 - 0.35 10.6 9.7 3.5 7.4 0.3 3.5 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain zf-ribbon_3 PF13248.1 KPI35030.1 - 0.82 8.9 3.6 1.8 7.8 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KPI35030.1 - 1.7 8.6 4.5 22 5.0 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain FAD_binding_3 PF01494.14 KPI35031.1 - 1e-18 67.5 0.0 5.7e-13 48.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KPI35031.1 - 1.2e-06 28.4 0.2 2.7e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI35031.1 - 2.5e-06 26.6 1.0 8.6e-05 21.5 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI35031.1 - 7.1e-05 22.7 0.1 0.00023 21.1 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI35031.1 - 0.0054 15.6 0.2 0.008 15.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KPI35031.1 - 0.0065 14.9 0.3 0.01 14.3 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.16 KPI35031.1 - 0.0098 15.4 0.2 0.019 14.5 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Mur_ligase PF01225.20 KPI35031.1 - 0.027 14.5 0.5 2 8.5 0.1 2.5 2 0 0 2 2 2 0 Mur ligase family, catalytic domain Pyr_redox PF00070.22 KPI35031.1 - 0.03 14.7 3.9 0.051 13.9 0.1 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI35031.1 - 0.054 13.5 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KPI35031.1 - 0.065 12.8 0.1 0.28 10.8 0.0 2.1 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 KPI35031.1 - 0.068 11.9 0.0 0.095 11.5 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.9 KPI35031.1 - 0.08 11.5 0.1 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Fip1 PF05182.8 KPI35031.1 - 0.092 12.0 0.5 0.16 11.2 0.4 1.4 1 0 0 1 1 1 0 Fip1 motif GIDA PF01134.17 KPI35031.1 - 0.15 10.8 0.2 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Ank_2 PF12796.2 KPI35032.1 - 1.1e-85 282.0 2.4 1.9e-14 53.7 0.0 6.2 3 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KPI35032.1 - 3.4e-63 206.4 5.7 2.4e-06 27.0 0.0 13.2 13 0 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.1 KPI35032.1 - 1.1e-60 200.9 2.1 7.7e-13 48.5 0.0 10.5 2 2 9 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 KPI35032.1 - 3.8e-56 185.8 4.5 7.4e-09 35.5 0.0 8.3 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI35032.1 - 2.7e-45 147.8 0.3 0.00025 20.9 0.0 12.4 12 0 0 12 12 12 11 Ankyrin repeat Shigella_OspC PF06128.6 KPI35032.1 - 0.00011 21.7 0.0 23 4.3 0.0 6.3 3 2 4 8 8 8 0 Shigella flexneri OspC protein DUF4646 PF15496.1 KPI35032.1 - 0.037 14.0 0.2 0.42 10.6 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4646) Myosin_tail_1 PF01576.14 KPI35033.1 - 9.2e-06 23.6 40.5 9.2e-06 23.6 28.1 5.3 1 1 3 5 5 5 2 Myosin tail Filament PF00038.16 KPI35033.1 - 0.32 10.4 180.9 0.43 10.0 11.7 8.5 1 1 4 6 6 6 0 Intermediate filament protein IncA PF04156.9 KPI35033.1 - 1.5 8.4 203.7 0.55 9.7 22.0 10.3 1 1 8 9 9 9 0 IncA protein PfUIS3 PF11567.3 KPI35033.1 - 5.6 7.1 10.3 0.084 13.0 0.4 3.0 3 0 0 3 3 3 0 Plasmodium falciparum UIS3 membrane protein Aldedh PF00171.17 KPI35035.1 - 3.8e-14 51.9 1.5 3.5e-08 32.2 0.0 3.0 2 1 1 3 3 3 3 Aldehyde dehydrogenase family ThiF PF00899.16 KPI35036.1 - 2.9e-31 108.1 0.0 4.5e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KPI35036.1 - 0.001 19.1 0.0 0.05 13.7 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Peptidase_S15 PF02129.13 KPI35037.1 - 4.5e-41 141.0 0.0 7e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KPI35037.1 - 3.8e-34 118.4 0.1 5.6e-34 117.9 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KPI35037.1 - 2.1e-07 31.0 0.1 4.7e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI35037.1 - 0.00011 22.0 0.0 0.00039 20.1 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KPI35037.1 - 0.0016 18.2 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_GDSL_2 PF13472.1 KPI35038.1 - 7.6e-18 65.2 0.1 1.1e-17 64.6 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KPI35038.1 - 2.3e-15 57.0 0.0 3.1e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase p450 PF00067.17 KPI35039.1 - 2.3e-47 161.5 0.0 4.8e-40 137.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Thioredoxin PF00085.15 KPI35041.1 - 3.8e-64 212.8 5.8 9.2e-30 102.4 0.0 4.6 5 0 0 5 5 5 3 Thioredoxin Thioredoxin_6 PF13848.1 KPI35041.1 - 2.4e-55 187.1 0.8 5e-42 143.7 0.1 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.12 KPI35041.1 - 9.7e-13 47.6 0.7 2.3e-12 46.3 0.3 1.7 1 1 1 2 2 2 1 Calsequestrin Thioredoxin_8 PF13905.1 KPI35041.1 - 2.7e-11 43.4 0.0 0.00043 20.3 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KPI35041.1 - 1.6e-10 40.8 0.1 0.00041 20.3 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KPI35041.1 - 2.7e-09 37.1 6.5 0.00068 19.8 0.1 4.3 2 2 1 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 KPI35041.1 - 2.5e-06 27.1 5.5 0.0088 15.7 0.0 3.7 3 1 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 KPI35041.1 - 4.4e-05 23.0 6.4 0.018 14.6 0.0 3.8 4 0 0 4 4 4 2 Redoxin Thioredoxin_3 PF13192.1 KPI35041.1 - 0.018 14.8 0.2 0.21 11.4 0.1 2.7 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_4 PF13462.1 KPI35041.1 - 0.03 14.3 6.9 2.5 8.1 0.4 4.2 4 2 0 4 4 4 0 Thioredoxin CPSase_sm_chain PF00988.17 KPI35041.1 - 0.14 11.6 0.0 0.35 10.3 0.0 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain Sugar_tr PF00083.19 KPI35042.1 - 1.3e-113 379.9 26.1 1.5e-113 379.7 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI35042.1 - 1.9e-25 89.3 55.5 4.6e-24 84.7 18.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily FAA_hydrolase PF01557.13 KPI35043.1 - 7.3e-46 156.3 0.0 1e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KPI35043.1 - 4.9e-17 61.8 0.1 8e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal NOC3p PF07540.6 KPI35044.1 - 8.5e-28 96.4 0.0 8.5e-28 96.4 0.0 2.9 4 0 0 4 4 4 1 Nucleolar complex-associated protein CBF PF03914.12 KPI35044.1 - 4.2e-23 81.6 0.5 2.1e-22 79.3 0.0 2.2 2 0 0 2 2 2 1 CBF/Mak21 family Sua5_yciO_yrdC PF01300.13 KPI35045.1 - 3.3e-15 55.7 0.0 4.3e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination adh_short PF00106.20 KPI35046.1 - 1.7e-33 115.8 2.0 2.2e-33 115.5 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI35046.1 - 1.7e-30 106.5 0.2 2e-30 106.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI35046.1 - 1.7e-14 53.9 0.3 2.8e-14 53.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI35046.1 - 6.9e-05 22.3 0.4 0.0004 19.9 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DegV PF02645.11 KPI35046.1 - 0.031 13.3 0.0 0.068 12.2 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 Zn_clus PF00172.13 KPI35047.1 - 1.6e-05 24.7 11.6 2.8e-05 23.9 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KPI35048.1 - 1.4e-21 76.5 44.5 1.4e-21 76.5 30.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KPI35048.1 - 3.9e-17 61.6 25.8 3.8e-16 58.4 17.9 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cwf_Cwc_15 PF04889.7 KPI35052.1 - 4.5e-84 281.9 13.8 5.1e-84 281.8 9.6 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF2890 PF11081.3 KPI35052.1 - 0.028 14.4 12.2 0.042 13.9 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) SDA1 PF05285.7 KPI35052.1 - 0.046 12.9 15.9 0.051 12.8 11.0 1.2 1 0 0 1 1 1 0 SDA1 Adaptin_binding PF10199.4 KPI35052.1 - 0.12 12.6 11.5 0.2 11.9 7.9 1.4 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Nop14 PF04147.7 KPI35052.1 - 0.13 10.2 16.9 0.15 9.9 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 KPI35052.1 - 0.34 9.8 17.6 0.47 9.3 12.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF506 PF04720.7 KPI35052.1 - 0.85 9.2 4.1 1.2 8.7 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Presenilin PF01080.12 KPI35052.1 - 0.96 8.2 5.0 1.2 7.9 3.4 1.1 1 0 0 1 1 1 0 Presenilin SGT1 PF07093.6 KPI35052.1 - 1.3 7.3 13.1 1.6 7.0 9.1 1.1 1 0 0 1 1 1 0 SGT1 protein HNF-1_N PF04814.8 KPI35052.1 - 1.4 8.9 4.8 1.6 8.7 2.9 1.6 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus CDC45 PF02724.9 KPI35052.1 - 1.4 6.8 16.0 1.7 6.5 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 KPI35052.1 - 2.6 7.3 14.2 3.8 6.8 9.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) APG6 PF04111.7 KPI35052.1 - 4 6.3 8.8 5.5 5.9 6.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Pox_RNA_Pol_19 PF05320.7 KPI35052.1 - 6.7 6.4 9.5 10 5.8 6.6 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit AA_permease_2 PF13520.1 KPI35053.1 - 2.7e-40 138.2 58.7 3.3e-40 137.9 40.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI35053.1 - 1.8e-14 52.9 48.9 2.3e-14 52.6 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease AAA_12 PF13087.1 KPI35054.1 - 7.4e-37 126.6 0.0 1.2e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KPI35054.1 - 1.8e-26 93.1 0.1 3.2e-26 92.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KPI35054.1 - 8.1e-10 38.3 0.1 5.8e-09 35.5 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KPI35054.1 - 4.3e-07 29.7 0.2 0.00036 20.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain zf-CCCH PF00642.19 KPI35054.1 - 0.0001 21.9 5.5 0.0001 21.9 3.8 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_16 PF13191.1 KPI35054.1 - 0.00032 20.7 0.7 0.061 13.3 0.5 3.1 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 KPI35054.1 - 0.0017 17.4 0.1 0.031 13.2 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.1 KPI35054.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ResIII PF04851.10 KPI35054.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.24 KPI35054.1 - 0.16 11.4 1.0 0.41 10.1 0.0 2.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase zf-CCCH_2 PF14608.1 KPI35054.1 - 0.78 9.8 4.0 2.3 8.3 2.8 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Baculo_PEP_C PF04513.7 KPI35055.1 - 0.00041 20.1 10.8 0.092 12.5 0.1 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus SSFA2_C PF14723.1 KPI35055.1 - 0.0057 16.4 0.9 0.015 15.0 0.1 2.1 2 0 0 2 2 2 1 Sperm-specific antigen 2 C-terminus SlyX PF04102.7 KPI35055.1 - 0.023 15.0 3.0 1.6 9.1 0.0 3.1 2 0 0 2 2 2 0 SlyX Dynamitin PF04912.9 KPI35055.1 - 0.023 13.5 1.0 0.036 12.8 0.7 1.2 1 0 0 1 1 1 0 Dynamitin Fmp27_WPPW PF10359.4 KPI35055.1 - 0.023 13.1 0.4 0.056 11.8 0.0 1.7 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain NPV_P10 PF05531.7 KPI35055.1 - 0.061 13.5 3.0 0.22 11.8 0.2 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein WASH_WAHD PF11945.3 KPI35055.1 - 0.065 12.5 0.7 3.6 6.8 0.0 2.9 3 0 0 3 3 3 0 WAHD domain of WASH complex Gp58 PF07902.6 KPI35055.1 - 0.07 11.3 2.2 0.11 10.6 1.5 1.2 1 0 0 1 1 1 0 gp58-like protein EzrA PF06160.7 KPI35055.1 - 0.23 9.5 0.7 0.35 8.9 0.5 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF1664 PF07889.7 KPI35055.1 - 0.3 10.9 0.8 3.2 7.5 0.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 KPI35055.1 - 0.32 10.5 1.4 0.83 9.1 0.6 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 KPI35055.1 - 0.77 8.9 3.4 0.31 10.2 0.4 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.15 KPI35055.1 - 0.82 9.4 3.8 16 5.2 1.4 2.9 2 1 1 3 3 3 0 Prefoldin subunit SnoaL_2 PF12680.2 KPI35056.1 - 4.8e-07 30.1 0.8 6.6e-07 29.6 0.6 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 KPI35056.1 - 1.1e-06 28.1 0.1 1.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Med22 PF06179.7 KPI35058.1 - 0.061 13.3 0.1 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex zf-C2H2 PF00096.21 KPI35059.1 - 1.4e-08 34.6 25.9 0.04 14.2 0.7 6.5 5 1 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI35059.1 - 8.5e-08 32.0 25.6 0.052 13.9 0.1 6.0 4 1 1 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KPI35059.1 - 5.9e-06 25.9 13.9 1.4 8.9 0.0 5.8 5 1 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.2 KPI35059.1 - 0.026 14.7 13.9 10 6.4 0.3 5.9 5 1 0 5 5 5 0 Zinc-finger of C2H2 type zf-DHHC PF01529.15 KPI35060.1 - 2.1e-31 108.6 2.1 2.1e-31 108.6 1.4 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.2 KPI35060.1 - 4.8 7.0 10.4 9.7 6.1 7.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon DEAD PF00270.24 KPI35061.1 - 4.2e-11 42.6 0.0 1.2e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI35061.1 - 7.8e-11 41.6 0.1 2.8e-10 39.9 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KPI35061.1 - 0.022 13.5 0.0 0.036 12.8 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF2388 PF09498.5 KPI35061.1 - 0.052 13.1 0.2 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) Med21 PF11221.3 KPI35061.1 - 0.098 12.6 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Subunit 21 of Mediator complex ResIII PF04851.10 KPI35061.1 - 0.23 11.2 0.0 0.51 10.1 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PBP1_TM PF14812.1 KPI35061.1 - 1 9.6 5.1 0.41 10.9 0.6 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Melibiase PF02065.13 KPI35062.1 - 3.4e-116 388.2 0.0 4.6e-116 387.7 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 KPI35062.1 - 0.00082 18.3 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 HK PF02110.10 KPI35063.1 - 4.3e-80 268.4 1.0 4.8e-80 268.2 0.7 1.0 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.12 KPI35063.1 - 0.00011 21.6 0.1 0.00018 20.8 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KPI35063.1 - 0.00012 21.4 0.0 0.00017 20.8 0.0 1.3 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase MFS_1 PF07690.11 KPI35064.1 - 1e-13 50.7 53.4 2.1e-11 43.1 35.1 3.7 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF973 PF06157.6 KPI35064.1 - 1.7 7.5 19.9 5 6.0 9.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF973) Fungal_trans PF04082.13 KPI35065.1 - 3e-10 39.4 0.9 4.7e-10 38.7 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Melibiase PF02065.13 KPI35067.1 - 6.1e-15 54.8 0.0 7e-15 54.6 0.0 1.0 1 0 0 1 1 1 1 Melibiase UPF0113 PF03657.8 KPI35069.1 - 3.1e-06 26.9 0.0 4.1e-06 26.5 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 KPI35069.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 PUA domain MFS_1 PF07690.11 KPI35071.1 - 3.7e-27 94.9 31.0 4.2e-27 94.8 20.7 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI35071.1 - 1e-09 37.5 11.3 1.8e-09 36.7 7.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 KPI35071.1 - 0.031 14.0 0.1 0.031 14.0 0.1 2.3 2 0 0 2 2 2 0 MFS_1 like family LigB PF02900.13 KPI35072.1 - 6.2e-25 87.7 0.2 7.5e-25 87.4 0.1 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Peptidase_M14 PF00246.19 KPI35073.1 - 2e-17 63.6 0.0 2.7e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 KPI35073.1 - 0.0086 14.9 0.0 0.019 13.8 0.0 1.5 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family eIF-5_eIF-2B PF01873.12 KPI35074.1 - 3.8e-39 133.1 0.0 6.1e-39 132.5 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 KPI35074.1 - 3.7e-25 87.6 0.1 9.2e-25 86.4 0.1 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Cupin_2 PF07883.6 KPI35075.1 - 7.7e-08 31.7 0.0 1.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KPI35075.1 - 0.027 14.0 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_1 PF00190.17 KPI35075.1 - 0.049 13.0 0.0 0.091 12.1 0.0 1.5 1 1 0 1 1 1 0 Cupin Rhomboid PF01694.17 KPI35076.1 - 0.0051 16.8 9.0 0.54 10.2 3.2 3.2 2 1 0 2 2 2 2 Rhomboid family Voltage_CLC PF00654.15 KPI35077.1 - 2.6e-80 270.1 35.7 1.1e-52 179.2 7.8 2.6 2 1 1 3 3 3 2 Voltage gated chloride channel TAT_signal PF10518.4 KPI35077.1 - 0.033 14.1 1.2 0.033 14.1 0.8 2.8 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence TMP-TENI PF02581.12 KPI35078.1 - 2.8e-49 166.6 0.1 3.4e-49 166.3 0.1 1.0 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Methyltransf_3 PF01596.12 KPI35079.1 - 2.1e-31 108.5 0.0 2.5e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KPI35079.1 - 5.5e-14 52.8 0.0 1e-13 52.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI35079.1 - 2.6e-07 31.2 0.0 4.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI35079.1 - 0.00038 20.4 0.0 0.00052 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KPI35079.1 - 0.00052 19.5 0.0 0.00093 18.7 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KPI35079.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 KPI35079.1 - 0.018 14.3 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase ABC2_membrane PF01061.19 KPI35080.1 - 1e-67 227.3 63.8 1.1e-41 142.3 20.7 4.0 4 1 1 5 5 4 3 ABC-2 type transporter PDR_CDR PF06422.7 KPI35080.1 - 2.6e-35 120.1 6.5 2.7e-31 107.2 0.0 3.5 4 0 0 4 4 3 2 CDR ABC transporter ABC_tran PF00005.22 KPI35080.1 - 7.7e-33 113.6 0.0 2.1e-16 60.4 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_trans_N PF14510.1 KPI35080.1 - 4.6e-15 55.4 0.0 1.1e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 KPI35080.1 - 3.8e-09 36.5 0.1 1.2e-05 25.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KPI35080.1 - 2.6e-08 34.0 0.5 7.6e-06 26.0 0.2 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KPI35080.1 - 4.6e-07 29.4 0.0 0.0011 18.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KPI35080.1 - 1.1e-05 26.2 0.0 0.0056 17.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KPI35080.1 - 7.1e-05 22.0 0.1 0.0018 17.5 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KPI35080.1 - 8.5e-05 22.8 0.1 0.004 17.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 KPI35080.1 - 0.00014 21.0 29.5 0.014 14.4 0.5 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.1 KPI35080.1 - 0.00021 20.7 1.1 0.02 14.3 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KPI35080.1 - 0.00066 19.8 0.1 0.26 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KPI35080.1 - 0.00075 18.9 0.6 0.0067 15.8 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 KPI35080.1 - 0.001 18.7 0.1 0.17 11.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 KPI35080.1 - 0.0055 16.4 0.1 2.9 7.7 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 KPI35080.1 - 0.016 15.4 0.2 5.9 7.1 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KPI35080.1 - 0.028 14.3 0.2 0.67 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KPI35080.1 - 0.033 13.8 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 KPI35080.1 - 0.049 13.2 0.3 5.9 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KPI35080.1 - 0.15 11.9 0.0 9 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 KPI35080.1 - 0.16 11.9 0.0 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KPI35080.1 - 0.16 11.1 0.0 12 5.0 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 KPI35080.1 - 1.9 8.1 5.7 1.2 8.7 0.1 2.9 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 Fis1_TPR_C PF14853.1 KPI35082.1 - 0.0045 16.8 0.2 0.0083 15.9 0.1 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat FlxA PF14282.1 KPI35082.1 - 0.011 15.6 0.1 0.027 14.4 0.1 1.8 1 0 0 1 1 1 0 FlxA-like protein TUDOR PF00567.19 KPI35082.1 - 0.032 14.0 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Tudor domain DUF3534 PF12053.3 KPI35082.1 - 0.034 14.0 1.1 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3534) DUF4537 PF15057.1 KPI35082.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) PRCC PF10253.4 KPI35082.1 - 0.17 12.6 3.6 0.98 10.0 0.4 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting MFS_1 PF07690.11 KPI35084.1 - 1.1e-32 113.2 41.3 1.1e-32 113.2 28.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Isochorismatase PF00857.15 KPI35085.1 - 1.2e-22 80.6 0.1 1.4e-22 80.4 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family Terminase_1 PF03354.10 KPI35085.1 - 0.022 13.2 0.1 0.029 12.8 0.0 1.1 1 0 0 1 1 1 0 Phage Terminase NmrA PF05368.8 KPI35086.1 - 6.8e-26 90.9 0.0 1.3e-25 90.0 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI35086.1 - 1.4e-16 61.0 0.1 1.8e-16 60.6 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI35086.1 - 4.8e-06 26.1 0.0 6.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KPI35086.1 - 4.6e-05 22.4 0.1 0.059 12.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 KPI35086.1 - 0.003 17.5 1.0 0.0066 16.3 0.2 2.0 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KPI35086.1 - 0.013 14.4 0.1 1.8 7.3 0.0 2.4 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.5 KPI35086.1 - 0.031 13.9 0.3 0.064 12.9 0.0 1.8 2 0 0 2 2 2 0 KR domain DUF2002 PF09400.5 KPI35086.1 - 0.11 12.2 0.0 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2002) Anp1 PF03452.9 KPI35087.1 - 4.9e-101 337.4 0.0 8.2e-101 336.6 0.0 1.3 1 0 0 1 1 1 1 Anp1 Glyco_tranf_2_4 PF13704.1 KPI35087.1 - 0.019 15.2 0.7 0.092 13.0 0.1 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 Rad54_N PF08658.5 KPI35087.1 - 0.057 13.1 1.0 0.13 12.0 0.7 1.5 1 0 0 1 1 1 0 Rad54 N terminal Thioredoxin PF00085.15 KPI35088.1 - 2.8e-29 100.8 0.1 3.4e-29 100.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KPI35088.1 - 9.6e-07 28.9 0.2 6.3e-06 26.3 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KPI35088.1 - 1.2e-05 25.3 0.1 0.00044 20.3 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 KPI35088.1 - 0.00042 20.0 0.1 0.00057 19.5 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 KPI35088.1 - 0.035 14.1 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.1 KPI35088.1 - 0.062 12.8 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Fer4_15 PF13459.1 KPI35088.1 - 0.12 12.9 0.4 0.45 11.1 0.3 1.8 1 1 0 1 1 1 0 4Fe-4S single cluster domain ADH_N PF08240.7 KPI35089.1 - 1.3e-08 34.5 0.0 2.3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI35089.1 - 6.7e-05 22.4 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI35089.1 - 0.0012 19.7 0.0 0.0038 18.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Cupin_2 PF07883.6 KPI35091.1 - 2.4e-05 23.7 0.9 2.4e-05 23.7 0.7 2.1 2 1 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 KPI35091.1 - 0.009 15.4 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Cupin CDO_I PF05995.7 KPI35091.1 - 0.071 12.2 0.1 0.08 12.1 0.1 1.2 1 0 0 1 1 1 0 Cysteine dioxygenase type I Adaptin_N PF01602.15 KPI35092.1 - 3.1e-104 349.2 0.2 3.5e-104 348.9 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KPI35092.1 - 1.1e-08 35.1 4.9 2.6e-05 24.3 0.0 4.9 5 1 0 6 6 6 2 HEAT repeats HEAT PF02985.17 KPI35092.1 - 1.5e-07 30.8 0.2 0.12 12.5 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat Cohesin_HEAT PF12765.2 KPI35092.1 - 0.00041 20.2 0.6 0.63 10.0 0.0 3.4 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion CRISPR_Cse2 PF09485.5 KPI35092.1 - 0.016 15.2 0.1 0.051 13.6 0.0 1.8 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) TruB_C PF09142.6 KPI35092.1 - 0.024 14.2 0.3 0.064 12.9 0.2 1.7 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal SPO22 PF08631.5 KPI35092.1 - 0.075 12.1 0.2 0.37 9.8 0.1 2.2 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like Cnd1 PF12717.2 KPI35092.1 - 0.083 12.7 0.1 2.9 7.7 0.0 3.0 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KPI35092.1 - 0.36 11.3 12.7 1.8 9.1 0.0 5.9 7 1 1 8 8 8 0 HEAT-like repeat RNA_pol_3_Rpc31 PF11705.3 KPI35092.1 - 1.4 8.8 14.1 2.6 7.9 9.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1237 PF06824.6 KPI35093.1 - 8.5e-91 304.6 0.0 1e-90 304.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) HORMA PF02301.13 KPI35094.1 - 7.9e-22 77.7 0.0 1.1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 HORMA domain ChitinaseA_N PF08329.5 KPI35095.1 - 0.052 13.3 0.1 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 Chitinase A, N-terminal domain JAB PF01398.16 KPI35096.1 - 2.1e-24 85.4 0.0 4.9e-24 84.2 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KPI35096.1 - 5.1e-05 22.7 0.0 0.00018 20.9 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain MAP65_ASE1 PF03999.7 KPI35097.1 - 4.7e-76 256.7 3.6 4.7e-76 256.7 2.5 2.9 2 1 0 3 3 3 1 Microtubule associated protein (MAP65/ASE1 family) Baculo_PEP_C PF04513.7 KPI35097.1 - 0.0011 18.8 0.6 0.0046 16.7 0.2 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.16 KPI35097.1 - 0.0045 17.2 3.9 0.087 13.1 0.6 3.3 2 0 0 2 2 2 1 Spectrin repeat Fungal_trans PF04082.13 KPI35098.1 - 3e-13 49.2 0.4 5.4e-13 48.4 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2859 PF11072.3 KPI35098.1 - 0.037 13.4 0.2 0.088 12.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) UpxZ PF06603.6 KPI35098.1 - 0.11 12.5 0.3 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists DAO PF01266.19 KPI35099.1 - 2.3e-36 125.4 0.0 3e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KPI35099.1 - 0.0023 18.0 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI35099.1 - 0.0024 17.8 0.0 0.0065 16.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 KPI35099.1 - 0.049 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 ThiF family Pyr_redox_2 PF07992.9 KPI35099.1 - 0.052 13.4 0.0 1.8 8.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KPI35099.1 - 0.079 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KPI35099.1 - 0.091 13.1 0.0 0.28 11.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KPI35099.1 - 0.1 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain adh_short PF00106.20 KPI35099.1 - 0.1 12.5 0.1 0.91 9.4 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase FAD_binding_2 PF00890.19 KPI35099.1 - 0.13 11.0 0.2 0.19 10.5 0.1 1.4 1 1 0 1 1 1 0 FAD binding domain ADH_zinc_N_2 PF13602.1 KPI35100.1 - 1.9e-22 80.4 0.0 4.7e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans_2 PF11951.3 KPI35100.1 - 4.4e-09 35.4 2.2 7.7e-09 34.6 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.7 KPI35100.1 - 0.012 15.3 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain DUF829 PF05705.9 KPI35101.1 - 9.4e-41 140.0 0.1 1.1e-40 139.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 KPI35101.1 - 0.00011 22.1 0.1 0.00014 21.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4407 PF14362.1 KPI35102.1 - 0.16 10.9 9.5 1.1 8.1 2.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ACC_epsilon PF13822.1 KPI35102.1 - 1.7 9.0 0.0 1.7 9.0 0.0 3.4 5 0 0 5 5 5 0 Acyl-CoA carboxylase epsilon subunit DUF1993 PF09351.5 KPI35102.1 - 3.5 7.5 8.0 5.6 6.8 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Aldedh PF00171.17 KPI35103.1 - 1.6e-33 115.7 0.0 2e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Vinculin PF01044.14 KPI35103.1 - 0.1 10.5 0.1 0.12 10.3 0.1 1.1 1 0 0 1 1 1 0 Vinculin family ThiF PF00899.16 KPI35104.1 - 6.5e-37 126.3 0.3 1.2e-36 125.5 0.2 1.4 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.1 KPI35104.1 - 0.0083 16.3 0.3 0.029 14.6 0.2 1.9 1 1 0 1 1 1 1 Putative NAD(P)-binding Saccharop_dh PF03435.13 KPI35104.1 - 0.017 14.1 1.0 0.17 10.8 0.3 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase TrkA_N PF02254.13 KPI35104.1 - 0.019 14.9 0.7 0.072 13.0 0.1 2.3 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 KPI35104.1 - 0.031 13.6 0.1 0.06 12.7 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 KPI35104.1 - 0.075 13.1 0.2 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_17 PF00332.13 KPI35104.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 AlaDh_PNT_C PF01262.16 KPI35104.1 - 0.12 11.8 0.5 0.25 10.8 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 KPI35104.1 - 0.13 11.7 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pro_dh PF01619.13 KPI35105.1 - 7.7e-32 110.5 0.0 1.1e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase CRIC_ras_sig PF10534.4 KPI35106.1 - 0.029 14.4 0.1 1.1 9.3 0.0 2.8 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras IBN_N PF03810.14 KPI35107.1 - 2.1e-06 27.5 0.0 3e-05 23.8 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.17 KPI35107.1 - 0.0012 18.7 1.5 5.7 7.3 0.0 5.4 4 0 0 4 4 4 1 HEAT repeat Xpo1 PF08389.7 KPI35107.1 - 0.012 15.5 0.1 0.99 9.3 0.0 4.0 4 1 0 4 4 4 0 Exportin 1-like protein CAS_CSE1 PF03378.10 KPI35107.1 - 0.012 13.9 0.0 0.024 12.9 0.0 1.4 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Ribonuc_red_sm PF00268.16 KPI35108.1 - 4.9e-120 399.7 0.8 5.9e-120 399.5 0.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Acetyltransf_10 PF13673.1 KPI35109.1 - 0.00032 20.8 0.0 0.00072 19.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KPI35109.1 - 0.00086 19.2 0.0 0.0032 17.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FA_desaturase PF00487.19 KPI35110.1 - 1.4e-41 142.6 26.7 2e-41 142.1 18.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase COPI_assoc PF08507.5 KPI35111.1 - 2.2e-33 114.8 4.0 2.4e-33 114.7 2.8 1.0 1 0 0 1 1 1 1 COPI associated protein DUF4386 PF14329.1 KPI35111.1 - 2.7 7.4 12.4 0.05 13.0 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) DUF1212 PF06738.7 KPI35111.1 - 4.6 6.6 7.5 5.7 6.3 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Mannosyl_trans3 PF11051.3 KPI35112.1 - 1.4e-70 237.7 0.0 2.8e-70 236.7 0.0 1.5 1 1 0 1 1 1 1 Mannosyltransferase putative Aldedh PF00171.17 KPI35114.1 - 4.5e-40 137.3 0.0 5e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short PF00106.20 KPI35115.1 - 2.1e-11 44.0 0.1 2.3e-10 40.6 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI35115.1 - 1.6e-05 24.7 0.0 3.5e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KPI35115.1 - 0.032 13.6 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.16 KPI35115.1 - 0.11 12.3 0.2 0.3 10.9 0.2 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KPI35115.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4211 PF13926.1 KPI35117.1 - 6.4e-33 113.3 0.0 2.3e-32 111.5 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) CDC27 PF09507.5 KPI35118.1 - 1.2e-70 238.9 46.8 1.4e-70 238.7 32.4 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Prefoldin PF02996.12 KPI35121.1 - 8.2e-23 80.3 0.0 1e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KPI35121.1 - 0.0024 17.6 0.4 0.13 12.0 0.0 2.1 2 0 0 2 2 2 1 Prefoldin subunit Fib_alpha PF08702.5 KPI35121.1 - 0.0082 16.2 2.2 0.12 12.4 0.2 2.1 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family Dynamitin PF04912.9 KPI35121.1 - 0.024 13.4 1.1 0.17 10.6 0.1 1.9 2 0 0 2 2 2 0 Dynamitin Serine_rich PF08824.5 KPI35121.1 - 0.073 12.7 0.4 0.74 9.5 0.1 2.0 2 0 0 2 2 2 0 Serine rich protein interaction domain IncA PF04156.9 KPI35121.1 - 0.073 12.6 2.9 0.39 10.2 0.2 2.0 2 0 0 2 2 2 0 IncA protein UPF0449 PF15136.1 KPI35121.1 - 0.077 13.2 0.7 0.61 10.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 COG5 PF10392.4 KPI35121.1 - 0.077 12.9 0.9 0.57 10.1 0.1 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 SYCE1 PF15233.1 KPI35121.1 - 0.16 11.8 1.4 1.4 8.8 0.1 2.0 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 COG2 PF06148.6 KPI35121.1 - 0.2 11.5 1.2 8 6.3 0.3 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mst1_SARAH PF11629.3 KPI35121.1 - 0.23 11.2 1.1 0.38 10.6 0.2 1.7 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 TMF_DNA_bd PF12329.3 KPI35121.1 - 1.1 9.1 4.1 4.4 7.1 0.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IF-2B PF01008.12 KPI35122.1 - 1.6e-26 92.9 0.0 2.8e-26 92.1 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family Lipocalin_5 PF13924.1 KPI35123.1 - 1.5e-14 53.8 0.0 2.8e-12 46.5 0.0 2.8 1 1 0 1 1 1 1 Lipocalin-like domain Epimerase PF01370.16 KPI35124.1 - 4.6e-10 39.3 0.0 6.6e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI35124.1 - 6.5e-05 23.0 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KPI35124.1 - 0.00028 21.1 0.0 0.0006 20.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain PGAMP PF07644.6 KPI35124.1 - 0.016 14.8 0.3 2 8.2 0.1 2.4 2 0 0 2 2 2 0 Planctomycete PGAMP adh_short PF00106.20 KPI35124.1 - 0.022 14.7 0.0 0.086 12.7 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_4 PF07993.7 KPI35124.1 - 0.079 11.8 0.0 3.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein Saccharop_dh PF03435.13 KPI35124.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Acetyltransf_9 PF13527.1 KPI35125.1 - 4.5e-08 32.9 0.1 1.2e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KPI35125.1 - 6.4e-07 29.4 0.0 9.6e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KPI35125.1 - 0.0087 16.0 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KPI35125.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein DnaJ PF00226.26 KPI35126.1 - 8.3e-19 67.0 1.0 8.3e-19 67.0 0.7 2.0 2 0 0 2 2 2 1 DnaJ domain DUF1590 PF07629.6 KPI35126.1 - 0.048 13.2 0.6 0.16 11.6 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) RRM_1 PF00076.17 KPI35126.1 - 0.13 11.9 0.3 8 6.1 0.4 3.0 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI35126.1 - 0.19 11.6 0.7 0.67 9.8 0.5 1.9 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cwf_Cwc_15 PF04889.7 KPI35126.1 - 0.21 11.2 16.5 0.31 10.6 11.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein tRNA-synt_2b PF00587.20 KPI35127.1 - 1.1e-29 103.2 0.0 1.7e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) zf-RING_3 PF14369.1 KPI35127.1 - 0.099 12.6 1.1 8 6.5 0.0 2.5 2 0 0 2 2 2 0 zinc-finger RRM_1 PF00076.17 KPI35128.1 - 4.5e-81 266.4 8.2 2.6e-21 75.0 0.3 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI35128.1 - 3.3e-55 183.9 1.9 8.5e-15 54.5 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI35128.1 - 4e-42 141.8 0.3 7.2e-09 35.3 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KPI35128.1 - 3.1e-30 103.6 0.3 1.3e-29 101.6 0.2 2.1 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 KPI35128.1 - 0.00015 21.4 4.1 0.35 10.6 0.1 3.8 3 0 0 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.1 KPI35128.1 - 0.00044 19.9 0.1 11 5.8 0.0 4.5 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif TC1 PF15063.1 KPI35128.1 - 0.0019 17.6 0.2 3.6 7.1 0.0 3.0 3 0 0 3 3 3 2 Thyroid cancer protein 1 OB_RNB PF08206.6 KPI35128.1 - 0.013 14.9 0.3 7.4 6.1 0.0 3.8 3 0 0 3 3 3 0 Ribonuclease B OB domain CbiG_mid PF11761.3 KPI35128.1 - 0.1 12.8 0.0 17 5.6 0.0 2.9 2 0 0 2 2 2 0 Cobalamin biosynthesis central region DUF2672 PF10878.3 KPI35128.1 - 0.21 11.3 2.2 0.26 11.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2672) Aminotran_3 PF00202.16 KPI35129.1 - 4.6e-99 331.4 0.1 5.9e-99 331.1 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF3301 PF11743.3 KPI35129.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) IBR PF01485.16 KPI35130.1 - 2.6e-07 30.3 30.0 3.1e-05 23.7 4.5 3.5 3 0 0 3 3 3 2 IBR domain Fungal_trans_2 PF11951.3 KPI35132.1 - 1.2e-09 37.2 0.0 2.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GATA PF00320.22 KPI35133.1 - 5.7e-32 108.7 19.2 2e-16 59.0 2.6 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KPI35133.1 - 3.9e-06 26.0 7.4 0.0027 16.9 0.7 3.2 2 1 1 3 3 3 3 TFIIB zinc-binding zf-ribbon_3 PF13248.1 KPI35133.1 - 0.00052 19.1 7.7 0.032 13.4 0.2 2.8 2 1 0 2 2 2 2 zinc-ribbon domain RRN7 PF11781.3 KPI35133.1 - 0.00071 19.0 6.2 0.0034 16.8 0.3 2.6 2 1 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 KPI35133.1 - 0.0046 16.8 1.6 2 8.4 0.1 2.6 2 0 0 2 2 2 2 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 KPI35133.1 - 0.0053 16.3 3.5 0.28 10.8 0.1 2.6 2 0 0 2 2 2 2 Putative transposase DNA-binding domain ArfGap PF01412.13 KPI35133.1 - 0.0084 15.8 2.4 0.24 11.2 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf eIF-5_eIF-2B PF01873.12 KPI35133.1 - 0.12 12.0 4.1 2.9 7.5 0.1 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-Sec23_Sec24 PF04810.10 KPI35133.1 - 0.25 10.9 7.6 0.33 10.5 0.2 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DZR PF12773.2 KPI35133.1 - 0.37 10.6 15.4 1.6 8.5 0.6 3.4 2 2 1 3 3 3 0 Double zinc ribbon Auto_anti-p27 PF06677.7 KPI35133.1 - 3.4 7.5 7.0 11 5.9 0.6 2.9 2 2 1 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-FCS PF06467.9 KPI35133.1 - 6.4 6.5 8.7 13 5.5 0.0 3.7 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif DUF3722 PF12519.3 KPI35135.1 - 6.3e-75 251.7 3.1 1e-74 251.0 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Mei4 PF13971.1 KPI35136.1 - 0.015 14.2 0.0 0.033 13.1 0.0 1.5 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 CBF PF03914.12 KPI35137.1 - 2.4e-40 137.6 0.3 9.7e-40 135.7 0.1 2.1 2 0 0 2 2 2 1 CBF/Mak21 family HYLS1_C PF15311.1 KPI35137.1 - 0.027 14.6 0.2 0.077 13.2 0.2 1.7 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus DUF3507 PF12015.3 KPI35137.1 - 0.045 13.2 0.1 0.12 11.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) Tom22 PF04281.8 KPI35138.1 - 3.4e-42 143.2 0.5 3.9e-42 143.0 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 YL1 PF05764.8 KPI35138.1 - 0.028 14.0 3.7 0.04 13.5 2.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Pan_kinase PF03309.9 KPI35138.1 - 0.12 11.9 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Type III pantothenate kinase OTU PF02338.14 KPI35139.1 - 2.4e-11 44.2 0.0 5.5e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease DUF2036 PF09724.4 KPI35142.1 - 1.7e-07 30.6 0.0 1.7e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2036) DUF721 PF05258.7 KPI35142.1 - 0.11 12.6 0.1 0.51 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF721) TIM PF00121.13 KPI35144.1 - 7.2e-86 287.2 0.0 1.1e-85 286.6 0.0 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase Anp1 PF03452.9 KPI35144.1 - 2.7e-17 62.8 0.0 2e-13 50.1 0.0 2.3 2 0 0 2 2 2 2 Anp1 Aa_trans PF01490.13 KPI35145.1 - 1.5e-25 89.5 31.2 2.9e-25 88.6 21.6 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Collagen PF01391.13 KPI35145.1 - 0.67 9.5 3.6 1.3 8.6 2.5 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) MFS_1 PF07690.11 KPI35146.1 - 5.2e-25 87.9 31.4 8e-25 87.2 21.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4449 PF14613.1 KPI35148.1 - 1.1e-65 220.6 5.0 1.1e-65 220.6 3.4 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Prp18 PF02840.10 KPI35148.1 - 0.12 12.2 0.1 0.12 12.2 0.0 3.2 3 1 1 4 4 4 0 Prp18 domain DUF1237 PF06824.6 KPI35149.1 - 1.7e-49 168.6 0.0 1.9e-49 168.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) DUF3594 PF12165.3 KPI35149.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3594) MFS_1 PF07690.11 KPI35151.1 - 1.3e-35 122.7 25.7 1.9e-35 122.1 17.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily P5CR_dimer PF14748.1 KPI35153.1 - 5.6e-26 90.6 2.4 1.1e-25 89.7 0.8 2.2 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KPI35153.1 - 3.2e-10 40.2 0.3 3e-09 37.1 0.1 2.5 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.12 KPI35153.1 - 0.00031 19.6 0.0 0.00051 19.0 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase Nuf2 PF03800.9 KPI35154.1 - 3.6e-43 147.0 1.3 8.4e-43 145.8 0.1 2.2 2 0 0 2 2 2 1 Nuf2 family DUF3584 PF12128.3 KPI35154.1 - 0.0021 15.4 40.8 0.0031 14.9 28.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Syntaxin-6_N PF09177.6 KPI35154.1 - 0.0023 18.3 0.8 0.0023 18.3 0.5 4.7 1 1 3 4 4 4 1 Syntaxin 6, N-terminal DUF812 PF05667.6 KPI35154.1 - 0.0049 15.4 33.6 0.0094 14.5 23.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Reo_sigmaC PF04582.7 KPI35154.1 - 0.0066 15.6 8.4 0.35 10.0 0.6 3.0 1 1 2 3 3 3 3 Reovirus sigma C capsid protein DASH_Hsk3 PF08227.6 KPI35154.1 - 0.0083 16.2 5.2 0.23 11.6 0.5 3.3 3 0 0 3 3 3 1 DASH complex subunit Hsk3 like CENP-F_leu_zip PF10473.4 KPI35154.1 - 5.9 6.7 59.8 0.87 9.4 12.7 3.7 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.4 KPI35154.1 - 6 7.0 40.2 1.2 9.2 2.8 5.1 2 2 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCPsignal PF00015.16 KPI35154.1 - 9.7 5.6 19.8 3 7.3 3.2 3.3 1 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain GCV_T PF01571.16 KPI35155.1 - 1e-08 34.8 0.0 5.4e-08 32.4 0.0 2.2 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KPI35155.1 - 0.0058 16.6 0.0 0.026 14.5 0.0 2.2 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF1989 PF09347.5 KPI35155.1 - 0.03 13.7 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) R3H PF01424.17 KPI35156.1 - 7.7e-09 35.1 0.9 1.4e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 R3H domain G-patch PF01585.18 KPI35156.1 - 5.1e-08 32.5 1.6 1.2e-07 31.4 1.1 1.7 1 0 0 1 1 1 1 G-patch domain Chromo PF00385.19 KPI35156.1 - 0.0011 18.5 0.0 0.0037 16.9 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain G-patch_2 PF12656.2 KPI35156.1 - 0.093 12.5 6.1 0.069 13.0 0.7 3.6 2 1 0 2 2 2 0 DExH-box splicing factor binding site DUF1993 PF09351.5 KPI35157.1 - 1.4e-30 106.3 0.0 1.6e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DinB_2 PF12867.2 KPI35157.1 - 0.011 16.1 0.1 0.016 15.5 0.1 1.2 1 0 0 1 1 1 0 DinB superfamily ketoacyl-synt PF00109.21 KPI35158.1 - 4.1e-61 206.6 0.1 7.6e-61 205.7 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KPI35158.1 - 6.5e-58 196.5 0.1 1.2e-57 195.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KPI35158.1 - 2.2e-55 187.9 0.1 3.6e-55 187.2 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KPI35158.1 - 1.6e-53 181.0 0.3 2.9e-52 176.9 0.1 2.8 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KPI35158.1 - 5.3e-41 140.3 1.9 1.4e-39 135.7 0.1 3.3 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KPI35158.1 - 2.4e-35 120.9 0.3 5.4e-35 119.8 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KPI35158.1 - 2.5e-17 62.6 0.0 1e-16 60.6 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KPI35158.1 - 2.1e-15 57.0 0.0 5.8e-15 55.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI35158.1 - 5e-09 35.9 0.0 1.1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KPI35158.1 - 3.3e-08 34.4 0.0 1.6e-07 32.2 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KPI35158.1 - 6.6e-08 32.4 0.0 1.8e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KPI35158.1 - 2.9e-07 30.2 0.2 7.2e-07 28.9 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 KPI35158.1 - 1.9e-06 28.4 0.1 1.9e-05 25.1 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI35158.1 - 2.9e-06 27.6 0.0 9.6e-06 26.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KPI35158.1 - 0.00034 20.8 0.1 0.0016 18.6 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site DUF938 PF06080.7 KPI35158.1 - 0.0081 15.7 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_28 PF02636.12 KPI35158.1 - 0.052 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.4 KPI35158.1 - 0.29 10.5 0.0 0.72 9.2 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Acyl_transf_3 PF01757.17 KPI35159.1 - 6.5e-22 77.8 22.4 8.1e-20 70.9 15.5 2.1 1 1 0 1 1 1 1 Acyltransferase family ABC_tran_2 PF12848.2 KPI35160.1 - 0.088 12.6 3.6 3.7 7.4 0.4 2.5 2 0 0 2 2 2 0 ABC transporter UPF0203 PF05254.7 KPI35160.1 - 0.099 12.5 0.0 20 5.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) ECH PF00378.15 KPI35161.1 - 1.1e-31 109.8 0.1 2e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family zf-TFIIB PF13453.1 KPI35162.1 - 0.007 15.5 2.4 0.061 12.5 1.6 2.2 1 1 0 1 1 1 1 Transcription factor zinc-finger MRG PF05712.8 KPI35162.1 - 0.057 12.3 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 MRG Shikimate_dh_N PF08501.6 KPI35163.1 - 1.4e-20 73.1 0.0 3.3e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KPI35163.1 - 4.8e-15 55.8 0.0 7.1e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 KPI35163.1 - 0.037 13.0 0.0 0.055 12.4 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Beta-lactamase PF00144.19 KPI35164.1 - 5.9e-39 134.0 0.0 8.9e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase HATPase_c_3 PF13589.1 KPI35165.1 - 5.8e-05 22.7 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KPI35165.1 - 9.7e-05 22.0 0.0 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YkyA PF10368.4 KPI35165.1 - 2.5 7.3 2.8 1.1 8.6 0.2 1.5 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein 2-oxoacid_dh PF00198.18 KPI35166.1 - 1.6e-79 266.4 0.1 2.2e-79 266.0 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KPI35166.1 - 4.3e-20 71.1 2.5 8.1e-20 70.2 1.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KPI35166.1 - 2.1e-05 24.0 0.7 0.00041 19.9 0.1 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 KPI35166.1 - 3.9e-05 22.9 3.4 0.0003 20.0 0.5 2.4 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 KPI35166.1 - 0.0014 18.9 0.5 0.09 13.1 0.1 2.4 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.1 KPI35166.1 - 0.0021 17.7 1.7 0.58 9.9 0.0 2.9 2 1 1 3 3 3 2 RnfC Barrel sandwich hybrid domain HlyD PF00529.15 KPI35166.1 - 0.0023 17.2 0.1 0.0046 16.3 0.1 1.5 1 0 0 1 1 1 1 HlyD family secretion protein GCV_H PF01597.14 KPI35166.1 - 0.02 14.5 0.2 0.041 13.5 0.2 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF3614 PF12267.3 KPI35166.1 - 0.048 13.9 0.1 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) PRCC PF10253.4 KPI35166.1 - 0.12 13.0 9.1 0.23 12.1 6.3 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Mitofilin PF09731.4 KPI35166.1 - 3.2 6.2 9.3 4.2 5.8 6.5 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DAO PF01266.19 KPI35167.1 - 4.7e-44 150.7 0.0 7e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI35167.1 - 3.9e-07 30.1 0.0 0.01 15.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI35167.1 - 8e-07 29.3 0.0 0.0021 18.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI35167.1 - 3.7e-06 26.0 0.3 0.00041 19.3 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 KPI35167.1 - 4.2e-06 26.6 0.1 9.8e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KPI35167.1 - 8.2e-05 21.8 0.0 0.0018 17.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 KPI35167.1 - 0.00039 20.2 0.0 0.067 12.9 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KPI35167.1 - 0.00039 19.0 0.0 0.15 10.4 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein ThiF PF00899.16 KPI35167.1 - 0.0013 18.5 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 ThiF family Pyr_redox PF00070.22 KPI35167.1 - 0.022 15.1 0.0 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PSI_PsaE PF02427.12 KPI35167.1 - 0.053 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IV / PsaE GIDA PF01134.17 KPI35167.1 - 0.08 11.7 0.0 8.2 5.1 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 KPI35167.1 - 0.09 11.8 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GMC_oxred_N PF00732.14 KPI35167.1 - 0.095 11.8 0.0 4.5 6.3 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase ApbA PF02558.11 KPI35167.1 - 0.12 11.8 0.1 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MBOAT_2 PF13813.1 KPI35168.1 - 1.9e-13 50.3 7.9 9.4e-13 48.0 5.5 2.3 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Bys1 PF04681.7 KPI35169.1 - 0.003 17.2 0.2 0.0061 16.2 0.1 1.5 1 1 0 1 1 1 1 Blastomyces yeast-phase-specific protein Thaumatin PF00314.12 KPI35169.1 - 0.0044 16.5 2.5 0.056 12.8 0.1 2.8 1 1 2 3 3 3 1 Thaumatin family Iso_dh PF00180.15 KPI35170.1 - 4.5e-107 358.0 0.0 5.1e-107 357.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AMP-binding PF00501.23 KPI35171.1 - 3.2e-83 279.4 0.0 4.1e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI35171.1 - 3.6e-13 50.2 0.2 9.1e-13 48.9 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MUG113 PF13455.1 KPI35172.1 - 9.4e-21 74.0 0.1 2.1e-20 72.9 0.1 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KPI35172.1 - 1.2e-16 60.8 0.0 2.7e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain Mcm10 PF09332.6 KPI35172.1 - 0.01 15.2 4.3 0.083 12.2 0.0 2.2 2 0 0 2 2 2 0 Mcm10 replication factor Fungal_trans_2 PF11951.3 KPI35173.1 - 8.3e-24 83.8 0.0 2.2e-23 82.5 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI35173.1 - 0.00029 20.6 6.6 0.00059 19.6 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 KPI35174.1 - 9.9e-21 74.3 10.7 5.2e-19 68.7 7.4 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MMR_HSR1 PF01926.18 KPI35174.1 - 2.6e-06 27.3 0.0 2.5e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KPI35174.1 - 2.3e-05 23.6 0.1 3.9e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ATP1G1_PLM_MAT8 PF02038.11 KPI35174.1 - 0.11 11.5 0.2 0.49 9.4 0.0 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Dynamin_N PF00350.18 KPI35174.1 - 0.22 11.3 1.5 3.5 7.4 0.0 2.8 2 1 0 3 3 3 0 Dynamin family DUF87 PF01935.12 KPI35174.1 - 0.3 10.8 0.8 0.62 9.8 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 adh_short PF00106.20 KPI35176.1 - 1.7e-28 99.6 1.0 2.2e-28 99.2 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI35176.1 - 2.2e-22 79.9 0.2 2.9e-22 79.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI35176.1 - 1.2e-11 44.5 0.9 1.9e-11 43.9 0.4 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KPI35176.1 - 0.0019 17.9 0.3 0.0031 17.1 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KPI35176.1 - 0.014 15.0 0.2 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Med17 PF10156.4 KPI35176.1 - 0.036 12.3 0.0 0.049 11.8 0.0 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex NAD_binding_10 PF13460.1 KPI35176.1 - 0.038 13.9 0.3 0.63 10.0 0.1 2.2 2 1 0 2 2 2 0 NADH(P)-binding DUF3425 PF11905.3 KPI35177.1 - 7.5e-24 84.1 0.2 1.1e-23 83.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Histone PF00125.19 KPI35178.1 - 3.8e-22 78.1 0.2 5.3e-22 77.7 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KPI35178.1 - 0.00016 21.6 0.0 0.00016 21.6 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KPI35178.1 - 0.00033 20.8 0.0 0.00057 20.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 KPI35178.1 - 0.042 13.3 0.2 0.069 12.6 0.0 1.5 2 0 0 2 2 2 0 Replication protein C N-terminal domain DUF1018 PF06252.7 KPI35178.1 - 0.076 13.5 0.6 0.16 12.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) Taq-exonuc PF09281.5 KPI35178.1 - 0.17 11.9 1.3 0.86 9.7 0.0 2.0 2 0 0 2 2 2 0 Taq polymerase, exonuclease Gpi1 PF05024.10 KPI35179.1 - 5e-62 208.9 10.6 5e-62 208.9 7.3 1.9 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) RRN7 PF11781.3 KPI35180.1 - 0.0041 16.5 0.6 0.0073 15.7 0.4 1.5 1 1 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 CpXC PF14353.1 KPI35180.1 - 0.015 15.2 0.0 0.017 15.0 0.0 1.0 1 0 0 1 1 1 0 CpXC protein DNA_RNApol_7kD PF03604.8 KPI35180.1 - 0.1 12.0 1.0 0.72 9.3 0.1 2.1 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit FUR PF01475.14 KPI35180.1 - 0.16 11.8 1.4 0.37 10.7 0.1 1.8 1 1 1 2 2 2 0 Ferric uptake regulator family RecR PF02132.10 KPI35180.1 - 0.44 10.0 2.5 1.8 8.0 0.1 2.2 2 0 0 2 2 2 0 RecR protein zf-ribbon_3 PF13248.1 KPI35180.1 - 0.78 9.0 3.8 6.3 6.1 3.2 2.0 1 1 1 2 2 2 0 zinc-ribbon domain zf-CCHC_6 PF15288.1 KPI35180.1 - 4.3 7.0 6.0 0.5 10.0 1.1 1.7 2 0 0 2 2 2 0 Zinc knuckle Mannosyl_trans3 PF11051.3 KPI35181.1 - 2.2e-41 141.9 0.1 2.5e-40 138.5 0.1 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative PipA PF07108.6 KPI35181.1 - 0.055 12.8 0.9 0.16 11.3 0.2 1.9 2 0 0 2 2 2 0 PipA protein FAD_binding_3 PF01494.14 KPI35182.1 - 1.7e-09 37.2 0.0 0.0004 19.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KPI35182.1 - 0.0001 22.2 0.0 0.00027 20.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI35182.1 - 0.00094 18.1 0.2 0.011 14.6 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KPI35182.1 - 0.0057 15.3 0.1 0.016 13.8 0.1 1.7 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.1 KPI35182.1 - 0.013 15.2 0.1 0.026 14.2 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KPI35182.1 - 0.051 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI35182.1 - 0.096 13.0 0.0 0.74 10.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Histone PF00125.19 KPI35183.1 - 8.3e-26 89.9 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KPI35183.1 - 1.2e-05 25.2 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ApbA_C PF08546.6 KPI35184.1 - 2.9e-30 104.8 0.0 4.7e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KPI35184.1 - 6.4e-29 100.3 0.0 8.4e-29 99.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF905 PF06006.7 KPI35185.1 - 0.035 13.4 0.1 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) OsmC PF02566.14 KPI35185.1 - 0.075 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 OsmC-like protein Fungal_trans_2 PF11951.3 KPI35187.1 - 8.1e-12 44.4 0.2 1.3e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Helicase_C_2 PF13307.1 KPI35188.1 - 5e-55 185.9 0.2 1.8e-54 184.1 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 KPI35188.1 - 2.2e-47 160.6 0.0 3.7e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 KPI35188.1 - 0.0034 16.9 0.0 2.1 7.8 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 KPI35188.1 - 0.017 14.9 0.0 3.3 7.4 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KPI35188.1 - 0.059 13.5 0.3 9.3 6.4 0.3 3.2 2 1 0 2 2 2 0 AAA domain Chromate_transp PF02417.10 KPI35189.1 - 2.3e-48 164.0 34.4 7.4e-29 100.5 7.3 3.4 4 0 0 4 4 4 3 Chromate transporter CcmH PF03918.9 KPI35189.1 - 7.5 5.5 6.9 3.7 6.5 0.0 3.1 3 0 0 3 3 3 0 Cytochrome C biogenesis protein RTA1 PF04479.8 KPI35191.1 - 1.6e-36 125.9 3.5 2.6e-36 125.2 2.4 1.2 1 0 0 1 1 1 1 RTA1 like protein AA_permease_2 PF13520.1 KPI35192.1 - 1.2e-53 182.1 61.5 1.6e-53 181.8 42.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI35192.1 - 6.6e-25 87.3 52.8 9.2e-25 86.9 36.6 1.1 1 0 0 1 1 1 1 Amino acid permease YrhC PF14143.1 KPI35192.1 - 0.089 12.7 1.3 0.6 10.1 0.9 2.5 1 0 0 1 1 1 0 YrhC-like protein PufQ PF05398.6 KPI35192.1 - 0.16 12.0 0.2 0.16 12.0 0.1 2.9 3 0 0 3 3 3 0 PufQ cytochrome subunit Sugar_tr PF00083.19 KPI35193.1 - 6.3e-99 331.5 25.9 7.2e-99 331.3 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI35193.1 - 3.6e-30 104.8 56.3 1.1e-27 96.7 21.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KPI35193.1 - 0.00048 18.4 2.2 0.00072 17.8 1.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pyr_redox_3 PF13738.1 KPI35195.1 - 1.1e-28 100.6 0.0 2.9e-28 99.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI35195.1 - 1.5e-11 43.2 0.0 6.8e-11 41.0 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KPI35195.1 - 2.4e-11 43.8 0.0 3.4e-06 27.0 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI35195.1 - 1.8e-07 31.0 0.0 4.1e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI35195.1 - 5.4e-06 25.5 0.0 3.3e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KPI35195.1 - 4.4e-05 22.5 1.4 0.14 11.0 0.3 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KPI35195.1 - 0.0054 15.6 0.2 0.0089 14.9 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KPI35195.1 - 0.0085 15.2 1.5 0.017 14.2 0.0 2.1 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.19 KPI35195.1 - 0.012 14.5 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 KPI35195.1 - 0.02 14.6 6.0 0.52 10.0 1.0 3.5 3 1 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 KPI35195.1 - 0.028 14.6 0.2 3.1 8.1 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 KPI35195.1 - 0.032 13.1 0.2 2.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 KPI35195.1 - 0.069 11.6 0.4 0.83 8.0 0.2 2.4 3 0 0 3 3 3 0 HI0933-like protein Shikimate_DH PF01488.15 KPI35195.1 - 0.097 12.7 0.1 8.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 KPI35196.1 - 1.2e-13 51.5 0.4 2.2e-13 50.7 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI35196.1 - 2.5e-12 47.0 0.0 5e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI35196.1 - 2.7e-12 47.0 0.1 7.5e-12 45.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI35196.1 - 1.1e-08 34.9 0.1 1.5e-08 34.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI35196.1 - 2.4e-08 34.3 0.2 9.5e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI35196.1 - 2.8e-07 30.5 0.1 5.2e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI35196.1 - 3.3e-07 30.0 0.0 4.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KPI35196.1 - 4.1e-06 26.2 0.0 6.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KPI35196.1 - 8e-06 25.1 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 KPI35196.1 - 3.2e-05 23.3 0.0 5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_3 PF01596.12 KPI35196.1 - 0.0077 15.2 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.8 KPI35196.1 - 0.024 13.7 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 KPI35196.1 - 0.05 12.6 0.0 0.087 11.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.10 KPI35196.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 NUDIX PF00293.23 KPI35197.1 - 3.3e-14 52.6 0.1 5.2e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 KPI35197.1 - 1.1e-09 38.4 0.0 2.6e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 KPI35197.1 - 4.1e-07 29.3 2.6 8.5e-07 28.3 1.8 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Sugar_tr PF00083.19 KPI35198.1 - 5.7e-126 420.7 32.2 6.9e-126 420.4 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI35198.1 - 1.4e-19 70.0 46.3 6.2e-19 67.9 27.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane_6 PF06182.6 KPI35199.1 - 0.26 10.8 5.4 0.27 10.7 0.1 2.8 3 0 0 3 3 3 0 ABC-2 family transporter protein Herpes_capsid PF06112.6 KPI35201.1 - 0.47 10.4 19.7 0.064 13.3 1.2 2.1 1 1 1 2 2 2 0 Gammaherpesvirus capsid protein DUF605 PF04652.11 KPI35201.1 - 1.5 8.1 17.7 1.7 7.9 12.2 1.1 1 0 0 1 1 1 0 Vta1 like Man-6-P_recep PF02157.10 KPI35202.1 - 1.2e-14 54.0 0.0 1.8e-14 53.4 0.0 1.3 1 1 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 KPI35202.1 - 0.00016 21.0 0.2 0.00037 19.8 0.1 1.7 1 1 0 1 1 1 1 Autophagy-related protein 27 BAR_2 PF10455.4 KPI35202.1 - 0.0035 16.3 0.1 0.0049 15.8 0.1 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking CIMR PF00878.13 KPI35202.1 - 0.0052 16.5 0.1 0.037 13.7 0.0 2.0 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat RNA_GG_bind PF10258.4 KPI35202.1 - 0.023 14.3 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 PHAX RNA-binding domain Complex1_LYR PF05347.10 KPI35203.1 - 1.8e-07 30.8 1.4 2.7e-07 30.2 1.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KPI35203.1 - 3.9e-05 23.7 0.6 6.2e-05 23.1 0.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Fungal_trans PF04082.13 KPI35204.1 - 3.7e-24 85.0 0.0 6.9e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI35204.1 - 1.4e-09 37.7 10.2 2.2e-09 37.0 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase_3 PF13468.1 KPI35205.1 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain adh_short_C2 PF13561.1 KPI35206.1 - 4.8e-19 69.0 0.0 6.5e-19 68.6 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI35206.1 - 1.6e-07 31.4 0.0 2.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI35206.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 KR domain Sel1 PF08238.7 KPI35207.1 - 4.1e-22 78.1 22.9 1.7e-09 38.0 0.4 7.2 7 0 0 7 7 7 6 Sel1 repeat TPR_2 PF07719.12 KPI35207.1 - 3 7.9 8.0 1 9.4 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KPI35207.1 - 4.2 7.1 7.6 1 9.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat A_deamin PF02137.13 KPI35208.1 - 1.1e-35 123.5 0.0 1.3e-35 123.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF3328 PF11807.3 KPI35209.1 - 1.4e-55 188.3 0.9 1.8e-55 187.9 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) ApoL PF05461.6 KPI35210.1 - 0.068 12.4 0.1 0.082 12.1 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein L UCR_Fe-S_N PF10399.4 KPI35210.1 - 2.9 7.1 8.3 0.16 11.1 1.6 2.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Aldedh PF00171.17 KPI35211.1 - 5.1e-68 229.4 0.0 2.1e-62 211.0 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Peptidase_C54 PF03416.14 KPI35213.1 - 2.8e-92 308.8 0.0 3.5e-92 308.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 ERG4_ERG24 PF01222.12 KPI35214.1 - 7.1e-121 403.7 2.5 9.4e-99 330.8 0.1 2.0 2 0 0 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family Aldedh PF00171.17 KPI35216.1 - 1.2e-150 501.8 0.0 1.4e-150 501.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CLU PF13236.1 KPI35217.1 - 1.6e-69 233.7 0.2 4.4e-56 189.7 0.0 2.5 1 1 1 2 2 2 2 Clustered mitochondria eIF3_p135 PF12807.2 KPI35217.1 - 7.1e-51 172.5 0.0 3.3e-50 170.3 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 KPI35217.1 - 1e-30 105.4 6.2 7.2e-10 38.6 0.0 4.0 1 1 4 5 5 5 5 Tetratricopeptide repeat CLU_N PF15044.1 KPI35217.1 - 2e-27 95.1 1.2 5.4e-27 93.7 0.9 1.8 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 KPI35217.1 - 9.8e-17 60.2 0.1 0.00028 20.7 0.0 5.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KPI35217.1 - 4.3e-06 26.2 0.6 5.6 7.1 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KPI35217.1 - 0.00088 19.8 0.6 13 6.6 0.0 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat UBX PF00789.15 KPI35217.1 - 0.013 15.5 0.3 0.12 12.5 0.1 2.4 2 0 0 2 2 2 0 UBX domain TPR_8 PF13181.1 KPI35217.1 - 0.014 15.0 0.9 11 6.1 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF727 PF05303.7 KPI35217.1 - 0.037 13.8 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF727) adh_short_C2 PF13561.1 KPI35218.1 - 3.7e-30 105.4 0.1 4.8e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI35218.1 - 6e-28 97.8 2.3 8.1e-28 97.4 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI35218.1 - 3.4e-06 26.8 1.0 5.6e-06 26.1 0.7 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI35218.1 - 0.00042 19.8 0.0 0.00064 19.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KPI35218.1 - 0.065 12.8 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_16 PF13191.1 KPI35220.1 - 0.00024 21.1 0.2 0.0081 16.1 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain ATP-synt_ab PF00006.20 KPI35220.1 - 0.019 14.4 0.1 0.61 9.5 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 KPI35220.1 - 0.026 14.2 0.1 0.06 13.0 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 KPI35220.1 - 0.027 13.8 0.1 0.1 12.0 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 KPI35220.1 - 0.028 13.9 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 KPI35220.1 - 0.034 13.2 0.4 0.079 12.0 0.1 1.7 2 0 0 2 2 2 0 KaiC MobB PF03205.9 KPI35220.1 - 0.04 13.6 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KPI35220.1 - 0.043 14.3 0.5 2.8 8.4 0.0 2.5 1 1 0 2 2 2 0 Miro-like protein ABC_tran PF00005.22 KPI35220.1 - 0.045 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.8 KPI35220.1 - 0.065 12.1 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) GFO_IDH_MocA PF01408.17 KPI35221.1 - 7.2e-28 97.5 0.4 9.9e-28 97.0 0.2 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KPI35221.1 - 3.1e-14 52.7 0.0 6.3e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 KPI35221.1 - 0.0014 18.8 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.14 KPI35221.1 - 0.021 15.2 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain DapB_N PF01113.15 KPI35221.1 - 0.029 14.2 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus AP_endonuc_2 PF01261.19 KPI35222.1 - 1.4e-23 83.2 0.0 5.5e-23 81.3 0.0 1.8 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel PIG-P PF08510.7 KPI35223.1 - 1.2e-40 138.0 0.2 5.9e-40 135.7 0.1 2.0 1 1 0 1 1 1 1 PIG-P U79_P34 PF03064.11 KPI35223.1 - 0.0028 17.2 6.2 0.0042 16.6 4.3 1.3 1 0 0 1 1 1 1 HSV U79 / HCMV P34 Vfa1 PF08432.5 KPI35223.1 - 0.12 12.3 5.9 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF2763 PF10961.3 KPI35224.1 - 1.6 9.1 5.0 1.5 9.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) DUF3405 PF11885.3 KPI35225.1 - 3e-146 487.5 0.7 3.6e-145 483.9 0.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) MFS_1 PF07690.11 KPI35225.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily zf-C2H2_jaz PF12171.3 KPI35226.1 - 6.8e-06 26.0 3.9 1.4e-05 25.0 2.7 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KPI35226.1 - 0.0053 16.9 0.7 0.0088 16.2 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Lipoprotein_19 PF13617.1 KPI35226.1 - 0.022 14.3 0.2 0.038 13.6 0.1 1.4 1 0 0 1 1 1 0 YnbE-like lipoprotein zf-C2H2 PF00096.21 KPI35226.1 - 0.045 14.0 0.9 0.045 14.0 0.6 1.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI35226.1 - 0.059 13.7 0.6 0.12 12.7 0.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Tup_N PF08581.5 KPI35226.1 - 0.061 13.5 0.7 0.061 13.5 0.5 2.0 2 0 0 2 2 2 0 Tup N-terminal Img2 PF05046.9 KPI35228.1 - 8.3e-20 70.8 0.0 1.3e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Opi1 PF08618.5 KPI35228.1 - 0.046 12.6 0.4 0.061 12.2 0.3 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 Ndc1_Nup PF09531.5 KPI35228.1 - 0.11 10.9 0.6 0.13 10.6 0.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hamartin PF04388.7 KPI35228.1 - 2.1 6.8 4.6 2.7 6.5 3.2 1.1 1 0 0 1 1 1 0 Hamartin protein 2OG-FeII_Oxy PF03171.15 KPI35229.1 - 3e-15 56.2 0.0 7.2e-15 55.0 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KPI35229.1 - 3.1e-13 50.2 0.0 5e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Sec23_trunk PF04811.10 KPI35230.1 - 1.8e-71 240.3 0.0 2.8e-71 239.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KPI35230.1 - 8e-24 83.0 0.8 4.8e-23 80.5 0.0 2.7 3 0 0 3 3 3 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 KPI35230.1 - 8e-18 63.7 4.3 1.4e-17 62.9 3.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 KPI35230.1 - 2.4e-17 63.2 0.0 6.1e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KPI35230.1 - 5.7e-10 38.7 0.0 1.6e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat zf-DHHC PF01529.15 KPI35231.1 - 1.5 8.2 6.3 2.3 7.5 4.4 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase PIG-P PF08510.7 KPI35231.1 - 9.1 5.9 11.2 2.9 7.5 0.4 2.3 1 1 1 2 2 2 0 PIG-P Amidohydro_1 PF01979.15 KPI35232.1 - 6e-21 75.4 0.0 7.7e-14 52.0 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KPI35232.1 - 3.1e-17 63.5 1.0 5.2e-17 62.7 0.7 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KPI35232.1 - 3.1e-09 36.4 0.4 1.3e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KPI35232.1 - 3.8e-06 26.3 0.0 0.0053 16.0 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Glyco_hydro_26 PF02156.10 KPI35232.1 - 0.25 10.7 0.0 0.48 9.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 PT-VENN PF04829.8 KPI35233.1 - 2.9 7.5 4.9 6.1 6.4 3.4 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif NPCC PF08058.6 KPI35234.1 - 5e-18 65.3 1.1 2.2e-17 63.2 0.7 1.9 1 1 0 1 1 1 1 Nuclear pore complex component CytochromB561_N PF09786.4 KPI35234.1 - 0.00094 17.7 0.0 0.0013 17.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal FAD_binding_4 PF01565.18 KPI35235.1 - 7.4e-22 77.3 1.3 1.3e-21 76.5 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KPI35235.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like Peptidase_S15 PF02129.13 KPI35236.1 - 6.7e-41 140.4 0.1 1.7e-39 135.8 0.0 2.2 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KPI35236.1 - 4.8e-19 69.1 0.0 6.9e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Cupin_2 PF07883.6 KPI35238.1 - 4.6e-06 26.0 0.0 6.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KPI35238.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.7 KPI35238.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) MOSC PF03473.12 KPI35239.1 - 6.8e-19 67.6 0.0 1.1e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 KPI35239.1 - 4.3e-09 36.1 0.0 7.1e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Pkinase PF00069.20 KPI35240.1 - 2.6e-74 249.6 0.0 3.2e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI35240.1 - 9.5e-32 110.0 0.0 1.3e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI35240.1 - 0.00077 18.5 0.0 0.002 17.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KPI35240.1 - 0.0018 17.3 0.1 0.003 16.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KPI35240.1 - 0.014 15.1 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KPI35240.1 - 0.045 12.5 0.1 0.068 11.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 UDP-g_GGTase PF06427.6 KPI35241.1 - 2.9e-63 212.9 0.1 2e-62 210.2 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KPI35241.1 - 4.4e-05 22.9 0.1 7.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF1416 PF07210.7 KPI35241.1 - 0.05 13.2 0.0 0.77 9.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1416) BCS1_N PF08740.6 KPI35242.1 - 8.9e-32 110.2 1.4 1.4e-31 109.5 1.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KPI35242.1 - 6.6e-16 58.7 0.0 2.4e-07 31.0 0.0 2.7 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KPI35242.1 - 0.00068 20.4 0.1 0.0049 17.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Acetyltransf_5 PF13444.1 KPI35242.1 - 0.073 13.6 0.2 0.32 11.5 0.1 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain RuvB_N PF05496.7 KPI35242.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus KaiC PF06745.8 KPI35242.1 - 0.2 10.7 0.0 0.38 9.8 0.0 1.4 1 0 0 1 1 1 0 KaiC Asparaginase PF00710.15 KPI35243.1 - 5.4e-92 308.0 0.0 3.3e-91 305.4 0.0 1.9 1 1 0 1 1 1 1 Asparaginase NmrA PF05368.8 KPI35243.1 - 8.2e-54 182.3 0.0 1.4e-53 181.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI35243.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding TRI12 PF06609.8 KPI35244.1 - 5.8e-22 77.6 25.9 8.6e-22 77.0 17.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI35244.1 - 7.9e-22 77.4 49.3 7.9e-22 77.4 34.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2077 PF09850.4 KPI35244.1 - 0.38 10.1 1.4 3 7.1 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) PrgI PF12666.2 KPI35244.1 - 1.6 8.8 13.9 1.3 9.1 0.1 4.8 4 0 0 4 4 4 0 PrgI family protein Glug PF07581.7 KPI35244.1 - 1.7 9.0 7.5 9.4 6.6 5.2 2.4 1 0 0 1 1 1 0 The GLUG motif ECH PF00378.15 KPI35245.1 - 7.8e-20 71.0 0.1 3.5e-17 62.3 0.1 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family VSP PF03302.8 KPI35247.1 - 0.034 12.7 0.1 0.046 12.3 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DAP10 PF07213.6 KPI35247.1 - 0.039 13.7 0.3 0.2 11.4 0.1 2.2 2 0 0 2 2 2 0 DAP10 membrane protein DUF2668 PF10873.3 KPI35247.1 - 0.082 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) Amnionless PF14828.1 KPI35247.1 - 0.15 10.4 0.0 0.25 9.7 0.0 1.3 1 0 0 1 1 1 0 Amnionless DUF3042 PF11240.3 KPI35247.1 - 1.4 8.7 5.4 2.6 7.9 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Microtub_assoc PF07989.6 KPI35248.1 - 7.8e-25 86.5 3.7 7.8e-25 86.5 2.5 14.3 9 4 6 15 15 15 1 Microtubule associated PACT_coil_coil PF10495.4 KPI35248.1 - 1.7e-11 43.8 2.3 3e-11 43.0 0.3 2.5 2 0 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.4 KPI35248.1 - 0.0058 16.4 16.5 0.0058 16.4 11.5 12.3 2 2 11 13 13 13 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KPI35248.1 - 0.41 9.7 71.5 0.019 14.1 2.9 7.7 1 1 6 8 8 8 0 Reovirus sigma C capsid protein WD40_alt PF14077.1 KPI35248.1 - 7.8 6.2 15.7 13 5.5 0.8 5.1 5 0 0 5 5 5 0 Alternative WD40 repeat motif APH PF01636.18 KPI35249.1 - 0.0061 16.3 0.0 0.084 12.5 0.0 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family LETM1 PF07766.8 KPI35251.1 - 0.0079 15.2 0.2 0.017 14.1 0.1 1.6 1 1 0 1 1 1 1 LETM1-like protein TPR_11 PF13414.1 KPI35253.1 - 5.8e-12 45.0 19.4 2.4e-06 27.0 0.2 5.7 4 2 1 5 5 5 3 TPR repeat TPR_2 PF07719.12 KPI35253.1 - 1.6e-08 33.8 25.4 0.0015 18.3 0.2 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 KPI35253.1 - 2.2e-06 27.4 12.8 0.0072 16.2 0.3 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KPI35253.1 - 7.9e-06 25.2 13.5 0.017 14.8 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KPI35253.1 - 1.2e-05 25.8 21.4 0.089 13.4 0.3 6.8 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 KPI35253.1 - 5.2e-05 22.7 12.7 0.87 9.5 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 KPI35253.1 - 0.00017 21.6 7.9 0.12 12.9 0.5 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KPI35253.1 - 0.00021 21.2 2.4 5.5 7.4 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KPI35253.1 - 0.0016 18.8 18.4 9.7 7.1 0.1 8.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.1 KPI35253.1 - 0.0025 18.1 19.0 1.2 9.5 1.2 7.2 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.23 KPI35253.1 - 0.0067 16.0 20.9 0.56 9.9 0.1 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat CHRD PF07452.7 KPI35254.1 - 0.00048 20.7 0.0 0.0034 17.9 0.0 2.1 1 1 0 1 1 1 1 CHRD domain MFS_1 PF07690.11 KPI35256.1 - 1.8e-26 92.7 42.7 2.8e-14 52.6 10.0 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI35256.1 - 0.00055 18.6 0.1 0.00055 18.6 0.1 3.5 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.2 KPI35256.1 - 0.0019 17.9 4.6 0.27 11.0 0.0 3.8 4 0 0 4 4 4 2 MFS_1 like family Zn-ribbon_8 PF09723.5 KPI35257.1 - 0.15 12.0 0.8 3.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Herpes_UL32 PF06070.6 KPI35257.1 - 0.64 8.3 4.8 0.69 8.3 3.3 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Period_C PF12114.3 KPI35257.1 - 2.5 7.6 8.5 3.6 7.1 5.9 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Macoilin PF09726.4 KPI35257.1 - 4.6 5.3 6.8 4.9 5.2 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1804 PF08822.6 KPI35258.1 - 0.087 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Glyco_hydro_67M PF07488.7 KPI35259.1 - 3.3e-141 469.9 0.1 4.4e-141 469.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 KPI35259.1 - 8.1e-87 290.3 0.5 1.2e-86 289.7 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 KPI35259.1 - 1.3e-28 99.4 0.0 2.3e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 KPI35259.1 - 0.0042 17.6 0.1 0.01 16.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Fungal_trans PF04082.13 KPI35261.1 - 2.2e-15 56.2 0.1 4.4e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI35261.1 - 8.7e-10 38.3 7.1 2.1e-09 37.1 4.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KPI35261.1 - 0.18 11.9 8.3 0.62 10.2 5.8 1.9 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region FAD_binding_3 PF01494.14 KPI35262.1 - 1.5e-36 126.2 0.0 3.3e-21 75.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain TRI12 PF06609.8 KPI35263.1 - 7.1e-17 60.8 19.7 2.6e-14 52.3 7.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI35263.1 - 9.9e-12 44.2 64.2 1.6e-09 37.0 14.4 3.7 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF1772 PF08592.6 KPI35265.1 - 2.2e-18 66.3 0.4 3.8e-18 65.5 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) SlyX PF04102.7 KPI35266.1 - 0.011 16.1 3.4 0.063 13.6 0.3 2.5 2 0 0 2 2 2 0 SlyX XhlA PF10779.4 KPI35266.1 - 0.021 14.7 1.1 0.051 13.5 0.8 1.7 1 0 0 1 1 1 0 Haemolysin XhlA DUF4407 PF14362.1 KPI35266.1 - 0.058 12.3 1.0 0.073 12.0 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF641 PF04859.7 KPI35266.1 - 0.069 12.8 0.8 0.11 12.2 0.6 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Myosin_tail_1 PF01576.14 KPI35266.1 - 0.12 10.1 3.5 0.15 9.7 2.5 1.1 1 0 0 1 1 1 0 Myosin tail Cluap1 PF10234.4 KPI35266.1 - 0.12 11.5 2.6 0.16 11.1 1.8 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Prefoldin_2 PF01920.15 KPI35266.1 - 0.18 11.5 2.7 1.6 8.5 1.9 2.1 1 1 0 1 1 1 0 Prefoldin subunit DUF3391 PF11871.3 KPI35266.1 - 0.2 11.8 2.9 0.32 11.1 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF837 PF05769.6 KPI35266.1 - 0.22 11.0 3.8 1 8.8 2.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF837) Atg14 PF10186.4 KPI35266.1 - 0.37 9.7 4.2 0.45 9.4 2.9 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF883 PF05957.8 KPI35266.1 - 0.4 11.1 3.4 1.7 9.1 2.3 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.7 KPI35266.1 - 0.5 10.1 4.4 0.46 10.3 2.4 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 KPI35266.1 - 0.66 10.1 3.5 0.56 10.3 1.4 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Med9 PF07544.8 KPI35266.1 - 0.66 9.7 5.9 1.9 8.3 0.8 3.0 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 BLOC1_2 PF10046.4 KPI35266.1 - 0.7 10.0 4.2 0.44 10.7 1.1 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HisKA_3 PF07730.8 KPI35266.1 - 0.73 10.2 3.7 1.2 9.5 0.6 2.3 1 1 1 2 2 2 0 Histidine kinase DUF2968 PF11180.3 KPI35266.1 - 4.4 6.6 10.0 0.93 8.8 4.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Abhydrolase_6 PF12697.2 KPI35267.1 - 4.2e-15 56.2 0.1 1.2e-14 54.8 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.6 KPI35267.1 - 5.5e-15 54.8 0.0 6.9e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 KPI35267.1 - 1.8e-12 47.2 0.0 3.2e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KPI35267.1 - 6.1e-07 29.1 0.0 9.1e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 KPI35267.1 - 7.1e-06 25.3 0.2 2.4e-05 23.6 0.0 2.0 2 1 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.15 KPI35267.1 - 7.1e-06 25.6 0.0 8.8e-05 22.0 0.0 2.3 2 1 0 2 2 2 1 Putative esterase BAAT_C PF08840.6 KPI35267.1 - 0.00033 20.4 0.0 0.00085 19.0 0.0 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 KPI35267.1 - 0.0012 18.2 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 KPI35267.1 - 0.0029 17.2 0.5 0.0099 15.4 0.1 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KPI35267.1 - 0.0071 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 KPI35267.1 - 0.0072 15.5 0.1 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 KPI35267.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AXE1 PF05448.7 KPI35267.1 - 0.031 12.7 0.0 0.057 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) MIT PF04212.13 KPI35267.1 - 0.11 12.3 1.0 0.19 11.6 0.7 1.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DivIC PF04977.10 KPI35269.1 - 0.036 13.5 0.3 0.059 12.8 0.2 1.3 1 0 0 1 1 1 0 Septum formation initiator Cortex-I_coil PF09304.5 KPI35269.1 - 0.049 13.6 0.7 0.093 12.7 0.5 1.5 1 1 0 1 1 1 0 Cortexillin I, coiled coil DUF3799 PF12684.2 KPI35269.1 - 0.051 12.9 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) Lactamase_B PF00753.22 KPI35270.1 - 1e-17 64.4 3.1 1.4e-17 63.9 2.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI35270.1 - 0.041 13.4 0.3 0.056 12.9 0.2 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain PDEase_II PF02112.10 KPI35270.1 - 0.06 12.2 0.0 0.17 10.7 0.0 1.6 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II Amidohydro_4 PF13147.1 KPI35271.1 - 3.1e-23 83.2 0.0 5.5e-22 79.0 0.0 3.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KPI35271.1 - 4.4e-15 56.1 0.0 1.1e-08 35.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KPI35271.1 - 1e-12 47.6 0.4 9e-12 44.6 0.2 2.5 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 KPI35271.1 - 0.0011 18.2 0.1 0.7 9.0 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family DUF4619 PF15398.1 KPI35271.1 - 0.23 10.8 0.0 0.64 9.3 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4619) SURF6 PF04935.7 KPI35272.1 - 5e-46 156.6 30.9 5e-46 156.6 21.5 3.4 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 KPI35272.1 - 1.3e-20 73.1 1.3 1.3e-20 73.1 0.9 8.1 5 2 3 8 8 8 1 60S ribosome biogenesis protein Rrp14 NMO PF03060.10 KPI35273.1 - 8.8e-56 189.4 1.6 2.8e-55 187.7 1.1 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KPI35273.1 - 2.9e-10 39.6 0.0 0.00015 20.7 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KPI35273.1 - 0.00017 20.5 0.2 0.00031 19.7 0.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF1902 PF08972.6 KPI35273.1 - 0.0072 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1902) His_biosynth PF00977.16 KPI35273.1 - 0.0093 15.2 0.1 0.041 13.1 0.1 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein Glu_synthase PF01645.12 KPI35273.1 - 0.018 13.9 0.7 0.045 12.6 0.5 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase Asp PF00026.18 KPI35274.1 - 1.3e-58 198.7 4.7 4.7e-58 196.9 3.2 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KPI35274.1 - 3.8e-08 33.4 0.0 9e-07 28.9 0.0 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KPI35274.1 - 0.00091 19.6 1.8 0.1 13.1 0.3 3.2 2 1 0 2 2 2 1 Aspartyl protease SGT1 PF07093.6 KPI35275.1 - 2.9e-125 418.9 32.8 3.1e-123 412.2 22.7 2.0 1 1 0 1 1 1 1 SGT1 protein GMC_oxred_N PF00732.14 KPI35277.1 - 6.3e-58 196.2 0.0 5.8e-42 143.8 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI35277.1 - 7.2e-36 123.6 0.0 1.5e-35 122.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KPI35277.1 - 6.1e-05 22.0 0.3 0.0013 17.6 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI35277.1 - 0.0016 18.4 0.1 0.0043 17.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KPI35277.1 - 0.0018 17.2 0.4 0.004 16.1 0.2 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KPI35277.1 - 0.0037 16.1 0.0 0.085 11.6 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KPI35277.1 - 0.15 12.4 0.4 6.9 7.1 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Vma12 PF11712.3 KPI35278.1 - 1.6e-31 108.9 0.0 2.5e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Oxidored_q2 PF00420.19 KPI35278.1 - 0.0075 15.8 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Lung_7-TM_R PF06814.8 KPI35278.1 - 0.1 11.5 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Lung seven transmembrane receptor Clr5 PF14420.1 KPI35279.1 - 3.6e-19 68.3 1.0 7e-19 67.4 0.7 1.5 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 KPI35279.1 - 5.1e-07 29.5 3.7 0.017 15.0 0.2 3.9 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KPI35279.1 - 1.4e-06 27.8 0.2 0.00027 20.4 0.1 3.1 2 1 1 3 3 3 1 TPR repeat TPR_2 PF07719.12 KPI35279.1 - 0.00032 20.3 2.3 1.8 8.6 0.1 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KPI35279.1 - 0.019 14.5 0.1 1.7 8.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KPI35279.1 - 0.031 14.8 0.7 3 8.7 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat HTH_33 PF13592.1 KPI35279.1 - 0.051 13.1 0.1 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn helix ST7 PF04184.7 KPI35279.1 - 0.073 11.3 0.2 0.11 10.7 0.1 1.2 1 0 0 1 1 1 0 ST7 protein TPR_7 PF13176.1 KPI35279.1 - 0.077 12.8 0.3 0.56 10.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1996 PF09362.5 KPI35280.1 - 1.3e-73 247.5 0.2 2.1e-73 246.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Pyr_redox_3 PF13738.1 KPI35281.1 - 0.004 17.2 0.0 0.0092 16.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI35281.1 - 0.025 14.3 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding RTA1 PF04479.8 KPI35282.1 - 1.7e-27 96.3 4.0 9.5e-27 93.9 2.9 1.9 1 1 1 2 2 2 1 RTA1 like protein PalH PF08733.5 KPI35282.1 - 0.32 9.8 4.5 0.046 12.5 0.6 1.4 2 0 0 2 2 2 0 PalH/RIM21 zf-DHHC PF01529.15 KPI35282.1 - 0.48 9.7 2.5 0.8 9.0 0.2 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase p450 PF00067.17 KPI35283.1 - 4.7e-68 229.8 0.0 5.7e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF3_N PF09440.5 KPI35284.1 - 7.9e-38 129.6 0.5 7.9e-38 129.6 0.4 2.3 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KPI35284.1 - 2.3e-13 50.3 0.0 6.2e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 KPI35284.1 - 0.023 14.4 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Xan_ur_permease PF00860.15 KPI35286.1 - 4.7e-65 219.5 37.0 1.2e-63 214.9 25.7 2.0 1 1 0 1 1 1 1 Permease family p450 PF00067.17 KPI35287.1 - 3.8e-62 210.3 0.0 4.4e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CoA_transf_3 PF02515.12 KPI35288.1 - 2.3e-26 92.2 0.0 1.7e-24 86.1 0.0 2.8 2 1 0 2 2 2 2 CoA-transferase family III SWIRM PF04433.12 KPI35289.1 - 6.4e-34 115.9 0.1 1.4e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 KPI35289.1 - 1.7e-07 31.1 0.0 4.4e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KPI35289.1 - 4.8e-06 26.5 0.0 9.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Hid1 PF12722.2 KPI35290.1 - 1.5e-246 820.4 0.0 6.1e-238 791.9 0.0 2.2 1 1 0 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KPI35290.1 - 8.1e-87 291.9 0.0 1.3e-86 291.2 0.0 1.3 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Fungal_trans PF04082.13 KPI35291.1 - 3e-34 118.0 1.1 8.9e-34 116.5 0.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zwint PF15556.1 KPI35291.1 - 0.19 10.9 2.2 0.21 10.8 0.5 1.7 2 0 0 2 2 2 0 ZW10 interactor F-box PF00646.28 KPI35292.1 - 5.4e-06 25.9 0.3 1.2e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KPI35292.1 - 0.011 15.4 0.3 0.029 14.1 0.0 1.9 2 0 0 2 2 2 0 F-box-like Abhydrolase_6 PF12697.2 KPI35293.1 - 9.4e-05 22.3 0.2 0.00018 21.4 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family zf-C2H2_4 PF13894.1 KPI35293.1 - 0.0011 19.1 1.3 0.0023 18.1 0.9 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger DUF900 PF05990.7 KPI35293.1 - 0.0026 17.1 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.9 KPI35293.1 - 0.006 15.9 0.1 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) zf-H2C2_2 PF13465.1 KPI35293.1 - 0.01 16.0 1.3 1.8 8.9 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-Di19 PF05605.7 KPI35293.1 - 0.019 15.0 0.5 0.034 14.2 0.3 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Abhydrolase_5 PF12695.2 KPI35293.1 - 0.029 14.1 0.0 0.061 13.0 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 KPI35293.1 - 0.045 13.3 0.1 0.073 12.6 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein zf-C2H2 PF00096.21 KPI35293.1 - 0.43 11.0 1.7 0.8 10.1 1.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3176 PF11374.3 KPI35294.1 - 5.1e-29 100.3 0.5 5.1e-29 100.3 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Myb_DNA-bind_6 PF13921.1 KPI35296.1 - 6.3e-11 42.2 3.0 6.3e-11 42.2 2.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KPI35296.1 - 1.7e-06 27.9 4.2 0.001 19.0 0.5 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain zf-C2H2 PF00096.21 KPI35296.1 - 8.6e-06 25.8 5.3 0.035 14.4 0.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KPI35296.1 - 8.5e-05 22.5 2.7 0.055 13.6 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KPI35296.1 - 0.0014 18.7 0.9 0.0033 17.5 0.2 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KPI35296.1 - 0.0068 16.5 3.0 0.95 9.6 0.2 2.6 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KPI35296.1 - 0.047 14.0 3.4 2.8 8.4 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Elf1 PF05129.8 KPI35296.1 - 4.8 6.9 6.9 0.24 11.1 0.2 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Fungal_trans PF04082.13 KPI35297.1 - 6.5e-15 54.6 0.0 9.8e-15 54.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI35297.1 - 1.9e-08 34.0 11.0 5.4e-08 32.6 7.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_B561 PF03188.11 KPI35299.1 - 4.5e-08 33.0 9.0 4.5e-08 33.0 6.2 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KPI35299.1 - 0.00011 21.7 5.2 0.00011 21.7 3.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) SUR7 PF06687.7 KPI35299.1 - 4.3 6.8 10.3 0.26 10.8 1.8 2.1 1 1 1 2 2 2 0 SUR7/PalI family DUF4231 PF14015.1 KPI35299.1 - 4.4 7.3 12.9 3.7 7.5 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Motile_Sperm PF00635.21 KPI35300.1 - 6.1e-29 99.8 0.1 1.2e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF756 PF05506.7 KPI35300.1 - 0.018 15.5 0.0 0.05 14.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF756) COG5 PF10392.4 KPI35300.1 - 0.025 14.5 0.2 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF2077 PF09850.4 KPI35300.1 - 0.088 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) FliG_C PF01706.11 KPI35300.1 - 0.11 12.4 4.1 0.12 12.3 1.0 2.2 3 0 0 3 3 3 0 FliG C-terminal domain Golgin_A5 PF09787.4 KPI35300.1 - 0.13 10.7 5.7 0.18 10.2 4.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4164 PF13747.1 KPI35300.1 - 0.17 12.0 3.1 0.56 10.3 2.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF1192 PF06698.6 KPI35300.1 - 0.22 11.3 1.8 0.85 9.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF2562 PF10814.3 KPI35300.1 - 0.4 10.6 6.0 1.8 8.4 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) Glyco_hydro_35 PF01301.14 KPI35301.1 - 1.8e-85 287.0 0.3 2.8e-85 286.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KPI35301.1 - 1.2e-53 181.1 0.8 2.3e-53 180.2 0.6 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KPI35301.1 - 2.8e-20 72.6 1.0 2.8e-20 72.6 0.7 2.9 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KPI35301.1 - 1.2e-15 56.6 0.4 5e-15 54.6 0.0 2.3 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 p450 PF00067.17 KPI35302.1 - 3.2e-49 167.7 0.0 4.2e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CHAP PF05257.11 KPI35303.1 - 0.072 12.7 0.6 0.2 11.3 0.1 1.8 2 0 0 2 2 2 0 CHAP domain His_Phos_2 PF00328.17 KPI35304.1 - 4.6e-21 75.5 0.0 5.4e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 KPI35304.1 - 0.0041 17.2 0.0 0.0082 16.2 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M19 PF01244.16 KPI35305.1 - 2.6e-89 299.3 0.0 3.2e-89 299.0 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) OppC_N PF12911.2 KPI35305.1 - 0.19 11.1 0.5 0.48 9.8 0.3 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C LigB PF02900.13 KPI35307.1 - 3.1e-47 160.8 0.0 3.8e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase EAP30 PF04157.11 KPI35307.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family Gp_dh_C PF02800.15 KPI35308.1 - 2.3e-57 192.8 0.0 3.3e-57 192.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KPI35308.1 - 3.8e-46 156.7 0.2 7.7e-46 155.7 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 KPI35308.1 - 0.0029 17.5 0.3 0.0097 15.8 0.0 2.1 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 KPI35308.1 - 0.085 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ICL PF00463.16 KPI35309.1 - 1.7e-90 303.7 0.0 2.1e-90 303.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KPI35309.1 - 3.1e-09 36.4 0.0 5e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF2935 PF11155.3 KPI35309.1 - 0.00065 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2935) RNA_pol_L_2 PF13656.1 KPI35310.1 - 2.2e-24 84.6 0.0 3e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KPI35310.1 - 7.8e-10 37.7 0.0 1.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain UBA PF00627.26 KPI35311.1 - 2.8e-05 23.8 0.1 9.2e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain UBX PF00789.15 KPI35311.1 - 0.00048 20.1 0.2 0.0015 18.5 0.0 2.1 2 0 0 2 2 2 1 UBX domain THRAP3_BCLAF1 PF15440.1 KPI35311.1 - 0.095 11.3 31.4 0.12 11.0 21.7 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family MtrG PF04210.8 KPI35311.1 - 0.14 11.8 1.2 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G SOBP PF15279.1 KPI35311.1 - 1.2 9.4 9.3 1.5 9.1 6.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CpXC PF14353.1 KPI35311.1 - 6.6 6.7 10.9 31 4.5 7.5 2.2 1 1 0 1 1 1 0 CpXC protein BetaGal_dom4_5 PF13364.1 KPI35312.1 - 3e-21 75.7 0.1 4e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Syja_N PF02383.13 KPI35313.1 - 2.9e-84 282.5 0.0 4.5e-84 281.9 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 KPI35313.1 - 2.2e-26 93.3 0.1 4.1e-26 92.4 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.11 KPI35315.1 - 7.1e-25 87.4 17.9 8.9e-25 87.1 12.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI35315.1 - 1.9e-06 26.7 10.0 6.2e-06 25.0 7.2 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 KPI35315.1 - 0.015 15.1 0.3 0.04 13.7 0.2 1.8 1 0 0 1 1 1 0 MFS_1 like family UNC-93 PF05978.11 KPI35315.1 - 0.033 13.6 0.4 0.033 13.6 0.3 2.1 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 NmrA PF05368.8 KPI35316.1 - 8.6e-31 106.9 0.0 9.5e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KPI35316.1 - 6.5e-09 35.5 0.2 4.1e-07 29.6 0.3 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI35316.1 - 1e-08 35.3 0.1 3.4e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 KPI35316.1 - 1.4e-07 30.4 0.4 2.2e-07 29.8 0.3 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KPI35316.1 - 4.4e-06 26.7 0.4 4.4e-06 26.7 0.3 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KPI35316.1 - 6.8e-06 25.8 0.3 1.6e-05 24.6 0.2 1.6 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 KPI35316.1 - 8.2e-06 26.1 0.2 2.3e-05 24.6 0.1 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 KPI35316.1 - 0.00017 21.5 0.8 0.00036 20.4 0.5 1.6 1 0 0 1 1 1 1 TrkA-N domain Arg_repressor PF01316.16 KPI35316.1 - 0.012 15.1 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain Cas_Cas02710 PF09670.5 KPI35316.1 - 0.038 12.6 0.0 0.062 11.9 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) DXP_reductoisom PF02670.11 KPI35316.1 - 0.041 14.4 0.1 0.1 13.1 0.1 1.7 2 0 0 2 2 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Polysacc_synt_2 PF02719.10 KPI35316.1 - 0.046 12.6 0.3 0.068 12.0 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sua5_yciO_yrdC PF01300.13 KPI35317.1 - 0.00063 19.0 0.0 0.00075 18.7 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination Fungal_trans PF04082.13 KPI35318.1 - 6.2e-08 31.8 0.1 2.5e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Polysacc_deac_1 PF01522.16 KPI35320.1 - 4e-10 39.3 0.0 7.5e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Fungal_trans PF04082.13 KPI35321.1 - 7.3e-24 84.0 0.0 1.2e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 KPI35322.1 - 2.5e-11 43.7 0.0 5.1e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI35322.1 - 0.00036 20.2 0.0 0.0015 18.2 0.0 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI35322.1 - 0.014 14.8 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI35322.1 - 0.056 13.4 0.0 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 NADH(P)-binding Ferritin_2 PF13668.1 KPI35324.1 - 2.1e-16 60.1 0.0 4.1e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 KPI35324.1 - 0.09 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Rubrerythrin DAO PF01266.19 KPI35325.1 - 9.2e-39 133.3 4.1 1.5e-38 132.6 2.9 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KPI35325.1 - 1.5e-05 25.1 0.0 0.19 11.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI35325.1 - 0.0016 18.4 0.1 0.0042 17.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KPI35325.1 - 0.016 14.1 0.2 0.039 12.8 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 KPI35325.1 - 0.023 14.4 0.8 0.51 10.1 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 KPI35325.1 - 0.062 12.3 0.1 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Mqo PF06039.10 KPI35325.1 - 0.072 11.2 0.0 0.14 10.2 0.0 1.4 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) adh_short PF00106.20 KPI35326.1 - 2.7e-20 72.9 2.5 1.8e-18 67.0 0.3 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KPI35326.1 - 4.4e-08 32.9 0.4 8.9e-08 31.9 0.3 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI35326.1 - 0.00047 19.6 0.1 0.00059 19.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Toprim_3 PF13362.1 KPI35326.1 - 0.069 13.4 0.2 1.5 9.0 0.0 2.6 1 1 0 2 2 2 0 Toprim domain Transp_cyt_pur PF02133.10 KPI35327.1 - 4.1e-95 318.9 32.5 4.8e-95 318.6 22.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin His_Phos_2 PF00328.17 KPI35328.1 - 1.8e-37 129.4 0.0 2.9e-37 128.7 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pho88 PF10032.4 KPI35329.1 - 1.6e-79 265.6 0.1 1.8e-79 265.4 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) MFS_1 PF07690.11 KPI35330.1 - 5e-14 51.7 5.4 2.2e-07 29.9 1.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI35330.1 - 4.9e-07 28.6 5.6 5.5e-07 28.5 0.3 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter NMO PF03060.10 KPI35331.1 - 2.2e-20 73.1 2.4 2.2e-17 63.2 1.1 2.9 2 1 0 2 2 2 2 Nitronate monooxygenase Polysacc_deac_1 PF01522.16 KPI35331.1 - 0.0063 16.1 0.0 0.68 9.5 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide deacetylase Hist_deacetyl PF00850.14 KPI35333.1 - 2.7e-91 306.1 0.0 9.2e-91 304.3 0.0 1.7 2 0 0 2 2 2 1 Histone deacetylase domain Arb2 PF09757.4 KPI35333.1 - 2.7e-33 114.8 0.0 5e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Arb2 domain NYD-SP12_N PF15015.1 KPI35333.1 - 0.12 10.6 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal ADH_N PF08240.7 KPI35334.1 - 6.7e-10 38.6 0.0 1.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI35334.1 - 9.2e-09 34.9 0.0 1.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3185 PF11381.3 KPI35335.1 - 0.053 13.2 1.9 0.066 12.9 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) ATPase_gene1 PF09527.5 KPI35335.1 - 0.055 13.2 0.4 0.52 10.1 0.2 1.9 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) Antimicrobial20 PF08256.6 KPI35335.1 - 0.28 11.5 1.0 0.44 10.9 0.7 1.3 1 0 0 1 1 1 0 Aurein-like antibiotic peptide MFS_1 PF07690.11 KPI35336.1 - 1.4e-14 53.5 17.7 1.4e-14 53.5 12.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.11 KPI35337.1 - 6.1e-40 137.5 0.0 7.3e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lactamase_B PF00753.22 KPI35338.1 - 0.00038 20.1 0.6 0.00056 19.6 0.4 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI35338.1 - 0.0058 16.2 0.1 0.0091 15.5 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_trans_2_3 PF13632.1 KPI35339.1 - 4.2e-47 160.3 4.2 4.2e-47 160.3 2.9 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KPI35339.1 - 1.4e-06 28.3 0.0 2.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KPI35339.1 - 8.4e-06 25.5 0.2 7.4e-05 22.5 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KPI35339.1 - 0.0086 15.3 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 AA_permease PF00324.16 KPI35340.1 - 6.9e-112 374.2 41.0 8.2e-112 373.9 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI35340.1 - 4.9e-27 94.5 41.0 6e-27 94.2 28.4 1.1 1 0 0 1 1 1 1 Amino acid permease EF-hand_4 PF12763.2 KPI35341.1 - 6.7e-26 90.0 0.0 3.8e-13 49.0 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 KPI35341.1 - 6.2e-10 39.0 161.9 0.00023 21.1 28.3 7.3 4 2 2 6 6 6 4 Domain of unknown function (DUF1720) EF-hand_7 PF13499.1 KPI35341.1 - 7.5e-07 29.1 0.1 8.6e-05 22.5 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KPI35341.1 - 7.7e-05 21.7 0.0 0.0073 15.5 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KPI35341.1 - 0.012 15.1 0.0 0.035 13.7 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.1 KPI35341.1 - 0.013 15.2 0.0 0.67 9.9 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain EF-hand_9 PF14658.1 KPI35341.1 - 0.03 14.2 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain E3_binding PF02817.12 KPI35341.1 - 0.034 13.7 2.8 0.037 13.6 0.3 2.3 2 0 0 2 2 2 0 e3 binding domain AhpC-TSA PF00578.16 KPI35343.1 - 2.8e-16 59.3 0.0 3.8e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KPI35343.1 - 8e-09 35.1 0.0 1.2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KPI35343.1 - 0.00047 20.0 0.0 0.011 15.6 0.0 2.2 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.7 KPI35343.1 - 0.0044 16.4 0.0 0.0049 16.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Thioredoxin_2 PF13098.1 KPI35343.1 - 0.018 15.2 0.0 0.065 13.4 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KPI35343.1 - 0.019 15.0 0.0 0.056 13.5 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.1 KPI35343.1 - 0.028 13.9 0.0 4.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin Adeno_E3A PF05248.7 KPI35343.1 - 0.071 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3A Thioredoxin_7 PF13899.1 KPI35343.1 - 0.13 12.3 0.0 0.19 11.7 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like Zn_clus PF00172.13 KPI35344.1 - 3.9e-08 33.0 9.1 6.8e-08 32.2 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 KPI35345.1 - 1.6e-86 290.9 0.1 2.3e-86 290.3 0.0 1.2 1 0 0 1 1 1 1 Amidase FA_desaturase PF00487.19 KPI35346.1 - 8.1e-31 107.3 12.7 1.6e-30 106.4 8.8 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 KPI35346.1 - 1.2e-15 56.3 1.6 1.9e-15 55.7 0.2 2.0 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) DIOX_N PF14226.1 KPI35346.1 - 1.7e-15 57.5 0.0 3.5e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI35346.1 - 5.5e-15 55.4 0.0 1.5e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WSC PF01822.14 KPI35347.1 - 1.1e-79 262.3 91.0 1e-18 67.0 9.9 5.9 6 0 0 6 6 6 5 WSC domain Glyoxal_oxid_N PF07250.6 KPI35347.1 - 4.3e-22 78.3 1.4 2.2e-18 66.2 0.0 3.7 4 0 0 4 4 4 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KPI35347.1 - 1.3e-16 60.4 0.0 2.9e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Peptidase_M20 PF01546.23 KPI35348.1 - 2.3e-27 95.7 0.1 3e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KPI35348.1 - 2.1e-15 56.4 0.0 3.6e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF2254 PF10011.4 KPI35348.1 - 0.016 13.7 0.0 0.025 13.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) MS_channel PF00924.13 KPI35349.1 - 0.00089 18.6 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel Fungal_trans PF04082.13 KPI35351.1 - 3.2e-26 91.7 0.2 3e-19 68.9 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Glyco_hydro_16 PF00722.16 KPI35352.1 - 2.2e-19 69.4 1.1 4.5e-19 68.4 0.7 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 TPR_11 PF13414.1 KPI35353.1 - 0.0014 18.2 0.1 0.84 9.3 0.0 2.3 1 1 1 2 2 2 2 TPR repeat TPR_14 PF13428.1 KPI35353.1 - 0.18 12.5 1.1 76 4.3 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat NGP1NT PF08153.7 KPI35354.1 - 3e-47 159.7 1.0 4.7e-47 159.1 0.7 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KPI35354.1 - 1e-18 67.3 0.0 2.6e-14 53.1 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KPI35354.1 - 8.6e-05 21.8 0.0 0.0011 18.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 KPI35354.1 - 0.00023 20.4 0.1 0.052 12.7 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.18 KPI35354.1 - 0.0016 18.2 1.4 0.3 10.8 0.0 3.6 3 1 1 4 4 4 1 Dynamin family GTP_EFTU PF00009.22 KPI35354.1 - 0.0026 17.2 0.0 0.48 9.8 0.0 3.1 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KPI35354.1 - 0.0089 15.2 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SusD-like_3 PF14322.1 KPI35354.1 - 0.021 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Miro PF08477.8 KPI35354.1 - 0.11 13.0 0.1 19 5.7 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein DUF1720 PF08226.6 KPI35355.1 - 0.022 14.7 0.9 0.049 13.6 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1720) FAD_binding_3 PF01494.14 KPI35356.1 - 5.5e-12 45.4 0.1 1.3e-11 44.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KPI35356.1 - 0.00016 21.8 0.0 0.00035 20.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI35356.1 - 0.0066 16.4 0.1 0.015 15.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KPI35356.1 - 0.032 13.0 0.0 0.3 9.8 0.0 2.1 1 1 0 1 1 1 0 Squalene epoxidase Amino_oxidase PF01593.19 KPI35356.1 - 0.04 12.9 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KPI35356.1 - 0.11 12.8 0.2 0.49 10.8 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI35356.1 - 0.3 10.9 2.2 1 9.1 1.5 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MutS_V PF00488.16 KPI35358.1 - 4.5e-53 180.0 0.0 2.4e-52 177.6 0.0 2.0 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KPI35358.1 - 1.9e-22 80.0 0.5 3e-22 79.3 0.0 1.6 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 KPI35358.1 - 8e-05 22.7 0.0 0.00027 21.0 0.0 1.9 2 0 0 2 2 2 1 MutS family domain IV Aldolase_II PF00596.16 KPI35359.1 - 7e-42 143.1 0.3 1.1e-41 142.5 0.2 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Zn_clus PF00172.13 KPI35361.1 - 7.6e-09 35.3 9.1 1.3e-08 34.6 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCLP PF12304.3 KPI35361.1 - 0.05 13.0 0.4 0.087 12.2 0.3 1.3 1 0 0 1 1 1 0 Beta-casein like protein DUF1996 PF09362.5 KPI35362.1 - 3.8e-62 210.0 1.6 8.9e-62 208.8 1.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Amidase PF01425.16 KPI35363.1 - 3.3e-76 256.9 0.2 3.1e-75 253.7 0.1 2.1 1 1 0 1 1 1 1 Amidase p450 PF00067.17 KPI35364.1 - 5e-56 190.1 0.0 6.8e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 2-Hacid_dh_C PF02826.14 KPI35365.1 - 3e-36 124.2 0.4 1.1e-35 122.4 0.1 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KPI35365.1 - 2.3e-23 82.1 0.1 2.9e-23 81.7 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KPI35365.1 - 1.7e-10 40.9 1.2 6.8e-07 29.2 0.3 2.3 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KPI35365.1 - 6.7e-06 26.4 0.3 7.6e-05 23.0 0.0 2.6 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KPI35365.1 - 6.4e-05 22.6 0.0 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KPI35365.1 - 0.00081 18.9 0.3 0.059 12.9 0.1 2.5 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KPI35365.1 - 0.0012 18.8 1.1 0.057 13.4 0.1 2.7 2 1 0 2 2 2 1 TrkA-N domain ELFV_dehydrog PF00208.16 KPI35365.1 - 0.0013 18.3 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_Gly3P_dh_N PF01210.18 KPI35365.1 - 0.0037 16.9 0.3 0.013 15.2 0.1 2.1 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus XdhC_C PF13478.1 KPI35365.1 - 0.05 13.9 0.1 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.9 KPI35365.1 - 0.053 12.8 0.8 0.23 10.8 0.2 2.3 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.7 KPI35365.1 - 0.11 11.8 0.6 0.27 10.6 0.1 2.0 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Saccharop_dh PF03435.13 KPI35365.1 - 0.35 9.7 3.0 4.6 6.1 0.0 2.4 2 1 1 3 3 3 0 Saccharopine dehydrogenase Transp_cyt_pur PF02133.10 KPI35366.1 - 5.8e-105 351.3 39.8 6.7e-105 351.1 27.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SnoaL_2 PF12680.2 KPI35368.1 - 3.7e-06 27.2 0.0 4.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KPI35368.1 - 0.00019 21.5 0.0 0.00026 21.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 KPI35368.1 - 0.035 13.6 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase 2-Hacid_dh_C PF02826.14 KPI35369.1 - 3e-51 173.0 0.0 3.8e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KPI35369.1 - 5.2e-06 25.9 0.0 6.2e-06 25.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KPI35369.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_3 PF01494.14 KPI35370.1 - 1.8e-18 66.7 1.0 5.8e-18 65.0 0.7 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI35370.1 - 4.6e-10 38.9 3.2 3.8e-05 22.7 1.7 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KPI35370.1 - 1.8e-08 33.9 0.1 3.1e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KPI35370.1 - 4.2e-07 28.7 4.8 0.00027 19.5 2.7 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 KPI35370.1 - 1.1e-06 28.5 2.9 2.1e-06 27.6 1.4 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KPI35370.1 - 1.3e-06 28.7 2.7 0.00066 20.0 0.7 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI35370.1 - 5.2e-06 26.6 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI35370.1 - 4.8e-05 22.3 5.0 4.8e-05 22.3 3.5 2.2 2 1 0 3 3 3 1 FAD binding domain GIDA PF01134.17 KPI35370.1 - 5.3e-05 22.2 1.5 8.2e-05 21.6 1.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KPI35370.1 - 0.00011 22.1 2.2 0.00048 20.0 1.6 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KPI35370.1 - 0.00047 18.9 2.0 0.24 10.0 0.9 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Amino_oxidase PF01593.19 KPI35370.1 - 0.0032 16.5 3.0 0.71 8.8 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 KPI35370.1 - 0.0037 16.9 0.6 0.007 16.0 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KPI35370.1 - 0.0057 15.6 2.2 0.037 12.9 1.5 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein SE PF08491.5 KPI35370.1 - 0.0099 14.7 0.0 0.021 13.6 0.0 1.4 1 1 0 1 1 1 1 Squalene epoxidase Rossmann-like PF10727.4 KPI35370.1 - 0.12 12.0 0.3 6 6.6 0.0 2.4 2 0 0 2 2 2 0 Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 KPI35370.1 - 0.19 11.4 1.1 0.38 10.4 0.8 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short_C2 PF13561.1 KPI35371.1 - 1.3e-27 97.1 0.2 1.5e-27 96.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI35371.1 - 8.8e-25 87.5 0.8 1.3e-24 86.9 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI35371.1 - 2.7e-08 33.6 0.3 4.3e-08 33.0 0.2 1.3 1 0 0 1 1 1 1 KR domain DPRP PF04244.8 KPI35371.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein Methyltransf_26 PF13659.1 KPI35371.1 - 0.13 12.2 0.5 0.2 11.7 0.3 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KPI35372.1 - 1.8e-07 30.8 0.0 2.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI35372.1 - 2.5e-07 31.0 0.0 6e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI35372.1 - 7.8e-07 29.6 0.0 1.7e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI35372.1 - 2.4e-06 27.3 0.0 3.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI35372.1 - 4.8e-06 26.8 0.0 8.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI35372.1 - 4e-05 23.9 0.0 6.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KPI35372.1 - 0.00061 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 KPI35372.1 - 0.0008 18.5 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KPI35372.1 - 0.0011 18.9 0.0 0.0033 17.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KPI35372.1 - 0.0012 18.1 0.0 0.0021 17.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 KPI35372.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Adhesin_Dr PF04619.7 KPI35372.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Dr-family adhesin Lactamase_B PF00753.22 KPI35373.1 - 3.3e-07 30.1 0.5 5.6e-07 29.3 0.3 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI35373.1 - 0.0023 17.5 0.3 0.0035 16.8 0.2 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain F_bP_aldolase PF01116.15 KPI35374.1 - 1.5e-62 211.2 0.0 1.7e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II p450 PF00067.17 KPI35375.1 - 0.049 12.1 1.7 0.96 7.8 1.2 2.2 1 1 0 1 1 1 0 Cytochrome P450 EthD PF07110.6 KPI35376.1 - 5.4e-14 52.8 0.1 6.7e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 EthD domain Peptidase_M16_C PF05193.16 KPI35377.1 - 9.3e-32 110.1 0.1 4.1e-22 78.7 0.0 3.4 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KPI35377.1 - 8.4e-31 106.7 1.5 7.8e-30 103.5 1.2 2.5 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) ABA_WDS PF02496.11 KPI35379.1 - 0.0043 17.1 0.3 0.0043 17.1 0.2 9.0 8 1 0 8 8 8 2 ABA/WDS induced protein Borrelia_P83 PF05262.6 KPI35379.1 - 3.7 5.6 40.1 6.2 4.9 27.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein OmpH PF03938.9 KPI35379.1 - 7.9 6.4 28.2 20 5.0 19.6 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Cu-oxidase_3 PF07732.10 KPI35380.1 - 7e-39 132.2 4.9 9.5e-38 128.5 1.1 2.7 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 KPI35380.1 - 2.8e-26 92.3 0.1 7.6e-26 90.9 0.1 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KPI35380.1 - 1.9e-05 24.1 6.5 0.26 10.8 0.0 3.9 3 1 0 3 3 3 3 Multicopper oxidase Hap4_Hap_bind PF10297.4 KPI35381.1 - 6.2e-09 35.3 6.1 1.4e-08 34.2 4.2 1.6 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 KPI35381.1 - 1.1e-08 34.9 13.7 1.2e-05 25.1 4.9 2.3 1 1 1 2 2 2 2 bZIP transcription factor AAA_27 PF13514.1 KPI35381.1 - 0.0029 15.3 1.0 0.0039 14.9 0.7 1.1 1 0 0 1 1 1 1 AAA domain DUF2408 PF10303.4 KPI35381.1 - 0.014 15.4 0.1 0.023 14.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Filament PF00038.16 KPI35381.1 - 0.033 13.6 2.6 0.051 13.0 1.8 1.2 1 0 0 1 1 1 0 Intermediate filament protein IncA PF04156.9 KPI35381.1 - 0.058 12.9 0.6 0.1 12.1 0.4 1.4 1 0 0 1 1 1 0 IncA protein Phage_Mu_Gam PF07352.7 KPI35381.1 - 0.071 12.6 0.8 0.12 11.8 0.6 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein dsrm PF00035.20 KPI35381.1 - 0.078 13.5 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif Fmp27_WPPW PF10359.4 KPI35381.1 - 0.11 10.9 1.1 0.16 10.3 0.8 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain APG6 PF04111.7 KPI35381.1 - 0.36 9.8 1.8 0.52 9.3 1.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2051 PF09738.4 KPI35381.1 - 0.57 9.4 5.5 1.2 8.4 3.6 1.6 1 1 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) bZIP_2 PF07716.10 KPI35381.1 - 0.63 9.8 13.4 0.92 9.3 8.2 2.0 1 1 1 2 2 2 0 Basic region leucine zipper Jnk-SapK_ap_N PF09744.4 KPI35381.1 - 1.1 9.2 4.5 1.6 8.6 3.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 bZIP_Maf PF03131.12 KPI35381.1 - 1.6 9.0 9.1 7.7 6.8 6.3 2.0 1 1 0 1 1 1 0 bZIP Maf transcription factor HOOK PF05622.7 KPI35382.1 - 0.007 14.2 10.1 0.0099 13.7 7.0 1.1 1 0 0 1 1 1 1 HOOK protein Reo_sigmaC PF04582.7 KPI35382.1 - 0.012 14.7 0.8 0.018 14.2 0.5 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Exonuc_VII_L PF02601.10 KPI35382.1 - 0.022 13.9 7.1 0.044 12.9 4.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3813 PF12758.2 KPI35382.1 - 0.084 13.0 5.3 0.26 11.4 3.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) TMF_DNA_bd PF12329.3 KPI35382.1 - 0.26 11.1 12.0 0.18 11.6 2.6 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 KPI35382.1 - 0.3 10.6 16.2 0.076 12.5 1.6 3.9 2 1 2 4 4 4 0 Septum formation initiator Mnd1 PF03962.10 KPI35382.1 - 0.49 10.0 7.1 1 8.9 4.9 1.5 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 KPI35382.1 - 0.54 9.8 16.0 3.5 7.1 11.2 2.0 1 1 1 2 2 2 0 IncA protein Atg14 PF10186.4 KPI35382.1 - 0.58 9.0 7.5 1.3 7.9 5.2 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 KPI35382.1 - 0.67 10.3 7.0 0.81 10.0 1.0 3.0 1 1 1 2 2 2 0 SlyX Macoilin PF09726.4 KPI35382.1 - 0.9 7.7 11.7 1.8 6.7 8.1 1.4 2 0 0 2 2 2 0 Transmembrane protein Fib_alpha PF08702.5 KPI35382.1 - 1.5 8.9 5.6 3.8 7.6 3.9 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 KPI35382.1 - 2 6.2 4.9 2.9 5.6 3.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 KPI35382.1 - 3.9 6.3 9.9 6.9 5.5 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MCM PF00493.18 KPI35383.1 - 1.1e-128 428.7 0.0 1.7e-128 428.0 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KPI35383.1 - 1.3e-16 61.1 0.0 4.6e-16 59.3 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KPI35383.1 - 7.9e-07 28.4 0.0 1e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KPI35383.1 - 0.0097 15.5 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Transp_cyt_pur PF02133.10 KPI35386.1 - 2e-84 283.6 39.8 9.4e-84 281.4 27.6 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Abhydrolase_3 PF07859.8 KPI35387.1 - 2.3e-60 203.7 0.0 3.4e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KPI35387.1 - 5.4e-05 22.0 0.0 0.00012 20.9 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 KPI35387.1 - 0.0021 17.3 0.0 0.0068 15.6 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Viral_coat PF00729.13 KPI35387.1 - 0.0036 16.6 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 Viral coat protein (S domain) Abhydrolase_5 PF12695.2 KPI35387.1 - 0.0046 16.7 0.0 0.0063 16.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KPI35387.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Tim17 PF02466.14 KPI35388.1 - 1.1e-33 116.0 18.6 1.3e-32 112.5 12.9 2.1 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 KPI35388.1 - 0.15 12.0 0.0 0.15 12.0 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF543) Na_Ca_ex PF01699.19 KPI35389.1 - 2.1e-32 111.6 22.6 1.1e-19 70.4 5.4 3.5 5 0 0 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KPI35389.1 - 1.8e-13 50.6 12.2 1.8e-13 50.6 8.4 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF307) Pox_Ag35 PF03286.9 KPI35389.1 - 9 5.7 8.8 18 4.7 6.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MFS_1 PF07690.11 KPI35390.1 - 3e-19 68.9 35.5 3e-19 68.9 24.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily CorA PF01544.13 KPI35391.1 - 1.5e-09 37.3 1.5 2.3e-09 36.6 1.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein OPT PF03169.10 KPI35392.1 - 4.3e-199 662.9 40.8 5.3e-199 662.6 28.2 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Mito_carr PF00153.22 KPI35394.1 - 9.5e-63 207.9 0.8 4.3e-23 80.8 0.3 4.0 3 1 1 4 4 4 3 Mitochondrial carrier protein DUF1049 PF06305.6 KPI35394.1 - 0.0018 17.7 0.2 1.2 8.6 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1049) CRF PF00473.12 KPI35394.1 - 0.066 13.3 0.2 0.066 13.3 0.2 2.8 3 0 0 3 3 3 0 Corticotropin-releasing factor family RdRP PF05183.7 KPI35395.1 - 4.1e-166 554.0 0.0 1.9e-165 551.8 0.0 1.8 2 0 0 2 2 2 1 RNA dependent RNA polymerase RRM_1 PF00076.17 KPI35395.1 - 0.011 15.3 0.0 0.067 12.8 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2761 PF10959.3 KPI35395.1 - 0.055 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2761) Thymopoietin PF08198.6 KPI35395.1 - 0.066 12.7 0.0 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 Thymopoietin protein UCH PF00443.24 KPI35396.1 - 3.3e-51 173.9 0.0 7.4e-51 172.8 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KPI35396.1 - 1.2e-20 74.1 0.0 2e-14 53.7 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rrp15p PF07890.7 KPI35398.1 - 5.3e-34 117.0 8.9 5.3e-34 117.0 6.2 2.1 2 0 0 2 2 2 1 Rrp15p MARVEL PF01284.18 KPI35399.1 - 1.4e-05 24.9 10.5 2.3e-05 24.2 7.3 1.3 1 1 0 1 1 1 1 Membrane-associating domain DUF3311 PF11755.3 KPI35399.1 - 0.28 10.7 3.6 1.1 8.8 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) DUF998 PF06197.8 KPI35399.1 - 0.9 8.8 10.3 0.097 11.9 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF998) PhoD PF09423.5 KPI35401.1 - 1e-53 182.5 0.0 1.8e-53 181.7 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase MIP-T3 PF10243.4 KPI35402.1 - 6.2e-07 28.2 33.6 7.2e-07 28.0 23.3 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 PLRV_ORF5 PF01690.12 KPI35402.1 - 2.8 6.9 26.8 5 6.1 18.6 1.5 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF966 PF06136.8 KPI35402.1 - 4.1 6.7 23.6 6.2 6.1 16.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF572 PF04502.8 KPI35402.1 - 7.7 5.6 40.1 13 4.8 27.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) RNB PF00773.14 KPI35403.1 - 3.6e-84 282.8 0.0 7.7e-84 281.7 0.0 1.6 1 0 0 1 1 1 1 RNB domain DUF4239 PF14023.1 KPI35403.1 - 0.028 13.7 0.1 0.066 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) EF1_GNE PF00736.14 KPI35404.1 - 6.6e-30 102.6 4.3 3.8e-29 100.2 3.1 2.1 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain eIF-5_eIF-2B PF01873.12 KPI35404.1 - 1.9e-09 37.2 0.8 1.4e-06 27.9 0.5 2.5 1 1 0 1 1 1 1 Domain found in IF2B/IF5 Ribosomal_S27e PF01667.12 KPI35404.1 - 0.0029 17.1 2.6 0.0058 16.1 1.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S27 HET PF06985.6 KPI35405.1 - 5.3e-15 55.8 0.0 1e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fer2 PF00111.22 KPI35406.1 - 4.1e-14 52.0 1.1 5.9e-14 51.5 0.8 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Hemerythrin PF01814.18 KPI35407.1 - 1.2e-08 35.1 2.3 1.7e-08 34.6 1.6 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain F_actin_bind PF08919.5 KPI35407.1 - 0.14 11.8 0.1 0.38 10.4 0.0 1.6 2 0 0 2 2 2 0 F-actin binding Pyridox_oxidase PF01243.15 KPI35408.1 - 3.6e-05 23.7 0.0 6.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Glyco_transf_90 PF05686.7 KPI35410.1 - 3e-15 55.8 6.4 6.2e-13 48.1 3.0 3.4 2 1 0 2 2 2 2 Glycosyl transferase family 90 DASH_Spc34 PF08657.5 KPI35412.1 - 0.0034 17.0 2.8 0.0034 17.0 1.9 2.2 1 1 1 2 2 2 1 DASH complex subunit Spc34 AAA_13 PF13166.1 KPI35412.1 - 0.0037 15.8 3.1 0.0052 15.3 2.1 1.2 1 0 0 1 1 1 1 AAA domain Lipase_chap PF03280.9 KPI35412.1 - 0.0038 16.7 3.7 0.0038 16.7 2.6 2.6 2 1 0 3 3 3 1 Proteobacterial lipase chaperone protein Reo_sigmaC PF04582.7 KPI35412.1 - 0.0065 15.7 0.9 0.0065 15.7 0.6 2.0 2 0 0 2 2 2 1 Reovirus sigma C capsid protein LPP PF04728.8 KPI35412.1 - 0.0081 15.9 2.2 0.042 13.6 0.0 2.7 2 0 0 2 2 2 1 Lipoprotein leucine-zipper Ly49 PF08391.5 KPI35412.1 - 0.015 15.4 0.6 0.051 13.6 0.0 2.1 3 0 0 3 3 1 0 Ly49-like protein, N-terminal region DUF3584 PF12128.3 KPI35412.1 - 0.019 12.3 8.9 0.034 11.5 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 KPI35412.1 - 0.025 14.1 16.7 0.84 9.1 6.2 2.4 1 1 0 2 2 2 0 IncA protein Med9 PF07544.8 KPI35412.1 - 0.041 13.6 0.6 0.041 13.6 0.4 3.7 2 2 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Katanin_con80 PF13925.1 KPI35412.1 - 0.074 12.7 0.5 0.73 9.5 0.0 2.4 2 0 0 2 2 2 0 con80 domain of Katanin COG5 PF10392.4 KPI35412.1 - 0.078 12.9 9.8 3.2 7.7 0.1 3.6 2 1 2 4 4 4 0 Golgi transport complex subunit 5 ERM PF00769.14 KPI35412.1 - 0.093 12.2 16.9 0.07 12.6 7.2 2.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DivIC PF04977.10 KPI35412.1 - 0.11 11.9 18.6 0.11 12.0 4.9 3.4 3 0 0 3 3 3 0 Septum formation initiator HAP1_N PF04849.8 KPI35412.1 - 0.12 11.2 7.3 0.36 9.7 0.2 2.3 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Streptin-Immun PF11083.3 KPI35412.1 - 0.17 11.9 4.6 1.8 8.6 0.2 3.5 3 1 1 4 4 4 0 Lantibiotic streptin immunity protein DUF1192 PF06698.6 KPI35412.1 - 0.19 11.5 0.1 0.19 11.5 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) Tropomyosin_1 PF12718.2 KPI35412.1 - 0.27 11.0 18.6 65 3.3 12.9 2.9 1 1 0 1 1 1 0 Tropomyosin like HALZ PF02183.13 KPI35412.1 - 0.34 10.6 0.1 0.34 10.6 0.1 3.3 4 0 0 4 4 3 0 Homeobox associated leucine zipper ATG16 PF08614.6 KPI35412.1 - 0.4 10.4 19.5 0.039 13.7 6.8 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4201 PF13870.1 KPI35412.1 - 0.41 10.0 10.0 0.26 10.7 3.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) SlyX PF04102.7 KPI35412.1 - 0.57 10.5 12.1 8.1 6.9 0.1 4.3 3 1 0 3 3 3 0 SlyX Fib_alpha PF08702.5 KPI35412.1 - 0.82 9.7 4.1 0.95 9.5 0.9 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 KPI35412.1 - 1 9.1 4.1 2.9 7.7 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.6 KPI35412.1 - 1.3 8.9 10.5 4.9 7.0 1.6 3.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4482 PF14818.1 KPI35412.1 - 1.4 9.5 9.4 0.3 11.7 0.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) HOOK PF05622.7 KPI35412.1 - 1.6 6.4 13.5 5.1 4.7 9.4 1.7 1 1 0 1 1 1 0 HOOK protein TMF_DNA_bd PF12329.3 KPI35412.1 - 1.7 8.5 16.6 1.4 8.7 2.0 3.7 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding GAS PF13851.1 KPI35412.1 - 1.8 7.7 17.0 0.41 9.7 2.5 3.1 1 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.4 KPI35412.1 - 2 8.6 9.8 6.8 6.8 0.0 4.0 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3138 PF11336.3 KPI35412.1 - 2 6.5 10.7 0.055 11.6 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Atg14 PF10186.4 KPI35412.1 - 2.4 7.0 18.3 1.1 8.0 1.5 2.5 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF869 PF05911.6 KPI35412.1 - 2.5 6.2 14.2 0.12 10.5 3.0 2.1 1 1 0 2 2 2 0 Plant protein of unknown function (DUF869) Mnd1 PF03962.10 KPI35412.1 - 2.5 7.7 16.0 1.2 8.7 1.3 2.5 1 1 1 2 2 2 0 Mnd1 family CENP-F_leu_zip PF10473.4 KPI35412.1 - 3.2 7.5 18.7 2.1 8.2 3.5 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.11 KPI35412.1 - 4.6 7.3 18.0 2.5 8.1 8.1 3.0 1 1 1 2 2 2 0 Flagellar FliJ protein CENP-H PF05837.7 KPI35412.1 - 4.7 7.4 7.8 1.7 8.8 0.4 2.8 3 0 0 3 3 3 0 Centromere protein H (CENP-H) APG6 PF04111.7 KPI35412.1 - 4.8 6.1 15.8 1.8 7.5 7.6 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF972 PF06156.8 KPI35412.1 - 5.6 7.3 14.2 3.3 8.0 1.2 3.5 2 1 1 4 4 3 0 Protein of unknown function (DUF972) DUF4094 PF13334.1 KPI35412.1 - 7.7 6.9 6.7 3.5 8.0 0.3 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) CTNNBL PF08216.6 KPI35413.1 - 6.9e-24 83.5 0.5 2.4e-23 81.7 0.2 2.0 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 KPI35413.1 - 0.022 14.5 0.1 7.8 6.4 0.0 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF3570 PF12094.3 KPI35414.1 - 0.013 14.2 0.2 0.018 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) TEBP_beta PF07404.6 KPI35414.1 - 1 8.4 3.3 2.1 7.3 2.2 1.6 2 0 0 2 2 2 0 Telomere-binding protein beta subunit (TEBP beta) Reo_sigmaC PF04582.7 KPI35415.1 - 0.0021 17.3 8.1 0.0021 17.3 5.6 2.6 1 1 0 2 2 2 1 Reovirus sigma C capsid protein F-box PF00646.28 KPI35416.1 - 0.0034 17.0 0.0 0.013 15.1 0.0 2.0 1 0 0 1 1 1 1 F-box domain RRM_1 PF00076.17 KPI35417.1 - 2.3e-05 23.9 0.0 4.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI35417.1 - 0.0002 21.2 0.0 0.00046 20.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI35417.1 - 0.028 14.2 0.0 0.075 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S4 PF00163.14 KPI35418.1 - 3.1e-30 104.4 1.4 5.4e-30 103.6 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KPI35418.1 - 4.8e-13 48.3 1.0 4.8e-13 48.3 0.7 2.6 3 0 0 3 3 3 1 S4 domain MutS_V PF00488.16 KPI35419.1 - 2.3e-84 282.4 0.0 4.1e-84 281.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KPI35419.1 - 2e-38 132.2 7.1 2e-38 132.2 4.9 3.2 3 0 0 3 3 3 1 MutS domain III MutS_I PF01624.15 KPI35419.1 - 2.5e-21 75.8 0.0 5.4e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KPI35419.1 - 2.4e-10 40.6 0.2 7.5e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 MutS domain II AAA_29 PF13555.1 KPI35419.1 - 0.0076 15.7 0.0 0.03 13.8 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain YmaF PF12788.2 KPI35419.1 - 0.14 12.2 1.8 0.21 11.7 0.1 2.2 2 0 0 2 2 2 0 YmaF family AAA_23 PF13476.1 KPI35419.1 - 1.7 8.9 0.0 1.7 8.9 0.0 2.7 3 1 0 3 3 3 0 AAA domain MFS_1 PF07690.11 KPI35420.1 - 3.8e-37 127.8 23.4 3.8e-37 127.8 16.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3188 PF11384.3 KPI35420.1 - 0.02 14.4 0.1 0.81 9.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Fungal_trans PF04082.13 KPI35421.1 - 2.7e-43 147.7 1.6 3.7e-43 147.2 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PGI PF00342.14 KPI35422.1 - 6.5e-206 684.4 3.8 1.8e-205 682.9 2.6 1.6 1 1 0 1 1 1 1 Phosphoglucose isomerase YppG PF14179.1 KPI35422.1 - 0.12 12.9 0.1 0.33 11.5 0.0 1.7 1 0 0 1 1 1 0 YppG-like protein RNA_pol_Rpb2_1 PF04563.10 KPI35423.1 - 2e-36 124.8 0.0 4.8e-36 123.6 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KPI35423.1 - 5.5e-33 113.9 0.0 1.1e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KPI35423.1 - 1.3e-22 79.3 0.0 2.5e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KPI35423.1 - 8.9e-19 67.1 0.2 2e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.8 KPI35423.1 - 3.5e-17 61.9 1.0 7e-17 60.9 0.7 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 MFS_1 PF07690.11 KPI35424.1 - 1.9e-42 145.2 38.3 4.6e-38 130.8 14.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI35424.1 - 2.9e-08 32.7 6.4 2.9e-08 32.7 4.4 2.3 2 2 2 4 4 4 1 Sugar (and other) transporter BTB PF00651.26 KPI35424.1 - 1.2e-06 28.4 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain LacY_symp PF01306.14 KPI35424.1 - 0.0067 15.0 0.9 0.0067 15.0 0.7 1.9 2 0 0 2 2 2 1 LacY proton/sugar symporter NMO PF03060.10 KPI35425.1 - 6.5e-66 222.7 5.9 1.4e-65 221.6 4.1 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KPI35425.1 - 2.4e-07 29.9 3.1 2.9e-06 26.4 2.2 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KPI35425.1 - 2.3e-05 23.3 0.9 5.1e-05 22.2 0.6 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KPI35425.1 - 0.0057 15.6 1.9 0.0077 15.1 0.5 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase DHO_dh PF01180.16 KPI35425.1 - 0.031 13.2 0.6 0.059 12.3 0.1 1.7 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase p450 PF00067.17 KPI35426.1 - 4.2e-47 160.7 0.0 7.2e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NADH_u_ox_C PF12853.2 KPI35426.1 - 3.1e-32 110.1 0.1 6.5e-32 109.1 0.1 1.5 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 KPI35426.1 - 1.3e-19 70.1 0.2 3.6e-19 68.7 0.2 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit COesterase PF00135.23 KPI35427.1 - 3.6e-92 309.8 0.0 4.7e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI35427.1 - 3.1e-05 23.6 0.0 0.00012 21.7 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI35427.1 - 0.00053 19.2 0.0 0.00089 18.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family RNB PF00773.14 KPI35428.1 - 4e-34 118.3 0.0 2e-33 116.0 0.0 1.9 1 1 0 1 1 1 1 RNB domain PRKCSH-like PF12999.2 KPI35429.1 - 2.8e-49 167.0 3.8 2.5e-27 95.5 0.7 2.5 2 0 0 2 2 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 KPI35429.1 - 6.3e-32 110.1 0.4 1.4e-31 109.0 0.3 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KPI35429.1 - 9.9e-12 45.5 0.5 3e-11 43.9 0.3 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein MAD PF05557.8 KPI35429.1 - 0.015 13.4 6.3 0.025 12.7 4.4 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF4407 PF14362.1 KPI35429.1 - 0.25 10.2 10.1 1.4 7.8 4.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Smac_DIABLO PF09057.5 KPI35429.1 - 0.35 9.9 4.8 0.074 12.1 0.6 1.8 2 0 0 2 2 2 0 Second Mitochondria-derived Activator of Caspases DUF1664 PF07889.7 KPI35429.1 - 0.74 9.6 11.8 8.9 6.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Filament PF00038.16 KPI35429.1 - 1.2 8.4 11.9 4.7 6.5 3.6 2.7 3 0 0 3 3 3 0 Intermediate filament protein FliT PF05400.8 KPI35429.1 - 1.8 8.9 8.0 24 5.4 0.1 2.6 2 0 0 2 2 2 0 Flagellar protein FliT Ribosomal_L21e PF01157.13 KPI35430.1 - 1.4e-38 130.6 7.0 1.7e-38 130.4 4.3 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e AAA_33 PF13671.1 KPI35432.1 - 4.7e-13 49.2 0.5 1.1e-12 48.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KPI35432.1 - 8.9e-10 37.9 0.0 1.7e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 KPI35432.1 - 2.7e-07 31.4 0.7 2.2e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KPI35432.1 - 0.0029 17.9 3.5 0.0034 17.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 KPI35432.1 - 0.0033 16.6 3.4 0.019 14.2 0.0 2.5 2 1 1 3 3 3 1 Chromatin associated protein KTI12 Not3 PF04065.10 KPI35432.1 - 0.01 15.1 4.1 0.023 13.9 2.7 1.7 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component AAA_16 PF13191.1 KPI35432.1 - 0.019 14.9 0.5 0.17 11.8 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain APS_kinase PF01583.15 KPI35432.1 - 0.035 13.7 2.1 0.41 10.2 0.0 3.0 2 2 0 3 3 3 0 Adenylylsulphate kinase Toxin_52 PF15605.1 KPI35432.1 - 0.045 13.6 1.4 3.4 7.6 0.1 2.6 2 0 0 2 2 2 0 Putative toxin 52 ABC_tran PF00005.22 KPI35432.1 - 0.16 12.2 0.4 1 9.6 0.0 2.3 2 1 0 2 2 2 0 ABC transporter CTNNBL PF08216.6 KPI35432.1 - 3.7 7.1 7.4 0.64 9.6 1.4 2.4 3 0 0 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear Swi3 PF07962.7 KPI35433.1 - 2.8e-28 97.3 0.1 5.8e-28 96.3 0.1 1.6 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 SSFA2_C PF14723.1 KPI35434.1 - 0.13 11.9 2.0 4.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus Pterin_bind PF00809.17 KPI35436.1 - 5.8e-70 234.9 0.0 1.6e-69 233.4 0.0 1.7 2 0 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 KPI35436.1 - 1e-35 122.2 0.0 1.7e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Polyketide_cyc2 PF10604.4 KPI35439.1 - 1.4e-05 25.2 0.3 0.00012 22.2 0.0 2.1 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 KPI35439.1 - 0.0028 17.6 0.0 0.0049 16.8 0.0 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Glyco_transf_15 PF01793.11 KPI35440.1 - 2.3e-114 381.8 15.1 1.7e-113 378.9 10.5 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_hydro_18 PF00704.23 KPI35441.1 - 8.9e-10 38.5 0.0 1.3e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 MFS_1 PF07690.11 KPI35442.1 - 2.5e-36 125.1 27.2 2.5e-36 125.1 18.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily SBDS_C PF09377.5 KPI35443.1 - 3.3e-44 149.5 0.0 4.5e-44 149.1 0.0 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 KPI35443.1 - 2.9e-23 81.4 0.0 6.4e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Mito_carr PF00153.22 KPI35444.1 - 2.6e-14 52.6 3.9 0.0068 16.0 0.1 5.4 4 1 0 4 4 4 4 Mitochondrial carrier protein Peptidase_C15 PF01470.12 KPI35445.1 - 5.2e-10 39.4 0.0 7.3e-07 29.2 0.0 3.2 2 1 0 2 2 2 2 Pyroglutamyl peptidase Mtc PF03820.12 KPI35446.1 - 1.1e-106 356.0 0.2 2.1e-106 355.0 0.2 1.4 1 1 0 1 1 1 1 Tricarboxylate carrier RNA_pol_Rpb2_6 PF00562.23 KPI35448.1 - 2.2e-111 372.3 0.6 2.7e-111 372.0 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.15 KPI35448.1 - 9.1e-31 105.9 0.0 1.6e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Citrate_ly_lig PF08218.6 KPI35448.1 - 0.054 12.9 0.1 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Citrate lyase ligase C-terminal domain MFS_1 PF07690.11 KPI35449.1 - 1.9e-09 36.7 18.0 1.9e-09 36.7 12.5 2.2 1 1 2 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI35449.1 - 0.002 16.7 0.5 0.002 16.7 0.3 3.0 4 0 0 4 4 4 2 Sugar (and other) transporter ESSS PF10183.4 KPI35449.1 - 0.12 12.7 0.3 0.47 10.8 0.2 2.1 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PAE PF03283.8 KPI35449.1 - 0.23 10.0 0.0 0.35 9.4 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase DUF788 PF05620.6 KPI35449.1 - 0.31 10.8 1.6 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF788) Opi1 PF08618.5 KPI35450.1 - 2e-61 208.2 0.0 2.1e-45 155.4 0.0 3.5 1 1 2 3 3 3 3 Transcription factor Opi1 Pex14_N PF04695.8 KPI35450.1 - 0.18 11.8 7.4 1.6 8.7 1.2 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SRP54 PF00448.17 KPI35451.1 - 1.8e-72 242.9 1.4 1.8e-72 242.9 1.0 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KPI35451.1 - 2.9e-26 91.7 5.2 2.9e-26 91.7 3.6 3.8 2 1 1 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.14 KPI35451.1 - 5.9e-12 45.5 0.1 2.3e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KPI35451.1 - 3.8e-08 32.9 0.5 1.2e-07 31.3 0.1 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KPI35451.1 - 1e-06 28.7 0.0 2.3e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KPI35451.1 - 7.9e-06 25.6 0.9 5.9e-05 22.8 0.1 2.7 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KPI35451.1 - 1.2e-05 26.1 0.0 3.5e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_31 PF13614.1 KPI35451.1 - 0.00025 20.9 0.0 0.088 12.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain CbiA PF01656.18 KPI35451.1 - 0.00044 19.7 0.5 0.0019 17.6 0.3 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.15 KPI35451.1 - 0.00073 19.2 0.1 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 KPI35451.1 - 0.001 18.2 0.0 0.002 17.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 KPI35451.1 - 0.0029 17.7 0.2 0.011 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain 6PF2K PF01591.13 KPI35451.1 - 0.0033 16.5 0.0 0.0085 15.1 0.0 1.7 1 0 0 1 1 1 1 6-phosphofructo-2-kinase SRPRB PF09439.5 KPI35451.1 - 0.0036 16.5 1.4 1.2 8.3 0.6 3.3 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.12 KPI35451.1 - 0.0044 16.4 0.7 0.024 14.0 0.0 2.4 2 0 0 2 2 2 1 Thymidylate kinase AAA_18 PF13238.1 KPI35451.1 - 0.0049 17.1 0.0 0.017 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KPI35451.1 - 0.0068 16.4 0.0 0.015 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 KPI35451.1 - 0.01 15.7 0.1 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KPI35451.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain ATP_bind_1 PF03029.12 KPI35451.1 - 0.019 14.5 1.0 0.049 13.1 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 KPI35451.1 - 0.029 13.7 0.0 0.058 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KPI35451.1 - 0.039 13.7 0.8 0.25 11.1 0.0 2.7 4 0 0 4 4 4 0 Part of AAA domain VirE PF05272.6 KPI35451.1 - 0.044 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Virulence-associated protein E Arf PF00025.16 KPI35451.1 - 0.048 12.8 0.5 0.2 10.9 0.0 2.2 2 1 0 2 2 2 0 ADP-ribosylation factor family Arv1 PF04161.8 KPI35452.1 - 5e-17 62.4 0.0 1e-16 61.5 0.0 1.4 2 0 0 2 2 2 1 Arv1-like family GFA PF04828.9 KPI35453.1 - 1.8e-15 56.6 0.2 1.8e-15 56.6 0.1 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme TauD PF02668.11 KPI35455.1 - 4.6e-49 167.4 0.1 5.7e-49 167.1 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SGL PF08450.7 KPI35456.1 - 2.7e-59 200.5 0.0 3.5e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KPI35456.1 - 0.0087 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Arylesterase DUF839 PF05787.8 KPI35456.1 - 0.028 13.3 0.0 0.16 10.8 0.0 2.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF839) NHL PF01436.16 KPI35456.1 - 0.048 13.6 0.0 0.33 10.9 0.0 2.4 2 0 0 2 2 2 0 NHL repeat PD40 PF07676.7 KPI35456.1 - 0.1 12.2 0.5 0.54 9.9 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Reg_prop PF07494.6 KPI35456.1 - 0.13 12.3 0.3 10 6.5 0.0 3.6 3 0 0 3 3 3 0 Two component regulator propeller Voldacs PF03517.8 KPI35457.1 - 8.1e-28 96.9 0.0 8.1e-28 96.9 0.0 2.5 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling DUF3992 PF13157.1 KPI35458.1 - 0.028 14.6 5.0 0.27 11.4 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3992) Herpes_BLLF1 PF05109.8 KPI35458.1 - 2 6.3 22.0 2.4 5.9 15.2 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) PSD5 PF07637.6 KPI35459.1 - 0.73 9.9 2.9 20 5.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1595) RNase_T PF00929.19 KPI35460.1 - 8.1e-18 65.2 0.2 8.1e-18 65.2 0.2 1.8 2 0 0 2 2 2 1 Exonuclease Peptidase_S31 PF05578.7 KPI35460.1 - 0.04 13.1 0.2 0.079 12.1 0.2 1.4 1 0 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 MFS_1 PF07690.11 KPI35462.1 - 1e-17 63.8 48.5 8e-17 60.9 13.1 2.5 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KPI35462.1 - 1.1e-05 23.8 2.7 1.1e-05 23.8 1.9 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_2 PF00891.13 KPI35463.1 - 5.2e-26 91.3 0.0 6.8e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_PK PF05891.7 KPI35463.1 - 0.056 12.7 0.0 0.095 11.9 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase SIR2 PF02146.12 KPI35464.1 - 3.7e-26 91.9 0.0 1.5e-25 89.9 0.0 1.9 1 1 0 1 1 1 1 Sir2 family SelB-wing_2 PF09106.6 KPI35464.1 - 0.014 15.2 0.6 2.3 8.1 0.3 2.7 2 0 0 2 2 2 0 Elongation factor SelB, winged helix GFA PF04828.9 KPI35465.1 - 4e-20 71.5 0.1 7e-20 70.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DIM1 PF02966.11 KPI35466.1 - 2.1e-70 234.3 0.6 2.4e-70 234.2 0.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 KPI35466.1 - 0.0011 19.0 0.6 0.0019 18.2 0.4 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 KPI35466.1 - 0.0018 17.9 0.1 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin PIF1 PF05970.9 KPI35467.1 - 9.9e-59 199.0 2.2 1.4e-44 152.5 0.1 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KPI35467.1 - 1.1e-17 64.3 0.0 1.9e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KPI35467.1 - 2.9e-07 30.6 0.0 6.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 KPI35467.1 - 1.3e-05 25.2 0.2 0.00039 20.5 0.1 2.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 KPI35467.1 - 3.7e-05 21.7 0.1 0.00059 17.7 0.0 2.1 2 0 0 2 2 2 1 Helicase AAA PF00004.24 KPI35467.1 - 0.0036 17.5 0.0 0.0086 16.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KPI35467.1 - 0.0038 16.4 0.2 0.015 14.5 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.1 KPI35467.1 - 0.0081 16.1 0.1 0.026 14.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 KPI35467.1 - 0.012 15.3 0.1 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 KPI35467.1 - 0.014 15.5 0.0 0.055 13.6 0.0 2.1 1 1 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.4 KPI35467.1 - 0.035 12.7 0.1 0.061 11.9 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 KPI35467.1 - 0.039 12.9 0.0 0.039 12.9 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) EF-1_beta_acid PF10587.4 KPI35467.1 - 0.051 13.7 0.5 0.051 13.7 0.3 2.5 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region AAA_25 PF13481.1 KPI35467.1 - 0.053 12.9 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KPI35467.1 - 0.061 12.7 0.7 0.75 9.1 0.3 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 KPI35467.1 - 0.072 12.6 0.1 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.24 KPI35467.1 - 0.082 12.4 1.1 0.86 9.0 0.2 2.5 2 1 1 3 3 3 0 DEAD/DEAH box helicase ABC_tran PF00005.22 KPI35467.1 - 0.11 12.8 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 KPI35467.1 - 0.12 12.2 0.0 0.48 10.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KPI35467.1 - 0.12 12.0 0.3 1.2 8.8 0.2 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MFS_1 PF07690.11 KPI35468.1 - 1.3e-36 126.0 50.7 1.3e-36 126.0 35.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KPI35468.1 - 2e-13 49.4 29.2 2e-13 49.4 20.3 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.23 KPI35469.1 - 1.7e-69 234.2 0.1 2.2e-69 233.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI35469.1 - 3e-11 44.1 0.0 6.7e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hemerythrin PF01814.18 KPI35470.1 - 1.6e-10 41.2 1.7 2.1e-10 40.8 1.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain ACDC PF14733.1 KPI35470.1 - 0.16 12.1 0.1 0.45 10.6 0.1 1.7 1 0 0 1 1 1 0 AP2-coincident C-terminal MFS_1 PF07690.11 KPI35471.1 - 1e-50 172.4 28.4 1e-50 172.4 19.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI35471.1 - 3.4e-12 45.6 23.3 1.5e-11 43.6 16.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KPI35471.1 - 9.2e-06 24.1 2.1 1.4e-05 23.4 1.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2269 PF10027.4 KPI35471.1 - 0.011 15.5 8.3 2 8.1 3.4 3.3 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2269) NAD_kinase PF01513.16 KPI35472.1 - 5.6e-72 241.9 0.0 8.7e-72 241.2 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Peptidase_M16_C PF05193.16 KPI35473.1 - 5.7e-54 182.5 0.0 9.5e-53 178.6 0.0 2.4 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KPI35473.1 - 1.7e-39 134.9 0.0 3.6e-39 133.8 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Voltage_CLC PF00654.15 KPI35474.1 - 5.8e-88 295.2 26.7 8.2e-88 294.8 18.5 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 KPI35474.1 - 4.7e-12 45.4 0.0 7.4e-06 25.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain SPC25 PF06703.6 KPI35474.1 - 0.68 9.5 2.9 12 5.4 0.0 2.6 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Peptidase_S26 PF10502.4 KPI35475.1 - 1.6e-06 27.6 0.0 2.8e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Tfb4 PF03850.9 KPI35476.1 - 1.8e-85 286.5 2.3 1.4e-82 277.0 1.6 2.7 1 1 0 1 1 1 1 Transcription factor Tfb4 Phage_holin_1 PF04531.8 KPI35476.1 - 0.11 12.5 1.0 0.97 9.5 0.0 2.6 3 0 0 3 3 3 0 Bacteriophage holin RRM_1 PF00076.17 KPI35477.1 - 5.1e-57 189.4 0.0 1.9e-20 72.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI35477.1 - 6.8e-43 144.5 0.0 7.1e-14 51.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI35477.1 - 6.6e-31 105.9 0.0 1.6e-11 43.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KPI35477.1 - 3.4e-06 26.7 0.1 0.016 14.9 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KPI35477.1 - 0.0017 18.1 0.1 0.31 10.9 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif Cas_Cas2CT1978 PF09707.5 KPI35477.1 - 0.0025 17.7 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RNA_bind PF08675.6 KPI35477.1 - 0.083 12.8 0.0 4.7 7.2 0.0 2.4 2 0 0 2 2 2 0 RNA binding domain Abhydrolase_6 PF12697.2 KPI35478.1 - 2.2e-20 73.5 0.1 2.9e-20 73.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI35478.1 - 5.7e-13 48.8 0.0 8.8e-13 48.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family TIP_N PF12457.3 KPI35479.1 - 0.021 14.9 0.4 0.026 14.5 0.3 1.2 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal DUF4502 PF14950.1 KPI35480.1 - 0.072 12.2 0.4 0.082 12.0 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) Sporozoite_P67 PF05642.6 KPI35480.1 - 1.1 6.9 6.2 1.3 6.7 4.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen adh_short PF00106.20 KPI35481.1 - 5.7e-10 39.3 0.0 3.7e-09 36.7 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI35481.1 - 1.6e-07 31.1 0.0 4.3e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI35481.1 - 0.00019 20.9 0.0 0.00044 19.7 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Pribosyltran PF00156.22 KPI35482.1 - 8e-07 28.8 0.2 2.8e-06 27.0 0.1 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DSPc PF00782.15 KPI35483.1 - 4.1e-05 23.1 0.0 8.8e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain tRNA_U5-meth_tr PF05958.6 KPI35484.1 - 2.5e-10 39.5 0.0 1.4e-07 30.5 0.0 3.2 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_26 PF13659.1 KPI35484.1 - 1e-06 28.7 0.0 1.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 KPI35484.1 - 2e-06 27.5 0.0 4.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 TRAM domain PrmA PF06325.8 KPI35484.1 - 3.9e-06 26.1 0.0 6.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KPI35484.1 - 1.4e-05 24.7 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KPI35484.1 - 5.5e-05 22.7 0.0 8.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 KPI35484.1 - 0.003 18.1 0.0 0.0063 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KPI35484.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein MTS PF05175.9 KPI35484.1 - 0.026 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain UPF0020 PF01170.13 KPI35484.1 - 0.029 13.9 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 HA2 PF04408.18 KPI35485.1 - 5.3e-28 97.0 0.1 5.3e-28 97.0 0.1 2.2 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KPI35485.1 - 4.2e-25 87.7 0.0 9.4e-25 86.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KPI35485.1 - 2.5e-12 46.4 0.0 6.9e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 KPI35485.1 - 1.4e-09 37.8 1.9 2.8e-09 36.9 1.3 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 KPI35485.1 - 2.9e-07 30.1 0.1 6.5e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KPI35485.1 - 0.00014 22.0 0.0 0.00037 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KPI35485.1 - 0.00033 19.6 0.0 0.00098 18.0 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 KPI35485.1 - 0.0023 17.5 0.1 0.01 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KPI35485.1 - 0.0039 16.8 0.1 0.014 15.1 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KPI35485.1 - 0.086 12.7 0.2 0.81 9.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KPI35485.1 - 0.22 11.8 1.8 0.93 9.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KPI35485.1 - 0.75 10.0 4.3 1.6 9.0 0.2 3.2 2 1 0 2 2 2 0 ABC transporter GMP_synt_C PF00958.17 KPI35486.1 - 5e-37 125.5 0.0 1e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 KPI35486.1 - 1.1e-36 126.1 0.0 2e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 KPI35486.1 - 2.6e-10 39.6 0.1 3.6e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 KPI35486.1 - 4.6e-08 32.7 0.0 8.1e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.8 KPI35486.1 - 0.0055 16.0 0.0 0.041 13.1 0.0 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 KPI35486.1 - 0.0059 15.2 0.1 0.011 14.3 0.0 1.4 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.16 KPI35486.1 - 0.0062 16.0 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 KPI35486.1 - 0.0074 15.7 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 KPI35486.1 - 0.044 13.6 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.14 KPI35486.1 - 0.066 12.2 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.15 KPI35486.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family TauD PF02668.11 KPI35487.1 - 1.7e-23 83.5 0.0 2.4e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family EamA PF00892.15 KPI35488.1 - 1.7e-05 24.8 11.5 2.3e-05 24.4 7.9 1.2 1 0 0 1 1 1 1 EamA-like transporter family UPF0546 PF10639.4 KPI35488.1 - 0.00047 19.9 2.1 0.00055 19.7 1.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 EmrE PF13536.1 KPI35488.1 - 0.004 17.3 3.6 0.004 17.3 2.5 2.0 1 1 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 KPI35488.1 - 0.28 10.8 9.4 0.29 10.7 3.1 2.1 1 1 1 2 2 2 0 Triose-phosphate Transporter family HET PF06985.6 KPI35489.1 - 2.8e-29 102.0 2.1 5.7e-29 101.0 1.4 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nipped-B_C PF12830.2 KPI35490.1 - 5e-30 104.5 1.0 4.1e-28 98.2 0.0 3.7 4 0 0 4 4 4 1 Sister chromatid cohesion C-terminus Adaptin_N PF01602.15 KPI35490.1 - 0.00012 20.5 0.1 0.0045 15.3 0.1 2.8 2 1 1 3 3 3 2 Adaptin N terminal region Cohesin_HEAT PF12765.2 KPI35490.1 - 0.0007 19.5 4.8 0.0015 18.4 1.9 2.9 2 1 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 KPI35490.1 - 0.021 14.8 4.5 9.5 6.6 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat Vps16_N PF04841.8 KPI35492.1 - 2e-99 332.9 0.0 2.8e-99 332.4 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 KPI35492.1 - 3.5e-79 266.0 0.0 5.1e-79 265.4 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region RCC1_2 PF13540.1 KPI35492.1 - 0.14 11.8 0.7 9.3 6.0 0.0 3.2 4 0 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat CLAMP PF14769.1 KPI35492.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 RINGv PF12906.2 KPI35493.1 - 6.8e-07 29.2 0.8 6.8e-07 29.2 0.6 2.1 2 0 0 2 2 2 1 RING-variant domain zf-RanBP PF00641.13 KPI35493.1 - 0.1 11.7 0.1 0.16 11.0 0.1 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others PhnA_Zn_Ribbon PF08274.7 KPI35493.1 - 0.22 11.3 0.8 0.37 10.6 0.6 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon PHD PF00628.24 KPI35493.1 - 0.31 10.7 3.8 0.15 11.7 0.6 1.9 2 0 0 2 2 2 0 PHD-finger ATPase_gene1 PF09527.5 KPI35493.1 - 0.58 10.0 5.3 0.62 9.9 0.3 2.3 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) Glyco_hydro_2_C PF02836.12 KPI35494.1 - 1.7e-101 339.1 0.2 2.2e-101 338.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 KPI35494.1 - 3.2e-59 200.2 0.0 5.6e-36 123.9 0.0 3.2 2 1 1 3 3 3 3 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 KPI35494.1 - 4.1e-52 176.1 0.5 8.4e-52 175.0 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain UNC45-central PF11701.3 KPI35495.1 - 8.1e-33 113.2 0.1 2.9e-31 108.2 0.0 3.4 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central Arm PF00514.18 KPI35495.1 - 0.00083 19.0 13.3 0.71 9.7 0.1 7.4 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KPI35495.1 - 0.1 12.6 10.1 0.2 11.8 0.1 5.9 6 0 0 6 6 6 0 HEAT repeat Proteasome PF00227.21 KPI35496.1 - 1.4e-56 190.8 0.0 1.1e-31 109.5 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KPI35496.1 - 4.8e-11 41.7 0.0 1.2e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PIR PF00399.14 KPI35496.1 - 0.044 13.1 18.5 0.66 9.4 2.4 2.9 2 0 0 2 2 2 0 Yeast PIR protein repeat Helicase_C PF00271.26 KPI35497.1 - 2.6e-09 36.7 0.0 6.1e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.3 KPI35497.1 - 6.4e-09 35.1 0.2 1.4e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Zot PF05707.7 KPI35497.1 - 0.092 12.2 0.0 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) TK PF00265.13 KPI35497.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase MatE PF01554.13 KPI35498.1 - 6.8e-28 97.3 6.7 6.8e-28 97.3 4.6 1.5 2 0 0 2 2 2 1 MatE Fasciclin PF02469.17 KPI35499.1 - 4.3e-38 130.2 0.5 5.3e-24 84.6 0.1 2.4 2 0 0 2 2 2 2 Fasciclin domain DNA_pol_lambd_f PF10391.4 KPI35501.1 - 0.09 12.3 0.7 0.38 10.3 0.1 2.2 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda FHA PF00498.21 KPI35502.1 - 3.8e-15 55.7 0.0 3.7e-13 49.3 0.0 2.5 2 0 0 2 2 2 1 FHA domain zf-RING_2 PF13639.1 KPI35502.1 - 1.1e-07 31.4 8.0 2.1e-07 30.6 5.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KPI35502.1 - 0.00024 20.7 8.7 0.0005 19.6 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KPI35502.1 - 0.00037 20.5 4.2 0.00082 19.4 2.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger PHD PF00628.24 KPI35502.1 - 0.0027 17.3 5.5 0.0051 16.4 3.8 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_5 PF14634.1 KPI35502.1 - 0.013 15.1 6.9 0.024 14.3 4.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 KPI35502.1 - 0.031 14.0 3.7 0.14 12.0 2.6 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KPI35502.1 - 0.074 13.1 9.2 0.14 12.2 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRN7 PF11781.3 KPI35502.1 - 0.083 12.4 0.2 0.23 11.0 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-HC5HC2H PF13771.1 KPI35502.1 - 0.92 9.7 5.4 1.7 8.8 3.7 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 KPI35502.1 - 2.2 8.3 6.3 6.6 6.8 4.4 1.9 1 0 0 1 1 1 0 RING-like domain FH2 PF02181.18 KPI35504.1 - 0.044 12.6 0.3 0.068 12.0 0.2 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF948 PF06103.6 KPI35504.1 - 0.054 13.3 0.6 0.17 11.7 0.4 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HTH_AraC PF00165.18 KPI35504.1 - 0.12 12.2 0.1 0.39 10.6 0.0 1.9 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HEAT_2 PF13646.1 KPI35505.1 - 7.1e-33 112.7 4.1 5.4e-17 61.8 0.0 3.7 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.11 KPI35505.1 - 1.7e-20 71.3 1.0 0.0056 17.0 0.0 6.6 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 KPI35505.1 - 2.3e-11 43.8 8.1 0.0001 22.6 0.2 4.8 2 2 1 3 3 3 3 HEAT-like repeat HEAT PF02985.17 KPI35505.1 - 1.4e-08 34.1 4.2 0.093 12.8 0.0 5.7 6 0 0 6 6 6 3 HEAT repeat Arm PF00514.18 KPI35505.1 - 0.00078 19.1 0.1 1.4 8.8 0.0 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 KPI35505.1 - 0.017 15.0 0.8 1.6 8.8 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion RuvA_C PF07499.8 KPI35505.1 - 0.019 15.1 0.4 13 6.0 0.0 3.7 3 0 0 3 3 3 0 RuvA, C-terminal domain F-box-like PF12937.2 KPI35507.1 - 0.018 14.7 0.2 0.033 13.9 0.2 1.4 1 0 0 1 1 1 0 F-box-like Aa_trans PF01490.13 KPI35508.1 - 3.1e-50 170.8 34.6 3.7e-50 170.6 24.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4604 PF15377.1 KPI35510.1 - 1.3e-20 74.1 18.7 1.6e-20 73.9 13.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Lin-8 PF03353.10 KPI35510.1 - 0.4 9.9 7.8 0.49 9.6 5.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MatE PF01554.13 KPI35511.1 - 4.7e-32 110.8 9.8 6.7e-32 110.3 6.8 1.2 1 0 0 1 1 1 1 MatE HAD PF12710.2 KPI35512.1 - 3.9e-09 36.9 0.0 8.8e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KPI35512.1 - 0.00011 22.4 0.0 0.0056 16.9 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KPI35512.1 - 0.0051 16.0 0.0 0.035 13.2 0.0 2.0 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.7 KPI35512.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Nucleoporin_FG PF13634.1 KPI35513.1 - 0.00012 22.3 15.4 0.00012 22.3 10.6 1.8 2 0 0 2 2 2 1 Nucleoporin FG repeat region RPAP3_C PF13877.1 KPI35513.1 - 0.1 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 MIP PF00230.15 KPI35514.1 - 1.5e-43 148.8 22.4 1.9e-43 148.5 15.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF3522 PF12036.3 KPI35514.1 - 0.32 10.7 8.4 0.18 11.6 0.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3522) Pkinase PF00069.20 KPI35517.1 - 3.2e-33 115.0 0.0 4e-30 104.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KPI35517.1 - 1e-20 73.8 0.0 1.5e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KPI35517.1 - 6.2e-05 22.8 0.0 0.00021 21.1 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KPI35517.1 - 0.00023 20.2 0.0 0.00045 19.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KPI35517.1 - 0.018 14.1 0.0 0.046 12.7 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KPI35517.1 - 0.037 12.8 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 KPI35517.1 - 0.12 11.6 0.0 0.36 10.1 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Sugar_tr PF00083.19 KPI35518.1 - 2.5e-94 316.3 14.6 2.9e-94 316.1 10.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI35518.1 - 3.9e-20 71.8 28.0 3.9e-20 71.8 19.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily She9_MDM33 PF05546.6 KPI35521.1 - 2.6e-88 294.9 5.7 2.6e-88 294.9 3.9 1.9 2 0 0 2 2 2 1 She9 / Mdm33 family PsbH PF00737.15 KPI35521.1 - 0.0081 15.7 0.8 0.017 14.7 0.6 1.4 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein DUF1395 PF07160.7 KPI35521.1 - 0.01 15.3 1.0 0.025 14.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) SPX PF03105.14 KPI35521.1 - 3 7.5 9.2 12 5.5 6.4 1.9 1 1 0 1 1 1 0 SPX domain G-patch PF01585.18 KPI35522.1 - 7e-08 32.1 0.1 1.6e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 G-patch domain Adaptin_binding PF10199.4 KPI35524.1 - 2.4e-05 24.6 3.8 0.00029 21.1 2.7 2.3 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 UCR_TM PF02921.9 KPI35525.1 - 1.2e-19 70.3 1.5 2.5e-19 69.2 1.1 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 KPI35525.1 - 1.2e-17 63.2 0.0 2e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF202 PF02656.10 KPI35526.1 - 1.7e-21 76.2 2.4 1.9e-21 76.0 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF202) MscS_TM PF12794.2 KPI35526.1 - 0.013 14.1 1.0 0.017 13.7 0.7 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 PMP22_Claudin PF00822.15 KPI35526.1 - 0.029 14.0 0.7 0.04 13.5 0.5 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family COX4_pro_2 PF07835.7 KPI35526.1 - 0.07 13.1 0.3 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV Claudin_2 PF13903.1 KPI35526.1 - 0.079 12.6 3.2 0.17 11.5 2.2 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction 2TM PF13239.1 KPI35526.1 - 0.12 12.4 0.3 0.27 11.3 0.1 1.7 1 1 1 2 2 2 0 2TM domain DUF373 PF04123.8 KPI35526.1 - 0.14 11.1 0.5 0.18 10.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Yip1 PF04893.12 KPI35526.1 - 0.5 9.8 4.4 0.4 10.1 0.8 1.9 1 1 1 2 2 2 0 Yip1 domain DUF3040 PF11239.3 KPI35526.1 - 0.75 9.8 5.3 4.7 7.3 1.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) DUF4131 PF13567.1 KPI35526.1 - 1.9 7.8 4.7 1.6 8.0 2.3 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) LPAM_2 PF13627.1 KPI35526.1 - 2.1 8.1 11.4 3.3 7.5 2.4 2.7 2 0 0 2 2 2 0 Prokaryotic lipoprotein-attachment site MFS_1 PF07690.11 KPI35527.1 - 4.8e-32 111.0 58.5 1.1e-31 109.9 40.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KPI35527.1 - 3.3e-07 28.8 23.6 5.6e-07 28.1 16.3 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF500 PF04366.7 KPI35527.1 - 0.015 14.7 0.4 0.032 13.6 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF500) DUF566 PF04484.7 KPI35527.1 - 0.34 10.3 4.9 0.49 9.8 3.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) GTP_EFTU PF00009.22 KPI35529.1 - 1.3e-20 73.6 0.0 2.8e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KPI35529.1 - 2.8e-14 53.0 0.0 8e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KPI35529.1 - 6e-10 39.1 1.6 9.2e-09 35.3 0.7 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KPI35529.1 - 0.0061 16.1 0.1 0.021 14.4 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 PduV-EutP PF10662.4 KPI35529.1 - 0.0065 15.9 0.2 0.55 9.7 0.0 3.1 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KPI35529.1 - 0.059 13.8 0.1 0.47 10.9 0.1 2.5 1 1 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 KPI35529.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase FAD_oxidored PF12831.2 KPI35530.1 - 3.8e-91 306.3 0.0 4.7e-91 306.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI35530.1 - 4.9e-05 22.3 1.1 0.00052 18.9 1.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KPI35530.1 - 0.0004 20.3 1.2 0.0015 18.5 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI35530.1 - 0.0028 16.5 2.3 0.0048 15.8 1.6 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KPI35530.1 - 0.0096 14.8 0.9 0.035 12.9 0.6 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KPI35530.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI35530.1 - 0.22 9.9 0.2 0.3 9.4 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 KPI35530.1 - 0.24 10.3 1.2 0.87 8.5 0.8 1.8 1 1 0 1 1 1 0 FAD binding domain WD40 PF00400.27 KPI35531.1 - 7.8e-33 111.1 2.5 2.3e-08 33.5 0.0 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 KPI35531.1 - 0.0086 15.8 0.0 2.9 7.7 0.0 4.2 4 2 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Avirulence PF03377.8 KPI35531.1 - 0.033 12.9 0.0 0.05 12.3 0.0 1.1 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA FliE PF02049.13 KPI35531.1 - 0.2 11.7 1.0 0.71 9.9 0.1 2.3 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE Cupin_2 PF07883.6 KPI35532.1 - 2.2e-07 30.2 1.1 6.1e-07 28.8 0.1 2.2 3 1 0 3 3 3 1 Cupin domain Cupin_1 PF00190.17 KPI35532.1 - 0.01 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Cupin Auxin_BP PF02041.11 KPI35532.1 - 0.042 13.2 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein Ank PF00023.25 KPI35533.1 - 0.0024 17.5 0.0 0.0079 15.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 KPI35533.1 - 0.083 13.1 0.0 0.88 9.9 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.1 KPI35533.1 - 0.1 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF1216 PF06746.6 KPI35533.1 - 0.3 10.8 3.1 0.83 9.4 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) Abhydrolase_6 PF12697.2 KPI35534.1 - 3.9e-06 26.9 0.4 0.0004 20.3 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 KPI35534.1 - 0.00022 20.7 0.1 0.0016 17.9 0.1 2.0 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KPI35534.1 - 0.00024 20.3 0.0 0.0015 17.7 0.0 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KPI35534.1 - 0.0091 15.5 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI35534.1 - 0.027 14.2 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family LRR_4 PF12799.2 KPI35536.1 - 6.6e-17 60.7 19.8 5.8e-06 25.7 0.8 6.5 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KPI35536.1 - 6.8e-10 38.7 2.8 0.00013 21.5 0.3 2.5 2 0 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.1 KPI35536.1 - 3.2e-09 36.4 30.2 0.00023 20.8 3.6 5.5 3 2 4 7 7 7 4 Leucine rich repeat LRR_1 PF00560.28 KPI35536.1 - 8.5e-06 25.1 23.1 3.1 8.1 1.3 8.8 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_7 PF13504.1 KPI35536.1 - 1.7e-05 24.2 24.7 2 9.0 0.7 9.3 9 0 0 9 9 9 3 Leucine rich repeat LRR_6 PF13516.1 KPI35536.1 - 0.00019 21.1 16.5 1.3 9.3 0.8 7.0 7 0 0 7 7 7 2 Leucine Rich repeat Pkinase PF00069.20 KPI35537.1 - 2.2e-37 128.6 0.0 3.3e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI35537.1 - 1.7e-12 46.9 0.0 3.7e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Sec1 PF00995.18 KPI35538.1 - 4.9e-124 415.0 0.0 5.7e-124 414.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family MFS_1 PF07690.11 KPI35539.1 - 9.8e-38 129.7 27.8 9.8e-38 129.7 19.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily LSM PF01423.17 KPI35540.1 - 1.5e-14 53.2 0.1 2e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KPI35540.1 - 0.029 14.2 0.1 0.04 13.8 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Tail_tube PF10618.4 KPI35540.1 - 0.056 13.1 0.0 0.09 12.5 0.0 1.4 1 1 0 1 1 1 0 Phage tail tube protein LSM PF01423.17 KPI35542.1 - 1.4e-17 62.9 0.1 1.7e-17 62.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain PIG-L PF02585.12 KPI35545.1 - 7.5e-26 91.1 1.3 1.4e-25 90.2 0.9 1.5 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase Actin PF00022.14 KPI35546.1 - 4.9e-91 305.0 0.0 1.1e-90 303.9 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KPI35546.1 - 0.086 11.4 0.0 2.5 6.5 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein DPM3 PF08285.6 KPI35548.1 - 2.4e-26 91.4 0.0 2.8e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1624 PF07786.7 KPI35548.1 - 0.074 12.3 0.4 0.081 12.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) LEAP-2 PF07359.6 KPI35548.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) p450 PF00067.17 KPI35549.1 - 1.5e-60 205.0 0.0 2.4e-60 204.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 KPI35550.1 - 1.3e-82 277.8 24.7 1.5e-82 277.5 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI35550.1 - 1.4e-30 106.2 27.7 1.4e-30 106.2 19.2 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KPI35550.1 - 9.1e-09 34.1 22.1 0.00035 19.1 4.7 3.3 2 1 1 3 3 3 3 MFS/sugar transport protein RseC_MucC PF04246.7 KPI35550.1 - 4.4 6.8 9.8 2.9 7.4 0.4 3.5 2 2 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC PGP_phosphatase PF09419.5 KPI35551.1 - 7.1e-42 142.6 0.0 2e-23 82.5 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 KPI35551.1 - 1.5e-07 31.0 0.0 2.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 KPI35551.1 - 0.00036 20.7 0.0 0.0018 18.5 0.0 1.9 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KPI35551.1 - 0.13 12.6 0.3 11 6.3 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase PrpF PF04303.8 KPI35555.1 - 8e-90 301.2 0.0 9.7e-90 300.9 0.0 1.0 1 0 0 1 1 1 1 PrpF protein MFS_1 PF07690.11 KPI35556.1 - 3.8e-21 75.2 44.7 5e-12 45.1 14.2 3.4 1 1 1 3 3 3 3 Major Facilitator Superfamily DUF1232 PF06803.7 KPI35556.1 - 0.0069 15.8 1.0 0.14 11.6 0.2 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1232) PBP PF01161.15 KPI35557.1 - 9.4e-07 28.7 0.0 2.4e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylethanolamine-binding protein Bac_rhamnosid PF05592.6 KPI35558.1 - 1.5e-22 79.4 0.4 1.7e-15 56.2 0.0 2.5 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 KPI35558.1 - 0.006 15.3 0.4 0.01 14.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Abhydrolase_3 PF07859.8 KPI35559.1 - 1e-50 172.2 0.0 1.6e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KPI35559.1 - 7.1e-08 31.6 0.1 2.3e-07 29.9 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family vWA-TerF-like PF10138.4 KPI35559.1 - 2.1e-05 24.4 0.0 3.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Peptidase_S9 PF00326.16 KPI35559.1 - 2.4e-05 23.6 0.0 0.001 18.3 0.0 2.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KPI35559.1 - 0.0024 17.6 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KPI35559.1 - 0.017 13.6 0.0 0.18 10.3 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DLH PF01738.13 KPI35559.1 - 0.019 14.2 0.0 0.082 12.1 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2424 PF10340.4 KPI35559.1 - 0.026 13.1 0.0 0.1 11.1 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Cullin_binding PF03556.10 KPI35560.1 - 2.6e-30 104.9 2.7 2.7e-30 104.8 1.3 1.4 2 0 0 2 2 2 1 Cullin binding SH3_9 PF14604.1 KPI35561.1 - 0.00018 21.0 0.0 0.00047 19.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KPI35561.1 - 0.0068 15.8 0.4 0.015 14.7 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KPI35561.1 - 0.074 12.4 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 SH3 domain Zn_clus PF00172.13 KPI35561.1 - 1.1 9.2 4.1 2.5 8.0 2.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Alb1 PF09135.6 KPI35562.1 - 4.2e-08 33.7 14.7 7e-07 29.8 10.2 2.4 1 1 0 1 1 1 1 Alb1 RYDR_ITPR PF01365.16 KPI35563.1 - 0.014 14.5 0.1 0.053 12.7 0.0 1.9 2 0 0 2 2 2 0 RIH domain zf-RING_2 PF13639.1 KPI35564.1 - 1.7e-07 30.9 10.8 3.9e-07 29.7 7.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KPI35564.1 - 2.2e-07 30.4 10.3 2.2e-07 30.4 7.2 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KPI35564.1 - 9.7e-06 25.1 8.9 2e-05 24.1 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) bZIP_1 PF00170.16 KPI35564.1 - 5.6e-05 23.0 20.1 0.012 15.5 0.2 5.2 1 1 3 5 5 5 2 bZIP transcription factor ATG16 PF08614.6 KPI35564.1 - 0.00016 21.6 32.9 0.015 15.0 9.3 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) zf-C3HC4_2 PF13923.1 KPI35564.1 - 0.00024 21.0 10.8 0.00066 19.6 7.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KPI35564.1 - 0.00029 20.8 7.4 0.0011 19.0 5.1 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger Filament PF00038.16 KPI35564.1 - 0.00048 19.7 24.6 0.0037 16.7 11.7 2.1 1 1 1 2 2 2 1 Intermediate filament protein Myosin_tail_1 PF01576.14 KPI35564.1 - 0.0011 16.8 28.5 0.0062 14.3 19.2 1.9 1 1 1 2 2 2 2 Myosin tail zf-RING_UBOX PF13445.1 KPI35564.1 - 0.0075 15.9 2.8 0.15 11.7 0.2 2.9 2 0 0 2 2 2 1 RING-type zinc-finger AAA_13 PF13166.1 KPI35564.1 - 0.0084 14.6 18.3 0.012 14.1 12.7 1.1 1 0 0 1 1 1 1 AAA domain Mod_r PF07200.8 KPI35564.1 - 0.0094 15.8 2.8 0.0094 15.8 2.0 3.2 1 1 2 3 3 3 1 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 KPI35564.1 - 0.01 15.4 33.2 0.57 9.7 4.9 2.3 1 1 1 2 2 2 0 IncA protein CCDC155 PF14662.1 KPI35564.1 - 0.022 14.3 28.3 0.081 12.5 9.8 2.8 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 DUF972 PF06156.8 KPI35564.1 - 0.023 15.0 19.9 0.45 10.8 2.8 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 KPI35564.1 - 0.024 14.4 25.9 0.033 13.9 2.8 4.1 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF812 PF05667.6 KPI35564.1 - 0.024 13.1 21.4 0.035 12.6 14.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_2 PF07716.10 KPI35564.1 - 0.036 13.8 25.4 0.98 9.2 0.3 6.1 5 1 1 6 6 6 0 Basic region leucine zipper DUF869 PF05911.6 KPI35564.1 - 0.048 11.9 23.0 0.17 10.1 15.9 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) zf-Apc11 PF12861.2 KPI35564.1 - 0.048 13.4 6.4 0.096 12.5 4.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF342 PF03961.8 KPI35564.1 - 0.059 11.7 16.6 0.023 13.1 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) GAS PF13851.1 KPI35564.1 - 0.14 11.3 23.0 0.029 13.5 11.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 KPI35564.1 - 0.19 10.7 27.9 1.4 7.8 9.4 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 AbiH PF14253.1 KPI35564.1 - 0.19 11.3 5.7 0.31 10.5 3.9 1.3 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH TMCO5 PF14992.1 KPI35564.1 - 0.2 10.7 25.0 0.97 8.5 3.8 2.9 1 1 2 3 3 3 0 TMCO5 family ADIP PF11559.3 KPI35564.1 - 0.22 11.4 33.4 0.36 10.7 9.0 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 KPI35564.1 - 0.24 10.5 12.3 1.3 8.1 4.3 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Gp-FAR-1 PF05823.7 KPI35564.1 - 0.47 10.4 6.9 1.7 8.5 4.2 2.2 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CENP-Q PF13094.1 KPI35564.1 - 0.55 10.2 27.8 0.21 11.6 3.0 3.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Fib_alpha PF08702.5 KPI35564.1 - 0.61 10.1 19.7 2.6 8.1 6.4 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Rab5-bind PF09311.6 KPI35564.1 - 0.66 9.8 31.4 3.6 7.4 12.2 3.1 1 1 1 2 2 2 0 Rabaptin-like protein HrpB7 PF09486.5 KPI35564.1 - 0.76 9.6 18.1 2.5 8.0 5.7 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.7 KPI35564.1 - 0.83 9.4 16.2 1.7 8.4 0.9 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Spc24 PF08286.6 KPI35564.1 - 1.1 9.0 22.3 0.18 11.5 0.7 3.3 2 1 0 2 2 1 0 Spc24 subunit of Ndc80 DUF2353 PF09789.4 KPI35564.1 - 1.1 8.4 22.1 1.7 7.8 15.1 1.5 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Spc7 PF08317.6 KPI35564.1 - 1.1 7.8 26.7 3.1 6.3 6.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TBPIP PF07106.8 KPI35564.1 - 1.1 8.7 22.9 1.5 8.3 2.5 2.9 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Erythro_esteras PF05139.9 KPI35564.1 - 1.1 8.3 7.2 2.1 7.4 5.0 1.4 1 0 0 1 1 1 0 Erythromycin esterase FUSC PF04632.7 KPI35564.1 - 1.4 7.2 17.1 4.7 5.5 7.6 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family COG2 PF06148.6 KPI35564.1 - 2.3 8.0 17.6 7.1 6.5 1.6 3.1 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Nup54 PF13874.1 KPI35564.1 - 2.5 7.7 18.7 6.5 6.4 0.1 2.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Kinesin-relat_1 PF12711.2 KPI35564.1 - 2.7 8.4 21.3 10 6.6 1.9 4.4 1 1 3 4 4 4 0 Kinesin motor Carbpep_Y_N PF05388.6 KPI35564.1 - 2.7 8.1 5.3 77 3.4 0.0 3.4 2 2 1 3 3 3 0 Carboxypeptidase Y pro-peptide zf-C3HC4 PF00097.20 KPI35564.1 - 3 7.5 18.3 0.52 10.0 8.5 2.8 3 1 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) DivIC PF04977.10 KPI35564.1 - 3 7.3 29.1 0.61 9.6 0.7 4.9 1 1 4 5 5 5 0 Septum formation initiator Cep57_CLD_2 PF14197.1 KPI35564.1 - 3 7.8 35.2 0.63 10.0 8.9 5.1 1 1 1 4 4 4 0 Centrosome localisation domain of PPC89 DUF4200 PF13863.1 KPI35564.1 - 3.4 7.6 23.3 1.1 9.2 7.1 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.14 KPI35564.1 - 3.7 5.2 15.6 4.2 5.1 2.9 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 KPI35564.1 - 3.8 7.1 22.0 4.2 6.9 8.8 2.4 1 1 1 2 2 2 0 Mnd1 family KxDL PF10241.4 KPI35564.1 - 4.1 7.3 15.7 0.37 10.7 2.2 3.2 1 1 3 4 4 4 0 Uncharacterized conserved protein Rootletin PF15035.1 KPI35564.1 - 4.4 7.2 30.6 2.9 7.8 11.4 2.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Kinetocho_Slk19 PF12709.2 KPI35564.1 - 4.9 7.2 19.7 3.1 7.9 1.5 4.0 1 1 3 4 4 4 0 Central kinetochore-associated DUF4407 PF14362.1 KPI35564.1 - 5.9 5.7 19.3 6.7 5.5 9.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.17 KPI35564.1 - 6.2 6.8 19.4 3.3 7.7 1.0 3.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HAUS-augmin3 PF14932.1 KPI35564.1 - 6.8 5.8 27.2 4.9 6.2 6.2 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 ZYG-11_interact PF05884.7 KPI35564.1 - 6.8 5.6 6.7 13 4.7 1.2 2.8 1 1 2 3 3 3 0 Interactor of ZYG-11 IFT20 PF14931.1 KPI35564.1 - 6.8 6.6 16.4 1.7 8.5 3.0 3.2 1 1 2 3 3 3 0 Intraflagellar transport complex B, subunit 20 DUF3186 PF11382.3 KPI35564.1 - 7.6 5.5 12.2 3.9 6.5 0.8 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3186) DUF3584 PF12128.3 KPI35564.1 - 8 3.6 26.3 0.53 7.5 12.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) SlyX PF04102.7 KPI35564.1 - 8.2 6.8 16.2 0.19 12.1 0.4 3.7 2 1 2 4 4 4 0 SlyX Acyl-CoA_dh_C PF12806.2 KPI35564.1 - 8.8 6.2 7.3 9.9 6.0 0.2 3.3 1 1 3 4 4 4 0 Acetyl-CoA dehydrogenase C-terminal like Asparaginase_2 PF01112.13 KPI35565.1 - 1.9e-31 109.0 5.2 3.4e-18 65.4 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Collagen PF01391.13 KPI35566.1 - 2.1e-12 46.3 55.9 2.1e-07 30.3 18.1 3.3 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) WSC PF01822.14 KPI35566.1 - 0.00054 19.8 9.8 0.00084 19.2 6.8 1.3 1 0 0 1 1 1 1 WSC domain CBFD_NFYB_HMF PF00808.18 KPI35567.1 - 2.8e-11 43.2 0.3 4.9e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KPI35567.1 - 0.0034 17.4 0.2 0.0056 16.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Abhydrolase_6 PF12697.2 KPI35568.1 - 9.1e-21 74.7 0.3 1.2e-20 74.4 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI35568.1 - 4e-08 33.1 0.0 6.5e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3530 PF12048.3 KPI35568.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Amidase PF01425.16 KPI35569.1 - 8.8e-60 202.7 1.5 9.9e-59 199.3 0.1 2.0 1 1 1 2 2 2 2 Amidase ORMDL PF04061.9 KPI35570.1 - 5.6e-57 191.0 1.6 6.6e-57 190.8 1.1 1.1 1 0 0 1 1 1 1 ORMDL family KASH PF10541.4 KPI35570.1 - 0.074 12.9 0.5 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Nuclear envelope localisation domain UAA PF08449.6 KPI35571.1 - 2.1e-77 260.0 3.8 2.6e-77 259.7 2.6 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 KPI35571.1 - 0.00044 19.4 0.0 0.00092 18.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 KPI35571.1 - 0.0015 18.1 7.7 0.0015 18.1 5.3 2.6 3 1 0 3 3 3 1 Triose-phosphate Transporter family EmrE PF13536.1 KPI35571.1 - 0.0024 18.0 17.3 0.051 13.7 2.7 2.9 2 1 1 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 KPI35571.1 - 0.0039 17.2 26.4 0.63 10.0 1.3 3.8 3 1 1 4 4 4 3 EamA-like transporter family DUF1282 PF06930.7 KPI35571.1 - 0.36 10.4 16.5 0.13 11.8 2.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1282) MFS_1 PF07690.11 KPI35572.1 - 4.2e-27 94.7 17.7 4.2e-27 94.7 12.3 2.1 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KPI35572.1 - 4.7e-07 28.3 1.3 4.7e-07 28.3 0.9 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sds3 PF08598.6 KPI35573.1 - 4.4e-36 124.3 12.9 1.1e-35 123.1 8.9 1.7 1 1 0 1 1 1 1 Sds3-like EDR1 PF14381.1 KPI35573.1 - 0.11 12.0 0.2 0.21 11.1 0.2 1.4 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 PDGF_N PF04692.8 KPI35573.1 - 1.3 9.5 8.7 1.4 9.4 0.1 3.8 4 0 0 4 4 4 0 Platelet-derived growth factor, N terminal region AXE1 PF05448.7 KPI35574.1 - 7.4e-13 47.6 0.0 1.4e-09 36.9 0.0 3.0 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_5 PF12695.2 KPI35574.1 - 1.3e-12 47.7 0.0 2.5e-12 46.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI35574.1 - 3.3e-12 46.7 0.0 4.3e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI35574.1 - 1.4e-08 34.2 0.0 3.4e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KPI35574.1 - 2.2e-08 33.8 0.0 5.1e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 KPI35574.1 - 7.7e-06 25.7 0.0 0.00025 20.8 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 KPI35574.1 - 0.019 14.2 0.0 0.19 10.9 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KPI35574.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase HLH PF00010.21 KPI35575.1 - 5.4e-14 51.6 0.3 1.3e-13 50.3 0.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF106 PF01956.11 KPI35576.1 - 1.3e-57 194.0 0.1 2e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF106 Nop14 PF04147.7 KPI35578.1 - 5.2e-241 802.0 25.1 6.2e-241 801.8 17.4 1.0 1 0 0 1 1 1 1 Nop14-like family C2 PF00168.25 KPI35579.1 - 5.4e-15 54.9 0.0 2.3e-12 46.5 0.1 2.4 2 0 0 2 2 2 2 C2 domain Na_Ca_ex PF01699.19 KPI35580.1 - 6e-23 80.9 19.6 4.7e-17 61.9 2.5 3.5 3 1 0 3 3 3 2 Sodium/calcium exchanger protein DUF443 PF04276.7 KPI35580.1 - 0.026 13.9 0.1 0.026 13.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF443) DUF3742 PF12553.3 KPI35580.1 - 0.13 12.6 2.5 2.5 8.6 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3742) DUF3278 PF11683.3 KPI35580.1 - 9.1 6.2 13.8 7.6 6.5 0.1 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3278) Form_Nir_trans PF01226.12 KPI35581.1 - 7.2e-78 260.9 18.6 8.3e-78 260.7 12.9 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Ycf4 PF02392.11 KPI35581.1 - 0.17 11.1 5.1 0.82 8.9 0.4 2.2 2 0 0 2 2 2 0 Ycf4 HET PF06985.6 KPI35582.1 - 2.8e-22 79.3 0.1 2.2e-21 76.4 0.0 2.2 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Gly_kinase PF02595.10 KPI35583.1 - 1.6e-108 362.7 7.9 1.9e-108 362.5 5.5 1.0 1 0 0 1 1 1 1 Glycerate kinase family Ureidogly_hydro PF04115.7 KPI35584.1 - 1.4e-40 138.3 0.0 1.6e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase OB_NTP_bind PF07717.11 KPI35585.1 - 1.1e-23 83.1 0.0 8.2e-23 80.4 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KPI35585.1 - 1.4e-23 82.8 0.1 1.1e-22 79.9 0.0 2.6 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KPI35585.1 - 1.2e-11 44.3 0.0 3.7e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KPI35585.1 - 7.9e-08 31.9 0.1 1.7e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KPI35585.1 - 0.00011 22.3 0.1 0.0003 20.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KPI35585.1 - 0.00031 20.6 0.2 0.3 10.8 0.0 2.9 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit T2SE PF00437.15 KPI35585.1 - 0.00047 19.1 0.0 0.0012 17.7 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 KPI35585.1 - 0.0013 18.2 0.4 0.0037 16.7 0.3 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_14 PF13173.1 KPI35585.1 - 0.0015 18.4 0.3 0.012 15.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 KPI35585.1 - 0.0019 17.9 0.0 0.0044 16.7 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain DUF2075 PF09848.4 KPI35585.1 - 0.0022 17.0 0.0 0.0054 15.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 KPI35585.1 - 0.014 14.5 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 KPI35585.1 - 0.039 13.6 1.0 0.69 9.5 0.1 2.6 3 0 0 3 3 3 0 NACHT domain Miro PF08477.8 KPI35585.1 - 0.084 13.3 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 KPI35585.1 - 0.12 12.6 1.3 0.25 11.6 0.0 2.3 3 0 0 3 3 1 0 ABC transporter G-alpha PF00503.15 KPI35585.1 - 6.5 5.3 8.3 0.075 11.7 0.4 1.7 2 0 0 2 2 2 0 G-protein alpha subunit Peptidase_M14 PF00246.19 KPI35586.1 - 8.1e-66 222.4 0.0 2.8e-65 220.7 0.0 1.8 1 1 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 KPI35586.1 - 0.00013 21.5 0.1 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Prefoldin_2 PF01920.15 KPI35587.1 - 1.5e-21 76.1 4.3 2.1e-21 75.6 3.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit MutS_IV PF05190.13 KPI35587.1 - 0.00044 20.3 0.6 0.0093 16.1 0.0 2.2 2 0 0 2 2 2 1 MutS family domain IV Spc24 PF08286.6 KPI35587.1 - 0.0091 15.6 4.2 0.024 14.3 0.3 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Prefoldin PF02996.12 KPI35587.1 - 0.01 15.4 4.0 1.5 8.4 2.8 2.4 1 1 0 1 1 1 0 Prefoldin subunit Spuma_A9PTase PF03539.9 KPI35587.1 - 0.024 14.5 0.6 0.04 13.8 0.0 1.5 2 0 0 2 2 2 0 Spumavirus aspartic protease (A9) UBN2 PF14223.1 KPI35587.1 - 0.083 12.6 0.3 0.29 10.9 0.1 2.0 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type DUF512 PF04459.7 KPI35587.1 - 0.1 11.6 0.1 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF512) MIF4G_like_2 PF09090.6 KPI35587.1 - 0.11 11.7 0.3 0.23 10.6 0.1 1.5 1 1 0 1 1 1 0 MIF4G like Tho2 PF11262.3 KPI35587.1 - 0.11 11.5 0.4 0.57 9.1 0.2 1.9 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Cortex-I_coil PF09304.5 KPI35587.1 - 0.15 12.1 2.4 1.8 8.6 0.2 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF964 PF06133.6 KPI35587.1 - 0.18 11.7 4.6 0.51 10.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF964) DUF2205 PF10224.4 KPI35587.1 - 0.24 10.9 2.3 0.21 11.2 0.3 1.8 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) PspA_IM30 PF04012.7 KPI35587.1 - 0.25 10.6 4.4 4.4 6.5 0.2 2.1 2 0 0 2 2 2 0 PspA/IM30 family Syntaxin-6_N PF09177.6 KPI35587.1 - 0.33 11.3 3.1 5.2 7.5 0.3 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal bZIP_Maf PF03131.12 KPI35587.1 - 3.9 7.8 6.3 15 5.9 1.5 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor Rho_Binding PF08912.6 KPI35587.1 - 8.8 6.7 7.0 3 8.2 0.4 2.2 2 0 0 2 2 2 0 Rho Binding Fungal_trans PF04082.13 KPI35588.1 - 1e-12 47.4 1.6 1.2e-12 47.2 0.7 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF917 PF06032.7 KPI35589.1 - 1e-111 372.9 0.6 2.2e-111 371.8 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 KPI35589.1 - 7.1e-17 61.4 0.4 1.4e-16 60.5 0.3 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Scm3 PF10384.4 KPI35590.1 - 1.5e-17 62.7 0.2 4.5e-17 61.2 0.1 1.9 1 0 0 1 1 1 1 Centromere protein Scm3 zf-C2H2 PF00096.21 KPI35590.1 - 0.008 16.4 2.1 16 6.0 0.0 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI35590.1 - 0.021 15.1 5.9 1.8 9.0 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Cupin_2 PF07883.6 KPI35591.1 - 9.8e-06 24.9 0.3 5e-05 22.7 0.2 2.0 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KPI35591.1 - 0.00014 21.3 0.1 0.00051 19.4 0.0 1.7 1 1 2 3 3 3 1 Cupin MOSC_N PF03476.11 KPI35592.1 - 1.9e-17 63.1 0.0 3.4e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KPI35592.1 - 2.7e-10 39.8 0.0 4.6e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 MOSC domain HET PF06985.6 KPI35593.1 - 3.4e-15 56.4 3.3 5.5e-14 52.5 2.3 2.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans_2 PF11951.3 KPI35594.1 - 0.00011 20.9 3.4 0.014 13.9 0.5 2.9 2 1 0 2 2 2 2 Fungal specific transcription factor domain SAF PF08666.7 KPI35595.1 - 0.056 13.8 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 SAF domain TRI12 PF06609.8 KPI35596.1 - 1.6e-36 125.6 23.7 2e-36 125.3 16.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI35596.1 - 8.7e-23 80.5 43.7 8.7e-23 80.5 30.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI35596.1 - 3.6e-11 42.3 33.0 2.4e-08 32.9 8.5 3.2 2 2 0 2 2 2 2 Sugar (and other) transporter Glyco_hydro_15 PF00723.16 KPI35597.1 - 7.4e-76 255.4 0.1 9.5e-76 255.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KPI35597.1 - 2.9e-09 36.3 0.1 9.1e-09 34.8 0.1 1.9 1 0 0 1 1 1 1 Starch binding domain RICH PF05062.7 KPI35598.1 - 0.12 12.5 0.0 1.5 8.9 0.0 2.1 2 0 0 2 2 2 0 RICH domain Herpes_heli_pri PF05774.6 KPI35598.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus helicase-primase complex component DHquinase_I PF01487.10 KPI35599.1 - 1.5e-22 80.3 0.0 2.5e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 KPI35599.1 - 1.9e-17 63.0 0.0 3.8e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 KPI35599.1 - 2.3e-14 53.5 0.0 1.1e-13 51.3 0.0 2.1 1 1 1 2 2 2 1 Shikimate kinase Shikimate_DH PF01488.15 KPI35599.1 - 2.1e-09 37.5 0.0 5.1e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 KPI35599.1 - 0.00011 22.9 0.0 0.00046 20.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain ThiF PF00899.16 KPI35599.1 - 0.025 14.3 0.4 0.064 13.0 0.3 1.7 1 0 0 1 1 1 0 ThiF family Ribosomal_L7Ae PF01248.21 KPI35599.1 - 0.065 12.7 0.1 0.5 9.9 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SnoaL_4 PF13577.1 KPI35600.1 - 4.5e-06 26.6 1.3 6.4e-06 26.1 0.9 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KPI35600.1 - 0.0025 17.9 0.5 0.0041 17.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF2235 PF09994.4 KPI35601.1 - 3e-61 207.2 0.1 5.8e-38 130.8 0.0 2.4 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) APG6 PF04111.7 KPI35602.1 - 4.3e-117 390.6 0.1 5.2e-117 390.3 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 V_ATPase_I PF01496.14 KPI35602.1 - 0.0063 14.4 3.5 0.0086 13.9 2.4 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family IncA PF04156.9 KPI35602.1 - 0.11 12.1 17.0 0.24 10.9 11.8 1.5 1 0 0 1 1 1 0 IncA protein DUF4200 PF13863.1 KPI35602.1 - 0.17 11.8 14.7 0.29 11.0 10.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ADIP PF11559.3 KPI35602.1 - 0.53 10.1 13.7 1.3 8.9 9.5 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding FUSC PF04632.7 KPI35602.1 - 0.58 8.5 3.2 1.1 7.5 2.2 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family RRP7 PF12923.2 KPI35602.1 - 1.2 9.1 8.2 3.4 7.6 5.7 1.7 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) adh_short PF00106.20 KPI35603.1 - 2.9e-17 63.1 0.0 3.9e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI35603.1 - 1.5e-06 28.0 0.0 3.5e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 KR domain DUF4447 PF14590.1 KPI35603.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4447) S4 PF01479.20 KPI35604.1 - 8.4e-11 41.1 0.0 1.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 KPI35604.1 - 4.6e-07 30.1 1.9 1.1e-06 28.8 1.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Aldose_epim PF01263.15 KPI35605.1 - 1.1e-51 175.7 0.2 1.5e-51 175.3 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Rdx PF10262.4 KPI35607.1 - 3.1e-26 91.1 0.4 1.7e-25 88.8 0.2 1.9 1 1 0 1 1 1 1 Rdx family p450 PF00067.17 KPI35608.1 - 1.7e-46 158.7 0.0 2.1e-46 158.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3856 PF12968.2 KPI35608.1 - 0.085 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_11 PF13414.1 KPI35610.1 - 2.6e-13 49.3 8.7 3.3e-12 45.8 4.0 2.7 2 0 0 2 2 2 1 TPR repeat DUF4470 PF14737.1 KPI35610.1 - 4.3e-08 32.8 0.0 8.6e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.12 KPI35610.1 - 1.8e-06 27.3 11.0 0.0031 17.2 1.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KPI35610.1 - 3.1e-05 23.3 6.3 0.12 12.0 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KPI35610.1 - 9.8e-05 22.2 3.6 9.8e-05 22.2 2.5 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KPI35610.1 - 0.00065 20.3 8.4 0.00065 20.3 5.8 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 KPI35610.1 - 0.11 12.4 8.5 0.17 11.8 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KPI35610.1 - 0.59 10.0 3.5 4.2 7.3 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PH PF00169.24 KPI35611.1 - 5.2e-11 42.6 0.1 1.1e-10 41.5 0.1 1.6 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 KPI35611.1 - 0.52 7.7 0.1 0.75 7.2 0.1 1.1 1 0 0 1 1 1 0 Prominin DUF605 PF04652.11 KPI35612.1 - 0.043 13.2 7.4 0.05 12.9 5.1 1.0 1 0 0 1 1 1 0 Vta1 like CorA PF01544.13 KPI35613.1 - 4.6e-05 22.6 0.5 8.2e-05 21.7 0.3 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Sigma_1s PF02454.11 KPI35613.1 - 0.042 13.6 2.0 5.1 6.9 0.3 2.4 2 0 0 2 2 2 0 Sigma 1s protein Metallophos PF00149.23 KPI35614.1 - 7.1e-08 32.0 1.5 6.2e-07 29.0 1.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KPI35614.1 - 2.9e-06 27.2 0.3 7.1e-06 25.9 0.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Amidohydro_4 PF13147.1 KPI35615.1 - 4e-22 79.5 1.7 1e-21 78.2 1.2 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KPI35615.1 - 5.5e-16 59.1 0.1 3.8e-15 56.3 0.1 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KPI35615.1 - 4.2e-14 52.5 1.8 3e-10 39.8 0.2 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KPI35615.1 - 3.9e-10 39.3 0.1 1.3e-09 37.7 0.1 1.9 1 0 0 1 1 1 1 Amidohydrolase Abhydrolase_6 PF12697.2 KPI35616.1 - 1.8e-17 64.0 1.1 3.1e-17 63.2 0.7 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI35616.1 - 1.7e-09 37.5 0.1 2.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI35616.1 - 0.00025 20.6 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KPI35616.1 - 0.00047 19.7 0.0 0.00086 18.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI35616.1 - 0.00062 19.0 0.0 0.0036 16.5 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 KPI35616.1 - 0.034 13.5 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF1100 PF06500.6 KPI35616.1 - 0.038 12.5 0.0 0.047 12.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Sec66 PF09802.4 KPI35617.1 - 3.8e-47 160.1 2.5 6.9e-46 156.0 1.7 2.0 1 1 0 1 1 1 1 Preprotein translocase subunit Sec66 KorB PF08535.5 KPI35617.1 - 0.23 11.6 3.1 0.13 12.3 0.4 2.0 2 1 1 3 3 3 0 KorB domain CENP-Q PF13094.1 KPI35618.1 - 1.6e-20 73.7 13.3 2.4e-20 73.1 9.2 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.3 KPI35618.1 - 9.6 6.0 15.1 5.8 6.8 7.4 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding NAD_binding_2 PF03446.10 KPI35619.1 - 2.1e-28 99.1 0.1 4.1e-28 98.2 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KPI35619.1 - 9.9e-26 90.1 4.3 1e-16 61.1 0.4 2.3 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.13 KPI35619.1 - 4.6e-06 26.4 0.3 8.6e-06 25.5 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KPI35619.1 - 0.0011 18.4 0.0 0.0023 17.3 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 KPI35619.1 - 0.0077 15.3 0.2 0.024 13.7 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KPI35619.1 - 0.025 14.0 0.2 0.053 12.9 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KPI35619.1 - 0.032 13.9 0.4 0.15 11.7 0.1 2.3 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 KPI35619.1 - 0.067 13.1 0.2 0.29 11.1 0.0 2.3 2 1 0 2 2 2 0 TrkA-N domain Thioredoxin PF00085.15 KPI35620.1 - 6.3e-13 48.3 0.0 9.2e-13 47.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin malic PF00390.14 KPI35620.1 - 0.0099 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Thioredoxin_8 PF13905.1 KPI35620.1 - 0.031 14.3 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like DUF2515 PF10720.4 KPI35620.1 - 0.083 11.7 0.0 4.6 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2515) TraF PF13728.1 KPI35620.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Hydant_A_N PF05378.8 KPI35621.1 - 3.9e-29 101.3 0.0 6.1e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.13 KPI35621.1 - 4.1e-19 68.7 1.2 3e-17 62.6 0.0 2.2 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.15 KPI35621.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Aldedh PF00171.17 KPI35622.1 - 1.8e-139 465.0 1.1 1.7e-106 356.3 0.1 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family ERp29 PF07749.7 KPI35622.1 - 0.09 13.4 0.0 2.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain TPR_11 PF13414.1 KPI35623.1 - 2.8e-24 84.5 4.3 7.2e-09 35.1 0.3 4.4 3 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 KPI35623.1 - 8.5e-23 78.9 0.7 7.4e-06 25.3 0.1 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 KPI35623.1 - 2.9e-22 76.7 1.2 0.00027 20.6 0.1 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 KPI35623.1 - 1.3e-17 62.6 4.9 0.00012 22.3 0.2 5.7 3 3 2 5 5 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 KPI35623.1 - 1.5e-16 59.1 2.0 0.011 15.8 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KPI35623.1 - 4.3e-16 59.0 3.2 6.4e-06 26.6 0.6 4.4 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 KPI35623.1 - 2e-14 53.6 1.2 0.017 15.4 0.0 5.0 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 KPI35623.1 - 3.3e-13 49.3 1.7 5.8e-06 26.1 0.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KPI35623.1 - 8.6e-12 43.9 0.0 0.0018 17.9 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 KPI35623.1 - 2.9e-09 36.9 0.4 0.0071 16.4 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 KPI35623.1 - 3.8e-07 29.8 1.0 0.035 13.9 0.2 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KPI35623.1 - 7e-07 28.5 1.2 3 7.8 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KPI35623.1 - 9e-06 25.7 0.8 0.015 15.4 0.1 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KPI35623.1 - 1.1e-05 25.5 0.8 1.6 9.3 0.0 5.8 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 KPI35623.1 - 0.017 14.1 0.0 1.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 KPI35623.1 - 0.023 14.5 0.2 0.43 10.4 0.1 3.0 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.7 KPI35623.1 - 0.081 12.4 1.6 2.4 7.7 0.0 3.4 3 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 AP_endonuc_2 PF01261.19 KPI35624.1 - 1.9e-25 89.4 0.2 2.7e-25 88.9 0.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF1161 PF06649.7 KPI35624.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) Nbas_N PF15492.1 KPI35624.1 - 0.13 11.3 0.0 2.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal adh_short_C2 PF13561.1 KPI35625.1 - 5.5e-28 98.3 0.0 6.6e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI35625.1 - 2.1e-27 96.0 0.4 3.1e-27 95.5 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI35625.1 - 5.9e-10 39.1 0.1 8.7e-10 38.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI35625.1 - 1.5e-05 24.5 0.1 2.4e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KPI35625.1 - 0.012 15.3 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KPI35625.1 - 0.079 12.9 0.2 0.96 9.4 0.0 2.3 2 1 0 2 2 2 0 NADH(P)-binding TFIIS_M PF07500.9 KPI35626.1 - 5.4e-21 74.8 1.7 1.1e-20 73.8 1.2 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KPI35626.1 - 3.3e-19 68.2 5.5 4.9e-19 67.6 3.8 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KPI35626.1 - 2.6e-11 42.8 0.1 5.8e-11 41.7 0.1 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Cytochrome_C554 PF13435.1 KPI35626.1 - 0.002 18.1 5.8 0.0061 16.6 4.0 1.8 1 0 0 1 1 1 1 Cytochrome c554 and c-prime Borrelia_REV PF03978.8 KPI35626.1 - 0.0073 16.0 2.8 0.015 15.0 1.9 1.5 1 0 0 1 1 1 1 Borrelia burgdorferi REV protein Herpes_BLLF1 PF05109.8 KPI35626.1 - 0.011 13.7 4.7 0.013 13.4 3.2 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Cytochrome_C7 PF14522.1 KPI35626.1 - 0.093 12.3 3.1 0.22 11.1 2.2 1.6 1 0 0 1 1 1 0 Cytochrome c7 Cytochrom_NNT PF03264.9 KPI35626.1 - 0.16 11.3 5.0 0.31 10.4 3.5 1.4 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region GST_C PF00043.20 KPI35628.1 - 3.7e-14 52.4 0.1 8.5e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KPI35628.1 - 6.6e-12 45.4 0.0 2.1e-11 43.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KPI35628.1 - 1.1e-10 41.5 0.0 3.2e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI35628.1 - 5e-09 36.0 0.0 1.3e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KPI35628.1 - 5.7e-09 35.7 0.0 1.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KPI35628.1 - 1.4e-07 31.8 0.2 3.2e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DNA_pol_A PF00476.15 KPI35628.1 - 0.043 12.4 0.1 0.065 11.8 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase family A Acyl_transf_3 PF01757.17 KPI35629.1 - 0.069 11.9 0.0 0.073 11.8 0.0 1.1 1 0 0 1 1 1 0 Acyltransferase family DUF3818 PF12825.2 KPI35630.1 - 1.5e-136 454.5 1.0 2.4e-136 453.9 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KPI35630.1 - 3.8e-42 143.1 0.3 8.1e-42 142.0 0.2 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.19 KPI35630.1 - 4.4e-13 49.0 0.3 1.7e-12 47.1 0.0 2.2 2 0 0 2 2 2 1 PX domain DUF3628 PF12300.3 KPI35630.1 - 0.012 15.6 0.4 0.012 15.6 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) RRN3 PF05327.6 KPI35630.1 - 2.2 6.2 10.3 0.025 12.7 0.1 2.6 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor RRN3 adh_short PF00106.20 KPI35632.1 - 8e-20 71.4 4.4 8.6e-20 71.3 1.5 2.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI35632.1 - 1.2e-18 67.7 0.0 1.7e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KPI35632.1 - 2.7e-10 40.5 0.3 4.9e-10 39.7 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KPI35632.1 - 2.8e-10 40.1 4.2 4.7e-08 32.8 1.6 3.0 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 KPI35632.1 - 4.9e-10 39.2 0.1 3e-09 36.6 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI35632.1 - 4.3e-06 25.6 0.1 6.5e-06 25.0 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KPI35632.1 - 6.9e-05 21.8 0.1 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 KPI35632.1 - 0.00031 20.0 0.7 0.00049 19.4 0.5 1.3 1 0 0 1 1 1 1 NmrA-like family 3HCDH_N PF02737.13 KPI35632.1 - 0.0021 17.7 0.2 0.0036 16.9 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KPI35632.1 - 0.0024 17.8 0.2 0.0039 17.1 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain DapB_N PF01113.15 KPI35632.1 - 0.0059 16.5 0.3 0.01 15.7 0.2 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus AlaDh_PNT_C PF01262.16 KPI35632.1 - 0.017 14.7 0.3 0.029 13.9 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Saccharop_dh PF03435.13 KPI35632.1 - 0.022 13.7 0.4 0.031 13.2 0.3 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DFP PF04127.10 KPI35632.1 - 0.028 14.0 0.8 0.086 12.4 0.2 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein 2-Hacid_dh_C PF02826.14 KPI35632.1 - 0.031 13.4 0.4 0.14 11.3 0.2 2.1 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KPI35632.1 - 0.033 13.1 0.8 0.13 11.1 0.5 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.1 KPI35632.1 - 0.042 14.1 0.2 0.48 10.6 0.1 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Rossmann-like PF10727.4 KPI35632.1 - 0.078 12.6 0.3 0.16 11.7 0.1 1.6 2 0 0 2 2 1 0 Rossmann-like domain F420_oxidored PF03807.12 KPI35632.1 - 0.089 13.2 0.2 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent LysM PF01476.15 KPI35633.1 - 1.8e-05 24.5 0.0 4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 LysM domain Fungal_trans PF04082.13 KPI35634.1 - 1.6e-36 125.5 0.6 2.8e-36 124.7 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HTH_20 PF12840.2 KPI35634.1 - 0.039 13.7 0.1 1.2 8.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain APH PF01636.18 KPI35635.1 - 1.8e-09 37.6 0.1 2.5e-09 37.2 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KPI35635.1 - 1.1e-05 25.0 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase PALP PF00291.20 KPI35636.1 - 5.5e-40 137.4 0.0 6.9e-29 101.0 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme GMC_oxred_N PF00732.14 KPI35636.1 - 0.024 13.7 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase FAD_binding_2 PF00890.19 KPI35637.1 - 1.5e-80 271.1 0.2 1.8e-80 270.8 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 KPI35637.1 - 5.1e-20 71.0 2.3 1.1e-18 66.8 0.0 3.4 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KPI35637.1 - 5.9e-13 48.4 0.3 8.8e-12 44.5 0.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KPI35637.1 - 6.1e-09 35.4 0.1 1.8e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI35637.1 - 1.2e-08 34.8 0.5 7.5e-08 32.2 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI35637.1 - 1.4e-05 25.0 0.4 0.0017 18.2 0.3 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI35637.1 - 3.3e-05 22.5 3.4 0.00011 20.8 0.6 2.7 2 1 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KPI35637.1 - 9.2e-05 21.6 0.3 0.013 14.6 0.0 2.9 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.17 KPI35637.1 - 0.00031 19.7 0.6 0.1 11.4 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KPI35637.1 - 0.0035 17.4 0.5 0.011 15.8 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KPI35637.1 - 0.0065 15.5 0.3 0.025 13.6 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.19 KPI35637.1 - 0.017 14.2 0.1 1.8 7.5 0.0 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase GDI PF00996.13 KPI35637.1 - 0.04 12.2 0.1 0.068 11.4 0.1 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox PF00070.22 KPI35637.1 - 0.083 13.3 0.3 1.7 9.0 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4341 PF14241.1 KPI35637.1 - 5.6 6.7 7.6 3.1 7.5 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4341) AP_endonuc_2 PF01261.19 KPI35638.1 - 1.1e-25 90.2 0.0 1.4e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Phage_P2_GpU PF06995.6 KPI35638.1 - 0.0067 15.8 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Phage P2 GpU BBS2_C PF14782.1 KPI35638.1 - 0.16 10.4 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal DAO PF01266.19 KPI35642.1 - 8.8e-31 107.0 5.6 8.6e-30 103.8 3.8 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase DUF3546 PF12066.3 KPI35642.1 - 9.2e-27 93.2 5.0 9.2e-27 93.2 3.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 KPI35642.1 - 2.6e-22 78.1 0.0 6.9e-22 76.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 KPI35642.1 - 3.9e-09 37.0 2.2 1e-08 35.6 1.5 1.7 1 0 0 1 1 1 1 Arsenite-resistance protein 2 Pyr_redox_3 PF13738.1 KPI35642.1 - 0.0045 17.0 0.0 0.26 11.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI35642.1 - 0.17 10.2 0.1 0.73 8.2 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 KPI35642.1 - 1.9 8.2 6.1 16 5.2 0.0 3.6 3 1 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KPI35643.1 - 6.9e-13 48.3 0.0 9.3e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI35643.1 - 4.1e-09 35.8 1.1 0.0012 17.8 0.4 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KPI35643.1 - 7.7e-06 24.6 1.6 0.058 11.8 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 KPI35643.1 - 0.00013 21.9 1.8 0.00028 20.8 1.1 1.7 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI35643.1 - 0.00025 20.0 1.0 0.00079 18.3 0.6 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KPI35643.1 - 0.00074 18.5 0.0 0.0015 17.5 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 KPI35643.1 - 0.0008 19.7 2.2 0.74 10.2 0.4 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI35643.1 - 0.001 19.0 0.6 0.0025 17.7 0.4 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI35643.1 - 0.0015 18.6 0.1 0.0037 17.3 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI35643.1 - 0.046 12.7 0.2 0.07 12.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 KPI35643.1 - 0.055 12.3 1.8 0.096 11.5 1.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KPI35643.1 - 0.15 11.7 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KPI35643.1 - 0.33 10.7 1.5 2.2 8.0 0.2 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding SnoaL PF07366.7 KPI35644.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase SLAC1 PF03595.12 KPI35645.1 - 1e-69 234.7 42.2 1.2e-69 234.5 29.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SPC25 PF06703.6 KPI35645.1 - 3.4 7.2 6.0 5.4 6.5 0.2 2.7 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) PX PF00787.19 KPI35646.1 - 5.8e-18 64.7 0.4 2.2e-17 62.8 0.1 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KPI35646.1 - 8e-09 35.1 7.6 6e-06 25.6 0.2 2.1 1 1 1 2 2 2 2 Vps5 C terminal like BAR PF03114.13 KPI35646.1 - 0.00022 20.8 3.3 0.00051 19.6 2.3 1.6 1 1 0 1 1 1 1 BAR domain Hrs_helical PF12210.3 KPI35646.1 - 0.0033 17.6 0.0 0.014 15.6 0.0 2.0 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF1664 PF07889.7 KPI35646.1 - 0.12 12.1 1.0 5.3 6.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 KPI35646.1 - 0.16 10.8 1.1 13 4.6 0.0 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 UCH PF00443.24 KPI35647.1 - 3.5e-45 154.2 0.2 4.6e-44 150.5 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KPI35647.1 - 1.2e-13 51.1 0.0 7.7e-06 25.5 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 KPI35647.1 - 2.5e-11 42.8 0.7 7.2e-11 41.3 0.5 1.9 1 0 0 1 1 1 1 A repeated domain in UCH-protein adh_short PF00106.20 KPI35648.1 - 2.7e-20 72.9 0.4 3.4e-20 72.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI35648.1 - 1.9e-09 37.6 0.1 2.4e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI35648.1 - 4.7e-08 32.9 0.3 5.9e-08 32.5 0.2 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KPI35648.1 - 0.063 12.2 0.3 0.31 9.9 0.1 2.0 2 1 0 2 2 2 0 Male sterility protein NAD_binding_10 PF13460.1 KPI35648.1 - 0.074 13.0 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding 3H PF02829.9 KPI35648.1 - 0.11 12.5 0.1 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 3H domain Sugar_tr PF00083.19 KPI35649.1 - 3e-94 316.1 26.4 3.8e-94 315.8 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI35649.1 - 9.5e-26 90.3 31.7 4.4e-17 61.8 5.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4063 PF13272.1 KPI35649.1 - 0.012 15.3 0.1 0.037 13.8 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4063) adh_short PF00106.20 KPI35650.1 - 1.6e-28 99.7 0.1 4.2e-21 75.5 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KPI35650.1 - 2.8e-20 73.0 0.0 4.2e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI35650.1 - 1.7e-06 27.7 0.1 2.1e-05 24.2 0.1 2.3 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KPI35650.1 - 0.12 12.2 0.5 0.69 9.7 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Transp_cyt_pur PF02133.10 KPI35651.1 - 1.9e-57 194.8 13.9 2.1e-57 194.6 9.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PPR_2 PF13041.1 KPI35656.1 - 1.3e-09 37.9 0.0 0.0017 18.2 0.0 4.7 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.1 KPI35656.1 - 4.2e-05 23.4 4.6 1.3 9.4 0.0 6.5 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR PF01535.15 KPI35656.1 - 0.00032 20.4 10.1 0.93 9.6 0.0 6.3 7 0 0 7 7 7 2 PPR repeat MgtE_N PF03448.12 KPI35656.1 - 0.022 15.0 2.8 0.35 11.2 2.1 2.4 2 0 0 2 2 2 0 MgtE intracellular N domain Transp_cyt_pur PF02133.10 KPI35657.1 - 2.3e-34 118.7 13.2 2.8e-34 118.4 9.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3317 PF11779.3 KPI35657.1 - 1.9 7.9 6.3 3 7.3 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) ACT_3 PF10000.4 KPI35658.1 - 2.9e-18 65.3 0.1 5.4e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.1 KPI35658.1 - 2.1e-12 46.3 0.0 4.8e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 ACT domain CorA PF01544.13 KPI35658.1 - 2e-06 27.0 0.1 3.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.4 KPI35658.1 - 0.49 8.9 2.4 0.94 7.9 0.0 2.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) Tim17 PF02466.14 KPI35659.1 - 6.9e-11 42.2 7.8 1e-10 41.7 5.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4260 PF14079.1 KPI35661.1 - 3e-27 94.7 2.5 4e-12 45.9 0.0 3.0 3 0 0 3 3 3 3 Domain of unknown function (DUF4260) adh_short_C2 PF13561.1 KPI35662.1 - 4.5e-26 92.0 0.0 5.4e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI35662.1 - 3.6e-24 85.5 0.1 6.4e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI35662.1 - 3.7e-09 36.4 0.0 1.2e-08 34.8 0.0 1.7 1 1 1 2 2 2 1 KR domain WD40 PF00400.27 KPI35663.1 - 6.2e-14 51.2 1.1 0.00085 19.1 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Glucosamine_iso PF01182.15 KPI35664.1 - 6.6e-61 205.5 0.0 7.8e-61 205.2 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase UCH PF00443.24 KPI35665.1 - 6.8e-13 48.3 0.0 1.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KPI35665.1 - 8.8e-08 31.9 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PHD PF00628.24 KPI35665.1 - 0.002 17.7 0.9 0.002 17.7 0.6 3.3 4 0 0 4 4 4 1 PHD-finger YL1 PF05764.8 KPI35665.1 - 0.03 13.9 4.2 0.055 13.0 2.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein adh_short PF00106.20 KPI35666.1 - 9.2e-19 67.9 0.1 1.8e-18 66.9 0.0 1.5 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 KPI35666.1 - 2e-11 43.9 0.0 2.7e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI35666.1 - 1.1e-05 25.3 0.1 2.6e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.14 KPI35666.1 - 0.0021 17.2 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KPI35666.1 - 0.13 12.3 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THUMP PF02926.12 KPI35667.1 - 1e-09 38.4 1.8 2.4e-09 37.2 0.6 2.0 2 1 0 2 2 2 1 THUMP domain DUF2525 PF10733.4 KPI35667.1 - 0.0092 15.7 1.0 4.6 7.1 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2525) PLA2_B PF01735.13 KPI35669.1 - 6.2e-73 245.6 12.1 3.4e-71 239.9 8.4 2.1 1 1 0 1 1 1 1 Lysophospholipase catalytic domain DUF1479 PF07350.7 KPI35670.1 - 4.8e-113 377.7 0.0 5.6e-113 377.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 KPI35670.1 - 0.034 14.1 0.1 0.35 10.8 0.1 2.4 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) TIG PF01833.19 KPI35672.1 - 2.8e-12 46.4 0.0 7.4e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 IPT/TIG domain EXS PF03124.9 KPI35673.1 - 1.6e-87 293.7 25.8 2e-87 293.4 17.9 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KPI35673.1 - 1.8e-58 198.5 0.1 1.3e-57 195.7 0.0 2.1 2 1 0 2 2 2 1 SPX domain End3 PF12761.2 KPI35673.1 - 0.28 10.8 6.4 0.094 12.3 2.4 1.7 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF913 PF06025.7 KPI35674.1 - 0.09 11.5 0.4 0.12 11.1 0.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Arm PF00514.18 KPI35675.1 - 3.8e-06 26.5 13.2 0.031 14.0 0.0 7.6 9 0 0 9 9 9 2 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.3 KPI35675.1 - 1.1 9.1 3.1 11 5.9 0.1 3.7 3 2 2 5 5 5 0 V-ATPase subunit H RRM_5 PF13893.1 KPI35677.1 - 7.6e-05 22.4 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KPI35677.1 - 0.00012 21.6 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI35677.1 - 0.0014 18.5 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF202 PF02656.10 KPI35678.1 - 0.029 14.5 8.0 0.29 11.3 5.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) RseC_MucC PF04246.7 KPI35678.1 - 0.041 13.4 0.1 0.041 13.4 0.0 1.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC MFS_1 PF07690.11 KPI35680.1 - 3.4e-10 39.1 42.3 5.2e-09 35.2 7.8 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KPI35680.1 - 2.9e-05 22.4 1.1 2.9e-05 22.4 0.8 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF788 PF05620.6 KPI35680.1 - 0.097 12.5 1.1 0.34 10.7 0.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF788) TLC PF03219.9 KPI35682.1 - 0.0062 15.0 2.1 0.0073 14.8 1.5 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter Cation_efflux PF01545.16 KPI35682.1 - 4.2 6.3 8.5 12 4.8 5.9 1.7 1 1 0 1 1 1 0 Cation efflux family Cytochrom_B561 PF03188.11 KPI35684.1 - 0.00064 19.5 6.9 0.0017 18.1 4.8 1.8 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 Adeno_E3 PF06040.6 KPI35684.1 - 0.077 12.9 0.2 0.83 9.6 0.0 2.3 2 0 0 2 2 2 0 Adenovirus E3 protein Syndecan PF01034.15 KPI35684.1 - 0.2 11.2 3.2 0.42 10.3 0.0 2.7 3 0 0 3 3 3 0 Syndecan domain E1-E2_ATPase PF00122.15 KPI35685.1 - 8.3e-25 87.1 0.1 2.2e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KPI35685.1 - 2.3e-24 86.9 0.9 4.2e-24 86.1 0.7 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KPI35685.1 - 2.4e-08 34.3 0.0 6.9e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KPI35685.1 - 3.1e-08 33.6 0.0 8.1e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF3487 PF11990.3 KPI35685.1 - 0.14 11.5 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) p450 PF00067.17 KPI35686.1 - 7.6e-58 196.1 0.0 4.7e-36 124.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Isochorismatase PF00857.15 KPI35687.1 - 1.6e-28 99.8 0.0 6.7e-28 97.7 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.1 KPI35687.1 - 2.9e-24 85.9 0.0 5.2e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RILP PF11461.3 KPI35688.1 - 0.071 13.2 0.2 0.28 11.3 0.2 2.1 1 0 0 1 1 1 0 Rab interacting lysosomal protein FlxA PF14282.1 KPI35688.1 - 0.38 10.7 10.0 0.19 11.7 4.8 2.2 1 1 0 1 1 1 0 FlxA-like protein Ax_dynein_light PF10211.4 KPI35688.1 - 5.3 6.8 8.3 19 5.0 5.7 1.8 1 1 0 1 1 1 0 Axonemal dynein light chain GFA PF04828.9 KPI35689.1 - 5e-14 52.0 0.7 6.6e-14 51.6 0.5 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Sugar_tr PF00083.19 KPI35690.1 - 8.5e-68 228.9 25.1 2.5e-31 108.7 5.4 3.5 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 KPI35690.1 - 1.2e-17 63.7 30.3 9e-14 50.9 8.2 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI35690.1 - 1.2e-06 27.2 12.2 0.036 12.4 0.2 3.1 3 0 0 3 3 3 3 MFS/sugar transport protein TRI12 PF06609.8 KPI35690.1 - 0.023 12.9 5.4 0.0071 14.5 1.7 1.5 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Amastin PF07344.6 KPI35690.1 - 1.8 8.1 8.9 7 6.2 2.2 2.5 2 0 0 2 2 2 0 Amastin surface glycoprotein Cauli_VI PF01693.11 KPI35691.1 - 2.8e-34 116.8 1.8 2.7e-16 59.2 0.1 2.7 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 KPI35691.1 - 7.1e-25 87.8 0.8 9.3e-21 74.5 0.2 2.7 1 1 1 2 2 2 2 RNase H Sigma70_ner PF04546.8 KPI35691.1 - 0.07 12.7 3.6 0.14 11.7 2.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3680 PF12441.3 KPI35691.1 - 0.7 9.7 4.0 3.2 7.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3680) FAD_binding_4 PF01565.18 KPI35692.1 - 9.1e-32 109.4 0.0 1.6e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 KPI35692.1 - 9.8e-13 47.9 0.4 2e-12 46.9 0.2 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain Cytokin-bind PF09265.5 KPI35692.1 - 0.13 11.4 0.1 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding RNA12 PF10443.4 KPI35693.1 - 1.9e-165 550.5 1.2 2.9e-165 549.9 0.8 1.3 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.17 KPI35693.1 - 5.8e-06 25.8 0.0 2e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 KPI35693.1 - 0.00035 20.3 0.0 0.0015 18.2 0.0 2.0 1 1 0 1 1 1 1 Archaeal ATPase RRM_6 PF14259.1 KPI35693.1 - 0.01 15.8 0.0 0.046 13.7 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 KPI35693.1 - 0.012 15.3 0.0 0.04 13.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2487) RRM_5 PF13893.1 KPI35693.1 - 0.04 13.7 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KPI35694.1 - 6.6e-20 70.5 0.0 3.2e-14 52.3 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI35694.1 - 1.1e-13 50.9 0.0 1.4e-09 37.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI35694.1 - 1.7e-08 34.2 0.0 7.3e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KPI35694.1 - 0.0014 18.3 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 Limkain b1 6PF2K PF01591.13 KPI35696.1 - 7.8e-64 214.7 0.0 7.9e-44 149.3 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KPI35696.1 - 1e-26 93.9 0.2 3e-26 92.4 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KPI35696.1 - 1.5e-06 28.1 0.0 2.7e-05 24.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KPI35696.1 - 0.0013 19.5 0.0 0.0054 17.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KPI35696.1 - 0.069 12.2 0.0 2.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin KTI12 PF08433.5 KPI35696.1 - 0.092 11.9 0.0 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_22 PF13401.1 KPI35696.1 - 0.17 12.0 0.0 0.98 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mito_carr PF00153.22 KPI35697.1 - 1.3e-28 98.5 4.3 2.1e-15 56.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Vwaint PF14624.1 KPI35697.1 - 0.045 13.8 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 VWA / Hh protein intein-like PhoH PF02562.11 KPI35697.1 - 0.59 9.3 3.2 2.2 7.4 0.0 2.2 1 1 1 2 2 2 0 PhoH-like protein PRELI PF04707.9 KPI35698.1 - 8.4e-24 83.9 0.0 4.1e-21 75.1 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family DUF1320 PF07030.7 KPI35699.1 - 0.11 12.1 0.0 2 8.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1320) SWIM PF04434.12 KPI35700.1 - 0.0048 16.3 4.8 0.41 10.1 0.1 2.3 2 0 0 2 2 2 2 SWIM zinc finger Spc97_Spc98 PF04130.8 KPI35701.1 - 1.8e-42 145.3 0.0 2.6e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 KPI35701.1 - 0.005 15.0 4.3 0.039 12.0 2.1 2.5 2 1 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 Nucleo_P87 PF07267.6 KPI35701.1 - 0.21 10.2 0.1 0.33 9.5 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF641 PF04859.7 KPI35703.1 - 0.001 18.8 4.2 0.0024 17.6 2.9 1.6 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) SlyX PF04102.7 KPI35703.1 - 0.014 15.7 3.4 0.062 13.6 2.3 2.2 1 0 0 1 1 1 0 SlyX Borrelia_P83 PF05262.6 KPI35703.1 - 0.065 11.4 1.7 0.1 10.8 1.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein USP8_interact PF08941.5 KPI35703.1 - 0.12 11.7 0.7 0.23 10.7 0.5 1.4 1 0 0 1 1 1 0 USP8 interacting DivIC PF04977.10 KPI35703.1 - 0.53 9.8 4.8 1.3 8.5 3.3 1.7 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 KPI35703.1 - 0.78 9.3 6.0 1.4 8.4 4.1 1.3 1 0 0 1 1 1 0 IncA protein FliD_N PF02465.13 KPI35703.1 - 2 8.8 5.4 1.3 9.4 0.7 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Fungal_trans PF04082.13 KPI35705.1 - 1.8e-11 43.3 0.1 3.5e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Inhibitor_I9 PF05922.11 KPI35706.1 - 0.0032 17.9 0.0 0.0057 17.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF3186 PF11382.3 KPI35706.1 - 0.0098 15.0 1.6 0.82 8.7 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3186) ParA PF10609.4 KPI35706.1 - 0.089 12.6 0.0 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 ParA/MinD ATPase like VHS PF00790.14 KPI35707.1 - 5.9e-42 142.6 0.0 1.6e-41 141.2 0.0 1.8 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 KPI35707.1 - 1.1e-24 86.2 0.4 3.3e-24 84.7 0.3 1.8 1 0 0 1 1 1 1 GAT domain Methyltransf_23 PF13489.1 KPI35707.1 - 3.3e-16 59.4 0.0 7.3e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI35707.1 - 3.9e-09 36.2 0.0 1.8e-07 30.8 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI35707.1 - 1.1e-06 29.0 0.0 4.1e-06 27.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI35707.1 - 3.5e-06 27.5 0.0 2.8e-05 24.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Alpha_adaptinC2 PF02883.15 KPI35707.1 - 1.6e-05 25.2 1.1 1.6e-05 25.2 0.8 1.9 2 0 0 2 2 1 1 Adaptin C-terminal domain Methyltransf_12 PF08242.7 KPI35707.1 - 0.00011 22.5 0.0 0.00045 20.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI35707.1 - 0.00032 21.0 0.0 0.00082 19.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KPI35707.1 - 0.0082 15.2 0.0 0.018 14.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase ChiC PF06483.6 KPI35707.1 - 0.021 14.5 0.2 0.04 13.6 0.1 1.5 1 0 0 1 1 1 0 Chitinase C Methyltransf_2 PF00891.13 KPI35707.1 - 0.037 13.2 0.0 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase FtsJ PF01728.14 KPI35707.1 - 0.06 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 KPI35707.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ras PF00071.17 KPI35708.1 - 1.9e-63 212.6 0.2 2.3e-63 212.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KPI35708.1 - 1.1e-20 74.3 0.1 1.5e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KPI35708.1 - 2.8e-13 49.4 0.0 3.6e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KPI35708.1 - 8.1e-08 32.2 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KPI35708.1 - 3.4e-05 23.3 0.1 0.00011 21.6 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KPI35708.1 - 0.00012 22.2 0.1 0.00031 20.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 KPI35708.1 - 0.00014 21.0 0.1 0.00025 20.2 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 KPI35708.1 - 0.0015 17.6 0.1 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KPI35708.1 - 0.002 18.0 0.1 0.0054 16.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KPI35708.1 - 0.0023 17.1 0.1 0.0052 15.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 KPI35708.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit SpoIIID PF12116.3 KPI35708.1 - 0.016 15.1 0.1 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Stage III sporulation protein D ABC_tran PF00005.22 KPI35708.1 - 0.026 14.8 0.1 0.036 14.3 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 KPI35708.1 - 0.028 14.4 0.3 0.054 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 KPI35708.1 - 0.048 13.2 0.1 0.092 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KPI35708.1 - 0.086 12.3 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 KPI35708.1 - 0.11 11.8 0.1 0.32 10.2 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_5 PF07728.9 KPI35708.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3455 PF11937.3 KPI35709.1 - 1e-11 45.1 0.5 1.1e-05 25.4 0.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3455) Catalase PF00199.14 KPI35711.1 - 1.5e-166 553.8 0.6 2.1e-166 553.3 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KPI35711.1 - 1.6e-13 50.2 0.0 5.7e-13 48.5 0.0 2.0 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF2370 PF10176.4 KPI35712.1 - 0.02 14.2 0.9 0.44 9.8 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2370) adh_short PF00106.20 KPI35713.1 - 2.4e-20 73.1 0.1 3.3e-20 72.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI35713.1 - 2.5e-05 24.0 0.0 3.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI35713.1 - 0.00011 22.0 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CTD_bind PF04818.8 KPI35714.1 - 0.004 17.3 0.0 0.0079 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-ISL3 PF14690.1 KPI35714.1 - 0.053 13.5 0.3 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 VHS PF00790.14 KPI35714.1 - 0.07 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 VHS domain DUF4521 PF15021.1 KPI35714.1 - 0.086 12.4 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4521) CENP-C_C PF11699.3 KPI35717.1 - 6.5e-28 96.5 0.1 1.1e-27 95.8 0.1 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 KPI35717.1 - 1.4e-11 45.1 0.9 1.4e-11 45.1 0.6 3.9 3 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 KPI35717.1 - 2.3e-06 26.9 0.0 5.3e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Rad51 PF08423.6 KPI35718.1 - 5.5e-24 84.4 0.0 7.9e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KPI35718.1 - 3.9e-10 39.4 0.0 6.8e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KPI35718.1 - 1.6e-05 24.1 0.2 0.0021 17.1 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein KaiC PF06745.8 KPI35718.1 - 0.012 14.7 0.0 0.03 13.4 0.0 1.7 2 0 0 2 2 2 0 KaiC Abhydrolase_2 PF02230.11 KPI35719.1 - 3.2e-15 56.1 0.0 4e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KPI35719.1 - 1.3e-06 28.5 0.2 1.8e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI35719.1 - 1.5e-06 28.0 0.1 2.3e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KPI35719.1 - 0.2 11.2 0.7 0.37 10.3 0.5 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold AMP-binding PF00501.23 KPI35720.1 - 1.1e-68 231.5 0.0 1.7e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI35720.1 - 5.6e-11 43.2 0.0 1.2e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC_tran PF00005.22 KPI35721.1 - 3.2e-43 147.3 0.0 3.7e-25 88.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KPI35721.1 - 7.3e-34 117.4 16.2 3e-16 59.6 4.2 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KPI35721.1 - 4.8e-13 48.8 0.5 0.0035 16.6 0.0 4.4 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KPI35721.1 - 1.3e-09 38.4 0.0 0.14 12.1 0.0 4.6 2 2 0 3 3 3 3 AAA domain AAA_23 PF13476.1 KPI35721.1 - 8.6e-06 26.2 0.0 0.096 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KPI35721.1 - 1.1e-05 24.6 0.0 0.012 14.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KPI35721.1 - 1.2e-05 25.4 0.2 0.11 12.6 0.2 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KPI35721.1 - 8e-05 22.0 1.4 0.011 15.2 0.5 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KPI35721.1 - 0.00014 21.2 2.2 0.042 13.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 KPI35721.1 - 0.00018 21.0 0.1 0.022 14.2 0.0 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KPI35721.1 - 0.00031 20.3 0.0 0.047 13.1 0.0 2.8 3 0 0 3 3 2 1 AAA-like domain T2SE PF00437.15 KPI35721.1 - 0.00088 18.2 0.1 0.15 10.9 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KPI35721.1 - 0.0032 17.4 0.0 0.41 10.6 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.12 KPI35721.1 - 0.0051 16.6 0.5 0.0051 16.6 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 KPI35721.1 - 0.0064 15.6 0.8 1.2 8.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 KPI35721.1 - 0.0066 16.1 0.3 0.45 10.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 KPI35721.1 - 0.013 15.3 0.0 1.4 8.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KPI35721.1 - 0.041 14.3 0.1 6.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein cobW PF02492.14 KPI35721.1 - 0.047 13.1 2.6 1.4 8.3 0.2 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KPI35721.1 - 0.065 14.0 0.0 2 9.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KPI35721.1 - 0.067 12.6 0.4 2.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TrwB_AAD_bind PF10412.4 KPI35721.1 - 0.11 11.1 1.9 1.6 7.2 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain UPF0079 PF02367.12 KPI35721.1 - 0.13 11.9 0.8 0.5 10.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_13 PF13166.1 KPI35721.1 - 0.15 10.4 0.0 6.5 5.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain IGPD PF00475.13 KPI35721.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase MobB PF03205.9 KPI35721.1 - 0.17 11.5 1.9 6.9 6.3 0.1 2.7 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KPI35721.1 - 0.23 11.7 0.2 4.1 7.7 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KPI35721.1 - 0.3 11.0 9.2 2.2 8.2 0.0 4.0 4 1 0 4 4 4 0 AAA ATPase domain Dynamin_N PF00350.18 KPI35721.1 - 1.9 8.2 4.2 17 5.1 0.1 2.9 3 0 0 3 3 3 0 Dynamin family Aminotran_4 PF01063.14 KPI35723.1 - 1.3e-23 83.7 0.0 1.6e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV VirC2 PF07181.6 KPI35723.1 - 0.041 13.2 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 VirC2 protein ECH PF00378.15 KPI35724.1 - 1.8e-25 89.5 0.0 2.2e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF3128 PF11326.3 KPI35726.1 - 1.1e-28 99.2 2.0 2.4e-28 98.0 1.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Nsp1_C PF05064.8 KPI35726.1 - 0.024 14.2 1.6 0.043 13.4 0.3 1.8 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF4404 PF14357.1 KPI35726.1 - 0.16 12.4 1.3 3 8.3 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Coagulase PF08764.5 KPI35727.1 - 0.028 14.3 0.2 0.04 13.8 0.1 1.1 1 0 0 1 1 1 0 Staphylococcus aureus coagulase Med1 PF10744.4 KPI35728.1 - 8.6e-07 28.0 0.4 7.1e-06 25.0 0.0 1.9 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 SUR7 PF06687.7 KPI35729.1 - 0.072 12.6 4.1 0.16 11.4 2.8 1.6 1 0 0 1 1 1 0 SUR7/PalI family MitMem_reg PF13012.1 KPI35730.1 - 4e-40 136.4 0.0 7.7e-40 135.5 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KPI35730.1 - 2.4e-24 85.2 0.0 6.8e-24 83.8 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Na_H_Exchanger PF00999.16 KPI35731.1 - 4e-46 157.2 14.6 5.5e-46 156.8 10.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YtpI PF14007.1 KPI35731.1 - 8.9 6.3 7.8 14 5.7 0.0 3.4 4 0 0 4 4 4 0 YtpI-like protein Aldo_ket_red PF00248.16 KPI35732.1 - 8.5e-66 221.6 0.0 1.2e-65 221.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.3 KPI35732.1 - 2.8e-21 75.5 0.0 4.1e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMN_dh PF01070.13 KPI35733.1 - 8.1e-104 347.2 0.0 1.1e-103 346.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KPI35733.1 - 2.7e-18 65.5 0.0 1.5e-17 63.1 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KPI35733.1 - 5.2e-09 35.4 0.0 1.2e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KPI35733.1 - 6.3e-08 31.9 0.2 9.4e-08 31.3 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 KPI35733.1 - 0.0016 17.4 0.3 0.0034 16.3 0.2 1.6 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.10 KPI35733.1 - 0.004 16.3 0.7 0.008 15.3 0.4 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 KPI35733.1 - 0.0074 15.5 0.2 0.02 14.1 0.1 1.7 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 KPI35733.1 - 0.041 12.9 0.1 0.14 11.2 0.1 1.8 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Ribul_P_3_epim PF00834.14 KPI35733.1 - 0.057 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Clr5 PF14420.1 KPI35734.1 - 1.6e-15 56.7 2.1 3.2e-15 55.7 1.4 1.5 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 KPI35734.1 - 3e-06 27.0 0.5 1.1 9.2 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KPI35734.1 - 0.0011 19.6 2.6 1.6 9.4 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KPI35734.1 - 0.0025 17.5 0.2 2 8.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KPI35734.1 - 0.058 13.0 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 TPR repeat TPR_10 PF13374.1 KPI35734.1 - 0.06 13.2 3.2 3.5 7.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat ACOX PF01756.14 KPI35734.1 - 0.1 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA oxidase p450 PF00067.17 KPI35735.1 - 1.1e-68 231.9 0.0 1.4e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WLM PF08325.5 KPI35736.1 - 1.4e-43 148.8 0.0 2.5e-43 148.1 0.0 1.4 1 1 0 1 1 1 1 WLM domain SprT-like PF10263.4 KPI35736.1 - 0.016 14.8 0.2 0.033 13.8 0.2 1.5 1 0 0 1 1 1 0 SprT-like family eIF3_p135 PF12807.2 KPI35736.1 - 0.023 14.6 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 DUF45 PF01863.12 KPI35736.1 - 0.028 14.1 1.0 0.06 13.1 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF45 SH2_2 PF14633.1 KPI35737.1 - 6.6e-77 257.5 0.1 8.1e-77 257.2 0.0 1.1 1 0 0 1 1 1 1 SH2 domain SH2 PF00017.19 KPI35737.1 - 0.00019 21.1 0.0 0.00053 19.7 0.0 1.8 2 0 0 2 2 2 1 SH2 domain YwhD PF08741.5 KPI35737.1 - 0.094 12.1 0.1 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 YwhD family DUF4080 PF13311.1 KPI35737.1 - 0.12 12.4 2.7 0.39 10.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) tRNA-synt_1b PF00579.20 KPI35738.1 - 1.6e-12 47.1 0.0 4.5e-12 45.7 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Hid1 PF12722.2 KPI35738.1 - 2.5 5.6 11.7 3.1 5.3 8.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3759 PF12585.3 KPI35739.1 - 4.1e-38 129.1 5.4 7.1e-38 128.4 3.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) HET PF06985.6 KPI35740.1 - 1.4e-32 112.7 1.2 2.2e-32 112.1 0.8 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Bac_rhamnosid PF05592.6 KPI35740.1 - 0.071 11.3 0.1 0.11 10.7 0.1 1.1 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase Fungal_trans PF04082.13 KPI35741.1 - 1.2e-10 40.7 0.1 1.8e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3425 PF11905.3 KPI35742.1 - 8.5e-19 67.7 0.6 1.9e-18 66.6 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KPI35742.1 - 0.0048 16.8 3.9 0.014 15.3 2.7 1.8 1 1 0 1 1 1 1 bZIP transcription factor CorA PF01544.13 KPI35743.1 - 1.2e-15 57.3 0.7 2.8e-15 56.1 0.4 1.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein 7TM_GPCR_Srab PF10292.4 KPI35743.1 - 0.0017 17.1 0.2 0.0027 16.4 0.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor DUF2207 PF09972.4 KPI35743.1 - 0.023 13.3 0.3 0.03 12.9 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF155 PF02582.9 KPI35743.1 - 0.064 13.1 0.2 0.096 12.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Prefoldin_2 PF01920.15 KPI35743.1 - 0.1 12.3 2.8 0.18 11.5 1.9 1.4 1 0 0 1 1 1 0 Prefoldin subunit Fumarate_red_C PF02300.12 KPI35743.1 - 0.11 12.4 0.4 0.2 11.5 0.3 1.4 1 0 0 1 1 1 0 Fumarate reductase subunit C DUF2115 PF09888.4 KPI35743.1 - 0.16 12.0 2.0 0.17 12.0 0.4 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) DUF2721 PF11026.3 KPI35743.1 - 0.82 9.3 5.9 0.61 9.7 2.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) DUF427 PF04248.7 KPI35744.1 - 2.8e-30 103.8 0.1 8.6e-25 86.2 0.0 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF427) DUF221 PF02714.10 KPI35745.1 - 5.1e-72 242.4 23.0 4.4e-63 213.1 8.9 3.2 2 1 1 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 KPI35745.1 - 4.6e-38 130.2 0.3 4.6e-38 130.2 0.2 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KPI35745.1 - 3.1e-15 55.8 0.0 1.4e-14 53.7 0.0 2.0 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 KPI35745.1 - 4.6e-08 33.4 0.0 8.9e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_5 PF13893.1 KPI35745.1 - 0.17 11.7 0.1 0.45 10.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_3 PF01494.14 KPI35746.1 - 4e-46 157.7 0.0 5.5e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI35746.1 - 4.3e-07 29.1 0.0 0.0015 17.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI35746.1 - 1.8e-05 23.7 0.2 0.00028 19.8 0.2 2.1 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KPI35746.1 - 2.8e-05 24.0 0.1 7e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KPI35746.1 - 3.3e-05 22.5 0.0 6.4e-05 21.6 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 KPI35746.1 - 0.0001 21.3 0.0 0.00026 20.0 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KPI35746.1 - 0.00046 19.3 0.0 0.00074 18.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KPI35746.1 - 0.00052 19.9 0.1 0.0013 18.6 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KPI35746.1 - 0.0025 16.9 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KPI35746.1 - 0.0032 16.3 0.0 0.0043 15.9 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KPI35746.1 - 0.0053 16.8 0.1 0.023 14.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI35746.1 - 0.015 15.7 0.0 0.035 14.5 0.0 1.6 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KPI35746.1 - 0.04 12.5 0.1 0.078 11.5 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase ApbA PF02558.11 KPI35746.1 - 0.043 13.2 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 KPI35746.1 - 0.048 13.4 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KPI35746.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cyclin PF08613.6 KPI35747.1 - 8.7e-29 100.8 2.9 2.8e-28 99.1 2.0 2.2 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KPI35747.1 - 0.00055 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DLD PF14878.1 KPI35748.1 - 6.7e-35 119.6 5.5 6.7e-35 119.6 3.8 3.5 4 0 0 4 4 4 1 Death-like domain of SPT6 HHH_7 PF14635.1 KPI35748.1 - 7.6e-26 90.2 0.0 1.4e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 KPI35748.1 - 9.4e-22 77.2 0.3 4.3e-21 75.1 0.2 2.2 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.1 KPI35748.1 - 2.8e-21 75.6 0.0 1.6e-20 73.1 0.0 2.3 1 1 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 KPI35748.1 - 5e-17 61.8 32.3 5e-17 61.8 22.4 4.2 5 0 0 5 5 5 1 Acidic N-terminal SPT6 FHA PF00498.21 KPI35749.1 - 4.6e-14 52.2 0.0 9e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain Sugar_tr PF00083.19 KPI35750.1 - 1.6e-84 284.1 20.8 1.8e-84 283.8 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI35750.1 - 7.7e-13 47.8 44.7 1.8e-08 33.4 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AIRC PF00731.15 KPI35751.1 - 0.019 14.2 1.5 0.047 12.9 0.1 2.4 2 1 0 2 2 2 0 AIR carboxylase Imm42 PF15601.1 KPI35751.1 - 0.069 12.5 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 42 CAP_GLY PF01302.20 KPI35752.1 - 2.7e-14 52.6 6.4 9.1e-11 41.3 1.6 2.3 1 1 1 2 2 2 2 CAP-Gly domain Ubiquitin_2 PF14560.1 KPI35752.1 - 5.8e-12 45.6 0.0 1.2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 KPI35752.1 - 0.00027 20.2 0.0 0.00059 19.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family IncA PF04156.9 KPI35754.1 - 0.15 11.6 8.0 2.2 7.8 0.2 2.3 2 0 0 2 2 2 0 IncA protein DUF904 PF06005.7 KPI35754.1 - 3.1 8.1 7.7 0.25 11.6 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Glyco_hydro_17 PF00332.13 KPI35755.1 - 2.8e-05 23.3 0.4 7.1e-05 21.9 0.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 JmjC PF02373.17 KPI35755.1 - 0.052 13.7 0.1 0.54 10.5 0.0 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase Pkinase PF00069.20 KPI35756.1 - 1.3e-74 250.6 0.0 1.9e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI35756.1 - 2.1e-38 131.9 0.0 3.3e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 KPI35756.1 - 6e-16 58.3 0.3 2.8e-15 56.1 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 KPI35756.1 - 2.6e-06 26.5 0.0 6.6e-06 25.3 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 KPI35756.1 - 0.0052 15.8 0.1 0.0099 14.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.4 KPI35756.1 - 0.012 14.2 0.2 0.019 13.5 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC RNase_HII PF01351.13 KPI35757.1 - 8.6e-50 169.1 0.0 1.1e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII CoA_transf_3 PF02515.12 KPI35760.1 - 3.6e-52 176.3 0.0 5.2e-52 175.8 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III HOOK PF05622.7 KPI35761.1 - 4.2e-20 71.1 57.1 3.8e-16 58.1 37.5 4.5 1 1 1 2 2 2 2 HOOK protein Reo_sigmaC PF04582.7 KPI35761.1 - 0.028 13.6 6.1 0.065 12.4 0.5 2.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Flu_M1_C PF08289.6 KPI35761.1 - 0.059 13.4 0.3 0.059 13.4 0.2 2.4 2 1 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain TMEM192 PF14802.1 KPI35761.1 - 1.9 7.2 4.8 0.32 9.8 0.4 1.9 2 0 0 2 2 2 0 TMEM192 family Pkinase PF00069.20 KPI35762.1 - 2.8e-59 200.3 0.0 4e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI35762.1 - 4.4e-33 114.4 0.0 6.4e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI35762.1 - 0.00011 21.2 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KPI35762.1 - 0.021 13.6 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 KPI35762.1 - 0.087 12.5 0.0 0.59 9.8 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family TPR_11 PF13414.1 KPI35763.1 - 1.8e-51 171.6 13.1 7.1e-14 51.2 0.0 6.5 3 1 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 KPI35763.1 - 6.7e-40 133.1 19.9 4.6e-06 25.9 0.0 10.7 9 1 1 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 KPI35763.1 - 7e-36 119.2 16.0 7.9e-05 22.2 0.0 10.8 9 1 1 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 KPI35763.1 - 9.1e-25 86.7 5.3 2.8e-06 27.8 0.3 6.0 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 KPI35763.1 - 9.2e-22 76.7 21.0 1.7e-07 31.0 0.2 6.9 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 KPI35763.1 - 9.2e-20 69.1 6.9 0.00076 19.4 0.0 7.7 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KPI35763.1 - 8.4e-18 62.7 15.6 0.013 15.2 0.2 9.5 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 KPI35763.1 - 5.3e-15 54.5 17.0 0.024 15.2 0.2 9.6 3 3 7 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 KPI35763.1 - 9.2e-15 53.2 16.3 0.063 13.1 0.1 8.4 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 KPI35763.1 - 8e-13 48.5 23.6 0.00035 20.8 1.0 6.8 5 1 2 8 8 7 4 Tetratricopeptide repeat Apc3 PF12895.2 KPI35763.1 - 2.3e-10 40.4 15.7 0.034 14.2 0.2 5.4 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KPI35763.1 - 2.7e-09 36.7 13.0 0.00069 19.4 0.3 6.2 3 1 2 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 KPI35763.1 - 2.3e-08 33.4 6.4 0.31 10.0 0.7 5.3 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_6 PF13174.1 KPI35763.1 - 2.2e-05 24.5 22.8 2.6 8.7 0.0 8.6 9 0 0 9 9 8 1 Tetratricopeptide repeat MAS20 PF02064.10 KPI35763.1 - 0.0017 18.2 3.0 1 9.3 0.0 4.5 6 0 0 6 6 5 1 MAS20 protein import receptor NARP1 PF12569.3 KPI35763.1 - 0.0027 16.5 0.2 0.0027 16.5 0.2 3.9 1 1 2 4 4 3 2 NMDA receptor-regulated protein 1 TPR_10 PF13374.1 KPI35763.1 - 0.0069 16.2 5.7 9.2 6.3 0.2 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 KPI35763.1 - 0.058 13.2 13.1 0.69 9.7 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Sel1 PF08238.7 KPI35763.1 - 0.11 13.1 7.7 5.5 7.7 0.0 4.7 4 0 0 4 4 3 0 Sel1 repeat Apc5 PF12862.2 KPI35763.1 - 0.26 11.1 9.2 4.5 7.1 0.2 4.6 4 1 1 5 5 4 0 Anaphase-promoting complex subunit 5 SHNi-TPR PF10516.4 KPI35763.1 - 0.3 10.3 24.4 1.5 8.1 0.1 7.3 8 0 0 8 8 7 0 SHNi-TPR TPR_20 PF14561.1 KPI35763.1 - 1.4 9.0 9.6 6.9 6.8 0.4 4.7 4 1 1 5 5 4 0 Tetratricopeptide repeat MIT PF04212.13 KPI35763.1 - 4.7 7.1 12.5 16 5.4 0.2 5.1 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain AMP-binding PF00501.23 KPI35764.1 - 3.4e-67 226.6 0.0 4.5e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI35764.1 - 7e-13 49.3 0.5 2.3e-12 47.7 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain F-box-like PF12937.2 KPI35765.1 - 0.069 12.8 0.9 0.25 11.0 0.6 1.9 1 1 0 1 1 1 0 F-box-like DUF4137 PF13593.1 KPI35766.1 - 2e-72 243.9 25.5 2.2e-72 243.7 17.7 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 KPI35766.1 - 1.5e-09 37.4 7.4 1.5e-09 37.4 5.2 2.5 1 1 1 2 2 2 2 Sodium Bile acid symporter family Med1 PF10744.4 KPI35767.1 - 3.2e-20 72.2 0.1 4.9e-20 71.6 0.1 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 SseC PF04888.7 KPI35768.1 - 0.016 14.5 0.9 0.03 13.6 0.6 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Aldolase_II PF00596.16 KPI35769.1 - 2.4e-46 157.6 0.1 3.2e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF360 PF04020.8 KPI35770.1 - 0.72 10.2 15.9 0.055 13.8 0.6 2.8 3 0 0 3 3 3 0 Membrane protein of unknown function Abhydrolase_9_N PF15420.1 KPI35770.1 - 1.9 8.2 7.5 0.12 12.1 0.6 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DAO PF01266.19 KPI35771.1 - 1.9e-42 145.4 1.4 2.6e-42 144.9 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 KPI35771.1 - 0.00096 18.3 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_9 PF13454.1 KPI35771.1 - 0.025 14.3 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KPI35771.1 - 0.026 14.6 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 KPI35773.1 - 6.3e-08 32.7 1.0 5.1e-07 29.7 0.2 2.5 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KPI35773.1 - 0.015 14.9 0.5 0.19 11.3 0.0 2.4 3 0 0 3 3 3 0 KR domain Gar1 PF04410.9 KPI35774.1 - 5.9e-41 139.4 0.0 1.2e-40 138.4 0.0 1.5 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Acyl-CoA_dh_1 PF00441.19 KPI35776.1 - 7.5e-34 117.0 1.3 1.2e-33 116.3 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KPI35776.1 - 7.8e-18 65.1 0.0 1.9e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KPI35776.1 - 5.8e-17 62.1 0.2 5.8e-17 62.1 0.2 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KPI35776.1 - 3.4e-13 48.8 0.1 7e-13 47.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain FlxA PF14282.1 KPI35777.1 - 0.088 12.7 0.1 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 FlxA-like protein Muted PF14942.1 KPI35777.1 - 0.091 12.6 0.2 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein PPR PF01535.15 KPI35777.1 - 0.13 12.3 0.1 0.59 10.2 0.0 2.1 2 0 0 2 2 2 0 PPR repeat ECH PF00378.15 KPI35778.1 - 3e-39 134.6 0.0 5.4e-39 133.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KPI35778.1 - 0.016 14.9 0.2 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 ADH_zinc_N PF00107.21 KPI35779.1 - 2.9e-26 91.5 0.3 4.6e-26 90.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI35779.1 - 7.9e-24 83.5 2.6 7.9e-24 83.5 1.8 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KPI35779.1 - 6.3e-05 23.8 0.2 0.00013 22.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ribonucleas_3_3 PF14622.1 KPI35780.1 - 0.00041 20.3 0.5 0.15 11.9 0.0 3.1 2 1 1 3 3 3 1 Ribonuclease-III-like EMP24_GP25L PF01105.19 KPI35780.1 - 0.0005 19.8 0.4 0.00077 19.2 0.3 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DSHCT PF08148.7 KPI35780.1 - 0.065 12.4 0.6 0.12 11.5 0.1 1.6 2 0 0 2 2 2 0 DSHCT (NUC185) domain Syntaxin-6_N PF09177.6 KPI35780.1 - 0.071 13.5 1.8 0.14 12.5 1.3 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Ribonuclease_3 PF00636.21 KPI35780.1 - 0.089 13.2 1.4 22 5.5 0.0 3.0 3 0 0 3 3 3 0 Ribonuclease III domain TOM20_plant PF06552.7 KPI35780.1 - 0.11 12.1 1.2 0.16 11.5 0.8 1.2 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 DUF4407 PF14362.1 KPI35780.1 - 0.12 11.2 3.7 0.77 8.6 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3573 PF12097.3 KPI35780.1 - 0.14 10.7 0.4 0.19 10.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) ADH_zinc_N_2 PF13602.1 KPI35781.1 - 5.7e-17 62.7 0.0 1.1e-16 61.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KPI35781.1 - 6.9e-12 45.0 0.0 4.9e-11 42.3 0.0 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI35781.1 - 0.0039 16.9 0.0 0.0097 15.6 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Pyr_redox_3 PF13738.1 KPI35782.1 - 6.9e-20 71.9 0.0 2.9e-18 66.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI35782.1 - 2.6e-17 62.2 0.7 1.3e-16 59.9 0.3 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI35782.1 - 1e-07 31.8 0.0 3.4e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI35782.1 - 0.00014 20.9 0.0 0.014 14.3 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KPI35782.1 - 0.0028 17.4 0.0 0.18 11.6 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KPI35782.1 - 0.036 13.1 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 KPI35782.1 - 0.37 11.2 0.0 0.37 11.2 0.0 2.6 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Pyridox_oxidase PF01243.15 KPI35783.1 - 1.1e-06 28.6 0.0 2.9e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.7 KPI35783.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative FMN-binding domain FAD_binding_3 PF01494.14 KPI35784.1 - 1.7e-17 63.5 0.3 3.7e-09 36.0 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KPI35784.1 - 2.4e-10 39.8 0.3 1.8e-06 27.1 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KPI35784.1 - 1.8e-07 30.6 0.1 0.0015 17.6 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KPI35784.1 - 1e-06 28.6 0.1 2.1e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI35784.1 - 1.4e-05 25.0 0.2 8.8e-05 22.4 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI35784.1 - 4.3e-05 22.5 0.5 0.0026 16.6 0.4 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KPI35784.1 - 0.00017 20.6 0.0 0.00029 19.8 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KPI35784.1 - 0.00017 20.1 0.1 0.012 14.1 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KPI35784.1 - 0.00067 18.6 0.8 0.001 18.0 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Rossmann-like PF10727.4 KPI35784.1 - 0.00079 19.1 0.1 0.0015 18.2 0.1 1.5 1 0 0 1 1 1 1 Rossmann-like domain AlaDh_PNT_C PF01262.16 KPI35784.1 - 0.0016 18.0 0.1 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KPI35784.1 - 0.0026 17.8 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KPI35784.1 - 0.0035 16.0 0.5 0.16 10.5 0.2 2.7 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_2 PF03446.10 KPI35784.1 - 0.0052 16.6 0.1 0.027 14.3 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_9 PF13454.1 KPI35784.1 - 0.0057 16.4 0.1 0.2 11.4 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KPI35784.1 - 0.011 15.3 0.1 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KPI35784.1 - 0.012 15.9 0.2 0.048 14.0 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KPI35784.1 - 0.014 14.2 0.0 0.05 12.4 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase ApbA PF02558.11 KPI35784.1 - 0.016 14.6 0.2 0.033 13.6 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 KPI35784.1 - 0.083 11.9 0.1 0.18 10.8 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pro_CA PF00484.14 KPI35785.1 - 1.2e-11 44.7 0.0 1.8e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase AIM24 PF01987.12 KPI35786.1 - 3.8e-52 176.8 0.0 5.2e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Aph-1 PF06105.7 KPI35786.1 - 0.06 12.5 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Aph-1 protein Dyp_perox PF04261.7 KPI35787.1 - 2e-08 33.3 0.0 4.1e-07 29.0 0.0 2.5 2 1 0 2 2 2 2 Dyp-type peroxidase family Zn_clus PF00172.13 KPI35788.1 - 0.00021 21.1 2.4 0.00021 21.1 1.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KPI35788.1 - 0.0017 17.0 0.3 0.0017 17.0 0.2 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain DUF3301 PF11743.3 KPI35788.1 - 0.26 10.8 2.8 0.88 9.1 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) MARVEL PF01284.18 KPI35789.1 - 9.3e-23 80.6 16.4 1.1e-22 80.3 11.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain Glyoxalase PF00903.20 KPI35790.1 - 3.1e-10 40.1 5.1 2.5e-08 33.9 0.9 2.8 3 0 0 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KPI35790.1 - 1.1e-06 29.2 0.2 0.0069 16.9 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KPI35790.1 - 0.0042 17.0 0.9 0.2 11.6 0.3 3.0 2 1 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Cyclase PF04199.8 KPI35791.1 - 8.3e-11 41.8 0.0 1.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase EB_dh PF09459.5 KPI35791.1 - 0.0055 16.1 0.4 0.0075 15.7 0.3 1.2 1 0 0 1 1 1 1 Ethylbenzene dehydrogenase Histone PF00125.19 KPI35792.1 - 2.2e-31 107.8 0.4 3.2e-31 107.2 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KPI35792.1 - 4.5e-06 26.7 0.0 7.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KPI35792.1 - 0.0069 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KPI35792.1 - 0.054 13.2 0.1 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated CPL PF08144.6 KPI35793.1 - 1.2e-14 54.4 0.3 3.4e-13 49.6 0.0 2.7 1 1 1 2 2 2 1 CPL (NUC119) domain Ribosomal_L32p PF01783.18 KPI35794.1 - 2.2e-14 53.3 5.9 3.1e-14 52.8 4.1 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family DZR PF12773.2 KPI35794.1 - 0.011 15.5 0.6 0.017 14.8 0.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon PolC_DP2 PF03833.8 KPI35794.1 - 0.012 13.3 0.4 0.013 13.1 0.3 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-Mss51 PF13824.1 KPI35794.1 - 0.059 13.2 1.5 0.11 12.3 1.1 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn-ribbon_8 PF09723.5 KPI35794.1 - 0.1 12.5 1.4 0.52 10.3 0.1 2.1 1 1 1 2 2 2 0 Zinc ribbon domain DUF1477 PF07346.6 KPI35794.1 - 0.11 12.5 0.1 0.15 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) Atg14 PF10186.4 KPI35794.1 - 0.2 10.5 2.7 0.19 10.6 0.6 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 PhnA_Zn_Ribbon PF08274.7 KPI35794.1 - 0.27 11.0 1.4 2.5 7.9 0.0 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-ribbon_3 PF13248.1 KPI35794.1 - 0.93 8.7 7.2 2.1 7.6 5.0 1.6 1 1 0 1 1 1 0 zinc-ribbon domain INCENP_ARK-bind PF03941.10 KPI35796.1 - 6.7e-18 64.2 2.3 3.7e-17 61.9 1.6 2.4 1 1 0 1 1 1 1 Inner centromere protein, ARK binding region Anophelin PF10731.4 KPI35796.1 - 0.49 10.5 10.5 0.3 11.2 0.5 3.2 3 0 0 3 3 3 0 Thrombin inhibitor from mosquito Claudin_2 PF13903.1 KPI35797.1 - 4.1e-05 23.3 0.1 0.0065 16.1 0.3 2.3 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 KPI35797.1 - 0.021 14.3 0.0 0.58 9.6 0.0 2.2 1 1 0 1 1 1 0 SUR7/PalI family Amastin PF07344.6 KPI35797.1 - 0.026 14.1 0.1 0.52 9.9 0.0 2.2 2 0 0 2 2 2 0 Amastin surface glycoprotein Claudin_3 PF06653.6 KPI35797.1 - 0.084 12.6 2.7 0.89 9.2 0.1 2.9 3 0 0 3 3 3 0 Tight junction protein, Claudin-like DUF2776 PF10951.3 KPI35797.1 - 0.1 11.6 0.1 0.1 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2776) GSG-1 PF07803.6 KPI35797.1 - 0.28 10.7 2.2 0.66 9.5 1.2 1.9 1 1 1 2 2 2 0 GSG1-like protein Tic20 PF09685.5 KPI35797.1 - 2.2 8.2 10.8 11 6.0 2.0 3.2 3 0 0 3 3 3 0 Tic20-like protein Herpes_US9 PF06072.6 KPI35797.1 - 3.5 7.5 0.0 3.5 7.5 0.0 3.1 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 COG7 PF10191.4 KPI35798.1 - 0.036 11.9 0.0 2.8 5.7 0.0 2.0 2 0 0 2 2 2 0 Golgi complex component 7 (COG7) adh_short PF00106.20 KPI35799.1 - 9e-09 35.4 0.0 2.9e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI35799.1 - 1.2e-06 28.3 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KPI35799.1 - 0.04 14.0 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase eIF-5_eIF-2B PF01873.12 KPI35800.1 - 1.3e-45 154.1 0.2 2e-45 153.4 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Arc_trans_TRASH PF08394.5 KPI35800.1 - 2.6 8.2 7.4 2 8.6 0.2 2.9 2 1 1 3 3 3 0 Archaeal TRASH domain zf-HYPF PF07503.7 KPI35800.1 - 5 6.6 6.6 29 4.1 3.1 2.7 2 1 1 3 3 3 0 HypF finger PARP PF00644.15 KPI35801.1 - 4.3e-14 52.4 0.0 8.3e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 KPI35801.1 - 1.3e-06 27.8 0.0 3.2e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KPI35801.1 - 0.0089 15.7 0.0 0.035 13.8 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic E2 family B TAT_signal PF10518.4 KPI35803.1 - 0.33 11.0 2.8 0.72 10.0 2.0 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence FAA_hydrolase PF01557.13 KPI35804.1 - 1.1e-50 172.1 0.0 1.6e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family UCH PF00443.24 KPI35806.1 - 1.9e-07 30.5 0.0 3.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GATA PF00320.22 KPI35806.1 - 0.34 10.3 13.5 0.34 10.2 3.6 3.2 2 0 0 2 2 2 0 GATA zinc finger Piwi PF02171.12 KPI35807.1 - 6.8e-47 159.8 0.0 1.1e-46 159.1 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KPI35807.1 - 0.051 12.9 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1785) NARP1 PF12569.3 KPI35807.1 - 5.2 5.7 11.7 8.1 5.0 8.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Mpv17_PMP22 PF04117.7 KPI35808.1 - 1.1e-16 60.1 1.7 1.6e-16 59.6 0.1 2.1 1 1 2 3 3 3 1 Mpv17 / PMP22 family DUF4500 PF14937.1 KPI35808.1 - 0.11 12.4 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) Acetyltransf_1 PF00583.19 KPI35809.1 - 1.3e-08 34.7 0.0 2.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI35809.1 - 0.00035 20.6 0.0 0.00097 19.2 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KPI35809.1 - 0.0043 16.8 0.0 0.0094 15.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI35809.1 - 0.011 15.8 0.2 0.1 12.7 0.0 2.1 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Mito_carr PF00153.22 KPI35810.1 - 1.1e-61 204.5 4.5 1.2e-20 72.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cyclase PF04199.8 KPI35812.1 - 1.6e-14 53.9 0.0 2.7e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase MFS_1 PF07690.11 KPI35813.1 - 4.7e-24 84.7 19.3 5.4e-20 71.4 13.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Lysis_S PF04971.7 KPI35813.1 - 0.02 14.5 0.2 6.8 6.4 0.1 2.9 2 0 0 2 2 2 0 Lysis protein S PITH PF06201.8 KPI35814.1 - 4.7e-46 156.3 0.0 5.8e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 PITH domain UBA_4 PF14555.1 KPI35814.1 - 0.043 13.3 0.1 0.17 11.4 0.1 1.9 2 0 0 2 2 2 0 UBA-like domain Septin PF00735.13 KPI35815.1 - 6.9e-113 376.3 0.4 8.1e-113 376.1 0.3 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KPI35815.1 - 4.6e-07 29.7 0.0 8.2e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KPI35815.1 - 2.6e-06 26.6 0.0 4.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 KPI35815.1 - 4.1e-06 26.3 0.2 0.00058 19.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KPI35815.1 - 4.8e-06 25.8 0.0 8.1e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KPI35815.1 - 0.00033 20.5 0.8 0.43 10.3 0.1 2.5 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 KPI35815.1 - 0.0068 15.8 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 KPI35815.1 - 0.0073 16.6 0.0 0.011 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KPI35815.1 - 0.0091 16.1 0.0 0.019 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KPI35815.1 - 0.0096 15.9 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 KPI35815.1 - 0.016 15.4 0.4 0.036 14.3 0.1 1.7 1 1 0 1 1 1 0 ABC transporter T2SE PF00437.15 KPI35815.1 - 0.036 12.9 0.0 0.076 11.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Ras PF00071.17 KPI35815.1 - 0.049 13.0 0.0 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 Ras family NB-ARC PF00931.17 KPI35815.1 - 0.055 12.3 0.0 0.086 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Miro PF08477.8 KPI35815.1 - 0.059 13.8 0.0 0.18 12.3 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 KPI35815.1 - 0.078 12.4 0.1 0.17 11.2 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 KPI35815.1 - 0.27 12.0 1.5 2.9 8.7 1.0 2.3 1 1 0 1 1 1 0 AAA domain CDC45 PF02724.9 KPI35816.1 - 5.2e-222 738.2 2.8 2.7e-221 735.9 2.0 2.6 1 1 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.7 KPI35816.1 - 0.0074 16.0 12.0 0.0074 16.0 8.3 2.6 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 KPI35816.1 - 1.3 8.2 35.0 0.41 9.8 8.1 2.3 2 0 0 2 2 2 0 SDA1 DUF1510 PF07423.6 KPI35816.1 - 5.2 6.3 31.8 2.2 7.5 9.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 KPI35816.1 - 7.2 5.5 43.1 5.2 6.0 11.8 2.2 2 0 0 2 2 2 0 BUD22 NACHT PF05729.7 KPI35818.1 - 6.6e-05 22.6 0.0 0.00048 19.8 0.0 2.3 1 1 0 1 1 1 1 NACHT domain Ank_4 PF13637.1 KPI35818.1 - 0.00015 22.2 0.1 0.0054 17.2 0.0 2.9 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KPI35818.1 - 0.00034 20.8 0.4 0.027 14.8 0.3 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_22 PF13401.1 KPI35818.1 - 0.0042 17.2 0.0 0.016 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KPI35818.1 - 0.0044 15.9 0.0 0.31 9.8 0.0 3.2 4 0 0 4 4 4 1 NB-ARC domain Tom22 PF04281.8 KPI35818.1 - 0.017 14.6 1.7 0.074 12.5 0.4 2.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Ank PF00023.25 KPI35818.1 - 0.022 14.5 0.0 0.29 11.0 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeat RNA_helicase PF00910.17 KPI35818.1 - 0.17 12.0 0.0 0.45 10.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zn_clus PF00172.13 KPI35819.1 - 1.5e-08 34.3 9.7 1.5e-08 34.3 6.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KPI35819.1 - 0.0045 15.6 0.1 0.013 14.0 0.1 1.7 1 1 0 2 2 2 1 Fungal specific transcription factor domain Exo5 PF09810.4 KPI35821.1 - 7.6e-118 393.4 0.0 9.2e-118 393.1 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 KPI35821.1 - 2.1e-07 30.6 0.2 0.021 14.2 0.1 2.7 1 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily HTH_18 PF12833.2 KPI35821.1 - 0.023 14.7 0.1 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MFS_1 PF07690.11 KPI35822.1 - 1.2e-38 132.8 46.3 1.4e-38 132.5 29.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI35822.1 - 5.1e-08 31.9 28.4 7.8e-08 31.3 18.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter PAP2 PF01569.16 KPI35822.1 - 6.3 6.4 25.0 0.37 10.4 5.6 3.4 2 2 0 2 2 2 0 PAP2 superfamily Dabb PF07876.7 KPI35823.1 - 1e-18 67.5 0.0 1.1e-18 67.4 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Aldose_epim PF01263.15 KPI35826.1 - 3.4e-62 210.2 0.2 4.1e-62 210.0 0.2 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase AAA_13 PF13166.1 KPI35827.1 - 0.72 8.2 35.9 0.4 9.0 5.7 5.4 5 1 2 7 7 7 0 AAA domain Fasciclin PF02469.17 KPI35828.1 - 1.6e-17 63.7 0.0 1.9e-10 40.8 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain SKG6 PF08693.5 KPI35828.1 - 0.00079 18.6 0.3 0.0015 17.7 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MFS_1 PF07690.11 KPI35829.1 - 3.8e-35 121.2 14.0 3.8e-35 121.2 9.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Ribosomal_L27e PF01777.13 KPI35830.1 - 2.9e-38 129.8 5.1 3.7e-38 129.5 3.5 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KPI35830.1 - 0.0051 16.4 0.4 0.0051 16.4 0.3 2.0 2 1 0 2 2 2 1 KOW motif CDC45 PF02724.9 KPI35831.1 - 4.7 5.1 7.2 5.6 4.8 5.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Mpv17_PMP22 PF04117.7 KPI35832.1 - 8e-18 63.8 2.0 8e-18 63.8 1.4 1.9 2 1 0 2 2 2 1 Mpv17 / PMP22 family UQ_con PF00179.21 KPI35833.1 - 1e-41 141.6 0.0 1.1e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Guanylate_kin PF00625.16 KPI35834.1 - 1.8e-55 187.2 0.0 2.4e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 KPI35834.1 - 2e-07 31.0 0.1 0.0002 21.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KPI35834.1 - 8e-06 26.0 0.2 8.2e-05 22.7 0.0 2.3 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KPI35834.1 - 8.8e-05 22.5 0.0 0.00013 22.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 KPI35834.1 - 0.00019 21.7 0.6 0.00097 19.4 0.1 2.3 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 KPI35834.1 - 0.00025 20.2 0.0 0.00052 19.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KPI35834.1 - 0.00082 20.1 0.3 0.0016 19.2 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KPI35834.1 - 0.0015 18.4 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KPI35834.1 - 0.0017 18.5 0.1 0.0081 16.3 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KPI35834.1 - 0.004 17.4 0.1 0.0099 16.1 0.1 1.9 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 KPI35834.1 - 0.0071 15.8 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 KPI35834.1 - 0.0074 16.4 0.0 0.023 14.8 0.0 1.9 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.1 KPI35834.1 - 0.0096 15.5 0.0 0.69 9.4 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 KPI35834.1 - 0.017 15.0 0.0 0.057 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KPI35834.1 - 0.023 14.4 0.3 0.88 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 KPI35834.1 - 0.025 14.5 0.0 0.055 13.4 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 KPI35834.1 - 0.027 14.8 0.5 0.35 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KPI35834.1 - 0.042 13.2 0.0 0.12 11.7 0.0 1.7 2 1 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 KPI35834.1 - 0.043 13.5 0.0 0.47 10.1 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase Miro PF08477.8 KPI35834.1 - 0.052 14.0 0.1 0.13 12.7 0.0 1.8 2 1 0 2 2 1 0 Miro-like protein MobB PF03205.9 KPI35834.1 - 0.059 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KPI35834.1 - 0.083 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.10 KPI35834.1 - 0.087 11.4 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KPI35834.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain MFS_1 PF07690.11 KPI35836.1 - 1.3e-33 116.1 30.8 1.3e-33 116.1 21.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 KPI35837.1 - 1.4e-35 122.6 23.8 1.4e-35 122.6 16.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1191 PF06697.7 KPI35838.1 - 3.7e-05 22.6 0.0 5.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) SKG6 PF08693.5 KPI35838.1 - 0.0024 17.1 0.2 0.0046 16.2 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.1 KPI35838.1 - 0.0047 16.6 1.4 0.0055 16.4 0.0 1.7 2 0 0 2 2 2 1 Transmembrane protein 51 Herpes_gE PF02480.11 KPI35838.1 - 0.053 11.7 0.0 0.081 11.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KPI35838.1 - 0.061 13.7 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PIRT PF15099.1 KPI35838.1 - 0.1 11.8 0.3 0.18 11.0 0.2 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family stn_TNFRSF12A PF12191.3 KPI35838.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF912 PF06024.7 KPI35838.1 - 0.18 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Lactonase PF10282.4 KPI35839.1 - 3e-60 204.1 0.0 3.7e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Oxidored_molyb PF00174.14 KPI35841.1 - 9.6e-45 152.0 0.0 1.8e-44 151.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KPI35841.1 - 1e-32 112.5 0.0 2.4e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.19 KPI35841.1 - 4.3e-18 65.2 0.0 1e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KPI35841.1 - 7.5e-18 65.0 0.0 2.8e-17 63.2 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 KPI35841.1 - 3.1e-17 62.1 0.0 8.9e-17 60.6 0.0 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KPI35841.1 - 0.083 12.7 0.0 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain HSP20 PF00011.16 KPI35842.1 - 1.3e-11 44.2 0.0 1.9e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Tachylectin PF14517.1 KPI35842.1 - 0.035 13.4 0.0 0.07 12.4 0.0 1.4 2 0 0 2 2 2 0 Tachylectin Methyltransf_23 PF13489.1 KPI35843.1 - 1.4e-10 41.1 0.1 5.9e-10 39.0 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI35843.1 - 0.0074 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI35843.1 - 0.0084 16.5 0.0 0.027 14.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain BolA PF01722.13 KPI35843.1 - 0.085 12.8 2.2 3.2 7.7 0.0 3.3 3 1 1 4 4 4 0 BolA-like protein zf-C2H2 PF00096.21 KPI35845.1 - 0.0013 18.9 11.9 0.026 14.8 1.1 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI35845.1 - 0.06 13.6 10.6 0.39 11.1 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Sfi1 PF08457.5 KPI35846.1 - 3.8e-07 28.8 49.3 0.00013 20.5 10.5 3.0 1 1 1 2 2 2 2 Sfi1 spindle body protein Med25_NR-box PF11244.3 KPI35846.1 - 0.64 10.4 7.9 2.2 8.8 5.5 2.0 1 0 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing NYN_YacP PF05991.6 KPI35846.1 - 5.4 6.7 16.0 0.19 11.4 0.7 3.2 3 0 0 3 3 3 0 YacP-like NYN domain Glyco_transf_22 PF03901.12 KPI35848.1 - 1.6e-65 221.7 21.8 3e-39 135.2 3.2 2.0 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family PMT_2 PF13231.1 KPI35848.1 - 5.2e-05 23.2 8.8 5.2e-05 23.2 6.1 2.5 1 1 1 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Snf7 PF03357.16 KPI35849.1 - 3.5e-33 114.4 5.2 3.5e-33 114.4 3.6 1.4 1 1 0 1 1 1 1 Snf7 DUF2520 PF10728.4 KPI35849.1 - 0.0019 17.6 0.1 0.0038 16.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2520) NARP1 PF12569.3 KPI35849.1 - 0.022 13.5 3.3 0.043 12.5 2.3 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Nsp1_C PF05064.8 KPI35849.1 - 0.051 13.2 0.6 0.051 13.2 0.4 2.3 3 0 0 3 3 3 0 Nsp1-like C-terminal region DUF2203 PF09969.4 KPI35849.1 - 0.3 11.3 3.7 0.88 9.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF826 PF05696.6 KPI35849.1 - 0.32 11.1 5.5 0.92 9.6 3.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF826) HSCB_C PF07743.8 KPI35849.1 - 4.1 7.9 10.9 8.1 6.9 0.3 2.9 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain Pyr_redox_dim PF02852.17 KPI35850.1 - 1.9e-39 134.0 1.5 3.6e-39 133.2 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KPI35850.1 - 6.3e-36 124.1 13.3 2.8e-35 122.0 9.2 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI35850.1 - 1e-20 73.9 7.3 1e-20 73.8 0.6 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI35850.1 - 2.5e-08 34.2 0.0 0.00012 22.2 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI35850.1 - 1.2e-07 30.9 8.3 1.6e-05 23.9 2.9 2.9 2 1 0 2 2 2 2 Glucose inhibited division protein A K_oxygenase PF13434.1 KPI35850.1 - 2.3e-07 30.0 0.3 0.014 14.3 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 KPI35850.1 - 6.6e-07 28.7 0.2 6.6e-07 28.7 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI35850.1 - 9.2e-07 28.8 3.3 0.011 15.7 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI35850.1 - 3.6e-05 22.8 9.7 6.2e-05 22.0 1.3 3.0 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 KPI35850.1 - 5.2e-05 21.8 11.8 0.027 12.9 0.7 4.1 4 0 0 4 4 4 3 HI0933-like protein AlaDh_PNT_C PF01262.16 KPI35850.1 - 0.00091 18.8 0.9 0.033 13.7 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KPI35850.1 - 0.0031 16.6 4.9 0.0033 16.5 0.1 2.5 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.13 KPI35850.1 - 0.008 15.8 0.6 0.027 14.1 0.4 2.0 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 KPI35850.1 - 0.018 13.9 18.7 0.22 10.3 1.0 4.1 2 2 1 4 4 4 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KPI35850.1 - 0.071 12.1 10.8 2.4 7.1 0.3 3.9 3 1 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.7 KPI35850.1 - 0.92 8.3 2.7 2 7.2 0.1 2.5 2 1 0 2 2 2 0 Lycopene cyclase protein adh_short PF00106.20 KPI35851.1 - 4.7e-25 88.4 0.0 6e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI35851.1 - 7.2e-24 84.8 0.0 8.5e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI35851.1 - 6.5e-07 29.1 0.0 9.1e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI35851.1 - 0.00016 21.2 0.1 0.00025 20.5 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family zf-CCCH PF00642.19 KPI35852.1 - 0.47 10.2 3.4 1.4 8.6 2.4 1.8 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Transglut_N PF00868.15 KPI35854.1 - 0.029 14.3 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase family Lactonase PF10282.4 KPI35855.1 - 4.1e-17 62.2 0.0 6.3e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.7 KPI35855.1 - 0.00054 19.4 0.0 0.0017 17.7 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region DEAD PF00270.24 KPI35856.1 - 2.8e-43 147.3 0.1 4.8e-43 146.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI35856.1 - 5.1e-20 71.1 0.1 1.4e-19 69.6 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI35856.1 - 0.00032 20.5 0.0 0.00058 19.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 KPI35856.1 - 0.1 11.6 0.1 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF3628 PF12300.3 KPI35856.1 - 0.77 9.7 6.9 2 8.4 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) NAD_binding_10 PF13460.1 KPI35857.1 - 1.3e-09 38.3 0.0 2.2e-09 37.5 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI35857.1 - 0.0008 18.9 0.0 0.0013 18.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KPI35857.1 - 0.00083 18.6 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 KPI35857.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TBP PF00352.16 KPI35858.1 - 4.4e-69 227.8 0.0 4.8e-35 118.7 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KPI35858.1 - 0.00011 22.1 0.0 0.34 10.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) zf-MYND PF01753.13 KPI35859.1 - 3.2e-13 49.3 8.0 5.3e-13 48.6 5.6 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 KPI35859.1 - 0.012 14.8 1.8 0.024 13.9 1.3 1.4 1 0 0 1 1 1 0 Life-span regulatory factor zf-ribbon_3 PF13248.1 KPI35859.1 - 0.039 13.1 1.2 0.098 11.8 0.9 1.7 1 0 0 1 1 1 0 zinc-ribbon domain MCPsignal PF00015.16 KPI35860.1 - 0.06 12.8 4.8 0.086 12.3 0.2 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3921 PF13060.1 KPI35860.1 - 0.094 12.5 0.5 0.54 10.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3921) Zn_clus PF00172.13 KPI35861.1 - 7.7e-09 35.3 13.4 1.2e-08 34.7 9.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Histone PF00125.19 KPI35862.1 - 1.9e-15 56.7 0.3 2.3e-15 56.4 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KPI35862.1 - 4.9e-05 23.4 0.1 6.6e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KPI35862.1 - 7.1e-05 22.6 0.2 0.0001 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KPI35862.1 - 0.00011 22.2 0.1 0.00019 21.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KPI35862.1 - 0.0026 17.4 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 KPI35862.1 - 0.011 14.9 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID_20kDa PF03847.8 KPI35862.1 - 0.049 13.9 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Cutinase PF01083.17 KPI35863.1 - 6.3e-51 172.6 6.7 7.4e-51 172.4 4.6 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KPI35863.1 - 2.4e-07 30.3 0.3 3.3e-07 29.9 0.2 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.11 KPI35863.1 - 0.081 12.3 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Vint PF14623.1 KPI35864.1 - 2.8e-44 150.4 0.0 9e-44 148.8 0.0 1.8 2 0 0 2 2 2 1 Hint-domain Vwaint PF14624.1 KPI35864.1 - 8.1e-22 77.1 0.0 1.7e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.1 KPI35864.1 - 6.4e-18 65.4 0.0 1.1e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KPI35864.1 - 1.1e-14 54.6 0.0 8.1e-14 51.7 0.0 2.4 3 1 0 3 3 3 1 von Willebrand factor type A domain VWA_3 PF13768.1 KPI35864.1 - 2.5e-09 37.0 0.1 1.9e-08 34.1 0.1 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain 7tm_1 PF00001.16 KPI35865.1 - 0.0008 18.6 0.6 0.022 13.9 0.4 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sec61_beta PF03911.11 KPI35865.1 - 0.018 14.8 0.1 0.074 12.8 0.1 2.0 1 0 0 1 1 1 0 Sec61beta family Arylsulfotrans PF05935.6 KPI35866.1 - 1.1e-20 73.6 0.0 4.8e-08 31.9 0.0 3.2 1 1 2 3 3 3 3 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.1 KPI35866.1 - 3.7e-16 59.1 0.0 8.4e-16 57.9 0.0 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.1 KPI35866.1 - 8.6e-05 22.1 0.0 0.00082 18.9 0.0 2.4 1 1 0 2 2 2 1 PQQ-like domain Syd PF07348.7 KPI35868.1 - 0.081 12.2 0.1 0.083 12.2 0.1 1.2 1 0 0 1 1 1 0 Syd protein (SUKH-2) AurF PF11583.3 KPI35868.1 - 0.17 10.7 0.5 0.21 10.4 0.3 1.1 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF TAP35_44 PF07265.6 KPI35868.1 - 0.22 11.2 1.8 0.45 10.2 0.2 1.9 2 0 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 Fungal_trans PF04082.13 KPI35869.1 - 4.3e-20 71.6 0.1 6.7e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lum_binding PF00677.12 KPI35870.1 - 1.1e-38 131.0 0.2 1.4e-21 76.1 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain MFS_1 PF07690.11 KPI35872.1 - 1.2e-33 116.3 27.1 1.8e-33 115.7 18.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily SpoVAB PF13782.1 KPI35872.1 - 0.0041 17.0 0.1 0.011 15.7 0.1 1.7 1 0 0 1 1 1 1 Stage V sporulation protein AB A_deaminase PF00962.17 KPI35873.1 - 3.3e-45 154.4 0.0 8.3e-45 153.1 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase PRP21_like_P PF12230.3 KPI35874.1 - 0.0012 18.3 1.5 0.0015 18.0 1.1 1.1 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Mito_carr PF00153.22 KPI35875.1 - 6.6e-56 186.0 6.2 7.8e-23 80.0 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Rax2 PF12768.2 KPI35876.1 - 0.1 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF1509 PF07420.6 KPI35876.1 - 9.6 5.3 12.0 13 4.8 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) E1_dh PF00676.15 KPI35878.1 - 1.5e-16 59.9 0.1 2.1e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component ADIP PF11559.3 KPI35879.1 - 0.63 9.9 19.5 2.5 7.9 4.5 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 KPI35879.1 - 5.5 6.8 18.3 11 5.8 5.5 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Perilipin PF03036.11 KPI35879.1 - 9.3 4.9 15.9 0.47 9.2 1.1 2.4 3 0 0 3 3 3 0 Perilipin family NPR2 PF06218.6 KPI35880.1 - 6.9e-97 324.8 0.0 1.5e-69 234.7 0.0 2.2 1 1 1 2 2 2 2 Nitrogen permease regulator 2 GST_N_3 PF13417.1 KPI35881.1 - 1.4e-10 41.2 0.0 2.4e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KPI35881.1 - 7.2e-07 29.1 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KPI35881.1 - 5.5e-06 26.4 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KPI35881.1 - 8.4e-06 26.1 0.0 1.4e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KPI35881.1 - 1.7e-05 24.6 0.0 3.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KPI35881.1 - 0.0061 16.4 0.0 0.018 14.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain WD40 PF00400.27 KPI35882.1 - 2.8e-13 49.1 6.0 3.2e-05 23.6 0.0 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF3639 PF12341.3 KPI35882.1 - 2.1e-06 27.5 4.2 2.7e-06 27.2 0.6 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3639) VID27 PF08553.5 KPI35882.1 - 0.0014 16.9 0.0 0.0053 15.0 0.0 1.7 2 0 0 2 2 2 1 VID27 cytoplasmic protein IKI3 PF04762.7 KPI35882.1 - 0.017 12.9 0.1 0.043 11.6 0.1 1.4 1 1 0 1 1 1 0 IKI3 family eIF2A PF08662.6 KPI35882.1 - 0.16 11.6 0.2 0.68 9.6 0.0 2.1 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Clathrin PF00637.15 KPI35883.1 - 8.8e-17 61.0 0.4 6e-15 55.0 0.1 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.27 KPI35883.1 - 0.0047 16.7 0.0 1.1 9.2 0.0 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat Vps39_2 PF10367.4 KPI35883.1 - 0.02 15.0 0.0 0.13 12.4 0.0 2.3 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Bestrophin PF01062.16 KPI35883.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel TPR_7 PF13176.1 KPI35883.1 - 0.13 12.1 0.6 0.65 9.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KPI35883.1 - 0.14 12.1 0.4 0.83 9.7 0.2 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-RING_5 PF14634.1 KPI35883.1 - 0.16 11.7 0.8 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 zinc-RING finger domain GAT PF03127.9 KPI35884.1 - 0.14 12.1 0.8 21 5.1 0.0 2.6 2 0 0 2 2 2 0 GAT domain MAPEG PF01124.13 KPI35885.1 - 4.7e-12 45.6 3.3 5.7e-12 45.3 2.3 1.2 1 0 0 1 1 1 1 MAPEG family AhpC-TSA_2 PF13911.1 KPI35886.1 - 3.9e-15 55.7 0.0 1e-14 54.4 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme polyprenyl_synt PF00348.12 KPI35887.1 - 4.3e-61 206.0 0.0 5.5e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 KPI35887.1 - 0.059 12.5 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain CKAP2_C PF15297.1 KPI35887.1 - 0.089 11.5 0.1 0.16 10.7 0.1 1.4 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Cpn60_TCP1 PF00118.19 KPI35888.1 - 4e-116 388.5 11.1 4.6e-116 388.3 7.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ChlI PF13541.1 KPI35888.1 - 0.037 13.5 0.4 0.093 12.2 0.3 1.6 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase HAP1_N PF04849.8 KPI35888.1 - 0.091 11.6 0.1 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF1547 PF07577.6 KPI35888.1 - 2.4 7.8 5.1 0.84 9.3 0.4 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1547) Fungal_trans_2 PF11951.3 KPI35889.1 - 1.9e-08 33.3 2.0 1.9e-05 23.4 0.1 2.1 1 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI35889.1 - 1.6e-05 24.6 11.5 1.6e-05 24.6 8.0 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu_amine_oxid PF01179.15 KPI35890.1 - 2.3e-93 313.1 0.5 1.1e-92 310.9 0.2 1.8 2 0 0 2 2 2 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 KPI35890.1 - 1.3e-07 31.4 0.1 3.5e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 KPI35890.1 - 0.0014 18.6 0.0 0.03 14.3 0.0 2.3 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Pyridoxal_deC PF00282.14 KPI35891.1 - 5.2e-76 255.5 0.0 7.6e-76 254.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain YagB_YeeU_YfjZ PF06154.6 KPI35891.1 - 0.057 13.6 0.0 0.43 10.8 0.0 2.1 2 0 0 2 2 2 0 YagB/YeeU/YfjZ family AAA_2 PF07724.9 KPI35892.1 - 1.6e-39 135.5 0.0 2.3e-38 131.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KPI35892.1 - 7.9e-15 55.2 0.0 1.5e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KPI35892.1 - 1.2e-06 28.3 0.0 2.9e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.4 KPI35892.1 - 1.2e-05 25.0 0.0 3.3e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Mg_chelatase PF01078.16 KPI35892.1 - 8.6e-05 21.7 0.1 0.0079 15.3 0.0 3.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KPI35892.1 - 0.00024 20.6 0.1 0.072 12.5 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_22 PF13401.1 KPI35892.1 - 0.00033 20.8 0.2 0.0051 16.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KPI35892.1 - 0.00071 20.3 0.2 0.0025 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KPI35892.1 - 0.00077 18.9 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 KPI35892.1 - 0.0011 19.0 1.0 0.0019 18.1 0.1 1.9 2 1 0 2 2 1 1 AAA ATPase domain AAA_24 PF13479.1 KPI35892.1 - 0.0033 17.0 0.0 0.0065 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KPI35892.1 - 0.0067 15.5 0.2 0.13 11.2 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KPI35892.1 - 0.015 15.2 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KPI35892.1 - 0.032 13.6 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KPI35892.1 - 0.046 13.8 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 KPI35892.1 - 0.051 13.4 0.5 0.46 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 KPI35892.1 - 0.061 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.18 KPI35892.1 - 0.062 12.0 0.2 0.17 10.6 0.1 1.6 1 1 0 1 1 1 0 MCM2/3/5 family NACHT PF05729.7 KPI35892.1 - 0.12 11.9 0.2 0.98 9.0 0.1 2.2 1 1 0 1 1 1 0 NACHT domain Kinesin PF00225.18 KPI35893.1 - 1e-14 54.0 0.0 1.4e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Amidase PF01425.16 KPI35894.1 - 1.1e-69 235.4 0.0 1.8e-54 185.2 0.0 2.4 2 1 1 3 3 3 2 Amidase GFO_IDH_MocA PF01408.17 KPI35895.1 - 5e-26 91.5 0.1 7.7e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KPI35895.1 - 1.9e-10 40.5 1.6 2.2e-10 40.3 0.1 2.0 2 1 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 KPI35895.1 - 0.00017 21.8 0.1 0.00032 20.9 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 KPI35895.1 - 0.0061 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain DapB_N PF01113.15 KPI35895.1 - 0.019 14.8 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 KPI35895.1 - 0.023 13.6 0.1 0.036 13.0 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase RepA1_leader PF08048.7 KPI35896.1 - 0.12 12.4 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Tap RepA1 leader peptide Dehydratase_hem PF13816.1 KPI35897.1 - 4e-75 252.7 0.0 3.6e-48 164.2 0.0 2.1 2 0 0 2 2 2 2 Haem-containing dehydratase DUF4188 PF13826.1 KPI35897.1 - 1.7e-06 28.1 0.0 0.00017 21.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) Cyd_oper_YbgE PF09600.5 KPI35898.1 - 0.14 12.3 0.2 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 Cyd operon protein YbgE (Cyd_oper_YbgE) DUF155 PF02582.9 KPI35899.1 - 3.8e-37 127.8 0.0 7.2e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 tRNA-synt_2b PF00587.20 KPI35900.1 - 9.2e-21 74.1 0.0 1.3e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Vps4_C PF09336.5 KPI35900.1 - 0.094 12.6 0.1 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain PTCB-BRCT PF12738.2 KPI35901.1 - 1.2e-05 25.0 0.0 3.1e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KPI35901.1 - 0.00055 20.0 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain FAD_binding_3 PF01494.14 KPI35902.1 - 5.8e-16 58.4 2.7 1.2e-08 34.3 0.0 3.7 3 2 1 4 4 4 3 FAD binding domain SE PF08491.5 KPI35902.1 - 0.00078 18.3 0.0 0.14 10.9 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.1 KPI35902.1 - 0.034 14.1 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.11 KPI35904.1 - 4.2e-24 84.9 29.6 4.2e-24 84.9 20.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1240 PF06836.7 KPI35904.1 - 1.3 9.3 5.1 0.72 10.1 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) MaoC_dehydratas PF01575.14 KPI35906.1 - 2.3e-25 88.3 0.0 4.8e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KPI35906.1 - 3e-15 56.1 0.9 2e-08 34.1 0.2 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Alpha-amylase_C PF02806.13 KPI35907.1 - 2.5e-25 88.4 0.1 6.9e-25 87.0 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 KPI35907.1 - 7.9e-20 71.4 0.1 2e-15 56.9 0.1 2.4 1 1 0 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 KPI35907.1 - 8.8e-17 60.9 0.0 3.3e-16 59.1 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Peptidase_S15 PF02129.13 KPI35908.1 - 1.4e-37 129.5 0.0 2.1e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KPI35908.1 - 1.4e-36 126.4 0.2 2.2e-36 125.7 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_5 PF12695.2 KPI35908.1 - 0.00027 20.7 0.0 0.00053 19.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI35908.1 - 0.034 14.0 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hairpins PF04877.7 KPI35910.1 - 2.2 7.6 9.4 2.5 7.4 6.5 1.0 1 0 0 1 1 1 0 HrpZ DUF1547 PF07577.6 KPI35911.1 - 0.046 13.3 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1547) Epimerase PF01370.16 KPI35912.1 - 0.0006 19.3 0.0 0.00099 18.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI35912.1 - 0.0052 16.8 0.0 0.023 14.7 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KPI35912.1 - 0.046 12.6 0.0 7.3 5.4 0.0 2.4 2 0 0 2 2 2 0 Male sterility protein MFS_1 PF07690.11 KPI35913.1 - 4.3e-07 28.9 6.6 6e-07 28.4 4.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF46 PF01864.12 KPI35913.1 - 0.029 14.2 0.3 0.059 13.2 0.2 1.5 1 0 0 1 1 1 0 Putative integral membrane protein DUF46 FtsX PF02687.16 KPI35913.1 - 0.089 12.5 5.8 0.086 12.6 0.5 2.3 1 1 2 3 3 3 0 FtsX-like permease family Sugar_tr PF00083.19 KPI35914.1 - 7.4e-85 285.1 25.0 1.1e-84 284.6 17.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI35914.1 - 2.1e-27 95.7 23.6 2.1e-27 95.7 16.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF791 PF05631.9 KPI35914.1 - 4e-05 22.4 1.3 4e-05 22.4 0.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF791) Phage_holin_2 PF04550.7 KPI35914.1 - 0.033 14.2 0.5 0.033 14.2 0.3 2.5 2 1 0 2 2 2 0 Phage holin family 2 DUF3982 PF13138.1 KPI35915.1 - 0.021 14.7 0.1 0.063 13.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3982) Aldedh PF00171.17 KPI35916.1 - 2.1e-121 405.5 5.7 4.2e-119 397.9 3.9 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KPI35916.1 - 0.00011 21.4 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) DHquinase_I PF01487.10 KPI35917.1 - 4.9e-33 114.6 0.0 7.4e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 KPI35917.1 - 8.5e-17 60.9 0.0 2.2e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 KPI35917.1 - 1.5e-13 50.8 0.0 3.5e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 KPI35917.1 - 3.2e-10 40.2 0.0 7.6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Abhydrolase_6 PF12697.2 KPI35918.1 - 1.6e-31 109.9 0.9 2e-31 109.6 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI35918.1 - 2e-14 53.5 0.1 2.6e-14 53.1 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI35918.1 - 7.7e-13 48.5 0.1 2.1e-09 37.3 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.8 KPI35918.1 - 1.9e-05 24.3 0.1 7.1e-05 22.4 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 KPI35918.1 - 0.0028 17.1 0.1 0.0065 15.9 0.0 1.8 1 1 0 1 1 1 1 Putative esterase DUF2920 PF11144.3 KPI35918.1 - 0.019 13.9 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) LCAT PF02450.10 KPI35918.1 - 0.031 13.2 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.3 KPI35918.1 - 0.041 13.7 0.1 0.12 12.2 0.1 1.8 1 1 0 1 1 1 0 Putative lysophospholipase Thioesterase PF00975.15 KPI35918.1 - 0.12 12.6 0.2 0.26 11.4 0.1 1.8 1 1 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.16 KPI35918.1 - 0.12 11.5 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KPI35919.1 - 3.1e-22 79.5 0.0 3.7e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI35919.1 - 4.3e-10 39.5 0.1 1.4e-09 37.8 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI35919.1 - 1.8e-07 31.0 0.1 6.9e-07 29.1 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KPI35919.1 - 0.0014 17.9 0.4 0.0025 17.1 0.1 1.5 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 KPI35919.1 - 0.009 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.8 KPI35919.1 - 0.01 15.2 0.3 0.24 10.7 0.2 2.3 1 1 0 1 1 1 0 Serine hydrolase (FSH1) PhoPQ_related PF10142.4 KPI35919.1 - 0.015 13.8 0.1 0.026 12.9 0.1 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein BAAT_C PF08840.6 KPI35919.1 - 0.12 12.0 0.0 0.7 9.5 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal HET PF06985.6 KPI35920.1 - 1.7e-24 86.5 0.1 3.8e-24 85.4 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_N PF08240.7 KPI35921.1 - 2.1e-08 33.9 0.0 4.8e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain HeLo PF14479.1 KPI35922.1 - 4.9e-15 55.8 2.2 4.1e-12 46.3 0.0 2.8 2 1 1 3 3 3 2 Prion-inhibition and propagation NACHT PF05729.7 KPI35922.1 - 3.6e-06 26.7 0.1 1e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KPI35922.1 - 6.1e-05 23.0 1.7 0.0014 18.6 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KPI35922.1 - 0.00019 21.6 0.1 0.001 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KPI35922.1 - 0.027 13.3 0.0 0.51 9.1 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain PIF1 PF05970.9 KPI35922.1 - 0.088 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase E1-E2_ATPase PF00122.15 KPI35924.1 - 8.3e-49 165.6 0.0 1.8e-48 164.6 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KPI35924.1 - 4e-33 115.6 0.1 1.1e-32 114.1 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KPI35924.1 - 1.4e-16 60.4 0.5 3.1e-09 36.8 0.0 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.2 KPI35924.1 - 4.1e-09 36.8 0.0 9.1e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KPI35924.1 - 5.8e-05 22.7 0.0 0.0085 15.6 0.0 2.7 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Fer2_4 PF13510.1 KPI35924.1 - 0.085 12.6 0.4 0.29 10.9 0.3 1.9 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF3431 PF11913.3 KPI35925.1 - 2.4e-78 262.6 1.4 2.9e-78 262.3 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF4254 PF14063.1 KPI35925.1 - 0.0059 16.2 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4254) IGPS PF00218.16 KPI35926.1 - 1.1e-94 316.1 0.0 1.8e-94 315.5 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 KPI35926.1 - 8.4e-50 168.9 0.0 1.5e-49 168.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.17 KPI35926.1 - 6.9e-46 156.2 0.0 1.1e-43 149.0 0.0 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 KPI35926.1 - 1e-05 25.0 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 KPI35926.1 - 0.00043 19.8 0.1 0.092 12.2 0.1 2.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 KPI35926.1 - 0.014 14.6 0.8 0.18 11.0 0.0 2.9 4 0 0 4 4 4 0 Histidine biosynthesis protein NanE PF04131.9 KPI35926.1 - 0.016 14.1 1.1 1.1 8.1 0.1 3.1 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Alpha-L-AF_C PF06964.7 KPI35927.1 - 2.5e-35 121.8 0.1 3.6e-35 121.3 0.1 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Peptidase_S10 PF00450.17 KPI35928.1 - 7.3e-130 433.8 0.2 8.9e-130 433.5 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 KPI35928.1 - 3e-09 37.0 0.0 4.9e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 KPI35928.1 - 0.002 18.0 0.1 0.058 13.2 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family ADH_N PF08240.7 KPI35929.1 - 3.2e-28 97.6 1.7 5.6e-28 96.8 1.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI35929.1 - 3.7e-22 78.2 0.2 3.7e-22 78.2 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI35929.1 - 0.00047 21.0 0.1 0.0008 20.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KPI35929.1 - 0.00085 18.5 0.2 0.0014 17.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KPI35929.1 - 0.048 13.2 0.2 0.082 12.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 KPI35929.1 - 0.076 13.0 0.2 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 NADH(P)-binding DUF1967 PF09269.6 KPI35929.1 - 0.1 12.3 0.1 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Mito_fiss_reg PF05308.6 KPI35931.1 - 0.56 9.5 4.9 0.58 9.4 3.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KPI35931.1 - 0.8 8.9 4.8 0.86 8.8 3.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Glyoxalase_2 PF12681.2 KPI35932.1 - 2.9e-06 27.8 0.1 2.6e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.20 KPI35932.1 - 0.00013 21.9 0.0 0.00052 19.9 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Peptidase_M24 PF00557.19 KPI35934.1 - 1.8e-52 177.9 0.5 2.5e-52 177.4 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KPI35934.1 - 6.8e-26 90.2 0.0 1.4e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain MFS_1 PF07690.11 KPI35936.1 - 2.1e-38 131.9 41.6 3.1e-38 131.3 28.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MMPL PF03176.10 KPI35936.1 - 0.093 11.4 8.8 0.011 14.5 2.5 1.9 2 0 0 2 2 2 0 MMPL family Ycf1 PF05758.7 KPI35937.1 - 0.47 8.1 7.7 0.46 8.1 5.3 1.2 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 KPI35937.1 - 1.5 7.3 14.4 1.9 7.0 10.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 KPI35937.1 - 6.6 4.2 11.6 8 3.9 8.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Trypan_PARP PF05887.6 KPI35937.1 - 7.4 6.3 19.9 15 5.4 13.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FRG1 PF06229.7 KPI35938.1 - 4.3e-24 85.0 1.6 3.5e-23 82.0 0.1 2.5 2 1 0 2 2 2 1 FRG1-like family Fungal_trans PF04082.13 KPI35940.1 - 4.4e-10 38.8 1.7 6.7e-10 38.2 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA_11 PF13086.1 KPI35941.1 - 1.7e-25 90.0 0.5 2.6e-25 89.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KPI35941.1 - 3.9e-24 85.1 0.0 3.8e-20 72.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 KPI35941.1 - 7.9e-08 31.9 0.0 2e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KPI35941.1 - 1.1e-05 25.1 0.0 0.0001 21.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 KPI35941.1 - 0.00016 21.0 0.0 0.00029 20.1 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.4 KPI35941.1 - 0.001 18.1 0.0 0.0072 15.3 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.1 KPI35941.1 - 0.0033 17.5 0.0 0.0099 16.0 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 KPI35941.1 - 0.0035 16.8 0.0 0.39 10.2 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 KPI35941.1 - 0.093 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 KPI35941.1 - 0.097 12.8 0.2 0.35 11.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_47 PF01532.15 KPI35942.1 - 4.7e-149 496.9 0.0 3e-125 418.4 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 SMC_N PF02463.14 KPI35945.1 - 2e-23 82.7 0.0 1.6e-22 79.8 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KPI35945.1 - 5.7e-10 39.8 27.4 5.7e-10 39.8 19.0 4.6 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KPI35945.1 - 9.2e-08 32.3 0.5 3e-05 24.1 0.4 2.6 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KPI35945.1 - 7.1e-05 22.0 0.0 0.00019 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KPI35945.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KPI35945.1 - 0.47 10.7 14.5 0.82 9.9 0.0 5.0 4 2 0 4 4 4 0 ABC transporter Nup188 PF10487.4 KPI35946.1 - 3e-22 78.4 0.4 2.6e-21 75.3 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 2-oxoacid_dh PF00198.18 KPI35947.1 - 8.2e-64 215.0 0.3 1.4e-63 214.2 0.2 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 KPI35947.1 - 3.5e-11 42.5 0.0 7.6e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain ADH_zinc_N PF00107.21 KPI35948.1 - 1.3e-20 73.3 0.1 1.8e-20 72.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 KPI35948.1 - 1.5e-05 24.1 0.1 1.7e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KPI35948.1 - 3.1e-05 24.0 0.0 4.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ADH_zinc_N_2 PF13602.1 KPI35948.1 - 0.00016 22.6 0.1 0.00021 22.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KPI35948.1 - 0.00022 20.4 0.0 0.00034 19.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KPI35948.1 - 0.00041 19.5 0.6 0.00066 18.8 0.3 1.3 1 1 0 1 1 1 1 FAD binding domain ThiF PF00899.16 KPI35948.1 - 0.00088 19.1 1.9 0.0098 15.7 0.2 2.2 1 1 1 2 2 2 1 ThiF family adh_short PF00106.20 KPI35948.1 - 0.001 18.9 0.4 0.002 18.0 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KPI35948.1 - 0.0026 17.2 0.1 0.0033 16.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CPSase_L_chain PF00289.17 KPI35948.1 - 0.0033 17.5 0.2 0.0059 16.7 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain TrkA_N PF02254.13 KPI35948.1 - 0.01 15.8 0.1 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 KPI35948.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KPI35948.1 - 0.014 15.0 0.6 0.13 11.9 0.4 2.0 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KPI35948.1 - 0.021 15.2 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 KPI35948.1 - 0.022 14.7 0.8 0.037 14.0 0.4 1.5 1 1 0 1 1 1 0 NADH(P)-binding Semialdhyde_dh PF01118.19 KPI35948.1 - 0.032 14.5 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 KPI35948.1 - 0.034 14.5 0.6 0.089 13.1 0.4 1.8 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DFP PF04127.10 KPI35948.1 - 0.044 13.3 1.0 0.047 13.2 0.1 1.5 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein NAD_Gly3P_dh_N PF01210.18 KPI35948.1 - 0.055 13.2 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus XdhC_C PF13478.1 KPI35948.1 - 0.064 13.5 0.1 0.097 12.9 0.1 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain KR PF08659.5 KPI35948.1 - 0.069 12.8 0.8 0.15 11.7 0.6 1.6 1 1 0 1 1 1 0 KR domain DapB_N PF01113.15 KPI35948.1 - 0.11 12.4 1.0 1.7 8.6 0.1 2.3 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_7 PF13241.1 KPI35948.1 - 0.11 12.8 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding HET PF06985.6 KPI35950.1 - 1e-17 64.6 0.0 2.3e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hyd_65N_2 PF14498.1 KPI35952.1 - 3.7e-58 196.9 1.4 9.9e-57 192.3 1.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain p450 PF00067.17 KPI35953.1 - 2.3e-51 174.8 0.0 3.7e-50 170.7 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Patatin PF01734.17 KPI35954.1 - 7.2e-20 71.7 0.1 2.3e-19 70.1 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase zf-RING_5 PF14634.1 KPI35954.1 - 0.0014 18.3 5.2 0.0014 18.3 3.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KPI35954.1 - 0.0091 15.8 4.9 0.065 13.1 3.4 2.4 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KPI35954.1 - 0.013 15.1 5.1 0.035 13.7 3.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KPI35954.1 - 0.013 15.2 7.3 0.021 14.6 4.2 2.0 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.1 KPI35954.1 - 0.014 15.1 0.7 0.044 13.4 0.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KPI35954.1 - 2.4 8.2 16.4 0.057 13.4 4.2 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF1445 PF07286.7 KPI35955.1 - 1.3e-51 173.9 0.0 3.6e-51 172.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1445) NAD_binding_10 PF13460.1 KPI35956.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding DUF4260 PF14079.1 KPI35957.1 - 1e-36 125.1 0.2 2.9e-36 123.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4260) Sas10 PF09368.5 KPI35958.1 - 8.8e-28 96.2 8.7 2.8e-27 94.6 6.0 1.9 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KPI35958.1 - 2.4e-10 40.4 0.6 8.1e-10 38.7 0.0 2.3 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Zn_clus PF00172.13 KPI35959.1 - 0.0014 18.4 13.9 0.0023 17.7 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_F17 PF04767.7 KPI35959.1 - 0.69 10.2 5.9 1.4 9.2 4.1 1.5 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein Shikimate_dh_N PF08501.6 KPI35960.1 - 2.6e-15 56.2 0.0 4.5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KPI35960.1 - 1.1e-11 44.9 0.0 2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 KPI35960.1 - 0.0021 17.1 0.3 0.0029 16.6 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase OCD_Mu_crystall PF02423.10 KPI35960.1 - 0.017 13.9 0.1 0.026 13.2 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Tannase PF07519.6 KPI35961.1 - 2.7e-72 244.0 0.0 2.4e-71 240.8 0.0 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KPI35961.1 - 0.00033 20.5 0.3 0.002 18.0 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI35961.1 - 0.0031 17.0 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI35961.1 - 0.0032 16.7 0.1 2.2 7.4 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family TRI12 PF06609.8 KPI35962.1 - 5.9e-36 123.8 28.2 7.9e-36 123.4 19.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI35962.1 - 5.4e-18 64.8 61.1 5.4e-18 64.8 42.3 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI35962.1 - 6e-07 28.4 12.4 6e-07 28.4 8.6 3.0 1 1 0 3 3 3 2 Sugar (and other) transporter FAD_binding_3 PF01494.14 KPI35964.1 - 5.3e-102 341.4 0.0 6.6e-102 341.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI35964.1 - 3e-08 32.9 0.4 0.00042 19.3 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI35964.1 - 2.6e-06 27.4 0.0 7.7e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI35964.1 - 0.0004 19.3 0.0 0.19 10.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KPI35964.1 - 0.00065 19.6 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KPI35964.1 - 0.0072 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KPI35964.1 - 0.043 14.2 0.0 0.56 10.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI35964.1 - 0.098 11.1 0.0 0.42 9.0 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein C1_4 PF07975.7 KPI35965.1 - 0.051 13.5 5.0 0.12 12.4 3.5 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain Hemolysin_N PF12563.3 KPI35965.1 - 0.8 9.1 9.2 1.5 8.2 6.3 1.4 1 1 0 1 1 1 0 Hemolytic toxin N terminal Cation_ATPase_N PF00690.21 KPI35966.1 - 0.023 14.1 0.2 0.18 11.2 0.0 2.2 1 1 1 2 2 2 0 Cation transporter/ATPase, N-terminus Fungal_trans_2 PF11951.3 KPI35967.1 - 0.00026 19.7 0.6 0.00068 18.3 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain AP_endonuc_2 PF01261.19 KPI35968.1 - 1.3e-24 86.7 0.1 1.7e-24 86.2 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel ADH_zinc_N PF00107.21 KPI35969.1 - 1.4e-20 73.1 0.7 2.4e-20 72.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI35969.1 - 4.7e-07 30.7 0.3 1.5e-06 29.1 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI35969.1 - 8.2e-06 25.5 0.0 7.3e-05 22.4 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain PHD PF00628.24 KPI35970.1 - 4.4e-07 29.4 13.8 7.1e-07 28.8 9.6 1.3 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 KPI35970.1 - 0.002 17.8 16.3 0.012 15.3 6.9 2.3 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF164 PF02591.10 KPI35970.1 - 0.27 11.1 4.4 2.1 8.2 0.0 3.2 3 0 0 3 3 3 0 Putative zinc ribbon domain Herpes_UL52 PF03121.10 KPI35970.1 - 0.43 10.3 3.6 0.82 9.4 2.5 1.4 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase FYVE_2 PF02318.11 KPI35970.1 - 2.9 7.8 6.7 2.2 8.1 3.3 1.6 2 0 0 2 2 2 0 FYVE-type zinc finger PHD_2 PF13831.1 KPI35970.1 - 9.9 5.5 16.2 1.2 8.4 7.5 2.2 2 1 0 2 2 2 0 PHD-finger Mid2 PF04478.7 KPI35971.1 - 5.8e-08 32.2 0.1 1e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 KPI35971.1 - 8.1e-07 28.2 0.6 2e-06 27.0 0.4 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 KPI35971.1 - 0.00034 20.3 0.9 0.00048 19.8 0.0 1.6 2 0 0 2 2 2 1 TMEM154 protein family DUF4448 PF14610.1 KPI35971.1 - 0.0042 16.6 0.0 0.0098 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Herpes_gE PF02480.11 KPI35971.1 - 0.0078 14.5 0.2 0.01 14.1 0.1 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E MGC-24 PF05283.6 KPI35971.1 - 0.0089 15.8 7.8 0.0089 15.8 5.4 1.7 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24) RCR PF12273.3 KPI35971.1 - 0.054 14.0 2.2 0.097 13.2 0.0 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF687 PF05095.7 KPI35971.1 - 0.13 10.5 0.0 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF687) Mucin PF01456.12 KPI35971.1 - 0.61 9.8 18.1 0.041 13.6 8.1 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF1180 PF06679.7 KPI35971.1 - 1.1 9.0 10.8 0.039 13.8 2.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Pap_E4 PF02711.9 KPI35971.1 - 2 9.2 7.1 7.5 7.4 0.4 2.3 2 0 0 2 2 2 0 E4 protein adh_short PF00106.20 KPI35972.1 - 8.6e-19 68.0 0.0 3.4e-17 62.8 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI35972.1 - 1.3e-07 31.4 0.0 3.3e-06 26.8 0.0 2.2 1 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KPI35972.1 - 1.7e-05 24.7 0.4 6.4e-05 22.8 0.0 2.1 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 KPI35972.1 - 0.00036 19.6 0.0 0.00059 18.9 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 KPI35972.1 - 0.011 15.7 0.3 0.02 14.9 0.2 1.4 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_7 PF13241.1 KPI35972.1 - 0.015 15.5 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Eno-Rase_NADH_b PF12242.3 KPI35972.1 - 0.021 14.5 0.2 0.04 13.7 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 KPI35972.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KPI35972.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Grp1_Fun34_YaaH PF01184.14 KPI35973.1 - 1.8e-17 63.3 27.2 7e-17 61.4 18.8 1.8 1 1 0 1 1 1 1 GPR1/FUN34/yaaH family MRAP PF15183.1 KPI35973.1 - 1.6 8.3 7.4 0.077 12.6 0.4 2.5 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family Hydantoinase_B PF02538.9 KPI35974.1 - 1.9e-155 518.1 0.0 7.3e-155 516.1 0.0 1.9 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KPI35974.1 - 6.1e-56 189.6 0.0 1.1e-51 175.7 0.0 3.9 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KPI35974.1 - 8.5e-29 100.2 0.1 2e-20 73.0 0.0 3.6 2 1 1 3 3 3 3 Hydantoinase/oxoprolinase N-terminal region AMP-binding PF00501.23 KPI35975.1 - 5.3e-71 239.1 0.0 6.8e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI35975.1 - 7.3e-12 46.0 0.1 1.8e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.19 KPI35976.1 - 5.9e-93 311.8 19.8 7.3e-93 311.5 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI35976.1 - 1.4e-26 93.1 33.0 1.4e-26 93.1 22.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI35976.1 - 5.5e-07 28.3 1.7 5.5e-07 28.3 1.2 3.1 2 1 1 3 3 3 1 MFS/sugar transport protein TRI12 PF06609.8 KPI35976.1 - 8.6e-05 20.9 2.0 0.0002 19.7 1.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KPI35976.1 - 0.0044 16.7 3.8 0.022 14.5 0.0 3.3 3 0 0 3 3 3 1 MFS_1 like family MFS_1 PF07690.11 KPI35977.1 - 2e-36 125.4 37.3 2e-36 125.4 25.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI35977.1 - 6.6e-12 44.7 19.6 6.6e-12 44.7 13.6 3.6 3 1 1 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.8 KPI35977.1 - 7e-07 27.8 5.8 1.3e-06 26.9 4.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) zf-MYND PF01753.13 KPI35978.1 - 1.4e-07 31.2 8.1 3.1e-07 30.1 5.6 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KPI35978.1 - 0.00058 19.6 4.3 0.0015 18.3 3.0 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 KbaA PF14089.1 KPI35978.1 - 0.1 12.1 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation F-box-like_2 PF13013.1 KPI35979.1 - 0.026 14.2 0.0 0.07 12.8 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain HET PF06985.6 KPI35980.1 - 2.1e-29 102.4 0.0 3.3e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_31 PF13847.1 KPI35981.1 - 1.7e-21 76.4 0.0 2.2e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI35981.1 - 1.9e-16 60.3 0.0 3.7e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI35981.1 - 2.5e-16 60.2 0.1 6.3e-16 58.9 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI35981.1 - 1.2e-15 57.7 0.0 2.2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI35981.1 - 6.2e-15 54.9 0.0 1.2e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KPI35981.1 - 8e-14 51.6 0.0 1.2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI35981.1 - 1.4e-13 51.0 0.0 2.4e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI35981.1 - 7.2e-11 42.1 0.2 2.1e-10 40.6 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KPI35981.1 - 5.3e-09 35.9 0.0 1.8e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 KPI35981.1 - 1.1e-05 25.5 0.0 2.9e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 KPI35981.1 - 2e-05 24.0 0.0 5.3e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 KPI35981.1 - 0.0018 17.9 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_19 PF04672.7 KPI35981.1 - 0.022 14.0 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl methyltransferase CmcI PF04989.7 KPI35981.1 - 0.029 13.6 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Methyltransf_3 PF01596.12 KPI35981.1 - 0.051 12.6 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase UPF0020 PF01170.13 KPI35981.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 adh_short PF00106.20 KPI35982.1 - 3.6e-20 72.5 0.5 4.7e-20 72.1 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI35982.1 - 3.3e-14 53.2 0.0 4.4e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KPI35982.1 - 1.4e-09 37.5 0.1 2.9e-09 36.4 0.1 1.4 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.5 KPI35982.1 - 1.2e-07 31.5 0.4 2.2e-07 30.6 0.3 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI35982.1 - 0.00055 19.9 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI35982.1 - 0.007 15.8 0.1 0.012 15.1 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KPI35982.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 KPI35982.1 - 0.12 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Sugar_tr PF00083.19 KPI35983.1 - 4e-100 335.5 24.0 4.5e-100 335.3 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI35983.1 - 1.3e-31 109.6 33.8 1.2e-24 86.7 9.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Lig_chan PF00060.21 KPI35983.1 - 0.78 9.4 6.4 0.33 10.6 0.1 2.7 2 1 0 2 2 2 0 Ligand-gated ion channel Kinesin PF00225.18 KPI35984.1 - 2.7e-40 138.1 0.0 4.6e-40 137.3 0.0 1.3 1 1 0 1 1 1 1 Kinesin motor domain APG6 PF04111.7 KPI35984.1 - 0.75 8.7 5.3 1.1 8.2 3.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 MFS_1 PF07690.11 KPI35985.1 - 8e-29 100.4 21.3 8e-29 100.4 14.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Aa_trans PF01490.13 KPI35986.1 - 8.1e-14 50.9 27.2 1.4e-13 50.1 18.9 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein adh_short PF00106.20 KPI35986.1 - 5.9e-05 23.0 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase FAA_hydrolase PF01557.13 KPI35987.1 - 1.3e-59 201.3 0.0 1.7e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SnoaL_4 PF13577.1 KPI35988.1 - 4.7e-08 33.0 0.0 6.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain Methyltransf_2 PF00891.13 KPI35989.1 - 2.8e-20 72.5 0.7 2.5e-18 66.1 0.1 2.2 1 1 1 2 2 2 2 O-methyltransferase Med13_C PF06333.7 KPI35989.1 - 0.0049 15.4 1.6 0.0073 14.8 1.1 1.1 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal SOG2 PF10428.4 KPI35989.1 - 0.0088 14.7 0.5 0.011 14.4 0.3 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein DUF4597 PF15366.1 KPI35989.1 - 0.25 10.9 2.7 0.34 10.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Fungal_trans PF04082.13 KPI35991.1 - 3e-27 95.1 0.3 6.5e-27 94.0 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI35991.1 - 3e-08 33.4 11.5 5.7e-08 32.5 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KPI35992.1 - 8.8e-35 120.0 27.2 1.1e-34 119.7 18.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KPI35992.1 - 0.00037 20.0 4.4 0.00037 20.0 3.1 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Chitin_synth_2 PF03142.10 KPI35992.1 - 0.0024 16.3 1.5 0.0045 15.4 1.0 1.4 1 0 0 1 1 1 1 Chitin synthase RRM_2 PF04059.7 KPI35994.1 - 1.8e-20 72.7 0.0 2.3e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 Las1 PF04031.8 KPI35995.1 - 5.6e-35 120.2 0.0 7.7e-18 64.6 0.0 2.2 2 0 0 2 2 2 2 Las1-like PI3_PI4_kinase PF00454.22 KPI35996.1 - 5.8e-42 143.7 0.0 1.3e-41 142.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 KPI35996.1 - 5.7e-26 91.1 0.0 2.2e-25 89.2 0.0 2.1 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 KPI35996.1 - 2.2e-10 39.7 0.0 5.4e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 FATC domain GMC_oxred_N PF00732.14 KPI35997.1 - 4.2e-56 190.2 0.0 7.2e-56 189.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI35997.1 - 9e-39 133.0 0.2 1.8e-38 132.0 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KPI35997.1 - 4.4e-08 32.4 1.1 0.003 16.5 0.1 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI35997.1 - 4.7e-05 23.3 0.3 0.00014 21.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KPI35997.1 - 8.2e-05 21.6 0.1 0.013 14.3 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KPI35997.1 - 0.00024 21.0 0.0 0.00044 20.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI35997.1 - 0.00038 19.4 0.1 0.00069 18.6 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KPI35997.1 - 0.002 17.0 0.2 0.01 14.6 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KPI35997.1 - 0.007 14.8 0.2 0.015 13.7 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KPI35997.1 - 0.015 14.3 0.2 0.093 11.8 0.1 2.3 2 0 0 2 2 2 0 Thi4 family Dynamin_N PF00350.18 KPI35999.1 - 1.4e-43 148.5 0.0 2.7e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KPI35999.1 - 1.9e-16 59.7 0.3 3.1e-13 49.1 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KPI35999.1 - 0.002 18.0 0.0 0.0073 16.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KPI35999.1 - 0.003 18.0 0.0 0.0068 16.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 KPI35999.1 - 0.025 14.5 0.2 0.16 11.9 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 KPI35999.1 - 0.056 12.8 0.1 0.36 10.2 0.0 2.4 1 1 0 1 1 1 0 AAA-like domain SRI PF08236.6 KPI35999.1 - 0.1 12.5 0.5 0.23 11.4 0.3 1.5 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain AAA_21 PF13304.1 KPI35999.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain p450 PF00067.17 KPI36000.1 - 2.8e-61 207.4 0.0 4e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 KPI36001.1 - 6.4e-14 51.6 0.1 1.5e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI36001.1 - 0.013 15.2 0.1 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain TAP42 PF04177.7 KPI36002.1 - 5e-75 252.5 0.3 6.2e-75 252.2 0.2 1.0 1 0 0 1 1 1 1 TAP42-like family UPF0075 PF03702.9 KPI36003.1 - 1.3e-81 274.3 0.0 6.7e-81 272.0 0.0 1.8 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0075) FGGY_C PF02782.11 KPI36003.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF1602 PF07673.9 KPI36003.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1602) Ribosomal_L23 PF00276.15 KPI36004.1 - 1.7e-12 47.1 0.5 4.9e-12 45.6 0.3 1.8 1 1 0 1 1 1 1 Ribosomal protein L23 NACHT PF05729.7 KPI36006.1 - 4e-11 42.8 0.1 4.8e-09 36.1 0.0 3.3 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KPI36006.1 - 9.2e-06 25.7 1.9 6.9e-05 22.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KPI36006.1 - 0.0028 17.7 2.2 0.032 14.3 0.0 3.2 2 1 0 3 3 3 1 AAA domain AAA PF00004.24 KPI36006.1 - 0.0047 17.1 0.0 0.22 11.7 0.0 3.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KPI36006.1 - 0.0068 16.1 0.0 0.035 13.7 0.0 2.1 2 1 0 2 2 2 1 Archaeal ATPase SBDS_C PF09377.5 KPI36006.1 - 0.07 12.8 0.5 0.14 11.8 0.4 1.5 1 0 0 1 1 1 0 SBDS protein C-terminal domain ADH_N PF08240.7 KPI36007.1 - 3.1e-29 100.9 2.2 3.7e-29 100.6 0.8 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI36007.1 - 5.4e-17 61.5 0.1 8.2e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI36007.1 - 7.7e-05 23.5 0.0 0.00016 22.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KPI36007.1 - 0.00023 20.7 0.0 0.00051 19.6 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KPI36007.1 - 0.014 15.3 0.2 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain OB_NTP_bind PF07717.11 KPI36008.1 - 1.6e-26 92.3 0.0 3.7e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KPI36008.1 - 5.8e-23 80.8 0.1 1.7e-22 79.3 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KPI36008.1 - 1.9e-10 40.4 0.0 4.3e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KPI36008.1 - 2.8e-05 23.6 0.1 9.5e-05 21.9 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KPI36008.1 - 0.00024 21.2 0.0 0.00077 19.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 KPI36008.1 - 0.0026 17.2 0.0 0.0094 15.4 0.0 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 KPI36008.1 - 0.0048 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 KPI36008.1 - 0.018 14.8 0.0 7.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SE PF00437.15 KPI36008.1 - 0.029 13.2 0.0 0.063 12.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein COMPASS-Shg1 PF05205.7 KPI36009.1 - 2.5e-24 85.5 0.1 5.9e-24 84.4 0.1 1.6 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF3414 PF11894.3 KPI36010.1 - 1.8e-270 900.4 17.7 1.3e-269 897.5 12.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3414) Nab1 PF04902.7 KPI36011.1 - 0.0038 16.7 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in Nab1 GDA1_CD39 PF01150.12 KPI36012.1 - 7.6e-107 357.4 0.0 9.5e-107 357.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family MFS_1 PF07690.11 KPI36013.1 - 1.7e-32 112.5 25.2 1.7e-32 112.5 17.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KPI36014.1 - 4.3e-21 75.3 0.0 1.5e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KPI36014.1 - 5.1e-07 28.9 8.1 0.0021 17.0 2.7 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI36014.1 - 1.9e-06 27.7 1.3 6.6e-06 26.0 0.9 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KPI36014.1 - 4.7e-06 25.9 0.6 7.4e-06 25.2 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KPI36014.1 - 0.00037 20.8 4.6 0.012 16.0 2.3 2.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI36014.1 - 0.00037 20.4 2.0 0.0022 17.8 1.4 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI36014.1 - 0.00053 18.9 7.6 0.0013 17.6 4.9 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KPI36014.1 - 0.0055 15.2 2.7 0.0098 14.3 1.8 1.4 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.5 KPI36014.1 - 0.0058 15.4 0.0 0.0098 14.7 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.12 KPI36014.1 - 0.012 14.7 0.3 0.85 8.6 0.3 2.2 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.9 KPI36014.1 - 0.012 14.2 4.0 0.069 11.7 2.0 2.5 2 1 1 3 3 3 0 Tryptophan halogenase GIDA PF01134.17 KPI36014.1 - 0.017 14.0 6.5 0.026 13.3 4.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KPI36014.1 - 0.024 14.6 0.1 0.087 12.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.4 KPI36014.1 - 0.084 12.6 0.2 0.32 10.7 0.1 2.0 1 0 0 1 1 1 0 Rossmann-like domain Lycopene_cycl PF05834.7 KPI36014.1 - 0.15 10.9 1.4 1.7 7.4 1.0 2.4 1 1 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 KPI36014.1 - 0.25 10.9 2.1 0.63 9.5 1.4 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.19 KPI36014.1 - 0.29 10.1 3.3 19 4.1 1.9 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 KPI36014.1 - 1.4 8.5 3.5 3 7.4 2.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pro_isomerase PF00160.16 KPI36015.1 - 3e-46 157.4 0.1 4.9e-46 156.7 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 KPI36015.1 - 8.9e-07 28.3 1.0 2.8e-06 26.7 0.1 2.3 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 KPI36015.1 - 8.7e-05 22.4 0.0 0.00046 20.0 0.0 2.3 2 1 0 2 2 2 1 U-box domain 2C_adapt PF08793.5 KPI36015.1 - 0.089 12.6 0.3 11 5.9 0.0 2.5 2 0 0 2 2 2 0 2-cysteine adaptor domain GrpB PF04229.9 KPI36017.1 - 3.6e-20 72.3 0.1 8.4e-16 58.1 0.0 2.1 2 0 0 2 2 2 2 GrpB protein Grp1_Fun34_YaaH PF01184.14 KPI36018.1 - 7.1e-28 97.3 15.5 9.5e-28 96.9 10.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family EBV-NA3 PF05009.7 KPI36019.1 - 0.061 12.5 1.7 0.1 11.8 0.2 1.9 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Zn_clus PF00172.13 KPI36020.1 - 6.4e-05 22.7 14.1 0.00013 21.8 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 KPI36021.1 - 2.2e-29 102.9 0.1 2.6e-29 102.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI36021.1 - 8.4e-17 61.4 0.1 3.4e-16 59.5 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI36021.1 - 9e-09 35.2 0.0 2.5e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KPI36021.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 KPI36022.1 - 2e-29 103.1 0.2 2.4e-29 102.8 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI36022.1 - 8.5e-14 51.6 0.0 1e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI36022.1 - 2.5e-09 37.0 0.0 3.9e-09 36.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KPI36022.1 - 0.027 12.9 0.0 0.045 12.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family UVR PF02151.14 KPI36022.1 - 0.45 10.0 2.0 1.1 8.8 0.4 2.4 2 0 0 2 2 2 0 UvrB/uvrC motif Sugar_tr PF00083.19 KPI36023.1 - 5e-49 167.0 17.5 1.9e-48 165.2 12.1 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI36023.1 - 1.3e-09 37.2 36.0 1.1e-05 24.3 7.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DnaJ PF00226.26 KPI36024.1 - 3.4e-21 74.7 0.2 9.5e-21 73.3 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Apolipoprotein PF01442.13 KPI36024.1 - 0.00012 21.6 7.1 0.00012 21.6 4.9 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.7 KPI36024.1 - 0.00033 20.4 7.3 0.00037 20.2 3.3 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) DUF2365 PF10157.4 KPI36024.1 - 0.0014 18.5 0.3 0.002 18.0 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) DUF4164 PF13747.1 KPI36024.1 - 0.0022 18.1 5.2 0.0026 17.8 3.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4164) IFT57 PF10498.4 KPI36024.1 - 0.0026 16.5 8.6 0.0034 16.1 6.0 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 ArsR PF09824.4 KPI36024.1 - 0.0047 16.2 0.5 0.01 15.1 0.4 1.6 1 1 0 1 1 1 1 ArsR transcriptional regulator DUF2450 PF10475.4 KPI36024.1 - 0.005 15.7 7.9 0.14 11.0 2.9 2.3 1 1 1 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Prominin PF05478.6 KPI36024.1 - 0.0082 13.7 2.1 0.01 13.3 1.5 1.1 1 0 0 1 1 1 1 Prominin Reo_sigmaC PF04582.7 KPI36024.1 - 0.02 14.0 0.6 0.025 13.7 0.4 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IZUMO PF15005.1 KPI36024.1 - 0.024 14.6 2.8 0.99 9.4 0.2 2.2 1 1 1 2 2 2 0 Izumo sperm-egg fusion AAA_13 PF13166.1 KPI36024.1 - 0.029 12.8 9.6 0.036 12.5 6.6 1.1 1 0 0 1 1 1 0 AAA domain DUF2756 PF10956.3 KPI36024.1 - 0.032 14.4 0.7 0.053 13.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) Sec8_exocyst PF04048.9 KPI36024.1 - 0.033 13.8 4.8 0.099 12.2 3.2 1.9 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain Rep_3 PF01051.16 KPI36024.1 - 0.034 13.7 2.3 0.059 12.9 1.6 1.4 1 1 0 1 1 1 0 Initiator Replication protein DUF812 PF05667.6 KPI36024.1 - 0.035 12.6 8.3 0.044 12.3 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) NAAA-beta PF15508.1 KPI36024.1 - 0.04 14.2 0.6 1.8 9.0 0.1 2.4 1 1 1 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase NPV_P10 PF05531.7 KPI36024.1 - 0.053 13.7 6.7 1 9.6 1.8 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ArdA PF07275.6 KPI36024.1 - 0.055 13.7 5.5 0.14 12.4 3.8 1.6 1 1 0 1 1 1 0 Antirestriction protein (ArdA) COG2 PF06148.6 KPI36024.1 - 0.058 13.2 3.7 0.2 11.5 1.8 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 APG17 PF04108.7 KPI36024.1 - 0.11 11.3 9.1 0.065 12.0 2.6 2.0 1 1 1 2 2 2 0 Autophagy protein Apg17 DUF2317 PF10079.4 KPI36024.1 - 0.12 10.9 11.6 2.8 6.4 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF948 PF06103.6 KPI36024.1 - 0.13 12.1 8.0 0.55 10.1 5.0 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3053 PF11254.3 KPI36024.1 - 0.13 11.4 4.9 0.11 11.7 2.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3053) Laminin_II PF06009.7 KPI36024.1 - 0.14 11.9 11.7 0.085 12.6 4.7 2.1 1 1 1 2 2 2 0 Laminin Domain II Baculo_PEP_C PF04513.7 KPI36024.1 - 0.14 12.0 7.0 0.5 10.1 4.8 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SDH_alpha PF03313.10 KPI36024.1 - 0.15 11.1 2.5 0.34 9.8 1.2 1.8 1 1 1 2 2 2 0 Serine dehydratase alpha chain MCPsignal PF00015.16 KPI36024.1 - 0.15 11.5 6.0 0.23 10.9 3.9 1.4 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4460 PF14687.1 KPI36024.1 - 0.15 11.8 5.2 0.43 10.3 3.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4460) RmuC PF02646.11 KPI36024.1 - 0.24 10.1 8.0 0.13 11.1 3.3 1.9 1 1 1 2 2 2 0 RmuC family Sec20 PF03908.8 KPI36024.1 - 0.24 11.1 6.1 0.16 11.6 1.3 2.4 1 1 1 2 2 2 0 Sec20 Tektin PF03148.9 KPI36024.1 - 0.25 9.8 11.5 0.33 9.4 7.1 1.6 1 1 0 1 1 1 0 Tektin family Fzo_mitofusin PF04799.8 KPI36024.1 - 0.3 10.4 6.2 0.5 9.7 3.4 1.9 1 1 1 2 2 2 0 fzo-like conserved region DUF4559 PF15112.1 KPI36024.1 - 0.31 10.1 5.6 0.35 9.9 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF883 PF05957.8 KPI36024.1 - 0.36 11.2 5.7 0.16 12.4 2.3 1.8 2 1 0 2 2 1 0 Bacterial protein of unknown function (DUF883) Spc7 PF08317.6 KPI36024.1 - 0.41 9.2 10.8 0.41 9.2 6.9 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Baculo_p24 PF05073.7 KPI36024.1 - 0.41 10.1 6.4 0.34 10.4 3.2 1.7 1 1 1 2 2 2 0 Baculovirus P24 capsid protein HisKA_3 PF07730.8 KPI36024.1 - 0.43 10.9 3.7 1.6 9.1 0.8 2.5 1 1 1 2 2 2 0 Histidine kinase FliH PF02108.11 KPI36024.1 - 0.43 10.4 4.2 1.3 8.9 2.0 2.1 2 0 0 2 2 2 0 Flagellar assembly protein FliH TMPIT PF07851.8 KPI36024.1 - 0.48 9.4 5.7 0.74 8.8 3.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.5 KPI36024.1 - 0.55 10.3 9.5 4.5 7.3 0.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LMBR1 PF04791.11 KPI36024.1 - 0.56 8.7 3.9 0.85 8.1 2.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Cauli_AT PF03233.8 KPI36024.1 - 0.69 9.5 5.3 0.53 9.9 2.4 1.8 1 1 1 2 2 2 0 Aphid transmission protein IncA PF04156.9 KPI36024.1 - 0.69 9.4 11.2 1.8 8.1 7.7 1.9 1 1 0 1 1 1 0 IncA protein ASL_C PF08328.6 KPI36024.1 - 0.7 9.7 6.1 0.69 9.7 2.7 1.9 1 1 1 2 2 2 0 Adenylosuccinate lyase C-terminal DUF148 PF02520.12 KPI36024.1 - 0.77 9.5 13.1 0.38 10.5 6.0 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF148 hDGE_amylase PF14701.1 KPI36024.1 - 0.92 8.3 5.6 1.3 7.8 3.9 1.3 1 1 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Spectrin PF00435.16 KPI36024.1 - 0.96 9.7 9.9 0.5 10.6 4.0 2.1 1 1 0 2 2 2 0 Spectrin repeat LUC7 PF03194.10 KPI36024.1 - 1 8.8 8.3 0.35 10.3 4.1 1.4 2 0 0 2 2 1 0 LUC7 N_terminus VIT1 PF01988.14 KPI36024.1 - 1 8.8 4.1 1.6 8.1 2.8 1.3 1 0 0 1 1 1 0 VIT family DUF651 PF04895.7 KPI36024.1 - 1.5 8.5 4.4 1.4 8.6 0.7 2.3 1 1 2 3 3 3 0 Archaeal protein of unknown function (DUF651) Exonuc_VII_L PF02601.10 KPI36024.1 - 1.6 7.8 7.7 2 7.5 5.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cor1 PF04803.7 KPI36024.1 - 1.7 8.4 11.2 0.49 10.1 5.7 1.7 2 0 0 2 2 1 0 Cor1/Xlr/Xmr conserved region DUF4546 PF15079.1 KPI36024.1 - 1.7 7.7 6.6 1.2 8.2 2.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4546) Atg14 PF10186.4 KPI36024.1 - 1.7 7.5 7.2 1.7 7.5 4.5 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 KPI36024.1 - 1.8 6.8 7.4 1.3 7.3 4.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) BLOC1_2 PF10046.4 KPI36024.1 - 2.4 8.3 10.0 4.6 7.4 4.4 2.5 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4446 PF14584.1 KPI36024.1 - 2.4 7.9 7.0 1.9 8.3 1.9 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) DASH_Dad2 PF08654.5 KPI36024.1 - 2.7 8.0 7.2 8.9 6.3 3.7 2.6 1 1 0 1 1 1 0 DASH complex subunit Dad2 CDC37_N PF03234.9 KPI36024.1 - 5.3 7.3 11.7 6.7 7.0 1.1 2.2 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Syntaxin-6_N PF09177.6 KPI36024.1 - 5.6 7.4 9.3 1.4 9.3 1.0 2.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Uso1_p115_C PF04871.8 KPI36024.1 - 7.4 6.5 15.1 2.6 7.9 8.1 1.8 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DASH_Dam1 PF08653.5 KPI36024.1 - 8.4 6.2 6.7 34 4.2 0.2 3.3 1 1 2 3 3 3 0 DASH complex subunit Dam1 Seryl_tRNA_N PF02403.17 KPI36024.1 - 8.7 6.4 10.8 1.3 9.0 1.4 2.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HSCB_C PF07743.8 KPI36024.1 - 8.8 6.8 11.3 35 4.9 0.8 3.2 1 1 2 3 3 3 0 HSCB C-terminal oligomerisation domain TPR_11 PF13414.1 KPI36025.1 - 1.7e-08 33.9 3.1 4.1e-08 32.7 2.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_12 PF13424.1 KPI36025.1 - 1.4e-05 24.9 1.5 3.2e-05 23.7 1.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KPI36025.1 - 3.5e-05 23.2 4.2 0.0051 16.3 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KPI36025.1 - 0.0008 19.1 4.6 0.13 12.1 0.1 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KPI36025.1 - 0.001 18.6 0.5 0.42 10.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KPI36025.1 - 0.0021 18.1 0.8 0.0038 17.3 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 YukC PF10140.4 KPI36025.1 - 0.0029 16.2 0.0 0.0042 15.7 0.0 1.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC TPR_19 PF14559.1 KPI36025.1 - 0.0041 17.4 1.3 0.009 16.3 0.9 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 KPI36025.1 - 0.12 13.0 5.4 0.2 12.3 1.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KPI36025.1 - 0.34 11.6 2.9 15 6.5 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF2360 PF10152.4 KPI36025.1 - 2.2 8.5 6.1 0.34 11.1 0.3 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF2217 PF10265.4 KPI36025.1 - 5.8 5.5 5.9 0.63 8.7 1.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Ndc1_Nup PF09531.5 KPI36025.1 - 6.6 5.0 7.6 0.18 10.1 0.8 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup GATase_4 PF13230.1 KPI36026.1 - 2.4e-16 59.2 0.0 6.1e-14 51.3 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KPI36026.1 - 1.4e-09 38.0 0.0 2.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KPI36026.1 - 7.4e-07 28.1 0.0 5.2e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Fungal_trans PF04082.13 KPI36027.1 - 9.4e-11 41.0 2.0 1.4e-10 40.5 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PQ-loop PF04193.9 KPI36028.1 - 1.3e-21 75.8 22.0 2e-12 46.4 3.1 3.0 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.13 KPI36028.1 - 0.0024 18.3 2.1 0.0024 18.3 1.4 1.6 2 0 0 2 2 2 1 ER lumen protein retaining receptor Shisa PF13908.1 KPI36028.1 - 0.037 14.2 0.1 0.087 12.9 0.1 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF1345 PF07077.6 KPI36028.1 - 0.33 10.4 4.6 0.22 11.0 0.9 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1345) FA_desaturase PF00487.19 KPI36028.1 - 7.3 5.9 8.2 5.9 6.2 1.8 2.5 1 1 2 3 3 3 0 Fatty acid desaturase DUF718 PF05336.8 KPI36030.1 - 2.7e-31 107.5 0.0 3.3e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Crystall PF00030.14 KPI36030.1 - 0.048 13.5 0.1 0.24 11.3 0.1 2.1 2 1 0 2 2 2 0 Beta/Gamma crystallin Lon_C PF05362.8 KPI36031.1 - 6.8e-69 231.2 0.3 1.7e-68 229.9 0.2 1.7 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KPI36031.1 - 1.6e-27 96.5 0.3 3.8e-27 95.3 0.0 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KPI36031.1 - 5.6e-16 58.9 0.0 4e-15 56.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 KPI36031.1 - 1.5e-07 30.9 0.0 3.7e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 KPI36031.1 - 1.5e-06 27.9 0.0 3.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KPI36031.1 - 2.9e-06 27.4 0.0 1.3e-05 25.3 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 KPI36031.1 - 2.2e-05 23.9 0.0 4.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 KPI36031.1 - 8.1e-05 23.4 0.0 0.00034 21.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain Birna_VP4 PF01768.11 KPI36031.1 - 0.0002 20.4 0.0 0.00036 19.6 0.0 1.4 1 0 0 1 1 1 1 Birnavirus VP4 protein TIP49 PF06068.8 KPI36031.1 - 0.00034 19.4 0.0 0.00058 18.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 KPI36031.1 - 0.00035 20.7 0.0 0.003 17.7 0.0 2.6 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KPI36031.1 - 0.00061 18.9 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 KPI36031.1 - 0.00088 18.8 0.0 0.0024 17.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KPI36031.1 - 0.0015 17.9 0.0 0.0041 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KPI36031.1 - 0.002 17.8 0.0 0.0086 15.8 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KPI36031.1 - 0.0044 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KPI36031.1 - 0.0072 16.2 0.0 0.024 14.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KPI36031.1 - 0.011 15.6 0.0 0.031 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KPI36031.1 - 0.014 15.0 0.1 0.057 13.0 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 KPI36031.1 - 0.016 14.2 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KPI36031.1 - 0.02 15.1 0.1 0.066 13.5 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KPI36031.1 - 0.028 14.7 0.0 0.028 14.7 0.0 3.0 2 1 0 2 2 1 0 AAA domain AAA_24 PF13479.1 KPI36031.1 - 0.031 13.8 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KPI36031.1 - 0.055 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 KPI36031.1 - 0.055 12.8 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 KPI36031.1 - 0.058 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 UPF0079 PF02367.12 KPI36031.1 - 0.058 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 KPI36031.1 - 0.079 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 KPI36031.1 - 0.091 13.0 0.9 0.46 10.7 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_PrkA PF08298.6 KPI36031.1 - 0.098 11.3 0.1 1.2 7.7 0.1 2.1 2 0 0 2 2 2 0 PrkA AAA domain Mg_chelatase PF01078.16 KPI36031.1 - 0.1 11.7 0.1 0.22 10.6 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FlxA PF14282.1 KPI36031.1 - 1.5 8.8 4.8 2.1 8.3 2.1 2.1 2 0 0 2 2 1 0 FlxA-like protein zf-RING_2 PF13639.1 KPI36032.1 - 2.1e-08 33.8 7.5 4.4e-08 32.8 5.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KPI36032.1 - 0.00051 20.0 8.7 0.0011 18.9 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI36032.1 - 0.00067 19.2 9.3 0.0014 18.2 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KPI36032.1 - 0.00082 18.9 6.7 0.0029 17.2 4.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI36032.1 - 0.0046 16.6 8.4 0.0046 16.6 5.8 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 KPI36032.1 - 0.016 15.3 5.7 0.047 13.8 4.0 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 KPI36032.1 - 0.017 14.9 1.4 0.03 14.1 1.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KPI36032.1 - 0.078 12.5 8.4 0.2 11.2 5.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.7 KPI36032.1 - 0.25 11.5 2.4 2.6 8.2 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KPI36032.1 - 0.27 11.6 2.5 13 6.3 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Prp19_bind PF06991.6 KPI36033.1 - 1.2e-31 110.0 17.6 1.2e-31 110.0 12.2 2.7 2 1 0 2 2 2 1 Splicing factor, Prp19-binding domain FAM75 PF14650.1 KPI36033.1 - 0.038 13.3 5.3 0.071 12.4 3.7 1.4 1 0 0 1 1 1 0 FAM75 family Y2_Tnp PF04986.8 KPI36033.1 - 0.14 11.8 0.6 0.26 11.0 0.4 1.3 1 0 0 1 1 1 0 Putative transposase NAD_binding_2 PF03446.10 KPI36034.1 - 6.4e-27 94.3 0.1 9.3e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KPI36034.1 - 8.4e-11 42.0 0.1 1.5e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KPI36034.1 - 2.5e-05 24.6 0.0 8.6e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent SNF PF00209.13 KPI36036.1 - 1.2e-70 238.4 35.9 3.6e-49 167.6 10.8 2.8 3 0 0 3 3 3 2 Sodium:neurotransmitter symporter family DUF3810 PF12725.2 KPI36036.1 - 0.18 10.6 0.3 0.35 9.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Fungal_trans_2 PF11951.3 KPI36037.1 - 5.1e-08 31.9 11.7 4.9e-05 22.0 3.1 3.5 3 1 0 3 3 3 2 Fungal specific transcription factor domain COesterase PF00135.23 KPI36038.1 - 1.6e-65 221.8 0.0 4.5e-65 220.3 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI36038.1 - 1.1e-07 31.7 0.1 4.8e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold CAP59_mtransfer PF11735.3 KPI36039.1 - 4.1e-55 186.6 0.0 8e-55 185.6 0.0 1.4 1 1 0 1 1 1 1 Cryptococcal mannosyltransferase 1 RabGAP-TBC PF00566.13 KPI36040.1 - 7.1e-33 113.8 0.0 2.2e-32 112.2 0.0 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain YjeF_N PF03853.10 KPI36041.1 - 9.2e-31 106.7 0.2 1.4e-30 106.1 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 KPI36041.1 - 2.4e-07 31.2 0.7 5.9e-07 29.9 0.5 1.7 1 0 0 1 1 1 1 FDF domain zf-RING_2 PF13639.1 KPI36042.1 - 5.5e-10 38.9 4.2 1.3e-08 34.4 0.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KPI36042.1 - 1.2e-06 28.4 3.7 8.8e-06 25.7 2.5 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KPI36042.1 - 3e-06 26.8 1.4 4.9e-06 26.1 0.1 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KPI36042.1 - 9.5e-06 25.2 3.3 1.4e-05 24.6 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI36042.1 - 3.3e-05 23.4 1.9 0.00013 21.4 1.3 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI36042.1 - 0.00012 22.0 1.0 0.00012 22.0 0.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PQ-loop PF04193.9 KPI36042.1 - 0.00058 19.3 0.3 0.0019 17.7 0.2 1.9 1 0 0 1 1 1 1 PQ loop repeat zf-Apc11 PF12861.2 KPI36042.1 - 0.0069 16.2 0.4 0.015 15.1 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KPI36042.1 - 0.072 12.8 1.6 0.21 11.3 0.3 2.4 1 1 1 2 2 2 0 RING-type zinc-finger LCM PF04072.9 KPI36043.1 - 1.5e-22 80.0 0.0 2.4e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Cupin_8 PF13621.1 KPI36043.1 - 6.6e-20 71.6 0.0 3.6e-19 69.2 0.0 2.0 2 0 0 2 2 2 1 Cupin-like domain Kelch_4 PF13418.1 KPI36043.1 - 2.9e-08 33.3 3.8 2.7e-05 23.8 0.1 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 KPI36043.1 - 0.00019 21.5 6.5 0.0047 17.0 0.1 4.5 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 KPI36043.1 - 0.013 15.4 0.1 0.47 10.4 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 KPI36043.1 - 0.038 13.7 0.3 21 5.1 0.0 3.7 3 0 0 3 3 3 0 Kelch motif Fungal_trans PF04082.13 KPI36045.1 - 2.5e-17 62.6 1.6 3.9e-17 61.9 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF_assoc_1 PF08355.7 KPI36045.1 - 0.076 12.3 0.7 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 EF hand associated ADIP PF11559.3 KPI36046.1 - 0.011 15.6 15.1 0.29 11.0 3.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HD_3 PF13023.1 KPI36046.1 - 0.059 13.1 1.4 0.097 12.4 1.0 1.3 1 0 0 1 1 1 0 HD domain CENP-F_leu_zip PF10473.4 KPI36046.1 - 0.1 12.4 15.4 0.37 10.6 10.6 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 KPI36046.1 - 0.14 11.5 13.1 0.25 10.7 9.0 1.3 1 1 0 1 1 1 0 Intermediate filament protein CorA PF01544.13 KPI36046.1 - 0.47 9.4 4.4 0.79 8.6 3.0 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DegS PF05384.6 KPI36046.1 - 0.72 9.0 10.6 2.6 7.2 1.3 2.2 1 1 1 2 2 2 0 Sensor protein DegS APG6 PF04111.7 KPI36046.1 - 0.8 8.6 16.4 0.58 9.1 1.0 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 ERM PF00769.14 KPI36046.1 - 1 8.8 15.9 1.9 7.9 11.0 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Snapin_Pallidin PF14712.1 KPI36046.1 - 1.3 9.4 10.2 6.9 7.0 0.6 3.0 1 1 1 2 2 2 0 Snapin/Pallidin Mt_ATP-synt_B PF05405.9 KPI36046.1 - 2.5 7.5 6.0 2.7 7.4 1.6 2.0 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DivIVA PF05103.8 KPI36046.1 - 3.6 7.6 10.0 0.31 11.0 0.8 2.1 2 0 0 2 2 2 0 DivIVA protein DUF4201 PF13870.1 KPI36046.1 - 4.3 6.7 13.9 6.7 6.1 1.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF972 PF06156.8 KPI36046.1 - 5 7.5 12.4 4.8 7.5 3.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CALCOCO1 PF07888.6 KPI36046.1 - 8.2 4.5 13.5 18 3.4 9.4 1.5 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Syntaxin-6_N PF09177.6 KPI36046.1 - 9.2 6.7 7.9 1.2 9.5 0.5 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CHRD PF07452.7 KPI36047.1 - 6.6e-05 23.5 0.0 0.00012 22.6 0.0 1.5 1 1 0 1 1 1 1 CHRD domain UCH PF00443.24 KPI36048.1 - 1.8e-31 109.2 0.0 3.3e-31 108.3 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KPI36048.1 - 2.6e-09 36.9 0.1 5.6e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Octopine_DH PF02317.12 KPI36048.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain GFO_IDH_MocA PF01408.17 KPI36049.1 - 1.4e-13 51.3 0.0 7.3e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Glyco_trans_4_2 PF13477.1 KPI36049.1 - 0.18 11.6 0.1 9.9 5.9 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase 4-like MFS_1 PF07690.11 KPI36050.1 - 2.3e-31 108.7 37.4 2.3e-31 108.7 25.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily IF4E PF01652.13 KPI36051.1 - 9.3e-28 96.8 0.0 1.3e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E GTP_EFTU PF00009.22 KPI36053.1 - 2.4e-60 203.2 0.2 3.3e-60 202.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KPI36053.1 - 2.4e-19 69.3 0.1 7.1e-19 67.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KPI36053.1 - 3.4e-19 68.7 1.6 9.6e-19 67.2 1.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KPI36053.1 - 2.1e-05 24.4 0.0 4.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KPI36053.1 - 0.0034 16.9 0.3 0.015 14.9 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Miro PF08477.8 KPI36053.1 - 0.0035 17.8 0.0 0.0063 17.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KPI36053.1 - 0.013 14.9 0.2 3.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 KPI36053.1 - 0.042 12.9 0.2 0.22 10.6 0.1 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region cobW PF02492.14 KPI36053.1 - 0.077 12.4 0.3 0.43 10.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Hepatitis_core PF00906.15 KPI36053.1 - 0.17 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Hepatitis core antigen Sugar_tr PF00083.19 KPI36054.1 - 4.3e-75 253.0 22.6 5e-75 252.8 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI36054.1 - 2.3e-27 95.6 32.0 1.1e-23 83.4 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.10 KPI36054.1 - 2.4 7.8 11.9 0.08 12.6 2.6 2.7 2 0 0 2 2 2 0 Glycine zipper 2TM domain Cation_efflux PF01545.16 KPI36057.1 - 4.3e-29 101.4 4.5 6.1e-29 100.9 3.1 1.1 1 0 0 1 1 1 1 Cation efflux family NAD_binding_10 PF13460.1 KPI36058.1 - 4.5e-10 39.8 0.1 1.2e-09 38.4 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI36058.1 - 3e-05 23.5 0.0 8.5e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KPI36058.1 - 0.00061 18.8 0.0 0.00084 18.4 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 KPI36058.1 - 0.0012 17.8 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 KPI36058.1 - 0.0018 18.5 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KPI36058.1 - 0.0044 16.3 0.1 0.0068 15.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Ldh_1_N PF00056.18 KPI36058.1 - 0.023 14.5 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain KR PF08659.5 KPI36058.1 - 0.045 13.4 0.1 0.065 12.8 0.1 1.2 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.10 KPI36058.1 - 0.069 12.0 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein IPK PF03770.11 KPI36059.1 - 8.1e-57 192.0 0.0 1.4e-56 191.2 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.5 KPI36059.1 - 0.014 15.1 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 zf-RING_2 PF13639.1 KPI36060.1 - 2.7e-10 39.8 4.2 8e-10 38.3 2.9 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KPI36060.1 - 1.8e-07 30.6 1.6 1.8e-07 30.6 1.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI36060.1 - 3.3e-06 26.6 4.7 9.1e-06 25.2 3.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI36060.1 - 4.7e-06 26.5 4.7 4.7e-06 26.5 3.3 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KPI36060.1 - 4.4e-05 23.5 4.0 0.00018 21.5 2.8 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KPI36060.1 - 5.3e-05 22.8 3.3 5.3e-05 22.8 2.3 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KPI36060.1 - 0.058 13.2 2.4 0.2 11.4 1.7 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KPI36060.1 - 0.093 12.3 4.6 0.25 10.9 3.2 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-H2C2_2 PF13465.1 KPI36060.1 - 0.82 10.0 5.0 1.6 9.1 1.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 KPI36060.1 - 7.3 7.1 6.9 4 7.9 0.1 3.4 5 0 0 5 5 5 0 Zinc finger, C2H2 type Beta-lactamase PF00144.19 KPI36061.1 - 9.2e-21 74.1 0.6 6e-20 71.5 0.4 2.3 1 1 0 1 1 1 1 Beta-lactamase DUF1669 PF07894.7 KPI36061.1 - 6.9 5.7 7.7 0.26 10.4 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1669) FlaC_arch PF05377.6 KPI36063.1 - 0.018 14.9 1.5 9.5 6.2 0.1 3.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 KPI36063.1 - 0.086 13.2 33.7 0.14 12.5 3.5 5.0 1 1 4 5 5 5 0 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 KPI36063.1 - 0.27 11.0 41.6 0.83 9.5 4.2 4.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 KPI36063.1 - 1.7 8.5 46.0 8.2 6.3 5.4 4.7 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding DUF648 PF04890.8 KPI36063.1 - 2.3 7.3 12.3 0.061 12.4 2.3 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF648) DUF842 PF05811.8 KPI36063.1 - 6.3 6.2 14.9 0.33 10.4 3.1 3.0 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF842) CALCOCO1 PF07888.6 KPI36063.1 - 7 4.8 39.1 0.17 10.1 7.3 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fapy_DNA_glyco PF01149.19 KPI36064.1 - 2.6e-22 79.3 0.0 7.6e-22 77.8 0.0 1.8 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 KPI36064.1 - 2.1e-16 59.4 0.0 4.8e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FAD_binding_4 PF01565.18 KPI36065.1 - 2.2e-19 69.2 0.0 3.5e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain UPF0128 PF03673.8 KPI36065.1 - 0.019 14.2 0.1 0.31 10.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0128) DUF1965 PF09248.5 KPI36065.1 - 0.057 13.3 1.2 0.19 11.6 0.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1965) HAD_2 PF13419.1 KPI36066.1 - 4.7e-14 52.9 0.0 4.4e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KPI36066.1 - 1.3e-06 29.0 0.0 1.7e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KPI36066.1 - 3.6e-05 23.3 0.0 0.00015 21.4 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 KPI36066.1 - 0.056 13.3 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Ribosomal_S6 PF01250.12 KPI36067.1 - 1.2e-05 25.0 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 DUF444 PF04285.7 KPI36067.1 - 0.098 11.2 0.2 0.12 11.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF444) SnoaL_4 PF13577.1 KPI36068.1 - 0.1 12.5 1.0 0.46 10.4 0.7 2.0 1 1 0 1 1 1 0 SnoaL-like domain SNF2_N PF00176.18 KPI36069.1 - 3.9e-55 186.7 0.2 5.5e-55 186.2 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KPI36069.1 - 2e-10 40.3 0.0 5.8e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 KPI36069.1 - 7.1e-05 22.4 6.8 0.00012 21.7 4.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KPI36069.1 - 0.0027 17.3 5.9 0.005 16.4 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI36069.1 - 0.0032 17.4 9.2 0.0066 16.4 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KPI36069.1 - 0.011 15.3 7.7 0.02 14.5 5.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KPI36069.1 - 0.012 15.3 5.4 0.032 13.9 3.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 KPI36069.1 - 0.086 12.6 8.0 0.2 11.4 5.5 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 KPI36069.1 - 0.18 11.6 11.6 0.37 10.7 8.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ADH_N PF08240.7 KPI36070.1 - 4.5e-28 97.1 0.4 7.8e-28 96.4 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 KPI36070.1 - 3.8e-11 42.4 0.5 9.5e-11 41.1 0.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 KPI36070.1 - 1.5e-05 24.5 0.4 3.7e-05 23.2 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase IF3_C PF00707.17 KPI36071.1 - 9.3e-10 38.1 2.5 1.6e-09 37.3 1.8 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 KPI36071.1 - 3.8e-05 23.1 3.6 5.6e-05 22.5 2.5 1.2 1 0 0 1 1 1 1 Mitochondrial translation initiation factor DUF724 PF05266.9 KPI36071.1 - 0.87 9.1 7.9 1.4 8.4 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Siah-Interact_N PF09032.6 KPI36071.1 - 3.9 7.5 10.2 7.7 6.6 2.3 2.6 2 0 0 2 2 2 0 Siah interacting protein, N terminal GFA PF04828.9 KPI36072.1 - 1.3e-09 37.8 0.0 3.2e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KPI36072.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DUF1610 PF07754.6 KPI36072.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) zinc_ribbon_2 PF13240.1 KPI36072.1 - 0.11 12.0 0.2 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain PC_rep PF01851.17 KPI36073.1 - 2.2e-20 71.6 10.1 2.5e-05 24.2 0.1 7.9 7 0 0 7 7 7 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KPI36073.1 - 0.00052 20.2 4.5 1.3 9.3 0.0 4.8 5 2 0 5 5 5 2 HEAT repeats AAA_2 PF07724.9 KPI36073.1 - 0.026 14.4 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) PQ-loop PF04193.9 KPI36074.1 - 1.7e-36 123.5 12.2 5.5e-18 64.2 1.8 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 KPI36074.1 - 3.4 7.5 9.4 1.5 8.7 0.2 2.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Fungal_trans PF04082.13 KPI36075.1 - 1.3e-24 86.5 1.0 2.2e-24 85.7 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KPI36075.1 - 1.8e-06 27.9 15.3 0.0014 18.8 1.8 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KPI36075.1 - 0.00014 21.9 6.3 0.00014 21.9 4.4 3.4 3 0 0 3 3 3 2 Zinc-finger double domain SBBP PF06739.6 KPI36075.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Beta-propeller repeat zf-C2H2_4 PF13894.1 KPI36075.1 - 0.42 11.0 21.7 0.32 11.4 2.3 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger DUF3608 PF12257.3 KPI36076.1 - 1.2e-73 247.4 0.1 1.7e-73 247.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 KPI36076.1 - 1.5e-26 91.9 0.7 4.5e-26 90.3 0.1 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase PF00069.20 KPI36077.1 - 6.9e-17 61.4 0.1 2.1e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain WD40 PF00400.27 KPI36077.1 - 2e-11 43.2 15.1 8.9e-09 34.9 0.2 5.2 4 0 0 4 4 4 3 WD domain, G-beta repeat HEAT PF02985.17 KPI36077.1 - 5.4e-08 32.2 6.9 0.047 13.7 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 KPI36077.1 - 5.5e-08 32.9 2.5 0.042 14.1 0.0 4.1 1 1 1 3 3 3 3 HEAT repeats HEAT_EZ PF13513.1 KPI36077.1 - 0.056 13.9 1.7 1 9.9 0.1 3.5 4 0 0 4 4 4 0 HEAT-like repeat Pkinase_Tyr PF07714.12 KPI36077.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase POT1 PF02765.12 KPI36080.1 - 4e-10 39.7 0.0 1.3e-09 38.0 0.0 1.9 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 CinA PF02464.12 KPI36080.1 - 0.057 12.8 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Competence-damaged protein TraV PF09676.5 KPI36080.1 - 0.89 10.2 7.4 0.28 11.9 2.0 2.4 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) RVT_1 PF00078.22 KPI36081.1 - 0.035 13.4 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TcpE PF12648.2 KPI36081.1 - 0.22 11.6 1.8 0.22 11.6 0.4 1.7 2 0 0 2 2 2 0 TcpE family Sugar_tr PF00083.19 KPI36082.1 - 9.3e-86 288.1 23.8 1.1e-85 287.9 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI36082.1 - 3.5e-26 91.7 62.0 5.2e-23 81.3 21.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI36082.1 - 4.4e-05 22.0 25.1 0.0015 16.9 4.1 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 KPI36082.1 - 5e-05 21.7 1.7 5e-05 21.7 1.2 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KPI36082.1 - 1.8 6.5 12.2 1.1 7.1 0.8 3.6 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Phosphonate-bd PF12974.2 KPI36083.1 - 1.2e-17 64.1 0.1 1.9e-17 63.4 0.1 1.5 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.15 KPI36083.1 - 0.029 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 DUF3328 PF11807.3 KPI36084.1 - 2.4e-24 86.2 0.1 3.1e-24 85.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) FNIP_N PF14636.1 KPI36085.1 - 3.1e-10 40.6 0.3 3.1e-10 40.6 0.2 3.8 4 0 0 4 4 4 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 KPI36085.1 - 0.001 18.7 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain Peptidase_C97 PF05903.9 KPI36086.1 - 1e-38 132.4 0.0 1.8e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 KPI36086.1 - 5.3e-16 58.2 1.9 1.9e-07 30.1 1.0 2.3 1 1 1 2 2 2 2 PUL domain Thioredoxin PF00085.15 KPI36086.1 - 0.015 15.0 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.1 KPI36086.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Epimerase PF01370.16 KPI36088.1 - 2.9e-17 62.9 0.1 1.4e-16 60.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI36088.1 - 6.6e-12 45.7 0.2 1.5e-11 44.6 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KPI36088.1 - 4.6e-11 41.9 0.0 6.3e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KPI36088.1 - 8.5e-05 21.9 0.3 0.00014 21.1 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KPI36088.1 - 0.00041 20.3 0.1 0.0027 17.6 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KPI36088.1 - 0.0012 17.7 0.0 0.0017 17.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KPI36088.1 - 0.0013 17.6 0.0 0.0033 16.3 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein CFEM PF05730.6 KPI36089.1 - 1.7e-16 59.7 7.1 1.7e-16 59.7 4.9 1.7 2 0 0 2 2 2 1 CFEM domain Fungal_trans PF04082.13 KPI36089.1 - 4.2e-07 29.1 0.1 1.8e-06 27.0 0.0 2.0 1 1 0 2 2 2 1 Fungal specific transcription factor domain Na_H_Exchanger PF00999.16 KPI36090.1 - 1.5e-68 231.1 14.0 1.7e-68 230.8 9.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.5 KPI36090.1 - 2.5e-53 181.9 44.6 1e-52 179.8 30.9 1.9 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus YrhC PF14143.1 KPI36090.1 - 0.15 12.0 1.4 0.36 10.8 0.1 2.2 2 0 0 2 2 2 0 YrhC-like protein DUF21 PF01595.15 KPI36090.1 - 0.18 11.0 3.8 0.52 9.5 2.6 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF21 DUF4190 PF13828.1 KPI36090.1 - 0.24 10.9 6.4 0.18 11.3 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) PRP4 PF08799.6 KPI36090.1 - 0.62 9.3 3.6 0.73 9.1 0.6 2.5 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like Fungal_trans_2 PF11951.3 KPI36091.1 - 7.3e-07 28.1 0.0 1.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.23 KPI36093.1 - 3.4e-78 262.9 0.0 4.6e-78 262.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KPI36093.1 - 1.3e-58 197.8 0.0 3.8e-58 196.3 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 KPI36093.1 - 3.8e-19 69.2 3.8 1.1e-08 35.2 1.4 3.8 2 1 1 3 3 3 3 short chain dehydrogenase PP-binding PF00550.20 KPI36093.1 - 2.8e-12 46.6 0.0 6.5e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 KPI36093.1 - 4.1e-12 46.0 0.1 2.3e-10 40.3 0.0 3.4 4 1 0 4 4 4 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KPI36093.1 - 1.9e-09 37.4 2.4 8.9e-06 25.4 0.4 3.5 2 1 1 3 3 3 2 KR domain adh_short_C2 PF13561.1 KPI36093.1 - 4.9e-09 36.3 4.2 3.9e-05 23.5 0.0 2.9 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 KPI36093.1 - 3.2e-08 32.6 0.1 1.2e-05 24.1 0.0 2.5 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KPI36093.1 - 1.9e-06 27.0 0.0 1.9e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 RmlD substrate binding domain AMP-binding_C PF13193.1 KPI36093.1 - 6.9e-05 23.7 1.5 0.00018 22.3 0.1 2.5 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 KPI36093.1 - 0.0041 16.0 1.8 0.43 9.4 0.3 3.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Arm PF00514.18 KPI36094.1 - 7.9e-91 295.1 12.7 1.7e-13 49.8 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KPI36094.1 - 3.8e-24 84.7 1.0 9.5e-10 38.6 0.0 5.7 1 1 6 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 KPI36094.1 - 4.2e-21 74.8 4.7 8.6e-09 35.6 0.1 5.9 3 1 3 6 6 6 3 HEAT-like repeat IBB PF01749.15 KPI36094.1 - 3.4e-19 68.7 2.7 6.3e-19 67.9 1.9 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 KPI36094.1 - 2.3e-18 64.5 0.0 7.5e-06 25.6 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat Arm_2 PF04826.8 KPI36094.1 - 1.1e-09 37.7 0.0 0.009 15.1 0.0 4.0 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 KPI36094.1 - 1.2e-05 23.8 0.0 0.00025 19.4 0.0 2.4 1 1 0 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 KPI36094.1 - 0.00022 21.1 0.0 1.6 8.6 0.0 4.5 3 1 0 4 4 4 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 KPI36094.1 - 0.00083 17.7 0.0 0.27 9.4 0.0 3.1 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 KPI36094.1 - 0.013 15.9 4.9 0.84 10.2 0.0 4.4 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Glycos_trans_3N PF02885.12 KPI36094.1 - 0.023 14.2 0.0 39 3.9 0.0 3.7 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain DUF749 PF05370.6 KPI36094.1 - 0.12 12.2 0.3 0.56 10.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF749) Beta-lactamase PF00144.19 KPI36095.1 - 1.6e-13 50.4 0.0 1.7e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Acyltransferase PF01553.16 KPI36097.1 - 2.6e-17 62.5 0.0 6.1e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase GDA1_CD39 PF01150.12 KPI36098.1 - 1.4e-92 310.5 0.0 1.8e-92 310.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family zf-RING_2 PF13639.1 KPI36099.1 - 4.1e-06 26.5 9.3 4.1e-06 26.5 6.4 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KPI36099.1 - 0.00011 21.7 6.1 0.00027 20.5 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI36099.1 - 0.00022 21.1 9.1 0.00045 20.1 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI36099.1 - 0.0012 18.5 10.1 0.0022 17.6 7.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KPI36099.1 - 0.0013 18.3 9.5 0.0022 17.5 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KPI36099.1 - 0.0078 16.2 6.4 0.024 14.7 4.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger DUF2368 PF10166.4 KPI36099.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) zf-Apc11 PF12861.2 KPI36099.1 - 1.3 8.9 6.6 7.3 6.5 4.6 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KPI36099.1 - 2.2 7.9 13.0 2.8 7.5 5.8 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.24 KPI36099.1 - 6.7 6.4 10.1 18 5.0 7.0 1.8 1 0 0 1 1 1 0 PHD-finger TRAPP PF04051.11 KPI36100.1 - 4.4e-28 97.7 0.0 5.4e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component zf-RING_2 PF13639.1 KPI36101.1 - 3.1e-11 42.9 5.4 4.8e-11 42.3 3.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KPI36101.1 - 1e-06 28.6 3.0 1.6e-06 28.0 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KPI36101.1 - 1.2e-06 28.5 5.1 2.3e-06 27.6 3.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KPI36101.1 - 7.4e-06 25.5 2.9 1.2e-05 24.9 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI36101.1 - 1.3e-05 24.8 3.5 2e-05 24.2 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KPI36101.1 - 1.7e-05 24.3 0.5 2.9e-05 23.6 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Bcr-Abl_Oligo PF09036.5 KPI36101.1 - 0.0013 18.6 0.4 0.0013 18.6 0.3 1.8 2 0 0 2 2 2 1 Bcr-Abl oncoprotein oligomerisation domain zf-RING_4 PF14570.1 KPI36101.1 - 0.003 17.1 1.0 0.0047 16.4 0.7 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KPI36101.1 - 0.011 15.3 2.7 0.014 15.0 0.7 2.0 2 0 0 2 2 2 0 RING-type zinc-finger Mnd1 PF03962.10 KPI36101.1 - 0.04 13.5 4.8 0.058 13.0 3.3 1.2 1 0 0 1 1 1 0 Mnd1 family Striatin PF08232.7 KPI36101.1 - 0.042 14.1 5.5 0.062 13.6 3.8 1.2 1 0 0 1 1 1 0 Striatin family Macoilin PF09726.4 KPI36101.1 - 0.087 11.1 4.5 0.11 10.7 3.1 1.1 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 KPI36101.1 - 0.35 10.4 4.3 0.5 9.9 3.0 1.2 1 0 0 1 1 1 0 IncA protein zf-C4H2 PF10146.4 KPI36101.1 - 0.39 10.6 4.1 0.51 10.3 2.8 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein zf-Apc11 PF12861.2 KPI36101.1 - 4.4 7.2 6.4 17 5.3 4.5 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PspB PF06667.7 KPI36101.1 - 7 6.6 8.5 8.9 6.3 0.6 3.2 2 2 1 3 3 3 0 Phage shock protein B bZIP_1 PF00170.16 KPI36102.1 - 6.5e-07 29.2 7.3 1.1e-06 28.4 5.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor Hira PF07569.6 KPI36102.1 - 0.001 18.3 0.1 0.0014 17.8 0.1 1.1 1 0 0 1 1 1 1 TUP1-like enhancer of split CAF-1_p150 PF11600.3 KPI36102.1 - 0.029 13.7 0.6 0.036 13.4 0.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal bZIP_2 PF07716.10 KPI36102.1 - 0.071 12.9 10.8 0.14 11.9 7.5 1.5 1 1 0 1 1 1 0 Basic region leucine zipper GvpL_GvpF PF06386.6 KPI36102.1 - 0.16 11.5 1.0 0.26 10.8 0.7 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_Maf PF03131.12 KPI36102.1 - 1.6 9.0 11.9 4.3 7.6 8.2 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor adh_short PF00106.20 KPI36103.1 - 1.2e-20 74.1 1.8 1.6e-20 73.6 0.2 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI36103.1 - 1e-09 38.5 0.2 1.8e-09 37.7 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI36103.1 - 9e-09 35.2 0.1 1.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI36103.1 - 0.00027 20.4 0.1 0.00046 19.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI36103.1 - 0.00054 20.0 0.5 0.0022 18.0 0.3 2.0 1 1 0 1 1 1 1 NADH(P)-binding Thi4 PF01946.12 KPI36103.1 - 0.018 14.1 0.1 0.029 13.4 0.1 1.2 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 KPI36103.1 - 0.044 13.4 0.1 0.076 12.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KPI36103.1 - 0.094 11.7 0.2 0.22 10.6 0.1 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TIR-like PF10137.4 KPI36103.1 - 0.1 12.2 0.2 0.23 11.1 0.1 1.6 2 0 0 2 2 2 0 Predicted nucleotide-binding protein containing TIR-like domain CW_binding_2 PF04122.7 KPI36103.1 - 0.11 12.7 0.2 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 NmrA PF05368.8 KPI36103.1 - 0.11 11.7 0.2 0.31 10.2 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family Shikimate_DH PF01488.15 KPI36103.1 - 0.12 12.4 0.4 0.97 9.5 0.3 2.1 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3176 PF11374.3 KPI36104.1 - 4.1e-32 110.3 0.4 9.1e-32 109.2 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Abhydrolase_3 PF07859.8 KPI36105.1 - 8.4e-36 123.5 0.0 1.1e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KPI36105.1 - 0.025 13.3 0.0 0.042 12.5 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family HSP70 PF00012.15 KPI36106.1 - 4.3e-12 44.7 0.5 1.3e-10 39.8 0.0 2.9 3 1 0 3 3 3 2 Hsp70 protein DnaJ PF00226.26 KPI36107.1 - 1.8e-16 59.5 0.1 6.8e-16 57.7 0.1 2.1 1 0 0 1 1 1 1 DnaJ domain DUF2062 PF09835.4 KPI36108.1 - 0.048 13.2 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) ERG2_Sigma1R PF04622.7 KPI36108.1 - 0.11 11.8 0.0 0.21 10.8 0.0 1.5 1 1 0 1 1 1 0 ERG2 and Sigma1 receptor like protein MFS_1 PF07690.11 KPI36109.1 - 1.3e-23 83.2 17.8 1.3e-23 83.2 12.4 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KPI36109.1 - 9.8e-06 24.0 3.7 2e-05 23.0 2.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KPI36112.1 - 3.2e-19 68.8 22.4 5.2e-12 45.0 4.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Ribosomal_S19 PF00203.16 KPI36113.1 - 1.5e-33 114.2 0.2 2.1e-33 113.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 CDC73 PF05179.9 KPI36113.1 - 0.026 13.8 0.0 0.03 13.6 0.0 1.0 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family Cpn60_TCP1 PF00118.19 KPI36114.1 - 3.2e-140 467.9 10.5 4e-140 467.6 7.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 KPI36114.1 - 0.029 13.8 0.0 0.074 12.5 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X ADH_zinc_N PF00107.21 KPI36115.1 - 8e-24 83.6 0.1 1.4e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI36115.1 - 1.2e-19 70.0 0.8 2.2e-19 69.2 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KPI36115.1 - 8.8e-11 42.7 0.0 1.7e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_C9 PF01707.11 KPI36116.1 - 0.011 15.2 0.1 0.037 13.6 0.0 1.8 2 0 0 2 2 2 0 Peptidase family C9 Glyco_transf_20 PF00982.16 KPI36116.1 - 0.082 11.3 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 20 UCH PF00443.24 KPI36117.1 - 1.4e-66 224.4 0.1 2.2e-66 223.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KPI36117.1 - 2.6e-33 115.7 0.5 1.4e-25 90.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KPI36117.1 - 0.029 13.6 3.9 0.28 10.4 1.8 2.7 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase YSIRK_signal PF04650.12 KPI36117.1 - 0.2 11.2 2.5 0.4 10.2 1.7 1.5 1 0 0 1 1 1 0 YSIRK type signal peptide Mito_carr PF00153.22 KPI36118.1 - 2.6e-54 180.9 0.5 3.7e-20 71.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3147 PF11345.3 KPI36118.1 - 0.049 13.6 0.7 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) Beta-lactamase PF00144.19 KPI36120.1 - 1.8e-42 145.5 0.1 3.5e-42 144.6 0.1 1.4 2 0 0 2 2 2 1 Beta-lactamase DAP_C PF07932.7 KPI36120.1 - 4.5e-33 113.2 0.1 8.4e-33 112.4 0.1 1.5 1 0 0 1 1 1 1 D-aminopeptidase, domain C Aminotran_1_2 PF00155.16 KPI36122.1 - 1.8e-15 56.7 0.0 2.4e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KPI36122.1 - 0.0056 15.7 0.0 0.11 11.5 0.0 2.2 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF485 PF04341.7 KPI36125.1 - 0.63 9.7 7.0 0.3 10.8 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Metallophos PF00149.23 KPI36126.1 - 2.2e-08 33.7 0.9 1.2e-06 28.0 0.0 2.9 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase ADH_zinc_N PF00107.21 KPI36127.1 - 6.7e-25 87.1 0.0 1.3e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI36127.1 - 2.6e-20 73.5 0.0 5.3e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI36127.1 - 3.9e-07 29.7 0.0 7.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 KPI36127.1 - 0.024 13.7 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AMP-binding PF00501.23 KPI36129.1 - 2.1e-226 751.0 0.9 2.4e-81 273.3 0.1 4.2 3 1 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KPI36129.1 - 4.4e-112 373.8 0.7 4.8e-30 104.4 0.1 6.6 5 2 0 5 5 5 5 Condensation domain PP-binding PF00550.20 KPI36129.1 - 4.1e-32 110.2 0.5 4.1e-09 36.5 0.0 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KPI36129.1 - 1.3e-14 54.9 0.2 0.00032 21.5 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain PE_PPE_C PF12484.3 KPI36131.1 - 6.4 7.7 8.7 6.1 7.8 1.9 2.1 2 0 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal MFS_1 PF07690.11 KPI36132.1 - 1.6e-31 109.3 27.3 1.6e-31 109.3 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyrophosphatase PF00719.14 KPI36133.1 - 1.9e-52 176.8 0.1 2.4e-52 176.4 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Sugar_tr PF00083.19 KPI36135.1 - 1.5e-102 343.5 26.3 1.7e-102 343.3 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI36135.1 - 1.7e-25 89.4 55.6 2e-23 82.7 18.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EF-hand_6 PF13405.1 KPI36136.1 - 7.3e-14 50.3 2.4 2.2e-05 23.9 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 KPI36136.1 - 5.2e-12 44.1 5.0 3.6e-06 25.8 0.0 4.6 4 1 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 KPI36136.1 - 1.1e-10 41.4 0.3 3.4e-09 36.7 0.2 2.7 2 2 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KPI36136.1 - 1.5e-06 27.2 7.4 0.00072 18.7 0.2 3.4 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KPI36136.1 - 4.2e-06 26.2 1.9 0.0032 17.0 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair Sec20 PF03908.8 KPI36137.1 - 6.5e-16 57.8 0.5 1.4e-15 56.7 0.0 1.8 2 0 0 2 2 2 1 Sec20 2TM PF13239.1 KPI36137.1 - 1.5 8.9 5.7 3.5 7.7 4.0 1.5 1 0 0 1 1 1 0 2TM domain DUF4230 PF14014.1 KPI36137.1 - 5 6.9 8.8 0.071 12.9 0.6 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4230) MIF4G PF02854.14 KPI36138.1 - 1.3e-27 96.5 2.3 2e-27 95.9 0.3 2.1 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 KPI36138.1 - 3e-25 88.1 0.1 2.1e-24 85.3 0.0 2.5 2 0 0 2 2 2 1 MA3 domain Pyr_redox_3 PF13738.1 KPI36139.1 - 1.2e-19 71.1 0.0 2.2e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI36139.1 - 2.5e-06 27.5 0.0 6.3e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI36139.1 - 8.2e-06 24.9 0.0 1.8e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KPI36139.1 - 0.0014 18.4 0.0 0.0093 15.7 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thioredoxin_4 PF13462.1 KPI36141.1 - 9.3e-10 38.7 0.0 3.4e-09 36.9 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin Alpha-amylase PF00128.19 KPI36142.1 - 1.5e-64 218.4 0.0 2.2e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 KPI36142.1 - 6.4e-05 20.9 0.1 0.0016 16.3 0.1 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 70 DUF187 PF02638.10 KPI36142.1 - 0.011 14.6 0.1 0.021 13.6 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 hDGE_amylase PF14701.1 KPI36142.1 - 0.017 14.0 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme adh_short PF00106.20 KPI36143.1 - 9e-19 67.9 0.4 1.2e-18 67.5 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI36143.1 - 1.1e-07 31.9 0.0 1.4e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI36143.1 - 2.2e-06 27.4 0.4 3.5e-06 26.8 0.3 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI36143.1 - 0.028 14.4 0.2 0.052 13.5 0.2 1.5 1 0 0 1 1 1 0 NADH(P)-binding RmlD_sub_bind PF04321.12 KPI36143.1 - 0.034 13.0 0.1 0.1 11.4 0.1 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KPI36143.1 - 0.04 12.8 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KPI36143.1 - 0.064 13.0 0.3 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KPI36143.1 - 0.068 12.2 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Glyco_hydro_12 PF01670.11 KPI36144.1 - 3.5e-14 52.8 1.7 6.3e-14 52.0 1.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Peptidase_S10 PF00450.17 KPI36145.1 - 2.2e-79 267.5 8.0 5.1e-79 266.3 5.6 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase UDPG_MGDP_dh_C PF03720.10 KPI36145.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ChaC PF04752.7 KPI36146.1 - 7e-53 179.2 0.0 8.6e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Cation_efflux PF01545.16 KPI36147.1 - 1.5e-76 257.1 6.6 5e-76 255.5 4.6 1.7 1 1 0 1 1 1 1 Cation efflux family Zip PF02535.17 KPI36147.1 - 0.25 10.3 15.2 6.3 5.7 10.5 2.2 1 1 0 1 1 1 0 ZIP Zinc transporter MgtE_N PF03448.12 KPI36148.1 - 0.079 13.2 0.2 0.17 12.2 0.0 1.7 2 0 0 2 2 2 0 MgtE intracellular N domain CPSase_L_D2 PF02786.12 KPI36149.1 - 9.9e-111 368.0 0.0 5e-84 280.8 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 KPI36149.1 - 1.4e-42 145.4 0.1 1.4e-25 90.0 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_D3 PF02787.14 KPI36149.1 - 2.9e-40 136.8 0.1 7.7e-40 135.4 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 KPI36149.1 - 4.4e-29 100.7 0.0 2e-16 60.0 0.0 3.8 2 1 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KPI36149.1 - 1.4e-22 79.8 0.0 1.1e-09 37.5 0.0 3.5 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KPI36149.1 - 3.3e-22 78.6 0.0 6.9e-10 38.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KPI36149.1 - 6.7e-19 68.0 0.2 1.6e-09 37.4 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 KPI36149.1 - 9.1e-10 38.3 0.0 6.5e-06 25.7 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KPI36149.1 - 6.1e-08 32.6 0.1 0.001 18.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KPI36149.1 - 1.7e-05 24.4 0.1 0.024 14.1 0.0 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 KPI36149.1 - 0.00029 20.1 0.1 0.081 12.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Epimerase PF01370.16 KPI36149.1 - 0.016 14.6 0.0 0.047 13.1 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family MGS PF02142.17 KPI36149.1 - 0.027 14.4 0.0 0.073 13.0 0.0 1.8 1 0 0 1 1 1 0 MGS-like domain Pkinase PF00069.20 KPI36151.1 - 4.2e-57 193.2 0.0 6.6e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI36151.1 - 7.8e-40 136.5 0.0 1.2e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI36151.1 - 5.7e-06 25.5 0.0 1.3e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KPI36151.1 - 0.0029 16.6 0.0 0.0058 15.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KPI36151.1 - 0.0049 16.6 0.1 0.0049 16.6 0.1 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 KPI36151.1 - 0.044 13.1 0.4 0.28 10.5 0.3 2.1 1 1 0 1 1 1 0 RIO1 family ATP_transf PF09830.4 KPI36152.1 - 1e-17 63.6 0.0 2.1e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase RCR PF12273.3 KPI36153.1 - 8.9e-22 78.0 13.5 1.3e-20 74.2 9.3 2.1 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.1 KPI36153.1 - 0.0032 17.6 0.1 0.012 15.8 0.0 1.8 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Rhabdo_glycop PF00974.13 KPI36153.1 - 0.0058 14.9 0.1 0.0078 14.4 0.1 1.1 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein GP41 PF00517.12 KPI36153.1 - 0.054 13.0 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein LysE PF01810.13 KPI36153.1 - 0.056 12.7 0.1 0.073 12.3 0.1 1.1 1 0 0 1 1 1 0 LysE type translocator Pentapeptide_2 PF01469.13 KPI36153.1 - 0.15 11.7 1.9 13 5.4 0.3 2.5 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) OSTMP1 PF09777.4 KPI36153.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor MRP_L53 PF10780.4 KPI36155.1 - 7e-11 41.9 0.1 1.2e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 TPR_11 PF13414.1 KPI36156.1 - 4e-07 29.5 4.7 0.00049 19.6 0.2 4.0 3 1 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 KPI36156.1 - 3.1e-05 24.5 7.0 0.11 13.1 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KPI36156.1 - 0.00037 20.7 2.7 2.4 8.5 0.0 4.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KPI36156.1 - 0.0038 17.3 0.1 0.88 9.9 0.0 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KPI36156.1 - 0.031 14.9 7.3 2.4 9.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KPI36156.1 - 0.047 13.6 7.3 0.56 10.1 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KPI36156.1 - 0.39 10.4 5.5 3.3 7.4 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KPI36156.1 - 0.4 10.7 8.9 11 6.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat APC_CDC26 PF10471.4 KPI36157.1 - 3e-12 47.1 4.8 6.7e-10 39.5 3.4 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 CBM_20 PF00686.14 KPI36158.1 - 1.7e-29 101.2 0.1 2.1e-29 100.9 0.1 1.1 1 0 0 1 1 1 1 Starch binding domain DUF3327 PF11806.3 KPI36158.1 - 0.026 14.8 0.0 0.027 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3327) Cu-oxidase_2 PF07731.9 KPI36158.1 - 0.054 13.0 0.1 0.072 12.5 0.1 1.3 1 0 0 1 1 1 0 Multicopper oxidase DUF2456 PF10445.4 KPI36159.1 - 0.0023 17.8 0.6 0.0035 17.2 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) KNOX1 PF03790.8 KPI36159.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 KNOX1 domain Cutinase PF01083.17 KPI36161.1 - 7e-51 172.4 0.0 8.6e-51 172.2 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KPI36161.1 - 0.004 16.6 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.3 KPI36161.1 - 0.006 15.9 0.0 0.0077 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) VirJ PF06057.6 KPI36161.1 - 0.15 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) NmrA PF05368.8 KPI36162.1 - 1e-34 119.8 0.0 1.7e-34 119.0 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI36162.1 - 1.2e-06 28.6 0.1 1.7e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI36162.1 - 0.00021 20.8 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KPI36162.1 - 0.0042 17.0 0.1 0.01 15.8 0.0 1.6 2 0 0 2 2 2 1 TrkA-N domain adh_short PF00106.20 KPI36162.1 - 0.0096 15.8 0.2 0.021 14.7 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KPI36162.1 - 0.041 12.5 0.0 0.062 11.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Met_10 PF02475.11 KPI36164.1 - 4.6e-61 205.9 0.0 7.3e-61 205.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KPI36164.1 - 0.061 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Condensation PF00668.15 KPI36165.1 - 2.7e-57 193.9 1.6 1.7e-32 112.4 0.0 4.2 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.20 KPI36165.1 - 2.4e-21 75.7 1.0 1.1e-09 38.3 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Synthase_beta PF11421.3 KPI36166.1 - 9.7 6.9 9.2 79 4.0 6.4 2.5 1 1 0 1 1 1 0 ATP synthase F1 beta subunit VSP PF03302.8 KPI36168.1 - 0.00036 19.2 1.1 0.00036 19.2 0.8 2.2 2 1 0 2 2 2 1 Giardia variant-specific surface protein Podoplanin PF05808.6 KPI36168.1 - 0.0021 17.6 0.4 0.0042 16.6 0.3 1.4 1 0 0 1 1 1 1 Podoplanin DUF1191 PF06697.7 KPI36168.1 - 0.0089 14.8 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Mid2 PF04478.7 KPI36168.1 - 0.031 13.6 0.3 0.059 12.7 0.2 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor HemY_N PF07219.8 KPI36168.1 - 0.059 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Sporozoite_P67 PF05642.6 KPI36168.1 - 3.8 5.2 11.4 4.8 4.9 7.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CTP_transf_2 PF01467.21 KPI36169.1 - 0.00095 19.2 0.0 0.01 15.9 0.0 2.1 2 0 0 2 2 2 1 Cytidylyltransferase RRM_1 PF00076.17 KPI36170.1 - 4.2e-23 80.7 0.1 6.5e-23 80.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI36170.1 - 2.2e-16 59.5 0.0 3.4e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI36170.1 - 2.2e-11 43.3 0.0 3.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HATPase_c PF02518.21 KPI36171.1 - 9.4e-29 99.3 0.1 1.7e-28 98.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KPI36171.1 - 1.8e-21 75.8 0.7 5.3e-21 74.3 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 KPI36171.1 - 1.5e-20 73.4 0.0 5.6e-11 42.7 0.0 4.5 4 0 0 4 4 4 2 PAS domain Response_reg PF00072.19 KPI36171.1 - 3.2e-19 68.9 0.1 1.1e-18 67.2 0.1 2.0 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.6 KPI36171.1 - 1.8e-16 60.0 0.2 9.7e-16 57.6 0.2 2.3 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 KPI36171.1 - 1.6e-12 47.3 0.2 1.5e-05 25.0 0.0 5.3 4 1 0 4 4 4 2 PAS fold PAS PF00989.19 KPI36171.1 - 3.9e-07 29.8 0.0 0.11 12.2 0.0 4.2 4 0 0 4 4 4 2 PAS fold PAS_10 PF13596.1 KPI36171.1 - 0.00079 19.6 0.0 0.46 10.7 0.0 2.9 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.1 KPI36171.1 - 0.022 14.6 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 0 PAS domain Tim17 PF02466.14 KPI36173.1 - 1.6e-25 89.6 0.6 3.1e-25 88.6 0.4 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Sulfotransfer_3 PF13469.1 KPI36174.1 - 0.034 15.0 2.8 0.18 12.7 2.0 2.3 1 1 0 1 1 1 0 Sulfotransferase family FAD_binding_2 PF00890.19 KPI36175.1 - 2.1e-112 376.0 7.7 4.7e-93 312.2 1.1 2.1 1 1 1 2 2 2 2 FAD binding domain Succ_DH_flav_C PF02910.15 KPI36175.1 - 6.7e-47 158.5 0.3 9.9e-47 158.0 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 KPI36175.1 - 1.3e-05 25.2 2.4 0.016 15.1 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI36175.1 - 6.2e-05 22.0 1.0 0.21 10.4 1.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 KPI36175.1 - 7.3e-05 21.9 0.2 0.023 13.7 0.0 2.5 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 KPI36175.1 - 0.0012 17.8 0.2 0.043 12.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KPI36175.1 - 0.006 15.6 0.4 0.014 14.4 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.1 KPI36176.1 - 1.3e-106 356.3 0.0 1.6e-106 356.1 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KPI36176.1 - 5.5e-09 35.9 0.3 1.7e-05 24.6 0.1 3.4 2 2 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KPI36176.1 - 5.3e-08 33.1 3.1 6.2e-06 26.4 1.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI36176.1 - 3e-06 27.2 0.0 0.16 11.8 0.0 3.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.2 KPI36177.1 - 3.7e-89 293.1 24.0 8.3e-19 67.7 0.8 7.1 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KPI36177.1 - 1.1e-73 239.5 19.0 9.9e-07 28.2 0.1 14.9 14 0 0 14 14 14 12 Ankyrin repeat Ank_4 PF13637.1 KPI36177.1 - 2.4e-62 206.2 13.9 1.5e-12 47.6 0.1 9.7 3 2 6 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 KPI36177.1 - 4.1e-56 185.7 17.1 2.8e-08 33.7 0.2 11.2 4 2 8 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI36177.1 - 7.4e-54 174.3 7.5 0.00066 19.6 0.0 14.9 14 0 0 14 14 14 10 Ankyrin repeat NACHT PF05729.7 KPI36177.1 - 2.1e-11 43.7 0.0 4.7e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KPI36177.1 - 4.1e-06 26.9 0.0 1.8e-05 24.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KPI36177.1 - 5.5e-06 26.4 0.8 5.8e-05 23.1 0.0 3.0 3 1 0 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 KPI36177.1 - 0.025 14.3 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase Syntaxin-6_N PF09177.6 KPI36178.1 - 1.9 8.9 11.4 0.49 10.8 1.6 3.0 3 0 0 3 3 3 0 Syntaxin 6, N-terminal OmpH PF03938.9 KPI36178.1 - 3.6 7.5 11.4 2.3 8.1 5.6 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.5 KPI36178.1 - 4 7.5 5.4 0.84 9.7 0.5 2.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF641 PF04859.7 KPI36178.1 - 8.8 6.0 9.1 3.7 7.2 0.8 2.9 2 1 2 4 4 4 0 Plant protein of unknown function (DUF641) MFS_2 PF13347.1 KPI36179.1 - 6e-12 44.6 12.5 6e-12 44.6 8.6 2.1 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 KPI36179.1 - 0.92 9.3 0.0 0.92 9.3 0.0 4.1 5 0 0 5 5 5 0 MFS_1 like family DUF1228 PF06779.9 KPI36179.1 - 1.4 9.0 9.5 3.5 7.7 0.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) GCD14 PF08704.5 KPI36180.1 - 2.5e-06 27.1 0.1 0.0047 16.4 0.0 2.2 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Fungal_trans PF04082.13 KPI36183.1 - 5.8e-08 31.9 0.5 1e-07 31.1 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KPI36184.1 - 4.4e-05 22.3 6.9 4.4e-05 22.3 4.8 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily STT3 PF02516.9 KPI36185.1 - 3.4e-127 425.3 39.2 2.8e-122 409.1 26.3 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit DUF2498 PF10692.4 KPI36185.1 - 0.17 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) Bac_luciferase PF00296.15 KPI36186.1 - 1.6e-58 198.2 0.2 2e-58 197.9 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase CLP_protease PF00574.18 KPI36187.1 - 4.7e-66 221.9 0.0 1.4e-64 217.1 0.0 2.3 1 1 0 1 1 1 1 Clp protease Fungal_trans PF04082.13 KPI36187.1 - 1e-13 50.7 0.0 1.7e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_2 PF07883.6 KPI36188.1 - 0.00055 19.3 0.1 0.0014 18.1 0.0 1.7 2 0 0 2 2 2 1 Cupin domain CKS PF01111.14 KPI36189.1 - 4.9e-33 112.7 0.1 6.2e-33 112.4 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit TMF_TATA_bd PF12325.3 KPI36190.1 - 0.01 15.5 1.9 0.02 14.6 1.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding VWA_2 PF13519.1 KPI36191.1 - 1.9e-07 31.3 0.3 8.3e-06 26.0 0.1 2.4 2 1 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 KPI36191.1 - 0.0038 16.6 1.5 0.0081 15.6 1.1 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif VWA PF00092.23 KPI36191.1 - 0.0099 15.6 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 KPI36191.1 - 0.05 13.2 0.1 0.3 10.6 0.0 2.1 3 0 0 3 3 3 0 Ssl1-like Glyoxalase_2 PF12681.2 KPI36192.1 - 9.5e-06 26.1 0.0 2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase-like domain NAD_binding_1 PF00175.16 KPI36193.1 - 2.9e-08 34.2 0.0 8.9e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KPI36193.1 - 0.00013 21.8 0.0 0.44 10.4 0.1 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KPI36193.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain FAD_binding_6 PF00970.19 KPI36193.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain SKG6 PF08693.5 KPI36194.1 - 0.00045 19.4 0.4 0.00085 18.5 0.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 KPI36194.1 - 0.00089 18.8 0.4 0.0014 18.2 0.3 1.2 1 0 0 1 1 1 1 Podoplanin TPPII_N PF12583.3 KPI36194.1 - 4.7 7.3 9.9 9.3 6.3 6.9 1.4 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Ribosomal_60s PF00428.14 KPI36195.1 - 1.2e-26 92.9 8.4 1.4e-26 92.7 5.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Mito_carr PF00153.22 KPI36196.1 - 1.2e-59 197.9 1.1 4.4e-22 77.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 KPI36196.1 - 0.075 13.0 0.1 0.41 10.7 0.1 2.3 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Peptidase_C2 PF00648.16 KPI36197.1 - 3.2e-17 62.4 0.0 6.4e-16 58.2 0.0 2.2 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.17 KPI36197.1 - 2.7e-15 56.2 0.1 9.9e-13 47.9 0.0 2.6 2 0 0 2 2 2 2 Calpain large subunit, domain III MIT PF04212.13 KPI36197.1 - 0.00044 20.0 0.0 0.00082 19.2 0.0 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain CBFD_NFYB_HMF PF00808.18 KPI36198.1 - 8e-21 73.8 1.1 1.1e-20 73.4 0.8 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KPI36198.1 - 1.7e-05 24.8 0.1 2.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 KPI36198.1 - 0.00064 19.4 0.0 0.00081 19.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 KPI36198.1 - 0.00079 19.1 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 KPI36198.1 - 0.026 14.7 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Sulfotransfer_3 PF13469.1 KPI36199.1 - 0.0076 17.1 0.1 0.013 16.4 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Glyco_transf_22 PF03901.12 KPI36200.1 - 7e-36 124.1 19.5 9e-36 123.7 13.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF1656 PF07869.7 KPI36200.1 - 0.0054 16.4 1.3 0.064 13.0 0.9 3.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1656) MerC PF03203.9 KPI36200.1 - 0.021 15.1 2.5 0.021 15.1 1.7 3.3 3 1 0 3 3 3 0 MerC mercury resistance protein Abhydrolase_3 PF07859.8 KPI36201.1 - 1.1e-06 28.3 1.0 0.00095 18.7 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI36201.1 - 0.00019 21.3 1.2 0.0003 20.7 0.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI36201.1 - 0.00042 20.0 0.0 0.00081 19.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KPI36201.1 - 0.00099 19.3 1.5 0.0019 18.4 0.2 2.0 2 1 0 2 2 2 1 Thioesterase domain FAM181 PF15238.1 KPI36201.1 - 0.024 14.6 2.4 0.037 14.0 1.6 1.3 1 0 0 1 1 1 0 FAM181 DUF3089 PF11288.3 KPI36201.1 - 0.096 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) AA_permease_2 PF13520.1 KPI36202.1 - 6.3e-54 183.1 55.6 7.7e-54 182.8 38.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI36202.1 - 6.6e-27 93.9 48.0 9e-27 93.5 33.3 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.20 KPI36203.1 - 4.3e-15 56.0 0.1 7.4e-15 55.2 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KPI36203.1 - 1.4e-05 24.8 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI36203.1 - 0.0014 18.0 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sybindin PF04099.7 KPI36204.1 - 9.3e-37 125.9 0.0 1.1e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KPI36204.1 - 3.4e-05 23.7 0.0 9.2e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region DUF3645 PF12359.3 KPI36204.1 - 0.053 12.6 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) Abhydrolase_6 PF12697.2 KPI36206.1 - 2.6e-11 43.8 0.0 5.6e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI36206.1 - 3.2e-09 36.6 0.0 4.5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI36206.1 - 0.00018 21.1 0.2 0.0039 16.7 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI36206.1 - 0.0012 18.1 0.1 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Tna_leader PF08053.6 KPI36206.1 - 0.023 14.0 0.1 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 Tryptophanese operon leader peptide Hydrolase_4 PF12146.3 KPI36206.1 - 0.041 13.7 0.1 0.098 12.5 0.0 1.7 2 0 0 2 2 2 0 Putative lysophospholipase BAAT_C PF08840.6 KPI36206.1 - 0.082 12.5 0.0 0.18 11.5 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal EMG1 PF03587.9 KPI36207.1 - 4e-79 264.6 0.0 4.6e-79 264.4 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase HTH_32 PF13565.1 KPI36208.1 - 0.021 15.5 0.0 1.1 10.1 0.0 2.9 2 0 0 2 2 2 0 Homeodomain-like domain Sdh_cyt PF01127.17 KPI36209.1 - 8.4e-10 38.5 1.1 1.3e-09 37.9 0.8 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fungal_trans PF04082.13 KPI36210.1 - 3.9e-12 45.6 0.0 7.2e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amino_oxidase PF01593.19 KPI36211.1 - 3.5e-94 316.4 0.1 2e-93 313.9 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 KPI36211.1 - 1e-10 41.5 0.0 3.1e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 KPI36211.1 - 2.7e-08 33.7 0.0 7.2e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI36211.1 - 1.2e-07 30.9 0.0 1.6e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HMG_box PF00505.14 KPI36211.1 - 2.2e-05 24.6 0.5 0.0087 16.3 0.2 2.6 2 0 0 2 2 2 1 HMG (high mobility group) box NAD_binding_9 PF13454.1 KPI36211.1 - 7.2e-05 22.6 0.1 0.027 14.2 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding HMG_box_2 PF09011.5 KPI36211.1 - 0.0034 17.7 0.2 0.017 15.4 0.1 2.2 1 1 0 1 1 1 1 HMG-box domain Pyr_redox_2 PF07992.9 KPI36211.1 - 0.021 14.6 0.0 0.056 13.3 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI36211.1 - 0.023 14.7 0.1 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI36211.1 - 0.09 13.1 0.0 0.7 10.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_transf_25 PF01755.12 KPI36212.1 - 0.00033 20.3 0.2 0.0029 17.2 0.2 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF3392 PF11872.3 KPI36212.1 - 0.02 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3392) Cgr1 PF03879.9 KPI36213.1 - 2.6e-36 124.1 31.0 3.1e-36 123.8 21.5 1.0 1 0 0 1 1 1 1 Cgr1 family CCDC74_C PF14917.1 KPI36213.1 - 0.0099 15.9 2.2 0.0099 15.9 1.5 1.6 2 0 0 2 2 2 1 Coiled coil protein 74, C terminal CAF-1_p150 PF11600.3 KPI36213.1 - 0.053 12.8 22.1 0.063 12.6 15.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PRP1_N PF06424.7 KPI36213.1 - 0.079 13.2 11.5 0.091 13.0 8.0 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal AIF_C PF14721.1 KPI36213.1 - 4.4 7.5 6.3 7.1 6.8 4.4 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SPT2 PF08243.6 KPI36214.1 - 0.0026 18.0 18.1 0.0026 18.0 12.5 2.4 2 1 0 2 2 2 1 SPT2 chromatin protein PAT1 PF09770.4 KPI36214.1 - 2.2 6.4 14.4 3.6 5.7 10.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Xan_ur_permease PF00860.15 KPI36215.1 - 1.2e-23 83.2 33.0 8.5e-22 77.1 22.9 3.1 1 1 0 1 1 1 1 Permease family MFS_1 PF07690.11 KPI36216.1 - 3.3e-36 124.7 54.3 1.1e-35 122.9 36.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI36216.1 - 2.6e-12 46.0 10.1 2.6e-12 46.0 7.0 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KPI36216.1 - 5.4e-11 41.4 28.0 1.3e-10 40.1 19.4 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1746 PF08508.5 KPI36217.1 - 2.5e-21 75.7 0.7 3.5e-21 75.3 0.5 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RNA_pol_Rpb4 PF03874.11 KPI36218.1 - 2.7e-17 62.8 0.6 3.2e-17 62.5 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 AA_permease_2 PF13520.1 KPI36219.1 - 3.8e-63 213.5 46.3 4.7e-63 213.2 32.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI36219.1 - 2.6e-19 68.9 33.2 3.5e-19 68.5 23.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4181 PF13789.1 KPI36219.1 - 4.7 7.1 15.4 0.028 14.3 2.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) AAA PF00004.24 KPI36220.1 - 1.4e-35 122.3 0.0 2.7e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KPI36220.1 - 0.0045 16.9 0.1 0.029 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KPI36220.1 - 0.019 15.0 0.0 1.9 8.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain Peptidase_C78 PF07910.8 KPI36222.1 - 3.5e-44 150.5 0.0 5.4e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 NHL PF01436.16 KPI36224.1 - 0.097 12.6 0.2 2.6 8.1 0.1 3.2 4 0 0 4 4 4 0 NHL repeat Dioxygenase_C PF00775.16 KPI36225.1 - 6.3e-12 45.1 0.1 1.2e-11 44.2 0.1 1.5 1 1 0 1 1 1 1 Dioxygenase Bromodomain PF00439.20 KPI36226.1 - 2e-35 120.5 1.3 1.3e-16 60.2 0.1 2.5 2 0 0 2 2 2 2 Bromodomain Dus PF01207.12 KPI36227.1 - 8.3e-28 97.1 0.0 1.7e-27 96.0 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) MarR_2 PF12802.2 KPI36228.1 - 0.093 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 MarR family Brix PF04427.13 KPI36229.1 - 3.4e-27 95.3 0.0 4.9e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain Rifin_STEVOR PF02009.11 KPI36230.1 - 0.00032 20.4 0.0 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family SKG6 PF08693.5 KPI36230.1 - 0.0016 17.7 1.8 0.0036 16.5 1.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1183 PF06682.7 KPI36230.1 - 0.036 13.6 0.5 0.083 12.4 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Otopetrin PF03189.8 KPI36230.1 - 0.18 10.7 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Otopetrin Metallophos PF00149.23 KPI36231.1 - 1.3e-09 37.8 0.1 4.6e-09 35.9 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KPI36231.1 - 0.00091 19.0 0.0 0.0026 17.5 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Yos1 PF08571.5 KPI36232.1 - 2.1e-26 91.8 0.1 3e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Yos1-like Dynamitin PF04912.9 KPI36233.1 - 6.2e-20 71.3 4.7 8.7e-10 37.9 0.0 2.4 2 0 0 2 2 2 2 Dynamitin LPP PF04728.8 KPI36233.1 - 0.078 12.7 7.1 0.88 9.4 0.4 4.3 5 0 0 5 5 5 0 Lipoprotein leucine-zipper APG6 PF04111.7 KPI36233.1 - 0.36 9.8 5.4 4.8 6.1 0.1 3.1 3 0 0 3 3 3 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 KPI36233.1 - 0.41 10.3 8.5 1.1 9.0 0.0 3.7 3 2 0 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 KPI36233.1 - 0.62 9.9 5.2 16 5.3 0.4 3.4 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 KPI36233.1 - 1.3 7.3 7.8 4.8 5.5 0.1 2.6 2 1 1 3 3 3 0 AAA domain DUF1192 PF06698.6 KPI36233.1 - 3.3 7.5 12.4 1.2 8.9 0.0 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) DUF4267 PF14087.1 KPI36234.1 - 8.9e-12 44.6 0.1 1.1e-11 44.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DoxX PF07681.7 KPI36234.1 - 0.023 15.0 1.1 0.029 14.7 0.8 1.3 1 0 0 1 1 1 0 DoxX DUF3509 PF12021.3 KPI36235.1 - 0.062 13.0 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) F-box-like_2 PF13013.1 KPI36235.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.7 1 1 0 1 1 1 0 F-box-like domain DUF2414 PF10309.4 KPI36236.1 - 1.2e-17 63.3 0.0 2e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) HET PF06985.6 KPI36237.1 - 6.7e-20 71.6 5.6 1.6e-17 63.9 0.8 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.23 KPI36238.1 - 8.6e-80 268.1 0.1 1.1e-79 267.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI36238.1 - 4.4e-08 33.9 0.0 1.2e-07 32.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aa_trans PF01490.13 KPI36240.1 - 1.1e-22 80.1 39.0 1.2e-22 79.9 27.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NADH_Oxid_Nqo15 PF11497.3 KPI36240.1 - 0.059 13.0 0.1 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 NADH-quinone oxidoreductase chain 15 F-box-like_2 PF13013.1 KPI36241.1 - 0.0012 18.5 0.0 0.0043 16.7 0.0 1.9 2 0 0 2 2 2 1 F-box-like domain F-box-like PF12937.2 KPI36241.1 - 0.0038 16.9 0.0 0.01 15.5 0.0 1.7 1 1 0 1 1 1 1 F-box-like WSC PF01822.14 KPI36243.1 - 6.8e-38 128.4 21.8 1.7e-19 69.5 5.2 2.7 2 0 0 2 2 2 2 WSC domain Pkinase PF00069.20 KPI36244.1 - 3.6e-12 46.0 0.0 5.3e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KPI36244.1 - 0.014 14.4 0.1 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PDZ_assoc PF10600.4 KPI36244.1 - 0.054 13.7 0.4 0.16 12.2 0.3 1.8 1 0 0 1 1 1 0 PDZ-associated domain of NMDA receptors Pkinase_Tyr PF07714.12 KPI36244.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase MFS_1 PF07690.11 KPI36246.1 - 7.2e-31 107.1 42.2 7.2e-31 107.1 29.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KPI36246.1 - 8.7e-12 44.0 11.7 8.7e-12 44.0 8.1 2.1 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KPI36246.1 - 1.4e-05 23.9 20.8 3.7e-05 22.4 7.1 3.1 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 KPI36246.1 - 0.0041 15.3 4.4 0.0072 14.4 3.1 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector DUF2846 PF11008.3 KPI36246.1 - 0.024 14.4 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) OATP PF03137.15 KPI36246.1 - 0.11 10.5 6.0 0.059 11.4 0.3 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KPI36247.1 - 2.9e-20 72.2 34.6 2.9e-20 72.2 24.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily LacY_symp PF01306.14 KPI36247.1 - 4.2 5.8 13.4 0.28 9.6 0.2 2.7 2 1 0 2 2 2 0 LacY proton/sugar symporter Pkinase PF00069.20 KPI36248.1 - 1.5e-44 152.1 0.0 2.2e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI36248.1 - 4.8e-17 61.8 0.0 8e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI36248.1 - 0.00066 18.7 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KPI36248.1 - 0.0013 18.0 0.5 0.0023 17.2 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KPI36248.1 - 0.051 12.6 0.1 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldo_ket_red PF00248.16 KPI36253.1 - 3e-38 131.2 0.0 3.5e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.2 KPI36255.1 - 2.7e-59 197.5 7.4 1.1e-10 41.6 0.0 11.6 7 4 6 13 13 13 9 Ankyrin repeats (3 copies) Ank PF00023.25 KPI36255.1 - 1.3e-32 109.9 35.4 8e-05 22.2 0.0 15.5 17 0 0 17 17 17 7 Ankyrin repeat Ank_4 PF13637.1 KPI36255.1 - 3.2e-32 110.3 27.0 2.2e-10 40.7 0.0 13.8 12 2 3 15 15 15 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KPI36255.1 - 7.8e-29 99.0 19.6 1.2e-05 25.3 0.0 12.3 10 3 2 12 12 12 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI36255.1 - 2.3e-24 83.0 18.1 0.0073 16.4 0.0 14.9 15 0 0 15 15 15 7 Ankyrin repeat NACHT PF05729.7 KPI36255.1 - 3.7e-06 26.6 0.0 1.2e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KPI36255.1 - 8.6e-06 25.8 0.0 3.5e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 KPI36255.1 - 0.0025 17.5 2.6 0.056 13.2 0.0 4.0 4 0 0 4 4 4 1 Part of AAA domain DUF3028 PF11229.3 KPI36255.1 - 0.027 12.7 0.0 0.044 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3028) Sugar_tr PF00083.19 KPI36256.1 - 1.6e-72 244.5 25.8 2e-72 244.2 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI36256.1 - 6.8e-29 100.6 43.3 5.9e-28 97.6 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pam17 PF08566.5 KPI36256.1 - 0.8 9.3 3.3 0.28 10.8 0.2 1.8 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 HET PF06985.6 KPI36258.1 - 4.5e-30 104.6 1.5 7.3e-30 103.9 1.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like_2 PF13013.1 KPI36259.1 - 2.1e-05 24.2 0.2 0.00044 19.9 0.0 2.3 2 1 0 2 2 2 1 F-box-like domain F-box-like PF12937.2 KPI36259.1 - 0.0043 16.7 0.0 0.0082 15.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KPI36259.1 - 0.052 13.2 0.7 0.7 9.6 0.5 2.5 1 1 0 1 1 1 0 F-box domain AMP-binding PF00501.23 KPI36260.1 - 2.1e-16 59.3 0.0 3e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans PF04082.13 KPI36262.1 - 1.4e-25 89.7 2.9 2.7e-25 88.7 0.0 2.5 3 0 0 3 3 3 1 Fungal specific transcription factor domain NmrA PF05368.8 KPI36263.1 - 2.4e-44 151.3 0.0 2.9e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI36263.1 - 1.4e-08 34.9 0.0 1.9e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KPI36263.1 - 9.3e-05 21.5 0.1 0.00072 18.6 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 KPI36263.1 - 0.0014 17.4 0.0 0.002 16.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KPI36263.1 - 0.0017 17.7 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KPI36263.1 - 0.016 15.4 0.2 0.067 13.4 0.0 2.1 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 KPI36263.1 - 0.082 12.9 0.1 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Nitroreductase PF00881.19 KPI36264.1 - 0.027 14.2 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Nitroreductase family Cupin_1 PF00190.17 KPI36265.1 - 7.9e-29 99.9 0.1 9.1e-16 57.5 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KPI36265.1 - 6.7e-27 92.8 3.0 1.5e-14 53.2 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KPI36265.1 - 1.5e-09 37.0 0.3 0.00075 18.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 KPI36265.1 - 1.2e-05 25.0 0.0 0.027 14.0 0.0 2.3 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.14 KPI36265.1 - 2.1e-05 24.2 0.9 0.13 11.9 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cpn10 PF00166.16 KPI36265.1 - 0.056 13.3 0.0 6 6.8 0.0 2.3 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit THDPS_N PF14790.1 KPI36266.1 - 0.12 12.0 0.0 0.42 10.2 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Glyco_transf_90 PF05686.7 KPI36267.1 - 1.1e-16 60.5 1.0 1.5e-08 33.7 0.4 3.4 2 1 0 2 2 2 2 Glycosyl transferase family 90 ECH PF00378.15 KPI36269.1 - 5.2e-54 182.9 0.0 6.4e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KPI36269.1 - 0.00075 19.2 0.1 0.02 14.6 0.0 2.2 1 1 1 2 2 2 1 Peptidase family S49 Ank_2 PF12796.2 KPI36270.1 - 1.3e-23 83.1 0.5 2.7e-09 37.2 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KPI36270.1 - 3.4e-20 70.7 0.6 8e-05 22.2 0.1 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 KPI36270.1 - 5.4e-20 69.4 0.2 1e-05 25.2 0.1 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KPI36270.1 - 8.4e-18 64.3 1.2 7.1e-11 42.3 0.2 3.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KPI36270.1 - 2.1e-12 46.8 2.1 3.2e-07 30.3 0.2 4.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) CorA PF01544.13 KPI36270.1 - 0.004 16.2 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Peptidase_S9 PF00326.16 KPI36271.1 - 2.3e-50 170.7 0.3 3.6e-50 170.1 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KPI36271.1 - 3.9e-07 29.9 0.1 1.9e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.7 KPI36271.1 - 0.0038 16.8 3.8 0.091 12.4 0.1 3.3 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Adeno_hexon PF01065.14 KPI36272.1 - 0.059 12.2 0.2 0.077 11.8 0.1 1.1 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain HTH_32 PF13565.1 KPI36272.1 - 0.21 12.4 0.1 0.21 12.4 0.1 3.2 5 2 1 6 6 6 0 Homeodomain-like domain BTB PF00651.26 KPI36273.1 - 4.9e-16 58.7 0.0 8.5e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain NmrA PF05368.8 KPI36274.1 - 2.2e-31 108.9 0.0 2.7e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI36274.1 - 6.1e-07 29.6 0.1 9.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KPI36274.1 - 2.7e-06 26.3 0.0 3.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KPI36274.1 - 0.0007 19.1 0.1 0.001 18.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KPI36274.1 - 0.0029 17.5 0.4 0.0058 16.5 0.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI36274.1 - 0.0035 17.0 0.5 0.0077 15.9 0.3 1.7 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 KPI36274.1 - 0.083 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein B5 PF03484.10 KPI36274.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase B5 domain WLM PF08325.5 KPI36275.1 - 1.8e-40 138.8 5.1 3.9e-34 118.1 0.1 2.4 1 1 1 2 2 2 2 WLM domain zf-RanBP PF00641.13 KPI36275.1 - 0.00017 20.6 0.6 0.00017 20.6 0.4 2.8 2 1 0 2 2 2 1 Zn-finger in Ran binding protein and others DZR PF12773.2 KPI36275.1 - 0.023 14.4 6.4 0.16 11.7 4.5 2.2 1 1 0 1 1 1 0 Double zinc ribbon PIF1 PF05970.9 KPI36275.1 - 0.066 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase RecR PF02132.10 KPI36275.1 - 0.99 8.8 5.5 0.53 9.7 0.7 2.7 2 1 0 2 2 2 0 RecR protein OrfB_Zn_ribbon PF07282.6 KPI36275.1 - 2.6 7.7 5.6 9.3 5.9 1.6 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF4013 PF13197.1 KPI36276.1 - 0.011 15.0 0.1 0.011 15.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4013) adh_short PF00106.20 KPI36277.1 - 2.3e-12 47.1 0.1 4.3e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI36277.1 - 7.9e-08 32.1 0.1 1.3e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF2202 PF09968.4 KPI36277.1 - 0.044 13.4 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) Aldedh PF00171.17 KPI36278.1 - 2.6e-144 481.0 1.5 6.1e-142 473.2 1.0 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KPI36278.1 - 0.14 11.3 0.0 0.72 9.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) CBAH PF02275.13 KPI36279.1 - 1.8e-33 116.3 0.1 6.2e-32 111.2 0.1 2.1 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family Pro_isomerase PF00160.16 KPI36280.1 - 6.5e-38 130.3 0.6 7.8e-38 130.1 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD His_Phos_1 PF00300.17 KPI36281.1 - 2.9e-13 50.1 0.0 5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1352 PF07086.7 KPI36282.1 - 0.12 11.9 2.7 5.8 6.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1352) ATP1G1_PLM_MAT8 PF02038.11 KPI36282.1 - 0.23 10.5 1.3 0.61 9.1 0.2 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DUF1776 PF08643.5 KPI36283.1 - 4.4e-64 216.4 0.0 5.6e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.1 KPI36284.1 - 2.6e-27 96.1 0.0 2.8e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI36284.1 - 2.9e-17 63.0 0.0 3.9e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI36284.1 - 5.6e-08 32.6 0.0 8.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF3752 PF12572.3 KPI36285.1 - 1.6e-35 122.4 12.9 1.6e-35 122.4 8.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) DUF605 PF04652.11 KPI36286.1 - 1.1e-87 294.9 39.9 9.8e-86 288.5 27.7 2.1 1 1 0 1 1 1 1 Vta1 like adh_short_C2 PF13561.1 KPI36287.1 - 7.5e-23 81.5 0.5 8.4e-14 51.9 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI36287.1 - 3.9e-16 59.3 5.2 7.5e-12 45.4 0.8 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 KPI36287.1 - 3.7e-07 29.9 1.9 3.4e-06 26.8 0.1 2.1 1 1 1 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.14 KPI36287.1 - 0.017 14.2 0.2 0.041 13.0 0.1 1.6 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KPI36287.1 - 0.037 13.7 0.2 0.059 13.0 0.2 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Epimerase PF01370.16 KPI36287.1 - 0.038 13.4 0.1 0.072 12.5 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ProRS-C_1 PF09180.6 KPI36287.1 - 0.061 13.2 0.6 4.3 7.3 0.0 2.7 2 1 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal F420_oxidored PF03807.12 KPI36287.1 - 0.078 13.4 0.8 0.14 12.5 0.6 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pro_racemase PF05544.6 KPI36288.1 - 6.9e-82 274.8 0.0 7.8e-82 274.7 0.0 1.0 1 0 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.11 KPI36288.1 - 0.00045 19.5 0.1 0.00074 18.8 0.0 1.5 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein QueC PF06508.8 KPI36288.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Sugar_tr PF00083.19 KPI36291.1 - 3.2e-93 312.7 30.0 3.7e-93 312.5 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI36291.1 - 1.4e-11 43.7 31.4 1.4e-11 43.7 21.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SurA_N_2 PF13623.1 KPI36291.1 - 0.039 13.9 0.1 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 SurA N-terminal domain DUF1228 PF06779.9 KPI36291.1 - 0.041 13.8 7.9 0.26 11.3 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) RRM_1 PF00076.17 KPI36293.1 - 2.1e-34 116.9 0.1 5.7e-18 64.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRI12 PF06609.8 KPI36293.1 - 5.2e-29 100.8 25.0 7.7e-29 100.3 17.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RRM_6 PF14259.1 KPI36293.1 - 5.7e-26 90.2 0.1 4e-14 52.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 KPI36293.1 - 1.1e-21 77.0 52.0 1.1e-20 73.7 33.4 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily RRM_5 PF13893.1 KPI36293.1 - 1.3e-14 53.8 0.0 4.9e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 KPI36293.1 - 1.5e-08 33.6 11.2 1.5e-08 33.6 7.7 3.7 4 0 0 4 4 4 1 Sugar (and other) transporter Bac_luciferase PF00296.15 KPI36294.1 - 0.014 14.4 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Luciferase-like monooxygenase Sugar_tr PF00083.19 KPI36299.1 - 3.7e-75 253.2 17.6 4.2e-75 253.0 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI36299.1 - 1.2e-25 90.0 17.5 1.2e-25 90.0 12.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF986 PF06173.7 KPI36299.1 - 0.11 12.2 0.2 0.25 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF986) GNAT_acetyltr_2 PF13718.1 KPI36300.1 - 1.1e-80 269.5 0.0 2.2e-80 268.5 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KPI36300.1 - 6.4e-66 221.3 0.0 3e-65 219.1 0.0 2.2 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 KPI36300.1 - 4.1e-40 135.3 0.0 9.9e-40 134.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KPI36300.1 - 1.5e-31 108.4 1.9 4.8e-31 106.8 1.3 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 KPI36300.1 - 0.0072 16.4 0.0 0.022 14.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AA_permease PF00324.16 KPI36301.1 - 4.1e-133 444.2 39.9 4.6e-133 444.0 27.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI36301.1 - 5.7e-39 133.8 45.1 7.3e-39 133.4 31.3 1.1 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.19 KPI36302.1 - 1.3e-62 211.8 18.7 2.2e-61 207.8 13.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI36302.1 - 1.9e-10 40.0 31.0 9.2e-08 31.1 4.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Aldo_ket_red PF00248.16 KPI36303.1 - 1.2e-62 211.2 0.0 2.4e-62 210.3 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family DUF3950 PF13132.1 KPI36303.1 - 0.3 10.6 0.2 0.3 10.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) Aldedh PF00171.17 KPI36304.1 - 3.6e-177 589.3 0.0 4.1e-177 589.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PAS_9 PF13426.1 KPI36306.1 - 9.9e-15 54.7 0.0 2.5e-11 43.8 0.0 2.7 2 0 0 2 2 2 2 PAS domain DUF1479 PF07350.7 KPI36308.1 - 0.00037 19.1 0.0 0.037 12.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.8 KPI36308.1 - 0.04 13.9 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) ADH_zinc_N PF00107.21 KPI36309.1 - 3.2e-06 26.7 0.0 5.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KPI36309.1 - 0.078 12.6 0.1 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated F-box-like_2 PF13013.1 KPI36313.1 - 0.0038 16.9 0.1 0.0084 15.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like domain F-box-like_2 PF13013.1 KPI36314.1 - 0.034 13.8 0.1 0.063 12.9 0.1 1.6 1 1 0 1 1 1 0 F-box-like domain F-box-like_2 PF13013.1 KPI36316.1 - 0.0058 16.3 0.0 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 F-box-like domain SNase PF00565.12 KPI36317.1 - 1.5e-21 76.6 0.5 4.1e-21 75.2 0.1 1.8 2 0 0 2 2 2 1 Staphylococcal nuclease homologue GFA PF04828.9 KPI36318.1 - 0.00024 20.9 3.0 0.00024 20.9 2.1 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF4440 PF14534.1 KPI36319.1 - 0.00026 21.1 0.0 0.33 11.1 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4440) DUF4267 PF14087.1 KPI36320.1 - 1.3e-17 63.4 0.8 3.2e-17 62.1 0.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4267) Vma12 PF11712.3 KPI36320.1 - 0.15 11.8 0.2 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Glyco_hydro_76 PF03663.9 KPI36321.1 - 6.5e-127 423.9 23.5 8.4e-127 423.5 16.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KPI36321.1 - 0.0036 16.3 3.4 0.0036 16.3 2.4 1.9 1 1 1 2 2 2 1 Glycosyl Hydrolase Family 88 GST_C PF00043.20 KPI36323.1 - 1.7e-05 24.7 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI36323.1 - 0.00034 20.4 0.1 0.0011 18.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KPI36323.1 - 0.03 14.5 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain AP_endonuc_2 PF01261.19 KPI36324.1 - 1.4e-26 93.0 0.7 1.8e-26 92.7 0.5 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.7 KPI36324.1 - 2.1e-12 46.4 0.2 3.6e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 AP endonuclease family 2 C terminus Transferase PF02458.10 KPI36325.1 - 2.9e-08 32.5 0.0 4.2e-06 25.4 0.0 2.8 1 1 1 2 2 2 2 Transferase family DUF1313 PF07011.6 KPI36325.1 - 0.075 12.7 0.1 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1313) p450 PF00067.17 KPI36326.1 - 2.3e-55 187.9 0.0 3.4e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 KPI36326.1 - 4.7e-26 92.0 0.0 1.5e-25 90.4 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI36326.1 - 1.3e-17 64.1 0.0 3e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI36326.1 - 1.5e-07 31.3 0.0 1.3e-06 28.2 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KPI36326.1 - 0.0014 18.1 0.0 0.0029 17.0 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Transferase PF02458.10 KPI36327.1 - 8.1e-21 73.9 0.1 2.3e-19 69.1 0.1 2.3 2 1 0 2 2 2 1 Transferase family Abhydrolase_6 PF12697.2 KPI36328.1 - 5.2e-13 49.4 8.0 1.1e-12 48.2 5.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KPI36328.1 - 0.14 11.7 0.0 0.41 10.1 0.0 1.9 1 1 0 1 1 1 0 PGAP1-like protein F-box-like_2 PF13013.1 KPI36332.1 - 0.0076 15.9 0.0 0.021 14.5 0.0 1.8 2 0 0 2 2 2 1 F-box-like domain zf-RAG1 PF10426.4 KPI36332.1 - 0.11 12.5 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain zf-RING_2 PF13639.1 KPI36333.1 - 1.3e-13 50.4 6.7 2e-13 49.9 4.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KPI36333.1 - 9.9e-08 31.9 3.0 1.9e-07 31.0 2.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KPI36333.1 - 2e-07 30.5 3.6 3.2e-07 29.8 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI36333.1 - 1.8e-05 24.3 3.7 2.8e-05 23.7 2.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KPI36333.1 - 3.9e-05 23.5 5.4 6.3e-05 22.9 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KPI36333.1 - 8.4e-05 22.1 2.4 0.00013 21.5 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KPI36333.1 - 0.0015 18.3 3.2 0.0035 17.1 2.2 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KPI36333.1 - 0.03 13.8 6.0 0.05 13.1 4.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 KPI36333.1 - 0.16 11.6 5.6 0.29 10.8 3.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 KPI36333.1 - 0.26 11.2 4.9 0.52 10.2 3.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 KPI36333.1 - 0.56 10.2 5.4 1.1 9.3 3.8 1.5 1 0 0 1 1 1 0 RING-variant domain OAD_gamma PF04277.8 KPI36333.1 - 1 9.7 2.3 3.1 8.2 0.0 2.7 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Prok-RING_1 PF14446.1 KPI36333.1 - 2.1 8.1 7.6 0.18 11.5 0.8 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Dicty_REP PF05086.7 KPI36333.1 - 2.2 5.9 5.3 3 5.4 3.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF218 PF02698.12 KPI36334.1 - 1.3e-11 44.2 0.0 3.4e-11 42.8 0.0 1.7 1 1 0 1 1 1 1 DUF218 domain AA_permease_2 PF13520.1 KPI36336.1 - 5.1e-28 97.7 47.9 4e-26 91.5 21.5 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 KPI36336.1 - 1.2e-22 79.9 26.9 1.2e-22 79.9 18.6 2.0 1 1 1 2 2 2 1 Amino acid permease Solute_trans_a PF03619.11 KPI36337.1 - 6.5e-38 130.6 8.0 7.6e-38 130.3 5.5 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF3261 PF11659.3 KPI36338.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3261) Fungal_trans_2 PF11951.3 KPI36339.1 - 5e-50 170.2 1.1 6.9e-50 169.7 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Solute_trans_a PF03619.11 KPI36341.1 - 3.3e-30 105.3 14.1 1.8e-29 102.9 9.7 1.8 1 1 0 1 1 1 1 Organic solute transporter Ostalpha DUF373 PF04123.8 KPI36341.1 - 2.9 6.8 11.3 0.58 9.1 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) SUR7 PF06687.7 KPI36341.1 - 3.1 7.2 11.1 0.11 12.0 1.3 2.5 2 1 0 2 2 2 0 SUR7/PalI family F-box-like_2 PF13013.1 KPI36342.1 - 0.016 14.9 0.8 0.04 13.6 0.0 2.0 2 1 0 2 2 2 0 F-box-like domain F-box-like PF12937.2 KPI36342.1 - 0.066 12.9 0.2 0.2 11.4 0.1 1.9 1 0 0 1 1 1 0 F-box-like gp37_C PF12604.3 KPI36343.1 - 0.0065 16.2 0.1 0.0077 16.0 0.1 1.2 1 0 0 1 1 1 1 Tail fiber protein gp37 C terminal Ribosomal_L4 PF00573.17 KPI36343.1 - 0.039 13.3 1.7 0.057 12.8 1.2 1.3 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family DUF1822 PF08852.6 KPI36343.1 - 0.3 9.8 2.4 0.35 9.6 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) VWA PF00092.23 KPI36344.1 - 3.8e-06 26.7 0.0 2.5e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 KPI36344.1 - 0.00038 20.6 0.0 0.0012 18.9 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain ELO PF01151.13 KPI36346.1 - 3.2e-56 190.4 18.0 3.8e-56 190.1 12.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family p53-inducible11 PF14936.1 KPI36346.1 - 0.074 12.9 0.1 0.95 9.3 0.0 2.3 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 GST_N_2 PF13409.1 KPI36348.1 - 9.9e-26 89.5 0.1 9.8e-25 86.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KPI36348.1 - 3.3e-10 39.7 0.0 9.5e-10 38.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KPI36348.1 - 3.6e-07 30.3 0.1 0.046 13.9 0.0 3.3 2 1 1 3 3 3 2 Glutathione S-transferase, N-terminal domain adh_short PF00106.20 KPI36349.1 - 8.4e-29 100.6 2.8 1.5e-28 99.7 1.9 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI36349.1 - 1.4e-21 77.3 0.4 1.7e-21 77.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI36349.1 - 8.4e-12 45.1 4.9 5.1e-11 42.5 3.4 2.0 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KPI36349.1 - 0.0012 17.8 0.1 0.0015 17.4 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Integrase_Zn PF02022.14 KPI36349.1 - 0.0048 16.3 0.0 0.0097 15.3 0.0 1.4 1 0 0 1 1 1 1 Integrase Zinc binding domain Ldh_1_N PF00056.18 KPI36349.1 - 0.024 14.4 0.3 0.048 13.4 0.2 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 KPI36349.1 - 0.027 14.2 1.5 0.11 12.2 1.0 2.1 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PEX11 PF05648.9 KPI36350.1 - 2.1e-22 79.5 0.1 2.4e-22 79.3 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Cnd1_N PF12922.2 KPI36350.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term adh_short PF00106.20 KPI36351.1 - 1.1e-08 35.2 0.0 1.6e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase PC4 PF02229.11 KPI36352.1 - 1.5e-21 75.4 1.3 3.2e-20 71.1 0.2 2.5 3 0 0 3 3 3 2 Transcriptional Coactivator p15 (PC4) DUF336 PF03928.9 KPI36353.1 - 2.4e-17 62.9 0.3 3e-17 62.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Iron_permease PF04120.7 KPI36354.1 - 3.1e-27 94.7 11.5 8.9e-13 47.9 0.1 4.2 4 0 0 4 4 4 4 Low affinity iron permease DUF4658 PF15555.1 KPI36354.1 - 0.89 9.4 6.5 1.1 9.1 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4658) DUF952 PF06108.7 KPI36355.1 - 8.6e-17 60.7 0.0 1e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) DUF3049 PF11250.3 KPI36355.1 - 0.091 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3049) Pyr_redox_3 PF13738.1 KPI36356.1 - 3.2e-43 148.1 0.0 4.8e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI36356.1 - 0.0025 17.7 0.5 0.017 15.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KPI36356.1 - 0.0067 16.2 0.0 0.11 12.3 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KPI36356.1 - 0.027 14.5 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KPI36356.1 - 0.034 13.9 0.0 2.3 8.0 0.0 2.9 3 0 0 3 3 3 0 ThiF family DAO PF01266.19 KPI36356.1 - 0.049 12.5 0.4 0.16 10.7 0.0 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.12 KPI36356.1 - 0.15 11.1 0.1 0.92 8.5 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Ribosomal_L20 PF00453.13 KPI36357.1 - 0.028 14.3 0.1 0.028 14.3 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L20 Fungal_trans PF04082.13 KPI36359.1 - 4.1e-25 88.1 0.8 6.2e-25 87.5 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_2 PF07992.9 KPI36360.1 - 7.3e-27 94.5 0.5 3.2e-16 59.8 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI36360.1 - 7.7e-12 45.4 0.6 1.2e-08 35.1 0.4 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI36360.1 - 0.00076 19.6 0.6 0.13 12.3 0.0 3.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI36360.1 - 0.0087 14.9 0.4 2.9 6.6 0.0 3.1 3 0 0 3 3 3 2 FAD binding domain NAD_binding_7 PF13241.1 KPI36360.1 - 0.025 14.8 0.0 0.91 9.8 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KPI36360.1 - 0.034 14.1 0.0 7.5 6.6 0.0 3.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KPI36360.1 - 0.047 12.1 0.4 15 3.9 0.0 3.3 4 0 0 4 4 4 0 HI0933-like protein TrkA_N PF02254.13 KPI36360.1 - 0.11 12.4 0.4 22 5.0 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain DAO PF01266.19 KPI36360.1 - 0.51 9.1 2.5 16 4.2 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 KPI36360.1 - 0.51 9.1 2.3 7.5 5.2 0.8 2.3 2 1 0 2 2 2 0 Glucose inhibited division protein A adh_short_C2 PF13561.1 KPI36362.1 - 3.6e-29 102.2 0.7 4.4e-29 101.9 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI36362.1 - 8.1e-26 90.9 0.9 1.2e-25 90.3 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI36362.1 - 1.2e-11 44.5 0.4 2e-11 43.8 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI36362.1 - 0.087 12.2 0.2 0.37 10.2 0.2 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KPI36362.1 - 0.1 12.3 0.2 0.3 10.9 0.2 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2924 PF11149.3 KPI36362.1 - 0.11 12.5 0.0 8.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) AstE_AspA PF04952.9 KPI36364.1 - 7.5e-25 87.3 0.0 1.2e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF1706 PF08020.6 KPI36364.1 - 0.19 11.1 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) FMO-like PF00743.14 KPI36365.1 - 2.9e-23 81.8 0.8 6.3e-23 80.7 0.1 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KPI36365.1 - 1.3e-16 61.3 0.0 5.4e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI36365.1 - 3.2e-09 36.1 0.0 5.4e-06 25.5 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KPI36365.1 - 1.4e-07 31.4 0.0 3e-06 27.1 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KPI36365.1 - 0.0001 22.1 0.1 0.44 10.3 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KPI36365.1 - 0.00055 19.8 0.0 0.039 13.8 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PS_pyruv_trans PF04230.8 KPI36365.1 - 0.027 14.1 0.1 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide pyruvyl transferase CutA1 PF03091.10 KPI36365.1 - 0.086 12.5 0.3 0.19 11.4 0.2 1.5 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Pyr_redox PF00070.22 KPI36365.1 - 0.093 13.1 0.0 38 4.7 0.0 3.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI36365.1 - 0.17 10.9 0.0 8 5.4 0.0 2.3 2 0 0 2 2 2 0 Thi4 family DUF904 PF06005.7 KPI36367.1 - 0.00013 22.1 14.6 0.0024 18.1 3.9 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF904) BLOC1_2 PF10046.4 KPI36367.1 - 0.00069 19.7 9.6 0.028 14.5 1.6 3.2 2 1 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 KPI36367.1 - 0.0018 17.9 10.2 0.003 17.1 7.1 1.3 1 0 0 1 1 1 1 IncA protein CALCOCO1 PF07888.6 KPI36367.1 - 0.003 15.9 4.7 0.0062 14.8 3.2 1.5 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF972 PF06156.8 KPI36367.1 - 0.0035 17.6 7.6 0.029 14.7 1.9 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF972) bZIP_1 PF00170.16 KPI36367.1 - 0.0047 16.8 20.3 0.011 15.6 2.0 3.6 3 1 1 4 4 3 3 bZIP transcription factor Dynamitin PF04912.9 KPI36367.1 - 0.0054 15.5 3.3 0.0075 15.1 2.3 1.2 1 0 0 1 1 1 1 Dynamitin DivIC PF04977.10 KPI36367.1 - 0.0064 15.9 17.4 0.43 10.1 1.6 3.3 1 1 2 3 3 3 2 Septum formation initiator PspA_IM30 PF04012.7 KPI36367.1 - 0.025 13.9 9.7 0.57 9.5 6.7 2.1 1 1 0 1 1 1 0 PspA/IM30 family Spc7 PF08317.6 KPI36367.1 - 0.026 13.1 7.5 0.035 12.7 5.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ERM PF00769.14 KPI36367.1 - 0.027 14.0 13.0 0.067 12.7 9.0 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family SseC PF04888.7 KPI36367.1 - 0.027 13.8 0.4 0.036 13.4 0.3 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family ADIP PF11559.3 KPI36367.1 - 0.029 14.2 8.6 0.06 13.2 5.9 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding MIS13 PF08202.6 KPI36367.1 - 0.034 13.2 9.5 1.7 7.6 6.5 2.8 1 1 0 1 1 1 0 Mis12-Mtw1 protein family DUF3450 PF11932.3 KPI36367.1 - 0.034 13.4 3.4 0.052 12.8 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.3 KPI36367.1 - 0.041 13.6 19.1 0.16 11.8 3.2 3.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Myosin_tail_1 PF01576.14 KPI36367.1 - 0.043 11.5 14.6 0.072 10.8 10.2 1.3 1 0 0 1 1 1 0 Myosin tail Spc24 PF08286.6 KPI36367.1 - 0.063 12.9 7.9 0.99 9.1 1.5 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Dor1 PF04124.7 KPI36367.1 - 0.095 11.1 2.1 0.14 10.6 1.1 1.5 1 1 0 1 1 1 0 Dor1-like family Tektin PF03148.9 KPI36367.1 - 0.11 11.0 7.6 0.039 12.5 0.8 2.5 2 1 1 3 3 3 0 Tektin family CASP_C PF08172.7 KPI36367.1 - 0.14 11.2 5.5 1.3 7.9 3.8 2.2 1 1 0 1 1 1 0 CASP C terminal TMF_TATA_bd PF12325.3 KPI36367.1 - 0.14 11.8 9.4 0.31 10.7 6.5 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.6 KPI36367.1 - 0.15 12.0 6.1 2.2 8.2 0.3 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF334 PF03904.8 KPI36367.1 - 0.17 11.2 3.6 0.2 10.9 1.9 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF334) VIT1 PF01988.14 KPI36367.1 - 0.17 11.3 3.1 0.28 10.6 2.2 1.2 1 0 0 1 1 1 0 VIT family FUSC PF04632.7 KPI36367.1 - 0.18 10.1 0.1 0.22 9.8 0.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family bZIP_2 PF07716.10 KPI36367.1 - 0.19 11.5 18.4 2 8.2 1.6 4.0 2 1 2 4 4 4 0 Basic region leucine zipper GAS PF13851.1 KPI36367.1 - 0.26 10.4 11.8 0.65 9.1 8.2 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 KPI36367.1 - 0.4 10.7 2.3 0.8 9.8 1.6 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.4 KPI36367.1 - 0.44 10.3 13.4 0.79 9.5 5.9 2.7 1 1 1 2 2 2 0 Axonemal dynein light chain ATG16 PF08614.6 KPI36367.1 - 0.45 10.3 12.0 0.22 11.3 4.5 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 KPI36367.1 - 0.45 10.3 16.0 1.5 8.6 4.0 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.9 KPI36367.1 - 0.47 10.0 9.3 1.2 8.7 6.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.7 KPI36367.1 - 0.49 10.1 11.8 0.45 10.2 3.2 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 KPI36367.1 - 0.5 8.1 3.4 0.77 7.5 2.4 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nup54 PF13874.1 KPI36367.1 - 0.57 9.8 4.9 0.48 10.0 0.8 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 OmpH PF03938.9 KPI36367.1 - 1 9.2 5.5 1.8 8.4 3.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MerR-DNA-bind PF09278.6 KPI36367.1 - 1 9.8 5.4 2.5 8.5 0.5 2.8 1 1 1 2 2 2 0 MerR, DNA binding ACCA PF03255.9 KPI36367.1 - 1.1 8.8 4.6 3.2 7.3 0.8 2.3 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Leu_zip PF15294.1 KPI36367.1 - 1.1 8.2 13.1 0.21 10.6 6.4 1.8 2 0 0 2 2 2 0 Leucine zipper Mnd1 PF03962.10 KPI36367.1 - 1.2 8.8 9.5 6.6 6.3 6.6 2.0 1 1 0 1 1 1 0 Mnd1 family Tropomyosin_1 PF12718.2 KPI36367.1 - 1.2 8.9 16.3 7.8 6.3 11.3 2.1 1 1 0 1 1 1 0 Tropomyosin like APG6 PF04111.7 KPI36367.1 - 1.3 7.9 10.7 3.8 6.4 7.4 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF4200 PF13863.1 KPI36367.1 - 1.7 8.5 13.0 1.7 8.5 2.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Herpes_UL6 PF01763.11 KPI36367.1 - 2.3 6.2 5.0 1.8 6.6 2.2 1.7 2 1 0 2 2 2 0 Herpesvirus UL6 like DUF4337 PF14235.1 KPI36367.1 - 2.3 8.0 8.7 2 8.2 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF1192 PF06698.6 KPI36367.1 - 2.5 7.9 11.4 9.4 6.1 1.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) TMCO5 PF14992.1 KPI36367.1 - 2.6 7.1 11.0 7.4 5.6 7.6 1.7 1 1 0 1 1 1 0 TMCO5 family Seryl_tRNA_N PF02403.17 KPI36367.1 - 3.3 7.7 13.2 1.9 8.5 3.6 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TSC22 PF01166.13 KPI36367.1 - 3.6 7.6 14.5 0.18 11.8 1.6 3.6 3 1 1 4 4 3 0 TSC-22/dip/bun family Atg14 PF10186.4 KPI36367.1 - 4.2 6.2 10.8 9 5.1 7.5 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 KPI36367.1 - 4.9 7.6 8.5 7.6 7.0 0.9 2.8 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DivIVA PF05103.8 KPI36367.1 - 5.4 7.0 13.7 87 3.1 0.5 3.0 1 1 1 2 2 2 0 DivIVA protein Striatin PF08232.7 KPI36367.1 - 5.9 7.1 13.5 4 7.7 2.1 3.0 2 1 2 4 4 3 0 Striatin family ORF6C PF10552.4 KPI36367.1 - 6.9 6.4 7.6 7.2 6.3 1.4 2.8 1 1 1 2 2 2 0 ORF6C domain E1-E2_ATPase PF00122.15 KPI36369.1 - 3.6e-61 206.1 8.8 3.6e-61 206.1 6.1 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KPI36369.1 - 1.1e-32 113.0 0.5 1.1e-32 113.0 0.4 2.5 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KPI36369.1 - 2.5e-31 109.7 0.2 5e-29 102.2 0.1 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KPI36369.1 - 2.2e-16 59.0 0.0 5.4e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KPI36369.1 - 1.6e-14 53.6 0.0 3.4e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KPI36369.1 - 2.9e-14 53.6 0.0 5.7e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KPI36369.1 - 3e-08 33.5 0.9 2.9e-06 27.0 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ADH_N PF08240.7 KPI36370.1 - 4.8e-25 87.4 3.5 4.8e-25 87.4 2.4 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI36370.1 - 3.3e-06 26.6 0.1 0.0065 16.0 0.0 2.7 3 0 0 3 3 3 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KPI36370.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Asp PF00026.18 KPI36371.1 - 1.4e-05 24.5 0.0 4.3e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic aspartyl protease 4HBT PF03061.17 KPI36372.1 - 2.2e-10 40.5 0.0 5e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily His_Phos_2 PF00328.17 KPI36373.1 - 8.3e-15 54.9 0.0 3.4e-12 46.3 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Ecm33 PF12454.3 KPI36373.1 - 4.5 7.2 7.0 0.28 11.0 0.2 2.5 3 0 0 3 3 3 0 GPI-anchored cell wall organization protein Rad60-SLD PF11976.3 KPI36374.1 - 1.1e-20 73.0 0.4 1.3e-20 72.8 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KPI36374.1 - 1.1e-08 34.3 0.1 1.3e-08 34.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family 5-nucleotidase PF06189.7 KPI36374.1 - 0.15 10.8 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 5'-nucleotidase DUF427 PF04248.7 KPI36376.1 - 4.2e-34 116.0 0.0 4.5e-27 93.5 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF427) LRR_7 PF13504.1 KPI36377.1 - 0.12 12.6 1.2 2.2 8.8 0.2 3.4 3 0 0 3 3 3 0 Leucine rich repeat DUF1772 PF08592.6 KPI36378.1 - 0.0017 18.1 3.5 0.0092 15.7 2.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) PAS_9 PF13426.1 KPI36379.1 - 8.7e-20 71.0 0.0 1e-17 64.4 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 KPI36379.1 - 0.00023 20.9 0.0 0.00072 19.3 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 KPI36379.1 - 0.0019 18.2 0.0 0.0076 16.2 0.0 2.1 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 KPI36379.1 - 0.13 12.3 0.0 0.52 10.4 0.0 2.0 2 0 0 2 2 2 0 PAS fold Chitin_bind_3 PF03067.10 KPI36380.1 - 7.5e-05 23.0 0.0 9.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Chitin binding domain HET PF06985.6 KPI36381.1 - 3e-30 105.1 0.0 5e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HIT PF01230.18 KPI36383.1 - 4.5e-19 68.8 0.1 8.3e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KPI36383.1 - 0.00041 20.5 0.0 0.00079 19.6 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CHCH PF06747.8 KPI36384.1 - 6e-07 29.2 8.8 8.7e-06 25.5 0.8 2.6 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 KPI36384.1 - 0.0041 16.8 8.9 0.22 11.3 0.5 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 KPI36384.1 - 0.18 11.8 8.5 5.3 7.1 5.3 2.8 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DUF2236 PF09995.4 KPI36385.1 - 4.4e-07 29.4 0.0 0.0016 17.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2236) ABC_tran PF00005.22 KPI36386.1 - 0.015 15.6 0.0 0.078 13.2 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 KPI36386.1 - 0.021 14.3 0.1 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glycogen_syn PF05693.8 KPI36387.1 - 2.2e-261 868.6 0.2 5.1e-217 722.1 0.0 2.0 1 1 1 2 2 2 2 Glycogen synthase Glyco_trans_4_4 PF13579.1 KPI36387.1 - 3.6e-05 23.9 0.1 7.1e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 KPI36387.1 - 9.5e-05 21.9 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain DUF4344 PF14247.1 KPI36388.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4344) GMC_oxred_N PF00732.14 KPI36389.1 - 1.2e-56 192.0 0.0 1.6e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI36389.1 - 1.3e-36 125.9 0.0 4.3e-36 124.3 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KPI36389.1 - 2.2e-05 24.3 0.0 4.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI36389.1 - 0.0017 17.2 0.9 0.0094 14.8 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KPI36389.1 - 0.0032 16.4 0.5 0.018 13.9 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KPI36389.1 - 0.054 12.4 0.3 0.11 11.3 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Tom5 PF10642.4 KPI36390.1 - 2.4e-12 46.2 0.0 2.5e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase F-box-like PF12937.2 KPI36391.1 - 0.00038 20.1 0.3 0.0011 18.6 0.2 1.9 1 0 0 1 1 1 1 F-box-like dCMP_cyt_deam_1 PF00383.17 KPI36392.1 - 1.4e-09 37.5 0.1 1.9e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region WD40 PF00400.27 KPI36393.1 - 3.5e-53 175.6 12.3 9e-10 38.0 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KPI36393.1 - 1.5e-31 109.4 1.0 2.2e-31 108.8 0.7 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 KPI36393.1 - 4.5e-06 26.2 0.0 8.3e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 KPI36393.1 - 2.6e-05 24.0 0.0 0.0011 18.6 0.0 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KPI36393.1 - 0.00021 20.1 0.0 2.9 6.5 0.0 3.5 2 1 2 4 4 4 3 Nup133 N terminal like Nup160 PF11715.3 KPI36393.1 - 0.0048 15.0 0.3 0.068 11.2 0.0 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 polyprenyl_synt PF00348.12 KPI36394.1 - 5.3e-67 225.3 0.0 6.3e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase ILVD_EDD PF00920.16 KPI36395.1 - 9.9e-185 614.8 9.3 1.2e-181 604.7 6.4 2.0 1 1 0 1 1 1 1 Dehydratase family 4HBT_2 PF13279.1 KPI36396.1 - 5.5e-08 33.2 0.0 9.8e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily WW PF00397.21 KPI36397.1 - 6.2e-06 25.9 3.3 1.4e-05 24.8 2.3 1.6 1 0 0 1 1 1 1 WW domain DUF1799 PF08809.6 KPI36397.1 - 0.17 11.6 0.6 0.35 10.6 0.2 1.6 2 0 0 2 2 2 0 Phage related hypothetical protein (DUF1799) Ligase_CoA PF00549.14 KPI36399.1 - 8.8e-32 109.8 0.4 5.2e-16 58.6 0.1 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 KPI36399.1 - 2.1e-11 44.1 2.3 2.2e-11 44.0 0.1 2.3 2 0 0 2 2 2 1 CoA binding domain E1-E2_ATPase PF00122.15 KPI36400.1 - 0.11 11.5 0.6 0.2 10.6 0.4 1.4 1 0 0 1 1 1 0 E1-E2 ATPase MmgE_PrpD PF03972.9 KPI36401.1 - 7e-60 202.4 0.1 9.8e-40 136.0 0.7 2.0 1 1 1 2 2 2 2 MmgE/PrpD family NDK PF00334.14 KPI36402.1 - 8.3e-55 184.2 0.0 9.4e-55 184.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Ank_5 PF13857.1 KPI36403.1 - 4.5e-09 36.2 0.5 3.6e-08 33.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KPI36403.1 - 7e-07 29.6 0.2 2.8e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KPI36403.1 - 5e-05 23.5 0.6 0.0002 21.5 0.3 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KPI36403.1 - 5.1e-05 22.8 2.4 0.0016 18.1 0.2 2.8 2 1 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 KPI36403.1 - 0.0013 18.8 1.0 0.0053 16.8 0.2 2.4 3 0 0 3 3 3 1 Ankyrin repeat Baseplate_J PF04865.9 KPI36403.1 - 0.033 13.5 0.3 0.58 9.4 0.0 2.2 1 1 1 2 2 2 0 Baseplate J-like protein Metallophos_2 PF12850.2 KPI36404.1 - 2.6e-16 59.8 0.0 3.2e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain BTB PF00651.26 KPI36405.1 - 2.4e-11 43.6 0.1 5.5e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ribosomal_L4 PF00573.17 KPI36406.1 - 8.3e-41 139.4 0.7 1.1e-40 139.0 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KPI36406.1 - 1e-28 98.9 0.9 1e-28 98.9 0.7 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Glyco_transf_21 PF13506.1 KPI36407.1 - 9.4e-15 54.3 0.0 4.9e-07 29.1 0.0 2.6 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 KPI36407.1 - 9.5e-10 38.6 0.0 3.5e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KPI36407.1 - 0.00028 20.6 0.0 0.81 9.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 zf-C2H2_4 PF13894.1 KPI36408.1 - 4e-07 29.8 11.3 7.3e-05 22.8 2.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI36408.1 - 6.9e-06 26.0 11.5 9.3e-05 22.5 1.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KPI36408.1 - 3.7e-05 23.8 1.9 3.7e-05 23.8 1.3 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 KPI36408.1 - 0.00046 20.2 10.4 0.00086 19.4 1.0 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KPI36408.1 - 0.021 14.9 3.6 0.021 14.9 2.5 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KPI36408.1 - 0.48 10.5 6.1 0.85 9.7 4.2 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding PTS_2-RNA PF01885.11 KPI36409.1 - 2.6e-57 193.1 0.0 5.8e-57 192.0 0.0 1.5 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF3542 PF12061.3 KPI36409.1 - 0.096 11.6 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3542) Clr5 PF14420.1 KPI36410.1 - 5.9e-15 54.8 0.0 2.4e-13 49.7 0.0 2.6 2 0 0 2 2 2 1 Clr5 domain TPR_2 PF07719.12 KPI36410.1 - 0.057 13.3 0.4 0.057 13.3 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KPI36410.1 - 0.06 13.2 1.1 0.24 11.3 0.7 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 KPI36410.1 - 3.5 8.3 6.3 0.63 10.6 0.5 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat NmrA PF05368.8 KPI36411.1 - 1.8e-22 79.7 2.4 5.1e-09 35.7 0.0 4.0 2 2 1 3 3 3 3 NmrA-like family CheD PF03975.8 KPI36411.1 - 0.041 13.6 0.1 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 CheD chemotactic sensory transduction FAD_binding_2 PF00890.19 KPI36412.1 - 3.3e-122 408.3 4.6 8.2e-122 407.0 3.2 1.7 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KPI36412.1 - 5.8e-40 136.1 1.0 5.8e-40 136.1 0.7 3.1 3 0 0 3 3 3 1 Fumarate reductase flavoprotein C-term Dynamin_N PF00350.18 KPI36412.1 - 3.4e-17 62.7 0.2 4.3e-15 55.9 0.0 3.0 2 0 0 2 2 2 1 Dynamin family DAO PF01266.19 KPI36412.1 - 1e-08 34.4 0.2 2.5e-06 26.6 0.1 3.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase ABC_tran PF00005.22 KPI36412.1 - 1.4e-05 25.3 0.0 6.8e-05 23.1 0.0 2.3 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.18 KPI36412.1 - 1.8e-05 24.6 0.0 0.001 18.9 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Pyr_redox_2 PF07992.9 KPI36412.1 - 2.1e-05 24.4 3.6 0.003 17.4 0.2 3.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI36412.1 - 0.0011 18.0 2.5 0.0082 15.2 0.2 3.0 3 0 0 3 3 3 1 Thi4 family DUF258 PF03193.11 KPI36412.1 - 0.0045 16.1 0.0 0.025 13.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KPI36412.1 - 0.011 15.7 3.1 0.015 15.2 0.0 2.8 3 1 0 3 3 2 0 AAA ATPase domain GIDA PF01134.17 KPI36412.1 - 0.02 13.7 2.8 0.096 11.5 1.9 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Miro PF08477.8 KPI36412.1 - 0.048 14.1 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Adeno_IVa2 PF02456.10 KPI36412.1 - 0.062 11.9 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_29 PF13555.1 KPI36412.1 - 0.092 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain LysM PF01476.15 KPI36413.1 - 2.1e-08 33.9 0.1 3.1e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 LysM domain Methyltransf_16 PF10294.4 KPI36415.1 - 8.7e-46 155.5 0.0 1.1e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KPI36415.1 - 0.0015 19.1 0.0 0.0025 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI36415.1 - 0.01 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KPI36415.1 - 0.083 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans_2 PF11951.3 KPI36416.1 - 0.0041 15.7 0.0 0.0062 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain BTB PF00651.26 KPI36417.1 - 9e-12 44.9 0.1 3.1e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain TauD PF02668.11 KPI36418.1 - 2.7e-24 86.2 0.1 3.3e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KPI36418.1 - 0.0063 15.4 0.0 0.0098 14.8 0.0 1.2 1 0 0 1 1 1 1 CsiD DUF466 PF04328.8 KPI36418.1 - 0.012 15.4 0.1 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF466) Baculo_E56 PF04639.7 KPI36418.1 - 0.11 11.0 0.2 0.18 10.4 0.1 1.2 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope DUF3402 PF11882.3 KPI36419.1 - 1.7e-123 412.7 0.0 2.3e-123 412.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 KPI36419.1 - 2.1e-71 240.1 0.1 3.1e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein HLH PF00010.21 KPI36420.1 - 4.6e-11 42.2 0.0 1.3e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_hydro_31 PF01055.21 KPI36421.1 - 1.7e-140 468.7 5.1 2.8e-140 468.0 3.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Alk_phosphatase PF00245.15 KPI36421.1 - 2.6e-60 204.2 0.2 3.3e-59 200.6 0.1 2.1 1 1 0 1 1 1 1 Alkaline phosphatase Gal_mutarotas_2 PF13802.1 KPI36421.1 - 9.3e-23 79.8 0.2 2.7e-22 78.3 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Phosphodiest PF01663.17 KPI36421.1 - 1.4e-06 27.8 0.8 3.1e-06 26.7 0.5 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KPI36421.1 - 3.8e-06 26.3 0.1 7e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 KPI36421.1 - 0.0043 15.5 0.0 0.0078 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Got1 PF04178.7 KPI36422.1 - 9.8e-35 119.2 16.2 1.2e-34 118.8 11.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2207 PF09972.4 KPI36422.1 - 0.19 10.2 0.6 0.71 8.3 0.4 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DLH PF01738.13 KPI36423.1 - 2e-17 63.2 0.0 2.6e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KPI36423.1 - 9e-05 22.2 0.0 0.00014 21.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI36423.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Velvet PF11754.3 KPI36424.1 - 1.4e-05 24.8 0.0 2.4e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 Velvet factor p450 PF00067.17 KPI36426.1 - 3.4e-60 203.9 0.0 4e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.15 KPI36428.1 - 8.7e-60 201.6 0.4 8.7e-60 201.6 0.3 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KPI36428.1 - 2.7e-46 157.3 9.6 2.7e-46 157.3 6.6 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KPI36428.1 - 4.1e-28 99.2 0.1 1.3e-27 97.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KPI36428.1 - 2.9e-19 68.7 0.0 5.9e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KPI36428.1 - 1.1e-12 48.5 0.0 3e-12 47.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KPI36428.1 - 5.7e-06 25.6 0.2 4.6e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KPI36428.1 - 1.8e-05 24.4 1.3 4e-05 23.3 0.4 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SMN PF06003.7 KPI36429.1 - 0.058 12.4 5.2 0.27 10.3 0.0 2.6 3 0 0 3 3 3 0 Survival motor neuron protein (SMN) RHD3 PF05879.7 KPI36430.1 - 0 1035.7 0.0 0 1035.5 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KPI36430.1 - 8.1e-09 34.8 0.5 1.4e-08 34.1 0.3 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 KPI36430.1 - 1.3e-05 25.1 0.1 3.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KPI36430.1 - 1.3e-05 25.0 0.0 2.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.1 KPI36430.1 - 0.00047 20.1 0.0 0.0018 18.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KPI36430.1 - 0.0038 17.7 0.1 0.0079 16.6 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 KPI36430.1 - 0.022 13.7 0.1 0.042 12.8 0.1 1.4 1 0 0 1 1 1 0 Septin ABC_ATPase PF09818.4 KPI36430.1 - 0.029 12.9 0.0 5.6 5.4 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF1761 PF08570.5 KPI36432.1 - 4.2e-22 78.4 1.3 4.8e-22 78.3 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) CoA_transf_3 PF02515.12 KPI36433.1 - 1.3e-52 177.7 0.0 1.7e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Glu_synthase PF01645.12 KPI36434.1 - 3.3e-159 529.7 0.1 7.8e-158 525.1 0.0 2.1 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 KPI36434.1 - 1.1e-138 461.8 0.0 1.6e-138 461.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 KPI36434.1 - 2.7e-119 397.6 0.0 6.1e-119 396.5 0.0 1.5 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 KPI36434.1 - 6.2e-66 221.2 1.9 1.2e-65 220.2 1.3 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 KPI36434.1 - 1.1e-22 79.6 0.1 2.7e-22 78.4 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 KPI36434.1 - 7.9e-16 58.5 0.0 7.4e-15 55.3 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI36434.1 - 7.1e-11 42.5 0.7 0.00012 22.1 0.1 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI36434.1 - 1.2e-08 34.8 0.0 4.8e-08 32.8 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KPI36434.1 - 8e-08 32.5 0.0 0.00032 21.0 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KPI36434.1 - 1.2e-06 27.9 0.1 1.8e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 KPI36434.1 - 2.4e-05 22.9 0.3 5e-05 21.9 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 KPI36434.1 - 7e-05 21.8 0.3 0.00059 18.7 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 KPI36434.1 - 0.00028 20.0 0.1 0.0034 16.5 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KPI36434.1 - 0.00033 19.6 0.3 0.00033 19.6 0.2 1.9 2 0 0 2 2 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KPI36434.1 - 0.0007 19.8 2.0 0.35 11.1 0.0 2.9 3 0 0 3 3 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 KPI36434.1 - 0.00084 18.9 0.0 0.033 13.7 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 KPI36434.1 - 0.0012 18.0 0.2 0.0022 17.1 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FMO-like PF00743.14 KPI36434.1 - 0.0013 17.0 0.0 0.053 11.7 0.0 2.7 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Thi4 PF01946.12 KPI36434.1 - 0.0031 16.6 0.3 0.011 14.8 0.0 2.0 2 0 0 2 2 2 1 Thi4 family MADF_DNA_bdg PF10545.4 KPI36434.1 - 0.015 15.4 1.2 0.038 14.1 0.9 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Shikimate_DH PF01488.15 KPI36434.1 - 0.029 14.4 0.2 11 6.1 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 KPI36434.1 - 0.03 14.0 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMN_dh PF01070.13 KPI36434.1 - 0.036 12.9 2.1 0.17 10.7 1.1 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase 2-Hacid_dh_C PF02826.14 KPI36434.1 - 0.051 12.7 0.6 0.11 11.6 0.0 1.8 2 0 0 2 2 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KPI36434.1 - 0.075 12.3 0.1 0.27 10.6 0.1 1.9 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DJ-1_PfpI PF01965.19 KPI36434.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family NAD_binding_9 PF13454.1 KPI36434.1 - 0.11 12.2 0.1 0.41 10.3 0.0 2.0 2 0 0 2 2 1 0 FAD-NAD(P)-binding GATase_6 PF13522.1 KPI36434.1 - 0.12 12.3 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain GIDA PF01134.17 KPI36434.1 - 0.17 10.7 3.0 0.09 11.6 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KPI36434.1 - 1.9 8.1 3.8 0.5 9.9 0.1 2.0 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XPA_C PF05181.7 KPI36436.1 - 7.3e-28 95.9 2.5 1.9e-27 94.5 1.7 1.8 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 KPI36436.1 - 3.6e-06 26.5 1.1 3.6e-06 26.5 0.7 1.8 2 0 0 2 2 2 1 XPA protein N-terminal YhfH PF14149.1 KPI36436.1 - 0.21 11.4 1.9 0.78 9.5 0.1 2.4 2 0 0 2 2 2 0 YhfH-like protein TcdB_N PF12918.2 KPI36436.1 - 0.46 10.5 2.9 1.1 9.3 2.0 1.6 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain ArfGap PF01412.13 KPI36436.1 - 2.3 8.0 7.4 0.25 11.1 0.4 2.5 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.5 KPI36436.1 - 8.4 6.4 8.2 3.1 7.8 0.3 3.1 2 1 1 3 3 3 0 Zinc ribbon domain Pyr_redox_3 PF13738.1 KPI36437.1 - 0.00013 22.1 0.0 0.0025 17.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI36437.1 - 0.00056 19.8 0.0 0.011 15.6 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ketoacyl-synt PF00109.21 KPI36439.1 - 2.1e-56 191.2 1.7 5e-55 186.7 1.2 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KPI36439.1 - 6.3e-42 144.0 0.0 1.3e-41 143.0 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KPI36439.1 - 4e-34 117.0 0.0 1.2e-33 115.4 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 KPI36439.1 - 1.7e-25 90.5 0.0 5.5e-25 88.9 0.0 2.0 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 KPI36439.1 - 2.2e-19 69.5 7.3 3.4e-11 43.2 0.5 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 KPI36439.1 - 2e-07 31.1 0.5 0.0002 21.3 0.0 3.1 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI36439.1 - 4.7e-07 29.6 0.1 0.044 13.5 0.0 3.1 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 KPI36439.1 - 0.00042 19.3 0.0 0.0011 17.9 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Mito_carr PF00153.22 KPI36440.1 - 1.2e-69 230.0 1.5 6.9e-24 83.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein BTB PF00651.26 KPI36441.1 - 4.1e-15 55.7 0.0 8.3e-15 54.7 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Ribosomal_60s PF00428.14 KPI36441.1 - 0.28 11.5 3.7 0.64 10.4 2.5 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DAP3 PF10236.4 KPI36442.1 - 0.052 12.4 0.0 1.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 BTB PF00651.26 KPI36442.1 - 0.083 12.8 0.0 0.19 11.7 0.0 1.6 1 1 0 1 1 1 0 BTB/POZ domain HTH_CodY PF08222.6 KPI36442.1 - 0.12 11.7 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 CodY helix-turn-helix domain Med26 PF08711.6 KPI36444.1 - 1.2e-14 53.5 0.0 5.7e-14 51.3 0.0 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DUF1152 PF06626.7 KPI36445.1 - 0.0024 17.0 2.1 1.2 8.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1152) SUI1 PF01253.17 KPI36447.1 - 2.1e-17 62.7 0.0 4e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Nup84_Nup100 PF04121.8 KPI36448.1 - 4.2e-35 120.5 7.7 2.6e-17 61.8 0.4 3.8 2 1 0 3 3 3 3 Nuclear pore protein 84 / 107 DUF2400 PF09674.5 KPI36448.1 - 0.047 13.3 0.1 0.82 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) HisKA PF00512.20 KPI36448.1 - 0.06 13.3 0.4 3.8 7.5 0.2 3.1 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Aconitase PF00330.15 KPI36448.1 - 0.061 11.7 0.0 0.098 11.1 0.0 1.2 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) Bacillus_HBL PF05791.6 KPI36448.1 - 1.1 8.5 4.5 0.57 9.5 0.1 2.5 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) CPSF73-100_C PF11718.3 KPI36450.1 - 5e-05 22.7 1.9 5e-05 22.7 1.3 2.1 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Imm28 PF15574.1 KPI36450.1 - 0.054 13.0 0.2 0.11 12.0 0.2 1.5 1 0 0 1 1 1 0 Immunity protein 28 Baculo_PEP_C PF04513.7 KPI36450.1 - 0.07 12.9 6.5 0.4 10.4 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Metal_resist PF13801.1 KPI36450.1 - 0.11 12.5 5.6 0.4 10.6 0.2 2.5 2 0 0 2 2 2 0 Heavy-metal resistance IncA PF04156.9 KPI36450.1 - 0.94 9.0 21.9 0.3 10.6 2.8 2.2 2 0 0 2 2 2 0 IncA protein Sec5 PF15469.1 KPI36450.1 - 1.7 8.3 13.6 0.21 11.2 2.7 2.7 1 1 0 2 2 2 0 Exocyst complex component Sec5 DUF948 PF06103.6 KPI36450.1 - 3.1 7.7 7.0 20 5.1 1.4 2.9 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PDDEXK_1 PF12705.2 KPI36450.1 - 7.4 5.8 7.8 0.99 8.7 1.6 2.0 1 1 1 2 2 2 0 PD-(D/E)XK nuclease superfamily IPP-2 PF04979.9 KPI36451.1 - 2.1e-12 47.4 17.5 2.6e-08 34.1 0.9 2.6 1 1 2 3 3 3 2 Protein phosphatase inhibitor 2 (IPP-2) Glyco_transf_20 PF00982.16 KPI36452.1 - 2e-156 521.1 0.0 2.3e-156 520.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 KPI36452.1 - 0.078 12.4 0.0 1.7 8.0 0.0 3.0 4 0 0 4 4 4 0 Glycosyl transferases group 1 SWIRM PF04433.12 KPI36453.1 - 0.13 12.4 0.1 1.2 9.3 0.0 2.3 1 1 1 2 2 2 0 SWIRM domain Ank PF00023.25 KPI36454.1 - 1.7e-20 71.7 1.2 3.4e-12 45.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KPI36454.1 - 2.1e-19 69.6 0.1 8.6e-19 67.6 0.1 1.9 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KPI36454.1 - 3.2e-17 62.1 1.7 1e-10 41.4 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI36454.1 - 1.1e-15 56.2 0.3 3.5e-09 36.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KPI36454.1 - 3.9e-14 52.7 0.0 3.3e-13 49.7 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Velvet PF11754.3 KPI36456.1 - 2e-49 167.9 0.3 2.7e-33 115.2 0.0 2.2 1 1 1 2 2 2 2 Velvet factor Fungal_trans_2 PF11951.3 KPI36458.1 - 1.5e-06 27.0 1.4 2.1e-06 26.5 1.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain CsbD PF05532.7 KPI36459.1 - 0.033 13.8 0.1 0.049 13.3 0.1 1.2 1 0 0 1 1 1 0 CsbD-like Mucin PF01456.12 KPI36459.1 - 2.8 7.7 10.8 3.5 7.3 7.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Cyclase PF04199.8 KPI36460.1 - 1.8e-16 60.3 0.1 3e-16 59.5 0.1 1.3 1 0 0 1 1 1 1 Putative cyclase Tau95 PF09734.4 KPI36462.1 - 2e-44 152.1 0.0 3.1e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit DAGK_cat PF00781.19 KPI36462.1 - 0.026 13.9 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain PAT1 PF09770.4 KPI36464.1 - 5.8 5.0 10.6 10 4.2 7.4 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HIG_1_N PF04588.8 KPI36465.1 - 7.6e-08 31.9 0.5 1.5e-07 31.0 0.4 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region ATP-synt_J PF04911.7 KPI36465.1 - 0.12 11.8 0.2 0.48 9.9 0.0 2.1 2 0 0 2 2 2 0 ATP synthase j chain AIM24 PF01987.12 KPI36466.1 - 3.6e-49 167.1 0.2 4.3e-49 166.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 HD PF01966.17 KPI36467.1 - 0.0022 17.9 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 HD domain BTB PF00651.26 KPI36468.1 - 2e-14 53.4 0.7 7.4e-13 48.4 0.3 2.4 2 1 0 2 2 2 1 BTB/POZ domain NmrA PF05368.8 KPI36469.1 - 6.4e-24 84.4 0.0 9.3e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 KPI36469.1 - 0.00015 21.7 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.1 KPI36469.1 - 0.0055 16.7 0.1 0.02 14.9 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI36469.1 - 0.057 12.8 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI36469.1 - 0.1 11.3 0.1 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Blt1 PF12754.2 KPI36471.1 - 3.4e-24 86.0 3.2 1.2e-22 80.9 2.3 2.0 1 1 0 1 1 1 1 Cell-cycle control medial ring component Med11 PF10280.4 KPI36472.1 - 4.6e-21 75.0 0.0 5.7e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein PapD_C PF02753.12 KPI36472.1 - 0.12 12.2 0.0 0.29 10.9 0.0 1.6 2 0 0 2 2 2 0 Pili assembly chaperone PapD, C-terminal domain GST_N_3 PF13417.1 KPI36473.1 - 9.9e-14 51.3 0.0 2.3e-13 50.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI36473.1 - 7.4e-10 38.6 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KPI36473.1 - 1.3e-05 25.2 0.0 2.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Striatin PF08232.7 KPI36474.1 - 1.2e-33 116.3 7.9 1.2e-33 116.3 5.5 2.3 2 1 0 2 2 2 1 Striatin family WD40 PF00400.27 KPI36474.1 - 1.1e-32 110.6 17.4 6.6e-07 28.9 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KPI36474.1 - 0.00028 20.6 0.0 0.0015 18.2 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Vps54 PF07928.7 KPI36475.1 - 3.8e-44 150.0 3.5 8e-44 149.0 0.1 2.8 3 0 0 3 3 3 1 Vps54-like protein DUF2450 PF10475.4 KPI36475.1 - 8.9e-06 24.8 0.8 8.9e-06 24.8 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) LUC7 PF03194.10 KPI36475.1 - 0.0095 15.4 0.6 0.0095 15.4 0.4 1.8 2 0 0 2 2 2 1 LUC7 N_terminus BLOC1_2 PF10046.4 KPI36475.1 - 0.12 12.4 3.7 0.094 12.8 0.5 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec8_exocyst PF04048.9 KPI36475.1 - 0.12 11.9 5.7 0.041 13.5 1.4 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF3682 PF12446.3 KPI36476.1 - 0.1 12.8 5.2 0.14 12.4 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Cecropin PF00272.14 KPI36476.1 - 0.16 11.5 0.2 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 Cecropin family Mucin PF01456.12 KPI36476.1 - 0.18 11.5 12.9 0.23 11.2 8.9 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.3 KPI36476.1 - 0.73 9.0 5.2 0.79 8.8 3.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal V-ATPase_C PF03223.10 KPI36477.1 - 5.8e-105 351.2 0.0 5.5e-104 348.0 0.0 1.9 1 1 0 1 1 1 1 V-ATPase subunit C KAT11 PF08214.6 KPI36478.1 - 4.5e-80 269.3 0.0 6e-80 268.9 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein Deltaretro_Tax PF05599.6 KPI36478.1 - 0.057 13.7 1.3 0.09 13.0 0.0 2.0 2 0 0 2 2 2 0 Deltaretrovirus Tax protein Exo_endo_phos PF03372.18 KPI36480.1 - 7.9e-14 52.1 0.5 1.3e-13 51.4 0.4 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KPI36480.1 - 2.9e-05 23.6 0.0 6.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Nup54 PF13874.1 KPI36481.1 - 1.9e-32 111.8 2.2 1.9e-32 111.8 1.5 2.4 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 KPI36481.1 - 0.00012 22.2 41.6 0.00033 20.8 28.8 1.7 1 1 0 1 1 1 1 Nucleoporin FG repeat region Fmp27_WPPW PF10359.4 KPI36481.1 - 0.0032 15.9 0.9 0.0032 15.9 0.6 2.0 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Allexi_40kDa PF05549.6 KPI36481.1 - 0.07 12.4 0.2 0.07 12.4 0.2 1.8 2 0 0 2 2 2 0 Allexivirus 40kDa protein TBPIP PF07106.8 KPI36481.1 - 0.1 12.1 4.8 0.18 11.3 0.7 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF826 PF05696.6 KPI36481.1 - 0.46 10.6 2.7 2 8.6 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF826) DUF342 PF03961.8 KPI36481.1 - 1.2 7.4 11.6 0.26 9.6 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 KPI36481.1 - 5.1 6.9 10.8 13 5.6 1.2 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Mito_fiss_reg PF05308.6 KPI36482.1 - 8.4 5.6 8.4 12 5.1 5.8 1.5 1 1 0 1 1 1 0 Mitochondrial fission regulator PNTB PF02233.11 KPI36483.1 - 2.3e-152 507.9 38.2 2e-84 283.9 1.6 2.3 1 1 1 2 2 2 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KPI36483.1 - 4.8e-48 162.8 0.1 1.1e-47 161.7 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KPI36483.1 - 3.1e-46 156.7 0.1 8.2e-46 155.3 0.1 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KPI36483.1 - 3.4e-29 100.8 2.8 3.4e-29 100.8 2.0 5.0 4 1 1 5 5 5 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 KPI36483.1 - 0.0031 16.6 0.1 0.072 12.2 0.0 2.8 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KPI36483.1 - 0.011 15.6 0.1 0.027 14.3 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.17 KPI36483.1 - 0.011 15.4 2.6 0.16 11.7 1.1 3.3 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain NAD_binding_8 PF13450.1 KPI36483.1 - 0.63 10.1 6.8 0.5 10.4 1.2 3.2 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Phage-A118_gp45 PF10653.4 KPI36484.1 - 0.091 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein gp45 of Bacteriophage A118 Gag_spuma PF03276.9 KPI36485.1 - 5.4 5.2 6.9 5.8 5.1 4.8 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DEAD PF00270.24 KPI36486.1 - 6.3e-44 149.4 0.0 1.4e-43 148.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI36486.1 - 1e-23 82.9 0.0 4.5e-23 80.9 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KPI36486.1 - 0.0027 16.5 0.0 0.0049 15.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KPI36486.1 - 0.02 14.7 0.0 0.088 12.6 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1264 PF06884.6 KPI36487.1 - 2.5e-50 170.2 0.2 3.3e-50 169.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) MCM PF00493.18 KPI36488.1 - 3.2e-140 466.6 0.1 4.5e-140 466.1 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KPI36488.1 - 1.3e-17 64.4 0.2 3e-17 63.2 0.2 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KPI36488.1 - 2.4e-06 26.8 0.0 0.00024 20.3 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KPI36488.1 - 4.8e-05 23.1 0.0 0.00012 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KPI36488.1 - 0.00088 18.8 0.1 0.0033 17.0 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KPI36488.1 - 0.032 13.7 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain BTB PF00651.26 KPI36489.1 - 4e-06 26.7 0.0 1.1e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Pkinase PF00069.20 KPI36490.1 - 1.2e-44 152.4 0.0 3.8e-44 150.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI36490.1 - 1.1e-25 90.2 0.0 1.6e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI36490.1 - 0.022 13.7 0.1 0.15 10.9 0.1 1.9 1 1 0 1 1 1 0 Kinase-like DUF2237 PF09996.4 KPI36491.1 - 7.5e-34 115.7 0.1 1.4e-33 114.7 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) SLT_2 PF13406.1 KPI36491.1 - 0.11 11.4 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Transglycosylase SLT domain Tox-HDC PF15656.1 KPI36491.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature Glutaredoxin PF00462.19 KPI36493.1 - 2.7e-20 72.1 0.0 2.3e-17 62.7 0.0 2.8 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.15 KPI36493.1 - 4e-15 55.3 0.0 1.8e-14 53.2 0.0 2.0 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 KPI36493.1 - 0.0044 17.1 0.0 0.055 13.5 0.0 2.4 2 1 1 3 3 3 1 Thioredoxin-like MAP2_projctn PF08377.5 KPI36493.1 - 0.006 14.2 0.0 0.0076 13.8 0.0 1.1 1 0 0 1 1 1 1 MAP2/Tau projection domain Cytokin_check_N PF10407.4 KPI36493.1 - 0.1 12.2 0.1 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus Bac_luciferase PF00296.15 KPI36494.1 - 5.1e-62 209.7 0.2 6.8e-62 209.3 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Glyco_transf_25 PF01755.12 KPI36495.1 - 1.7e-05 24.5 0.0 0.00015 21.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Abhydrolase_6 PF12697.2 KPI36496.1 - 2e-21 76.9 1.5 2.4e-21 76.6 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI36496.1 - 1.1e-13 51.3 0.1 4e-10 39.6 0.2 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI36496.1 - 2.6e-07 30.5 0.0 5.4e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.7 KPI36496.1 - 0.18 11.7 0.7 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Peptidase_S15 PF02129.13 KPI36497.1 - 2.5e-41 141.8 0.2 4e-41 141.2 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KPI36497.1 - 7.3e-30 104.4 0.1 1.1e-29 103.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KPI36497.1 - 3.5e-07 30.3 0.3 5.9e-07 29.6 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI36497.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KPI36497.1 - 0.07 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Dynamin_N PF00350.18 KPI36498.1 - 2.2e-22 79.6 0.0 7e-22 78.0 0.0 1.9 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KPI36498.1 - 2.6e-15 56.0 0.1 2.9e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 KPI36498.1 - 0.00019 21.2 1.1 0.00085 19.1 0.1 2.6 2 1 0 2 2 2 1 Dynamin GTPase effector domain Miro PF08477.8 KPI36498.1 - 0.0012 19.2 0.0 0.005 17.3 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KPI36498.1 - 0.0019 18.1 0.0 0.013 15.4 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KPI36498.1 - 0.015 14.6 0.0 5.9 6.1 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.1 KPI36498.1 - 0.043 13.7 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KPI36498.1 - 0.31 11.3 3.8 0.34 11.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain adh_short PF00106.20 KPI36499.1 - 1.3e-17 64.2 0.0 1.6e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI36499.1 - 1.8e-09 37.7 0.0 2.5e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI36499.1 - 3.8e-05 23.4 0.0 5.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI36499.1 - 0.00026 21.0 0.0 0.00047 20.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 KPI36499.1 - 0.003 17.6 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 KPI36499.1 - 0.01 15.5 0.3 0.02 14.6 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3437 PF11919.3 KPI36499.1 - 0.023 14.3 0.1 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) ApbA PF02558.11 KPI36499.1 - 0.028 13.8 0.0 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF3815 PF12821.2 KPI36499.1 - 0.17 11.8 0.5 12 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3815) Pex19 PF04614.7 KPI36500.1 - 2e-57 194.6 13.6 2e-57 194.6 9.4 2.0 2 1 0 2 2 2 1 Pex19 protein family GET2 PF08690.5 KPI36500.1 - 4.9 6.3 23.0 0.72 9.0 8.9 2.8 2 1 1 3 3 3 0 GET complex subunit GET2 MARVEL PF01284.18 KPI36502.1 - 1e-05 25.3 11.6 1.9e-05 24.5 8.1 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF454 PF04304.8 KPI36502.1 - 0.27 11.2 0.1 0.27 11.2 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF454) DUF202 PF02656.10 KPI36502.1 - 1.2 9.3 6.1 0.21 11.8 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Pkinase PF00069.20 KPI36504.1 - 2.4e-50 171.0 0.0 8.5e-35 120.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KPI36504.1 - 4.7e-22 78.3 0.0 1.3e-21 76.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI36504.1 - 4.3e-06 25.9 0.0 1.8e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KPI36504.1 - 0.00092 19.0 0.7 0.0033 17.1 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family PhoQ_Sensor PF08918.5 KPI36504.1 - 0.18 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoQ Sensor DUF2420 PF10336.4 KPI36505.1 - 2.7e-10 39.8 0.0 6.4e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Fungal_trans PF04082.13 KPI36506.1 - 2.8e-20 72.2 0.4 2.4e-18 65.9 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Fungal_trans PF04082.13 KPI36507.1 - 3.2e-13 49.1 0.4 5.1e-13 48.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI36507.1 - 5.5e-06 26.1 11.5 1e-05 25.3 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG22 PF11700.3 KPI36508.1 - 1.9e-42 145.3 29.6 3.2e-42 144.6 20.5 1.4 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like eIF-3c_N PF05470.7 KPI36509.1 - 4.6e-154 513.7 29.9 4.4e-121 404.8 4.0 4.2 3 2 1 4 4 4 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KPI36509.1 - 8.4e-14 51.7 0.4 3.6e-13 49.7 0.0 2.3 2 0 0 2 2 2 1 PCI domain Baculo_VP91_N PF08475.5 KPI36509.1 - 0.043 13.1 3.5 0.032 13.6 0.8 1.9 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal DUF883 PF05957.8 KPI36509.1 - 0.15 12.4 1.8 17 5.9 0.5 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Transp_cyt_pur PF02133.10 KPI36510.1 - 4e-20 71.7 40.3 5.5e-20 71.3 27.9 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin YqhR PF11085.3 KPI36510.1 - 0.011 15.2 8.4 0.037 13.5 5.8 1.9 1 0 0 1 1 1 0 Conserved membrane protein YqhR GMC_oxred_N PF00732.14 KPI36511.1 - 6.7e-77 258.5 0.0 9.1e-77 258.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI36511.1 - 1.2e-34 119.6 0.5 6.2e-34 117.3 0.3 2.1 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KPI36511.1 - 2.3e-05 23.4 0.0 0.019 13.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KPI36511.1 - 0.00041 19.3 0.0 0.062 12.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KPI36511.1 - 0.015 14.1 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 KPI36511.1 - 0.075 12.1 0.1 0.17 10.9 0.0 1.5 2 0 0 2 2 2 0 Thi4 family EAP30 PF04157.11 KPI36512.1 - 2.3e-52 177.3 0.0 2.7e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Glt_symporter PF03616.9 KPI36512.1 - 0.036 12.5 0.3 0.053 12.0 0.2 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter LigB PF02900.13 KPI36513.1 - 2.9e-20 72.3 0.0 3.3e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PH_8 PF15409.1 KPI36513.1 - 0.045 13.8 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 Pleckstrin homology domain TauD PF02668.11 KPI36514.1 - 1.9e-48 165.4 1.0 2.4e-48 165.0 0.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KPI36514.1 - 0.076 11.9 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 CsiD Molybdopterin PF00384.17 KPI36515.1 - 6.3e-33 114.1 0.0 1.1e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin oxidoreductase DUF2985 PF11204.3 KPI36515.1 - 4.1e-28 96.9 3.3 8.2e-28 95.9 2.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) NADH-G_4Fe-4S_3 PF10588.4 KPI36515.1 - 3.6e-18 64.5 0.1 7.1e-18 63.5 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 KPI36515.1 - 3.5e-07 29.9 0.1 1e-06 28.4 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Molybdopterin PF00384.17 KPI36516.1 - 1.4e-34 119.5 0.0 2.1e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin oxidoreductase DUF1982 PF09326.6 KPI36516.1 - 9.6e-15 54.4 0.0 2e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Ima1_N PF09779.4 KPI36517.1 - 4.2e-30 104.9 6.8 8e-30 104.0 4.7 1.5 1 0 0 1 1 1 1 Ima1 N-terminal domain OrfB_Zn_ribbon PF07282.6 KPI36517.1 - 0.003 17.1 2.7 0.003 17.1 1.8 2.2 3 0 0 3 3 3 1 Putative transposase DNA-binding domain zinc_ribbon_6 PF14599.1 KPI36517.1 - 0.18 11.6 1.8 0.61 9.9 0.6 2.2 2 0 0 2 2 2 0 Zinc-ribbon FYVE PF01363.16 KPI36517.1 - 3.8 7.4 11.5 23 4.9 8.0 2.1 1 1 0 1 1 1 0 FYVE zinc finger UPF0061 PF02696.9 KPI36518.1 - 1.9e-45 155.1 0.0 2.3e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Cullin PF00888.17 KPI36518.1 - 0.0093 14.5 0.2 0.012 14.2 0.1 1.1 1 0 0 1 1 1 1 Cullin family CR6_interact PF10147.4 KPI36518.1 - 0.0099 15.2 0.7 0.017 14.4 0.5 1.3 1 1 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF3296 PF11726.3 KPI36518.1 - 0.095 12.2 1.1 0.15 11.5 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3296) SLAC1 PF03595.12 KPI36519.1 - 2.8e-59 200.4 42.8 3.5e-59 200.1 29.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF2852 PF11014.3 KPI36519.1 - 3.7 7.5 10.3 0.11 12.5 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) Aldedh PF00171.17 KPI36520.1 - 2.4e-155 517.4 1.4 2.7e-155 517.2 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KPI36520.1 - 0.00027 19.7 0.3 0.0033 16.1 0.2 2.1 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Pkinase PF00069.20 KPI36521.1 - 2.4e-36 125.2 0.0 2.8e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI36521.1 - 1e-14 54.2 0.0 1.3e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KPI36521.1 - 0.0061 16.3 0.0 0.35 10.5 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family A_deaminase PF00962.17 KPI36522.1 - 6.1e-50 170.0 0.0 7e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase FAD_binding_3 PF01494.14 KPI36523.1 - 2.2e-16 59.8 0.2 6.7e-13 48.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KPI36523.1 - 2.1e-05 23.5 0.2 0.0041 16.0 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI36523.1 - 0.00049 20.0 0.5 0.0012 18.8 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KPI36523.1 - 0.021 14.9 0.0 0.041 13.9 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI36523.1 - 0.048 13.5 0.4 0.16 11.8 0.3 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.4 KPI36523.1 - 0.054 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain AAA PF00004.24 KPI36524.1 - 1.8e-14 54.0 0.7 2.1e-12 47.3 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 KPI36524.1 - 1.4e-08 34.6 0.2 1.3e-07 31.3 0.1 2.2 1 1 0 1 1 1 1 BCS1 N terminal RuvB_N PF05496.7 KPI36524.1 - 7.5e-06 25.1 0.0 1.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KPI36524.1 - 3.5e-05 24.5 0.0 8.6e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KPI36524.1 - 4.7e-05 23.4 0.2 0.00012 22.0 0.0 1.9 2 1 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.9 KPI36524.1 - 0.00027 20.6 0.0 0.00053 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KPI36524.1 - 0.00088 18.9 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KPI36524.1 - 0.0016 18.3 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KPI36524.1 - 0.0021 18.3 0.0 0.004 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KPI36524.1 - 0.0029 17.6 0.1 0.0093 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KPI36524.1 - 0.0047 17.0 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KPI36524.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 KPI36524.1 - 0.028 13.8 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.1 KPI36524.1 - 0.03 13.9 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KPI36524.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.8 KPI36524.1 - 0.11 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 KPI36524.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain GST_N_3 PF13417.1 KPI36525.1 - 3.1e-06 27.3 0.1 7.1e-06 26.1 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI36525.1 - 0.0001 22.2 0.0 0.00021 21.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KPI36525.1 - 0.00029 20.6 0.0 0.003 17.4 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KPI36525.1 - 0.052 13.7 0.0 0.17 12.0 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain FAD_binding_3 PF01494.14 KPI36526.1 - 3.9e-17 62.3 0.4 2.7e-07 29.9 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KPI36526.1 - 0.001 19.0 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KPI36526.1 - 0.017 13.9 0.0 0.049 12.4 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.1 KPI36526.1 - 0.11 12.3 0.4 0.71 9.6 0.1 2.2 1 1 1 2 2 2 0 FAD-NAD(P)-binding Mid2 PF04478.7 KPI36527.1 - 0.00047 19.6 4.3 0.00047 19.6 3.0 2.3 2 1 1 3 3 3 1 Mid2 like cell wall stress sensor DUF533 PF04391.7 KPI36527.1 - 0.0097 15.2 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF533) FAD_binding_3 PF01494.14 KPI36528.1 - 1.3e-19 70.4 0.0 2.3e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ADC PF06314.6 KPI36528.1 - 1.5e-17 63.7 0.0 2.9e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NAD_binding_8 PF13450.1 KPI36528.1 - 5.7e-07 29.4 0.4 1.7e-06 27.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI36528.1 - 5.7e-05 22.1 2.2 0.00095 18.1 0.8 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI36528.1 - 7.1e-05 21.8 1.8 0.00012 21.0 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 KPI36528.1 - 0.00016 20.4 0.8 0.042 12.4 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 KPI36528.1 - 0.00088 19.2 0.0 0.0037 17.1 0.1 2.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI36528.1 - 0.001 18.0 0.1 0.0019 17.1 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 KPI36528.1 - 0.0033 15.9 0.2 0.0062 15.0 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KPI36528.1 - 0.019 14.0 0.7 0.23 10.4 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 KPI36528.1 - 0.031 13.3 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KPI36528.1 - 0.034 14.5 0.2 0.083 13.3 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI36528.1 - 0.31 10.7 2.4 14 5.3 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Fungal_trans_2 PF11951.3 KPI36529.1 - 1.6e-06 27.0 0.0 2.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_3 PF00202.16 KPI36530.1 - 8.4e-90 301.0 0.0 9.9e-90 300.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III adh_short PF00106.20 KPI36531.1 - 1.2e-22 80.6 0.8 1.8e-21 76.7 0.6 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI36531.1 - 5.4e-18 65.6 2.0 7e-17 61.9 1.4 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI36531.1 - 7.2e-10 38.8 0.1 2.8e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KPI36531.1 - 0.00016 21.2 0.1 0.0017 17.8 0.0 2.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KPI36531.1 - 0.0055 15.6 0.0 0.007 15.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein UDPG_MGDP_dh_C PF03720.10 KPI36531.1 - 0.02 15.0 0.1 0.083 13.0 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain KaiC PF06745.8 KPI36531.1 - 0.067 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 KaiC Peripla_BP_4 PF13407.1 KPI36531.1 - 0.083 12.2 0.8 0.17 11.1 0.1 1.8 2 0 0 2 2 2 0 Periplasmic binding protein domain Actin PF00022.14 KPI36532.1 - 9.8e-26 90.0 0.0 7.4e-17 60.8 0.0 2.7 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KPI36532.1 - 6.4e-06 24.9 0.5 1.1e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 MreB/Mbl protein DUF2114 PF09887.4 KPI36532.1 - 0.24 9.7 0.1 0.36 9.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Ribosomal_S19e PF01090.14 KPI36533.1 - 7.2e-55 184.2 0.1 8.2e-55 184.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e MFS_1 PF07690.11 KPI36534.1 - 3.1e-37 128.0 27.9 6.1e-36 123.8 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI36534.1 - 3.2e-10 39.1 11.0 3.2e-10 39.1 7.6 2.0 1 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KPI36534.1 - 2.4e-08 32.6 4.8 3.9e-08 31.9 3.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 KPI36535.1 - 5.6e-67 226.2 0.0 6.3e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CDP-OH_P_transf PF01066.16 KPI36536.1 - 5.2e-14 52.3 12.2 5.2e-14 52.3 8.5 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ADH_zinc_N PF00107.21 KPI36537.1 - 7.1e-21 74.1 0.1 1.5e-20 73.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI36537.1 - 2.9e-17 62.3 1.4 5.5e-17 61.5 1.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pkinase PF00069.20 KPI36538.1 - 1.1e-35 123.0 0.0 2.1e-19 69.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KPI36538.1 - 1.5e-12 47.1 0.0 3.3e-06 26.3 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KPI36538.1 - 5.7e-05 22.9 3.0 5.8e-05 22.9 1.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family ADH_zinc_N PF00107.21 KPI36539.1 - 2.8e-10 39.8 0.1 4.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI36539.1 - 0.064 14.1 0.1 0.095 13.5 0.1 1.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Fungal_trans PF04082.13 KPI36540.1 - 1.1e-12 47.3 0.0 1.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HLH PF00010.21 KPI36541.1 - 1.5e-13 50.1 0.1 3e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain WD40 PF00400.27 KPI36542.1 - 1.1e-14 53.6 2.7 0.46 10.4 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat NTR2 PF15458.1 KPI36543.1 - 5.3e-38 130.7 8.1 5.3e-36 124.1 5.6 2.3 1 1 0 1 1 1 1 Nineteen complex-related protein 2 Bim_N PF06773.6 KPI36543.1 - 0.013 15.2 0.1 0.047 13.4 0.0 2.0 1 0 0 1 1 1 0 Bim protein N-terminus p450 PF00067.17 KPI36545.1 - 2e-57 194.7 0.0 2.5e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GPP34 PF05719.6 KPI36545.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) MFS_1 PF07690.11 KPI36546.1 - 3.7e-31 108.1 54.4 6.6e-31 107.2 33.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI36546.1 - 1.5e-06 27.0 12.2 1.5e-06 27.0 8.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Papilloma_E5A PF05776.7 KPI36546.1 - 5.4 7.2 8.4 1.5 8.9 1.2 2.7 2 0 0 2 2 2 0 Papillomavirus E5A protein Sugar_tr PF00083.19 KPI36547.1 - 6e-29 100.9 18.7 7e-29 100.6 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI36547.1 - 5.8e-09 35.1 7.7 6.3e-09 35.0 5.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DNA_pol_B PF00136.16 KPI36548.1 - 1.8e-113 379.7 4.9 2.7e-113 379.2 3.4 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KPI36548.1 - 1.3e-62 210.4 5.6 2.5e-62 209.5 3.9 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 KPI36548.1 - 1.2e-36 126.2 0.0 2.1e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KPI36548.1 - 6.6e-26 89.9 9.6 1.6e-25 88.7 4.1 2.9 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal Fasciclin PF02469.17 KPI36549.1 - 3.2e-32 111.2 1.9 4.1e-17 62.3 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain UPF0061 PF02696.9 KPI36550.1 - 7.8e-57 192.6 0.0 9.8e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF1127 PF06568.6 KPI36550.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) PEARLI-4 PF05278.7 KPI36551.1 - 0.012 15.0 9.4 0.47 9.7 0.5 2.1 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) NYD-SP28_assoc PF14775.1 KPI36551.1 - 0.031 13.9 0.4 0.067 12.8 0.3 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Med9 PF07544.8 KPI36551.1 - 0.035 13.8 3.3 0.3 10.8 0.4 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CENP-F_leu_zip PF10473.4 KPI36551.1 - 0.052 13.4 7.3 0.16 11.8 4.8 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 KPI36551.1 - 0.056 13.2 0.9 3.5 7.3 0.0 2.3 1 1 1 2 2 2 0 Laminin Domain II 4HB_MCP_1 PF12729.2 KPI36551.1 - 0.091 12.1 4.9 0.15 11.4 3.4 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction APG6 PF04111.7 KPI36551.1 - 0.11 11.4 8.0 2.8 6.9 2.1 1.9 1 1 0 1 1 1 0 Autophagy protein Apg6 Herpes_UL6 PF01763.11 KPI36551.1 - 0.14 10.2 2.4 0.17 10.0 1.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DivIVA PF05103.8 KPI36551.1 - 0.19 11.7 5.4 0.25 11.4 0.3 2.4 1 1 1 2 2 2 0 DivIVA protein HAUS6_N PF14661.1 KPI36551.1 - 0.38 10.0 3.8 0.28 10.4 0.3 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Cep57_MT_bd PF06657.8 KPI36551.1 - 0.42 10.5 3.0 0.98 9.4 0.2 2.5 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF972 PF06156.8 KPI36551.1 - 0.55 10.5 3.3 3.7 7.9 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Sin3_corepress PF08295.7 KPI36551.1 - 0.58 9.9 4.2 2.1 8.1 0.2 2.7 2 1 1 3 3 3 0 Sin3 family co-repressor DUF4164 PF13747.1 KPI36551.1 - 0.92 9.6 9.9 11 6.2 4.9 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Fungal_trans_2 PF11951.3 KPI36552.1 - 1.4e-12 46.9 0.7 5.7e-12 44.9 0.5 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain HgmA PF04209.8 KPI36553.1 - 7.9e-175 581.2 0.0 9.1e-175 581.0 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DUF1052 PF06319.7 KPI36553.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1052) ApbA PF02558.11 KPI36554.1 - 6.8e-27 93.7 0.1 9.5e-27 93.2 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KPI36554.1 - 5.9e-24 84.4 0.0 9.9e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal UDPG_MGDP_dh_N PF03721.9 KPI36554.1 - 0.054 12.8 0.4 0.089 12.1 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PA14_2 PF10528.4 KPI36555.1 - 1.3e-12 47.6 0.2 7.2e-12 45.2 0.0 2.5 2 0 0 2 2 2 1 GLEYA domain PA14 PF07691.7 KPI36555.1 - 0.00019 21.1 0.1 0.00091 18.8 0.0 2.2 2 0 0 2 2 2 1 PA14 domain AstA PF04958.7 KPI36555.1 - 0.92 7.8 0.0 2.3 6.5 0.0 1.6 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit DUF2080 PF09853.4 KPI36555.1 - 1.1 9.0 9.8 4.1 7.2 0.1 5.2 5 0 0 5 5 5 0 Putative transposon-encoded protein (DUF2080) Pkinase PF00069.20 KPI36556.1 - 1e-52 178.8 0.0 2.3e-52 177.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI36556.1 - 6e-24 84.5 0.1 1.9e-23 82.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KPI36556.1 - 6.1e-06 26.1 7.9 0.00055 19.7 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KPI36556.1 - 0.0027 17.0 0.2 0.012 14.9 0.2 2.0 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 KPI36556.1 - 0.063 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) Pyr_redox_3 PF13738.1 KPI36558.1 - 2.7e-26 92.9 0.0 4.3e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI36558.1 - 5.4e-16 57.8 0.0 1.9e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI36558.1 - 1.8e-08 34.2 0.0 5.3e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI36558.1 - 2.5e-08 34.0 0.0 3.3e-07 30.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI36558.1 - 2.8e-06 26.4 0.0 0.00022 20.2 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KPI36558.1 - 1.9e-05 23.7 0.1 0.00065 18.7 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KPI36558.1 - 3.4e-05 23.6 0.5 0.0056 16.4 0.2 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KPI36558.1 - 0.00049 19.2 0.1 0.0031 16.6 0.0 2.0 1 1 1 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KPI36558.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 KPI36558.1 - 0.052 12.3 0.0 0.089 11.6 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KPI36558.1 - 0.068 12.2 0.6 0.19 10.7 0.1 1.9 3 0 0 3 3 3 0 Thi4 family 2-Hacid_dh_C PF02826.14 KPI36558.1 - 0.071 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 KPI36558.1 - 0.11 10.9 0.2 0.65 8.4 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 KPI36558.1 - 0.19 12.1 0.3 1.3 9.5 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BCAS2 PF05700.6 KPI36559.1 - 4.3e-48 163.7 2.2 4.5e-48 163.6 1.5 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.3 KPI36559.1 - 0.026 14.2 0.4 0.026 14.2 0.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spore_III_AB PF09548.5 KPI36559.1 - 0.051 13.3 1.2 0.089 12.5 0.7 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) HDAC4_Gln PF12203.3 KPI36559.1 - 0.11 12.4 1.7 1.4 8.9 0.2 2.2 2 0 0 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 Ly49 PF08391.5 KPI36559.1 - 0.15 12.1 0.2 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4407 PF14362.1 KPI36559.1 - 0.86 8.5 5.3 1.3 7.8 3.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PSK_trans_fac PF07704.6 KPI36559.1 - 1.4 9.5 9.3 1.3 9.8 0.2 2.9 1 1 1 3 3 3 0 Rv0623-like transcription factor NAD_binding_8 PF13450.1 KPI36560.1 - 7.2e-08 32.3 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI36560.1 - 0.0004 19.3 1.0 0.00096 18.1 0.7 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI36560.1 - 0.0047 15.8 0.2 0.0098 14.7 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KPI36560.1 - 0.01 15.6 0.2 0.061 13.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KPI36560.1 - 0.012 14.7 0.1 0.019 14.0 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KPI36560.1 - 0.016 13.6 0.1 0.029 12.8 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KPI36560.1 - 0.028 13.5 0.3 0.058 12.4 0.2 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 KPI36560.1 - 0.21 10.5 0.4 0.36 9.8 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Formyl_trans_N PF00551.14 KPI36561.1 - 1.3e-26 93.2 0.0 1.8e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase FAD_binding_3 PF01494.14 KPI36562.1 - 9.2e-17 61.1 0.4 4.7e-16 58.7 0.3 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KPI36562.1 - 3.1e-05 23.9 0.1 8.8e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KPI36562.1 - 0.00019 20.4 0.0 0.0021 17.0 0.0 2.2 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.19 KPI36562.1 - 0.00042 19.3 0.0 0.32 9.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 KPI36562.1 - 0.00044 19.4 0.0 0.00088 18.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KPI36562.1 - 0.00045 20.0 0.0 0.00088 19.0 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KPI36562.1 - 0.013 14.0 0.0 0.02 13.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 KPI36562.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI36562.1 - 0.051 13.9 0.0 0.23 11.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI36562.1 - 0.077 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KPI36562.1 - 0.14 11.6 0.1 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KPI36562.1 - 0.14 11.8 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus KOW PF00467.24 KPI36564.1 - 7.7e-06 25.4 3.4 2.7e-05 23.7 2.3 2.0 1 0 0 1 1 1 1 KOW motif Collagen PF01391.13 KPI36566.1 - 0.006 16.0 4.9 0.014 14.9 3.4 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Ribosomal_L30_N PF08079.7 KPI36567.1 - 8.7e-25 86.5 17.9 1.6e-24 85.6 12.4 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KPI36567.1 - 4.9e-19 67.6 3.0 6.4e-19 67.2 1.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Aminotran_3 PF00202.16 KPI36568.1 - 2.5e-10 39.7 0.0 2.7e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III adh_short PF00106.20 KPI36569.1 - 1.2e-19 70.7 5.6 5.3e-19 68.7 3.9 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI36569.1 - 1.5e-17 64.2 0.1 6.4e-17 62.1 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI36569.1 - 4.3e-09 36.2 0.6 7.5e-09 35.4 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI36569.1 - 0.00011 21.7 0.1 0.00013 21.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KPI36569.1 - 0.00024 20.8 0.3 0.00035 20.2 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KPI36569.1 - 0.01 15.8 0.8 0.022 14.7 0.5 1.5 1 0 0 1 1 1 0 NADH(P)-binding DUF3456 PF11938.3 KPI36569.1 - 0.065 13.2 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP Cupin_2 PF07883.6 KPI36570.1 - 0.00012 21.4 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KPI36570.1 - 0.0081 15.5 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) MFS_1 PF07690.11 KPI36571.1 - 1.4e-31 109.4 41.0 5.8e-29 100.9 20.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF221 PF02714.10 KPI36572.1 - 3e-79 266.2 20.9 3e-79 266.2 14.5 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KPI36572.1 - 2.3e-37 127.9 1.3 2.3e-37 127.9 0.9 3.1 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KPI36572.1 - 7.5e-16 57.7 0.0 1.7e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF3861 PF12977.2 KPI36573.1 - 0.013 15.5 0.2 0.02 14.9 0.1 1.4 1 1 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3861) Saccharop_dh_N PF04455.7 KPI36573.1 - 0.015 15.4 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region Alpha-amylase PF00128.19 KPI36574.1 - 1.3e-96 323.6 0.3 2.3e-96 322.8 0.2 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KPI36574.1 - 1.6e-05 23.9 0.1 3.6e-05 22.8 0.0 1.5 2 0 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme Alpha-amylase_C PF02806.13 KPI36574.1 - 0.0024 17.9 0.0 0.0085 16.2 0.0 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Glyco_hydro_42C PF08533.5 KPI36574.1 - 0.0032 16.9 0.8 0.019 14.4 0.0 2.8 4 0 0 4 4 4 1 Beta-galactosidase C-terminal domain Herpes_U30 PF04523.8 KPI36575.1 - 0.016 12.7 0.3 0.028 11.9 0.2 1.3 1 0 0 1 1 1 0 Herpes virus tegument protein U30 MFS_1 PF07690.11 KPI36576.1 - 3.4e-32 111.5 37.7 3.4e-32 111.5 26.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KPI36578.1 - 9.6e-60 202.4 23.3 1.2e-59 202.1 16.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI36578.1 - 7.5e-21 74.2 51.1 1.2e-19 70.2 35.2 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily MmgE_PrpD PF03972.9 KPI36579.1 - 1.4e-67 227.7 1.6 1.7e-67 227.5 1.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family MFS_1 PF07690.11 KPI36580.1 - 2.7e-32 111.8 48.2 2.7e-32 111.8 33.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI36580.1 - 7.8e-08 31.3 14.5 7.8e-08 31.3 10.0 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KPI36580.1 - 1.9e-06 26.3 17.3 3e-06 25.7 12.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KPI36580.1 - 0.03 12.3 3.7 0.017 13.2 0.7 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2077 PF09850.4 KPI36581.1 - 0.062 12.7 0.3 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF3047 PF11249.3 KPI36582.1 - 3.1e-28 98.3 0.2 4.5e-28 97.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3047) SNF2_N PF00176.18 KPI36583.1 - 5.6e-68 228.9 0.0 8.1e-68 228.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KPI36583.1 - 4.2e-14 52.1 0.0 1.1e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2824 PF11039.3 KPI36583.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) Img2 PF05046.9 KPI36583.1 - 0.086 13.0 0.1 0.37 11.0 0.1 2.1 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) CP12 PF02672.10 KPI36584.1 - 0.05 14.0 2.6 0.05 14.0 1.8 2.2 2 0 0 2 2 2 0 CP12 domain HpcH_HpaI PF03328.9 KPI36585.1 - 5.6e-42 143.1 0.0 7.3e-42 142.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KPI36585.1 - 4.9e-12 45.3 0.2 8.5e-07 28.0 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold NAD_binding_10 PF13460.1 KPI36586.1 - 2.7e-23 82.9 0.0 9.8e-23 81.1 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KPI36586.1 - 1e-06 28.1 0.1 4.5e-06 26.0 0.0 2.0 2 1 0 2 2 2 1 NmrA-like family Fungal_trans PF04082.13 KPI36587.1 - 2.7e-24 85.4 0.0 5.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain HOASN PF14515.1 KPI36587.1 - 0.068 13.5 0.2 0.3 11.4 0.0 2.2 2 1 1 3 3 3 0 Haem-oxygenase-associated N-terminal helices Acetyltransf_3 PF13302.1 KPI36588.1 - 1.2e-05 25.4 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Methyltransf_23 PF13489.1 KPI36589.1 - 2.6e-23 82.4 0.0 4.8e-23 81.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI36589.1 - 6.2e-12 45.8 0.0 1.5e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI36589.1 - 1.1e-09 38.8 0.0 2e-08 34.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI36589.1 - 7.5e-09 35.3 0.0 4.1e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI36589.1 - 2e-08 34.6 0.0 5.8e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI36589.1 - 3.3e-07 30.5 0.0 1.3e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI36589.1 - 0.00015 21.8 0.0 0.00038 20.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI36589.1 - 0.0016 17.6 0.0 0.015 14.4 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KPI36589.1 - 0.0017 17.8 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 KPI36589.1 - 0.0024 16.9 0.0 0.013 14.5 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.8 KPI36589.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 KPI36589.1 - 0.023 13.7 0.0 0.044 12.8 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.7 KPI36589.1 - 0.028 13.9 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.9 KPI36589.1 - 0.029 13.7 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 KPI36589.1 - 0.072 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF3889 PF13028.1 KPI36589.1 - 0.12 12.0 0.0 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3889) p450 PF00067.17 KPI36590.1 - 1.3e-61 208.5 0.0 2.7e-61 207.4 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 FAA_hydrolase PF01557.13 KPI36590.1 - 2e-45 154.8 0.0 4.3e-45 153.8 0.0 1.5 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KPI36590.1 - 5.2e-22 77.8 0.0 1.1e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal zf-MYND PF01753.13 KPI36591.1 - 3.1e-12 46.1 12.5 3.1e-12 46.1 8.7 1.8 2 0 0 2 2 2 1 MYND finger Glyco_hydro_42M PF08532.5 KPI36591.1 - 0.071 12.2 0.1 0.23 10.5 0.1 1.8 1 1 0 1 1 1 0 Beta-galactosidase trimerisation domain Yeast_MT PF11403.3 KPI36591.1 - 0.077 13.1 5.4 0.23 11.6 3.8 1.8 1 0 0 1 1 1 0 Yeast metallothionein RE_ApaLI PF09499.5 KPI36591.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease zf-H2C2_2 PF13465.1 KPI36592.1 - 8.3e-13 47.9 11.3 4.6e-08 32.9 0.2 3.8 3 1 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KPI36592.1 - 1.8e-12 46.8 10.4 1.1e-05 25.4 1.6 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI36592.1 - 6.1e-11 41.8 12.2 3.3e-05 23.9 1.6 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KPI36592.1 - 3.7e-06 26.9 5.0 0.077 13.1 0.2 3.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KPI36592.1 - 2.3e-05 24.4 1.6 0.0093 16.1 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KPI36592.1 - 0.082 13.0 2.0 0.15 12.1 1.4 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.17 KPI36592.1 - 0.92 9.6 3.3 6.4 6.9 2.3 2.1 1 1 0 1 1 1 0 LIM domain zf-BED PF02892.10 KPI36592.1 - 1.5 8.6 4.8 4.9 6.9 0.9 2.6 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 KPI36592.1 - 1.7 8.6 8.2 20 5.2 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Phos_pyr_kin PF08543.7 KPI36594.1 - 2e-49 168.0 0.0 3.8e-49 167.1 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KPI36594.1 - 9.6e-49 165.9 0.1 1.3e-48 165.5 0.1 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 KPI36594.1 - 0.033 13.3 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 pfkB family carbohydrate kinase DUF1707 PF08044.6 KPI36594.1 - 0.13 12.0 1.4 0.29 10.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) zf-C2H2 PF00096.21 KPI36596.1 - 1.1e-13 50.6 21.7 2e-05 24.6 0.9 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI36596.1 - 4.4e-10 39.1 17.5 0.0076 16.5 0.3 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger Peptidase_M1 PF01433.15 KPI36596.1 - 3.4e-07 29.7 0.1 0.14 11.2 0.1 3.5 2 1 0 3 3 3 2 Peptidase family M1 zf-C2H2_6 PF13912.1 KPI36596.1 - 0.0048 16.7 17.5 0.42 10.5 0.6 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KPI36596.1 - 0.0097 16.1 22.3 1.4 9.3 0.7 5.4 5 0 0 5 5 5 2 Zinc-finger double domain zf-met PF12874.2 KPI36596.1 - 0.17 12.1 8.0 14 6.1 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KPI36596.1 - 2 8.6 8.6 4.2 7.6 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding RRN7 PF11781.3 KPI36596.1 - 2.9 7.4 8.7 9.5 5.8 0.1 3.7 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 Mu-like_Com PF10122.4 KPI36596.1 - 4.3 6.4 10.3 14 4.8 0.2 3.8 3 0 0 3 3 3 0 Mu-like prophage protein Com XPA_N PF01286.13 KPI36596.1 - 4.8 6.9 7.6 22 4.8 0.2 3.3 3 0 0 3 3 3 0 XPA protein N-terminal DUF3133 PF11331.3 KPI36596.1 - 9.5 5.8 11.4 5.5 6.6 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) LSM PF01423.17 KPI36598.1 - 2.3e-17 62.2 0.1 2.7e-17 62.0 0.1 1.0 1 0 0 1 1 1 1 LSM domain Sugar_tr PF00083.19 KPI36599.1 - 1.6e-99 333.5 30.9 1.8e-99 333.3 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI36599.1 - 2e-24 86.0 63.3 3.9e-23 81.7 23.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.17 KPI36600.1 - 3.9e-05 22.1 0.0 0.036 12.4 0.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Glyco_transf_34 PF05637.7 KPI36601.1 - 2.6e-12 46.7 0.0 3.6e-06 26.6 0.0 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family ER_lumen_recept PF00810.13 KPI36602.1 - 8.1e-52 175.6 4.0 1.3e-51 174.9 2.8 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor AA_permease_2 PF13520.1 KPI36603.1 - 7.8e-49 166.3 55.2 9.7e-49 166.0 38.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI36603.1 - 1.7e-17 62.9 45.7 2.3e-17 62.5 31.7 1.0 1 0 0 1 1 1 1 Amino acid permease Cupin_1 PF00190.17 KPI36604.1 - 3.7e-17 62.0 0.0 4.9e-11 42.2 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KPI36604.1 - 7e-08 31.8 0.4 0.014 14.8 0.0 2.7 2 1 0 2 2 2 2 Cupin domain NmrA PF05368.8 KPI36605.1 - 5.4e-16 58.5 0.0 7e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI36605.1 - 4.9e-08 33.1 0.6 6.9e-08 32.7 0.4 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KPI36605.1 - 0.0026 16.7 0.3 0.0066 15.4 0.0 1.8 3 0 0 3 3 3 1 Male sterility protein Semialdhyde_dh PF01118.19 KPI36605.1 - 0.0084 16.4 1.3 0.047 13.9 0.3 2.7 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KPI36605.1 - 0.036 13.7 0.3 0.12 12.0 0.1 1.9 2 0 0 2 2 2 0 KR domain Epimerase PF01370.16 KPI36605.1 - 0.13 11.7 0.2 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Alg14 PF08660.6 KPI36606.1 - 3.6e-46 157.2 0.0 5.1e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_trans_4_4 PF13579.1 KPI36606.1 - 0.027 14.5 0.0 0.052 13.6 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain zf-CCCH PF00642.19 KPI36607.1 - 4.8 6.9 6.8 2.1 8.1 0.1 3.0 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MR_MLE_C PF13378.1 KPI36608.1 - 2.7e-29 101.3 0.1 5.3e-29 100.4 0.1 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KPI36608.1 - 3.9e-23 81.6 0.1 1.7e-21 76.3 0.0 2.7 3 0 0 3 3 3 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 KPI36608.1 - 1e-12 48.4 0.3 2.3e-12 47.2 0.2 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Kelch_5 PF13854.1 KPI36609.1 - 7.1e-20 70.5 8.1 1.4e-09 37.6 0.0 5.0 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.1 KPI36609.1 - 2.9e-12 46.3 9.4 1.1e-06 28.6 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 KPI36609.1 - 4e-11 42.4 16.1 0.00061 19.5 0.0 6.1 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 KPI36609.1 - 1.2e-07 31.5 22.6 0.22 11.7 0.3 6.3 5 2 1 6 6 6 5 Kelch motif Kelch_2 PF07646.10 KPI36609.1 - 1.7e-06 27.5 5.5 0.0099 15.6 0.2 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 KPI36609.1 - 0.0038 16.7 5.6 0.38 10.3 0.0 4.7 5 0 0 5 5 5 1 Kelch motif SKG6 PF08693.5 KPI36609.1 - 0.016 14.5 0.4 0.047 13.0 0.3 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain XRN_N PF03159.13 KPI36610.1 - 2.4e-102 341.3 0.5 3.9e-102 340.6 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Thioredox_DsbH PF03190.10 KPI36611.1 - 1.4e-65 219.9 0.0 3.2e-65 218.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 KPI36611.1 - 4.6e-08 32.9 0.0 8.2e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_9 PF00759.14 KPI36611.1 - 0.0066 15.4 2.9 0.01 14.7 2.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 GlcNAc_2-epim PF07221.6 KPI36611.1 - 0.041 12.9 0.0 0.079 11.9 0.0 1.4 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) DUF1546 PF07571.8 KPI36612.1 - 2e-29 101.5 0.1 4.6e-29 100.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 KPI36612.1 - 2e-21 75.6 0.1 4.2e-21 74.6 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) GnsAB PF08178.6 KPI36612.1 - 0.0062 16.1 0.7 0.11 12.1 0.3 2.5 2 0 0 2 2 2 1 GnsA/GnsB family Laminin_I PF06008.9 KPI36613.1 - 0.0017 17.7 0.2 0.0017 17.7 0.2 4.7 3 2 1 4 4 4 1 Laminin Domain I Reo_sigmaC PF04582.7 KPI36613.1 - 0.015 14.4 36.6 0.18 10.9 3.4 5.8 2 2 3 5 5 5 0 Reovirus sigma C capsid protein CCDC-167 PF15188.1 KPI36613.1 - 0.079 12.9 0.3 0.079 12.9 0.2 6.8 5 1 2 8 8 8 0 Coiled-coil domain-containing protein 167 Filament PF00038.16 KPI36613.1 - 0.11 11.9 46.8 0.44 9.9 1.6 5.3 2 2 1 3 3 3 0 Intermediate filament protein Med28 PF11594.3 KPI36613.1 - 0.12 12.6 10.8 0.12 12.5 1.4 4.0 3 1 0 3 3 3 0 Mediator complex subunit 28 IncA PF04156.9 KPI36613.1 - 0.32 10.5 43.5 1.2 8.6 6.6 5.6 3 2 2 5 5 5 0 IncA protein Myosin_tail_1 PF01576.14 KPI36613.1 - 0.45 8.1 45.2 1.6 6.3 0.2 4.0 3 2 0 3 3 3 0 Myosin tail IFT57 PF10498.4 KPI36613.1 - 4.2 6.0 49.0 0.0062 15.3 4.7 5.4 3 2 3 6 6 6 0 Intra-flagellar transport protein 57 DUF972 PF06156.8 KPI36613.1 - 4.6 7.6 39.8 0.42 10.9 0.2 7.9 4 2 2 7 7 7 0 Protein of unknown function (DUF972) DASH_Dam1 PF08653.5 KPI36613.1 - 5.8 6.7 6.8 36 4.2 0.1 4.6 5 0 0 5 5 5 0 DASH complex subunit Dam1 Hemerythrin PF01814.18 KPI36613.1 - 6.3 6.9 21.6 18 5.4 0.3 5.7 4 2 2 6 6 6 0 Hemerythrin HHE cation binding domain DUF1664 PF07889.7 KPI36613.1 - 9.1 6.0 40.2 2.3 8.0 0.2 7.0 5 2 2 7 7 7 0 Protein of unknown function (DUF1664) ADH_N PF08240.7 KPI36614.1 - 2e-27 95.1 5.6 4e-27 94.1 3.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI36614.1 - 7.1e-23 80.5 0.5 1.7e-22 79.3 0.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KPI36614.1 - 2e-06 27.3 0.0 3.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.1 KPI36614.1 - 0.00045 21.1 0.3 0.0011 19.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KPI36614.1 - 0.00087 18.8 0.6 0.0016 18.0 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain p450 PF00067.17 KPI36615.1 - 3.3e-82 276.4 0.0 4.1e-82 276.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Vps26 PF03643.10 KPI36616.1 - 2.5e-130 433.2 0.5 2.9e-130 433.0 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KPI36616.1 - 0.00038 20.2 0.6 1.4 8.6 0.0 3.6 3 1 1 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KPI36616.1 - 0.058 13.4 0.0 0.37 10.8 0.0 2.2 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Ceramidase PF05875.7 KPI36617.1 - 8.7e-47 159.4 0.0 1.1e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Ceramidase LVIVD PF08309.6 KPI36618.1 - 1.3e-05 24.0 1.7 0.36 9.8 0.0 4.1 4 0 0 4 4 4 2 LVIVD repeat ADH_N PF08240.7 KPI36619.1 - 7.4e-34 115.7 0.6 1.2e-33 115.0 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI36619.1 - 3e-26 91.4 0.6 2.6e-25 88.4 0.1 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI36619.1 - 6.3e-10 40.0 0.2 1.4e-09 38.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_26 PF13659.1 KPI36619.1 - 0.11 12.5 0.1 0.53 10.3 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain 3HCDH_N PF02737.13 KPI36619.1 - 0.14 11.8 0.8 0.24 11.0 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Metallophos PF00149.23 KPI36620.1 - 1e-12 47.9 1.6 2.1e-12 46.8 1.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KPI36620.1 - 9.9e-07 28.7 1.1 1.6e-06 28.0 0.8 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Gryzun PF07919.7 KPI36621.1 - 2.5e-78 263.7 0.0 1e-67 228.7 0.3 2.1 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 KPI36621.1 - 1.7e-45 155.4 0.1 3.7e-45 154.3 0.1 1.5 1 1 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.2 KPI36621.1 - 0.082 12.7 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Cas1_AcylT PF07779.7 KPI36622.1 - 3.8e-95 319.1 29.3 4.5e-95 318.9 18.5 1.9 1 1 1 2 2 2 1 10 TM Acyl Transferase domain found in Cas1p MFS_1 PF07690.11 KPI36622.1 - 6.2e-23 81.0 43.0 6.2e-23 81.0 29.8 3.0 3 1 0 3 3 3 1 Major Facilitator Superfamily PC-Esterase PF13839.1 KPI36622.1 - 4.5e-11 43.0 0.0 6.8e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Lipase_GDSL_2 PF13472.1 KPI36622.1 - 0.0031 17.6 0.0 0.0071 16.5 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MARVEL PF01284.18 KPI36623.1 - 0.00034 20.4 10.7 0.0009 19.0 7.4 1.5 1 1 0 1 1 1 1 Membrane-associating domain VIT1 PF01988.14 KPI36623.1 - 0.079 12.4 0.7 0.1 12.0 0.5 1.3 1 0 0 1 1 1 0 VIT family FA_hydroxylase PF04116.8 KPI36623.1 - 0.25 11.7 5.1 4.1 7.8 0.1 2.3 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily zf-MYND PF01753.13 KPI36624.1 - 3.1e-09 36.5 12.6 6e-09 35.6 8.7 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KPI36624.1 - 0.39 10.3 10.2 0.79 9.4 7.0 1.5 1 0 0 1 1 1 0 HIT zinc finger UFD1 PF03152.9 KPI36625.1 - 4.2e-65 218.1 0.0 5.2e-65 217.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_N PF02359.13 KPI36625.1 - 0.15 12.0 0.0 0.61 10.0 0.0 1.9 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain Pex16 PF08610.5 KPI36626.1 - 1.2e-73 248.0 0.1 6.9e-70 235.6 0.1 2.1 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Methyltransf_11 PF08241.7 KPI36627.1 - 8.3e-12 45.4 0.1 2e-11 44.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI36627.1 - 2.6e-08 33.5 0.0 3.8e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI36627.1 - 3.7e-08 33.7 0.2 9.2e-08 32.4 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI36627.1 - 7.9e-08 32.5 0.0 1.5e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI36627.1 - 1.3e-06 28.9 0.0 2.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI36627.1 - 2.9e-06 27.0 0.0 1.3e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 KPI36627.1 - 0.0053 16.1 0.1 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 KPI36627.1 - 0.0061 15.2 0.0 0.0089 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 KPI36627.1 - 0.0066 16.4 0.1 0.019 14.9 0.1 1.8 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 KPI36627.1 - 0.029 13.4 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF445 PF04286.7 KPI36629.1 - 0.00012 21.7 2.8 0.00024 20.7 2.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Abhydrolase_6 PF12697.2 KPI36630.1 - 3.3e-13 50.0 3.6 3.7e-13 49.9 1.6 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI36630.1 - 5.8e-08 32.6 0.1 1.2e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KPI36630.1 - 0.0033 17.0 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 KPI36630.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.15 KPI36630.1 - 0.055 13.0 0.0 0.18 11.3 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Fungal_trans PF04082.13 KPI36631.1 - 2.9e-13 49.3 0.9 4.6e-13 48.6 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Serglycin PF04360.7 KPI36631.1 - 0.023 14.4 0.3 0.13 11.9 0.2 2.0 2 1 0 2 2 2 0 Serglycin Peptidase_S58 PF03576.9 KPI36632.1 - 3.5e-91 305.7 0.0 6.2e-91 304.9 0.0 1.4 1 1 0 1 1 1 1 Peptidase family S58 Rpp20 PF12328.3 KPI36633.1 - 3.5e-39 133.7 14.3 1.1e-38 132.1 9.9 1.7 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KPI36633.1 - 1.3e-20 72.7 1.3 2.2e-20 72.0 0.9 1.4 1 0 0 1 1 1 1 Alba TATR PF03430.8 KPI36633.1 - 0.39 9.2 4.4 0.48 9.0 3.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator ADH_N PF08240.7 KPI36636.1 - 1.4e-06 28.0 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI36636.1 - 4.6e-06 26.2 0.0 8.2e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPR_MLP1_2 PF07926.7 KPI36637.1 - 0.0022 17.7 4.7 0.0022 17.7 3.3 3.3 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein DUF2205 PF10224.4 KPI36637.1 - 0.035 13.6 2.5 0.083 12.4 0.7 2.4 1 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF1351 PF07083.6 KPI36637.1 - 0.075 12.6 7.1 0.038 13.6 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) YukC PF10140.4 KPI36637.1 - 0.26 9.8 6.1 0.048 12.2 1.0 2.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC DUF4200 PF13863.1 KPI36637.1 - 0.83 9.6 22.0 0.016 15.1 9.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) NPV_P10 PF05531.7 KPI36637.1 - 2.5 8.4 5.0 13 6.1 0.6 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 KPI36637.1 - 5.1 4.8 13.2 1.1 7.0 6.3 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 KPI36638.1 - 0.095 12.5 0.7 0.2 11.4 0.5 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 KPI36638.1 - 0.28 11.0 0.1 0.28 11.0 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) p450 PF00067.17 KPI36639.1 - 1.2e-61 208.6 0.0 1.6e-61 208.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EthD PF07110.6 KPI36641.1 - 1.5e-12 48.3 0.0 1.9e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 EthD domain adh_short_C2 PF13561.1 KPI36642.1 - 4e-31 108.6 2.7 4.6e-31 108.4 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI36642.1 - 7.3e-28 97.5 6.3 9.9e-28 97.1 4.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI36642.1 - 5.9e-12 45.6 4.8 8.2e-12 45.1 3.3 1.2 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KPI36642.1 - 2.6e-05 23.3 0.2 5.8e-05 22.2 0.2 1.5 1 1 1 2 2 2 1 Saccharopine dehydrogenase 3HCDH_N PF02737.13 KPI36642.1 - 0.00023 20.8 1.4 0.0003 20.5 0.3 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 KPI36642.1 - 0.0022 17.8 0.5 0.0066 16.2 0.3 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KPI36642.1 - 0.0049 15.8 0.0 0.0077 15.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KPI36642.1 - 0.0098 15.3 0.9 0.017 14.5 0.4 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI36642.1 - 0.015 14.0 0.9 0.043 12.5 0.6 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ThiF PF00899.16 KPI36642.1 - 0.018 14.8 0.5 0.039 13.7 0.3 1.6 1 1 0 1 1 1 0 ThiF family Methyltransf_12 PF08242.7 KPI36642.1 - 0.042 14.3 0.3 0.12 12.8 0.2 1.7 1 1 0 1 1 1 0 Methyltransferase domain NAD_binding_10 PF13460.1 KPI36642.1 - 0.3 11.0 3.5 0.78 9.7 2.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding Acetyltransf_6 PF13480.1 KPI36643.1 - 0.0038 17.2 0.3 0.0064 16.4 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GPI PF06560.6 KPI36643.1 - 0.13 11.3 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Myb_DNA-binding PF00249.26 KPI36644.1 - 2.8e-11 43.2 1.6 8.4e-09 35.3 0.0 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KPI36644.1 - 2e-09 37.3 0.3 1.3e-05 25.1 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain COesterase PF00135.23 KPI36645.1 - 3.4e-52 177.8 0.0 4.6e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family MFS_1 PF07690.11 KPI36646.1 - 5.3e-25 87.8 22.3 2.6e-24 85.6 15.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily LtrA PF06772.6 KPI36647.1 - 3.3e-11 42.7 25.3 1.2e-10 40.8 17.5 1.9 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) APH PF01636.18 KPI36648.1 - 9.1e-18 64.8 0.9 3.1e-17 63.1 0.6 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family MitoNEET_N PF10660.4 KPI36648.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus ABM PF03992.11 KPI36649.1 - 1.2e-06 28.4 0.1 1.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Mak10 PF04112.8 KPI36650.1 - 4.5e-49 165.9 0.0 9.4e-49 164.8 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase FAD_binding_2 PF00890.19 KPI36651.1 - 1.1e-79 268.2 0.1 1.4e-79 267.9 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KPI36651.1 - 1.2e-10 41.0 0.1 2.8e-08 33.2 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.19 KPI36651.1 - 5.9e-10 38.5 0.7 1.1e-08 34.4 0.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KPI36651.1 - 2.9e-05 23.2 0.4 0.00017 20.7 0.2 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 KPI36651.1 - 4.1e-05 23.5 0.3 0.00012 22.0 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI36651.1 - 0.00014 21.8 0.1 0.00057 19.8 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI36651.1 - 0.00024 19.7 0.9 0.00037 19.0 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KPI36651.1 - 0.0011 17.9 0.6 0.0074 15.1 0.6 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KPI36651.1 - 0.05 13.6 0.1 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 KPI36651.1 - 0.08 11.2 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor Chs3p PF12271.3 KPI36652.1 - 1.8e-100 335.7 4.1 2e-100 335.5 2.9 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Fijivirus_P9-2 PF06837.6 KPI36652.1 - 3.4 6.7 6.7 5.7 5.9 4.6 1.4 1 0 0 1 1 1 0 Fijivirus P9-2 protein DUF202 PF02656.10 KPI36653.1 - 4.3e-08 33.2 4.6 4.3e-08 33.2 3.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3987 PF13148.1 KPI36653.1 - 2.1 6.8 9.3 3.2 6.2 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) NARP1 PF12569.3 KPI36653.1 - 5.6 5.6 10.4 7.9 5.1 7.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 VID27 PF08553.5 KPI36653.1 - 7.9 4.5 7.8 11 4.0 5.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Sec10 PF07393.6 KPI36655.1 - 1.2e-175 585.6 0.0 3.7e-174 580.7 0.0 2.1 1 1 0 1 1 1 1 Exocyst complex component Sec10 GAS PF13851.1 KPI36655.1 - 0.013 14.7 0.9 0.026 13.7 0.6 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fungal_trans PF04082.13 KPI36656.1 - 1e-05 24.5 0.1 2.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Podoplanin PF05808.6 KPI36657.1 - 0.88 9.1 5.1 1.2 8.7 3.5 1.2 1 0 0 1 1 1 0 Podoplanin Methyltransf_11 PF08241.7 KPI36659.1 - 4.8e-11 43.0 0.0 8.1e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI36659.1 - 4.8e-11 42.4 0.0 7e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI36659.1 - 6.4e-11 42.6 0.1 1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI36659.1 - 1e-10 42.1 0.1 1.6e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI36659.1 - 2.5e-09 37.0 0.0 3.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI36659.1 - 7e-09 35.9 0.0 5.8e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI36659.1 - 5.7e-06 25.6 0.0 7.7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KPI36659.1 - 7.6e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KPI36659.1 - 6.5e-05 22.9 0.1 0.00017 21.6 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.5 KPI36659.1 - 0.00015 20.9 0.0 0.0002 20.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 MTS PF05175.9 KPI36659.1 - 0.00045 19.6 0.3 0.0015 17.9 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.7 KPI36659.1 - 0.0032 16.8 0.0 0.0043 16.3 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase TehB PF03848.9 KPI36659.1 - 0.023 13.8 0.0 0.2 10.8 0.0 2.0 1 1 1 2 2 2 0 Tellurite resistance protein TehB NDUF_B8 PF05821.6 KPI36659.1 - 0.028 14.0 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) ADH_zinc_N PF00107.21 KPI36659.1 - 0.029 13.9 0.0 0.063 12.8 0.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase PCMT PF01135.14 KPI36659.1 - 0.062 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Brix PF04427.13 KPI36660.1 - 4.8e-44 150.3 0.1 5.9e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain ACBP PF00887.14 KPI36661.1 - 3.9e-22 77.7 0.0 6.1e-11 41.8 0.0 2.5 2 0 0 2 2 2 2 Acyl CoA binding protein HTH_9 PF08221.6 KPI36662.1 - 5.2e-10 39.0 3.7 1.6e-06 27.8 0.4 3.3 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 KPI36662.1 - 4.4e-05 22.9 0.1 0.0023 17.4 0.1 3.0 3 0 0 3 3 3 1 TFIIE alpha subunit RNA_pol_Rpc82 PF05645.8 KPI36662.1 - 0.0024 17.4 0.0 0.045 13.2 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 TIP49 PF06068.8 KPI36663.1 - 1.4e-157 524.5 5.5 4e-157 523.0 3.8 1.6 1 1 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KPI36663.1 - 3.7e-07 30.4 0.6 0.0002 21.5 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KPI36663.1 - 2.4e-06 26.7 0.5 0.00076 18.5 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 KPI36663.1 - 1.2e-05 24.3 0.3 2e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 KPI36663.1 - 0.00067 19.6 0.0 0.0053 16.7 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 KPI36663.1 - 0.00095 18.3 0.6 0.013 14.6 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 KPI36663.1 - 0.0011 19.1 0.0 0.26 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KPI36663.1 - 0.015 15.0 0.1 1.2 8.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KPI36663.1 - 0.043 13.2 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_32 PF13654.1 KPI36663.1 - 0.05 12.2 0.0 0.085 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KPI36663.1 - 0.075 12.7 0.9 0.22 11.3 0.6 1.8 1 1 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 KPI36663.1 - 0.1 11.9 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain PEMT PF04191.8 KPI36664.1 - 1.6e-26 92.4 2.2 2.6e-26 91.7 1.5 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF4131 PF13567.1 KPI36664.1 - 0.21 10.9 2.2 0.81 9.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Acetyltransf_1 PF00583.19 KPI36665.1 - 8.5e-09 35.3 0.0 2.7e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI36665.1 - 0.0018 18.3 0.1 0.0058 16.7 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI36665.1 - 0.0023 18.0 0.0 0.0062 16.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KPI36665.1 - 0.057 13.1 0.0 7.9 6.3 0.0 2.5 2 0 0 2 2 2 0 FR47-like protein PBP1_TM PF14812.1 KPI36665.1 - 0.26 11.6 3.4 0.46 10.8 2.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal 2-oxoacid_dh PF00198.18 KPI36666.1 - 3.6e-61 206.3 0.6 1.8e-34 119.0 0.1 2.2 1 1 1 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KPI36666.1 - 3.2e-18 65.1 0.9 3.2e-18 65.1 0.6 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 KPI36666.1 - 1.3e-13 50.3 0.0 2.8e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Dor1 PF04124.7 KPI36667.1 - 0.00031 19.3 1.5 0.001 17.5 1.0 1.9 1 0 0 1 1 1 1 Dor1-like family DUF2130 PF09903.4 KPI36667.1 - 0.00053 18.8 2.9 0.025 13.3 0.4 2.6 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2130) Lectin_N PF03954.9 KPI36667.1 - 0.17 11.2 9.7 0.56 9.5 0.4 4.4 4 1 0 4 4 4 0 Hepatic lectin, N-terminal domain DUF310 PF03750.8 KPI36667.1 - 0.2 11.8 1.2 4.3 7.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF310) DUF1664 PF07889.7 KPI36667.1 - 0.3 10.9 10.7 2.5 7.8 0.2 4.4 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) Hemerythrin PF01814.18 KPI36667.1 - 0.96 9.6 4.2 25 5.0 0.1 4.2 4 0 0 4 4 4 0 Hemerythrin HHE cation binding domain DUF948 PF06103.6 KPI36667.1 - 2 8.3 8.5 12 5.8 0.5 3.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) COX17 PF05051.8 KPI36668.1 - 3.9e-19 68.3 7.1 5.2e-19 67.9 4.9 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) AAA PF00004.24 KPI36669.1 - 3.6e-17 62.8 0.0 7.8e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 KPI36669.1 - 1.2e-10 41.3 0.0 3.5e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 BCS1 N terminal AAA_17 PF13207.1 KPI36669.1 - 1.5e-05 25.8 0.0 4.1e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KPI36669.1 - 0.00011 21.2 0.0 0.00021 20.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KPI36669.1 - 0.00016 21.3 0.0 0.00043 19.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KPI36669.1 - 0.00054 19.6 0.0 0.0051 16.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KPI36669.1 - 0.00078 18.8 0.0 0.0017 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KPI36669.1 - 0.001 19.0 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KPI36669.1 - 0.0022 17.8 0.0 0.0047 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KPI36669.1 - 0.0031 17.4 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain Parvo_NS1 PF01057.12 KPI36669.1 - 0.0038 16.1 0.0 0.041 12.7 0.0 2.1 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 KPI36669.1 - 0.0039 16.7 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KPI36669.1 - 0.0052 16.2 0.0 0.0098 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 KPI36669.1 - 0.009 16.1 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KPI36669.1 - 0.0094 14.7 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 KPI36669.1 - 0.016 15.5 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KPI36669.1 - 0.03 13.5 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 KPI36669.1 - 0.03 14.1 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 KPI36669.1 - 0.035 14.2 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase KaiC PF06745.8 KPI36669.1 - 0.062 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.22 KPI36669.1 - 0.11 12.8 0.0 0.6 10.3 0.0 2.2 3 0 0 3 3 2 0 ABC transporter Polyoma_lg_T_C PF06431.6 KPI36669.1 - 0.12 11.0 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus NACHT PF05729.7 KPI36669.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Ring_hydroxyl_A PF00848.14 KPI36670.1 - 5e-35 121.0 0.1 1.2e-34 119.7 0.0 1.7 2 0 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 KPI36670.1 - 1e-17 63.5 0.0 1.9e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain adh_short_C2 PF13561.1 KPI36671.1 - 1.2e-23 84.1 0.0 1.7e-23 83.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI36671.1 - 4.1e-23 82.1 0.2 5.2e-23 81.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI36671.1 - 4.6e-08 32.9 0.2 1e-07 31.8 0.2 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI36671.1 - 0.00023 20.6 0.2 0.046 13.1 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 KPI36671.1 - 0.0041 16.3 0.0 0.0061 15.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 KPI36671.1 - 0.094 12.5 0.2 1.1 9.0 0.1 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.12 KPI36671.1 - 0.099 13.0 0.2 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AA_permease PF00324.16 KPI36672.1 - 2e-115 385.8 42.2 2.5e-115 385.5 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI36672.1 - 2.6e-36 125.0 44.2 3.2e-36 124.8 30.7 1.1 1 0 0 1 1 1 1 Amino acid permease CDC14 PF08045.6 KPI36673.1 - 1.3e-64 217.8 0.5 1.6e-64 217.5 0.3 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component DUF2390 PF09523.5 KPI36673.1 - 0.069 13.3 0.6 3.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) HAD_2 PF13419.1 KPI36674.1 - 2.5e-20 73.3 0.0 3.6e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KPI36674.1 - 9e-05 22.9 0.0 0.00017 22.0 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2922 PF11148.3 KPI36674.1 - 0.011 15.3 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) UPF1_Zn_bind PF09416.5 KPI36675.1 - 1.2e-70 236.0 3.7 1.2e-70 236.0 2.6 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KPI36675.1 - 1.2e-59 201.1 0.0 2.4e-59 200.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KPI36675.1 - 4.4e-58 196.6 1.8 7.2e-58 195.9 1.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KPI36675.1 - 1.6e-14 53.4 0.1 4.3e-14 52.0 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KPI36675.1 - 6.1e-12 45.5 0.2 1.2e-10 41.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KPI36675.1 - 1.2e-08 35.0 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KPI36675.1 - 3.2e-05 23.5 0.1 0.32 10.4 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 KPI36675.1 - 0.00018 21.2 0.0 0.00045 19.9 0.0 1.7 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 KPI36675.1 - 0.00025 20.4 0.1 0.003 16.8 0.0 2.3 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 KPI36675.1 - 0.0017 17.4 0.7 0.009 15.0 0.1 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 KPI36675.1 - 0.0044 16.0 0.0 0.53 9.1 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase DEAD PF00270.24 KPI36675.1 - 0.0081 15.6 0.1 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_S13_N PF08069.7 KPI36675.1 - 0.011 15.5 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain KaiC PF06745.8 KPI36675.1 - 0.033 13.2 0.0 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.1 KPI36675.1 - 0.041 13.2 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KPI36675.1 - 0.077 13.1 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KPI36675.1 - 0.086 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KPI36675.1 - 0.1 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 KPI36675.1 - 0.15 11.3 0.0 0.37 9.9 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein zf-RanBP PF00641.13 KPI36675.1 - 3 7.0 7.0 0.38 9.9 1.4 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others UQ_con PF00179.21 KPI36676.1 - 1.4e-17 63.4 0.0 1.5e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KPI36676.1 - 0.011 15.6 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain Abhydrolase_5 PF12695.2 KPI36677.1 - 7.8e-12 45.1 0.0 3.2e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KPI36677.1 - 8.4e-08 31.0 0.0 2.7e-05 22.8 0.0 2.4 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 KPI36677.1 - 7.5e-07 28.5 0.0 1.2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KPI36677.1 - 8.9e-07 29.0 0.1 3.1e-06 27.2 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KPI36677.1 - 3.5e-06 26.6 0.3 7.8e-06 25.5 0.2 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 KPI36677.1 - 0.049 13.3 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 KPI36677.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DLH PF01738.13 KPI36677.1 - 0.075 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Zn_clus PF00172.13 KPI36678.1 - 7.7e-07 28.9 8.8 1.4e-06 28.1 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brix PF04427.13 KPI36679.1 - 2.7e-28 98.9 0.0 3.5e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Brix domain Scramblase PF03803.10 KPI36680.1 - 2.2e-49 167.5 0.0 1.8e-47 161.2 0.0 2.8 1 1 0 1 1 1 1 Scramblase zf-H2C2_2 PF13465.1 KPI36681.1 - 1.6 9.1 5.2 0.37 11.1 0.2 2.5 3 0 0 3 3 3 0 Zinc-finger double domain TRAPPC10 PF12584.3 KPI36682.1 - 3e-15 56.0 0.0 1.2e-14 54.0 0.0 2.0 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 p450 PF00067.17 KPI36683.1 - 2.9e-53 181.0 0.0 4.6e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Myb_DNA-bind_6 PF13921.1 KPI36684.1 - 0.011 15.8 0.1 0.18 11.9 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain MAGE_N PF12440.3 KPI36684.1 - 7.1 6.9 10.8 0.41 10.9 2.5 2.4 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal ABC_tran PF00005.22 KPI36685.1 - 2.4e-27 95.9 0.0 3.9e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 KPI36685.1 - 2.2e-15 56.5 24.2 3.1e-15 56.0 16.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 KPI36685.1 - 8.3e-10 39.0 0.0 0.00027 20.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KPI36685.1 - 0.00074 18.9 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KPI36685.1 - 0.0016 18.7 0.0 0.0034 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KPI36685.1 - 0.013 14.6 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KPI36685.1 - 0.025 14.5 0.1 0.062 13.2 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.14 KPI36685.1 - 0.056 12.6 0.1 0.29 10.3 0.1 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 KPI36685.1 - 0.083 11.9 0.1 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.1 KPI36685.1 - 0.22 10.5 0.0 12 4.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain EthD PF07110.6 KPI36686.1 - 5.9e-06 27.1 1.5 1.6e-05 25.7 1.0 1.6 1 1 0 1 1 1 1 EthD domain GYF PF02213.11 KPI36687.1 - 3.5e-10 39.3 0.3 7e-10 38.3 0.2 1.5 1 0 0 1 1 1 1 GYF domain Ribosomal_60s PF00428.14 KPI36688.1 - 0.03 14.7 2.1 0.049 14.0 1.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein MFS_1 PF07690.11 KPI36689.1 - 1e-25 90.2 53.4 8.8e-25 87.1 32.3 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KPI36689.1 - 1.2e-25 89.7 25.0 1.7e-25 89.3 17.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3149 PF11346.3 KPI36689.1 - 0.011 15.2 1.1 1.2 8.7 0.1 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) G_glu_transpept PF01019.16 KPI36690.1 - 4.2e-126 421.4 0.0 2.1e-117 392.7 0.0 2.2 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase WD40 PF00400.27 KPI36692.1 - 5e-24 83.2 6.4 3.6e-07 29.8 0.0 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 KPI36692.1 - 5.9e-06 24.7 0.4 0.0026 15.9 0.0 2.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 TPR_11 PF13414.1 KPI36696.1 - 2.4e-10 39.9 1.4 0.0036 16.9 0.0 5.1 4 1 0 5 5 5 2 TPR repeat TPR_16 PF13432.1 KPI36696.1 - 8e-09 35.9 0.5 0.034 14.8 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KPI36696.1 - 1.1e-08 34.8 9.5 0.019 14.8 0.1 5.8 3 2 5 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 KPI36696.1 - 1.5e-08 33.9 6.4 0.0046 16.7 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 KPI36696.1 - 4.2e-08 33.1 14.9 0.026 15.1 0.0 5.9 5 2 1 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KPI36696.1 - 4e-07 29.3 0.1 0.17 11.5 0.0 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 KPI36696.1 - 4.7e-07 29.1 6.2 0.048 13.4 0.1 5.4 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KPI36696.1 - 5.9e-07 29.7 12.6 0.22 11.8 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 KPI36696.1 - 1.4e-05 24.8 5.5 0.19 11.7 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KPI36696.1 - 2.5e-05 23.7 0.0 0.051 13.3 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 KPI36696.1 - 0.0004 20.5 11.5 0.99 10.0 0.4 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KPI36696.1 - 0.003 17.6 0.0 4.7 7.4 0.0 3.6 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 HrpB7 PF09486.5 KPI36696.1 - 0.0096 15.8 1.7 0.0096 15.8 1.2 2.1 2 1 0 2 2 2 1 Bacterial type III secretion protein (HrpB7) TPR_6 PF13174.1 KPI36696.1 - 0.09 13.2 5.7 4.5 7.9 0.0 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat RVT_1 PF00078.22 KPI36697.1 - 3.6e-09 36.2 0.0 7e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fungal_trans PF04082.13 KPI36698.1 - 6.3e-22 77.6 0.0 1e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI36698.1 - 1.8e-06 27.7 10.1 3.2e-06 26.9 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RdRP PF05183.7 KPI36699.1 - 2.2e-99 333.7 0.0 3.3e-99 333.1 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase ATP-synt_Eps PF04627.8 KPI36700.1 - 7.6e-22 76.6 0.7 1.1e-21 76.1 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain adh_short_C2 PF13561.1 KPI36701.1 - 7.5e-30 104.4 1.4 9.2e-30 104.1 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI36701.1 - 8.6e-22 77.8 0.9 1.1e-21 77.4 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KPI36701.1 - 4.1e-08 33.1 0.4 6.3e-08 32.4 0.3 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI36701.1 - 0.00027 21.0 0.1 0.018 15.0 0.0 2.3 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KPI36701.1 - 0.0071 16.1 0.1 0.025 14.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KPI36701.1 - 0.055 12.9 0.1 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family F_actin_cap_B PF01115.12 KPI36702.1 - 3e-81 272.1 0.0 4.2e-81 271.7 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit AAA PF00004.24 KPI36703.1 - 3e-16 59.8 0.2 8e-16 58.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 KPI36703.1 - 1.7e-15 56.7 0.0 1.6e-14 53.6 0.0 2.3 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KPI36703.1 - 3.2e-14 52.9 0.0 7.5e-14 51.7 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KPI36703.1 - 1.4e-11 43.8 0.0 2.7e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KPI36703.1 - 2.6e-07 30.8 0.2 7.1e-06 26.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KPI36703.1 - 9.6e-07 28.5 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KPI36703.1 - 9.7e-07 28.9 0.1 0.00016 21.7 0.0 3.1 2 2 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 KPI36703.1 - 1.5e-06 27.1 0.0 0.012 14.4 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 KPI36703.1 - 2e-06 27.4 0.0 6.3e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KPI36703.1 - 2.1e-06 26.9 0.1 3.9e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 KPI36703.1 - 2.9e-06 26.9 0.0 7.3e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit DUF815 PF05673.8 KPI36703.1 - 1e-05 24.5 0.0 2.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 KPI36703.1 - 2.3e-05 24.1 0.1 6.1e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KPI36703.1 - 0.00012 21.8 0.5 0.00036 20.2 0.1 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KPI36703.1 - 0.00015 21.6 0.0 0.00038 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KPI36703.1 - 0.00044 19.8 0.0 0.00089 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KPI36703.1 - 0.00055 19.5 0.1 0.0021 17.6 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KPI36703.1 - 0.00099 18.3 0.0 0.24 10.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_10 PF12846.2 KPI36703.1 - 0.0021 17.5 0.1 1.3 8.4 0.0 2.5 1 1 1 2 2 2 2 AAA-like domain DEAD PF00270.24 KPI36703.1 - 0.003 17.0 0.0 0.073 12.5 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 KPI36703.1 - 0.0046 16.3 0.1 0.019 14.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KPI36703.1 - 0.0076 16.2 0.0 0.015 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KPI36703.1 - 0.0099 15.3 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 KPI36703.1 - 0.013 15.0 0.0 0.049 13.1 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.4 KPI36703.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KPI36703.1 - 0.031 14.1 0.0 0.5 10.1 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 KPI36703.1 - 0.037 14.8 0.0 0.079 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KPI36703.1 - 0.043 12.9 0.1 0.14 11.2 0.1 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 KPI36703.1 - 0.049 13.3 0.0 0.095 12.3 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase SNF2_N PF00176.18 KPI36703.1 - 0.065 12.0 0.0 3.7 6.2 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain RNA_helicase PF00910.17 KPI36703.1 - 0.07 13.3 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KPI36703.1 - 0.09 12.4 0.3 1.2 8.7 0.0 2.4 2 1 0 2 2 1 0 NACHT domain AAA_18 PF13238.1 KPI36703.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain TAFII28 PF04719.9 KPI36703.1 - 0.11 12.2 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 hTAFII28-like protein conserved region ABC_tran PF00005.22 KPI36704.1 - 4.5e-19 69.1 0.6 8.4e-19 68.2 0.4 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KPI36704.1 - 1.8e-11 44.5 2.2 9.5e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 KPI36704.1 - 2.1e-07 30.2 19.5 3.5e-07 29.6 9.9 2.6 2 1 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.14 KPI36704.1 - 3.1e-07 29.8 0.4 3.9e-05 22.9 0.3 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KPI36704.1 - 8.8e-05 21.9 0.5 0.00023 20.6 0.4 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KPI36704.1 - 0.03 14.6 1.0 0.05 13.9 0.2 1.7 2 0 0 2 2 2 0 AAA domain TyeA PF09059.5 KPI36704.1 - 0.06 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 TyeA MutS_V PF00488.16 KPI36704.1 - 0.061 12.7 0.0 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 MutS domain V AAA_16 PF13191.1 KPI36704.1 - 0.088 12.7 0.1 0.29 11.1 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain CENP-F_N PF10481.4 KPI36704.1 - 0.16 11.3 0.5 0.25 10.7 0.3 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain AAA_15 PF13175.1 KPI36704.1 - 0.26 10.2 0.0 0.41 9.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.27 KPI36705.1 - 1.8e-36 122.7 6.0 3.9e-07 29.7 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KPI36705.1 - 8e-29 99.3 0.1 1.8e-28 98.2 0.1 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex FA_desaturase PF00487.19 KPI36706.1 - 1.1e-26 93.7 18.1 1.6e-26 93.2 12.6 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KPI36706.1 - 3e-05 24.0 0.0 9.8e-05 22.3 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3474) Peptidase_M16 PF00675.15 KPI36707.1 - 3.7e-17 62.4 0.0 8.5e-17 61.2 0.0 1.7 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KPI36707.1 - 6.4e-12 45.5 0.0 1.2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain HET PF06985.6 KPI36708.1 - 2e-32 112.2 0.9 3.8e-32 111.3 0.6 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LSM14 PF12701.2 KPI36709.1 - 3e-27 94.2 0.0 5.9e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 KPI36709.1 - 5.2e-16 59.0 6.0 5.2e-16 59.0 4.1 2.1 3 0 0 3 3 3 1 FDF domain SM-ATX PF14438.1 KPI36709.1 - 0.082 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Ataxin 2 SM domain GRP PF07172.6 KPI36709.1 - 0.5 10.8 22.0 0.91 10.0 12.7 2.4 2 0 0 2 2 2 0 Glycine rich protein family MAPEG PF01124.13 KPI36710.1 - 3.8e-08 33.0 0.8 7.1e-08 32.1 0.6 1.4 1 0 0 1 1 1 1 MAPEG family DUF883 PF05957.8 KPI36710.1 - 0.027 14.8 0.8 0.055 13.8 0.5 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF4188 PF13826.1 KPI36711.1 - 5.1e-26 91.0 0.2 7.3e-26 90.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 KPI36711.1 - 7.8e-05 21.8 0.2 0.00011 21.4 0.2 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase Pro_isomerase PF00160.16 KPI36713.1 - 1e-31 110.2 0.0 1.9e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ABC2_membrane PF01061.19 KPI36714.1 - 5.9e-65 218.3 51.6 1.5e-43 148.4 11.6 3.6 4 0 0 4 4 3 3 ABC-2 type transporter ABC_tran PF00005.22 KPI36714.1 - 1.3e-35 122.6 0.0 1e-17 64.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KPI36714.1 - 2.7e-32 110.5 0.4 5.2e-27 93.5 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KPI36714.1 - 1.2e-06 28.4 0.1 5.2e-06 26.4 0.0 2.3 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KPI36714.1 - 7.9e-06 25.4 0.1 0.0017 17.7 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KPI36714.1 - 1.2e-05 25.4 0.0 0.079 12.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KPI36714.1 - 0.00016 21.7 0.2 0.027 14.4 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KPI36714.1 - 0.00022 20.6 0.4 0.005 16.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KPI36714.1 - 0.00039 21.2 0.0 0.13 13.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KPI36714.1 - 0.00089 18.7 0.1 0.012 15.0 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KPI36714.1 - 0.001 19.1 0.1 0.31 11.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KPI36714.1 - 0.0012 18.5 0.8 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 KPI36714.1 - 0.0018 18.1 0.1 0.062 13.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KPI36714.1 - 0.002 17.3 0.1 0.0053 15.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 KPI36714.1 - 0.0032 17.0 0.8 0.88 9.2 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 KPI36714.1 - 0.0079 16.1 0.3 0.035 14.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KPI36714.1 - 0.016 15.5 0.0 0.32 11.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KPI36714.1 - 0.018 14.2 0.0 16 4.6 0.0 3.4 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 KPI36714.1 - 0.03 14.0 0.0 2.7 7.6 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase ABC2_membrane_3 PF12698.2 KPI36714.1 - 0.041 12.9 33.3 0.26 10.3 10.1 2.6 2 0 0 2 2 2 0 ABC-2 family transporter protein Miro PF08477.8 KPI36714.1 - 0.041 14.3 0.1 5.5 7.5 0.0 3.0 3 0 0 3 3 2 0 Miro-like protein NACHT PF05729.7 KPI36714.1 - 0.051 13.2 0.4 4.9 6.7 0.2 2.4 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 KPI36714.1 - 0.051 13.9 2.7 0.4 10.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 KPI36714.1 - 0.068 12.6 0.1 3.3 7.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 KPI36714.1 - 0.15 11.5 0.3 2.4 7.6 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation EthD PF07110.6 KPI36715.1 - 7e-12 46.1 0.0 9.5e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 EthD domain AsnC_trans_reg PF01037.16 KPI36715.1 - 0.064 12.9 0.0 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 AsnC family Helicase_C PF00271.26 KPI36716.1 - 1.4e-20 72.9 0.3 4.3e-20 71.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KPI36716.1 - 1.8e-20 73.1 0.0 1.4e-19 70.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KPI36716.1 - 5.9e-19 68.6 0.0 1.2e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Arch_flagellin PF01917.11 KPI36716.1 - 0.023 14.3 0.1 1.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Archaebacterial flagellin DUF2075 PF09848.4 KPI36716.1 - 0.039 12.9 0.0 0.087 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 KPI36716.1 - 0.044 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KPI36716.1 - 0.088 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NmrA PF05368.8 KPI36717.1 - 6.5e-22 77.9 0.2 8.3e-22 77.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI36717.1 - 1.3e-13 51.3 0.2 1.3e-13 51.3 0.1 1.8 2 1 1 3 3 3 1 NADH(P)-binding Epimerase PF01370.16 KPI36717.1 - 2.3e-05 23.9 0.2 0.062 12.7 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KPI36717.1 - 0.0001 22.6 0.4 0.00032 21.0 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain CW_binding_2 PF04122.7 KPI36717.1 - 0.17 12.1 2.7 1.2 9.3 0.1 3.0 2 1 1 3 3 3 0 Putative cell wall binding repeat 2 PAGK PF15284.1 KPI36718.1 - 0.041 13.6 2.9 0.056 13.1 0.0 2.4 2 0 0 2 2 2 0 Phage-encoded virulence factor DUF4389 PF14333.1 KPI36718.1 - 1.2 8.9 7.0 0.22 11.2 1.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) SET PF00856.23 KPI36720.1 - 9.1e-14 52.0 0.0 3.1e-13 50.3 0.0 1.9 1 1 0 1 1 1 1 SET domain Metallophos PF00149.23 KPI36721.1 - 7.6e-41 139.7 0.9 1.1e-40 139.1 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ASXH PF13919.1 KPI36722.1 - 5.2e-14 52.2 0.0 7.1e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Asx homology domain DUF4661 PF15576.1 KPI36724.1 - 0.045 13.3 0.3 0.065 12.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) YqfQ PF14181.1 KPI36724.1 - 1.6 8.7 5.2 2.6 8.0 0.0 2.1 1 1 1 2 2 2 0 YqfQ-like protein MFS_1 PF07690.11 KPI36725.1 - 2.6e-26 92.2 30.9 2.6e-26 92.2 21.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sec7_N PF12783.2 KPI36726.1 - 2.6e-13 49.7 2.3 7.7e-11 41.7 0.0 4.0 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KPI36726.1 - 0.0019 17.6 0.0 0.03 13.8 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) HEAT PF02985.17 KPI36726.1 - 0.81 9.9 5.3 15 5.9 0.0 5.4 6 0 0 6 6 6 0 HEAT repeat Lin0512_fam PF09585.5 KPI36727.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein (Lin0512_fam) Abhydrolase_3 PF07859.8 KPI36728.1 - 5.4e-35 120.8 0.0 8.5e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI36728.1 - 0.00025 20.3 0.0 0.0009 18.5 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.23 KPI36728.1 - 0.00028 19.7 0.2 0.00064 18.5 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KPI36728.1 - 0.038 13.7 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.13 KPI36728.1 - 0.11 11.7 0.0 0.48 9.6 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family Conotoxin PF02950.12 KPI36729.1 - 0.024 15.4 3.4 0.024 15.4 2.3 1.8 2 0 0 2 2 2 0 Conotoxin Dispanin PF04505.7 KPI36729.1 - 8 6.0 7.8 0.34 10.4 0.2 2.2 2 0 0 2 2 2 0 Interferon-induced transmembrane protein AAA_33 PF13671.1 KPI36730.1 - 2.6e-14 53.3 0.0 3.7e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 KPI36730.1 - 9.7e-14 51.5 0.0 1.2e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 KPI36730.1 - 4.5e-11 43.6 0.0 7.3e-11 42.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KPI36730.1 - 3.9e-10 40.1 0.0 8.8e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 KPI36730.1 - 1.4e-05 24.0 0.0 2.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 KPI36730.1 - 0.00017 21.8 0.4 0.00046 20.3 0.3 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KPI36730.1 - 0.00019 21.1 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_28 PF13521.1 KPI36730.1 - 0.00046 20.1 0.0 0.0009 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KPI36730.1 - 0.00049 20.0 0.0 0.0051 16.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 KPI36730.1 - 0.0016 18.6 0.1 0.0044 17.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 KPI36730.1 - 0.0022 17.6 0.0 0.0083 15.7 0.0 1.9 1 1 1 2 2 2 1 NACHT domain RNA_helicase PF00910.17 KPI36730.1 - 0.0024 18.0 0.1 0.0082 16.2 0.0 1.7 1 1 0 2 2 1 1 RNA helicase Cytidylate_kin2 PF13189.1 KPI36730.1 - 0.0024 17.7 0.1 0.0094 15.8 0.1 2.0 1 1 0 1 1 1 1 Cytidylate kinase-like family ABC_tran PF00005.22 KPI36730.1 - 0.0061 16.8 0.1 0.012 15.8 0.0 1.8 1 1 0 1 1 1 1 ABC transporter CoaE PF01121.15 KPI36730.1 - 0.0073 15.7 0.0 0.018 14.4 0.0 1.6 2 0 0 2 2 2 1 Dephospho-CoA kinase AAA_19 PF13245.1 KPI36730.1 - 0.0074 16.0 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain tRNA_lig_kinase PF08303.6 KPI36730.1 - 0.0081 16.0 0.0 0.016 15.1 0.0 1.5 1 1 0 1 1 1 1 tRNA ligase kinase domain Viral_helicase1 PF01443.13 KPI36730.1 - 0.013 15.0 0.1 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IPPT PF01715.12 KPI36730.1 - 0.016 14.2 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 IPP transferase AAA_16 PF13191.1 KPI36730.1 - 0.025 14.5 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain IPT PF01745.11 KPI36730.1 - 0.026 13.6 0.0 0.057 12.5 0.0 1.5 2 0 0 2 2 2 0 Isopentenyl transferase Zeta_toxin PF06414.7 KPI36730.1 - 0.026 13.5 0.0 0.061 12.4 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 KPI36730.1 - 0.027 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PRK PF00485.13 KPI36730.1 - 0.031 13.8 0.0 0.071 12.6 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_11 PF13086.1 KPI36730.1 - 0.034 13.6 0.0 0.078 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KPI36730.1 - 0.037 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KPI36730.1 - 0.054 12.9 0.1 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KPI36730.1 - 0.054 12.4 0.0 0.061 12.2 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 KPI36730.1 - 0.054 13.2 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 NTPase PhoH PF02562.11 KPI36730.1 - 0.082 12.1 0.1 0.2 10.8 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 KPI36730.1 - 0.09 12.3 0.2 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain ADK PF00406.17 KPI36730.1 - 0.094 12.5 0.3 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase Arch_ATPase PF01637.13 KPI36730.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase SRP54 PF00448.17 KPI36730.1 - 0.14 11.5 0.4 3.6 6.9 0.0 2.3 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain Claudin_3 PF06653.6 KPI36731.1 - 0.0094 15.6 2.5 0.012 15.3 1.8 1.2 1 0 0 1 1 1 1 Tight junction protein, Claudin-like DUF2269 PF10027.4 KPI36731.1 - 0.023 14.4 1.8 1.6 8.4 0.2 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) Adeno_E3 PF06040.6 KPI36731.1 - 0.13 12.2 1.4 1.2 9.0 0.5 2.2 2 0 0 2 2 2 0 Adenovirus E3 protein FixQ PF05545.6 KPI36731.1 - 0.16 11.6 0.2 0.16 11.6 0.1 1.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF2892 PF11127.3 KPI36731.1 - 4 7.3 5.9 4.7 7.1 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) adh_short PF00106.20 KPI36732.1 - 3.3e-34 118.2 0.4 3.3e-34 118.2 0.2 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI36732.1 - 1e-28 100.7 0.4 1.2e-28 100.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI36732.1 - 1.9e-16 60.2 0.6 6.9e-16 58.4 0.1 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 KPI36732.1 - 1.4e-06 27.9 0.2 3.6e-06 26.5 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI36732.1 - 2.9e-05 24.1 0.7 0.0019 18.2 0.4 2.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KPI36732.1 - 0.00045 19.0 0.0 0.00065 18.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 KPI36732.1 - 0.00056 19.6 0.1 0.0014 18.2 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KPI36732.1 - 0.00066 18.6 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 KPI36732.1 - 0.0012 18.8 0.1 0.0043 17.0 0.0 2.0 3 0 0 3 3 2 1 TrkA-N domain NmrA PF05368.8 KPI36732.1 - 0.011 14.9 0.2 0.11 11.7 0.1 2.0 2 0 0 2 2 2 0 NmrA-like family NAD_Gly3P_dh_N PF01210.18 KPI36732.1 - 0.013 15.2 0.1 0.048 13.3 0.0 1.9 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RmlD_sub_bind PF04321.12 KPI36732.1 - 0.013 14.4 0.1 0.038 12.8 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain Shikimate_DH PF01488.15 KPI36732.1 - 0.031 14.3 0.2 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.18 KPI36732.1 - 0.031 14.0 0.6 0.079 12.7 0.1 1.8 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KPI36732.1 - 0.035 14.5 0.0 0.078 13.4 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.5 KPI36732.1 - 0.05 12.7 0.0 0.11 11.6 0.0 1.6 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) Methyltransf_18 PF12847.2 KPI36732.1 - 0.053 14.1 0.0 0.1 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ELFV_dehydrog PF00208.16 KPI36732.1 - 0.088 12.3 0.3 0.37 10.3 0.1 2.0 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Eno-Rase_NADH_b PF12242.3 KPI36732.1 - 0.17 11.6 1.0 0.34 10.7 0.4 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_4 PF07993.7 KPI36732.1 - 1.9 7.3 4.4 7.2 5.4 0.5 3.1 1 1 2 3 3 3 0 Male sterility protein APC10 PF03256.11 KPI36734.1 - 2.9e-37 128.1 0.0 1.1e-36 126.2 0.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) DUF3613 PF12266.3 KPI36734.1 - 0.14 11.7 1.3 0.33 10.4 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) MFS_1 PF07690.11 KPI36736.1 - 2.1e-40 138.5 34.4 2.9e-40 138.0 23.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI36736.1 - 1.3e-15 56.9 10.6 1.3e-15 56.9 7.3 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KPI36736.1 - 3.3e-05 22.2 2.0 4.7e-05 21.7 1.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NARP1 PF12569.3 KPI36737.1 - 9e-189 628.5 24.7 3.9e-187 623.1 13.7 2.1 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.1 KPI36737.1 - 3e-14 52.2 20.7 0.062 13.9 0.0 11.1 8 3 5 13 13 11 4 Tetratricopeptide repeat TPR_11 PF13414.1 KPI36737.1 - 1.3e-13 50.3 32.0 2.7e-05 23.7 0.1 7.7 7 1 2 10 10 9 3 TPR repeat TPR_2 PF07719.12 KPI36737.1 - 6.7e-11 41.2 25.1 0.0046 16.7 0.0 9.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 KPI36737.1 - 3.7e-10 39.1 8.5 0.12 12.6 0.0 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KPI36737.1 - 4.2e-10 39.8 32.3 0.04 14.2 0.1 7.6 6 3 1 7 7 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 KPI36737.1 - 2.5e-09 37.5 26.7 0.03 14.9 0.0 8.5 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 KPI36737.1 - 2.2e-06 27.0 12.9 0.01 15.5 0.0 7.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 KPI36737.1 - 3.8e-06 26.7 26.2 0.026 14.4 1.9 6.6 5 2 3 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 KPI36737.1 - 0.00021 21.0 8.9 0.039 13.8 0.1 5.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 KPI36737.1 - 0.00026 20.4 29.3 0.00059 19.3 0.1 7.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 KPI36737.1 - 0.0024 17.5 8.6 4.8 7.2 0.0 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_3 PF07720.7 KPI36737.1 - 0.0044 16.7 1.2 3.9 7.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KPI36737.1 - 0.03 14.1 8.4 1.8 8.5 0.0 5.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Patched PF02460.13 KPI36737.1 - 0.24 9.2 0.0 0.38 8.6 0.0 1.2 1 0 0 1 1 1 0 Patched family TPR_6 PF13174.1 KPI36737.1 - 0.25 11.8 25.7 10 6.8 0.1 9.4 11 0 0 11 11 9 0 Tetratricopeptide repeat TPR_10 PF13374.1 KPI36737.1 - 0.26 11.2 7.2 10 6.2 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 KPI36737.1 - 0.3 11.6 0.1 0.3 11.6 0.1 4.7 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF2730 PF10805.3 KPI36737.1 - 0.51 10.0 5.4 42 3.9 0.0 4.0 5 0 0 5 5 4 0 Protein of unknown function (DUF2730) Ada3 PF10198.4 KPI36738.1 - 1.7e-41 141.0 0.2 1.7e-41 141.0 0.2 2.2 2 1 0 2 2 2 1 Histone acetyltransferases subunit 3 SRA1 PF07304.6 KPI36738.1 - 0.04 13.6 0.9 0.33 10.6 0.0 2.6 2 1 0 2 2 2 0 Steroid receptor RNA activator (SRA1) Fungal_trans PF04082.13 KPI36740.1 - 2e-21 76.0 0.4 7.7e-21 74.1 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KPI36741.1 - 8.7e-06 24.7 0.0 1.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HTH_Tnp_Tc5 PF03221.11 KPI36742.1 - 4.5e-10 39.1 0.3 8.6e-10 38.2 0.2 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 KPI36742.1 - 1.2e-05 24.5 1.2 2.9e-05 23.3 0.8 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 KPI36742.1 - 0.00022 20.6 0.4 0.00042 19.8 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.17 KPI36742.1 - 0.00062 19.4 0.2 0.0027 17.3 0.0 2.1 2 0 0 2 2 2 1 MarR family HTH_23 PF13384.1 KPI36742.1 - 0.0068 16.0 0.2 0.021 14.4 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.11 KPI36742.1 - 0.014 14.6 0.2 0.025 13.8 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.1 KPI36742.1 - 0.08 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Tnp_4 PF13613.1 KPI36742.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR_2 PF12802.2 KPI36742.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 MarR family Fungal_trans PF04082.13 KPI36743.1 - 7.4e-09 34.8 0.0 1.6e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3323 PF11796.3 KPI36744.1 - 0.0035 16.7 1.1 0.006 15.9 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminus (DUF3323) NAD_binding_10 PF13460.1 KPI36746.1 - 1.7e-15 57.4 0.1 2.7e-15 56.8 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KPI36746.1 - 8.3e-14 51.4 0.0 1.4e-13 50.6 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 KPI36746.1 - 0.00032 20.9 0.1 0.00083 19.6 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain XdhC_C PF13478.1 KPI36746.1 - 0.00034 20.9 0.1 0.0012 19.1 0.0 1.9 2 0 0 2 2 2 1 XdhC Rossmann domain GFO_IDH_MocA PF01408.17 KPI36746.1 - 0.00036 21.0 0.1 0.00072 20.0 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold THF_DHG_CYH_C PF02882.14 KPI36746.1 - 0.0037 16.3 0.0 0.0064 15.5 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.15 KPI36746.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.10 KPI36746.1 - 0.054 13.3 0.1 0.67 9.7 0.0 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_4 PF07993.7 KPI36746.1 - 0.084 11.7 0.0 0.19 10.6 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein 3Beta_HSD PF01073.14 KPI36746.1 - 0.093 11.4 0.0 0.29 9.7 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KPI36746.1 - 0.093 12.1 0.0 0.2 11.0 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FMN_dh PF01070.13 KPI36747.1 - 7.8e-128 426.2 1.4 9.1e-128 426.0 0.9 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KPI36747.1 - 1.1e-07 31.0 1.8 3.2e-06 26.2 0.6 2.5 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KPI36747.1 - 3.3e-05 23.1 3.9 8e-05 21.9 1.6 2.0 2 0 0 2 2 2 1 Nitronate monooxygenase Glu_synthase PF01645.12 KPI36747.1 - 5.3e-05 22.3 0.5 8e-05 21.7 0.3 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 KPI36747.1 - 0.00013 21.0 0.1 0.0026 16.7 0.0 2.3 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 KPI36747.1 - 0.00048 19.4 0.1 0.0022 17.3 0.0 2.0 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 KPI36747.1 - 0.00072 18.7 2.0 0.068 12.2 0.1 2.4 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG PcrB PF01884.12 KPI36747.1 - 0.035 13.3 1.4 7.5 5.7 0.0 3.2 2 1 1 3 3 3 0 PcrB family HisG_C PF08029.6 KPI36747.1 - 0.096 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 HisG, C-terminal domain Pyr_redox_3 PF13738.1 KPI36748.1 - 1.9e-17 64.0 0.0 4.4e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF3425 PF11905.3 KPI36748.1 - 3.3e-17 62.6 0.1 1.1e-16 60.9 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) FMO-like PF00743.14 KPI36748.1 - 4.7e-08 31.6 0.2 2.2e-07 29.5 0.1 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI36748.1 - 1.4e-05 24.9 0.0 4.9e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI36748.1 - 5.7e-05 22.1 0.0 0.0015 17.5 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) bZIP_1 PF00170.16 KPI36748.1 - 0.00029 20.7 10.7 0.0016 18.3 7.4 2.2 1 1 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 KPI36748.1 - 0.0071 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper FB_lectin PF07367.6 KPI36748.1 - 0.084 12.4 0.5 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 Fungal fruit body lectin Peptidase_C78 PF07910.8 KPI36750.1 - 2.3e-54 183.8 0.0 3.3e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 KPI36750.1 - 0.0059 16.7 0.2 0.014 15.5 0.1 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Hira PF07569.6 KPI36751.1 - 3.9e-81 271.4 0.0 7.8e-81 270.4 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 KPI36751.1 - 1.3e-40 135.8 13.8 1.2e-07 31.3 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Band_7 PF01145.20 KPI36751.1 - 3.5e-29 101.9 0.2 5.8e-29 101.2 0.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family HIRA_B PF09453.5 KPI36751.1 - 0.0053 16.2 0.9 0.0086 15.6 0.1 1.9 2 0 0 2 2 2 1 HIRA B motif eIF2A PF08662.6 KPI36751.1 - 0.0065 16.1 0.1 1.2 8.8 0.1 3.8 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KPI36751.1 - 0.11 10.2 0.0 0.2 9.4 0.0 1.3 1 0 0 1 1 1 0 IKI3 family PALP PF00291.20 KPI36753.1 - 2.1e-44 152.0 4.3 2.5e-44 151.7 3.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme VCBS PF13517.1 KPI36754.1 - 0.11 12.9 1.6 0.38 11.1 0.0 2.8 3 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella F-box PF00646.28 KPI36755.1 - 0.00018 21.0 0.5 0.00032 20.2 0.3 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KPI36755.1 - 0.0026 17.4 0.3 0.0043 16.7 0.2 1.3 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KPI36755.1 - 0.0055 16.4 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 F-box-like domain DUF3425 PF11905.3 KPI36757.1 - 2.5e-11 43.5 0.3 6.7e-11 42.2 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) Sugar_tr PF00083.19 KPI36758.1 - 1.5e-69 234.7 26.9 1.9e-69 234.4 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI36758.1 - 1.7e-13 50.0 51.3 2.2e-09 36.5 20.9 2.6 1 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KPI36758.1 - 0.014 15.1 4.8 0.28 10.9 0.4 2.9 2 0 0 2 2 2 0 MFS_1 like family CTI PF06934.6 KPI36758.1 - 0.13 10.5 0.0 0.2 9.8 0.0 1.2 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) Pro_CA PF00484.14 KPI36759.1 - 3.4e-18 66.0 0.0 4.1e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Ribosomal_S14 PF00253.16 KPI36760.1 - 5.4e-14 51.2 1.6 2e-13 49.4 0.3 2.1 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e QLQ PF08880.6 KPI36760.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 QLQ Myb_DNA-binding PF00249.26 KPI36762.1 - 0.04 13.9 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Cyt-b5 PF00173.23 KPI36763.1 - 4.2e-08 32.8 0.0 8.1e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.13 KPI36763.1 - 0.0051 15.3 0.2 1.2 7.4 0.0 2.4 2 0 0 2 2 2 2 Indoleamine 2,3-dioxygenase FAD_binding_1 PF00667.15 KPI36763.1 - 0.02 14.3 0.0 0.05 13.0 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain Sugar_tr PF00083.19 KPI36764.1 - 7.3e-85 285.2 19.4 8.6e-85 284.9 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI36764.1 - 1.1e-22 80.2 42.2 2.4e-15 56.0 12.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KPI36764.1 - 0.0039 17.1 5.3 0.93 9.5 0.1 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF1228) Rick_17kDa_Anti PF05433.10 KPI36764.1 - 0.049 13.2 5.3 0.25 11.0 3.7 2.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 KPI36764.1 - 0.078 12.6 3.1 0.31 10.7 2.2 2.0 1 0 0 1 1 1 0 Glycine zipper DIOX_N PF14226.1 KPI36765.1 - 4.9e-27 94.7 0.0 8.5e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI36765.1 - 1.6e-17 63.5 0.0 4.6e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.19 KPI36766.1 - 6.8e-08 31.5 6.3 7.5e-08 31.3 4.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2215 PF10225.4 KPI36766.1 - 0.12 11.8 2.0 0.16 11.3 1.4 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF1049 PF06305.6 KPI36766.1 - 0.31 10.5 3.7 0.34 10.4 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF3405 PF11885.3 KPI36767.1 - 4.6e-162 539.7 0.7 5.8e-162 539.3 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DUF1524 PF07510.6 KPI36769.1 - 3.2e-13 49.7 0.0 4e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Whi5 PF08528.6 KPI36771.1 - 5.1e-10 38.6 0.3 9.8e-10 37.7 0.2 1.5 1 0 0 1 1 1 1 Whi5 like zf-CCHC PF00098.18 KPI36773.1 - 0.027 14.3 11.8 0.049 13.5 3.0 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 KPI36773.1 - 1.6 8.4 8.2 0.1 12.2 1.4 2.2 2 0 0 2 2 2 0 Zinc knuckle Elf1 PF05129.8 KPI36773.1 - 3 7.5 7.2 1.6 8.4 2.3 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 KPI36773.1 - 9.3 6.0 9.9 34 4.2 0.7 3.5 3 0 0 3 3 3 0 zinc-ribbon domain IU_nuc_hydro PF01156.14 KPI36775.1 - 2.8e-77 260.0 0.0 3.4e-77 259.7 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase p450 PF00067.17 KPI36776.1 - 1e-42 146.2 0.0 3.6e-40 137.8 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Oxidored_q6 PF01058.17 KPI36778.1 - 1.1e-21 76.8 0.0 1.7e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit HEAT PF02985.17 KPI36779.1 - 9.6e-44 143.5 17.1 0.0016 18.3 0.1 13.2 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 KPI36779.1 - 9.8e-34 115.5 1.7 4.2e-08 33.3 0.0 7.5 2 2 5 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.2 KPI36779.1 - 1.1e-13 51.4 0.6 6.1e-05 23.3 0.1 6.9 4 2 4 8 8 8 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KPI36779.1 - 2.5e-09 37.3 11.7 0.16 12.5 0.0 9.0 6 3 4 10 10 10 2 HEAT-like repeat Adaptin_N PF01602.15 KPI36779.1 - 1.6e-06 26.7 6.3 0.0076 14.6 0.2 4.6 1 1 2 3 3 3 3 Adaptin N terminal region CLASP_N PF12348.3 KPI36779.1 - 1.6e-05 24.3 0.6 0.029 13.7 0.0 4.3 2 2 1 4 4 4 1 CLASP N terminal DUF2435 PF10363.4 KPI36779.1 - 0.011 15.6 4.2 9.4 6.2 0.1 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2435) Cnd3 PF12719.2 KPI36779.1 - 0.093 11.7 0.1 0.43 9.4 0.1 2.2 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Proteasom_PSMB PF10508.4 KPI36779.1 - 0.45 8.7 3.0 0.76 7.9 0.1 2.5 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit Arm PF00514.18 KPI36779.1 - 1.3 8.9 8.5 3.3 7.6 0.0 4.7 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Asp PF00026.18 KPI36780.1 - 1.3e-24 87.0 3.7 1.5e-24 86.8 2.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KPI36780.1 - 0.0099 16.3 1.3 0.039 14.4 0.4 2.4 2 1 0 2 2 2 1 Aspartyl protease COesterase PF00135.23 KPI36781.1 - 6e-64 216.6 0.0 8e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI36781.1 - 0.027 14.0 0.1 0.17 11.4 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold RVT_1 PF00078.22 KPI36782.1 - 7.9e-05 22.1 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mononeg_mRNAcap PF14318.1 KPI36785.1 - 0.079 11.9 0.0 0.079 11.9 0.0 1.1 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V A_deaminase PF00962.17 KPI36786.1 - 1.6e-70 237.6 0.0 1.8e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 KPI36786.1 - 0.012 15.6 0.4 0.032 14.2 0.2 1.6 1 1 0 1 1 1 0 Amidohydrolase DHquinase_II PF01220.14 KPI36787.1 - 5e-55 184.6 0.0 5.7e-55 184.4 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Abhydrolase_3 PF07859.8 KPI36788.1 - 9.3e-40 136.4 0.1 1.3e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI36788.1 - 3.3e-07 30.1 0.1 4.9e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KPI36788.1 - 5.1e-07 28.7 0.4 2.2e-06 26.6 0.3 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KPI36788.1 - 0.00087 18.5 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 KPI36788.1 - 0.0011 17.5 0.0 0.0024 16.4 0.0 1.5 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF2424 PF10340.4 KPI36788.1 - 0.012 14.2 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Esterase_phd PF10503.4 KPI36788.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Radical_SAM PF04055.16 KPI36790.1 - 7.3e-14 52.2 0.0 1.2e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HMA PF00403.21 KPI36791.1 - 9.2e-16 57.7 0.2 1.1e-15 57.4 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain CGGC PF08821.6 KPI36791.1 - 0.074 13.1 0.1 0.083 12.9 0.0 1.1 1 0 0 1 1 1 0 CGGC domain DUF1677 PF07911.8 KPI36791.1 - 0.084 13.0 0.0 0.088 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) Toxin-deaminase PF14424.1 KPI36791.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases Acyl_transf_3 PF01757.17 KPI36792.1 - 5.1e-33 114.3 32.4 7.6e-33 113.7 22.5 1.2 1 0 0 1 1 1 1 Acyltransferase family DUF2892 PF11127.3 KPI36792.1 - 0.11 12.3 0.6 10 6.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) MFS_1 PF07690.11 KPI36793.1 - 2.3e-39 135.1 21.4 2.3e-39 135.1 14.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KPI36793.1 - 0.066 11.3 5.1 0.1 10.7 3.5 1.3 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) IncA PF04156.9 KPI36796.1 - 0.029 13.9 0.1 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 IncA protein Epsilon_antitox PF08998.6 KPI36796.1 - 0.073 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Bacterial epsilon antitoxin TGS PF02824.16 KPI36797.1 - 1.3e-22 79.3 0.1 2.6e-22 78.3 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KPI36797.1 - 5.2e-18 65.0 0.1 1.3e-17 63.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KPI36797.1 - 3.2e-09 36.2 0.0 1.8e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KPI36797.1 - 8.8e-05 22.0 0.2 1.4 8.2 0.0 3.9 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KPI36797.1 - 0.0006 19.6 0.1 0.13 12.1 0.0 2.4 1 1 1 2 2 2 1 Dynamin family ArgK PF03308.11 KPI36797.1 - 0.0049 15.6 0.2 0.013 14.2 0.1 1.8 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 KPI36797.1 - 0.0082 16.6 0.0 0.026 15.0 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein DUF211 PF02680.9 KPI36797.1 - 0.045 13.5 0.3 0.16 11.7 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized ArCR, COG1888 CCD PF07860.6 KPI36797.1 - 0.13 11.7 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 WisP family C-Terminal Region AAA_28 PF13521.1 KPI36797.1 - 0.13 12.2 0.1 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain DHquinase_I PF01487.10 KPI36798.1 - 9.7e-32 110.4 0.0 1.4e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 KPI36798.1 - 4.1e-17 62.0 0.1 1.2e-16 60.4 0.1 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 KPI36798.1 - 1.4e-16 60.7 0.1 2.8e-16 59.7 0.0 1.6 2 0 0 2 2 2 1 Shikimate kinase Shikimate_DH PF01488.15 KPI36798.1 - 9.2e-12 45.2 0.0 2.8e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF3086 PF11285.3 KPI36798.1 - 0.029 13.2 0.0 4.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) Fungal_trans PF04082.13 KPI36799.1 - 1.5e-05 24.0 0.1 2.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 KPI36800.1 - 5.9e-68 229.4 21.3 7.3e-68 229.1 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI36800.1 - 5.5e-18 64.7 24.4 5.5e-18 64.7 16.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sedlin_N PF04628.8 KPI36801.1 - 6.2e-17 61.7 0.0 8.5e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF2293 PF10056.4 KPI36802.1 - 1.1e-25 89.4 0.0 3e-25 87.9 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Glyco_transf_90 PF05686.7 KPI36803.1 - 2.3e-20 72.6 1.5 8.1e-17 60.9 0.5 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 RRS1 PF04939.7 KPI36803.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) Na_H_Exchanger PF00999.16 KPI36804.1 - 4.7e-51 173.4 19.2 6.1e-51 173.1 13.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family OPT PF03169.10 KPI36807.1 - 3.7e-91 306.4 24.9 4.5e-91 306.1 17.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein AMP-binding PF00501.23 KPI36809.1 - 1.1e-25 89.9 1.2 8e-25 87.0 0.8 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Sugar_tr PF00083.19 KPI36810.1 - 3.3e-82 276.4 14.5 3.9e-82 276.2 10.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI36810.1 - 7.4e-14 51.2 45.9 2.7e-12 46.0 20.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI36810.1 - 0.0017 16.8 21.9 0.0031 15.9 1.6 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein Laminin_G_3 PF13385.1 KPI36812.1 - 5.9e-05 23.3 0.3 5.9e-05 23.3 0.2 2.4 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily Gly_transf_sug PF04488.10 KPI36813.1 - 1.3e-12 48.0 0.3 2.5e-12 47.1 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KPI36813.1 - 0.043 12.2 1.8 0.15 10.4 0.1 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 KPI36813.1 - 0.054 12.6 0.1 0.08 12.0 0.1 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Sulfatase PF00884.18 KPI36814.1 - 3.6e-17 62.5 0.1 7.5e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KPI36814.1 - 2e-06 27.3 0.0 3.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KPI36814.1 - 0.0094 14.4 0.0 0.014 13.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF3712 PF12505.3 KPI36815.1 - 1.8e-26 92.6 0.5 2.7e-25 88.7 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 KPI36815.1 - 6e-05 23.3 0.9 0.093 13.1 0.1 2.4 2 0 0 2 2 2 2 Late embryogenesis abundant protein DUF805 PF05656.9 KPI36815.1 - 0.028 14.2 0.2 0.047 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF1279 PF06916.8 KPI36815.1 - 0.055 13.7 0.5 0.082 13.2 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) Glyco_hydro_16 PF00722.16 KPI36816.1 - 3.8e-11 42.6 0.0 3.8e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 PAT1 PF09770.4 KPI36816.1 - 0.92 7.6 26.1 1.2 7.3 18.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PRP1_N PF06424.7 KPI36817.1 - 0.021 15.1 6.1 0.16 12.2 0.3 2.3 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal Isochorismatase PF00857.15 KPI36818.1 - 2.3e-18 66.7 0.0 3.4e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family TrbH PF07283.6 KPI36818.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Conjugal transfer protein TrbH TauD PF02668.11 KPI36819.1 - 4.8e-40 137.8 0.3 5.4e-40 137.6 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pkinase PF00069.20 KPI36820.1 - 6.1e-27 94.4 0.0 7.9e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI36820.1 - 2.2e-12 46.6 0.0 3.1e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KPI36820.1 - 9.5e-06 25.5 0.0 0.0014 18.4 0.0 2.5 2 1 0 3 3 3 2 Phosphotransferase enzyme family MSP1_C PF07462.6 KPI36821.1 - 1.5 7.1 3.6 5 5.3 0.9 2.2 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus AhpC-TSA PF00578.16 KPI36822.1 - 1.5e-26 92.4 0.0 2.5e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KPI36822.1 - 1.7e-19 69.7 0.0 2.5e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KPI36822.1 - 0.00037 20.3 0.0 0.001 19.0 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme F-box-like PF12937.2 KPI36823.1 - 0.014 15.0 0.0 0.082 12.6 0.0 2.1 1 1 0 1 1 1 0 F-box-like PMBR PF09373.5 KPI36824.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 Pseudomurein-binding repeat E1-E2_ATPase PF00122.15 KPI36825.1 - 1e-46 158.8 0.7 2.2e-46 157.7 0.5 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KPI36825.1 - 3.4e-40 137.5 5.4 3.4e-40 137.5 3.7 3.2 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KPI36825.1 - 4.4e-31 108.9 0.0 2.4e-30 106.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KPI36825.1 - 5.7e-17 61.4 0.0 1.2e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KPI36825.1 - 1.1e-12 47.2 0.0 2.6e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KPI36825.1 - 1.1e-12 48.5 0.0 2.7e-12 47.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KPI36825.1 - 4.7e-05 23.0 0.1 0.0001 21.9 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase bZIP_1 PF00170.16 KPI36828.1 - 1.6e-05 24.7 10.5 1.6e-05 24.7 7.3 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 KPI36828.1 - 1.4 9.2 12.9 6.6 7.0 8.2 2.3 2 1 0 2 2 2 0 bZIP Maf transcription factor TPR_10 PF13374.1 KPI36828.1 - 1.5 8.8 3.7 1 9.3 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3531 PF12049.3 KPI36829.1 - 0.12 12.0 0.3 0.29 10.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3531) Fungal_trans PF04082.13 KPI36831.1 - 0.0009 18.1 0.2 0.0014 17.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain UNC-93 PF05978.11 KPI36832.1 - 1.4e-13 50.6 4.8 1.4e-13 50.6 3.4 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KPI36832.1 - 6.2e-09 35.0 32.9 6.2e-09 35.0 22.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily HemX PF04375.9 KPI36832.1 - 0.12 10.9 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 HemX Zn_clus PF00172.13 KPI36833.1 - 2.6e-09 36.8 7.6 4.6e-09 36.0 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PXA PF02194.10 KPI36834.1 - 2.1e-37 128.4 0.1 2.1e-37 128.4 0.1 2.1 2 0 0 2 2 2 1 PXA domain Ribosomal_L31 PF01197.13 KPI36834.1 - 0.022 14.7 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L31 Inositol_P PF00459.20 KPI36835.1 - 4.7e-75 252.3 0.0 5.1e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family COesterase PF00135.23 KPI36837.1 - 1.4e-85 288.0 0.1 6.8e-80 269.2 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI36837.1 - 2.7e-09 36.9 0.0 4.7e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI36837.1 - 0.048 13.4 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI36837.1 - 0.08 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family F-box-like PF12937.2 KPI36838.1 - 0.00018 21.1 0.0 0.15 11.7 0.0 2.9 2 1 0 2 2 2 2 F-box-like F-box PF00646.28 KPI36838.1 - 0.075 12.7 2.6 9.9 5.9 0.3 3.6 3 1 0 3 3 3 0 F-box domain Ribosomal_S3_C PF00189.15 KPI36839.1 - 1.2e-16 60.6 0.1 2.4e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KPI36839.1 - 1.2e-12 47.2 0.1 2e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 KPI36839.1 - 0.055 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DIOX_N PF14226.1 KPI36840.1 - 6.6e-18 65.3 0.3 1.5e-17 64.1 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI36840.1 - 2.4e-14 53.4 0.0 4.5e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosomal_L13 PF00572.13 KPI36841.1 - 5.7e-28 97.5 0.0 1.1e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 HET PF06985.6 KPI36843.1 - 5.9e-25 88.0 0.1 8.2e-25 87.5 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 KPI36846.1 - 9.8e-27 93.9 1.7 1.6e-26 93.2 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI36846.1 - 8.3e-13 48.6 0.1 1.2e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI36846.1 - 2.5e-09 37.0 0.4 4.3e-09 36.2 0.3 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI36846.1 - 6e-06 25.8 0.2 9.3e-06 25.2 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family S-AdoMet_synt_C PF02773.11 KPI36846.1 - 4.5 6.9 8.5 7.6 6.2 0.6 2.9 2 1 1 3 3 3 0 S-adenosylmethionine synthetase, C-terminal domain ABC_tran PF00005.22 KPI36847.1 - 5.5e-19 68.8 0.3 1.8e-16 60.6 0.2 2.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KPI36847.1 - 2e-08 34.5 0.0 0.00057 19.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KPI36847.1 - 7.6e-05 22.3 0.1 0.32 10.7 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_17 PF13207.1 KPI36847.1 - 0.00019 22.2 0.0 0.0005 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 KPI36847.1 - 0.00025 20.3 0.1 0.0015 17.8 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 KPI36847.1 - 0.00028 21.2 0.0 0.00063 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KPI36847.1 - 0.0003 20.7 0.4 0.00087 19.2 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KPI36847.1 - 0.00063 19.8 2.2 0.002 18.2 0.3 2.6 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KPI36847.1 - 0.00065 19.2 0.6 0.0012 18.3 0.4 1.5 1 1 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 KPI36847.1 - 0.0037 16.7 0.0 0.0077 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 KPI36847.1 - 0.0038 17.0 0.4 0.0096 15.8 0.3 1.7 1 0 0 1 1 1 1 AAA domain AAA_13 PF13166.1 KPI36847.1 - 0.0079 14.7 1.6 0.021 13.3 0.2 2.1 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KPI36847.1 - 0.0083 16.4 4.1 0.021 15.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 KPI36847.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_15 PF13175.1 KPI36847.1 - 0.032 13.2 0.0 3.2 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 KPI36847.1 - 0.067 13.3 0.1 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KPI36847.1 - 0.12 12.3 11.3 0.33 10.8 6.6 2.5 1 1 1 2 2 2 0 AAA ATPase domain SlyX PF04102.7 KPI36848.1 - 0.11 12.9 0.2 2.9 8.3 0.0 3.0 4 0 0 4 4 4 0 SlyX Ribosomal_L3 PF00297.17 KPI36849.1 - 3.2e-31 108.7 2.8 1.7e-29 103.0 2.2 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 ADH_zinc_N PF00107.21 KPI36850.1 - 6.3e-24 83.9 0.1 9.1e-24 83.4 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI36850.1 - 4e-13 50.3 0.0 7e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI36850.1 - 3.3e-08 33.2 0.0 6.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KPI36850.1 - 0.05 13.1 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 KPI36850.1 - 0.092 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NmrA PF05368.8 KPI36851.1 - 7.6e-26 90.7 0.0 1.5e-23 83.3 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI36851.1 - 4e-05 23.6 0.0 8.2e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 KPI36851.1 - 0.005 16.5 0.0 0.0094 15.6 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KPI36851.1 - 0.0055 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KPI36851.1 - 0.043 13.2 0.1 0.2 11.0 0.0 2.2 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family PGM_PMM_III PF02880.11 KPI36852.1 - 1.9e-12 47.1 0.0 4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 KPI36852.1 - 3.4e-09 36.5 0.0 2.8e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 KPI36852.1 - 5.8e-08 33.0 0.0 1.3e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.11 KPI36852.1 - 4.1e-07 29.5 0.0 1.8e-06 27.4 0.0 2.2 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I YchF-GTPase_C PF06071.8 KPI36853.1 - 1.6e-32 111.1 0.3 3.5e-32 110.0 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KPI36853.1 - 9.3e-13 48.1 0.0 2e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KPI36853.1 - 0.0017 17.6 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 KPI36853.1 - 0.0051 16.6 0.1 0.016 15.0 0.1 1.9 1 0 0 1 1 1 1 TGS domain AAA_23 PF13476.1 KPI36853.1 - 0.087 13.1 1.9 0.36 11.1 1.2 2.0 1 1 0 1 1 1 0 AAA domain Beta-lactamase PF00144.19 KPI36854.1 - 7.8e-20 71.1 1.5 2.3e-19 69.6 1.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Transp_cyt_pur PF02133.10 KPI36855.1 - 7.4e-89 298.2 34.5 8.6e-89 298.0 23.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin B3_4 PF03483.12 KPI36857.1 - 6.8e-26 90.7 0.0 1.1e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KPI36857.1 - 4.9e-18 64.7 0.0 4.5e-15 55.2 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain SLS PF14611.1 KPI36857.1 - 0.057 12.8 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator LMBR1 PF04791.11 KPI36858.1 - 1.3e-31 109.7 5.7 1.6e-31 109.4 4.0 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein GvpK PF05121.7 KPI36858.1 - 0.063 13.0 0.6 0.12 12.2 0.4 1.4 1 0 0 1 1 1 0 Gas vesicle protein K IncA PF04156.9 KPI36858.1 - 0.15 11.6 0.0 0.15 11.6 0.0 2.5 3 0 0 3 3 3 0 IncA protein DUF3675 PF12428.3 KPI36858.1 - 2.8 8.2 6.2 6.4 7.0 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) WD40 PF00400.27 KPI36860.1 - 5.9e-15 54.4 4.5 0.00021 21.0 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KPI36860.1 - 4.2e-05 23.1 0.4 0.051 13.0 0.1 2.2 2 0 0 2 2 2 2 PQQ-like domain DUF3312 PF11768.3 KPI36860.1 - 0.0029 15.9 0.0 0.0029 15.9 0.0 1.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3312) adh_short PF00106.20 KPI36861.1 - 6.8e-26 91.1 1.7 6.7e-24 84.6 1.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI36861.1 - 1.8e-18 67.1 0.5 3.6e-17 62.9 0.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI36861.1 - 3.4e-08 33.3 3.2 6.2e-07 29.2 0.0 2.3 1 1 1 2 2 2 1 KR domain DUF1776 PF08643.5 KPI36861.1 - 0.0011 18.2 0.1 0.0016 17.6 0.1 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.15 KPI36861.1 - 0.0032 17.5 0.1 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DEDD_Tnp_IS110 PF01548.12 KPI36861.1 - 0.0051 16.4 0.0 11 5.6 0.0 3.1 3 0 0 3 3 3 1 Transposase Pyr_redox PF00070.22 KPI36861.1 - 0.0062 16.9 0.7 0.014 15.7 0.3 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KPI36861.1 - 0.011 15.2 0.1 0.042 13.2 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.10 KPI36861.1 - 0.048 12.5 0.1 0.087 11.6 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FAD_binding_3 PF01494.14 KPI36861.1 - 0.057 12.4 0.9 0.092 11.7 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 KPI36861.1 - 0.082 12.5 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OPT PF03169.10 KPI36864.1 - 3.7e-59 200.7 17.9 4.1e-59 200.5 12.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PIN_4 PF13638.1 KPI36864.1 - 0.033 14.2 0.1 0.049 13.7 0.1 1.2 1 0 0 1 1 1 0 PIN domain DUF2207 PF09972.4 KPI36864.1 - 0.12 10.9 0.0 0.76 8.2 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Pyr_redox_3 PF13738.1 KPI36866.1 - 4.8e-20 72.4 0.0 8.7e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI36866.1 - 7.7e-12 44.1 0.0 3.7e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI36866.1 - 9.7e-09 35.1 0.6 2e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI36866.1 - 1.5e-07 30.6 0.3 0.0037 16.2 0.1 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KPI36866.1 - 0.0043 16.8 0.1 0.037 13.7 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 KPI36866.1 - 0.0045 16.1 0.0 0.017 14.2 0.0 1.9 2 0 0 2 2 2 1 Thi4 family ABC_tran PF00005.22 KPI36867.1 - 1.3e-11 44.9 0.0 4e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KPI36867.1 - 3.5e-08 33.7 0.1 4e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 KPI36867.1 - 3.9e-05 22.9 0.0 5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KPI36867.1 - 0.0087 15.9 0.6 0.079 12.8 0.4 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Fungal_trans_2 PF11951.3 KPI36868.1 - 0.0099 14.5 0.5 0.043 12.4 0.3 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_2 PF00891.13 KPI36869.1 - 2.2e-29 102.3 0.1 9.1e-29 100.3 0.1 1.9 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KPI36869.1 - 0.0014 19.2 0.0 0.0034 17.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI36869.1 - 0.0035 17.0 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI36869.1 - 0.013 15.9 0.0 0.036 14.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain cobW PF02492.14 KPI36869.1 - 0.038 13.4 0.2 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF745 PF05335.8 KPI36869.1 - 0.73 9.3 6.7 0.16 11.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Cu_bind_like PF02298.12 KPI36870.1 - 0.017 14.8 0.1 0.058 13.1 0.1 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain CDO_I PF05995.7 KPI36871.1 - 2.4e-36 124.5 0.0 3.2e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KPI36871.1 - 2.4e-06 27.0 0.0 3.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) GFA PF04828.9 KPI36873.1 - 1.3e-19 69.8 0.3 2.2e-19 69.1 0.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 KPI36873.1 - 0.029 14.1 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Rpr2 PF04032.11 KPI36873.1 - 0.14 12.0 1.5 0.16 11.8 0.0 1.8 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Pkinase PF00069.20 KPI36874.1 - 1.5e-06 27.5 0.0 2.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PAT1 PF09770.4 KPI36874.1 - 0.043 12.0 15.1 0.058 11.6 10.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Acetyltransf_1 PF00583.19 KPI36875.1 - 3.8e-14 52.4 0.0 5.5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KPI36875.1 - 4e-07 30.1 0.0 5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KPI36875.1 - 8e-07 29.1 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KPI36875.1 - 1.2e-05 24.9 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KPI36875.1 - 6.1e-05 23.1 0.0 6.9e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KPI36875.1 - 0.00012 21.8 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 KPI36875.1 - 0.00077 19.3 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KPI36875.1 - 0.0081 16.0 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Redoxin PF08534.5 KPI36876.1 - 3.3e-24 85.0 0.0 3.7e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KPI36876.1 - 3.3e-10 39.7 0.0 4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Transp_cyt_pur PF02133.10 KPI36877.1 - 1.4e-87 294.1 37.8 1.7e-87 293.8 26.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Bromodomain PF00439.20 KPI36878.1 - 5.5e-37 125.5 2.4 3e-19 68.7 0.7 2.7 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 KPI36878.1 - 5.5e-14 51.9 0.6 1.2e-13 50.8 0.4 1.6 1 0 0 1 1 1 1 BAH domain Glyco_transf_15 PF01793.11 KPI36879.1 - 1.8e-89 299.9 0.0 2.2e-89 299.7 0.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase adh_short PF00106.20 KPI36883.1 - 3.8e-19 69.2 1.5 5.3e-11 42.7 0.2 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KPI36883.1 - 3.4e-08 33.3 0.5 0.00015 21.4 0.1 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KPI36883.1 - 4.1e-07 30.0 0.0 1.6e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KPI36883.1 - 0.0003 20.8 0.1 0.063 13.2 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KPI36883.1 - 0.00032 20.2 0.0 0.002 17.6 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 KPI36883.1 - 0.005 17.3 0.2 0.034 14.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI36883.1 - 0.0074 16.3 0.4 0.012 15.6 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 KPI36883.1 - 0.036 13.8 0.2 0.12 12.2 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_31 PF13847.1 KPI36883.1 - 0.054 13.0 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.13 KPI36883.1 - 0.063 12.9 0.1 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.10 KPI36883.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.14 KPI36883.1 - 0.11 11.5 0.1 0.54 9.3 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short PF00106.20 KPI36884.1 - 2.7e-20 72.9 2.0 4.2e-20 72.3 0.3 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KPI36884.1 - 1e-08 35.0 0.2 1.3e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KPI36884.1 - 2.4e-08 34.0 0.3 1.2e-07 31.7 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KPI36884.1 - 0.0044 16.4 0.1 0.0085 15.5 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1183 PF06682.7 KPI36885.1 - 0.047 13.3 0.2 0.047 13.3 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) CAF-1_p150 PF11600.3 KPI36885.1 - 0.079 12.3 43.6 0.0095 15.3 26.0 1.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 KPI36885.1 - 0.23 11.3 13.4 0.38 10.6 9.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIIAH PF12685.2 KPI36885.1 - 0.24 10.8 8.8 0.35 10.3 5.8 1.5 1 1 0 1 1 1 0 SpoIIIAH-like protein Shisa PF13908.1 KPI36885.1 - 0.24 11.5 3.6 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF1510 PF07423.6 KPI36885.1 - 0.26 10.6 17.2 0.62 9.3 11.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) PA26 PF04636.8 KPI36885.1 - 0.3 9.7 6.2 0.4 9.3 4.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MIP-T3 PF10243.4 KPI36885.1 - 0.65 8.4 35.2 0.82 8.0 24.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Borrelia_P83 PF05262.6 KPI36885.1 - 0.81 7.8 14.9 1.4 7.0 10.3 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF390 PF04094.9 KPI36885.1 - 2.5 6.0 15.9 4.3 5.2 11.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Presenilin PF01080.12 KPI36885.1 - 3.8 6.2 5.2 5.4 5.7 3.6 1.2 1 0 0 1 1 1 0 Presenilin Phosducin PF02114.11 KPI36885.1 - 6.9 5.3 11.6 11 4.6 8.1 1.2 1 0 0 1 1 1 0 Phosducin Ycf1 PF05758.7 KPI36885.1 - 8.5 3.9 11.6 11 3.6 8.0 1.1 1 0 0 1 1 1 0 Ycf1 Arb2 PF09757.4 KPI36886.1 - 2.7e-14 52.9 0.0 4.4e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Sugar_tr PF00083.19 KPI36888.1 - 2.4e-63 214.2 9.9 3.4e-63 213.7 6.6 1.3 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI36888.1 - 5.1e-27 94.5 21.4 6.7e-27 94.1 14.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KPI36888.1 - 0.0075 16.0 0.3 0.25 11.1 0.0 3.0 2 1 1 3 3 3 1 MFS_1 like family DUF554 PF04474.7 KPI36888.1 - 0.01 15.0 2.2 0.01 15.0 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF554) TRI12 PF06609.8 KPI36888.1 - 0.034 12.3 4.5 0.023 12.9 1.5 1.7 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF2762 PF10960.3 KPI36888.1 - 0.12 12.0 0.1 0.39 10.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) STE3 PF02076.10 KPI36889.1 - 4.7e-36 124.3 16.5 5.9e-36 123.9 11.4 1.2 1 1 0 1 1 1 1 Pheromone A receptor Sugar_tr PF00083.19 KPI36890.1 - 2.2e-89 300.1 30.5 8.3e-52 176.2 9.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI36890.1 - 3.8e-20 71.9 38.5 2.8e-15 55.9 7.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Mem_trans PF03547.13 KPI36890.1 - 2.8 6.1 8.1 0.61 8.3 3.0 1.8 2 0 0 2 2 2 0 Membrane transport protein PXA PF02194.10 KPI36891.1 - 0.089 12.3 0.2 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 PXA domain WHIM1 PF15612.1 KPI36892.1 - 0.0013 18.5 0.0 0.0033 17.2 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Daxx PF03344.10 KPI36892.1 - 0.049 12.1 8.5 0.096 11.1 5.9 1.4 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KPI36892.1 - 0.65 7.8 11.8 1.3 6.8 8.2 1.4 1 0 0 1 1 1 0 Nop14-like family CTP_transf_2 PF01467.21 KPI36894.1 - 5.2e-20 72.0 0.0 8.8e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase ATG16 PF08614.6 KPI36895.1 - 0.11 12.2 19.7 0.37 10.5 13.6 1.8 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 KPI36895.1 - 1 7.7 17.7 1.6 7.1 12.2 1.2 1 0 0 1 1 1 0 AAA domain DUF706 PF05153.10 KPI36896.1 - 7.1e-94 313.8 0.1 9.6e-94 313.4 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 KPI36896.1 - 0.033 14.2 0.1 2.1 8.3 0.0 2.7 2 1 0 3 3 3 0 HD domain Elong_Iki1 PF10483.4 KPI36897.1 - 3.7e-71 239.7 0.0 4.4e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 WD40 PF00400.27 KPI36898.1 - 1.2e-30 104.2 0.3 2.9e-06 26.9 0.0 8.2 8 0 0 8 8 8 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KPI36898.1 - 0.006 16.0 0.0 4.4 6.8 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 KPI36898.1 - 0.035 12.2 0.1 2.9 5.9 0.0 2.5 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KPI36898.1 - 0.12 11.1 0.0 12 4.4 0.0 2.4 1 1 0 2 2 2 0 Nup133 N terminal like Acetyltransf_7 PF13508.1 KPI36899.1 - 7.8e-11 41.9 0.1 3.1e-10 40.0 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KPI36899.1 - 5.3e-09 35.9 0.0 9.5e-09 35.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KPI36899.1 - 0.0002 21.4 0.5 0.00054 20.0 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 KPI36899.1 - 0.021 14.1 0.1 0.075 12.3 0.1 1.8 2 1 0 2 2 2 0 GNAT acetyltransferase 2 FR47 PF08445.5 KPI36899.1 - 0.03 14.0 0.0 0.076 12.7 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_9 PF13527.1 KPI36899.1 - 0.036 13.9 0.2 0.082 12.7 0.1 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KPI36899.1 - 0.042 13.7 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Fungal_trans PF04082.13 KPI36900.1 - 7e-14 51.3 0.5 1.1e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KPI36900.1 - 1.2e-11 44.2 6.7 3.4e-05 23.9 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI36900.1 - 3e-10 39.6 8.0 0.00014 21.9 2.7 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KPI36900.1 - 3.7e-10 39.5 2.0 3.7e-10 39.5 1.4 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KPI36900.1 - 1.6e-05 24.9 0.1 0.089 12.9 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KPI36900.1 - 0.00023 20.9 2.7 0.55 10.2 0.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KPI36900.1 - 0.0014 18.2 3.2 0.36 10.5 0.7 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-Di19 PF05605.7 KPI36900.1 - 0.0031 17.5 3.0 0.0066 16.5 2.1 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KPI36900.1 - 0.031 14.4 0.7 9 6.6 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DHDPS PF00701.17 KPI36901.1 - 7.1e-39 133.1 0.0 8.3e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Radical_SAM PF04055.16 KPI36901.1 - 0.041 14.0 0.0 8.7 6.4 0.0 3.0 3 0 0 3 3 3 0 Radical SAM superfamily Pdase_C33_assoc PF14756.1 KPI36901.1 - 0.069 12.8 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 Peptidase_C33-associated domain MFS_1 PF07690.11 KPI36902.1 - 8.3e-32 110.2 28.1 8.3e-32 110.2 19.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Septin PF00735.13 KPI36904.1 - 5.4e-106 353.7 0.1 1.2e-105 352.5 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KPI36904.1 - 0.00013 21.8 0.0 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KPI36904.1 - 0.0003 20.6 4.5 0.25 11.1 0.0 3.1 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 KPI36904.1 - 0.00084 18.8 0.0 0.02 14.3 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KPI36904.1 - 0.0015 17.7 0.2 0.0039 16.3 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KPI36904.1 - 0.011 14.8 0.1 0.033 13.3 0.1 1.8 1 1 0 1 1 1 0 AIG1 family Miro PF08477.8 KPI36904.1 - 0.016 15.6 0.3 0.044 14.2 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 KPI36904.1 - 0.055 13.6 0.3 0.22 11.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain GBP_C PF02841.9 KPI36904.1 - 0.056 12.6 8.3 0.078 12.1 5.7 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain FtsK_SpoIIIE PF01580.13 KPI36904.1 - 0.088 12.2 0.0 0.088 12.2 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF3653 PF12375.3 KPI36904.1 - 0.095 12.9 1.9 2.2 8.5 0.7 2.8 2 1 0 2 2 2 0 Phage protein AAA_17 PF13207.1 KPI36904.1 - 0.31 11.8 4.1 0.68 10.7 0.1 2.8 2 2 0 2 2 2 0 AAA domain APG6 PF04111.7 KPI36904.1 - 0.88 8.5 6.8 1.4 7.8 4.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 KPI36904.1 - 4 5.1 6.3 5.9 4.6 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YIF1 PF03878.10 KPI36906.1 - 7.2e-77 257.7 4.6 9.1e-77 257.4 3.2 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 KPI36906.1 - 0.00035 20.1 4.7 0.00035 20.1 3.3 2.0 2 0 0 2 2 2 1 Yip1 domain tRNA-synt_1e PF01406.14 KPI36907.1 - 1.5e-106 355.8 0.2 2e-106 355.5 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KPI36907.1 - 0.00016 20.4 1.1 0.22 10.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Sod_Cu PF00080.15 KPI36908.1 - 6.4e-46 156.0 6.1 7.3e-46 155.8 4.2 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) His_Phos_2 PF00328.17 KPI36909.1 - 5e-39 134.5 0.0 1.9e-38 132.7 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 KPI36909.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) adh_short PF00106.20 KPI36910.1 - 6.5e-22 78.2 0.1 6.5e-22 78.2 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI36910.1 - 5.1e-06 26.4 0.0 1.2e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI36910.1 - 1.1e-05 25.2 3.0 0.00014 21.5 0.0 2.9 3 0 0 3 3 3 1 KR domain NAD_binding_1 PF00175.16 KPI36910.1 - 0.005 17.4 0.0 0.054 14.0 0.0 2.7 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain 3HCDH_N PF02737.13 KPI36910.1 - 0.0061 16.2 0.1 0.0061 16.2 0.1 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_26 PF13659.1 KPI36910.1 - 0.011 15.8 0.0 0.03 14.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 KPI36910.1 - 0.02 14.8 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.16 KPI36910.1 - 0.028 13.8 0.1 0.067 12.6 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_6 PF08030.7 KPI36910.1 - 0.053 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Pyr_redox_3 PF13738.1 KPI36910.1 - 0.088 12.8 1.2 0.21 11.5 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SNF2_N PF00176.18 KPI36911.1 - 1.4e-27 96.2 0.0 1.4e-27 96.2 0.0 3.0 3 0 0 3 3 3 1 SNF2 family N-terminal domain HSA PF07529.8 KPI36911.1 - 2.4e-12 46.4 10.7 2.4e-12 46.4 7.4 3.0 2 1 1 3 3 3 1 HSA QLQ PF08880.6 KPI36911.1 - 1.3e-11 43.7 1.7 2.4e-11 42.8 0.3 2.3 2 0 0 2 2 2 1 QLQ ResIII PF04851.10 KPI36911.1 - 0.00034 20.4 0.0 0.00034 20.4 0.0 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Exo_endo_phos PF03372.18 KPI36912.1 - 1.2e-23 84.3 0.1 1.4e-23 84.1 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KPI36912.1 - 0.056 13.0 0.0 1.1 8.8 0.0 2.5 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase Longin PF13774.1 KPI36913.1 - 5.8e-30 102.6 0.9 9.6e-30 101.9 0.6 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KPI36913.1 - 3e-15 55.5 0.1 8.1e-15 54.2 0.0 1.7 2 0 0 2 2 2 1 Synaptobrevin DUF1664 PF07889.7 KPI36913.1 - 0.013 15.3 1.3 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF334 PF03904.8 KPI36913.1 - 0.092 12.0 0.3 7.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF334) PilJ PF13675.1 KPI36913.1 - 0.28 11.5 3.3 1.6 9.0 0.2 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Macoilin PF09726.4 KPI36914.1 - 1.8 6.7 6.9 2.9 6.0 4.8 1.2 1 0 0 1 1 1 0 Transmembrane protein BTB PF00651.26 KPI36916.1 - 4.6e-13 49.1 0.7 1.5e-12 47.4 0.1 2.0 1 1 0 2 2 2 1 BTB/POZ domain PhaC_N PF07167.8 KPI36916.1 - 0.032 13.6 0.1 0.049 13.0 0.1 1.3 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus NUDIX PF00293.23 KPI36918.1 - 1.2e-18 67.0 0.2 1.5e-18 66.7 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_1 PF00583.19 KPI36919.1 - 7.1e-10 38.7 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI36919.1 - 1.7e-09 37.6 0.0 2.4e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SWI-SNF_Ssr4 PF08549.5 KPI36919.1 - 8.1 4.6 10.3 11 4.2 7.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SNF5 PF04855.7 KPI36920.1 - 2.8e-66 223.4 0.0 4.2e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 KPI36920.1 - 3.9e-06 26.1 1.1 8.1e-06 25.0 0.8 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF2439 PF10382.4 KPI36922.1 - 7.6e-14 51.6 0.1 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) DUF2017 PF09438.5 KPI36922.1 - 0.038 13.5 1.0 0.086 12.4 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) HET PF06985.6 KPI36923.1 - 1.3e-25 90.1 0.3 2.8e-25 89.0 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ketoacyl-synt_C PF02801.17 KPI36925.1 - 0.1 12.4 0.2 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Exo_endo_phos PF03372.18 KPI36926.1 - 4.4e-19 69.3 0.1 8.3e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lantibiotic_a PF14867.1 KPI36926.1 - 0.019 14.2 0.6 0.044 13.0 0.4 1.6 1 0 0 1 1 1 0 Lantibiotic alpha DUF3805 PF12712.2 KPI36926.1 - 0.073 12.8 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3805) Peptidase_S64 PF08192.6 KPI36926.1 - 1.9 6.6 14.5 3.1 6.0 10.1 1.2 1 0 0 1 1 1 0 Peptidase family S64 Cupin_2 PF07883.6 KPI36927.1 - 1.1e-10 40.8 1.0 2.2e-10 39.8 0.7 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KPI36927.1 - 6.9e-05 22.5 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain EutQ PF06249.7 KPI36927.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ MannoseP_isomer PF01050.13 KPI36927.1 - 0.11 12.1 0.2 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Bromodomain PF00439.20 KPI36928.1 - 5.4e-17 61.4 0.0 1.2e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 KPI36928.1 - 6.5e-17 61.4 4.8 6.5e-17 61.4 3.3 2.6 2 1 1 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex Helicase_C PF00271.26 KPI36928.1 - 1.6e-16 59.9 0.0 3.6e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KPI36928.1 - 2.1e-15 56.2 0.3 3.2e-15 55.7 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 KPI36928.1 - 9.8e-06 24.5 0.0 2.5e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 MOZART1 PF12554.3 KPI36930.1 - 4.1e-22 77.3 1.6 5.1e-22 77.0 1.1 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SRP54_N PF02881.14 KPI36930.1 - 0.049 13.7 0.1 0.13 12.4 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, helical bundle domain Clp_N PF02861.15 KPI36930.1 - 0.094 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Clp amino terminal domain SRP-alpha_N PF04086.8 KPI36931.1 - 7.6e-66 222.3 0.0 1.1e-65 221.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 KPI36931.1 - 1.6e-50 171.2 0.4 3.6e-50 170.1 0.3 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ArgK PF03308.11 KPI36931.1 - 2.8e-07 29.5 0.0 5.3e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 KPI36931.1 - 2.7e-06 26.9 1.2 8.9e-06 25.2 0.8 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 KPI36931.1 - 0.00033 20.6 0.3 0.00096 19.2 0.0 1.9 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.1 KPI36931.1 - 0.0063 16.1 0.1 0.046 13.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KPI36931.1 - 0.0094 15.4 0.3 0.034 13.5 0.1 2.0 2 1 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 KPI36931.1 - 0.018 14.4 0.0 0.051 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KPI36931.1 - 0.018 14.9 0.1 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase APS_kinase PF01583.15 KPI36931.1 - 0.022 14.4 0.0 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase MobB PF03205.9 KPI36931.1 - 0.023 14.4 0.2 0.063 12.9 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KPI36931.1 - 0.052 13.8 0.1 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.1 KPI36931.1 - 0.067 13.3 0.1 0.24 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.10 KPI36931.1 - 0.098 11.6 0.1 6.7 5.6 0.0 2.4 1 1 1 2 2 2 0 Anion-transporting ATPase Tad PF13400.1 KPI36932.1 - 0.52 10.3 7.8 0.92 9.5 5.4 1.4 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Lactamase_B PF00753.22 KPI36933.1 - 2.6e-08 33.7 0.0 5.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI36933.1 - 0.044 13.3 0.0 0.077 12.5 0.0 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DUF3425 PF11905.3 KPI36934.1 - 3.8e-08 33.3 0.1 8.3e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KPI36934.1 - 0.0021 17.9 2.1 0.0053 16.6 1.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor BAR PF03114.13 KPI36935.1 - 1.7e-48 165.1 11.5 2e-48 164.9 8.0 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 KPI36935.1 - 2.1e-06 26.8 8.0 3.4e-06 26.2 5.6 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Mso1_Sec1_bdg PF14475.1 KPI36937.1 - 5e-11 41.8 0.1 9.2e-11 40.9 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ammonium_transp PF00909.16 KPI36938.1 - 1.6e-56 191.5 25.1 8e-45 152.9 13.7 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family Sulfatase PF00884.18 KPI36939.1 - 3e-63 213.8 1.2 3.6e-63 213.6 0.9 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KPI36939.1 - 0.00013 21.4 0.5 0.00034 20.0 0.4 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KPI36939.1 - 0.048 12.0 0.0 0.15 10.4 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF229) Pyr_redox_3 PF13738.1 KPI36940.1 - 6e-24 85.2 0.2 1.4e-23 83.9 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI36940.1 - 4.2e-14 51.6 0.9 1.1e-13 50.2 0.1 2.0 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KPI36940.1 - 1e-10 41.1 0.1 1.1e-08 34.4 0.1 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KPI36940.1 - 2.9e-09 36.8 0.0 1.5e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI36940.1 - 0.00012 22.0 0.0 0.00058 19.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI36940.1 - 0.0011 18.7 0.2 0.083 12.6 0.0 3.3 3 1 1 4 4 4 1 FAD-NAD(P)-binding Mqo PF06039.10 KPI36940.1 - 0.002 16.3 0.1 0.4 8.7 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) DAO PF01266.19 KPI36940.1 - 0.0064 15.4 0.0 2.7 6.8 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase DUF2617 PF10936.3 KPI36940.1 - 0.043 13.3 1.7 0.27 10.7 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF2617 WD40 PF00400.27 KPI36941.1 - 4.2e-09 35.9 2.1 0.00093 18.9 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Na_H_Exchanger PF00999.16 KPI36942.1 - 8.9e-68 228.5 37.4 1.1e-67 228.2 25.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Aldo_ket_red PF00248.16 KPI36943.1 - 4.2e-41 140.6 0.0 2.6e-33 115.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family GFA PF04828.9 KPI36944.1 - 2.6e-07 30.4 1.2 3.7e-07 30.0 0.8 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_23 PF13489.1 KPI36945.1 - 2.4e-08 33.8 0.0 3.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI36945.1 - 3.8e-08 33.6 0.0 7.3e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI36945.1 - 5.5e-08 32.5 0.0 1.3e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI36945.1 - 0.00013 22.5 0.0 0.00037 21.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI36945.1 - 0.00036 20.8 0.0 0.00064 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI36945.1 - 0.0041 17.5 0.0 0.0091 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KPI36945.1 - 0.0076 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI36945.1 - 0.054 12.5 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FR47 PF08445.5 KPI36946.1 - 0.0049 16.5 0.0 0.0094 15.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein DUF1777 PF08648.7 KPI36947.1 - 3.4e-23 82.2 5.3 3.4e-23 82.2 3.7 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) Collagen_bind PF05737.7 KPI36947.1 - 0.053 13.6 2.3 0.084 13.0 1.6 1.3 1 0 0 1 1 1 0 Collagen binding domain JAB PF01398.16 KPI36948.1 - 6.1e-08 32.4 0.0 1.6e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease bZIP_1 PF00170.16 KPI36949.1 - 6.5e-08 32.4 10.8 9.7e-08 31.8 7.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor IncA PF04156.9 KPI36949.1 - 0.04 13.5 1.7 0.049 13.2 1.2 1.3 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 KPI36949.1 - 0.067 12.6 3.9 0.1 12.0 2.7 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_Maf PF03131.12 KPI36949.1 - 0.46 10.7 13.8 0.97 9.7 9.6 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor GCN5L1 PF06320.8 KPI36949.1 - 1.3 8.8 5.5 1.8 8.3 3.8 1.2 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) bZIP_2 PF07716.10 KPI36949.1 - 2.4 8.0 21.4 5.8 6.8 2.3 2.4 1 1 1 2 2 2 0 Basic region leucine zipper ERG2_Sigma1R PF04622.7 KPI36950.1 - 4e-78 261.5 0.2 4.4e-78 261.4 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Fungal_trans PF04082.13 KPI36952.1 - 4.4e-10 38.8 1.0 1.4e-09 37.2 0.3 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KPI36955.1 - 2.1e-25 89.1 28.4 3.1e-25 88.6 19.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI36955.1 - 1.2e-20 73.5 23.9 1.7e-20 73.0 16.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter ESSS PF10183.4 KPI36955.1 - 0.1 12.9 2.7 0.19 12.1 0.8 2.2 2 1 1 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Amastin PF07344.6 KPI36955.1 - 0.22 11.1 6.9 0.16 11.5 0.8 2.4 2 0 0 2 2 2 0 Amastin surface glycoprotein RhodobacterPufX PF11511.3 KPI36955.1 - 0.63 9.4 6.9 2.9 7.3 0.1 3.2 2 0 0 2 2 2 0 Intrinsic membrane protein PufX WD40 PF00400.27 KPI36956.1 - 3.1e-47 156.8 16.9 6.1e-11 41.7 0.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KPI36956.1 - 9.8e-06 25.3 12.6 0.0055 16.4 0.8 4.0 2 1 0 4 4 4 2 Transcription factor IIIC subunit delta N-term YmzC PF14157.1 KPI36956.1 - 0.048 13.4 0.2 21 5.0 0.0 3.4 3 0 0 3 3 3 0 YmzC-like protein Ribosomal_L2_C PF03947.13 KPI36957.1 - 1.2e-36 125.4 3.9 1.2e-36 125.4 2.7 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KPI36957.1 - 1.6e-15 56.8 0.1 3.7e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PP2C PF00481.16 KPI36958.1 - 3e-82 275.8 0.4 5.4e-82 275.0 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 KPI36958.1 - 0.0002 20.8 0.0 0.00053 19.4 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C DCP1 PF06058.8 KPI36959.1 - 1.9e-14 53.7 0.0 2.8e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family GSH_synth_ATP PF03917.12 KPI36960.1 - 5.3e-87 291.8 0.0 5e-84 282.0 0.0 2.9 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KPI36960.1 - 6.1e-26 90.5 0.0 1e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Clr5 PF14420.1 KPI36961.1 - 1.4e-15 56.8 0.4 5.1e-15 55.1 0.3 2.0 1 0 0 1 1 1 1 Clr5 domain Proteasom_PSMB PF10508.4 KPI36962.1 - 0.04 12.2 0.0 0.05 11.8 0.0 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit E1-E2_ATPase PF00122.15 KPI36964.1 - 1e-11 44.3 0.0 1e-11 44.3 0.0 2.8 4 0 0 4 4 4 1 E1-E2 ATPase HAD PF12710.2 KPI36964.1 - 8e-11 42.4 0.1 4.2e-10 40.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KPI36964.1 - 1.9e-10 40.5 0.0 4.7e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KPI36964.1 - 6.4e-10 39.7 1.4 2.2e-08 34.7 1.0 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KPI36964.1 - 0.015 14.8 0.5 0.038 13.5 0.2 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 KPI36965.1 - 2.4e-28 98.8 26.6 4.2e-28 98.0 16.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily SecE PF00584.15 KPI36965.1 - 0.02 14.4 0.0 0.085 12.4 0.0 2.1 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex RRXRR PF14239.1 KPI36965.1 - 0.026 13.9 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 RRXRR protein ESSS PF10183.4 KPI36965.1 - 0.12 12.7 1.4 4.4 7.7 0.1 2.6 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) SSB PF00436.20 KPI36966.1 - 1.5e-17 63.3 0.0 1.8e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Zn_clus PF00172.13 KPI36967.1 - 7.5e-08 32.1 7.5 1.1e-07 31.5 5.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAD_2 PF13419.1 KPI36968.1 - 9e-17 61.8 0.0 1.2e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KPI36968.1 - 2.8e-07 30.1 0.0 5.5e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KPI36968.1 - 3.7e-05 24.2 0.1 0.0005 20.5 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase MSA-2c PF12238.3 KPI36968.1 - 0.11 12.1 7.7 0.11 12.2 4.3 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c AF-4 PF05110.8 KPI36968.1 - 0.23 9.3 8.0 0.29 8.9 5.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF2305 PF10230.4 KPI36969.1 - 7.2e-49 166.5 0.0 1.1e-47 162.7 0.0 2.3 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KPI36969.1 - 1.2e-05 25.3 2.0 4.8e-05 23.3 1.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 KPI36969.1 - 0.0035 16.6 0.0 0.0067 15.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 KPI36969.1 - 0.016 14.9 0.2 0.023 14.4 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3640 PF12342.3 KPI36969.1 - 0.13 11.7 1.5 0.34 10.4 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3640) DMPK_coil PF08826.5 KPI36971.1 - 0.0055 16.5 0.3 0.018 14.9 0.2 1.9 1 0 0 1 1 1 1 DMPK coiled coil domain like THOC7 PF05615.8 KPI36971.1 - 0.039 14.2 1.4 0.068 13.4 1.0 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 DUF972 PF06156.8 KPI36971.1 - 0.12 12.7 3.9 0.32 11.3 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) SEN1_N PF12726.2 KPI36972.1 - 2e-165 551.8 15.0 2.6e-165 551.4 10.4 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 KPI36972.1 - 1.5e-68 230.8 2.4 1.5e-68 230.8 1.7 2.7 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KPI36972.1 - 1.1e-60 204.4 0.0 2.5e-60 203.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KPI36972.1 - 2.7e-12 46.2 0.1 9.6e-12 44.4 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KPI36972.1 - 2.1e-09 37.2 0.6 1.3e-06 28.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KPI36972.1 - 1.4e-06 28.0 0.4 0.0037 16.8 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 KPI36972.1 - 6e-05 23.4 0.1 6e-05 23.4 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KPI36972.1 - 0.0015 18.0 0.0 0.0038 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KPI36972.1 - 0.0027 16.6 0.0 0.0057 15.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 KPI36972.1 - 0.057 12.9 0.1 0.16 11.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SNF2_N PF00176.18 KPI36973.1 - 6e-67 225.5 0.0 8.3e-67 225.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 KPI36973.1 - 1.2e-10 40.8 6.6 2.1e-10 40.0 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 KPI36973.1 - 1.6e-09 37.5 0.0 3.4e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KPI36973.1 - 1.1e-07 31.7 9.4 2e-07 30.8 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 KPI36973.1 - 8.5e-07 28.6 0.0 1.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 KPI36973.1 - 2.1e-06 27.4 9.1 4.3e-06 26.4 6.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KPI36973.1 - 4.2e-06 26.5 9.9 7.6e-06 25.7 6.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KPI36973.1 - 9.9e-06 25.1 9.3 2.3e-05 23.9 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KPI36973.1 - 7e-05 22.4 2.7 0.00016 21.2 1.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KPI36973.1 - 0.00074 19.1 9.0 0.0016 18.1 6.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 KPI36973.1 - 0.0013 18.2 7.2 0.0029 17.1 5.0 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain CHASE2 PF05226.6 KPI36973.1 - 0.056 12.6 3.2 0.1 11.8 2.2 1.3 1 0 0 1 1 1 0 CHASE2 domain Prok-RING_4 PF14447.1 KPI36973.1 - 0.13 11.8 8.2 1.1 8.9 5.6 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Ribosom_S12_S23 PF00164.20 KPI36974.1 - 5.6e-37 125.8 0.5 6.5e-37 125.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DAO PF01266.19 KPI36975.1 - 7.8e-46 156.6 0.0 9.6e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI36975.1 - 3.4e-05 23.7 0.4 3.4e-05 23.7 0.3 2.1 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Strep_67kDa_ant PF06100.6 KPI36975.1 - 0.015 13.7 0.0 0.026 12.8 0.0 1.4 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Pyr_redox_3 PF13738.1 KPI36975.1 - 0.12 12.4 0.0 7.8 6.4 0.0 2.3 1 1 2 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 KPI36976.1 - 1.4e-66 224.2 0.0 3.1e-66 223.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI36976.1 - 3.9e-49 167.0 0.0 1.5e-48 165.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KPI36976.1 - 3.6e-29 100.7 0.4 8.5e-29 99.5 0.1 1.8 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 KPI36976.1 - 2.3e-15 56.5 0.0 4.7e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KPI36976.1 - 2e-14 53.1 0.0 4.4e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 KPI36976.1 - 1.4e-06 27.4 0.0 0.00059 18.8 0.0 2.5 2 0 0 2 2 2 2 Kinase-like RA PF00788.18 KPI36976.1 - 0.029 14.8 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Kdo PF06293.9 KPI36976.1 - 0.064 12.3 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RecR PF02132.10 KPI36976.1 - 0.14 11.6 1.3 0.39 10.1 0.9 1.8 1 0 0 1 1 1 0 RecR protein Abhydrolase_6 PF12697.2 KPI36977.1 - 2.3e-21 76.7 0.0 6.7e-21 75.2 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI36977.1 - 1.5e-09 37.7 0.1 4.2e-09 36.3 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI36977.1 - 4e-09 36.3 0.1 0.00011 21.8 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold MFS_1 PF07690.11 KPI36978.1 - 2.7e-30 105.2 28.2 6.7e-16 57.9 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI36978.1 - 3.8e-05 22.2 20.4 0.031 12.6 2.6 3.1 2 2 1 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 KPI36978.1 - 8.5e-05 21.2 14.8 0.00049 18.7 10.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 KPI36978.1 - 0.0014 18.3 4.9 0.2 11.4 0.2 3.3 3 0 0 3 3 3 2 MFS_1 like family OATP PF03137.15 KPI36978.1 - 0.88 7.5 5.9 1.3 7.0 0.9 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Bac_luciferase PF00296.15 KPI36979.1 - 2.3e-61 207.6 0.6 3.3e-61 207.0 0.4 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase He_PIG PF05345.7 KPI36981.1 - 1.6e-11 44.0 14.7 0.00082 19.3 0.1 5.5 4 1 1 5 5 5 3 Putative Ig domain Rifin_STEVOR PF02009.11 KPI36981.1 - 2.7e-06 27.2 0.1 4.7e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Rifin/stevor family TMEM154 PF15102.1 KPI36981.1 - 1.6e-05 24.6 0.9 4.3e-05 23.2 0.1 2.2 2 0 0 2 2 2 1 TMEM154 protein family gpUL132 PF11359.3 KPI36981.1 - 0.0003 20.2 1.4 0.0003 20.2 0.9 2.7 3 0 0 3 3 2 1 Glycoprotein UL132 DUF4448 PF14610.1 KPI36981.1 - 0.0021 17.5 0.0 0.0063 16.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF912 PF06024.7 KPI36981.1 - 0.0052 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Adeno_E3_CR2 PF02439.10 KPI36981.1 - 0.055 13.0 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2207 PF09972.4 KPI36981.1 - 0.1 11.1 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3609 PF12259.3 KPI36981.1 - 0.12 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) NfeD PF01957.13 KPI36981.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Herpes_gE PF02480.11 KPI36981.1 - 0.15 10.3 0.0 0.26 9.5 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E YajC PF02699.10 KPI36981.1 - 0.31 10.7 0.1 0.64 9.7 0.1 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit PMP1_2 PF08114.6 KPI36981.1 - 0.4 10.2 1.9 0.83 9.1 1.3 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Amnionless PF14828.1 KPI36981.1 - 0.56 8.6 0.0 0.87 8.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless Pkinase PF00069.20 KPI36982.1 - 5.5e-59 199.4 0.0 1.4e-53 181.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KPI36982.1 - 2.1e-27 95.8 0.0 1.9e-24 86.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 KPI36982.1 - 1.5e-08 34.5 0.0 3.2e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KPI36982.1 - 0.00022 20.3 0.0 0.00052 19.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KPI36982.1 - 0.00067 18.7 0.0 0.0023 17.0 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KPI36982.1 - 0.0067 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 KPI36982.1 - 0.037 13.7 0.6 0.098 12.3 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Fucokinase PF07959.7 KPI36982.1 - 0.065 11.7 0.0 0.13 10.8 0.0 1.4 1 0 0 1 1 1 0 L-fucokinase Methyltransf_18 PF12847.2 KPI36983.1 - 3.4e-13 50.1 0.0 5.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI36983.1 - 5e-11 42.4 0.0 1.3e-10 41.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI36983.1 - 0.0017 18.6 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI36983.1 - 0.0027 17.4 0.0 0.0071 16.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI36983.1 - 0.0028 17.6 0.0 0.0054 16.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KPI36983.1 - 0.0032 17.1 0.0 0.0051 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI36983.1 - 0.0049 17.3 0.0 0.012 16.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI36983.1 - 0.0089 16.4 0.0 0.059 13.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.11 KPI36983.1 - 0.028 13.2 0.0 0.11 11.3 0.0 1.8 2 0 0 2 2 2 0 mRNA capping enzyme adh_short PF00106.20 KPI36985.1 - 2.2e-16 60.2 0.5 5.1e-16 59.0 0.3 1.7 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI36985.1 - 1.5e-07 31.4 0.0 2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI36985.1 - 0.00091 18.9 0.2 0.0016 18.1 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI36985.1 - 0.027 14.4 0.2 0.075 13.0 0.1 1.8 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KPI36985.1 - 0.086 12.6 1.9 0.13 12.0 0.0 2.2 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.11 KPI36986.1 - 8.2e-27 93.5 0.0 1.4e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KPI36986.1 - 2.8e-19 69.3 0.0 5.3e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.6 KPI36986.1 - 1.7e-17 63.3 1.8 4e-17 62.1 1.2 1.7 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like PfkB PF00294.19 KPI36987.1 - 1.5e-64 218.0 0.0 1.8e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KPI36987.1 - 0.021 14.0 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Herpes_gE PF02480.11 KPI36988.1 - 0.008 14.4 0.0 0.01 14.1 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF4448 PF14610.1 KPI36988.1 - 0.015 14.7 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1191 PF06697.7 KPI36988.1 - 0.027 13.3 0.0 0.032 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF202 PF02656.10 KPI36988.1 - 0.027 14.6 1.5 0.048 13.8 1.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF202) SCIMP PF15050.1 KPI36988.1 - 0.034 14.0 0.1 0.083 12.7 0.0 1.6 1 1 1 2 2 2 0 SCIMP protein DUF1056 PF06341.6 KPI36988.1 - 0.049 13.6 0.1 0.071 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) Glycophorin_A PF01102.13 KPI36988.1 - 0.079 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycophorin A Ndc1_Nup PF09531.5 KPI36990.1 - 0.039 12.3 4.6 0.044 12.2 3.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2217 PF10265.4 KPI36990.1 - 0.26 10.0 2.3 0.31 9.7 1.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Glyco_transf_8 PF01501.15 KPI36991.1 - 1.5e-25 89.9 0.0 2.3e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KPI36991.1 - 0.033 13.5 0.0 0.078 12.3 0.0 1.6 1 1 0 1 1 1 0 Mannosyltransferase putative adh_short PF00106.20 KPI36992.1 - 5.7e-16 58.8 0.2 1.1e-13 51.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KPI36992.1 - 8e-09 35.6 0.0 0.0027 17.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KPI36992.1 - 2.7e-06 26.9 0.0 5e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KPI36992.1 - 0.0063 15.4 0.0 0.018 13.9 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein Transaldolase PF00923.14 KPI36993.1 - 9.6e-97 323.5 0.1 1.1e-96 323.3 0.1 1.0 1 0 0 1 1 1 1 Transaldolase SecD-TM1 PF13721.1 KPI36993.1 - 0.0056 16.9 0.2 1.3 9.2 0.0 2.3 2 0 0 2 2 2 2 SecD export protein N-terminal TM region Amidoligase_2 PF12224.3 KPI36994.1 - 9.2e-09 35.2 1.1 0.079 12.5 0.0 3.3 3 0 0 3 3 3 3 Putative amidoligase enzyme DUF3449 PF11931.3 KPI36994.1 - 1.6 8.2 9.6 1.5 8.2 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) MFS_1 PF07690.11 KPI36995.1 - 3.8e-21 75.1 58.2 2.5e-11 42.8 13.7 3.9 2 2 2 4 4 4 3 Major Facilitator Superfamily ABC_membrane PF00664.18 KPI36996.1 - 7.8e-51 173.0 17.0 8e-28 97.6 1.8 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 KPI36996.1 - 7e-40 136.4 0.1 1.4e-21 77.2 0.0 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KPI36996.1 - 3.5e-08 32.9 0.6 0.0014 17.8 0.0 3.5 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KPI36996.1 - 3.6e-07 30.4 0.3 0.045 13.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KPI36996.1 - 0.00012 22.4 0.0 0.00035 20.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KPI36996.1 - 0.002 17.2 0.0 0.0044 16.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin T2SE PF00437.15 KPI36996.1 - 0.015 14.2 0.0 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 KPI36996.1 - 0.027 13.8 0.0 0.075 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KPI36996.1 - 0.1 11.7 0.1 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SNF2_N PF00176.18 KPI36997.1 - 6.3e-47 159.8 0.0 1.1e-46 158.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KPI36997.1 - 8.9e-09 35.0 0.0 2.6e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI36997.1 - 1.1e-07 31.8 0.0 7.8e-07 29.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SAM_2 PF07647.12 KPI36997.1 - 0.00053 19.7 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Bac_luciferase PF00296.15 KPI36998.1 - 4.2e-49 167.3 0.0 7.3e-49 166.5 0.0 1.3 1 1 0 1 1 1 1 Luciferase-like monooxygenase RNA_pol_I_A49 PF06870.7 KPI36999.1 - 2.8e-38 131.4 0.0 4.7e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DUF1485 PF07364.7 KPI37000.1 - 3.4e-71 239.8 0.1 5e-71 239.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1485) MlrC_C PF07171.7 KPI37000.1 - 1.5e-42 145.1 0.2 2.9e-42 144.1 0.1 1.5 1 0 0 1 1 1 1 MlrC C-terminus DUF866 PF05907.8 KPI37001.1 - 6e-48 162.3 0.1 6.5e-48 162.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) PHD PF00628.24 KPI37001.1 - 0.027 14.1 1.4 0.057 13.1 0.9 1.6 1 0 0 1 1 1 0 PHD-finger Cas_CXXC_CXXC PF09706.5 KPI37001.1 - 0.13 12.4 0.9 0.21 11.7 0.6 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) DUF3716 PF12511.3 KPI37001.1 - 0.5 10.0 6.2 1 9.0 4.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) CH PF00307.26 KPI37002.1 - 9e-37 125.4 0.0 8.8e-19 67.5 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KPI37002.1 - 1.2e-26 92.4 0.5 5.3e-26 90.3 0.0 2.4 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 KPI37002.1 - 8.8e-12 44.5 0.2 6e-08 32.2 0.0 3.3 3 1 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 KPI37002.1 - 6.7e-05 22.4 0.1 0.00038 20.1 0.0 2.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 KPI37002.1 - 0.00057 19.0 0.1 0.0022 17.1 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KPI37002.1 - 0.002 17.7 0.0 0.0055 16.2 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair DUF1943 PF09172.6 KPI37002.1 - 0.012 14.5 0.3 0.021 13.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) EF-hand_7 PF13499.1 KPI37002.1 - 0.015 15.4 1.0 0.18 11.9 0.1 3.0 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.1 KPI37002.1 - 0.039 13.3 0.1 0.1 11.9 0.0 1.8 1 0 0 1 1 1 0 EF hand Spectrin PF00435.16 KPI37002.1 - 0.13 12.5 7.1 0.99 9.7 0.1 2.8 2 0 0 2 2 2 0 Spectrin repeat YrbL-PhoP_reg PF10707.4 KPI37003.1 - 0.021 14.1 0.0 0.033 13.5 0.0 1.3 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Abhydrolase_6 PF12697.2 KPI37006.1 - 3.9e-28 98.8 2.4 1.7e-27 96.8 1.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI37006.1 - 5.5e-09 35.9 0.0 3.1e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI37006.1 - 4.1e-08 33.0 0.2 1.8e-07 30.9 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KPI37006.1 - 1.3e-06 28.2 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 KPI37006.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase SH3_9 PF14604.1 KPI37007.1 - 7.7e-14 51.0 0.3 2.2e-13 49.5 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KPI37007.1 - 5.3e-13 48.1 0.2 9.8e-13 47.2 0.2 1.5 1 0 0 1 1 1 1 SH3 domain BAR PF03114.13 KPI37007.1 - 1.3e-09 37.8 5.7 2e-09 37.2 1.2 2.1 2 0 0 2 2 2 1 BAR domain SH3_2 PF07653.12 KPI37007.1 - 1.3e-08 34.1 0.0 3.1e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain E2R135 PF11570.3 KPI37007.1 - 0.0006 19.9 6.3 0.0015 18.6 2.8 2.3 2 0 0 2 2 2 1 Coiled-coil receptor-binding R-domain of colicin E2 NUDIX PF00293.23 KPI37008.1 - 3.8e-07 29.8 0.0 7.1e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain SUR7 PF06687.7 KPI37009.1 - 1e-29 103.6 1.3 1.4e-29 103.1 0.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family IncA PF04156.9 KPI37009.1 - 0.37 10.3 6.8 23 4.5 0.0 2.9 3 0 0 3 3 3 0 IncA protein Fig1 PF12351.3 KPI37009.1 - 0.78 9.5 14.8 0.19 11.5 6.9 2.1 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 EcsB PF05975.7 KPI37009.1 - 6.8 5.0 9.2 0.13 10.7 0.4 2.0 2 1 0 2 2 2 0 Bacterial ABC transporter protein EcsB MFS_1 PF07690.11 KPI37010.1 - 4.7e-27 94.6 25.3 7.7e-27 93.9 17.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily V_ATPase_I PF01496.14 KPI37010.1 - 0.15 9.8 4.6 0.23 9.2 3.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rick_17kDa_Anti PF05433.10 KPI37010.1 - 3.5 7.3 7.8 0.11 12.1 0.9 1.9 2 0 0 2 2 2 0 Glycine zipper 2TM domain RasGAP PF00616.14 KPI37011.1 - 0.05 13.2 0.1 3.9 7.0 0.0 2.4 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase UQ_con PF00179.21 KPI37012.1 - 4.4e-41 139.5 0.1 6.5e-41 139.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KPI37012.1 - 0.045 13.6 0.5 0.14 12.0 0.3 1.8 1 1 0 1 1 1 0 RWD domain AA_permease_2 PF13520.1 KPI37013.1 - 2.8e-47 161.2 41.0 5.5e-45 153.6 19.2 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 KPI37013.1 - 9.6e-20 70.3 15.0 9.6e-20 70.3 10.4 3.0 3 0 0 3 3 3 1 Amino acid permease NADHdeh_related PF10125.4 KPI37013.1 - 0.0021 17.2 2.9 0.0051 15.9 2.0 1.6 1 0 0 1 1 1 1 NADH dehydrogenase I, subunit N related protein DUF4097 PF13349.1 KPI37013.1 - 0.05 13.1 0.2 0.13 11.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) TRP PF06011.7 KPI37014.1 - 2.3e-96 323.0 15.5 3.1e-96 322.6 10.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KPI37014.1 - 1.9e-29 102.5 0.0 3.3e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 ML-like domain Myb_DNA-bind_2 PF08914.6 KPI37014.1 - 0.028 14.2 0.4 0.028 14.2 0.3 1.7 2 0 0 2 2 2 0 Rap1 Myb domain Mito_fiss_reg PF05308.6 KPI37014.1 - 3.7 6.8 12.1 1.8 7.8 6.2 1.9 1 1 1 2 2 2 0 Mitochondrial fission regulator Mito_carr PF00153.22 KPI37017.1 - 4e-45 151.4 2.9 1.1e-19 69.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_lectin PF07938.7 KPI37020.1 - 3.5e-12 46.2 0.7 1.9e-05 24.1 0.1 2.0 1 1 1 2 2 2 2 Fungal fucose-specific lectin VCBS PF13517.1 KPI37020.1 - 0.1 13.0 1.6 4.6 7.6 0.2 2.2 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella ABC_tran PF00005.22 KPI37021.1 - 2.1e-36 125.2 0.0 4.4e-36 124.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KPI37021.1 - 4.7e-33 114.7 15.7 6.3e-33 114.3 10.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KPI37021.1 - 6.1e-09 36.2 0.1 0.0013 18.8 0.0 3.0 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 KPI37021.1 - 2.4e-06 26.9 0.0 0.00047 19.4 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KPI37021.1 - 7.9e-06 25.9 0.0 4.4e-05 23.5 0.0 2.3 3 0 0 3 3 2 1 AAA ATPase domain AAA_14 PF13173.1 KPI37021.1 - 5.6e-05 23.0 0.1 0.0017 18.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KPI37021.1 - 0.00016 21.8 0.1 0.0015 18.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KPI37021.1 - 0.00023 21.9 0.0 0.00051 20.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KPI37021.1 - 0.00037 19.7 0.0 0.00075 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 KPI37021.1 - 0.0015 18.0 0.0 0.0036 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA-like domain ABC_ATPase PF09818.4 KPI37021.1 - 0.0025 16.4 0.0 0.18 10.3 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.1 KPI37021.1 - 0.003 17.0 0.1 0.0085 15.5 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KPI37021.1 - 0.0031 16.6 0.0 0.008 15.2 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KPI37021.1 - 0.0035 17.6 0.0 0.023 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KPI37021.1 - 0.0051 16.7 0.0 0.032 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KPI37021.1 - 0.0068 16.6 0.0 0.058 13.5 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KPI37021.1 - 0.013 15.3 0.1 0.056 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KPI37021.1 - 0.013 15.1 0.1 0.05 13.3 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KPI37021.1 - 0.016 15.1 0.0 0.052 13.5 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.9 KPI37021.1 - 0.043 13.5 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KPI37021.1 - 0.046 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KPI37021.1 - 0.055 13.7 0.3 0.28 11.4 0.0 2.2 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 KPI37021.1 - 0.085 12.5 0.1 0.28 10.8 0.0 1.9 2 0 0 2 2 1 0 NACHT domain T2SE PF00437.15 KPI37021.1 - 0.095 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.17 KPI37021.1 - 0.096 11.5 0.1 0.3 9.9 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 KPI37021.1 - 0.17 11.4 2.9 0.49 9.9 0.1 2.7 3 1 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 KPI37021.1 - 0.26 11.2 1.5 1.1 9.2 0.1 2.5 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit HET PF06985.6 KPI37022.1 - 1.2e-18 67.5 11.2 1.4e-16 60.9 2.1 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA_17 PF13207.1 KPI37023.1 - 2.8e-05 24.9 0.5 7e-05 23.6 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 KPI37023.1 - 0.00046 20.4 0.0 0.0015 18.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA PF00004.24 KPI37023.1 - 0.00046 20.3 0.0 0.0012 19.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KPI37023.1 - 0.00053 18.9 0.0 0.0012 17.7 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.7 KPI37023.1 - 0.00061 19.4 0.0 0.0018 17.9 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KPI37023.1 - 0.00071 19.7 0.1 0.0021 18.1 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KPI37023.1 - 0.0011 18.7 0.0 0.0066 16.1 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 KPI37023.1 - 0.0012 18.7 0.8 0.0063 16.3 0.0 2.5 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 KPI37023.1 - 0.0015 18.5 0.1 0.0061 16.5 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 KPI37023.1 - 0.0026 16.8 0.0 0.0056 15.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin PRK PF00485.13 KPI37023.1 - 0.0061 16.1 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family RuvB_N PF05496.7 KPI37023.1 - 0.0077 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 KPI37023.1 - 0.012 14.5 0.0 0.029 13.2 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.9 KPI37023.1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 KPI37023.1 - 0.021 14.3 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KTI12 PF08433.5 KPI37023.1 - 0.022 13.9 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_25 PF13481.1 KPI37023.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 KPI37023.1 - 0.026 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF2075 PF09848.4 KPI37023.1 - 0.038 12.9 0.0 0.066 12.1 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 KPI37023.1 - 0.04 13.3 0.1 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 KPI37023.1 - 0.046 13.2 0.0 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KPI37023.1 - 0.047 13.2 0.0 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 KPI37023.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KPI37023.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NTPase DnaB_C PF03796.10 KPI37023.1 - 0.092 11.6 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_28 PF13521.1 KPI37023.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain IMPDH PF00478.20 KPI37024.1 - 3.3e-130 434.0 1.4 4.3e-130 433.6 1.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KPI37024.1 - 3.5e-19 68.3 0.0 1.8e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 KPI37024.1 - 1.6e-06 27.1 0.8 2.8e-06 26.4 0.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 KPI37024.1 - 2e-06 27.2 8.5 0.012 14.7 5.8 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 KPI37024.1 - 9.6e-05 21.7 0.7 0.00021 20.6 0.5 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein Cache_3 PF14827.1 KPI37024.1 - 0.017 14.9 0.3 0.053 13.4 0.0 1.9 2 0 0 2 2 2 0 Sensory domain of two-component sensor kinase PK PF00224.16 KPI37024.1 - 0.037 12.6 0.0 0.065 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain ThiG PF05690.9 KPI37024.1 - 0.039 13.0 1.1 0.071 12.1 0.4 1.6 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG DUF1273 PF06908.6 KPI37024.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) Aldolase PF01081.14 KPI37024.1 - 0.066 12.3 0.3 0.32 10.1 0.0 2.1 2 0 0 2 2 2 0 KDPG and KHG aldolase Glyoxalase_2 PF12681.2 KPI37025.1 - 1.2e-09 38.7 0.2 0.00042 20.8 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 KPI37025.1 - 2.8e-07 30.5 1.1 1.5e-06 28.2 0.1 2.4 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HpcH_HpaI PF03328.9 KPI37026.1 - 2.3e-30 105.1 0.0 3.8e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.13 KPI37026.1 - 0.0014 17.5 0.7 0.013 14.3 0.1 2.5 2 2 0 2 2 2 1 PEP-utilising enzyme, TIM barrel domain Nfu_N PF08712.6 KPI37026.1 - 0.023 14.2 0.0 0.081 12.5 0.0 1.9 2 0 0 2 2 2 0 Scaffold protein Nfu/NifU N terminal p450 PF00067.17 KPI37028.1 - 1.2e-58 198.7 0.0 1.6e-58 198.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Oxidored_FMN PF00724.15 KPI37029.1 - 4.9e-47 160.5 0.0 6.4e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 KPI37029.1 - 0.031 13.5 0.1 0.89 8.7 0.0 2.3 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel FMO-like PF00743.14 KPI37030.1 - 9.9e-35 119.7 0.0 1.2e-25 89.7 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KPI37030.1 - 1.7e-21 77.2 0.0 3.9e-21 76.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI37030.1 - 2.6e-12 46.8 0.0 1.7e-10 40.8 0.0 3.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KPI37030.1 - 2.3e-10 39.9 0.1 2.8e-08 33.0 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KPI37030.1 - 1.8e-09 37.8 0.0 1.9e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI37030.1 - 3.8e-06 26.1 0.0 0.032 13.3 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 KPI37030.1 - 8.8e-06 25.6 0.0 2.5e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI37030.1 - 1.1e-05 24.4 0.0 1 8.2 0.0 3.3 3 1 0 3 3 3 3 FAD dependent oxidoreductase HI0933_like PF03486.9 KPI37030.1 - 0.012 14.0 0.0 3 6.2 0.0 2.4 2 1 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 KPI37030.1 - 0.024 15.0 0.0 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 KPI37030.1 - 0.082 11.0 0.0 0.13 10.3 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Raptor_N PF14538.1 KPI37031.1 - 2.2e-61 206.2 0.0 5.6e-61 204.8 0.0 1.8 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KPI37031.1 - 1.4e-05 24.7 2.0 0.23 11.3 0.0 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat HEAT PF02985.17 KPI37031.1 - 0.0096 15.9 0.3 2 8.7 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat Peptidase_C14 PF00656.17 KPI37031.1 - 0.034 13.8 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Caspase domain Fungal_trans PF04082.13 KPI37033.1 - 9.9e-21 73.7 0.1 1.7e-20 73.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI37033.1 - 2.1e-06 27.5 4.9 4e-06 26.6 3.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.19 KPI37035.1 - 1.4e-05 25.0 0.4 2.5e-05 24.2 0.3 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI37035.1 - 0.00017 21.6 0.0 0.00036 20.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FAD_binding_3 PF01494.14 KPI37036.1 - 8.9e-18 64.4 1.1 1.2e-17 64.0 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KPI37036.1 - 8.3e-10 38.0 1.7 0.00015 20.7 0.6 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI37036.1 - 2.8e-07 30.5 0.3 3.7e-06 26.9 0.8 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI37036.1 - 5.9e-07 29.4 0.1 1.2e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KPI37036.1 - 3.8e-05 24.0 1.3 0.00022 21.5 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI37036.1 - 0.00032 19.6 1.6 0.00071 18.5 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KPI37036.1 - 0.0011 17.4 2.7 0.017 13.5 0.2 2.5 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 KPI37036.1 - 0.0029 16.7 0.3 1.7 7.5 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 KPI37036.1 - 0.0031 17.1 1.3 0.0053 16.3 0.3 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain MscS_porin PF12795.2 KPI37036.1 - 0.012 14.9 11.5 0.026 13.8 8.0 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Trp_halogenase PF04820.9 KPI37036.1 - 0.013 14.2 2.1 0.28 9.7 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 KPI37036.1 - 0.013 15.5 0.9 0.013 15.5 0.6 2.4 2 1 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI37036.1 - 0.015 15.1 0.9 0.53 10.0 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 KPI37036.1 - 0.028 13.5 0.2 0.066 12.2 0.1 1.6 1 0 0 1 1 1 0 Thi4 family NAD_binding_2 PF03446.10 KPI37036.1 - 0.048 13.5 1.5 0.097 12.5 0.0 2.2 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase Lycopene_cycl PF05834.7 KPI37036.1 - 0.057 12.3 0.3 7.3 5.4 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 KPI37036.1 - 0.063 12.1 8.6 0.011 14.6 1.9 2.3 2 1 0 2 2 2 0 Glucose inhibited division protein A Fez1 PF06818.10 KPI37036.1 - 0.084 12.8 2.4 0.14 12.1 1.7 1.3 1 0 0 1 1 1 0 Fez1 UDPG_MGDP_dh_N PF03721.9 KPI37036.1 - 0.28 10.5 3.1 0.34 10.2 0.0 2.5 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ATP-synt_DE PF00401.15 KPI37036.1 - 2.4 8.1 6.6 6 6.8 0.7 2.6 1 1 1 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain PAT1 PF09770.4 KPI37036.1 - 3.9 5.6 20.9 5.6 5.0 14.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAD_binding_4 PF01565.18 KPI37037.1 - 1.2e-21 76.6 0.1 2.9e-21 75.4 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KPI37037.1 - 0.001 18.9 0.1 0.0027 17.5 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like HAMP PF00672.20 KPI37038.1 - 2.2e-46 155.8 23.7 2.5e-09 37.1 0.1 7.9 7 1 1 8 8 8 6 HAMP domain Response_reg PF00072.19 KPI37038.1 - 1.5e-30 105.4 2.5 2.9e-26 91.6 0.3 2.8 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.21 KPI37038.1 - 5.5e-29 100.1 0.8 3.8e-28 97.4 0.1 2.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KPI37038.1 - 6.7e-17 61.2 0.2 6.7e-17 61.2 0.1 4.5 6 0 0 6 6 6 1 His Kinase A (phospho-acceptor) domain Lzipper-MIP1 PF14389.1 KPI37038.1 - 0.0053 16.8 6.4 1.1 9.3 0.7 4.8 4 0 0 4 4 4 2 Leucine-zipper of ternary complex factor MIP1 NAAA-beta PF15508.1 KPI37038.1 - 0.006 16.9 4.7 1.9 8.8 0.1 6.0 5 2 2 7 7 7 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase AAA_13 PF13166.1 KPI37038.1 - 0.054 11.9 24.1 0.22 9.9 1.1 4.0 1 1 4 5 5 5 0 AAA domain TSC22 PF01166.13 KPI37038.1 - 0.09 12.7 3.6 11 6.0 0.0 4.9 5 0 0 5 5 5 0 TSC-22/dip/bun family Prominin PF05478.6 KPI37038.1 - 1 6.7 21.1 1.6 6.2 0.8 3.9 3 1 0 3 3 3 0 Prominin AIM24 PF01987.12 KPI37039.1 - 1.4e-34 119.4 0.0 2.2e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 KPI37039.1 - 0.8 10.1 10.2 0.23 11.9 3.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4402) Pmp3 PF01679.12 KPI37040.1 - 1.7e-23 82.0 3.6 2e-23 81.8 2.5 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1056 PF06341.6 KPI37040.1 - 0.013 15.5 0.4 0.017 15.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) F-box PF00646.28 KPI37041.1 - 5.6e-05 22.6 0.0 0.00032 20.2 0.0 2.3 2 0 0 2 2 2 1 F-box domain TPR_2 PF07719.12 KPI37041.1 - 0.00033 20.3 0.1 1.5 8.8 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KPI37041.1 - 0.00068 19.2 0.1 0.55 9.9 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 KPI37041.1 - 0.0017 18.9 0.4 0.076 13.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat F-box-like PF12937.2 KPI37041.1 - 0.013 15.1 0.0 0.032 13.9 0.0 1.7 1 0 0 1 1 1 0 F-box-like TPR_14 PF13428.1 KPI37041.1 - 0.015 15.8 2.9 4.1 8.3 0.1 4.0 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KPI37041.1 - 0.047 14.0 1.6 0.79 10.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 KPI37042.1 - 1.1e-22 81.0 0.1 1.6e-22 80.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI37042.1 - 4.3e-08 33.0 0.0 1.3e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI37042.1 - 8.8e-08 31.9 0.1 0.003 17.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KPI37042.1 - 0.0014 18.4 0.7 0.0033 17.2 0.1 2.0 2 1 0 2 2 2 1 Putative lysophospholipase NUDIX PF00293.23 KPI37043.1 - 3.5e-08 33.1 0.0 2.3e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 NUDIX domain FAD_binding_3 PF01494.14 KPI37044.1 - 5.1e-68 229.7 0.0 6.7e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KPI37044.1 - 8.3e-07 28.4 0.0 0.00014 21.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI37044.1 - 9.7e-07 27.9 0.0 9.2e-06 24.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KPI37044.1 - 1.3e-06 27.5 0.0 9.1e-05 21.5 0.0 2.7 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI37044.1 - 7.1e-06 25.9 0.0 4.1e-05 23.5 0.0 2.4 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KPI37044.1 - 9.7e-06 24.2 0.0 1.9e-05 23.3 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KPI37044.1 - 4.2e-05 22.7 0.0 7.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 KPI37044.1 - 4.9e-05 22.4 0.0 0.045 12.6 0.0 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KPI37044.1 - 6.2e-05 22.9 0.0 0.00027 20.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI37044.1 - 0.00016 20.6 0.0 0.00026 19.9 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KPI37044.1 - 0.00036 20.6 0.0 0.0014 18.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI37044.1 - 0.051 13.3 0.6 0.66 9.7 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 KPI37044.1 - 0.1 13.0 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KPI37044.1 - 0.15 10.6 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.13 KPI37044.1 - 0.21 11.6 0.0 0.46 10.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans PF04082.13 KPI37046.1 - 7.2e-16 57.8 0.0 1.1e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRP7 PF12923.2 KPI37048.1 - 4.3e-28 97.9 8.0 7.8e-28 97.1 5.5 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_6 PF14259.1 KPI37048.1 - 0.0081 16.1 0.1 0.77 9.7 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1180 PF06679.7 KPI37049.1 - 0.057 13.3 1.5 0.14 12.0 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) HATPase_c PF02518.21 KPI37050.1 - 3.3e-27 94.3 0.1 1.3e-26 92.4 0.1 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KPI37050.1 - 1.9e-13 50.3 0.0 3.8e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KPI37050.1 - 5.2e-13 48.7 0.0 1.1e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 KPI37050.1 - 0.00024 21.1 0.4 0.00024 21.1 0.3 2.9 2 1 0 2 2 2 1 HAMP domain ADH_N PF08240.7 KPI37051.1 - 4.9e-26 90.6 0.1 1.2e-25 89.3 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI37051.1 - 9.2e-20 70.5 0.7 1.4e-19 69.8 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI37051.1 - 3.3e-11 44.1 0.0 6.7e-11 43.1 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KPI37051.1 - 0.0031 17.0 0.1 0.0048 16.4 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Saccharop_dh PF03435.13 KPI37051.1 - 0.0076 15.2 0.1 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KPI37051.1 - 0.041 13.9 0.1 0.068 13.2 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KPI37051.1 - 0.36 10.6 1.9 5.6 6.7 1.6 2.1 1 1 1 2 2 2 0 ThiF family LtrA PF06772.6 KPI37052.1 - 1.1e-15 57.3 19.4 2.6e-08 33.1 3.3 2.6 3 0 0 3 3 3 2 Bacterial low temperature requirement A protein (LtrA) Glyco_hydro_88 PF07470.8 KPI37053.1 - 1.2e-20 73.8 0.0 2.1e-20 73.0 0.0 1.3 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Rtt106 PF08512.7 KPI37054.1 - 4.7e-25 87.4 0.0 8.5e-25 86.5 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3176 PF11374.3 KPI37055.1 - 4.1e-28 97.4 0.1 4.1e-28 97.4 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) SNF2_N PF00176.18 KPI37056.1 - 1.4e-36 125.7 0.0 2e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KPI37056.1 - 2e-13 50.0 0.0 4.1e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KPI37056.1 - 2.2e-07 29.9 0.0 8.5e-07 28.0 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 MFS_1 PF07690.11 KPI37057.1 - 5.9e-28 97.5 48.5 1.9e-20 72.9 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI37057.1 - 0.00043 18.9 31.8 0.0021 16.6 4.5 3.4 2 2 1 3 3 3 3 Sugar (and other) transporter NUDIX PF00293.23 KPI37058.1 - 1.5e-07 31.1 0.1 2.8e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain ADH_zinc_N PF00107.21 KPI37059.1 - 1e-11 44.5 0.1 1.9e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI37059.1 - 4.7e-05 23.1 0.0 0.00063 19.4 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KPI37059.1 - 0.029 15.2 0.0 0.066 14.0 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Inositol_P PF00459.20 KPI37060.1 - 7.4e-61 205.8 0.1 9.1e-61 205.5 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family adh_short PF00106.20 KPI37061.1 - 3.8e-26 91.9 0.2 5.8e-26 91.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI37061.1 - 3.2e-18 66.3 0.1 3.6e-18 66.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI37061.1 - 4.4e-09 36.2 0.3 7.4e-09 35.5 0.2 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KPI37061.1 - 8.7e-06 25.1 0.3 2.8e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 KPI37061.1 - 0.00012 22.2 0.2 0.00024 21.1 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 KPI37061.1 - 0.00024 20.3 0.1 0.0035 16.5 0.0 2.2 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) TrkA_N PF02254.13 KPI37061.1 - 0.047 13.6 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF4267 PF14087.1 KPI37063.1 - 5.6e-09 35.5 2.2 9e-09 34.9 1.6 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4267) PBCV_basic_adap PF08789.5 KPI37064.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 PBCV-specific basic adaptor domain A_deaminase PF00962.17 KPI37065.1 - 8.1e-53 179.4 0.0 1e-52 179.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase UIM PF02809.15 KPI37066.1 - 0.15 11.7 5.4 1.7 8.4 0.5 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif DIOX_N PF14226.1 KPI37067.1 - 4.3e-17 62.6 0.2 9.2e-17 61.6 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI37067.1 - 7e-13 48.7 0.0 1.8e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PIR PF00399.14 KPI37069.1 - 1.3e-71 233.6 124.5 9.9e-07 27.8 1.1 13.4 6 5 7 13 13 13 13 Yeast PIR protein repeat Lactamase_B PF00753.22 KPI37070.1 - 1.2e-10 41.4 0.3 1.8e-10 40.8 0.2 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI37070.1 - 0.00029 20.4 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ADH_zinc_N PF00107.21 KPI37072.1 - 1.2e-12 47.5 0.3 8e-12 44.8 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI37072.1 - 0.001 18.8 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ABC1 PF03109.11 KPI37073.1 - 1.9e-31 108.4 0.0 2.9e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Vac14_Fig4_bd PF11916.3 KPI37074.1 - 6.7e-82 273.0 5.1 6.7e-82 273.0 3.5 1.6 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KPI37074.1 - 1.9e-45 153.1 0.1 3.5e-42 142.7 0.0 4.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KPI37074.1 - 3.1e-08 33.0 2.8 0.00027 20.7 0.0 6.2 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 KPI37074.1 - 1.1e-07 32.1 3.5 0.00025 21.4 0.0 5.0 4 0 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.1 KPI37074.1 - 2.8e-07 30.7 6.1 0.0019 18.4 0.0 5.4 6 1 1 7 7 7 2 HEAT repeats Arm PF00514.18 KPI37074.1 - 0.0012 18.5 0.0 0.33 10.8 0.0 3.8 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat DUF4551 PF15087.1 KPI37074.1 - 0.024 13.0 0.1 5.8 5.1 0.1 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF4551) p450 PF00067.17 KPI37075.1 - 2.6e-35 121.8 0.0 3.3e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 KPI37076.1 - 5e-09 35.6 0.0 9.4e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain PHD PF00628.24 KPI37076.1 - 7.2e-07 28.7 11.6 1.4e-06 27.8 8.1 1.5 1 0 0 1 1 1 1 PHD-finger Kdo PF06293.9 KPI37076.1 - 3.6e-06 26.1 0.0 8.2e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KPI37076.1 - 3.3e-05 23.7 0.1 0.0043 16.8 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 KPI37076.1 - 0.025 13.7 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) AP3B1_C PF14796.1 KPI37076.1 - 0.031 13.9 0.1 0.097 12.3 0.0 1.8 2 0 0 2 2 2 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Choline_kinase PF01633.15 KPI37076.1 - 0.036 13.6 0.5 8.3 5.9 0.1 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase PHD_2 PF13831.1 KPI37076.1 - 0.43 9.9 6.0 0.85 8.9 4.2 1.5 1 0 0 1 1 1 0 PHD-finger CBFB_NFYA PF02045.10 KPI37076.1 - 7.1 7.2 6.5 23 5.5 2.3 2.6 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Cactin_mid PF10312.4 KPI37077.1 - 2.6e-59 199.7 0.5 5e-59 198.7 0.4 1.5 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 KPI37077.1 - 9.7e-44 147.9 0.0 1.3e-42 144.3 0.0 2.1 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein RasGAP_C PF03836.10 KPI37079.1 - 4.1e-46 156.2 5.0 2.2e-45 153.8 3.5 2.4 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 KPI37079.1 - 1.7e-36 125.7 0.0 7.4e-36 123.6 0.0 2.2 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 KPI37079.1 - 1.5e-12 45.9 45.8 0.32 10.7 0.0 15.6 16 0 0 16 16 16 7 IQ calmodulin-binding motif CH PF00307.26 KPI37079.1 - 2.4e-12 46.8 0.0 7.7e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KPI37079.1 - 0.025 14.2 0.0 0.076 12.6 0.0 1.8 1 0 0 1 1 1 0 CAMSAP CH domain Cyclase_polyket PF04673.7 KPI37079.1 - 0.044 13.8 0.0 0.17 11.9 0.0 2.0 1 0 0 1 1 1 0 Polyketide synthesis cyclase FAA_hydrolase PF01557.13 KPI37080.1 - 2.7e-60 203.5 0.0 3.7e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.4 KPI37080.1 - 0.068 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2437) Zn_clus PF00172.13 KPI37081.1 - 3.7e-07 29.9 10.1 5.9e-07 29.2 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KPI37081.1 - 2.2 7.0 4.9 1 8.1 1.6 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain MFS_1 PF07690.11 KPI37082.1 - 1.4e-31 109.4 25.5 1.4e-31 109.4 17.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3382 PF11862.3 KPI37082.1 - 0.38 10.6 0.0 0.38 10.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) DUF3784 PF12650.2 KPI37082.1 - 0.38 10.7 0.0 0.38 10.7 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) zf-RING_2 PF13639.1 KPI37083.1 - 1.7e-08 34.1 1.0 1.7e-08 34.1 0.7 3.4 3 1 0 3 3 2 1 Ring finger domain PHD PF00628.24 KPI37083.1 - 5.4e-07 29.1 10.7 5.4e-07 29.1 7.4 2.6 2 1 0 2 2 2 1 PHD-finger zf-C3HC4_2 PF13923.1 KPI37083.1 - 1.4e-06 28.1 1.2 1.4e-06 28.1 0.8 3.2 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KPI37083.1 - 7.3e-06 25.5 1.0 7.3e-06 25.5 0.7 3.3 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI37083.1 - 8.6e-06 25.3 0.3 8.6e-06 25.3 0.2 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI37083.1 - 2.4e-05 23.9 0.4 2.4e-05 23.9 0.3 3.0 4 1 0 4 4 3 1 zinc-RING finger domain zf-rbx1 PF12678.2 KPI37083.1 - 4e-05 23.6 1.8 5.5e-05 23.1 0.1 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger PHD_2 PF13831.1 KPI37083.1 - 0.0005 19.3 4.0 0.0005 19.3 2.8 2.7 3 0 0 3 3 3 1 PHD-finger DZR PF12773.2 KPI37083.1 - 0.0012 18.6 1.8 0.0012 18.6 1.2 2.5 2 0 0 2 2 2 1 Double zinc ribbon zf-Apc11 PF12861.2 KPI37083.1 - 0.029 14.2 0.1 0.029 14.2 0.1 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KPI37083.1 - 0.044 13.5 0.6 0.57 9.9 0.0 2.5 2 0 0 2 2 2 0 RING-type zinc-finger Ima1_N PF09779.4 KPI37083.1 - 0.74 10.3 7.7 0.27 11.7 0.3 3.1 3 0 0 3 3 3 0 Ima1 N-terminal domain Cytochrom_B561 PF03188.11 KPI37085.1 - 1.7e-08 34.3 11.8 3.1e-08 33.5 5.8 2.8 2 1 1 3 3 3 1 Eukaryotic cytochrome b561 DOMON PF03351.12 KPI37085.1 - 0.0054 16.6 0.1 0.01 15.7 0.1 1.5 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 KPI37085.1 - 0.0094 15.5 7.1 0.0094 15.5 4.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Shisa PF13908.1 KPI37085.1 - 0.018 15.2 0.1 0.054 13.6 0.0 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 KPI37085.1 - 0.14 12.6 0.0 0.14 12.6 0.0 2.6 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 KPI37085.1 - 0.23 11.0 0.6 0.42 10.2 0.4 1.4 1 0 0 1 1 1 0 Rifin/stevor family Ferric_reduct PF01794.14 KPI37085.1 - 7.3 6.7 12.8 98 3.0 8.8 2.4 1 1 0 1 1 1 0 Ferric reductase like transmembrane component DUF2306 PF10067.4 KPI37085.1 - 9.4 6.4 12.4 1.1 9.4 1.6 2.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) Ribosomal_L37ae PF01780.14 KPI37086.1 - 2.7e-40 136.1 10.5 2.9e-40 136.0 7.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 KPI37086.1 - 0.0018 18.0 2.1 0.0026 17.5 1.4 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 KPI37086.1 - 0.01 15.2 4.5 0.49 9.9 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Thymidylat_synt PF00303.14 KPI37086.1 - 0.086 11.8 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Thymidylate synthase NOB1_Zn_bind PF08772.6 KPI37086.1 - 0.089 12.6 3.6 0.58 10.0 2.4 2.1 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-BED PF02892.10 KPI37086.1 - 0.21 11.3 5.7 1.9 8.2 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger Glyco_hydro_88 PF07470.8 KPI37088.1 - 7.7e-11 41.6 0.0 4.3e-09 35.8 0.0 2.7 2 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 GMC_oxred_N PF00732.14 KPI37089.1 - 2.5e-44 151.6 0.2 4e-44 150.9 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI37089.1 - 1.1e-24 87.3 0.7 1.1e-24 87.3 0.5 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KPI37089.1 - 3.7e-06 26.0 0.1 0.028 13.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 KPI37089.1 - 4.5e-06 26.6 0.8 0.0083 16.0 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI37089.1 - 7.5e-05 21.7 0.3 0.022 13.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Carboxyl_trans PF01039.17 KPI37089.1 - 0.0056 15.0 0.0 0.013 13.9 0.0 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain Thi4 PF01946.12 KPI37089.1 - 0.066 12.3 0.0 0.39 9.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 KPI37089.1 - 0.083 11.7 0.2 1.2 7.9 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein HET PF06985.6 KPI37090.1 - 2.2e-33 115.3 0.3 4.4e-33 114.3 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Vwaint PF14624.1 KPI37090.1 - 0.0075 16.3 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like DUF500 PF04366.7 KPI37093.1 - 1.4e-28 98.8 2.2 2e-28 98.3 1.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF500) PBCV_basic_adap PF08789.5 KPI37093.1 - 0.016 14.8 0.0 0.016 14.8 0.0 2.5 3 0 0 3 3 3 0 PBCV-specific basic adaptor domain Sel1 PF08238.7 KPI37094.1 - 5.3e-34 115.8 34.1 0.00014 22.3 0.0 12.8 12 0 0 12 12 12 7 Sel1 repeat TPR_11 PF13414.1 KPI37094.1 - 0.0021 17.6 16.4 0.061 12.9 0.3 6.1 5 2 2 7 7 7 3 TPR repeat TPR_7 PF13176.1 KPI37094.1 - 0.09 12.6 7.9 17 5.5 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 KPI37094.1 - 0.4 11.4 26.6 3.6 8.3 0.9 7.2 7 1 0 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.12 KPI37094.1 - 0.88 9.6 15.8 8.3 6.6 0.1 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat EHN PF06441.7 KPI37095.1 - 4.6e-19 68.3 0.3 8.5e-19 67.5 0.2 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KPI37095.1 - 1.6e-12 47.7 0.2 1.8e-12 47.6 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI37095.1 - 1.6e-06 27.8 0.1 7.2e-06 25.7 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Glyco_hydro_61 PF03443.9 KPI37097.1 - 1.4e-71 240.8 0.9 1.7e-71 240.5 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF605 PF04652.11 KPI37099.1 - 0.83 8.9 11.6 1.2 8.4 8.0 1.2 1 0 0 1 1 1 0 Vta1 like Acetyltransf_1 PF00583.19 KPI37100.1 - 4.9e-17 61.7 0.0 2.1e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KPI37100.1 - 2e-07 31.2 0.4 1.4e-06 28.5 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KPI37100.1 - 6.2e-07 29.5 0.0 1.9e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI37100.1 - 1.2e-05 25.4 0.0 2.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KPI37100.1 - 0.00045 20.0 0.0 0.00091 19.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KPI37100.1 - 0.0013 18.4 0.0 0.0047 16.6 0.0 1.9 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KPI37100.1 - 0.0015 18.3 0.1 0.0049 16.7 0.0 2.0 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase dCMP_cyt_deam_1 PF00383.17 KPI37102.1 - 5.2e-10 38.8 0.0 6.9e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Osmo_CC PF08946.5 KPI37102.1 - 0.11 12.5 0.1 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Senescence PF06911.7 KPI37103.1 - 2.9e-49 167.1 8.8 4.1e-49 166.6 6.1 1.2 1 0 0 1 1 1 1 Senescence-associated protein Saccharop_dh PF03435.13 KPI37104.1 - 2.2e-20 72.9 0.0 3e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KPI37104.1 - 0.0058 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DUF1349 PF07081.6 KPI37105.1 - 3e-07 29.9 0.0 1.8e-06 27.4 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) Gag_p6 PF08705.6 KPI37106.1 - 0.0062 16.5 0.7 0.0062 16.5 0.5 2.1 2 1 0 2 2 2 1 Gag protein p6 HemS PF05171.7 KPI37106.1 - 0.041 13.6 0.0 0.045 13.5 0.0 1.0 1 0 0 1 1 1 0 Haemin-degrading HemS.ChuX domain CPSF100_C PF13299.1 KPI37108.1 - 4.5 7.4 7.4 4.3 7.4 1.9 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Ssu72 PF04722.8 KPI37110.1 - 2.4e-79 265.1 0.0 2.9e-79 264.9 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Ilar_coat PF01787.11 KPI37110.1 - 2.7 7.5 6.2 3.6 7.1 3.9 1.5 1 1 0 1 1 1 0 Ilarvirus coat protein DEC-1_N PF04625.8 KPI37110.1 - 7.2 5.1 15.4 12 4.4 10.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Cu-oxidase_3 PF07732.10 KPI37111.1 - 2.6e-42 143.2 5.1 8.3e-41 138.4 0.3 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KPI37111.1 - 2.5e-29 101.5 12.8 6.7e-25 87.1 3.7 4.3 3 2 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 KPI37111.1 - 1e-28 100.2 0.9 2.5e-28 98.9 0.0 2.2 3 0 0 3 3 3 1 Multicopper oxidase Prefoldin PF02996.12 KPI37113.1 - 3.7e-25 87.9 4.3 7.4e-23 80.4 1.5 3.0 1 1 1 2 2 2 1 Prefoldin subunit Filament PF00038.16 KPI37113.1 - 0.0067 15.9 5.2 0.068 12.6 1.2 2.1 2 0 0 2 2 2 2 Intermediate filament protein Prefoldin_2 PF01920.15 KPI37113.1 - 0.011 15.4 8.7 0.032 13.9 0.2 3.4 1 1 3 4 4 4 0 Prefoldin subunit Sec2p PF06428.6 KPI37113.1 - 0.017 14.9 5.2 0.4 10.5 0.1 2.7 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Telomere_reg-2 PF10193.4 KPI37113.1 - 0.018 15.3 1.2 0.065 13.4 0.2 2.0 2 0 0 2 2 2 0 Telomere length regulation protein Laminin_II PF06009.7 KPI37113.1 - 0.068 12.9 1.6 0.12 12.0 0.1 2.0 2 0 0 2 2 2 0 Laminin Domain II TMPIT PF07851.8 KPI37113.1 - 0.12 11.3 0.8 0.19 10.7 0.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein Spc7 PF08317.6 KPI37113.1 - 0.15 10.6 5.0 2 6.9 0.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 KPI37113.1 - 1.8 8.3 6.9 2.3 7.9 1.6 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Methyltransf_28 PF02636.12 KPI37114.1 - 1.3e-68 231.1 0.0 1.8e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase adh_short PF00106.20 KPI37114.1 - 1e-25 90.6 2.0 1.8e-25 89.7 1.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI37114.1 - 3.1e-11 43.5 0.0 5.5e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI37114.1 - 2.6e-10 40.2 0.6 5.3e-10 39.2 0.4 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI37114.1 - 9.5e-05 21.9 0.1 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI37114.1 - 0.00052 20.0 0.2 0.0012 18.8 0.1 1.6 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KPI37114.1 - 0.0024 17.1 0.1 0.0041 16.4 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Eno-Rase_NADH_b PF12242.3 KPI37114.1 - 0.074 12.8 0.1 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1237 PF06824.6 KPI37115.1 - 8.7e-161 535.2 0.0 1e-160 535.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Ceramidase_alk PF04734.8 KPI37116.1 - 6.4e-271 900.0 0.0 7.3e-271 899.8 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Pkinase PF00069.20 KPI37117.1 - 4.4e-58 196.4 0.0 7.7e-58 195.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI37117.1 - 8.6e-30 103.6 0.0 5.1e-24 84.7 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KPI37117.1 - 1.8e-05 23.8 0.1 0.014 14.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KPI37117.1 - 0.00071 19.3 0.0 0.0021 17.8 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KPI37117.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KPI37117.1 - 0.028 13.4 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_6 PF12697.2 KPI37118.1 - 7.7e-19 68.4 0.2 1.7e-18 67.3 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI37118.1 - 9.1e-12 44.9 0.1 1.6e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI37118.1 - 6.4e-05 22.6 2.5 0.0084 15.6 0.4 3.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KPI37118.1 - 0.0017 18.1 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Glyco_hydro_65C PF03633.10 KPI37118.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain adh_short PF00106.20 KPI37119.1 - 2.8e-23 82.6 0.1 5.4e-23 81.7 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI37119.1 - 1e-18 67.9 0.0 1.3e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI37119.1 - 0.00055 19.6 0.2 0.0011 18.6 0.1 1.5 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 KPI37119.1 - 0.0026 17.0 0.1 0.0045 16.2 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI37119.1 - 0.0091 16.0 0.6 0.043 13.8 0.1 2.1 2 1 0 2 2 2 1 NADH(P)-binding ADH_zinc_N PF00107.21 KPI37119.1 - 0.026 14.0 0.4 0.058 12.9 0.1 1.8 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Glyco_hydro_11 PF00457.12 KPI37120.1 - 1.3e-62 210.3 18.7 1.5e-62 210.1 12.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 FYVE PF01363.16 KPI37122.1 - 8.1e-16 57.6 9.0 1.2e-15 57.1 6.2 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 KPI37122.1 - 0.019 14.8 7.6 0.019 14.8 5.2 1.9 2 0 0 2 2 2 0 AN1-like Zinc finger IBR PF01485.16 KPI37122.1 - 0.036 13.9 1.3 0.036 13.9 0.9 1.6 2 0 0 2 2 2 0 IBR domain DUF2695 PF10905.3 KPI37122.1 - 0.06 13.0 0.7 0.96 9.2 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2695) zf-RING_5 PF14634.1 KPI37122.1 - 3.1 7.5 11.5 20 5.0 8.2 2.0 1 1 1 2 2 2 0 zinc-RING finger domain MFS_1 PF07690.11 KPI37123.1 - 1.4e-27 96.3 31.7 1.7e-27 96.0 21.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 KPI37123.1 - 0.00025 21.0 4.5 0.0029 17.6 0.1 3.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1228) DUF2919 PF11143.3 KPI37123.1 - 0.68 9.7 4.9 0.41 10.4 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) DUF3827 PF12877.2 KPI37124.1 - 4.5 5.2 5.3 7.2 4.5 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF1242 PF06842.7 KPI37125.1 - 0.081 12.4 0.3 14 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1242) GNAT_acetyltran PF12746.2 KPI37126.1 - 0.11 11.3 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase DUF3425 PF11905.3 KPI37129.1 - 1.9e-12 47.2 0.2 4.5e-12 46.0 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) ABC_membrane PF00664.18 KPI37130.1 - 9.4e-31 107.2 8.4 1.9e-30 106.2 5.8 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KPI37130.1 - 2.8e-30 105.3 0.0 7.6e-30 103.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 KPI37130.1 - 1.2e-05 24.6 0.5 0.00028 20.1 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KPI37130.1 - 0.0003 20.8 0.0 0.045 13.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KPI37130.1 - 0.0065 15.6 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KPI37130.1 - 0.01 15.3 0.1 0.029 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KPI37130.1 - 0.026 14.5 0.1 0.083 12.8 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.1 KPI37130.1 - 0.32 10.9 2.1 0.77 9.7 0.2 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit TFR_dimer PF04253.10 KPI37131.1 - 5.3e-21 74.4 0.0 9.9e-21 73.6 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KPI37131.1 - 3e-12 46.6 0.0 5.1e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KPI37131.1 - 1e-06 28.3 0.1 1.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 PA domain Cu2_monoox_C PF03712.10 KPI37131.1 - 0.12 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain FMO-like PF00743.14 KPI37132.1 - 1.7e-70 237.7 0.0 1.9e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KPI37132.1 - 1.8e-29 103.2 0.0 6.5e-28 98.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI37132.1 - 5.5e-14 52.5 0.0 7.5e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI37132.1 - 1.5e-09 37.8 0.3 2.5e-07 30.6 0.0 3.8 4 1 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KPI37132.1 - 2e-08 34.1 0.0 5.3e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI37132.1 - 3.7e-08 32.6 0.0 5.9e-07 28.7 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KPI37132.1 - 1.7e-07 31.5 0.2 0.011 16.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI37132.1 - 2.6e-05 23.2 0.1 0.0025 16.7 0.0 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KPI37132.1 - 7.2e-05 22.9 0.0 0.28 11.4 0.0 2.7 2 1 0 2 2 2 2 Putative NAD(P)-binding Thi4 PF01946.12 KPI37132.1 - 0.00016 20.8 0.2 0.00053 19.1 0.0 1.8 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.14 KPI37132.1 - 0.0011 18.1 0.1 0.002 17.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_10 PF13460.1 KPI37132.1 - 0.0012 18.8 0.1 1.6 8.6 0.0 3.1 3 0 0 3 3 3 1 NADH(P)-binding Shikimate_DH PF01488.15 KPI37132.1 - 0.0023 18.0 1.2 1.4 9.0 0.1 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 KPI37132.1 - 0.0053 16.1 0.0 0.59 9.4 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 KPI37132.1 - 0.0097 15.0 0.1 2.7 7.0 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 KPI37132.1 - 0.014 13.9 0.1 0.021 13.2 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 KPI37132.1 - 0.033 13.9 0.0 7.1 6.3 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rad54_N PF08658.5 KPI37133.1 - 4.3e-46 157.1 0.1 6.1e-46 156.6 0.1 1.2 1 0 0 1 1 1 1 Rad54 N terminal ADIP PF11559.3 KPI37134.1 - 1.1e-33 116.2 15.5 2.4e-33 115.1 10.7 1.6 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF1635 PF07795.6 KPI37134.1 - 0.32 10.3 9.8 0.16 11.3 1.7 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1635) V_ATPase_I PF01496.14 KPI37134.1 - 0.85 7.4 2.7 1.6 6.5 1.9 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L6e PF01159.14 KPI37134.1 - 2.9 8.1 7.8 3.7 7.8 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein L6e RasGAP_C PF03836.10 KPI37135.1 - 0.077 12.6 11.5 3.3 7.3 2.6 3.2 3 0 0 3 3 3 0 RasGAP C-terminus Adeno_PIX PF03955.9 KPI37135.1 - 0.44 11.0 3.8 0.21 12.1 0.7 1.9 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) APG6 PF04111.7 KPI37135.1 - 8.4 5.3 7.5 15 4.5 5.2 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 SH3_1 PF00018.23 KPI37136.1 - 7.5e-11 41.2 0.0 1.2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KPI37136.1 - 9.9e-11 41.0 0.0 1.8e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KPI37136.1 - 3.4e-07 29.6 0.0 5.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain 2-Hacid_dh_C PF02826.14 KPI37137.1 - 8e-50 168.4 0.0 1.3e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KPI37137.1 - 2.2e-16 59.5 0.0 3.3e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Fungal_trans PF04082.13 KPI37137.1 - 3.1e-11 42.6 0.9 9e-11 41.1 0.0 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain NAD_binding_2 PF03446.10 KPI37137.1 - 0.0054 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase HCO3_cotransp PF00955.16 KPI37137.1 - 0.017 13.8 0.0 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 HCO3- transporter family PspA_IM30 PF04012.7 KPI37137.1 - 0.11 11.8 2.3 0.094 12.0 0.4 1.7 2 0 0 2 2 2 0 PspA/IM30 family UQ_con PF00179.21 KPI37138.1 - 9.3e-47 157.9 0.0 1.1e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KPI37138.1 - 0.00064 19.5 0.4 0.001 18.9 0.2 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KPI37138.1 - 0.003 17.2 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.1 KPI37138.1 - 0.0032 17.2 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B CAF1 PF04857.15 KPI37139.1 - 2.5e-44 151.5 0.0 3.2e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 KPI37139.1 - 0.0008 18.9 0.0 0.49 9.8 0.0 2.4 2 0 0 2 2 2 2 3'-5' exonuclease FAM212 PF15342.1 KPI37139.1 - 0.12 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 FAM212 family Pkinase PF00069.20 KPI37140.1 - 3.7e-61 206.5 0.0 5e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI37140.1 - 1.1e-25 90.1 0.0 1.5e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI37140.1 - 3.6e-08 32.7 0.0 4.7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KPI37140.1 - 0.00043 19.4 0.0 0.00097 18.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KPI37140.1 - 0.0093 15.7 0.0 0.034 13.8 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family adh_short PF00106.20 KPI37141.1 - 2e-30 105.9 2.3 2.7e-30 105.4 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI37141.1 - 7.1e-19 68.5 0.1 8.3e-19 68.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI37141.1 - 5.9e-13 48.8 1.0 9.2e-13 48.2 0.7 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI37141.1 - 0.00065 19.1 0.2 0.0019 17.6 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI37141.1 - 0.0024 17.9 0.3 0.0059 16.6 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KPI37141.1 - 0.02 13.7 0.4 0.079 11.8 0.1 2.0 1 1 1 2 2 2 0 RmlD substrate binding domain NmrA PF05368.8 KPI37141.1 - 0.027 13.7 0.3 0.047 12.9 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.14 KPI37141.1 - 0.055 12.1 0.3 0.083 11.5 0.1 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sugar_tr PF00083.19 KPI37142.1 - 6.3e-07 28.3 0.0 7.3e-07 28.1 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI37142.1 - 8.8e-05 21.3 0.0 9.8e-05 21.2 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 KPI37142.1 - 0.0038 15.7 0.3 0.0046 15.4 0.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like INSIG PF07281.7 KPI37142.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) Pyr_redox_3 PF13738.1 KPI37143.1 - 8.4e-26 91.2 0.0 1.6e-25 90.3 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI37143.1 - 5.7e-12 44.6 0.2 8.8e-11 40.6 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI37143.1 - 1.5e-11 44.1 0.1 1.6e-09 37.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI37143.1 - 1.1e-10 40.9 0.0 1e-07 31.2 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KPI37143.1 - 8.6e-07 29.0 0.2 0.0061 16.4 0.0 3.3 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI37143.1 - 6e-06 25.5 0.0 0.0011 18.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KPI37143.1 - 8e-06 24.9 0.1 0.00036 19.5 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KPI37143.1 - 2.6e-05 23.3 0.0 0.0095 14.8 0.0 2.8 2 1 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.22 KPI37143.1 - 8.4e-05 22.9 0.1 0.031 14.6 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KPI37143.1 - 0.003 17.6 0.0 0.58 10.2 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 KPI37143.1 - 0.0043 16.8 1.2 0.25 11.0 0.1 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding ApbA PF02558.11 KPI37143.1 - 0.0056 16.1 0.2 2 7.8 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 KPI37143.1 - 0.017 15.3 0.1 0.046 13.9 0.0 1.8 2 0 0 2 2 1 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 KPI37143.1 - 0.031 13.1 0.2 0.14 10.9 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Malic_M PF03949.10 KPI37143.1 - 0.11 12.0 0.1 15 5.0 0.0 2.4 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain p450 PF00067.17 KPI37144.1 - 7e-52 176.4 0.0 6.5e-51 173.2 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 GDPD PF03009.12 KPI37145.1 - 2e-05 24.2 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PIR PF00399.14 KPI37145.1 - 9.5e-05 21.6 1.9 9.5e-05 21.6 1.3 2.5 2 0 0 2 2 2 1 Yeast PIR protein repeat Kelch_4 PF13418.1 KPI37146.1 - 2e-32 110.7 12.3 1.3e-07 31.2 0.4 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KPI37146.1 - 2.3e-32 110.4 5.1 2e-05 24.3 0.1 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KPI37146.1 - 2.1e-31 107.3 21.4 3.1e-08 33.5 0.1 6.5 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.20 KPI37146.1 - 4.2e-31 106.2 1.5 1.3e-08 34.2 0.3 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KPI37146.1 - 6e-26 89.4 4.0 6.7e-07 29.2 0.4 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.10 KPI37146.1 - 5.8e-20 70.2 8.4 3.8e-07 29.6 0.2 6.7 6 0 0 6 6 6 4 Kelch motif RAG2 PF03089.9 KPI37146.1 - 0.027 13.2 0.4 1.1 7.8 0.0 3.3 4 0 0 4 4 4 0 Recombination activating protein 2 WEMBL PF05701.6 KPI37146.1 - 0.67 8.3 84.1 0.096 11.1 19.2 4.3 2 1 2 4 4 4 0 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 KPI37146.1 - 3.2 6.8 21.2 1.5 7.9 3.8 3.4 2 2 1 3 3 3 0 Reovirus sigma C capsid protein MFS_1 PF07690.11 KPI37148.1 - 1.8e-34 119.0 30.1 1.8e-34 119.0 20.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 KPI37148.1 - 1.5 8.9 0.0 1.5 8.9 0.0 3.5 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding WD40 PF00400.27 KPI37149.1 - 2.2e-19 68.5 12.0 4e-08 32.8 0.7 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat zf-ribbon_3 PF13248.1 KPI37149.1 - 0.0055 15.8 4.7 0.034 13.3 1.4 2.5 2 0 0 2 2 2 1 zinc-ribbon domain zf-rbx1 PF12678.2 KPI37149.1 - 0.0095 16.0 7.8 0.022 14.8 5.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger eIF2A PF08662.6 KPI37149.1 - 0.11 12.2 0.0 1.6 8.4 0.0 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A RNA_pol_Rbc25 PF08292.7 KPI37149.1 - 0.13 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 DZR PF12773.2 KPI37149.1 - 0.15 11.9 13.9 2.1 8.2 9.5 2.4 1 1 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.17 KPI37149.1 - 0.78 9.5 9.8 10 5.9 6.8 2.3 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Transp_cyt_pur PF02133.10 KPI37150.1 - 5.4e-20 71.3 27.1 1.2e-19 70.2 18.8 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4181 PF13789.1 KPI37150.1 - 5.8 6.8 10.6 9.2 6.2 0.8 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) tRNA-synt_2 PF00152.15 KPI37151.1 - 4.3e-50 170.3 0.0 8.8e-49 166.0 0.0 2.4 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) HDA2-3 PF11496.3 KPI37151.1 - 2.5e-10 39.6 0.0 1.9e-09 36.7 0.0 2.3 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 tRNA_anti-codon PF01336.20 KPI37151.1 - 2.2e-07 30.6 0.0 4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Microtub_assoc PF07989.6 KPI37151.1 - 0.82 9.5 8.5 7 6.5 0.8 3.5 3 1 1 4 4 4 0 Microtubule associated HALZ PF02183.13 KPI37151.1 - 6.7 6.5 16.4 0.66 9.7 0.2 4.5 3 1 1 4 4 4 0 Homeobox associated leucine zipper FAD_binding_3 PF01494.14 KPI37152.1 - 1.5e-17 63.6 0.0 4.4e-13 49.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KPI37152.1 - 4.5e-12 45.5 1.2 8e-08 31.5 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI37152.1 - 1.2e-05 25.1 0.7 3.6e-05 23.6 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI37152.1 - 1.6e-05 23.9 0.3 4.1e-05 22.6 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KPI37152.1 - 0.00027 20.8 0.0 0.00088 19.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI37152.1 - 0.00038 20.7 0.0 0.073 13.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI37152.1 - 0.00071 18.1 0.3 0.0034 15.9 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 KPI37152.1 - 0.023 13.6 0.3 0.062 12.2 0.2 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.2 KPI37152.1 - 0.035 13.1 1.1 0.055 12.5 0.8 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 KPI37152.1 - 0.067 12.0 0.0 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.19 KPI37152.1 - 0.079 12.0 0.2 1.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FMO-like PF00743.14 KPI37152.1 - 0.13 10.4 0.1 0.23 9.6 0.1 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like HET PF06985.6 KPI37153.1 - 2.5e-24 86.0 0.1 3e-24 85.7 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3517 PF12030.3 KPI37155.1 - 0.14 10.7 0.1 0.24 9.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) MFS_1 PF07690.11 KPI37157.1 - 7.6e-38 130.1 25.8 7.6e-38 130.1 17.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI37157.1 - 7.3e-16 57.7 22.5 2.1e-15 56.2 5.8 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KPI37157.1 - 5.1e-10 38.1 5.2 5.1e-10 38.1 3.6 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 KPI37157.1 - 0.0002 19.9 7.5 0.00043 18.9 5.2 1.4 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like SsgA PF04686.7 KPI37157.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA OATP PF03137.15 KPI37157.1 - 0.2 9.6 7.4 0.022 12.8 1.6 2.1 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Aldo_ket_red PF00248.16 KPI37158.1 - 1.4e-43 148.7 0.0 1.7e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SRP72 PF08492.7 KPI37159.1 - 3.3e-17 62.5 2.3 1.1e-16 60.9 1.6 1.9 1 0 0 1 1 1 1 SRP72 RNA-binding domain SPO22 PF08631.5 KPI37159.1 - 0.0045 16.1 0.2 0.0045 16.1 0.1 2.6 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 KPI37159.1 - 0.046 13.6 15.2 0.38 10.7 0.1 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KPI37159.1 - 0.075 13.6 21.5 3.8 8.4 0.2 7.4 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_19 PF14559.1 KPI37159.1 - 0.36 11.2 29.8 4.1 7.8 0.0 6.3 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 KPI37159.1 - 0.37 10.8 18.5 2 8.5 1.4 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KPI37159.1 - 0.53 10.8 15.6 1.8 9.2 1.3 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Apc3 PF12895.2 KPI37159.1 - 0.67 10.1 13.3 0.42 10.7 0.2 4.3 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KPI37159.1 - 9 6.0 13.4 0.87 9.2 0.2 4.3 4 1 0 4 4 4 0 TPR repeat Lumazine_bd PF12870.2 KPI37160.1 - 0.02 14.9 1.9 0.031 14.3 1.3 1.3 1 0 0 1 1 1 0 Lumazine-binding domain PMSI1 PF15322.1 KPI37160.1 - 0.1 11.6 1.1 0.11 11.6 0.8 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Sugar_tr PF00083.19 KPI37161.1 - 4e-18 65.2 8.2 4e-18 65.2 5.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI37161.1 - 1.2e-10 40.6 25.6 1.7e-10 40.1 17.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KPI37162.1 - 2.6e-06 26.2 0.7 5.2e-06 25.3 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_31 PF01055.21 KPI37163.1 - 7.1e-120 400.8 0.3 9.2e-120 400.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KPI37163.1 - 1.3e-17 63.3 0.2 3.1e-17 62.1 0.2 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like Abhydrolase_4 PF08386.5 KPI37164.1 - 7.6e-23 80.3 0.0 1.5e-21 76.2 0.0 2.3 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 KPI37164.1 - 1.2e-08 34.8 0.0 3e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI37164.1 - 0.01 15.6 0.0 0.027 14.3 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Fungal_trans PF04082.13 KPI37165.1 - 1.2e-22 80.0 0.0 2.1e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Beta-lactamase PF00144.19 KPI37165.1 - 4.5e-21 75.2 0.1 8.9e-21 74.2 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase PrsW-protease PF13367.1 KPI37165.1 - 0.038 13.1 0.1 0.08 12.1 0.1 1.4 1 0 0 1 1 1 0 Protease prsW family DUF1805 PF08827.6 KPI37166.1 - 0.086 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) PhoD PF09423.5 KPI37167.1 - 8.4e-153 509.1 1.4 9.7e-153 508.9 1.0 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase Pilin_PilA PF14245.1 KPI37167.1 - 0.1 13.0 2.2 0.37 11.3 0.8 2.4 2 1 0 2 2 2 0 Type IV pilin PilA DUF3455 PF11937.3 KPI37168.1 - 7.2e-32 110.7 0.1 1.3e-31 109.9 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3455) CK_II_beta PF01214.13 KPI37170.1 - 8.6e-72 240.5 0.2 1.3e-71 239.9 0.2 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Oxysterol_BP PF01237.13 KPI37171.1 - 8.4e-118 392.8 0.2 1.6e-117 391.9 0.1 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 KPI37171.1 - 3.3e-40 136.0 0.9 3.4e-39 132.8 0.1 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KPI37171.1 - 1.1e-05 25.5 0.2 0.00018 21.6 0.0 2.8 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KPI37171.1 - 0.017 15.3 6.0 0.056 13.7 1.4 3.3 2 1 0 2 2 2 0 Pleckstrin homology domain PH_3 PF14593.1 KPI37171.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 PH domain RNA_pol_Rpb5_C PF01191.14 KPI37172.1 - 2.6e-35 119.8 0.1 4.1e-35 119.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KPI37172.1 - 6.4e-21 74.5 0.0 1e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain SH3_2 PF07653.12 KPI37172.1 - 0.079 12.4 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Ribonuclease PF00545.15 KPI37173.1 - 3.9e-15 55.6 0.3 5.2e-15 55.2 0.2 1.2 1 0 0 1 1 1 1 ribonuclease UCH PF00443.24 KPI37175.1 - 2.6e-24 85.7 0.0 4.7e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KPI37175.1 - 1.8e-10 40.7 0.0 3.7e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AflR PF08493.5 KPI37175.1 - 0.16 10.9 10.7 0.32 9.9 7.4 1.4 1 0 0 1 1 1 0 Aflatoxin regulatory protein Mito_carr PF00153.22 KPI37177.1 - 2.6e-56 187.3 1.5 5.7e-19 67.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrpF PF04303.8 KPI37178.1 - 1.8e-49 168.5 0.0 1.3e-41 142.6 0.0 2.2 2 0 0 2 2 2 2 PrpF protein Ank_2 PF12796.2 KPI37179.1 - 4.8e-27 94.1 0.1 4.2e-17 62.2 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ribosomal_L7Ae PF01248.21 KPI37179.1 - 1.5e-26 91.7 1.2 3e-26 90.7 0.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ank PF00023.25 KPI37179.1 - 3.4e-19 67.6 2.9 3.2e-06 26.6 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 KPI37179.1 - 6.9e-19 67.8 0.0 1.9e-06 28.2 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KPI37179.1 - 1.9e-17 62.8 3.6 1.5e-06 28.2 0.0 5.6 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI37179.1 - 5.9e-14 50.7 0.2 0.00062 19.7 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat CorA PF01544.13 KPI37180.1 - 6.9e-12 44.9 0.0 1.2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein EMP70 PF02990.11 KPI37180.1 - 0.26 9.6 2.4 0.41 9.0 1.7 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 Nol1_Nop2_Fmu PF01189.12 KPI37181.1 - 2.8e-27 95.8 0.0 1e-16 61.2 0.0 4.5 4 1 0 4 4 4 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KPI37181.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF3085 PF11284.3 KPI37181.1 - 0.021 14.9 0.0 0.067 13.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) FtsJ PF01728.14 KPI37181.1 - 0.031 14.2 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF3292 PF11696.3 KPI37182.1 - 1.4e-193 644.3 0.0 5.5e-137 457.3 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) PRT_C PF08372.5 KPI37182.1 - 0.0022 17.4 0.9 0.009 15.5 0.4 1.9 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal Pex24p PF06398.6 KPI37182.1 - 0.022 13.5 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin MFS_1 PF07690.11 KPI37183.1 - 2.9e-31 108.4 31.9 4.2e-30 104.6 22.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF998 PF06197.8 KPI37183.1 - 0.36 10.0 20.9 0.023 13.9 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF998) CHCH PF06747.8 KPI37184.1 - 0.038 13.9 1.5 0.089 12.7 1.1 1.6 1 1 1 2 2 2 0 CHCH domain Pet191_N PF10203.4 KPI37184.1 - 0.078 13.0 2.6 0.53 10.3 0.6 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Fer4 PF00037.22 KPI37185.1 - 2.8e-14 52.0 16.1 1.8e-08 33.6 2.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KPI37185.1 - 4.3e-13 49.4 10.2 6.6e-13 48.8 7.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 KPI37185.1 - 5.5e-11 42.0 21.1 4.8e-09 35.8 7.9 1.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 KPI37185.1 - 2.3e-10 41.0 6.9 4.5e-05 24.1 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 KPI37185.1 - 2.3e-10 40.5 10.2 4.3e-10 39.6 7.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 KPI37185.1 - 4.2e-09 36.1 22.8 1.5e-06 27.9 8.8 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 KPI37185.1 - 4.3e-09 36.2 20.6 5.9e-07 29.4 7.7 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 KPI37185.1 - 2.4e-08 33.4 14.8 0.00029 20.5 1.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 KPI37185.1 - 3.6e-07 29.9 10.4 0.0002 21.4 1.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KPI37185.1 - 4.4e-07 29.4 16.4 0.0024 17.6 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 KPI37185.1 - 3e-06 27.4 10.2 0.00014 22.1 8.0 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 KPI37185.1 - 1.5e-05 25.3 10.2 0.0061 16.9 0.7 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 KPI37185.1 - 0.0025 18.1 15.1 0.27 11.6 1.9 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 KPI37185.1 - 0.0042 17.5 17.7 0.018 15.5 2.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 KPI37185.1 - 0.0046 17.4 13.1 0.44 11.1 1.3 2.8 2 1 0 2 2 2 2 4Fe-4S single cluster domain c-SKI_SMAD_bind PF08782.5 KPI37185.1 - 0.33 11.0 4.6 0.89 9.7 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain DUF3535 PF12054.3 KPI37186.1 - 1.6e-123 412.6 0.1 1.8e-122 409.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KPI37186.1 - 4.9e-77 258.6 0.0 1.7e-75 253.5 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KPI37186.1 - 2.4e-14 52.9 0.0 5.5e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 KPI37186.1 - 8.3e-12 44.1 11.3 0.0071 16.3 0.0 9.0 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.1 KPI37186.1 - 0.0011 19.2 16.6 0.0051 17.0 0.0 6.9 8 0 0 8 8 8 1 HEAT repeats HEAT_EZ PF13513.1 KPI37186.1 - 0.005 17.3 15.3 0.15 12.5 0.0 8.5 9 0 0 9 9 9 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KPI37186.1 - 0.11 12.9 0.5 6.1 7.2 0.0 3.9 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region V-ATPase_G PF03179.10 KPI37186.1 - 0.4 11.0 5.3 0.34 11.2 1.2 2.6 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Abhydrolase_6 PF12697.2 KPI37188.1 - 6e-27 94.9 1.2 9.8e-25 87.7 0.8 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI37188.1 - 4.6e-14 52.5 0.3 1e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI37188.1 - 6.7e-14 51.8 0.2 2.5e-13 50.0 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KPI37188.1 - 9e-09 35.0 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 KPI37188.1 - 0.0002 20.9 0.0 0.00034 20.1 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KPI37188.1 - 0.00083 18.6 0.2 0.017 14.3 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KPI37188.1 - 0.003 17.0 0.0 0.42 10.0 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.5 KPI37188.1 - 0.0072 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.8 KPI37188.1 - 0.066 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.9 KPI37188.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase Glyoxal_oxid_N PF07250.6 KPI37190.1 - 9.2e-18 64.1 0.1 1e-17 64.0 0.1 1.1 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus Abhydrolase_6 PF12697.2 KPI37191.1 - 3.6e-19 69.5 0.0 5.7e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI37191.1 - 1.3e-09 37.9 0.0 3.3e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI37191.1 - 0.0043 16.6 0.1 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI37191.1 - 0.051 12.7 0.0 15 4.7 0.0 2.9 3 0 0 3 3 3 0 Prolyl oligopeptidase family Peptidase_M22 PF00814.20 KPI37192.1 - 9.6e-59 199.0 0.0 1.2e-58 198.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family DUF3653 PF12375.3 KPI37192.1 - 0.083 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Phage protein Amidohydro_2 PF04909.9 KPI37194.1 - 6.9e-30 104.5 2.8 1.1e-29 103.9 1.9 1.3 1 1 0 1 1 1 1 Amidohydrolase Cupin_1 PF00190.17 KPI37195.1 - 1.4e-12 47.3 0.1 1.8e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Cupin MAPEG PF01124.13 KPI37196.1 - 8.6e-18 64.1 0.5 1.2e-17 63.6 0.4 1.2 1 0 0 1 1 1 1 MAPEG family SGL PF08450.7 KPI37197.1 - 0.0015 17.9 0.0 0.0038 16.6 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KPI37197.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Arylesterase RasGEF PF00617.14 KPI37199.1 - 3.3e-45 154.1 0.1 5.7e-45 153.3 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KPI37199.1 - 8.9e-13 48.2 0.2 2e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Ank_2 PF12796.2 KPI37200.1 - 1.1e-18 67.3 0.3 1.3e-17 63.9 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DIL PF01843.14 KPI37200.1 - 3.8e-18 65.2 2.8 2.8e-16 59.2 1.9 2.5 1 1 0 1 1 1 1 DIL domain Ank PF00023.25 KPI37200.1 - 5.2e-16 57.5 1.0 1.4e-06 27.8 0.0 3.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 KPI37200.1 - 2.8e-13 49.6 0.2 4e-08 33.2 0.1 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI37200.1 - 1.2e-09 37.4 1.9 0.002 18.1 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KPI37200.1 - 2e-09 37.6 0.1 4.8e-07 30.1 0.0 3.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Amidase PF01425.16 KPI37201.1 - 8.4e-62 209.4 3.9 7.9e-59 199.6 2.0 2.5 2 1 0 2 2 2 2 Amidase COesterase PF00135.23 KPI37202.1 - 4.3e-92 309.5 0.0 5.3e-92 309.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI37202.1 - 2.1e-06 27.4 0.0 3.1e-05 23.6 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold AHS2 PF02626.10 KPI37203.1 - 6.7e-75 251.8 0.0 1.6e-74 250.6 0.0 1.7 2 0 0 2 2 2 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 KPI37203.1 - 2.7e-55 186.9 0.0 4.8e-55 186.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KPI37203.1 - 7.4e-36 122.6 0.0 1.5e-35 121.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KPI37203.1 - 3.9e-30 103.9 0.0 1e-29 102.6 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain AHS1 PF02682.11 KPI37203.1 - 2.4e-24 85.9 0.0 4.5e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 ATP-grasp_4 PF13535.1 KPI37203.1 - 3.7e-13 49.6 0.0 6.6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KPI37203.1 - 9.1e-11 41.2 4.0 3e-10 39.6 2.4 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KPI37203.1 - 4.1e-10 38.9 0.0 8.2e-09 34.6 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KPI37203.1 - 2e-07 30.6 0.0 3.4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KPI37203.1 - 0.011 15.1 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 KPI37203.1 - 0.015 14.7 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 KPI37203.1 - 0.045 12.9 0.2 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain Amidase PF01425.16 KPI37204.1 - 1.3e-31 109.9 0.0 2.4e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Amidase DAO PF01266.19 KPI37206.1 - 1.1e-24 86.9 1.0 1.7e-24 86.4 0.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI37206.1 - 0.00015 21.7 1.2 0.00023 21.1 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KPI37206.1 - 0.0042 16.2 0.0 0.0042 16.2 0.0 2.2 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.19 KPI37206.1 - 0.0059 15.5 0.0 0.0059 15.5 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KPI37206.1 - 0.011 15.5 1.1 0.012 15.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1188 PF06690.6 KPI37206.1 - 0.015 14.4 0.1 0.32 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Pyr_redox_3 PF13738.1 KPI37206.1 - 0.022 14.8 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AAA_12 PF13087.1 KPI37207.1 - 7.2e-29 100.5 0.0 1.4e-28 99.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KPI37207.1 - 1e-12 48.1 0.0 1.7e-10 40.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KPI37207.1 - 6.6e-07 29.0 0.0 3.8e-05 23.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KPI37207.1 - 9.1e-07 28.5 0.0 9e-05 22.1 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KPI37207.1 - 0.00042 21.1 0.0 0.0041 17.9 0.0 2.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 KPI37207.1 - 0.00086 19.4 0.0 0.67 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KPI37207.1 - 0.0049 17.0 0.0 0.035 14.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KPI37207.1 - 0.0058 16.6 0.0 0.023 14.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.13 KPI37207.1 - 0.0061 16.1 0.0 0.14 11.7 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 KPI37207.1 - 0.01 15.0 0.0 0.057 12.6 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.1 KPI37207.1 - 0.013 15.3 0.0 0.049 13.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KPI37207.1 - 0.019 14.6 0.0 0.093 12.4 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA_5 PF07728.9 KPI37207.1 - 0.052 13.2 0.0 1.3 8.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.1 KPI37207.1 - 0.073 13.2 0.0 0.4 10.8 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_14 PF13173.1 KPI37207.1 - 0.088 12.7 0.0 0.84 9.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain TPR_10 PF13374.1 KPI37208.1 - 0.056 13.3 0.6 0.24 11.4 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat CorA PF01544.13 KPI37209.1 - 1.3e-08 34.2 0.7 2.1e-08 33.5 0.5 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SPC12 PF06645.8 KPI37209.1 - 0.98 9.2 4.3 0.59 9.9 1.2 1.9 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) ABM PF03992.11 KPI37210.1 - 0.00033 20.6 1.4 0.068 13.2 0.7 2.5 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase HET PF06985.6 KPI37211.1 - 5.4e-18 65.4 0.0 1.2e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fumble PF03630.9 KPI37213.1 - 4.7e-130 433.3 0.3 4.9e-129 430.0 0.2 2.0 1 1 0 1 1 1 1 Fumble DUF914 PF06027.7 KPI37214.1 - 1.1e-89 300.5 18.9 1.5e-89 300.2 13.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KPI37214.1 - 2e-06 27.8 10.2 2e-06 27.8 7.1 3.3 2 2 1 3 3 3 1 EamA-like transporter family MFS_1 PF07690.11 KPI37215.1 - 6.2e-07 28.4 50.0 3.6e-05 22.6 32.0 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily tRNA-synt_2b PF00587.20 KPI37216.1 - 1.6e-44 151.5 0.0 3e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KPI37216.1 - 5.2e-18 64.7 0.2 1.3e-17 63.5 0.2 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 KPI37216.1 - 1e-12 47.7 0.0 1.9e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 KPI37216.1 - 0.00027 20.7 0.0 0.00073 19.3 0.0 1.7 1 0 0 1 1 1 1 TGS domain Cytochrom_B561 PF03188.11 KPI37217.1 - 1.2e-18 67.3 1.2 1.2e-18 67.3 0.8 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 PIRT PF15099.1 KPI37217.1 - 0.15 11.2 0.1 0.15 11.2 0.0 2.7 2 2 1 3 3 3 0 Phosphoinositide-interacting protein family DUF1980 PF09323.5 KPI37217.1 - 0.15 11.7 0.1 1.8 8.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) DUF998 PF06197.8 KPI37217.1 - 0.3 10.3 21.4 2.5 7.3 7.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF998) PepSY_TM_1 PF13172.1 KPI37217.1 - 0.46 10.2 0.0 0.46 10.2 0.0 3.2 4 0 0 4 4 4 0 PepSY-associated TM helix AzlD PF05437.7 KPI37217.1 - 0.59 10.1 11.3 2.8 7.9 1.7 3.1 1 1 2 3 3 3 0 Branched-chain amino acid transport protein (AzlD) Amido_AtzD_TrzD PF09663.5 KPI37218.1 - 5.2e-94 314.8 3.1 7e-94 314.3 2.1 1.2 1 0 0 1 1 1 1 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) His_Phos_2 PF00328.17 KPI37219.1 - 8.2e-31 107.5 0.0 1.1e-30 107.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_S41 PF03572.13 KPI37221.1 - 4.5e-05 22.9 0.0 0.00011 21.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 EF-hand_1 PF00036.27 KPI37222.1 - 4.3e-25 85.0 18.8 2e-08 32.9 0.4 4.5 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 KPI37222.1 - 4.3e-23 81.2 2.5 1.1e-12 47.9 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KPI37222.1 - 8.4e-21 71.9 4.3 5.3e-05 22.7 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KPI37222.1 - 6.1e-20 69.5 11.5 1.3e-07 30.6 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KPI37222.1 - 5.7e-13 48.2 15.1 1.4e-05 24.5 0.7 4.6 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KPI37222.1 - 1.1e-05 25.4 0.0 0.012 15.6 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KPI37222.1 - 1.9e-05 24.3 7.8 0.017 14.8 0.2 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KPI37222.1 - 0.034 14.0 0.1 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain ATP-cone PF03477.11 KPI37222.1 - 0.053 13.9 0.3 0.13 12.7 0.1 1.6 2 0 0 2 2 2 0 ATP cone domain AMPKBI PF04739.10 KPI37223.1 - 1.3e-25 89.1 0.4 7.6e-25 86.7 0.0 2.4 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Exo_endo_phos PF03372.18 KPI37226.1 - 1.4e-10 41.5 0.1 2.3e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ETF_QO PF05187.8 KPI37227.1 - 5.3e-45 151.9 0.0 1.3e-44 150.6 0.0 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein-ubiquinone oxidoreductase NAD_binding_8 PF13450.1 KPI37227.1 - 2.9e-07 30.4 0.0 7.3e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI37227.1 - 1.7e-05 23.9 6.4 0.00027 19.9 0.2 2.5 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI37227.1 - 6.8e-05 21.8 0.6 0.0014 17.5 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KPI37227.1 - 9.6e-05 22.3 0.0 0.00016 21.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI37227.1 - 0.00013 21.1 0.0 0.00037 19.6 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KPI37227.1 - 0.00017 20.7 0.0 0.00032 19.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KPI37227.1 - 0.00022 19.8 0.2 0.00032 19.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 KPI37227.1 - 0.00057 19.6 0.1 0.0015 18.3 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KPI37227.1 - 0.00087 19.4 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI37227.1 - 0.0011 19.3 0.1 4.6 7.7 0.2 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KPI37227.1 - 0.0025 16.5 0.1 0.19 10.3 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.2 KPI37227.1 - 0.0048 16.0 0.1 0.01 14.9 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KPI37227.1 - 0.0058 15.5 0.1 0.0089 14.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Fer4_7 PF12838.2 KPI37227.1 - 0.01 16.1 0.7 0.046 14.1 0.5 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain GIDA PF01134.17 KPI37227.1 - 0.13 11.0 0.1 0.22 10.3 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A UreF PF01730.11 KPI37228.1 - 8.9e-11 42.1 0.1 1.2e-10 41.7 0.1 1.2 1 0 0 1 1 1 1 UreF DUF3433 PF11915.3 KPI37230.1 - 4.2e-39 132.6 8.6 9.2e-23 80.2 1.1 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) YjgP_YjgQ PF03739.9 KPI37230.1 - 1.8 7.1 8.5 1.1 7.9 2.8 2.6 2 1 0 2 2 2 0 Predicted permease YjgP/YjgQ family DUF1929 PF09118.6 KPI37231.1 - 1.3e-18 66.9 0.0 1.7e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.1 KPI37231.1 - 0.063 13.4 0.1 3.4 7.9 0.0 2.9 2 1 1 3 3 3 0 Kelch motif Ino80_Iec3 PF14612.1 KPI37232.1 - 4e-53 180.8 3.4 5.3e-53 180.4 2.4 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Dynamin_N PF00350.18 KPI37234.1 - 5.5e-31 107.6 0.0 1.3e-30 106.4 0.0 1.7 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KPI37234.1 - 5.1e-15 55.0 0.0 1e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 KPI37234.1 - 0.00044 20.1 0.0 0.0019 18.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KPI37234.1 - 0.0017 18.8 0.0 0.0062 17.0 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein GED PF02212.13 KPI37234.1 - 0.029 14.2 0.1 0.091 12.6 0.0 1.9 1 0 0 1 1 1 0 Dynamin GTPase effector domain FeoB_N PF02421.13 KPI37234.1 - 0.051 12.8 0.0 4.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_23 PF13476.1 KPI37234.1 - 0.38 11.0 2.6 0.32 11.2 0.3 2.1 2 1 0 2 2 2 0 AAA domain bZIP_1 PF00170.16 KPI37237.1 - 7.3e-07 29.0 8.4 9.8e-07 28.6 5.8 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KPI37237.1 - 3.7e-05 23.4 8.6 5.3e-05 22.9 6.0 1.2 1 0 0 1 1 1 1 Basic region leucine zipper TMF_TATA_bd PF12325.3 KPI37237.1 - 0.024 14.3 3.7 0.032 13.9 2.6 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.5 KPI37237.1 - 0.031 14.4 3.3 0.041 14.0 2.3 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Effector_1 PF04518.7 KPI37237.1 - 0.04 12.9 1.0 0.046 12.6 0.7 1.0 1 0 0 1 1 1 0 Effector from type III secretion system Glutaredoxin2_C PF04399.8 KPI37237.1 - 0.052 13.1 0.6 0.07 12.7 0.4 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain FlxA PF14282.1 KPI37237.1 - 0.068 13.1 4.6 0.15 12.0 3.2 1.6 1 1 0 1 1 1 0 FlxA-like protein bZIP_Maf PF03131.12 KPI37237.1 - 0.1 12.9 8.4 0.14 12.4 5.8 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor GvpL_GvpF PF06386.6 KPI37237.1 - 0.15 11.6 2.5 0.19 11.2 1.7 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4407 PF14362.1 KPI37237.1 - 0.51 9.2 4.1 0.62 8.9 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WD40 PF00400.27 KPI37241.1 - 3.3e-30 102.8 13.8 1.7e-07 30.8 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 KPI37241.1 - 0.0014 18.3 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KPI37241.1 - 0.016 13.3 2.2 0.11 10.6 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 3-dmu-9_3-mt PF06983.8 KPI37243.1 - 5.8e-23 81.4 0.0 1.4e-22 80.2 0.0 1.6 1 1 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase DLH PF01738.13 KPI37243.1 - 4.7e-15 55.4 0.0 4.4e-14 52.3 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KPI37243.1 - 1.4e-08 34.6 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI37243.1 - 0.0014 18.6 0.7 0.17 11.7 0.3 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_C13 PF01650.13 KPI37245.1 - 5.1e-43 147.2 0.0 6.8e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family IL6 PF00489.12 KPI37245.1 - 0.045 13.3 0.1 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family Ndufs5 PF10200.4 KPI37246.1 - 3.7e-05 23.6 0.1 4.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa UCR_hinge PF02320.11 KPI37246.1 - 0.018 14.9 1.1 0.03 14.2 0.7 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein DUF3128 PF11326.3 KPI37246.1 - 0.095 12.8 0.4 1.1 9.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) COX6B PF02297.12 KPI37246.1 - 0.19 11.8 0.3 0.19 11.8 0.2 1.9 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb UPF0203 PF05254.7 KPI37246.1 - 1.8 8.4 4.4 11 5.8 0.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Tautomerase_3 PF14832.1 KPI37247.1 - 8.5e-50 168.2 0.1 9.6e-50 168.1 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 KPI37247.1 - 0.14 11.7 0.0 0.53 9.9 0.0 2.0 1 1 1 2 2 2 0 Tautomerase enzyme Arrestin_C PF02752.17 KPI37250.1 - 6.5e-10 39.2 0.0 2.9e-08 33.9 0.0 2.6 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KPI37250.1 - 3e-05 23.8 0.4 0.00063 19.5 0.0 2.7 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain RXT2_N PF08595.6 KPI37251.1 - 6.3e-33 113.6 0.0 6.3e-33 113.6 0.0 3.5 2 1 2 4 4 4 1 RXT2-like, N-terminal DUF605 PF04652.11 KPI37251.1 - 0.68 9.2 17.9 1 8.6 12.4 1.3 1 0 0 1 1 1 0 Vta1 like Lambda_Kil PF06301.6 KPI37252.1 - 0.25 10.8 1.1 11 5.5 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage lambda Kil protein DLH PF01738.13 KPI37253.1 - 4.1e-27 94.8 0.0 4.8e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KPI37253.1 - 6.1e-08 32.5 0.0 7.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI37253.1 - 0.044 13.3 0.1 1 8.8 0.0 2.2 1 1 0 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.6 KPI37253.1 - 0.056 13.1 0.1 3.2 7.3 0.0 2.6 2 1 1 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 KPI37253.1 - 0.064 12.8 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_43 PF04616.9 KPI37254.1 - 5.3e-30 104.4 0.0 6.6e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 p450 PF00067.17 KPI37255.1 - 7e-40 136.9 0.0 9.4e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TMF_TATA_bd PF12325.3 KPI37257.1 - 0.27 10.9 3.8 0.32 10.7 1.8 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding p450 PF00067.17 KPI37259.1 - 2.6e-59 200.9 0.0 1.1e-58 198.9 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 CcmH PF03918.9 KPI37259.1 - 0.13 11.2 0.0 0.32 9.9 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C biogenesis protein UQ_con PF00179.21 KPI37260.1 - 5.4e-10 38.8 0.0 1.1e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KPI37260.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain DUF3454 PF11936.3 KPI37260.1 - 0.15 12.2 6.2 2.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3454) Fibrinogen_aC PF12160.3 KPI37261.1 - 2.5 7.6 9.0 0.4 10.1 2.0 2.5 2 0 0 2 2 2 0 Fibrinogen alpha C domain IFRD PF05004.8 KPI37265.1 - 3.6e-29 101.8 11.9 5.9e-29 101.1 8.3 1.3 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 KPI37265.1 - 0.02 15.1 9.5 0.41 10.9 0.4 3.0 2 1 0 3 3 3 0 HEAT repeats Corona_nucleoca PF00937.13 KPI37265.1 - 0.027 13.4 8.4 0.047 12.6 5.8 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein HEAT_EZ PF13513.1 KPI37265.1 - 0.93 10.0 4.5 8.3 7.0 0.9 3.4 2 1 2 4 4 4 0 HEAT-like repeat Methyltransf_24 PF13578.1 KPI37266.1 - 3.4e-11 43.9 0.2 7.4e-11 42.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.12 KPI37266.1 - 1.7e-06 27.2 0.0 2.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KPI37266.1 - 0.0033 17.9 0.5 0.0053 17.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain DUF1442 PF07279.6 KPI37266.1 - 0.032 13.3 0.0 0.072 12.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1442) VSP PF03302.8 KPI37267.1 - 0.0023 16.6 1.3 0.0042 15.7 0.9 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.6 KPI37267.1 - 0.0064 16.0 4.2 0.0064 16.0 2.9 2.1 2 0 0 2 2 2 1 Podoplanin DUF1049 PF06305.6 KPI37267.1 - 0.012 15.1 0.1 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF1206 PF06724.6 KPI37267.1 - 0.013 15.2 0.4 0.059 13.1 0.2 2.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) BatD PF13584.1 KPI37267.1 - 0.021 13.4 0.0 0.04 12.5 0.0 1.4 1 0 0 1 1 1 0 Oxygen tolerance DUF4448 PF14610.1 KPI37267.1 - 0.048 13.1 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) RIC3 PF15361.1 KPI37267.1 - 0.17 12.1 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 MtrF PF09472.5 KPI37267.1 - 0.51 9.6 2.4 0.54 9.5 0.5 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SKG6 PF08693.5 KPI37267.1 - 1.1 8.6 3.9 0.3 10.4 0.5 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain adh_short PF00106.20 KPI37268.1 - 4.9e-13 49.3 0.3 8.3e-13 48.5 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI37268.1 - 3e-06 27.2 0.1 4.2e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KPI37268.1 - 4.3e-06 26.8 0.3 8.6e-06 25.8 0.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KPI37268.1 - 0.0014 18.2 0.4 0.0028 17.3 0.3 1.6 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KPI37268.1 - 0.014 14.1 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sar8_2 PF03058.9 KPI37268.1 - 0.045 14.0 0.3 0.094 13.0 0.1 1.7 2 0 0 2 2 2 0 Sar8.2 family DUF1776 PF08643.5 KPI37268.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pal1 PF08316.6 KPI37269.1 - 4e-49 166.6 2.8 8.2e-49 165.6 0.3 2.5 2 0 0 2 2 2 1 Pal1 cell morphology protein Atg14 PF10186.4 KPI37270.1 - 0.097 11.5 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NotI PF12183.3 KPI37271.1 - 0.052 12.6 1.5 0.062 12.3 1.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease NotI YrvL PF14184.1 KPI37271.1 - 0.27 11.0 4.5 0.31 10.8 3.1 1.1 1 0 0 1 1 1 0 Regulatory protein YrvL FSH1 PF03959.8 KPI37272.1 - 1.1e-26 93.6 0.0 1.4e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KPI37272.1 - 0.0019 17.6 0.1 0.012 15.0 0.0 1.9 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KPI37272.1 - 0.0029 17.5 4.6 0.022 14.6 3.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Imm45 PF15603.1 KPI37272.1 - 0.083 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 45 LtrA PF06772.6 KPI37273.1 - 7.3e-21 74.4 11.1 1.1e-20 73.8 7.7 1.3 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Rdx PF10262.4 KPI37273.1 - 0.12 12.4 0.0 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 Rdx family YfhO PF09586.5 KPI37273.1 - 1.2 7.1 9.1 0.56 8.1 4.3 1.9 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DUF4366 PF14283.1 KPI37274.1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) SSP160 PF06933.6 KPI37274.1 - 0.11 10.4 17.2 0.15 10.0 12.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SKG6 PF08693.5 KPI37274.1 - 0.5 9.7 0.0 0.5 9.7 0.0 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Sporozoite_P67 PF05642.6 KPI37274.1 - 1.6 6.5 6.8 1.7 6.4 4.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Activin_recp PF01064.18 KPI37274.1 - 4 8.1 10.3 16 6.1 7.0 2.0 1 1 1 2 2 2 0 Activin types I and II receptor domain Prenylcys_lyase PF07156.9 KPI37275.1 - 1.4e-30 106.4 0.0 5e-29 101.3 0.0 2.1 1 1 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.19 KPI37275.1 - 7.5e-13 48.3 0.0 1.7e-12 47.1 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KPI37275.1 - 1.2e-10 41.2 0.2 3.1e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI37275.1 - 1.1e-08 34.3 0.1 4.3e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KPI37275.1 - 4.5e-05 23.2 0.1 0.0022 17.7 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KPI37275.1 - 0.0091 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI37275.1 - 0.024 15.0 0.2 0.11 12.9 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI37275.1 - 0.038 14.0 0.0 0.1 12.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI37275.1 - 0.044 12.2 0.0 0.08 11.4 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein RE_TdeIII PF09520.5 KPI37275.1 - 0.063 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII Lipase_GDSL_2 PF13472.1 KPI37276.1 - 3.9e-12 46.6 0.1 6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Gar1 PF04410.9 KPI37278.1 - 7.7e-37 126.1 0.4 1.1e-36 125.5 0.3 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Per1 PF04080.8 KPI37279.1 - 1.8e-94 316.0 15.9 1.8e-92 309.5 11.0 2.0 1 1 0 1 1 1 1 Per1-like Glyco_hydro_3 PF00933.16 KPI37282.1 - 2.7e-91 305.6 0.0 4.1e-91 305.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KPI37282.1 - 3.8e-39 134.5 1.3 1e-37 129.8 0.0 2.9 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KPI37282.1 - 2.8e-10 39.9 0.0 6.1e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain ABC1 PF03109.11 KPI37283.1 - 3.7e-34 117.2 0.0 8.7e-34 116.0 0.0 1.7 1 0 0 1 1 1 1 ABC1 family MaoC_dehydratas PF01575.14 KPI37287.1 - 1.7e-25 88.8 0.0 3.1e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KPI37287.1 - 2.2e-07 30.6 0.0 1.4e-05 24.8 0.0 2.5 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase ZZ PF00569.12 KPI37288.1 - 2e-24 84.8 50.4 2.5e-11 42.9 4.6 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type zf-dskA_traR PF01258.12 KPI37288.1 - 0.24 11.1 5.4 5.8 6.7 0.0 3.7 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger PP-binding PF00550.20 KPI37289.1 - 5.8e-11 42.5 0.4 7.9e-11 42.0 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KPI37289.1 - 1.3e-06 28.3 0.2 1.9e-06 27.8 0.2 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 KPI37289.1 - 0.055 13.5 0.2 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) adh_short PF00106.20 KPI37291.1 - 3.8e-12 46.4 0.0 5.1e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI37291.1 - 1.2e-05 25.1 0.0 1.7e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SHMT PF00464.14 KPI37291.1 - 0.16 10.2 0.0 0.22 9.8 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Fungal_trans PF04082.13 KPI37292.1 - 9.5e-11 41.0 0.0 1.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Homeobox_KN PF05920.6 KPI37294.1 - 1.1e-14 53.7 0.6 2.8e-14 52.5 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.11 KPI37294.1 - 5.6e-06 26.0 0.1 1.4e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.1 KPI37294.1 - 8e-05 22.6 24.6 0.0092 16.2 0.9 4.6 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI37294.1 - 0.0003 20.9 15.1 0.059 13.7 0.6 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type Homeobox PF00046.24 KPI37294.1 - 0.00048 19.6 0.2 0.0011 18.5 0.1 1.7 1 0 0 1 1 1 1 Homeobox domain HA PF03457.9 KPI37294.1 - 0.027 14.5 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 Helicase associated domain Sugar_tr PF00083.19 KPI37295.1 - 5.4e-76 255.9 20.7 6.7e-76 255.6 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI37295.1 - 4.3e-18 65.1 21.1 4.3e-18 65.1 14.6 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily UPF0233 PF06781.7 KPI37295.1 - 0.8 9.3 0.0 0.8 9.3 0.0 4.1 6 0 0 6 6 6 0 Uncharacterised protein family (UPF0233) Stm1_N PF09598.5 KPI37296.1 - 3.7e-13 49.9 1.7 3.7e-13 49.9 1.2 4.0 5 1 0 5 5 5 1 Stm1 SET PF00856.23 KPI37297.1 - 1.9e-16 60.8 0.0 9.8e-16 58.4 0.0 2.2 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 KPI37297.1 - 1.5e-05 24.9 0.1 1.5e-05 24.9 0.1 2.4 3 0 0 3 3 3 1 Rubisco LSMT substrate-binding DUF1045 PF06299.7 KPI37297.1 - 0.024 14.2 3.6 0.11 12.1 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) DUF4054 PF13262.1 KPI37297.1 - 0.043 14.0 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) MRP-S33 PF08293.6 KPI37297.1 - 0.099 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 SepQ PF06622.6 KPI37297.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 SepQ protein RRM_1 PF00076.17 KPI37298.1 - 1.1e-18 66.5 0.0 1e-12 47.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI37298.1 - 9.2e-17 60.7 0.0 1.8e-10 40.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI37298.1 - 3.3e-07 30.0 0.0 0.0015 18.3 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KPI37298.1 - 0.0081 15.9 0.0 0.022 14.4 0.0 1.8 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF4169 PF13770.1 KPI37298.1 - 0.021 14.7 1.0 0.021 14.7 0.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4169) DUF3123 PF11321.3 KPI37299.1 - 0.053 13.7 1.8 0.07 13.4 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3123) 2OG-FeII_Oxy_2 PF13532.1 KPI37301.1 - 1.7e-33 116.0 0.0 2.5e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 KPI37301.1 - 0.00021 21.1 7.1 0.0014 18.5 4.9 2.1 1 1 0 1 1 1 1 GRF zinc finger 2OG-FeII_Oxy PF03171.15 KPI37301.1 - 0.015 15.5 0.0 0.066 13.5 0.0 2.1 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Btz PF09405.5 KPI37302.1 - 8.7e-21 74.3 4.2 2.1e-20 73.0 2.9 1.6 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding adh_short PF00106.20 KPI37304.1 - 3.2e-26 92.2 0.2 4.7e-26 91.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI37304.1 - 2.9e-11 43.3 0.1 6.5e-11 42.2 0.1 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI37304.1 - 4.5e-09 36.4 0.0 9.1e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF664 PF04978.7 KPI37304.1 - 0.022 15.0 0.1 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF664) DUF1776 PF08643.5 KPI37304.1 - 0.036 13.2 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KPI37304.1 - 0.076 13.0 0.1 1 9.3 0.0 2.1 2 0 0 2 2 2 0 NADH(P)-binding BATS PF06968.8 KPI37304.1 - 0.089 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain Eno-Rase_NADH_b PF12242.3 KPI37304.1 - 0.1 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KPI37305.1 - 9.1e-21 74.1 0.0 1.2e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI37305.1 - 0.0025 17.8 0.0 0.051 13.5 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding Peptidase_M28 PF04389.12 KPI37306.1 - 8.7e-36 123.3 0.0 1.4e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KPI37306.1 - 1.8e-19 69.2 0.6 3.7e-19 68.2 0.4 1.6 1 0 0 1 1 1 1 PA domain HgmA PF04209.8 KPI37307.1 - 1.7e-114 382.5 0.1 2.1e-114 382.2 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Sec39 PF08314.6 KPI37308.1 - 2.1e-117 392.9 7.8 6e-114 381.5 1.0 2.1 1 1 1 2 2 2 2 Secretory pathway protein Sec39 Enolase_C PF00113.17 KPI37308.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain CoA_transf_3 PF02515.12 KPI37309.1 - 3.1e-54 183.1 0.1 5.4e-54 182.3 0.1 1.4 1 0 0 1 1 1 1 CoA-transferase family III LamB_YcsF PF03746.11 KPI37310.1 - 2.6e-54 183.9 0.0 1.1e-53 181.7 0.0 1.7 1 1 0 1 1 1 1 LamB/YcsF family Peptidase_S24 PF00717.18 KPI37311.1 - 5.5e-08 32.3 0.0 1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Sarcolipin PF05366.6 KPI37311.1 - 0.12 11.8 1.6 0.29 10.5 0.1 2.3 2 0 0 2 2 2 0 Sarcolipin 4HBT PF03061.17 KPI37312.1 - 0.0066 16.5 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily EVE PF01878.13 KPI37313.1 - 6.8e-14 52.1 0.0 8.3e-14 51.8 0.0 1.0 1 0 0 1 1 1 1 EVE domain Nitroreductase PF00881.19 KPI37314.1 - 6.8e-05 22.7 0.0 0.0001 22.1 0.0 1.3 1 1 0 1 1 1 1 Nitroreductase family Adeno_hexon PF01065.14 KPI37315.1 - 0.16 10.7 0.2 0.19 10.5 0.2 1.0 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain DUF2315 PF10231.4 KPI37316.1 - 0.22 11.3 9.2 3.2 7.6 4.1 3.4 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2315) NPV_P10 PF05531.7 KPI37316.1 - 4.9 7.4 11.3 2.1 8.6 1.0 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Fungal_trans_2 PF11951.3 KPI37317.1 - 5.5e-06 25.2 0.8 1.1e-05 24.2 0.5 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain HWE_HK PF07536.9 KPI37317.1 - 0.034 14.5 0.6 0.11 12.9 0.4 1.8 1 0 0 1 1 1 0 HWE histidine kinase EPL1 PF10513.4 KPI37318.1 - 2.9e-26 92.6 0.2 2.9e-26 92.6 0.2 2.6 2 1 0 2 2 2 1 Enhancer of polycomb-like DUF4404 PF14357.1 KPI37318.1 - 0.3 11.5 6.9 0.34 11.3 0.2 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) p450 PF00067.17 KPI37319.1 - 3.8e-61 207.0 0.0 5.2e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Steroid_dh PF02544.11 KPI37320.1 - 3.1e-08 33.5 0.5 3.8e-08 33.2 0.4 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF3317 PF11779.3 KPI37320.1 - 0.19 11.1 5.2 0.43 10.0 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3317) YhhN PF07947.9 KPI37320.1 - 0.32 10.3 4.1 0.44 9.9 2.9 1.3 1 1 0 1 1 1 0 YhhN-like protein MIP PF00230.15 KPI37321.1 - 7.1e-31 107.4 7.5 9.7e-31 106.9 5.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF1014 PF06244.7 KPI37322.1 - 1.1e-17 64.3 9.2 1.1e-16 61.1 6.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Gluconate_2-dh3 PF13618.1 KPI37322.1 - 2.3 8.3 14.8 2.3 8.3 9.4 1.6 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Barttin PF15462.1 KPI37322.1 - 2.8 7.5 6.5 3.6 7.1 4.5 1.2 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Spore_coat_CotO PF14153.1 KPI37322.1 - 5.8 6.3 9.5 7.8 5.8 6.6 1.4 1 0 0 1 1 1 0 Spore coat protein CotO DUF4407 PF14362.1 KPI37322.1 - 6.5 5.6 13.5 8.3 5.2 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_12 PF13424.1 KPI37323.1 - 6.2e-20 70.9 0.3 3.3e-08 33.3 0.0 4.5 4 1 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KPI37323.1 - 3.8e-11 42.4 0.0 0.00028 20.4 0.0 4.1 4 1 0 4 4 4 2 TPR repeat NB-ARC PF00931.17 KPI37323.1 - 1.7e-10 40.2 0.0 3.3e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.12 KPI37323.1 - 1.2e-09 37.2 4.1 0.1 12.5 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 KPI37323.1 - 4.9e-08 32.6 0.8 0.00092 19.0 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KPI37323.1 - 8.6e-07 29.2 0.0 0.00034 20.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KPI37323.1 - 1.5e-06 27.5 1.4 1.2 8.8 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KPI37323.1 - 1.6e-06 28.2 1.0 7.5 7.4 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KPI37323.1 - 2.7e-05 24.7 5.8 0.11 13.1 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KPI37323.1 - 6e-05 22.5 3.2 2.5 8.0 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 KPI37323.1 - 0.0008 19.6 0.6 0.062 13.7 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KPI37323.1 - 0.0016 18.0 0.4 23 5.0 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KPI37323.1 - 0.0037 17.6 0.2 1.4 9.5 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.1 KPI37323.1 - 0.0079 16.3 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KPI37323.1 - 0.04 13.3 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_17 PF13431.1 KPI37323.1 - 0.05 13.8 3.4 9.2 6.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Resolvase PF00239.16 KPI37323.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Resolvase, N terminal domain AAA_14 PF13173.1 KPI37323.1 - 0.15 11.9 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain BCS1_N PF08740.6 KPI37324.1 - 3.9e-22 78.7 0.1 3.9e-22 78.7 0.1 2.5 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 KPI37324.1 - 1.5e-13 51.0 0.0 1.2e-05 25.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KPI37324.1 - 0.00012 22.8 0.3 0.0029 18.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KPI37324.1 - 0.00024 20.2 0.0 0.00044 19.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KPI37324.1 - 0.0013 18.4 0.0 0.005 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KPI37324.1 - 0.0047 17.0 0.0 0.079 13.0 0.0 2.9 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.12 KPI37324.1 - 0.0076 15.6 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KPI37324.1 - 0.03 13.7 0.0 0.084 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KPI37324.1 - 0.046 13.3 2.6 0.58 9.6 1.8 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KPI37324.1 - 0.049 13.6 1.6 1.8 8.5 0.0 3.1 2 1 1 3 3 3 0 AAA ATPase domain AAA_33 PF13671.1 KPI37324.1 - 0.12 12.2 1.8 0.39 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Copper-bind PF00127.15 KPI37326.1 - 0.16 12.2 0.5 0.23 11.7 0.3 1.4 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Med31 PF05669.7 KPI37327.1 - 5.4e-27 93.5 0.4 7.6e-27 93.0 0.3 1.2 1 0 0 1 1 1 1 SOH1 HlyIII PF03006.15 KPI37330.1 - 1.7e-57 194.3 19.9 2.1e-57 194.1 13.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4231 PF14015.1 KPI37330.1 - 1.1 9.2 5.9 0.47 10.4 0.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF4231) Abhydrolase_1 PF00561.15 KPI37331.1 - 9.5e-12 44.9 0.0 1.6e-11 44.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI37331.1 - 1.1e-06 28.7 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4440 PF14534.1 KPI37332.1 - 1.9e-08 34.4 0.0 2.4e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Fungal_trans PF04082.13 KPI37334.1 - 6.4e-34 117.0 0.0 9.5e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PTR2 PF00854.16 KPI37335.1 - 2.9e-40 138.1 16.9 7.3e-37 127.0 11.7 2.7 1 1 0 1 1 1 1 POT family DUF2561 PF10812.3 KPI37335.1 - 0.062 12.8 1.3 33 4.0 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2561) XRCC4 PF06632.7 KPI37337.1 - 1.3e-08 34.0 7.3 1.8e-08 33.6 5.1 1.3 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 SPX PF03105.14 KPI37337.1 - 0.0023 17.7 10.5 0.003 17.3 7.3 1.3 1 0 0 1 1 1 1 SPX domain GTPase_Cys_C PF12631.2 KPI37337.1 - 0.24 11.8 1.5 1.1 9.7 0.4 2.4 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Fungal_trans_2 PF11951.3 KPI37338.1 - 3.3e-05 22.6 0.6 6.5e-05 21.6 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain HAD_2 PF13419.1 KPI37339.1 - 2.7e-27 96.1 0.0 3.2e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KPI37339.1 - 0.00043 19.9 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KPI37339.1 - 0.093 13.1 0.0 0.16 12.3 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase LCAT PF02450.10 KPI37340.1 - 9e-86 288.2 0.1 1.2e-85 287.8 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase cobW PF02492.14 KPI37342.1 - 2.8e-45 153.9 0.2 3.8e-45 153.5 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 KPI37342.1 - 0.00024 20.5 0.8 0.00094 18.6 0.5 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 KPI37342.1 - 0.0007 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase MMR_HSR1 PF01926.18 KPI37342.1 - 0.00075 19.4 0.1 0.0029 17.5 0.0 2.0 1 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KPI37342.1 - 0.0014 18.2 0.5 0.011 15.2 0.3 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 KPI37342.1 - 0.0018 18.6 0.0 0.0029 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 KPI37342.1 - 0.0069 15.8 0.1 0.013 14.8 0.1 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.22 KPI37342.1 - 0.0079 16.4 0.1 0.036 14.3 0.0 2.0 2 0 0 2 2 2 1 ABC transporter CobW_C PF07683.9 KPI37342.1 - 0.0095 15.6 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_5 PF07728.9 KPI37342.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KPI37342.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 KPI37342.1 - 0.018 14.9 0.0 0.055 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KPI37342.1 - 0.021 14.3 0.1 0.072 12.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF258 PF03193.11 KPI37342.1 - 0.023 13.8 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 KPI37342.1 - 0.023 14.9 0.3 0.049 13.9 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KPI37342.1 - 0.025 14.3 0.1 0.062 13.0 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KPI37342.1 - 0.035 14.2 0.2 0.097 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KPI37342.1 - 0.065 11.9 1.1 0.64 8.7 0.2 2.7 2 1 0 2 2 2 0 ArgK protein MobB PF03205.9 KPI37342.1 - 0.078 12.6 0.1 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KPI37342.1 - 0.096 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Miro PF08477.8 KPI37342.1 - 0.11 13.0 0.5 1.8 9.1 0.0 2.8 3 1 0 3 3 3 0 Miro-like protein Zeta_toxin PF06414.7 KPI37342.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.17 KPI37342.1 - 0.13 11.6 0.2 0.31 10.4 0.1 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 KPI37342.1 - 0.13 12.0 0.0 0.85 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 KPI37343.1 - 3.2e-73 246.1 0.0 4.4e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI37343.1 - 4.6e-36 124.2 0.0 1.2e-35 122.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI37343.1 - 4.5e-06 25.8 2.3 0.51 9.2 0.0 3.5 4 0 0 4 4 4 3 Kinase-like APH PF01636.18 KPI37343.1 - 0.00044 20.0 0.1 0.31 10.7 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family MFS_1 PF07690.11 KPI37344.1 - 1.5e-15 56.7 6.9 1.5e-15 56.7 4.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily YtxH PF12732.2 KPI37344.1 - 0.4 11.0 2.5 0.51 10.7 0.2 2.3 2 0 0 2 2 2 0 YtxH-like protein DUF2681 PF10883.3 KPI37344.1 - 2.1 8.6 4.9 28 5.0 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) EMP24_GP25L PF01105.19 KPI37345.1 - 1.1e-50 171.9 0.0 1.2e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PUL PF08324.6 KPI37345.1 - 0.059 12.1 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 PUL domain F_bP_aldolase PF01116.15 KPI37346.1 - 7.5e-81 271.3 0.0 8.5e-81 271.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.13 KPI37346.1 - 0.0052 15.8 0.0 0.01 14.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotriesterase family Fasciclin PF02469.17 KPI37347.1 - 8.7e-36 122.7 2.7 2.5e-19 69.5 0.4 2.2 2 0 0 2 2 2 2 Fasciclin domain Transferase PF02458.10 KPI37349.1 - 3.5e-10 38.9 0.0 1.1e-09 37.2 0.0 1.8 2 1 0 2 2 2 1 Transferase family PAF-AH_p_II PF03403.8 KPI37350.1 - 8.6e-39 132.8 0.0 2.7e-33 114.7 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KPI37350.1 - 6.3e-13 48.7 0.1 1.4e-12 47.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI37350.1 - 3.8e-08 33.5 0.0 6.3e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KPI37350.1 - 1.8e-07 30.2 0.2 2.4e-06 26.6 0.1 2.1 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KPI37350.1 - 0.00045 19.1 0.0 0.0012 17.7 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 KPI37350.1 - 0.00096 18.9 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KPI37350.1 - 0.0032 17.0 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KPI37350.1 - 0.036 13.6 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.7 KPI37350.1 - 0.065 11.7 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) WD40_alt PF14077.1 KPI37350.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif HAUS6_N PF14661.1 KPI37351.1 - 7.8e-35 120.4 1.2 1.6e-34 119.3 0.9 1.5 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus SGL PF08450.7 KPI37352.1 - 4.3e-26 91.7 0.0 7.5e-26 90.9 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 KPI37352.1 - 0.0098 15.8 6.8 0.23 11.4 0.1 3.8 4 1 0 4 4 4 2 NHL repeat Arylesterase PF01731.15 KPI37352.1 - 0.013 15.4 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 Arylesterase Acetyltransf_1 PF00583.19 KPI37353.1 - 1.9e-18 66.2 0.0 2.9e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KPI37353.1 - 1.8e-11 43.6 0.0 3e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KPI37353.1 - 7.6e-11 42.0 0.0 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI37353.1 - 1.4e-09 38.0 0.0 2.1e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KPI37353.1 - 1.8e-09 37.9 0.0 2.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KPI37353.1 - 3.1e-05 23.9 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KPI37353.1 - 5.1e-05 23.1 0.0 9.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 KPI37353.1 - 0.00052 18.9 0.1 0.00072 18.4 0.1 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.1 KPI37353.1 - 0.017 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 KPI37353.1 - 0.018 15.0 0.0 0.027 14.4 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain IQ PF00612.22 KPI37354.1 - 0.0068 15.9 2.7 0.021 14.4 1.9 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Malate_DH PF12434.3 KPI37354.1 - 1.3 8.7 8.8 1.8 8.3 0.4 3.3 3 0 0 3 3 3 0 Malate dehydrogenase enzyme BTB PF00651.26 KPI37356.1 - 8.2e-09 35.4 0.0 2e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain ADH_N PF08240.7 KPI37357.1 - 1.6e-24 85.7 1.2 3.5e-24 84.6 0.3 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI37357.1 - 2.8e-21 75.4 0.3 1.2e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI37357.1 - 6.8e-07 30.2 0.0 1.3e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Gti1_Pac2 PF09729.4 KPI37358.1 - 4.4e-41 140.5 2.3 2.7e-39 134.7 0.1 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Mem_trans PF03547.13 KPI37359.1 - 0.15 10.3 0.0 0.19 9.9 0.0 1.0 1 0 0 1 1 1 0 Membrane transport protein RCR PF12273.3 KPI37359.1 - 4.3 7.8 6.6 13 6.3 4.6 2.1 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red FixQ PF05545.6 KPI37359.1 - 6.2 6.5 11.0 14 5.3 7.6 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ HNH PF01844.18 KPI37360.1 - 0.0056 16.5 2.5 0.0056 16.5 1.7 1.8 2 0 0 2 2 2 1 HNH endonuclease WPP PF13943.1 KPI37360.1 - 0.056 13.6 0.3 0.1 12.7 0.2 1.4 1 0 0 1 1 1 0 WPP domain adh_short PF00106.20 KPI37362.1 - 1.6e-27 96.4 0.0 2.4e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI37362.1 - 4.3e-17 62.6 0.0 5.6e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI37362.1 - 1.4e-09 37.8 0.0 2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI37362.1 - 3.1e-06 27.3 0.0 5.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KPI37362.1 - 0.0013 17.9 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 KPI37362.1 - 0.0015 17.9 0.0 0.0028 17.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Trm56 PF01994.11 KPI37362.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 tRNA ribose 2'-O-methyltransferase, aTrm56 Glyco_hydro_108 PF05838.7 KPI37362.1 - 0.097 12.7 0.0 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase 108 IU_nuc_hydro PF01156.14 KPI37364.1 - 9.5e-52 176.1 0.0 1.3e-49 169.1 0.0 2.1 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Cutinase PF01083.17 KPI37365.1 - 7.7e-20 71.3 0.0 1.1e-18 67.6 0.0 2.0 2 0 0 2 2 2 1 Cutinase VIT1 PF01988.14 KPI37366.1 - 1.5e-62 210.8 1.7 1.7e-62 210.6 1.2 1.0 1 0 0 1 1 1 1 VIT family ATP-synt_E PF05680.7 KPI37366.1 - 0.56 10.2 1.9 2.4 8.1 0.1 2.3 2 0 0 2 2 2 0 ATP synthase E chain DUF3464 PF11947.3 KPI37366.1 - 0.7 9.3 3.8 1.6 8.2 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) SRPRB PF09439.5 KPI37367.1 - 1.7e-26 92.5 0.0 4.3e-25 87.9 0.0 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 KPI37367.1 - 4e-08 32.7 0.0 0.00017 20.8 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KPI37367.1 - 1.3e-07 31.6 0.0 2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KPI37367.1 - 2.9e-07 30.0 0.0 9e-06 25.2 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KPI37367.1 - 0.004 16.3 0.0 0.0073 15.4 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 KPI37367.1 - 0.012 15.2 0.0 0.38 10.2 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 KPI37367.1 - 0.014 15.2 0.0 1.2 8.8 0.0 2.4 1 1 0 2 2 2 0 Dynamin family AAA_16 PF13191.1 KPI37367.1 - 0.028 14.3 0.1 0.059 13.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 KPI37367.1 - 0.043 13.1 0.0 9.5 5.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 KPI37367.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Septin PF00735.13 KPI37367.1 - 0.15 11.0 0.0 0.52 9.2 0.0 1.8 2 1 0 2 2 2 0 Septin FAD_binding_3 PF01494.14 KPI37368.1 - 1e-12 47.7 0.1 7e-06 25.3 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_9 PF13454.1 KPI37368.1 - 0.00098 18.9 0.2 0.0042 16.8 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KPI37368.1 - 0.0013 17.7 0.1 0.0067 15.3 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI37368.1 - 0.014 15.4 0.0 0.045 13.7 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HD_3 PF13023.1 KPI37369.1 - 3.8e-44 150.3 0.0 5.2e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.17 KPI37369.1 - 0.058 13.4 0.0 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 HD domain SCP2 PF02036.12 KPI37370.1 - 1.1e-23 83.4 0.3 1.2e-23 83.2 0.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KPI37370.1 - 2.3e-06 27.5 0.2 2.7e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal MFS_1 PF07690.11 KPI37372.1 - 1.3e-43 149.0 40.9 3.1e-43 147.8 27.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI37372.1 - 3.2e-11 42.4 24.2 3.2e-10 39.1 16.8 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1673 PF07895.6 KPI37372.1 - 1.5 8.3 4.3 64 2.9 2.9 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) DUF755 PF05501.6 KPI37372.1 - 1.8 8.6 9.9 3.9 7.5 6.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) PGAP1 PF07819.8 KPI37373.1 - 2.8e-06 27.1 0.0 5.8e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KPI37373.1 - 3.6e-06 27.0 0.3 4.5e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KPI37373.1 - 3.5e-05 23.2 0.0 6.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KPI37373.1 - 6.5e-05 22.7 0.1 0.0001 22.0 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI37373.1 - 0.00095 18.7 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 KPI37373.1 - 0.0012 17.8 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 KPI37373.1 - 0.0048 16.0 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) PAS_3 PF08447.6 KPI37374.1 - 4.1e-10 39.6 0.0 3.8e-08 33.3 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 KPI37374.1 - 6.1e-09 36.1 0.0 6.3e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KPI37374.1 - 1.2e-05 25.3 0.0 0.011 15.7 0.0 3.0 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 KPI37374.1 - 1.8e-05 24.5 0.0 0.045 13.5 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 KPI37374.1 - 2.3e-05 24.2 0.0 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 PAS domain HTH_32 PF13565.1 KPI37375.1 - 0.0014 19.4 8.7 0.16 12.8 0.4 2.7 1 1 1 2 2 2 2 Homeodomain-like domain Myb_DNA-bind_6 PF13921.1 KPI37375.1 - 0.028 14.5 0.7 4 7.6 0.1 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KPI37375.1 - 0.028 14.4 0.1 9.4 6.3 0.0 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain EthD PF07110.6 KPI37376.1 - 0.001 19.9 0.9 0.61 11.0 0.1 2.8 2 2 0 2 2 2 2 EthD domain DUF4286 PF14114.1 KPI37376.1 - 0.021 15.0 0.0 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) Acyltransferase PF01553.16 KPI37377.1 - 0.00057 19.3 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Abhydrolase_6 PF12697.2 KPI37380.1 - 1.7e-05 24.8 0.0 0.00015 21.7 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family NB-ARC PF00931.17 KPI37380.1 - 3.4e-05 22.8 0.0 5.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KPI37380.1 - 4.1e-05 23.6 0.1 0.00019 21.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KPI37380.1 - 0.00042 20.4 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain PGAP1 PF07819.8 KPI37380.1 - 0.0037 16.8 0.0 0.0079 15.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KPI37380.1 - 0.013 14.7 0.0 0.033 13.4 0.0 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KPI37380.1 - 0.025 14.3 0.0 0.065 12.9 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family NACHT PF05729.7 KPI37380.1 - 0.038 13.6 0.0 1.2 8.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 KPI37380.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Pkinase PF00069.20 KPI37381.1 - 1.1e-40 139.4 0.0 1.2e-24 86.9 0.1 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KPI37381.1 - 2.3e-14 53.1 0.4 9.5e-10 37.9 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase adh_short PF00106.20 KPI37382.1 - 2.6e-22 79.5 0.2 4.1e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI37382.1 - 1e-09 38.5 0.0 1.5e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI37382.1 - 1.3e-07 31.5 0.1 2.3e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI37382.1 - 0.0022 18.0 0.1 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 KPI37382.1 - 0.028 14.0 0.1 0.058 13.0 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KPI37382.1 - 0.076 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4235 PF14019.1 KPI37382.1 - 0.3 10.9 2.5 19 5.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4235) EthD PF07110.6 KPI37385.1 - 3.6e-16 59.8 0.1 4.6e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 EthD domain DUF659 PF04937.10 KPI37385.1 - 0.0062 16.0 0.0 0.0093 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) ATP-grasp PF02222.17 KPI37385.1 - 0.064 12.6 0.0 0.082 12.2 0.0 1.1 1 0 0 1 1 1 0 ATP-grasp domain Ldh_1_C PF02866.13 KPI37385.1 - 0.095 12.4 0.0 8.8 6.0 0.0 2.1 1 1 1 2 2 2 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain MmlI PF09448.5 KPI37385.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase BAR_2 PF10455.4 KPI37386.1 - 4.2e-43 147.3 6.0 1e-41 142.7 4.2 2.2 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KPI37386.1 - 8.2e-11 41.8 4.3 8.8e-05 22.1 1.2 2.2 2 0 0 2 2 2 2 BAR domain NAM-associated PF14303.1 KPI37386.1 - 0.0089 16.3 4.2 0.016 15.5 2.9 1.4 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain F-protein PF00469.15 KPI37386.1 - 1.6 8.0 4.4 2.8 7.2 3.0 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef SURF4 PF02077.10 KPI37387.1 - 4.2e-86 288.6 6.9 4.9e-86 288.4 4.8 1.0 1 0 0 1 1 1 1 SURF4 family UPF0029 PF01205.14 KPI37388.1 - 1.7e-27 95.2 0.0 2.5e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KPI37388.1 - 6.9e-08 32.3 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 KPI37388.1 - 0.084 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Peptidase_M76 PF09768.4 KPI37390.1 - 5.3e-60 201.8 4.4 6.2e-60 201.5 3.0 1.0 1 0 0 1 1 1 1 Peptidase M76 family DUF678 PF05077.7 KPI37390.1 - 0.017 15.0 0.2 0.042 13.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Peptidase_M91 PF14891.1 KPI37390.1 - 0.063 13.3 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 Effector protein SprT-like PF10263.4 KPI37390.1 - 0.073 12.7 9.2 0.017 14.7 2.3 2.1 1 1 1 2 2 2 0 SprT-like family DUF3633 PF12315.3 KPI37390.1 - 0.08 12.2 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) HET PF06985.6 KPI37392.1 - 4.5e-31 107.8 0.0 6.9e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2781 PF10914.3 KPI37393.1 - 1.9e-26 92.6 12.4 2.2e-26 92.4 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Na_Ca_ex PF01699.19 KPI37393.1 - 0.13 11.8 2.9 0.2 11.2 2.0 1.3 1 0 0 1 1 1 0 Sodium/calcium exchanger protein EBP PF05241.7 KPI37393.1 - 0.13 11.2 6.0 0.096 11.6 3.4 1.4 1 1 0 1 1 1 0 Emopamil binding protein Kelch_4 PF13418.1 KPI37395.1 - 2e-16 59.4 6.4 7.8e-08 31.9 0.0 4.9 3 1 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KPI37395.1 - 4.7e-14 51.9 0.9 0.015 15.2 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 KPI37395.1 - 1.6e-13 50.1 3.8 6.2e-05 23.0 0.0 5.0 5 1 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 KPI37395.1 - 6e-13 48.5 20.0 1.7e-06 28.0 0.2 7.1 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.20 KPI37395.1 - 5.1e-06 25.9 7.9 0.0041 16.6 0.1 4.7 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 KPI37395.1 - 5.1e-05 22.8 8.7 0.026 14.3 0.0 5.2 5 1 0 5 5 5 2 Kelch motif MIT PF04212.13 KPI37396.1 - 5.2e-10 39.0 1.3 9.3e-10 38.2 0.9 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Cu-oxidase_3 PF07732.10 KPI37397.1 - 5.7e-34 116.3 3.9 2.2e-33 114.4 2.3 2.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KPI37397.1 - 1.2e-33 115.5 0.3 1.2e-33 115.5 0.2 2.9 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 KPI37397.1 - 1.3e-22 80.4 0.2 3.5e-22 78.9 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase ECM11 PF15463.1 KPI37399.1 - 1.2e-26 93.5 4.9 1.2e-26 93.5 3.4 2.2 2 0 0 2 2 2 1 Extracellular mutant protein 11 XPG_I_2 PF12813.2 KPI37400.1 - 2.7e-51 174.4 0.0 4.7e-51 173.6 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 KPI37400.1 - 0.0004 20.3 0.0 0.0017 18.3 0.0 2.0 2 0 0 2 2 2 1 XPG I-region PUF PF00806.14 KPI37401.1 - 1.5e-16 58.8 0.0 0.00029 20.1 0.0 7.2 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat Erg28 PF03694.8 KPI37402.1 - 8.8e-27 93.3 0.0 1.1e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Erg28 like protein Flavin_Reduct PF01613.13 KPI37403.1 - 1.5e-17 63.8 0.0 2.3e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Biotin_carb_C PF02785.14 KPI37404.1 - 0.11 12.4 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain LEA_4 PF02987.11 KPI37404.1 - 0.24 11.3 22.0 0.11 12.4 9.6 3.0 2 1 1 3 3 3 0 Late embryogenesis abundant protein DUF883 PF05957.8 KPI37404.1 - 0.7 10.3 5.8 0.49 10.8 0.9 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) CAP160 PF07918.6 KPI37404.1 - 0.88 9.2 0.1 0.88 9.2 0.1 2.5 3 0 0 3 3 3 0 CAP160 repeat CsbD PF05532.7 KPI37404.1 - 1.5 8.5 21.5 0.14 11.8 8.1 2.8 2 1 1 3 3 3 0 CsbD-like Myb_DNA-bind_6 PF13921.1 KPI37405.1 - 0.007 16.4 0.0 0.024 14.7 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain MFS_1 PF07690.11 KPI37406.1 - 2.3e-27 95.6 28.6 1.1e-26 93.3 20.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MIG-14_Wnt-bd PF06664.7 KPI37406.1 - 0.46 9.2 7.1 0.049 12.4 0.2 2.5 3 0 0 3 3 3 0 Wnt-binding factor required for Wnt secretion DUF3311 PF11755.3 KPI37406.1 - 1.1 8.9 0.0 1.1 8.9 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3311) DUF4231 PF14015.1 KPI37406.1 - 3.6 7.5 8.0 0.92 9.5 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Glyco_hydro_17 PF00332.13 KPI37407.1 - 0.0054 15.8 0.3 0.016 14.2 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 adh_short PF00106.20 KPI37408.1 - 1.3e-21 77.1 0.1 2.4e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI37408.1 - 6.3e-10 39.2 0.0 2e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI37408.1 - 0.00061 19.4 0.1 0.0026 17.4 0.0 2.0 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 KPI37408.1 - 0.0018 17.7 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KPI37408.1 - 0.0072 16.0 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KPI37408.1 - 0.014 13.8 0.1 0.019 13.4 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein Eno-Rase_NADH_b PF12242.3 KPI37408.1 - 0.035 13.8 0.9 0.3 10.8 0.5 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1428 PF07237.6 KPI37408.1 - 0.049 13.5 0.1 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) Spt5_N PF11942.3 KPI37410.1 - 1.4 9.6 20.4 0.036 14.6 3.7 3.5 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Metallophos PF00149.23 KPI37411.1 - 1e-07 31.5 1.7 4.1e-07 29.5 1.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KPI37411.1 - 1.1e-07 31.7 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GM_CSF PF01109.12 KPI37412.1 - 0.22 11.4 0.5 0.63 9.9 0.0 1.8 2 0 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor CAP_GLY PF01302.20 KPI37413.1 - 1.3e-15 56.8 0.8 2.3e-15 56.0 0.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF812 PF05667.6 KPI37413.1 - 0.00034 19.2 15.5 0.00034 19.2 10.8 3.5 2 1 1 4 4 4 1 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.7 KPI37413.1 - 0.007 16.1 9.1 0.007 16.1 6.3 3.8 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 KPI37413.1 - 0.34 8.7 24.3 0.13 10.0 12.8 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family PilJ PF13675.1 KPI37413.1 - 0.89 9.8 22.6 0.16 12.2 2.0 4.3 2 1 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term TBPIP PF07106.8 KPI37413.1 - 1.4 8.4 28.3 2.6 7.5 0.6 4.3 2 1 1 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BLOC1_2 PF10046.4 KPI37413.1 - 1.4 9.0 23.6 2.7 8.1 2.9 4.5 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.5 KPI37413.1 - 3.4 7.7 23.3 0.94 9.5 0.9 4.3 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 KPI37413.1 - 6.4 7.1 24.1 0.049 13.8 0.9 4.6 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Lge1 PF11488.3 KPI37413.1 - 7 6.9 20.4 0.69 10.1 0.7 4.6 4 0 0 4 4 4 0 Transcriptional regulatory protein LGE1 Fungal_trans_2 PF11951.3 KPI37414.1 - 1.8e-12 46.5 1.0 1.8e-12 46.5 0.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI37414.1 - 2.2e-08 33.8 11.5 3.9e-08 33.0 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEC-1_N PF04625.8 KPI37414.1 - 0.64 8.6 9.8 1.1 7.8 6.8 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Thaumatin PF00314.12 KPI37415.1 - 6.3e-35 120.5 0.5 8.4e-35 120.1 0.4 1.2 1 0 0 1 1 1 1 Thaumatin family DUF2945 PF11160.3 KPI37416.1 - 5.1e-13 48.6 3.8 6.9e-12 44.9 0.1 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF2945) CFIA_Pcf11 PF11526.3 KPI37416.1 - 6.4 6.9 11.8 15 5.7 0.0 3.2 2 1 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Amidase PF01425.16 KPI37417.1 - 1.1e-60 205.7 0.1 7.9e-60 202.9 0.1 1.9 1 1 0 1 1 1 1 Amidase Nucleoporin_C PF03177.9 KPI37419.1 - 6.1e-120 401.4 0.6 8.8e-120 400.9 0.4 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KPI37419.1 - 3.3e-79 266.6 0.2 4.3e-79 266.2 0.1 1.1 1 0 0 1 1 1 1 Nup133 N terminal like NHase_beta PF02211.10 KPI37420.1 - 0.026 14.2 0.3 0.031 13.9 0.2 1.0 1 0 0 1 1 1 0 Nitrile hydratase beta subunit APH PF01636.18 KPI37421.1 - 5.2e-31 108.1 0.0 7.9e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KPI37421.1 - 0.00022 20.4 0.0 0.00058 19.0 0.0 1.6 2 0 0 2 2 2 1 Ecdysteroid kinase RIO1 PF01163.17 KPI37421.1 - 0.02 14.2 0.0 0.068 12.5 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Epimerase PF01370.16 KPI37423.1 - 3.8e-09 36.3 0.0 3.7e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KPI37423.1 - 1.6e-06 28.3 0.0 4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KPI37423.1 - 0.0018 17.2 0.0 0.044 12.6 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 KPI37423.1 - 0.037 12.7 0.0 0.096 11.3 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1183 PF06682.7 KPI37425.1 - 0.016 14.7 2.7 0.021 14.4 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Secretin_N_2 PF07655.8 KPI37425.1 - 0.19 12.1 3.3 0.44 10.9 2.3 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain GalP_UDP_transf PF01087.17 KPI37426.1 - 4.5e-66 222.4 0.1 2.5e-64 216.7 0.0 2.3 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 KPI37426.1 - 4.9e-55 185.5 0.1 1.1e-54 184.4 0.0 1.6 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 KPI37426.1 - 0.00011 22.6 0.0 0.0013 19.2 0.0 2.3 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 KPI37426.1 - 0.016 15.4 0.0 0.086 13.0 0.0 2.2 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding Med13_N PF11597.3 KPI37426.1 - 0.073 11.7 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Sugar_tr PF00083.19 KPI37427.1 - 1.7e-131 438.9 23.9 1.9e-131 438.7 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI37427.1 - 8.6e-29 100.3 44.8 2.3e-23 82.4 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lig_chan PF00060.21 KPI37427.1 - 1.5 8.5 10.5 0.26 11.0 1.4 2.7 2 1 0 2 2 2 0 Ligand-gated ion channel AA_permease_2 PF13520.1 KPI37428.1 - 3.8e-35 121.2 34.5 3.8e-30 104.7 15.9 2.0 2 0 0 2 2 2 2 Amino acid permease MFS_1 PF07690.11 KPI37429.1 - 6.4e-30 104.0 35.9 1.7e-26 92.7 10.5 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MNHE PF01899.11 KPI37429.1 - 0.5 10.0 3.7 0.9 9.1 1.4 2.3 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit Spc97_Spc98 PF04130.8 KPI37430.1 - 1.6e-102 343.5 0.1 3.3e-102 342.5 0.1 1.5 2 0 0 2 2 2 1 Spc97 / Spc98 family 4HBT PF03061.17 KPI37431.1 - 9e-08 32.1 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KPI37431.1 - 4.9e-07 29.7 0.0 6.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT_2 PF13279.1 KPI37431.1 - 0.063 13.7 0.0 0.078 13.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily zf-CCCH PF00642.19 KPI37433.1 - 7.2e-09 35.1 16.6 3.4e-07 29.7 1.5 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KPI37433.1 - 1.4e-05 24.8 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KPI37433.1 - 0.00057 19.4 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI37433.1 - 0.052 13.5 0.0 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2213 PF09979.4 KPI37434.1 - 0.017 14.7 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) AA_permease PF00324.16 KPI37436.1 - 1.5e-69 234.5 39.6 2.2e-68 230.7 27.4 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI37436.1 - 2.1e-26 92.4 35.3 3.4e-26 91.7 24.4 1.3 1 1 0 1 1 1 1 Amino acid permease Peptidase_S9 PF00326.16 KPI37437.1 - 1.2e-39 135.7 0.3 1e-31 109.8 0.1 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KPI37437.1 - 3.1e-10 39.9 0.0 6.2e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI37437.1 - 2.1e-05 24.5 0.6 0.00013 21.8 0.4 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 KPI37437.1 - 0.0004 19.9 0.5 0.084 12.5 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat AXE1 PF05448.7 KPI37437.1 - 0.059 11.8 0.0 0.097 11.1 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PPR_2 PF13041.1 KPI37438.1 - 0.0068 16.3 0.0 0.091 12.7 0.0 2.4 2 0 0 2 2 2 1 PPR repeat family PWWP PF00855.12 KPI37439.1 - 1.5e-14 53.9 0.0 1.5e-14 53.9 0.0 2.7 2 1 1 3 3 3 1 PWWP domain DNA_mis_repair PF01119.14 KPI37439.1 - 0.035 13.5 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain KRE9 PF05390.6 KPI37440.1 - 1.7e-12 47.6 4.4 1.7e-12 47.6 3.1 2.2 2 1 1 3 3 3 1 Yeast cell wall synthesis protein KRE9/KNH1 PAP2_3 PF14378.1 KPI37441.1 - 3.8e-19 68.9 18.2 1.2e-10 41.1 0.3 3.8 4 1 0 4 4 4 3 PAP2 superfamily PAP2 PF01569.16 KPI37441.1 - 0.42 10.3 8.5 0.068 12.8 2.5 2.3 2 1 0 2 2 2 0 PAP2 superfamily Kinesin PF00225.18 KPI37443.1 - 1.2e-99 333.1 2.9 2.6e-99 332.1 2.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain FA_hydroxylase PF04116.8 KPI37444.1 - 1.2e-17 64.3 19.6 1.2e-17 64.3 13.6 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribonuc_L-PSP PF01042.16 KPI37445.1 - 6.5e-14 51.7 0.0 8.7e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Pyridoxal_deC PF00282.14 KPI37446.1 - 7.7e-67 225.3 0.0 6.7e-65 218.9 0.0 2.2 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KPI37446.1 - 7.2e-06 25.3 0.0 9.8e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KPI37446.1 - 0.00019 20.3 0.0 0.00034 19.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V VirionAssem_T7 PF11653.3 KPI37446.1 - 0.11 13.3 2.0 33 5.3 0.3 3.3 3 0 0 3 3 3 0 Bacteriophage T7 virion assembly protein INCENP_N PF12178.3 KPI37446.1 - 0.16 11.4 0.1 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal FA_desaturase PF00487.19 KPI37447.1 - 7.4 5.9 9.2 40 3.5 6.3 2.1 1 1 0 1 1 1 0 Fatty acid desaturase Arf PF00025.16 KPI37448.1 - 1.2e-58 197.1 0.4 1.4e-46 157.9 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 KPI37448.1 - 8.9e-10 37.8 0.7 1.8e-06 26.9 0.1 2.3 1 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KPI37448.1 - 2.2e-08 33.5 0.0 6.3e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KPI37448.1 - 2.5e-07 30.2 0.0 7.4e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KPI37448.1 - 3.6e-07 30.6 0.0 6.4e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KPI37448.1 - 8.2e-07 28.9 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KPI37448.1 - 1.4e-05 24.4 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KPI37448.1 - 0.00038 19.9 0.0 0.16 11.4 0.0 2.0 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 KPI37448.1 - 0.049 13.0 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KPI37448.1 - 0.11 11.8 0.0 3.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.1 KPI37448.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 KPI37448.1 - 0.14 11.5 0.2 6.3 6.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CBFD_NFYB_HMF PF00808.18 KPI37449.1 - 5.8e-14 51.9 0.8 8.9e-14 51.3 0.6 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KPI37449.1 - 3e-06 27.2 0.4 4.8e-06 26.5 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIIA PF03153.8 KPI37449.1 - 0.62 9.9 9.5 0.83 9.4 6.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAP_central PF04928.12 KPI37450.1 - 4e-100 333.8 0.0 5e-100 333.5 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KPI37450.1 - 8.3e-38 129.3 0.0 2.2e-37 128.0 0.0 1.7 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KPI37450.1 - 2.5e-08 34.1 0.1 6e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 KPI37450.1 - 0.14 9.6 0.0 0.21 9.0 0.0 1.1 1 0 0 1 1 1 0 Nrap protein Lactonase PF10282.4 KPI37451.1 - 0.0048 16.0 0.2 0.0073 15.4 0.1 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller ECH PF00378.15 KPI37452.1 - 4.8e-46 156.8 0.0 6e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF3482 PF11981.3 KPI37453.1 - 0.065 12.4 13.1 0.89 8.7 9.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3482) Gly-zipper_Omp PF13488.1 KPI37453.1 - 0.12 12.0 28.3 0.62 9.7 14.4 2.6 2 0 0 2 2 2 0 Glycine zipper TraT PF05818.7 KPI37453.1 - 7.3 5.9 11.4 0.26 10.6 3.7 1.8 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Mob1_phocein PF03637.12 KPI37454.1 - 1e-22 80.6 0.0 1.7e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family Peptidase_M28 PF04389.12 KPI37456.1 - 8.7e-26 90.7 0.0 1.7e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KPI37456.1 - 2.4e-06 27.1 0.0 4.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 AA_permease PF00324.16 KPI37457.1 - 4.4e-98 328.6 43.0 5e-98 328.5 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI37457.1 - 8e-29 100.4 46.6 1e-28 100.0 32.3 1.1 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_3 PF07859.8 KPI37458.1 - 6.8e-20 71.5 0.0 8.8e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KPI37458.1 - 1.2e-12 47.1 0.0 2.7e-12 46.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) p450 PF00067.17 KPI37459.1 - 7e-27 94.0 0.8 3.2e-22 78.7 0.1 2.9 2 2 0 2 2 2 2 Cytochrome P450 Alpha-amylase PF00128.19 KPI37460.1 - 5.3e-38 131.1 0.0 8.1e-37 127.2 0.0 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KPI37460.1 - 0.01 14.7 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme DUF3459 PF11941.3 KPI37460.1 - 0.032 14.3 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) YqeY PF09424.5 KPI37461.1 - 2.6e-14 53.3 3.4 3.4e-14 52.9 2.4 1.2 1 0 0 1 1 1 1 Yqey-like protein HrpJ PF07201.6 KPI37461.1 - 0.082 12.9 2.1 0.2 11.6 1.5 1.5 1 1 1 2 2 2 0 HrpJ-like domain FAD_binding_3 PF01494.14 KPI37462.1 - 1.2e-14 54.1 0.6 3.4e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KPI37462.1 - 7.5e-08 31.6 2.1 1.8e-07 30.4 1.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI37462.1 - 4.8e-07 29.6 1.1 1.2e-06 28.4 0.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI37462.1 - 5.3e-07 29.7 0.1 1.4e-06 28.3 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI37462.1 - 5.1e-06 26.7 1.4 1.5e-05 25.3 0.5 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI37462.1 - 0.00013 20.9 1.3 0.0002 20.3 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KPI37462.1 - 0.0027 17.8 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI37462.1 - 0.0039 15.7 1.0 0.0061 15.0 0.7 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KPI37462.1 - 0.0053 15.6 0.6 0.01 14.7 0.4 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 KPI37462.1 - 0.0075 16.0 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 KPI37462.1 - 0.013 14.4 0.5 0.028 13.3 0.3 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.2 KPI37462.1 - 0.013 14.5 2.0 0.024 13.7 1.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KPI37462.1 - 0.026 14.1 0.2 0.026 14.1 0.2 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KPI37462.1 - 0.046 13.5 0.6 0.25 11.1 0.3 2.1 1 1 1 2 2 2 0 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KPI37462.1 - 0.047 12.7 0.1 0.16 10.9 0.1 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_2 PF03446.10 KPI37462.1 - 0.068 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Trp_halogenase PF04820.9 KPI37462.1 - 0.17 10.4 1.4 1.7 7.2 0.5 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Sugar_tr PF00083.19 KPI37463.1 - 1.8e-97 326.7 30.5 1.1e-56 192.3 2.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI37463.1 - 2.5e-23 82.3 36.4 4.3e-15 55.2 8.6 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Phage_holin_2 PF04550.7 KPI37463.1 - 0.1 12.7 0.9 0.81 9.8 0.5 2.4 2 0 0 2 2 2 0 Phage holin family 2 CAMSAP_CH PF11971.3 KPI37463.1 - 0.22 11.1 1.8 6.6 6.4 0.1 2.3 1 1 1 2 2 2 0 CAMSAP CH domain DUF3924 PF13062.1 KPI37463.1 - 8.3 6.3 5.8 16 5.4 1.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3924) FAD_binding_4 PF01565.18 KPI37464.1 - 6.7e-16 58.0 0.0 1.1e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Peptidase_M1 PF01433.15 KPI37465.1 - 8.2e-132 439.9 0.2 1.5e-131 439.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KPI37465.1 - 7e-74 248.9 0.7 1.1e-73 248.3 0.5 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KPI37465.1 - 3e-20 72.5 1.7 8.1e-20 71.1 1.2 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2808 PF10989.3 KPI37465.1 - 0.0013 18.3 0.0 0.0032 17.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) ATP12 PF07542.6 KPI37466.1 - 5e-34 116.8 0.0 2e-33 114.9 0.0 2.1 2 0 0 2 2 2 1 ATP12 chaperone protein Pyr_redox_3 PF13738.1 KPI37466.1 - 4.4e-20 72.6 0.0 1.3e-19 71.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI37466.1 - 3.6e-14 51.8 0.0 3.1e-12 45.4 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KPI37466.1 - 1.2e-10 41.6 0.6 0.00011 22.1 0.0 3.5 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI37466.1 - 6.6e-10 38.4 0.2 1.1e-06 27.7 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KPI37466.1 - 1.5e-09 38.1 0.9 0.013 15.8 0.0 4.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI37466.1 - 1.7e-09 37.0 0.9 0.0021 17.0 0.0 4.3 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI37466.1 - 3.2e-08 33.4 0.4 3.3e-06 27.0 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KPI37466.1 - 1.5e-07 30.2 0.9 0.001 17.6 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.1 KPI37466.1 - 2.7e-07 30.4 2.6 0.00037 20.3 0.3 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KPI37466.1 - 4e-06 25.9 3.3 0.01 14.7 0.0 4.0 5 0 0 5 5 5 2 FAD binding domain TrkA_N PF02254.13 KPI37466.1 - 3.4e-05 23.8 0.1 0.092 12.7 0.0 3.0 2 0 0 2 2 2 2 TrkA-N domain Thi4 PF01946.12 KPI37466.1 - 4.2e-05 22.7 0.1 0.001 18.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.15 KPI37466.1 - 4.6e-05 23.5 0.2 0.0055 16.8 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KPI37466.1 - 0.00032 19.8 1.2 0.0077 15.3 0.1 2.8 2 1 1 3 3 3 1 FAD binding domain GIDA PF01134.17 KPI37466.1 - 0.0013 17.6 1.3 0.9 8.3 0.1 3.2 3 1 0 3 3 3 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 KPI37466.1 - 0.0031 16.6 0.0 1.6 7.6 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase 2-Hacid_dh_C PF02826.14 KPI37466.1 - 0.0073 15.4 0.0 1.4 8.0 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 KPI37466.1 - 0.023 13.3 0.7 1.3 7.5 0.1 2.4 2 0 0 2 2 2 0 Tryptophan halogenase F420_oxidored PF03807.12 KPI37466.1 - 0.026 14.9 0.3 1.8 9.0 0.0 3.1 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 KPI37466.1 - 0.03 14.5 0.0 1.3 9.3 0.0 3.0 3 0 0 3 3 2 0 Putative NAD(P)-binding FHA PF00498.21 KPI37467.1 - 1.5e-13 50.6 0.0 2.9e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Methyltransf_23 PF13489.1 KPI37468.1 - 2.2e-10 40.5 0.1 6.4e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI37468.1 - 3.1e-05 24.3 0.0 0.00013 22.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI37468.1 - 3.2e-05 24.4 0.0 0.00018 22.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI37468.1 - 0.0002 21.7 0.0 0.00055 20.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 KPI37468.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase zf-AN1 PF01428.11 KPI37469.1 - 7.5e-24 83.3 23.2 2e-12 46.7 6.5 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 KPI37469.1 - 0.00065 19.5 14.6 0.023 14.5 2.3 2.4 2 0 0 2 2 2 2 IBR domain Transp_Tc5_C PF04236.10 KPI37469.1 - 0.024 14.8 17.8 0.086 13.0 2.9 2.5 2 1 0 2 2 2 0 Tc5 transposase C-terminal domain C1_4 PF07975.7 KPI37469.1 - 3.8 7.5 22.3 6.2 6.9 2.9 2.9 2 1 0 2 2 2 0 TFIIH C1-like domain REGB_T4 PF10715.4 KPI37471.1 - 0.016 15.3 1.5 0.041 14.0 0.1 2.2 2 0 0 2 2 2 0 Endoribonuclease RegB T4-bacteriophage encoded Pyr_redox_2 PF07992.9 KPI37472.1 - 6.8e-14 52.2 0.0 1.1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI37472.1 - 8.6e-07 28.1 0.0 0.0016 17.3 0.1 2.3 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.19 KPI37472.1 - 0.00032 19.6 0.1 0.012 14.5 0.0 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 KPI37472.1 - 0.00064 18.6 0.0 0.16 10.8 0.1 3.1 2 1 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KPI37472.1 - 0.0031 16.6 0.8 0.0041 16.2 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KPI37472.1 - 0.0033 15.9 0.0 0.058 11.8 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KPI37472.1 - 0.013 15.6 0.2 5.2 7.0 0.0 2.3 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI37472.1 - 0.02 13.9 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 KPI37472.1 - 0.024 13.7 0.5 0.13 11.3 0.2 2.0 1 1 1 2 2 2 0 FAD dependent oxidoreductase K_oxygenase PF13434.1 KPI37472.1 - 0.046 12.6 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KPI37472.1 - 0.12 12.4 0.3 0.4 10.7 0.2 2.0 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KPI37472.1 - 0.16 10.5 0.1 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Alpha-amylase PF00128.19 KPI37474.1 - 6.9e-27 94.6 0.0 1.1e-26 93.9 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 KPI37474.1 - 0.00018 19.4 0.0 0.032 12.0 0.0 2.5 2 1 1 3 3 3 2 Glycosyl hydrolase family 70 DUF1939 PF09154.5 KPI37474.1 - 0.0044 16.9 0.1 0.0098 15.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Alpha-amylase_C PF02806.13 KPI37474.1 - 0.018 15.1 0.1 0.23 11.6 0.0 2.3 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain Thymidylat_synt PF00303.14 KPI37475.1 - 5.2e-111 369.9 0.0 6.2e-111 369.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Fungal_trans_2 PF11951.3 KPI37477.1 - 4.6e-05 22.1 0.0 7.1e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box-like PF12937.2 KPI37478.1 - 0.00011 21.8 0.2 0.00026 20.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KPI37478.1 - 0.00012 21.6 0.1 0.00024 20.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain Rota_NS35 PF02509.9 KPI37478.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 DUF4408 PF14364.1 KPI37478.1 - 0.17 11.5 0.1 0.32 10.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4408) Abhydrolase_6 PF12697.2 KPI37479.1 - 7.6e-27 94.6 0.0 9.5e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI37479.1 - 3.9e-10 39.6 0.0 1.9e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI37479.1 - 1e-07 31.8 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 KPI37479.1 - 0.0043 15.8 0.2 0.022 13.5 0.0 2.1 2 1 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 KPI37479.1 - 0.021 14.6 0.0 0.064 13.1 0.0 1.9 1 0 0 1 1 1 0 Putative lysophospholipase Ndr PF03096.9 KPI37479.1 - 0.13 10.6 0.0 1.5 7.2 0.0 2.0 2 0 0 2 2 2 0 Ndr family adh_short_C2 PF13561.1 KPI37480.1 - 3.7e-24 85.8 0.4 4.4e-24 85.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI37480.1 - 1.9e-23 83.1 2.6 2.7e-23 82.7 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI37480.1 - 9.1e-10 38.4 0.9 1.3e-09 38.0 0.7 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KPI37480.1 - 0.013 14.3 0.1 0.019 13.8 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KPI37480.1 - 0.026 13.2 0.7 0.055 12.1 0.5 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_trans_4_4 PF13579.1 KPI37480.1 - 0.15 12.2 0.8 0.22 11.6 0.4 1.6 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Polysacc_deac_1 PF01522.16 KPI37481.1 - 9.7e-20 70.4 0.0 1.3e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Ras PF00071.17 KPI37483.1 - 1.6e-60 203.1 0.3 2.6e-60 202.5 0.2 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KPI37483.1 - 2.3e-17 63.5 0.0 5.5e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KPI37483.1 - 1.7e-13 50.1 0.1 2.9e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KPI37483.1 - 0.00021 20.7 0.2 0.00048 19.6 0.1 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF1691 PF07950.6 KPI37484.1 - 1.6e-37 127.7 4.5 1.1e-20 73.5 1.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Herpes_US9 PF06072.6 KPI37484.1 - 0.14 12.0 0.2 0.38 10.6 0.1 1.7 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 IncA PF04156.9 KPI37486.1 - 0.0073 15.9 1.3 0.011 15.3 0.9 1.2 1 0 0 1 1 1 1 IncA protein DUF2937 PF11157.3 KPI37486.1 - 0.032 13.5 0.7 0.06 12.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) MFS_1 PF07690.11 KPI37488.1 - 1e-10 40.8 15.8 1e-10 40.8 10.9 2.9 2 2 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI37488.1 - 4.6e-06 25.4 6.1 4.6e-06 25.4 4.2 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter F-box-like PF12937.2 KPI37489.1 - 2e-05 24.2 0.4 3.9e-05 23.2 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KPI37489.1 - 0.0023 17.5 2.0 0.0042 16.7 1.4 1.4 1 0 0 1 1 1 1 F-box domain Aldo_ket_red PF00248.16 KPI37490.1 - 2.8e-65 219.9 0.0 3.2e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4179 PF13786.1 KPI37491.1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) GST_N_2 PF13409.1 KPI37494.1 - 4e-06 26.7 0.0 7.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KPI37494.1 - 9.2e-06 25.7 0.0 2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KPI37494.1 - 7.8e-05 22.5 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI37494.1 - 0.00013 21.8 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KPI37494.1 - 0.021 14.9 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KPI37494.1 - 0.076 13.4 0.0 0.26 11.8 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DIOX_N PF14226.1 KPI37496.1 - 1.5e-17 64.1 0.0 1.2e-16 61.2 0.0 2.4 2 1 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI37496.1 - 1.2e-07 31.9 0.0 2.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EthD PF07110.6 KPI37497.1 - 0.0091 16.9 0.0 0.013 16.4 0.0 1.3 1 0 0 1 1 1 1 EthD domain TMEM247 PF15444.1 KPI37498.1 - 0.12 12.2 0.6 0.24 11.2 0.4 1.7 1 0 0 1 1 1 0 Transmembrane protein 247 WTF PF03303.8 KPI37498.1 - 0.2 11.0 0.7 0.32 10.3 0.5 1.3 1 0 0 1 1 1 0 WTF protein PAP2 PF01569.16 KPI37499.1 - 3.6e-22 78.4 2.0 3.6e-22 78.4 1.4 2.0 2 0 0 2 2 2 1 PAP2 superfamily FUSC_2 PF13515.1 KPI37499.1 - 0.55 10.1 7.5 1.2 9.0 0.1 2.8 2 1 1 3 3 3 0 Fusaric acid resistance protein-like CoA_transf_3 PF02515.12 KPI37500.1 - 5.4e-38 130.1 1.0 1.6e-36 125.3 0.0 2.3 2 1 0 2 2 2 2 CoA-transferase family III DUF4420 PF14390.1 KPI37500.1 - 0.054 12.3 0.0 0.085 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4420) PAP2 PF01569.16 KPI37501.1 - 6.2e-09 35.6 11.8 6.2e-09 35.6 8.2 2.5 2 1 1 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.1 KPI37501.1 - 0.00063 19.3 7.2 0.0022 17.5 5.0 1.9 1 1 0 1 1 1 1 PAP2 superfamily SieB PF14163.1 KPI37501.1 - 0.069 12.7 0.3 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 Superinfection exclusion protein B CbtB PF09489.5 KPI37501.1 - 0.083 12.8 3.1 0.095 12.6 0.1 2.6 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) Arrestin_N PF00339.24 KPI37502.1 - 6.2e-14 52.0 0.0 1e-08 35.1 0.0 2.6 1 1 1 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 KPI37502.1 - 0.0058 15.8 0.0 0.033 13.3 0.0 2.0 2 0 0 2 2 2 1 Bul1 C terminus p450 PF00067.17 KPI37503.1 - 2.2e-53 181.4 0.0 2.8e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NCA2 PF08637.5 KPI37504.1 - 6.6e-88 294.3 0.1 1.5e-87 293.2 0.0 1.6 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 p450 PF00067.17 KPI37505.1 - 7.1e-54 183.0 0.0 8.4e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 KPI37506.1 - 2.4e-13 49.3 8.3 0.00013 21.7 0.1 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 KPI37506.1 - 1.4e-06 28.1 0.1 0.022 14.4 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KPI37506.1 - 9.4e-05 20.8 0.0 0.00017 20.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome D1 heme domain BTB PF00651.26 KPI37507.1 - 9.4e-05 22.3 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Zn_clus PF00172.13 KPI37508.1 - 2.7e-06 27.2 8.4 4.5e-06 26.4 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.4 KPI37508.1 - 0.044 13.7 3.2 0.077 13.0 2.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) SpoIIIAH PF12685.2 KPI37509.1 - 4.7 6.6 6.1 1.3 8.4 0.3 2.0 1 1 1 2 2 2 0 SpoIIIAH-like protein SHS2_Rpb7-N PF03876.12 KPI37510.1 - 0.0034 17.4 0.0 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 eIF3g PF12353.3 KPI37510.1 - 8 6.3 14.1 4.1 7.3 6.7 2.4 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Na_Ca_ex PF01699.19 KPI37511.1 - 7.7e-39 132.4 40.6 4.4e-22 78.1 10.3 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Glyco_hydro_31 PF01055.21 KPI37512.1 - 0.086 11.6 0.1 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 FMN_red PF03358.10 KPI37513.1 - 6.1e-22 77.7 0.0 8.7e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Epimerase PF01370.16 KPI37514.1 - 1.5e-21 76.9 0.0 1.9e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI37514.1 - 2.2e-12 46.2 0.0 2.8e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KPI37514.1 - 7.6e-10 38.1 0.0 4.8e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KPI37514.1 - 8.5e-08 31.4 0.0 1.4e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KPI37514.1 - 2.5e-05 24.3 0.0 3.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Ldh_1_N PF00056.18 KPI37514.1 - 0.0013 18.5 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.20 KPI37514.1 - 0.0013 18.6 0.1 0.014 15.3 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Pyr_redox_2 PF07992.9 KPI37516.1 - 1.8e-31 109.6 0.0 5.9e-31 107.9 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KPI37516.1 - 7.1e-15 54.3 0.3 3e-14 52.3 0.0 2.1 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 KPI37516.1 - 1e-13 51.4 0.4 3.8e-12 46.4 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI37516.1 - 8.6e-12 45.5 0.0 4.5e-06 26.8 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 KPI37516.1 - 1e-06 28.4 0.0 2.6e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.1 KPI37516.1 - 3.8e-06 27.1 0.0 1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal DAO PF01266.19 KPI37516.1 - 2.6e-05 23.2 0.4 0.12 11.2 0.0 3.3 2 1 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KPI37516.1 - 6.9e-05 21.9 0.0 0.23 10.3 0.0 2.3 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 KPI37516.1 - 0.022 15.0 0.1 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 KPI37516.1 - 0.034 12.6 0.0 4.4 5.6 0.0 2.4 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.13 KPI37516.1 - 0.18 11.8 0.7 1.4 8.9 0.0 2.6 3 0 0 3 3 3 0 TrkA-N domain AMP-binding PF00501.23 KPI37517.1 - 1.9e-73 247.2 0.0 2.4e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI37517.1 - 1.6e-15 57.8 1.2 3.9e-15 56.5 0.8 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.13 KPI37518.1 - 1.4e-08 34.5 9.1 2.1e-08 33.9 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KPI37518.1 - 0.0019 17.0 0.0 0.015 14.1 0.0 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.27 KPI37519.1 - 5.4e-24 83.1 14.0 1.6e-06 27.7 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KPI37519.1 - 0.00062 19.5 0.3 0.064 12.9 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 KPI37519.1 - 0.09 12.2 0.0 0.95 9.0 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_16 PF00722.16 KPI37520.1 - 1.9e-43 147.9 3.9 3.4e-43 147.1 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 KPI37520.1 - 0.06 13.3 13.2 0.13 12.2 9.2 1.5 1 0 0 1 1 1 0 Chitin recognition protein tRNA-synt_2d PF01409.15 KPI37523.1 - 4.3e-88 294.6 0.0 5.5e-88 294.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 KPI37523.1 - 8.7e-06 24.7 0.2 0.00026 19.8 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KPI37523.1 - 6.5e-05 22.5 0.1 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) CLTH PF10607.4 KPI37524.1 - 6e-31 107.0 0.1 1.2e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 KPI37524.1 - 2.8e-21 75.8 0.1 4.5e-21 75.2 0.1 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 KPI37524.1 - 0.008 15.9 1.2 0.071 12.9 0.1 2.8 3 0 0 3 3 3 1 LisH InvH PF04741.7 KPI37524.1 - 0.022 14.6 0.6 0.078 12.8 0.1 2.1 2 0 0 2 2 2 0 InvH outer membrane lipoprotein Profilin PF00235.14 KPI37525.1 - 1.9e-44 150.6 0.5 2.2e-44 150.4 0.4 1.0 1 0 0 1 1 1 1 Profilin CHASE4 PF05228.8 KPI37525.1 - 0.066 12.7 0.0 0.093 12.3 0.0 1.4 1 1 0 1 1 1 0 CHASE4 domain Fork_head PF00250.13 KPI37526.1 - 1e-12 47.9 0.0 2.2e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Fork head domain RNA_pol_Rpb1_1 PF04997.7 KPI37528.1 - 9.1e-73 245.4 0.0 1.1e-72 245.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 Elf1 PF05129.8 KPI37528.1 - 0.66 9.7 3.2 3.4 7.4 2.2 2.1 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Amidase PF01425.16 KPI37529.1 - 2.7e-64 217.6 0.0 3.2e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Amidase FAD_binding_3 PF01494.14 KPI37530.1 - 8e-22 77.7 0.1 1e-21 77.3 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI37530.1 - 6.2e-06 25.3 6.7 0.0018 17.2 2.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 KPI37530.1 - 1e-05 24.7 0.5 1.6e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KPI37530.1 - 1.1e-05 25.3 1.2 2.1e-05 24.4 0.9 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KPI37530.1 - 9e-05 21.4 0.0 0.00043 19.2 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.9 KPI37530.1 - 0.00024 21.0 0.8 0.00071 19.5 0.5 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI37530.1 - 0.00046 19.9 1.0 0.0021 17.8 0.7 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KPI37530.1 - 0.001 19.4 1.0 0.004 17.5 0.4 2.3 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI37530.1 - 0.001 18.0 2.8 0.0023 16.8 1.8 1.6 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 KPI37530.1 - 0.0013 17.7 0.9 0.0039 16.1 0.4 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 KPI37530.1 - 0.0029 16.1 0.9 0.0043 15.5 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KPI37530.1 - 0.012 15.6 0.4 0.048 13.7 0.3 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KPI37530.1 - 0.014 14.5 1.3 0.022 13.8 0.9 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KPI37530.1 - 0.019 13.6 0.7 0.17 10.4 0.4 2.2 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.16 KPI37530.1 - 0.019 14.5 0.7 0.84 9.1 0.4 2.5 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 KPI37530.1 - 0.13 11.9 0.4 0.3 10.8 0.2 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HDPD PF02924.9 KPI37530.1 - 0.22 11.3 5.8 6.6 6.5 4.0 2.2 1 1 0 1 1 1 0 Bacteriophage lambda head decoration protein D DUF3425 PF11905.3 KPI37531.1 - 9.1e-20 70.9 0.7 2.1e-19 69.7 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF4646 PF15496.1 KPI37532.1 - 0.00083 19.4 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) F_bP_aldolase PF01116.15 KPI37533.1 - 1.3e-83 280.4 0.1 1.5e-83 280.2 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF72 PF01904.13 KPI37533.1 - 0.09 12.5 0.0 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF72 COesterase PF00135.23 KPI37534.1 - 5.7e-65 220.0 0.0 7e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI37534.1 - 8e-08 32.1 0.6 4.4e-05 23.1 0.4 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.17 KPI37536.1 - 2.1e-43 148.5 0.0 3e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.2 KPI37537.1 - 7.3e-29 99.9 0.1 6.5e-09 36.0 0.0 4.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KPI37537.1 - 1.2e-27 94.2 9.5 7.1e-07 28.7 0.0 7.6 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.1 KPI37537.1 - 1.3e-17 63.3 5.1 1.2e-05 25.3 0.0 5.9 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KPI37537.1 - 1.4e-17 63.6 0.6 0.00013 22.3 0.0 5.6 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI37537.1 - 3e-17 60.9 0.5 0.0017 18.4 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat HflK_N PF12221.3 KPI37537.1 - 0.039 13.7 0.5 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial membrane protein N terminal DUF3361 PF11841.3 KPI37538.1 - 0.11 12.2 0.2 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) AA_kinase PF00696.23 KPI37539.1 - 1.3e-33 116.5 0.4 1.3e-33 116.5 0.3 1.6 2 0 0 2 2 2 1 Amino acid kinase family adh_short PF00106.20 KPI37539.1 - 1e-25 90.5 1.1 1.3e-24 87.0 0.1 3.1 4 0 0 4 4 4 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI37539.1 - 2.5e-15 56.9 0.1 6.4e-15 55.5 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PUA PF01472.15 KPI37539.1 - 2e-13 49.8 1.9 2.3e-12 46.4 0.3 2.9 2 1 0 2 2 2 1 PUA domain KR PF08659.5 KPI37539.1 - 2.5e-10 40.3 0.6 6.2e-10 39.0 0.1 2.0 2 0 0 2 2 2 1 KR domain DUF4396 PF14342.1 KPI37540.1 - 2.9e-33 114.9 11.6 2.9e-33 114.9 8.0 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4396) Zip PF02535.17 KPI37540.1 - 0.0042 16.1 0.0 0.0074 15.3 0.0 1.5 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2946 PF11162.3 KPI37540.1 - 0.016 15.3 4.4 0.03 14.5 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) SelP_N PF04592.9 KPI37540.1 - 4.1 6.7 9.2 5.9 6.2 6.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FAD_binding_3 PF01494.14 KPI37541.1 - 7.2e-29 100.9 3.1 2.6e-25 89.2 0.0 2.7 1 1 1 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KPI37541.1 - 0.15 10.9 0.1 2.5 6.9 0.1 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein Oxidored_molyb PF00174.14 KPI37542.1 - 5.8e-56 188.5 0.0 8.8e-56 187.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KPI37542.1 - 3e-30 104.5 0.0 5.3e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 KPI37542.1 - 5.6e-13 48.4 0.5 1.7e-12 46.9 0.1 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain BNR_2 PF13088.1 KPI37542.1 - 0.0031 16.8 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 BNR repeat-like domain FAD-oxidase_C PF02913.14 KPI37543.1 - 6.3e-53 179.6 0.8 8.8e-53 179.1 0.5 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KPI37543.1 - 2.5e-35 120.9 0.0 2.5e-35 120.9 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Mito_fiss_reg PF05308.6 KPI37543.1 - 0.43 9.8 3.1 0.81 9.0 2.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator p450 PF00067.17 KPI37548.1 - 3.4e-53 180.8 0.0 5.8e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_3 PF13738.1 KPI37548.1 - 3.9e-30 105.4 0.5 8.2e-30 104.3 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI37548.1 - 5e-12 46.1 0.0 3.6e-07 30.2 0.0 2.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI37548.1 - 6.8e-12 44.9 2.2 1.1e-08 34.4 0.1 3.2 2 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KPI37548.1 - 3.2e-11 43.4 0.4 0.017 15.5 0.0 3.5 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI37548.1 - 3.2e-10 38.8 0.1 9.6e-08 30.6 0.0 2.6 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI37548.1 - 1.3e-07 31.5 0.1 1.1e-05 25.2 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KPI37548.1 - 2e-07 30.9 3.2 0.013 15.3 0.0 3.6 4 0 0 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.19 KPI37548.1 - 2.7e-06 26.5 9.1 0.01 14.7 0.4 3.9 3 1 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KPI37548.1 - 4e-05 22.2 1.7 0.11 10.9 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein IlvN PF07991.7 KPI37548.1 - 4.2e-05 22.9 0.1 0.044 13.1 0.0 2.6 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 KPI37548.1 - 4.6e-05 22.6 0.3 0.0064 15.6 0.0 2.8 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 KPI37548.1 - 9.8e-05 21.5 0.0 0.023 13.7 0.0 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Shikimate_DH PF01488.15 KPI37548.1 - 0.00011 22.2 0.0 0.37 10.8 0.0 2.7 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KPI37548.1 - 0.00056 19.6 0.2 0.038 13.6 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KPI37548.1 - 0.00065 18.7 0.9 0.34 9.7 0.2 3.6 3 1 0 3 3 3 1 Lycopene cyclase protein NAD_binding_10 PF13460.1 KPI37548.1 - 0.0011 19.0 0.1 0.61 10.0 0.0 2.5 2 0 0 2 2 2 1 NADH(P)-binding FAD_binding_3 PF01494.14 KPI37548.1 - 0.0014 17.7 0.1 0.0048 16.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KPI37548.1 - 0.0072 15.4 0.1 0.57 9.2 0.0 3.1 3 0 0 3 3 3 1 Thi4 family NAD_binding_7 PF13241.1 KPI37548.1 - 0.013 15.7 0.0 0.25 11.6 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.12 KPI37548.1 - 0.059 13.8 0.1 2 8.8 0.0 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KPI37548.1 - 0.1 12.6 0.1 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.19 KPI37548.1 - 0.13 11.0 2.2 0.49 9.1 0.1 2.6 3 0 0 3 3 3 0 FAD binding domain AlaDh_PNT_C PF01262.16 KPI37548.1 - 0.17 11.4 0.1 0.51 9.8 0.0 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 KPI37548.1 - 0.58 9.8 3.1 3.4 7.3 0.0 2.7 3 0 0 3 3 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF2839 PF10999.3 KPI37549.1 - 0.36 10.9 2.4 0.37 10.8 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2839) CAP PF00188.21 KPI37550.1 - 6.8e-05 23.3 0.2 0.00012 22.6 0.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Sulfate_transp PF00916.15 KPI37551.1 - 2.8e-58 197.1 6.2 2.8e-58 197.1 4.3 1.7 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KPI37551.1 - 5e-28 96.6 7.0 7.8e-28 95.9 2.2 2.8 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KPI37551.1 - 4.3e-13 48.7 0.0 9.2e-13 47.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain MotB_plug PF13677.1 KPI37551.1 - 0.00019 20.6 0.5 0.0006 19.0 0.3 1.8 1 0 0 1 1 1 1 Membrane MotB of proton-channel complex MotA/MotB CCDC92 PF14916.1 KPI37552.1 - 0.019 14.5 4.3 0.019 14.5 3.0 1.7 2 0 0 2 2 2 0 Coiled-coil domain of unknown function APG6 PF04111.7 KPI37552.1 - 0.13 11.3 2.2 0.18 10.8 1.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FUSC PF04632.7 KPI37552.1 - 0.33 9.3 5.5 0.4 9.0 3.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SNF2_N PF00176.18 KPI37553.1 - 3.5e-52 177.0 0.5 5.2e-52 176.5 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 KPI37553.1 - 3.4e-17 62.1 0.1 1.2e-16 60.3 0.1 2.1 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 KPI37553.1 - 6.1e-12 45.2 0.0 3.7e-11 42.7 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 KPI37553.1 - 8.6e-05 22.0 0.0 0.00019 20.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KPI37553.1 - 0.00021 21.2 0.3 0.002 17.9 0.0 2.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KPI37553.1 - 0.0036 16.1 0.0 0.0095 14.7 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF1774 PF08611.5 KPI37554.1 - 1.1e-22 79.9 11.6 1.1e-22 79.9 8.0 2.2 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) DnaJ PF00226.26 KPI37555.1 - 6.5e-13 48.2 0.0 1.4e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Zn_clus PF00172.13 KPI37555.1 - 1.2e-09 37.9 7.7 2e-09 37.1 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1720 PF08226.6 KPI37556.1 - 0.04 13.9 1.4 0.18 11.9 0.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) WD40 PF00400.27 KPI37557.1 - 1.4e-23 81.8 2.5 1.2e-05 25.0 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 KPI37557.1 - 0.015 15.0 0.2 23 4.6 0.0 3.4 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A RINT1_TIP1 PF04437.8 KPI37559.1 - 1.8e-122 409.4 0.2 2.2e-121 405.8 0.0 2.1 2 0 0 2 2 2 1 RINT-1 / TIP-1 family DIL PF01843.14 KPI37559.1 - 0.014 15.2 0.7 0.047 13.5 0.0 2.3 2 0 0 2 2 2 0 DIL domain Dzip-like_N PF13815.1 KPI37559.1 - 1 9.1 10.7 0.52 10.1 0.2 2.6 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Lipase_3 PF01764.20 KPI37560.1 - 4.6e-06 26.2 0.0 9.8e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KPI37560.1 - 0.002 17.9 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KPI37560.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 KPI37560.1 - 0.023 14.5 0.3 0.067 13.0 0.2 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family 6PGD PF00393.14 KPI37561.1 - 2e-65 220.8 0.0 9e-65 218.7 0.0 1.8 1 1 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KPI37561.1 - 9.2e-27 93.8 0.0 1.8e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KPI37561.1 - 0.035 13.7 0.0 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_11 PF14833.1 KPI37561.1 - 0.11 12.5 0.1 0.36 10.9 0.1 1.9 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PROCN PF08083.6 KPI37562.1 - 3e-210 697.8 8.8 3e-210 697.8 6.1 1.7 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KPI37562.1 - 8.3e-123 408.1 2.3 1.4e-122 407.3 1.6 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KPI37562.1 - 2.6e-94 312.9 1.0 6e-94 311.7 0.7 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KPI37562.1 - 4.1e-77 257.0 3.0 4.1e-77 257.0 2.1 2.2 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KPI37562.1 - 2.4e-66 221.4 0.2 6.2e-66 220.1 0.1 1.8 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 KPI37562.1 - 2.4e-45 152.3 0.2 6.9e-45 150.8 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 KPI37562.1 - 2.8e-39 133.6 0.0 9.9e-39 131.9 0.0 2.1 2 0 0 2 2 2 1 PROCT (NUC072) domain DUF3753 PF12575.3 KPI37562.1 - 0.098 12.4 0.1 0.28 11.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) zf-C2H2_4 PF13894.1 KPI37564.1 - 1.3e-05 25.1 20.8 0.04 14.2 0.3 5.7 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI37564.1 - 0.0031 17.7 24.3 0.22 11.9 0.2 6.6 6 1 0 6 6 6 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KPI37564.1 - 0.025 14.6 0.8 0.025 14.6 0.6 5.8 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding A2L_zn_ribbon PF08792.5 KPI37564.1 - 0.045 13.2 1.8 8.3 6.0 0.0 3.8 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-CHC2 PF01807.15 KPI37564.1 - 0.062 12.8 1.8 5.4 6.6 0.1 2.6 2 0 0 2 2 2 0 CHC2 zinc finger zf-C2H2_6 PF13912.1 KPI37564.1 - 0.96 9.4 6.5 2.1 8.3 1.0 3.6 2 1 0 2 2 2 0 C2H2-type zinc finger Rpr2 PF04032.11 KPI37564.1 - 1.4 8.8 5.1 1.5 8.7 0.3 2.9 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain TF_Zn_Ribbon PF08271.7 KPI37564.1 - 2.7 7.4 8.5 22 4.4 0.1 4.2 4 0 0 4 4 4 0 TFIIB zinc-binding CRCB PF02537.10 KPI37566.1 - 1.7e-26 92.4 16.4 4.6e-21 74.8 2.2 2.7 3 0 0 3 3 3 2 CrcB-like protein VHS PF00790.14 KPI37566.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 VHS domain DUF1275 PF06912.6 KPI37567.1 - 2.4e-38 131.4 7.2 3e-38 131.1 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_1 PF07690.11 KPI37567.1 - 5.5e-05 22.0 8.3 0.00017 20.4 0.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily NADH-u_ox-rdase PF10785.4 KPI37567.1 - 0.71 10.1 3.0 26 5.1 0.1 2.9 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF4231 PF14015.1 KPI37567.1 - 1.9 8.4 7.3 7.1 6.6 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Peptidase_S10 PF00450.17 KPI37568.1 - 3.3e-91 306.5 0.8 1e-59 202.7 0.3 2.1 1 1 1 2 2 2 2 Serine carboxypeptidase SKG6 PF08693.5 KPI37569.1 - 0.079 12.2 1.3 0.83 9.0 0.0 2.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF1211 PF06736.6 KPI37569.1 - 0.24 11.5 2.1 2.5 8.2 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1211) DUF1541 PF07563.6 KPI37569.1 - 0.66 9.6 2.7 1.4 8.6 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Fungal_lectin PF07938.7 KPI37571.1 - 0.00048 19.5 0.0 0.00053 19.3 0.0 1.1 1 0 0 1 1 1 1 Fungal fucose-specific lectin Arf PF00025.16 KPI37572.1 - 6.9e-38 129.6 0.0 6.9e-17 61.2 0.0 3.1 3 0 0 3 3 3 3 ADP-ribosylation factor family G-alpha PF00503.15 KPI37572.1 - 1.4e-11 43.7 0.0 3.3e-05 22.7 0.0 2.7 2 1 0 3 3 3 2 G-protein alpha subunit Ras PF00071.17 KPI37572.1 - 2.8e-05 23.5 0.0 0.11 11.8 0.0 3.1 3 0 0 3 3 3 2 Ras family MMR_HSR1 PF01926.18 KPI37572.1 - 4e-05 23.5 0.0 8.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KPI37572.1 - 4.3e-05 23.0 0.0 0.018 14.4 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KPI37572.1 - 0.00018 20.7 0.1 0.052 12.7 0.1 2.9 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KPI37572.1 - 0.00052 20.4 0.0 0.0063 16.9 0.0 2.4 2 1 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 KPI37572.1 - 0.0039 16.3 0.0 0.03 13.4 0.0 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KPI37572.1 - 0.063 12.5 0.1 0.61 9.3 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Aminotran_5 PF00266.14 KPI37573.1 - 8.1e-51 172.8 0.0 1.1e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MFS_1 PF07690.11 KPI37573.1 - 5.9e-23 81.1 52.9 1.1e-16 60.5 26.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cys_Met_Meta_PP PF01053.15 KPI37573.1 - 0.001 17.4 0.0 0.0016 16.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KPI37573.1 - 0.0011 18.0 0.1 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KPI37573.1 - 0.16 10.9 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Kelch_5 PF13854.1 KPI37574.1 - 7.6e-26 89.6 0.4 2.1e-06 27.5 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 KPI37574.1 - 2.9e-25 87.3 1.4 8.8e-06 25.6 0.0 4.6 2 1 2 4 4 4 4 Kelch motif Kelch_4 PF13418.1 KPI37574.1 - 8.8e-24 83.0 7.3 3.1e-06 26.8 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 KPI37574.1 - 8.8e-23 79.8 7.8 2.7e-08 33.7 0.0 5.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KPI37574.1 - 3.7e-21 74.0 1.1 4.7e-07 29.3 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.20 KPI37574.1 - 2.2e-20 71.9 1.2 8.9e-07 28.3 0.0 4.5 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 KPI37574.1 - 3.8e-10 39.7 0.1 7.6e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 KPI37574.1 - 0.065 13.0 0.0 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 BTB And C-terminal Kelch 2-Hacid_dh_C PF02826.14 KPI37575.1 - 4.4e-53 179.0 0.0 5.9e-53 178.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KPI37575.1 - 2.9e-20 72.0 0.0 3.3e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 KPI37575.1 - 1.3e-09 38.0 0.0 1.1e-05 25.3 0.1 2.3 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 KPI37575.1 - 0.00022 21.1 0.1 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KPI37575.1 - 0.00072 19.9 0.5 0.0015 18.9 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 KPI37575.1 - 0.11 11.8 0.1 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain V_ATPase_I PF01496.14 KPI37576.1 - 0.33 8.7 4.7 0.47 8.2 3.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4164 PF13747.1 KPI37576.1 - 0.41 10.8 13.2 1.6 8.8 3.5 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) SlyX PF04102.7 KPI37576.1 - 0.97 9.8 12.2 4.1 7.8 0.5 3.5 1 1 2 3 3 3 0 SlyX YlqD PF11068.3 KPI37576.1 - 1 9.3 11.3 0.16 12.0 4.7 1.8 2 0 0 2 2 2 0 YlqD protein APG6 PF04111.7 KPI37576.1 - 1.2 8.1 10.8 1.8 7.5 7.0 1.6 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF972 PF06156.8 KPI37576.1 - 1.6 9.1 7.8 13 6.1 0.0 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF4407 PF14362.1 KPI37576.1 - 2.7 6.8 5.9 18 4.1 4.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.8 KPI37576.1 - 3.3 8.4 6.9 0.86 10.3 0.1 2.8 2 1 1 3 3 3 0 Occludin homology domain Uds1 PF15456.1 KPI37576.1 - 3.7 7.5 9.9 2.2 8.2 0.2 3.0 1 1 3 4 4 4 0 Up-regulated During Septation TBPIP PF07106.8 KPI37576.1 - 4.7 6.7 10.4 0.71 9.3 4.1 1.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 KPI37576.1 - 4.8 6.7 16.5 0.44 10.1 4.1 2.5 1 1 1 2 2 2 0 IncA protein Mnd1 PF03962.10 KPI37576.1 - 5.3 6.6 9.6 0.77 9.3 3.5 1.8 2 0 0 2 2 2 0 Mnd1 family Cupin_1 PF00190.17 KPI37578.1 - 6.1e-10 38.6 0.1 9.3e-10 38.0 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 KPI37578.1 - 0.0054 16.1 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain DUF2186 PF09952.4 KPI37578.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2186) HATPase_c PF02518.21 KPI37579.1 - 1.5e-22 79.4 0.0 3.3e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 KPI37579.1 - 1e-14 54.7 0.0 2e-13 50.6 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 KPI37579.1 - 4.8e-13 48.8 0.0 1.9e-12 46.9 0.0 2.1 1 0 0 1 1 1 1 PAS fold Response_reg PF00072.19 KPI37579.1 - 3e-11 43.3 1.0 1.4e-10 41.1 0.2 2.6 2 1 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.6 KPI37579.1 - 3.1e-09 36.7 0.1 7.5e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 KPI37579.1 - 1.6e-08 34.5 0.0 1.5e-06 28.1 0.0 3.6 4 0 0 4 4 4 1 PAS fold HisKA PF00512.20 KPI37579.1 - 6.9e-08 32.3 3.2 3.7e-07 30.0 2.2 2.3 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.1 KPI37579.1 - 0.00071 19.3 0.1 0.0042 16.9 0.0 2.4 2 0 0 2 2 2 1 PAS domain GAF_2 PF13185.1 KPI37579.1 - 0.0011 19.5 0.0 0.072 13.5 0.0 3.6 3 0 0 3 3 3 1 GAF domain GAF_3 PF13492.1 KPI37579.1 - 0.0011 19.0 0.0 0.0036 17.3 0.0 1.9 1 0 0 1 1 1 1 GAF domain GA PF01468.12 KPI37579.1 - 0.051 13.7 0.5 0.1 12.7 0.4 1.5 1 0 0 1 1 1 0 GA module Piwi PF02171.12 KPI37580.1 - 8.6e-55 185.8 0.0 1.2e-54 185.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain Ribosomal_L34e PF01199.13 KPI37581.1 - 1.9e-23 82.4 7.0 1.9e-13 50.4 0.3 2.3 1 1 1 2 2 2 2 Ribosomal protein L34e Fungal_trans PF04082.13 KPI37583.1 - 3.2e-05 22.9 0.1 5.1e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI37583.1 - 5.5e-05 22.9 9.9 9.7e-05 22.1 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Erythro-docking PF09277.6 KPI37583.1 - 0.015 14.9 0.2 8.8 6.1 0.0 2.6 2 0 0 2 2 2 0 Erythronolide synthase, docking Cupin_1 PF00190.17 KPI37584.1 - 6.1e-33 113.2 0.0 1.1e-17 63.8 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KPI37584.1 - 5.7e-27 93.0 0.6 1.4e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KPI37584.1 - 1.3e-10 40.4 0.0 0.00058 19.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KPI37584.1 - 1.7e-07 31.0 0.2 0.0022 17.6 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.13 KPI37584.1 - 0.00023 20.8 0.0 0.0043 16.6 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.9 KPI37584.1 - 0.00095 19.1 0.2 0.022 14.6 0.0 2.3 2 0 0 2 2 2 1 ARD/ARD' family Cupin_6 PF12852.2 KPI37584.1 - 0.0013 18.3 0.0 0.24 10.9 0.0 2.2 2 0 0 2 2 2 2 Cupin FdtA PF05523.6 KPI37584.1 - 0.0027 17.1 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 2 WxcM-like, C-terminal SRC-1 PF08832.5 KPI37584.1 - 0.0033 18.1 0.4 2.4 8.9 0.0 2.4 2 0 0 2 2 2 2 Steroid receptor coactivator ketoacyl-synt PF00109.21 KPI37585.1 - 3.7e-19 69.2 0.0 8.3e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 KPI37585.1 - 1.1e-18 67.1 0.0 2.4e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 KPI37585.1 - 4.7e-10 39.3 0.0 1.1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KPI37585.1 - 6.7e-06 26.1 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI37585.1 - 0.0023 17.6 0.0 0.0053 16.4 0.0 1.6 1 0 0 1 1 1 1 KR domain DUF1479 PF07350.7 KPI37587.1 - 7.5e-09 34.5 0.0 0.00054 18.5 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) PhyH PF05721.8 KPI37587.1 - 1.9e-08 34.5 0.0 3.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.13 KPI37589.1 - 2e-10 40.0 0.7 3.1e-10 39.3 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI37589.1 - 4.3e-09 36.1 5.7 1.1e-08 34.7 3.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1352 PF07086.7 KPI37589.1 - 0.1 12.2 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1352) XLF PF09302.6 KPI37590.1 - 3.2e-10 40.0 0.1 1.2e-09 38.1 0.1 1.8 1 1 0 1 1 1 1 XLF (XRCC4-like factor) DUF2404 PF10296.4 KPI37591.1 - 0.0024 17.9 0.0 0.028 14.5 0.0 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Yae1_N PF09811.4 KPI37593.1 - 9.8e-08 31.3 3.9 1.8e-07 30.5 2.7 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal PGAP1 PF07819.8 KPI37593.1 - 0.079 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein YbaB_DNA_bd PF02575.11 KPI37593.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family MFS_1 PF07690.11 KPI37594.1 - 3.2e-28 98.4 29.6 4.1e-28 98.1 20.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_C14 PF00656.17 KPI37595.1 - 4.3e-14 52.8 0.0 5.9e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Caspase domain DNA_ligase_A_M PF01068.16 KPI37597.1 - 4.8e-49 166.4 0.5 2e-46 157.9 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KPI37597.1 - 5.3e-37 127.3 0.0 9.1e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KPI37597.1 - 1.9e-18 66.6 0.0 1.2e-17 64.0 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 KPI37597.1 - 0.062 12.9 0.1 0.82 9.3 0.0 2.2 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain Sugar_tr PF00083.19 KPI37598.1 - 2.3e-79 267.0 24.2 2.7e-79 266.8 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI37598.1 - 3.4e-24 85.2 24.7 3.5e-23 81.8 15.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TPR_16 PF13432.1 KPI37598.1 - 0.13 12.9 0.5 0.26 11.9 0.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat GST_N PF02798.15 KPI37600.1 - 4e-13 49.3 0.0 1.7e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KPI37600.1 - 4.3e-13 49.2 0.0 9.2e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI37600.1 - 4.4e-11 42.6 0.0 8.5e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KPI37600.1 - 7.4e-11 41.8 0.1 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KPI37600.1 - 0.0013 19.1 0.1 0.0024 18.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI37600.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Alk_phosphatase PF00245.15 KPI37602.1 - 1.1e-106 357.0 0.0 1.6e-106 356.5 0.0 1.4 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 KPI37602.1 - 0.00027 20.4 0.3 0.00043 19.7 0.2 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Histidinol_dh PF00815.15 KPI37603.1 - 6.2e-175 581.7 3.3 6.2e-175 581.7 2.3 1.4 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.13 KPI37603.1 - 7.9e-25 86.2 0.2 1.5e-24 85.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KPI37603.1 - 6e-11 42.4 2.2 7.4e-10 38.9 0.0 3.1 3 0 0 3 3 3 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 KPI37603.1 - 0.0053 16.6 0.3 0.012 15.5 0.2 1.6 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Lactamase_B_3 PF13483.1 KPI37604.1 - 1.4e-06 28.1 0.1 1.8e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 KPI37604.1 - 0.00011 21.8 0.3 0.00016 21.2 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Peptidase_C74 PF12387.3 KPI37605.1 - 0.51 9.4 4.9 0.67 9.0 3.4 1.1 1 0 0 1 1 1 0 Pestivirus NS2 peptidase DUF4337 PF14235.1 KPI37606.1 - 0.39 10.5 2.8 0.9 9.3 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) OPA3 PF07047.7 KPI37606.1 - 8.3 6.1 6.4 3 7.6 1.6 2.0 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) Acyl_transf_1 PF00698.16 KPI37607.1 - 1.8e-84 283.8 0.0 4e-80 269.5 0.0 2.7 3 0 0 3 3 3 2 Acyl transferase domain MaoC_dehydratas PF01575.14 KPI37607.1 - 1.4e-39 134.2 0.0 3.5e-39 132.9 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 KPI37607.1 - 4.2e-32 109.7 0.1 1.3e-31 108.1 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 KPI37607.1 - 3.9e-21 75.2 0.1 3.2e-20 72.2 0.0 2.6 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase NMO PF03060.10 KPI37607.1 - 0.00029 20.1 0.2 0.13 11.3 0.1 2.5 2 0 0 2 2 2 2 Nitronate monooxygenase TRP PF06011.7 KPI37608.1 - 5.5e-86 288.8 18.5 9.4e-85 284.7 12.8 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KPI37608.1 - 7.8e-18 64.8 0.0 1.3e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Pyr_redox_3 PF13738.1 KPI37609.1 - 5.5e-14 52.6 0.0 3e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI37609.1 - 3e-11 42.8 0.0 2.4e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KPI37609.1 - 8e-09 34.2 0.0 1.7e-08 33.1 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like adh_short PF00106.20 KPI37610.1 - 6.7e-16 58.6 0.0 1.4e-08 34.8 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KPI37610.1 - 5.7e-07 29.3 0.1 0.011 15.4 0.1 2.8 2 1 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KPI37610.1 - 1.8e-06 27.9 0.0 0.00017 21.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF3498 PF12004.3 KPI37610.1 - 2.2 7.3 8.6 0.15 11.1 2.7 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3498) VSP PF03302.8 KPI37613.1 - 0.0096 14.6 0.2 0.012 14.2 0.1 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.6 KPI37613.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Podoplanin Syndecan PF01034.15 KPI37613.1 - 0.18 11.4 1.2 0.33 10.6 0.8 1.3 1 0 0 1 1 1 0 Syndecan domain DUF1049 PF06305.6 KPI37613.1 - 0.25 10.8 0.9 0.41 10.1 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF4267 PF14087.1 KPI37614.1 - 8e-23 80.1 2.1 9.7e-23 79.9 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF4149 PF13664.1 KPI37614.1 - 0.11 12.5 0.3 0.32 11.0 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) DUF221 PF02714.10 KPI37615.1 - 3.8e-105 351.3 10.9 6e-105 350.6 7.6 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF3779 PF12621.3 KPI37615.1 - 8.6e-21 73.6 0.1 1.9e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein RSN1_TM PF13967.1 KPI37615.1 - 1.1e-12 47.8 0.0 1.1e-12 47.8 0.0 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KPI37615.1 - 2e-07 31.4 0.0 6.7e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF4446 PF14584.1 KPI37615.1 - 0.008 16.0 0.0 8 6.2 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF4446) TMF_DNA_bd PF12329.3 KPI37615.1 - 0.046 13.5 4.5 0.068 12.9 0.0 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RRM_6 PF14259.1 KPI37615.1 - 0.088 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cytomega_TRL10 PF06084.6 KPI37615.1 - 3.1 7.5 4.2 6 6.6 0.1 2.5 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein adh_short PF00106.20 KPI37616.1 - 1.5e-21 77.0 0.1 2.3e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI37616.1 - 1.2e-19 71.0 0.0 1.6e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI37616.1 - 1.2e-09 38.0 0.0 2.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI37616.1 - 0.0019 17.6 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AA_permease PF00324.16 KPI37617.1 - 4.8e-108 361.5 42.4 5.4e-108 361.3 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI37617.1 - 2.7e-28 98.6 50.2 3.2e-28 98.4 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease FUSC-like PF12805.2 KPI37617.1 - 0.5 9.2 1.1 0.93 8.3 0.8 1.4 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Ribosomal_S21e PF01249.13 KPI37618.1 - 1.6e-41 140.1 0.1 1.8e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e tRNA-synt_1g PF09334.6 KPI37619.1 - 9e-142 472.3 0.0 1.3e-141 471.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KPI37619.1 - 3.6e-08 31.9 0.9 1.7e-05 23.0 0.0 3.4 3 1 1 4 4 4 2 tRNA synthetases class I (I, L, M and V) DUF2201_N PF13203.1 KPI37619.1 - 0.028 13.6 0.3 0.042 13.0 0.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DZR PF12773.2 KPI37619.1 - 0.057 13.2 2.7 0.14 12.0 1.9 1.7 1 0 0 1 1 1 0 Double zinc ribbon NARP1 PF12569.3 KPI37619.1 - 3.2 6.3 9.0 5.1 5.7 6.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AA_permease_2 PF13520.1 KPI37620.1 - 9e-81 271.5 28.3 1.1e-80 271.2 19.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI37620.1 - 3.2e-26 91.7 22.9 4.3e-26 91.3 15.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2347 PF09804.4 KPI37621.1 - 3.3e-93 312.0 0.0 4.3e-93 311.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 KPI37621.1 - 3.3e-39 134.7 4.4 8.3e-39 133.4 3.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 KPI37621.1 - 1.1e-06 28.3 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KPI37621.1 - 6.9e-05 21.5 0.1 0.056 11.9 0.0 2.5 2 1 1 3 3 3 2 Transport protein Avl9 RNA_pol_Rpb1_5 PF04998.12 KPI37623.1 - 2.2e-98 328.9 0.0 3.2e-98 328.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KPI37623.1 - 8.7e-70 233.9 0.0 1.7e-69 233.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KPI37623.1 - 1.2e-56 191.4 0.2 3e-56 190.1 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 KPI37623.1 - 2.7e-46 157.1 0.0 5.1e-46 156.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KPI37623.1 - 6.5e-38 129.4 2.8 1.2e-37 128.6 1.9 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KPI37623.1 - 1.7e-32 111.3 0.7 4.1e-32 110.1 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 KPI37623.1 - 4.3e-12 45.0 226.6 0.013 15.5 6.4 14.9 12 1 3 15 15 15 12 RNA polymerase Rpb1 C-terminal repeat RNA_pol_Rpb1_1 PF04997.7 KPI37623.1 - 1.1e-10 41.2 1.0 1.7e-10 40.6 0.7 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 Kinesin PF00225.18 KPI37624.1 - 9.4e-114 379.5 0.0 1.3e-113 379.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain AAA_33 PF13671.1 KPI37624.1 - 0.02 14.7 0.0 0.081 12.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF605 PF04652.11 KPI37624.1 - 1.8 7.8 22.0 3.4 6.9 15.3 1.4 1 0 0 1 1 1 0 Vta1 like Enolase_C PF00113.17 KPI37625.1 - 1.2e-112 375.7 0.0 1.5e-112 375.3 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KPI37625.1 - 9.1e-47 158.3 0.2 1.4e-46 157.6 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 KPI37625.1 - 0.029 14.9 0.0 0.096 13.2 0.0 2.0 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 KPI37625.1 - 0.036 14.0 0.0 0.097 12.6 0.0 1.7 1 0 0 1 1 1 0 Enolase C-terminal domain-like fn1 PF00039.13 KPI37625.1 - 0.13 12.0 0.2 0.46 10.3 0.0 1.9 2 0 0 2 2 2 0 Fibronectin type I domain Pkinase PF00069.20 KPI37627.1 - 1.2e-69 234.3 0.0 5.2e-69 232.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI37627.1 - 1.4e-48 165.2 0.0 2.4e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI37627.1 - 0.0039 16.2 0.0 0.012 14.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FYVE PF01363.16 KPI37629.1 - 1.2e-20 73.1 5.6 1.2e-20 73.1 3.9 2.9 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 KPI37629.1 - 2.6e-10 39.9 5.3 2.6e-10 39.9 3.7 3.5 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 KPI37629.1 - 2.6e-05 24.2 3.1 2.6e-05 24.2 2.2 3.1 3 0 0 3 3 3 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KPI37629.1 - 0.0041 16.9 2.9 0.017 14.9 1.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KPI37629.1 - 0.0097 15.5 4.0 0.0097 15.5 2.8 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KPI37629.1 - 0.014 15.3 4.7 0.028 14.3 1.8 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain zf-DHHC PF01529.15 KPI37629.1 - 0.18 11.2 3.2 0.57 9.5 2.2 1.9 1 0 0 1 1 1 0 DHHC palmitoyltransferase zf-C2H2_3 PF13878.1 KPI37629.1 - 4.1 7.0 7.3 5.4 6.6 0.0 3.0 2 1 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO FYVE_2 PF02318.11 KPI37629.1 - 9 6.2 9.6 0.16 11.8 1.6 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger Membr_traf_MHD PF10540.4 KPI37630.1 - 1.2e-27 96.4 0.1 3.7e-27 94.7 0.0 1.9 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KPI37630.1 - 3.3e-16 58.9 0.2 2.6e-15 56.0 0.0 2.4 2 0 0 2 2 2 1 C2 domain DUF810 PF05664.6 KPI37630.1 - 4.8e-05 21.8 1.5 0.00022 19.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF810) K_channel_TID PF07941.6 KPI37630.1 - 0.91 9.8 7.8 0.7 10.1 0.8 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Oxidored_FMN PF00724.15 KPI37632.1 - 8.8e-56 189.3 0.0 4.4e-37 127.8 0.0 3.0 2 1 1 3 3 3 3 NADH:flavin oxidoreductase / NADH oxidase family Ferric_reduct PF01794.14 KPI37633.1 - 4.7e-21 75.1 8.1 1.1e-20 73.9 5.6 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KPI37633.1 - 2e-18 66.7 0.0 4.4e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KPI37633.1 - 1.2e-11 44.3 0.0 2.4e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KPI37633.1 - 0.018 15.6 0.0 0.048 14.2 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain MFS_1 PF07690.11 KPI37634.1 - 3.2e-10 39.2 27.0 3.2e-10 39.2 18.7 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Pro_dh PF01619.13 KPI37635.1 - 1.3e-35 122.9 0.9 1.7e-35 122.5 0.7 1.1 1 0 0 1 1 1 1 Proline dehydrogenase INO80_Ies4 PF08193.6 KPI37636.1 - 2.9e-47 161.4 17.8 2.9e-47 161.4 12.3 1.4 1 1 1 2 2 2 1 INO80 complex subunit Ies4 RAP1 PF07218.6 KPI37638.1 - 0.0057 14.8 0.2 0.007 14.5 0.2 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) DUF4613 PF15390.1 KPI37638.1 - 0.014 13.5 0.8 0.02 13.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Serine_rich PF08824.5 KPI37638.1 - 0.028 14.1 1.3 0.041 13.5 0.9 1.3 1 0 0 1 1 1 0 Serine rich protein interaction domain SNF2_N PF00176.18 KPI37639.1 - 5.9e-65 219.0 0.0 8e-65 218.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KPI37639.1 - 2.9e-14 52.6 0.0 6.2e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI37639.1 - 0.00021 21.1 0.0 0.00053 19.8 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KPI37639.1 - 0.17 10.8 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 KPI37640.1 - 1.7e-12 47.7 0.0 3.8e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KPI37640.1 - 5.5e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KPI37640.1 - 2.2e-05 24.1 0.0 5.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KPI37640.1 - 5.7e-05 22.7 0.0 0.0002 21.0 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KPI37640.1 - 6.7e-05 22.0 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KPI37640.1 - 0.00025 20.9 0.0 0.00051 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KPI37640.1 - 0.00035 19.3 0.0 0.00056 18.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 KPI37640.1 - 0.00067 20.4 0.1 0.0018 19.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KPI37640.1 - 0.00074 18.6 0.6 0.0014 17.7 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 KPI37640.1 - 0.00079 19.4 0.0 0.0036 17.3 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KPI37640.1 - 0.00082 19.2 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 KPI37640.1 - 0.0023 17.3 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 KPI37640.1 - 0.0055 16.1 0.2 0.014 14.8 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF258 PF03193.11 KPI37640.1 - 0.015 14.4 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 KPI37640.1 - 0.021 15.1 0.1 0.052 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KPI37640.1 - 0.029 14.1 0.0 0.074 12.7 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.1 KPI37640.1 - 0.073 12.6 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 KPI37640.1 - 0.079 11.8 0.1 0.22 10.3 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Pyr_redox_3 PF13738.1 KPI37641.1 - 2.3e-25 89.8 0.1 1.4e-24 87.3 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI37641.1 - 7.7e-14 50.7 0.0 1.2e-12 46.8 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KPI37641.1 - 7.9e-08 31.5 0.1 2.2e-06 26.8 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KPI37641.1 - 4.8e-07 29.7 0.1 1.6e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KPI37641.1 - 0.0041 16.9 0.6 0.082 12.6 0.1 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KPI37641.1 - 0.01 14.7 0.1 2.8 6.7 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase AP_endonuc_2 PF01261.19 KPI37642.1 - 1.1e-26 93.4 0.0 2.3e-26 92.3 0.0 1.5 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel SLAC1 PF03595.12 KPI37643.1 - 4.9e-84 281.7 51.8 5.9e-84 281.5 35.9 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF2207 PF09972.4 KPI37643.1 - 0.034 12.7 0.1 0.034 12.7 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF1003 PF06210.6 KPI37643.1 - 1 9.3 0.0 1 9.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1003) Peptidase_C8 PF03569.8 KPI37644.1 - 0.03 13.6 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C8 PMSR PF01625.16 KPI37645.1 - 1.1e-56 191.0 0.4 1.3e-56 190.7 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase LysM PF01476.15 KPI37646.1 - 2e-06 27.5 0.0 5.6e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 LysM domain Mucin PF01456.12 KPI37646.1 - 0.13 12.0 17.2 0.33 10.7 11.9 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein NAD_binding_2 PF03446.10 KPI37647.1 - 2.1e-25 89.4 0.0 2.7e-23 82.6 0.0 2.1 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KPI37647.1 - 7e-24 84.2 0.0 1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KPI37647.1 - 0.0039 17.5 0.0 0.0078 16.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent U3_assoc_6 PF08640.6 KPI37647.1 - 0.067 12.9 0.0 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 Abhydrolase_6 PF12697.2 KPI37648.1 - 1.1e-10 41.7 1.3 3.7e-10 40.0 0.9 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family RNase_PH PF01138.16 KPI37649.1 - 7.6e-37 126.5 1.3 1.7e-36 125.4 0.3 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RTA1 PF04479.8 KPI37650.1 - 5.2e-48 163.4 5.5 7.5e-48 162.9 3.8 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4271 PF14093.1 KPI37650.1 - 0.53 9.9 12.6 0.036 13.7 1.5 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4271) MFS_1 PF07690.11 KPI37651.1 - 3.4e-38 131.2 30.3 3.4e-38 131.2 21.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF912 PF06024.7 KPI37651.1 - 0.0029 17.6 0.0 0.0087 16.1 0.0 1.8 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Glyco_hydro_72 PF03198.9 KPI37653.1 - 3.1e-69 233.3 0.0 4.2e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KPI37653.1 - 0.045 12.9 0.0 0.081 12.1 0.0 1.5 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Arrestin_N PF00339.24 KPI37654.1 - 5.9e-09 35.8 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Ctr PF04145.10 KPI37655.1 - 1.6e-41 141.7 0.6 1.8e-41 141.5 0.4 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Sensor PF13796.1 KPI37655.1 - 0.035 13.7 5.5 0.56 9.7 0.2 2.5 1 1 0 2 2 2 0 Putative sensor Sulfotransfer_3 PF13469.1 KPI37656.1 - 6e-08 33.7 0.7 3.4e-07 31.3 0.5 2.0 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 KPI37656.1 - 0.026 13.8 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain Ras PF00071.17 KPI37657.1 - 7.5e-65 217.2 0.0 8.7e-65 217.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KPI37657.1 - 3.5e-19 69.4 0.0 4.6e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KPI37657.1 - 5.4e-13 48.5 0.0 6.6e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KPI37657.1 - 5.6e-06 25.6 0.0 7.1e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KPI37657.1 - 1.3e-05 24.7 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KPI37657.1 - 0.0055 16.6 0.0 0.0076 16.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KPI37657.1 - 0.024 13.8 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KPI37657.1 - 0.097 11.9 0.0 0.37 10.0 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 KPI37657.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MOSC PF03473.12 KPI37659.1 - 3.5e-12 45.9 0.0 7.5e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 KPI37659.1 - 3.4e-11 42.9 0.0 2.1e-10 40.3 0.0 2.1 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain ORC2 PF04084.9 KPI37661.1 - 1.1e-97 326.7 0.0 1.3e-97 326.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ORC6 PF05460.8 KPI37661.1 - 0.15 11.1 15.0 0.23 10.5 10.0 1.6 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) AT_hook PF02178.14 KPI37661.1 - 0.91 9.4 7.5 2.6 8.0 5.2 1.8 1 0 0 1 1 1 0 AT hook motif RAP1 PF07218.6 KPI37661.1 - 1.1 7.2 4.3 1.6 6.7 3.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Rox3 PF08633.5 KPI37662.1 - 9.7e-34 117.3 0.2 9.7e-34 117.3 0.1 2.3 2 1 0 2 2 2 1 Rox3 mediator complex subunit ORC6 PF05460.8 KPI37662.1 - 0.095 11.7 14.6 0.019 14.1 7.8 1.5 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) SGL PF08450.7 KPI37663.1 - 5.5e-20 71.7 0.8 1e-19 70.8 0.6 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 KPI37663.1 - 0.0025 17.6 2.4 2.6 8.1 0.1 4.0 4 0 0 4 4 4 2 NHL repeat Alpha-L-AF_C PF06964.7 KPI37664.1 - 2.3e-27 95.9 0.0 3.4e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 KPI37664.1 - 0.0015 18.5 0.5 0.0034 17.3 0.4 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain Extensin-like_C PF06904.7 KPI37665.1 - 0.098 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Extensin-like protein C-terminus Abhydrolase_3 PF07859.8 KPI37666.1 - 6e-38 130.5 0.0 8.2e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI37666.1 - 4.8e-05 22.6 0.1 0.2 10.8 0.1 3.0 3 1 0 3 3 3 2 Prolyl oligopeptidase family COesterase PF00135.23 KPI37666.1 - 0.00013 20.8 0.8 0.00016 20.5 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KPI37666.1 - 0.0017 18.0 0.0 0.0032 17.2 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI37666.1 - 0.0055 16.6 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family ADC PF06314.6 KPI37666.1 - 0.029 13.7 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) Abhydrolase_2 PF02230.11 KPI37666.1 - 0.17 11.3 0.2 0.35 10.2 0.2 1.4 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF904 PF06005.7 KPI37667.1 - 0.031 14.5 2.0 2.2 8.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) GvpG PF05120.7 KPI37667.1 - 0.15 11.8 2.0 0.28 11.0 0.2 2.2 2 0 0 2 2 2 0 Gas vesicle protein G Phage_Mu_Gam PF07352.7 KPI37667.1 - 0.22 11.0 3.7 0.26 10.8 0.3 2.4 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein TetR_C_6 PF13977.1 KPI37667.1 - 0.31 11.0 2.8 2.5 8.1 0.5 2.8 2 1 1 3 3 3 0 Bacterial transcriptional repressor Tup_N PF08581.5 KPI37667.1 - 0.71 10.1 4.5 2.1 8.6 0.1 3.0 3 0 0 3 3 3 0 Tup N-terminal HR1 PF02185.11 KPI37667.1 - 5 6.9 7.5 3.9 7.2 0.3 2.8 2 1 0 2 2 2 0 Hr1 repeat EF1G PF00647.14 KPI37668.1 - 2.6e-44 149.3 0.1 4.4e-44 148.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 KPI37668.1 - 1.3e-08 34.8 0.1 5e-07 29.7 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KPI37668.1 - 8.1e-07 29.1 0.3 2.1e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KPI37668.1 - 1.1e-06 28.5 0.0 3.7e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI37668.1 - 3.1e-05 23.7 0.1 7.1e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KPI37668.1 - 0.029 14.8 0.0 0.081 13.4 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KPI37668.1 - 0.035 14.0 0.2 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain SAC3_GANP PF03399.11 KPI37669.1 - 3.6e-44 150.7 0.0 7.6e-44 149.7 0.0 1.6 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family GTP_EFTU PF00009.22 KPI37670.1 - 1.2e-37 129.1 0.0 2.2e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KPI37670.1 - 5.5e-24 83.8 0.0 1.3e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KPI37670.1 - 7.6e-17 60.9 0.0 2.3e-15 56.2 0.0 2.5 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KPI37670.1 - 7.6e-10 38.7 0.0 1.1e-08 35.0 0.0 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KPI37670.1 - 0.0074 16.2 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Epimerase PF01370.16 KPI37671.1 - 1.8e-12 47.1 0.2 2.1e-10 40.4 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI37671.1 - 8.6e-08 31.2 0.0 1.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KPI37671.1 - 9.7e-07 28.9 0.1 2.7e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KPI37671.1 - 0.0091 14.9 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KPI37671.1 - 0.011 15.6 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 KPI37671.1 - 0.038 13.6 0.4 0.082 12.5 0.3 1.6 1 1 0 1 1 1 0 KR domain NmrA PF05368.8 KPI37671.1 - 0.049 12.8 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family NUDIX PF00293.23 KPI37672.1 - 1.8e-13 50.2 0.2 2.7e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 KPI37672.1 - 0.017 14.5 0.1 0.062 12.7 0.1 1.8 1 1 0 1 1 1 0 NUDIX domain Aldedh PF00171.17 KPI37673.1 - 3.4e-154 513.6 0.6 3.8e-154 513.4 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pyr_redox_3 PF13738.1 KPI37674.1 - 5e-16 59.3 0.0 2.1e-15 57.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI37674.1 - 2.7e-13 48.9 0.0 4.8e-12 44.8 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI37674.1 - 1e-08 35.0 0.0 5.7e-08 32.6 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI37674.1 - 2.5e-05 23.3 0.2 0.00017 20.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KPI37674.1 - 0.00087 18.2 0.0 0.37 9.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KPI37674.1 - 0.0055 16.4 0.0 1.2 8.9 0.0 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding DUF3176 PF11374.3 KPI37675.1 - 3.4e-26 91.2 4.5 3.4e-26 91.2 3.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) NUDIX PF00293.23 KPI37677.1 - 5.4e-08 32.5 0.1 1.4e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain DUF1649 PF07855.7 KPI37678.1 - 2.8e-41 140.9 0.0 8.6e-41 139.3 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1649) SPARC_Ca_bdg PF10591.4 KPI37679.1 - 0.058 13.4 3.2 0.35 10.9 2.0 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Rad21_Rec8_N PF04825.8 KPI37680.1 - 1.4e-20 73.3 0.0 2.1e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KPI37680.1 - 0.025 13.7 0.0 0.061 12.5 0.0 1.6 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein Reo_sigmaC PF04582.7 KPI37681.1 - 0.48 9.5 37.4 0.3 10.2 1.8 5.4 1 1 3 5 5 5 0 Reovirus sigma C capsid protein Sugar_tr PF00083.19 KPI37682.1 - 3.6e-73 246.6 27.6 4.3e-73 246.4 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI37682.1 - 3.5e-14 52.2 36.5 5.8e-13 48.2 24.0 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI37682.1 - 0.00043 18.7 28.9 0.0036 15.7 3.2 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein DUF1056 PF06341.6 KPI37682.1 - 0.019 14.9 0.1 0.019 14.9 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1056) Aa_trans PF01490.13 KPI37683.1 - 3.8e-64 216.6 13.0 4.7e-64 216.3 9.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KPI37683.1 - 0.00015 20.6 9.2 0.00015 20.6 6.4 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Cyclase PF04199.8 KPI37684.1 - 1.1e-18 67.5 0.0 1.9e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase BicD PF09730.4 KPI37684.1 - 0.0035 15.7 4.2 0.0048 15.3 2.9 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D DUF641 PF04859.7 KPI37684.1 - 0.028 14.1 1.3 0.058 13.1 0.9 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) IncA PF04156.9 KPI37684.1 - 0.25 10.9 3.7 0.51 9.9 2.6 1.5 1 0 0 1 1 1 0 IncA protein DivIVA PF05103.8 KPI37684.1 - 0.78 9.8 6.4 0.43 10.6 2.9 1.6 2 0 0 2 2 2 0 DivIVA protein TMF_DNA_bd PF12329.3 KPI37684.1 - 1.5 8.7 8.1 1.5 8.7 4.2 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 KPI37684.1 - 4.6 7.2 8.3 1.1 9.2 3.2 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ferric_reduct PF01794.14 KPI37685.1 - 4.6e-16 59.0 11.9 4.6e-16 59.0 8.2 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KPI37685.1 - 2.9e-11 43.5 0.0 6.5e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KPI37685.1 - 3.7e-11 42.8 0.0 7.9e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain DUF3824 PF12868.2 KPI37685.1 - 3.2 8.6 13.2 0.65 10.9 6.1 2.2 2 1 0 2 2 2 0 Domain of unknwon function (DUF3824) TMF_DNA_bd PF12329.3 KPI37686.1 - 0.023 14.5 0.4 0.035 13.9 0.3 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 KPI37686.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Zn_clus PF00172.13 KPI37687.1 - 2.7e-07 30.3 8.4 4.6e-07 29.6 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KPI37687.1 - 0.014 14.0 0.0 0.018 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain CoA_transf_3 PF02515.12 KPI37688.1 - 2.6e-40 137.7 0.0 1.6e-37 128.6 0.1 2.3 2 0 0 2 2 2 2 CoA-transferase family III DUF4387 PF14330.1 KPI37688.1 - 1.8e-35 121.2 0.0 3.7e-35 120.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 KPI37688.1 - 2.7e-19 68.8 0.0 5.7e-18 64.5 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) TAT_ubiq PF07706.7 KPI37688.1 - 0.12 12.2 0.9 0.27 11.1 0.6 1.6 1 0 0 1 1 1 0 Aminotransferase ubiquitination site Reo_sigmaC PF04582.7 KPI37689.1 - 0.038 13.1 17.8 0.13 11.4 4.6 3.5 3 1 0 3 3 3 0 Reovirus sigma C capsid protein DUF4080 PF13311.1 KPI37689.1 - 2.8 7.9 11.5 0.53 10.2 4.8 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4080) NIF PF03031.13 KPI37690.1 - 1.5e-10 40.9 0.3 3.2e-10 39.8 0.2 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase 2-Hacid_dh_C PF02826.14 KPI37691.1 - 5.4e-51 172.2 0.0 9.5e-51 171.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KPI37691.1 - 5.1e-36 123.0 0.1 6.9e-36 122.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain UDPG_MGDP_dh_N PF03721.9 KPI37691.1 - 0.00021 20.7 0.9 0.56 9.5 0.1 2.5 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 KPI37691.1 - 0.0011 18.8 0.1 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KPI37691.1 - 0.0046 16.3 0.0 0.014 14.7 0.0 1.8 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 KPI37691.1 - 0.01 15.6 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 KPI37691.1 - 0.017 14.6 0.1 0.058 12.8 0.0 2.0 2 0 0 2 2 2 0 ACT domain PAR1 PF06521.6 KPI37691.1 - 0.019 14.5 0.2 0.04 13.5 0.1 1.5 1 0 0 1 1 1 0 PAR1 protein 3HCDH_N PF02737.13 KPI37691.1 - 0.04 13.5 0.1 0.39 10.3 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 KPI37692.1 - 6.6e-07 29.3 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI37692.1 - 5.9e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI37692.1 - 0.03 14.3 0.1 2.5 8.0 0.1 2.2 2 0 0 2 2 2 0 NADH(P)-binding DUF258 PF03193.11 KPI37692.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 adh_short_C2 PF13561.1 KPI37693.1 - 1.9e-38 132.6 0.1 2.2e-38 132.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI37693.1 - 3.9e-29 101.6 2.5 6.1e-29 101.0 1.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI37693.1 - 2.3e-10 40.4 0.5 3.3e-10 39.9 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI37693.1 - 2.4e-05 23.9 0.4 5.6e-05 22.6 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KPI37693.1 - 0.0011 17.9 0.1 0.0015 17.4 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KPI37693.1 - 0.0067 16.1 1.8 0.011 15.4 0.6 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.14 KPI37693.1 - 0.02 13.6 0.2 0.034 12.8 0.1 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 KPI37693.1 - 0.035 13.7 0.3 0.075 12.6 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AA_kinase PF00696.23 KPI37693.1 - 0.061 12.8 0.5 0.16 11.5 0.3 1.5 1 1 0 1 1 1 0 Amino acid kinase family Methyltransf_25 PF13649.1 KPI37693.1 - 0.065 13.5 0.1 0.24 11.7 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain NAD_binding_3 PF03447.11 KPI37693.1 - 0.069 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain TrkA_N PF02254.13 KPI37693.1 - 0.07 13.1 0.1 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Dak1_2 PF13684.1 KPI37693.1 - 0.072 12.0 0.1 1.4 7.7 0.0 1.9 1 1 1 2 2 2 0 Dihydroxyacetone kinase family Abhydrolase_6 PF12697.2 KPI37695.1 - 6.1e-30 104.7 0.4 7.9e-30 104.4 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI37695.1 - 1e-12 48.0 0.0 4.1e-12 46.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI37695.1 - 4.1e-12 46.1 0.0 3.8e-11 42.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KPI37695.1 - 5.3e-08 32.6 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydro_lipase PF04083.11 KPI37695.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region SnoaL_2 PF12680.2 KPI37696.1 - 0.021 15.2 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain 2-Hacid_dh_C PF02826.14 KPI37697.1 - 4.9e-51 172.3 0.0 1e-50 171.3 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KPI37697.1 - 9.9e-16 57.4 0.0 1.5e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KPI37697.1 - 0.0029 17.4 0.0 0.0083 15.9 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase CTDII PF01556.13 KPI37698.1 - 7.3e-23 80.2 0.6 1.2e-17 63.5 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KPI37698.1 - 6.7e-22 77.0 1.4 1.3e-21 76.0 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KPI37698.1 - 2.3e-14 53.1 18.7 4.1e-14 52.3 13.0 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KPI37698.1 - 0.24 11.1 11.8 0.75 9.5 1.7 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Fungal_trans PF04082.13 KPI37700.1 - 4.9e-20 71.4 0.0 9.6e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI37700.1 - 1.9e-09 37.2 9.5 3.7e-09 36.3 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Striatin PF08232.7 KPI37700.1 - 0.072 13.4 3.8 0.55 10.5 2.0 2.5 2 1 0 2 2 2 0 Striatin family IncA PF04156.9 KPI37700.1 - 0.48 10.0 2.9 1 8.9 2.0 1.5 1 0 0 1 1 1 0 IncA protein Pox_A_type_inc PF04508.7 KPI37700.1 - 7.3 6.6 6.8 29 4.7 0.1 3.5 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat Zn_clus PF00172.13 KPI37701.1 - 8.6e-10 38.3 12.6 1.7e-09 37.4 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KPI37701.1 - 0.00091 18.1 0.0 0.0023 16.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain BNR_2 PF13088.1 KPI37702.1 - 4.7e-07 29.3 0.1 0.00013 21.4 0.0 2.3 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 KPI37702.1 - 7.3 6.8 17.2 2.8 8.1 0.1 4.7 5 0 0 5 5 5 0 BNR/Asp-box repeat K_oxygenase PF13434.1 KPI37703.1 - 1.3e-13 50.5 0.0 1.7e-08 33.7 0.0 2.9 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KPI37703.1 - 3e-12 47.0 0.0 0.00024 21.2 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI37703.1 - 1.1e-05 25.4 0.0 0.084 12.7 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KPI37703.1 - 0.0001 21.4 4.7 0.068 12.2 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain Shikimate_DH PF01488.15 KPI37703.1 - 0.00016 21.8 0.0 0.046 13.8 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KPI37703.1 - 0.00029 21.1 0.1 0.082 13.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI37703.1 - 0.00071 19.5 0.9 0.11 12.5 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KPI37703.1 - 0.0014 17.6 0.0 0.033 13.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 KPI37703.1 - 0.0067 16.1 0.0 4.1 7.1 0.0 2.3 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 KPI37703.1 - 0.0086 15.0 1.7 2.2 7.0 0.3 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KPI37703.1 - 0.011 15.5 1.6 0.15 11.7 0.0 3.1 3 1 1 4 4 4 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KPI37703.1 - 0.025 13.0 0.0 0.45 8.9 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.11 KPI37703.1 - 0.04 13.3 0.0 9.2 5.6 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 KPI37703.1 - 0.067 13.1 0.0 9.1 6.3 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.13 KPI37703.1 - 0.2 11.2 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KPI37703.1 - 0.22 10.6 0.2 0.47 9.4 0.0 1.6 2 0 0 2 2 2 0 Thi4 family CinA PF02464.12 KPI37704.1 - 5.6e-23 81.0 1.8 3.6e-16 58.9 0.1 2.0 1 1 1 2 2 2 2 Competence-damaged protein MFS_1 PF07690.11 KPI37705.1 - 1.8e-30 105.8 26.3 1.8e-30 105.8 18.2 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily PUCC PF03209.10 KPI37705.1 - 0.00092 18.0 4.0 0.0023 16.7 2.7 1.6 1 0 0 1 1 1 1 PUCC protein DUF3390 PF11870.3 KPI37705.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) DUF1228 PF06779.9 KPI37705.1 - 0.073 13.1 1.9 0.62 10.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) DUF947 PF06102.7 KPI37706.1 - 6.3e-32 110.7 15.3 9.5e-32 110.1 10.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF947) vMSA PF00695.14 KPI37706.1 - 0.087 12.0 1.5 0.12 11.5 0.6 1.5 1 1 0 1 1 1 0 Major surface antigen from hepadnavirus RVT_N PF13655.1 KPI37706.1 - 0.099 12.7 1.2 0.2 11.7 0.8 1.5 1 0 0 1 1 1 0 N-terminal domain of reverse transcriptase RBM1CTR PF08081.6 KPI37706.1 - 0.15 11.8 0.4 0.15 11.8 0.3 3.2 3 0 0 3 3 3 0 RBM1CTR (NUC064) family L51_S25_CI-B8 PF05047.11 KPI37707.1 - 1.2e-13 50.5 0.0 1.7e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Beta_helix PF13229.1 KPI37708.1 - 3.4e-13 49.6 14.6 2.4e-07 30.6 5.5 2.4 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.8 KPI37708.1 - 9.2e-10 38.0 6.0 0.002 17.2 2.2 3.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.6 KPI37708.1 - 0.0009 18.4 15.4 0.0018 17.4 4.3 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF1565) PT-VENN PF04829.8 KPI37708.1 - 7.9 6.1 10.2 1.5 8.3 0.1 4.1 4 0 0 4 4 4 0 Pre-toxin domain with VENN motif RF-1 PF00472.15 KPI37709.1 - 6.4e-24 83.9 0.3 9.7e-24 83.3 0.2 1.3 1 0 0 1 1 1 1 RF-1 domain CD99L2 PF12301.3 KPI37712.1 - 0.0014 18.3 0.2 0.0023 17.6 0.1 1.3 1 0 0 1 1 1 1 CD99 antigen like protein 2 DUF2537 PF10801.3 KPI37712.1 - 2 8.5 6.1 0.36 10.9 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) GFA PF04828.9 KPI37713.1 - 4.7e-23 80.9 0.2 5.4e-23 80.7 0.2 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Pkinase PF00069.20 KPI37714.1 - 1.5e-56 191.4 0.0 1.2e-55 188.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI37714.1 - 6.3e-29 100.8 0.0 7.8e-20 71.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KPI37714.1 - 1.1e-07 32.1 0.4 2.8e-07 30.9 0.3 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KPI37714.1 - 4.7e-05 22.4 0.0 0.00028 19.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KPI37714.1 - 0.00016 21.4 3.7 0.15 11.7 0.0 3.4 1 1 2 3 3 3 2 Phosphotransferase enzyme family Microtub_assoc PF07989.6 KPI37715.1 - 0.27 11.1 5.3 13 5.6 1.8 2.5 2 0 0 2 2 2 0 Microtubule associated DUF972 PF06156.8 KPI37715.1 - 0.96 9.8 3.0 2.1 8.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF4094 PF13334.1 KPI37715.1 - 2.3 8.6 4.9 8.6 6.8 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) tRNA-synt_1c PF00749.16 KPI37716.1 - 5.3e-80 268.4 0.0 8e-80 267.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain HSDR_N PF04313.9 KPI37716.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Glyco_hydro_3 PF00933.16 KPI37717.1 - 5.8e-88 294.7 0.0 7.7e-88 294.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Amidase PF01425.16 KPI37718.1 - 8e-93 311.6 0.0 9.8e-93 311.3 0.0 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 KPI37719.1 - 7.5e-32 110.3 34.4 7.5e-32 110.3 23.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4190 PF13828.1 KPI37719.1 - 0.025 14.1 0.1 0.025 14.1 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4190) PDT PF00800.13 KPI37720.1 - 5.1e-29 101.0 0.1 4.4e-08 32.8 0.0 4.0 4 0 0 4 4 4 4 Prephenate dehydratase DUF4237 PF14021.1 KPI37720.1 - 0.018 15.3 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4237) Patatin PF01734.17 KPI37721.1 - 2e-10 40.9 0.0 3.9e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.17 KPI37722.1 - 1.8e-09 37.8 0.0 2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Patatin-like phospholipase Carb_anhydrase PF00194.16 KPI37723.1 - 2.8e-20 72.3 0.1 3e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Pilin PF00114.14 KPI37724.1 - 0.053 14.2 0.6 0.064 13.9 0.4 1.1 1 0 0 1 1 1 0 Pilin (bacterial filament) Stm1_N PF09598.5 KPI37724.1 - 0.4 11.4 4.5 0.49 11.1 3.1 1.2 1 0 0 1 1 1 0 Stm1 LEA_4 PF02987.11 KPI37725.1 - 2.9e-08 33.4 16.4 3.5e-06 26.7 0.7 2.5 1 1 0 2 2 2 2 Late embryogenesis abundant protein DUF883 PF05957.8 KPI37725.1 - 0.02 15.2 11.2 0.29 11.5 7.8 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 KPI37725.1 - 0.23 10.9 13.5 1 8.8 0.2 2.4 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain ATP-synt_B PF00430.13 KPI37725.1 - 4.5 7.0 14.6 9.7 6.0 9.2 1.8 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) LEA_1 PF03760.10 KPI37725.1 - 6.4 6.9 20.8 0.56 10.4 0.4 2.5 1 1 1 2 2 2 0 Late embryogenesis abundant (LEA) group 1 ADH_N PF08240.7 KPI37727.1 - 6.2e-19 67.7 0.7 1.3e-18 66.7 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI37727.1 - 1.6e-07 30.9 0.1 3.8e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KPI37727.1 - 0.0027 18.2 0.1 0.005 17.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI37727.1 - 0.023 14.7 0.9 0.053 13.5 0.6 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KPI37727.1 - 0.076 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SHMT PF00464.14 KPI37728.1 - 3.3e-197 654.6 0.0 3.8e-197 654.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase NAD_binding_6 PF08030.7 KPI37730.1 - 4.7e-19 68.8 0.0 7.9e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KPI37730.1 - 8.2e-18 64.2 0.0 2.1e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KPI37730.1 - 2e-11 44.0 12.2 2e-11 44.0 8.5 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component PDR_assoc PF08370.6 KPI37730.1 - 0.015 14.7 0.1 0.015 14.7 0.1 2.3 3 0 0 3 3 3 0 Plant PDR ABC transporter associated FAD_binding_6 PF00970.19 KPI37730.1 - 0.02 15.0 0.0 0.068 13.2 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain Fungal_trans PF04082.13 KPI37731.1 - 2.1e-19 69.4 0.1 4.2e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_1 PF00515.23 KPI37731.1 - 0.19 11.4 0.1 5 6.9 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Herpes_V23 PF01802.12 KPI37732.1 - 0.037 13.0 0.1 0.046 12.7 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein ADH_N PF08240.7 KPI37733.1 - 8.7e-17 60.8 5.2 1.9e-16 59.7 3.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI37733.1 - 1.1e-06 28.2 0.0 3.8e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KPI37733.1 - 0.011 14.8 0.1 0.018 14.2 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1640 PF07798.6 KPI37734.1 - 1.2e-08 35.2 6.6 1.2e-08 35.2 4.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) DUF3767 PF12597.3 KPI37734.1 - 0.058 13.0 1.1 0.13 11.9 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) Sds3 PF08598.6 KPI37734.1 - 0.17 11.4 15.7 0.019 14.4 7.8 1.6 2 0 0 2 2 2 0 Sds3-like HET PF06985.6 KPI37735.1 - 1.4e-20 73.8 0.6 3e-20 72.7 0.4 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 KPI37735.1 - 1.4e-09 38.1 0.1 5.2e-09 36.2 0.1 2.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI37735.1 - 0.00034 20.3 0.0 0.00077 19.1 0.0 1.6 1 0 0 1 1 1 1 KR domain Sugar_tr PF00083.19 KPI37736.1 - 4e-26 91.6 25.8 5.6e-23 81.2 8.8 3.1 2 1 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 KPI37736.1 - 1.5e-24 86.3 27.2 4.8e-24 84.7 18.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily PIRT PF15099.1 KPI37736.1 - 0.0079 15.4 0.0 0.022 13.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family KilA-N PF04383.8 KPI37737.1 - 0.00011 21.7 0.0 0.0014 18.1 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain Ferritin_2 PF13668.1 KPI37739.1 - 4.9e-17 62.1 0.2 7.5e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain BTB PF00651.26 KPI37740.1 - 0.00028 20.8 0.0 0.00047 20.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain eRF1_2 PF03464.10 KPI37741.1 - 7.4e-47 159.0 0.1 1.4e-46 158.1 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KPI37741.1 - 2.5e-37 127.5 0.1 6.2e-37 126.3 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KPI37741.1 - 1.4e-28 99.1 0.1 2.4e-28 98.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 DUF1338 PF07063.8 KPI37742.1 - 1.4e-76 257.4 0.0 1.7e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Myosin_head PF00063.16 KPI37744.1 - 1.1e-244 813.6 0.0 1.1e-244 813.6 0.0 2.2 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.14 KPI37744.1 - 3.1e-07 29.9 3.3 3.1e-07 29.9 0.9 2.1 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 KPI37744.1 - 0.058 13.1 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KPI37744.1 - 0.062 13.4 0.0 0.062 13.4 0.0 3.8 4 2 1 5 5 5 0 AAA domain Filament PF00038.16 KPI37744.1 - 5.3 6.4 89.2 8.7 5.7 18.3 2.9 1 1 1 2 2 2 0 Intermediate filament protein SET PF00856.23 KPI37745.1 - 1.1e-12 48.5 0.1 5.2e-12 46.3 0.0 2.0 1 1 0 1 1 1 1 SET domain Tho2 PF11262.3 KPI37746.1 - 3.6e-71 239.6 0.0 6e-71 238.9 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KPI37746.1 - 4.6e-24 84.0 0.0 1e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Sel1 PF08238.7 KPI37748.1 - 3.9e-43 144.9 33.7 2.6e-07 31.0 0.0 7.7 7 0 0 7 7 7 7 Sel1 repeat SecY PF00344.15 KPI37749.1 - 8.6e-94 314.2 7.3 1.1e-93 313.9 5.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KPI37749.1 - 3.6e-18 64.7 0.3 1.1e-17 63.2 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p ThiF PF00899.16 KPI37750.1 - 5.1e-17 61.9 0.0 9.9e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 ThiF family F-box PF00646.28 KPI37751.1 - 1e-05 25.0 0.4 0.00037 20.0 0.2 3.2 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 KPI37751.1 - 0.00026 20.6 1.1 0.00076 19.1 0.2 2.3 2 0 0 2 2 2 1 F-box-like Zn_clus PF00172.13 KPI37752.1 - 0.00072 19.4 0.5 0.0015 18.3 0.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOR_SNZ PF01680.12 KPI37753.1 - 1.4e-85 286.1 5.3 1e-84 283.3 3.7 2.1 1 1 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 KPI37753.1 - 6.1e-06 25.4 0.2 6.1e-06 25.4 0.1 2.3 2 1 1 3 3 3 1 Thiazole biosynthesis protein ThiG IGPS PF00218.16 KPI37753.1 - 0.0011 18.0 0.1 0.0024 17.0 0.0 1.5 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NMO PF03060.10 KPI37753.1 - 0.0033 16.6 3.2 0.0033 16.6 2.3 1.6 2 0 0 2 2 2 1 Nitronate monooxygenase Dus PF01207.12 KPI37753.1 - 0.0062 15.3 0.2 0.064 12.0 0.0 2.3 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) NanE PF04131.9 KPI37753.1 - 0.0068 15.4 0.3 0.025 13.5 0.0 2.0 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase MiaE_2 PF13794.1 KPI37753.1 - 0.027 13.9 0.2 0.11 11.9 0.0 2.0 2 1 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like His_biosynth PF00977.16 KPI37753.1 - 0.027 13.7 0.0 0.11 11.7 0.0 1.9 1 1 0 1 1 1 0 Histidine biosynthesis protein Trp_syntA PF00290.15 KPI37753.1 - 0.066 11.7 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain HA2 PF04408.18 KPI37754.1 - 2.8e-16 59.4 0.0 7e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 KPI37754.1 - 2e-13 50.1 0.1 5.2e-13 48.8 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI37754.1 - 2.4e-10 40.1 0.1 6e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_RecD PF05127.9 KPI37754.1 - 7.6e-05 22.4 0.0 0.00089 18.9 0.0 2.5 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.1 KPI37754.1 - 9.9e-05 22.4 0.1 0.00044 20.4 0.1 2.1 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KPI37754.1 - 0.0092 15.4 0.0 0.025 14.0 0.0 1.8 1 0 0 1 1 1 1 AAA-like domain Glycos_transf_2 PF00535.21 KPI37755.1 - 2e-20 73.1 0.0 1.7e-18 66.8 0.0 2.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KPI37755.1 - 2.7e-05 24.0 0.1 0.097 12.4 0.0 2.7 2 2 1 3 3 3 2 Glycosyltransferase like family 2 2OG-FeII_Oxy_2 PF13532.1 KPI37756.1 - 2.3e-34 118.9 0.0 1.3e-33 116.4 0.0 1.8 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily HCaRG PF07258.9 KPI37757.1 - 0.019 14.4 1.6 2.5 7.6 0.0 3.2 3 0 0 3 3 3 0 HCaRG protein MFS_1 PF07690.11 KPI37759.1 - 9.4e-28 96.9 21.1 2.1e-27 95.7 14.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI37759.1 - 1.6e-05 23.7 9.2 1.8e-05 23.5 1.8 2.5 1 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 KPI37759.1 - 0.0004 18.7 7.9 0.0005 18.4 5.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AAA_29 PF13555.1 KPI37759.1 - 0.16 11.4 2.5 7 6.2 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ribosomal_L17 PF01196.14 KPI37760.1 - 2.2e-31 108.2 0.0 3.4e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Myotub-related PF06602.9 KPI37760.1 - 0.37 9.5 1.6 7.2 5.2 0.0 2.0 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain PspA_IM30 PF04012.7 KPI37761.1 - 0.0026 17.1 0.0 0.0037 16.6 0.0 1.1 1 0 0 1 1 1 1 PspA/IM30 family DUF2841 PF11001.3 KPI37762.1 - 6.6e-30 103.5 2.5 1.3e-29 102.5 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Ctr PF04145.10 KPI37763.1 - 4.7e-32 111.0 0.3 5.5e-32 110.8 0.2 1.0 1 0 0 1 1 1 1 Ctr copper transporter family DUF2583 PF10762.4 KPI37763.1 - 0.02 15.0 2.4 0.023 14.8 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Peptidase_M41 PF01434.13 KPI37764.1 - 1e-76 257.1 0.1 1.9e-76 256.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KPI37764.1 - 4.8e-43 146.5 0.0 1.6e-42 144.8 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KPI37764.1 - 2e-10 40.7 0.0 4.9e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 KPI37764.1 - 5.9e-05 22.8 0.0 0.00019 21.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KPI37764.1 - 0.0014 18.7 0.9 0.23 11.5 0.1 3.1 4 0 0 4 4 4 1 AAA domain AAA_17 PF13207.1 KPI37764.1 - 0.0035 18.1 0.4 0.023 15.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 KPI37764.1 - 0.0059 15.6 0.1 0.045 12.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KPI37764.1 - 0.0071 15.0 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 KPI37764.1 - 0.0081 15.8 0.8 0.026 14.2 0.5 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KPI37764.1 - 0.021 14.8 0.9 0.22 11.4 0.1 2.7 2 1 0 3 3 3 0 AAA ATPase domain AAA_14 PF13173.1 KPI37764.1 - 0.024 14.5 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KPI37764.1 - 0.074 12.4 2.5 0.33 10.3 0.3 2.5 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KPI37764.1 - 0.091 12.1 0.7 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 KPI37764.1 - 0.092 11.8 0.7 0.25 10.4 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin DUF1744 PF08490.7 KPI37765.1 - 0.058 11.9 0.0 0.068 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) MFS_1 PF07690.11 KPI37765.1 - 1 8.0 9.1 0.06 12.0 2.8 1.4 2 0 0 2 2 2 0 Major Facilitator Superfamily 4HBT_3 PF13622.1 KPI37766.1 - 5.1e-32 111.6 1.6 6.9e-32 111.1 1.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KPI37766.1 - 1.3e-08 34.5 0.1 1e-06 28.3 0.1 2.9 2 2 0 2 2 2 1 Acyl-CoA thioesterase PS-DH PF14765.1 KPI37766.1 - 0.00086 18.5 0.2 0.019 14.1 0.0 2.7 2 2 1 3 3 3 1 Polyketide synthase dehydratase AfsA PF03756.8 KPI37766.1 - 0.0095 15.6 0.1 0.036 13.8 0.0 1.8 2 0 0 2 2 2 1 A-factor biosynthesis hotdog domain Rap_GAP PF02145.10 KPI37767.1 - 1.6e-41 141.7 0.0 2.7e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 KPI37767.1 - 7.2e-21 74.6 3.4 8.9e-20 71.0 0.3 2.8 3 0 0 3 3 3 2 Tuberin DUF3384 PF11864.3 KPI37767.1 - 4.6e-06 25.3 0.5 5e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Chitin_synth_1 PF01644.12 KPI37768.1 - 1.7e-46 158.0 0.0 2.9e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KPI37768.1 - 1.5e-22 79.7 0.2 3.4e-21 75.2 0.1 2.5 1 1 1 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.6 KPI37768.1 - 8.4e-06 25.3 0.0 1.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal DUF2247 PF10004.4 KPI37768.1 - 0.034 13.8 0.1 0.25 11.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) LigB PF02900.13 KPI37769.1 - 1.3e-48 165.3 0.0 1.5e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase NUDIX PF00293.23 KPI37770.1 - 5.2e-15 55.2 0.1 2.3e-14 53.1 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain Zn_clus PF00172.13 KPI37771.1 - 1.5e-09 37.6 9.8 1.5e-09 37.6 6.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 KPI37772.1 - 3.6e-71 239.7 0.0 4.2e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI37772.1 - 3.3e-13 50.3 0.0 6.4e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HpcH_HpaI PF03328.9 KPI37773.1 - 1.1e-30 106.1 1.0 1.5e-30 105.7 0.7 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.13 KPI37773.1 - 0.00012 21.1 0.2 0.00032 19.6 0.2 1.7 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain Peroxin-3 PF04882.7 KPI37774.1 - 3.8e-107 358.6 0.0 4.6e-107 358.4 0.0 1.1 1 0 0 1 1 1 1 Peroxin-3 DUF4043 PF13252.1 KPI37774.1 - 0.035 13.0 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) ABC_membrane PF00664.18 KPI37775.1 - 4.8e-76 255.7 26.1 5.8e-41 140.7 4.6 2.6 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KPI37775.1 - 1e-51 174.8 0.1 1.3e-29 103.2 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KPI37775.1 - 8.7e-10 38.1 9.0 0.0011 18.2 0.1 4.4 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KPI37775.1 - 4.4e-06 26.8 5.7 0.027 14.4 0.0 3.5 4 0 0 4 4 4 2 AAA ATPase domain AAA_21 PF13304.1 KPI37775.1 - 5.6e-06 26.5 0.1 0.23 11.3 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 KPI37775.1 - 2.4e-05 24.7 0.0 0.0015 18.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KPI37775.1 - 5.7e-05 22.5 0.9 0.1 12.1 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KPI37775.1 - 7.2e-05 22.7 0.0 0.43 10.5 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 KPI37775.1 - 0.00019 20.9 0.0 0.11 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KPI37775.1 - 0.00057 19.1 0.6 0.18 10.9 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function, DUF258 Miro PF08477.8 KPI37775.1 - 0.0038 17.7 0.3 3.1 8.3 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein DUF87 PF01935.12 KPI37775.1 - 0.0064 16.3 2.2 1.1 9.0 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 Dynamin_N PF00350.18 KPI37775.1 - 0.0067 16.2 3.3 1.4 8.6 0.0 3.8 3 0 0 3 3 3 1 Dynamin family T2SE PF00437.15 KPI37775.1 - 0.025 13.4 0.1 0.82 8.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_17 PF13207.1 KPI37775.1 - 0.059 14.1 0.0 15 6.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain CDC45 PF02724.9 KPI37775.1 - 0.074 11.0 0.1 0.12 10.4 0.0 1.2 1 0 0 1 1 1 0 CDC45-like protein AAA_10 PF12846.2 KPI37775.1 - 0.097 12.0 3.2 0.91 8.8 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 KPI37775.1 - 0.13 12.4 0.0 4.8 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_PrkA PF08298.6 KPI37775.1 - 0.13 10.9 0.0 3.3 6.3 0.0 2.8 3 0 0 3 3 3 0 PrkA AAA domain AAA_22 PF13401.1 KPI37775.1 - 0.14 12.2 2.9 11 6.1 0.0 4.1 4 1 0 4 4 3 0 AAA domain DUF3381 PF11861.3 KPI37775.1 - 0.16 11.5 0.4 0.31 10.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) FtsK_SpoIIIE PF01580.13 KPI37775.1 - 0.3 10.5 2.8 2 7.8 0.0 2.6 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_15 PF13175.1 KPI37775.1 - 0.41 9.6 0.0 0.78 8.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AIG1 PF04548.11 KPI37775.1 - 6.1 5.8 5.9 5.5 6.0 0.1 2.8 3 0 0 3 3 2 0 AIG1 family DUF619 PF04768.8 KPI37776.1 - 3.1e-43 147.1 0.4 1.2e-41 142.0 0.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 KPI37776.1 - 2.1e-31 108.7 0.0 6.1e-31 107.2 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 KPI37776.1 - 5.7e-22 78.4 0.0 1.2e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 KPI37776.1 - 0.0092 15.8 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Arm PF00514.18 KPI37776.1 - 0.086 12.6 0.2 1 9.2 0.0 2.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat D123 PF07065.9 KPI37777.1 - 5.8e-92 307.9 0.0 6.9e-92 307.7 0.0 1.0 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 KPI37777.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4343) DUF3554 PF12074.3 KPI37778.1 - 2.2e-52 178.6 3.3 6.9e-52 176.9 0.0 3.6 3 1 1 4 4 4 1 Domain of unknown function (DUF3554) HEAT PF02985.17 KPI37778.1 - 2.1e-30 102.0 50.0 0.025 14.6 0.0 24.0 28 0 0 28 28 27 7 HEAT repeat HEAT_2 PF13646.1 KPI37778.1 - 1e-27 96.1 76.0 1e-10 41.7 0.1 18.2 11 4 9 21 21 21 8 HEAT repeats HEAT_EZ PF13513.1 KPI37778.1 - 9.9e-22 76.8 61.8 1.1e-05 25.7 0.0 21.0 18 6 8 26 26 24 6 HEAT-like repeat Cnd1 PF12717.2 KPI37778.1 - 3.7e-17 62.7 0.0 0.48 10.2 0.0 10.1 5 1 4 11 11 11 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KPI37778.1 - 3.2e-14 53.0 0.0 0.13 12.6 0.0 9.5 7 3 3 10 10 10 4 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KPI37778.1 - 1.7e-10 40.6 0.0 0.2 10.9 0.0 7.7 5 2 1 6 6 6 2 CLASP N terminal ParcG PF10274.4 KPI37778.1 - 1.2e-09 38.3 4.4 0.0078 16.1 0.0 7.2 8 2 1 9 9 9 2 Parkin co-regulated protein Ipi1_N PF12333.3 KPI37778.1 - 7.4e-07 29.0 7.7 0.095 12.6 0.0 7.4 8 0 0 8 8 8 1 Rix1 complex component involved in 60S ribosome maturation Adaptin_N PF01602.15 KPI37778.1 - 0.00068 18.0 12.2 4.5 5.4 0.3 7.3 4 2 0 4 4 4 1 Adaptin N terminal region Cohesin_HEAT PF12765.2 KPI37778.1 - 0.025 14.5 6.8 0.1 12.6 0.0 5.5 6 0 0 6 6 5 0 HEAT repeat associated with sister chromatid cohesion Arm PF00514.18 KPI37778.1 - 0.031 14.1 12.3 36 4.3 0.0 7.6 7 1 0 7 7 7 0 Armadillo/beta-catenin-like repeat NAGLU_C PF12972.2 KPI37778.1 - 0.26 10.6 0.1 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain WSC PF01822.14 KPI37779.1 - 9.6e-54 179.2 60.0 2.3e-18 65.8 8.8 4.0 4 0 0 4 4 4 3 WSC domain PAN_4 PF14295.1 KPI37779.1 - 0.0046 16.6 3.3 0.0046 16.6 2.3 6.8 8 0 0 8 8 8 1 PAN domain zf-Di19 PF05605.7 KPI37781.1 - 0.0087 16.1 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding LLC1 PF14945.1 KPI37781.1 - 0.024 14.9 1.3 0.024 14.9 0.9 2.1 3 0 0 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein zf-C2HC_2 PF13913.1 KPI37781.1 - 0.042 13.5 0.3 0.08 12.6 0.2 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.1 KPI37781.1 - 0.13 12.6 0.2 0.51 10.8 0.1 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Glyoxalase PF00903.20 KPI37782.1 - 1e-11 44.8 0.0 1.5e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KPI37782.1 - 6e-08 33.2 0.0 1.1e-07 32.4 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain CAS_CSE1 PF03378.10 KPI37783.1 - 1.3e-155 518.0 0.1 1.6e-154 514.3 0.0 2.5 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KPI37783.1 - 1.2e-140 468.2 1.5 2e-140 467.5 1.0 1.4 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 KPI37783.1 - 2e-13 50.0 0.1 1.8e-12 46.9 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain V-ATPase_H_N PF03224.9 KPI37783.1 - 0.018 14.1 0.0 0.14 11.2 0.0 2.4 2 1 1 3 3 3 0 V-ATPase subunit H Xpo1 PF08389.7 KPI37783.1 - 0.05 13.5 3.6 0.082 12.8 0.0 3.4 3 1 0 3 3 3 0 Exportin 1-like protein DUF3632 PF12311.3 KPI37784.1 - 1.7e-16 60.5 0.2 7e-16 58.5 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) NAD_binding_4 PF07993.7 KPI37785.1 - 2.7e-35 121.5 0.0 4e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KPI37785.1 - 6.1e-28 97.3 0.0 1.5e-27 96.0 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 KPI37785.1 - 6.5e-11 42.1 0.0 1.5e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KPI37785.1 - 7.9e-05 22.3 0.0 0.00028 20.6 0.0 1.9 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 KPI37785.1 - 0.00011 22.1 0.2 0.00053 19.9 0.2 2.2 1 1 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 KPI37785.1 - 0.0023 18.1 0.1 0.0053 17.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 KPI37785.1 - 0.011 15.7 0.0 0.06 13.3 0.0 2.3 2 1 0 2 2 2 0 NADH(P)-binding BTB PF00651.26 KPI37787.1 - 1.1e-05 25.3 0.1 0.00072 19.5 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain DUF229 PF02995.12 KPI37787.1 - 0.17 10.2 0.1 0.26 9.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Zn_clus PF00172.13 KPI37788.1 - 4.8e-07 29.5 12.8 7.9e-07 28.8 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRCT PF00533.21 KPI37788.1 - 3.1e-05 24.0 0.0 6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Fungal_trans PF04082.13 KPI37788.1 - 0.00023 20.1 0.6 0.00051 18.9 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain PTCB-BRCT PF12738.2 KPI37788.1 - 0.028 14.2 0.1 0.13 12.0 0.1 2.2 2 0 0 2 2 2 0 twin BRCT domain HATPase_c PF02518.21 KPI37789.1 - 3e-22 78.4 0.1 6.2e-22 77.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KPI37789.1 - 1.9e-17 63.2 0.0 5.9e-17 61.6 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KPI37789.1 - 3.6e-13 49.2 0.0 8.9e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.1 KPI37789.1 - 0.037 13.8 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 KPI37789.1 - 0.044 13.4 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.1 KPI37789.1 - 0.14 11.8 0.0 0.52 10.0 0.0 2.0 1 0 0 1 1 1 0 GHKL domain adh_short PF00106.20 KPI37790.1 - 3.8e-26 91.9 4.5 5e-26 91.5 3.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI37790.1 - 5.2e-20 72.2 0.3 6.3e-20 71.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI37790.1 - 1.5e-08 34.5 2.7 2.1e-08 34.0 1.9 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI37790.1 - 3.1e-05 23.5 1.0 5.5e-05 22.7 0.7 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KPI37790.1 - 5.9e-05 22.7 0.4 0.00012 21.7 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KPI37790.1 - 0.001 19.0 2.1 0.0026 17.7 1.4 1.6 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KPI37790.1 - 0.0017 17.4 0.2 0.004 16.2 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UDPG_MGDP_dh_N PF03721.9 KPI37790.1 - 0.0021 17.4 0.2 0.0035 16.7 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Polysacc_synt_2 PF02719.10 KPI37790.1 - 0.0022 16.9 0.2 0.0033 16.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KPI37790.1 - 0.0046 15.6 1.9 0.032 12.9 1.1 2.0 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 KPI37790.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 KPI37790.1 - 0.19 11.5 3.0 0.55 10.0 0.4 2.8 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ldh_1_N PF00056.18 KPI37790.1 - 0.22 11.3 1.8 0.36 10.6 1.0 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ArfGap PF01412.13 KPI37791.1 - 2e-30 104.9 0.2 2e-30 104.9 0.1 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf MPC PF03650.8 KPI37792.1 - 4.6e-41 139.5 0.1 6.4e-41 139.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MtN3_slv PF03083.11 KPI37792.1 - 0.066 13.0 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange TauD PF02668.11 KPI37793.1 - 2.7e-43 148.5 1.1 3.2e-43 148.2 0.8 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family BTB PF00651.26 KPI37796.1 - 0.0082 16.1 0.0 0.017 15.1 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain RFX_DNA_binding PF02257.10 KPI37797.1 - 4e-28 97.3 0.2 1.8e-27 95.3 0.0 2.2 2 0 0 2 2 2 1 RFX DNA-binding domain ArgJ PF01960.13 KPI37798.1 - 3.4e-144 480.0 1.2 3.9e-144 479.8 0.8 1.0 1 0 0 1 1 1 1 ArgJ family p450 PF00067.17 KPI37800.1 - 2.1e-66 224.3 0.0 2.6e-41 141.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 FAD_binding_1 PF00667.15 KPI37800.1 - 2.7e-33 115.2 0.1 4.1e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KPI37800.1 - 3.7e-17 62.6 0.0 8.1e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KPI37800.1 - 3.2e-14 53.4 0.0 9.4e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KPI37800.1 - 0.00041 20.4 0.1 0.021 14.9 0.0 3.0 2 1 1 3 3 3 1 Oxidoreductase FAD-binding domain SBP_bac_5 PF00496.17 KPI37800.1 - 0.0058 15.5 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Flavodoxin_5 PF12724.2 KPI37800.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain Synaptobrevin PF00957.16 KPI37801.1 - 1.6e-12 46.8 2.5 2e-12 46.5 1.7 1.1 1 0 0 1 1 1 1 Synaptobrevin DUF1035 PF06281.7 KPI37801.1 - 0.12 12.2 3.0 0.19 11.5 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) Glyco_hydro_3_C PF01915.17 KPI37802.1 - 1.1e-48 165.7 0.0 1.9e-48 164.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KPI37802.1 - 2.4e-17 62.6 0.4 6.2e-17 61.3 0.3 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KPI37802.1 - 4.7e-10 39.2 0.0 1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 PA14 domain CARDB PF07705.6 KPI37802.1 - 0.00048 20.1 0.8 0.028 14.4 0.0 3.1 3 1 1 4 4 4 1 CARDB BTB PF00651.26 KPI37803.1 - 0.0014 18.5 0.0 0.0037 17.2 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KPI37804.1 - 0.00014 21.8 0.3 0.45 10.5 0.0 2.2 2 0 0 2 2 2 2 BTB/POZ domain Cu-oxidase_2 PF07731.9 KPI37805.1 - 9.6e-43 145.0 0.5 9.6e-43 145.0 0.3 2.8 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KPI37805.1 - 7.6e-27 93.3 0.5 7.6e-27 93.3 0.3 3.2 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 KPI37805.1 - 9.8e-24 84.0 0.1 6e-23 81.4 0.1 2.1 2 0 0 2 2 2 1 Multicopper oxidase Glyco_hydro_10 PF00331.15 KPI37806.1 - 6e-91 304.7 0.0 6.9e-91 304.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Erf4 PF10256.4 KPI37807.1 - 1.3e-05 25.0 0.0 5.1e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family DUF4646 PF15496.1 KPI37807.1 - 0.0091 16.0 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) DUF3584 PF12128.3 KPI37807.1 - 0.023 12.0 10.9 0.031 11.6 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Methyltransf_23 PF13489.1 KPI37808.1 - 1.3e-13 51.0 0.0 1.8e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI37808.1 - 3.1e-07 30.7 0.0 4.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI37808.1 - 4.1e-05 23.9 0.0 6.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI37808.1 - 0.0057 17.2 0.0 0.0083 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI37808.1 - 0.0072 15.9 0.0 0.025 14.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI37808.1 - 0.019 15.3 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KPI37808.1 - 0.03 14.3 0.0 0.061 13.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF605 PF04652.11 KPI37809.1 - 0.52 9.6 13.2 0.59 9.4 9.2 1.0 1 0 0 1 1 1 0 Vta1 like Pneumo_att_G PF05539.6 KPI37809.1 - 0.71 9.1 16.0 0.85 8.9 11.1 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Med13_C PF06333.7 KPI37809.1 - 3.5 6.0 9.0 4.3 5.7 6.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Gln-synt_C PF00120.19 KPI37810.1 - 9.6e-62 208.4 0.0 1.2e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain TB2_DP1_HVA22 PF03134.14 KPI37811.1 - 2e-29 101.1 7.4 2.7e-29 100.7 5.1 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Zn_clus PF00172.13 KPI37813.1 - 2e-06 27.6 8.9 2e-06 27.6 6.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KPI37813.1 - 0.054 12.0 0.1 0.082 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Init_tRNA_PT PF04179.7 KPI37814.1 - 9.2e-115 384.0 0.0 2.8e-114 382.4 0.0 1.6 1 1 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Sugar_tr PF00083.19 KPI37815.1 - 4.1e-17 61.8 26.7 1e-09 37.5 9.6 3.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI37815.1 - 3.4e-16 58.9 30.4 2.8e-12 46.0 5.8 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Saccharop_dh PF03435.13 KPI37816.1 - 9.1e-129 429.7 0.0 1.1e-128 429.4 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KPI37816.1 - 4.3e-07 30.1 0.1 6.6e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KPI37816.1 - 1.1e-05 25.5 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 KPI37816.1 - 0.00082 19.7 0.1 0.002 18.5 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 KPI37816.1 - 0.016 15.4 0.1 0.038 14.2 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_3 PF03447.11 KPI37816.1 - 0.03 14.7 0.1 0.055 13.8 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain IlvN PF07991.7 KPI37816.1 - 0.034 13.5 0.1 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Fungal_trans PF04082.13 KPI37818.1 - 2.7e-19 69.0 0.1 4.5e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI37818.1 - 2.6e-08 33.6 8.0 5.8e-08 32.5 5.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KPI37820.1 - 1.1e-25 89.9 0.6 1.1e-25 89.9 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI37820.1 - 1.6e-05 24.6 9.1 3.6e-05 23.5 6.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L27 PF01016.14 KPI37821.1 - 5.1e-14 51.8 0.1 1.4e-13 50.3 0.1 1.8 1 0 0 1 1 1 1 Ribosomal L27 protein Y_phosphatase3 PF13350.1 KPI37822.1 - 1.4e-42 145.7 0.0 2.3e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KPI37822.1 - 1.8e-08 34.3 0.1 4.2e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 KPI37822.1 - 0.0012 18.2 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KPI37822.1 - 0.0028 17.0 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KPI37822.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Apc3 PF12895.2 KPI37824.1 - 4e-24 84.5 13.7 7.3e-19 67.6 0.2 5.6 4 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KPI37824.1 - 9.7e-23 79.6 18.0 4e-07 29.5 0.2 7.8 6 2 1 7 7 7 6 TPR repeat TPR_2 PF07719.12 KPI37824.1 - 9.3e-22 75.1 14.9 0.0017 18.1 0.2 8.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.23 KPI37824.1 - 2.5e-21 74.3 5.2 0.0011 18.4 0.2 9.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 KPI37824.1 - 2.2e-18 65.9 18.6 7.7e-09 35.3 0.2 7.6 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 KPI37824.1 - 4.6e-14 52.5 4.9 0.02 15.2 0.0 5.9 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 KPI37824.1 - 2.4e-12 46.3 12.3 0.13 12.9 0.1 9.5 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.1 KPI37824.1 - 8.1e-12 44.0 0.2 0.22 11.3 0.0 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 KPI37824.1 - 8.4e-11 42.2 17.0 0.0009 19.8 0.4 7.7 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 KPI37824.1 - 3.1e-08 33.2 17.4 0.0099 15.7 0.8 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 KPI37824.1 - 4.8e-06 25.9 19.9 1.2 9.1 0.0 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 KPI37824.1 - 6.8e-05 22.7 0.7 2.5 8.5 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 KPI37824.1 - 0.0017 18.7 11.9 4.3 8.0 0.1 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat Mannosyl_trans2 PF04188.8 KPI37825.1 - 2.8e-55 188.0 13.9 2.3e-53 181.6 9.6 2.4 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) Pro_CA PF00484.14 KPI37826.1 - 7e-38 130.0 0.0 8.6e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase MMgT PF10270.4 KPI37827.1 - 1.2e-21 77.1 0.0 1.4e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter ADH_zinc_N PF00107.21 KPI37828.1 - 2.4e-05 23.9 0.0 4.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4066 PF13278.1 KPI37830.1 - 1.4e-18 66.6 0.0 1.8e-16 59.8 0.0 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 KPI37830.1 - 0.058 12.8 0.4 7.9 5.9 0.0 2.9 2 2 0 2 2 2 0 DJ-1/PfpI family Nitroreductase PF00881.19 KPI37832.1 - 7e-13 48.7 0.0 8.4e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Pyridox_oxidase PF01243.15 KPI37833.1 - 3.9e-06 26.7 0.0 6.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase V_ATPase_I PF01496.14 KPI37834.1 - 3.8e-298 990.6 1.0 4.3e-298 990.4 0.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.16 KPI37834.1 - 0.0052 16.2 5.2 0.88 8.9 0.1 2.2 2 0 0 2 2 2 2 Intermediate filament protein CheZ PF04344.8 KPI37834.1 - 0.034 13.8 1.1 0.16 11.6 0.1 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Serine_rich PF08824.5 KPI37834.1 - 0.059 13.0 0.3 0.059 13.0 0.2 1.8 2 0 0 2 2 2 0 Serine rich protein interaction domain Baculo_PEP_C PF04513.7 KPI37834.1 - 0.11 12.3 1.5 0.51 10.1 0.2 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.15 KPI37834.1 - 1 9.1 4.1 4.4 7.1 0.7 2.9 3 0 0 3 3 3 0 Prefoldin subunit PRELI PF04707.9 KPI37835.1 - 4.3e-41 140.1 0.1 5.1e-41 139.8 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family ACOX PF01756.14 KPI37836.1 - 2.2e-37 128.2 0.1 8.2e-37 126.3 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KPI37836.1 - 9.5e-30 103.4 0.4 2e-29 102.3 0.3 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KPI37836.1 - 6.1e-11 41.6 1.6 1.1e-10 40.8 0.5 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KPI37836.1 - 5.7e-06 26.5 0.0 0.0032 17.5 0.0 2.6 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain GUCT PF08152.7 KPI37836.1 - 0.00056 19.8 0.1 0.002 18.0 0.0 1.9 2 0 0 2 2 2 1 GUCT (NUC152) domain ESCRT-II PF05871.7 KPI37836.1 - 0.056 13.3 0.2 0.49 10.3 0.3 2.3 2 1 0 2 2 2 0 ESCRT-II complex subunit Mito_carr PF00153.22 KPI37837.1 - 1.1e-44 150.0 0.3 2.2e-15 56.1 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.19 KPI37838.1 - 1.1e-64 218.7 22.8 1.3e-64 218.4 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI37838.1 - 7.9e-15 54.4 38.3 5e-12 45.1 10.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Filo_VP35 PF02097.10 KPI37840.1 - 0.018 14.2 0.0 0.15 11.2 0.0 2.0 2 0 0 2 2 2 0 Filoviridae VP35 Dna2 PF08696.6 KPI37843.1 - 1.4e-62 210.7 0.0 2.6e-62 209.8 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 KPI37843.1 - 3.3e-53 180.0 0.0 2.8e-52 177.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KPI37843.1 - 1.1e-39 136.4 0.5 2.9e-20 72.8 0.0 2.9 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 KPI37843.1 - 3e-17 62.8 0.0 1e-16 61.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KPI37843.1 - 1.3e-12 47.2 0.8 2e-11 43.4 0.1 2.9 2 0 0 2 2 2 1 Part of AAA domain Cas_Cas4 PF01930.12 KPI37843.1 - 5e-09 36.2 0.3 6.2e-08 32.7 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 KPI37843.1 - 3.8e-08 33.1 0.4 0.28 10.6 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase SRP54 PF00448.17 KPI37843.1 - 0.00021 20.7 0.0 0.00063 19.2 0.0 1.9 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UvrD-helicase PF00580.16 KPI37843.1 - 0.00045 19.6 0.1 0.0013 18.0 0.0 1.8 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain CbiA PF01656.18 KPI37843.1 - 0.00053 19.4 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 KPI37843.1 - 0.00097 18.8 0.1 0.0039 16.8 0.0 2.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Helicase_RecD PF05127.9 KPI37843.1 - 0.0014 18.2 0.0 0.0042 16.7 0.0 1.8 1 1 0 1 1 1 1 Helicase DUF2075 PF09848.4 KPI37843.1 - 0.0021 17.1 0.0 0.0044 16.0 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 KPI37843.1 - 0.0027 16.7 0.1 0.021 13.7 0.1 2.1 1 1 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.1 KPI37843.1 - 0.0043 17.0 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 KPI37843.1 - 0.0072 15.7 0.0 0.024 14.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KPI37843.1 - 0.016 15.3 0.2 0.28 11.3 0.0 3.2 3 1 0 3 3 2 0 AAA domain DUF87 PF01935.12 KPI37843.1 - 0.038 13.8 2.6 0.09 12.5 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 RuvB_N PF05496.7 KPI37843.1 - 0.073 12.1 0.1 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 KPI37843.1 - 0.074 12.7 0.2 0.28 10.8 0.1 2.0 1 0 0 1 1 1 0 NTPase UvrD_C_2 PF13538.1 KPI37843.1 - 0.079 13.0 0.0 0.3 11.2 0.0 2.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.24 KPI37843.1 - 0.096 12.8 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPP_enzyme_N PF02776.13 KPI37844.1 - 5.6e-38 130.1 0.1 1.7e-37 128.5 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KPI37844.1 - 1.3e-23 83.2 0.1 4.8e-23 81.4 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KPI37844.1 - 1.9e-18 66.5 0.0 3.3e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Peptidase_M18 PF02127.10 KPI37845.1 - 2e-119 398.9 0.0 1.7e-117 392.6 0.0 2.0 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KPI37845.1 - 0.0076 15.0 0.0 0.6 8.8 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase TOM13 PF08219.6 KPI37846.1 - 3.5e-27 93.9 0.0 4.4e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 UBA PF00627.26 KPI37847.1 - 6.8e-07 28.9 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Peptidase_M43 PF05572.8 KPI37848.1 - 5.8e-12 45.4 1.9 1.2e-10 41.1 1.3 2.4 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 KPI37848.1 - 1.5e-05 25.1 0.1 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KPI37848.1 - 3e-05 24.0 1.1 6e-05 23.0 0.8 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KPI37848.1 - 0.00015 22.3 0.1 0.00035 21.0 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KPI37848.1 - 0.0013 18.3 1.1 0.0023 17.4 0.8 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KPI37848.1 - 0.0022 17.7 0.0 0.0039 16.9 0.0 1.3 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 KPI37848.1 - 0.052 12.4 0.1 0.095 11.5 0.1 1.4 1 0 0 1 1 1 0 Peptidase M66 MFS_1 PF07690.11 KPI37849.1 - 1.2e-24 86.7 62.3 2e-19 69.5 25.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 KPI37851.1 - 1.4e-08 34.6 0.1 3.3e-08 33.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KPI37851.1 - 4.9e-07 29.8 0.0 3.4e-05 23.9 0.0 2.3 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KPI37851.1 - 4.7e-06 26.6 0.0 1.9e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KPI37851.1 - 1.4e-05 24.7 0.0 2.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KPI37851.1 - 6.9e-05 22.7 0.0 0.0072 16.1 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 KPI37851.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 MOZ/SAS family Thiolase_C PF02803.13 KPI37852.1 - 1.3e-10 40.7 0.9 1.1e-09 37.8 0.1 2.6 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KPI37852.1 - 1e-07 31.5 0.0 1.3e-05 24.7 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KPI37852.1 - 9.9e-05 21.4 0.6 0.0016 17.5 0.0 2.7 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 KPI37852.1 - 0.00031 20.3 0.3 0.00082 18.9 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KPI37852.1 - 0.013 15.2 0.2 0.6 9.9 0.0 2.6 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.6 KPI37852.1 - 0.072 11.5 0.2 0.15 10.5 0.1 1.5 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) DUF3208 PF11482.3 KPI37852.1 - 0.15 12.2 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) Aldo_ket_red PF00248.16 KPI37854.1 - 7.7e-37 126.6 0.0 8.7e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Beta-lactamase PF00144.19 KPI37855.1 - 8.9e-35 120.2 2.4 1.6e-34 119.4 1.6 1.4 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KPI37855.1 - 1.5e-07 31.1 0.0 4.6e-06 26.4 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) CTP_transf_2 PF01467.21 KPI37856.1 - 2.9e-16 59.9 0.0 2e-12 47.4 0.0 2.8 2 1 0 2 2 2 2 Cytidylyltransferase TrkH PF02386.11 KPI37857.1 - 4.5e-120 400.4 12.0 2.4e-119 398.0 5.9 2.1 2 0 0 2 2 2 2 Cation transport protein adh_short PF00106.20 KPI37858.1 - 1.1e-22 80.6 1.2 4.7e-22 78.6 0.8 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI37858.1 - 1.9e-10 40.6 0.6 1.2e-09 38.0 0.4 1.9 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI37858.1 - 2.7e-07 30.6 0.0 4.1e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KPI37858.1 - 5e-05 22.8 0.1 6.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI37858.1 - 6.6e-05 22.9 0.3 0.00011 22.2 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KPI37858.1 - 0.11 12.3 0.5 0.18 11.6 0.4 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Meth_synt_2 PF01717.13 KPI37859.1 - 7.1e-16 58.0 0.0 9.5e-16 57.6 0.0 1.2 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KPI37859.1 - 5.2e-05 22.6 0.1 0.0019 17.5 0.0 2.7 2 1 1 3 3 3 1 Cobalamin-independent synthase, N-terminal domain adh_short PF00106.20 KPI37860.1 - 8.9e-18 64.7 0.0 2.4e-17 63.3 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KPI37860.1 - 6.3e-12 45.5 0.0 1.5e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI37860.1 - 0.00018 21.0 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KPI37860.1 - 0.038 12.9 0.1 0.075 11.9 0.0 1.4 1 1 0 1 1 1 0 Male sterility protein DUF2855 PF11017.3 KPI37861.1 - 2.8e-54 184.3 0.0 3.4e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Glutaredoxin PF00462.19 KPI37862.1 - 1e-16 60.6 0.0 1.5e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin SEP PF08059.8 KPI37863.1 - 5.8e-27 93.8 0.0 1.4e-26 92.5 0.0 1.7 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 KPI37863.1 - 5.7e-12 44.9 0.2 9.1e-12 44.3 0.2 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KPI37863.1 - 1.8e-10 40.7 0.0 3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain Abhydrolase_3 PF07859.8 KPI37865.1 - 8.7e-47 159.4 0.0 1.3e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KPI37865.1 - 1e-05 24.4 0.0 1.7e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.4 KPI37865.1 - 0.071 12.3 1.1 1.3 8.2 0.1 2.4 2 0 0 2 2 2 0 Esterase PHB depolymerase MFS_1 PF07690.11 KPI37866.1 - 7.9e-32 110.3 61.6 3.8e-24 85.0 28.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KPI37866.1 - 0.0017 18.0 0.3 0.036 13.8 0.0 2.5 2 0 0 2 2 2 1 MFS_1 like family Fe-ADH PF00465.14 KPI37867.1 - 7.2e-57 192.6 0.2 1.3e-53 181.9 0.2 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KPI37867.1 - 8.3e-05 22.0 0.3 0.022 14.0 0.0 2.8 2 1 1 3 3 3 2 Iron-containing alcohol dehydrogenase SIR2 PF02146.12 KPI37868.1 - 7e-36 123.6 0.0 8.8e-34 116.7 0.0 2.3 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 KPI37868.1 - 0.00014 21.6 0.2 0.24 11.1 0.0 3.1 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain Adap_comp_sub PF00928.16 KPI37869.1 - 8.7e-70 234.8 0.0 2.8e-67 226.6 0.0 2.1 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KPI37869.1 - 4e-09 36.3 0.2 6.7e-09 35.6 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DAO PF01266.19 KPI37872.1 - 2.4e-60 204.3 0.0 2.7e-60 204.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KPI37872.1 - 0.075 12.0 0.4 0.12 11.4 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI37872.1 - 0.28 11.0 1.8 2 8.2 1.3 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI37872.1 - 0.78 8.5 4.5 0.37 9.5 0.0 2.0 1 1 1 2 2 2 0 FAD binding domain Iso_dh PF00180.15 KPI37874.1 - 1.6e-98 329.9 0.0 1.9e-98 329.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.2 KPI37874.1 - 0.11 12.3 0.0 0.95 9.4 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif Nop52 PF05997.7 KPI37875.1 - 4.4e-29 101.4 0.1 7.2e-29 100.7 0.1 1.3 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Fungal_trans PF04082.13 KPI37876.1 - 1.1e-42 145.7 0.0 2.1e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI37876.1 - 5.4e-09 35.8 7.2 1e-08 34.9 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_16 PF00722.16 KPI37877.1 - 5.7e-05 22.4 0.0 0.00012 21.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF2070 PF09843.4 KPI37877.1 - 0.055 12.9 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF108 PF01958.13 KPI37878.1 - 0.022 14.9 0.1 0.066 13.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF108 Curlin_rpt PF07012.7 KPI37878.1 - 0.2 11.3 1.9 0.43 10.3 1.3 1.5 1 0 0 1 1 1 0 Curlin associated repeat Ribosomal_L40e PF01020.12 KPI37880.1 - 3.7e-31 106.4 11.0 5.1e-31 106.0 7.6 1.2 1 0 0 1 1 1 1 Ribosomal L40e family zf-CHY PF05495.7 KPI37880.1 - 0.096 12.8 3.2 0.12 12.5 2.2 1.1 1 0 0 1 1 1 0 CHY zinc finger Nol1_Nop2_Fmu PF01189.12 KPI37881.1 - 7.9e-94 314.1 0.0 1.6e-93 313.1 0.0 1.5 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 KPI37881.1 - 0.0012 18.8 0.0 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KPI37881.1 - 0.0024 17.8 0.0 0.0067 16.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KPI37881.1 - 0.0042 16.6 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 KPI37881.1 - 0.0057 16.2 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI37881.1 - 0.047 14.2 1.1 0.52 10.9 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain COesterase PF00135.23 KPI37883.1 - 1e-100 337.9 0.0 1.3e-100 337.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI37883.1 - 3.2e-05 23.6 0.0 0.00062 19.4 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pkinase PF00069.20 KPI37884.1 - 6.4e-67 225.4 0.0 1e-66 224.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI37884.1 - 2.7e-47 161.0 0.0 4.2e-47 160.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI37884.1 - 0.0017 17.4 0.0 0.0043 16.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Glyoxalase_2 PF12681.2 KPI37885.1 - 2.2e-07 31.4 0.1 5.2e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Fungal_trans PF04082.13 KPI37886.1 - 9e-13 47.6 1.0 1.4e-12 47.0 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain IMS PF00817.15 KPI37886.1 - 0.017 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 impB/mucB/samB family DUF819 PF05684.7 KPI37886.1 - 0.11 11.2 0.0 0.31 9.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF819) Glyco_hydro_2_N PF02837.13 KPI37887.1 - 4.7e-10 39.2 0.6 1e-09 38.1 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KPI37887.1 - 0.012 14.5 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain TfoX_C PF04994.8 KPI37887.1 - 0.034 14.0 0.0 0.094 12.6 0.0 1.7 2 0 0 2 2 2 0 TfoX C-terminal domain bZIP_1 PF00170.16 KPI37888.1 - 4.5e-09 36.1 13.5 1.7e-08 34.3 9.0 2.0 1 1 1 2 2 2 1 bZIP transcription factor ATG16 PF08614.6 KPI37888.1 - 9.9e-05 22.2 5.2 0.00013 21.8 3.6 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 KPI37888.1 - 0.00018 20.1 0.6 0.00022 19.8 0.4 1.1 1 0 0 1 1 1 1 AAA domain HALZ PF02183.13 KPI37888.1 - 0.00062 19.4 0.4 0.0014 18.3 0.1 1.6 1 1 0 1 1 1 1 Homeobox associated leucine zipper OEP PF02321.13 KPI37888.1 - 0.001 18.7 4.3 0.0013 18.3 3.0 1.2 1 0 0 1 1 1 1 Outer membrane efflux protein LXG PF04740.7 KPI37888.1 - 0.0014 18.5 2.9 0.0017 18.2 2.0 1.1 1 0 0 1 1 1 1 LXG domain of WXG superfamily TPR_MLP1_2 PF07926.7 KPI37888.1 - 0.002 17.8 8.8 0.0028 17.4 6.1 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF812 PF05667.6 KPI37888.1 - 0.0021 16.6 9.5 0.0027 16.3 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Lebercilin PF15619.1 KPI37888.1 - 0.0025 17.2 8.1 0.0031 16.9 5.6 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease bZIP_2 PF07716.10 KPI37888.1 - 0.003 17.3 23.5 0.015 15.0 10.8 2.4 1 1 1 2 2 2 2 Basic region leucine zipper DUF1978 PF09321.5 KPI37888.1 - 0.0051 16.2 5.0 0.0069 15.8 3.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1978) APG6 PF04111.7 KPI37888.1 - 0.0071 15.4 6.5 0.0089 15.1 4.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 bZIP_Maf PF03131.12 KPI37888.1 - 0.0074 16.5 17.3 0.012 15.8 12.0 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF2400 PF09674.5 KPI37888.1 - 0.0079 15.9 0.3 0.0099 15.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2400) DUF3450 PF11932.3 KPI37888.1 - 0.0082 15.4 11.2 0.015 14.5 7.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) FUSC PF04632.7 KPI37888.1 - 0.012 14.1 0.3 0.015 13.7 0.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family PilJ PF13675.1 KPI37888.1 - 0.013 15.7 7.3 0.11 12.8 4.1 2.4 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term HOOK PF05622.7 KPI37888.1 - 0.014 13.2 8.8 0.017 12.9 6.1 1.0 1 0 0 1 1 1 0 HOOK protein V_ATPase_I PF01496.14 KPI37888.1 - 0.017 12.9 5.3 0.021 12.7 3.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 KPI37888.1 - 0.018 14.5 4.9 0.018 14.5 3.4 2.3 1 1 1 2 2 2 0 Septum formation initiator Fib_alpha PF08702.5 KPI37888.1 - 0.019 15.0 12.6 0.029 14.4 8.8 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.3 KPI37888.1 - 0.02 14.6 7.2 0.024 14.4 4.3 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding EAP30 PF04157.11 KPI37888.1 - 0.024 13.8 7.0 0.033 13.3 4.8 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family Prefoldin PF02996.12 KPI37888.1 - 0.024 14.2 6.0 0.37 10.4 0.2 2.3 1 1 1 2 2 2 0 Prefoldin subunit IncA PF04156.9 KPI37888.1 - 0.026 14.1 9.6 0.035 13.6 6.7 1.2 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 KPI37888.1 - 0.029 12.7 6.5 0.036 12.4 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SOBP PF15279.1 KPI37888.1 - 0.03 14.7 5.5 0.035 14.4 3.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Hom_end_hint PF05203.11 KPI37888.1 - 0.046 13.4 1.9 0.054 13.2 1.3 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint AAA_23 PF13476.1 KPI37888.1 - 0.047 14.0 4.4 0.058 13.7 3.1 1.1 1 0 0 1 1 1 0 AAA domain DUF4613 PF15390.1 KPI37888.1 - 0.048 11.8 2.5 0.055 11.6 1.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF1664 PF07889.7 KPI37888.1 - 0.049 13.4 2.1 0.081 12.7 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) MbeD_MobD PF04899.7 KPI37888.1 - 0.06 13.2 9.7 0.14 12.1 6.7 1.7 1 1 0 1 1 1 0 MbeD/MobD like DUF3584 PF12128.3 KPI37888.1 - 0.06 10.6 8.8 0.073 10.3 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_II PF06009.7 KPI37888.1 - 0.066 12.9 3.4 0.067 12.9 1.3 1.5 1 1 0 1 1 1 0 Laminin Domain II SprA-related PF12118.3 KPI37888.1 - 0.067 12.5 8.3 0.073 12.3 5.8 1.1 1 0 0 1 1 1 0 SprA-related family DUF724 PF05266.9 KPI37888.1 - 0.069 12.7 7.7 0.094 12.3 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Ax_dynein_light PF10211.4 KPI37888.1 - 0.083 12.7 8.9 0.13 12.0 6.2 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain NPV_P10 PF05531.7 KPI37888.1 - 0.1 12.8 2.6 0.11 12.7 0.7 1.9 2 0 0 2 2 1 0 Nucleopolyhedrovirus P10 protein FliD_C PF07195.7 KPI37888.1 - 0.12 11.6 4.5 0.17 11.1 3.1 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus HemX PF04375.9 KPI37888.1 - 0.12 10.9 9.7 0.15 10.6 6.7 1.1 1 0 0 1 1 1 0 HemX TBPIP PF07106.8 KPI37888.1 - 0.15 11.5 8.3 0.1 12.1 4.3 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GST_C_3 PF14497.1 KPI37888.1 - 0.19 12.2 0.8 0.52 10.8 0.6 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Spc7 PF08317.6 KPI37888.1 - 0.19 10.3 8.1 0.25 9.9 5.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.4 KPI37888.1 - 0.2 11.8 8.5 1.2 9.3 2.9 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.1 KPI37888.1 - 0.23 11.4 15.5 0.71 9.8 10.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4175 PF13779.1 KPI37888.1 - 0.29 8.8 13.3 0.34 8.5 9.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TMPIT PF07851.8 KPI37888.1 - 0.3 10.1 6.4 0.4 9.7 4.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein RmuC PF02646.11 KPI37888.1 - 0.4 9.4 7.6 0.18 10.6 3.4 1.7 1 1 1 2 2 2 0 RmuC family Atg14 PF10186.4 KPI37888.1 - 0.43 9.4 10.2 0.65 8.8 7.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FadA PF09403.5 KPI37888.1 - 0.47 10.4 7.0 0.86 9.6 4.8 1.4 1 0 0 1 1 1 0 Adhesion protein FadA RGS-like PF09128.6 KPI37888.1 - 0.48 9.8 5.2 0.59 9.5 3.6 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain DUF4164 PF13747.1 KPI37888.1 - 0.62 10.2 9.0 1.7 8.8 6.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) CorA PF01544.13 KPI37888.1 - 0.64 9.0 3.5 0.85 8.5 2.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Bap31 PF05529.7 KPI37888.1 - 1.1 8.6 8.1 1.5 8.2 5.6 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF1843 PF08898.5 KPI37888.1 - 1.6 8.8 5.7 2 8.5 2.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) OmpH PF03938.9 KPI37888.1 - 1.6 8.6 13.6 2.2 8.2 9.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FlxA PF14282.1 KPI37888.1 - 2 8.3 24.1 1.2 9.0 14.1 2.0 1 1 1 2 2 2 0 FlxA-like protein Vps5 PF09325.5 KPI37888.1 - 3.4 6.8 12.8 4.1 6.5 7.4 1.8 1 1 1 2 2 2 0 Vps5 C terminal like DUF972 PF06156.8 KPI37888.1 - 3.4 8.0 7.1 1.7 9.0 2.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Phage_Gp23 PF10669.4 KPI37888.1 - 4.2 7.4 10.4 8.2 6.5 7.2 1.5 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF4337 PF14235.1 KPI37888.1 - 4.5 7.0 6.6 6.5 6.5 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4446 PF14584.1 KPI37888.1 - 4.7 7.0 7.2 6.6 6.5 4.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Mnd1 PF03962.10 KPI37888.1 - 6.3 6.4 14.5 0.76 9.4 1.4 1.7 1 1 1 2 2 2 0 Mnd1 family Mitofilin PF09731.4 KPI37888.1 - 7.6 5.0 13.4 9.9 4.6 9.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein U1snRNP70_N PF12220.3 KPI37888.1 - 9.3 6.6 12.2 1.2 9.5 5.1 1.9 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Fungal_trans PF04082.13 KPI37889.1 - 3.3e-12 45.8 1.3 5.8e-12 45.0 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI37889.1 - 1e-09 38.1 10.4 1.9e-09 37.2 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SCAN PF02023.12 KPI37889.1 - 0.099 12.1 1.6 0.11 11.9 0.2 1.7 2 0 0 2 2 2 0 SCAN domain Aminotran_3 PF00202.16 KPI37890.1 - 4.4e-97 324.9 0.0 5.5e-97 324.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Granulin PF00396.13 KPI37891.1 - 3.2 7.9 20.1 1.2 9.2 2.7 3.7 2 1 1 3 3 3 0 Granulin 60KD_IMP PF02096.15 KPI37892.1 - 4.4e-33 114.6 4.7 6.7e-33 114.0 3.2 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein NMT1_2 PF13379.1 KPI37893.1 - 0.00028 20.3 0.0 0.00036 20.0 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family Sulfate_transp PF00916.15 KPI37894.1 - 1.9e-36 125.5 7.5 1.1e-24 86.9 0.2 3.2 1 1 2 3 3 3 2 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KPI37894.1 - 7e-28 96.1 1.7 7e-28 96.1 1.2 2.2 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KPI37894.1 - 4.6e-06 26.0 0.0 8.1e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain YtpI PF14007.1 KPI37894.1 - 0.037 13.9 2.9 3.6 7.5 0.1 3.5 3 0 0 3 3 3 0 YtpI-like protein DNA_ligase_A_C PF04679.10 KPI37894.1 - 0.14 12.5 0.0 0.53 10.7 0.0 2.0 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region Herpes_LMP1 PF05297.6 KPI37894.1 - 1.3 7.8 5.3 4.2 6.1 0.6 2.3 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Cys_Met_Meta_PP PF01053.15 KPI37895.1 - 3.6e-56 190.1 0.0 8.3e-56 188.9 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Spc97_Spc98 PF04130.8 KPI37897.1 - 2.4e-25 88.8 0.3 1.1e-22 80.1 0.1 2.2 2 0 0 2 2 2 2 Spc97 / Spc98 family Nup35_RRM_2 PF14605.1 KPI37897.1 - 0.0074 16.0 0.0 0.057 13.2 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif SKG6 PF08693.5 KPI37897.1 - 0.016 14.4 2.0 0.035 13.4 1.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF347 PF03988.7 KPI37897.1 - 0.14 12.0 1.1 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) AIP3 PF03915.8 KPI37898.1 - 2.8e-127 425.1 18.1 2.9e-123 411.9 12.5 2.5 1 1 0 1 1 1 1 Actin interacting protein 3 DUF948 PF06103.6 KPI37898.1 - 7.1 6.5 12.8 26 4.7 0.0 4.9 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) SKG6 PF08693.5 KPI37899.1 - 2.3e-08 33.2 1.9 4.3e-08 32.3 1.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PRCH PF03967.8 KPI37899.1 - 0.017 14.6 0.3 0.06 12.9 0.0 2.0 2 0 0 2 2 2 0 Photosynthetic reaction centre, H-chain N-terminal region Herpes_gE PF02480.11 KPI37899.1 - 0.023 13.0 0.0 0.032 12.4 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4448 PF14610.1 KPI37899.1 - 0.026 14.0 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM154 PF15102.1 KPI37899.1 - 0.03 14.0 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF1049 PF06305.6 KPI37899.1 - 0.091 12.2 0.1 0.091 12.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) MLANA PF14991.1 KPI37899.1 - 0.094 12.7 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein melan-A JAB PF01398.16 KPI37900.1 - 1.7e-05 24.5 0.0 4.5e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SDF PF00375.13 KPI37901.1 - 5.6e-88 295.3 34.1 6.6e-88 295.0 23.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family TB2_DP1_HVA22 PF03134.14 KPI37901.1 - 0.015 15.0 0.7 0.048 13.4 0.5 1.8 1 0 0 1 1 1 0 TB2/DP1, HVA22 family FAD_binding_3 PF01494.14 KPI37902.1 - 6.7e-25 87.8 0.1 2.5e-24 85.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI37902.1 - 3.2e-15 55.8 3.8 2.7e-07 29.8 0.0 2.9 2 1 0 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KPI37902.1 - 9.2e-06 24.5 2.2 0.0016 17.1 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 KPI37902.1 - 1e-05 25.4 0.9 2.4e-05 24.2 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI37902.1 - 4.4e-05 23.4 0.9 0.00015 21.7 0.6 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI37902.1 - 5.7e-05 22.1 2.1 0.00011 21.2 1.5 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KPI37902.1 - 8.1e-05 22.7 0.2 0.00024 21.2 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI37902.1 - 0.00022 20.4 0.4 0.00042 19.4 0.3 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 KPI37902.1 - 0.00026 20.2 0.7 0.023 13.7 0.0 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KPI37902.1 - 0.00056 18.9 2.1 0.33 9.8 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 KPI37902.1 - 0.016 13.7 1.6 0.1 11.0 1.2 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.2 KPI37902.1 - 0.033 13.2 3.1 0.09 11.8 2.2 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KPI37902.1 - 0.037 14.4 0.9 0.037 14.4 0.6 2.7 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI37902.1 - 0.089 11.6 4.3 0.39 9.5 3.0 1.9 1 1 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KPI37902.1 - 0.11 12.0 0.4 0.2 11.2 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UCR_hinge PF02320.11 KPI37902.1 - 0.12 12.3 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein NAD_binding_9 PF13454.1 KPI37902.1 - 0.17 11.6 2.7 12 5.6 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding NmrA PF05368.8 KPI37903.1 - 4.4e-09 35.9 0.0 7e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI37903.1 - 3.1e-08 33.8 0.0 4.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 KPI37903.1 - 0.00061 19.7 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 KPI37903.1 - 0.0019 17.2 0.0 0.0025 16.8 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase SGS PF05002.10 KPI37904.1 - 5.1e-22 77.4 7.6 5.1e-22 77.4 5.2 2.3 2 1 0 2 2 2 1 SGS domain CS PF04969.11 KPI37904.1 - 4.9e-12 46.2 1.4 1e-11 45.1 1.0 1.6 1 0 0 1 1 1 1 CS domain DUF2591 PF10765.4 KPI37904.1 - 0.095 12.9 0.7 0.39 10.9 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2591) TRI12 PF06609.8 KPI37905.1 - 2.4e-25 88.7 22.1 1.7e-19 69.4 11.1 2.3 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI37905.1 - 4.8e-14 51.8 48.7 1.4e-09 37.1 7.8 3.3 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI37905.1 - 2.3e-10 39.6 1.7 2.3e-10 39.6 1.2 3.6 2 1 0 3 3 3 1 Sugar (and other) transporter PIRT PF15099.1 KPI37905.1 - 4.5 6.5 5.4 0.67 9.1 0.7 1.9 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Yip1 PF04893.12 KPI37906.1 - 4.5e-05 23.0 12.7 0.013 14.9 8.7 2.3 1 1 0 1 1 1 1 Yip1 domain Fungal_trans PF04082.13 KPI37908.1 - 5.4e-14 51.6 0.4 5.7e-07 28.6 0.0 2.6 3 0 0 3 3 3 2 Fungal specific transcription factor domain YdjO PF14169.1 KPI37908.1 - 1.3 8.5 5.8 0.31 10.5 1.5 1.8 2 0 0 2 2 2 0 Cold-inducible protein YdjO Zn_clus PF00172.13 KPI37909.1 - 4.7e-08 32.8 9.8 4.7e-08 32.8 6.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KPI37909.1 - 0.00063 18.4 0.1 0.0013 17.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CFEM PF05730.6 KPI37911.1 - 4.4e-05 23.2 9.1 4.4e-05 23.2 6.3 2.4 2 0 0 2 2 2 1 CFEM domain 2-Hacid_dh_C PF02826.14 KPI37912.1 - 8.3e-45 152.1 0.0 9.9e-45 151.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KPI37912.1 - 3.9e-05 23.5 0.1 5.1e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UbiA PF01040.13 KPI37913.1 - 1.4e-26 93.2 18.2 2e-26 92.7 12.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF423 PF04241.10 KPI37913.1 - 0.078 12.9 4.2 0.084 12.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF423) Aldolase_II PF00596.16 KPI37914.1 - 0.0004 20.0 0.0 0.00048 19.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain LIM PF00412.17 KPI37916.1 - 1.6e-26 92.0 25.8 1.4e-12 47.4 1.7 4.6 5 0 0 5 5 5 3 LIM domain RRN7 PF11781.3 KPI37916.1 - 0.015 14.8 0.2 0.015 14.8 0.2 4.2 5 0 0 5 5 5 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn_ribbon_recom PF13408.1 KPI37916.1 - 0.023 14.9 0.8 0.023 14.9 0.5 2.4 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Auto_anti-p27 PF06677.7 KPI37916.1 - 0.076 12.7 7.3 1.4 8.7 0.4 3.6 3 1 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2321 PF10083.4 KPI37916.1 - 0.66 9.4 6.1 0.2 11.1 0.5 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) TP6A_N PF04406.9 KPI37917.1 - 1.8e-16 59.5 0.0 3.7e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 KPI37917.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) CDC50 PF03381.10 KPI37918.1 - 2.8e-95 318.6 0.0 4.1e-95 318.1 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF1688 PF07958.6 KPI37919.1 - 1.1e-172 574.2 0.0 1.4e-172 573.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Ring_hydroxyl_A PF00848.14 KPI37920.1 - 4.9e-34 117.8 2.2 1.2e-33 116.4 1.5 1.6 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 KPI37920.1 - 1.5e-12 46.9 0.0 2.8e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Eaf7 PF07904.8 KPI37921.1 - 4.6e-22 77.8 1.3 6.3e-22 77.3 0.0 1.9 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 PBP_sp32 PF07222.7 KPI37921.1 - 0.87 8.7 3.0 1.2 8.2 2.1 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CDC27 PF09507.5 KPI37921.1 - 2.9 7.0 14.4 4.4 6.4 10.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.7 KPI37921.1 - 4.7 5.0 12.2 6.2 4.6 8.5 1.3 1 0 0 1 1 1 0 Nop14-like family Methyltransf_23 PF13489.1 KPI37922.1 - 0.0064 16.2 0.0 0.0098 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF3602 PF12223.3 KPI37923.1 - 7.9e-13 48.6 26.5 0.00029 21.1 0.9 3.9 2 1 2 4 4 4 3 Protein of unknown function (DUF3602) Telomere_Sde2 PF13019.1 KPI37923.1 - 0.0004 20.0 0.1 0.002 17.8 0.0 2.0 2 0 0 2 2 2 1 Telomere stability and silencing Presenilin PF01080.12 KPI37923.1 - 0.043 12.6 0.2 0.043 12.6 0.1 2.1 2 0 0 2 2 2 0 Presenilin EthD PF07110.6 KPI37924.1 - 3e-09 37.6 0.0 6.1e-09 36.7 0.0 1.6 1 1 0 1 1 1 1 EthD domain Sina PF03145.11 KPI37926.1 - 0.018 14.7 0.5 0.027 14.1 0.3 1.1 1 0 0 1 1 1 0 Seven in absentia protein family DLH PF01738.13 KPI37927.1 - 5.7e-22 78.0 0.1 1.2e-21 76.9 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KPI37927.1 - 3.3e-07 30.1 0.0 4.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 KPI37927.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Rox3 PF08633.5 KPI37928.1 - 0.0087 16.4 2.0 0.071 13.4 2.0 1.8 2 0 0 2 2 2 1 Rox3 mediator complex subunit BLVR PF06375.6 KPI37928.1 - 0.082 12.7 3.6 0.085 12.6 1.3 1.7 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) RabGAP-TBC PF00566.13 KPI37929.1 - 1.3e-25 90.1 0.0 1.8e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Fungal_trans PF04082.13 KPI37930.1 - 1.1e-15 57.2 0.1 2.4e-15 56.1 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI37930.1 - 4.8e-06 26.3 2.5 9.3e-06 25.4 1.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_1 PF00126.22 KPI37930.1 - 0.0093 15.6 0.0 0.034 13.8 0.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family DnaJ PF00226.26 KPI37931.1 - 1.7e-06 27.6 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KPI37931.1 - 1.6e-05 24.7 0.0 2e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.1 KPI37931.1 - 3.8 6.9 5.7 0.27 10.5 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) His_Phos_2 PF00328.17 KPI37932.1 - 9e-10 38.3 0.0 1.2e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Mgm101p PF06420.7 KPI37933.1 - 0.091 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 PAP2 PF01569.16 KPI37934.1 - 1.7e-14 53.6 5.6 3e-14 52.8 3.8 1.5 1 1 0 1 1 1 1 PAP2 superfamily Ferric_reduct PF01794.14 KPI37934.1 - 0.045 13.8 4.1 0.1 12.6 2.9 1.6 1 0 0 1 1 1 0 Ferric reductase like transmembrane component 2TM PF13239.1 KPI37934.1 - 4.6 7.3 6.5 2.3 8.3 2.1 2.2 2 0 0 2 2 2 0 2TM domain DUF4131 PF13567.1 KPI37934.1 - 5.4 6.3 12.4 0.49 9.7 3.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Glyco_hydro_76 PF03663.9 KPI37936.1 - 6.6e-138 460.1 17.6 8.3e-138 459.7 12.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF1680 PF07944.7 KPI37936.1 - 9.3e-06 24.1 0.4 0.045 12.0 0.0 2.5 2 1 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_88 PF07470.8 KPI37936.1 - 0.015 14.3 10.7 0.2 10.6 2.0 3.0 1 1 0 2 2 2 0 Glycosyl Hydrolase Family 88 Acyl-CoA_dh_1 PF00441.19 KPI37937.1 - 1e-35 123.0 0.5 1.6e-35 122.4 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 KPI37937.1 - 9.1e-15 55.0 0.1 1.5e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KPI37937.1 - 1.4e-14 53.2 0.5 1.4e-13 50.0 0.3 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KPI37937.1 - 7.5e-10 39.3 0.1 4.1e-09 36.9 0.0 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.3 KPI37937.1 - 0.014 14.8 0.0 0.029 13.7 0.0 1.5 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal MFS_1 PF07690.11 KPI37938.1 - 2.2e-35 122.0 33.9 2.6e-35 121.7 23.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PUF PF00806.14 KPI37940.1 - 1.8e-35 118.3 6.9 1.2e-05 24.4 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat DUF2383 PF09537.5 KPI37940.1 - 0.056 13.6 0.8 0.18 12.0 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Spc7 PF08317.6 KPI37940.1 - 0.19 10.3 6.0 0.32 9.6 4.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein HeLo PF14479.1 KPI37940.1 - 0.57 9.8 6.5 1.3 8.7 1.9 2.2 2 0 0 2 2 2 0 Prion-inhibition and propagation IncA PF04156.9 KPI37940.1 - 3.3 7.2 7.5 5.4 6.5 5.2 1.3 1 0 0 1 1 1 0 IncA protein Flavoprotein PF02441.14 KPI37941.1 - 2.1e-40 137.3 0.3 2.6e-40 137.0 0.2 1.1 1 0 0 1 1 1 1 Flavoprotein p450 PF00067.17 KPI37942.1 - 1.3e-39 136.0 0.1 2.5e-26 92.2 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 Glyco_hydro_43 PF04616.9 KPI37943.1 - 5.6e-34 117.5 7.3 7e-34 117.2 5.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF377 PF04041.8 KPI37943.1 - 0.02 13.6 0.7 0.12 11.1 0.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF377) ADH_zinc_N_2 PF13602.1 KPI37944.1 - 0.0035 18.2 0.0 0.0039 18.0 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PAH PF02671.16 KPI37945.1 - 2e-39 132.9 1.4 5.5e-18 64.3 0.1 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KPI37945.1 - 1.1e-37 127.7 0.0 3.4e-37 126.2 0.0 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor Metallophos PF00149.23 KPI37946.1 - 4.6e-07 29.4 4.9 1.1e-06 28.1 3.4 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FAD_binding_3 PF01494.14 KPI37948.1 - 1.5e-14 53.8 0.1 2.8e-06 26.6 0.1 3.1 3 0 0 3 3 3 3 FAD binding domain SE PF08491.5 KPI37948.1 - 0.021 13.6 0.1 0.58 8.9 0.0 2.5 2 1 1 3 3 3 0 Squalene epoxidase UQ_con PF00179.21 KPI37949.1 - 7.2e-52 174.5 0.0 8e-52 174.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3237 PF11578.3 KPI37950.1 - 1.4e-33 115.3 0.3 3.6e-33 114.0 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) DUF572 PF04502.8 KPI37951.1 - 3.7e-71 240.0 18.4 4.6e-71 239.7 12.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 KPI37951.1 - 0.018 14.8 0.6 0.05 13.4 0.4 1.7 1 1 0 1 1 1 0 Benyvirus 14KDa protein DUF866 PF05907.8 KPI37951.1 - 0.024 14.1 0.2 0.024 14.1 0.2 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) zf-FCS PF06467.9 KPI37951.1 - 0.13 11.8 1.5 2.2 7.9 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Nop14 PF04147.7 KPI37951.1 - 9.2 4.0 24.0 12 3.6 16.7 1.0 1 0 0 1 1 1 0 Nop14-like family DUF3437 PF11919.3 KPI37953.1 - 1.7e-30 104.5 0.0 9.8e-30 102.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) CLASP_N PF12348.3 KPI37953.1 - 8.2e-06 25.3 0.0 0.2 10.9 0.0 3.1 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 KPI37953.1 - 0.00022 21.0 0.1 0.45 10.7 0.0 4.4 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 KPI37953.1 - 0.0062 16.7 0.1 7.7 6.8 0.0 4.2 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 KPI37953.1 - 0.11 13.0 0.1 8.5 7.0 0.0 4.2 4 0 0 4 4 4 0 HEAT-like repeat DUF3129 PF11327.3 KPI37957.1 - 4.6e-45 153.6 14.1 5e-45 153.5 6.6 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3129) Pkinase PF00069.20 KPI37958.1 - 8e-70 234.9 0.0 1.3e-69 234.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI37958.1 - 1.2e-35 122.8 0.0 7.6e-34 116.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KPI37958.1 - 0.0035 16.4 0.8 0.008 15.2 0.6 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KPI37958.1 - 0.0065 15.4 0.0 0.018 13.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like ADH_zinc_N PF00107.21 KPI37959.1 - 2.9e-12 46.2 0.0 5.1e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI37959.1 - 2.1e-05 24.2 0.0 8.7e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KPI37959.1 - 0.052 13.5 0.3 0.089 12.7 0.2 1.4 1 0 0 1 1 1 0 NADH(P)-binding MMS1_N PF10433.4 KPI37961.1 - 6e-67 225.9 0.0 9.9e-67 225.1 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Pyr_redox_3 PF13738.1 KPI37962.1 - 1.2e-22 80.9 0.0 5.3e-22 78.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI37962.1 - 2e-19 69.1 1.2 1.3e-14 53.3 0.1 2.7 1 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI37962.1 - 2.2e-10 40.4 0.0 6.5e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI37962.1 - 5.8e-10 38.5 0.0 4.3e-06 25.8 0.0 3.3 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KPI37962.1 - 0.00016 21.5 0.0 0.016 15.0 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI37962.1 - 0.0073 16.0 3.4 0.19 11.5 0.0 3.6 3 2 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KPI37962.1 - 0.045 12.8 0.0 0.18 10.8 0.0 1.9 2 0 0 2 2 2 0 Thi4 family BiPBP_C PF06832.7 KPI37962.1 - 0.15 11.9 0.0 0.46 10.4 0.0 1.8 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family HI0933_like PF03486.9 KPI37962.1 - 0.19 10.1 0.0 0.5 8.7 0.0 1.7 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.11 KPI37963.1 - 2.1e-29 102.3 37.8 2.1e-29 102.3 26.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.19 KPI37964.1 - 1.6e-35 122.6 0.0 2e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI37964.1 - 0.00068 19.5 0.0 0.091 12.6 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI37964.1 - 0.0043 17.0 0.1 0.011 15.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KPI37964.1 - 0.019 15.0 0.0 16 5.5 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase PPTA PF01239.17 KPI37964.1 - 0.078 12.3 0.9 0.17 11.2 0.6 1.6 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat FAD_binding_3 PF01494.14 KPI37964.1 - 0.097 11.7 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KPI37964.1 - 0.15 12.5 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lactamase_B PF00753.22 KPI37965.1 - 9.6e-22 77.5 0.8 1.5e-21 76.9 0.5 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI37965.1 - 3.2e-06 26.8 0.4 4.8e-06 26.2 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain WW PF00397.21 KPI37965.1 - 7.5e-05 22.5 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 WW domain CFEM PF05730.6 KPI37966.1 - 1.1e-08 34.7 6.1 1.1e-08 34.7 4.2 1.8 2 0 0 2 2 2 1 CFEM domain MFS_1 PF07690.11 KPI37967.1 - 1e-36 126.3 33.8 1.5e-36 125.8 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KPI37967.1 - 2.1e-11 42.7 3.8 4e-11 41.8 2.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ion_trans_2 PF07885.11 KPI37967.1 - 0.00087 18.9 0.5 0.00087 18.9 0.4 4.1 3 2 0 4 4 4 1 Ion channel MMPL PF03176.10 KPI37967.1 - 0.071 11.8 2.9 0.041 12.5 0.4 1.8 2 0 0 2 2 2 0 MMPL family Methyltransf_32 PF13679.1 KPI37968.1 - 4.3e-23 81.5 0.0 8.5e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.9 KPI37968.1 - 0.045 12.9 0.3 0.66 9.1 0.1 2.2 2 0 0 2 2 2 0 Methyltransferase TRM13 Methyltransf_31 PF13847.1 KPI37968.1 - 0.097 12.2 0.0 0.23 11.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain GST_N_3 PF13417.1 KPI37969.1 - 9.6e-11 41.7 0.0 1.9e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI37969.1 - 0.14 12.1 0.1 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Abhydrolase_6 PF12697.2 KPI37970.1 - 6.6e-28 98.1 0.0 7.7e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI37970.1 - 6.9e-13 48.6 0.0 1.8e-11 44.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI37970.1 - 1.6e-12 47.4 0.0 2.4e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KPI37970.1 - 0.0019 18.0 0.0 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KPI37970.1 - 0.026 13.7 0.0 0.051 12.7 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.15 KPI37970.1 - 0.029 13.7 0.0 0.062 12.7 0.0 1.5 2 0 0 2 2 2 0 Putative esterase Abhydro_lipase PF04083.11 KPI37970.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Peptidase_S28 PF05577.7 KPI37970.1 - 0.13 10.8 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DUF605 PF04652.11 KPI37972.1 - 5 6.4 15.7 6.3 6.0 10.9 1.2 1 0 0 1 1 1 0 Vta1 like Alk_phosphatase PF00245.15 KPI37974.1 - 5.6e-75 252.6 0.0 7.1e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase adh_short PF00106.20 KPI37975.1 - 6e-25 88.0 0.0 8e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI37975.1 - 1.9e-21 76.9 0.0 2.3e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI37975.1 - 6.8e-13 48.6 0.0 1.1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.10 KPI37975.1 - 0.052 13.3 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.14 KPI37975.1 - 0.064 11.9 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4149 PF13664.1 KPI37976.1 - 6.2e-22 77.5 1.4 9.1e-22 77.0 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) IBR PF01485.16 KPI37977.1 - 5.8e-19 67.7 36.3 2.7e-13 49.5 2.0 3.9 3 1 1 4 4 4 2 IBR domain RWD PF05773.17 KPI37977.1 - 6.9e-16 58.1 0.0 1.3e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 KPI37977.1 - 4.7e-05 23.1 10.2 4.7e-05 23.1 7.1 3.7 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 KPI37977.1 - 0.0049 16.5 10.8 0.0049 16.5 7.5 3.7 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KPI37977.1 - 0.018 15.0 12.2 0.018 15.0 8.5 4.1 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KPI37977.1 - 1.3 8.7 22.2 0.035 13.8 5.3 2.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.1 KPI37978.1 - 5.2e-09 35.8 6.5 9.3e-09 34.9 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KPI37978.1 - 1.6e-05 24.9 3.5 3.5e-05 23.8 2.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KPI37978.1 - 0.00013 21.6 5.2 0.0003 20.5 3.6 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KPI37978.1 - 0.00023 21.1 4.0 0.00044 20.2 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI37978.1 - 0.00068 19.3 4.7 0.0011 18.6 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KPI37978.1 - 0.0034 17.0 2.7 0.0034 17.0 1.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KPI37978.1 - 0.0048 16.8 3.5 0.012 15.6 2.4 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 KPI37978.1 - 0.037 13.7 5.9 0.06 13.0 4.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 KPI37978.1 - 0.037 14.0 2.4 0.081 12.9 1.7 1.6 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 KPI37978.1 - 0.13 12.0 5.0 0.21 11.3 3.5 1.3 1 0 0 1 1 1 0 PHD-finger SKG6 PF08693.5 KPI37979.1 - 0.061 12.6 1.6 0.1 11.9 1.1 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Alpha_GJ PF03229.8 KPI37979.1 - 0.23 11.8 2.3 0.44 10.8 0.1 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J EphA2_TM PF14575.1 KPI37979.1 - 1.3 9.5 0.0 1.3 9.5 0.0 2.8 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain zf-BED PF02892.10 KPI37981.1 - 0.0013 18.4 1.0 0.0025 17.5 0.7 1.5 1 0 0 1 1 1 1 BED zinc finger zf-C2H2 PF00096.21 KPI37981.1 - 0.011 16.0 3.5 0.029 14.6 2.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI37981.1 - 0.16 12.3 1.6 0.36 11.2 1.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Fungal_trans PF04082.13 KPI37982.1 - 7.8e-19 67.5 0.0 1.3e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_17 PF00332.13 KPI37983.1 - 9.1e-11 41.3 0.2 1.8e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Methyltransf_6 PF03737.10 KPI37983.1 - 1e-10 41.6 0.0 2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase UQ_con PF00179.21 KPI37984.1 - 2.8e-22 78.6 0.0 4.5e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TPP_enzyme_N PF02776.13 KPI37987.1 - 2.3e-27 95.5 0.0 4.4e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KPI37987.1 - 2.1e-23 82.5 0.0 5.9e-23 81.1 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KPI37987.1 - 1.1e-09 38.0 0.0 2.7e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain APC8 PF04049.8 KPI37988.1 - 6.7e-51 171.7 0.2 2.1e-50 170.1 0.1 1.8 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.1 KPI37988.1 - 2.4e-20 71.9 3.3 4.5e-07 29.4 0.1 5.9 4 1 1 5 5 5 3 TPR repeat TPR_1 PF00515.23 KPI37988.1 - 1.2e-19 69.0 6.7 0.0002 20.8 0.0 7.2 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 KPI37988.1 - 3.3e-17 61.4 14.1 0.0054 17.2 0.0 8.0 7 1 1 8 8 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 KPI37988.1 - 1.3e-15 57.6 14.9 2.5e-05 24.8 0.1 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 KPI37988.1 - 2.5e-15 55.0 12.9 0.046 13.6 0.0 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KPI37988.1 - 2.5e-14 51.8 4.0 0.0001 21.8 0.0 6.6 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KPI37988.1 - 8.3e-13 48.4 7.5 0.014 15.6 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 KPI37988.1 - 2.2e-09 36.7 1.6 2.8 8.3 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KPI37988.1 - 4.3e-09 36.1 13.9 0.15 12.0 1.1 6.7 5 1 1 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 KPI37988.1 - 4.4e-09 36.3 12.2 0.25 11.5 0.1 5.9 6 1 0 6 6 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KPI37988.1 - 1.1e-07 31.0 5.0 0.027 14.2 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KPI37988.1 - 1.2e-07 31.7 12.5 2.7 8.6 0.0 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.1 KPI37988.1 - 6e-07 28.8 1.7 8.1e-05 21.8 0.2 3.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KPI37988.1 - 1.7e-05 24.5 7.2 0.0058 16.4 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 KPI37988.1 - 9.2e-05 22.2 5.9 0.22 11.5 0.2 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 KPI37988.1 - 0.018 15.3 1.8 0.018 15.3 1.3 2.4 2 0 0 2 2 1 0 Tetratricopeptide repeat Cu-oxidase_3 PF07732.10 KPI37991.1 - 6.7e-29 100.0 0.9 4.8e-28 97.2 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 KPI37991.1 - 2.4e-25 89.2 0.0 8.4e-25 87.5 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KPI37991.1 - 4.9e-16 58.4 8.2 4.6e-14 52.0 0.6 3.5 2 2 0 2 2 2 2 Multicopper oxidase FAD_binding_3 PF01494.14 KPI37992.1 - 6.1e-11 41.9 0.1 4.5e-06 25.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KPI37992.1 - 4.1e-05 23.5 0.0 0.00011 22.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI37992.1 - 0.00017 20.6 0.0 0.00027 19.9 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI37992.1 - 0.0083 15.0 0.0 0.018 13.8 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KPI37992.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI37992.1 - 0.031 13.2 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 KPI37992.1 - 0.048 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI37992.1 - 0.091 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI37992.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family TPT PF03151.11 KPI37993.1 - 8.8e-16 57.9 0.2 8.8e-16 57.9 0.1 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KPI37993.1 - 1.8e-06 27.1 2.1 2.6e-06 26.5 1.5 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KPI37993.1 - 3.2e-06 27.1 5.3 3.2e-06 27.1 3.7 2.7 1 1 1 2 2 2 1 EamA-like transporter family M-factor PF03855.8 KPI37993.1 - 0.046 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 M-factor TauE PF01925.14 KPI37993.1 - 0.075 12.4 4.1 0.12 11.8 2.8 1.3 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE 7TMR-DISM_7TM PF07695.6 KPI37993.1 - 0.16 11.6 9.4 0.07 12.7 0.7 2.4 1 1 0 2 2 2 0 7TM diverse intracellular signalling EmrE PF13536.1 KPI37993.1 - 1.6 8.9 10.4 0.14 12.3 2.1 2.6 1 1 0 2 2 2 0 Multidrug resistance efflux transporter AMP-binding PF00501.23 KPI37994.1 - 7.7e-96 321.0 0.1 9.3e-96 320.7 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI37994.1 - 6.8e-12 46.1 0.0 3e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain VWA_CoxE PF05762.9 KPI37994.1 - 0.028 13.5 0.1 0.054 12.6 0.1 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein zf-4CXXC_R1 PF10497.4 KPI37995.1 - 2e-08 34.3 6.2 2e-08 34.3 4.3 2.1 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 JmjC PF02373.17 KPI37995.1 - 4e-08 33.4 0.5 7.1e-07 29.4 0.4 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 KPI37995.1 - 0.0066 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Ribonucleas_3_3 PF14622.1 KPI37997.1 - 1.4e-24 86.4 0.0 2.6e-24 85.6 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KPI37997.1 - 0.0004 20.7 0.0 0.00081 19.8 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain DUF1020 PF06255.8 KPI37997.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1020) Kelch_6 PF13964.1 KPI37998.1 - 2.6e-34 115.9 8.2 1.9e-09 37.2 0.1 6.5 1 1 5 6 6 6 6 Kelch motif Kelch_1 PF01344.20 KPI37998.1 - 4e-30 103.0 0.9 3e-08 33.0 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 KPI37998.1 - 1.2e-28 98.5 13.1 5.9e-06 26.2 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 KPI37998.1 - 3.6e-28 97.0 13.5 1.1e-06 28.2 0.1 6.9 6 2 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 KPI37998.1 - 2.9e-19 67.9 7.2 2.8e-05 23.6 0.5 7.0 6 2 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 KPI37998.1 - 4.4e-17 61.6 8.0 0.0018 18.2 0.0 6.5 6 1 0 6 6 6 5 Kelch motif TPR_11 PF13414.1 KPI37999.1 - 2.8e-11 42.8 0.1 1.2e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KPI37999.1 - 1.1e-08 34.3 0.0 0.019 14.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KPI37999.1 - 1.3e-08 34.0 0.0 0.093 12.3 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KPI37999.1 - 1.5e-06 28.0 0.2 0.0015 18.3 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat DnaJ PF00226.26 KPI37999.1 - 0.003 17.2 0.0 0.0083 15.8 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_7 PF13176.1 KPI37999.1 - 0.0054 16.4 0.0 6 6.9 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KPI37999.1 - 0.016 15.8 2.2 1.8 9.3 0.2 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KPI37999.1 - 0.073 13.7 4.0 0.92 10.3 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 KPI37999.1 - 0.085 12.7 0.3 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 KPI37999.1 - 0.089 12.9 0.0 9.5 6.4 0.0 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Prenyltrans PF00432.16 KPI38000.1 - 1.1e-31 108.0 4.0 2.4e-10 39.7 0.0 5.1 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KPI38000.1 - 4.5e-27 94.6 5.8 3.6e-09 37.0 0.1 6.2 4 1 2 6 6 6 5 Prenyltransferase-like Prenyltrans_1 PF13243.1 KPI38000.1 - 9.3e-26 89.9 3.7 6.9e-11 42.1 0.1 6.4 5 2 1 6 6 6 4 Prenyltransferase-like Mago-bind PF09282.5 KPI38000.1 - 0.0044 16.5 0.0 0.06 12.9 0.0 2.3 2 0 0 2 2 2 1 Mago binding A2M_comp PF07678.9 KPI38000.1 - 0.042 13.0 0.0 0.34 10.1 0.0 2.4 1 1 1 2 2 2 0 A-macroglobulin complement component Pec_lyase PF09492.5 KPI38000.1 - 0.34 10.0 7.4 7.3 5.6 0.0 4.3 5 1 1 6 6 6 0 Pectic acid lyase Abhydrolase_3 PF07859.8 KPI38001.1 - 6.4e-28 97.7 0.2 6.2e-27 94.5 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KPI38001.1 - 3e-05 22.9 0.2 0.00012 20.9 0.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KPI38001.1 - 0.099 11.8 0.2 0.18 11.0 0.2 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Longin PF13774.1 KPI38001.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Regulated-SNARE-like domain DUF3958 PF13125.1 KPI38001.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) GST_N_3 PF13417.1 KPI38002.1 - 2.5e-17 62.8 0.0 5.5e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI38002.1 - 1.1e-12 47.7 0.0 2.4e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KPI38002.1 - 3.8e-06 26.7 0.1 1.6e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KPI38002.1 - 0.00082 19.5 0.1 0.0096 16.0 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KPI38002.1 - 0.0021 18.0 0.0 0.048 13.6 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KPI38002.1 - 0.086 13.3 0.0 0.25 11.8 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FAR1 PF03101.10 KPI38002.1 - 0.21 12.1 2.9 0.74 10.3 2.0 1.9 1 0 0 1 1 1 0 FAR1 DNA-binding domain Arginosuc_synth PF00764.14 KPI38004.1 - 3.5e-146 487.2 0.0 3.9e-146 487.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Apc15p PF05841.6 KPI38005.1 - 8.1e-17 62.1 3.3 8.1e-17 62.1 2.3 3.8 4 1 0 4 4 4 2 Apc15p protein KOW PF00467.24 KPI38006.1 - 0.0049 16.5 0.3 0.01 15.5 0.2 1.5 1 0 0 1 1 1 1 KOW motif Pmp3 PF01679.12 KPI38007.1 - 1.7e-19 69.2 7.9 2.1e-19 68.9 5.5 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator NapE PF06796.6 KPI38007.1 - 0.27 10.5 2.7 0.39 10.0 1.9 1.3 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE AMP-binding PF00501.23 KPI38008.1 - 4.6e-44 150.4 0.0 6.4e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Helicase_C_3 PF13625.1 KPI38009.1 - 1.7e-27 95.7 0.0 3.3e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI38009.1 - 2.4e-15 56.8 0.0 5e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KPI38009.1 - 3.1e-13 49.2 0.1 5.1e-13 48.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KPI38009.1 - 1.6e-10 40.6 0.0 4.7e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KPI38009.1 - 5.9e-08 32.3 0.0 1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.1 KPI38009.1 - 0.00011 21.1 0.1 0.00019 20.3 0.1 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Peptidase_S37 PF05576.6 KPI38009.1 - 0.077 11.4 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 PS-10 peptidase S37 GLTP PF08718.6 KPI38010.1 - 5.9e-29 101.0 0.0 8.3e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) EF-hand_1 PF00036.27 KPI38010.1 - 0.06 12.6 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 EF hand DUF4048 PF13257.1 KPI38013.1 - 1.4e-25 90.3 15.3 1.4e-25 90.3 10.6 3.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4048) Ferric_reduct PF01794.14 KPI38014.1 - 9.7e-12 45.0 14.1 2.7e-11 43.6 9.8 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KPI38014.1 - 2.1e-11 43.6 0.0 4.6e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KPI38014.1 - 0.07 13.0 0.0 0.28 11.0 0.0 1.9 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Gemini_mov PF01708.11 KPI38014.1 - 1.1 8.8 7.0 1.9 8.0 0.0 3.3 3 0 0 3 3 3 0 Geminivirus putative movement protein Abhydrolase_6 PF12697.2 KPI38015.1 - 9.1e-18 64.9 0.3 3.8e-17 62.9 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI38015.1 - 6.7e-08 32.3 0.0 5.6e-07 29.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI38015.1 - 2.1e-05 24.3 0.0 0.00026 20.7 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KPI38015.1 - 0.016 14.8 0.4 0.74 9.3 0.0 2.4 2 0 0 2 2 2 0 Serine hydrolase Fungal_trans PF04082.13 KPI38017.1 - 2.4e-08 33.1 0.1 3.9e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI38017.1 - 0.00012 21.9 7.7 0.00022 21.0 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 KPI38018.1 - 1.4e-13 51.2 0.0 2e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI38018.1 - 2.8e-09 36.8 0.0 5.8e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI38018.1 - 5.4e-06 26.1 0.0 2.1e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KPI38018.1 - 0.0092 15.8 0.2 0.028 14.2 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase PGAP1 PF07819.8 KPI38018.1 - 0.043 13.4 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.11 KPI38018.1 - 0.061 12.7 0.0 6.1 6.2 0.0 2.7 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KPI38018.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glutaredoxin PF00462.19 KPI38019.1 - 1.7e-10 40.7 0.5 3.9e-09 36.3 0.0 3.1 3 1 0 3 3 3 1 Glutaredoxin GST_N_3 PF13417.1 KPI38019.1 - 0.13 12.5 0.1 0.37 11.0 0.1 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PQ-loop PF04193.9 KPI38020.1 - 1.1e-21 76.1 1.3 3.8e-14 51.9 0.1 2.5 2 0 0 2 2 2 2 PQ loop repeat Transglut_core PF01841.14 KPI38020.1 - 6.3e-13 48.9 0.1 1.4e-12 47.8 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_9 PF14604.1 KPI38020.1 - 7e-05 22.3 0.0 0.00016 21.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KPI38020.1 - 0.0011 18.2 0.0 0.0029 16.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain Fungal_trans PF04082.13 KPI38021.1 - 3.2e-21 75.3 1.4 5.8e-20 71.2 1.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KPI38022.1 - 8e-42 142.8 0.8 1.4e-41 142.0 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI38022.1 - 3.2e-08 33.3 8.0 6e-08 32.4 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KPI38023.1 - 1.4e-19 70.0 30.8 1.4e-19 70.0 21.3 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_61 PF03443.9 KPI38024.1 - 2.6e-55 187.6 0.0 3.4e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 FAA_hydrolase PF01557.13 KPI38025.1 - 3.8e-53 180.1 0.0 7.1e-53 179.2 0.0 1.4 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family FAD_binding_3 PF01494.14 KPI38026.1 - 1.5e-08 34.0 0.0 3.6e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KPI38026.1 - 0.0018 18.2 0.0 0.0045 16.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF134 PF02001.11 KPI38026.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF134 Epimerase PF01370.16 KPI38027.1 - 1.5e-17 63.8 0.0 2.2e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI38027.1 - 3.1e-13 50.1 0.4 6e-13 49.2 0.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KPI38027.1 - 1.5e-10 40.2 0.0 1.9e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KPI38027.1 - 1e-07 31.1 0.2 1.4e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KPI38027.1 - 4.7e-06 25.7 0.0 1e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KPI38027.1 - 8.4e-06 25.7 0.2 1.5e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KPI38027.1 - 0.0013 18.0 0.1 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 KPI38027.1 - 0.012 15.3 1.0 0.045 13.4 0.7 1.8 1 1 0 1 1 1 0 KR domain MIP-T3 PF10243.4 KPI38028.1 - 0.027 12.9 7.2 0.042 12.3 5.0 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FAD_binding_3 PF01494.14 KPI38029.1 - 2.5e-07 30.0 0.0 2.9e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI38029.1 - 6e-06 25.3 10.0 0.011 14.6 4.0 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KPI38029.1 - 4e-05 22.2 1.5 0.00011 20.7 1.0 1.7 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KPI38029.1 - 0.00068 19.9 3.1 0.036 14.4 0.6 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI38029.1 - 0.001 19.1 0.2 0.0016 18.5 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI38029.1 - 0.0065 16.3 2.4 0.018 14.8 1.7 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI38029.1 - 0.0075 16.2 5.0 0.015 15.2 2.5 2.2 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KPI38029.1 - 0.016 13.8 4.7 0.041 12.5 1.4 1.9 1 1 1 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 KPI38029.1 - 0.032 13.8 0.2 0.055 13.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KPI38029.1 - 0.046 12.5 7.3 0.041 12.7 4.1 1.6 1 1 1 2 2 2 0 FAD binding domain Methyltransf_16 PF10294.4 KPI38029.1 - 0.074 12.5 0.1 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Lycopene_cycl PF05834.7 KPI38029.1 - 0.092 11.6 3.9 0.29 10.0 2.7 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 KPI38029.1 - 0.13 11.3 0.4 0.29 10.1 0.1 1.7 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 KPI38029.1 - 0.17 10.6 2.1 0.27 10.0 1.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 KPI38029.1 - 1.5 7.8 4.6 1.7 7.6 3.2 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase DUF4459 PF14673.1 KPI38030.1 - 0.28 10.8 0.0 0.5 10.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) MFS_1 PF07690.11 KPI38031.1 - 8.7e-26 90.4 36.6 3.7e-25 88.3 25.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Syndecan PF01034.15 KPI38031.1 - 0.15 11.7 0.0 0.15 11.7 0.0 2.3 3 0 0 3 3 3 0 Syndecan domain NDUF_B6 PF09782.4 KPI38031.1 - 0.15 11.8 0.7 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit DcpS_C PF11969.3 KPI38033.1 - 8.3e-26 90.5 0.2 2.3e-25 89.1 0.1 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KPI38033.1 - 4.4e-18 65.6 0.0 8.6e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal adh_short PF00106.20 KPI38035.1 - 1.3e-12 47.9 0.0 2.7e-12 46.9 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KPI38035.1 - 2.1e-05 24.2 0.0 3.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI38035.1 - 0.00058 19.6 0.0 0.00084 19.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KPI38035.1 - 0.005 16.6 0.6 0.063 13.0 0.2 2.4 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KPI38035.1 - 0.13 12.3 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding Amidase PF01425.16 KPI38036.1 - 3.1e-103 346.0 0.0 3.6e-103 345.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Ald_Xan_dh_C2 PF02738.13 KPI38037.1 - 1.1e-176 588.4 0.9 1.4e-176 588.0 0.7 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KPI38037.1 - 3.7e-37 127.3 0.0 8.5e-37 126.2 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 KPI38037.1 - 1.2e-32 111.8 0.0 5.1e-32 109.8 0.0 2.2 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 KPI38037.1 - 4.1e-25 87.4 0.0 9.9e-25 86.2 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.17 KPI38037.1 - 3.7e-24 84.9 0.0 1.9e-23 82.6 0.0 2.2 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.22 KPI38037.1 - 1.2e-06 28.2 0.0 3.6e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Sugar_tr PF00083.19 KPI38038.1 - 3.1e-74 250.1 22.8 3.7e-74 249.9 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI38038.1 - 5e-20 71.5 35.8 6.8e-20 71.0 20.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI38038.1 - 4.6e-05 22.0 9.2 4.6e-05 22.0 6.4 3.1 2 2 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KPI38038.1 - 0.0019 16.4 1.2 0.0019 16.4 0.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.27 KPI38039.1 - 9.7e-41 136.2 7.2 1.1e-10 41.0 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KPI38039.1 - 1.2e-07 30.2 13.9 0.02 13.0 0.0 4.8 2 2 3 5 5 5 3 Nucleoporin Nup120/160 APG6 PF04111.7 KPI38039.1 - 0.00075 18.6 1.5 0.0012 18.0 1.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 IncA PF04156.9 KPI38039.1 - 0.049 13.2 3.0 0.079 12.5 2.1 1.2 1 0 0 1 1 1 0 IncA protein Seryl_tRNA_N PF02403.17 KPI38039.1 - 0.071 13.1 2.1 0.16 11.9 1.5 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Nucleoporin_N PF08801.6 KPI38039.1 - 0.11 11.2 0.0 6.2 5.4 0.0 2.9 3 1 0 3 3 3 0 Nup133 N terminal like Cortex-I_coil PF09304.5 KPI38039.1 - 0.16 12.0 5.4 0.45 10.5 1.6 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil TPR_MLP1_2 PF07926.7 KPI38039.1 - 1.8 8.2 5.5 2.7 7.7 1.4 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Pro_isomerase PF00160.16 KPI38042.1 - 2.8e-46 157.5 0.1 3.3e-46 157.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD L51_S25_CI-B8 PF05047.11 KPI38043.1 - 1.6e-09 37.3 0.1 2.2e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain FAD_binding_3 PF01494.14 KPI38044.1 - 0.011 14.8 0.1 0.021 13.8 0.0 1.4 1 1 1 2 2 2 0 FAD binding domain SE PF08491.5 KPI38044.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase KilA-N PF04383.8 KPI38045.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 KilA-N domain T2SM_b PF10741.4 KPI38045.1 - 0.29 10.7 3.5 1.1 8.9 1.9 2.2 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M subtype b HET PF06985.6 KPI38046.1 - 1.7e-29 102.7 0.1 3.5e-29 101.7 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SCIMP PF15050.1 KPI38047.1 - 4.2 7.2 12.0 0.58 10.0 1.9 3.1 2 1 0 2 2 2 0 SCIMP protein DNA_ligase_A_M PF01068.16 KPI38050.1 - 1.3e-44 152.0 0.0 3e-44 150.8 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KPI38050.1 - 9.8e-42 142.7 0.2 3.2e-41 141.0 0.0 2.0 3 0 0 3 3 3 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KPI38050.1 - 1.9e-18 66.6 1.2 1.2e-17 64.0 0.0 2.8 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KPI38050.1 - 9.3e-11 41.7 0.0 2.4e-07 30.7 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 KPI38050.1 - 1.2e-06 28.3 0.5 0.0055 16.4 0.1 3.9 3 1 0 3 3 3 1 mRNA capping enzyme, catalytic domain DNA_ligase_IV PF11411.3 KPI38050.1 - 0.00074 19.1 0.5 0.0023 17.6 0.3 1.9 1 0 0 1 1 1 1 DNA ligase IV SnoaL_4 PF13577.1 KPI38051.1 - 7.1e-18 64.7 0.3 9.2e-18 64.3 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.2 KPI38051.1 - 0.00044 20.7 0.0 0.00063 20.2 0.0 1.3 1 0 0 1 1 1 1 Putative lumazine-binding SnoaL_3 PF13474.1 KPI38051.1 - 0.062 13.3 0.1 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.1 KPI38051.1 - 0.092 12.9 0.1 0.19 11.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 KPI38051.1 - 0.1 13.0 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain GILT PF03227.11 KPI38052.1 - 4.7e-11 42.4 0.1 1.2e-10 41.1 0.0 1.7 1 1 1 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DUF1308 PF07000.6 KPI38053.1 - 1.3e-49 168.8 0.0 2.1e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Ric8 PF10165.4 KPI38053.1 - 0.049 12.4 0.1 0.082 11.7 0.1 1.2 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn zf-C3HC4_4 PF15227.1 KPI38054.1 - 7.8e-08 32.0 14.7 2.8e-07 30.2 10.2 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KPI38054.1 - 7.4e-07 29.0 13.6 7.4e-07 29.0 9.4 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KPI38054.1 - 1.7e-06 27.5 9.7 1.7e-06 27.5 6.7 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KPI38054.1 - 2.1e-06 27.4 14.2 2.1e-06 27.4 9.8 2.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KPI38054.1 - 2.4e-06 27.0 12.1 2.4e-06 27.0 8.4 2.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI38054.1 - 1.6e-05 24.5 10.9 1.6e-05 24.5 7.5 3.0 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KPI38054.1 - 8.8e-05 22.1 6.4 0.00021 20.9 4.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-TRAF PF02176.13 KPI38054.1 - 0.002 18.4 7.1 0.002 18.4 5.0 4.0 2 1 3 5 5 5 4 TRAF-type zinc finger HR1 PF02185.11 KPI38054.1 - 0.05 13.3 0.6 0.05 13.3 0.4 1.8 2 0 0 2 2 2 0 Hr1 repeat CorA PF01544.13 KPI38055.1 - 0.02 13.9 8.1 0.18 10.8 5.0 2.6 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Sugar_tr PF00083.19 KPI38056.1 - 2.1e-109 366.1 15.0 4.1e-109 365.1 10.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI38056.1 - 1.3e-15 56.9 29.2 1.6e-14 53.4 18.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Chorion_2 PF03964.10 KPI38057.1 - 1.2 9.7 10.4 29 5.2 0.5 3.7 3 0 0 3 3 3 0 Chorion family 2 Sugar_tr PF00083.19 KPI38058.1 - 2.2e-28 99.0 12.6 2.4e-28 98.9 8.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter NB PF04159.8 KPI38058.1 - 0.76 9.5 3.1 5.3 6.8 0.1 3.2 2 1 2 4 4 4 0 NB glycoprotein ELF PF03317.8 KPI38058.1 - 3.5 6.8 4.7 0.37 10.0 0.3 1.6 2 0 0 2 2 2 0 ELF protein Glycos_transf_1 PF00534.15 KPI38059.1 - 2.8e-31 108.2 0.0 7.2e-30 103.6 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KPI38059.1 - 2.8e-12 47.0 0.2 2.8e-12 47.0 0.2 3.0 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 KPI38059.1 - 9e-10 38.5 0.1 9.3e-08 31.9 0.0 3.1 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KPI38059.1 - 1.6e-07 31.5 0.0 2.8e-06 27.5 0.0 2.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KPI38059.1 - 2.7e-06 27.5 0.0 7.6e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Fungal_trans_2 PF11951.3 KPI38059.1 - 0.055 12.0 0.6 0.089 11.3 0.1 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain Arrestin_C PF02752.17 KPI38060.1 - 3.9e-14 52.9 0.0 2.9e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Ribosomal_L4 PF00573.17 KPI38061.1 - 4e-38 130.7 0.0 6.3e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Glyco_transf_90 PF05686.7 KPI38062.1 - 3.3e-14 52.3 5.8 2.6e-05 23.0 0.0 4.2 3 1 0 3 3 3 3 Glycosyl transferase family 90 FAD_binding_3 PF01494.14 KPI38063.1 - 4.9e-74 249.5 0.0 6.3e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KPI38063.1 - 2.5e-36 124.8 0.0 4e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 KPI38063.1 - 0.0016 17.3 0.0 0.0041 16.0 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KPI38063.1 - 0.0094 16.3 0.0 0.069 13.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI38063.1 - 0.019 14.9 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KPI38063.1 - 0.02 13.8 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 KPI38063.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 KPI38063.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KPI38063.1 - 0.2 10.0 0.0 0.36 9.2 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 KPI38064.1 - 2.7e-29 102.1 0.3 3.3e-29 101.9 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI38064.1 - 7.9e-05 21.6 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KPI38064.1 - 0.00051 20.0 0.3 0.0017 18.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KPI38064.1 - 0.0041 16.2 0.0 0.0041 16.2 0.0 1.8 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.9 KPI38064.1 - 0.022 14.6 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like_2 PF13013.1 KPI38065.1 - 0.092 12.4 0.2 0.31 10.7 0.2 1.8 1 1 1 2 2 2 0 F-box-like domain zf-RING_2 PF13639.1 KPI38066.1 - 1.6e-06 27.7 6.6 3.2e-06 26.8 4.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 KPI38066.1 - 5.8e-05 22.8 4.2 0.0001 22.0 2.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KPI38066.1 - 0.0019 18.2 5.9 0.0049 16.9 4.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 KPI38066.1 - 0.19 11.7 6.7 0.64 10.0 4.2 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 KPI38066.1 - 0.49 10.4 5.8 1.1 9.3 4.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 KPI38066.1 - 0.53 10.0 6.6 1.1 8.9 4.6 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 KPI38066.1 - 0.59 9.7 7.7 3.4 7.3 1.6 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain CENP-T PF15511.1 KPI38066.1 - 2.4 7.2 27.9 3.7 6.6 19.4 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T UPF0547 PF10571.4 KPI38066.1 - 4.9 6.9 8.2 17 5.2 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 adh_short PF00106.20 KPI38067.1 - 1.6e-22 80.1 2.6 2.9e-12 46.8 0.0 2.4 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.1 KPI38067.1 - 3.7e-22 79.2 0.4 1.3e-15 57.8 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI38067.1 - 3.5e-08 33.3 1.4 1.5e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 KR domain DUF4185 PF13810.1 KPI38068.1 - 3.8e-12 45.7 7.3 2.1e-11 43.3 5.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4185) AMP-binding PF00501.23 KPI38070.1 - 7e-28 97.1 0.0 1.2e-21 76.6 0.0 2.4 1 1 1 2 2 2 2 AMP-binding enzyme Polysacc_deac_1 PF01522.16 KPI38071.1 - 2.2e-20 72.5 0.0 3.9e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF4629 PF15442.1 KPI38072.1 - 0.027 14.5 5.8 0.036 14.2 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) DUF3807 PF12720.2 KPI38072.1 - 2.6 8.1 6.0 29 4.7 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) HET PF06985.6 KPI38073.1 - 1.7e-16 60.5 0.1 2.2e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glutaredoxin PF00462.19 KPI38074.1 - 7.5e-18 64.2 0.1 1.1e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.1 KPI38074.1 - 0.0026 17.7 0.0 0.0035 17.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.1 KPI38074.1 - 0.0033 16.9 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin GST_N_3 PF13417.1 KPI38074.1 - 0.0037 17.4 0.0 0.0055 16.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.1 KPI38074.1 - 0.024 14.8 0.3 0.04 14.1 0.2 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 KPI38074.1 - 0.025 14.8 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) TraF PF13728.1 KPI38074.1 - 0.035 13.6 0.0 0.045 13.2 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Redoxin PF08534.5 KPI38074.1 - 0.038 13.5 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 Redoxin Phage_T4_gp36 PF03903.8 KPI38074.1 - 0.042 13.9 0.4 0.047 13.7 0.3 1.1 1 0 0 1 1 1 0 Phage T4 tail fibre Aldo_ket_red PF00248.16 KPI38075.1 - 6.4e-68 228.6 0.0 7.9e-68 228.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Apc13p PF05839.6 KPI38076.1 - 1.6e-13 50.4 0.0 1.4e-08 34.5 0.0 2.4 2 0 0 2 2 2 2 Apc13p protein Aldedh PF00171.17 KPI38077.1 - 1.6e-111 372.8 0.0 1.1e-57 195.4 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Mg_chelatase PF01078.16 KPI38077.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SnoaL_4 PF13577.1 KPI38078.1 - 2.6e-14 53.2 0.9 3.3e-14 52.8 0.6 1.1 1 0 0 1 1 1 1 SnoaL-like domain TCP PF03634.8 KPI38078.1 - 0.15 12.4 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 TCP family transcription factor p450 PF00067.17 KPI38079.1 - 8.9e-71 238.7 0.0 1e-70 238.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 VacJ PF04333.8 KPI38079.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 VacJ like lipoprotein tRNA_bind PF01588.15 KPI38080.1 - 2e-19 69.2 0.1 2.8e-17 62.3 0.1 2.5 1 1 0 1 1 1 1 Putative tRNA binding domain TRAM_LAG1_CLN8 PF03798.11 KPI38081.1 - 2e-35 122.1 20.7 3.5e-35 121.3 14.3 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 KPI38081.1 - 1.2e-20 72.7 1.5 2.9e-20 71.5 0.0 2.3 2 1 0 2 2 2 1 TRAM1-like protein Surfac_D-trimer PF09006.6 KPI38082.1 - 0.11 12.2 1.6 13 5.6 0.1 2.4 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation adh_short PF00106.20 KPI38083.1 - 4.1e-32 111.3 3.8 4.8e-32 111.1 2.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI38083.1 - 1.5e-18 67.4 0.1 1.7e-18 67.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI38083.1 - 2.8e-13 49.9 2.7 3.4e-13 49.6 1.9 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KPI38083.1 - 0.0038 16.1 0.0 0.005 15.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KPI38083.1 - 0.0041 16.5 0.1 0.012 15.0 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KPI38083.1 - 0.011 14.8 0.2 0.014 14.3 0.2 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase 2-Hacid_dh_C PF02826.14 KPI38083.1 - 0.018 14.1 0.1 0.2 10.7 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KPI38083.1 - 0.018 15.0 2.1 0.039 13.9 1.5 1.6 1 1 0 1 1 1 0 NADH(P)-binding NmrA PF05368.8 KPI38083.1 - 0.045 13.0 0.4 0.067 12.4 0.1 1.4 2 0 0 2 2 2 0 NmrA-like family 3HCDH_N PF02737.13 KPI38083.1 - 0.094 12.3 0.2 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Wax2_C PF12076.3 KPI38083.1 - 0.12 12.0 0.0 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 WAX2 C-terminal domain DUF1490 PF07371.7 KPI38083.1 - 0.21 11.5 5.7 0.17 11.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) Dynamin_N PF00350.18 KPI38085.1 - 1.2e-17 64.2 0.8 3.4e-17 62.7 0.0 2.2 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 KPI38085.1 - 4.3e-09 36.3 0.1 2.4e-08 33.9 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KPI38085.1 - 3.1e-07 30.0 1.1 2.7e-06 26.9 0.2 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 KPI38085.1 - 0.0029 17.9 0.0 0.0084 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KPI38085.1 - 0.013 16.0 0.1 0.77 10.2 0.1 2.9 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 KPI38085.1 - 0.074 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 KPI38085.1 - 0.089 12.2 0.0 18 4.8 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Epimerase PF01370.16 KPI38087.1 - 5.9e-09 35.7 0.0 4.2e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KPI38087.1 - 1.2e-07 31.2 0.0 1.9e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI38087.1 - 1.8e-06 28.0 0.0 6.1e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KPI38087.1 - 0.0003 21.0 0.0 0.001 19.3 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KPI38087.1 - 0.00098 18.1 0.1 0.0023 16.8 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 KPI38087.1 - 0.0022 17.0 0.1 0.0033 16.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 KPI38087.1 - 0.026 13.2 0.1 0.064 11.9 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family FAD_binding_3 PF01494.14 KPI38088.1 - 9.3e-83 278.2 0.0 1.2e-82 277.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KPI38088.1 - 5.1e-32 110.7 0.0 4.2e-31 107.8 0.0 2.3 3 0 0 3 3 3 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 KPI38088.1 - 0.00027 20.8 0.0 0.00058 19.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI38088.1 - 0.00054 19.1 0.0 0.0012 17.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KPI38088.1 - 0.00067 18.2 0.0 0.001 17.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 KPI38088.1 - 0.0014 17.6 0.0 0.0024 16.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KPI38088.1 - 0.002 17.0 0.1 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 KPI38088.1 - 0.0059 16.9 0.0 0.021 15.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI38088.1 - 0.011 14.5 0.1 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 KPI38088.1 - 0.011 15.7 0.1 0.058 13.4 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI38088.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KPI38088.1 - 0.11 11.5 0.1 0.2 10.6 0.1 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 KPI38088.1 - 0.12 12.4 0.0 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain p450 PF00067.17 KPI38089.1 - 1.1e-51 175.8 0.0 1.4e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TAXi_C PF14541.1 KPI38089.1 - 0.11 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DUF3500 PF12006.3 KPI38090.1 - 1.6e-90 303.2 0.0 6.6e-90 301.2 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3500) tRNA_int_end_N2 PF12928.2 KPI38092.1 - 2.5e-17 62.1 0.0 6.6e-17 60.7 0.0 1.8 2 0 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 KPI38092.1 - 0.00076 18.9 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain adh_short PF00106.20 KPI38093.1 - 5e-25 88.3 1.5 5.8e-17 62.1 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KPI38093.1 - 4.2e-17 62.3 0.8 3.9e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KPI38093.1 - 5.2e-12 46.0 0.8 3.8e-10 39.9 0.6 2.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase zf-C2H2_6 PF13912.1 KPI38093.1 - 0.00015 21.5 0.8 0.00039 20.2 0.6 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger NAD_binding_10 PF13460.1 KPI38093.1 - 0.00085 19.3 2.4 0.014 15.4 0.3 3.0 2 2 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KPI38093.1 - 0.0018 17.7 0.3 0.033 13.6 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family zf-met PF12874.2 KPI38093.1 - 0.077 13.2 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Polysacc_synt_2 PF02719.10 KPI38093.1 - 0.089 11.6 0.0 0.19 10.6 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein zf-C2H2_4 PF13894.1 KPI38093.1 - 0.16 12.4 0.2 0.37 11.2 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI38093.1 - 0.24 11.8 0.5 0.59 10.5 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Abhydrolase_6 PF12697.2 KPI38094.1 - 2.1e-13 50.6 2.2 2.1e-13 50.6 1.5 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI38094.1 - 4.1e-11 42.8 0.0 1.2e-10 41.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 KPI38094.1 - 7.1e-05 21.5 0.0 9.6e-05 21.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 KPI38094.1 - 0.00013 21.2 0.0 0.00025 20.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KPI38094.1 - 0.00059 19.4 1.8 0.0021 17.6 0.3 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KPI38094.1 - 0.047 13.2 0.2 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.7 KPI38094.1 - 0.11 10.9 0.0 0.24 9.8 0.0 1.4 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) MFS_1 PF07690.11 KPI38095.1 - 1e-30 106.7 29.9 1.2e-30 106.4 20.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Cu_amine_oxid PF01179.15 KPI38096.1 - 1.9e-99 333.2 1.7 2.4e-99 332.8 1.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 KPI38096.1 - 1.5e-10 40.8 0.1 4e-10 39.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 KPI38096.1 - 4.4e-05 23.4 0.0 0.0001 22.3 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain BCIP PF13862.1 KPI38098.1 - 3.2e-63 212.7 0.0 4e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein adh_short PF00106.20 KPI38099.1 - 8.5e-12 45.3 2.8 1.9e-10 40.8 1.4 3.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI38099.1 - 0.0042 16.8 0.0 0.024 14.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI38099.1 - 0.045 13.4 1.0 2.1 7.9 0.7 2.6 1 1 0 1 1 1 0 KR domain Amidase PF01425.16 KPI38100.1 - 2.8e-95 319.7 0.0 3.2e-95 319.5 0.0 1.0 1 0 0 1 1 1 1 Amidase Cpn60_TCP1 PF00118.19 KPI38101.1 - 5.2e-142 473.8 14.0 6e-142 473.6 9.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4112 PF13430.1 KPI38102.1 - 8.2e-30 102.8 0.3 1.3e-29 102.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) SET PF00856.23 KPI38103.1 - 4e-10 40.2 0.0 3.1e-09 37.3 0.0 2.3 1 1 0 1 1 1 1 SET domain TPR_8 PF13181.1 KPI38103.1 - 0.0095 15.6 0.1 0.038 13.7 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 KPI38103.1 - 0.027 14.3 1.0 0.11 12.4 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 KPI38103.1 - 9.5 6.3 7.3 0.5 10.3 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Het-C PF07217.6 KPI38104.1 - 3.8e-236 785.0 8.2 3.9e-218 725.5 0.3 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein Het-C PTRF_SDPR PF15237.1 KPI38105.1 - 0.015 14.7 1.5 0.016 14.6 1.0 1.0 1 0 0 1 1 1 0 PTRF/SDPR family DUF3774 PF12609.3 KPI38105.1 - 1.4 9.8 5.3 2.1 9.2 3.7 1.3 1 0 0 1 1 1 0 Wound-induced protein DUF1680 PF07944.7 KPI38106.1 - 4.2e-13 48.4 0.0 9.2e-13 47.2 0.0 1.4 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Prenyltrans_1 PF13243.1 KPI38106.1 - 0.11 12.5 0.1 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 Prenyltransferase-like GFA PF04828.9 KPI38107.1 - 1.2e-14 53.9 14.7 5e-08 32.7 0.5 3.6 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme NinF PF05810.7 KPI38107.1 - 0.073 12.8 0.7 8.2 6.3 0.0 2.6 2 0 0 2 2 2 0 NinF protein Rpr2 PF04032.11 KPI38107.1 - 7.5 6.4 8.5 1.8 8.4 1.2 2.8 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DNase_NucA_NucB PF14040.1 KPI38108.1 - 0.056 13.5 0.2 0.091 12.9 0.2 1.3 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB Sugar_tr PF00083.19 KPI38109.1 - 8e-84 281.7 34.6 1e-83 281.4 24.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI38109.1 - 7.5e-21 74.2 44.2 7.5e-21 74.2 30.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KPI38109.1 - 0.00013 20.4 31.3 0.0019 16.6 6.2 3.1 3 0 0 3 3 3 2 MFS/sugar transport protein U1snRNP70_N PF12220.3 KPI38110.1 - 3.4e-26 91.3 2.5 5.5e-26 90.7 1.8 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 KPI38110.1 - 1.7e-17 62.8 0.0 4.3e-17 61.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI38110.1 - 4.8e-12 45.6 0.0 8.8e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI38110.1 - 3.8e-07 29.8 0.0 6.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp PF00026.18 KPI38111.1 - 1.2e-56 192.3 1.8 1.4e-56 192.0 1.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KPI38111.1 - 3.8e-05 24.0 1.9 0.061 13.8 0.7 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 KPI38111.1 - 0.002 18.0 0.0 0.015 15.2 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Acetyltransf_1 PF00583.19 KPI38112.1 - 1.3e-05 25.1 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.1 KPI38112.1 - 0.018 14.7 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Acetyltransf_10 PF13673.1 KPI38112.1 - 0.026 14.6 0.0 0.078 13.0 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Pho86 PF11124.3 KPI38112.1 - 0.035 13.1 0.1 0.053 12.5 0.1 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Acetyltransf_9 PF13527.1 KPI38112.1 - 0.039 13.8 0.0 0.15 11.9 0.0 1.9 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KPI38112.1 - 0.071 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.19 KPI38113.1 - 3.2e-35 121.6 9.1 3.6e-35 121.4 6.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI38113.1 - 3.9e-11 42.2 22.8 5.2e-11 41.8 15.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily NMO PF03060.10 KPI38114.1 - 1.2e-58 198.8 0.1 1.4e-58 198.6 0.1 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KPI38114.1 - 8.1e-09 34.8 0.0 4.5e-06 25.8 0.0 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KPI38114.1 - 2.8e-06 26.4 0.1 4.2e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.9 KPI38114.1 - 0.0012 17.8 0.1 0.0018 17.2 0.1 1.3 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 KPI38114.1 - 0.015 14.5 0.1 0.042 13.1 0.0 1.6 1 1 0 1 1 1 0 Histidine biosynthesis protein DUF2910 PF11139.3 KPI38114.1 - 0.03 13.4 1.3 0.2 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) Pyr_redox_2 PF07992.9 KPI38115.1 - 9e-24 84.4 0.0 8.1e-17 61.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI38115.1 - 1.7e-12 47.5 0.0 4.6e-11 42.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI38115.1 - 0.01 15.8 0.2 1.7 8.6 0.1 3.4 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KPI38115.1 - 0.029 14.6 0.6 0.64 10.3 0.0 2.9 2 1 0 2 2 2 0 Putative NAD(P)-binding DUF4452 PF14618.1 KPI38117.1 - 1.1e-54 184.7 8.7 1.3e-54 184.4 6.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) WIYLD PF10440.4 KPI38118.1 - 0.1 12.5 1.0 0.24 11.3 0.1 2.1 2 1 1 3 3 3 0 Ubiquitin-binding WIYLD domain Skp1_POZ PF03931.10 KPI38119.1 - 2.7e-11 43.4 0.0 6.5e-11 42.1 0.0 1.6 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 KPI38119.1 - 0.058 13.3 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain Glyco_hydro_61 PF03443.9 KPI38120.1 - 4.1e-73 245.8 0.1 5.7e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 COesterase PF00135.23 KPI38121.1 - 2.5e-99 333.4 0.0 3.1e-99 333.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI38121.1 - 7.6e-08 32.1 0.2 2.8e-07 30.3 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chorion_2 PF03964.10 KPI38122.1 - 0.071 13.6 0.1 0.076 13.5 0.1 1.1 1 0 0 1 1 1 0 Chorion family 2 CM_2 PF01817.16 KPI38123.1 - 2.9e-08 33.6 0.0 0.0021 18.1 0.0 3.9 3 2 0 3 3 3 2 Chorismate mutase type II Zn_clus PF00172.13 KPI38125.1 - 0.076 12.9 5.4 0.13 12.2 3.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH PF00378.15 KPI38126.1 - 6.6e-41 140.0 0.3 9.3e-41 139.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KPI38126.1 - 0.0072 16.1 0.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 1 Peptidase family S49 Lung_7-TM_R PF06814.8 KPI38127.1 - 2.3e-65 220.4 15.0 2.8e-65 220.2 10.4 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PrgI PF12666.2 KPI38127.1 - 7.6 6.7 14.7 3.8 7.7 1.5 3.3 1 1 1 3 3 3 0 PrgI family protein Acyl-CoA_ox_N PF14749.1 KPI38128.1 - 2e-18 66.8 1.6 4.2e-18 65.8 1.1 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KPI38128.1 - 5.1e-09 35.5 0.2 4.3e-08 32.5 0.1 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KPI38128.1 - 0.00084 19.4 0.2 0.003 17.6 0.1 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain GPAT_N PF14829.1 KPI38128.1 - 0.12 12.1 0.0 0.39 10.4 0.0 1.8 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Aldedh PF00171.17 KPI38129.1 - 3.2e-125 418.1 0.0 3.5e-125 417.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KPI38129.1 - 2.3e-05 23.2 0.1 9.6e-05 21.2 0.0 1.9 2 1 0 2 2 2 1 Acyl-CoA reductase (LuxC) Sec7 PF01369.15 KPI38130.1 - 1.5e-59 200.8 0.0 2.6e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KPI38130.1 - 7.2e-21 74.3 0.0 1.4e-13 50.6 0.0 2.7 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal MutS_III PF05192.13 KPI38130.1 - 0.0084 15.9 0.0 5.1 6.8 0.0 2.8 2 1 1 3 3 3 2 MutS domain III ParA PF10609.4 KPI38131.1 - 1.1e-36 124.5 0.0 8e-36 121.7 0.0 2.1 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 KPI38131.1 - 5.5e-15 55.2 0.0 9.1e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KPI38131.1 - 1.1e-06 28.6 0.0 6.5e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KPI38131.1 - 2.7e-05 23.3 0.4 0.00082 18.5 0.1 2.6 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 KPI38131.1 - 0.0042 16.2 0.0 0.0087 15.1 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ AAA_30 PF13604.1 KPI38131.1 - 0.0063 16.1 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KPI38131.1 - 0.022 13.9 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 T2SE PF00437.15 KPI38131.1 - 0.034 13.0 0.1 0.5 9.2 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_26 PF13500.1 KPI38131.1 - 0.048 13.2 0.0 2.8 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KPI38131.1 - 0.073 12.4 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 KPI38131.1 - 0.12 11.4 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ChW PF07538.6 KPI38131.1 - 0.16 11.5 1.4 0.34 10.4 1.0 1.6 1 0 0 1 1 1 0 Clostridial hydrophobic W Zn_Tnp_IS1595 PF12760.2 KPI38131.1 - 4.3 7.2 5.9 0.29 10.9 0.2 1.9 2 0 0 2 2 1 0 Transposase zinc-ribbon domain TIP120 PF08623.5 KPI38132.1 - 2.9e-49 166.9 0.0 2.2e-47 160.8 0.0 3.7 4 1 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 KPI38132.1 - 2.9e-19 69.1 16.2 0.0013 18.9 0.0 8.6 5 3 3 8 8 8 6 HEAT repeats HEAT PF02985.17 KPI38132.1 - 4.5e-11 41.8 17.1 0.018 15.0 0.0 11.3 12 0 0 12 12 12 2 HEAT repeat HEAT_EZ PF13513.1 KPI38132.1 - 0.0022 18.4 32.4 0.66 10.5 0.0 10.6 11 2 1 12 12 12 3 HEAT-like repeat Ipi1_N PF12333.3 KPI38132.1 - 0.003 17.4 0.2 3.8 7.5 0.0 3.8 4 0 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.2 KPI38132.1 - 0.0084 15.9 1.6 6.3 6.6 0.0 5.7 7 1 1 8 8 8 1 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.3 KPI38132.1 - 0.015 15.2 1.0 95 2.8 0.0 5.3 6 0 0 6 6 6 0 Domain of unknown function (DUF3385) SEN1_N PF12726.2 KPI38132.1 - 0.2 9.6 1.0 0.42 8.6 0.0 2.0 3 0 0 3 3 3 0 SEN1 N terminal zf-C2H2_4 PF13894.1 KPI38133.1 - 0.19 12.1 1.7 0.38 11.2 0.5 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Pyr_redox_3 PF13738.1 KPI38134.1 - 1e-18 68.1 0.0 2.4e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI38134.1 - 2e-07 29.5 0.0 1.9e-06 26.3 0.0 2.3 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KPI38134.1 - 5.4e-06 25.5 0.0 0.0002 20.3 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 KPI38134.1 - 8e-06 25.9 0.1 0.0079 16.3 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 KPI38134.1 - 0.001 19.0 0.0 0.0037 17.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 KPI38134.1 - 0.051 12.7 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KPI38134.1 - 0.059 13.6 0.0 5.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.19 KPI38134.1 - 0.069 12.0 0.0 3.1 6.5 0.0 2.5 2 1 1 3 3 3 0 FAD dependent oxidoreductase Atg14 PF10186.4 KPI38135.1 - 1.5e-13 50.4 10.5 8e-07 28.2 0.0 2.2 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 KPI38135.1 - 0.016 13.6 1.8 0.03 12.8 1.2 1.3 1 0 0 1 1 1 0 AAA domain Cortex-I_coil PF09304.5 KPI38135.1 - 0.04 13.9 4.6 0.077 13.0 3.2 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil Snapin_Pallidin PF14712.1 KPI38135.1 - 0.15 12.3 6.8 0.32 11.3 4.7 1.5 1 0 0 1 1 1 0 Snapin/Pallidin Nnf1 PF03980.9 KPI38135.1 - 0.17 11.9 6.9 0.31 11.0 4.8 1.4 1 0 0 1 1 1 0 Nnf1 APG6 PF04111.7 KPI38135.1 - 0.42 9.5 2.6 2 7.4 1.8 1.9 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 KPI38135.1 - 0.89 9.9 2.7 4.4 7.6 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4482 PF14818.1 KPI38135.1 - 1 9.9 6.1 0.63 10.6 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) NYD-SP28_assoc PF14775.1 KPI38135.1 - 2.4 7.9 5.7 3.9 7.2 0.5 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain Pkinase PF00069.20 KPI38136.1 - 1.9e-18 66.5 0.0 4.8e-18 65.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI38136.1 - 1.1e-06 27.8 0.0 9e-06 24.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KPI38136.1 - 7.1e-05 22.6 0.0 0.03 14.0 0.0 3.0 2 0 0 2 2 2 2 Phosphotransferase enzyme family VWA_3 PF13768.1 KPI38136.1 - 0.0021 17.7 0.1 0.79 9.3 0.0 2.5 1 1 1 2 2 2 2 von Willebrand factor type A domain Fungal_trans PF04082.13 KPI38137.1 - 1e-40 139.2 6.3 1.9e-40 138.3 4.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KPI38137.1 - 1.3e-10 40.9 11.5 4.1e-06 26.8 1.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI38137.1 - 4.3e-07 29.8 12.3 0.00039 20.5 0.8 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger ThiF PF00899.16 KPI38138.1 - 1.5e-42 144.6 0.1 3.5e-42 143.4 0.0 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KPI38138.1 - 1.8e-31 107.4 0.3 3.3e-31 106.6 0.2 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 KPI38138.1 - 1e-19 70.4 2.5 1.6e-19 69.8 0.7 2.1 2 1 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 KPI38138.1 - 1.3e-19 69.2 0.4 2.3e-19 68.4 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 KPI38138.1 - 0.0014 18.8 0.0 0.0055 16.9 0.0 2.0 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.22 KPI38138.1 - 0.0051 17.1 0.1 1.1 9.7 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KPI38138.1 - 0.0059 16.7 0.1 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF2443 PF10398.4 KPI38138.1 - 0.026 14.2 0.1 0.14 11.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) NAD_binding_10 PF13460.1 KPI38139.1 - 4.9e-20 72.3 0.1 7.6e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KPI38139.1 - 3.5e-07 29.7 0.0 6.7e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KPI38139.1 - 0.00028 20.4 0.0 0.0032 16.9 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KPI38139.1 - 0.03 13.9 0.1 0.13 11.8 0.0 2.1 1 1 0 1 1 1 0 KR domain adh_short PF00106.20 KPI38139.1 - 0.037 13.9 0.1 0.15 12.0 0.0 1.9 1 1 1 2 2 2 0 short chain dehydrogenase PhnG PF06754.7 KPI38139.1 - 0.1 12.2 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG Ribosomal_L18e PF00828.14 KPI38140.1 - 4.1e-06 27.1 1.3 4.1e-06 27.1 0.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Oxidored_FMN PF00724.15 KPI38141.1 - 3.7e-91 305.6 0.0 4.7e-91 305.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 KPI38141.1 - 0.079 12.2 0.1 3.5 6.8 0.0 2.6 1 1 2 3 3 3 0 Xylose isomerase-like TIM barrel DLH PF01738.13 KPI38143.1 - 6.4e-30 104.0 0.0 8.4e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KPI38143.1 - 0.00028 20.6 0.0 0.0004 20.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI38143.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Tub_2 PF04525.7 KPI38144.1 - 3.5e-18 65.6 0.0 3.9e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 ALG3 PF05208.8 KPI38145.1 - 8.8e-115 383.8 10.5 1e-114 383.6 7.3 1.0 1 0 0 1 1 1 1 ALG3 protein Amidohydro_1 PF01979.15 KPI38146.1 - 5.4e-32 111.7 0.0 6.6e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KPI38146.1 - 1.2e-18 68.1 0.0 6.2e-17 62.5 0.0 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KPI38146.1 - 5.5e-12 45.3 0.0 1.6e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KPI38146.1 - 3.9e-11 42.8 0.2 2.4e-09 36.9 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Kelch_3 PF13415.1 KPI38147.1 - 1.1e-24 85.9 0.7 4e-06 26.8 0.0 5.1 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.1 KPI38147.1 - 5.9e-21 73.9 0.8 2.1e-11 43.4 0.1 3.7 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.1 KPI38147.1 - 4.9e-08 32.8 1.1 0.088 13.0 0.0 4.2 3 1 1 4 4 4 2 Kelch motif Kelch_5 PF13854.1 KPI38147.1 - 1.1e-06 28.4 0.0 0.018 14.9 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 KPI38147.1 - 7.1e-06 25.4 0.0 0.13 11.8 0.0 4.4 4 2 0 4 4 4 2 Kelch motif DIOX_N PF14226.1 KPI38148.1 - 4.3e-29 101.3 0.0 9e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI38148.1 - 2.1e-23 82.4 0.1 1.5e-22 79.7 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily GFO_IDH_MocA PF01408.17 KPI38149.1 - 1e-20 74.4 0.0 1.8e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KPI38149.1 - 1.3e-06 28.2 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF1168 PF06658.7 KPI38150.1 - 0.021 14.3 0.5 0.03 13.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF1796 PF08795.5 KPI38150.1 - 0.033 13.8 0.4 0.047 13.3 0.3 1.2 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) ERCC4 PF02732.10 KPI38151.1 - 3.2e-07 30.2 0.0 9.7e-07 28.6 0.0 1.9 1 1 0 1 1 1 1 ERCC4 domain Borrelia_P83 PF05262.6 KPI38151.1 - 0.05 11.8 11.8 0.085 11.1 8.2 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.7 KPI38151.1 - 0.76 9.6 9.5 2 8.2 6.6 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.9 KPI38152.1 - 2.7e-12 47.0 3.3 0.036 13.8 0.0 5.9 3 2 2 6 6 6 3 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KPI38152.1 - 7.5e-09 35.4 14.9 1.1 10.0 0.0 9.7 7 2 3 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.1 KPI38152.1 - 1.5e-07 31.1 1.2 1.7 8.6 0.1 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KPI38152.1 - 2.5e-07 30.9 0.5 0.19 12.0 0.0 5.7 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KPI38152.1 - 0.0015 19.1 17.6 0.046 14.4 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 KPI38152.1 - 0.0016 18.2 2.1 17 5.1 0.0 5.9 6 2 0 6 6 6 0 Mad3/BUB1 homology region 1 TPR_11 PF13414.1 KPI38152.1 - 0.002 17.7 10.0 1.8 8.2 0.0 6.0 5 1 1 6 6 6 1 TPR repeat TPR_17 PF13431.1 KPI38152.1 - 0.0021 18.1 0.6 3.5 8.0 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat NRDE-2 PF08424.5 KPI38152.1 - 0.0029 16.5 7.4 0.78 8.5 0.1 5.1 2 2 3 5 5 5 2 NRDE-2, necessary for RNA interference PPR_3 PF13812.1 KPI38152.1 - 0.038 14.2 0.2 1.3 9.5 0.0 3.7 2 0 0 2 2 2 0 Pentatricopeptide repeat domain TPR_2 PF07719.12 KPI38152.1 - 0.36 10.8 12.6 7 6.8 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 KPI38152.1 - 2.3 8.8 9.6 0.57 10.7 0.2 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat HAT PF02184.11 KPI38152.1 - 8.6 6.2 16.0 9.5 6.0 0.0 6.5 8 0 0 8 8 7 0 HAT (Half-A-TPR) repeat Abhydrolase_2 PF02230.11 KPI38153.1 - 1.3e-19 70.5 6.4 2e-07 30.6 0.0 3.9 2 1 1 3 3 3 3 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KPI38153.1 - 3.1e-08 33.8 0.0 4.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI38153.1 - 1.6e-06 27.9 0.0 4.1e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI38153.1 - 3.1e-06 26.5 0.0 5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIP PF03583.9 KPI38153.1 - 6e-05 22.3 0.0 8.8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Secretory lipase DLH PF01738.13 KPI38153.1 - 0.089 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Fungal_trans_2 PF11951.3 KPI38154.1 - 9.4e-35 119.9 1.7 1.2e-34 119.5 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PaaB PF06243.6 KPI38154.1 - 0.022 14.8 1.6 0.21 11.7 0.1 2.4 2 0 0 2 2 2 0 Phenylacetic acid degradation B DUF3453 PF11935.3 KPI38154.1 - 0.05 13.0 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) Sec2p PF06428.6 KPI38155.1 - 4e-09 36.2 7.7 4e-09 36.2 5.3 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p MbeB_N PF04837.7 KPI38155.1 - 0.028 14.4 0.9 0.099 12.7 0.6 2.0 1 0 0 1 1 1 0 MbeB-like, N-term conserved region Rabaptin PF03528.10 KPI38155.1 - 0.043 13.7 1.3 0.043 13.7 0.9 2.4 2 0 0 2 2 2 0 Rabaptin AATF-Che1 PF13339.1 KPI38155.1 - 0.13 12.4 6.0 3.5 7.7 0.7 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor ATG16 PF08614.6 KPI38155.1 - 0.13 12.0 14.9 0.12 12.2 3.3 2.1 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) IncA PF04156.9 KPI38155.1 - 0.19 11.2 10.2 1.5 8.3 0.1 2.1 2 0 0 2 2 2 0 IncA protein Laminin_II PF06009.7 KPI38155.1 - 0.47 10.1 4.5 1 9.1 0.5 2.1 2 0 0 2 2 2 0 Laminin Domain II PAT1 PF09770.4 KPI38155.1 - 1 7.4 15.2 1.3 7.1 10.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 KAR9 PF08580.5 KPI38155.1 - 3.7 5.6 6.7 5.6 5.1 4.7 1.4 1 1 0 1 1 1 0 Yeast cortical protein KAR9 DUF4140 PF13600.1 KPI38155.1 - 4.3 7.8 16.3 1.3 9.5 0.2 3.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Aldo_ket_red PF00248.16 KPI38156.1 - 1.4e-63 214.3 0.0 1.7e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.23 KPI38157.1 - 1.1e-57 195.3 0.0 1.4e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI38157.1 - 2.8e-11 44.1 0.1 7.5e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.1 KPI38158.1 - 2.8e-24 86.2 0.0 3.2e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI38158.1 - 2.9e-19 69.5 0.6 3.6e-19 69.2 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI38158.1 - 5.9e-11 42.3 0.6 1.1e-10 41.4 0.4 1.4 1 1 0 1 1 1 1 KR domain GFA PF04828.9 KPI38159.1 - 8.8e-06 25.5 0.0 2.3e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 KPI38159.1 - 0.032 13.9 0.1 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Nudix N-terminal DUF2986 PF11661.3 KPI38159.1 - 0.4 11.0 3.6 0.34 11.2 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2986) DUF4544 PF15077.1 KPI38159.1 - 6 6.3 10.8 7.9 5.9 0.3 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4544) FAD_binding_3 PF01494.14 KPI38160.1 - 3.1e-07 29.7 0.2 2.3e-06 26.9 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KPI38160.1 - 0.00059 19.8 0.1 0.0019 18.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI38160.1 - 0.0019 17.1 0.0 0.0088 14.9 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KPI38160.1 - 0.0036 16.9 0.1 0.0058 16.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 KPI38160.1 - 0.0048 17.2 0.1 0.027 14.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KPI38160.1 - 0.007 15.4 0.1 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI38160.1 - 0.13 11.0 0.7 0.2 10.4 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain PEMT PF04191.8 KPI38161.1 - 5.5e-56 187.1 8.4 1.6e-34 118.1 0.6 3.1 3 0 0 3 3 3 2 Phospholipid methyltransferase ICMT PF04140.9 KPI38161.1 - 0.15 12.2 4.1 0.14 12.3 0.2 2.8 3 1 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PalH PF08733.5 KPI38162.1 - 1.3e-95 320.2 0.0 2.6e-95 319.2 0.0 1.5 1 1 0 1 1 1 1 PalH/RIM21 p450 PF00067.17 KPI38164.1 - 1.3e-53 182.1 0.0 3.3e-53 180.8 0.0 1.7 1 1 1 2 2 2 1 Cytochrome P450 NAD_binding_10 PF13460.1 KPI38165.1 - 0.00032 20.7 0.0 0.0065 16.4 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding Pyr_redox_3 PF13738.1 KPI38166.1 - 4.8e-28 98.6 0.0 8.6e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI38166.1 - 2.5e-17 62.2 0.0 4e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KPI38166.1 - 1.7e-12 47.6 0.0 3.6e-09 36.7 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI38166.1 - 3.5e-11 42.5 0.0 1.1e-08 34.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KPI38166.1 - 3.6e-11 42.9 0.0 1e-09 38.2 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KPI38166.1 - 8.9e-09 35.6 0.1 0.0041 17.5 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI38166.1 - 5.2e-07 28.9 0.1 2.2e-05 23.5 0.0 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 KPI38166.1 - 2.6e-06 26.5 0.1 0.08 11.7 0.1 3.9 4 0 0 4 4 4 1 Glucose inhibited division protein A DAO PF01266.19 KPI38166.1 - 2.6e-06 26.6 0.3 0.0012 17.8 0.1 3.6 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KPI38166.1 - 1.1e-05 25.2 0.1 0.23 11.2 0.1 4.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KPI38166.1 - 2.7e-05 23.2 0.1 6.5e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KPI38166.1 - 3.6e-05 22.9 0.4 0.0004 19.5 0.1 2.4 3 0 0 3 3 3 1 Thi4 family FAD_oxidored PF12831.2 KPI38166.1 - 0.00028 20.0 0.3 0.0005 19.2 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 KPI38166.1 - 0.0011 19.0 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 KPI38166.1 - 0.005 16.9 0.6 5.7 7.0 0.1 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 KPI38166.1 - 0.0056 15.2 1.0 1.1 7.6 0.1 3.5 4 0 0 4 4 4 1 HI0933-like protein CPSase_L_chain PF00289.17 KPI38166.1 - 0.1 12.7 0.0 8.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain 2-Hacid_dh_C PF02826.14 KPI38166.1 - 0.11 11.6 0.0 0.44 9.6 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding PF02629.14 KPI38166.1 - 0.13 12.7 0.2 15 6.1 0.1 2.3 2 0 0 2 2 2 0 CoA binding domain AlaDh_PNT_C PF01262.16 KPI38166.1 - 0.17 11.4 0.9 2.9 7.4 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 KPI38166.1 - 2.6 7.0 4.6 0.25 10.3 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain Solute_trans_a PF03619.11 KPI38167.1 - 2.4e-29 102.5 12.1 3.4e-29 102.0 8.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF2919 PF11143.3 KPI38167.1 - 0.013 15.3 14.6 0.08 12.7 0.3 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2919) Git3_C PF11970.3 KPI38167.1 - 0.25 11.1 5.8 0.64 9.8 1.4 2.6 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Zn_clus PF00172.13 KPI38169.1 - 1.1e-07 31.5 10.6 1.7e-07 31.0 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.23 KPI38170.1 - 4.6e-28 97.5 0.0 6.6e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF1436 PF07262.6 KPI38170.1 - 0.13 11.7 0.2 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1436) MFS_1 PF07690.11 KPI38171.1 - 5.6e-28 97.6 31.1 9.1e-22 77.2 14.9 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily CD34_antigen PF06365.7 KPI38171.1 - 0.0037 16.9 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF3176 PF11374.3 KPI38172.1 - 1.3e-26 92.6 0.4 2.7e-26 91.5 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) RRM_1 PF00076.17 KPI38173.1 - 9.1e-28 95.7 0.2 9.8e-13 47.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI38173.1 - 5.3e-16 58.3 0.0 1.2e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI38173.1 - 6.1e-15 54.8 0.0 8.2e-09 35.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.1 KPI38173.1 - 0.0069 15.9 0.0 0.11 12.0 0.0 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF4523) DUF1866 PF08952.6 KPI38173.1 - 0.022 14.3 0.0 0.059 12.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) RRM_3 PF08777.6 KPI38173.1 - 0.037 13.8 0.8 0.15 11.9 0.6 2.0 1 1 0 1 1 1 0 RNA binding motif PLAC8 PF04749.12 KPI38174.1 - 7.1e-09 36.1 0.6 1.1e-08 35.5 0.4 1.3 1 0 0 1 1 1 1 PLAC8 family BTB PF00651.26 KPI38175.1 - 0.019 14.9 0.0 0.059 13.3 0.0 1.9 1 1 0 1 1 1 0 BTB/POZ domain COesterase PF00135.23 KPI38176.1 - 1.8e-86 290.9 0.0 2.3e-86 290.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI38176.1 - 1.2e-07 31.5 0.0 3.3e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI38176.1 - 0.02 14.6 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1749 PF08538.5 KPI38176.1 - 0.049 12.5 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Alpha_kinase PF02816.13 KPI38177.1 - 5.6e-42 143.5 0.0 6.7e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Citrate_synt PF00285.16 KPI38178.1 - 1e-18 67.2 0.0 4.1e-16 58.6 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 KPI38178.1 - 2.4e-17 63.2 0.0 7.7e-17 61.5 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KPI38178.1 - 3.5e-15 55.9 0.0 6.3e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KPI38178.1 - 4.1e-05 23.2 0.0 0.00025 20.6 0.0 2.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain MFS_1 PF07690.11 KPI38179.1 - 2.3e-31 108.7 34.2 3.7e-31 108.1 23.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily CDC27 PF09507.5 KPI38180.1 - 0.63 9.1 20.7 0.75 8.9 14.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ATP-synt_D PF01813.12 KPI38181.1 - 1.5e-65 220.4 4.7 1.9e-65 220.1 3.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Cob_adeno_trans PF01923.13 KPI38181.1 - 0.025 14.3 1.0 0.079 12.7 0.0 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Syntaxin_2 PF14523.1 KPI38181.1 - 0.74 9.8 4.7 14 5.7 0.1 2.7 2 1 0 2 2 2 0 Syntaxin-like protein Nup54 PF13874.1 KPI38181.1 - 0.82 9.3 5.5 3.1 7.4 0.2 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 GvpL_GvpF PF06386.6 KPI38181.1 - 1.4 8.4 5.8 4.3 6.8 1.2 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DUF2392 PF10288.4 KPI38182.1 - 4e-19 68.9 0.0 7.7e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) Coat_F PF07875.7 KPI38182.1 - 0.029 14.5 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 Coat F domain Usp PF00582.21 KPI38182.1 - 0.12 12.5 0.1 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 Universal stress protein family Aldo_ket_red PF00248.16 KPI38183.1 - 1.2e-61 208.0 0.1 1.3e-61 207.8 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MIP-T3 PF10243.4 KPI38184.1 - 3.1e-08 32.5 46.9 4.6e-08 32.0 32.5 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CDC45 PF02724.9 KPI38184.1 - 5.7e-05 21.3 27.5 8.1e-05 20.8 19.1 1.3 1 0 0 1 1 1 1 CDC45-like protein SAPS PF04499.10 KPI38184.1 - 0.0013 17.5 17.9 0.0018 16.9 12.4 1.4 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein DUF2413 PF10310.4 KPI38184.1 - 0.0013 17.6 30.4 0.0013 17.6 21.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2413) GAGA_bind PF06217.7 KPI38184.1 - 0.0035 17.3 28.4 0.0035 17.3 19.7 1.6 2 0 0 2 2 2 1 GAGA binding protein-like family Mem_trans PF03547.13 KPI38184.1 - 0.017 13.4 4.4 0.024 12.9 3.0 1.2 1 0 0 1 1 1 0 Membrane transport protein Ndc1_Nup PF09531.5 KPI38184.1 - 0.31 9.3 9.5 0.38 9.1 6.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2201_N PF13203.1 KPI38184.1 - 0.39 9.8 25.3 0.036 13.2 14.5 1.6 2 0 0 2 2 2 0 Putative metallopeptidase domain Herpes_env PF01673.13 KPI38184.1 - 0.79 8.2 11.8 1.1 7.6 8.2 1.3 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF4045 PF13254.1 KPI38184.1 - 1.8 7.7 31.8 2.3 7.3 19.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) CENP-T PF15511.1 KPI38184.1 - 1.9 7.6 34.4 0.23 10.6 21.1 1.4 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T SprA-related PF12118.3 KPI38184.1 - 2.2 7.5 46.0 0.22 10.8 28.5 1.8 2 0 0 2 2 2 0 SprA-related family Daxx PF03344.10 KPI38184.1 - 3.1 6.1 48.6 4.7 5.5 33.7 1.3 1 0 0 1 1 1 0 Daxx Family CRT10 PF08728.5 KPI38184.1 - 4.6 5.1 13.0 5.4 4.8 9.0 1.1 1 0 0 1 1 1 0 CRT10 DUF2151 PF10221.4 KPI38184.1 - 6.6 4.7 24.6 7.7 4.5 17.0 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Hid1 PF12722.2 KPI38184.1 - 9.6 3.7 28.3 13 3.3 19.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Hexokinase_1 PF00349.16 KPI38185.1 - 4e-24 85.0 0.0 7e-23 81.0 0.0 2.1 1 1 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 KPI38185.1 - 8.6e-24 84.0 0.0 2.2e-19 69.6 0.0 2.2 2 0 0 2 2 2 2 Hexokinase K_oxygenase PF13434.1 KPI38185.1 - 0.015 14.2 0.0 0.022 13.7 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Peptidase_M20 PF01546.23 KPI38186.1 - 3.4e-20 72.3 0.0 4.7e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KPI38186.1 - 6.6e-13 48.3 0.0 1.4e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.11 KPI38187.1 - 4.4e-30 104.5 24.6 6e-30 104.1 17.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily S-layer PF07752.6 KPI38187.1 - 0.093 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 S-layer protein DUF308 PF03729.8 KPI38187.1 - 0.16 12.0 15.2 0.14 12.1 5.4 3.4 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) WD40 PF00400.27 KPI38189.1 - 2.9e-21 74.5 8.2 1.5e-09 37.3 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KPI38189.1 - 2.8e-17 62.3 0.0 1.1e-16 60.5 0.0 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 KPI38189.1 - 0.0014 16.9 0.9 0.0014 16.9 0.6 1.5 2 0 0 2 2 2 1 Nucleoporin Nup120/160 ProRS-C_1 PF09180.6 KPI38190.1 - 1.2e-21 76.4 1.8 2.7e-21 75.2 1.2 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 KPI38190.1 - 1e-10 41.4 0.0 6.3e-10 38.8 0.0 2.3 3 0 0 3 3 3 1 Anticodon binding domain DUF566 PF04484.7 KPI38191.1 - 0.29 10.6 2.8 0.41 10.1 1.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Spb1_C PF07780.7 KPI38192.1 - 1.2e-68 230.8 26.9 1.2e-68 230.8 18.6 4.2 3 2 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 KPI38192.1 - 9.2e-55 185.4 0.0 1.8e-54 184.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 KPI38192.1 - 8.7e-53 178.0 16.5 8.7e-53 178.0 11.4 4.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3381) MFS_1 PF07690.11 KPI38193.1 - 1.3e-26 93.2 18.9 1.3e-26 93.2 13.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI38193.1 - 1.2e-17 63.6 20.0 9e-16 57.4 13.8 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter Arm PF00514.18 KPI38194.1 - 8.4e-63 206.2 29.9 1.9e-12 46.5 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KPI38194.1 - 2e-19 69.6 11.6 0.00069 19.8 0.2 7.5 2 1 4 6 6 6 5 HEAT repeats HEAT_EZ PF13513.1 KPI38194.1 - 1.7e-15 56.9 11.3 0.0022 18.4 0.1 7.4 6 2 2 8 8 8 5 HEAT-like repeat HEAT PF02985.17 KPI38194.1 - 1.8e-15 55.5 18.8 0.042 13.9 0.0 9.3 11 0 0 11 11 10 6 HEAT repeat Arm_2 PF04826.8 KPI38194.1 - 4.2e-08 32.6 5.6 0.027 13.5 0.1 3.5 2 1 1 3 3 3 3 Armadillo-like Adaptin_N PF01602.15 KPI38194.1 - 8.1e-08 31.0 10.0 0.00026 19.4 2.4 3.0 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_N PF03224.9 KPI38194.1 - 9.9e-07 28.1 1.7 0.029 13.4 0.3 3.0 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.7 KPI38194.1 - 2e-06 26.0 2.7 2.5e-06 25.7 0.9 1.8 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) DUF1981 PF09324.5 KPI38194.1 - 0.029 13.8 0.1 1.2 8.6 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF1981) DUF908 PF06012.7 KPI38194.1 - 0.043 13.1 5.9 0.45 9.7 0.1 3.1 2 1 1 3 3 3 0 Domain of Unknown Function (DUF908) HEAT_PBS PF03130.11 KPI38194.1 - 0.047 14.1 10.6 23 5.8 0.1 6.9 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.4 KPI38194.1 - 0.16 11.7 2.1 4.8 6.9 0.0 3.4 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Lipase_GDSL PF00657.17 KPI38195.1 - 4.5e-14 52.8 0.2 6.5e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KPI38195.1 - 5.4e-13 49.4 0.1 7.4e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KPI38195.1 - 0.007 16.1 0.5 0.05 13.3 0.0 2.2 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family DUF2419 PF10343.4 KPI38196.1 - 2.4e-63 214.0 0.0 1.6e-62 211.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2419) TFIIA PF03153.8 KPI38196.1 - 5.4 6.7 8.6 7.3 6.3 5.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Heme_oxygenase PF01126.15 KPI38197.1 - 0.00019 21.0 0.0 0.00043 19.9 0.0 1.6 1 1 0 1 1 1 1 Heme oxygenase DUF3488 PF11992.3 KPI38198.1 - 0.14 10.7 4.9 0.26 9.8 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) zf-HIT PF04438.11 KPI38199.1 - 2.8e-11 42.8 6.7 4.5e-11 42.1 4.7 1.3 1 0 0 1 1 1 1 HIT zinc finger Tnp_zf-ribbon_2 PF13842.1 KPI38199.1 - 2.8 8.3 10.7 6.4 7.2 7.4 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Isochorismatase PF00857.15 KPI38200.1 - 3e-24 85.8 0.0 4.7e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family MFS_1 PF07690.11 KPI38201.1 - 1.3e-24 86.6 53.8 7.9e-16 57.7 19.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KPI38201.1 - 0.018 15.0 0.5 0.018 15.0 0.4 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) HET PF06985.6 KPI38203.1 - 2.2e-24 86.1 0.1 4.3e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GFA PF04828.9 KPI38203.1 - 5.2e-10 39.1 0.2 1.2e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ATP-grasp_2 PF08442.5 KPI38204.1 - 9.7e-07 28.3 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain MRI PF15325.1 KPI38206.1 - 4 8.4 7.4 5.9 7.9 5.1 1.2 1 0 0 1 1 1 0 Modulator of retrovirus infection TLP-20 PF06088.6 KPI38207.1 - 0.26 10.9 3.6 0.42 10.2 2.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CDC45 PF02724.9 KPI38207.1 - 0.3 9.0 5.7 0.35 8.8 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Mob1_phocein PF03637.12 KPI38208.1 - 0.09 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Mob1/phocein family CBS PF00571.23 KPI38209.1 - 5.8e-19 67.6 10.3 2.7e-10 39.8 0.1 4.3 4 0 0 4 4 4 3 CBS domain DIOX_N PF14226.1 KPI38210.1 - 8.1e-30 103.7 0.1 1.4e-29 102.9 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI38210.1 - 4.7e-26 90.9 0.0 1e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.13 KPI38211.1 - 2.7e-08 33.5 14.0 4.8e-08 32.7 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KPI38211.1 - 1.5e-06 27.3 0.3 2e-06 26.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TFIIA_gamma_C PF02751.9 KPI38212.1 - 4.3e-24 84.0 2.0 5.8e-24 83.6 1.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KPI38212.1 - 1.9e-22 78.5 0.2 2.7e-22 78.0 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TRI12 PF06609.8 KPI38213.1 - 7.4e-61 206.0 14.0 1.2e-60 205.3 9.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI38213.1 - 1e-21 77.0 17.4 1e-21 77.0 12.1 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI38213.1 - 8.7e-14 50.9 11.7 8.7e-14 50.9 8.1 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter Wzz PF02706.10 KPI38213.1 - 0.12 12.1 0.9 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Chain length determinant protein ABC2_membrane PF01061.19 KPI38214.1 - 1e-53 181.6 55.8 4.9e-34 117.3 14.1 3.8 4 0 0 4 4 4 3 ABC-2 type transporter ABC_tran PF00005.22 KPI38214.1 - 2.9e-37 128.0 0.2 1.8e-19 70.3 0.0 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 KPI38214.1 - 3.7e-25 87.5 9.7 4.4e-22 77.7 0.0 3.5 3 1 1 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KPI38214.1 - 1.3e-14 54.0 0.0 2.9e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KPI38214.1 - 2.3e-06 27.1 0.2 0.015 14.7 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KPI38214.1 - 0.00015 21.8 0.3 0.013 15.4 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KPI38214.1 - 0.00038 20.6 1.5 0.042 13.9 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KPI38214.1 - 0.0017 18.3 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KPI38214.1 - 0.0025 17.7 0.4 0.021 14.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KPI38214.1 - 0.0028 17.1 0.5 1.1 8.7 0.1 2.9 2 1 1 3 3 3 1 FtsK/SpoIIIE family DUF258 PF03193.11 KPI38214.1 - 0.0031 16.7 1.4 0.0034 16.5 0.1 1.7 2 0 0 2 2 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KPI38214.1 - 0.011 15.2 0.9 0.011 15.2 0.6 2.8 3 0 0 3 3 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KPI38214.1 - 0.016 15.1 0.1 0.84 9.6 0.1 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase NACHT PF05729.7 KPI38214.1 - 0.018 14.7 2.5 2.2 7.9 0.4 2.6 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 KPI38214.1 - 0.021 15.0 0.7 2.1 8.5 0.3 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KPI38214.1 - 0.021 14.6 4.7 0.29 11.0 0.1 3.1 3 0 0 3 3 2 0 AAA domain T2SE PF00437.15 KPI38214.1 - 0.029 13.2 1.6 3.2 6.5 0.0 2.6 3 0 0 3 3 2 0 Type II/IV secretion system protein SbcCD_C PF13558.1 KPI38214.1 - 0.054 13.4 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 1 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 KPI38214.1 - 0.056 12.9 2.5 0.22 11.0 0.3 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.13 KPI38214.1 - 0.057 12.9 0.1 6.6 6.2 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KPI38214.1 - 0.063 13.5 0.2 0.69 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KPI38214.1 - 0.074 12.6 4.8 0.6 9.7 0.8 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 KPI38214.1 - 0.082 12.1 0.2 9 5.4 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 KPI38214.1 - 0.086 11.9 0.3 0.85 8.6 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin Miro PF08477.8 KPI38214.1 - 0.13 12.7 0.2 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 KPI38214.1 - 0.15 12.9 0.2 1.4 9.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KPI38214.1 - 0.17 11.3 6.7 0.14 11.6 0.8 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 KPI38214.1 - 0.21 11.1 1.0 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 KPI38214.1 - 0.32 10.7 3.6 16 5.3 0.1 2.9 2 0 0 2 2 2 0 Part of AAA domain AAA_23 PF13476.1 KPI38214.1 - 0.41 10.9 0.0 1 9.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KPI38214.1 - 0.76 8.7 0.0 4.3 6.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.13 KPI38214.1 - 1.1 8.2 1.0 3.5 6.5 0.1 2.0 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.10 KPI38214.1 - 1.8 8.2 3.2 96 2.6 0.5 3.3 3 0 0 3 3 3 0 NTPase AAA_24 PF13479.1 KPI38214.1 - 7.7 6.0 6.1 12 5.4 0.9 2.6 2 0 0 2 2 2 0 AAA domain Mito_carr PF00153.22 KPI38215.1 - 7.3e-60 198.6 6.7 4.4e-21 74.3 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.17 KPI38216.1 - 2.6e-31 108.2 0.1 3.2e-31 107.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KPI38216.1 - 2.7e-20 73.0 0.1 9e-20 71.3 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KPI38216.1 - 1.3e-06 27.7 0.1 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KPI38216.1 - 7.8e-06 25.1 0.2 1e-05 24.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KPI38216.1 - 0.055 13.4 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DLIC PF05783.6 KPI38216.1 - 0.058 12.0 0.1 4.7 5.7 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.15 KPI38216.1 - 0.091 11.4 0.6 0.15 10.6 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit Hemerythrin PF01814.18 KPI38217.1 - 0.024 14.7 0.4 0.039 14.1 0.3 1.4 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Cep57_MT_bd PF06657.8 KPI38217.1 - 0.15 12.0 2.8 0.22 11.5 0.4 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 HET PF06985.6 KPI38219.1 - 1e-29 103.4 1.0 1.9e-29 102.6 0.7 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PP2C PF00481.16 KPI38220.1 - 1.7e-64 217.6 0.8 1.6e-53 181.7 0.6 3.1 1 1 1 2 2 2 2 Protein phosphatase 2C ApbA PF02558.11 KPI38221.1 - 4e-25 88.0 0.0 6.5e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KPI38221.1 - 7.2e-24 84.1 0.1 1e-23 83.6 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DAO PF01266.19 KPI38221.1 - 0.08 11.8 0.3 0.14 11.0 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Saccharop_dh PF03435.13 KPI38221.1 - 0.09 11.7 0.2 0.28 10.1 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase DUF2419 PF10343.4 KPI38222.1 - 1.4e-23 83.6 0.0 1.8e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) DUF3315 PF11776.3 KPI38222.1 - 3.2 7.3 5.5 0.4 10.2 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3315) zf-RING_2 PF13639.1 KPI38223.1 - 0.0057 16.4 11.7 0.0057 16.4 8.1 2.2 1 1 1 2 2 2 1 Ring finger domain Trypan_PARP PF05887.6 KPI38223.1 - 0.013 15.2 5.0 0.031 14.1 3.4 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-Sec23_Sec24 PF04810.10 KPI38223.1 - 0.069 12.7 2.0 9.4 5.8 0.3 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DUF4485 PF14846.1 KPI38224.1 - 0.24 11.1 1.4 0.43 10.3 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) 3Beta_HSD PF01073.14 KPI38225.1 - 2.8e-18 65.5 0.0 7.9e-18 64.1 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KPI38225.1 - 5.5e-15 55.4 0.0 1.3e-14 54.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KPI38225.1 - 1.4e-11 43.8 0.0 2.3e-10 39.8 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.20 KPI38225.1 - 4.7e-05 23.3 0.2 0.00014 21.8 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KPI38225.1 - 0.00012 22.1 0.0 0.00075 19.5 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KPI38225.1 - 0.00027 20.6 0.6 0.0023 17.6 0.4 2.0 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 KPI38225.1 - 0.00067 18.6 0.0 0.0038 16.1 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KPI38225.1 - 0.0014 17.6 0.0 0.0047 15.8 0.0 1.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein eIF-1a PF01176.14 KPI38226.1 - 1.3e-12 46.9 0.0 2.1e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Amidase PF01425.16 KPI38227.1 - 3.3e-90 303.0 0.0 4.6e-90 302.5 0.0 1.2 1 0 0 1 1 1 1 Amidase zf-RING_5 PF14634.1 KPI38228.1 - 3e-05 23.6 0.9 4.9e-05 22.9 0.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KPI38228.1 - 5.5e-05 23.1 0.6 0.00012 22.0 0.4 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI38228.1 - 0.0039 16.8 0.7 0.0072 15.9 0.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KPI38228.1 - 0.0045 16.7 1.0 0.0078 16.0 0.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KPI38228.1 - 0.0088 15.7 2.5 0.022 14.4 1.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KPI38228.1 - 0.043 13.7 0.4 0.52 10.2 0.1 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FYVE PF01363.16 KPI38228.1 - 0.073 12.9 2.6 0.15 11.9 1.8 1.5 1 1 0 1 1 1 0 FYVE zinc finger zf-UBP PF02148.14 KPI38228.1 - 0.12 12.5 2.5 0.39 10.8 1.7 1.7 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-piccolo PF05715.8 KPI38228.1 - 0.17 11.9 0.6 0.27 11.2 0.4 1.3 1 0 0 1 1 1 0 Piccolo Zn-finger Lar_restr_allev PF14354.1 KPI38228.1 - 0.2 11.9 2.3 0.4 11.0 1.6 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar C1_4 PF07975.7 KPI38228.1 - 0.77 9.8 5.0 0.14 12.1 0.9 1.7 2 0 0 2 2 2 0 TFIIH C1-like domain IBR PF01485.16 KPI38228.1 - 1.2 9.0 4.6 0.71 9.7 1.5 1.8 1 1 1 2 2 2 0 IBR domain Fungal_trans_2 PF11951.3 KPI38229.1 - 5.4e-08 31.8 0.2 1.7e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI38229.1 - 1.6e-06 27.9 13.4 2.6e-06 27.2 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.15 KPI38230.1 - 2.5e-36 126.0 0.1 3.6e-36 125.4 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KPI38230.1 - 3.1e-19 70.0 0.5 1.8e-18 67.5 0.3 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KPI38230.1 - 9.2e-10 38.1 0.0 2.1e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KPI38230.1 - 6.7e-09 35.4 5.6 2.1e-07 30.5 0.6 2.7 1 1 0 2 2 2 2 Amidohydrolase family DHO_dh PF01180.16 KPI38230.1 - 0.096 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Hexokinase_2 PF03727.11 KPI38231.1 - 3.1e-76 255.7 0.0 5.3e-76 255.0 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KPI38231.1 - 3.8e-66 222.3 0.0 7.4e-66 221.3 0.0 1.5 1 0 0 1 1 1 1 Hexokinase Aldo_ket_red PF00248.16 KPI38231.1 - 4.2e-64 216.0 0.0 6.9e-64 215.3 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L32e PF01655.13 KPI38232.1 - 4.2e-48 161.9 0.9 5.6e-48 161.5 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 PseudoU_synth_2 PF00849.17 KPI38233.1 - 1.5e-24 86.7 0.0 6.1e-24 84.7 0.0 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 KPI38233.1 - 4.2e-05 22.8 0.1 8.1e-05 21.9 0.1 1.5 1 0 0 1 1 1 1 S4 domain Auto_anti-p27 PF06677.7 KPI38233.1 - 0.037 13.7 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) GFA PF04828.9 KPI38233.1 - 0.075 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme DNA_pol_delta_4 PF04081.8 KPI38234.1 - 3.9e-23 82.0 7.1 3.6e-22 78.9 4.9 2.0 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Cut8_N PF14482.1 KPI38234.1 - 0.62 10.1 9.8 0.18 11.8 4.0 2.2 2 1 0 2 2 2 0 Cut8 proteasome-binding domain AUX_IAA PF02309.11 KPI38234.1 - 2.8 7.6 8.5 3.9 7.1 5.9 1.2 1 0 0 1 1 1 0 AUX/IAA family CMV_1a PF12467.3 KPI38234.1 - 3.6 7.9 12.2 5.4 7.3 8.4 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family MFS_1 PF07690.11 KPI38235.1 - 1e-09 37.6 66.1 6.7e-09 34.9 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 KPI38236.1 - 5.8e-11 41.8 3.6 8.3e-08 31.8 0.1 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF3312 PF11768.3 KPI38236.1 - 0.0097 14.1 0.0 0.015 13.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 KPI38236.1 - 0.01 14.1 0.0 0.5 8.6 0.0 2.4 1 1 0 2 2 2 0 Cytochrome D1 heme domain DUF4613 PF15390.1 KPI38236.1 - 0.011 13.9 0.0 0.16 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) MRG PF05712.8 KPI38236.1 - 0.017 14.0 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 MRG DUF867 PF05908.6 KPI38236.1 - 0.091 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF867) SAP PF02037.22 KPI38237.1 - 0.087 12.3 0.2 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 SAP domain p450 PF00067.17 KPI38238.1 - 2e-71 240.9 0.0 2.3e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cyclase PF04199.8 KPI38239.1 - 1.5e-12 47.5 0.0 2.3e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase DHC_N1 PF08385.7 KPI38240.1 - 3.6e-163 544.0 0.2 3.6e-163 544.0 0.1 5.5 5 1 1 6 6 6 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KPI38240.1 - 2.4e-127 424.8 9.5 2.4e-127 424.8 6.6 4.4 7 0 0 7 7 7 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 KPI38240.1 - 7.2e-102 341.6 0.0 1.6e-101 340.5 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 KPI38240.1 - 8.1e-64 215.3 0.0 2.1e-63 213.9 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KPI38240.1 - 1.8e-40 138.6 0.4 2.8e-39 134.7 0.0 2.8 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KPI38240.1 - 7.8e-40 136.1 1.1 2.6e-39 134.4 0.0 2.5 3 0 0 3 3 3 1 ATP-binding dynein motor region D5 MT PF12777.2 KPI38240.1 - 1.8e-39 135.5 9.2 1.8e-39 135.5 6.4 2.3 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KPI38240.1 - 5.7e-30 103.8 1.3 7.3e-10 38.7 0.0 6.9 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KPI38240.1 - 1.1e-18 67.2 0.0 2.8e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA PF00004.24 KPI38240.1 - 4.7e-14 52.7 0.0 0.00079 19.6 0.0 5.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KPI38240.1 - 8.8e-13 48.5 0.2 0.036 14.2 0.1 6.2 5 1 0 5 5 4 3 AAA domain AAA_17 PF13207.1 KPI38240.1 - 8.3e-11 42.7 0.0 0.015 16.0 0.0 5.6 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 KPI38240.1 - 3e-10 40.1 0.0 0.26 11.1 0.0 5.4 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.1 KPI38240.1 - 1.5e-09 38.2 0.0 0.017 15.4 0.0 4.9 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 KPI38240.1 - 2.9e-06 27.4 15.4 0.13 12.1 0.1 8.6 8 1 1 9 9 8 2 AAA ATPase domain T2SE PF00437.15 KPI38240.1 - 3.6e-06 26.0 0.0 0.14 11.0 0.0 3.6 4 0 0 4 4 4 2 Type II/IV secretion system protein ABC_tran PF00005.22 KPI38240.1 - 7.9e-06 26.2 0.2 1.6 8.9 0.0 5.6 4 0 0 4 4 4 1 ABC transporter Mg_chelatase PF01078.16 KPI38240.1 - 5e-05 22.5 0.5 0.54 9.3 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KPI38240.1 - 6.4e-05 22.6 0.1 1 9.1 0.0 4.4 4 0 0 4 4 4 1 Part of AAA domain AAA_29 PF13555.1 KPI38240.1 - 0.00038 19.9 0.0 0.71 9.4 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain PduV-EutP PF10662.4 KPI38240.1 - 0.00093 18.6 0.3 3.2 7.2 0.1 3.8 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 KPI38240.1 - 0.0011 18.0 2.2 2.4 7.2 0.0 4.3 5 0 0 5 5 3 2 Zeta toxin AAA_25 PF13481.1 KPI38240.1 - 0.0013 18.1 0.1 0.62 9.4 0.0 3.7 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 KPI38240.1 - 0.0048 16.6 0.2 9 5.9 0.1 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KPI38240.1 - 0.011 14.8 0.0 12 5.0 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function, DUF258 Pol_alpha_B_N PF08418.5 KPI38241.1 - 6.2e-53 179.9 0.0 1.6e-52 178.5 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 KPI38241.1 - 4.9e-30 104.3 0.0 8.1e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CRAL_TRIO PF00650.15 KPI38242.1 - 3.5e-36 124.0 0.0 4.9e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KPI38242.1 - 1.6e-10 40.9 0.1 4.1e-10 39.6 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DnaJ PF00226.26 KPI38243.1 - 1.3e-13 50.4 0.3 2.4e-13 49.5 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain SNARE PF05739.14 KPI38244.1 - 1.3e-13 50.4 3.0 1.4e-13 50.3 1.3 1.7 2 0 0 2 2 2 1 SNARE domain KfrA_N PF11740.3 KPI38244.1 - 0.011 16.1 0.1 0.042 14.2 0.1 1.9 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Fusion_gly PF00523.13 KPI38244.1 - 0.12 10.4 0.1 1.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Fusion glycoprotein F0 CS PF04969.11 KPI38245.1 - 2.4e-08 34.3 0.0 3.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 CS domain Xol-1_GHMP-like PF09109.5 KPI38245.1 - 0.0061 16.6 1.1 0.01 15.9 0.5 1.5 2 0 0 2 2 2 1 Switch protein XOL-1, GHMP-like Rep_1 PF01446.12 KPI38245.1 - 0.012 14.9 0.0 0.012 14.9 0.0 1.5 2 0 0 2 2 2 0 Replication protein Nop14 PF04147.7 KPI38245.1 - 3.2 5.5 8.5 3.7 5.3 5.9 1.1 1 0 0 1 1 1 0 Nop14-like family UPRTase PF14681.1 KPI38246.1 - 2.3e-71 239.2 0.0 2.6e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KPI38246.1 - 3.7e-09 36.3 0.0 5.8e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.12 KPI38246.1 - 0.00069 18.7 0.3 0.073 12.1 0.1 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase/TENI P5CR_dimer PF14748.1 KPI38246.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation DEAD PF00270.24 KPI38248.1 - 5.9e-45 152.7 0.0 1e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KPI38248.1 - 2.7e-26 90.8 0.1 5.2e-26 89.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KPI38248.1 - 1.7e-20 72.6 0.0 4.3e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI38248.1 - 0.00071 19.4 0.6 0.0025 17.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KPI38248.1 - 0.023 14.6 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain Ferric_reduct PF01794.14 KPI38249.1 - 1.6e-18 67.0 18.4 1.6e-18 67.0 12.7 3.0 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KPI38249.1 - 4e-06 26.6 0.1 4.5e-05 23.2 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KPI38249.1 - 0.00023 21.1 2.2 0.16 11.8 0.1 2.6 1 1 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KPI38249.1 - 0.09 13.3 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain MLANA PF14991.1 KPI38249.1 - 1.9 8.5 5.8 0.28 11.2 1.2 1.7 2 0 0 2 2 2 0 Protein melan-A FLILHELTA PF10306.4 KPI38249.1 - 2.3 8.3 5.7 0.91 9.6 0.7 2.3 2 0 0 2 2 2 0 Hypothetical protein FLILHELTA His_Phos_2 PF00328.17 KPI38250.1 - 4.7e-13 49.1 0.0 4.4e-12 45.9 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Mid2 PF04478.7 KPI38250.1 - 0.095 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor ALO PF04030.9 KPI38251.1 - 2.8e-86 289.3 0.2 3.7e-86 288.9 0.1 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KPI38251.1 - 2.6e-17 62.5 0.1 1.3e-14 53.8 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain Ribosomal_S19 PF00203.16 KPI38252.1 - 3.4e-19 68.2 0.1 4.1e-19 67.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Tannase PF07519.6 KPI38253.1 - 4.3e-100 335.6 1.5 4.5e-99 332.3 1.0 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KPI38253.1 - 1.1e-05 25.4 4.2 2.1e-05 24.5 1.0 2.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI38253.1 - 6.4e-05 22.7 1.7 0.0037 17.0 1.2 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KPI38253.1 - 0.00017 21.1 0.5 0.00028 20.4 0.3 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KPI38253.1 - 0.0045 16.2 0.1 0.21 10.7 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KPI38253.1 - 0.019 14.5 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PHP PF02811.14 KPI38254.1 - 0.00047 19.9 0.0 0.00089 19.0 0.0 1.4 1 0 0 1 1 1 1 PHP domain PHP_C PF13263.1 KPI38254.1 - 0.0017 17.7 0.0 0.0034 16.8 0.0 1.5 1 0 0 1 1 1 1 PHP-associated MFS_1 PF07690.11 KPI38256.1 - 2.7e-12 46.0 28.7 2.7e-12 46.0 19.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KPI38256.1 - 1.4e-09 37.6 7.9 1.4e-09 37.6 5.5 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 KPI38256.1 - 0.062 11.8 18.4 0.065 11.8 1.0 2.3 2 0 0 2 2 2 0 Sugar (and other) transporter MFS_1 PF07690.11 KPI38257.1 - 3.4e-22 78.6 16.1 3.4e-22 78.6 11.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 KPI38257.1 - 0.00045 19.5 2.8 0.00045 19.5 2.0 2.3 2 1 0 2 2 2 1 Nodulin-like Fungal_trans_2 PF11951.3 KPI38258.1 - 9.3e-29 100.1 2.0 1.1e-28 99.9 1.4 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 KPI38259.1 - 6.6e-07 29.3 0.1 1.2e-06 28.5 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KPI38259.1 - 5e-05 23.3 0.0 7.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KPI38259.1 - 0.0001 22.1 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.14 KPI38259.1 - 0.02 14.0 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KPI38259.1 - 0.022 13.6 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain TctC PF03401.9 KPI38259.1 - 0.023 13.6 0.1 0.059 12.2 0.0 1.6 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter family receptor Shikimate_DH PF01488.15 KPI38259.1 - 0.089 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KPI38259.1 - 0.092 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KPI38259.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NIR_SIR PF01077.17 KPI38260.1 - 1.3e-49 167.5 0.0 1.8e-42 144.3 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KPI38260.1 - 2.9e-27 94.0 0.0 2e-12 46.5 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 KPI38260.1 - 3.1e-27 95.3 0.0 6.2e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 KPI38260.1 - 1.9e-06 27.5 0.1 4.8e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg COesterase PF00135.23 KPI38261.1 - 1e-85 288.5 0.6 1.4e-85 288.0 0.4 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI38261.1 - 8.2e-06 25.5 1.0 0.00013 21.6 0.1 3.1 3 1 0 3 3 3 1 alpha/beta hydrolase fold RNase_PH PF01138.16 KPI38262.1 - 2.1e-25 89.5 0.0 3.8e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Parecho_VpG PF06344.6 KPI38263.1 - 0.32 10.9 2.0 1.1 9.2 1.4 1.9 1 0 0 1 1 1 0 Parechovirus Genome-linked protein MFS_1 PF07690.11 KPI38264.1 - 2.3e-11 43.0 18.5 2.3e-11 43.0 12.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Oxidored_FMN PF00724.15 KPI38265.1 - 7.5e-74 248.7 0.0 1e-73 248.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Rep_fac-A_3 PF08661.6 KPI38267.1 - 3.8e-18 65.3 0.0 4.7e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 Mito_carr PF00153.22 KPI38268.1 - 8.9e-57 188.8 3.3 3.7e-20 71.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Kinetochor_Ybp2 PF08568.5 KPI38269.1 - 3e-70 237.2 0.0 4.5e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin TauD PF02668.11 KPI38271.1 - 1.4e-45 155.9 0.6 1.8e-45 155.6 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cu-oxidase_2 PF07731.9 KPI38272.1 - 7.6e-41 138.8 4.9 9.2e-36 122.3 2.5 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KPI38272.1 - 3.2e-21 75.2 9.3 9.1e-20 70.5 0.2 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 KPI38272.1 - 8.6e-15 54.9 0.2 1.3e-11 44.7 0.0 3.4 3 0 0 3 3 3 1 Multicopper oxidase RNA_pol_Rpc4 PF05132.9 KPI38273.1 - 1.6e-20 73.4 1.1 1.6e-20 73.4 0.7 4.2 3 1 0 3 3 3 1 RNA polymerase III RPC4 F-box-like PF12937.2 KPI38274.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 F-box-like MIF4G PF02854.14 KPI38275.1 - 4.6e-50 169.9 0.1 6.6e-50 169.4 0.1 1.2 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KPI38275.1 - 2.8e-19 68.7 1.6 9.9e-19 67.0 1.1 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Borrelia_P83 PF05262.6 KPI38275.1 - 0.0011 17.2 26.8 0.0011 17.2 18.6 1.5 2 0 0 2 2 2 1 Borrelia P83/100 protein EzrA PF06160.7 KPI38276.1 - 0.018 13.2 4.6 0.022 12.9 3.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.5 KPI38276.1 - 0.046 13.8 3.8 0.073 13.1 2.6 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Birna_RdRp PF04197.7 KPI38276.1 - 0.063 11.3 0.7 0.072 11.1 0.5 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) DUF1732 PF08340.6 KPI38276.1 - 0.064 13.0 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) Cluap1 PF10234.4 KPI38276.1 - 0.064 12.4 4.4 0.16 11.1 1.3 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 ApoB100_C PF12491.3 KPI38276.1 - 0.14 11.7 2.2 0.32 10.6 0.0 2.2 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal IncA PF04156.9 KPI38276.1 - 0.74 9.3 3.4 1.1 8.7 2.4 1.3 1 0 0 1 1 1 0 IncA protein CN_hydrolase PF00795.17 KPI38277.1 - 2.2e-16 59.7 0.0 3.1e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.11 KPI38279.1 - 1.6e-38 132.3 19.8 2.3e-38 131.7 13.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF308 PF03729.8 KPI38279.1 - 3.6 7.6 14.7 2.8 7.9 0.1 3.4 4 0 0 4 4 4 0 Short repeat of unknown function (DUF308) HSBP1 PF06825.7 KPI38280.1 - 5.9e-12 44.9 1.1 7.9e-12 44.5 0.8 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF4319 PF14203.1 KPI38280.1 - 0.0099 15.4 0.3 0.015 14.8 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4319) DUF935 PF06074.7 KPI38280.1 - 0.015 14.0 1.1 0.018 13.7 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) SPX PF03105.14 KPI38280.1 - 0.051 13.3 0.1 0.056 13.2 0.1 1.0 1 0 0 1 1 1 0 SPX domain DUF4266 PF14086.1 KPI38280.1 - 0.45 11.0 0.1 0.45 11.0 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4266) FlxA PF14282.1 KPI38281.1 - 0.021 14.7 0.3 0.03 14.2 0.2 1.2 1 0 0 1 1 1 0 FlxA-like protein Prefoldin_2 PF01920.15 KPI38281.1 - 0.045 13.5 0.1 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Prefoldin subunit HAD_2 PF13419.1 KPI38282.1 - 3.9e-25 89.0 0.0 4.8e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Amidase PF01425.16 KPI38283.1 - 3.1e-84 283.3 0.0 5.6e-84 282.5 0.0 1.4 1 1 0 1 1 1 1 Amidase ORC6 PF05460.8 KPI38286.1 - 2.6e-34 118.8 1.1 7.1e-26 91.1 3.9 2.2 1 1 1 2 2 2 2 Origin recognition complex subunit 6 (ORC6) HTH_AsnC-type PF13404.1 KPI38287.1 - 0.019 14.4 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 KPI38287.1 - 0.14 11.5 0.0 4.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Clp1 PF06807.9 KPI38288.1 - 7e-17 61.8 0.0 1.4e-15 57.6 0.0 2.3 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KPI38288.1 - 5e-08 32.7 0.0 8.9e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KPI38288.1 - 0.00025 20.7 0.5 0.00055 19.6 0.4 1.5 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 KPI38288.1 - 0.00031 21.0 0.0 0.00064 20.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 KPI38288.1 - 0.00065 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KPI38288.1 - 0.0017 19.1 0.1 0.0031 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KPI38288.1 - 0.0025 17.9 0.1 0.0044 17.2 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KPI38288.1 - 0.0031 17.0 0.1 0.0085 15.5 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain PduV-EutP PF10662.4 KPI38288.1 - 0.0041 16.6 0.0 0.0072 15.8 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KPI38288.1 - 0.005 16.4 0.1 0.0089 15.5 0.1 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 KPI38288.1 - 0.0077 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 KPI38288.1 - 0.013 15.5 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KPI38288.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus SRP54 PF00448.17 KPI38288.1 - 0.028 13.8 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 KPI38288.1 - 0.037 14.1 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KPI38288.1 - 0.039 13.5 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KPI38288.1 - 0.043 13.7 0.0 0.089 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KPI38288.1 - 0.055 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KPI38288.1 - 0.058 12.5 0.0 0.28 10.3 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 KPI38288.1 - 0.079 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 KPI38288.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 KPI38288.1 - 0.095 11.8 0.1 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 KPI38288.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 KPI38288.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KPI38288.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF221 PF02714.10 KPI38289.1 - 1.8e-64 217.6 10.5 1.8e-64 217.6 7.3 1.6 1 1 1 2 2 2 1 Domain of unknown function DUF221 DUF3779 PF12621.3 KPI38289.1 - 3.9e-31 106.7 0.2 5.7e-31 106.2 0.1 1.2 1 0 0 1 1 1 1 Phosphate metabolism protein Amidohydro_2 PF04909.9 KPI38292.1 - 1.5e-05 24.7 0.0 2.3e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase UxaC PF02614.9 KPI38292.1 - 0.22 10.0 0.7 0.38 9.3 0.5 1.3 1 0 0 1 1 1 0 Glucuronate isomerase p450 PF00067.17 KPI38293.1 - 1e-45 156.1 0.0 1.3e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Spc97_Spc98 PF04130.8 KPI38294.1 - 1.9e-60 204.7 0.0 2.6e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Rhomboid PF01694.17 KPI38295.1 - 4.9e-36 123.9 12.8 4.9e-36 123.9 8.9 2.1 2 0 0 2 2 2 1 Rhomboid family DUF4231 PF14015.1 KPI38295.1 - 0.055 13.4 1.6 3.5 7.6 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Nrf1_DNA-bind PF10491.4 KPI38295.1 - 0.82 8.7 2.8 0.61 9.1 0.1 2.0 2 0 0 2 2 2 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 GATA PF00320.22 KPI38296.1 - 3.6e-05 23.0 7.4 0.0013 18.0 0.1 2.6 2 0 0 2 2 2 2 GATA zinc finger DUF2421 PF10334.4 KPI38296.1 - 0.13 11.8 0.1 0.62 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2421) AflR PF08493.5 KPI38297.1 - 0.07 12.1 3.1 0.11 11.5 2.1 1.4 1 0 0 1 1 1 0 Aflatoxin regulatory protein zf-CCCH PF00642.19 KPI38298.1 - 1e-05 25.0 2.6 1e-05 25.0 1.8 2.5 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pex2_Pex12 PF04757.9 KPI38299.1 - 1.7e-52 178.1 8.2 2.1e-52 177.8 5.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 KPI38299.1 - 0.0018 18.0 0.3 0.0031 17.2 0.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KPI38299.1 - 0.0055 16.6 0.2 0.0095 15.9 0.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) NIF PF03031.13 KPI38300.1 - 1.8e-38 131.6 0.1 2.9e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KPI38300.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Aa_trans PF01490.13 KPI38301.1 - 7.4e-22 77.3 30.9 9.2e-22 77.0 21.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MARVEL PF01284.18 KPI38302.1 - 0.00023 20.9 7.9 0.00046 20.0 5.5 1.4 1 1 1 2 2 2 2 Membrane-associating domain DUF4293 PF14126.1 KPI38302.1 - 0.11 12.3 1.1 0.19 11.6 0.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) TRF PF08558.5 KPI38303.1 - 0.003 16.9 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) adh_short PF00106.20 KPI38304.1 - 2.5e-10 40.5 0.0 4.7e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI38304.1 - 1.7e-08 34.5 0.0 3.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI38304.1 - 4.9e-06 26.3 0.0 1.7e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 KR domain Saccharop_dh PF03435.13 KPI38304.1 - 5e-05 22.4 0.0 8.4e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase GMC_oxred_N PF00732.14 KPI38305.1 - 5.6e-58 196.4 0.0 7e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI38305.1 - 9.4e-21 74.6 0.1 1.6e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KPI38305.1 - 0.0018 17.2 0.6 0.0069 15.3 0.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI38305.1 - 0.0077 16.2 0.3 0.033 14.2 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KPI38305.1 - 0.025 14.9 0.3 9.5 6.7 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI38305.1 - 0.027 13.4 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein UPF0075 PF03702.9 KPI38305.1 - 0.053 12.4 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) Trp_halogenase PF04820.9 KPI38305.1 - 0.057 12.0 0.0 0.094 11.3 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Aminotran_3 PF00202.16 KPI38307.1 - 4.1e-53 180.4 0.0 5.7e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III RSN1_TM PF13967.1 KPI38308.1 - 7.3e-44 149.0 2.2 1.3e-43 148.2 1.5 1.4 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KPI38308.1 - 1e-20 74.0 0.2 1.8e-20 73.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF2418 PF10332.4 KPI38308.1 - 0.05 13.9 0.8 0.2 11.9 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2418) GP41 PF00517.12 KPI38309.1 - 0.054 13.0 0.5 0.088 12.3 0.1 1.5 2 0 0 2 2 2 0 Retroviral envelope protein NfeD PF01957.13 KPI38309.1 - 0.49 10.5 6.9 1.6 8.8 0.1 2.4 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding DUF4389 PF14333.1 KPI38309.1 - 4.4 7.0 5.4 3.1 7.5 2.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) ADP_ribosyl_GH PF03747.9 KPI38310.1 - 4.8e-30 105.3 0.1 5.6e-30 105.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Kinesin PF00225.18 KPI38311.1 - 2.8e-95 318.8 0.2 5e-95 318.0 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF87 PF01935.12 KPI38311.1 - 0.32 10.7 6.7 0.61 9.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 HET PF06985.6 KPI38312.1 - 0.00084 19.5 0.0 0.0024 18.0 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aa_trans PF01490.13 KPI38313.1 - 1.6e-23 82.8 25.7 2.1e-23 82.5 17.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2975 PF11188.3 KPI38313.1 - 0.012 15.2 1.5 0.012 15.2 1.1 3.1 2 2 2 4 4 4 0 Protein of unknown function (DUF2975) MFS_1 PF07690.11 KPI38314.1 - 0.028 13.1 0.2 0.036 12.7 0.1 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily ADH_N PF08240.7 KPI38315.1 - 3.8e-27 94.1 3.7 6.7e-27 93.4 2.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI38315.1 - 7.5e-16 57.8 0.0 5.2e-15 55.1 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KPI38315.1 - 0.0047 16.1 0.0 0.0077 15.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KPI38315.1 - 0.013 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 KPI38315.1 - 0.036 13.7 0.3 0.11 12.1 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KPI38315.1 - 0.049 13.1 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 KPI38315.1 - 0.096 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 KPI38315.1 - 0.11 12.0 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pyr_redox PF00070.22 KPI38315.1 - 0.16 12.3 1.0 1.4 9.3 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KPI38315.1 - 0.24 11.2 2.6 0.34 10.7 1.1 1.8 2 0 0 2 2 2 0 ThiF family adh_short PF00106.20 KPI38317.1 - 1.7e-21 76.8 0.0 2.2e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI38317.1 - 1.8e-09 37.7 0.0 2.8e-09 37.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI38317.1 - 4.5e-07 29.7 0.0 1e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KPI38317.1 - 1.5e-06 28.3 0.0 2.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 KPI38317.1 - 8.9e-05 22.2 0.2 0.00024 20.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 KPI38317.1 - 0.0093 14.9 0.3 0.015 14.3 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KPI38317.1 - 0.033 13.0 0.1 0.077 11.8 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.1 KPI38317.1 - 0.039 14.2 0.2 0.11 12.7 0.1 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding LSM PF01423.17 KPI38318.1 - 6.1e-19 67.3 0.5 8.2e-19 66.9 0.3 1.1 1 0 0 1 1 1 1 LSM domain 4F5 PF04419.9 KPI38319.1 - 3.1e-10 40.5 7.5 3.1e-10 40.5 5.2 2.1 2 0 0 2 2 2 2 4F5 protein family DEAD PF00270.24 KPI38320.1 - 9.6e-47 158.6 0.1 9.1e-46 155.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI38320.1 - 7.6e-24 83.3 0.0 2.8e-23 81.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 KPI38320.1 - 1.3e-22 79.3 3.2 3.6e-22 77.9 2.2 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Toprim_2 PF13155.1 KPI38320.1 - 0.04 14.2 0.1 0.27 11.5 0.0 2.6 2 1 0 2 2 2 0 Toprim-like Glyco_hydro_72 PF03198.9 KPI38321.1 - 2e-99 332.5 0.0 2.4e-99 332.2 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Podoplanin PF05808.6 KPI38321.1 - 0.00015 21.3 0.8 0.00027 20.5 0.6 1.4 1 0 0 1 1 1 1 Podoplanin Cellulase PF00150.13 KPI38321.1 - 0.00068 18.9 0.1 0.0077 15.4 0.1 2.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1191 PF06697.7 KPI38321.1 - 0.056 12.2 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Snf7 PF03357.16 KPI38322.1 - 1.7e-15 56.8 14.2 2.7e-15 56.1 9.9 1.2 1 0 0 1 1 1 1 Snf7 DUF29 PF01724.11 KPI38322.1 - 0.32 10.8 8.6 0.078 12.8 3.0 2.1 2 1 0 3 3 3 0 Domain of unknown function DUF29 Fungal_trans PF04082.13 KPI38323.1 - 2.6e-59 200.2 0.0 4.3e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KPI38323.1 - 0.00013 22.1 13.8 0.0018 18.4 2.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KPI38323.1 - 0.00022 21.3 9.7 0.0017 18.5 1.7 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KPI38323.1 - 0.0034 17.6 2.4 0.0034 17.6 1.7 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger Hist_deacetyl PF00850.14 KPI38324.1 - 1.5e-77 260.9 0.0 2.9e-77 260.0 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain PIP49_C PF12260.3 KPI38324.1 - 0.022 14.1 1.0 0.099 12.0 0.1 2.3 3 0 0 3 3 3 0 Protein-kinase domain of FAM69 dCMP_cyt_deam_1 PF00383.17 KPI38325.1 - 1.3e-13 50.4 0.0 2.6e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 KPI38325.1 - 0.00038 20.1 0.0 0.00044 19.9 0.0 1.3 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Ring_hydroxyl_A PF00848.14 KPI38326.1 - 4.2e-35 121.3 3.5 6.3e-34 117.4 2.4 2.1 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 KPI38326.1 - 6.7e-15 54.4 0.0 1.3e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain SAP PF02037.22 KPI38327.1 - 0.00015 21.1 0.0 0.00035 19.9 0.0 1.7 1 0 0 1 1 1 1 SAP domain F-box-like_2 PF13013.1 KPI38327.1 - 0.024 14.3 0.7 0.19 11.4 0.1 2.5 2 1 0 2 2 2 0 F-box-like domain LETM1 PF07766.8 KPI38327.1 - 0.069 12.1 0.1 0.14 11.2 0.1 1.4 1 0 0 1 1 1 0 LETM1-like protein JAB PF01398.16 KPI38328.1 - 8.3e-35 118.9 0.0 1.5e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KPI38328.1 - 1.7e-23 82.8 0.2 3.4e-23 81.8 0.2 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KPI38328.1 - 4e-09 36.0 0.0 6.5e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4460 PF14687.1 KPI38328.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) Abhydrolase_1 PF00561.15 KPI38329.1 - 1.2e-17 64.2 0.0 2.8e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 KPI38329.1 - 2e-12 46.8 0.1 6e-12 45.3 0.1 1.9 1 1 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 KPI38329.1 - 1.1e-09 38.5 0.0 2.3e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family 2-Hacid_dh_C PF02826.14 KPI38330.1 - 3.1e-41 140.4 0.0 4.1e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KPI38330.1 - 4.5e-17 61.7 0.0 5.4e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KPI38330.1 - 6.9e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AMP-binding PF00501.23 KPI38331.1 - 8.8e-49 165.9 3.3 8.5e-21 73.8 0.0 3.1 2 1 1 3 3 3 3 AMP-binding enzyme AMP-binding_C PF13193.1 KPI38331.1 - 0.016 16.1 0.0 0.032 15.1 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain BTB PF00651.26 KPI38332.1 - 3.3e-10 39.9 0.6 5.9e-10 39.1 0.1 1.6 2 0 0 2 2 2 1 BTB/POZ domain Lbh PF15317.1 KPI38332.1 - 0.028 14.6 0.1 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 Cardiac transcription factor regulator, Developmental protein ERM PF00769.14 KPI38332.1 - 0.079 12.4 2.9 0.13 11.8 2.0 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family VSP PF03302.8 KPI38333.1 - 0.019 13.6 10.2 0.041 12.5 7.1 1.6 1 1 0 1 1 1 0 Giardia variant-specific surface protein P12 PF12669.2 KPI38333.1 - 0.16 12.2 0.2 0.36 11.0 0.1 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family SKG6 PF08693.5 KPI38333.1 - 0.17 11.1 2.0 0.45 9.8 1.4 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glyco_hydro_2_C PF02836.12 KPI38334.1 - 1.5e-73 247.2 0.0 2.2e-73 246.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 KPI38334.1 - 3.3e-56 190.3 0.1 5.4e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_42 PF02449.10 KPI38334.1 - 0.0067 15.5 0.2 0.025 13.6 0.2 1.8 2 0 0 2 2 2 1 Beta-galactosidase Apc5 PF12862.2 KPI38334.1 - 0.03 14.1 0.1 0.088 12.6 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 Tox-HNH-EHHH PF15657.1 KPI38334.1 - 1.1 9.4 4.6 0.42 10.8 0.3 2.5 3 0 0 3 3 3 0 HNH/Endo VII superfamily nuclease toxins Ras PF00071.17 KPI38335.1 - 1.5e-55 186.9 0.2 2.1e-55 186.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KPI38335.1 - 3.6e-21 75.8 0.1 5.6e-21 75.2 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KPI38335.1 - 2.1e-17 62.9 0.1 2.4e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KPI38335.1 - 5.6e-08 32.4 0.0 2.7e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KPI38335.1 - 1.8e-06 27.2 0.1 2.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KPI38335.1 - 2.6e-06 26.8 0.0 3.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KPI38335.1 - 1.3e-05 25.1 0.0 2.1e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KPI38335.1 - 0.033 14.3 0.0 2 8.5 0.0 2.5 1 1 1 2 2 2 0 AAA domain Dynamin_N PF00350.18 KPI38335.1 - 0.035 13.9 0.0 2.8 7.7 0.0 2.6 2 1 1 3 3 3 0 Dynamin family PduV-EutP PF10662.4 KPI38335.1 - 0.12 11.8 0.3 0.39 10.2 0.2 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Fungal_trans PF04082.13 KPI38336.1 - 6.7e-20 71.0 0.0 2.1e-19 69.4 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain B-block_TFIIIC PF04182.7 KPI38337.1 - 2.3e-13 49.8 0.0 4.7e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 KPI38337.1 - 0.00057 19.4 1.5 0.0088 15.6 0.0 3.3 3 0 0 3 3 3 1 MarR family HTH_27 PF13463.1 KPI38337.1 - 0.0057 16.9 0.7 0.039 14.2 0.0 2.8 3 0 0 3 3 3 1 Winged helix DNA-binding domain OmdA PF13376.1 KPI38337.1 - 0.037 13.6 1.6 2.4 7.8 0.0 3.6 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated Fmp27 PF10344.4 KPI38338.1 - 1.7e-186 621.6 0.2 9.3e-186 619.2 0.1 2.0 1 1 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 KPI38338.1 - 2.7e-160 534.1 0.5 2.7e-160 534.1 0.3 2.1 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 KPI38338.1 - 4.1e-137 457.4 7.8 4.1e-137 457.4 5.4 3.5 3 1 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KPI38338.1 - 4.7e-54 182.3 0.4 1.2e-53 181.0 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.4 KPI38338.1 - 8.9e-50 168.6 0.0 2e-49 167.4 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.4 KPI38338.1 - 1.3e-29 102.6 0.0 4.1e-29 101.0 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain AMP-binding PF00501.23 KPI38339.1 - 7.1e-84 281.6 0.0 9.2e-84 281.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI38339.1 - 2.3e-14 54.0 0.1 6.9e-14 52.5 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF812 PF05667.6 KPI38340.1 - 0.0039 15.7 31.0 0.005 15.4 9.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF812) bZIP_1 PF00170.16 KPI38340.1 - 0.0067 16.3 2.1 0.0067 16.3 1.4 5.5 6 2 1 7 7 6 1 bZIP transcription factor Macoilin PF09726.4 KPI38340.1 - 0.014 13.6 30.0 0.027 12.8 9.8 2.1 1 1 1 2 2 2 0 Transmembrane protein Reo_sigmaC PF04582.7 KPI38340.1 - 0.042 13.0 11.4 0.21 10.7 1.2 3.0 2 1 1 3 3 3 0 Reovirus sigma C capsid protein IncA PF04156.9 KPI38340.1 - 0.36 10.3 44.0 0.7 9.4 7.8 3.5 2 1 0 2 2 2 0 IncA protein KH_5 PF13184.1 KPI38340.1 - 0.42 10.4 3.1 3.2 7.6 0.1 3.0 3 0 0 3 3 3 0 NusA-like KH domain Osmo_CC PF08946.5 KPI38340.1 - 0.71 9.9 14.4 0.2 11.7 0.2 4.0 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Baculo_PEP_C PF04513.7 KPI38340.1 - 0.74 9.6 18.8 0.044 13.6 2.3 3.5 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.4 KPI38340.1 - 0.91 9.3 47.8 0.017 15.0 12.3 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 KPI38340.1 - 1.3 7.6 37.6 0.079 11.6 11.2 2.9 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.7 KPI38340.1 - 1.5 8.6 14.8 4.5 7.0 4.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 KPI38340.1 - 1.8 8.5 15.7 2.9 7.8 2.4 4.7 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Atg14 PF10186.4 KPI38340.1 - 2.7 6.8 34.9 1.7 7.5 11.9 2.4 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 KPI38340.1 - 5.7 5.2 34.9 0.34 9.3 11.7 2.6 2 1 0 2 2 2 0 AAA domain Seryl_tRNA_N PF02403.17 KPI38340.1 - 7.6 6.6 37.1 0.027 14.4 8.1 3.6 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF99 PF01949.11 KPI38340.1 - 7.8 5.5 6.6 3.8 6.5 0.0 2.7 3 1 1 4 4 4 0 Protein of unknown function DUF99 Cullin PF00888.17 KPI38341.1 - 7.5e-126 421.0 5.8 9.5e-126 420.6 4.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KPI38341.1 - 9.2e-24 83.0 1.0 3.4e-23 81.2 0.7 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Antimicrobial_4 PF08024.6 KPI38341.1 - 0.012 15.3 1.1 0.03 14.1 0.8 1.6 1 0 0 1 1 1 0 Ant antimicrobial peptide HTH_34 PF13601.1 KPI38341.1 - 0.016 15.2 0.0 0.62 10.1 0.0 2.7 2 0 0 2 2 2 0 Winged helix DNA-binding domain TrmB PF01978.14 KPI38341.1 - 0.053 13.2 0.2 6.3 6.5 0.1 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Sugar_tr PF00083.19 KPI38342.1 - 9.7e-75 251.8 23.3 2.3e-49 168.1 2.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI38342.1 - 5.2e-22 78.0 34.7 1.9e-19 69.6 9.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MaoC_dehydratas PF01575.14 KPI38343.1 - 0.00012 21.4 0.1 0.00023 20.5 0.1 1.4 1 0 0 1 1 1 1 MaoC like domain MR_MLE_C PF13378.1 KPI38344.1 - 2.3e-21 75.8 0.0 3.5e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KPI38344.1 - 3.6e-09 37.0 0.0 8.8e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KPI38344.1 - 2.6e-08 33.8 0.0 4.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Xpo1 PF08389.7 KPI38347.1 - 3.1e-26 92.0 0.2 1.9e-24 86.2 0.0 3.5 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 KPI38347.1 - 1.4e-11 44.0 1.5 5.9e-11 42.1 0.4 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 KPI38347.1 - 0.0016 18.6 1.5 0.13 12.5 0.0 4.0 4 1 1 5 5 5 2 HEAT repeats Sec8_exocyst PF04048.9 KPI38347.1 - 0.041 13.5 0.4 0.15 11.6 0.3 2.0 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain HEAT PF02985.17 KPI38347.1 - 0.078 13.0 0.0 4.9 7.5 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat DUF1043 PF06295.7 KPI38347.1 - 0.085 12.5 0.0 0.97 9.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Cupin_1 PF00190.17 KPI38349.1 - 6.8e-15 54.7 0.1 9.3e-15 54.3 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 KPI38349.1 - 0.00045 19.6 0.0 0.00077 18.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Zn_clus PF00172.13 KPI38350.1 - 8.2e-06 25.6 13.5 1.3e-05 24.9 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 KPI38353.1 - 0.18 11.1 23.0 0.33 10.2 15.9 1.5 1 0 0 1 1 1 0 Vta1 like Zn_clus PF00172.13 KPI38354.1 - 0.00035 20.4 12.1 0.00066 19.5 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 KPI38354.1 - 0.057 12.6 0.0 0.2 10.9 0.0 1.9 1 0 0 1 1 1 0 Histone chaperone domain CHZ DnaJ PF00226.26 KPI38355.1 - 1.5e-21 75.8 3.2 1.5e-21 75.8 2.2 2.3 2 0 0 2 2 2 1 DnaJ domain EntA_Immun PF08951.5 KPI38355.1 - 0.051 13.7 0.5 5.7 7.1 0.1 2.8 2 0 0 2 2 2 0 Enterocin A Immunity PFEMP PF03011.10 KPI38355.1 - 6.7 7.0 7.9 6.2 7.1 3.2 2.5 1 1 1 2 2 2 0 PFEMP DBL domain XAP5 PF04921.9 KPI38356.1 - 1.4e-70 237.6 1.5 2e-70 237.0 1.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator TFIID_30kDa PF03540.8 KPI38357.1 - 2.8e-21 75.0 0.6 7.6e-21 73.6 0.4 1.7 1 1 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 KPI38357.1 - 0.073 13.5 1.1 0.073 13.5 0.8 2.2 2 1 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Mre11_DNA_bind PF04152.9 KPI38358.1 - 2.3e-55 187.1 2.2 2.3e-55 187.1 1.5 1.9 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KPI38358.1 - 2.8e-28 98.6 3.3 4e-28 98.1 2.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KPI38358.1 - 0.00015 21.6 1.0 0.00043 20.1 0.7 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain alpha-hel2 PF14456.1 KPI38358.1 - 0.095 11.4 6.3 0.19 10.4 4.4 1.4 1 0 0 1 1 1 0 Alpha-helical domain 2 AMP-binding PF00501.23 KPI38359.1 - 1.6e-65 221.1 0.0 2.1e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI38359.1 - 2.6e-15 57.0 1.7 3.9e-15 56.5 0.4 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Amidase PF01425.16 KPI38360.1 - 9e-17 61.0 0.8 7.5e-15 54.7 0.2 2.5 2 1 0 2 2 2 1 Amidase DUF3904 PF13044.1 KPI38360.1 - 0.031 12.6 0.0 0.053 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3904) PEX11 PF05648.9 KPI38361.1 - 1.5e-05 24.4 1.7 6e-05 22.4 1.2 2.1 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) CENP-T PF15511.1 KPI38363.1 - 1.2e-34 120.2 34.2 1.9e-33 116.3 23.7 2.5 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 KPI38363.1 - 2.8e-05 24.2 0.0 6.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Kinetochore component CENP-S ORC6 PF05460.8 KPI38363.1 - 6.2 5.8 14.4 0.42 9.6 6.2 1.7 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) IPK PF03770.11 KPI38364.1 - 1.3e-55 188.0 0.0 1.7e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF1798 PF08807.5 KPI38364.1 - 0.1 12.3 0.1 0.64 9.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) Kinesin PF00225.18 KPI38365.1 - 2.1e-91 306.1 0.0 6.9e-91 304.4 0.0 1.9 1 0 0 1 1 1 1 Kinesin motor domain ERp29 PF07749.7 KPI38365.1 - 0.0029 18.2 0.9 0.0029 18.2 0.6 4.2 4 1 1 5 5 5 1 Endoplasmic reticulum protein ERp29, C-terminal domain ApoO PF09769.4 KPI38365.1 - 4.5 6.9 17.0 0.053 13.2 0.2 4.6 3 1 1 4 4 4 0 Apolipoprotein O Sulfatase PF00884.18 KPI38366.1 - 5.4e-24 84.9 0.0 7e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 KPI38366.1 - 0.00014 20.4 0.0 0.00016 20.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 KPI38366.1 - 0.0055 16.9 0.2 0.22 11.7 0.1 2.4 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase MMR_HSR1 PF01926.18 KPI38367.1 - 1.3e-08 34.7 0.0 3.4e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KPI38367.1 - 1e-05 24.7 0.5 4.2e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 KPI38367.1 - 1.6e-05 24.1 0.0 3.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KPI38367.1 - 0.0003 20.6 5.6 0.039 13.7 0.2 3.2 2 2 1 3 3 3 2 Dynamin family SRPRB PF09439.5 KPI38367.1 - 0.0041 16.3 0.2 0.11 11.6 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_17 PF13207.1 KPI38367.1 - 0.0051 17.6 0.3 0.029 15.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain IIGP PF05049.8 KPI38367.1 - 0.0088 14.8 0.0 0.021 13.6 0.0 1.5 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.1 KPI38367.1 - 0.015 15.4 2.7 0.34 11.0 0.0 2.9 2 2 1 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 KPI38367.1 - 0.021 14.2 0.1 0.06 12.8 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.7 KPI38367.1 - 0.039 13.0 0.2 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 KPI38367.1 - 0.068 12.5 0.5 1.7 7.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KPI38367.1 - 0.068 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KPI38367.1 - 0.075 13.3 0.3 0.6 10.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Septin PF00735.13 KPI38367.1 - 0.085 11.8 0.0 0.38 9.7 0.0 2.1 2 1 0 2 2 2 0 Septin FadA PF09403.5 KPI38367.1 - 0.093 12.7 0.2 0.093 12.7 0.2 2.2 2 1 0 2 2 2 0 Adhesion protein FadA AAA_16 PF13191.1 KPI38367.1 - 0.13 12.2 6.2 0.23 11.4 0.0 2.7 3 1 0 3 3 2 0 AAA ATPase domain FeoB_N PF02421.13 KPI38367.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B KAP_NTPase PF07693.9 KPI38367.1 - 0.24 10.3 2.0 0.9 8.4 0.8 2.2 1 1 0 1 1 1 0 KAP family P-loop domain ATP_bind_1 PF03029.12 KPI38367.1 - 0.26 10.7 2.0 0.41 10.1 0.1 2.3 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 KPI38367.1 - 0.3 11.4 2.2 3 8.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KPI38367.1 - 0.3 10.9 3.6 0.54 10.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KPI38367.1 - 4.4 7.5 0.0 4.4 7.5 0.0 2.9 2 1 0 2 2 1 0 AAA domain DUF87 PF01935.12 KPI38367.1 - 4.7 6.9 6.3 1 9.1 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF87 Fungal_trans PF04082.13 KPI38368.1 - 7e-20 70.9 0.1 1.1e-19 70.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain 5-FTHF_cyc-lig PF01812.15 KPI38369.1 - 7.7e-36 123.6 0.0 9.1e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Fungal_trans_2 PF11951.3 KPI38370.1 - 0.023 13.2 1.1 0.085 11.4 0.8 2.0 1 1 0 1 1 1 0 Fungal specific transcription factor domain adh_short PF00106.20 KPI38372.1 - 6.9e-26 91.1 1.1 3.5e-25 88.8 0.8 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI38372.1 - 6.8e-23 81.6 0.0 8.1e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI38372.1 - 3.8e-12 46.2 0.4 1.2e-11 44.6 0.3 1.7 1 1 0 1 1 1 1 KR domain UreD PF01774.12 KPI38373.1 - 2.4e-48 164.3 0.0 2.9e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.6 KPI38374.1 - 2.9e-32 110.8 0.2 2.9e-32 110.8 0.1 2.5 3 0 0 3 3 3 1 STAG domain HEAT_2 PF13646.1 KPI38374.1 - 6.7e-06 26.2 0.0 0.4 10.9 0.0 3.9 2 1 1 3 3 3 2 HEAT repeats GFA PF04828.9 KPI38375.1 - 5.5e-15 55.0 8.7 2.3e-07 30.6 3.1 3.4 2 2 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.11 KPI38376.1 - 3.5e-51 173.9 17.5 2.3e-45 154.8 4.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI38376.1 - 6.6e-14 51.3 4.1 6.6e-14 51.3 2.9 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1673 PF07895.6 KPI38376.1 - 0.0084 15.6 2.4 0.014 14.9 0.6 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1673) OATP PF03137.15 KPI38376.1 - 0.0086 14.1 1.2 1 7.3 0.9 2.4 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF3353 PF11833.3 KPI38376.1 - 0.17 11.3 4.1 0.57 9.6 2.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) DEAD PF00270.24 KPI38378.1 - 3.7e-24 85.0 0.0 7.3e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 KPI38378.1 - 2.6e-12 47.1 0.3 6.8e-12 45.7 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 KPI38378.1 - 1.5e-09 37.6 0.0 4.3e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.6 KPI38378.1 - 0.00036 20.5 0.0 0.0009 19.2 0.0 1.7 1 0 0 1 1 1 1 DNA replication factor CDT1 like Ebp2 PF05890.7 KPI38379.1 - 4.7e-82 275.3 12.7 4.7e-82 275.3 8.8 2.4 1 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 MARVEL PF01284.18 KPI38380.1 - 1.1e-15 57.7 14.1 1.3e-15 57.4 9.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF308 PF03729.8 KPI38380.1 - 0.029 14.3 8.7 1.2 9.2 0.0 3.0 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF202 PF02656.10 KPI38380.1 - 0.044 13.9 6.7 1.2 9.4 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Abi PF02517.11 KPI38380.1 - 5.6 7.1 9.8 22 5.2 6.8 1.9 1 1 0 1 1 1 0 CAAX protease self-immunity DUF4282 PF14110.1 KPI38380.1 - 8.1 6.7 9.5 8.3 6.6 2.8 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) DUF4131 PF13567.1 KPI38380.1 - 8.3 5.7 14.0 7.5 5.9 5.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) TauD PF02668.11 KPI38381.1 - 4.4e-29 101.9 0.0 5.9e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KPI38381.1 - 0.079 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 CsiD AP3B1_C PF14796.1 KPI38381.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal RIO1 PF01163.17 KPI38382.1 - 8.5e-43 145.9 0.0 1.4e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 KPI38382.1 - 1.3e-29 102.0 0.0 2.4e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 KPI38382.1 - 4.6e-06 26.5 1.9 0.024 14.3 0.2 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KPI38382.1 - 0.00057 19.0 0.2 0.086 11.8 0.1 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family UBX PF00789.15 KPI38383.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 UBX domain UPF0444 PF15475.1 KPI38383.1 - 0.034 14.2 2.0 0.082 12.9 1.4 1.6 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 Hamartin PF04388.7 KPI38383.1 - 0.55 8.8 10.0 0.93 8.0 7.0 1.4 1 0 0 1 1 1 0 Hamartin protein PRP1_N PF06424.7 KPI38383.1 - 1.1 9.6 12.6 0.24 11.7 2.0 2.4 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF515 PF04415.7 KPI38383.1 - 3.7 5.6 7.9 8.1 4.5 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Hex_IIIa PF02455.11 KPI38383.1 - 6.5 5.3 11.6 12 4.4 8.0 1.4 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) PRCC PF10253.4 KPI38383.1 - 9 6.9 28.1 0.09 13.4 10.6 3.1 3 0 0 3 3 3 0 Mitotic checkpoint regulator, MAD2B-interacting Polysacc_deac_1 PF01522.16 KPI38384.1 - 2.3e-12 46.6 0.0 4.2e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase SURF1 PF02104.10 KPI38385.1 - 6.8e-32 111.0 0.0 7.5e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 SURF1 family Synaptobrevin PF00957.16 KPI38386.1 - 4.7e-32 109.4 0.0 6.4e-32 109.0 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KPI38386.1 - 5.3e-23 80.3 0.1 8.9e-23 79.6 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain SpoIIAA-like PF11964.3 KPI38386.1 - 0.063 13.5 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 SpoIIAA-like DUF2275 PF10039.4 KPI38386.1 - 0.14 12.0 0.4 10 5.9 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2275) DUF2628 PF10947.3 KPI38386.1 - 0.3 10.8 1.8 0.59 9.9 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) PI3Ka PF00613.15 KPI38387.1 - 1.3e-50 171.1 0.1 2.2e-50 170.4 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KPI38387.1 - 1.9e-42 145.3 0.0 1.6e-40 139.0 0.0 2.9 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 KPI38387.1 - 6e-29 100.6 0.0 1.1e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Sulfatase PF00884.18 KPI38388.1 - 1.1e-39 136.4 0.0 1.7e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase MFS_1 PF07690.11 KPI38388.1 - 3.8e-23 81.7 23.8 5.1e-23 81.3 16.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF791 PF05631.9 KPI38388.1 - 0.022 13.4 0.3 0.054 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF791) DUF3425 PF11905.3 KPI38389.1 - 1.3e-20 73.7 0.1 2.8e-20 72.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KPI38389.1 - 2.5e-05 24.1 4.5 4e-05 23.4 3.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor CASP_C PF08172.7 KPI38389.1 - 0.042 12.8 0.1 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 CASP C terminal Rap1_C PF11626.3 KPI38389.1 - 7.5 6.5 7.9 1 9.3 2.1 2.2 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Mpv17_PMP22 PF04117.7 KPI38390.1 - 7.9e-13 47.8 1.0 2.5e-11 43.0 0.5 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family NADH_oxidored PF08040.6 KPI38390.1 - 0.067 12.8 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 MNLL subunit UPF0154 PF03672.8 KPI38390.1 - 0.13 11.8 0.1 0.51 9.9 0.0 2.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) WD40 PF00400.27 KPI38391.1 - 0.0026 17.5 0.8 0.011 15.6 0.2 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat FAD_binding_3 PF01494.14 KPI38392.1 - 1.6e-19 70.2 0.0 3.4e-19 69.1 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI38392.1 - 0.0001 21.3 0.2 0.012 14.5 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KPI38392.1 - 0.00011 21.2 0.0 0.019 13.9 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 KPI38392.1 - 0.0004 20.3 0.1 0.0011 18.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KPI38392.1 - 0.0054 15.8 0.1 0.044 12.8 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 KPI38392.1 - 0.017 13.7 0.4 0.51 8.8 0.0 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Cas6 PF09559.5 KPI38392.1 - 0.075 12.7 0.2 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 Cas6 Crispr AlaDh_PNT_C PF01262.16 KPI38392.1 - 0.091 12.3 0.1 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KPI38392.1 - 0.11 12.5 0.0 0.38 10.7 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI38392.1 - 0.65 8.7 6.4 0.25 10.1 1.3 2.3 2 1 1 3 3 3 0 FAD binding domain HA2 PF04408.18 KPI38394.1 - 1.2e-19 70.2 0.0 4.4e-19 68.3 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KPI38394.1 - 3.7e-15 55.7 0.0 1.1e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KPI38394.1 - 4.2e-13 48.9 0.1 1.2e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KPI38394.1 - 8.7e-09 35.0 0.2 3.1e-08 33.2 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.17 KPI38394.1 - 1.5e-08 34.4 0.0 5.1e-08 32.8 0.0 2.0 1 0 0 1 1 1 1 RWD domain AAA_22 PF13401.1 KPI38394.1 - 8.8e-06 25.8 0.1 3.4e-05 23.9 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KPI38394.1 - 9.2e-05 21.8 0.1 0.00045 19.6 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain KaiC PF06745.8 KPI38394.1 - 0.00054 19.1 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 KaiC UBA PF00627.26 KPI38394.1 - 0.00071 19.3 0.0 0.041 13.7 0.2 2.7 2 0 0 2 2 2 1 UBA/TS-N domain DND1_DSRM PF14709.1 KPI38394.1 - 0.0019 18.4 0.0 0.0056 16.9 0.0 1.8 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_25 PF13481.1 KPI38394.1 - 0.0033 16.8 0.0 0.0091 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KPI38394.1 - 0.0093 15.4 0.0 0.021 14.2 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SE PF00437.15 KPI38394.1 - 0.012 14.5 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 KPI38394.1 - 0.03 14.6 0.5 0.03 14.6 0.4 2.1 2 1 0 2 2 2 0 AAA domain Zot PF05707.7 KPI38394.1 - 0.031 13.7 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_19 PF13245.1 KPI38394.1 - 0.053 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Neurensin PF14927.1 KPI38395.1 - 0.057 12.8 0.3 0.17 11.2 0.0 1.9 1 1 1 2 2 2 0 Neurensin ADH_N PF08240.7 KPI38396.1 - 2.9e-23 81.7 1.0 5.1e-23 80.9 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI38396.1 - 9.4e-19 67.2 0.4 1.5e-18 66.6 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KPI38396.1 - 0.0014 17.8 0.0 0.0026 16.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 KPI38396.1 - 0.018 15.9 0.0 0.032 15.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 KPI38396.1 - 0.023 15.1 0.0 0.071 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF849 PF05853.7 KPI38396.1 - 0.028 13.2 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) TrkA_N PF02254.13 KPI38396.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_18 PF12847.2 KPI38396.1 - 0.082 13.4 0.1 0.44 11.1 0.1 2.2 2 1 0 2 2 2 0 Methyltransferase domain Thg1C PF14413.1 KPI38398.1 - 4.3e-51 171.6 0.2 6.2e-51 171.1 0.1 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KPI38398.1 - 3.5e-43 146.4 0.0 5.8e-43 145.7 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Gal-3-0_sulfotr PF06990.6 KPI38398.1 - 0.035 12.7 0.1 0.086 11.4 0.0 1.6 2 0 0 2 2 2 0 Galactose-3-O-sulfotransferase Cyclin_N PF00134.18 KPI38399.1 - 4.3e-43 145.8 0.7 7.5e-43 145.1 0.5 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KPI38399.1 - 3.4e-31 107.6 0.1 7.7e-31 106.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Mem_trans PF03547.13 KPI38400.1 - 2.9e-54 183.8 2.2 3.6e-54 183.5 1.5 1.1 1 0 0 1 1 1 1 Membrane transport protein CMAS PF02353.15 KPI38401.1 - 3.1e-14 52.6 0.0 5.9e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KPI38401.1 - 6e-13 48.8 0.0 1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI38401.1 - 1.1e-10 41.3 0.0 1.7e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KPI38401.1 - 4.7e-10 39.8 0.1 1.1e-05 25.8 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KPI38401.1 - 1.1e-08 35.5 0.0 2.9e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI38401.1 - 6.1e-08 33.0 0.1 8.2e-06 26.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI38401.1 - 2e-06 28.1 0.0 6.9e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI38401.1 - 0.00014 21.8 0.0 0.00045 20.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KPI38401.1 - 0.0076 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.7 KPI38401.1 - 0.0076 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 KPI38401.1 - 0.025 13.9 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Glyco_hydro_2_N PF02837.13 KPI38402.1 - 3e-53 179.8 1.9 4e-53 179.3 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KPI38402.1 - 1.3e-05 25.5 0.0 4e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 Stn1 PF10451.4 KPI38403.1 - 1e-09 37.6 0.0 1.6e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 KPI38403.1 - 0.041 13.7 0.0 0.24 11.3 0.0 2.2 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain DUF334 PF03904.8 KPI38403.1 - 1.8 7.8 6.3 2.1 7.6 3.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF334) adh_short PF00106.20 KPI38404.1 - 1.6e-25 89.9 0.0 2.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI38404.1 - 1.3e-13 51.3 0.0 3e-13 50.1 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI38404.1 - 8.9e-08 32.0 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI38404.1 - 1.8e-07 31.3 0.0 7.8e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KPI38404.1 - 0.0013 18.4 0.2 0.0029 17.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KPI38404.1 - 0.0047 16.3 0.0 0.0067 15.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KPI38404.1 - 0.016 14.4 0.0 0.06 12.5 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family ADH_zinc_N PF00107.21 KPI38404.1 - 0.046 13.2 0.1 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.12 KPI38404.1 - 0.085 11.7 0.0 0.14 10.9 0.0 1.3 1 1 0 1 1 1 0 RmlD substrate binding domain DUF1776 PF08643.5 KPI38404.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) CoA_transf_3 PF02515.12 KPI38406.1 - 7.4e-32 110.1 0.0 5.9e-31 107.1 0.0 2.1 2 0 0 2 2 2 1 CoA-transferase family III GST_N_3 PF13417.1 KPI38407.1 - 1.4e-18 66.8 0.1 3.1e-18 65.7 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI38407.1 - 3.5e-15 55.7 0.1 8.2e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KPI38407.1 - 4.7e-09 36.2 0.0 1.7e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 KPI38407.1 - 0.00014 21.7 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.20 KPI38407.1 - 0.021 14.7 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI38407.1 - 0.023 14.5 0.1 0.042 13.7 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FMN_red PF03358.10 KPI38408.1 - 6e-30 103.7 0.0 7.7e-30 103.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KPI38408.1 - 3.5e-07 29.9 0.0 5.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold MAS20 PF02064.10 KPI38409.1 - 2e-16 59.9 0.4 8.5e-16 57.9 0.3 1.8 1 1 0 1 1 1 1 MAS20 protein import receptor DUF2215 PF10225.4 KPI38409.1 - 0.026 13.9 0.2 0.033 13.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) PsbN PF02468.10 KPI38409.1 - 0.043 13.4 1.8 0.076 12.6 1.3 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) AMP-binding PF00501.23 KPI38410.1 - 1e-81 274.5 0.0 1.3e-81 274.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI38410.1 - 4.1e-11 43.6 0.5 2.1e-10 41.3 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 KPI38411.1 - 3e-12 46.7 0.0 8.8e-12 45.2 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI38411.1 - 1.6e-06 27.9 0.0 4.3e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KPI38411.1 - 0.018 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase ELFV_dehydrog PF00208.16 KPI38411.1 - 0.023 14.2 0.1 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Arylsulfotran_2 PF14269.1 KPI38412.1 - 4.2e-48 164.0 1.7 5.2e-48 163.7 1.2 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KPI38412.1 - 1.5e-19 69.8 0.4 3.7e-19 68.5 0.3 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DBR1 PF05011.8 KPI38413.1 - 1.1e-48 164.8 0.2 3.7e-48 163.0 0.0 2.0 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KPI38413.1 - 4.9e-09 35.8 1.6 8.1e-09 35.1 1.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PAM2 PF07145.10 KPI38413.1 - 0.077 12.5 0.0 4.6 6.9 0.0 2.6 2 0 0 2 2 2 0 Ataxin-2 C-terminal region DIOX_N PF14226.1 KPI38414.1 - 5.5e-18 65.5 0.1 1.3e-17 64.3 0.1 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI38414.1 - 0.0012 19.1 0.1 0.0027 17.9 0.1 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Caleosin PF05042.8 KPI38415.1 - 4.6e-40 137.0 0.0 6.2e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_8 PF13833.1 KPI38415.1 - 0.00017 21.1 0.8 0.0037 16.8 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KPI38415.1 - 0.011 15.0 0.5 0.078 12.3 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 KPI38415.1 - 0.12 12.3 1.2 0.54 10.2 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain HAD PF12710.2 KPI38417.1 - 6.4e-05 23.1 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KPI38417.1 - 0.00044 20.7 0.0 0.00072 20.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1241 PF06840.6 KPI38417.1 - 0.017 14.3 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Hydrolase_3 PF08282.7 KPI38417.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Vps51 PF08700.6 KPI38418.1 - 1.6e-14 53.5 2.1 1.6e-14 53.5 1.4 2.5 3 0 0 3 3 3 1 Vps51/Vps67 Sec5 PF15469.1 KPI38418.1 - 0.00053 19.7 1.2 0.15 11.7 0.3 2.6 2 0 0 2 2 2 2 Exocyst complex component Sec5 DUF2205 PF10224.4 KPI38418.1 - 0.036 13.6 1.2 0.14 11.7 0.2 2.5 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Zn_clus PF00172.13 KPI38419.1 - 9e-06 25.5 11.5 1.8e-05 24.5 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KPI38420.1 - 9.5e-50 169.2 0.2 1.8e-49 168.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.16 KPI38422.1 - 2.3e-90 303.2 40.9 1e-89 301.0 28.4 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI38422.1 - 1.5e-16 59.9 42.9 6.4e-16 57.9 29.7 1.8 1 1 0 1 1 1 1 Amino acid permease DUF997 PF06196.7 KPI38422.1 - 8.6 5.9 10.5 0.26 10.8 1.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF997) 4HBT PF03061.17 KPI38424.1 - 4.7e-10 39.4 0.0 7.2e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 KPI38424.1 - 0.0004 20.8 0.0 0.00047 20.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 KPI38424.1 - 0.001 18.0 0.1 0.0021 17.0 0.1 1.4 2 0 0 2 2 2 1 Acyl-ACP thioesterase MMR_HSR1 PF01926.18 KPI38425.1 - 1.7e-06 27.9 0.8 3.7e-06 26.8 0.0 2.1 2 2 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KPI38425.1 - 0.006 15.7 0.0 0.02 14.0 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KPI38425.1 - 0.014 15.1 0.0 0.014 15.1 0.0 3.9 2 2 1 3 3 2 0 Dynamin family DUF1409 PF07197.7 KPI38425.1 - 0.027 14.5 0.4 0.027 14.5 0.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1409) AAA_18 PF13238.1 KPI38425.1 - 0.066 13.5 0.0 0.066 13.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF4364 PF14277.1 KPI38425.1 - 0.17 11.4 9.1 1.9 8.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) ABC_tran PF00005.22 KPI38425.1 - 0.37 11.0 0.0 0.37 11.0 0.0 2.9 2 1 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 KPI38425.1 - 0.39 11.5 2.7 0.92 10.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain IFT57 PF10498.4 KPI38425.1 - 2.6 6.6 21.6 23 3.6 14.8 2.0 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2730 PF10805.3 KPI38425.1 - 2.7 7.7 9.1 1.4 8.6 3.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF4407 PF14362.1 KPI38425.1 - 6.3 5.6 15.8 9.2 5.1 11.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IL1 PF00340.14 KPI38426.1 - 0.058 12.8 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Interleukin-1 / 18 MFS_1 PF07690.11 KPI38427.1 - 5.8e-16 58.1 30.1 5.8e-16 58.1 20.9 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4389 PF14333.1 KPI38427.1 - 0.16 11.6 3.0 2.2 8.0 0.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4389) ThiF PF00899.16 KPI38428.1 - 1.8e-52 176.7 0.0 1.4e-31 109.1 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 KPI38428.1 - 2.2e-39 132.8 4.2 1.7e-25 88.3 0.3 2.7 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 KPI38428.1 - 1.8e-37 128.2 0.0 3.7e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 KPI38428.1 - 3.7e-26 90.2 2.2 1.1e-21 75.9 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site DUF3317 PF11779.3 KPI38429.1 - 3.8e-17 61.4 2.2 5.8e-17 60.8 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) WD40 PF00400.27 KPI38430.1 - 7e-41 136.6 27.4 1.9e-08 33.8 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KPI38430.1 - 0.0082 15.6 0.0 13 5.4 0.0 4.3 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain CortBP2 PF09727.4 KPI38430.1 - 0.2 11.1 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Cortactin-binding protein-2 DUF2264 PF10022.4 KPI38431.1 - 5.2e-121 403.6 0.3 1.5e-120 402.1 0.2 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) LSM PF01423.17 KPI38432.1 - 3e-15 55.4 0.1 3.7e-15 55.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain CRCB PF02537.10 KPI38433.1 - 4.5e-35 120.0 12.3 4.2e-22 78.2 3.2 2.6 2 0 0 2 2 2 2 CrcB-like protein YqzE PF14038.1 KPI38434.1 - 0.068 12.9 0.3 0.068 12.9 0.2 4.4 5 0 0 5 5 5 0 YqzE-like protein TRF PF08558.5 KPI38437.1 - 0.00011 21.6 0.0 0.00015 21.2 0.0 1.1 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) ADH_zinc_N_2 PF13602.1 KPI38438.1 - 1.4e-11 45.3 0.2 3.3e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI38438.1 - 0.017 14.8 0.0 0.065 13.0 0.0 1.9 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain F-box-like PF12937.2 KPI38439.1 - 0.003 17.2 0.1 0.0063 16.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF1956 PF09209.6 KPI38439.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1956) ECH PF00378.15 KPI38440.1 - 1.2e-25 90.0 0.1 1.5e-25 89.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DAO PF01266.19 KPI38441.1 - 1.5e-63 214.8 0.2 2.2e-63 214.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 KPI38441.1 - 5.3e-56 189.3 0.0 1.1e-55 188.3 0.0 1.5 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KPI38441.1 - 2.8e-17 62.5 0.1 6.3e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 KPI38441.1 - 1.1e-07 31.7 0.0 1e-05 25.4 0.0 2.9 2 1 1 3 3 3 1 Sarcosine oxidase, gamma subunit family Pyr_redox PF00070.22 KPI38441.1 - 0.00013 22.2 0.6 0.033 14.5 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI38441.1 - 0.00036 20.6 0.0 0.001 19.1 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI38441.1 - 0.001 18.8 0.2 0.06 13.1 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KPI38441.1 - 0.0015 17.2 0.1 0.022 13.3 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase TrkA_N PF02254.13 KPI38441.1 - 0.0024 17.8 0.0 0.0066 16.4 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain ThiF PF00899.16 KPI38441.1 - 0.0025 17.6 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 ThiF family NAD_binding_8 PF13450.1 KPI38441.1 - 0.02 14.9 0.0 0.062 13.3 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI38441.1 - 0.024 14.5 0.3 0.14 12.0 0.1 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KPI38441.1 - 0.045 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KPI38441.1 - 0.053 12.5 0.9 0.26 10.2 0.6 2.0 1 1 0 1 1 1 0 FAD binding domain Pmp3 PF01679.12 KPI38442.1 - 3e-21 74.8 5.7 3.8e-21 74.5 4.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator MFS_1 PF07690.11 KPI38443.1 - 3e-34 118.2 54.2 2.7e-19 69.1 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI38443.1 - 0.00022 19.9 12.1 0.00022 19.9 8.4 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter SpoVAB PF13782.1 KPI38443.1 - 7.6 6.5 17.7 0.27 11.2 2.7 3.6 2 1 1 3 3 3 0 Stage V sporulation protein AB MoCF_biosynth PF00994.19 KPI38444.1 - 4.7e-55 184.9 0.1 7.1e-28 96.8 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KPI38444.1 - 1.3e-32 112.4 2.0 1.9e-32 111.8 1.4 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KPI38444.1 - 9e-17 60.8 0.0 2.9e-16 59.1 0.0 2.0 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Zip PF02535.17 KPI38444.1 - 0.76 8.7 3.8 1.2 8.0 2.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 KPI38444.1 - 7.6 5.2 10.1 1.3 7.8 4.2 1.6 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Aminotran_5 PF00266.14 KPI38447.1 - 6.4e-20 71.2 0.0 3.1e-19 68.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V ubiquitin PF00240.18 KPI38448.1 - 1.4e-16 59.6 0.0 2.5e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KPI38448.1 - 5.5e-08 32.3 0.1 1.2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 KPI38448.1 - 0.068 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Telomere stability and silencing Polysacc_deac_1 PF01522.16 KPI38449.1 - 7e-10 38.6 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Dak1 PF02733.12 KPI38450.1 - 1.4e-109 365.6 2.2 1.9e-109 365.2 1.6 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KPI38450.1 - 1.4e-45 155.1 2.0 1.4e-45 155.1 1.4 2.2 3 0 0 3 3 3 1 DAK2 domain zf-ZPR1 PF03367.8 KPI38452.1 - 2e-97 322.8 0.0 1.7e-49 167.0 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zf-ribbon_3 PF13248.1 KPI38452.1 - 1.8 7.9 5.6 4.9 6.4 0.9 2.8 2 1 0 2 2 2 0 zinc-ribbon domain zf-ISL3 PF14690.1 KPI38452.1 - 2.1 8.4 5.0 26 4.9 0.6 3.2 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 UPF0547 PF10571.4 KPI38452.1 - 2.6 7.8 12.2 1.7 8.4 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.7 KPI38452.1 - 3.3 7.5 5.6 0.31 10.8 0.3 2.0 3 0 0 3 3 3 0 zinc-ribbons E7 PF00527.13 KPI38452.1 - 6.6 6.9 11.2 1.2 9.3 0.1 3.6 3 1 0 3 3 3 0 E7 protein, Early protein Arb1 PF09692.5 KPI38453.1 - 1.4e-96 323.7 0.0 1.8e-96 323.4 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Acetyltransf_3 PF13302.1 KPI38454.1 - 7.1e-12 45.6 0.0 1.1e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KPI38454.1 - 0.00065 19.6 0.0 0.044 13.7 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KPI38454.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain TMEM154 PF15102.1 KPI38455.1 - 0.00071 19.2 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family CD99L2 PF12301.3 KPI38455.1 - 0.0033 17.1 5.3 0.56 9.8 2.8 2.3 1 1 1 2 2 2 2 CD99 antigen like protein 2 AAA_27 PF13514.1 KPI38455.1 - 0.023 12.4 3.4 0.029 12.0 2.3 1.1 1 0 0 1 1 1 0 AAA domain DUF2956 PF11169.3 KPI38455.1 - 0.026 14.4 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DAG1 PF05454.6 KPI38455.1 - 0.04 13.1 0.0 0.067 12.3 0.0 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Herpes_gE PF02480.11 KPI38455.1 - 0.04 12.1 0.0 0.053 11.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4366 PF14283.1 KPI38455.1 - 0.052 12.9 0.0 0.066 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CcmH PF03918.9 KPI38455.1 - 0.071 12.0 0.2 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF4381 PF14316.1 KPI38455.1 - 0.09 12.8 3.9 6 6.9 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4381) Vps5 PF09325.5 KPI38455.1 - 0.092 11.9 0.4 0.27 10.4 0.3 1.7 1 1 0 1 1 1 0 Vps5 C terminal like TarH PF02203.10 KPI38455.1 - 8.2 6.2 8.2 77 3.0 5.1 2.6 2 1 0 2 2 2 0 Tar ligand binding domain homologue OHCU_decarbox PF09349.5 KPI38456.1 - 1e-39 136.3 0.1 1.3e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase HHH_5 PF14520.1 KPI38456.1 - 0.0047 17.0 0.1 0.63 10.2 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix domain GFA PF04828.9 KPI38458.1 - 3.2e-06 26.9 0.0 4.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 KPI38458.1 - 0.014 14.8 0.3 0.027 13.9 0.2 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.1 KPI38458.1 - 0.072 12.3 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain p450 PF00067.17 KPI38459.1 - 8.4e-63 212.4 0.0 2.4e-62 210.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Rot1 PF10681.4 KPI38460.1 - 7.5e-80 267.2 0.0 1e-79 266.8 0.0 1.2 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal F-box-like_2 PF13013.1 KPI38461.1 - 0.0047 16.6 0.2 0.018 14.7 0.0 2.0 2 0 0 2 2 2 1 F-box-like domain Thioredoxin PF00085.15 KPI38462.1 - 4.7e-64 212.6 0.1 1.1e-32 111.8 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 KPI38462.1 - 1.5e-20 73.4 0.1 1.3e-08 35.0 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin-like domain ERp29 PF07749.7 KPI38462.1 - 5.6e-18 65.3 0.2 2e-17 63.5 0.0 2.0 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_7 PF13899.1 KPI38462.1 - 9.6e-15 54.3 0.0 3.2e-06 27.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KPI38462.1 - 1e-13 51.1 0.0 7.6e-06 25.9 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 KPI38462.1 - 8.6e-10 38.3 0.1 0.0015 18.2 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 KPI38462.1 - 2.5e-07 30.3 0.2 0.0039 16.7 0.0 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.1 KPI38462.1 - 5e-07 29.6 0.0 0.0066 16.2 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_9 PF14595.1 KPI38462.1 - 0.00012 21.6 0.0 0.42 10.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_4 PF13462.1 KPI38462.1 - 0.00084 19.3 3.7 3.5 7.6 0.0 4.2 2 2 3 5 5 5 2 Thioredoxin Glutaredoxin PF00462.19 KPI38462.1 - 0.031 14.2 0.4 9.9 6.2 0.0 3.0 2 1 0 2 2 2 0 Glutaredoxin HyaE PF07449.6 KPI38462.1 - 0.074 12.9 0.0 0.37 10.7 0.0 2.2 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DDE_Tnp_1_2 PF13586.1 KPI38462.1 - 0.094 12.9 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain PPR_2 PF13041.1 KPI38463.1 - 2.6e-56 187.3 7.8 5e-12 45.6 0.0 13.1 11 3 4 15 15 15 9 PPR repeat family PPR PF01535.15 KPI38463.1 - 2.3e-33 111.8 14.5 0.00049 19.8 0.1 14.2 15 1 0 15 15 15 7 PPR repeat PPR_3 PF13812.1 KPI38463.1 - 4.3e-31 104.5 25.8 0.0059 16.7 0.0 15.9 15 3 3 18 18 18 7 Pentatricopeptide repeat domain PPR_1 PF12854.2 KPI38463.1 - 1.6e-25 88.2 4.9 3.3e-07 29.6 0.0 11.2 10 1 0 10 10 10 5 PPR repeat Clathrin PF00637.15 KPI38463.1 - 0.00012 21.7 0.3 0.0045 16.6 0.0 2.8 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_7 PF13176.1 KPI38463.1 - 0.041 13.7 7.0 0.91 9.4 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3368 PF11848.3 KPI38463.1 - 0.082 12.4 0.0 0.42 10.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) TPR_19 PF14559.1 KPI38463.1 - 4.5 7.6 22.8 0.14 12.4 1.3 6.7 7 1 1 8 8 8 0 Tetratricopeptide repeat RRM_1 PF00076.17 KPI38464.1 - 2e-20 72.2 0.0 3.9e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI38464.1 - 1.2e-15 57.2 0.0 1.2e-06 28.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Gon7 PF08738.5 KPI38464.1 - 0.35 10.8 2.7 2.1 8.4 0.4 2.5 2 0 0 2 2 2 0 Gon7 family BCDHK_Adom3 PF10436.4 KPI38465.1 - 2.3e-68 228.8 0.0 3.2e-68 228.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KPI38465.1 - 1.9e-14 53.3 0.0 8.2e-14 51.2 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sorb PF02208.11 KPI38465.1 - 0.013 14.8 0.0 0.039 13.3 0.0 1.8 2 0 0 2 2 2 0 Sorbin homologous domain HATPase_c_3 PF13589.1 KPI38465.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.12 KPI38465.1 - 0.15 11.4 0.1 3 7.2 0.0 2.3 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family Pkinase PF00069.20 KPI38466.1 - 1.1e-46 159.1 0.0 3.2e-45 154.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI38466.1 - 4.9e-28 97.9 0.0 3e-27 95.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 KPI38466.1 - 0.0012 17.7 0.1 0.002 17.0 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 KPI38466.1 - 0.0053 15.7 0.0 0.0085 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Sec_GG PF07549.9 KPI38466.1 - 0.046 12.9 0.2 0.12 11.6 0.1 1.8 1 0 0 1 1 1 0 SecD/SecF GG Motif Pox_ser-thr_kin PF05445.6 KPI38466.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 KPI38466.1 - 0.15 11.7 0.0 0.45 10.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3328 PF11807.3 KPI38467.1 - 1.6e-49 168.5 2.3 2e-49 168.2 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RNA_pol_A_bac PF01000.21 KPI38469.1 - 3.6e-06 27.1 0.0 8.4e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain tRNA_int_endo PF01974.12 KPI38471.1 - 1.9e-12 46.7 0.0 3.8e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain HAUS6_N PF14661.1 KPI38471.1 - 0.17 11.2 1.8 0.24 10.7 1.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4385 PF14328.1 KPI38473.1 - 3e-47 160.1 0.4 5e-47 159.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) DUF3433 PF11915.3 KPI38474.1 - 8.3e-33 112.4 26.0 2e-18 66.3 1.7 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) PrgI PF12666.2 KPI38474.1 - 0.71 10.0 6.4 0.37 10.9 1.5 2.7 2 0 0 2 2 2 0 PrgI family protein GMC_oxred_N PF00732.14 KPI38475.1 - 9e-53 179.3 0.0 2.6e-50 171.2 0.0 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI38475.1 - 2.9e-30 105.4 0.0 4.8e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KPI38475.1 - 0.00067 18.6 0.0 0.00097 18.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KPI38475.1 - 0.0018 17.1 0.0 0.62 8.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KPI38475.1 - 0.025 14.6 0.0 0.067 13.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI38475.1 - 0.029 13.2 0.0 0.35 9.7 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KPI38475.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KPI38475.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI38475.1 - 0.084 11.9 0.1 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KPI38475.1 - 0.23 9.8 0.1 0.88 7.9 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein ATP_bind_1 PF03029.12 KPI38477.1 - 1.6e-63 214.4 0.0 2.1e-62 210.8 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KPI38477.1 - 0.00058 20.6 0.0 0.0018 19.0 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_31 PF13614.1 KPI38477.1 - 0.00086 19.2 0.0 0.002 18.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KPI38477.1 - 0.0028 17.5 0.0 0.0056 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KPI38477.1 - 0.003 17.4 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KPI38477.1 - 0.0053 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KPI38477.1 - 0.0068 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KPI38477.1 - 0.0071 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 KPI38477.1 - 0.01 16.0 0.0 0.031 14.4 0.0 1.8 2 0 0 2 2 1 0 RNA helicase UPF0079 PF02367.12 KPI38477.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 KPI38477.1 - 0.013 15.6 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 KPI38477.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.1 KPI38477.1 - 0.031 14.2 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.12 KPI38477.1 - 0.041 13.2 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase CbiA PF01656.18 KPI38477.1 - 0.054 12.8 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SE PF00437.15 KPI38477.1 - 0.055 12.3 0.0 0.095 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PduV-EutP PF10662.4 KPI38477.1 - 0.073 12.5 0.0 0.52 9.7 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 KPI38477.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KPI38477.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.12 KPI38477.1 - 0.077 12.4 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.1 KPI38477.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KPI38477.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 KPI38477.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DENN PF02141.16 KPI38478.1 - 3.7e-40 137.6 0.1 6.1e-40 136.9 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KPI38478.1 - 0.0022 17.9 0.0 0.0057 16.6 0.0 1.8 1 0 0 1 1 1 1 uDENN domain Fork_head PF00250.13 KPI38478.1 - 0.0097 15.9 0.5 0.021 14.8 0.3 1.5 1 0 0 1 1 1 1 Fork head domain GxGYxYP PF14323.1 KPI38478.1 - 0.055 12.1 0.4 0.11 11.2 0.3 1.4 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function DUF3450 PF11932.3 KPI38478.1 - 0.14 11.3 12.1 0.32 10.2 3.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.3 KPI38478.1 - 0.4 10.5 11.8 0.54 10.0 2.2 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KPI38478.1 - 0.74 9.3 19.4 23 4.5 13.4 2.3 1 1 0 1 1 1 0 IncA protein ADIP PF11559.3 KPI38478.1 - 0.86 9.4 16.8 0.43 10.4 5.4 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.3 KPI38478.1 - 0.89 9.2 12.3 5.3 6.8 3.1 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 KPI38478.1 - 1.2 9.0 13.9 0.15 11.9 4.7 2.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 KPI38478.1 - 2.9 7.4 13.7 15 5.1 0.1 3.6 2 1 1 3 3 3 0 Septum formation initiator Fib_alpha PF08702.5 KPI38478.1 - 3.2 7.8 8.5 0.82 9.7 2.6 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 KPI38478.1 - 5.9 5.7 15.8 7.1 5.4 5.4 2.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Acetyltransf_1 PF00583.19 KPI38479.1 - 2e-06 27.7 0.0 2.9e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI38479.1 - 2.5e-06 27.5 0.0 4.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI38479.1 - 1.5e-05 25.0 0.0 4.2e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KPI38479.1 - 7.2e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KPI38479.1 - 0.005 16.6 0.0 0.0081 16.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Cnd3 PF12719.2 KPI38480.1 - 5.7e-41 140.4 1.5 1.4e-38 132.6 0.3 2.9 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KPI38480.1 - 2.6e-11 43.6 14.3 1.8e-06 28.1 2.2 5.2 3 1 3 6 6 6 3 HEAT repeats HEAT PF02985.17 KPI38480.1 - 1.5e-09 37.0 7.0 0.019 15.0 0.0 6.6 6 0 0 6 6 6 4 HEAT repeat Arm PF00514.18 KPI38480.1 - 0.023 14.5 0.3 35 4.4 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KPI38480.1 - 0.17 12.3 19.9 0.5 10.9 1.0 6.7 4 1 2 6 6 6 0 HEAT-like repeat adh_short PF00106.20 KPI38481.1 - 5.7e-10 39.3 0.5 1e-09 38.5 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI38481.1 - 2.2e-05 24.2 0.4 3.6e-05 23.5 0.3 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI38481.1 - 0.0027 17.7 0.1 0.0049 16.9 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KPI38481.1 - 0.042 12.7 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YjeF_N PF03853.10 KPI38481.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Epimerase PF01370.16 KPI38481.1 - 0.089 12.2 0.2 0.76 9.1 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KPI38481.1 - 0.095 12.4 0.1 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 KPI38481.1 - 0.095 12.8 0.1 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_transf_15 PF01793.11 KPI38482.1 - 8e-87 291.2 8.8 9.5e-87 291.0 6.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF2358 PF10184.4 KPI38483.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) DUF2823 PF11034.3 KPI38484.1 - 3.4e-22 78.3 4.0 3.9e-22 78.1 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) HAD_2 PF13419.1 KPI38485.1 - 1.6e-20 74.0 0.0 2.6e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KPI38485.1 - 8.6e-12 45.9 0.0 4.8e-11 43.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KPI38485.1 - 9.9e-10 37.9 0.0 1.3e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 KPI38485.1 - 0.035 14.2 0.0 0.045 13.9 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 KPI38485.1 - 0.038 13.3 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Hydrolase_6 PF13344.1 KPI38485.1 - 0.065 13.1 0.0 0.32 10.9 0.0 2.1 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase zf-C2H2_2 PF12756.2 KPI38485.1 - 0.065 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) WD40 PF00400.27 KPI38487.1 - 0.00017 21.3 9.6 23 5.0 0.1 7.1 8 0 0 8 8 8 2 WD domain, G-beta repeat Lactonase PF10282.4 KPI38487.1 - 0.066 12.2 0.0 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller DNA_pol_B PF00136.16 KPI38488.1 - 1.3e-136 456.1 8.0 9.7e-114 380.6 4.5 2.1 1 1 1 2 2 2 2 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KPI38488.1 - 7.6e-25 87.4 0.5 7.6e-25 87.4 0.3 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KPI38488.1 - 3.4e-23 81.4 3.4 3.4e-23 81.4 2.3 2.1 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 KPI38488.1 - 0.00011 22.0 0.2 0.00044 20.0 0.1 2.0 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 KPI38488.1 - 0.001 18.6 0.1 0.0022 17.5 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.17 KPI38488.1 - 0.0019 17.8 6.7 0.032 13.9 0.6 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) NmrA PF05368.8 KPI38489.1 - 9e-17 61.1 1.0 1.2e-16 60.6 0.7 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI38489.1 - 1.9e-14 54.1 1.6 2.6e-14 53.6 1.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI38489.1 - 0.0022 17.4 0.3 0.033 13.6 0.2 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family YIEGIA PF14045.1 KPI38489.1 - 0.07 11.7 0.1 0.13 10.8 0.1 1.4 1 0 0 1 1 1 0 YIEGIA protein p450 PF00067.17 KPI38490.1 - 8.7e-50 169.5 0.0 1.1e-49 169.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peroxidase_2 PF01328.12 KPI38491.1 - 4.9e-17 61.5 0.0 7e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 AftA_N PF12250.3 KPI38491.1 - 0.013 14.2 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal TRAPPC-Trs85 PF12739.2 KPI38492.1 - 6.9e-98 328.0 0.2 1.2e-97 327.1 0.1 1.4 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_3 PF07720.7 KPI38492.1 - 0.013 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 KPI38492.1 - 0.017 14.9 2.0 0.031 14.1 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat NUC173 PF08161.7 KPI38493.1 - 6.3e-70 234.5 0.0 2.3e-69 232.7 0.0 2.0 2 0 0 2 2 2 1 NUC173 domain HEAT PF02985.17 KPI38493.1 - 3.8e-05 23.4 2.5 0.22 11.6 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat Vac14_Fab1_bd PF12755.2 KPI38493.1 - 0.011 16.1 0.0 37 4.7 0.0 4.1 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Nipped-B_C PF12830.2 KPI38493.1 - 0.033 13.8 0.5 0.25 10.9 0.1 2.7 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus HEAT_2 PF13646.1 KPI38493.1 - 0.82 9.9 10.5 0.097 12.9 0.3 4.5 5 1 0 5 5 5 0 HEAT repeats DUF92 PF01940.11 KPI38495.1 - 2.5e-54 183.8 7.8 3.2e-54 183.4 5.4 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Cyclin_N PF00134.18 KPI38496.1 - 5.2e-11 42.2 1.3 1.2e-10 41.0 0.1 2.1 1 1 1 2 2 2 1 Cyclin, N-terminal domain FixQ PF05545.6 KPI38496.1 - 0.013 15.1 0.1 0.041 13.5 0.0 1.9 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF726 PF05277.7 KPI38497.1 - 2e-124 414.9 1.5 2.8e-124 414.5 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 KPI38497.1 - 0.018 14.7 0.5 0.075 12.7 0.0 2.2 3 0 0 3 3 3 0 Alpha/beta hydrolase family PLDc PF00614.17 KPI38498.1 - 4.5e-17 61.2 1.8 3e-07 30.0 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KPI38498.1 - 8.5e-14 51.3 0.0 4.3e-06 26.5 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain RbcS PF12338.3 KPI38498.1 - 0.0094 15.6 0.2 0.032 14.0 0.1 1.9 1 0 0 1 1 1 1 Ribulose-1,5-bisphosphate carboxylase small subunit FliD_N PF02465.13 KPI38499.1 - 0.013 15.8 9.3 0.26 11.6 1.3 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Homeobox PF00046.24 KPI38500.1 - 1.5e-17 62.9 4.8 3e-17 61.9 3.3 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KPI38500.1 - 0.0005 19.7 1.6 0.0015 18.1 1.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Ndc1_Nup PF09531.5 KPI38500.1 - 1 7.7 3.6 1.5 7.1 2.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ArsB PF02040.10 KPI38501.1 - 1e-14 54.3 22.9 1.4e-10 40.6 6.6 2.3 3 0 0 3 3 3 2 Arsenical pump membrane protein CitMHS PF03600.11 KPI38501.1 - 9e-10 37.6 9.8 9e-10 37.6 6.8 2.1 2 0 0 2 2 2 1 Citrate transporter DUF3774 PF12609.3 KPI38501.1 - 0.31 11.9 3.0 0.5 11.2 2.1 1.3 1 0 0 1 1 1 0 Wound-induced protein DUF3827 PF12877.2 KPI38501.1 - 3.1 5.7 5.3 4.5 5.2 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) RRM_1 PF00076.17 KPI38502.1 - 4.8e-25 86.9 0.0 5.6e-17 61.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI38502.1 - 6.1e-17 61.3 0.0 6.3e-11 42.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI38502.1 - 2.3e-08 33.7 0.0 1.2e-06 28.2 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KPI38502.1 - 0.0028 17.4 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif F1F0-ATPsyn_F PF10791.4 KPI38503.1 - 1.4e-37 127.8 0.4 1.6e-37 127.6 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 KPI38503.1 - 4.9e-07 29.7 0.0 5.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ATP_bind_3 PF01171.15 KPI38504.1 - 1.4e-31 109.3 0.0 2.1e-28 99.0 0.0 2.4 1 1 0 1 1 1 1 PP-loop family SBP_bac_5 PF00496.17 KPI38504.1 - 0.018 13.8 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Ribosomal_S5_C PF03719.10 KPI38505.1 - 2.5e-15 55.5 0.0 4.3e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KPI38505.1 - 2.8e-07 30.1 0.0 5.6e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Sin_N PF04801.8 KPI38506.1 - 5.6e-17 61.7 0.0 1.6e-16 60.2 0.0 1.7 1 1 0 1 1 1 1 Sin-like protein conserved region Pantoate_ligase PF02569.10 KPI38508.1 - 1.7e-76 256.7 0.0 5.3e-76 255.0 0.0 1.7 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Chs3p PF12271.3 KPI38509.1 - 2e-128 427.4 18.1 2.4e-128 427.2 12.5 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit An_peroxidase PF03098.10 KPI38510.1 - 6.1e-93 312.0 0.0 1.7e-72 244.5 0.0 2.3 1 1 1 2 2 2 2 Animal haem peroxidase UQ_con PF00179.21 KPI38510.1 - 9.6e-20 70.4 0.0 2.8e-19 68.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme p450 PF00067.17 KPI38510.1 - 0.0018 16.8 0.0 0.0042 15.6 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 ADH_N PF08240.7 KPI38512.1 - 1.7e-25 88.8 3.1 3.4e-25 87.9 2.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI38512.1 - 8e-19 67.4 0.1 7.5e-18 64.3 0.0 2.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI38512.1 - 0.001 19.9 0.0 0.0019 19.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 KPI38512.1 - 0.089 12.3 0.6 0.21 11.1 0.1 1.7 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 KPI38512.1 - 0.11 11.6 0.1 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-C2H2_4 PF13894.1 KPI38513.1 - 0.00092 19.3 1.5 0.046 14.0 0.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI38513.1 - 0.00097 19.3 3.0 0.021 15.1 0.1 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KPI38513.1 - 0.077 13.1 1.5 12 6.1 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KPI38513.1 - 0.12 12.4 0.8 4.3 7.5 0.4 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FAM75 PF14650.1 KPI38514.1 - 1.4 8.2 4.7 1.8 7.8 3.3 1.1 1 0 0 1 1 1 0 FAM75 family ETC_C1_NDUFA4 PF04800.7 KPI38515.1 - 1.8e-33 114.3 0.2 2.6e-33 113.9 0.1 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF3892 PF13031.1 KPI38515.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3892) 2OG-FeII_Oxy_3 PF13640.1 KPI38516.1 - 2.1e-05 24.9 0.0 6.3e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KPI38516.1 - 0.00027 21.1 0.0 0.00068 19.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3275 PF11679.3 KPI38517.1 - 9.3 5.8 7.8 12 5.4 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DNA_pol_B_exo1 PF03104.14 KPI38518.1 - 1.2e-44 152.5 0.0 1.6e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain Actin PF00022.14 KPI38519.1 - 1.3e-51 175.2 0.0 1.8e-29 102.3 0.0 2.1 2 0 0 2 2 2 2 Actin HTH_32 PF13565.1 KPI38520.1 - 0.0023 18.7 0.4 0.53 11.1 0.0 3.4 3 2 0 3 3 3 1 Homeodomain-like domain DNMT1-RFD PF12047.3 KPI38520.1 - 0.017 14.8 0.8 0.043 13.5 0.0 2.0 2 0 0 2 2 2 0 Cytosine specific DNA methyltransferase replication foci domain HTH_29 PF13551.1 KPI38520.1 - 0.16 12.1 2.9 2.8 8.0 0.0 3.3 4 0 0 4 4 4 0 Winged helix-turn helix Ndc1_Nup PF09531.5 KPI38520.1 - 0.26 9.6 5.2 0.42 8.9 3.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2201_N PF13203.1 KPI38520.1 - 0.79 8.8 14.7 0.016 14.3 3.1 2.4 2 1 1 3 3 3 0 Putative metallopeptidase domain Sds3 PF08598.6 KPI38520.1 - 4.6 6.7 17.4 15 5.0 11.9 2.0 1 1 0 1 1 1 0 Sds3-like GDPD PF03009.12 KPI38521.1 - 2.9e-67 226.8 0.0 5.7e-67 225.9 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 KPI38521.1 - 4.2e-35 119.9 0.0 3.8e-17 62.4 0.0 4.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KPI38521.1 - 1.8e-33 114.3 1.2 3.2e-09 37.0 0.0 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 KPI38521.1 - 1.9e-28 96.8 1.6 8.1e-06 25.3 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat SPX PF03105.14 KPI38521.1 - 2.2e-28 99.8 7.1 8.1e-17 61.8 2.5 3.2 1 1 1 2 2 2 2 SPX domain Ank_5 PF13857.1 KPI38521.1 - 1.4e-25 88.7 0.4 6.3e-10 38.9 0.1 6.2 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI38521.1 - 6.2e-19 66.2 1.0 0.00065 19.6 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat SKN1 PF03935.10 KPI38523.1 - 1.6e-213 709.4 7.4 1.8e-213 709.2 5.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Peptidase_S10 PF00450.17 KPI38525.1 - 4.5e-112 375.2 0.0 6.1e-112 374.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Radical_SAM PF04055.16 KPI38526.1 - 2.4e-09 37.5 0.0 3.5e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KPI38526.1 - 1.6e-06 28.2 0.0 3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KPI38526.1 - 0.00017 21.6 0.0 0.0006 19.8 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain zf-C2H2 PF00096.21 KPI38527.1 - 1.7e-09 37.4 26.5 0.017 15.4 0.4 6.1 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI38527.1 - 5.5e-09 35.7 19.0 0.017 15.4 0.1 6.1 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KPI38527.1 - 3.8e-06 26.9 23.1 2 8.8 0.1 6.6 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KPI38527.1 - 0.00057 19.9 23.3 0.57 10.4 0.1 6.4 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KPI38527.1 - 0.0087 16.1 22.0 0.78 9.8 1.4 4.5 2 2 2 4 4 4 2 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 KPI38527.1 - 0.047 13.2 2.4 10 5.7 0.4 3.4 3 0 0 3 3 3 0 GAGA factor IBR PF01485.16 KPI38527.1 - 0.079 12.8 13.8 0.32 10.8 0.1 3.9 2 1 0 2 2 2 0 IBR domain zf-C2H2_6 PF13912.1 KPI38527.1 - 0.79 9.7 25.2 0.18 11.7 0.4 5.8 6 0 0 6 6 6 0 C2H2-type zinc finger zf-met PF12874.2 KPI38527.1 - 1.9 8.8 0.0 1.9 8.8 0.0 6.3 7 1 0 7 7 6 0 Zinc-finger of C2H2 type DZR PF12773.2 KPI38527.1 - 4.3 7.2 15.8 49 3.8 6.0 3.5 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_4 PF13717.1 KPI38527.1 - 9 6.0 16.3 4.7 6.9 0.0 4.9 6 0 0 6 6 6 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KPI38527.1 - 9.1 5.9 16.8 3.3 7.3 0.0 4.9 6 0 0 6 6 6 0 zinc-ribbon domain Glyco_tranf_2_3 PF13641.1 KPI38528.1 - 4.1e-16 59.4 0.0 5.8e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KPI38528.1 - 2.6e-05 23.9 0.0 4.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KPI38528.1 - 0.0012 18.2 0.0 0.0079 15.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Nucleoplasmin PF03066.10 KPI38528.1 - 0.46 9.9 3.7 4.3 6.8 2.4 2.1 2 0 0 2 2 2 0 Nucleoplasmin DUF4611 PF15387.1 KPI38528.1 - 2 8.5 4.8 14 5.8 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) adh_short_C2 PF13561.1 KPI38529.1 - 4.4e-30 105.2 0.0 5.3e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI38529.1 - 7.3e-25 87.8 0.0 1.4e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI38529.1 - 3.8e-06 26.6 0.0 6.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI38529.1 - 9.4e-05 21.9 0.2 0.00028 20.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KPI38529.1 - 0.00028 20.5 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Urocanase PF01175.13 KPI38529.1 - 0.0037 15.3 0.1 0.0058 14.7 0.0 1.2 1 0 0 1 1 1 1 Urocanase DUF1776 PF08643.5 KPI38529.1 - 0.0041 16.3 0.0 0.0054 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) AdoHcyase_NAD PF00670.16 KPI38529.1 - 0.08 12.7 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KPI38529.1 - 0.082 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KPI38529.1 - 0.13 12.5 0.1 0.28 11.4 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 2OG-FeII_Oxy PF03171.15 KPI38530.1 - 1.7e-13 50.7 0.0 2.5e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KPI38530.1 - 2.3e-13 50.7 0.0 4.3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Rep_fac_C PF08542.6 KPI38531.1 - 2.1e-22 78.9 0.0 7.3e-22 77.1 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KPI38531.1 - 5e-11 42.5 0.0 1.4e-10 41.0 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KPI38531.1 - 2e-07 31.2 0.4 9e-07 29.1 0.0 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KPI38531.1 - 0.00019 21.6 0.9 0.0012 18.9 0.2 2.5 1 1 1 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 KPI38531.1 - 0.0019 18.2 0.1 0.027 14.5 0.1 2.4 1 1 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 KPI38531.1 - 0.016 15.2 2.5 0.18 11.7 0.5 2.6 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 KPI38531.1 - 0.024 14.9 0.0 0.047 13.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 KPI38531.1 - 0.033 13.6 0.2 1.1 8.5 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 KPI38531.1 - 0.034 14.0 0.1 0.11 12.3 0.1 1.8 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 KPI38531.1 - 0.061 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SNF2_N PF00176.18 KPI38531.1 - 0.075 11.8 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Prenyltransf PF01255.14 KPI38531.1 - 0.15 11.1 0.7 0.3 10.1 0.5 1.6 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase 2OG-FeII_Oxy PF03171.15 KPI38532.1 - 1.5e-20 73.3 0.0 2.7e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KPI38532.1 - 2e-19 70.2 0.0 6.1e-19 68.6 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal NUDIX PF00293.23 KPI38534.1 - 8.6e-11 41.6 0.0 1.4e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PTCB-BRCT PF12738.2 KPI38535.1 - 2.8e-39 132.7 2.3 7.1e-18 64.2 0.0 4.8 4 1 0 4 4 4 4 twin BRCT domain BRCT PF00533.21 KPI38535.1 - 2e-29 101.5 0.0 2.7e-09 37.0 0.0 4.4 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain Amidohydro_2 PF04909.9 KPI38536.1 - 1.7e-20 73.7 0.0 9.2e-19 68.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase DUF2183 PF09949.4 KPI38537.1 - 2.2e-33 114.1 0.0 5.1e-33 112.9 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.1 KPI38537.1 - 0.0025 17.8 0.9 0.046 13.7 0.1 3.0 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain DUF605 PF04652.11 KPI38537.1 - 0.9 8.8 33.3 0.13 11.6 15.0 2.2 2 0 0 2 2 2 0 Vta1 like Fungal_trans_2 PF11951.3 KPI38538.1 - 3.4e-08 32.5 0.9 6.2e-08 31.6 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain S6PP PF05116.8 KPI38538.1 - 0.062 12.5 0.3 8.8 5.5 0.0 2.2 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Fcf1 PF04900.7 KPI38539.1 - 2e-09 37.4 1.4 1.6e-06 28.0 1.0 3.3 1 1 0 1 1 1 1 Fcf1 DEAD PF00270.24 KPI38540.1 - 7.3e-40 136.2 0.2 1.1e-39 135.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI38540.1 - 1.2e-19 69.8 0.0 3.2e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KPI38540.1 - 1.4e-18 66.1 0.0 3.1e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KPI38540.1 - 0.018 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit bZIP_1 PF00170.16 KPI38541.1 - 9.4e-08 31.8 9.5 1.1e-07 31.7 4.0 2.3 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KPI38541.1 - 0.0045 16.7 6.4 0.0045 16.7 4.4 2.9 2 1 1 3 3 3 1 Basic region leucine zipper ASD2 PF08687.6 KPI38541.1 - 0.0055 16.0 1.1 0.0086 15.4 0.8 1.3 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 CENP-F_leu_zip PF10473.4 KPI38541.1 - 0.0055 16.5 2.8 0.0075 16.1 1.7 1.3 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Macoilin PF09726.4 KPI38541.1 - 0.0081 14.4 6.7 0.01 14.1 4.6 1.1 1 0 0 1 1 1 1 Transmembrane protein DUF1690 PF07956.6 KPI38541.1 - 0.016 15.2 4.8 0.025 14.5 3.3 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) WD40_alt PF14077.1 KPI38541.1 - 0.021 14.4 0.2 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif TMF_DNA_bd PF12329.3 KPI38541.1 - 0.022 14.5 2.0 0.048 13.4 1.4 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KPI38541.1 - 0.023 14.2 4.7 0.031 13.8 3.2 1.2 1 0 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 KPI38541.1 - 0.023 14.3 3.4 0.049 13.3 2.2 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF2400 PF09674.5 KPI38541.1 - 0.025 14.2 1.8 0.034 13.8 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Shugoshin_N PF07558.6 KPI38541.1 - 0.029 14.0 0.3 0.067 12.9 0.2 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF4618 PF15397.1 KPI38541.1 - 0.029 13.7 1.4 0.04 13.2 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Jnk-SapK_ap_N PF09744.4 KPI38541.1 - 0.045 13.7 4.5 0.072 13.0 3.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6 PF04111.7 KPI38541.1 - 0.048 12.7 3.9 0.064 12.2 2.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 SYCE1 PF15233.1 KPI38541.1 - 0.071 13.0 4.0 0.11 12.4 2.8 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 Baculo_PEP_C PF04513.7 KPI38541.1 - 0.072 12.9 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dad4 PF08650.5 KPI38541.1 - 0.089 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad4 Filo_VP35 PF02097.10 KPI38541.1 - 0.14 11.3 0.1 0.18 10.9 0.1 1.1 1 0 0 1 1 1 0 Filoviridae VP35 DUF4094 PF13334.1 KPI38541.1 - 0.15 12.4 3.6 0.11 12.8 1.3 1.8 2 1 0 2 2 1 0 Domain of unknown function (DUF4094) Pox_A_type_inc PF04508.7 KPI38541.1 - 0.2 11.5 0.1 0.2 11.5 0.1 3.0 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat V_ATPase_I PF01496.14 KPI38541.1 - 0.2 9.4 1.6 0.23 9.2 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlxA PF14282.1 KPI38541.1 - 0.44 10.5 3.8 1.1 9.1 1.2 2.5 1 1 1 2 2 2 0 FlxA-like protein Mnd1 PF03962.10 KPI38541.1 - 0.86 9.2 5.1 1.4 8.5 3.5 1.4 1 1 0 1 1 1 0 Mnd1 family DivIC PF04977.10 KPI38541.1 - 1.7 8.1 4.1 5.5 6.5 0.2 2.2 1 1 1 2 2 2 0 Septum formation initiator bZIP_Maf PF03131.12 KPI38541.1 - 1.9 8.8 15.8 0.28 11.5 6.9 2.4 1 1 1 2 2 2 0 bZIP Maf transcription factor FAM117 PF15388.1 KPI38541.1 - 3.4 6.8 15.1 0.13 11.5 5.9 1.7 1 1 1 2 2 2 0 Protein Family FAM117 PH PF00169.24 KPI38542.1 - 1.2e-21 76.8 0.0 5.1e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KPI38542.1 - 2e-11 44.1 0.1 0.00092 19.4 0.0 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 KPI38542.1 - 2.3e-07 31.0 0.1 0.044 13.9 0.0 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain Ribosomal_L14 PF00238.14 KPI38543.1 - 7.9e-33 112.8 0.0 8.8e-33 112.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Thymidylate_kin PF02223.12 KPI38544.1 - 0.082 12.2 0.0 0.19 11.1 0.0 1.5 2 0 0 2 2 2 0 Thymidylate kinase p450 PF00067.17 KPI38545.1 - 2e-49 168.3 0.0 2.7e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L10 PF00466.15 KPI38547.1 - 1.7e-06 27.8 0.0 2.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 p450 PF00067.17 KPI38548.1 - 5.4e-12 44.9 0.0 7e-12 44.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ran_BP1 PF00638.13 KPI38549.1 - 6e-27 94.1 1.3 9.9e-21 74.0 0.0 2.7 1 1 1 2 2 2 2 RanBP1 domain DUF2076 PF09849.4 KPI38549.1 - 0.0052 16.8 7.3 0.0078 16.3 5.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CDC27 PF09507.5 KPI38549.1 - 0.014 14.6 22.4 0.017 14.3 15.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cwf_Cwc_15 PF04889.7 KPI38549.1 - 0.14 11.8 12.1 0.2 11.3 8.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TSA PF03249.8 KPI38549.1 - 0.19 10.2 4.3 0.28 9.6 3.0 1.2 1 0 0 1 1 1 0 Type specific antigen RXT2_N PF08595.6 KPI38549.1 - 0.21 11.3 3.9 0.35 10.6 2.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Myc_N PF01056.13 KPI38549.1 - 1.5 7.9 14.3 1.9 7.5 9.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region MRP-S31 PF15433.1 KPI38549.1 - 3.8 6.8 11.7 5.3 6.3 8.1 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Pneumo_att_G PF05539.6 KPI38549.1 - 8.1 5.7 10.3 9.7 5.4 7.2 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G WD40 PF00400.27 KPI38550.1 - 1.1e-50 167.7 21.2 2.9e-08 33.2 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KPI38550.1 - 3.2e-05 23.7 0.0 0.072 12.7 0.0 2.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Glyco_hydro_48 PF02011.10 KPI38551.1 - 0.055 11.5 0.0 0.084 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 48 bZIP_1 PF00170.16 KPI38552.1 - 5.6e-08 32.6 7.6 1.7e-07 31.0 5.3 1.8 1 1 0 1 1 1 1 bZIP transcription factor DUF501 PF04417.7 KPI38552.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF501) bZIP_2 PF07716.10 KPI38552.1 - 0.48 10.2 10.2 22 4.9 7.1 2.2 1 1 0 1 1 1 0 Basic region leucine zipper EF-hand_1 PF00036.27 KPI38553.1 - 7.8e-33 109.2 12.7 2e-08 32.9 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KPI38553.1 - 9.3e-29 99.3 5.0 1.6e-14 53.7 0.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KPI38553.1 - 1.4e-26 89.8 5.9 6.2e-09 35.0 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KPI38553.1 - 4e-24 83.9 11.6 9.3e-14 50.7 0.4 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KPI38553.1 - 6.7e-20 69.4 14.1 7e-07 28.3 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KPI38553.1 - 7.1e-12 45.0 0.1 1.4e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 KPI38553.1 - 9.1e-06 25.2 0.0 0.081 12.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.2 KPI38553.1 - 0.00068 19.3 2.1 0.0054 16.4 0.1 2.3 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KPI38553.1 - 0.0014 18.6 0.0 1 9.4 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Toprim_2 PF13155.1 KPI38553.1 - 0.003 17.8 0.4 0.71 10.2 0.0 2.4 1 1 1 2 2 2 1 Toprim-like RNA_pol_Rpb4 PF03874.11 KPI38553.1 - 0.016 15.2 1.1 3.5 7.6 0.2 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb4 TerB PF05099.8 KPI38553.1 - 0.034 13.8 1.6 2.7 7.6 0.2 2.8 1 1 1 2 2 2 0 Tellurite resistance protein TerB SelB-wing_3 PF09107.6 KPI38553.1 - 0.078 12.3 0.0 1.5 8.2 0.0 3.0 3 1 1 4 4 4 0 Elongation factor SelB, winged helix Caleosin PF05042.8 KPI38553.1 - 0.11 12.0 0.1 1.4 8.4 0.0 2.3 1 1 0 1 1 1 0 Caleosin related protein Phi_1 PF04674.7 KPI38553.1 - 0.15 11.1 0.0 0.57 9.3 0.0 1.7 1 1 1 2 2 2 0 Phosphate-induced protein 1 conserved region DUF1014 PF06244.7 KPI38553.1 - 0.18 12.0 0.4 0.71 10.1 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1014) Mito_carr PF00153.22 KPI38554.1 - 1.5e-63 210.5 5.8 3.1e-22 78.0 0.3 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KPI38554.1 - 2.2e-23 82.1 4.6 5.1e-13 48.9 2.2 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KPI38554.1 - 3.5e-21 72.8 4.8 7.7e-07 27.9 0.8 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KPI38554.1 - 5.9e-18 64.2 5.8 3.8e-08 32.8 1.0 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KPI38554.1 - 1.4e-17 61.9 8.6 0.00011 21.7 0.1 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KPI38554.1 - 1.1e-16 59.2 5.9 3.3e-06 26.1 0.8 3.6 3 0 0 3 3 3 3 EF hand SPARC_Ca_bdg PF10591.4 KPI38554.1 - 1.7e-07 31.2 0.7 0.00055 19.9 0.2 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KPI38554.1 - 0.0013 18.4 2.4 0.1 12.3 0.4 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 KPI38554.1 - 0.0049 16.4 2.8 0.87 9.2 0.0 4.0 3 1 1 4 4 4 1 EF hand Ribosomal_L3 PF00297.17 KPI38555.1 - 1.9e-116 388.0 6.3 2.3e-116 387.7 4.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 AIG2 PF06094.7 KPI38556.1 - 1e-05 25.9 0.0 1.5e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 KPI38556.1 - 3.5e-05 23.8 0.0 7.4e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 AIG2-like family adh_short PF00106.20 KPI38557.1 - 2.5e-19 69.8 0.0 3.4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI38557.1 - 1.1e-06 28.4 0.7 4.5e-06 26.4 0.5 1.9 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI38557.1 - 9.1e-06 25.6 0.0 2.1e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KPI38557.1 - 5.3e-05 23.2 1.6 0.00039 20.4 0.1 2.7 2 2 0 3 3 3 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KPI38557.1 - 0.00019 21.1 0.0 0.059 13.1 0.0 2.7 2 0 0 2 2 2 2 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KPI38557.1 - 0.0025 17.2 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HMG_CoA_synt_C PF08540.5 KPI38558.1 - 2.6e-88 296.1 0.3 3.6e-88 295.6 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KPI38558.1 - 7.1e-44 149.4 0.1 1.1e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3783 PF12646.2 KPI38558.1 - 0.027 14.1 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) Mito_carr PF00153.22 KPI38559.1 - 1.2e-30 105.0 1.9 3.3e-19 68.4 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein Rick_17kDa_Anti PF05433.10 KPI38560.1 - 0.006 16.2 14.2 0.006 16.2 9.8 2.1 2 0 0 2 2 2 1 Glycine zipper 2TM domain Transgly_assoc PF04226.8 KPI38560.1 - 0.65 10.1 11.6 1.5 8.9 8.0 1.6 1 0 0 1 1 1 0 Transglycosylase associated protein Med15 PF09606.5 KPI38560.1 - 1.1 7.3 21.0 1.1 7.3 14.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_S10 PF00450.17 KPI38561.1 - 6.8e-63 213.2 2.1 2e-60 205.1 1.4 2.9 1 1 0 1 1 1 1 Serine carboxypeptidase Mhr1 PF12829.2 KPI38562.1 - 2.5e-11 43.2 0.0 8.1e-11 41.6 0.0 1.9 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DUF2291 PF10054.4 KPI38562.1 - 0.7 9.1 5.9 0.28 10.4 1.9 1.8 2 0 0 2 2 2 0 Predicted periplasmic lipoprotein (DUF2291) DUF302 PF03625.9 KPI38563.1 - 4.9e-08 32.4 0.0 7.9e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF302 p450 PF00067.17 KPI38564.1 - 1e-54 185.8 0.0 3.7e-45 154.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF4267 PF14087.1 KPI38565.1 - 4.8e-08 32.5 3.0 6.1e-08 32.2 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) BNR_3 PF13859.1 KPI38565.1 - 0.082 11.9 0.2 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 BNR repeat-like domain DUF3072 PF11272.3 KPI38565.1 - 0.097 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) PGAP1 PF07819.8 KPI38566.1 - 1.7e-07 31.0 0.8 4.1e-05 23.2 0.1 2.4 2 1 0 2 2 2 2 PGAP1-like protein Abhydrolase_5 PF12695.2 KPI38566.1 - 2.4e-07 30.6 0.0 3.7e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KPI38566.1 - 3.6e-06 26.4 0.0 1e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KPI38566.1 - 8.5e-06 25.8 0.0 1.2e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KPI38566.1 - 0.0013 17.8 0.0 0.27 10.2 0.0 2.5 2 1 1 3 3 3 2 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.8 KPI38566.1 - 0.011 15.3 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 KPI38566.1 - 0.035 14.3 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF2305 PF10230.4 KPI38566.1 - 0.051 12.9 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_2 PF02230.11 KPI38566.1 - 0.055 12.9 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 KPI38566.1 - 0.082 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.7 KPI38566.1 - 0.15 11.3 0.1 2.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) GATase PF00117.23 KPI38567.1 - 8e-11 41.7 0.0 1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C12 PF01088.16 KPI38568.1 - 2e-70 236.3 0.0 2.6e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 WD40 PF00400.27 KPI38569.1 - 1.6e-27 94.3 19.6 7.2e-06 25.6 0.1 9.0 9 0 0 9 9 9 5 WD domain, G-beta repeat DAP10 PF07213.6 KPI38570.1 - 0.0006 19.5 0.2 0.0006 19.5 0.1 1.9 2 0 0 2 2 2 1 DAP10 membrane protein SH3_9 PF14604.1 KPI38570.1 - 0.0026 17.2 0.1 0.0055 16.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KPI38570.1 - 0.008 15.5 0.3 0.028 13.7 0.1 1.9 2 0 0 2 2 2 1 SH3 domain RCR PF12273.3 KPI38570.1 - 0.0081 16.7 0.8 0.019 15.5 0.5 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Herpes_gE PF02480.11 KPI38570.1 - 0.011 14.0 0.0 0.017 13.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KPI38570.1 - 0.036 14.4 0.0 0.084 13.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 KPI38570.1 - 0.047 13.2 0.1 0.075 12.6 0.1 1.2 1 0 0 1 1 1 0 IncA protein SKG6 PF08693.5 KPI38570.1 - 0.69 9.2 4.0 1.5 8.2 2.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_1 PF00018.23 KPI38571.1 - 2.7e-06 26.6 0.0 6.9e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KPI38571.1 - 0.0014 18.2 0.2 0.0037 16.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Dak1 PF02733.12 KPI38573.1 - 4.2e-16 58.4 0.0 1.8e-11 43.1 0.0 3.1 2 1 1 3 3 3 3 Dak1 domain GRIP PF01465.15 KPI38575.1 - 5.6e-17 60.9 0.1 1.1e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 GRIP domain YL1_C PF08265.6 KPI38575.1 - 9.1e-14 50.7 0.7 1.6e-13 49.9 0.5 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain IncA PF04156.9 KPI38575.1 - 9.1e-07 28.6 152.7 0.057 13.0 4.9 9.0 3 2 6 9 9 8 5 IncA protein CCDC144C PF14915.1 KPI38575.1 - 1.3e-05 24.2 16.2 1.3e-05 24.2 11.2 6.3 3 2 3 6 6 4 1 CCDC144C protein coiled-coil region Myosin_tail_1 PF01576.14 KPI38575.1 - 3.3e-05 21.8 72.3 3.3e-05 21.8 50.1 5.3 3 2 2 5 5 5 3 Myosin tail Reo_sigmaC PF04582.7 KPI38575.1 - 7.3e-05 22.1 66.0 0.0013 18.0 5.1 6.9 3 2 4 7 7 7 4 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 KPI38575.1 - 0.00023 21.0 12.7 0.00023 21.0 8.8 9.0 3 2 4 8 8 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.6 KPI38575.1 - 0.0007 19.0 3.3 0.0007 19.0 2.3 11.4 4 3 7 11 11 11 4 Phage minor structural protein GP20 GAS PF13851.1 KPI38575.1 - 0.0024 17.1 14.8 0.0024 17.1 10.2 9.1 3 2 6 9 9 9 4 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.17 KPI38575.1 - 0.0035 17.3 12.5 0.0035 17.3 8.6 11.5 4 3 7 12 12 12 2 Seryl-tRNA synthetase N-terminal domain AAA_13 PF13166.1 KPI38575.1 - 0.13 10.7 111.2 0.057 11.8 17.6 5.4 2 2 2 5 5 5 0 AAA domain MscS_porin PF12795.2 KPI38575.1 - 2.9 7.1 148.8 0.26 10.5 14.4 7.8 3 2 2 6 6 6 0 Mechanosensitive ion channel porin domain FlaC_arch PF05377.6 KPI38575.1 - 5.4 6.9 52.6 1.9 8.4 0.4 11.8 11 3 1 12 12 12 0 Flagella accessory protein C (FlaC) DOT1 PF08123.8 KPI38576.1 - 2.2e-71 239.3 0.0 3.1e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 KPI38576.1 - 0.0031 17.5 0.0 0.0068 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI38576.1 - 0.032 14.7 0.1 0.076 13.6 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF3415 PF11895.3 KPI38576.1 - 0.093 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3415) PGBA_C PF15437.1 KPI38576.1 - 0.28 11.3 4.0 0.64 10.1 2.6 1.7 1 1 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal DUF2360 PF10152.4 KPI38577.1 - 7.3 6.8 9.5 0.1 12.8 0.6 2.4 2 2 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) LSM PF01423.17 KPI38578.1 - 1.9e-13 49.7 0.0 3e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 LSM domain Snf7 PF03357.16 KPI38579.1 - 1.3e-23 83.2 18.4 1.3e-23 83.2 12.7 2.1 1 1 1 2 2 2 1 Snf7 Fib_alpha PF08702.5 KPI38579.1 - 4.2 7.4 24.4 1.4 9.0 0.4 3.8 1 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Hemerythrin PF01814.18 KPI38580.1 - 1.5e-11 44.5 2.7 2e-11 44.2 1.9 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Fungal_trans PF04082.13 KPI38581.1 - 5.8e-09 35.1 1.0 1.1e-08 34.2 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI38581.1 - 8.4e-05 22.3 9.1 0.0002 21.2 6.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFCD_C PF12612.3 KPI38582.1 - 9.1e-20 70.9 0.2 4.1e-19 68.7 0.1 2.3 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 KPI38582.1 - 0.015 15.3 13.8 0.38 10.9 0.0 6.6 8 0 0 8 8 8 0 HEAT repeat Vac14_Fab1_bd PF12755.2 KPI38582.1 - 0.075 13.4 0.1 2.2 8.7 0.0 3.4 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Rgp1 PF08737.5 KPI38583.1 - 0.03 13.4 0.1 0.031 13.3 0.1 1.1 1 0 0 1 1 1 0 Rgp1 DUF1104 PF06518.6 KPI38583.1 - 0.036 14.2 0.1 0.083 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) Gp-FAR-1 PF05823.7 KPI38583.1 - 0.069 13.1 0.2 0.12 12.2 0.1 1.6 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) WD40_alt PF14077.1 KPI38583.1 - 0.096 12.3 0.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif Pkinase PF00069.20 KPI38584.1 - 2.6e-63 213.6 0.0 3.7e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI38584.1 - 2.8e-36 124.9 0.0 4e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KPI38584.1 - 3.4e-12 46.6 0.6 1.2e-11 44.9 0.4 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain PAT1 PF09770.4 KPI38584.1 - 0.0021 16.4 42.3 0.0028 16.0 29.3 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Kinase-like PF14531.1 KPI38584.1 - 0.0073 15.3 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SnoaL_2 PF12680.2 KPI38585.1 - 4.7e-09 36.5 0.0 7.7e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain RNA_pol PF00940.14 KPI38587.1 - 6.7e-164 545.1 0.0 8.2e-164 544.8 0.0 1.1 1 0 0 1 1 1 1 DNA-dependent RNA polymerase PAXNEB PF05625.6 KPI38588.1 - 1.9e-102 342.8 0.0 2.1e-102 342.7 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein Zn_clus PF00172.13 KPI38589.1 - 4.1e-06 26.6 14.9 5.6e-06 26.1 10.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Apq12 PF12716.2 KPI38590.1 - 4.6e-10 39.0 8.0 4.6e-10 39.0 5.5 1.8 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis Amastin PF07344.6 KPI38590.1 - 0.016 14.7 0.1 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Amastin surface glycoprotein Pyr_redox_3 PF13738.1 KPI38591.1 - 4.7e-25 88.8 2.1 6.2e-22 78.6 1.5 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI38591.1 - 2.9e-16 58.7 2.5 1.9e-12 46.1 0.0 3.0 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KPI38591.1 - 6.3e-11 42.5 0.0 3.9e-07 30.1 0.0 3.0 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI38591.1 - 3.8e-07 30.0 0.1 1.4e-06 28.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI38591.1 - 6.4e-07 28.5 1.9 5.9e-05 22.1 0.5 3.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 KPI38591.1 - 3.1e-06 26.3 0.2 0.00011 21.2 0.1 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 KPI38591.1 - 0.00024 20.0 0.5 0.00045 19.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KPI38591.1 - 0.00031 20.5 4.1 0.1 12.3 0.1 4.2 3 2 1 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.12 KPI38591.1 - 0.00067 18.8 0.0 0.0066 15.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 KPI38591.1 - 0.00075 19.7 0.4 1.4 9.2 0.0 3.0 2 1 0 2 2 2 2 Putative NAD(P)-binding Shikimate_DH PF01488.15 KPI38591.1 - 0.0016 18.5 0.0 0.26 11.3 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 KPI38591.1 - 0.014 14.3 0.1 0.029 13.2 0.1 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 KPI38591.1 - 0.014 15.7 0.0 6.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KPI38591.1 - 0.016 14.2 0.3 0.29 10.1 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.14 KPI38591.1 - 0.035 13.2 0.0 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 KPI38591.1 - 0.036 12.5 0.3 0.38 9.1 0.3 2.2 2 0 0 2 2 2 0 HI0933-like protein DUF4139 PF13598.1 KPI38592.1 - 0.15 11.3 4.0 0.17 11.1 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) Tis11B_N PF04553.7 KPI38592.1 - 0.43 10.7 2.6 0.63 10.2 1.4 1.7 1 1 0 1 1 1 0 Tis11B like protein, N terminus Macoilin PF09726.4 KPI38592.1 - 0.7 8.1 3.2 0.79 7.9 2.2 1.0 1 0 0 1 1 1 0 Transmembrane protein Herpes_capsid PF06112.6 KPI38592.1 - 1.8 8.5 8.1 2.2 8.3 5.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Cyclin PF08613.6 KPI38593.1 - 1.2e-13 51.7 0.0 1.9e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KPI38593.1 - 0.058 12.9 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Kelch_3 PF13415.1 KPI38593.1 - 4 7.7 7.4 3.8 7.8 0.4 3.5 4 0 0 4 4 4 0 Galactose oxidase, central domain Pyr_redox_2 PF07992.9 KPI38594.1 - 1.2e-27 97.0 0.0 2e-27 96.3 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI38594.1 - 2.8e-23 82.1 1.1 1.1e-19 70.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KPI38594.1 - 1.1e-20 73.6 0.0 2.6e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GIDA PF01134.17 KPI38594.1 - 5.7e-05 22.1 1.0 0.0038 16.1 0.8 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KPI38594.1 - 9.5e-05 22.3 1.4 0.082 12.9 0.3 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KPI38594.1 - 0.00013 21.1 0.5 0.31 10.0 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain 3HCDH_N PF02737.13 KPI38594.1 - 0.00028 20.5 0.4 0.17 11.5 0.0 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 KPI38594.1 - 0.0012 18.9 2.0 0.2 11.7 0.6 3.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI38594.1 - 0.0048 15.7 1.3 0.021 13.6 0.7 2.1 2 0 0 2 2 2 1 FAD binding domain XdhC_C PF13478.1 KPI38594.1 - 0.0086 16.3 0.0 0.15 12.3 0.0 2.2 2 0 0 2 2 2 1 XdhC Rossmann domain Thi4 PF01946.12 KPI38594.1 - 0.014 14.4 0.1 1.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.2 KPI38594.1 - 0.015 14.4 5.1 0.029 13.4 1.0 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KPI38594.1 - 0.018 15.2 0.2 0.35 11.1 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 KPI38594.1 - 0.029 13.5 0.1 0.1 11.7 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 KPI38594.1 - 0.069 13.1 0.2 3.7 7.5 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain CPSase_L_chain PF00289.17 KPI38594.1 - 0.073 13.1 0.0 0.82 9.7 0.0 2.3 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain HI0933_like PF03486.9 KPI38594.1 - 0.11 10.9 3.0 4.4 5.6 0.1 2.5 2 1 1 3 3 3 0 HI0933-like protein LRR_9 PF14580.1 KPI38595.1 - 4.3e-51 172.9 0.3 6.3e-51 172.4 0.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 KPI38595.1 - 1.7e-09 37.2 5.3 3.4e-08 33.1 1.7 2.9 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.2 KPI38595.1 - 1.1e-07 31.3 14.3 1.3e-05 24.7 1.6 4.2 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KPI38595.1 - 0.062 13.4 7.1 2.2 8.6 0.0 3.9 4 1 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.28 KPI38595.1 - 2 8.7 13.6 10 6.6 0.1 5.4 6 0 0 6 6 6 0 Leucine Rich Repeat Aminotran_1_2 PF00155.16 KPI38596.1 - 5.7e-57 193.3 0.0 1e-56 192.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KPI38596.1 - 0.00043 19.1 0.0 0.001 17.8 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KPI38596.1 - 0.0026 16.9 0.0 0.0041 16.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Pkinase PF00069.20 KPI38598.1 - 9.5e-41 139.6 0.0 2.3e-40 138.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI38598.1 - 2.2e-25 89.2 0.0 4.8e-21 75.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RE_AlwI PF09491.5 KPI38598.1 - 0.0073 14.8 0.0 0.011 14.2 0.0 1.1 1 0 0 1 1 1 1 AlwI restriction endonuclease adh_short PF00106.20 KPI38600.1 - 4.1e-36 124.4 0.0 5.5e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI38600.1 - 1.1e-15 57.8 0.0 1.6e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI38600.1 - 3.8e-15 56.3 0.0 5.2e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KPI38600.1 - 0.00019 20.9 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KPI38600.1 - 0.0016 17.4 0.1 0.0045 15.9 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KPI38600.1 - 0.0021 17.7 0.2 0.005 16.6 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Cyanate_lyase PF02560.9 KPI38601.1 - 3.7e-29 100.0 0.1 5.5e-29 99.5 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.17 KPI38601.1 - 0.0045 16.7 0.0 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix DUF3698 PF12479.3 KPI38601.1 - 0.079 13.0 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3698) zf-RING_2 PF13639.1 KPI38602.1 - 0.29 11.0 5.3 0.55 10.1 3.7 1.5 1 0 0 1 1 1 0 Ring finger domain TPR_1 PF00515.23 KPI38603.1 - 2.9e-53 175.4 30.5 3.8e-08 32.5 0.0 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 KPI38603.1 - 6.9e-46 150.5 24.1 7e-06 25.5 0.0 10.3 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 KPI38603.1 - 1.2e-42 143.3 22.8 7.5e-13 47.9 1.8 6.4 3 2 3 7 7 7 7 TPR repeat TPR_8 PF13181.1 KPI38603.1 - 1.6e-36 121.2 19.9 1.3e-05 24.6 0.0 10.3 8 1 2 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 KPI38603.1 - 1.5e-32 111.5 16.1 1.3e-07 32.0 0.3 6.6 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 KPI38603.1 - 1.2e-30 105.2 24.0 9.6e-07 28.6 0.1 7.7 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.1 KPI38603.1 - 1.6e-23 81.0 12.2 0.00021 21.6 0.0 8.7 4 3 6 10 10 10 6 Tetratricopeptide repeat TPR_17 PF13431.1 KPI38603.1 - 4.7e-23 79.4 23.0 0.00033 20.6 0.1 10.8 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.1 KPI38603.1 - 1.1e-21 76.9 17.7 1.6e-06 28.3 0.1 7.0 4 2 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 KPI38603.1 - 4.6e-20 69.7 12.7 0.0059 16.3 0.0 9.3 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.1 KPI38603.1 - 2.5e-19 68.3 18.1 0.0086 16.4 0.0 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 KPI38603.1 - 2.4e-12 46.5 13.5 0.0012 18.6 0.1 6.9 1 1 5 7 7 7 4 Tetratricopeptide repeat Apc3 PF12895.2 KPI38603.1 - 2.1e-10 40.6 15.7 5e-07 29.7 1.2 3.9 4 1 1 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KPI38603.1 - 1.9e-07 30.4 14.3 0.00014 21.0 1.3 4.7 1 1 3 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KPI38603.1 - 0.00054 19.7 0.3 0.76 9.7 0.0 4.1 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.4 KPI38603.1 - 0.0025 17.7 17.0 0.15 12.0 2.0 4.0 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 KPI38603.1 - 0.0051 16.8 0.7 1.9 8.6 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat ChAPs PF09295.5 KPI38603.1 - 0.33 9.6 3.6 7.7 5.1 0.1 2.8 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 KPI38603.1 - 1.1 9.2 20.2 17 5.5 0.1 7.7 10 0 0 10 10 9 0 Tetratricopeptide repeat BLOC1_2 PF10046.4 KPI38603.1 - 1.5 8.9 4.2 0.88 9.7 0.8 2.2 3 0 0 3 3 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Abhydrolase_3 PF07859.8 KPI38604.1 - 4e-35 121.3 0.0 5.8e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI38604.1 - 0.00014 21.5 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI38604.1 - 0.00027 20.2 0.0 0.00051 19.3 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KPI38604.1 - 0.00035 20.5 0.6 0.00067 19.5 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KPI38604.1 - 0.00038 19.9 0.0 0.0021 17.5 0.0 1.9 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase COesterase PF00135.23 KPI38604.1 - 0.0051 15.5 0.0 0.0096 14.6 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.7 KPI38604.1 - 0.0063 15.0 0.0 0.0092 14.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF2974 PF11187.3 KPI38604.1 - 0.0097 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 KPI38604.1 - 0.065 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 KPI38604.1 - 0.11 12.6 0.1 0.25 11.5 0.0 1.5 2 0 0 2 2 2 0 Thioesterase domain Chlorophyllase2 PF12740.2 KPI38604.1 - 0.18 10.6 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme HR1 PF02185.11 KPI38607.1 - 5.7e-34 115.6 11.6 1.8e-19 69.2 2.3 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 KPI38607.1 - 3.3e-12 45.9 15.4 2.1e-10 40.1 7.0 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.25 KPI38607.1 - 0.029 14.1 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 C2 domain Uds1 PF15456.1 KPI38607.1 - 4.6 7.2 7.3 0.79 9.7 0.6 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Cmc1 PF08583.5 KPI38609.1 - 3.6e-16 58.6 0.4 4.4e-16 58.3 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1018 PF06252.7 KPI38609.1 - 0.011 16.1 0.0 0.014 15.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Abhydrolase_6 PF12697.2 KPI38610.1 - 8.2e-08 32.3 0.0 1.4e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI38610.1 - 0.029 14.1 0.0 0.064 13.0 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI38610.1 - 0.093 11.9 0.3 6.5 5.9 0.1 2.5 2 1 0 2 2 2 0 Prolyl oligopeptidase family Glyoxalase_3 PF13468.1 KPI38611.1 - 2.5e-19 69.8 0.0 6.2e-19 68.5 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase-like domain Nse4_C PF08743.5 KPI38612.1 - 6.5e-25 86.9 0.0 3.2e-24 84.7 0.0 2.2 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KPI38612.1 - 3e-17 62.2 0.4 9.4e-17 60.6 0.1 2.1 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE Methyltransf_11 PF08241.7 KPI38613.1 - 7.3e-05 23.1 0.0 0.00018 21.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI38613.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cg6151-P PF10233.4 KPI38614.1 - 5.9e-40 135.7 14.6 7.1e-40 135.5 10.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF2207 PF09972.4 KPI38614.1 - 0.25 9.9 8.1 0.28 9.6 5.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3040 PF11239.3 KPI38614.1 - 0.6 10.1 8.6 5.4 7.1 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) PRA1 PF03208.14 KPI38614.1 - 1.5 8.1 11.0 2 7.7 7.6 1.2 1 0 0 1 1 1 0 PRA1 family protein zf-DHHC PF01529.15 KPI38614.1 - 2.4 7.5 8.5 3.1 7.1 5.9 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DAD PF02109.11 KPI38615.1 - 4.8e-37 126.4 1.8 1.7e-35 121.5 1.2 2.1 1 1 0 1 1 1 1 DAD family NDUF_B12 PF08122.7 KPI38615.1 - 0.085 12.6 0.2 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Pex14_N PF04695.8 KPI38615.1 - 5.2 7.1 8.2 11 6.0 4.9 1.9 1 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PRCC PF10253.4 KPI38615.1 - 5.6 7.6 8.6 5.9 7.5 5.9 1.3 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Atg14 PF10186.4 KPI38616.1 - 0.093 11.6 3.5 0.15 11.0 2.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HisKA_3 PF07730.8 KPI38616.1 - 0.13 12.5 4.2 0.14 12.5 0.7 2.4 1 1 1 2 2 2 0 Histidine kinase APG6 PF04111.7 KPI38616.1 - 0.3 10.1 3.1 0.41 9.6 2.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 S-AdoMet_synt_C PF02773.11 KPI38618.1 - 6.4e-75 249.4 0.1 1e-74 248.8 0.1 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KPI38618.1 - 1.8e-34 118.2 1.6 4.2e-17 62.1 0.0 2.8 2 1 1 3 3 3 2 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KPI38618.1 - 6.5e-31 106.5 0.7 1.1e-30 105.7 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain SRP9-21 PF05486.7 KPI38619.1 - 6.2e-19 67.5 5.9 3e-18 65.3 4.1 1.9 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Sin_N PF04801.8 KPI38619.1 - 0.063 12.1 0.9 0.099 11.4 0.6 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Dicty_REP PF05086.7 KPI38619.1 - 0.069 10.9 0.9 0.079 10.7 0.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AAA PF00004.24 KPI38620.1 - 1.8e-14 54.0 0.0 4e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KPI38620.1 - 4e-09 36.7 0.0 1.6e-08 34.7 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KPI38620.1 - 7.2e-08 32.6 0.0 2.4e-07 30.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain BAH PF01426.13 KPI38620.1 - 3.3e-05 23.6 0.0 7.2e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.1 KPI38620.1 - 0.00052 19.7 0.4 0.0035 17.0 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KPI38620.1 - 0.0057 17.4 0.0 0.029 15.1 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 KPI38620.1 - 0.0064 16.7 0.0 0.031 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KPI38620.1 - 0.035 13.6 0.0 0.08 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KPI38620.1 - 0.035 14.0 0.0 0.088 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KPI38620.1 - 0.036 13.0 0.0 0.081 11.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 KPI38620.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 KPI38620.1 - 0.06 13.2 0.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 KPI38620.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_32 PF13654.1 KPI38620.1 - 0.13 10.9 0.2 0.31 9.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain PAPS_reduct PF01507.14 KPI38621.1 - 3.9e-21 75.6 0.0 1.2e-20 74.1 0.0 1.8 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF3449 PF11931.3 KPI38622.1 - 3.5e-68 229.0 0.0 9.3e-68 227.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) zf-met PF12874.2 KPI38622.1 - 6.7e-10 38.8 1.0 1.8e-07 31.1 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.3 KPI38622.1 - 1.1e-07 31.2 0.6 2.3e-07 30.2 0.4 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 KPI38622.1 - 1.1e-07 31.7 3.7 9.4e-07 28.8 0.0 2.8 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KPI38622.1 - 0.00052 20.0 0.3 0.041 13.9 0.0 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF951 PF06107.6 KPI38622.1 - 0.037 13.5 0.5 0.086 12.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) zf-U1 PF06220.7 KPI38622.1 - 0.12 11.9 0.1 0.36 10.4 0.0 1.8 1 0 0 1 1 1 0 U1 zinc finger IncA PF04156.9 KPI38622.1 - 0.28 10.7 2.9 0.64 9.5 2.0 1.6 1 0 0 1 1 1 0 IncA protein Kei1 PF08552.6 KPI38623.1 - 0.25 10.9 2.5 0.64 9.6 1.1 2.1 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 TFIIA PF03153.8 KPI38623.1 - 1.2 9.0 9.8 1.4 8.7 6.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.4 KPI38623.1 - 3.8 6.0 15.0 4.8 5.7 10.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ATG16 PF08614.6 KPI38624.1 - 2.1e-33 115.7 17.4 2.6e-33 115.4 12.0 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4201 PF13870.1 KPI38624.1 - 0.0076 15.7 17.3 0.012 15.0 12.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Reo_sigmaC PF04582.7 KPI38624.1 - 0.064 12.4 1.7 0.077 12.1 1.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Flagellar_rod PF05149.7 KPI38624.1 - 0.16 11.0 15.5 0.21 10.7 10.7 1.2 1 0 0 1 1 1 0 Paraflagellar rod protein DUF3166 PF11365.3 KPI38624.1 - 0.22 12.0 12.9 1.3 9.5 2.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) GAS PF13851.1 KPI38624.1 - 0.23 10.6 20.4 8.9 5.4 6.7 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 KPI38624.1 - 0.26 8.5 19.5 0.32 8.2 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 KPI38624.1 - 0.82 8.5 18.2 1.1 8.0 12.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 UPF0242 PF06785.6 KPI38624.1 - 1.1 7.8 9.1 1.4 7.4 6.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) AAA_13 PF13166.1 KPI38624.1 - 1.2 7.5 11.4 1.6 7.1 7.9 1.1 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.7 KPI38624.1 - 3.3 7.4 15.3 0.32 10.7 2.8 2.2 1 1 1 2 2 2 0 Laminin Domain II PEP-utilisers_N PF05524.8 KPI38624.1 - 6 6.6 9.0 19 5.0 6.3 2.0 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Bap31 PF05529.7 KPI38624.1 - 7.7 5.9 11.2 0.16 11.4 0.1 2.2 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like His_Phos_1 PF00300.17 KPI38626.1 - 2.8e-30 105.4 0.0 3.4e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) G-alpha PF00503.15 KPI38627.1 - 1.4e-115 386.1 0.2 1.6e-115 385.8 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KPI38627.1 - 2.4e-14 52.9 0.3 4e-09 35.9 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KPI38627.1 - 0.0037 16.4 4.3 0.28 10.2 0.1 2.8 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KPI38627.1 - 0.0092 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 KPI38627.1 - 0.021 15.3 0.0 0.61 10.6 0.0 2.7 2 1 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 KPI38627.1 - 0.025 14.0 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 KPI38627.1 - 0.073 12.9 0.5 3.6 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KPI38627.1 - 0.079 12.9 0.0 8.2 6.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase MFS_1 PF07690.11 KPI38628.1 - 5.5e-33 114.1 41.3 9.1e-33 113.4 13.8 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI38628.1 - 1.8e-10 39.9 6.1 1.8e-10 39.9 4.2 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KPI38628.1 - 0.0069 14.6 4.6 0.012 13.8 3.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 KPI38629.1 - 1.4e-11 43.7 0.4 3.2e-11 42.5 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KPI38629.1 - 0.013 15.7 4.9 0.013 15.7 3.4 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 KPI38629.1 - 0.025 14.8 1.1 0.089 13.1 0.7 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI38629.1 - 0.029 14.7 1.7 0.089 13.1 1.2 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type PilP PF04351.8 KPI38630.1 - 0.023 14.5 0.2 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Pilus assembly protein, PilP Laminin_II PF06009.7 KPI38630.1 - 0.17 11.6 0.7 0.42 10.3 0.1 1.9 2 0 0 2 2 2 0 Laminin Domain II GTP_EFTU PF00009.22 KPI38631.1 - 8.4e-53 178.5 0.1 1.8e-52 177.5 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KPI38631.1 - 1.2e-14 53.9 0.0 3.2e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KPI38631.1 - 3.6e-08 33.1 0.0 7.5e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KPI38631.1 - 1.4e-05 25.1 0.0 3.6e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 KPI38631.1 - 0.0062 16.0 0.0 0.072 12.6 0.0 2.6 3 0 0 3 3 3 1 Elongation factor G, domain IV TPPK_C PF12555.3 KPI38631.1 - 1.1 9.0 3.3 1.4 8.7 0.6 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal EamA PF00892.15 KPI38632.1 - 4.7e-08 33.1 4.2 4.7e-08 33.1 2.9 3.4 3 1 1 4 4 4 1 EamA-like transporter family EmrE PF13536.1 KPI38632.1 - 4.9e-07 29.9 4.3 4.9e-07 29.9 3.0 3.3 3 1 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 KPI38632.1 - 6.5e-06 25.8 20.0 3.7e-05 23.4 1.3 2.8 3 0 0 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 KPI38632.1 - 3.1e-05 23.0 3.6 3.1e-05 23.0 2.5 1.5 2 0 0 2 2 2 1 UAA transporter family DUF914 PF06027.7 KPI38632.1 - 0.0011 17.8 4.6 0.017 13.9 0.7 3.0 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) RasGEF PF00617.14 KPI38635.1 - 1.2e-64 217.4 0.1 2.4e-64 216.5 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KPI38635.1 - 1.7e-27 95.5 0.1 4.9e-27 94.0 0.1 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KPI38635.1 - 2.4e-15 55.6 0.2 5.2e-15 54.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KPI38635.1 - 1.2e-13 50.3 0.2 2.7e-13 49.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KPI38635.1 - 1.8e-10 40.1 0.0 4.6e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 KPI38635.1 - 3.5e-05 23.5 0.0 0.00012 21.8 0.0 1.9 1 0 0 1 1 1 1 WW domain Ras PF00071.17 KPI38636.1 - 5.9e-57 191.5 0.1 6.9e-57 191.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KPI38636.1 - 1.1e-19 71.0 0.0 1.7e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KPI38636.1 - 1.9e-13 50.0 0.0 2.2e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KPI38636.1 - 3.3e-08 32.9 0.0 4e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KPI38636.1 - 1.2e-07 31.6 0.0 1.6e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KPI38636.1 - 1.6e-06 27.6 0.0 3.2e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KPI38636.1 - 0.00077 18.6 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KPI38636.1 - 0.00087 19.4 0.0 0.0014 18.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 KPI38636.1 - 0.0018 17.5 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.14 KPI38636.1 - 0.0018 17.7 0.0 0.0083 15.5 0.0 1.9 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KPI38636.1 - 0.0024 17.8 0.0 0.02 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 KPI38636.1 - 0.003 17.1 0.3 0.12 11.9 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 KPI38636.1 - 0.0037 16.8 0.3 0.0075 15.8 0.1 1.6 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KPI38636.1 - 0.0059 16.3 0.1 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_10 PF12846.2 KPI38636.1 - 0.0088 15.5 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain Septin PF00735.13 KPI38636.1 - 0.009 15.0 0.1 0.018 14.0 0.0 1.5 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.4 KPI38636.1 - 0.022 14.2 0.1 0.077 12.4 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 KPI38636.1 - 0.025 14.2 0.1 0.053 13.2 0.1 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KPI38636.1 - 0.057 13.1 0.1 0.097 12.3 0.0 1.4 2 0 0 2 2 2 0 NTPase NACHT PF05729.7 KPI38636.1 - 0.082 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 KPI38636.1 - 0.095 12.4 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PNPOx_C PF10590.4 KPI38638.1 - 1.6e-23 81.8 1.9 4.8e-23 80.3 1.3 1.8 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 KPI38638.1 - 6e-18 64.6 0.0 9.5e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 KPI38638.1 - 0.004 17.4 0.1 0.008 16.4 0.1 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2262 PF10020.4 KPI38639.1 - 0.0065 16.6 0.4 0.013 15.7 0.3 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2262) RPOL_N PF14700.1 KPI38640.1 - 1.1e-66 225.3 3.8 1.5e-66 224.8 2.6 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal VPS11_C PF12451.3 KPI38641.1 - 6.3e-19 67.5 0.1 2.1e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.15 KPI38641.1 - 1.3e-17 63.7 0.8 1.3e-17 63.7 0.6 2.6 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 KPI38641.1 - 4.7e-05 23.1 5.4 0.00011 21.9 3.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KPI38641.1 - 0.00024 20.7 6.2 0.00047 19.8 4.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KPI38641.1 - 0.00027 20.8 4.5 0.00053 19.9 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI38641.1 - 0.0048 16.5 6.4 0.0092 15.6 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.1 KPI38641.1 - 0.0079 16.7 0.0 2.4 9.0 0.0 3.7 3 0 0 3 3 2 1 Tetratricopeptide repeat zf-Apc11 PF12861.2 KPI38641.1 - 0.011 15.5 0.8 0.024 14.4 0.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KPI38641.1 - 0.011 15.8 2.8 0.022 14.8 1.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger TPR_11 PF13414.1 KPI38641.1 - 0.022 14.3 0.4 0.08 12.6 0.0 2.2 2 0 0 2 2 2 0 TPR repeat zf-HC5HC2H PF13771.1 KPI38641.1 - 0.028 14.5 1.6 0.058 13.5 1.1 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain TPR_2 PF07719.12 KPI38641.1 - 0.067 13.1 1.1 0.43 10.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.1 KPI38641.1 - 0.13 12.1 4.6 0.28 11.1 3.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TPR_8 PF13181.1 KPI38641.1 - 0.17 11.7 3.9 0.32 10.8 0.1 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.1 KPI38641.1 - 0.39 10.4 3.8 0.77 9.4 2.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 KPI38641.1 - 2.3 7.9 6.6 3.4 7.4 3.4 2.1 2 0 0 2 2 2 0 PHD-finger TPR_12 PF13424.1 KPI38641.1 - 6.5 6.7 10.0 1 9.3 0.2 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat WD40 PF00400.27 KPI38642.1 - 3.1e-26 90.2 2.6 4.2e-08 32.7 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 KPI38642.1 - 1.1e-05 23.8 2.7 0.00045 18.4 0.3 2.9 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Cyclin_N PF00134.18 KPI38642.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Arrestin_C PF02752.17 KPI38643.1 - 3.3e-23 82.2 0.0 1.2e-22 80.5 0.0 2.0 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KPI38643.1 - 3.2e-10 40.0 0.0 1.3e-05 25.0 0.0 3.3 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain FMN_dh PF01070.13 KPI38645.1 - 3.1e-107 358.5 0.1 5.7e-68 229.3 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 KPI38645.1 - 2.8e-08 33.0 0.4 7.4e-08 31.6 0.2 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KPI38645.1 - 9.9e-08 31.4 0.1 1.5e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 KPI38645.1 - 9.3e-07 28.0 0.1 1.5e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KPI38645.1 - 2.6e-05 23.6 0.1 0.00033 20.0 0.0 2.1 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 KPI38645.1 - 0.0025 16.9 0.8 0.041 12.9 0.0 2.2 1 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 KPI38645.1 - 0.021 13.8 0.0 0.06 12.2 0.0 1.7 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase PcrB PF01884.12 KPI38645.1 - 0.051 12.8 0.7 2.5 7.3 0.0 2.3 1 1 1 2 2 2 0 PcrB family Transketolase_N PF00456.16 KPI38646.1 - 2.8e-146 486.5 0.3 3.7e-146 486.2 0.2 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KPI38646.1 - 8.1e-45 152.4 0.0 1.3e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KPI38646.1 - 3.3e-14 52.8 0.0 6.6e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KPI38646.1 - 2.8e-05 23.1 0.0 5.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 KPI38646.1 - 0.0006 18.6 0.1 0.00098 17.9 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component CHAD PF05235.9 KPI38646.1 - 0.095 12.2 0.6 0.16 11.5 0.4 1.3 1 0 0 1 1 1 0 CHAD domain PRMT5 PF05185.11 KPI38647.1 - 5.6e-160 533.1 0.0 7.2e-159 529.4 0.0 2.1 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase HEAT PF02985.17 KPI38648.1 - 3.4e-26 88.9 8.1 2.4e-05 24.0 0.0 9.4 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 KPI38648.1 - 2.4e-25 88.2 2.5 1.3e-14 54.1 0.0 8.5 6 1 3 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.1 KPI38648.1 - 1.5e-18 66.8 0.0 7.2e-07 29.3 0.0 7.0 4 3 3 7 7 7 4 HEAT repeats Vac14_Fab1_bd PF12755.2 KPI38648.1 - 9.1e-10 38.8 0.1 0.00078 19.7 0.0 5.7 3 3 4 7 7 7 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 KPI38648.1 - 5.4e-09 35.8 5.7 1.6e-06 27.8 0.1 5.9 6 1 1 7 7 5 1 Importin-beta N-terminal domain Cnd1 PF12717.2 KPI38648.1 - 3.9e-08 33.3 0.9 0.011 15.5 0.0 5.4 4 2 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 KPI38648.1 - 6.2e-06 25.1 1.4 0.04 12.6 0.0 4.1 3 2 1 4 4 4 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 KPI38648.1 - 0.00027 20.3 0.1 4.1 6.6 0.0 4.6 4 0 0 4 4 4 1 CLASP N terminal RIX1 PF08167.7 KPI38648.1 - 0.00039 20.1 0.8 12 5.5 0.0 4.2 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.11 KPI38648.1 - 0.0017 18.6 2.9 1.2 9.7 0.0 5.3 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat DUF3437 PF11919.3 KPI38648.1 - 0.0077 15.9 0.2 0.14 11.8 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) Arm PF00514.18 KPI38648.1 - 0.044 13.6 0.1 0.44 10.4 0.0 2.8 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat DUF2454 PF10521.4 KPI38648.1 - 0.048 12.6 0.5 0.55 9.1 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2454) Git3 PF11710.3 KPI38649.1 - 6.9e-21 74.7 16.6 1.6e-20 73.5 11.5 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KPI38649.1 - 2.1e-08 33.6 16.7 3.1e-08 33.0 11.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 KPI38649.1 - 2.5e-06 27.1 1.0 2.5e-06 27.1 0.7 2.2 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 KPI38649.1 - 0.0033 16.3 14.4 0.0044 15.9 10.0 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Usp PF00582.21 KPI38651.1 - 4.9e-17 62.4 0.2 3.6e-15 56.3 0.1 2.7 1 1 0 1 1 1 1 Universal stress protein family DEAD PF00270.24 KPI38652.1 - 3.8e-41 140.3 0.2 6.9e-41 139.5 0.1 1.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI38652.1 - 3.4e-29 100.5 0.1 6.7e-29 99.5 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KPI38652.1 - 0.00053 19.6 0.1 0.0012 18.6 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 KPI38652.1 - 0.0032 17.3 0.1 0.0061 16.4 0.1 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KPI38652.1 - 0.0052 16.3 0.3 0.011 15.3 0.2 1.5 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 KPI38652.1 - 0.0091 15.7 0.0 0.025 14.3 0.0 1.8 1 0 0 1 1 1 1 Flavivirus DEAD domain Helicase_RecD PF05127.9 KPI38652.1 - 0.033 13.8 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Helicase SNF2_N PF00176.18 KPI38652.1 - 0.033 12.9 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_11 PF13086.1 KPI38652.1 - 0.057 12.9 0.4 0.11 12.0 0.2 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KPI38652.1 - 0.075 13.1 0.6 0.27 11.3 0.4 1.9 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.11 KPI38653.1 - 7e-44 149.9 42.6 1.1e-43 149.3 29.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI38653.1 - 9.1e-18 64.0 11.1 9.1e-18 64.0 7.7 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 KPI38653.1 - 3.7e-08 32.0 23.3 5.1e-08 31.5 16.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3425 PF11905.3 KPI38654.1 - 1.2e-17 64.0 0.1 3.1e-17 62.7 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) FAD_binding_3 PF01494.14 KPI38655.1 - 2.3e-65 220.9 0.0 9.1e-51 172.9 0.0 2.3 1 1 1 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.7 KPI38655.1 - 3.1e-57 192.8 0.0 5.1e-57 192.1 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 KPI38655.1 - 0.0011 17.5 0.0 0.0018 16.8 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KPI38655.1 - 0.0011 18.8 0.0 0.003 17.4 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI38655.1 - 0.0045 15.9 0.0 0.01 14.7 0.0 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KPI38655.1 - 0.0051 15.9 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KPI38655.1 - 0.014 14.3 0.1 0.041 12.7 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI38655.1 - 0.024 14.6 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KPI38655.1 - 0.029 14.7 0.0 0.11 12.9 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KPI38655.1 - 0.035 13.6 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KPI38655.1 - 0.043 13.8 0.2 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DcpS_C PF11969.3 KPI38656.1 - 6.6e-15 55.3 4.5 2.7e-14 53.4 3.1 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KPI38656.1 - 4.4e-12 46.3 0.2 1.1e-11 45.0 0.1 1.7 1 1 0 1 1 1 1 HIT domain Rho_GDI PF02115.12 KPI38657.1 - 2.6e-58 196.7 0.0 3.1e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor NMO PF03060.10 KPI38658.1 - 8.8e-65 219.0 3.6 1.1e-64 218.6 2.5 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KPI38658.1 - 3.6e-09 35.9 1.2 7.2e-09 34.9 0.8 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KPI38658.1 - 9.6e-06 24.6 3.5 9.6e-06 24.6 2.4 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KPI38658.1 - 0.0038 16.1 0.8 0.0074 15.2 0.6 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 KPI38658.1 - 0.049 12.5 0.7 0.11 11.3 0.4 1.7 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase PTPLA PF04387.9 KPI38659.1 - 6.4e-52 175.2 3.3 1.2e-51 174.3 2.3 1.5 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Fungal_trans PF04082.13 KPI38660.1 - 0.0028 16.5 0.0 0.0062 15.4 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Rav1p_C PF12234.3 KPI38661.1 - 0.15 10.1 0.0 0.21 9.7 0.0 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal TruB_N PF01509.13 KPI38662.1 - 2.3e-41 141.4 0.0 1.6e-40 138.7 0.0 2.1 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) DUF775 PF05603.7 KPI38663.1 - 5.2e-54 182.8 0.0 6.3e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Asp PF00026.18 KPI38664.1 - 2.4e-16 59.8 0.0 1.4e-15 57.4 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease HemY_N PF07219.8 KPI38664.1 - 0.054 13.0 0.3 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 HemY protein N-terminus VSP PF03302.8 KPI38664.1 - 0.064 11.8 0.5 0.12 10.9 0.3 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.5 KPI38664.1 - 0.28 10.5 2.1 0.58 9.5 1.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PRP38 PF03371.10 KPI38665.1 - 1.2e-62 210.5 0.0 1.5e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 PRP38 family F-box PF00646.28 KPI38666.1 - 0.013 15.1 0.2 0.069 12.8 0.0 2.4 2 1 0 2 2 2 0 F-box domain F-box-like_2 PF13013.1 KPI38666.1 - 0.07 12.8 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain Asp_Glu_race PF01177.17 KPI38667.1 - 7.4e-27 94.6 0.1 8.5e-27 94.4 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase UPF0086 PF01868.11 KPI38668.1 - 6.3e-22 77.0 0.5 9.4e-22 76.4 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Lactonase PF10282.4 KPI38668.1 - 0.018 14.1 0.4 0.029 13.4 0.0 1.4 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Allantoicase PF03561.10 KPI38668.1 - 0.063 12.7 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Allantoicase repeat HLH PF00010.21 KPI38669.1 - 3.8e-07 29.6 2.4 8.3e-07 28.6 1.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain mTERF PF02536.9 KPI38669.1 - 0.013 14.1 0.4 0.017 13.6 0.3 1.1 1 0 0 1 1 1 0 mTERF DUF1664 PF07889.7 KPI38669.1 - 0.037 13.8 1.7 0.06 13.1 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) RNA_pol_Rpb8 PF03870.10 KPI38670.1 - 3.1e-32 111.6 0.0 3.8e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Phosducin PF02114.11 KPI38672.1 - 4.7e-06 25.5 0.0 0.0044 15.7 0.0 2.3 2 0 0 2 2 2 2 Phosducin SpoIIIAH PF12685.2 KPI38672.1 - 0.54 9.7 4.1 1.8 8.0 0.8 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein WD40 PF00400.27 KPI38673.1 - 3.1e-55 182.1 14.8 6.2e-10 38.5 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KPI38673.1 - 0.00045 18.4 5.9 8.3 4.4 0.0 4.8 1 1 4 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KPI38673.1 - 0.00056 19.4 0.5 0.72 9.2 0.0 2.8 2 1 0 3 3 3 2 PQQ-like domain Nucleoporin_N PF08801.6 KPI38673.1 - 0.029 13.1 0.1 5.6 5.6 0.0 3.3 1 1 1 3 3 3 0 Nup133 N terminal like RRN3 PF05327.6 KPI38674.1 - 1e-131 439.8 1.0 1.2e-131 439.6 0.7 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Integrase_DNA PF02920.10 KPI38674.1 - 0.043 13.2 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase EXOSC1 PF10447.4 KPI38675.1 - 6e-21 74.2 0.1 9e-21 73.6 0.1 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 KPI38675.1 - 2.1e-10 39.6 0.2 4.8e-10 38.5 0.2 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Glyco_transf_15 PF01793.11 KPI38676.1 - 4.3e-33 114.6 0.0 5.3e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase UDPGP PF01704.13 KPI38676.1 - 0.052 12.0 0.0 0.063 11.7 0.0 1.0 1 0 0 1 1 1 0 UTP--glucose-1-phosphate uridylyltransferase Fungal_trans_2 PF11951.3 KPI38677.1 - 5.1e-07 28.6 1.7 2e-06 26.6 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Integrin_b_cyt PF08725.6 KPI38677.1 - 0.09 12.1 0.2 0.25 10.7 0.2 1.8 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain GSHPx PF00255.14 KPI38678.1 - 8.5e-38 128.0 0.1 1.1e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KPI38678.1 - 0.0019 17.8 0.3 0.009 15.6 0.2 2.1 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KPI38678.1 - 0.016 14.7 0.9 0.14 11.7 0.6 2.2 1 1 0 1 1 1 0 Redoxin ArfGap PF01412.13 KPI38679.1 - 1.8e-34 118.0 0.2 3.2e-34 117.2 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf AflR PF08493.5 KPI38679.1 - 2.9 6.8 7.9 0.25 10.3 0.1 2.2 2 0 0 2 2 2 0 Aflatoxin regulatory protein Syja_N PF02383.13 KPI38680.1 - 9.6e-88 294.0 0.0 1.4e-87 293.4 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 KPI38680.1 - 3.2e-33 113.5 0.4 8.9e-33 112.0 0.0 1.9 2 0 0 2 2 2 1 Inositol phosphatase Scm3 PF10384.4 KPI38680.1 - 0.015 14.7 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 0 Centromere protein Scm3 tRNA_SAD PF07973.9 KPI38681.1 - 2.6e-05 24.0 0.6 6.1e-05 22.8 0.4 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 KPI38681.1 - 5.2e-05 21.7 0.0 7e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) zf-DHHC PF01529.15 KPI38682.1 - 2.5e-40 137.7 6.7 2.8e-40 137.5 3.4 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Acetyltransf_7 PF13508.1 KPI38682.1 - 8.5e-07 29.0 0.0 1.9e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KPI38682.1 - 8.4e-06 25.7 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KPI38682.1 - 0.00095 19.0 0.0 0.0039 17.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI38682.1 - 0.0013 18.8 0.0 0.0034 17.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KPI38682.1 - 0.029 14.2 0.0 0.079 12.8 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DZR PF12773.2 KPI38682.1 - 0.36 10.6 12.8 0.036 13.8 5.2 1.9 2 0 0 2 2 2 0 Double zinc ribbon DUF4336 PF14234.1 KPI38683.1 - 5.6e-19 68.4 0.0 2.9e-14 52.9 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) An_peroxidase PF03098.10 KPI38684.1 - 6.2e-104 348.2 0.0 3e-80 270.1 0.0 2.0 1 1 1 2 2 2 2 Animal haem peroxidase MKT1_C PF12246.3 KPI38685.1 - 7.6e-46 156.0 0.0 1.3e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 KPI38685.1 - 3.3e-20 72.1 0.0 1.2e-19 70.3 0.0 2.0 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication 2OG-FeII_Oxy PF03171.15 KPI38685.1 - 9.4e-17 61.1 0.0 3.1e-16 59.4 0.0 2.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KPI38685.1 - 2.1e-15 57.2 0.1 1.2e-14 54.8 0.0 2.4 2 1 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal XPG_I PF00867.13 KPI38685.1 - 8e-09 35.4 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 XPG I-region RCC1_2 PF13540.1 KPI38685.1 - 9.6e-09 34.6 12.1 0.001 18.6 0.0 4.6 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat zf-C3HC4 PF00097.20 KPI38686.1 - 6.1e-09 35.4 10.8 6.1e-09 35.4 7.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI38686.1 - 2.5e-08 33.8 11.2 2.5e-08 33.8 7.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KPI38686.1 - 1e-07 31.4 8.6 1e-07 31.4 6.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI38686.1 - 3.2e-07 29.9 10.5 3.2e-07 29.9 7.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 KPI38686.1 - 3.5e-07 29.9 2.6 3.5e-07 29.9 1.8 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 KPI38686.1 - 6.1e-07 29.1 10.4 6.1e-07 29.1 7.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 KPI38686.1 - 7.8e-06 25.5 7.0 2e-05 24.1 4.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 KPI38686.1 - 7.2e-05 22.8 5.3 0.00018 21.5 3.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KPI38686.1 - 0.00022 21.0 12.7 0.00029 20.6 7.4 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.10 KPI38686.1 - 0.00026 20.9 0.5 0.001 18.9 0.0 2.2 2 0 0 2 2 2 1 U-box domain Sgf11 PF08209.6 KPI38686.1 - 0.00057 19.1 0.1 0.00057 19.1 0.1 2.0 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) SAP PF02037.22 KPI38686.1 - 0.00075 18.9 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-RING_4 PF14570.1 KPI38686.1 - 0.0016 18.0 2.8 0.0016 18.0 1.9 2.7 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain Mob_synth_C PF06463.8 KPI38686.1 - 0.0023 17.6 2.4 0.0064 16.1 1.6 1.7 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Barttin PF15462.1 KPI38686.1 - 0.0066 16.1 1.7 0.017 14.8 1.2 1.6 1 0 0 1 1 1 1 Bartter syndrome, infantile, with sensorineural deafness (Barttin) zf-Apc11 PF12861.2 KPI38686.1 - 0.025 14.3 2.3 0.067 13.0 1.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 KPI38686.1 - 0.057 12.9 6.8 0.12 11.8 4.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ribosomal_L37e PF01907.14 KPI38686.1 - 0.083 12.7 1.1 0.21 11.4 0.8 1.7 1 0 0 1 1 1 0 Ribosomal protein L37e zinc-ribbons_6 PF07191.7 KPI38686.1 - 1.8 8.4 10.0 25 4.7 4.4 2.7 2 1 0 2 2 2 0 zinc-ribbons DUF1272 PF06906.6 KPI38686.1 - 4.1 7.3 11.1 1.3 8.9 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-P11 PF03854.9 KPI38686.1 - 6.1 6.3 9.0 28 4.2 5.5 2.3 1 1 1 2 2 2 0 P-11 zinc finger Metallophos PF00149.23 KPI38687.1 - 3.5e-41 140.8 0.6 3.9e-41 140.6 0.4 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.20 KPI38688.1 - 7.2e-60 202.3 0.0 2.3e-59 200.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI38688.1 - 6.1e-26 91.0 0.0 5.4e-18 64.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KPI38688.1 - 0.00017 20.6 0.0 0.15 11.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KPI38688.1 - 0.023 13.7 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mob1_phocein PF03637.12 KPI38690.1 - 1.1e-22 80.5 3.3 3.5e-14 52.8 0.3 2.7 2 1 1 3 3 3 2 Mob1/phocein family HABP4_PAI-RBP1 PF04774.10 KPI38691.1 - 0.0059 17.0 2.8 0.012 16.1 2.0 1.6 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family GST_N_3 PF13417.1 KPI38693.1 - 1.1e-11 44.8 0.0 2.6e-11 43.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI38693.1 - 3e-08 33.5 0.1 5.3e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KPI38693.1 - 0.0004 20.7 0.0 0.00082 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI38693.1 - 0.046 13.6 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KPI38693.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF104 PF01954.11 KPI38694.1 - 0.054 13.5 0.1 0.17 11.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF104 MG1 PF11974.3 KPI38694.1 - 1.5 9.4 7.2 3.7 8.1 0.8 2.8 2 0 0 2 2 2 0 Alpha-2-macroglobulin MG1 domain RSN1_TM PF13967.1 KPI38695.1 - 9.2e-41 139.0 0.6 1.7e-40 138.1 0.4 1.4 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KPI38695.1 - 1.6e-11 44.5 0.9 7.9e-06 26.3 0.4 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) HECA PF15353.1 KPI38695.1 - 0.066 12.9 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Headcase protein family homologue Trypan_PARP PF05887.6 KPI38696.1 - 3.5 7.4 8.8 0.35 10.6 3.0 1.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Atrophin-1 PF03154.10 KPI38696.1 - 7.8 4.4 9.4 11 4.0 6.5 1.2 1 0 0 1 1 1 0 Atrophin-1 family RNA_pol_Rpc34 PF05158.7 KPI38697.1 - 7.4e-60 202.8 0.0 1.2e-59 202.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit FMN_red PF03358.10 KPI38698.1 - 1.7e-09 37.3 0.0 2.4e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 KPI38698.1 - 2.8e-08 33.8 0.6 1.1e-07 31.9 0.2 2.1 2 1 0 2 2 2 1 Flavodoxin Flavodoxin_2 PF02525.12 KPI38698.1 - 0.033 13.6 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin-like fold Flavodoxin_5 PF12724.2 KPI38698.1 - 0.048 13.6 0.0 4.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Flavodoxin domain Nucleotid_trans PF03407.11 KPI38699.1 - 1.1e-15 57.9 0.4 2e-15 57.1 0.3 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Pmp3 PF01679.12 KPI38699.1 - 1.2e-10 40.9 0.7 2.1e-10 40.1 0.5 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator bZIP_1 PF00170.16 KPI38700.1 - 1.5e-05 24.8 5.7 2.7e-05 24.0 3.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KPI38700.1 - 0.0015 18.3 6.9 0.0024 17.6 4.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KPI38700.1 - 0.006 16.8 4.1 0.011 16.0 2.8 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor LTXXQ PF07813.7 KPI38700.1 - 2.5 8.6 5.3 20 5.7 1.6 2.2 2 0 0 2 2 2 0 LTXXQ motif family protein DUF2416 PF10315.4 KPI38702.1 - 0.027 14.7 0.2 0.04 14.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2416) Atg8 PF02991.11 KPI38703.1 - 2.6e-51 171.9 0.2 3.1e-51 171.6 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KPI38703.1 - 2.6e-06 27.5 0.0 3.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 RTA1 PF04479.8 KPI38704.1 - 9.1e-32 110.3 2.2 1.4e-31 109.7 1.5 1.2 1 0 0 1 1 1 1 RTA1 like protein TraH_2 PF06871.6 KPI38704.1 - 0.29 10.5 0.8 3.4 7.0 0.1 2.0 2 0 0 2 2 2 0 TraH_2 FAD-oxidase_C PF02913.14 KPI38705.1 - 1.3e-58 198.2 0.1 1.9e-58 197.7 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KPI38705.1 - 2.6e-37 127.4 0.0 4.6e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AAA_23 PF13476.1 KPI38706.1 - 6.8e-22 78.7 0.3 6.8e-22 78.7 0.2 7.5 1 1 2 3 3 3 1 AAA domain SbcCD_C PF13558.1 KPI38706.1 - 4.2e-11 42.6 0.0 1.8e-10 40.5 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 KPI38706.1 - 3.1e-10 40.4 1.0 0.0014 18.6 0.0 3.7 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 KPI38706.1 - 4.8e-05 22.6 46.2 0.00099 18.4 32.0 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KPI38706.1 - 0.00084 18.8 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 KPI38706.1 - 0.21 11.3 2.6 0.33 10.7 0.5 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_13 PF13166.1 KPI38706.1 - 5.1 5.4 124.7 0.023 13.2 18.3 6.9 2 1 5 7 7 7 0 AAA domain Dynactin_p62 PF05502.8 KPI38707.1 - 5.6e-114 381.5 0.6 9e-112 374.2 0.2 2.1 1 1 1 2 2 2 2 Dynactin p62 family DEAD PF00270.24 KPI38709.1 - 6.8e-19 67.9 0.9 2.1e-17 63.1 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI38709.1 - 8e-08 32.0 0.0 1.8e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 KPI38709.1 - 4.9e-05 23.4 0.2 0.00015 21.8 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain ResIII PF04851.10 KPI38709.1 - 0.00037 20.3 0.0 0.00071 19.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4332 PF14229.1 KPI38709.1 - 0.0037 17.2 0.1 0.0084 16.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) AAA_22 PF13401.1 KPI38709.1 - 0.051 13.7 0.2 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain UPF0561 PF10573.4 KPI38711.1 - 0.09 12.6 0.2 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 MT0933_antitox PF14013.1 KPI38711.1 - 7.2 6.7 7.6 14 5.8 5.3 1.7 1 1 0 1 1 1 0 MT0933-like antitoxin protein FAD_binding_4 PF01565.18 KPI38712.1 - 3.2e-17 62.3 0.0 6.4e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Fungal_trans PF04082.13 KPI38713.1 - 3.4e-22 78.5 1.6 6.5e-22 77.6 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI38713.1 - 0.00024 20.9 11.6 0.00055 19.7 8.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NT-C2 PF10358.4 KPI38716.1 - 3.2e-29 101.2 0.0 5.3e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Ribosomal_L37e PF01907.14 KPI38717.1 - 2.6e-27 94.3 12.4 3.9e-27 93.7 8.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 KPI38717.1 - 0.0018 18.0 1.2 0.0027 17.4 0.8 1.2 1 0 0 1 1 1 1 Double zinc ribbon FdhE PF04216.7 KPI38717.1 - 0.045 13.4 1.5 0.046 13.4 1.0 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-ribbon_3 PF13248.1 KPI38717.1 - 0.1 11.8 2.1 1 8.6 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KPI38717.1 - 0.24 10.9 3.2 4.2 6.9 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.20 KPI38717.1 - 0.35 10.5 4.4 0.55 9.9 3.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HYPF PF07503.7 KPI38717.1 - 5.6 6.4 6.6 0.75 9.2 0.5 2.1 1 1 1 2 2 2 0 HypF finger TFIIA PF03153.8 KPI38718.1 - 4.8 6.9 11.0 6.9 6.4 7.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GPI2 PF06432.6 KPI38722.1 - 1.9e-102 342.4 1.9 2.9e-102 341.7 1.3 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase 2TM PF13239.1 KPI38722.1 - 0.19 11.8 0.0 0.19 11.8 0.0 3.0 3 0 0 3 3 3 0 2TM domain DUF221 PF02714.10 KPI38724.1 - 1.5e-83 280.3 34.0 1.9e-83 280.0 23.6 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF3779 PF12621.3 KPI38724.1 - 2.3e-14 53.0 0.0 4.8e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein Thiolase_C PF02803.13 KPI38726.1 - 8.9e-13 47.7 0.1 2e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KPI38726.1 - 1.2e-07 31.2 0.1 1.6e-05 24.5 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KPI38726.1 - 3.9e-07 29.3 0.1 2.2e-06 26.8 0.0 2.2 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 KPI38726.1 - 4.2e-05 23.1 0.1 0.00017 21.1 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KPI38726.1 - 0.0067 16.2 0.2 0.073 12.9 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain AMP-binding PF00501.23 KPI38727.1 - 6.8e-69 232.2 0.0 8.3e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI38727.1 - 8.5e-16 58.6 0.0 2.2e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GATA PF00320.22 KPI38728.1 - 1.7e-16 59.2 5.2 3.2e-16 58.3 3.6 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 KPI38728.1 - 7.2e-12 45.2 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 KPI38728.1 - 9e-10 38.8 0.0 2.3e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 KPI38728.1 - 5.5e-09 35.8 0.0 8.8e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 KPI38728.1 - 5.6e-08 32.8 0.0 1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold DUF4428 PF14471.1 KPI38728.1 - 1.7 8.4 5.4 0.3 10.8 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) 2-Hacid_dh_C PF02826.14 KPI38729.1 - 2.1e-55 186.6 0.0 2.7e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KPI38729.1 - 2.6e-17 62.5 0.0 4e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KPI38729.1 - 0.00051 19.9 0.1 0.001 18.9 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 KPI38729.1 - 0.0011 18.8 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.12 KPI38729.1 - 0.05 14.0 0.4 0.11 12.9 0.3 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Abhydrolase_3 PF07859.8 KPI38730.1 - 7e-33 113.9 0.0 1e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI38730.1 - 1.9e-05 24.6 0.0 2.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KPI38730.1 - 0.00052 18.8 0.0 0.00089 18.0 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Amidase PF01425.16 KPI38731.1 - 1.6e-90 304.1 0.0 2.2e-90 303.6 0.0 1.2 1 0 0 1 1 1 1 Amidase TPR_11 PF13414.1 KPI38732.1 - 5.3e-56 186.1 23.6 1e-17 63.4 0.3 6.3 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 KPI38732.1 - 1.4e-45 151.0 21.9 1.4e-05 24.4 0.1 9.2 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 KPI38732.1 - 4e-39 129.3 19.1 7.9e-06 25.4 0.1 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 KPI38732.1 - 3.2e-21 75.4 9.3 0.0014 19.2 0.0 6.6 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 KPI38732.1 - 1.3e-18 66.7 16.1 5.4e-10 39.0 0.1 6.0 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KPI38732.1 - 5.1e-17 60.8 14.9 0.14 12.8 0.2 9.4 5 3 5 10 10 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 KPI38732.1 - 5.5e-14 50.8 20.0 0.013 15.1 0.1 8.4 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 KPI38732.1 - 5.3e-12 44.9 10.7 0.0022 18.0 0.0 8.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 KPI38732.1 - 4.5e-11 42.9 20.4 0.029 14.7 0.1 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 KPI38732.1 - 3.7e-10 39.4 0.7 0.014 15.2 0.1 5.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KPI38732.1 - 4.1e-09 35.5 13.1 0.0026 17.4 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KPI38732.1 - 1.2e-07 31.6 13.2 0.0025 17.9 0.5 3.9 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 KPI38732.1 - 1e-05 25.2 5.0 0.43 10.5 0.0 5.9 6 1 1 7 7 7 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KPI38732.1 - 0.00021 21.5 23.7 0.37 11.3 0.0 8.4 10 0 0 10 10 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 KPI38732.1 - 0.039 13.8 5.2 31 4.6 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 KPI38732.1 - 0.062 13.4 14.9 0.41 10.8 0.0 5.0 4 2 0 5 5 5 0 Tetratricopeptide repeat Inhibitor_I9 PF05922.11 KPI38732.1 - 0.1 13.1 0.0 0.48 11.0 0.0 2.2 1 0 0 1 1 1 0 Peptidase inhibitor I9 RPN7 PF10602.4 KPI38732.1 - 0.41 10.0 0.0 0.41 10.0 0.0 4.2 5 1 2 7 7 7 0 26S proteasome subunit RPN7 NSF PF02071.15 KPI38732.1 - 0.92 10.3 3.7 33 5.7 0.1 4.3 3 0 0 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat Chromate_transp PF02417.10 KPI38733.1 - 3.4e-49 166.7 33.7 9.8e-29 100.1 7.5 2.6 3 0 0 3 3 3 2 Chromate transporter CcmH PF03918.9 KPI38733.1 - 0.064 12.2 6.0 0.18 10.7 0.2 3.2 3 0 0 3 3 3 0 Cytochrome C biogenesis protein DUF3329 PF11808.3 KPI38733.1 - 0.072 13.1 0.3 0.37 10.8 0.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) PTPS_related PF10131.4 KPI38733.1 - 1.5 6.8 7.4 2.7 6.0 2.1 2.2 2 0 0 2 2 2 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Clr5 PF14420.1 KPI38734.1 - 2.2e-20 72.3 0.4 9.4e-20 70.2 0.0 2.3 2 0 0 2 2 2 1 Clr5 domain Ufd2P_core PF10408.4 KPI38735.1 - 6.8e-190 632.4 8.4 8.6e-190 632.1 5.9 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KPI38735.1 - 1.2e-25 89.2 1.6 1.2e-25 89.2 1.1 2.1 2 0 0 2 2 2 1 U-box domain DS PF01916.12 KPI38736.1 - 4.6e-141 469.1 0.0 5.5e-141 468.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 KPI38736.1 - 0.072 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase Calpain_inhib PF00748.14 KPI38737.1 - 1 9.7 6.7 1.5 9.1 4.3 1.6 1 1 0 1 1 1 0 Calpain inhibitor TFIIA PF03153.8 KPI38737.1 - 7.5 6.3 12.4 8.5 6.1 8.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Het-C PF07217.6 KPI38738.1 - 2.1e-254 845.3 0.2 1.1e-253 842.9 0.1 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Abhydrolase_6 PF12697.2 KPI38739.1 - 1.4e-07 31.6 0.0 3.5e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI38739.1 - 3.2e-05 23.6 0.0 5.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI38739.1 - 0.00039 20.1 0.0 0.00089 19.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 KPI38739.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Macro PF01661.16 KPI38740.1 - 4.2e-15 55.6 0.1 2.5e-14 53.2 0.1 1.9 1 1 0 1 1 1 1 Macro domain DUF2970 PF11174.3 KPI38741.1 - 0.0047 16.4 0.6 0.0073 15.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2970) Shugoshin_C PF07557.6 KPI38741.1 - 0.012 15.0 1.1 0.012 15.0 0.8 2.4 2 0 0 2 2 2 0 Shugoshin C terminus DUF3770 PF12603.3 KPI38741.1 - 0.054 12.5 0.1 0.086 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) SoxE PF06525.6 KPI38741.1 - 0.084 12.1 0.4 0.17 11.1 0.3 1.5 1 0 0 1 1 1 0 Sulfocyanin (SoxE) DUF2015 PF09435.5 KPI38741.1 - 0.1 12.3 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) P16-Arc PF04699.9 KPI38742.1 - 3.6e-37 127.7 0.0 4.4e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Acetyltransf_3 PF13302.1 KPI38743.1 - 5.4e-36 123.8 0.0 7.6e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain QCR10 PF09796.4 KPI38743.1 - 5.4e-27 93.2 1.0 1e-26 92.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Acetyltransf_4 PF13420.1 KPI38743.1 - 2.7e-12 46.9 0.0 5e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KPI38743.1 - 5.1e-10 39.4 0.2 6.3e-09 35.8 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KPI38743.1 - 7.2e-06 25.9 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KPI38743.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Fe-ADH PF00465.14 KPI38744.1 - 4.7e-69 232.7 0.0 5.7e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KPI38744.1 - 0.00015 21.1 0.0 0.0006 19.1 0.0 1.8 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase CobN-Mg_chel PF02514.11 KPI38744.1 - 0.086 10.2 0.0 0.11 9.8 0.0 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase DUF4310 PF14187.1 KPI38744.1 - 0.095 12.1 0.2 0.16 11.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) Abhydrolase_6 PF12697.2 KPI38745.1 - 2.3e-28 99.6 0.5 4.7e-28 98.6 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI38745.1 - 9.4e-06 25.3 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI38745.1 - 3.1e-05 23.7 0.0 4.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Aldedh PF00171.17 KPI38746.1 - 1.1e-142 475.6 0.0 1.3e-142 475.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KPI38746.1 - 0.00015 20.6 0.1 0.00047 18.9 0.1 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KPI38746.1 - 0.00022 20.5 0.0 0.05 12.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) DUF1712 PF08217.6 KPI38747.1 - 1.1e-16 60.2 0.0 4.9e-12 44.9 0.0 3.0 3 0 0 3 3 3 3 Fungal domain of unknown function (DUF1712) Zn_clus PF00172.13 KPI38749.1 - 3.2e-09 36.5 10.4 5.1e-09 35.8 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KPI38749.1 - 0.03 12.9 0.4 0.046 12.3 0.3 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain RPE65 PF03055.10 KPI38750.1 - 3.2e-105 352.5 0.0 4.5e-104 348.7 0.0 2.0 1 1 0 1 1 1 1 Retinal pigment epithelial membrane protein PPI_Ypi1 PF07491.6 KPI38750.1 - 0.028 14.0 0.2 0.069 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein phosphatase inhibitor Ribosomal_60s PF00428.14 KPI38751.1 - 1.2e-07 31.9 0.0 1.7e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cupin_2 PF07883.6 KPI38752.1 - 5.5e-06 25.7 0.7 4.7e-05 22.8 0.1 2.7 2 1 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 KPI38752.1 - 0.006 16.0 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Cupin Glyco_transf_90 PF05686.7 KPI38753.1 - 2.3e-23 82.5 0.3 3.3e-23 82.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 KPI38753.1 - 1.2e-05 25.4 0.0 2.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF4296 PF14129.1 KPI38753.1 - 0.14 12.3 0.2 0.26 11.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) MFS_1 PF07690.11 KPI38754.1 - 6.9e-40 136.8 34.2 9.4e-40 136.3 23.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI38754.1 - 9.9e-17 60.6 18.9 2.1e-16 59.5 13.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KPI38754.1 - 2.2e-08 32.7 2.3 2.2e-08 32.7 1.6 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Gly-zipper_OmpA PF13436.1 KPI38754.1 - 0.0071 15.9 1.9 0.23 11.1 0.2 2.6 2 0 0 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain OATP PF03137.15 KPI38754.1 - 0.014 13.4 0.6 0.64 8.0 0.2 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family IncA PF04156.9 KPI38754.1 - 0.35 10.4 0.0 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 IncA protein DUF4112 PF13430.1 KPI38754.1 - 0.51 10.2 0.0 0.51 10.2 0.0 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4112) SpoIIIAH PF12685.2 KPI38754.1 - 7.6 5.9 15.1 3 7.2 6.1 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF3328 PF11807.3 KPI38755.1 - 3.4e-22 79.1 1.0 7.3e-22 78.1 0.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) RRM_1 PF00076.17 KPI38756.1 - 7.3e-10 38.3 0.0 1.7e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI38756.1 - 7.3e-09 35.4 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KPI38756.1 - 0.00013 21.6 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KPI38756.1 - 0.01 15.6 0.4 0.033 14.0 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif DUF629 PF04780.7 KPI38756.1 - 0.13 10.7 0.1 0.19 10.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Peptidase_M35 PF02102.10 KPI38757.1 - 3.7e-95 318.6 11.3 4.6e-95 318.3 7.8 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 KPI38757.1 - 1e-12 48.8 0.5 1.6e-12 48.1 0.3 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase cNMP_binding PF00027.24 KPI38759.1 - 2.8e-36 123.1 0.0 4.2e-21 74.5 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain p450 PF00067.17 KPI38759.1 - 2.1e-25 89.1 0.0 6.7e-25 87.5 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 LRR_6 PF13516.1 KPI38759.1 - 3.9e-11 41.8 5.7 0.068 13.2 0.1 7.9 7 0 0 7 7 7 2 Leucine Rich repeat LRR_8 PF13855.1 KPI38759.1 - 6.1e-05 22.7 0.3 0.0041 16.8 0.0 3.7 4 0 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.28 KPI38759.1 - 0.00025 20.6 5.0 56 4.3 0.0 7.4 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_4 PF12799.2 KPI38759.1 - 0.00042 19.8 0.1 0.5 10.0 0.0 4.2 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KPI38759.1 - 0.0085 15.8 1.4 0.013 15.2 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KPI38759.1 - 0.056 13.1 2.9 0.1 12.2 0.2 2.8 2 0 0 2 2 2 0 F-box domain LRR_7 PF13504.1 KPI38759.1 - 3.3 8.3 12.9 53 4.6 0.0 6.4 7 0 0 7 7 7 0 Leucine rich repeat E1-E2_ATPase PF00122.15 KPI38762.1 - 2.5e-61 206.6 2.6 4.2e-61 205.9 1.8 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KPI38762.1 - 2.7e-31 108.4 8.5 2.7e-31 108.4 5.9 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KPI38762.1 - 3.9e-28 99.3 0.0 4.8e-27 95.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KPI38762.1 - 6.5e-18 63.9 0.0 1.3e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KPI38762.1 - 3.1e-15 55.8 0.0 6.6e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KPI38762.1 - 2.1e-14 54.1 0.1 7.7e-14 52.2 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KPI38762.1 - 2.7e-05 23.9 0.2 0.001 18.7 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PPP4R2 PF09184.6 KPI38763.1 - 6.6e-11 42.2 0.6 4.1e-10 39.6 0.0 2.3 2 0 0 2 2 2 1 PPP4R2 Cupin_8 PF13621.1 KPI38764.1 - 5.1e-23 81.8 0.0 6.2e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KPI38764.1 - 0.0014 18.8 0.0 0.0073 16.5 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 KPI38764.1 - 0.0069 15.8 0.0 0.021 14.2 0.0 1.7 2 0 0 2 2 2 1 Cupin domain C2 PF00168.25 KPI38765.1 - 7.4e-59 195.5 0.2 3.5e-16 58.8 0.0 5.6 5 0 0 5 5 5 5 C2 domain ING PF12998.2 KPI38765.1 - 2.9e-13 50.0 4.9 7.3e-13 48.7 3.4 1.8 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding adh_short PF00106.20 KPI38766.1 - 2.1e-27 96.0 2.6 3.3e-27 95.4 1.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI38766.1 - 1.8e-23 83.5 0.6 2.5e-23 83.1 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI38766.1 - 1.3e-12 47.7 0.7 2.2e-12 47.0 0.5 1.3 1 0 0 1 1 1 1 KR domain GDPD_2 PF13653.1 KPI38766.1 - 0.11 12.6 0.0 7.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family ETC_C1_NDUFA5 PF04716.9 KPI38768.1 - 1.2e-17 63.2 3.0 3e-17 61.8 0.4 2.4 2 0 0 2 2 2 1 ETC complex I subunit conserved region LEA_1 PF03760.10 KPI38768.1 - 0.014 15.5 0.4 0.025 14.7 0.3 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant (LEA) group 1 Aldedh PF00171.17 KPI38769.1 - 8.4e-131 436.4 2.8 8.9e-85 284.7 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 KPI38769.1 - 2.3e-05 23.2 0.0 0.067 11.8 0.0 2.4 2 1 0 2 2 2 2 Acyl-CoA reductase (LuxC) Phage_Mu_Gam PF07352.7 KPI38769.1 - 0.66 9.4 2.4 0.67 9.4 0.4 1.8 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein MFS_1 PF07690.11 KPI38771.1 - 1.8e-28 99.2 56.7 1e-14 54.0 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI38771.1 - 7.1e-05 21.3 24.5 0.00025 19.5 17.0 1.8 1 1 0 1 1 1 1 MFS/sugar transport protein stn_TNFRSF12A PF12191.3 KPI38771.1 - 0.074 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Glyco_hydro_47 PF01532.15 KPI38772.1 - 1.9e-151 504.7 0.0 2.2e-151 504.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Reticulon PF02453.12 KPI38773.1 - 2.2e-08 33.9 0.7 3.9e-08 33.0 0.5 1.3 1 0 0 1 1 1 1 Reticulon Tape_meas_lam_C PF09718.5 KPI38773.1 - 1.4 8.9 5.3 3.8 7.5 0.3 2.7 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Abhydrolase_6 PF12697.2 KPI38774.1 - 3.6e-18 66.2 0.2 7.6e-18 65.2 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI38774.1 - 5.9e-13 48.8 0.1 7.6e-13 48.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KPI38774.1 - 0.00091 19.5 0.0 0.022 14.9 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Peptidase_S9 PF00326.16 KPI38774.1 - 0.0091 15.2 0.1 0.15 11.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KPI38774.1 - 0.022 14.3 0.1 0.041 13.4 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold ATP-synt_C PF00137.16 KPI38775.1 - 4.1e-17 61.8 14.5 1e-16 60.5 10.0 1.7 1 0 0 1 1 1 1 ATP synthase subunit C MFS_3 PF05977.8 KPI38775.1 - 0.088 10.9 4.4 0.11 10.5 3.1 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector DUF3353 PF11833.3 KPI38775.1 - 0.14 11.6 1.9 0.16 11.4 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) AhpC-TSA PF00578.16 KPI38776.1 - 4e-19 68.5 0.0 6.4e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KPI38776.1 - 6.5e-12 45.2 0.0 9.9e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.7 KPI38776.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Ras PF00071.17 KPI38777.1 - 4.8e-49 165.8 0.0 2.3e-48 163.6 0.0 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KPI38777.1 - 1.7e-13 51.0 0.0 3.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KPI38777.1 - 0.0014 17.8 0.0 0.0021 17.2 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region 2OG-FeII_Oxy_2 PF13532.1 KPI38778.1 - 5.9e-14 52.3 0.0 1.6e-12 47.6 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KPI38778.1 - 1.9e-07 31.2 0.0 4.1e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KPI38778.1 - 0.0043 17.5 0.0 0.01 16.3 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aa_trans PF01490.13 KPI38779.1 - 1.2e-27 96.5 31.3 3.8e-11 42.1 4.0 4.0 2 2 1 3 3 3 3 Transmembrane amino acid transporter protein MFS_1 PF07690.11 KPI38781.1 - 8.1e-25 87.2 36.1 2e-24 85.9 22.3 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily ubiquitin PF00240.18 KPI38782.1 - 1.8e-05 24.0 0.0 3.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KPI38782.1 - 0.0028 17.8 0.4 0.0068 16.5 0.2 1.7 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Hemocyanin_M PF00372.14 KPI38782.1 - 0.041 13.1 0.2 0.063 12.5 0.1 1.1 1 0 0 1 1 1 0 Hemocyanin, copper containing domain PfUIS3 PF11567.3 KPI38782.1 - 0.042 14.0 1.4 0.078 13.1 1.0 1.3 1 0 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein ALAD PF00490.16 KPI38783.1 - 6.3e-100 334.2 0.0 7.3e-100 334.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase zf-HC5HC2H_2 PF13832.1 KPI38784.1 - 9.9e-16 57.7 0.2 9.9e-16 57.7 0.1 3.7 3 0 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KPI38784.1 - 4.2e-15 55.6 0.2 4.2e-15 55.6 0.1 4.5 4 1 0 4 4 4 1 PHD-like zinc-binding domain BAH PF01426.13 KPI38784.1 - 1.5e-13 50.4 0.1 3.6e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 KPI38784.1 - 1.7e-11 43.6 46.0 5.6e-07 29.1 3.6 5.5 5 0 0 5 5 5 2 PHD-finger PHD_2 PF13831.1 KPI38784.1 - 2.5e-08 33.1 3.6 2.5e-08 33.1 2.5 4.8 4 0 0 4 4 4 2 PHD-finger Prok-RING_1 PF14446.1 KPI38784.1 - 0.0012 18.5 3.6 0.0012 18.5 2.5 5.1 4 1 0 4 4 4 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 KPI38784.1 - 0.0024 17.5 1.1 0.0024 17.5 0.7 6.2 6 1 1 7 7 7 2 Phorbol esters/diacylglycerol binding domain (C1 domain) ABC_membrane PF00664.18 KPI38785.1 - 1.7e-70 237.5 38.4 3.1e-37 128.5 8.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KPI38785.1 - 5.1e-62 208.1 0.0 2.6e-33 115.2 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KPI38785.1 - 5.2e-17 61.8 1.0 5.1e-05 22.6 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KPI38785.1 - 2.2e-13 50.8 0.1 0.0036 17.3 0.0 4.3 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.1 KPI38785.1 - 2.6e-09 37.3 4.1 5.1e-05 23.3 0.0 3.7 4 0 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.1 KPI38785.1 - 3.6e-08 33.6 1.0 0.079 13.1 0.0 4.6 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KPI38785.1 - 1.8e-07 30.5 0.7 0.00011 21.6 0.2 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KPI38785.1 - 2.9e-07 31.3 0.0 0.0094 16.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KPI38785.1 - 3.7e-07 29.0 0.5 0.0069 15.0 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 KPI38785.1 - 9.5e-07 28.1 0.0 0.0095 15.1 0.0 2.6 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KPI38785.1 - 1.4e-05 25.4 0.5 0.0042 17.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KPI38785.1 - 3.7e-05 23.9 1.3 3 8.0 0.0 4.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KPI38785.1 - 0.00012 21.8 0.1 2.5 7.7 0.0 3.4 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KPI38785.1 - 0.0002 21.2 1.9 0.22 11.4 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 KPI38785.1 - 0.00026 20.4 2.6 0.45 9.8 0.0 3.4 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.1 KPI38785.1 - 0.00092 18.8 0.2 5.5 6.5 0.0 4.0 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.1 KPI38785.1 - 0.0014 18.9 0.0 1.2 9.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KPI38785.1 - 0.0017 18.2 0.0 1.2 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KPI38785.1 - 0.002 17.8 0.1 3.7 7.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KPI38785.1 - 0.0073 16.0 0.0 1.4 8.6 0.0 3.5 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 KPI38785.1 - 0.011 15.6 0.5 5.9 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KPI38785.1 - 0.018 15.2 0.0 7.1 6.8 0.0 2.8 2 0 0 2 2 2 0 RNA helicase ATP-synt_ab PF00006.20 KPI38785.1 - 0.048 13.1 0.1 4.2 6.7 0.0 3.2 4 0 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 KPI38785.1 - 0.074 11.7 0.1 8.5 4.9 0.0 2.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KPI38785.1 - 0.075 12.9 0.0 19 5.1 0.0 3.8 5 0 0 5 5 4 0 AAA domain ATP_bind_1 PF03029.12 KPI38785.1 - 0.11 11.9 0.1 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 KPI38785.1 - 0.13 11.8 0.1 20 4.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KPI38785.1 - 0.23 10.8 7.7 0.5 9.7 0.1 4.0 5 0 0 5 5 5 0 AAA-like domain AAA_15 PF13175.1 KPI38785.1 - 0.43 9.5 0.0 8.5 5.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain HMGL-like PF00682.14 KPI38786.1 - 3.2e-63 213.5 0.0 5e-63 212.9 0.0 1.3 1 0 0 1 1 1 1 HMGL-like DUF2985 PF11204.3 KPI38786.1 - 2.7e-36 123.1 1.2 5.8e-36 122.1 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) LeuA_dimer PF08502.5 KPI38786.1 - 2.5e-22 79.1 0.0 6.3e-22 77.7 0.0 1.8 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain AMP-binding PF00501.23 KPI38787.1 - 1.5e-50 171.8 0.0 2.1e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme TrkA_N PF02254.13 KPI38787.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain CAP PF00188.21 KPI38788.1 - 0.00011 22.7 10.4 0.0003 21.2 0.0 3.1 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Zn_clus PF00172.13 KPI38789.1 - 1e-08 34.8 7.2 1.7e-08 34.2 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPE65 PF03055.10 KPI38792.1 - 8.1e-120 400.6 0.0 9.3e-120 400.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF3455 PF11937.3 KPI38794.1 - 7.3e-37 127.0 0.2 4.4e-36 124.4 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.3 KPI38794.1 - 0.05 13.4 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) Acyl_transf_3 PF01757.17 KPI38797.1 - 8.7e-26 90.5 28.3 1.2e-25 90.1 19.6 1.1 1 0 0 1 1 1 1 Acyltransferase family Myb_DNA-binding PF00249.26 KPI38798.1 - 3.2e-12 46.3 0.0 7.8e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KPI38798.1 - 0.0013 18.7 0.1 0.23 11.6 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain adh_short PF00106.20 KPI38799.1 - 2.1e-23 83.0 0.0 4.9e-23 81.8 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI38799.1 - 4.1e-13 49.6 0.0 6e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI38799.1 - 7.2e-08 32.3 0.0 1.8e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KPI38799.1 - 0.0042 15.8 0.0 0.0069 15.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KPI38799.1 - 0.021 14.2 0.1 0.04 13.3 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Hist_deacetyl PF00850.14 KPI38801.1 - 6.9e-78 262.0 0.2 1.2e-77 261.3 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Cupin_8 PF13621.1 KPI38803.1 - 5.7e-44 150.5 0.0 7e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KPI38803.1 - 0.035 13.3 0.2 1 8.4 0.0 2.2 2 0 0 2 2 2 0 Cupin superfamily protein JmjC PF02373.17 KPI38803.1 - 0.068 13.4 0.1 2 8.6 0.0 2.3 2 0 0 2 2 2 0 JmjC domain, hydroxylase Amino_oxidase PF01593.19 KPI38805.1 - 1.2e-17 64.1 0.2 5.4e-17 61.9 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KPI38805.1 - 4.4e-14 52.2 0.2 1e-13 51.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI38805.1 - 1.1e-12 47.6 3.1 3.3e-11 42.7 2.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI38805.1 - 1.5e-08 33.9 3.5 3.9e-06 25.9 2.3 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 KPI38805.1 - 3.6e-08 33.7 0.1 0.00097 19.2 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI38805.1 - 1.8e-07 31.2 0.0 4.3e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI38805.1 - 1.9e-07 29.8 0.6 0.00027 19.5 0.7 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 KPI38805.1 - 4.4e-07 29.3 0.0 7.5e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KPI38805.1 - 1.2e-05 25.5 3.9 0.0024 18.2 1.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KPI38805.1 - 5.4e-05 22.0 3.5 0.057 12.0 0.7 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 KPI38805.1 - 8.7e-05 21.7 1.0 0.001 18.1 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KPI38805.1 - 0.00012 21.2 0.3 0.0002 20.5 0.2 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.1 KPI38805.1 - 0.0044 17.2 0.0 0.0089 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KPI38805.1 - 0.0049 15.8 2.3 0.037 12.9 0.5 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 KPI38805.1 - 0.0093 14.8 2.1 0.019 13.8 1.5 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KPI38805.1 - 0.011 15.5 3.9 0.043 13.5 0.2 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding ApbA PF02558.11 KPI38805.1 - 0.015 14.7 0.6 0.027 13.9 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 KPI38805.1 - 0.021 14.2 0.3 0.064 12.6 0.1 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 KPI38805.1 - 0.065 12.8 1.2 0.11 12.1 0.9 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 KPI38805.1 - 0.1 12.4 0.3 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.9 KPI38805.1 - 0.2 11.0 0.4 0.35 10.2 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fungal_trans PF04082.13 KPI38806.1 - 5.7e-14 51.6 0.4 1e-13 50.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI38806.1 - 9.6e-06 25.4 14.7 1.7e-05 24.6 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MBOAT_2 PF13813.1 KPI38807.1 - 1.2e-13 50.8 1.6 3.4e-13 49.4 1.1 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family CIA30 PF08547.7 KPI38808.1 - 6.8e-31 107.2 0.0 8.7e-31 106.9 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) S1-P1_nuclease PF02265.11 KPI38809.1 - 2.2e-61 207.7 0.0 2.6e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease Tyrosinase PF00264.15 KPI38810.1 - 1.1e-36 127.1 0.1 1.4e-36 126.7 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2408 PF10303.4 KPI38811.1 - 1.1e-48 164.8 3.2 6.1e-30 104.0 0.3 5.0 4 1 0 4 4 4 3 Protein of unknown function (DUF2408) Lant_dehyd_C PF04738.8 KPI38811.1 - 0.0046 15.2 0.1 0.0095 14.2 0.1 1.4 1 0 0 1 1 1 1 Lantibiotic dehydratase, C terminus Uds1 PF15456.1 KPI38811.1 - 0.074 13.0 0.3 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Up-regulated During Septation Tropomyosin_1 PF12718.2 KPI38811.1 - 0.091 12.6 1.4 0.37 10.6 0.3 2.1 2 0 0 2 2 2 0 Tropomyosin like NPV_P10 PF05531.7 KPI38811.1 - 0.26 11.5 3.0 6.3 7.1 0.1 3.5 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1772 PF08592.6 KPI38812.1 - 0.0024 17.6 0.1 0.0054 16.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF2721 PF11026.3 KPI38812.1 - 0.006 16.2 3.2 0.0099 15.5 2.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) Claudin_2 PF13903.1 KPI38812.1 - 0.0075 15.9 0.3 0.012 15.3 0.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Nucleoporin_C PF03177.9 KPI38813.1 - 5.1e-47 160.6 1.3 1.2e-46 159.4 0.9 1.6 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KPI38813.1 - 2e-36 125.6 0.0 3e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like LANC_like PF05147.8 KPI38814.1 - 4.6e-20 71.4 0.0 2.1e-18 66.0 0.0 2.3 2 1 0 2 2 2 2 Lanthionine synthetase C-like protein Gram_pos_anchor PF00746.16 KPI38816.1 - 0.063 13.1 1.1 0.063 13.1 0.8 2.4 2 0 0 2 2 2 0 Gram positive anchor Mucin PF01456.12 KPI38816.1 - 0.5 10.1 13.7 0.58 9.9 9.5 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Herpes_LMP1 PF05297.6 KPI38817.1 - 2.2 7.1 7.5 2.6 6.9 5.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Mito_carr PF00153.22 KPI38818.1 - 3e-40 135.8 6.0 7.9e-13 47.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein T2SM PF04612.7 KPI38818.1 - 0.12 12.1 0.3 0.32 10.7 0.1 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M 2-Hacid_dh_C PF02826.14 KPI38819.1 - 5.2e-33 113.6 0.0 8.6e-33 112.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KPI38819.1 - 0.0048 16.7 0.0 0.007 16.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Fungal_trans PF04082.13 KPI38820.1 - 4e-22 78.3 0.9 7.1e-22 77.5 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane_2 PF06472.10 KPI38821.1 - 2.3e-94 315.6 0.8 2.3e-94 315.6 0.6 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KPI38821.1 - 3.8e-15 56.3 0.0 3e-14 53.4 0.0 2.5 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.1 KPI38821.1 - 0.03 14.3 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.21 KPI38821.1 - 0.09 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF258 PF03193.11 KPI38821.1 - 0.17 11.0 0.0 0.46 9.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KPI38821.1 - 0.21 11.1 2.9 0.25 10.8 0.1 2.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain Zn_clus PF00172.13 KPI38822.1 - 0.00031 20.5 6.4 0.00056 19.7 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.23 KPI38823.1 - 9.4e-08 31.7 0.1 1.3e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KPI38823.1 - 7.9e-06 25.5 0.1 4.2e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 KPI38824.1 - 4.9e-19 68.5 0.0 6.7e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KPI38824.1 - 1.3e-07 31.3 2.7 8.8e-05 22.2 0.1 2.4 2 0 0 2 2 2 2 Peptidase dimerisation domain Zn_clus PF00172.13 KPI38825.1 - 1.2e-07 31.4 7.0 3.5e-07 30.0 4.9 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KPI38825.1 - 0.0028 16.3 0.2 0.0044 15.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Response_reg PF00072.19 KPI38826.1 - 4.9e-21 74.8 0.1 8.9e-16 57.8 0.0 2.3 1 1 1 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.21 KPI38826.1 - 1.6e-07 31.0 0.2 3e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Gln-synt_C PF00120.19 KPI38827.1 - 5.3e-39 133.9 0.0 8e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 KPI38827.1 - 9e-27 94.3 0.2 3e-26 92.6 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase PAS_4 PF08448.5 KPI38828.1 - 8.3e-15 54.7 0.0 4.1e-09 36.4 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 KPI38828.1 - 1.5e-12 47.8 0.0 4.5e-11 43.0 0.0 2.4 2 0 0 2 2 2 1 PAS domain HisKA PF00512.20 KPI38828.1 - 2.8e-09 36.8 0.3 8.4e-09 35.3 0.2 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 KPI38828.1 - 2.2e-06 27.4 0.0 1e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.6 KPI38828.1 - 9e-06 25.7 0.0 2.3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 KPI38828.1 - 9.5e-05 22.1 0.0 0.00054 19.7 0.0 2.3 2 0 0 2 2 2 1 PAS domain Rapsyn_N PF10579.4 KPI38828.1 - 0.086 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region MIF PF01187.13 KPI38829.1 - 3.3e-12 46.4 0.0 5.1e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Nic96 PF04097.9 KPI38831.1 - 7.8e-171 569.2 0.0 1.1e-170 568.8 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 KPI38831.1 - 2.8e-10 40.4 106.5 7.4e-09 35.8 30.3 4.6 3 1 1 4 4 4 2 Nucleoporin FG repeat region Glyco_hydro_3 PF00933.16 KPI38832.1 - 1e-46 159.2 0.0 4.4e-45 153.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KPI38832.1 - 5.7e-36 124.1 0.0 9.7e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KPI38832.1 - 2.1e-06 27.5 0.0 4.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3682 PF12446.3 KPI38832.1 - 0.31 11.3 2.0 0.74 10.1 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Amidase PF01425.16 KPI38833.1 - 1.5e-74 251.4 0.0 1.8e-74 251.1 0.0 1.1 1 0 0 1 1 1 1 Amidase PCI PF01399.22 KPI38834.1 - 9e-19 67.7 0.1 3.1e-18 66.0 0.0 1.9 1 0 0 1 1 1 1 PCI domain Fer2 PF00111.22 KPI38834.1 - 2.2e-07 30.5 0.5 6.1e-07 29.0 0.4 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PCI_Csn8 PF10075.4 KPI38834.1 - 0.037 13.7 0.0 0.13 11.9 0.0 1.9 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 SET PF00856.23 KPI38835.1 - 2.5e-21 76.6 0.3 2.5e-21 76.6 0.2 4.2 3 2 0 3 3 3 1 SET domain Sigma70_ner PF04546.8 KPI38835.1 - 0.033 13.7 15.1 0.34 10.4 5.7 2.8 2 0 0 2 2 2 0 Sigma-70, non-essential region SQS_PSY PF00494.14 KPI38836.1 - 1.2e-56 192.0 0.2 1.4e-56 191.7 0.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Peptidase_M24 PF00557.19 KPI38837.1 - 2.8e-45 154.4 0.0 3.5e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3074 PF11274.3 KPI38838.1 - 2.9e-58 196.5 3.3 1.5e-56 190.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) Suppressor_APC PF11414.3 KPI38838.1 - 4.4e-05 23.1 0.7 4.4e-05 23.1 0.5 2.4 2 1 0 2 2 2 1 Adenomatous polyposis coli tumour suppressor protein CAF-1_p150 PF11600.3 KPI38838.1 - 0.00047 19.6 35.8 0.00047 19.6 24.8 2.7 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal START PF01852.14 KPI38838.1 - 0.0014 17.9 0.0 0.031 13.5 0.0 2.2 2 0 0 2 2 2 1 START domain TPR_MLP1_2 PF07926.7 KPI38838.1 - 0.15 11.7 31.0 0.26 11.0 21.5 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF342 PF03961.8 KPI38838.1 - 0.16 10.3 15.7 0.23 9.8 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Thioredoxin_4 PF13462.1 KPI38838.1 - 1.9 8.4 7.9 4.4 7.2 5.5 1.6 1 0 0 1 1 1 0 Thioredoxin Ycf1 PF05758.7 KPI38838.1 - 9.8 3.7 17.9 14 3.2 12.4 1.1 1 0 0 1 1 1 0 Ycf1 LRR_4 PF12799.2 KPI38841.1 - 1.8e-11 43.3 3.3 2.4e-09 36.6 0.6 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KPI38841.1 - 5.3e-10 38.9 9.7 3.6e-06 26.6 1.3 2.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KPI38841.1 - 0.0005 19.7 5.6 0.16 12.1 0.3 4.0 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 KPI38841.1 - 0.067 13.4 8.2 0.64 10.4 0.1 4.2 5 0 0 5 5 5 0 Leucine rich repeat DUF3433 PF11915.3 KPI38842.1 - 3e-30 104.2 12.6 2.4e-26 91.6 1.5 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Pyr_redox_3 PF13738.1 KPI38844.1 - 7.8e-21 75.0 0.0 3.7e-20 72.8 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI38844.1 - 1e-07 31.8 0.3 3.5e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI38844.1 - 3.2e-07 29.6 0.0 5.4e-05 22.2 0.0 3.3 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KPI38844.1 - 2e-06 26.2 0.2 1.8e-05 23.1 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KPI38844.1 - 0.00028 20.8 0.0 0.058 13.2 0.0 2.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI38844.1 - 0.008 16.5 0.0 0.51 10.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KPI38844.1 - 0.05 13.7 0.0 5.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DOPA_dioxygen PF08883.6 KPI38845.1 - 1.1e-31 108.9 0.1 1.3e-31 108.7 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family CASP_C PF08172.7 KPI38846.1 - 1.2e-81 273.4 0.3 1.2e-81 273.4 0.2 3.6 3 2 0 3 3 3 1 CASP C terminal DUF904 PF06005.7 KPI38846.1 - 0.019 15.2 1.0 0.019 15.2 0.7 7.1 3 2 0 3 3 3 0 Protein of unknown function (DUF904) NAD_binding_1 PF00175.16 KPI38846.1 - 0.11 13.1 1.1 1.2 9.6 0.0 2.9 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4047 PF13256.1 KPI38846.1 - 0.14 12.0 0.1 0.14 12.0 0.1 4.0 4 2 0 4 4 4 0 Domain of unknown function (DUF4047) Tropomyosin_1 PF12718.2 KPI38846.1 - 0.4 10.5 71.2 0.37 10.6 11.0 5.6 3 1 2 5 5 5 0 Tropomyosin like UDG PF03167.14 KPI38847.1 - 4.7e-17 61.8 0.0 9.6e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF1977 PF09320.6 KPI38848.1 - 1.7e-25 89.3 0.1 3.1e-25 88.4 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 KPI38848.1 - 1.5e-22 79.1 0.2 1.5e-22 79.1 0.1 1.7 2 0 0 2 2 2 1 DnaJ domain ADP_ribosyl_GH PF03747.9 KPI38848.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase TOH_N PF12549.3 KPI38848.1 - 0.5 10.0 3.8 2 8.0 2.6 2.0 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal Coprogen_oxidas PF01218.13 KPI38851.1 - 1.2e-119 398.3 0.0 1.6e-119 397.8 0.0 1.2 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DIOX_N PF14226.1 KPI38852.1 - 6.2e-31 107.3 0.0 2.2e-30 105.5 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI38852.1 - 4.4e-14 52.5 0.0 7.7e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cellulase PF00150.13 KPI38853.1 - 7.6e-19 67.9 2.8 1e-18 67.5 0.1 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Y_phosphatase3C PF13348.1 KPI38853.1 - 0.12 12.4 0.1 2.5 8.2 0.0 2.8 3 0 0 3 3 3 0 Tyrosine phosphatase family C-terminal region PAN_4 PF14295.1 KPI38855.1 - 3.5 7.4 11.1 1.9 8.2 0.9 3.3 3 0 0 3 3 3 0 PAN domain ADH_zinc_N PF00107.21 KPI38856.1 - 7.1e-32 109.6 0.6 1.1e-31 109.0 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI38856.1 - 1.1e-17 65.0 0.1 2.7e-17 63.8 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI38856.1 - 1.3e-08 34.5 0.0 4.3e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KPI38856.1 - 5.8e-05 22.7 0.1 9.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 KPI38856.1 - 0.0015 18.5 0.1 0.0026 17.8 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KPI38856.1 - 0.0036 17.3 0.1 0.0079 16.1 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 KPI38856.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Tetraspannin PF00335.15 KPI38857.1 - 0.0034 16.6 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Tetraspanin family CcmD PF04995.9 KPI38857.1 - 0.031 14.0 1.4 0.65 9.7 0.3 2.6 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF4131 PF13567.1 KPI38857.1 - 2.6 7.4 6.0 0.65 9.3 1.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) ABC_tran_2 PF12848.2 KPI38858.1 - 0.081 12.7 1.3 0.12 12.2 0.9 1.3 1 0 0 1 1 1 0 ABC transporter Wbp11 PF09429.5 KPI38858.1 - 6.9 6.7 9.5 17 5.4 3.4 2.1 1 1 1 2 2 2 0 WW domain binding protein 11 GFO_IDH_MocA PF01408.17 KPI38859.1 - 2.7e-23 82.7 0.2 6.2e-23 81.5 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KPI38859.1 - 3.6e-06 26.7 0.0 7.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.12 KPI38859.1 - 0.011 16.1 0.1 0.029 14.7 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 KPI38859.1 - 0.029 14.6 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding COX16 PF14138.1 KPI38860.1 - 2e-26 91.9 0.0 2.6e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 NAD_binding_1 PF00175.16 KPI38861.1 - 1.1e-25 90.3 0.0 4.3e-25 88.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KPI38861.1 - 5.1e-13 48.9 0.0 1.1e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KPI38861.1 - 0.00017 21.5 0.0 0.0026 17.6 0.0 2.3 1 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KPI38861.1 - 0.16 11.9 0.0 0.62 10.0 0.0 1.9 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Cyt-b5 PF00173.23 KPI38862.1 - 3.6e-20 71.5 0.0 5.9e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain B12D PF06522.6 KPI38863.1 - 0.032 13.9 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Robl_LC7 PF03259.12 KPI38863.1 - 9.6 5.8 7.1 44 3.7 0.0 2.2 1 1 1 2 2 2 0 Roadblock/LC7 domain zf-C2H2_jaz PF12171.3 KPI38865.1 - 2e-07 30.9 4.7 2e-07 30.9 3.2 3.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KPI38865.1 - 0.0035 17.4 5.0 0.0068 16.4 3.5 1.5 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 KPI38865.1 - 0.15 12.4 0.1 0.15 12.4 0.1 2.6 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 KPI38865.1 - 1.4 9.3 4.8 4 7.9 1.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 KPI38865.1 - 1.8 8.8 6.8 5.6 7.3 2.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-U1 PF06220.7 KPI38865.1 - 8.1 6.1 6.7 1 8.9 1.3 2.0 2 0 0 2 2 2 0 U1 zinc finger BAG PF02179.11 KPI38866.1 - 2.8e-09 36.9 0.0 5.7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 KPI38866.1 - 9.3e-07 28.1 0.0 1.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KPI38866.1 - 0.021 14.4 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 KPI38866.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like VWA PF00092.23 KPI38867.1 - 3.9e-08 33.2 0.0 1e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KPI38867.1 - 5.6e-07 29.8 0.1 1.4e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KPI38867.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.1 KPI38867.1 - 0.06 13.0 0.0 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain FAD_binding_3 PF01494.14 KPI38868.1 - 9.5e-50 169.6 0.0 1.6e-49 168.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KPI38868.1 - 4.5e-06 25.7 0.4 0.0031 16.4 0.3 2.1 1 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KPI38868.1 - 2.7e-05 23.2 0.0 0.00022 20.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KPI38868.1 - 0.0001 20.9 0.1 0.0014 17.1 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KPI38868.1 - 0.00015 20.9 0.0 0.00027 20.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KPI38868.1 - 0.00026 20.9 0.1 0.00073 19.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI38868.1 - 0.00049 20.0 0.1 0.0016 18.3 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI38868.1 - 0.00065 19.8 0.1 0.0081 16.2 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI38868.1 - 0.0039 16.1 0.1 0.066 12.1 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.2 KPI38868.1 - 0.005 15.9 0.1 0.025 13.6 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KPI38868.1 - 0.0094 16.3 0.1 0.12 12.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KPI38868.1 - 0.021 13.4 0.2 3.4 6.1 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 KPI38868.1 - 0.038 12.8 0.1 0.055 12.3 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ThiF PF00899.16 KPI38868.1 - 0.14 11.9 0.2 0.56 10.0 0.1 2.0 2 0 0 2 2 2 0 ThiF family Clr5 PF14420.1 KPI38869.1 - 1.9e-15 56.4 0.8 3.8e-15 55.5 0.5 1.5 1 0 0 1 1 1 1 Clr5 domain DUF3712 PF12505.3 KPI38870.1 - 5e-11 42.7 0.2 2.1e-07 31.0 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3712) LEA_2 PF03168.8 KPI38870.1 - 3.7e-09 36.8 0.4 0.018 15.4 0.0 4.6 4 0 0 4 4 4 3 Late embryogenesis abundant protein CRC_subunit PF08624.5 KPI38871.1 - 8.5e-56 187.7 0.2 1.2e-55 187.1 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit AT_hook PF02178.14 KPI38871.1 - 1.2 9.0 8.4 4.1 7.4 5.8 2.0 1 0 0 1 1 1 0 AT hook motif Zn_clus PF00172.13 KPI38872.1 - 1.1e-06 28.4 10.5 2.1e-06 27.5 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BOP1NT PF08145.7 KPI38873.1 - 2.9e-104 348.4 7.5 5.1e-104 347.6 5.2 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain Rad52_Rad22 PF04098.10 KPI38873.1 - 3.5e-52 176.1 0.1 5.4e-52 175.6 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein WD40 PF00400.27 KPI38873.1 - 1.3e-25 88.3 4.1 2.9e-11 42.8 0.0 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Leo1 PF04004.8 KPI38874.1 - 4.3e-21 75.3 0.5 4.3e-21 75.3 0.3 1.9 2 0 0 2 2 2 1 Leo1-like protein FBPase PF00316.15 KPI38875.1 - 3.9e-45 154.0 0.1 1.7e-24 86.2 0.0 2.2 2 1 0 2 2 2 2 Fructose-1-6-bisphosphatase Bac_rhodopsin PF01036.13 KPI38877.1 - 2.7e-58 196.9 16.3 3.5e-58 196.5 11.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF21 PF01595.15 KPI38877.1 - 0.15 11.3 2.8 0.3 10.3 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF21 SirB PF04247.7 KPI38877.1 - 1.2 8.9 6.6 0.081 12.6 0.6 2.0 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB DUF4131 PF13567.1 KPI38877.1 - 1.9 7.8 12.8 0.21 10.9 2.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) YwiC PF14256.1 KPI38877.1 - 2.4 8.2 10.7 0.87 9.6 1.9 2.4 2 0 0 2 2 2 0 YwiC-like protein ADH_N PF08240.7 KPI38880.1 - 4.8e-23 80.9 0.1 1.1e-22 79.8 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ThiF PF00899.16 KPI38880.1 - 0.00013 21.8 0.8 0.00023 20.9 0.6 1.3 1 0 0 1 1 1 1 ThiF family Pyr_redox_3 PF13738.1 KPI38880.1 - 0.006 16.6 0.4 0.01 15.9 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KPI38880.1 - 0.01 15.9 0.4 0.043 13.9 0.2 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KPI38880.1 - 0.061 12.3 1.3 0.096 11.7 0.9 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 KPI38880.1 - 0.088 12.4 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KPI38880.1 - 0.1 12.0 0.1 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SnoaL_4 PF13577.1 KPI38881.1 - 5e-24 84.6 0.4 8.1e-24 83.9 0.2 1.3 1 0 0 1 1 1 1 SnoaL-like domain DivIC PF04977.10 KPI38881.1 - 0.041 13.3 0.3 0.093 12.2 0.2 1.6 1 0 0 1 1 1 0 Septum formation initiator FSA_C PF10479.4 KPI38882.1 - 0.023 12.7 0.1 0.033 12.2 0.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus zf-C3HC4_3 PF13920.1 KPI38884.1 - 1.7e-09 37.2 14.0 1.7e-09 37.2 9.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.24 KPI38884.1 - 0.00014 21.0 0.0 0.00031 19.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MORN PF02493.15 KPI38884.1 - 0.0014 18.2 16.2 0.031 13.9 2.1 4.0 4 0 0 4 4 4 2 MORN repeat USP7_ICP0_bdg PF12436.3 KPI38884.1 - 0.038 13.2 0.0 6.9 5.8 0.0 2.6 2 1 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 zf-C3HC4_2 PF13923.1 KPI38884.1 - 0.04 13.9 19.4 0.017 15.1 11.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) OKR_DC_1 PF01276.15 KPI38884.1 - 0.27 9.7 0.0 0.45 8.9 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DSPc PF00782.15 KPI38886.1 - 1.9e-08 33.9 0.1 3.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KPI38886.1 - 0.00074 18.9 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KPI38886.1 - 0.093 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Aconitase PF00330.15 KPI38887.1 - 2e-174 580.4 0.0 3.8e-174 579.5 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KPI38887.1 - 2.1e-48 163.7 0.0 3.4e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Zn_clus PF00172.13 KPI38888.1 - 0.095 12.6 8.4 0.2 11.5 5.8 1.6 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S7e PF01251.13 KPI38890.1 - 2.5e-80 268.4 0.1 3.1e-80 268.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Y_phosphatase PF00102.22 KPI38891.1 - 1.3e-39 135.9 0.3 7.6e-33 113.8 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 KPI38891.1 - 9.3e-11 42.0 0.1 4.6e-10 39.8 0.0 2.2 3 0 0 3 3 3 1 Rhodanese-like domain Aldedh PF00171.17 KPI38892.1 - 1.6e-147 491.5 0.2 1.9e-147 491.3 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.13 KPI38893.1 - 9.4e-07 27.9 0.0 1.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-DHHC PF01529.15 KPI38894.1 - 2.2e-30 105.3 5.7 2.2e-30 105.3 4.0 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase Pil1 PF13805.1 KPI38894.1 - 0.2 10.7 1.7 0.3 10.1 1.2 1.2 1 0 0 1 1 1 0 Eisosome component PIL1 DUF4131 PF13567.1 KPI38894.1 - 2 7.7 4.3 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF544 PF04424.8 KPI38896.1 - 1.9e-11 43.8 0.0 3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Amidase PF01425.16 KPI38897.1 - 4.4e-85 286.1 0.0 5e-85 285.9 0.0 1.0 1 0 0 1 1 1 1 Amidase bZIP_1 PF00170.16 KPI38898.1 - 0.00039 20.3 7.7 0.00039 20.3 5.4 2.1 2 0 0 2 2 2 1 bZIP transcription factor Cep57_CLD_2 PF14197.1 KPI38898.1 - 0.022 14.7 2.4 0.074 12.9 0.2 2.7 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Phlebovirus_NSM PF07246.6 KPI38898.1 - 0.05 12.7 0.5 0.073 12.2 0.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4439 PF14530.1 KPI38898.1 - 0.053 13.9 0.2 21 5.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4439) DUF2046 PF09755.4 KPI38898.1 - 0.079 11.8 3.1 1.5 7.5 1.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) bZIP_Maf PF03131.12 KPI38898.1 - 0.31 11.3 8.2 0.45 10.8 3.4 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor adh_short PF00106.20 KPI38899.1 - 5.8e-17 62.0 0.0 7.7e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI38899.1 - 5e-07 29.5 0.0 8.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 KR domain WD40 PF00400.27 KPI38900.1 - 5.4e-59 194.1 14.7 1.2e-09 37.7 0.0 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KPI38900.1 - 0.00015 20.6 2.7 0.12 11.0 0.2 2.4 1 1 1 2 2 2 2 Nup133 N terminal like Gmad1 PF10647.4 KPI38900.1 - 0.0015 17.9 0.6 0.044 13.1 0.1 2.5 2 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain BTB PF00651.26 KPI38901.1 - 2.1e-09 37.3 0.1 0.0015 18.4 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain Sugar_tr PF00083.19 KPI38902.1 - 7.4e-99 331.3 20.6 9.1e-99 331.0 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1768 PF08719.6 KPI38902.1 - 2.9e-42 144.0 0.0 4.6e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) MFS_1 PF07690.11 KPI38902.1 - 2.7e-16 59.2 24.2 2.7e-16 59.2 16.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Xan_ur_permease PF00860.15 KPI38903.1 - 0.11 10.9 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Permease family TRIQK PF15168.1 KPI38903.1 - 0.11 12.4 0.1 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family NmrA PF05368.8 KPI38904.1 - 7.7e-29 100.5 0.0 9.7e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI38904.1 - 3.6e-14 53.1 0.0 4.9e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI38904.1 - 1.1e-07 31.4 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KPI38904.1 - 0.0014 18.6 0.1 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI38904.1 - 0.0015 18.2 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KPI38904.1 - 0.004 15.9 0.0 0.0062 15.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KPI38904.1 - 0.0041 17.4 0.0 0.014 15.7 0.0 1.8 1 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KPI38904.1 - 0.047 12.5 0.0 0.094 11.5 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Septin PF00735.13 KPI38905.1 - 6.2e-35 120.5 0.0 5.7e-12 45.2 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 KPI38905.1 - 0.043 13.2 0.0 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 KPI38905.1 - 0.13 12.0 0.0 0.59 9.9 0.0 2.0 2 0 0 2 2 2 0 Dynamin family Thioredoxin PF00085.15 KPI38906.1 - 2.3e-44 149.3 0.1 2.1e-23 81.9 0.0 4.2 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KPI38906.1 - 7.1e-12 45.5 0.0 0.025 14.4 0.0 4.3 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KPI38906.1 - 1.1e-05 25.5 2.8 0.065 13.4 0.0 4.5 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KPI38906.1 - 0.00077 19.5 0.2 1.4 9.0 0.0 3.7 3 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.1 KPI38906.1 - 0.005 16.6 0.0 0.28 11.0 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_7 PF13899.1 KPI38906.1 - 0.038 14.0 1.3 1.6 8.7 0.0 3.4 3 0 0 3 3 3 0 Thioredoxin-like HyaE PF07449.6 KPI38906.1 - 0.07 13.0 0.0 6.3 6.7 0.0 2.8 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.1 KPI38906.1 - 0.69 9.4 5.5 2.1 7.9 0.1 2.9 3 0 0 3 3 3 0 Thioredoxin HSP20 PF00011.16 KPI38907.1 - 2.4e-10 40.1 0.7 3.9e-10 39.4 0.1 1.7 2 0 0 2 2 2 1 Hsp20/alpha crystallin family Na_H_Exchanger PF00999.16 KPI38908.1 - 4.1e-63 213.1 50.6 6.2e-63 212.5 35.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family AFOR_C PF01314.13 KPI38908.1 - 0.13 10.9 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 TPR_11 PF13414.1 KPI38909.1 - 7.8e-38 127.9 23.8 1.6e-14 53.2 0.2 5.9 3 3 3 6 6 6 5 TPR repeat TPR_1 PF00515.23 KPI38909.1 - 2.2e-27 93.5 17.4 6.7e-08 31.8 0.3 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 KPI38909.1 - 2.5e-26 89.4 19.9 1.6e-05 24.4 0.2 8.1 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_19 PF14559.1 KPI38909.1 - 5.6e-21 74.6 26.7 0.00041 20.6 0.2 6.6 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 KPI38909.1 - 2.1e-20 72.8 20.0 4e-05 24.1 1.9 6.7 4 2 3 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.26 KPI38909.1 - 8.4e-19 67.0 2.3 8.4e-19 67.0 1.6 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_14 PF13428.1 KPI38909.1 - 1.5e-16 59.4 15.3 0.017 15.7 0.0 8.1 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 KPI38909.1 - 3.9e-13 48.4 16.2 0.0067 16.5 0.4 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 KPI38909.1 - 2.2e-12 45.7 11.7 0.06 13.1 0.2 6.8 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KPI38909.1 - 7.3e-11 41.8 19.9 0.00023 21.0 1.9 5.6 2 2 3 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 KPI38909.1 - 1.3e-10 40.2 14.5 0.041 13.6 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 KPI38909.1 - 2.4e-09 37.1 8.9 6.8e-05 22.9 1.7 4.0 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 KPI38909.1 - 1.5e-08 34.3 6.1 0.0098 15.7 0.1 5.3 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KPI38909.1 - 3.2e-07 30.3 15.2 1.8 9.1 0.1 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat BTAD PF03704.12 KPI38909.1 - 4.1e-06 27.1 5.5 0.15 12.3 0.3 4.0 3 2 1 4 4 4 2 Bacterial transcriptional activator domain TOM20_plant PF06552.7 KPI38909.1 - 2.6e-05 23.8 0.8 0.0018 17.8 0.0 2.7 2 0 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_9 PF13371.1 KPI38909.1 - 0.00012 21.8 12.0 0.082 12.7 0.1 5.2 3 2 1 5 5 5 2 Tetratricopeptide repeat ChAPs PF09295.5 KPI38909.1 - 0.003 16.3 0.8 0.015 14.1 0.2 2.0 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) RPN7 PF10602.4 KPI38909.1 - 0.017 14.5 0.5 0.43 9.9 0.0 2.8 1 1 1 2 2 2 0 26S proteasome subunit RPN7 ABC_trans_N PF14510.1 KPI38909.1 - 0.088 12.9 0.4 3.3 7.8 0.1 3.0 2 0 0 2 2 2 0 ABC-transporter extracellular N-terminal TPR_20 PF14561.1 KPI38909.1 - 0.11 12.6 15.2 0.11 12.5 0.6 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 KPI38909.1 - 0.11 12.4 3.1 22 4.9 0.3 4.0 2 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.1 KPI38909.1 - 0.11 12.7 8.8 13 6.0 0.3 4.3 2 2 2 4 4 4 0 Alkyl sulfatase dimerisation RPT PF13446.1 KPI38909.1 - 0.17 11.2 0.0 0.17 11.2 0.0 3.2 4 0 0 4 4 4 0 A repeated domain in UCH-protein TPR_10 PF13374.1 KPI38909.1 - 0.52 10.3 17.3 6.2 6.9 0.0 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat ADH_zinc_N PF00107.21 KPI38910.1 - 6.5e-25 87.1 1.1 8e-25 86.8 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI38910.1 - 8.9e-23 80.1 1.5 1.4e-22 79.5 0.3 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KPI38910.1 - 4.4e-06 27.6 0.1 8.1e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KPI38910.1 - 0.00031 21.3 0.1 0.00061 20.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 KPI38910.1 - 0.0008 18.8 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 KPI38910.1 - 0.0013 18.3 0.2 0.0027 17.3 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DapB_N PF01113.15 KPI38910.1 - 0.011 15.6 0.3 0.022 14.6 0.2 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PrmA PF06325.8 KPI38910.1 - 0.023 13.8 0.1 0.042 12.9 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 2-Hacid_dh_C PF02826.14 KPI38910.1 - 0.039 13.0 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 KPI38910.1 - 0.092 11.2 0.2 0.12 10.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Methyltransf_11 PF08241.7 KPI38910.1 - 0.1 13.1 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KPI38911.1 - 9e-09 35.2 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI38911.1 - 3.3e-08 33.8 0.0 7.1e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI38911.1 - 0.00014 21.5 0.0 0.0022 17.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI38911.1 - 0.00035 20.9 0.0 0.00088 19.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DUF3425 PF11905.3 KPI38913.1 - 4.1e-15 55.8 4.2 1.3e-14 54.2 2.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Suppressor_APC PF11414.3 KPI38913.1 - 0.046 13.5 1.8 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein DASH_Dad2 PF08654.5 KPI38913.1 - 0.19 11.7 1.3 3.1 7.8 0.0 2.9 3 1 0 3 3 3 0 DASH complex subunit Dad2 Snf7 PF03357.16 KPI38913.1 - 1.6 8.0 5.4 7.8 5.8 0.6 2.3 2 0 0 2 2 2 0 Snf7 Dus PF01207.12 KPI38915.1 - 5.4e-54 183.1 0.0 1.4e-53 181.8 0.0 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DUF504 PF04457.7 KPI38915.1 - 9.7e-07 28.8 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF504) DUF2856 PF11043.3 KPI38915.1 - 0.011 15.8 0.1 0.036 14.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) Mnd1 PF03962.10 KPI38915.1 - 9.7 5.7 12.3 2.7 7.5 5.0 2.3 2 0 0 2 2 2 0 Mnd1 family Asp_Glu_race PF01177.17 KPI38916.1 - 2.4e-29 102.8 0.0 2.7e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DAO PF01266.19 KPI38917.1 - 1.4e-48 165.5 0.0 2.1e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI38917.1 - 1.2e-08 34.2 0.4 2.6e-08 33.1 0.3 1.5 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KPI38917.1 - 1.4e-05 24.3 0.4 2.8e-05 23.3 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI38917.1 - 0.0012 18.7 0.1 0.0061 16.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI38917.1 - 0.0056 16.6 0.2 0.023 14.7 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KPI38917.1 - 0.0077 15.8 0.2 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KPI38917.1 - 0.016 14.0 0.1 0.14 10.9 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 KPI38917.1 - 0.025 14.9 0.2 0.24 11.8 0.1 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 KPI38917.1 - 0.051 13.5 1.2 0.32 10.9 0.1 2.4 2 0 0 2 2 2 0 NADH(P)-binding HI0933_like PF03486.9 KPI38917.1 - 0.083 11.3 0.2 0.14 10.6 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Velvet PF11754.3 KPI38918.1 - 9.9e-13 48.1 0.0 9.9e-13 48.1 0.0 2.6 3 0 0 3 3 3 1 Velvet factor Reo_sigmaC PF04582.7 KPI38918.1 - 4.4e-06 26.1 18.3 0.0023 17.1 0.9 3.0 2 1 1 3 3 3 3 Reovirus sigma C capsid protein GRAB PF10375.4 KPI38918.1 - 0.00031 20.2 0.0 0.00056 19.4 0.0 1.4 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Filament PF00038.16 KPI38918.1 - 0.0083 15.6 49.5 0.16 11.3 20.8 2.4 1 1 1 2 2 2 1 Intermediate filament protein Atg14 PF10186.4 KPI38918.1 - 0.027 13.4 41.5 0.12 11.3 5.8 3.3 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 HALZ PF02183.13 KPI38918.1 - 0.029 14.0 0.3 0.029 14.0 0.2 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 KPI38918.1 - 0.098 12.4 24.7 0.1 12.3 4.9 3.5 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus WEMBL PF05701.6 KPI38918.1 - 0.16 10.4 50.4 0.52 8.7 34.4 1.8 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF3584 PF12128.3 KPI38918.1 - 0.24 8.6 47.4 1 6.6 32.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 KPI38918.1 - 0.65 9.5 54.7 1.9 8.0 9.1 3.7 1 1 2 3 3 3 0 IncA protein MAD PF05557.8 KPI38918.1 - 1.2 7.1 51.0 0.96 7.4 12.9 3.2 1 1 2 3 3 3 0 Mitotic checkpoint protein CENP-F_leu_zip PF10473.4 KPI38918.1 - 1.5 8.6 56.1 0.6 9.9 9.5 4.2 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4239 PF14023.1 KPI38918.1 - 3.3 7.0 13.3 0.58 9.4 1.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4239) Spc7 PF08317.6 KPI38918.1 - 5.2 5.6 43.9 3.7 6.1 9.5 3.0 1 1 0 2 2 2 0 Spc7 kinetochore protein DASH_Dam1 PF08653.5 KPI38918.1 - 5.5 6.8 5.1 35 4.2 0.2 3.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 FliJ PF02050.11 KPI38918.1 - 5.8 6.9 43.1 0.054 13.5 14.1 4.2 1 1 3 4 4 4 0 Flagellar FliJ protein Fib_alpha PF08702.5 KPI38918.1 - 8.2 6.5 29.4 9.2 6.3 3.9 3.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Transposase_22 PF02994.9 KPI38918.1 - 9.3 4.6 33.5 0.1 11.0 2.6 2.6 1 1 2 3 3 3 0 L1 transposable element Exo_endo_phos PF03372.18 KPI38919.1 - 2.4e-10 40.7 2.8 1.3e-09 38.4 1.9 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KPI38919.1 - 7.2e-07 28.8 0.9 1e-06 28.3 0.6 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase CN_hydrolase PF00795.17 KPI38920.1 - 0.00023 20.5 0.0 0.00046 19.5 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase KH_1 PF00013.24 KPI38920.1 - 0.03 13.9 0.1 0.066 12.8 0.1 1.6 1 0 0 1 1 1 0 KH domain SLS PF14611.1 KPI38920.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator DUF2348 PF09807.4 KPI38921.1 - 1.8e-11 43.6 0.0 2.3e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 KPI38921.1 - 0.0041 16.2 0.1 0.006 15.7 0.0 1.1 1 0 0 1 1 1 1 KaiC NACHT PF05729.7 KPI38921.1 - 0.065 12.8 1.1 0.32 10.6 0.2 2.1 1 1 1 2 2 2 0 NACHT domain DUF3072 PF11272.3 KPI38921.1 - 0.14 11.7 0.2 0.37 10.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) Fungal_trans PF04082.13 KPI38922.1 - 7.6e-12 44.6 0.7 1.7e-11 43.4 0.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain PS_Dcarbxylase PF02666.10 KPI38923.1 - 1.4e-79 266.1 0.0 3.5e-78 261.5 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase HlyD_2 PF12700.2 KPI38923.1 - 0.0036 16.5 0.1 0.0053 15.9 0.1 1.2 1 0 0 1 1 1 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 KPI38923.1 - 0.0061 16.1 1.1 0.014 15.0 0.7 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like Biotin_lipoyl PF00364.17 KPI38923.1 - 0.085 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme CIAPIN1 PF05093.8 KPI38924.1 - 5.2e-35 119.5 4.1 9.7e-35 118.6 2.9 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Sad1_UNC PF07738.8 KPI38925.1 - 4e-08 33.1 0.0 2.9e-07 30.3 0.0 2.2 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal IncA PF04156.9 KPI38925.1 - 0.015 14.8 4.9 0.068 12.7 0.1 2.7 2 0 0 2 2 2 0 IncA protein Phage_H_T_join PF05521.6 KPI38925.1 - 0.073 13.3 1.0 0.38 11.0 0.0 2.4 2 0 0 2 2 2 0 Phage head-tail joining protein CDC45 PF02724.9 KPI38925.1 - 0.37 8.7 6.9 0.51 8.2 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.6 KPI38925.1 - 0.72 9.7 15.2 1.2 8.9 10.6 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop14 PF04147.7 KPI38925.1 - 0.86 7.4 11.2 1.3 6.8 7.7 1.2 1 0 0 1 1 1 0 Nop14-like family MoCF_biosynth PF00994.19 KPI38927.1 - 7.8e-25 86.9 0.0 4e-24 84.6 0.0 1.9 2 0 0 2 2 2 1 Probable molybdopterin binding domain CENP-S PF15630.1 KPI38928.1 - 3.2e-24 84.8 0.0 5.1e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 KPI38928.1 - 0.00045 19.6 0.1 0.00045 19.6 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KPI38928.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DnaJ PF00226.26 KPI38929.1 - 1.1e-14 53.9 1.3 1.1e-14 53.9 0.9 2.2 2 0 0 2 2 2 1 DnaJ domain Podoplanin PF05808.6 KPI38930.1 - 4.7e-06 26.2 0.0 6.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Podoplanin GPI-anchored PF10342.4 KPI38930.1 - 0.00017 22.0 1.4 0.00064 20.1 1.0 1.9 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family VSP PF03302.8 KPI38930.1 - 0.0002 20.1 0.2 0.00027 19.6 0.1 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein TMEM154 PF15102.1 KPI38930.1 - 0.003 17.2 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family MtrF PF09472.5 KPI38930.1 - 0.0039 16.3 4.1 0.016 14.4 2.5 2.0 2 0 0 2 2 2 1 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SKG6 PF08693.5 KPI38930.1 - 0.0044 16.3 0.3 0.0095 15.2 0.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Amnionless PF14828.1 KPI38930.1 - 0.029 12.8 0.0 0.04 12.4 0.0 1.2 1 0 0 1 1 1 0 Amnionless PepSY_TM_3 PF13706.1 KPI38930.1 - 0.032 13.6 0.7 0.032 13.6 0.5 1.8 2 0 0 2 2 2 0 PepSY-associated TM helix DUF1183 PF06682.7 KPI38930.1 - 0.042 13.4 0.3 0.051 13.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) EphA2_TM PF14575.1 KPI38930.1 - 0.078 13.3 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 KPI38930.1 - 0.085 11.1 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E FTR1 PF03239.9 KPI38930.1 - 0.092 11.6 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family BatD PF13584.1 KPI38930.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance Syndecan PF01034.15 KPI38930.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain DUF2668 PF10873.3 KPI38930.1 - 0.15 12.2 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) Gram_pos_anchor PF00746.16 KPI38930.1 - 2 8.2 4.1 6 6.8 2.9 1.9 1 0 0 1 1 1 0 Gram positive anchor Oligomerisation PF02410.10 KPI38931.1 - 0.00022 21.1 0.1 0.58 10.2 0.0 3.1 3 1 0 3 3 3 2 Oligomerisation domain ABC_tran PF00005.22 KPI38933.1 - 5.4e-40 136.8 0.1 5.2e-19 68.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KPI38933.1 - 5.1e-21 75.0 37.9 3.9e-11 42.5 12.8 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KPI38933.1 - 5.9e-15 56.0 0.0 6.5e-05 23.0 0.0 4.3 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 KPI38933.1 - 2.1e-07 30.3 0.0 0.022 14.0 0.0 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KPI38933.1 - 1.6e-06 27.5 1.4 0.001 18.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KPI38933.1 - 7.9e-06 26.3 0.0 0.047 14.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KPI38933.1 - 0.00028 21.0 0.2 0.093 12.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 KPI38933.1 - 0.0014 17.8 0.1 0.09 11.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KPI38933.1 - 0.0035 17.2 0.2 4.5 7.2 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 KPI38933.1 - 0.014 14.9 0.9 2.2 7.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KPI38933.1 - 0.037 14.2 0.3 6.9 6.8 0.0 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KPI38933.1 - 0.056 13.2 1.0 6 6.6 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain AIG1 PF04548.11 KPI38933.1 - 0.063 12.3 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 AIG1 family MukB PF04310.7 KPI38933.1 - 0.075 12.3 1.1 0.44 9.8 0.1 2.5 2 0 0 2 2 2 0 MukB N-terminal SRP54 PF00448.17 KPI38933.1 - 0.075 12.4 3.3 3.7 6.9 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 KPI38933.1 - 0.16 11.0 1.1 9.7 5.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_13 PF13166.1 KPI38933.1 - 0.16 10.3 0.1 3.9 5.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KPI38933.1 - 0.23 11.3 0.5 10 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KPI38933.1 - 0.26 11.2 0.5 0.84 9.6 0.1 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.12 KPI38933.1 - 0.3 10.8 0.7 1.7 8.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 NB-ARC PF00931.17 KPI38933.1 - 0.4 9.4 0.5 0.71 8.6 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_10 PF12846.2 KPI38933.1 - 0.83 9.0 1.9 2.1 7.7 0.1 2.2 2 0 0 2 2 2 0 AAA-like domain RecO_N PF11967.3 KPI38934.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Recombination protein O N terminal peroxidase PF00141.18 KPI38935.1 - 2.5e-22 79.4 0.0 3.9e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Glyoxalase_2 PF12681.2 KPI38936.1 - 1.5e-14 54.4 0.0 1.9e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KPI38936.1 - 9.4e-08 32.0 0.0 1.2e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily LNS2 PF08235.8 KPI38937.1 - 2.9e-72 241.3 0.0 4.6e-72 240.7 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KPI38937.1 - 8e-40 134.9 0.0 1.6e-39 133.9 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 KPI38937.1 - 0.014 14.7 0.0 0.075 12.3 0.0 2.1 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) PMT PF02366.13 KPI38937.1 - 0.029 13.7 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase SURF2 PF05477.6 KPI38937.1 - 2.4 7.2 4.1 4.2 6.4 2.8 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) HemY_N PF07219.8 KPI38939.1 - 0.85 9.2 3.7 1.9 8.0 2.5 1.6 1 0 0 1 1 1 0 HemY protein N-terminus DUF3043 PF11241.3 KPI38939.1 - 1.4 8.5 12.6 2.3 7.7 8.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) ATP_bind_1 PF03029.12 KPI38940.1 - 1.6e-72 243.9 0.0 1.9e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 KPI38940.1 - 0.0062 15.3 0.4 0.012 14.3 0.0 1.6 2 0 0 2 2 2 1 ArgK protein Taxilin PF09728.4 KPI38940.1 - 0.0098 15.0 1.2 0.2 10.7 0.0 2.1 2 0 0 2 2 2 1 Myosin-like coiled-coil protein CbiA PF01656.18 KPI38940.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 KPI38940.1 - 0.013 14.6 0.0 0.035 13.1 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 KPI38940.1 - 0.028 15.2 2.8 0.057 14.2 0.5 2.4 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KPI38940.1 - 0.097 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 KPI38940.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribonucleas_3_3 PF14622.1 KPI38941.1 - 9.5e-09 35.2 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KPI38941.1 - 0.00021 21.7 0.0 0.00075 19.9 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Oxidored_molyb PF00174.14 KPI38942.1 - 5.7e-46 156.0 0.0 1.3e-45 154.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KPI38942.1 - 9.7e-25 86.7 4.2 2.2e-24 85.5 2.9 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain I_LWEQ PF01608.12 KPI38942.1 - 0.039 13.8 0.0 2.1 8.3 0.0 2.8 3 0 0 3 3 3 0 I/LWEQ domain SLBB PF10531.4 KPI38942.1 - 0.056 13.3 0.0 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 SLBB domain ECH PF00378.15 KPI38943.1 - 1.9e-29 102.5 0.1 4.1e-29 101.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF3337 PF11816.3 KPI38944.1 - 4.7e-84 282.6 0.6 5.5e-79 265.9 0.1 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3337) WD40 PF00400.27 KPI38944.1 - 1.9e-18 65.5 8.3 2.9e-06 26.9 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat PAT1 PF09770.4 KPI38945.1 - 5.5e-247 822.0 17.2 6.4e-247 821.8 11.9 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 CPSF_A PF03178.10 KPI38947.1 - 0.069 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 CPSF A subunit region TFIID-31kDa PF02291.10 KPI38948.1 - 5.5e-24 84.4 0.0 2.5e-13 49.9 0.0 2.3 1 1 1 2 2 2 2 Transcription initiation factor IID, 31kD subunit TP2 PF01254.13 KPI38948.1 - 0.96 9.7 6.4 1.2 9.5 4.1 1.4 1 1 0 1 1 1 0 Nuclear transition protein 2 Lipase_3 PF01764.20 KPI38949.1 - 3.1e-25 88.4 0.1 3.2e-23 81.8 0.0 2.2 1 1 1 2 2 2 2 Lipase (class 3) DUF2974 PF11187.3 KPI38949.1 - 0.00036 19.9 0.0 0.00046 19.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 KPI38949.1 - 0.00041 20.1 0.1 0.00048 19.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KPI38949.1 - 0.0091 15.7 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.2 KPI38949.1 - 0.024 14.5 0.1 0.025 14.4 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 KPI38949.1 - 0.041 13.4 0.1 0.067 12.7 0.0 1.3 1 1 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.9 KPI38949.1 - 0.042 13.1 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Rib_5-P_isom_A PF06026.9 KPI38950.1 - 7.1e-35 119.8 0.0 1.3e-31 109.2 0.0 2.1 1 1 1 2 2 2 2 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 KPI38950.1 - 0.0058 16.2 0.0 2.2 7.9 0.0 2.2 2 0 0 2 2 2 2 DeoR C terminal sensor domain Abhydrolase_6 PF12697.2 KPI38951.1 - 5.2e-23 82.1 0.1 6.5e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI38951.1 - 4e-08 33.1 0.0 6.7e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family RRM_1 PF00076.17 KPI38952.1 - 5.8e-42 141.1 0.0 5.5e-16 57.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI38952.1 - 9.5e-25 86.3 0.0 1.3e-08 34.6 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI38952.1 - 5.5e-19 67.7 0.0 1.7e-07 30.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NUDIX PF00293.23 KPI38952.1 - 7.8e-16 57.9 0.1 1.5e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_4 PF13420.1 KPI38952.1 - 5.3e-09 36.1 0.4 0.098 12.6 0.1 3.4 3 0 0 3 3 3 3 Acetyltransferase (GNAT) domain RRM_3 PF08777.6 KPI38952.1 - 0.00014 21.6 0.4 0.00066 19.4 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 KPI38952.1 - 0.011 15.5 0.0 0.054 13.2 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Acetyltransf_1 PF00583.19 KPI38952.1 - 0.059 13.4 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family eIF3g PF12353.3 KPI38952.1 - 0.17 11.7 2.3 0.6 10.0 0.7 2.5 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G DUF2454 PF10521.4 KPI38954.1 - 4e-47 160.5 1.7 5.6e-47 160.0 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) WSC PF01822.14 KPI38955.1 - 1.7e-09 37.4 6.7 1.7e-09 37.4 4.7 2.2 2 0 0 2 2 2 1 WSC domain EphA2_TM PF14575.1 KPI38955.1 - 0.0051 17.1 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF2668 PF10873.3 KPI38955.1 - 0.026 14.6 0.0 0.026 14.6 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2668) Syndecan PF01034.15 KPI38955.1 - 0.099 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.1 KPI38955.1 - 0.23 11.1 8.0 0.12 12.0 0.2 3.1 1 1 0 2 2 2 0 TMEM154 protein family FAM163 PF15069.1 KPI38955.1 - 0.39 11.2 6.9 0.056 14.0 0.4 2.8 2 2 0 2 2 2 0 FAM163 family Cmc1 PF08583.5 KPI38956.1 - 2.3e-12 46.4 14.0 1.3e-11 44.1 9.7 2.2 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 KPI38956.1 - 0.011 15.1 0.8 0.022 14.1 0.6 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Med2 PF11214.3 KPI38956.1 - 0.25 11.3 2.9 0.45 10.5 2.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 DFF40 PF09230.5 KPI38956.1 - 1.4 8.2 5.8 1.7 7.9 3.6 1.4 1 1 0 1 1 1 0 DNA fragmentation factor 40 kDa p450 PF00067.17 KPI38957.1 - 2.5e-37 128.5 0.0 3e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Arf PF00025.16 KPI38958.1 - 2.4e-62 209.2 0.3 2.7e-62 209.1 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KPI38958.1 - 8.6e-12 44.4 6.1 1.8e-06 26.9 1.7 2.9 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KPI38958.1 - 5.2e-10 38.8 0.0 6.2e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KPI38958.1 - 4.3e-09 36.3 0.0 6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KPI38958.1 - 2e-08 33.7 0.0 2.3e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KPI38958.1 - 1e-06 28.1 0.0 1.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KPI38958.1 - 2.4e-06 28.0 0.0 3.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KPI38958.1 - 8.1e-06 25.3 0.0 0.0011 18.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 KPI38958.1 - 0.037 14.8 0.0 0.047 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KPI38958.1 - 0.038 13.4 0.0 4.2 6.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF1547 PF07577.6 KPI38958.1 - 0.061 13.0 0.0 1 9.0 0.0 2.3 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1547) PPK2 PF03976.9 KPI38958.1 - 0.065 12.5 0.0 4.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) PduV-EutP PF10662.4 KPI38958.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.13 KPI38958.1 - 0.12 11.4 0.1 0.26 10.3 0.0 1.6 1 1 0 2 2 2 0 6-phosphofructo-2-kinase FMN_red PF03358.10 KPI38959.1 - 1.7e-28 99.0 0.0 2.2e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KPI38959.1 - 3.6e-06 26.6 0.0 4.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Endosulfine PF04667.12 KPI38960.1 - 2.8e-21 75.2 0.1 4.4e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DNA_pol_A PF00476.15 KPI38961.1 - 2.7e-102 342.2 0.0 3.4e-102 341.9 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A DUF1454 PF07305.7 KPI38961.1 - 0.016 14.3 0.1 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) MFS_1 PF07690.11 KPI38962.1 - 9.9e-34 116.5 65.7 2.6e-31 108.6 43.0 4.0 2 1 0 2 2 2 2 Major Facilitator Superfamily ICE2 PF08426.5 KPI38964.1 - 2.2e-123 411.9 7.1 2.5e-123 411.7 4.9 1.0 1 0 0 1 1 1 1 ICE2 DUF1361 PF07099.6 KPI38964.1 - 0.0037 17.0 3.0 3.1 7.5 0.0 3.5 2 1 1 3 3 3 3 Protein of unknown function (DUF1361) PolyA_pol_RNAbd PF12627.2 KPI38965.1 - 7.8e-06 25.3 0.0 2.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DUF957 PF06117.6 KPI38965.1 - 0.1 12.1 0.1 0.45 10.1 0.0 2.0 2 1 0 2 2 2 0 Enterobacterial protein of unknown function (DUF957) PolyA_pol PF01743.15 KPI38966.1 - 4.7e-19 68.8 1.2 3e-18 66.2 0.8 1.9 1 1 0 1 1 1 1 Poly A polymerase head domain DCP2 PF05026.8 KPI38967.1 - 7.4e-32 109.0 2.2 1.4e-31 108.2 1.6 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 KPI38967.1 - 5.2e-21 74.7 0.0 9.7e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SPO11_like PF03533.9 KPI38967.1 - 9.4e-05 22.2 1.1 0.11 12.3 0.1 3.1 2 0 0 2 2 2 2 SPO11 homologue Nop14 PF04147.7 KPI38968.1 - 0.023 12.6 0.5 0.032 12.1 0.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1401 PF07180.6 KPI38968.1 - 0.052 13.2 0.2 0.14 11.9 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1401) DUF1764 PF08576.5 KPI38968.1 - 0.081 13.7 1.9 0.13 13.0 1.3 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) FAD_binding_4 PF01565.18 KPI38969.1 - 9.8e-11 41.2 0.0 1.3e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 KPI38969.1 - 5.1e-06 26.2 1.5 7.4e-06 25.7 0.2 1.8 2 0 0 2 2 2 1 Berberine and berberine like Fungal_trans PF04082.13 KPI38970.1 - 3.4e-20 72.0 0.1 4.5e-20 71.6 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_3 PF00202.16 KPI38972.1 - 5.5e-82 275.3 0.5 6.6e-82 275.0 0.3 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Syja_N PF02383.13 KPI38974.1 - 1.7e-90 303.0 0.1 3e-90 302.2 0.1 1.4 1 0 0 1 1 1 1 SacI homology domain RNase_P_Rpp14 PF01900.14 KPI38975.1 - 1e-32 112.1 0.0 1.3e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Aldo_ket_red PF00248.16 KPI38976.1 - 3.7e-63 213.0 0.0 4.5e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SNF2_N PF00176.18 KPI38979.1 - 1e-71 241.2 0.0 1.4e-71 240.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KPI38979.1 - 1e-21 76.8 0.0 2.5e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KPI38979.1 - 4.6e-12 45.6 0.0 8.9e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KPI38979.1 - 5.2e-07 29.5 9.0 9.5e-07 28.7 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KPI38979.1 - 1.6e-05 24.4 5.4 2.9e-05 23.6 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KPI38979.1 - 9.5e-05 22.1 7.0 0.00018 21.2 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KPI38979.1 - 0.00015 21.3 9.5 0.00027 20.5 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI38979.1 - 0.0043 16.7 7.6 0.0082 15.8 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain UBA_4 PF14555.1 KPI38979.1 - 0.0044 16.5 0.0 0.023 14.2 0.0 2.1 2 0 0 2 2 2 1 UBA-like domain CUE PF02845.11 KPI38979.1 - 0.007 15.8 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain zf-RING_UBOX PF13445.1 KPI38979.1 - 0.13 12.0 6.5 0.3 10.8 4.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger UDPGT PF00201.13 KPI38979.1 - 0.18 10.3 0.1 0.28 9.6 0.1 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase zf-C3HC4_4 PF15227.1 KPI38979.1 - 0.25 11.2 8.5 0.51 10.2 5.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DAO PF01266.19 KPI38980.1 - 2e-37 128.9 0.1 2.4e-37 128.6 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI38980.1 - 0.00016 21.6 0.1 0.00046 20.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI38980.1 - 0.00074 19.4 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI38980.1 - 0.011 15.7 0.0 0.029 14.4 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI38980.1 - 0.023 13.6 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 KPI38980.1 - 0.068 12.0 1.5 0.093 11.5 0.6 1.5 1 1 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KPI38980.1 - 0.068 13.5 0.4 0.15 12.4 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI38980.1 - 0.11 11.3 0.1 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein PhyH PF05721.8 KPI38981.1 - 2.6e-24 86.4 0.0 3.7e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DNA_mis_repair PF01119.14 KPI38982.1 - 5.8e-33 112.8 0.1 1.5e-32 111.5 0.0 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KPI38982.1 - 4.2e-13 49.1 0.0 8.1e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KPI38982.1 - 7.3e-10 38.5 0.0 4.8e-09 35.9 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mito_carr PF00153.22 KPI38983.1 - 3.8e-43 145.1 9.6 1e-15 57.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2788 PF10981.3 KPI38984.1 - 0.0018 18.0 0.2 0.0048 16.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2788) BCHF PF07284.6 KPI38984.1 - 0.059 13.2 1.1 0.082 12.7 0.8 1.1 1 0 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) Nop53 PF07767.6 KPI38986.1 - 1.1e-86 291.2 26.2 1.7e-86 290.6 18.1 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) LDB19 PF13002.2 KPI38987.1 - 7.3e-39 133.2 0.5 1.2e-38 132.4 0.3 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like SARG PF15385.1 KPI38987.1 - 0.013 14.8 3.9 0.025 13.9 2.7 1.3 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Ank_2 PF12796.2 KPI38988.1 - 4.4e-146 475.6 52.6 2.3e-22 79.1 3.0 10.6 4 3 8 12 12 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 KPI38988.1 - 7.8e-109 350.4 24.1 6e-09 35.2 0.2 18.7 18 0 0 18 18 18 16 Ankyrin repeat Ank_3 PF13606.1 KPI38988.1 - 2.8e-73 234.4 12.4 8.7e-05 22.4 0.0 19.2 19 0 0 19 19 18 13 Ankyrin repeat Ank_5 PF13857.1 KPI38988.1 - 2.8e-71 233.9 29.3 7.6e-11 41.8 0.8 15.7 5 5 8 15 15 15 12 Ankyrin repeats (many copies) Ank_4 PF13637.1 KPI38988.1 - 8.4e-68 223.6 10.0 1.4e-08 34.9 0.0 14.2 7 2 8 15 15 15 14 Ankyrin repeats (many copies) NACHT PF05729.7 KPI38988.1 - 1.4e-08 34.5 0.0 4.4e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 KPI38988.1 - 4.1e-05 22.5 0.0 9e-05 21.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KPI38988.1 - 4.8e-05 23.4 0.4 0.00028 20.9 0.3 2.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KPI38988.1 - 0.00019 21.2 0.0 0.011 15.6 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KPI38988.1 - 0.00021 21.4 0.2 0.0016 18.5 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KPI38988.1 - 0.00082 19.2 0.5 0.065 13.1 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KPI38988.1 - 0.0015 18.2 0.0 0.0086 15.8 0.0 2.4 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 KPI38988.1 - 0.0075 16.4 0.1 0.053 13.7 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KPI38988.1 - 0.016 14.9 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 KPI38988.1 - 0.03 15.1 0.1 0.38 11.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain fn3 PF00041.16 KPI38989.1 - 4.4e-08 33.1 0.1 1.1e-07 31.8 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III domain zf-C2H2_4 PF13894.1 KPI38990.1 - 0.24 11.8 4.9 4.6 7.8 1.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger TAF4 PF05236.9 KPI38990.1 - 2.9 7.0 21.0 6.6 5.9 14.6 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family ATP-synt_C PF00137.16 KPI38991.1 - 5.5e-23 80.6 24.9 2.5e-14 52.9 2.0 2.7 3 0 0 3 3 3 2 ATP synthase subunit C Cation_efflux PF01545.16 KPI38991.1 - 0.022 13.8 0.3 0.022 13.8 0.2 2.2 1 1 0 2 2 2 0 Cation efflux family HMG-CoA_red PF00368.13 KPI38992.1 - 0.14 10.8 0.2 0.26 9.9 0.2 1.4 2 0 0 2 2 2 0 Hydroxymethylglutaryl-coenzyme A reductase Rhomboid PF01694.17 KPI38993.1 - 1e-19 71.0 7.9 2.3e-19 69.8 5.5 1.5 1 0 0 1 1 1 1 Rhomboid family Histone_HNS PF00816.16 KPI38993.1 - 0.18 12.2 10.8 0.46 11.0 7.5 1.6 1 0 0 1 1 1 0 H-NS histone family HET PF06985.6 KPI38994.1 - 7.3e-18 65.0 0.0 1.4e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cofilin_ADF PF00241.15 KPI38997.1 - 1.1e-05 25.2 0.0 1.2e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Clr5 PF14420.1 KPI38998.1 - 5.8e-18 64.5 0.1 1.2e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 Clr5 domain TPR_16 PF13432.1 KPI38998.1 - 0.027 15.1 0.4 1.1 9.9 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KPI38998.1 - 0.28 11.9 1.7 9.4 7.1 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Cupin_2 PF07883.6 KPI38999.1 - 5.7e-08 32.1 0.4 1e-07 31.3 0.3 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KPI38999.1 - 0.0016 18.1 0.2 0.0028 17.3 0.1 1.4 1 1 0 1 1 1 1 AraC-like ligand binding domain TRIC PF05197.8 KPI38999.1 - 0.053 12.9 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 TRIC channel MannoseP_isomer PF01050.13 KPI38999.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Git3 PF11710.3 KPI39000.1 - 6.9e-60 202.0 12.4 6.9e-60 202.0 8.6 1.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KPI39000.1 - 1.7e-26 91.7 1.4 4.4e-26 90.4 1.0 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 KPI39000.1 - 2.5e-06 26.8 0.0 6.1e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ABC_tran PF00005.22 KPI39001.1 - 3.6e-22 79.1 0.2 5.4e-10 39.7 0.0 3.4 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KPI39001.1 - 3.3e-09 37.1 0.1 0.0022 18.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KPI39001.1 - 0.0035 17.4 0.1 0.11 12.6 0.0 3.1 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.1 KPI39001.1 - 0.0068 16.2 0.1 0.91 9.4 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KPI39001.1 - 0.0077 15.7 0.2 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KPI39001.1 - 0.047 13.6 3.5 0.41 10.5 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.1 KPI39001.1 - 0.089 13.1 0.4 0.17 12.2 0.3 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KPI39001.1 - 0.15 12.5 0.0 0.39 11.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_17 PF13207.1 KPI39001.1 - 0.17 12.6 0.0 0.59 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 KPI39001.1 - 0.22 10.7 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNase_H2_suC PF08615.6 KPI39003.1 - 5e-23 81.4 0.0 1e-22 80.4 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) NUDIX_2 PF13869.1 KPI39004.1 - 2.8e-51 173.5 0.1 3.3e-51 173.2 0.1 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase AAA PF00004.24 KPI39005.1 - 1.5e-97 322.8 0.0 2.6e-47 160.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KPI39005.1 - 1.2e-19 70.0 0.4 3.4e-19 68.5 0.3 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 KPI39005.1 - 2.2e-14 53.7 0.0 1.1e-07 31.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KPI39005.1 - 4.6e-13 48.7 0.0 1.7e-05 23.9 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KPI39005.1 - 4.9e-13 49.1 0.0 8.5e-06 25.6 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KPI39005.1 - 9.7e-12 45.1 0.3 0.0022 18.1 0.1 4.2 2 2 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KPI39005.1 - 1.2e-11 45.4 0.0 0.00038 21.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KPI39005.1 - 2.6e-11 43.3 0.6 2.8e-05 23.8 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KPI39005.1 - 7e-11 42.4 0.0 0.0018 18.3 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 KPI39005.1 - 1.8e-09 36.7 0.1 0.0011 17.8 0.0 2.7 2 0 0 2 2 2 2 TIP49 C-terminus CDC48_2 PF02933.12 KPI39005.1 - 9.8e-09 34.7 0.1 2.5e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Zeta_toxin PF06414.7 KPI39005.1 - 2.5e-08 33.2 0.1 0.0058 15.7 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin AAA_25 PF13481.1 KPI39005.1 - 6.5e-08 32.2 5.3 0.012 15.0 0.0 4.6 3 2 2 5 5 4 2 AAA domain AAA_14 PF13173.1 KPI39005.1 - 6.8e-08 32.4 0.0 0.0041 17.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KPI39005.1 - 6.8e-08 31.9 0.3 0.0057 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KPI39005.1 - 7.5e-08 31.9 0.1 0.0075 15.7 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 KPI39005.1 - 1.5e-07 31.0 1.2 0.0086 15.8 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 KPI39005.1 - 4.6e-07 29.9 0.0 0.021 14.9 0.0 2.9 2 0 0 2 2 2 2 RNA helicase KaiC PF06745.8 KPI39005.1 - 1.6e-06 27.4 0.9 0.47 9.5 0.0 3.5 2 1 1 3 3 3 2 KaiC DUF815 PF05673.8 KPI39005.1 - 3.1e-06 26.3 0.0 0.0054 15.6 0.0 2.9 3 1 0 3 3 3 2 Protein of unknown function (DUF815) AAA_18 PF13238.1 KPI39005.1 - 3.9e-06 27.2 0.0 0.085 13.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 KPI39005.1 - 3.9e-06 26.6 0.5 0.095 12.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain ResIII PF04851.10 KPI39005.1 - 5e-06 26.4 0.0 0.0048 16.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 KPI39005.1 - 8.3e-06 25.8 0.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KPI39005.1 - 8.4e-06 25.6 0.0 3.6 7.2 0.0 4.1 2 2 2 4 4 4 0 Archaeal ATPase Parvo_NS1 PF01057.12 KPI39005.1 - 1.3e-05 24.1 0.1 0.046 12.5 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NACHT PF05729.7 KPI39005.1 - 3.5e-05 23.5 0.1 0.088 12.4 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Sigma54_activat PF00158.21 KPI39005.1 - 4e-05 23.1 0.1 0.4 10.1 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 KPI39005.1 - 4.8e-05 23.6 0.0 0.17 12.1 0.0 3.5 2 1 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.13 KPI39005.1 - 7.2e-05 22.5 0.0 0.46 10.1 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein Sigma54_activ_2 PF14532.1 KPI39005.1 - 0.00012 22.1 0.0 0.47 10.4 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 KPI39005.1 - 0.00017 20.8 0.4 0.52 9.5 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 KPI39005.1 - 0.0002 20.9 0.0 0.85 9.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KPI39005.1 - 0.00052 19.6 0.0 0.67 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 KPI39005.1 - 0.00076 19.1 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.5 KPI39005.1 - 0.00094 19.0 0.0 0.0035 17.1 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain NB-ARC PF00931.17 KPI39005.1 - 0.0012 17.7 0.1 0.55 9.0 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain DUF2075 PF09848.4 KPI39005.1 - 0.0019 17.2 0.0 1.3 7.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 KPI39005.1 - 0.002 17.8 0.4 1.1 8.9 0.0 4.0 4 0 0 4 4 4 1 NTPase Viral_helicase1 PF01443.13 KPI39005.1 - 0.0034 16.9 0.0 0.3 10.5 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UFD1 PF03152.9 KPI39005.1 - 0.012 14.7 0.0 1.5 7.9 0.0 2.4 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 IPT PF01745.11 KPI39005.1 - 0.014 14.6 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_10 PF12846.2 KPI39005.1 - 0.014 14.8 0.4 1.6 8.0 0.0 3.5 3 1 1 4 4 4 0 AAA-like domain T2SE PF00437.15 KPI39005.1 - 0.017 14.0 0.0 1.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein KAP_NTPase PF07693.9 KPI39005.1 - 0.022 13.7 0.3 2.5 7.0 0.0 3.2 2 2 0 3 3 3 0 KAP family P-loop domain UPF0079 PF02367.12 KPI39005.1 - 0.1 12.2 0.1 9.7 5.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zot PF05707.7 KPI39005.1 - 0.1 12.0 1.3 13 5.2 0.1 3.9 3 1 0 3 3 2 0 Zonular occludens toxin (Zot) Aminotran_1_2 PF00155.16 KPI39006.1 - 8.6e-35 120.3 0.0 9.8e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Tmemb_cc2 PF10267.4 KPI39007.1 - 0.38 9.2 2.5 0.44 9.0 1.7 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF1713 PF08213.6 KPI39008.1 - 1.3e-11 43.8 23.3 1.3e-11 43.8 16.1 2.3 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 KPI39008.1 - 6.3e-05 22.9 0.0 0.00017 21.5 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial protein Pet20 EnY2 PF10163.4 KPI39009.1 - 0.00081 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 Hyd_WA PF06462.7 KPI39009.1 - 0.13 11.9 0.0 0.49 10.0 0.0 1.9 2 0 0 2 2 2 0 Propeller PPR PF01535.15 KPI39009.1 - 0.14 12.2 0.0 0.42 10.6 0.0 1.8 1 0 0 1 1 1 0 PPR repeat Met_10 PF02475.11 KPI39010.1 - 0.00016 21.3 0.0 0.00033 20.3 0.0 1.4 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KPI39010.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain S1 PF00575.18 KPI39011.1 - 8.4e-84 275.6 29.2 5.6e-15 55.1 0.7 13.2 12 1 0 12 12 12 12 S1 RNA binding domain Suf PF05843.9 KPI39011.1 - 1.1e-08 35.2 17.0 4.7e-07 29.8 0.1 4.5 3 1 2 5 5 4 3 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KPI39011.1 - 2.5e-08 33.8 0.5 0.053 14.1 0.0 4.9 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KPI39011.1 - 3.2e-08 33.7 2.0 9.1e-05 22.7 0.1 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KPI39011.1 - 0.00011 22.7 0.4 2.5 8.9 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KPI39011.1 - 0.00017 21.4 0.2 0.79 9.7 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 KPI39011.1 - 0.00072 18.7 3.3 0.0019 17.2 0.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KPI39011.1 - 0.00085 18.9 0.0 0.061 12.9 0.0 2.6 2 0 0 2 2 2 1 TPR repeat S1_2 PF13509.1 KPI39011.1 - 0.0024 17.7 0.0 3.2 7.7 0.0 4.5 4 0 0 4 4 4 1 S1 domain PPR_3 PF13812.1 KPI39011.1 - 0.022 15.0 0.0 2.9 8.4 0.0 3.4 3 0 0 3 3 2 0 Pentatricopeptide repeat domain NRDE-2 PF08424.5 KPI39011.1 - 0.042 12.7 0.2 0.79 8.5 0.0 2.9 2 1 0 2 2 2 0 NRDE-2, necessary for RNA interference PPR_2 PF13041.1 KPI39011.1 - 0.042 13.8 0.0 2.5 8.1 0.0 3.2 3 0 0 3 3 3 0 PPR repeat family TPR_17 PF13431.1 KPI39011.1 - 0.043 14.0 0.0 1.8 8.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.15 KPI39011.1 - 0.046 13.6 0.3 2.6 8.1 0.0 3.5 4 0 0 4 4 3 0 PPR repeat Nop14 PF04147.7 KPI39011.1 - 0.13 10.1 13.4 0.28 9.0 9.3 1.5 1 0 0 1 1 1 0 Nop14-like family SPOB_a PF14689.1 KPI39011.1 - 0.27 10.8 0.0 0.95 9.0 0.0 1.9 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_2 PF07719.12 KPI39011.1 - 0.47 10.4 1.1 27 4.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box PF00646.28 KPI39012.1 - 3.7e-08 32.8 0.1 1.2e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KPI39012.1 - 1.4e-06 27.8 0.1 1e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KPI39012.1 - 0.034 13.8 0.3 0.16 11.7 0.2 2.2 1 1 0 1 1 1 0 F-box-like domain ACCA PF03255.9 KPI39012.1 - 0.11 12.0 0.2 0.2 11.1 0.2 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Pollen_allerg_2 PF01620.11 KPI39013.1 - 0.43 10.8 0.1 0.43 10.8 0.0 3.1 3 1 0 3 3 3 0 Ribonuclease (pollen allergen) Hid1 PF12722.2 KPI39013.1 - 4.8 4.7 11.7 5.8 4.4 8.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pyr_redox_3 PF13738.1 KPI39014.1 - 9.5e-26 91.1 0.0 1.2e-24 87.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI39014.1 - 1.8e-19 69.8 0.2 1.7e-12 46.9 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KPI39014.1 - 3.1e-18 65.2 0.0 3.4e-15 55.2 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KPI39014.1 - 2.2e-14 53.8 0.0 2.7e-12 46.9 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI39014.1 - 1.7e-11 43.6 0.5 0.00015 20.7 0.1 3.5 2 1 1 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KPI39014.1 - 1.2e-08 34.8 1.6 0.025 14.3 0.0 4.1 3 1 1 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KPI39014.1 - 4.5e-07 29.7 0.1 2.8e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KPI39014.1 - 6.9e-07 28.6 0.0 8.7e-06 25.0 0.1 2.1 1 1 1 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KPI39014.1 - 3.1e-06 26.3 1.6 0.035 13.0 0.1 3.4 3 1 0 3 3 3 2 Lycopene cyclase protein Shikimate_DH PF01488.15 KPI39014.1 - 1.5e-05 25.0 0.3 0.21 11.6 0.0 2.6 3 0 0 3 3 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KPI39014.1 - 3.8e-05 24.0 0.2 0.47 10.8 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI39014.1 - 0.00011 21.2 0.3 0.42 9.4 0.0 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.9 KPI39014.1 - 0.00033 19.2 0.1 0.00099 17.6 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein 3HCDH_N PF02737.13 KPI39014.1 - 0.00058 19.5 0.3 0.96 9.0 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KPI39014.1 - 0.00062 19.5 0.3 0.33 10.6 0.0 2.3 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 KPI39014.1 - 0.00099 19.4 2.4 0.4 11.1 0.4 3.1 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KPI39014.1 - 0.0013 17.9 0.1 0.71 9.0 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 KPI39014.1 - 0.0014 17.8 0.1 0.028 13.5 0.0 2.6 3 0 0 3 3 3 1 Thi4 family TrkA_N PF02254.13 KPI39014.1 - 0.0031 17.5 0.2 0.044 13.7 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain ThiF PF00899.16 KPI39014.1 - 0.0036 17.1 0.1 1.4 8.7 0.0 2.5 2 0 0 2 2 2 1 ThiF family FAD_binding_2 PF00890.19 KPI39014.1 - 0.005 15.7 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain IlvN PF07991.7 KPI39014.1 - 0.006 15.9 0.2 3.5 6.9 0.0 2.8 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 KPI39014.1 - 0.05 13.8 0.0 9 6.6 0.0 2.5 3 0 0 3 3 2 0 Putative NAD(P)-binding ApbA PF02558.11 KPI39014.1 - 0.068 12.6 0.0 0.99 8.8 0.0 2.6 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA RRM_1 PF00076.17 KPI39015.1 - 1.1e-14 53.8 0.0 1.7e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI39015.1 - 2.4e-12 46.6 0.0 3.8e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI39015.1 - 1.7e-10 40.6 0.0 2.4e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KPI39015.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif DUF1509 PF07420.6 KPI39015.1 - 0.39 9.9 4.9 0.15 11.3 1.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) MatE PF01554.13 KPI39016.1 - 1.2e-56 190.7 13.2 2.5e-32 111.7 1.2 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KPI39016.1 - 8.8e-06 25.5 5.7 8.8e-06 25.5 4.0 3.7 4 0 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Dispanin PF04505.7 KPI39016.1 - 0.039 13.4 1.2 0.12 11.9 0.8 1.8 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Prefoldin_2 PF01920.15 KPI39017.1 - 1.7e-17 63.0 8.7 2.1e-17 62.8 6.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Mod_r PF07200.8 KPI39017.1 - 0.024 14.5 0.3 0.024 14.5 0.2 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein HAUS5 PF14817.1 KPI39017.1 - 0.092 11.2 6.0 0.1 11.1 4.2 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Pox_A_type_inc PF04508.7 KPI39017.1 - 0.11 12.3 2.6 0.26 11.1 0.2 2.7 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Rootletin PF15035.1 KPI39017.1 - 0.11 12.4 0.3 0.11 12.4 0.2 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion GrpE PF01025.14 KPI39017.1 - 0.4 10.2 4.1 1.5 8.3 0.1 2.1 2 0 0 2 2 2 0 GrpE SlyX PF04102.7 KPI39017.1 - 0.5 10.7 6.4 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 SlyX DUF2681 PF10883.3 KPI39017.1 - 0.78 9.9 7.8 0.83 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) GAS PF13851.1 KPI39017.1 - 0.91 8.6 11.7 1 8.5 3.5 2.1 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding RNA_pol_Rpc34 PF05158.7 KPI39017.1 - 1.5 7.8 5.6 1.1 8.3 2.8 1.4 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit Syntaxin-6_N PF09177.6 KPI39017.1 - 1.6 9.1 5.0 9.1 6.7 3.5 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF743 PF05332.6 KPI39017.1 - 1.8 8.5 6.8 3.6 7.5 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF743) DUF3007 PF11460.3 KPI39017.1 - 2.6 8.1 4.5 1.4 9.0 1.4 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3007) Mnd1 PF03962.10 KPI39017.1 - 6 6.4 9.8 27 4.3 6.8 1.8 1 1 0 1 1 1 0 Mnd1 family Fib_alpha PF08702.5 KPI39017.1 - 6.8 6.8 9.7 5.5 7.1 0.3 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Aldedh PF00171.17 KPI39018.1 - 5.2e-99 331.6 0.0 6.1e-99 331.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SBP_bac_11 PF13531.1 KPI39020.1 - 0.00011 21.9 0.1 0.00016 21.4 0.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein LIP PF03583.9 KPI39021.1 - 0.083 12.0 0.2 0.18 10.9 0.1 1.5 1 0 0 1 1 1 0 Secretory lipase DNA_pol_A_exo1 PF01612.15 KPI39022.1 - 0.00068 19.1 0.0 0.036 13.5 0.0 2.2 1 1 0 1 1 1 1 3'-5' exonuclease ABC_tran PF00005.22 KPI39024.1 - 5.7e-42 143.2 0.1 1.8e-26 93.1 0.0 3.2 2 1 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 KPI39024.1 - 7e-41 139.6 30.4 1.9e-26 92.5 6.5 2.3 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.1 KPI39024.1 - 1.7e-16 61.0 0.1 0.0019 18.2 0.0 4.2 4 0 0 4 4 4 4 AAA domain AAA_25 PF13481.1 KPI39024.1 - 2.7e-10 39.9 1.2 9.3e-05 21.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KPI39024.1 - 6.5e-10 38.4 1.3 0.00013 21.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KPI39024.1 - 5.3e-09 36.3 3.5 0.00052 20.0 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KPI39024.1 - 2.3e-08 34.6 4.4 0.0026 18.1 0.4 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KPI39024.1 - 7.1e-08 31.9 1.7 0.61 9.2 0.0 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KPI39024.1 - 1.4e-07 30.8 6.1 0.0024 17.3 1.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.1 KPI39024.1 - 2.6e-07 30.7 0.0 0.0043 17.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KPI39024.1 - 2.7e-07 30.8 0.1 0.021 14.9 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KPI39024.1 - 6.8e-07 30.1 0.0 0.073 13.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KPI39024.1 - 8.6e-07 28.6 0.3 0.0025 17.3 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_15 PF13175.1 KPI39024.1 - 1e-06 28.1 0.0 0.13 11.3 0.0 4.0 4 0 0 4 4 4 1 AAA ATPase domain AAA_18 PF13238.1 KPI39024.1 - 5.2e-05 23.5 0.0 0.26 11.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KPI39024.1 - 0.00011 22.1 0.0 0.57 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KPI39024.1 - 0.00013 21.6 0.2 0.42 10.2 0.0 2.9 3 0 0 3 3 2 2 NACHT domain AAA_19 PF13245.1 KPI39024.1 - 0.00017 21.2 0.7 0.07 12.8 0.3 2.8 2 0 0 2 2 2 1 Part of AAA domain MMR_HSR1 PF01926.18 KPI39024.1 - 0.00027 20.8 0.7 0.73 9.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 KPI39024.1 - 0.0006 19.5 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ABC_ATPase PF09818.4 KPI39024.1 - 0.00061 18.4 0.2 0.016 13.7 0.1 2.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class cobW PF02492.14 KPI39024.1 - 0.00091 18.7 0.6 0.52 9.7 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 KPI39024.1 - 0.0013 19.1 0.0 1.2 9.6 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein Arch_ATPase PF01637.13 KPI39024.1 - 0.0021 17.8 0.0 0.51 9.9 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase FtsK_SpoIIIE PF01580.13 KPI39024.1 - 0.0027 17.2 1.2 2.2 7.6 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_30 PF13604.1 KPI39024.1 - 0.0031 17.1 0.5 0.94 9.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KPI39024.1 - 0.0034 17.2 0.2 3.2 7.7 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 KPI39024.1 - 0.0058 16.3 0.9 0.71 9.5 0.1 3.3 4 0 0 4 4 4 1 NTPase T2SE PF00437.15 KPI39024.1 - 0.0071 15.2 1.0 1.6 7.6 0.4 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.1 KPI39024.1 - 0.0078 16.1 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 KPI39024.1 - 0.0089 15.5 0.1 2.9 7.3 0.1 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 KPI39024.1 - 0.0096 15.4 0.1 10 5.6 0.0 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 KPI39024.1 - 0.01 16.0 0.1 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase PDR_assoc PF08370.6 KPI39024.1 - 0.013 14.9 0.7 0.037 13.5 0.1 2.0 2 0 0 2 2 1 0 Plant PDR ABC transporter associated DUF87 PF01935.12 KPI39024.1 - 0.013 15.2 1.3 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 KPI39024.1 - 0.029 13.8 0.0 0.4 10.1 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 KPI39024.1 - 0.039 13.7 0.3 11 5.7 0.0 2.9 3 0 0 3 3 3 0 Dynamin family AAA_5 PF07728.9 KPI39024.1 - 0.042 13.5 0.0 9.5 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KPI39024.1 - 0.048 13.2 0.4 6.3 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KPI39024.1 - 0.062 12.1 0.2 1.8 7.3 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.13 KPI39024.1 - 0.087 11.8 0.2 2.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Septin Pox_A32 PF04665.7 KPI39024.1 - 0.15 11.3 0.9 1.2 8.3 0.1 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein Rad17 PF03215.10 KPI39024.1 - 0.36 9.4 0.0 11 4.5 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein MFS_1 PF07690.11 KPI39025.1 - 4.5e-29 101.2 18.9 4.5e-29 101.2 13.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KPI39025.1 - 0.00017 21.2 0.5 0.00045 19.9 0.3 1.8 1 0 0 1 1 1 1 MFS_1 like family Ost4 PF10215.4 KPI39027.1 - 3.5e-18 64.7 1.7 6.1e-18 64.0 1.2 1.4 1 0 0 1 1 1 1 Oligosaccaryltransferase Pyr_redox_2 PF07992.9 KPI39028.1 - 3.9e-21 75.8 0.0 5.4e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI39028.1 - 5.9e-13 49.0 0.0 1.1e-10 41.6 0.0 3.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 KPI39028.1 - 9.5e-06 24.5 0.0 2.4e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KPI39028.1 - 7.5e-05 22.2 0.2 0.00027 20.5 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 KPI39028.1 - 0.00012 22.1 0.1 0.00035 20.6 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KPI39028.1 - 0.0003 20.0 0.2 0.00081 18.6 0.1 1.8 1 0 0 1 1 1 1 EF hand Surfac_D-trimer PF09006.6 KPI39028.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation UPF0160 PF03690.8 KPI39030.1 - 1.2e-113 379.7 0.0 1.4e-113 379.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) P5CR_dimer PF14748.1 KPI39031.1 - 1.4e-18 66.8 2.9 3.6e-18 65.5 2.0 1.7 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KPI39031.1 - 5.1e-14 52.4 1.4 1.2e-13 51.2 0.9 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KPI39031.1 - 3.5e-07 29.7 0.2 5.5e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KPI39031.1 - 0.00096 18.9 0.2 0.0018 18.0 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DapB_N PF01113.15 KPI39031.1 - 0.0092 15.9 0.3 0.019 14.8 0.2 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.15 KPI39031.1 - 0.034 14.2 0.2 0.073 13.1 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Adeno_PX PF05829.7 KPI39031.1 - 0.28 10.6 5.6 0.61 9.6 3.8 1.5 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) Mito_carr PF00153.22 KPI39032.1 - 1.6e-59 197.6 0.4 3.3e-23 81.1 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein CPSase_L_D2 PF02786.12 KPI39034.1 - 3.6e-113 376.0 0.3 1.5e-83 279.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 KPI39034.1 - 2.2e-46 156.6 0.0 4.6e-46 155.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KPI39034.1 - 1.4e-44 151.8 0.0 3.1e-44 150.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_chain PF00289.17 KPI39034.1 - 3.6e-42 142.9 0.0 4.3e-21 75.0 0.0 3.0 3 0 0 3 3 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 KPI39034.1 - 4.5e-42 142.7 0.0 1.1e-41 141.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace_N PF02729.16 KPI39034.1 - 4.8e-41 139.7 0.0 9.4e-41 138.7 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ATP-grasp_4 PF13535.1 KPI39034.1 - 2.1e-36 125.3 0.3 9.3e-22 77.6 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 KPI39034.1 - 1.7e-33 115.7 0.0 5.5e-33 114.0 0.0 2.0 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 KPI39034.1 - 1.4e-20 73.3 0.1 3.8e-09 35.7 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KPI39034.1 - 2.2e-18 66.3 0.5 3.6e-09 36.2 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.17 KPI39034.1 - 2.5e-18 65.8 0.0 1.1e-17 63.7 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.17 KPI39034.1 - 8.9e-17 60.9 0.2 2.4e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 KPI39034.1 - 4.8e-07 29.4 0.0 0.00057 19.4 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Peptidase_C26 PF07722.8 KPI39034.1 - 1.1e-06 28.2 0.5 6.1e-05 22.5 0.1 3.1 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.9 KPI39034.1 - 1.3e-06 28.3 0.4 0.047 13.5 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.19 KPI39034.1 - 0.0018 17.7 0.0 0.0097 15.3 0.0 2.2 2 0 0 2 2 2 1 DJ-1/PfpI family zf-RING_2 PF13639.1 KPI39035.1 - 8.4e-11 41.5 0.0 1.7e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KPI39035.1 - 3.2e-06 27.1 1.3 6.4e-06 26.1 0.9 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KPI39035.1 - 0.00014 21.4 1.1 0.056 13.1 0.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI39035.1 - 0.00031 20.6 2.1 0.15 12.1 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KPI39035.1 - 0.0099 15.7 6.2 0.5 10.2 4.3 2.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KPI39035.1 - 0.011 15.4 2.7 1.2 8.9 0.0 2.4 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 KPI39035.1 - 0.016 14.8 3.3 0.57 9.8 0.1 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Tmpp129 PF10272.4 KPI39035.1 - 0.18 10.4 0.5 0.3 9.7 0.3 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-RING_4 PF14570.1 KPI39035.1 - 7.6 6.2 6.9 14 5.3 1.9 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Wyosine_form PF08608.7 KPI39036.1 - 3.8e-23 81.3 0.0 8e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 KPI39036.1 - 1.1e-13 51.7 0.0 2.1e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily RTA1 PF04479.8 KPI39037.1 - 7.2e-05 22.3 4.5 7.2e-05 22.3 3.1 2.1 1 1 0 2 2 2 1 RTA1 like protein DUF2976 PF11190.3 KPI39037.1 - 0.025 14.0 0.4 0.025 14.0 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) DUF4577 PF15145.1 KPI39037.1 - 0.21 11.5 1.2 3 7.7 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4577) ADH_zinc_N PF00107.21 KPI39038.1 - 3e-30 104.4 0.0 4.5e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI39038.1 - 3e-16 60.4 0.0 5.4e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI39038.1 - 6.9e-12 45.0 0.0 1.8e-09 37.3 0.0 2.9 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain CoA_trans PF01144.18 KPI39038.1 - 0.093 11.9 0.1 0.27 10.3 0.0 1.7 1 1 0 2 2 2 0 Coenzyme A transferase NAD_binding_10 PF13460.1 KPI39038.1 - 0.094 12.7 0.1 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding DUF1772 PF08592.6 KPI39039.1 - 4.7e-15 55.5 4.5 5.7e-15 55.2 3.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) IATP PF04568.7 KPI39040.1 - 0.025 14.6 0.4 0.025 14.6 0.3 1.6 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Nop14 PF04147.7 KPI39040.1 - 2.1 6.1 7.4 2.4 5.9 5.2 1.0 1 0 0 1 1 1 0 Nop14-like family NMD3 PF04981.8 KPI39041.1 - 1.2e-72 243.8 4.0 1.7e-72 243.4 2.8 1.2 1 0 0 1 1 1 1 NMD3 family FAD_binding_1 PF00667.15 KPI39042.1 - 3.7e-66 222.7 0.0 5.3e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KPI39042.1 - 2.7e-36 124.7 0.4 5e-36 123.8 0.3 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KPI39042.1 - 4.1e-21 75.5 0.0 3.3e-20 72.6 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KPI39042.1 - 0.069 13.1 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain Ank_2 PF12796.2 KPI39043.1 - 1.4e-53 179.1 7.6 6.2e-20 71.3 0.2 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KPI39043.1 - 8.7e-35 118.4 10.2 4.4e-09 36.6 0.1 5.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 KPI39043.1 - 1.9e-32 109.4 5.1 5.9e-06 25.8 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 KPI39043.1 - 7.4e-31 105.4 3.6 2.9e-08 33.6 0.1 5.7 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI39043.1 - 5.2e-27 91.2 0.9 0.00078 19.4 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat DUF1843 PF08898.5 KPI39043.1 - 0.01 15.8 2.8 17 5.5 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) DUF2518 PF10726.4 KPI39044.1 - 0.043 13.3 1.0 6.3 6.3 0.0 3.1 2 1 1 3 3 3 0 Protein of function (DUF2518) SQS_PSY PF00494.14 KPI39045.1 - 3.6e-40 137.9 0.0 4.8e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase MFS_1 PF07690.11 KPI39046.1 - 4.1e-33 114.5 26.3 5.7e-33 114.0 18.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1049 PF06305.6 KPI39046.1 - 0.11 12.0 1.7 0.84 9.1 0.1 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Fungal_trans_2 PF11951.3 KPI39048.1 - 1.8e-40 138.7 0.1 9.5e-40 136.3 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI39048.1 - 0.00023 20.9 1.0 0.00045 20.0 0.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KPI39049.1 - 3e-25 88.7 46.1 3e-25 88.7 31.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_2 PF07992.9 KPI39051.1 - 9.4e-38 130.1 0.4 1.3e-37 129.6 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KPI39051.1 - 4.2e-26 91.1 0.3 7.5e-26 90.3 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KPI39051.1 - 1.6e-14 54.0 2.3 2.5e-14 53.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI39051.1 - 0.0084 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KPI39051.1 - 0.077 11.8 5.0 0.12 11.1 1.8 2.6 2 1 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KPI39051.1 - 0.22 10.3 5.6 5.2 5.7 1.4 2.6 3 0 0 3 3 3 0 FAD binding domain EF-hand_6 PF13405.1 KPI39052.1 - 1.2e-09 37.2 0.3 0.0013 18.4 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KPI39052.1 - 0.00011 21.2 0.1 0.0048 16.0 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KPI39052.1 - 0.0018 18.3 0.6 0.0018 18.3 0.4 2.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KPI39052.1 - 0.0028 16.9 0.1 0.21 10.9 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KPI39052.1 - 0.0055 16.3 0.9 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain pair PAS_3 PF08447.6 KPI39052.1 - 0.17 11.9 2.2 1.5 8.9 1.1 2.2 2 0 0 2 2 2 0 PAS fold Pkinase PF00069.20 KPI39053.1 - 1.2e-59 201.6 0.0 1.9e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI39053.1 - 9.9e-24 83.8 0.0 1.8e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KPI39053.1 - 0.0035 17.1 0.0 0.0087 15.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KPI39053.1 - 0.13 11.2 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FTZ PF03867.9 KPI39054.1 - 0.092 11.9 2.3 0.2 10.8 1.6 1.6 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Cytomega_UL20A PF05984.7 KPI39054.1 - 3.8 7.7 11.1 0.19 11.9 1.8 2.6 1 1 1 2 2 2 0 Cytomegalovirus UL20A protein Metallophos PF00149.23 KPI39055.1 - 2e-36 125.2 0.6 3.6e-29 101.5 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Flu_NS2 PF00601.14 KPI39057.1 - 0.029 14.5 1.7 4.3 7.6 0.0 2.7 2 1 0 2 2 2 0 Influenza non-structural protein (NS2) DUF2075 PF09848.4 KPI39057.1 - 0.047 12.6 0.5 0.059 12.3 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DivIC PF04977.10 KPI39057.1 - 0.35 10.3 2.7 1.5 8.3 0.9 2.2 2 0 0 2 2 2 0 Septum formation initiator WD40 PF00400.27 KPI39058.1 - 2.4e-19 68.4 11.7 6.6e-05 22.6 0.1 5.8 5 1 0 5 5 5 5 WD domain, G-beta repeat TAXi_C PF14541.1 KPI39059.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal RhoGEF PF00621.15 KPI39060.1 - 3.5e-09 36.7 0.1 9.6e-09 35.3 0.0 1.6 1 1 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.3 KPI39060.1 - 1.8e-06 27.5 0.0 3.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DUF2413 PF10310.4 KPI39060.1 - 8.4 5.0 7.9 8.9 4.9 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) Zn_clus PF00172.13 KPI39061.1 - 4.9e-07 29.5 7.6 4.9e-07 29.5 5.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KPI39061.1 - 0.034 12.7 0.0 0.052 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glyco_hydro_47 PF01532.15 KPI39062.1 - 1e-152 508.9 0.2 1.3e-152 508.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Sugar_tr PF00083.19 KPI39063.1 - 8.9e-95 317.8 29.1 1.3e-94 317.3 20.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI39063.1 - 6.5e-18 64.5 42.2 3e-15 55.8 26.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FMN_dh PF01070.13 KPI39065.1 - 7e-116 386.9 0.0 9e-116 386.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KPI39065.1 - 5.7e-05 22.1 0.0 0.006 15.5 0.1 2.6 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KPI39065.1 - 6.9e-05 22.0 0.3 0.052 12.6 0.0 2.3 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 KPI39065.1 - 0.0024 16.8 0.2 0.0036 16.2 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 KPI39065.1 - 0.0042 16.2 0.9 0.0075 15.4 0.6 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Npa1 PF11707.3 KPI39066.1 - 1e-65 221.9 0.0 4e-65 219.9 0.0 2.0 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal DUF3535 PF12054.3 KPI39066.1 - 0.0097 14.5 0.8 0.017 13.7 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) HEAT PF02985.17 KPI39066.1 - 0.091 12.8 1.3 1.4 9.2 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat IF-2B PF01008.12 KPI39068.1 - 1.1e-59 201.7 0.0 2.1e-59 200.8 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF746 PF05344.6 KPI39068.1 - 0.002 17.6 0.0 0.0057 16.1 0.0 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF746) DUF2470 PF10615.4 KPI39069.1 - 1.4e-13 50.8 0.0 2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) FAD_binding_3 PF01494.14 KPI39070.1 - 1.2e-22 80.4 1.5 3.8e-22 78.8 1.1 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI39070.1 - 1.1e-13 50.8 2.7 3e-10 39.5 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI39070.1 - 1.7e-10 40.7 0.6 7.4e-10 38.7 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KPI39070.1 - 8.3e-08 32.5 0.2 2.6e-07 30.9 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI39070.1 - 1.3e-07 30.8 0.4 1.3e-06 27.5 0.3 2.1 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KPI39070.1 - 9e-06 25.6 0.1 2.1e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KPI39070.1 - 1.1e-05 24.9 0.4 2.3e-05 23.8 0.3 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 KPI39070.1 - 7.7e-05 21.5 1.1 0.036 12.6 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 KPI39070.1 - 0.00021 21.4 0.1 0.0012 18.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI39070.1 - 0.00034 19.5 0.5 0.0005 19.0 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KPI39070.1 - 0.00038 19.6 0.0 0.00072 18.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KPI39070.1 - 0.0015 17.7 0.7 0.0019 17.3 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KPI39070.1 - 0.0037 16.9 0.0 0.0092 15.6 0.1 1.6 2 0 0 2 2 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KPI39070.1 - 0.0078 16.3 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 KPI39070.1 - 0.0079 15.1 0.1 0.017 14.0 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KPI39070.1 - 0.0092 14.4 0.1 0.014 13.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_10 PF13460.1 KPI39070.1 - 0.032 14.2 0.1 0.074 13.0 0.1 1.5 1 1 0 1 1 1 0 NADH(P)-binding AlaDh_PNT_C PF01262.16 KPI39070.1 - 0.051 13.1 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 KPI39070.1 - 0.054 13.7 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 KPI39070.1 - 0.069 12.9 0.2 0.26 11.0 0.1 2.0 2 0 0 2 2 2 0 ThiF family UDPG_MGDP_dh_N PF03721.9 KPI39070.1 - 0.072 12.4 0.3 0.39 10.0 0.1 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KPI39070.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Smg4_UPF3 PF03467.10 KPI39071.1 - 4.2e-16 59.4 0.0 1.2e-15 57.9 0.0 1.8 1 1 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.17 KPI39071.1 - 4.3e-09 35.8 0.1 4.1e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI39071.1 - 7.8e-08 32.0 0.1 2.1e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI39071.1 - 1.7e-06 27.9 0.0 5.4e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KPI39071.1 - 0.042 13.6 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KPI39071.1 - 0.13 12.1 1.7 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif RAM PF15320.1 KPI39071.1 - 0.4 10.9 3.5 1.2 9.5 2.4 1.7 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Fungal_trans PF04082.13 KPI39072.1 - 6.4e-07 28.4 0.2 1e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNA_Me_trans PF04252.8 KPI39073.1 - 8.9e-45 152.5 0.0 1.1e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Ribosomal_L11_N PF03946.9 KPI39074.1 - 6.8e-27 92.7 0.1 1.6e-26 91.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KPI39074.1 - 1.3e-24 86.0 0.6 2.6e-24 85.1 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Pkinase PF00069.20 KPI39075.1 - 6.5e-33 113.9 0.0 6.7e-21 74.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KPI39075.1 - 1.1e-12 47.5 0.0 4.9e-11 42.1 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.11 KPI39076.1 - 2.1e-34 118.7 29.1 2e-33 115.5 20.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Mannosyl_trans3 PF11051.3 KPI39077.1 - 2.3e-67 227.1 0.0 5.9e-67 225.8 0.0 1.7 2 1 0 2 2 2 1 Mannosyltransferase putative Ycf1 PF05758.7 KPI39077.1 - 0.79 7.3 7.9 1 6.9 5.4 1.1 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 KPI39077.1 - 2.4 6.6 8.4 3.6 6.1 5.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein bZIP_2 PF07716.10 KPI39078.1 - 5.6e-07 29.2 4.9 5.6e-07 29.2 3.4 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 KPI39078.1 - 5.8e-07 29.3 7.8 1.7e-06 27.8 5.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KPI39078.1 - 0.0024 18.1 6.1 0.0024 18.1 4.3 2.4 3 0 0 3 3 3 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.6 KPI39078.1 - 0.44 9.6 4.6 0.77 8.8 3.2 1.4 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4045 PF13254.1 KPI39079.1 - 2.2e-95 320.3 36.8 2.2e-95 320.3 25.5 5.3 4 2 0 4 4 4 1 Domain of unknown function (DUF4045) Gelsolin PF00626.17 KPI39079.1 - 1.3e-06 27.9 0.0 0.0051 16.4 0.0 2.7 2 0 0 2 2 2 2 Gelsolin repeat Aminotran_3 PF00202.16 KPI39081.1 - 2.2e-40 138.5 0.0 4.6e-39 134.2 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-III MIP PF00230.15 KPI39083.1 - 6.3e-24 84.6 5.0 2.3e-23 82.8 3.4 1.8 1 1 0 1 1 1 1 Major intrinsic protein V-ATPase_H_N PF03224.9 KPI39084.1 - 4.1e-82 275.7 0.1 6.2e-82 275.2 0.1 1.3 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KPI39084.1 - 7.7e-40 135.5 0.3 4.3e-39 133.0 0.0 2.4 3 0 0 3 3 3 1 V-ATPase subunit H DUF619 PF04768.8 KPI39084.1 - 0.069 12.5 0.1 5 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF619) HEAT PF02985.17 KPI39084.1 - 0.11 12.6 0.0 0.8 9.9 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat DUF2680 PF10925.3 KPI39084.1 - 1.8 8.4 5.2 3.6 7.5 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) Ribosomal_L7Ae PF01248.21 KPI39085.1 - 3.1e-26 90.7 0.1 3.9e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KPI39085.1 - 0.00024 20.9 0.0 0.00025 20.9 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 KPI39085.1 - 0.0051 16.5 0.0 0.0062 16.2 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain TMF_TATA_bd PF12325.3 KPI39086.1 - 1.4e-39 134.5 9.4 1.4e-39 134.5 6.5 6.6 2 1 3 7 7 7 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KPI39086.1 - 2.4e-09 36.8 11.8 2.4e-09 36.8 8.2 8.1 7 1 0 8 8 8 3 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KPI39086.1 - 0.0049 16.4 5.2 0.0049 16.4 3.6 5.1 2 1 2 4 4 4 1 IncA protein Atg14 PF10186.4 KPI39086.1 - 0.0049 15.8 4.5 0.0049 15.8 3.1 4.7 2 1 3 5 5 5 1 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 KPI39086.1 - 0.017 15.4 0.7 0.017 15.4 0.5 8.8 3 3 4 9 9 9 0 SlyX ATG16 PF08614.6 KPI39086.1 - 1 9.1 77.4 0.028 14.2 3.7 4.6 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Thionin PF00321.12 KPI39087.1 - 5.4 7.3 8.2 5.5 7.2 1.3 2.7 2 0 0 2 2 2 0 Plant thionin Glyco_hydro_cc PF11790.3 KPI39088.1 - 1.1e-26 93.6 0.7 2.5e-18 66.4 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase catalytic core UPF0052 PF01933.13 KPI39089.1 - 3.5e-51 174.3 0.0 4.7e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 RNA_pol_Rpb1_6 PF04992.9 KPI39090.1 - 0.042 13.5 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 F-box-like PF12937.2 KPI39092.1 - 2e-09 37.0 0.1 4.6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KPI39092.1 - 3.3e-09 36.1 0.0 8.1e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain Methyltransf_23 PF13489.1 KPI39092.1 - 0.0018 18.0 0.0 0.006 16.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI39092.1 - 0.047 14.2 0.0 0.16 12.5 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Aminotran_5 PF00266.14 KPI39092.1 - 0.1 11.2 0.9 6.3 5.4 0.1 2.2 2 0 0 2 2 2 0 Aminotransferase class-V Methyltransf_32 PF13679.1 KPI39092.1 - 0.21 11.2 0.0 0.51 10.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KPI39092.1 - 0.24 11.0 0.0 0.46 10.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UIM PF02809.15 KPI39092.1 - 3.9 7.2 9.5 5.5 6.8 2.0 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif UvrD-helicase PF00580.16 KPI39093.1 - 6.7e-09 35.4 1.9 0.00012 21.5 0.1 2.7 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 KPI39093.1 - 2.1e-06 27.4 0.0 0.0012 18.3 0.0 2.3 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KPI39093.1 - 1.4e-05 24.6 0.7 0.00066 19.3 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 KPI39093.1 - 0.00012 21.9 0.2 0.0003 20.6 0.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KPI39093.1 - 0.00096 18.7 0.0 0.0023 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.12 KPI39093.1 - 0.0012 18.8 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF83 UvrD_C_2 PF13538.1 KPI39093.1 - 0.0014 18.6 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 KPI39093.1 - 0.0015 18.0 0.0 0.017 14.6 0.0 2.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KPI39093.1 - 0.0024 17.4 0.2 0.0087 15.5 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Methyltransf_4 PF02390.12 KPI39093.1 - 0.0099 14.9 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase T2SE PF00437.15 KPI39093.1 - 0.012 14.5 0.0 0.26 10.1 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_11 PF13086.1 KPI39093.1 - 0.028 13.9 0.0 0.085 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain Herpes_ori_bp PF02399.10 KPI39093.1 - 0.12 10.3 0.0 0.18 9.7 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein AAA_22 PF13401.1 KPI39093.1 - 0.15 12.1 0.0 0.45 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Fungal_trans_2 PF11951.3 KPI39094.1 - 2.3e-28 98.9 9.5 6.3e-28 97.4 6.6 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Epimerase PF01370.16 KPI39096.1 - 2.3e-47 161.4 0.0 3.1e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI39096.1 - 1.7e-19 69.6 0.0 2.5e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KPI39096.1 - 1.1e-13 50.7 0.0 6.2e-12 45.0 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KPI39096.1 - 9.8e-13 47.6 0.0 1.4e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KPI39096.1 - 6.9e-11 41.5 0.0 3.8e-10 39.1 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KPI39096.1 - 4.5e-10 39.7 0.0 7.4e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KPI39096.1 - 1.5e-08 34.9 0.0 2.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KPI39096.1 - 5e-08 32.8 0.0 1.4e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 KPI39096.1 - 0.00056 19.2 0.1 0.0022 17.2 0.1 1.8 1 1 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 KPI39096.1 - 0.0077 15.6 0.1 0.014 14.7 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 KPI39096.1 - 0.049 12.5 0.3 0.1 11.5 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Cys_Met_Meta_PP PF01053.15 KPI39096.1 - 0.17 10.1 0.0 0.39 8.9 0.0 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme HET PF06985.6 KPI39097.1 - 9.9e-11 41.9 0.0 1.2e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PX PF00787.19 KPI39098.1 - 1.2e-15 57.2 0.5 3.8e-15 55.6 0.1 2.0 2 0 0 2 2 2 1 PX domain Metallophos PF00149.23 KPI39099.1 - 8.3e-44 149.3 0.8 1e-43 149.0 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HET PF06985.6 KPI39100.1 - 1.8e-23 83.2 0.2 3e-23 82.5 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EMP24_GP25L PF01105.19 KPI39101.1 - 0.041 13.5 0.5 0.069 12.8 0.3 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD NfeD PF01957.13 KPI39101.1 - 8.6 6.4 9.6 3.3 7.8 2.6 2.3 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding CN_hydrolase PF00795.17 KPI39102.1 - 1.5e-09 37.5 0.0 3.1e-09 36.4 0.0 1.6 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_17 PF00332.13 KPI39102.1 - 0.00033 19.8 0.4 0.00077 18.5 0.3 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 LRR_8 PF13855.1 KPI39103.1 - 1.2e-41 140.2 36.4 3.2e-08 33.2 0.2 10.1 7 3 2 9 9 9 7 Leucine rich repeat LRR_4 PF12799.2 KPI39103.1 - 5.6e-39 131.1 41.3 4.3e-07 29.4 1.2 11.7 7 3 5 12 12 12 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KPI39103.1 - 1.8e-30 100.2 40.2 0.091 12.8 0.6 17.3 17 2 1 18 18 18 9 Leucine Rich Repeat LRR_7 PF13504.1 KPI39103.1 - 6.2e-16 55.7 48.7 1 9.8 0.0 17.3 20 0 0 20 20 20 6 Leucine rich repeat LRR_6 PF13516.1 KPI39103.1 - 2e-13 48.8 39.6 0.16 12.1 0.1 13.7 15 1 0 15 15 15 7 Leucine Rich repeat LRR_9 PF14580.1 KPI39103.1 - 8.8e-07 28.6 4.0 0.00017 21.2 0.0 3.5 1 1 0 3 3 3 1 Leucine-rich repeat LRR_5 PF13306.1 KPI39103.1 - 0.004 16.8 0.2 2.4 7.8 0.1 3.4 2 2 0 3 3 3 1 Leucine rich repeats (6 copies) Pentapeptide_4 PF13599.1 KPI39103.1 - 0.034 13.9 0.3 7.7 6.3 0.0 4.1 4 1 0 4 4 4 0 Pentapeptide repeats (9 copies) DUF3445 PF11927.3 KPI39105.1 - 1.3e-70 237.6 0.0 1.6e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Ras PF00071.17 KPI39106.1 - 4e-59 198.6 0.1 4.8e-59 198.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KPI39106.1 - 8.8e-19 68.1 0.0 1.2e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KPI39106.1 - 3.3e-08 32.9 0.0 3.8e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KPI39106.1 - 1.8e-07 30.7 0.1 8.1e-07 28.6 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KPI39106.1 - 0.0012 18.8 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF2075 PF09848.4 KPI39106.1 - 0.025 13.5 0.1 0.23 10.4 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Gtr1_RagA PF04670.7 KPI39106.1 - 0.029 13.5 0.1 0.037 13.1 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF258 PF03193.11 KPI39106.1 - 0.065 12.4 0.1 0.11 11.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KPI39106.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KPI39106.1 - 0.18 11.2 0.4 0.71 9.2 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 KPI39106.1 - 0.4 10.1 2.0 4 6.8 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Peptidase_C12 PF01088.16 KPI39107.1 - 2.2e-63 213.3 0.0 2.4e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 AAA_10 PF12846.2 KPI39109.1 - 1e-08 35.0 0.0 1.3e-06 28.0 0.0 2.3 1 1 0 1 1 1 1 AAA-like domain FtsK_SpoIIIE PF01580.13 KPI39109.1 - 0.00026 20.5 0.0 0.36 10.2 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.1 KPI39109.1 - 0.0062 16.6 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KPI39109.1 - 0.0075 15.3 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.24 KPI39109.1 - 0.008 16.3 0.1 0.054 13.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.7 KPI39109.1 - 0.0086 15.5 0.0 0.22 10.9 0.0 2.2 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) DUF87 PF01935.12 KPI39109.1 - 0.053 13.3 0.0 0.25 11.1 0.0 2.2 1 1 0 1 1 1 0 Domain of unknown function DUF87 Metallophos PF00149.23 KPI39110.1 - 4.2e-37 127.4 0.0 6.5e-36 123.6 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KPI39110.1 - 0.015 15.1 0.0 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Flavodoxin_1 PF00258.20 KPI39111.1 - 5.5e-07 29.6 0.0 1.6e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Flavodoxin CMAS PF02353.15 KPI39113.1 - 1e-70 237.9 0.0 2.3e-70 236.8 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KPI39113.1 - 2e-09 37.3 0.0 3.6e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI39113.1 - 4.8e-08 33.5 0.0 9.6e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI39113.1 - 1.6e-06 27.8 0.0 2.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI39113.1 - 5.6e-06 26.7 0.0 9.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI39113.1 - 3.6e-05 23.7 0.0 6.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI39113.1 - 0.00041 20.7 0.0 0.00082 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KPI39113.1 - 0.008 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 KPI39113.1 - 0.058 12.4 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Svf1 PF08622.5 KPI39114.1 - 5.7e-118 393.6 0.4 6.5e-118 393.4 0.3 1.0 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 KPI39114.1 - 0.05 12.8 0.1 0.066 12.5 0.1 1.2 1 0 0 1 1 1 0 Hydroxyneurosporene synthase (CrtC) Isy1 PF06246.7 KPI39115.1 - 6.7e-73 245.2 8.3 1.1e-72 244.5 5.7 1.3 1 1 0 1 1 1 1 Isy1-like splicing family DUF904 PF06005.7 KPI39115.1 - 0.17 12.2 0.3 0.17 12.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) ECH_C PF13766.1 KPI39116.1 - 8.4e-37 125.9 0.0 1.6e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KPI39116.1 - 6.9e-26 90.8 0.0 1.3e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Kei1 PF08552.6 KPI39117.1 - 1.6e-47 161.6 0.5 1.6e-47 161.6 0.4 1.7 2 0 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 SPC12 PF06645.8 KPI39117.1 - 0.89 9.4 4.8 0.94 9.3 1.7 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Dabb PF07876.7 KPI39119.1 - 2.4e-05 24.6 0.0 2.8e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain MOR2-PAG1_N PF14222.1 KPI39120.1 - 8e-161 536.4 0.0 1.4e-160 535.6 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KPI39120.1 - 3.6e-86 289.1 0.1 3.6e-86 289.1 0.0 2.8 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KPI39120.1 - 7.6e-28 96.6 8.3 2.1e-13 48.8 0.0 4.4 1 1 2 3 3 3 3 Cell morphogenesis central region Fungal_trans_2 PF11951.3 KPI39121.1 - 2e-06 26.6 0.1 7.1e-05 21.5 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Calcyon PF06387.6 KPI39121.1 - 0.19 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) Borrelia_P83 PF05262.6 KPI39122.1 - 0.18 10.0 17.7 0.2 9.8 12.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_C37 PF05416.7 KPI39122.1 - 0.38 8.9 11.5 0.52 8.5 7.9 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase PLRV_ORF5 PF01690.12 KPI39122.1 - 0.96 8.5 10.3 1.4 7.9 7.1 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4192 PF13830.1 KPI39122.1 - 1.5 8.3 13.2 3.3 7.2 9.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) RR_TM4-6 PF06459.7 KPI39122.1 - 1.6 8.5 12.9 2.6 7.8 8.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.11 KPI39122.1 - 3.3 7.0 11.7 5.8 6.2 8.1 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 ATP-synt_C PF00137.16 KPI39124.1 - 6.1e-32 109.3 26.6 8.2e-19 67.2 8.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ABA_GPCR PF12430.3 KPI39124.1 - 0.0087 15.2 1.6 1.6 7.7 0.1 2.1 1 1 1 2 2 2 2 Abscisic acid G-protein coupled receptor DUF2970 PF11174.3 KPI39124.1 - 3.6 7.2 9.8 0.52 9.9 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) AAA PF00004.24 KPI39125.1 - 1.5e-06 28.4 0.4 2.7e-05 24.3 0.3 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KPI39125.1 - 0.0017 18.0 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 KPI39125.1 - 0.0044 17.0 1.1 0.12 12.2 0.0 3.5 2 1 1 3 3 3 1 AAA ATPase domain Rad17 PF03215.10 KPI39125.1 - 0.0045 15.7 0.0 0.0088 14.7 0.0 1.5 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KPI39125.1 - 0.0071 16.4 0.3 0.061 13.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain IMS_C PF11799.3 KPI39127.1 - 0.082 12.8 0.4 0.54 10.2 0.0 2.0 2 0 0 2 2 2 0 impB/mucB/samB family C-terminal domain Glutaredoxin PF00462.19 KPI39128.1 - 0.078 12.9 0.3 0.2 11.6 0.2 1.7 1 0 0 1 1 1 0 Glutaredoxin Sec5 PF15469.1 KPI39128.1 - 0.11 12.2 0.8 0.19 11.4 0.6 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 MFS_1 PF07690.11 KPI39129.1 - 3.5e-39 134.5 48.4 4.2e-37 127.6 22.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI39129.1 - 2.6e-14 52.6 10.8 2.6e-14 52.6 7.5 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KPI39129.1 - 0.0023 16.2 4.5 0.0036 15.5 3.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 KPI39129.1 - 0.073 13.1 0.2 0.073 13.1 0.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) ThiF PF00899.16 KPI39130.1 - 2.6e-08 33.7 0.0 4.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family IFT57 PF10498.4 KPI39131.1 - 0.00012 20.9 7.5 0.16 10.6 0.0 3.0 2 1 1 3 3 3 2 Intra-flagellar transport protein 57 TPD52 PF04201.10 KPI39131.1 - 0.1 12.3 7.2 0.16 11.6 3.9 2.0 2 0 0 2 2 2 0 Tumour protein D52 family HisKA PF00512.20 KPI39131.1 - 1.7 8.7 5.8 0.3 11.1 0.5 2.5 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain V_ATPase_I PF01496.14 KPI39131.1 - 3.3 5.4 4.5 0.89 7.3 0.6 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family SAM_2 PF07647.12 KPI39133.1 - 7.7e-18 64.1 0.0 1.4e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KPI39133.1 - 8.5e-13 48.2 0.0 1.4e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KPI39133.1 - 6.6e-12 45.7 0.0 1.5e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Myb_Cef PF11831.3 KPI39134.1 - 1.5e-30 106.1 8.2 1.5e-30 106.1 5.7 4.4 3 2 1 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.1 KPI39134.1 - 5.8e-20 71.1 5.6 7.6e-14 51.5 1.5 3.6 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KPI39134.1 - 1.6e-19 69.6 4.5 5.2e-10 39.2 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Utp11 PF03998.8 KPI39136.1 - 9.9e-54 182.7 18.3 1.6e-53 182.0 12.7 1.3 1 1 0 1 1 1 1 Utp11 protein DUF4527 PF15030.1 KPI39136.1 - 0.24 10.6 10.1 0.044 13.0 4.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4527) F-box-like PF12937.2 KPI39137.1 - 0.04 13.6 0.0 0.18 11.5 0.0 2.1 2 1 0 2 2 2 0 F-box-like PI31_Prot_N PF11566.3 KPI39138.1 - 6.4e-30 103.8 0.0 8.5e-30 103.3 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 KPI39138.1 - 8.8e-15 55.1 20.2 8.8e-15 55.1 14.0 3.1 3 0 0 3 3 3 1 PI31 proteasome regulator Transglut_core PF01841.14 KPI39139.1 - 7.4e-12 45.4 0.0 1.7e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 KPI39139.1 - 0.011 15.0 0.0 0.24 10.6 0.0 2.2 1 1 0 1 1 1 0 Transglutaminase-like domain NfI_DNAbd_pre-N PF10524.4 KPI39139.1 - 0.058 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus FYVE_2 PF02318.11 KPI39140.1 - 0.058 13.2 4.2 0.1 12.5 2.9 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4 PF00097.20 KPI39140.1 - 0.48 10.1 8.2 0.86 9.3 5.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ORC6 PF05460.8 KPI39140.1 - 0.69 8.9 10.1 0.79 8.7 7.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MMR_HSR1 PF01926.18 KPI39141.1 - 1.1e-13 51.1 0.0 1.7e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KPI39141.1 - 4.5e-06 26.0 0.0 8.6e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KPI39141.1 - 0.0008 18.6 0.4 0.0022 17.2 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 KPI39141.1 - 0.0052 15.8 0.0 0.0074 15.3 0.0 1.1 1 0 0 1 1 1 1 Septin AIG1 PF04548.11 KPI39141.1 - 0.0071 15.4 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family MobB PF03205.9 KPI39141.1 - 0.0082 15.8 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KPI39141.1 - 0.016 15.4 0.0 0.054 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KPI39141.1 - 0.017 13.8 0.0 0.22 10.2 0.0 2.2 1 1 1 2 2 2 0 ArgK protein GTP_EFTU PF00009.22 KPI39141.1 - 0.018 14.4 0.0 0.66 9.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 KPI39141.1 - 0.025 15.3 0.0 0.069 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KPI39141.1 - 0.038 13.9 0.1 0.073 13.0 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.18 KPI39141.1 - 0.047 12.4 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family Dynamin_N PF00350.18 KPI39141.1 - 0.047 13.4 0.3 0.53 10.0 0.1 2.1 2 0 0 2 2 2 0 Dynamin family Arf PF00025.16 KPI39141.1 - 0.09 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_29 PF13555.1 KPI39141.1 - 0.11 12.0 0.1 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.5 KPI39141.1 - 0.11 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 KPI39141.1 - 0.12 12.8 0.1 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein DUF3902 PF13042.1 KPI39143.1 - 0.0097 15.2 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3902) Reticulon PF02453.12 KPI39143.1 - 0.025 14.1 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 Reticulon Clr5 PF14420.1 KPI39144.1 - 4.7e-16 58.4 4.2 4.7e-16 58.4 2.9 1.8 2 0 0 2 2 2 1 Clr5 domain Cupin_1 PF00190.17 KPI39145.1 - 1.1e-06 28.0 0.1 2.4e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Cupin AAA_13 PF13166.1 KPI39146.1 - 1.1 7.5 7.9 1.7 7.0 5.5 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 KPI39146.1 - 7.4 4.2 5.9 9.7 3.9 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bap31 PF05529.7 KPI39146.1 - 7.5 5.9 9.1 0.29 10.5 1.9 1.7 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Oxidored-like PF09791.4 KPI39147.1 - 2.6e-25 87.6 3.8 2.6e-25 87.6 2.6 2.1 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal Acyl-CoA_dh_1 PF00441.19 KPI39148.1 - 1.8e-32 112.5 0.4 2.5e-32 112.0 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KPI39148.1 - 6.9e-22 78.1 0.0 2.4e-21 76.4 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KPI39148.1 - 5.6e-20 70.6 0.3 9.9e-20 69.8 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KPI39148.1 - 2.4e-06 27.8 0.2 6.4e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain adh_short PF00106.20 KPI39149.1 - 1e-21 77.5 1.1 3e-21 76.0 0.8 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI39149.1 - 1.4e-18 67.5 0.3 2.3e-18 66.8 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI39149.1 - 1.4e-13 50.9 2.5 1.1e-10 41.4 0.1 2.1 1 1 1 2 2 2 2 KR domain Glyco_tran_WecB PF03808.8 KPI39149.1 - 0.0084 15.5 0.0 0.2 11.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family Shikimate_DH PF01488.15 KPI39149.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KPI39149.1 - 0.15 12.0 1.8 2 8.3 0.4 2.3 1 1 1 2 2 2 0 NADH(P)-binding PRK PF00485.13 KPI39150.1 - 1e-51 175.2 0.0 1.4e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 KPI39150.1 - 1.1e-37 129.3 0.0 1.7e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 KPI39150.1 - 4e-09 37.3 0.0 9.7e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KPI39150.1 - 6.3e-05 23.2 0.0 0.00015 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 KPI39150.1 - 0.00062 19.4 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 KPI39150.1 - 0.0016 18.3 0.0 0.0079 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KPI39150.1 - 0.0072 15.4 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin UPF0079 PF02367.12 KPI39150.1 - 0.011 15.4 0.0 0.04 13.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 KPI39150.1 - 0.036 13.7 0.2 0.38 10.4 0.0 2.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Pribosyltran PF00156.22 KPI39150.1 - 0.043 13.5 0.0 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyl transferase domain AAA PF00004.24 KPI39150.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cpn10 PF00166.16 KPI39151.1 - 6.3e-27 93.3 0.0 7.2e-27 93.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit PKD_channel PF08016.7 KPI39152.1 - 6.8e-06 24.7 20.8 0.00037 19.0 14.4 2.3 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 KPI39152.1 - 9.7e-06 24.9 19.5 2.2e-05 23.8 13.4 1.7 1 1 0 1 1 1 1 Ion transport protein DAO PF01266.19 KPI39153.1 - 1.5e-41 142.5 0.0 1.8e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KPI39153.1 - 3.2e-07 30.6 0.0 0.0078 16.3 0.0 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI39153.1 - 2.6e-06 27.4 0.0 0.0021 17.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI39153.1 - 4e-06 25.9 0.0 0.002 17.0 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KPI39153.1 - 6.5e-06 25.2 0.0 0.047 12.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 KPI39153.1 - 1.4e-05 24.9 0.0 0.0073 16.0 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KPI39153.1 - 0.00012 21.1 0.1 0.028 13.3 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.22 KPI39153.1 - 0.00062 20.1 0.0 0.083 13.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KPI39153.1 - 0.00082 18.5 0.1 0.069 12.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KPI39153.1 - 0.0023 16.4 0.0 0.56 8.6 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 KPI39153.1 - 0.0025 17.8 0.0 0.0065 16.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KPI39153.1 - 0.022 13.3 0.4 0.18 10.4 0.3 2.0 1 1 0 1 1 1 0 Tryptophan halogenase Ldh_1_N PF00056.18 KPI39153.1 - 0.03 14.1 0.0 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain TrkA_N PF02254.13 KPI39153.1 - 0.05 13.6 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 KPI39153.1 - 0.057 12.4 0.2 0.13 11.3 0.0 1.6 2 0 0 2 2 2 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 KPI39153.1 - 0.097 12.0 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KPI39153.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 KPI39153.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Mqo PF06039.10 KPI39153.1 - 0.17 10.0 0.0 0.51 8.4 0.0 1.7 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Saccharop_dh PF03435.13 KPI39153.1 - 0.17 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase AA_permease PF00324.16 KPI39154.1 - 1.2e-87 294.2 39.6 1.5e-87 293.9 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI39154.1 - 3.7e-21 75.1 44.2 5.3e-21 74.6 30.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 KPI39154.1 - 0.065 12.8 0.2 0.18 11.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) Amidase PF01425.16 KPI39155.1 - 3.3e-87 293.1 0.0 3.8e-87 292.9 0.0 1.0 1 0 0 1 1 1 1 Amidase Cupin_2 PF07883.6 KPI39156.1 - 9.9e-16 57.0 1.2 2.4e-15 55.7 0.5 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 KPI39156.1 - 7.1e-06 25.3 0.1 3.3e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 KPI39156.1 - 7.3e-06 25.7 0.2 1e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 KPI39156.1 - 0.00045 19.8 0.1 0.00056 19.5 0.1 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase CENP-C_C PF11699.3 KPI39156.1 - 0.0011 18.8 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_6 PF12852.2 KPI39156.1 - 0.002 17.7 0.3 0.009 15.6 0.1 1.8 1 1 1 2 2 2 1 Cupin Cupin_1 PF00190.17 KPI39156.1 - 0.0085 15.5 0.1 0.011 15.1 0.1 1.4 1 1 0 1 1 1 1 Cupin Auxin_BP PF02041.11 KPI39156.1 - 0.025 14.0 0.1 0.043 13.2 0.1 1.5 1 1 0 1 1 1 0 Auxin binding protein EutQ PF06249.7 KPI39156.1 - 0.069 12.6 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ TrmE_N PF10396.4 KPI39157.1 - 1.1e-33 115.6 0.0 3.6e-33 113.9 0.0 2.0 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 KPI39157.1 - 3.1e-17 62.5 0.0 8e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 KPI39157.1 - 1.4e-08 34.9 0.3 7.2e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE Dynamin_N PF00350.18 KPI39157.1 - 3.4e-06 26.9 0.0 6.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family FeoB_N PF02421.13 KPI39157.1 - 1.1e-05 24.7 0.0 2.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KPI39157.1 - 0.00077 19.9 0.0 0.0019 18.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KPI39157.1 - 0.0011 18.4 0.0 0.35 10.2 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KPI39157.1 - 0.0098 16.1 0.0 0.098 12.9 0.0 2.3 2 1 0 2 2 2 1 ABC transporter CAP PF00188.21 KPI39158.1 - 3.9e-18 66.1 3.4 7.8e-18 65.1 2.4 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Methyltransf_11 PF08241.7 KPI39159.1 - 1.4e-14 54.3 0.0 2.4e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI39159.1 - 2.2e-13 50.4 0.0 3.9e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI39159.1 - 7.2e-13 48.3 0.0 1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI39159.1 - 1.3e-12 48.0 0.0 6.1e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI39159.1 - 3.7e-12 46.2 0.0 4.5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI39159.1 - 9.3e-11 41.7 0.0 1.5e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI39159.1 - 1e-10 42.1 0.0 1.7e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI39159.1 - 1.4e-07 30.8 0.0 1.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Pox_MCEL PF03291.11 KPI39159.1 - 2.2e-07 30.0 0.0 3.4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme MTS PF05175.9 KPI39159.1 - 5.5e-07 29.1 0.0 9.2e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 KPI39159.1 - 0.025 14.2 0.0 0.054 13.1 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Bin3 PF06859.7 KPI39159.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) DUF1664 PF07889.7 KPI39160.1 - 4.1 7.2 29.3 0.023 14.4 1.6 5.0 5 2 1 6 6 6 0 Protein of unknown function (DUF1664) GHMP_kinases_N PF00288.21 KPI39162.1 - 4.4e-13 49.0 2.4 1.6e-12 47.2 1.7 1.9 1 1 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KPI39162.1 - 8.4e-05 22.6 0.0 0.00032 20.8 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal DUF4371 PF14291.1 KPI39162.1 - 0.089 12.3 0.1 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) DUF3572 PF12096.3 KPI39162.1 - 0.12 12.1 0.0 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) Methyltransf_33 PF10017.4 KPI39163.1 - 2.5e-27 95.2 0.6 2.1e-25 89.0 0.6 2.3 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 KPI39163.1 - 2.5e-10 40.1 0.1 5.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 KPI39163.1 - 1.9e-07 31.5 0.2 4.7e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.1 KPI39163.1 - 0.004 17.4 0.0 0.009 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain WD40 PF00400.27 KPI39164.1 - 1.4e-05 24.7 1.5 0.00078 19.2 0.0 3.4 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KPI39164.1 - 0.024 13.4 0.0 0.052 12.3 0.0 1.6 2 0 0 2 2 2 0 Coatomer WD associated region UvdE PF03851.9 KPI39166.1 - 1e-110 369.1 0.0 1.3e-110 368.7 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE Adeno_terminal PF02459.10 KPI39166.1 - 0.16 10.1 0.4 0.27 9.3 0.3 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein adh_short PF00106.20 KPI39167.1 - 4.7e-15 55.8 0.1 5.9e-15 55.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI39167.1 - 1.8e-07 31.1 0.0 2.3e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI39167.1 - 1.5e-05 24.7 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 KR domain AJAP1_PANP_C PF15298.1 KPI39168.1 - 2.4 7.9 17.2 0.51 10.1 5.8 2.4 2 0 0 2 2 2 0 AJAP1/PANP C-terminus DDHD PF02862.12 KPI39169.1 - 2.6e-39 135.3 7.8 3.8e-22 79.1 0.0 3.8 3 2 1 4 4 4 2 DDHD domain Abhydrolase_6 PF12697.2 KPI39169.1 - 0.0065 16.3 0.0 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI39169.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sugar_tr PF00083.19 KPI39170.1 - 1.9e-29 102.5 26.7 3.4e-19 68.7 5.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI39170.1 - 5.1e-16 58.3 37.5 1.2e-12 47.2 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.8 KPI39170.1 - 0.15 12.1 0.2 0.15 12.1 0.2 5.4 5 1 1 6 6 6 0 Transglycosylase associated protein Thr_synth_N PF14821.1 KPI39171.1 - 2e-23 82.2 0.0 4.1e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 KPI39171.1 - 2.6e-22 79.4 0.0 1.8e-21 76.7 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Acyl-CoA_dh_1 PF00441.19 KPI39172.1 - 1.1e-16 61.2 0.7 1.7e-15 57.4 0.5 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KPI39172.1 - 6.2e-06 25.6 1.4 0.00014 21.3 1.0 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF3437 PF11919.3 KPI39172.1 - 0.14 11.9 0.2 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) DUF3112 PF11309.3 KPI39174.1 - 1e-45 155.4 14.3 1e-42 145.6 1.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) DUF4149 PF13664.1 KPI39174.1 - 9.2 6.3 12.5 4.7 7.3 4.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) Gate PF07670.9 KPI39174.1 - 9.6 6.1 10.0 2.4 8.0 3.7 2.2 2 0 0 2 2 2 0 Nucleoside recognition MMS1_N PF10433.4 KPI39176.1 - 1.6e-71 240.9 0.0 8.6e-71 238.5 0.0 2.1 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KPI39176.1 - 1e-56 192.4 0.0 1.2e-51 175.7 0.0 3.7 3 1 1 4 4 4 3 CPSF A subunit region Mannosyl_trans3 PF11051.3 KPI39177.1 - 5e-37 127.7 0.0 5.8e-36 124.2 0.0 2.3 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 KPI39177.1 - 0.016 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 8 ADH_N PF08240.7 KPI39178.1 - 7.8e-31 106.0 0.6 1.3e-30 105.3 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI39178.1 - 3.8e-16 58.8 1.2 9.8e-13 47.7 0.3 2.5 1 1 1 2 2 2 2 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 KPI39178.1 - 0.018 15.0 0.3 0.031 14.3 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KPI39178.1 - 0.028 14.5 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KPI39178.1 - 0.033 14.6 0.1 0.66 10.4 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RhoGEF PF00621.15 KPI39179.1 - 6.5e-32 110.8 1.7 1.3e-31 109.8 1.1 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 KPI39179.1 - 7.8e-32 109.8 0.0 1.8e-31 108.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 KPI39179.1 - 3.8e-25 87.7 0.1 1.2e-24 86.1 0.0 2.0 2 0 0 2 2 2 1 CDC24 Calponin PB1 PF00564.19 KPI39179.1 - 1.3e-05 24.7 0.0 3.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 KPI39179.1 - 0.00059 20.0 0.7 0.0021 18.2 0.1 2.1 1 1 1 2 2 2 1 PH domain MFS_1 PF07690.11 KPI39180.1 - 1e-31 109.9 25.9 1e-31 109.9 17.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily PP2C_2 PF13672.1 KPI39181.1 - 3.8e-08 33.0 0.5 1.3e-07 31.2 0.4 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KPI39181.1 - 0.022 14.4 0.2 0.13 11.9 0.0 2.3 3 1 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 KPI39181.1 - 0.056 12.8 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein phosphatase 2C AA_permease_2 PF13520.1 KPI39182.1 - 2.4e-47 161.4 51.7 2.9e-47 161.1 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI39182.1 - 1.5e-23 82.8 41.5 2.2e-23 82.3 28.8 1.1 1 0 0 1 1 1 1 Amino acid permease SART-1 PF03343.8 KPI39183.1 - 0.023 13.0 0.0 0.032 12.6 0.0 1.1 1 0 0 1 1 1 0 SART-1 family NUDIX_2 PF13869.1 KPI39184.1 - 2e-11 43.5 0.0 2.3e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF948 PF06103.6 KPI39185.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) RNase_T PF00929.19 KPI39187.1 - 7e-13 49.1 0.0 1.1e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KPI39187.1 - 0.00018 21.0 0.0 0.00041 19.8 0.0 1.5 1 1 0 1 1 1 1 3'-5' exonuclease DUF4611 PF15387.1 KPI39187.1 - 0.074 13.1 5.2 3.2 7.9 3.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.7 KPI39187.1 - 0.53 9.4 5.7 1.1 8.4 4.0 1.5 1 0 0 1 1 1 0 NOA36 protein DUF3439 PF11921.3 KPI39187.1 - 2.8 7.7 6.1 0.57 9.9 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) CoaE PF01121.15 KPI39188.1 - 1.7e-38 131.8 0.0 2.7e-37 127.9 0.0 2.0 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 KPI39188.1 - 0.035 14.4 0.6 0.84 9.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KPI39188.1 - 0.046 14.5 0.7 0.11 13.3 0.1 1.9 2 1 0 2 2 2 0 AAA domain KOW PF00467.24 KPI39189.1 - 5.1e-07 29.1 0.5 5.1e-07 29.1 0.3 2.1 2 1 0 2 2 2 1 KOW motif GTP_EFTU_D2 PF03144.20 KPI39189.1 - 0.1 12.6 3.7 1.2 9.2 0.2 2.4 1 1 0 2 2 2 0 Elongation factor Tu domain 2 Phage_1_1 PF08200.6 KPI39189.1 - 4.9 7.4 7.3 1.1 9.5 2.2 2.1 2 0 0 2 2 2 0 Bacteriophage 1.1 Protein TP2 PF01254.13 KPI39189.1 - 8.7 6.6 8.4 1.2 9.5 2.2 1.8 1 1 1 2 2 2 0 Nuclear transition protein 2 Glyco_transf_15 PF01793.11 KPI39190.1 - 1.8e-133 444.5 5.7 2.2e-133 444.3 4.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Rad60-SLD_2 PF13881.1 KPI39191.1 - 5.6e-12 45.5 0.0 1.2e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KPI39191.1 - 7.8e-05 21.9 0.0 0.00018 20.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KPI39191.1 - 0.0003 20.9 0.0 0.00057 20.0 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ceramidase PF05875.7 KPI39194.1 - 5.9e-97 323.9 14.3 6.9e-97 323.6 9.9 1.0 1 0 0 1 1 1 1 Ceramidase Beta-lactamase PF00144.19 KPI39196.1 - 2.8e-35 121.9 0.5 7.1e-35 120.5 0.3 1.5 1 1 0 1 1 1 1 Beta-lactamase ARID PF01388.16 KPI39196.1 - 0.17 11.7 0.0 6.5 6.6 0.0 2.2 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain WD40 PF00400.27 KPI39197.1 - 2.2e-25 87.5 18.8 5.5e-08 32.3 0.3 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat GLYCAM-1 PF05242.6 KPI39197.1 - 0.14 12.1 3.3 0.13 12.1 0.4 2.3 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Ribonuclease_3 PF00636.21 KPI39198.1 - 7.3e-30 103.7 0.0 1.6e-13 51.0 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KPI39198.1 - 3.9e-19 68.8 0.0 1.9e-08 34.3 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.26 KPI39198.1 - 4.2e-16 58.5 0.1 9.1e-16 57.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KPI39198.1 - 3e-10 39.8 0.0 5.5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KPI39198.1 - 4.2e-10 39.7 0.0 9.4e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Dicer_dimer PF03368.9 KPI39198.1 - 4.6e-10 39.1 0.0 1.6e-08 34.1 0.0 2.6 2 0 0 2 2 2 1 Dicer dimerisation domain SNF2_N PF00176.18 KPI39198.1 - 0.0045 15.8 0.1 0.015 14.1 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 KPI39199.1 - 2.3e-09 36.9 9.2 3.7e-09 36.2 6.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KPI39199.1 - 1.1e-08 34.8 6.1 2.9e-08 33.5 4.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KPI39199.1 - 3.4e-08 33.2 4.0 6.4e-07 29.1 3.5 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KPI39199.1 - 5e-08 32.4 7.2 8.2e-08 31.8 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI39199.1 - 1.7e-07 30.8 8.5 3e-07 30.0 5.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KPI39199.1 - 2.7e-07 30.1 5.2 2.7e-06 26.9 4.0 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KPI39199.1 - 4.7e-05 23.0 5.7 0.00015 21.4 1.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 KPI39199.1 - 0.0083 15.8 3.0 0.23 11.2 1.0 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KPI39199.1 - 0.055 13.5 3.7 0.12 12.4 2.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 KPI39199.1 - 0.055 13.2 5.8 0.21 11.4 4.1 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KPI39199.1 - 0.068 12.7 4.7 0.18 11.4 3.3 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 KPI39199.1 - 0.12 11.9 4.7 0.22 11.0 3.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Tmpp129 PF10272.4 KPI39199.1 - 0.31 9.7 4.5 0.48 9.0 3.1 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor FYVE PF01363.16 KPI39199.1 - 0.85 9.5 6.4 2.4 8.1 4.4 1.8 1 0 0 1 1 1 0 FYVE zinc finger Prok-RING_4 PF14447.1 KPI39199.1 - 1.8 8.1 6.4 1.2 8.7 1.8 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 TerY-C PF15616.1 KPI39199.1 - 1.8 8.4 5.8 33 4.3 4.1 2.3 1 1 0 1 1 1 0 TerY-C metal binding domain FANCL_C PF11793.3 KPI39199.1 - 4 7.4 6.6 16 5.5 4.6 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Atg14 PF10186.4 KPI39199.1 - 7.6 5.3 21.5 0.42 9.5 2.8 2.4 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Arginase PF00491.16 KPI39201.1 - 2.8e-86 289.2 0.0 3.3e-86 289.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KPI39201.1 - 0.075 13.2 0.0 0.16 12.1 0.0 1.6 1 1 1 2 2 2 0 UPF0489 domain Peroxidase_2 PF01328.12 KPI39203.1 - 7.1e-10 38.0 0.7 1.7e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Peroxidase, family 2 MOZ_SAS PF01853.13 KPI39204.1 - 4.1e-79 264.2 0.1 4.2e-76 254.4 0.0 2.2 2 0 0 2 2 2 2 MOZ/SAS family Tudor-knot PF11717.3 KPI39204.1 - 2e-22 78.6 0.0 5.1e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 KPI39204.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family F-box PF00646.28 KPI39205.1 - 0.0033 17.0 0.3 0.093 12.4 0.0 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KPI39205.1 - 0.0097 15.6 1.1 0.022 14.4 0.0 2.2 3 0 0 3 3 3 1 F-box-like PRANC PF09372.5 KPI39205.1 - 0.017 15.0 1.4 0.093 12.7 0.1 2.5 2 1 1 3 3 3 0 PRANC domain DnaJ PF00226.26 KPI39206.1 - 2.3e-15 56.0 0.8 3.4e-15 55.5 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain Doppel PF11466.3 KPI39207.1 - 0.051 13.1 1.9 0.091 12.3 1.3 1.4 1 0 0 1 1 1 0 Prion-like protein Doppel COesterase PF00135.23 KPI39208.1 - 8.9e-78 262.2 0.7 7.6e-72 242.7 0.3 2.7 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI39208.1 - 0.00035 20.2 0.0 0.00069 19.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold GFA PF04828.9 KPI39208.1 - 0.0031 17.4 0.0 0.0069 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF2235 PF09994.4 KPI39209.1 - 9.8e-73 244.9 0.0 1.5e-72 244.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KPI39209.1 - 0.025 14.3 0.0 0.13 11.9 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI39210.1 - 1.3e-24 87.4 0.0 1.5e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI39210.1 - 5.5e-22 78.4 0.0 7.6e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI39210.1 - 7.8e-13 48.4 0.0 4e-12 46.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KPI39210.1 - 0.00024 20.6 0.1 0.038 13.4 0.1 2.8 1 1 2 3 3 3 1 Phospholipase/Carboxylesterase Ndr PF03096.9 KPI39210.1 - 0.011 14.1 0.0 0.12 10.8 0.0 2.0 1 1 0 1 1 1 0 Ndr family Peptidase_S15 PF02129.13 KPI39210.1 - 0.032 13.6 0.0 0.062 12.7 0.0 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 KPI39210.1 - 0.064 12.8 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.6 KPI39210.1 - 0.079 12.6 0.0 3.4 7.3 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 KPI39210.1 - 0.13 11.5 0.1 7.4 5.7 0.0 2.3 2 1 0 2 2 2 0 Prolyl oligopeptidase family IL32 PF15225.1 KPI39211.1 - 0.06 13.2 0.1 0.15 12.0 0.0 1.6 2 0 0 2 2 2 0 Interleukin 32 MFS_1 PF07690.11 KPI39212.1 - 1.9e-08 33.4 51.3 5.1e-07 28.7 35.0 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily PEX11 PF05648.9 KPI39213.1 - 2e-52 177.6 0.5 2.4e-52 177.4 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Fungal_trans PF04082.13 KPI39215.1 - 2.4e-26 92.1 0.0 5.4e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_15 PF13429.1 KPI39215.1 - 0.15 11.1 2.5 0.087 11.8 0.3 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_pol_lambd_f PF10391.4 KPI39217.1 - 1.2e-19 69.5 0.7 2.4e-19 68.6 0.5 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 KPI39217.1 - 5.7e-17 61.1 0.1 1.4e-16 59.9 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 KPI39217.1 - 3.3e-15 56.1 0.0 8.9e-15 54.7 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 KPI39217.1 - 3.1e-06 27.2 0.0 7.2e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain FAD_binding_3 PF01494.14 KPI39218.1 - 4.4e-19 68.7 0.0 7e-19 68.0 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI39218.1 - 1e-09 37.7 0.5 0.00023 20.1 0.6 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI39218.1 - 2.8e-06 26.4 0.4 4.4e-06 25.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KPI39218.1 - 6.7e-06 26.0 0.5 2.8e-05 24.0 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KPI39218.1 - 9.6e-05 21.0 0.1 0.00031 19.3 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 KPI39218.1 - 0.00036 20.8 0.1 0.018 15.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI39218.1 - 0.00041 20.2 0.0 0.0014 18.5 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KPI39218.1 - 0.0017 17.5 0.3 0.0025 16.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KPI39218.1 - 0.0017 17.3 0.2 0.0029 16.5 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KPI39218.1 - 0.0017 17.4 0.1 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 KPI39218.1 - 0.0031 16.1 0.1 0.0073 14.9 0.0 1.6 1 1 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 KPI39218.1 - 0.007 16.4 0.0 0.015 15.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KPI39218.1 - 0.01 14.6 0.0 0.024 13.4 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase AlaDh_PNT_C PF01262.16 KPI39218.1 - 0.07 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SnoaL_2 PF12680.2 KPI39220.1 - 9.7e-05 22.7 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 KPI39220.1 - 0.11 12.1 0.1 0.34 10.4 0.1 1.9 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Germane PF10646.4 KPI39220.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Sporulation and spore germination GTP_EFTU PF00009.22 KPI39221.1 - 6e-12 45.3 0.0 9.9e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KPI39221.1 - 0.098 12.2 0.2 0.33 10.5 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KPI39221.1 - 0.14 11.3 0.1 0.32 10.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 KPI39221.1 - 0.15 12.5 0.3 0.79 10.2 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein CTD_bind PF04818.8 KPI39222.1 - 3.4e-19 68.8 0.0 8.8e-19 67.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Fungal_trans_2 PF11951.3 KPI39223.1 - 1.7e-12 46.6 2.2 1.7e-12 46.6 1.5 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain F-box PF00646.28 KPI39224.1 - 4.7e-06 26.1 0.1 1.2e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KPI39224.1 - 9.9e-05 21.9 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like Peptidase_M19 PF01244.16 KPI39225.1 - 3.6e-104 348.1 0.0 6.1e-104 347.3 0.0 1.3 1 1 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF2274 PF10038.4 KPI39227.1 - 0.035 14.2 0.1 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) DUF500 PF04366.7 KPI39228.1 - 2e-43 146.8 0.3 3.3e-43 146.1 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 KPI39228.1 - 2.3e-15 55.7 0.3 7.2e-15 54.1 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KPI39228.1 - 1.7e-14 53.0 0.2 6.8e-14 51.0 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KPI39228.1 - 2.3e-12 46.3 0.0 3.9e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Gal_mutarotas_2 PF13802.1 KPI39228.1 - 0.21 11.4 1.7 1.8 8.4 0.0 2.7 3 0 0 3 3 3 0 Galactose mutarotase-like Acylphosphatase PF00708.13 KPI39229.1 - 2.6e-27 94.7 0.3 2.9e-27 94.6 0.2 1.0 1 0 0 1 1 1 1 Acylphosphatase DLH PF01738.13 KPI39231.1 - 2.6e-16 59.5 0.0 1.7e-07 30.7 0.0 3.0 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KPI39231.1 - 6.7e-05 22.6 0.0 0.0024 17.6 0.0 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KPI39231.1 - 0.1 12.0 0.0 3.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase NAD_binding_1 PF00175.16 KPI39232.1 - 8.4e-13 48.8 0.0 1.3e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF2040 PF09745.4 KPI39233.1 - 1.2e-36 125.3 12.1 1.2e-36 125.3 8.4 3.5 4 0 0 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) L31 PF09784.4 KPI39233.1 - 9.6 6.3 9.6 0.32 11.0 1.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 adh_short PF00106.20 KPI39234.1 - 3.4e-19 69.3 1.5 9.3e-11 41.9 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KPI39234.1 - 7.8e-15 55.3 0.3 2.8e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI39234.1 - 2.1e-06 27.5 1.8 0.0002 21.0 0.1 2.2 1 1 1 2 2 2 2 KR domain Epimerase PF01370.16 KPI39234.1 - 2.7e-06 27.0 1.1 4e-05 23.1 0.8 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KPI39234.1 - 0.00085 18.2 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KPI39234.1 - 0.0072 16.3 0.2 0.61 10.0 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 KPI39235.1 - 5.5e-15 55.6 0.6 2e-13 50.6 0.4 2.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI39235.1 - 0.0065 16.1 0.1 0.059 13.0 0.0 2.2 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 KPI39235.1 - 0.015 15.0 0.1 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase BcrAD_BadFG PF01869.15 KPI39237.1 - 2e-16 60.1 1.0 4.1e-16 59.0 0.1 1.9 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.1 KPI39237.1 - 7.6e-08 32.1 0.1 2.7e-07 30.3 0.0 2.0 1 0 0 1 1 1 1 SIS domain SIS PF01380.17 KPI39237.1 - 9.2e-07 28.5 1.3 3.2e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 SIS domain DUF281 PF03436.8 KPI39237.1 - 2.2 8.4 6.5 0.33 11.0 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF281) ParA PF10609.4 KPI39238.1 - 2.6e-32 110.5 0.2 4.7e-32 109.7 0.2 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KPI39238.1 - 8.1e-14 51.4 0.0 1.4e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KPI39238.1 - 1.8e-08 34.4 0.3 1.3e-07 31.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain MipZ PF09140.6 KPI39238.1 - 0.00029 20.0 0.0 0.00058 19.0 0.0 1.5 1 0 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 KPI39238.1 - 0.0018 17.6 0.0 0.0049 16.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 KPI39238.1 - 0.0032 16.5 0.2 0.056 12.4 0.1 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase Nucleoside_tran PF01733.13 KPI39240.1 - 1.1e-29 103.5 8.1 1.3e-29 103.3 5.6 1.0 1 0 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.11 KPI39240.1 - 0.0034 16.1 18.6 0.0082 14.9 8.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DWNN PF08783.6 KPI39241.1 - 7.8e-26 89.8 0.4 3.6e-25 87.6 0.0 2.3 2 0 0 2 2 2 1 DWNN domain U-box PF04564.10 KPI39241.1 - 2e-07 30.8 0.0 7.2e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-CCHC_2 PF13696.1 KPI39241.1 - 0.00019 20.8 3.3 0.0005 19.5 2.3 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KPI39241.1 - 0.00043 20.0 2.5 0.00093 19.0 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Med3 PF11593.3 KPI39241.1 - 0.003 16.8 37.9 0.0057 15.9 26.3 1.4 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal zf-C3HC4_2 PF13923.1 KPI39241.1 - 0.0049 16.8 7.2 0.0049 16.8 5.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.1 KPI39241.1 - 0.016 14.9 0.3 0.034 13.8 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-C3HC4_4 PF15227.1 KPI39241.1 - 0.052 13.4 8.7 0.12 12.2 6.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KPI39241.1 - 0.06 12.8 3.1 0.19 11.2 2.2 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 KPI39241.1 - 0.11 12.1 7.0 0.27 10.9 4.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KPI39241.1 - 0.14 11.7 5.2 0.34 10.5 3.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 KPI39241.1 - 1.4 8.6 9.4 1.1 9.0 3.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI39241.1 - 4.1 7.2 12.2 0.37 10.5 4.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.1 KPI39241.1 - 4.9 7.0 13.4 0.07 12.9 4.1 1.8 2 0 0 2 2 2 0 Ring finger domain Ank_2 PF12796.2 KPI39242.1 - 2e-44 149.8 33.7 2.9e-08 33.9 0.0 13.0 8 5 2 11 11 11 10 Ankyrin repeats (3 copies) Ank PF00023.25 KPI39242.1 - 1.7e-23 81.1 22.5 0.16 11.8 0.0 17.0 18 0 0 18 18 18 8 Ankyrin repeat Ank_4 PF13637.1 KPI39242.1 - 3.9e-23 81.3 19.1 0.001 19.5 0.0 13.6 11 2 2 13 13 13 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI39242.1 - 1.7e-13 49.3 16.4 4.8 7.7 0.0 16.5 18 1 1 19 19 19 2 Ankyrin repeat Ank_5 PF13857.1 KPI39242.1 - 7e-10 38.8 14.2 0.0017 18.5 0.0 11.3 11 1 2 13 13 13 3 Ankyrin repeats (many copies) Coagulin PF02035.10 KPI39242.1 - 0.18 11.4 0.5 0.38 10.3 0.4 1.5 1 0 0 1 1 1 0 Coagulin FAM104 PF15434.1 KPI39243.1 - 0.27 11.4 3.4 0.35 11.1 2.3 1.2 1 0 0 1 1 1 0 Family 104 Pkinase_C PF00433.19 KPI39244.1 - 4.5 7.8 9.1 66 4.1 6.3 2.6 1 1 0 1 1 1 0 Protein kinase C terminal domain MFS_1 PF07690.11 KPI39245.1 - 2e-10 39.9 40.5 8e-10 37.9 27.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KPI39245.1 - 1.5e-06 27.8 4.7 1.5e-06 27.8 3.3 2.9 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KPI39246.1 - 1.7e-29 102.6 35.8 2.2e-29 102.3 23.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Transp_cyt_pur PF02133.10 KPI39247.1 - 1.5e-94 317.0 34.6 1.7e-94 316.8 24.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CoA_transf_3 PF02515.12 KPI39248.1 - 9.9e-32 109.7 0.0 2.5e-28 98.6 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III RNA_pol_3_Rpc31 PF11705.3 KPI39249.1 - 0.1 12.5 7.0 0.13 12.2 4.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Hep_59 PF07052.6 KPI39250.1 - 6.6e-09 36.0 0.2 1.3e-07 31.8 0.0 2.4 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 DUF3591 PF12157.3 KPI39251.1 - 7.1e-152 505.9 9.3 1.5e-109 366.4 3.7 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3591) zinc_ribbon_2 PF13240.1 KPI39251.1 - 0.0062 15.9 2.9 1.3 8.6 0.2 2.4 2 0 0 2 2 2 2 zinc-ribbon domain zf-CCHC PF00098.18 KPI39251.1 - 0.014 15.2 0.9 0.028 14.3 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-ribbon_3 PF13248.1 KPI39251.1 - 0.07 12.3 4.2 0.25 10.6 3.0 1.9 1 1 1 2 2 2 0 zinc-ribbon domain ADK_lid PF05191.9 KPI39251.1 - 0.87 9.2 3.1 2.4 7.9 1.3 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-CCHC_6 PF15288.1 KPI39251.1 - 8.9 6.0 8.3 0.46 10.1 1.4 2.0 2 0 0 2 2 2 0 Zinc knuckle TPT PF03151.11 KPI39252.1 - 1.1e-31 109.5 13.0 1.1e-31 109.5 9.0 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KPI39252.1 - 7e-06 26.1 33.6 0.0028 17.6 6.7 2.7 3 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 KPI39252.1 - 0.00025 20.0 22.4 0.00035 19.5 15.5 1.3 1 0 0 1 1 1 1 UAA transporter family Aldo_ket_red PF00248.16 KPI39253.1 - 5.5e-49 166.4 0.0 6.7e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PTR2 PF00854.16 KPI39255.1 - 8e-45 153.2 13.9 4.1e-44 150.8 9.6 1.9 1 1 0 1 1 1 1 POT family PEPCK_ATP PF01293.15 KPI39256.1 - 1.5e-186 620.4 0.0 6.4e-161 536.0 0.0 2.1 1 1 1 2 2 2 2 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 KPI39256.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arrestin_C PF02752.17 KPI39257.1 - 1e-14 54.7 0.0 6.6e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KPI39257.1 - 5.8e-14 52.1 0.0 1.4e-13 50.8 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KPI39257.1 - 0.042 13.3 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like Rad4 PF03835.10 KPI39258.1 - 2e-33 114.8 0.2 6.7e-33 113.1 0.0 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KPI39258.1 - 2.4e-24 84.8 0.2 4.8e-24 83.8 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KPI39258.1 - 1.4e-19 69.3 0.2 3e-19 68.2 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KPI39258.1 - 6.7e-13 48.7 3.3 2.3e-12 47.0 0.2 2.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KPI39258.1 - 0.0015 18.7 0.0 0.0037 17.4 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily 6PGD PF00393.14 KPI39261.1 - 9.8e-133 441.8 0.0 1.3e-132 441.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KPI39261.1 - 6.1e-51 172.4 0.0 9.2e-51 171.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KPI39261.1 - 0.11 12.6 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase MCM PF00493.18 KPI39263.1 - 2.1e-139 463.9 0.0 3e-139 463.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KPI39263.1 - 6.5e-21 75.0 0.0 2.7e-20 73.0 0.0 2.1 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 KPI39263.1 - 5.9e-06 25.5 0.0 0.00018 20.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KPI39263.1 - 1.2e-05 25.0 0.0 4.4e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KPI39263.1 - 0.0017 17.9 0.0 0.0046 16.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2797 PF10977.3 KPI39263.1 - 0.055 13.1 0.5 0.13 11.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) AAA_32 PF13654.1 KPI39263.1 - 0.18 10.3 3.6 0.099 11.2 0.2 1.9 2 0 0 2 2 2 0 AAA domain AMP-binding PF00501.23 KPI39264.1 - 6e-96 321.3 0.0 7.1e-96 321.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI39264.1 - 2.4e-13 50.8 0.1 4.4e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1368 PF07112.6 KPI39264.1 - 0.16 10.4 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) MBOAT PF03062.14 KPI39265.1 - 5.2e-20 71.8 17.3 1e-19 70.8 12.0 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KPI39265.1 - 6.6e-05 22.9 5.8 0.00027 20.9 4.0 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family NYD-SP28_assoc PF14775.1 KPI39267.1 - 0.044 13.4 0.9 0.15 11.7 0.6 1.9 1 0 0 1 1 1 0 Sperm tail C-terminal domain AA_permease PF00324.16 KPI39268.1 - 1.8e-83 280.4 38.3 1.3e-82 277.6 26.5 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI39268.1 - 9.4e-14 50.7 46.3 1.6e-12 46.7 32.1 2.3 1 1 0 1 1 1 1 Amino acid permease adh_short PF00106.20 KPI39270.1 - 1.8e-09 37.7 3.5 2.9e-08 33.8 2.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.5 KPI39270.1 - 8.4e-08 31.6 0.0 1.5e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.1 KPI39270.1 - 0.0018 18.1 0.0 0.0059 16.3 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI39270.1 - 0.0022 17.7 0.7 0.0044 16.6 0.5 1.4 1 0 0 1 1 1 1 KR domain DUF1161 PF06649.7 KPI39270.1 - 0.063 13.2 0.4 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1161) AA_permease PF00324.16 KPI39271.1 - 2e-92 310.0 50.5 8.6e-92 307.9 35.0 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI39271.1 - 7.4e-16 57.7 49.9 1e-15 57.2 34.6 1.2 1 0 0 1 1 1 1 Amino acid permease Lectin_leg-like PF03388.8 KPI39273.1 - 2.2e-62 210.1 0.0 2.8e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 KPI39273.1 - 0.004 16.5 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain UQ_con PF00179.21 KPI39274.1 - 4.8e-19 68.1 0.1 5.1e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_E PF14462.1 KPI39274.1 - 0.14 11.7 0.1 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family E FAD_binding_1 PF00667.15 KPI39275.1 - 2.3e-36 125.3 0.0 1e-20 74.1 0.0 2.4 1 1 1 2 2 2 2 FAD binding domain DLH PF01738.13 KPI39276.1 - 9.6e-14 51.1 0.0 5e-13 48.8 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KPI39276.1 - 9.7e-06 25.3 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI39276.1 - 0.11 11.7 0.1 0.52 9.4 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Fungal_trans PF04082.13 KPI39277.1 - 7.2e-12 44.7 0.2 1.2e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI39277.1 - 6.6e-10 38.7 9.9 1.2e-09 37.8 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyt-b5 PF00173.23 KPI39278.1 - 5.1e-23 80.6 0.1 6.7e-23 80.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FKBP_C PF00254.23 KPI39279.1 - 8.2e-26 89.8 0.0 2.8e-25 88.1 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF572 PF04502.8 KPI39279.1 - 0.4 9.8 20.3 0.046 12.9 6.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Zip PF02535.17 KPI39280.1 - 1.5e-15 57.0 4.9 7.6e-08 31.7 0.3 2.5 2 1 0 2 2 2 2 ZIP Zinc transporter DUF3649 PF12365.3 KPI39280.1 - 0.24 10.9 0.2 0.24 10.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) Smr PF01713.16 KPI39281.1 - 2e-08 34.2 0.0 1.5e-07 31.5 0.0 2.3 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.5 KPI39281.1 - 3.2e-06 27.0 8.4 3.2e-06 27.0 5.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) CUE PF02845.11 KPI39281.1 - 1.9e-05 24.0 0.3 0.041 13.3 0.0 3.1 3 0 0 3 3 3 2 CUE domain Nucleoside_tran PF01733.13 KPI39282.1 - 4.1e-15 55.7 1.3 6.7e-15 55.0 0.7 1.5 1 1 0 1 1 1 1 Nucleoside transporter KAR9 PF08580.5 KPI39283.1 - 2.6e-94 316.8 3.1 3.4e-94 316.4 2.1 1.1 1 0 0 1 1 1 1 Yeast cortical protein KAR9 Perilipin PF03036.11 KPI39283.1 - 0.014 14.2 0.4 0.014 14.2 0.3 2.4 2 1 0 2 2 2 0 Perilipin family DASH_Dam1 PF08653.5 KPI39283.1 - 0.28 10.9 2.1 10 5.9 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 Val_tRNA-synt_C PF10458.4 KPI39283.1 - 2 8.5 7.9 0.22 11.6 0.8 2.7 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm DUF4332 PF14229.1 KPI39283.1 - 3.2 7.7 9.1 15 5.5 0.5 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4332) GrpE PF01025.14 KPI39283.1 - 6.3 6.3 14.3 4.1 6.9 0.7 3.2 2 2 0 2 2 2 0 GrpE NAD_binding_10 PF13460.1 KPI39284.1 - 9.7e-12 45.2 0.0 1.4e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KPI39284.1 - 0.00025 20.0 0.0 0.2 10.5 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.16 KPI39284.1 - 0.00039 19.9 0.0 0.00095 18.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KPI39284.1 - 0.0025 17.1 0.1 0.067 12.4 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 KPI39284.1 - 0.0049 16.5 0.0 0.18 11.4 0.0 2.2 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 KPI39284.1 - 0.011 14.6 0.5 0.58 9.0 0.1 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein adh_short PF00106.20 KPI39284.1 - 0.025 14.4 0.6 0.62 9.9 0.0 2.4 2 1 0 2 2 2 0 short chain dehydrogenase HIM1 PF08732.5 KPI39284.1 - 0.026 12.9 0.0 0.035 12.5 0.0 1.2 1 0 0 1 1 1 0 HIM1 DUF917 PF06032.7 KPI39285.1 - 7.9e-111 370.0 0.0 1.6e-110 369.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 KPI39285.1 - 1.9e-32 112.5 2.6 1.2e-15 57.4 0.2 3.7 2 1 1 3 3 3 3 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KPI39285.1 - 8.8e-27 93.7 0.1 2.5e-26 92.2 0.0 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 KPI39285.1 - 0.0016 17.7 0.3 0.018 14.3 0.2 2.4 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Peripla_BP_3 PF13377.1 KPI39285.1 - 0.025 14.6 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein-like domain RE_HindVP PF09519.5 KPI39285.1 - 0.07 12.0 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 HindVP restriction endonuclease Glyco_hydro_cc PF11790.3 KPI39286.1 - 1.5e-49 168.6 0.0 1.9e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF2628 PF10947.3 KPI39287.1 - 0.0044 16.7 0.4 0.0061 16.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2628) ILVD_EDD PF00920.16 KPI39288.1 - 6.1e-157 523.1 0.1 7e-157 522.9 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Amidohydro_1 PF01979.15 KPI39289.1 - 8.7e-20 71.6 0.0 1.2e-19 71.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KPI39289.1 - 1.2e-13 50.6 0.0 3.5e-13 49.1 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KPI39289.1 - 1.5e-08 34.3 0.2 1.9e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KPI39289.1 - 2.1e-08 34.5 0.1 0.0026 17.8 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase TonB_dep_Rec PF00593.19 KPI39290.1 - 0.064 13.1 2.3 0.11 12.3 1.6 1.4 1 0 0 1 1 1 0 TonB dependent receptor DUF3605 PF12239.3 KPI39291.1 - 2.4e-57 193.2 0.0 2.9e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Actin PF00022.14 KPI39292.1 - 1.9e-129 431.5 0.0 2.1e-129 431.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KPI39292.1 - 7.4e-05 21.4 0.1 0.17 10.4 0.0 3.0 2 1 0 3 3 3 3 MreB/Mbl protein SGL PF08450.7 KPI39293.1 - 5.7e-13 48.8 0.0 1.2e-12 47.7 0.0 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 KPI39293.1 - 0.19 11.7 1.4 3.1 7.9 0.2 3.1 2 0 0 2 2 2 0 NHL repeat Ank_2 PF12796.2 KPI39294.1 - 1.6e-50 169.3 0.0 6.4e-12 45.6 0.0 9.2 7 2 1 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KPI39294.1 - 1.1e-36 122.7 8.1 4.7e-06 26.1 0.0 10.4 12 0 0 12 12 12 7 Ankyrin repeat Ank_4 PF13637.1 KPI39294.1 - 8e-35 118.6 0.2 3.7e-05 24.1 0.0 11.6 9 3 3 12 12 12 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI39294.1 - 2.2e-33 110.9 0.2 0.00013 21.8 0.0 11.7 12 0 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.1 KPI39294.1 - 9.6e-26 89.2 1.5 0.00029 20.9 0.1 9.9 8 1 2 10 10 10 6 Ankyrin repeats (many copies) Sugar_tr PF00083.19 KPI39295.1 - 1e-88 297.9 27.4 1.2e-88 297.7 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI39295.1 - 2.4e-18 65.9 44.4 1.5e-14 53.5 10.7 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily HeLo PF14479.1 KPI39296.1 - 0.13 11.9 4.7 0.42 10.3 0.0 2.7 2 1 1 3 3 3 0 Prion-inhibition and propagation tRNA-synt_1d PF00750.14 KPI39297.1 - 9.3e-28 97.0 0.3 3.6e-18 65.4 0.1 2.0 2 0 0 2 2 2 2 tRNA synthetases class I (R) ATG13 PF10033.4 KPI39298.1 - 1.2e-58 198.3 0.0 2.5e-58 197.2 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 13 ICMT PF04140.9 KPI39299.1 - 2e-29 101.6 1.1 3.6e-29 100.7 0.7 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KPI39299.1 - 1.3e-16 60.5 2.3 1.3e-16 60.5 1.6 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.6 KPI39299.1 - 0.00075 18.9 0.1 0.0015 17.9 0.1 1.5 1 0 0 1 1 1 1 NnrU protein DUF1295 PF06966.7 KPI39299.1 - 0.021 14.1 0.2 0.031 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 KPI39299.1 - 0.051 12.1 3.4 0.09 11.2 2.4 1.3 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family adh_short PF00106.20 KPI39301.1 - 7.6e-09 35.6 0.1 0.0025 17.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KPI39301.1 - 0.00013 21.8 0.0 0.0052 16.5 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ins_P5_2-kin PF06090.7 KPI39302.1 - 1.8e-35 122.5 0.0 1.8e-34 119.2 0.0 2.0 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Sedlin_N PF04628.8 KPI39303.1 - 1.5e-20 73.4 0.0 2.1e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Cas_Csd1 PF09709.5 KPI39303.1 - 0.0056 15.0 0.0 0.008 14.5 0.0 1.2 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csd1) Med20 PF08612.6 KPI39304.1 - 1e-11 44.4 0.0 1.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Atx10homo_assoc PF09759.4 KPI39305.1 - 9.2e-26 89.5 0.3 8e-25 86.5 0.0 2.5 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain SSXRD PF09514.5 KPI39305.1 - 2.2 7.6 5.8 5.2 6.4 4.0 1.6 1 0 0 1 1 1 0 SSXRD motif SDA1 PF05285.7 KPI39305.1 - 3.1 6.9 10.7 5.4 6.1 7.4 1.3 1 0 0 1 1 1 0 SDA1 Abhydrolase_3 PF07859.8 KPI39306.1 - 4.7e-15 55.7 0.0 1.1e-12 48.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI39306.1 - 5.7e-12 45.3 0.0 4.1e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KPI39306.1 - 1.1e-09 38.2 0.0 1.7e-09 37.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI39306.1 - 1.1e-08 35.1 0.0 1.4e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KPI39306.1 - 2.7e-08 33.0 0.2 9.7e-08 31.1 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.11 KPI39306.1 - 4.1e-05 23.1 0.0 0.11 11.9 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase AXE1 PF05448.7 KPI39306.1 - 0.0065 15.0 0.0 1.2 7.5 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Esterase PF00756.15 KPI39306.1 - 0.014 14.7 0.2 0.68 9.3 0.1 2.2 2 0 0 2 2 2 0 Putative esterase Esterase_phd PF10503.4 KPI39306.1 - 0.044 13.0 0.2 12 5.0 0.1 2.7 3 0 0 3 3 3 0 Esterase PHB depolymerase KH_dom-like PF14714.1 KPI39306.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Hat1_N PF10394.4 KPI39307.1 - 4.6e-34 117.8 0.0 8.4e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 KPI39307.1 - 0.0025 17.9 0.0 0.0072 16.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KPI39307.1 - 0.042 13.8 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family WD40 PF00400.27 KPI39309.1 - 2.8e-36 122.0 10.7 7.3e-10 38.3 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat IKI3 PF04762.7 KPI39309.1 - 0.029 12.1 0.0 2.9 5.5 0.0 2.2 1 1 1 2 2 2 0 IKI3 family Nup160 PF11715.3 KPI39309.1 - 0.13 10.3 1.6 5.8 4.9 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PAT1 PF09770.4 KPI39310.1 - 8.3 4.5 28.6 10 4.2 19.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-Tim10_DDP PF02953.10 KPI39311.1 - 1e-19 69.5 0.4 1.3e-19 69.2 0.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger MSP1a PF11670.3 KPI39311.1 - 0.033 13.9 0.9 0.053 13.3 0.6 1.3 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Tmemb_170 PF10190.4 KPI39312.1 - 0.0015 18.5 0.4 0.0015 18.5 0.3 2.1 2 0 0 2 2 2 1 Putative transmembrane protein 170 RNA_pol_Rpb2_6 PF00562.23 KPI39313.1 - 1.5e-95 320.2 0.0 1.3e-66 224.9 0.0 2.2 1 1 1 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KPI39313.1 - 3.8e-34 117.4 0.0 5.3e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 KPI39313.1 - 6.7e-24 83.4 0.0 1.7e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 KPI39313.1 - 1.6e-21 76.5 0.0 2.6e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 KPI39313.1 - 4.8e-21 74.4 0.0 1e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 KPI39313.1 - 2.5e-15 56.4 0.1 7.3e-15 54.9 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KPI39313.1 - 1.7e-06 27.9 0.0 3.7e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Cpn60_TCP1 PF00118.19 KPI39314.1 - 4.4e-143 477.4 2.9 5e-143 477.2 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.16 KPI39314.1 - 0.051 13.4 0.2 2.1 8.1 0.0 2.6 2 0 0 2 2 2 0 Resolvase, N terminal domain Acyltransferase PF01553.16 KPI39316.1 - 1e-12 47.6 0.0 2.7e-12 46.2 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase CTK3 PF12243.3 KPI39317.1 - 4.3e-41 139.8 0.0 6.9e-41 139.1 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 KPI39317.1 - 2.6e-14 52.9 8.8 7.2e-14 51.5 6.1 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Phlebovirus_NSM PF07246.6 KPI39317.1 - 0.24 10.5 0.1 0.24 10.5 0.0 2.1 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Methyltransf_23 PF13489.1 KPI39318.1 - 4.7e-23 81.6 0.0 8.4e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI39318.1 - 7.5e-12 45.0 0.0 2.9e-11 43.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI39318.1 - 2.5e-11 43.8 0.0 5.8e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI39318.1 - 3.3e-10 40.5 0.0 1.9e-09 38.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI39318.1 - 1.2e-09 38.5 0.0 4.7e-09 36.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI39318.1 - 3.3e-07 30.5 0.0 9.9e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI39318.1 - 2.4e-05 23.5 0.0 0.00012 21.3 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KPI39318.1 - 4.6e-05 23.4 0.0 9.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KPI39318.1 - 0.0014 17.6 0.0 0.024 13.6 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 KPI39318.1 - 0.0018 18.3 0.0 0.0036 17.2 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF938 PF06080.7 KPI39318.1 - 0.0046 16.5 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) CMAS PF02353.15 KPI39318.1 - 0.015 14.3 0.0 0.036 13.1 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 KPI39318.1 - 0.044 13.1 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 KPI39318.1 - 0.074 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.13 KPI39318.1 - 0.096 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase BTB PF00651.26 KPI39319.1 - 4.8e-08 32.9 0.0 8.7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF1761 PF08570.5 KPI39320.1 - 0.0032 17.4 1.7 0.0032 17.4 1.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1761) DUF4401 PF14351.1 KPI39320.1 - 0.035 13.1 6.3 0.014 14.4 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) DUF4405 PF14358.1 KPI39320.1 - 0.26 11.4 0.2 0.26 11.4 0.2 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4405) SUR7 PF06687.7 KPI39320.1 - 0.35 10.3 13.7 1.3 8.5 7.6 2.6 1 1 1 2 2 2 0 SUR7/PalI family Herpes_LMP1 PF05297.6 KPI39320.1 - 3.7 6.3 8.2 5.1 5.9 5.7 1.3 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Tetraspannin PF00335.15 KPI39320.1 - 5.4 6.2 16.6 0.65 9.2 6.1 2.2 1 1 2 3 3 3 0 Tetraspanin family DUF2569 PF10754.4 KPI39320.1 - 8.1 6.6 11.3 14 5.8 4.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) Oxidored_FMN PF00724.15 KPI39321.1 - 1.5e-63 214.8 0.0 1.9e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 KPI39321.1 - 0.046 12.5 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) WD40 PF00400.27 KPI39324.1 - 1.3e-48 161.2 18.0 1.4e-08 34.3 0.0 8.8 8 2 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 KPI39324.1 - 2.4e-05 22.7 0.0 0.047 11.8 0.0 3.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF3312 PF11768.3 KPI39324.1 - 0.34 9.1 0.0 0.54 8.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Isochorismatase PF00857.15 KPI39325.1 - 7.7e-22 78.0 0.0 6.3e-14 52.2 0.0 2.3 2 0 0 2 2 2 2 Isochorismatase family Fe_dep_repress PF01325.14 KPI39328.1 - 0.0056 16.6 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Acyltransferase PF01553.16 KPI39329.1 - 3.7e-31 107.3 0.0 5.3e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DEAD PF00270.24 KPI39330.1 - 3e-40 137.4 1.0 4.8e-40 136.8 0.7 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI39330.1 - 1.1e-22 79.6 0.1 4.6e-11 42.4 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KPI39330.1 - 8.7e-06 25.6 0.0 2.4e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TRAUB PF08164.7 KPI39331.1 - 8.4e-24 83.4 0.1 4e-23 81.3 0.0 2.3 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 KPI39331.1 - 4.4e-22 78.6 4.0 4.4e-22 78.6 2.8 2.2 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor PGC7_Stella PF15549.1 KPI39331.1 - 3.5 7.6 8.9 0.13 12.2 0.8 2.5 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain Glyco_hydro_61 PF03443.9 KPI39332.1 - 4.1e-72 242.5 0.0 5.4e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KPI39332.1 - 4.4e-13 48.6 8.5 1e-12 47.4 5.9 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain RED_N PF07808.8 KPI39333.1 - 9.8e-10 38.0 4.3 9.8e-10 38.0 3.0 2.4 2 1 0 2 2 2 1 RED-like protein N-terminal region Methyltransf_15 PF09445.5 KPI39334.1 - 3.5e-47 159.9 0.0 5.1e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 KPI39334.1 - 1.6e-10 40.8 0.0 2.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KPI39334.1 - 4.2e-10 39.6 0.0 6.5e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KPI39334.1 - 9.5e-08 31.8 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 KPI39334.1 - 2.6e-07 31.2 0.0 4e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI39334.1 - 1.1e-05 25.1 0.0 2.6e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KPI39334.1 - 0.00057 19.3 0.0 0.00076 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.10 KPI39334.1 - 0.0018 17.7 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.11 KPI39334.1 - 0.0025 16.9 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase PrmA PF06325.8 KPI39334.1 - 0.0029 16.7 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 KPI39334.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 KPI39334.1 - 0.047 13.1 0.0 0.087 12.2 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) p450 PF00067.17 KPI39335.1 - 2.6e-70 237.2 0.0 3.2e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 API5 PF05918.6 KPI39336.1 - 0.38 9.2 2.5 0.47 8.8 1.8 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) F-box-like PF12937.2 KPI39338.1 - 0.045 13.4 0.1 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 KPI39338.1 - 0.053 13.1 0.1 0.17 11.6 0.0 1.9 1 0 0 1 1 1 0 F-box domain zf-BED PF02892.10 KPI39339.1 - 0.0046 16.6 0.3 0.0066 16.1 0.2 1.3 1 0 0 1 1 1 1 BED zinc finger DUF581 PF04570.9 KPI39339.1 - 0.069 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF581) BIR PF00653.16 KPI39339.1 - 0.72 10.3 3.8 1.4 9.4 0.5 2.4 2 1 0 2 2 2 0 Inhibitor of Apoptosis domain CsbD PF05532.7 KPI39340.1 - 0.0091 15.6 7.0 0.02 14.5 4.8 1.7 1 0 0 1 1 1 1 CsbD-like DUF977 PF06163.6 KPI39340.1 - 0.067 12.9 0.2 0.097 12.4 0.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Dicty_REP PF05086.7 KPI39340.1 - 1.5 6.4 8.0 1.5 6.4 5.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AF-4 PF05110.8 KPI39340.1 - 1.9 6.2 14.6 2 6.1 10.1 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CKAP2_C PF15297.1 KPI39340.1 - 3.8 6.2 8.6 4.2 6.0 5.9 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Ribosomal_L18_c PF14204.1 KPI39340.1 - 8.9 6.9 8.8 4.4 7.9 0.4 2.1 1 1 1 2 2 2 0 Ribosomal L18 C-terminal region SnoaL_2 PF12680.2 KPI39341.1 - 0.00047 20.5 0.0 0.00068 19.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 KPI39341.1 - 0.0025 17.3 0.0 0.0059 16.1 0.0 1.7 1 1 1 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.1 KPI39341.1 - 0.039 14.0 0.0 0.062 13.3 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain DUF508 PF04370.7 KPI39341.1 - 0.05 13.2 0.5 0.16 11.6 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF508) TMEM171 PF15471.1 KPI39341.1 - 0.067 11.9 0.2 0.087 11.6 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 PMI_typeI PF01238.16 KPI39342.1 - 1.1e-72 245.1 0.2 1e-71 241.9 0.1 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I DNA_ligase_A_N PF04675.9 KPI39342.1 - 0.005 16.6 0.1 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus AraC_binding PF02311.14 KPI39342.1 - 0.01 15.5 0.0 0.068 12.8 0.0 2.1 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_2 PF07883.6 KPI39342.1 - 0.14 11.6 0.1 6.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Cupin domain Beta-lactamase PF00144.19 KPI39343.1 - 8.5e-24 84.1 0.6 1.3e-23 83.5 0.4 1.2 1 0 0 1 1 1 1 Beta-lactamase S6PP_C PF08472.5 KPI39343.1 - 0.3 10.7 1.4 0.44 10.1 0.1 1.9 2 0 0 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal F-actin_cap_A PF01267.12 KPI39344.1 - 1.4e-77 260.3 0.0 1.6e-77 260.2 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit TauD PF02668.11 KPI39346.1 - 1.4e-33 116.6 0.4 1.9e-33 116.2 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KPI39346.1 - 0.057 12.3 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 CsiD AAA PF00004.24 KPI39347.1 - 2.4e-17 63.3 0.0 4.9e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KPI39347.1 - 0.001 19.2 0.1 0.019 15.1 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KPI39347.1 - 0.0012 18.8 0.0 0.004 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Zot PF05707.7 KPI39347.1 - 0.0045 16.4 0.0 0.28 10.6 0.0 2.3 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) RuvB_N PF05496.7 KPI39347.1 - 0.0053 15.8 0.0 0.0091 15.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KPI39347.1 - 0.0076 17.0 0.0 0.022 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KPI39347.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KPI39347.1 - 0.049 13.5 0.0 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KPI39347.1 - 0.053 13.8 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KPI39347.1 - 0.061 13.0 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 KPI39347.1 - 0.066 12.3 0.0 0.17 10.9 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KPI39347.1 - 0.081 12.4 0.1 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KPI39347.1 - 0.15 11.1 0.3 0.44 9.6 0.0 1.8 2 0 0 2 2 2 0 KaiC ArgK PF03308.11 KPI39347.1 - 0.17 10.5 0.1 1.4 7.6 0.0 2.2 3 0 0 3 3 3 0 ArgK protein AOX PF01786.12 KPI39348.1 - 1e-75 253.7 1.2 1.3e-74 250.1 0.8 2.0 1 1 0 1 1 1 1 Alternative oxidase Glyoxalase_2 PF12681.2 KPI39349.1 - 1.6e-15 57.6 0.0 2e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KPI39349.1 - 1.6e-11 44.2 0.0 4e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KPI39349.1 - 4.4e-07 29.8 0.0 6.6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KPI39349.1 - 3.7e-05 23.7 0.0 0.0012 18.7 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Sugar_tr PF00083.19 KPI39350.1 - 7.5e-78 262.1 16.6 8.9e-78 261.8 11.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI39350.1 - 1.1e-11 44.0 26.9 1.1e-11 44.0 18.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cu-oxidase_3 PF07732.10 KPI39351.1 - 4.7e-40 135.9 4.9 1.4e-38 131.2 0.5 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KPI39351.1 - 1.8e-35 121.4 9.4 3.9e-33 113.8 0.2 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KPI39351.1 - 1.6e-17 63.8 0.2 4.7e-15 55.8 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase DUF4012 PF13196.1 KPI39351.1 - 0.066 13.3 0.1 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4012) Glyco_hydro_47 PF01532.15 KPI39352.1 - 1.8e-168 560.9 0.0 2.1e-168 560.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Gpi16 PF04113.9 KPI39353.1 - 9.6e-222 736.9 0.0 1.2e-221 736.6 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component BUD22 PF09073.5 KPI39354.1 - 6.7e-67 226.4 12.8 8.1e-67 226.1 8.9 1.0 1 0 0 1 1 1 1 BUD22 Arrestin_N PF00339.24 KPI39356.1 - 1.7e-06 27.9 0.0 4.2e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Glyco_hydro_3 PF00933.16 KPI39357.1 - 1.9e-74 250.3 0.0 3e-74 249.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KPI39357.1 - 3.1e-54 183.9 0.0 5.5e-53 179.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KPI39357.1 - 2.8e-18 65.6 0.0 5.9e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KPI39357.1 - 6.5e-07 29.1 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 PA14 domain DUF4414 PF14377.1 KPI39358.1 - 1.7e-17 63.2 1.9 1.8e-06 27.8 0.1 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF4414) DUF1019 PF06254.6 KPI39358.1 - 0.019 15.0 0.2 22 5.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1019) MgtE_N PF03448.12 KPI39358.1 - 0.094 13.0 1.5 16 5.8 0.0 3.1 3 0 0 3 3 3 0 MgtE intracellular N domain TauD PF02668.11 KPI39359.1 - 1.4e-46 159.3 0.1 1.6e-46 159.0 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DoxX_2 PF13564.1 KPI39360.1 - 0.12 12.3 4.9 0.95 9.4 0.4 2.6 2 0 0 2 2 2 0 DoxX-like family DUF4131 PF13567.1 KPI39360.1 - 0.34 10.2 3.7 1.7 8.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF159 PF02586.9 KPI39361.1 - 2.7e-57 193.6 0.0 3.9e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 DIOX_N PF14226.1 KPI39362.1 - 1.6e-18 67.3 0.0 4e-18 66.0 0.0 1.6 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI39362.1 - 2.4e-14 53.4 0.0 4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 KPI39363.1 - 4.9e-26 89.6 10.5 7.2e-07 28.8 0.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat PD40 PF07676.7 KPI39363.1 - 9.8e-05 21.9 0.1 0.35 10.6 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KPI39363.1 - 0.0013 18.5 0.1 0.0039 16.9 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KPI39363.1 - 0.0023 16.3 0.0 0.0088 14.3 0.0 1.8 1 1 1 2 2 2 2 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 KPI39363.1 - 0.043 13.1 0.4 3.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature RuvA_C PF07499.8 KPI39364.1 - 0.021 14.9 0.2 25 5.1 0.0 4.0 4 0 0 4 4 4 0 RuvA, C-terminal domain GRASP55_65 PF04495.9 KPI39365.1 - 9.9e-40 135.7 0.0 1.8e-38 131.6 0.0 2.1 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain RCC1 PF00415.13 KPI39366.1 - 3.5e-22 78.3 0.1 4.6e-07 29.9 0.0 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KPI39366.1 - 2e-17 63.1 0.1 5e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 KPI39366.1 - 2.2e-09 37.5 0.6 9.6e-05 22.7 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) RCC1_2 PF13540.1 KPI39366.1 - 7.3e-08 31.8 2.3 4.2e-07 29.4 0.2 3.2 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 KPI39366.1 - 5.4e-05 23.0 0.5 0.88 9.9 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 KPI39366.1 - 0.00019 21.7 0.0 0.0028 17.9 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KPI39366.1 - 0.0017 18.0 0.1 0.34 10.8 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KPI39366.1 - 0.016 15.4 3.1 3.1 8.1 0.0 3.6 4 1 0 4 4 4 0 Ankyrin repeats (many copies) FHIPEP PF00771.15 KPI39366.1 - 0.022 13.1 0.1 0.022 13.1 0.0 1.4 2 0 0 2 2 2 0 FHIPEP family RrnaAD PF00398.15 KPI39367.1 - 9.6e-55 185.4 0.0 1.3e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KPI39367.1 - 4.4e-10 39.5 0.0 8.2e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KPI39367.1 - 0.00048 19.7 0.0 0.00078 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KPI39367.1 - 0.00054 20.5 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KPI39367.1 - 0.00064 19.1 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KPI39367.1 - 0.0012 18.5 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KPI39367.1 - 0.0033 16.6 0.1 0.0068 15.6 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase UPF0020 PF01170.13 KPI39367.1 - 0.0064 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.15 KPI39367.1 - 0.013 14.6 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 KPI39367.1 - 0.013 14.5 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 KPI39367.1 - 0.02 15.2 0.0 0.056 13.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 KPI39367.1 - 0.022 14.3 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_12 PF08242.7 KPI39367.1 - 0.028 14.8 0.0 0.077 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KPI39367.1 - 0.03 13.9 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KPI39367.1 - 0.069 12.2 0.1 0.18 10.9 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) WSC PF01822.14 KPI39368.1 - 5.5e-20 71.0 9.3 5.5e-20 71.0 6.4 3.5 2 1 0 2 2 2 1 WSC domain NAD_binding_2 PF03446.10 KPI39369.1 - 6.1e-42 143.2 0.8 8.2e-42 142.8 0.6 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KPI39369.1 - 3.2e-30 104.6 0.0 6e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 KPI39369.1 - 8.7e-05 21.4 0.0 0.00015 20.6 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Indigoidine_A PF04227.7 KPI39370.1 - 6.3e-113 376.8 0.9 1.1e-112 376.0 0.6 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 KPI39370.1 - 3.7e-20 72.2 0.8 3.7e-11 42.7 0.0 3.1 3 1 0 3 3 3 2 pfkB family carbohydrate kinase L31 PF09784.4 KPI39371.1 - 2.8e-45 152.6 2.1 3.1e-45 152.4 1.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 DUF2161 PF09929.4 KPI39371.1 - 0.038 13.9 0.3 0.071 13.0 0.0 1.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2161) UCH PF00443.24 KPI39372.1 - 1.1e-46 159.1 0.0 1.8e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KPI39372.1 - 2.4e-18 66.6 0.0 1.1e-17 64.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 KPI39372.1 - 8.1e-16 57.3 0.3 7.1e-07 28.8 0.0 2.9 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.14 KPI39372.1 - 2e-07 31.0 0.7 6.4e-07 29.3 0.5 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UBA_4 PF14555.1 KPI39372.1 - 0.00049 19.5 0.0 0.0019 17.6 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain CUE PF02845.11 KPI39372.1 - 0.05 13.1 0.1 13 5.4 0.0 2.6 2 0 0 2 2 2 0 CUE domain PAP1 PF08601.5 KPI39373.1 - 1.2e-52 179.7 46.4 3.5e-52 178.2 30.0 3.1 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 KPI39373.1 - 1.3e-10 41.0 7.4 3.2e-10 39.8 5.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KPI39373.1 - 0.0065 16.2 12.2 0.015 15.0 7.3 2.2 1 1 1 2 2 2 1 Basic region leucine zipper DUF16 PF01519.11 KPI39373.1 - 0.019 15.1 0.7 0.068 13.3 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function DUF16 XhlA PF10779.4 KPI39373.1 - 0.13 12.2 2.8 0.4 10.6 2.0 1.8 1 0 0 1 1 1 0 Haemolysin XhlA Adeno_PIX PF03955.9 KPI39373.1 - 1.9 9.0 7.2 0.22 12.0 0.2 2.5 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) IncA PF04156.9 KPI39373.1 - 2.8 7.4 11.7 0.22 11.1 2.3 2.2 2 0 0 2 2 2 0 IncA protein GAS PF13851.1 KPI39373.1 - 8.6 5.4 10.9 0.73 8.9 3.7 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding PRP1_N PF06424.7 KPI39374.1 - 3.2e-50 169.9 7.9 3.2e-50 169.9 5.5 2.7 3 0 0 3 3 3 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KPI39374.1 - 1.6e-28 96.5 25.2 0.0059 17.1 1.6 13.9 5 4 9 14 14 14 11 Tetratricopeptide repeat TPR_19 PF14559.1 KPI39374.1 - 3.8e-22 78.3 4.7 3e-06 27.4 0.1 9.4 7 2 3 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 KPI39374.1 - 1.3e-18 67.1 9.4 6e-06 26.7 0.5 8.5 6 2 2 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 KPI39374.1 - 1.4e-14 52.7 1.8 0.072 13.0 0.0 8.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_11 PF13414.1 KPI39374.1 - 4.4e-12 45.4 6.7 0.082 12.5 0.0 8.3 5 2 4 10 10 10 3 TPR repeat TPR_17 PF13431.1 KPI39374.1 - 1.6e-09 37.2 0.1 10 6.6 0.0 8.9 9 1 0 9 9 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 KPI39374.1 - 6.3e-08 31.8 0.2 0.044 13.5 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KPI39374.1 - 6.1e-07 28.7 0.1 0.06 12.9 0.0 4.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KPI39374.1 - 5.8e-05 22.9 3.4 0.56 10.1 0.0 5.8 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 KPI39374.1 - 0.0007 19.8 5.3 20 5.9 0.0 8.6 11 0 0 11 11 11 0 Tetratricopeptide repeat DUF3808 PF10300.4 KPI39374.1 - 0.0026 16.3 0.1 3.4 6.1 0.0 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF3808) TPR_7 PF13176.1 KPI39374.1 - 0.012 15.2 0.2 4.7 7.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 KPI39374.1 - 1.7 8.5 18.9 0.089 12.7 1.3 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat AD PF09793.4 KPI39375.1 - 4.2e-11 42.5 0.0 6.9e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain LSM14 PF12701.2 KPI39375.1 - 0.026 14.3 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Scd6-like Sm domain ADSL_C PF10397.4 KPI39376.1 - 1.3e-14 53.9 0.0 1.6e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus COX15-CtaA PF02628.10 KPI39377.1 - 5.4e-97 324.2 13.8 6.4e-97 324.0 9.6 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Corona_S2 PF01601.11 KPI39378.1 - 0.062 11.3 8.6 0.084 10.9 5.9 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein LSR PF05624.9 KPI39378.1 - 0.18 11.5 22.9 0.27 11.0 15.9 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Piwi PF02171.12 KPI39379.1 - 0.049 12.5 0.1 0.071 12.0 0.1 1.2 1 0 0 1 1 1 0 Piwi domain Sugar_tr PF00083.19 KPI39381.1 - 5.5e-59 199.9 30.6 6.3e-59 199.7 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI39381.1 - 1.4e-16 60.1 75.3 7.2e-16 57.8 28.7 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI39381.1 - 0.00081 17.8 36.4 0.0032 15.9 8.2 3.7 2 2 1 3 3 3 3 MFS/sugar transport protein SopD PF11047.3 KPI39382.1 - 0.14 11.0 0.6 0.34 9.8 0.1 1.7 2 0 0 2 2 2 0 Salmonella outer protein D DUF148 PF02520.12 KPI39382.1 - 0.97 9.2 3.7 1.6 8.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF148 RNase_P_pop3 PF08228.6 KPI39383.1 - 3.4e-06 26.9 0.0 8.2e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 RNase P subunit Pop3 Beta-lactamase PF00144.19 KPI39384.1 - 4.7e-43 147.4 0.3 1.3e-42 146.0 0.1 1.7 2 0 0 2 2 2 1 Beta-lactamase Velvet PF11754.3 KPI39385.1 - 5.1e-26 91.5 0.0 6.5e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Velvet factor SH3_9 PF14604.1 KPI39386.1 - 0.0002 20.8 0.1 0.0002 20.8 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KPI39386.1 - 0.0011 18.2 0.1 0.002 17.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KPI39386.1 - 0.059 12.8 0.4 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 Variant SH3 domain DUF2321 PF10083.4 KPI39386.1 - 0.48 9.8 4.3 1.3 8.4 3.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) SNARE PF05739.14 KPI39387.1 - 1.2e-18 66.5 2.8 1.2e-18 66.5 1.9 3.6 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 KPI39387.1 - 1e-11 44.9 2.6 2.1e-11 43.8 0.2 2.3 2 0 0 2 2 2 1 Syntaxin DNA_repr_REX1B PF14966.1 KPI39387.1 - 0.011 16.1 0.2 0.072 13.4 0.0 2.4 2 0 0 2 2 2 0 DNA repair REX1-B MCPsignal PF00015.16 KPI39387.1 - 0.037 13.5 9.1 0.076 12.5 1.1 2.5 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SlyX PF04102.7 KPI39387.1 - 0.052 13.9 2.6 13 6.2 0.1 3.3 2 1 0 2 2 2 0 SlyX Syntaxin_2 PF14523.1 KPI39387.1 - 5.7 7.0 7.0 1.1 9.3 1.6 2.1 2 1 0 2 2 2 0 Syntaxin-like protein His_biosynth PF00977.16 KPI39388.1 - 2.8e-48 164.1 2.3 6.5e-47 159.7 1.6 3.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 KPI39388.1 - 8.8e-28 97.0 0.0 1.6e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 KPI39388.1 - 7.8e-09 35.4 0.0 7e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KPI39388.1 - 1.5e-08 34.4 0.0 4e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 KPI39388.1 - 0.00073 19.0 0.0 0.0035 16.8 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 Dus PF01207.12 KPI39388.1 - 0.039 12.7 0.0 0.077 11.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Peptidase_S51 PF03575.12 KPI39388.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S51 Pkinase PF00069.20 KPI39389.1 - 2.1e-69 233.5 0.0 3.7e-69 232.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI39389.1 - 5.3e-46 156.7 0.0 8.9e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KPI39389.1 - 5.1e-16 58.8 0.0 2.6e-15 56.5 0.0 2.4 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 KPI39389.1 - 2.6e-06 26.6 0.0 4.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.7 KPI39389.1 - 0.016 14.4 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.18 KPI39389.1 - 0.055 13.1 0.1 0.31 10.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KPI39389.1 - 0.19 10.7 0.4 0.57 9.2 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pinin_SDK_memA PF04696.8 KPI39390.1 - 4.3e-14 52.2 14.7 6.5e-14 51.6 10.2 1.2 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region PAT1 PF09770.4 KPI39390.1 - 6.6 4.8 11.1 0.52 8.4 4.6 1.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 OST3_OST6 PF04756.8 KPI39391.1 - 5e-15 55.4 1.5 7.7e-15 54.8 1.1 1.3 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 KPI39391.1 - 0.0046 16.6 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Endonuclease_NS PF01223.18 KPI39393.1 - 2.9e-58 196.9 0.0 3.8e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease adh_short PF00106.20 KPI39394.1 - 1.6e-17 63.9 0.0 2.3e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI39394.1 - 2e-05 24.3 0.0 3.7e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI39394.1 - 0.0075 16.0 0.0 0.013 15.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KPI39394.1 - 0.73 9.8 3.8 11 6.0 0.1 2.5 2 1 0 2 2 2 0 NADH(P)-binding TPR_12 PF13424.1 KPI39395.1 - 5e-06 26.3 4.5 0.0026 17.6 0.8 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat MAS20 PF02064.10 KPI39395.1 - 1.9e-05 24.5 0.1 0.0002 21.2 0.0 2.5 2 0 0 2 2 2 1 MAS20 protein import receptor TPR_8 PF13181.1 KPI39395.1 - 4.8e-05 22.8 0.1 3.8 7.4 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KPI39395.1 - 0.00043 19.9 1.2 1.6 8.8 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KPI39395.1 - 0.0032 17.8 4.6 1.8 9.2 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KPI39395.1 - 0.006 17.1 0.1 1.2 9.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KPI39395.1 - 0.2 11.6 2.5 2 8.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat NUDE_C PF04880.8 KPI39397.1 - 9.3e-17 61.8 16.4 9.3e-17 61.8 11.4 5.5 3 1 0 4 4 4 1 NUDE protein, C-terminal conserved region WEMBL PF05701.6 KPI39397.1 - 0.044 12.2 32.9 0.072 11.5 22.8 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Peptidase_S64 PF08192.6 KPI39397.1 - 0.099 10.9 12.3 0.18 10.1 8.6 1.3 1 0 0 1 1 1 0 Peptidase family S64 Tropomyosin_1 PF12718.2 KPI39397.1 - 0.66 9.8 40.9 2.8 7.7 20.3 4.3 2 1 1 3 3 3 0 Tropomyosin like ALMT PF11744.3 KPI39397.1 - 1.5 7.3 4.8 2.3 6.7 3.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter ATG16 PF08614.6 KPI39397.1 - 1.7 8.4 37.1 0.44 10.3 22.1 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.3 KPI39397.1 - 3.4 4.8 27.9 5.7 4.1 19.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Peptidase_S46 PF10459.4 KPI39397.1 - 3.9 5.7 14.3 5.9 5.1 9.9 1.2 1 0 0 1 1 1 0 Peptidase S46 IncA PF04156.9 KPI39397.1 - 4.6 6.7 38.4 0.73 9.3 14.0 2.9 2 1 1 3 3 3 0 IncA protein ADIP PF11559.3 KPI39397.1 - 9.9 6.0 39.0 0.17 11.7 9.6 3.9 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding FAA_hydrolase PF01557.13 KPI39398.1 - 1.4e-47 161.9 0.0 1.8e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family IMS PF00817.15 KPI39399.1 - 1.6e-41 141.5 0.0 2.7e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KPI39399.1 - 3.8e-15 55.9 0.0 7.4e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 KPI39399.1 - 1.1e-07 31.9 0.0 8.1e-07 29.0 0.0 2.5 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 KPI39399.1 - 2.2e-06 27.3 2.1 4.4e-06 26.4 0.1 2.7 3 0 0 3 3 3 1 IMS family HHH motif PTCB-BRCT PF12738.2 KPI39399.1 - 1.9e-05 24.4 0.1 6.1e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain HHH_5 PF14520.1 KPI39399.1 - 0.014 15.5 0.3 0.17 12.0 0.0 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix domain DUF1805 PF08827.6 KPI39399.1 - 0.068 12.9 0.0 0.2 11.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Cdd1 PF11731.3 KPI39399.1 - 0.11 12.4 0.0 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 Pathogenicity locus Aldo_ket_red PF00248.16 KPI39401.1 - 5.8e-35 120.4 0.0 6.8e-34 116.9 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family GPAT_N PF14829.1 KPI39401.1 - 0.006 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase N-terminal SelR PF01641.13 KPI39402.1 - 7.3e-51 171.0 0.3 9.5e-51 170.6 0.2 1.1 1 0 0 1 1 1 1 SelR domain GFA PF04828.9 KPI39402.1 - 0.0051 16.7 1.0 0.29 11.1 0.0 2.3 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF2296 PF10058.4 KPI39402.1 - 0.006 16.3 0.3 0.94 9.2 0.0 2.3 2 0 0 2 2 2 2 Predicted integral membrane metal-binding protein (DUF2296) DZR PF12773.2 KPI39402.1 - 0.015 15.1 1.1 3 7.7 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 KPI39402.1 - 0.016 14.5 1.5 0.36 10.1 0.2 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zf-Mss51 PF13824.1 KPI39402.1 - 0.97 9.3 4.4 6 6.8 0.6 3.0 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Minor_capsid_3 PF12691.2 KPI39403.1 - 0.065 12.9 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage Glyco_hydro_cc PF11790.3 KPI39404.1 - 6.9e-47 159.8 0.0 8.6e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core HET PF06985.6 KPI39406.1 - 5.4e-29 101.1 0.0 8.5e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1281 PF06924.6 KPI39406.1 - 0.087 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF3433 PF11915.3 KPI39407.1 - 4.9e-27 93.9 15.1 3e-19 68.9 3.2 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) ECH PF00378.15 KPI39408.1 - 3.1e-31 108.3 0.1 4e-31 108.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Ribophorin_I PF04597.9 KPI39409.1 - 6.5e-134 446.6 0.0 7.5e-134 446.4 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I CBP4 PF07960.6 KPI39410.1 - 0.05 13.2 0.1 0.074 12.6 0.1 1.2 1 0 0 1 1 1 0 CBP4 DUF1183 PF06682.7 KPI39410.1 - 0.062 12.8 1.5 0.075 12.6 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) LSR PF05624.9 KPI39410.1 - 0.095 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) RCR PF12273.3 KPI39410.1 - 0.34 11.4 14.9 1.6 9.3 10.3 2.1 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red ADH_zinc_N PF00107.21 KPI39411.1 - 1.5e-22 79.4 0.6 2.3e-22 78.9 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI39411.1 - 3.1e-22 78.3 1.4 6e-22 77.4 1.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KPI39411.1 - 2.2e-07 31.7 0.0 3.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_6 PF12697.2 KPI39413.1 - 5.6e-21 75.4 0.2 7.1e-21 75.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI39413.1 - 1.4e-13 50.9 0.0 1.3e-11 44.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI39413.1 - 3.3e-13 49.6 0.0 1.2e-12 47.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KPI39413.1 - 4.2e-05 23.2 0.0 6.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI39413.1 - 0.00021 20.6 0.0 0.091 11.9 0.0 2.9 2 1 1 3 3 3 1 Prolyl oligopeptidase family UPF0227 PF05728.7 KPI39413.1 - 0.0008 19.1 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0227) FSH1 PF03959.8 KPI39413.1 - 0.057 12.8 0.0 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DUF2235 PF09994.4 KPI39413.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Ndr PF03096.9 KPI39413.1 - 0.12 10.8 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family UPF0075 PF03702.9 KPI39414.1 - 2.2e-73 247.2 0.0 2.6e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) Histone PF00125.19 KPI39415.1 - 7e-15 54.9 0.2 1e-14 54.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KPI39415.1 - 0.00012 21.9 0.2 0.00018 21.3 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KPI39415.1 - 0.0002 21.3 0.1 0.00034 20.6 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 KPI39415.1 - 0.00022 21.3 0.1 0.00043 20.4 0.0 1.6 1 1 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 KPI39415.1 - 0.0083 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 KPI39415.1 - 0.018 14.3 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Abhydrolase_6 PF12697.2 KPI39416.1 - 3e-18 66.5 0.4 1.5e-17 64.2 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI39416.1 - 1.7e-08 34.2 0.0 2.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI39416.1 - 4e-07 29.8 0.0 3.4e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KPI39416.1 - 0.011 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase UCH PF00443.24 KPI39417.1 - 2.2e-43 148.2 0.1 3.9e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KPI39417.1 - 2.5e-22 79.6 0.0 5e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 KPI39417.1 - 8.9e-19 67.2 1.4 1.6e-18 66.3 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) Citrus_P18 PF05520.6 KPI39418.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Citrus tristeza virus P18 protein Mito_carr PF00153.22 KPI39421.1 - 4.1e-46 154.6 5.0 1.1e-16 60.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2048 PF09752.4 KPI39421.1 - 0.072 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) SseC PF04888.7 KPI39422.1 - 0.089 12.1 3.1 0.16 11.2 2.2 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Nucleo_P87 PF07267.6 KPI39422.1 - 4.8 5.7 7.7 6.9 5.2 5.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 LRR19-TM PF15176.1 KPI39422.1 - 6.5 6.5 8.6 0.82 9.3 0.1 3.1 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain P5CR_dimer PF14748.1 KPI39423.1 - 7.5e-33 112.7 1.3 1.4e-32 111.8 0.9 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KPI39423.1 - 9.7e-12 45.1 1.1 7.6e-10 39.0 0.0 3.3 4 0 0 4 4 4 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KPI39423.1 - 0.044 13.2 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PDH PF02153.12 KPI39423.1 - 0.067 12.0 0.0 0.36 9.6 0.0 1.9 1 1 0 1 1 1 0 Prephenate dehydrogenase FAD_binding_4 PF01565.18 KPI39424.1 - 2.4e-29 101.5 2.3 3.9e-29 100.9 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KPI39424.1 - 1.3e-12 47.4 0.2 3e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_11 PF08241.7 KPI39425.1 - 1.3e-12 48.0 0.0 3.9e-12 46.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI39425.1 - 1.3e-09 38.3 0.0 6e-09 36.2 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI39425.1 - 7.2e-09 36.2 0.0 1.3e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI39425.1 - 1e-08 35.4 0.0 1.8e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI39425.1 - 7.1e-08 32.3 0.0 1.2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI39425.1 - 7.8e-08 32.0 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI39425.1 - 0.00032 20.7 0.0 0.0022 18.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 KPI39425.1 - 0.0092 14.8 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_9 PF08003.6 KPI39425.1 - 0.16 10.6 0.0 0.27 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) VHS PF00790.14 KPI39426.1 - 2e-33 115.0 1.0 3.9e-33 114.0 0.7 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 KPI39426.1 - 3.4e-16 58.3 0.0 8.6e-16 57.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KPI39426.1 - 1.7e-15 56.2 0.1 3.6e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KPI39426.1 - 1.6e-14 53.0 0.0 2.9e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 KPI39426.1 - 0.039 13.9 4.1 0.034 14.1 1.4 2.0 2 0 0 2 2 2 0 GAT domain UIM PF02809.15 KPI39426.1 - 0.15 11.7 2.3 0.44 10.2 1.6 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif dCMP_cyt_deam_1 PF00383.17 KPI39427.1 - 4.7e-25 87.1 1.5 6.7e-25 86.6 1.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 KPI39427.1 - 0.0035 18.1 0.0 0.007 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KPI39427.1 - 0.0098 16.1 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Pkr1 PF08636.5 KPI39428.1 - 1.3e-32 111.6 5.6 1.7e-32 111.2 3.9 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Kei1 PF08552.6 KPI39428.1 - 0.039 13.6 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 OAD_gamma PF04277.8 KPI39428.1 - 0.12 12.7 0.2 0.87 10.0 0.0 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Cofilin_ADF PF00241.15 KPI39429.1 - 2e-15 56.7 0.0 3.3e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF3538 PF12057.3 KPI39430.1 - 0.0026 17.3 1.8 0.0059 16.1 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3538) TPR_MLP1_2 PF07926.7 KPI39430.1 - 0.0037 17.0 17.3 0.0037 17.0 12.0 5.0 2 2 2 4 4 4 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KPI39430.1 - 1.3 8.1 16.9 0.72 8.9 4.4 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 KPI39430.1 - 7.4 6.1 61.3 0.75 9.3 7.6 4.1 2 1 2 4 4 4 0 IncA protein RabGAP-TBC PF00566.13 KPI39431.1 - 1.1e-48 165.4 0.0 1.4e-46 158.6 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain An_peroxidase PF03098.10 KPI39432.1 - 1.3e-72 244.8 0.0 3.5e-70 236.8 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KPI39432.1 - 3.9e-08 32.2 0.0 9.8e-08 30.9 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 Zip PF02535.17 KPI39433.1 - 3.5e-30 105.1 2.8 5.4e-30 104.4 1.9 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter SepZ PF06066.6 KPI39433.1 - 0.052 13.5 0.5 0.15 12.0 0.4 1.8 1 0 0 1 1 1 0 SepZ Yippee-Mis18 PF03226.9 KPI39434.1 - 2.1e-21 75.7 0.7 3.7e-21 74.9 0.5 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Transp_Tc5_C PF04236.10 KPI39434.1 - 0.31 11.2 2.3 0.59 10.4 0.3 2.1 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Pkinase PF00069.20 KPI39435.1 - 1.2e-29 103.2 0.0 1e-23 83.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KPI39435.1 - 7.6e-14 51.4 0.0 4.8e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KPI39435.1 - 0.0038 16.9 0.9 0.0068 16.1 0.5 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KPI39435.1 - 0.056 12.2 0.0 0.077 11.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Homeobox_KN PF05920.6 KPI39436.1 - 2.8e-20 71.7 0.8 4.6e-20 71.0 0.6 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KPI39436.1 - 3.1e-06 26.7 0.3 5.6e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 Homeobox domain Ank_4 PF13637.1 KPI39438.1 - 0.011 16.2 0.1 0.036 14.5 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.25 KPI39438.1 - 0.03 14.1 0.1 0.13 12.0 0.0 2.1 3 0 0 3 3 3 0 Ankyrin repeat Rad21_Rec8_N PF04825.8 KPI39439.1 - 1.2e-36 125.0 0.0 2e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KPI39439.1 - 4.6e-08 32.1 0.0 1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein EF-hand_1 PF00036.27 KPI39440.1 - 3.4e-41 135.3 12.3 1.2e-09 36.7 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KPI39440.1 - 2.4e-36 123.6 6.2 7.2e-20 70.8 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KPI39440.1 - 2.2e-35 120.0 11.9 7.6e-16 57.4 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KPI39440.1 - 6.6e-31 103.3 7.8 6e-10 38.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KPI39440.1 - 7e-26 88.3 9.4 1.8e-06 27.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KPI39440.1 - 1.8e-15 56.5 0.3 3e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KPI39440.1 - 3.8e-09 36.2 1.9 0.00069 19.3 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KPI39440.1 - 1.1e-08 35.0 0.1 0.0043 17.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 KPI39440.1 - 4.1e-08 32.7 0.1 0.024 14.2 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KPI39440.1 - 3.8e-07 29.9 1.8 5.1e-06 26.3 0.2 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 KPI39440.1 - 0.00016 21.4 1.3 0.34 10.6 0.0 2.7 1 1 2 3 3 3 2 Tellurite resistance protein TerB Caleosin PF05042.8 KPI39440.1 - 0.00034 20.2 0.2 0.11 12.1 0.0 2.8 1 1 1 3 3 3 1 Caleosin related protein RNA_pol_Rpb4 PF03874.11 KPI39440.1 - 0.0028 17.6 0.7 1.4 8.9 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb4 Tenui_NCP PF04876.7 KPI39440.1 - 0.003 17.1 0.1 0.13 11.7 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 KPI39440.1 - 0.0078 16.5 1.5 1.9 8.8 0.0 2.5 1 1 1 2 2 2 1 Toprim-like DUF1104 PF06518.6 KPI39440.1 - 0.036 14.2 4.0 0.88 9.7 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DUF3349 PF11829.3 KPI39440.1 - 0.043 14.2 0.5 9.2 6.7 0.1 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 KPI39440.1 - 0.2 11.3 2.9 0.92 9.2 0.1 3.2 1 1 3 4 4 4 0 EF hand RloB PF13707.1 KPI39440.1 - 0.25 11.0 3.5 1.1 8.9 1.3 2.2 1 1 0 1 1 1 0 RloB-like protein PB1 PF00564.19 KPI39440.1 - 0.48 10.1 2.5 36 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain DUF3500 PF12006.3 KPI39441.1 - 6.4e-99 330.8 0.0 7.8e-99 330.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) p450 PF00067.17 KPI39442.1 - 2.9e-57 194.2 0.0 3.3e-57 194.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF747 PF05346.6 KPI39443.1 - 2.3e-123 411.4 4.9 3.4e-123 410.9 3.4 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family CD34_antigen PF06365.7 KPI39443.1 - 0.026 14.1 0.1 4.2 6.9 0.0 2.3 2 0 0 2 2 2 0 CD34/Podocalyxin family Methyltransf_23 PF13489.1 KPI39444.1 - 1.3e-08 34.7 0.0 1.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI39444.1 - 2.1e-06 27.4 0.0 8.4e-06 25.4 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI39444.1 - 9.4e-05 22.9 0.0 0.00027 21.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KPI39444.1 - 0.00084 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 KPI39444.1 - 0.0012 19.3 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI39444.1 - 0.0013 19.0 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI39444.1 - 0.0035 17.8 0.0 0.013 15.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KPI39444.1 - 0.0051 16.8 0.0 0.0063 16.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KPI39444.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KPI39444.1 - 0.014 14.5 0.0 0.027 13.6 0.0 1.3 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KPI39444.1 - 0.048 12.6 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 KPI39444.1 - 0.12 11.7 0.0 0.44 9.9 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase small domain DUF486 PF04342.7 KPI39444.1 - 0.18 11.8 0.0 0.31 11.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF486 GMC_oxred_N PF00732.14 KPI39445.1 - 4.3e-48 163.9 0.0 5.9e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI39445.1 - 5.2e-35 120.8 0.0 8.6e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KPI39445.1 - 2e-05 23.6 0.0 0.058 12.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI39445.1 - 0.00019 21.4 0.1 0.00052 19.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KPI39445.1 - 0.0022 16.9 0.1 0.0045 15.9 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 KPI39445.1 - 0.0078 15.1 0.0 1.6 7.5 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KPI39445.1 - 0.013 15.6 0.0 0.71 9.8 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI39445.1 - 0.014 14.4 0.2 0.033 13.2 0.0 1.6 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 KPI39445.1 - 0.07 11.5 0.1 0.14 10.5 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 KPI39445.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 KPI39445.1 - 0.16 11.7 2.3 0.35 10.6 0.0 2.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KPI39445.1 - 0.16 10.7 0.5 0.74 8.5 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain SIN1 PF05422.7 KPI39447.1 - 2.4e-32 112.1 0.1 2.8e-20 72.3 0.0 2.7 3 0 0 3 3 3 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 KPI39447.1 - 0.00084 19.2 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 GLUT4 regulating protein TUG DUF3456 PF11938.3 KPI39447.1 - 0.14 12.1 0.0 0.37 10.7 0.0 1.6 2 0 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP TFIIF_alpha PF05793.7 KPI39447.1 - 2.1 6.6 6.1 3.3 5.9 4.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) KfrA_N PF11740.3 KPI39449.1 - 0.0036 17.7 0.0 0.0055 17.1 0.0 1.3 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term PSI_PsaF PF02507.10 KPI39449.1 - 0.015 14.8 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III GerE PF00196.14 KPI39449.1 - 0.029 13.6 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_29 PF13551.1 KPI39449.1 - 0.14 12.3 0.1 0.85 9.7 0.0 2.2 1 1 1 2 2 2 0 Winged helix-turn helix DUF3328 PF11807.3 KPI39450.1 - 3.5e-28 98.7 2.4 2.9e-27 95.7 1.7 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Metal_resist PF13801.1 KPI39450.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Heavy-metal resistance DUF1469 PF07332.6 KPI39450.1 - 0.088 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Rad17 PF03215.10 KPI39451.1 - 4.7e-47 160.8 0.0 1.2e-46 159.4 0.0 1.6 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KPI39451.1 - 0.00014 21.5 0.5 0.00058 19.5 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 KPI39451.1 - 0.0065 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KPI39451.1 - 0.0073 15.2 0.1 0.017 14.0 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 KPI39451.1 - 0.029 13.9 0.0 0.029 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Peptidase_M16 PF00675.15 KPI39451.1 - 0.061 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) AAA_16 PF13191.1 KPI39451.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KPI39451.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 KPI39452.1 - 1.3e-68 230.9 0.0 1.7e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI39452.1 - 1.3e-38 132.5 0.0 1.8e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI39452.1 - 7.3e-06 25.1 0.0 1.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KPI39452.1 - 0.045 13.4 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ammonium_transp PF00909.16 KPI39453.1 - 1.8e-93 313.1 33.2 2e-93 313.0 21.2 1.8 1 1 1 2 2 2 2 Ammonium Transporter Family Bac_rhamnosid PF05592.6 KPI39454.1 - 7.4e-28 97.0 0.1 1e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KPI39454.1 - 1.3e-09 37.8 0.0 2.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain DUF608 PF04685.8 KPI39454.1 - 0.04 12.6 0.5 0.061 12.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF608 ATP_transf PF09830.4 KPI39455.1 - 8.3e-12 44.7 0.0 9.7e-12 44.5 0.0 1.2 1 0 0 1 1 1 1 ATP adenylyltransferase DUF1554 PF07588.6 KPI39455.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1554) Exo_endo_phos PF03372.18 KPI39456.1 - 5.1e-21 75.7 0.2 7e-21 75.2 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WW PF00397.21 KPI39458.1 - 0.16 11.8 5.3 0.18 11.7 0.8 2.5 2 0 0 2 2 2 0 WW domain DUF1932 PF09130.6 KPI39459.1 - 3.8e-15 55.3 0.0 7.5e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.10 KPI39459.1 - 3.3e-08 33.5 0.0 1.4e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KPI39459.1 - 4.6e-06 26.9 0.0 1.6e-05 25.2 0.0 1.9 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KPI39459.1 - 0.0017 17.5 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KPI39459.1 - 0.1 12.2 0.1 0.26 10.9 0.1 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF605 PF04652.11 KPI39459.1 - 1.1 8.5 7.3 1.5 8.1 5.1 1.1 1 0 0 1 1 1 0 Vta1 like PH PF00169.24 KPI39460.1 - 0.00028 21.0 0.0 0.00064 19.8 0.0 1.6 2 0 0 2 2 2 1 PH domain SOBP PF15279.1 KPI39460.1 - 6.2 7.1 8.4 12 6.1 1.3 2.5 2 1 0 2 2 2 0 Sine oculis-binding protein Mito_carr PF00153.22 KPI39461.1 - 4.1e-69 228.3 3.9 1.7e-24 85.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Clathrin_lg_ch PF01086.12 KPI39462.1 - 1.6e-57 195.0 9.0 7.6e-57 192.8 6.3 1.8 1 1 0 1 1 1 1 Clathrin light chain Complex1_LYR PF05347.10 KPI39463.1 - 8.5e-09 35.0 0.1 1.4e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KPI39463.1 - 4.4e-06 26.7 0.7 6.5e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KPI39463.1 - 2.3e-05 24.8 0.5 3.8e-05 24.1 0.3 1.5 1 1 0 1 1 1 1 Complex1_LYR-like PTPA PF03095.10 KPI39464.1 - 1.7e-108 362.3 0.0 2e-108 362.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Carboxyl_trans PF01039.17 KPI39465.1 - 9.8e-76 255.0 0.0 2e-75 254.0 0.0 1.4 1 1 0 1 1 1 1 Carboxyl transferase domain DUF1900 PF08954.6 KPI39467.1 - 7.9e-50 167.9 0.0 2.1e-49 166.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KPI39467.1 - 1.4e-32 111.1 0.0 2.4e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KPI39467.1 - 2.5e-20 71.5 0.6 1.2e-06 28.0 0.1 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat CENP-Q PF13094.1 KPI39467.1 - 0.0047 16.9 0.5 0.011 15.8 0.4 1.6 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DivIC PF04977.10 KPI39467.1 - 0.053 13.0 1.5 0.095 12.1 1.0 1.4 1 0 0 1 1 1 0 Septum formation initiator Lge1 PF11488.3 KPI39467.1 - 0.12 12.5 0.7 0.25 11.5 0.5 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 ADIP PF11559.3 KPI39467.1 - 0.18 11.7 3.2 0.26 11.1 2.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1843 PF08898.5 KPI39467.1 - 0.35 10.9 1.9 0.66 10.0 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) DUF3818 PF12825.2 KPI39468.1 - 8e-38 129.9 0.5 2.8e-22 78.8 0.6 2.3 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KPI39468.1 - 3.6e-22 78.4 0.0 6.8e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 PX-associated Metal_resist PF13801.1 KPI39468.1 - 0.041 13.8 0.3 0.041 13.8 0.2 1.9 2 0 0 2 2 2 0 Heavy-metal resistance PAS_6 PF08348.6 KPI39468.1 - 0.077 12.5 0.7 2.8 7.5 0.0 3.1 3 0 0 3 3 3 0 YheO-like PAS domain NdhM PF10664.4 KPI39468.1 - 0.099 12.5 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M SSrecog PF03531.9 KPI39470.1 - 1.5e-47 161.8 6.3 5.2e-23 81.5 0.1 3.4 2 1 1 3 3 3 2 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KPI39470.1 - 6.2e-27 93.4 0.0 9.8e-26 89.5 0.0 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like HAND PF09110.6 KPI39470.1 - 8.2 6.8 10.2 0.21 11.9 1.2 2.5 3 0 0 3 3 3 0 HAND Aldolase_II PF00596.16 KPI39472.1 - 4e-40 137.3 1.9 1.1e-39 136.0 1.3 1.6 2 0 0 2 2 2 1 Class II Aldolase and Adducin N-terminal domain DUF3148 PF11347.3 KPI39472.1 - 0.075 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) Pyr_redox_3 PF13738.1 KPI39473.1 - 6e-20 72.1 0.0 1.8e-19 70.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI39473.1 - 4.8e-08 31.6 0.0 1e-07 30.5 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KPI39473.1 - 1.6e-06 27.2 0.0 3.7e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KPI39473.1 - 4.7e-06 26.4 0.2 5.4e-05 23.0 0.1 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KPI39473.1 - 2.4e-05 24.2 0.0 4.6e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI39473.1 - 0.00013 21.1 0.0 0.0019 17.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 KPI39473.1 - 0.00093 19.1 0.0 0.0055 16.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KPI39473.1 - 0.021 13.3 0.0 1.3 7.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 KPI39473.1 - 0.085 11.7 0.0 0.16 10.8 0.0 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein HET PF06985.6 KPI39474.1 - 3.8e-30 104.8 2.2 6e-30 104.2 1.5 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box PF00646.28 KPI39475.1 - 0.0021 17.6 2.1 0.62 9.7 0.0 2.9 3 0 0 3 3 3 2 F-box domain Zip PF02535.17 KPI39476.1 - 1.5e-16 60.2 2.1 1.8e-16 60.0 1.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4271 PF14093.1 KPI39476.1 - 0.077 12.6 0.4 0.11 12.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) Oxidored_FMN PF00724.15 KPI39477.1 - 1.5e-45 155.7 0.0 3.9e-44 151.0 0.0 2.1 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PSP PF04046.11 KPI39478.1 - 0.064 12.6 0.1 0.41 10.0 0.0 2.1 2 0 0 2 2 2 0 PSP Med13_C PF06333.7 KPI39479.1 - 4.1e-60 203.4 0.0 7.5e-60 202.6 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Glyco_transf_28 PF03033.15 KPI39480.1 - 1.7e-15 57.0 0.0 8.8e-15 54.6 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.11 KPI39480.1 - 6.7e-07 29.1 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.13 KPI39480.1 - 6.4e-05 21.6 0.0 0.0001 21.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 KPI39480.1 - 0.033 14.3 0.0 1.3 9.1 0.0 3.2 3 0 0 3 3 3 0 ATG C terminal domain FAD_binding_1 PF00667.15 KPI39481.1 - 2.2e-58 197.2 0.0 4.7e-58 196.2 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 KPI39481.1 - 2.5e-12 47.3 0.0 8.2e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 KPI39481.1 - 2.7e-08 33.8 0.1 5.5e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 KPI39481.1 - 0.00018 21.4 0.1 0.00087 19.2 0.0 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain POR_N PF01855.14 KPI39481.1 - 0.0096 15.4 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Ufm1 PF03671.9 KPI39482.1 - 0.043 13.5 0.1 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin fold modifier 1 protein RNase_PH PF01138.16 KPI39482.1 - 0.091 13.0 0.2 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 SOG2 PF10428.4 KPI39482.1 - 3.6 6.1 16.3 5.2 5.6 11.1 1.4 1 1 0 1 1 1 0 RAM signalling pathway protein HMG_box PF00505.14 KPI39483.1 - 1.4e-06 28.5 0.4 2.8e-06 27.4 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box AKNA PF12443.3 KPI39483.1 - 0.011 15.7 0.1 0.032 14.2 0.1 1.9 1 0 0 1 1 1 0 AT-hook-containing transcription factor Coiled-coil_56 PF09813.4 KPI39483.1 - 0.031 14.2 3.6 0.25 11.3 0.5 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 56 DUF3987 PF13148.1 KPI39483.1 - 1.8 7.0 6.9 0.081 11.4 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAT PF03417.11 KPI39484.1 - 3.6e-08 33.1 0.0 4e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF387 PF04079.11 KPI39484.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.3 1 1 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) Fungal_trans PF04082.13 KPI39485.1 - 5.5e-18 64.7 0.4 9e-18 64.0 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TraF_2 PF13729.1 KPI39485.1 - 0.0099 14.7 0.1 0.85 8.3 0.0 2.6 2 1 1 3 3 3 2 F plasmid transfer operon, TraF, protein AA_permease_2 PF13520.1 KPI39486.1 - 1.4e-58 198.4 32.7 4.8e-55 186.8 16.1 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 KPI39486.1 - 9.3e-19 67.1 28.8 1.6e-18 66.3 20.0 1.3 1 0 0 1 1 1 1 Amino acid permease SnoaL_2 PF12680.2 KPI39487.1 - 8e-05 22.9 0.0 0.00023 21.4 0.0 1.8 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 KPI39487.1 - 0.0011 18.5 0.0 0.0026 17.3 0.0 1.7 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.13 KPI39487.1 - 0.0013 18.0 0.1 0.071 12.3 0.1 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family TRI12 PF06609.8 KPI39488.1 - 2.9e-77 260.2 25.1 3.5e-77 259.9 17.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI39488.1 - 7.8e-25 87.3 49.1 7.8e-25 87.3 34.0 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Pex24p PF06398.6 KPI39488.1 - 0.088 11.5 4.1 0.12 11.0 1.8 1.8 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Pox_A14 PF05767.7 KPI39488.1 - 0.1 12.5 0.2 0.1 12.5 0.2 3.0 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 HD PF01966.17 KPI39489.1 - 0.0038 17.2 1.1 0.019 15.0 0.8 2.1 1 1 0 1 1 1 1 HD domain Abhydrolase_6 PF12697.2 KPI39490.1 - 6.6e-34 117.7 0.0 1.5e-33 116.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI39490.1 - 1.5e-19 70.4 0.0 2.1e-12 47.1 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI39490.1 - 1.1e-10 41.4 0.0 1.9e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KPI39490.1 - 0.00026 20.7 0.0 0.0011 18.7 0.0 2.1 3 0 0 3 3 3 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 KPI39490.1 - 0.099 12.0 0.0 0.39 10.1 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 KPI39490.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 KPI39490.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) tRNA-synt_1d PF00750.14 KPI39491.1 - 4.1e-80 269.2 10.1 5.6e-44 150.4 4.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 KPI39491.1 - 1.3e-30 105.7 0.1 3.1e-30 104.5 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KPI39491.1 - 0.0001 22.7 0.5 0.00045 20.7 0.0 2.4 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Tcf25 PF04910.9 KPI39491.1 - 0.003 16.5 0.3 0.62 8.9 0.0 2.2 2 0 0 2 2 2 2 Transcriptional repressor TCF25 EcoEI_R_C PF08463.5 KPI39491.1 - 0.024 14.5 1.8 0.051 13.4 1.3 1.5 1 0 0 1 1 1 0 EcoEI R protein C-terminal GFA PF04828.9 KPI39492.1 - 1.7e-09 37.5 1.2 1.7e-09 37.5 0.8 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF4243 PF14027.1 KPI39493.1 - 9.4e-61 206.0 0.1 1.4e-60 205.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Ferritin_2 PF13668.1 KPI39493.1 - 1.4e-22 80.1 14.1 1.8e-14 53.8 1.6 3.1 2 1 1 3 3 3 2 Ferritin-like domain GFA PF04828.9 KPI39494.1 - 2.7e-28 97.7 6.0 1.3e-14 53.8 0.1 2.6 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 KPI39494.1 - 0.00073 19.3 0.5 1.1 9.1 0.1 2.7 2 0 0 2 2 2 2 Nin one binding (NOB1) Zn-ribbon like RNA_POL_M_15KD PF02150.11 KPI39494.1 - 0.56 9.9 12.9 0.61 9.8 0.0 4.4 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit Lyase_1 PF00206.15 KPI39495.1 - 1.1e-25 90.4 0.0 1.5e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Lyase MTH865 PF07747.6 KPI39495.1 - 0.079 12.5 0.1 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 MTH865-like family Sensor PF13796.1 KPI39496.1 - 0.059 12.9 2.1 0.43 10.1 0.3 2.2 2 0 0 2 2 2 0 Putative sensor DUF1191 PF06697.7 KPI39498.1 - 0.00013 20.8 0.1 0.00018 20.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) DUF2976 PF11190.3 KPI39498.1 - 0.013 14.9 0.4 0.023 14.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Myc_target_1 PF15179.1 KPI39498.1 - 0.031 13.8 2.3 0.12 11.9 0.5 2.3 2 0 0 2 2 2 0 Myc target protein 1 Trypan_PARP PF05887.6 KPI39499.1 - 4.7e-06 26.4 14.3 9.2e-06 25.5 9.9 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) F-box PF00646.28 KPI39499.1 - 0.015 14.9 1.0 0.039 13.6 0.7 1.7 1 0 0 1 1 1 0 F-box domain GST_N_3 PF13417.1 KPI39500.1 - 1.7e-22 79.3 0.1 5.1e-18 65.0 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI39500.1 - 4.9e-15 55.2 0.0 1.9e-14 53.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KPI39500.1 - 0.00049 20.2 0.0 0.1 12.7 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KPI39500.1 - 0.022 14.7 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI39500.1 - 0.028 14.3 0.3 0.07 13.0 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 KPI39500.1 - 0.045 13.7 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin adh_short PF00106.20 KPI39501.1 - 7.9e-13 48.6 1.0 9e-12 45.2 0.6 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI39501.1 - 3.9e-10 39.9 1.0 1.2e-09 38.3 0.7 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI39501.1 - 0.01 15.4 0.2 0.044 13.4 0.0 1.9 2 0 0 2 2 2 0 KR domain SnoaL PF07366.7 KPI39502.1 - 3.2e-19 68.7 0.1 3.8e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KPI39502.1 - 1.4e-12 47.9 0.9 2e-12 47.4 0.6 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF3431 PF11913.3 KPI39503.1 - 5.4e-60 202.6 0.2 7.4e-60 202.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Pyridox_oxidase PF01243.15 KPI39506.1 - 1e-06 28.6 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 KPI39506.1 - 0.00039 20.4 0.0 0.025 14.7 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KPI39506.1 - 0.0083 16.6 0.0 0.12 12.9 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KPI39506.1 - 0.062 13.2 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain zf-C3HC4 PF00097.20 KPI39507.1 - 2e-07 30.5 7.0 6e-07 29.0 5.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KPI39507.1 - 2.1e-07 30.6 10.3 3.4e-07 29.9 7.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KPI39507.1 - 1.8e-06 27.8 8.8 3.1e-06 27.0 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KPI39507.1 - 1.7e-05 24.4 1.0 3.7e-05 23.4 0.7 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KPI39507.1 - 5.3e-05 23.0 5.6 0.00012 21.8 3.9 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KPI39507.1 - 0.00047 19.7 4.9 0.00087 18.9 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI39507.1 - 0.00072 19.2 7.8 0.0014 18.2 5.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KPI39507.1 - 0.0057 16.3 3.2 0.0057 16.3 2.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KPI39507.1 - 6 7.0 7.7 16 5.7 5.3 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger MLANA PF14991.1 KPI39508.1 - 0.0023 17.9 0.0 0.0054 16.7 0.0 1.6 2 0 0 2 2 2 1 Protein melan-A SKG6 PF08693.5 KPI39508.1 - 0.0039 16.4 2.4 0.0083 15.4 1.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 KPI39508.1 - 0.0041 16.8 0.9 0.0073 15.9 0.6 1.3 1 0 0 1 1 1 1 Rifin/stevor family EphA2_TM PF14575.1 KPI39508.1 - 0.012 15.9 0.1 0.022 15.1 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF347 PF03988.7 KPI39508.1 - 0.064 13.1 0.2 0.064 13.1 0.1 1.9 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) DUF948 PF06103.6 KPI39508.1 - 0.12 12.2 0.5 0.19 11.5 0.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) ABC_membrane PF00664.18 KPI39509.1 - 8.7e-44 149.9 10.4 1.2e-43 149.4 7.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KPI39509.1 - 6.5e-35 120.4 0.0 1.6e-34 119.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KPI39509.1 - 3e-07 29.9 1.5 4.1e-05 22.9 0.0 2.9 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KPI39509.1 - 0.0012 18.8 0.1 2.1 8.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KPI39509.1 - 0.0016 17.9 0.0 0.0037 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KPI39509.1 - 0.003 17.0 0.0 0.0076 15.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 KPI39509.1 - 0.0046 16.4 0.1 0.039 13.3 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 KPI39509.1 - 0.0064 17.3 0.2 0.021 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KPI39509.1 - 0.0069 16.3 0.2 0.025 14.5 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 KPI39509.1 - 0.0072 15.8 0.3 0.33 10.3 0.1 2.3 2 0 0 2 2 2 1 AAA-like domain AAA PF00004.24 KPI39509.1 - 0.0077 16.4 0.0 0.029 14.5 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KPI39509.1 - 0.01 15.9 0.1 0.035 14.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KPI39509.1 - 0.35 10.7 5.1 0.25 11.2 0.6 2.9 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Rap1_C PF11626.3 KPI39510.1 - 1.4e-16 60.1 0.1 8.4e-16 57.6 0.1 2.2 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 KPI39510.1 - 2.2e-15 56.1 0.5 3.3e-14 52.4 0.2 2.5 2 0 0 2 2 2 1 Rap1 Myb domain GATA PF00320.22 KPI39510.1 - 3.4e-06 26.2 6.2 3.4e-06 26.2 4.3 2.0 2 0 0 2 2 2 1 GATA zinc finger Rap1-DNA-bind PF09197.5 KPI39510.1 - 3.1e-05 24.4 1.0 0.00014 22.3 0.0 2.6 2 0 0 2 2 2 1 Rap1, DNA-binding Herpes_TK_C PF08465.5 KPI39510.1 - 0.084 12.3 0.7 0.66 9.5 0.1 2.4 2 0 0 2 2 2 0 Thymidine kinase from Herpesvirus C-terminal zf-C3HC4_2 PF13923.1 KPI39510.1 - 0.3 11.1 0.3 0.52 10.3 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ABM PF03992.11 KPI39511.1 - 0.0039 17.1 0.5 0.93 9.5 0.1 2.9 3 0 0 3 3 3 2 Antibiotic biosynthesis monooxygenase Glyco_hydro_cc PF11790.3 KPI39512.1 - 2.4e-58 197.4 0.3 2.9e-58 197.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF1929 PF09118.6 KPI39513.1 - 0.12 12.4 0.3 0.85 9.7 0.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF1929) WD40 PF00400.27 KPI39514.1 - 1.3e-54 180.1 21.9 4.5e-10 39.0 0.5 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KPI39514.1 - 3.3e-13 49.1 0.5 5.6e-13 48.3 0.3 1.4 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KPI39514.1 - 1.1e-06 27.0 7.9 0.34 9.0 0.1 5.2 1 1 4 5 5 5 3 Nucleoporin Nup120/160 F-box PF00646.28 KPI39514.1 - 5.5e-05 22.7 1.7 0.00012 21.6 1.2 1.6 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 KPI39514.1 - 0.0017 17.1 0.1 0.1 11.3 0.0 2.9 2 2 1 3 3 3 1 Nup133 N terminal like PQQ_2 PF13360.1 KPI39514.1 - 0.0089 15.5 1.7 0.59 9.5 0.4 3.1 2 1 1 3 3 3 1 PQQ-like domain PyrBI_leader PF08052.6 KPI39514.1 - 0.13 12.0 0.3 0.25 11.1 0.2 1.4 1 0 0 1 1 1 0 PyrBI operon leader peptide PQQ_3 PF13570.1 KPI39514.1 - 0.54 10.6 9.3 57 4.1 0.0 5.9 5 2 3 8 8 8 0 PQQ-like domain TFIIE_alpha PF02002.12 KPI39515.1 - 1.4e-06 27.7 0.2 1.4e-06 27.7 0.2 1.7 2 0 0 2 2 2 1 TFIIE alpha subunit zf-FPG_IleRS PF06827.9 KPI39515.1 - 0.0061 16.1 0.5 0.013 15.1 0.3 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS Rubredoxin PF00301.15 KPI39515.1 - 0.78 9.6 0.0 0.78 9.6 0.0 2.6 2 0 0 2 2 2 0 Rubredoxin Med7 PF05983.6 KPI39516.1 - 5.7e-33 113.9 0.0 7.7e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 MED7 protein DUF3635 PF12330.3 KPI39517.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3635) NUC153 PF08159.7 KPI39519.1 - 2.7e-10 39.6 3.6 5.1e-10 38.7 0.9 2.4 2 0 0 2 2 2 1 NUC153 domain WD40 PF00400.27 KPI39519.1 - 0.1 12.4 0.3 73 3.4 0.0 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat Fungal_trans PF04082.13 KPI39520.1 - 1.2e-15 57.0 0.9 1.8e-15 56.5 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cpn60_TCP1 PF00118.19 KPI39521.1 - 1.8e-117 392.9 3.2 3.4e-117 392.0 2.2 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family FAM176 PF14851.1 KPI39521.1 - 2.3 7.8 5.4 3.8 7.1 2.9 1.9 2 0 0 2 2 2 0 FAM176 family Cupin_2 PF07883.6 KPI39522.1 - 1.3e-12 47.0 0.8 1.7e-08 33.8 0.0 2.7 3 0 0 3 3 3 2 Cupin domain DUF1255 PF06865.6 KPI39522.1 - 0.0029 17.8 0.0 0.0067 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1255) AraC_binding PF02311.14 KPI39522.1 - 0.0041 16.7 0.0 0.022 14.4 0.0 2.0 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.7 KPI39522.1 - 0.0099 15.2 0.1 1.9 7.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_1 PF00190.17 KPI39522.1 - 0.042 13.2 0.0 0.63 9.4 0.0 2.4 1 1 0 1 1 1 0 Cupin Cupin_4 PF08007.7 KPI39522.1 - 0.15 11.2 1.4 0.15 11.2 0.1 1.6 2 0 0 2 2 2 0 Cupin superfamily protein PSI_PsaF PF02507.10 KPI39523.1 - 0.062 12.8 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III TSGP1 PF07771.6 KPI39523.1 - 0.16 11.8 1.2 2.2 8.1 0.0 2.3 1 1 1 2 2 2 0 Tick salivary peptide group 1 Bromodomain PF00439.20 KPI39524.1 - 3e-20 71.9 0.6 8.5e-20 70.4 0.4 1.8 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 KPI39524.1 - 1.3e-05 24.8 0.0 3.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated DAGAT PF03982.8 KPI39525.1 - 2.4e-94 315.3 0.0 3.1e-94 314.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Filament PF00038.16 KPI39526.1 - 5.3e-05 22.8 1.7 7.2e-05 22.4 1.2 1.2 1 0 0 1 1 1 1 Intermediate filament protein FCH PF00611.18 KPI39526.1 - 0.00046 20.3 0.0 0.00082 19.5 0.0 1.6 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain LXG PF04740.7 KPI39526.1 - 0.032 14.0 0.5 2 8.1 0.1 2.0 1 1 0 1 1 1 0 LXG domain of WXG superfamily AAA_13 PF13166.1 KPI39526.1 - 0.033 12.6 0.5 0.036 12.5 0.3 1.0 1 0 0 1 1 1 0 AAA domain Apolipoprotein PF01442.13 KPI39526.1 - 0.053 13.0 4.7 0.14 11.6 3.2 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Cas_Cas1 PF01867.11 KPI39526.1 - 0.098 11.7 0.1 0.16 11.0 0.0 1.3 1 1 0 1 1 1 0 CRISPR associated protein Cas1 TMF_TATA_bd PF12325.3 KPI39526.1 - 0.63 9.7 3.3 2.4 7.9 0.1 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ISG65-75 PF11727.3 KPI39526.1 - 1.8 7.5 4.4 14 4.6 3.0 1.9 1 1 0 1 1 1 0 Invariant surface glycoprotein F-box PF00646.28 KPI39527.1 - 0.0039 16.7 0.0 0.0089 15.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KPI39527.1 - 0.056 13.1 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 F-box-like HMG_box_5 PF14887.1 KPI39527.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 CFEM PF05730.6 KPI39528.1 - 3.4e-05 23.5 3.8 3.4e-05 23.5 2.7 1.8 2 1 0 2 2 2 1 CFEM domain Catalase PF00199.14 KPI39529.1 - 8.3e-113 376.9 0.0 1.1e-112 376.5 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KPI39529.1 - 1.2e-11 44.2 0.1 2.9e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Chromo_shadow PF01393.14 KPI39531.1 - 0.12 12.1 0.0 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Chromo shadow domain PAT1 PF09770.4 KPI39532.1 - 0.43 8.7 10.5 0.43 8.7 7.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pirin PF02678.11 KPI39533.1 - 8.4e-24 83.5 2.5 3.4e-23 81.5 1.7 1.9 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 KPI39533.1 - 2e-06 27.1 3.6 4.1e-05 22.9 0.7 3.1 2 1 0 2 2 2 2 Cupin domain Hydantoinase_A PF01968.13 KPI39534.1 - 1.2e-87 293.6 6.0 1e-86 290.6 2.1 2.2 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydantoinase_B PF02538.9 KPI39534.1 - 4.3e-66 223.2 0.0 8e-66 222.3 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydant_A_N PF05378.8 KPI39534.1 - 1.3e-47 161.5 5.4 3.6e-46 156.8 0.0 3.0 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 KPI39534.1 - 0.0072 14.7 0.5 0.48 8.6 0.0 2.4 2 0 0 2 2 2 2 MutL protein FtsA PF14450.1 KPI39534.1 - 0.0087 15.8 1.6 0.74 9.6 0.0 3.0 2 1 0 2 2 2 1 Cell division protein FtsA AhpC-TSA PF00578.16 KPI39535.1 - 4.7e-33 113.5 0.0 6.9e-33 112.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KPI39535.1 - 2.3e-14 53.1 0.0 3.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KPI39535.1 - 1.4e-12 46.9 0.2 2.5e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin CFEM PF05730.6 KPI39536.1 - 1.7e-08 34.1 7.2 3e-08 33.3 5.0 1.4 1 0 0 1 1 1 1 CFEM domain DUF935 PF06074.7 KPI39537.1 - 0.48 9.0 6.2 1.2 7.7 4.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF935) DUF4200 PF13863.1 KPI39537.1 - 0.95 9.4 8.8 0.88 9.5 4.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) PYC_OADA PF02436.13 KPI39538.1 - 5.8e-64 215.1 0.0 9.6e-64 214.4 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_lipoyl PF00364.17 KPI39538.1 - 4.8e-19 67.7 4.4 1e-18 66.7 3.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KPI39538.1 - 3.6e-13 48.9 1.2 1.1e-08 34.5 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 KPI39538.1 - 4.5e-06 26.9 0.2 0.00027 21.2 0.1 3.0 2 1 1 3 3 3 2 HlyD family secretion protein HlyD_2 PF12700.2 KPI39538.1 - 1.8e-05 24.0 3.6 0.02 14.0 0.0 2.5 2 1 1 3 3 3 2 HlyD family secretion protein HlyD PF00529.15 KPI39538.1 - 2.3e-05 23.8 0.5 0.0018 17.6 0.0 2.5 3 0 0 3 3 3 1 HlyD family secretion protein RnfC_N PF13375.1 KPI39538.1 - 0.011 15.4 2.2 0.037 13.7 1.5 2.0 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.4 KPI39538.1 - 0.013 15.1 1.4 0.016 14.8 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) PYNP_C PF07831.8 KPI39538.1 - 0.02 14.3 0.2 0.18 11.2 0.0 2.3 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain GCV_H PF01597.14 KPI39538.1 - 0.038 13.6 3.3 0.18 11.4 0.7 2.4 1 1 1 2 2 2 0 Glycine cleavage H-protein NQRA PF05896.6 KPI39538.1 - 0.1 11.7 0.1 0.18 10.9 0.1 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) FAD_binding_3 PF01494.14 KPI39539.1 - 5.2e-39 134.2 0.0 7.1e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI39539.1 - 3.4e-06 26.2 0.0 0.034 13.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KPI39539.1 - 4.6e-05 23.7 0.1 0.014 15.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI39539.1 - 6.2e-05 22.9 0.0 0.00033 20.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI39539.1 - 0.00014 21.7 0.1 0.00052 19.9 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KPI39539.1 - 0.00017 20.6 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KPI39539.1 - 0.0008 17.9 0.2 0.013 14.0 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein PRONE PF03759.8 KPI39539.1 - 0.0026 16.3 0.0 0.0044 15.6 0.0 1.3 1 0 0 1 1 1 1 PRONE (Plant-specific Rop nucleotide exchanger) Thi4 PF01946.12 KPI39539.1 - 0.0029 16.7 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KPI39539.1 - 0.0063 15.4 0.7 0.048 12.5 0.3 2.2 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 KPI39539.1 - 0.0096 16.0 0.1 0.045 13.8 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 KPI39539.1 - 0.017 13.3 0.0 0.028 12.5 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.17 KPI39539.1 - 0.04 12.7 0.0 0.098 11.4 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 KPI39539.1 - 0.054 12.8 0.0 5.3 6.3 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KPI39539.1 - 0.085 12.5 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mito_fiss_reg PF05308.6 KPI39540.1 - 0.011 15.0 0.2 0.044 13.1 0.1 2.0 1 0 0 1 1 1 0 Mitochondrial fission regulator Shadoo PF14999.1 KPI39540.1 - 0.47 10.3 13.4 3.6 7.4 1.3 3.6 3 1 0 3 3 3 0 Shadow of prion protein, neuroprotective FAD-SLDH PF12318.3 KPI39541.1 - 0.35 10.5 2.0 1 9.0 1.4 1.7 1 1 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Aldedh PF00171.17 KPI39542.1 - 4.9e-163 542.7 0.1 5.5e-163 542.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KPI39542.1 - 0.017 13.8 0.0 0.026 13.2 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Glyoxalase_2 PF12681.2 KPI39543.1 - 1.3e-10 41.8 0.0 7.8e-09 36.1 0.0 2.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KPI39543.1 - 1.4e-10 41.2 0.0 6.2e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KPI39543.1 - 0.00056 19.8 0.0 0.0014 18.6 0.0 1.7 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3081 PF11280.3 KPI39543.1 - 0.019 14.4 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) Fe-ADH PF00465.14 KPI39544.1 - 5.7e-75 252.2 1.0 6.5e-75 252.0 0.7 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KPI39544.1 - 5.7e-18 65.1 0.2 8.3e-18 64.5 0.1 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF1967 PF09269.6 KPI39544.1 - 0.19 11.3 0.1 0.47 10.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) CW_binding_2 PF04122.7 KPI39544.1 - 0.27 11.4 1.5 5.1 7.3 0.1 2.7 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 SKG6 PF08693.5 KPI39545.1 - 0.0035 16.6 0.1 0.0035 16.6 0.0 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain CcmD PF04995.9 KPI39545.1 - 0.45 10.2 2.9 0.79 9.5 2.0 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Abhydrolase_1 PF00561.15 KPI39546.1 - 3.2e-22 79.2 0.0 4.3e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 KPI39546.1 - 3.2e-14 52.6 0.0 6.6e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 KPI39546.1 - 3.6e-10 40.1 1.0 1e-09 38.6 0.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI39546.1 - 0.00047 19.9 0.0 0.0017 18.1 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI39547.1 - 1.6e-18 66.8 0.6 3.1e-18 65.9 0.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI39547.1 - 2.3e-06 27.6 0.3 0.0022 17.8 0.5 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KPI39547.1 - 0.0018 18.1 0.0 0.0048 16.7 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.13 KPI39547.1 - 0.002 17.4 0.0 0.0053 16.0 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.15 KPI39547.1 - 0.097 12.0 0.9 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 Putative esterase DEAD PF00270.24 KPI39548.1 - 1.1e-40 138.8 0.0 2.9e-39 134.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI39548.1 - 2e-25 88.4 0.9 4.4e-25 87.3 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 KPI39548.1 - 0.00011 22.4 2.6 0.00037 20.7 1.8 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) ResIII PF04851.10 KPI39548.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AhpC-TSA PF00578.16 KPI39549.1 - 2.6e-25 88.5 0.0 3.4e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KPI39549.1 - 3.2e-17 62.4 0.0 8e-17 61.1 0.0 1.6 1 1 0 1 1 1 1 Redoxin DUF899 PF05988.7 KPI39549.1 - 2e-06 27.3 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA_2 PF13911.1 KPI39549.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme efThoc1 PF11957.3 KPI39550.1 - 8.6e-124 413.7 0.0 1.1e-123 413.3 0.0 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor FAM180 PF15173.1 KPI39550.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 FAM180 family DUF313 PF03754.8 KPI39550.1 - 0.16 11.8 0.2 6.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF313) GST_N_2 PF13409.1 KPI39552.1 - 3.5e-18 65.3 0.0 6.7e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KPI39552.1 - 4.5e-10 39.2 0.0 1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KPI39552.1 - 0.00014 22.0 0.0 0.28 11.4 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KPI39552.1 - 0.0021 18.5 0.0 0.0039 17.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KPI39552.1 - 0.006 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain UbiA PF01040.13 KPI39554.1 - 2.8e-20 72.6 14.6 2.9e-12 46.3 7.0 2.4 2 1 0 2 2 2 2 UbiA prenyltransferase family CENP-U PF13097.1 KPI39554.1 - 1 9.2 4.7 1.6 8.6 3.3 1.2 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit SOBP PF15279.1 KPI39554.1 - 8 6.7 10.4 15 5.8 7.2 1.5 1 1 0 1 1 1 0 Sine oculis-binding protein Enolase_C PF00113.17 KPI39556.1 - 1.1e-99 333.1 0.3 1.3e-99 332.9 0.2 1.0 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain MR_MLE_C PF13378.1 KPI39556.1 - 0.0013 18.6 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 KPI39556.1 - 0.045 12.6 0.7 0.12 11.2 0.4 1.7 1 1 1 2 2 2 0 Methylaspartate ammonia-lyase C-terminus Fungal_trans PF04082.13 KPI39557.1 - 9.9e-09 34.4 0.2 1.7e-08 33.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI39557.1 - 2.2e-05 24.2 6.4 4e-05 23.4 4.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KPI39558.1 - 2.9e-35 121.6 64.3 1.2e-29 103.2 36.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily CAP PF00188.21 KPI39559.1 - 5.1e-06 26.9 0.9 6.4e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family DUF605 PF04652.11 KPI39559.1 - 0.41 10.0 13.1 0.47 9.7 9.1 1.1 1 0 0 1 1 1 0 Vta1 like p450 PF00067.17 KPI39561.1 - 1e-06 27.5 0.2 2.5e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 E1-E2_ATPase PF00122.15 KPI39562.1 - 3.3e-37 127.7 0.2 2.2e-26 92.2 0.0 2.5 1 1 1 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.16 KPI39562.1 - 3.5e-33 114.6 3.8 3.5e-33 114.6 2.6 2.6 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KPI39562.1 - 5.5e-26 92.3 0.0 1.4e-25 91.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KPI39562.1 - 5.6e-15 56.0 0.0 2.3e-14 54.0 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KPI39562.1 - 4.5e-14 52.1 0.0 8.5e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KPI39562.1 - 5.7e-10 38.5 0.0 1.4e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cep57_CLD_2 PF14197.1 KPI39563.1 - 0.42 10.5 8.5 0.022 14.6 0.6 2.9 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Asp_Glu_race PF01177.17 KPI39564.1 - 4.5e-16 59.4 0.2 5.8e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase CDC45 PF02724.9 KPI39564.1 - 0.11 10.5 0.0 0.14 10.1 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-RING_2 PF13639.1 KPI39565.1 - 0.0025 17.5 6.3 0.0044 16.8 4.4 1.4 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 KPI39565.1 - 0.0034 17.3 2.2 0.019 14.9 2.3 1.6 2 0 0 2 2 2 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 KPI39565.1 - 0.09 12.4 4.9 0.16 11.6 3.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_32N PF00251.15 KPI39566.1 - 2.4e-36 125.6 0.1 3.9e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KPI39566.1 - 6.2e-11 42.5 0.0 1.4e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 KPI39566.1 - 1.2 9.2 4.5 12 6.2 0.2 3.2 2 0 0 2 2 2 0 BNR/Asp-box repeat Pkinase PF00069.20 KPI39567.1 - 1.5e-54 184.9 0.0 4.5e-54 183.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI39567.1 - 4.1e-30 104.7 0.0 6.1e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI39567.1 - 0.046 12.6 0.1 0.098 11.5 0.0 1.5 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 KPI39567.1 - 0.12 12.0 0.1 0.35 10.5 0.0 1.6 1 1 0 2 2 2 0 Phosphotransferase enzyme family DMRL_synthase PF00885.14 KPI39568.1 - 2.4e-39 134.2 0.2 3.9e-21 75.2 0.0 2.1 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase ADK PF00406.17 KPI39569.1 - 1e-44 152.0 0.0 1.3e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 KPI39569.1 - 4.3e-12 46.4 0.0 6.6e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KPI39569.1 - 7e-07 30.0 0.0 9.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KPI39569.1 - 3.8e-06 26.8 0.0 9.1e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KPI39569.1 - 0.00063 19.1 0.2 0.29 10.5 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_19 PF13245.1 KPI39569.1 - 0.067 12.9 0.0 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 Part of AAA domain C2 PF00168.25 KPI39570.1 - 5.9e-19 67.7 0.0 1.8e-11 43.7 0.0 2.7 2 0 0 2 2 2 2 C2 domain DUF2183 PF09949.4 KPI39570.1 - 0.056 13.3 0.0 0.31 11.0 0.0 2.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Claudin_2 PF13903.1 KPI39570.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction COesterase PF00135.23 KPI39571.1 - 2.6e-66 224.4 0.0 2.1e-65 221.4 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI39571.1 - 1.2e-06 28.2 0.0 8.2e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold adh_short PF00106.20 KPI39572.1 - 1.8e-15 57.2 0.1 2.8e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI39572.1 - 2.1e-07 30.7 0.1 4.2e-07 29.8 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI39572.1 - 0.00086 18.8 0.2 0.0016 17.9 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI39572.1 - 0.036 14.0 0.5 0.37 10.7 0.3 2.2 1 1 0 1 1 1 0 NADH(P)-binding DUF3025 PF11227.3 KPI39572.1 - 0.04 13.4 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) CTP_transf_1 PF01148.15 KPI39573.1 - 6.2e-06 26.0 2.8 6.2e-06 26.0 2.0 3.6 4 0 0 4 4 4 2 Cytidylyltransferase family DUF1352 PF07086.7 KPI39573.1 - 0.019 14.6 0.9 7.7 6.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1352) AAA_26 PF13500.1 KPI39574.1 - 1e-35 123.1 0.0 3.3e-35 121.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain Aminotran_3 PF00202.16 KPI39574.1 - 7.4e-20 71.0 0.0 1.1e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III CbiA PF01656.18 KPI39574.1 - 0.019 14.3 0.0 0.04 13.3 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KPI39574.1 - 0.031 14.2 0.0 0.09 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain UPF0066 PF01980.11 KPI39575.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0066 ABC_membrane PF00664.18 KPI39577.1 - 1.6e-11 44.1 3.4 1.6e-11 44.1 2.3 3.4 4 1 1 5 5 5 1 ABC transporter transmembrane region ABC_tran PF00005.22 KPI39577.1 - 1.6e-06 28.4 0.0 3.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 KPI39577.1 - 0.0016 18.8 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KPI39577.1 - 0.014 14.2 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 KPI39577.1 - 0.038 13.7 0.2 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_25 PF13481.1 KPI39577.1 - 0.044 13.1 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KPI39577.1 - 0.049 13.2 0.1 0.096 12.3 0.1 1.5 1 0 0 1 1 1 0 NACHT domain DUF490 PF04357.8 KPI39577.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF490) DUF2075 PF09848.4 KPI39577.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 KPI39577.1 - 0.26 10.3 0.6 3.6 6.6 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin Lactamase_B_2 PF12706.2 KPI39579.1 - 9.5e-06 25.2 1.0 1.4e-05 24.7 0.7 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KPI39579.1 - 0.0029 17.2 9.0 0.014 15.0 6.3 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 KPI39579.1 - 0.072 12.7 0.9 0.17 11.6 0.1 1.8 2 1 0 2 2 2 0 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KPI39581.1 - 3.5e-10 39.8 1.4 6.1e-08 32.5 0.1 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI39581.1 - 5.9e-06 25.9 0.1 1e-05 25.2 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KPI39581.1 - 0.048 13.3 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Pkinase PF00069.20 KPI39582.1 - 3.6e-65 219.7 0.0 5.6e-65 219.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI39582.1 - 8.1e-44 149.6 0.0 1.5e-43 148.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI39582.1 - 1.5e-09 37.2 0.0 4.2e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KPI39582.1 - 0.007 16.1 3.2 0.32 10.6 0.1 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KPI39582.1 - 0.031 13.3 0.0 0.067 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.17 KPI39583.1 - 3e-115 385.3 0.0 2.9e-69 233.7 0.0 3.0 2 1 0 2 2 2 2 Cytochrome P450 Ribosomal_S17 PF00366.15 KPI39584.1 - 2.3e-29 101.2 0.4 3.5e-29 100.6 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 IMS PF00817.15 KPI39585.1 - 4.5e-43 146.6 0.8 9.6e-43 145.5 0.5 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KPI39585.1 - 7.4e-14 51.7 0.0 1.5e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KPI39585.1 - 4.3e-07 29.6 0.0 1.3e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif DUF3129 PF11327.3 KPI39586.1 - 1.3e-64 217.3 10.2 1.6e-64 217.0 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Fungal_trans_2 PF11951.3 KPI39587.1 - 1.5e-68 231.1 0.0 3e-68 230.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI39587.1 - 1.8e-07 30.9 8.7 3e-07 30.2 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Barstar PF01337.13 KPI39588.1 - 0.0054 16.5 0.2 0.011 15.5 0.2 1.5 1 0 0 1 1 1 1 Barstar (barnase inhibitor) DUF1657 PF07870.6 KPI39588.1 - 0.096 12.3 0.4 0.44 10.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) Erythro-docking PF09277.6 KPI39588.1 - 0.17 11.6 0.4 0.17 11.6 0.3 2.4 2 0 0 2 2 2 0 Erythronolide synthase, docking ADH_zinc_N PF00107.21 KPI39589.1 - 3.5e-27 94.5 1.9 3.5e-27 94.5 1.3 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI39589.1 - 4.4e-23 81.1 1.8 1.3e-22 79.6 1.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KPI39589.1 - 1.1e-05 26.3 0.1 2.1e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 KPI39589.1 - 0.0014 18.5 0.6 0.0018 18.1 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ADH_N_assoc PF13823.1 KPI39589.1 - 0.0067 16.0 0.7 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Shikimate_DH PF01488.15 KPI39589.1 - 0.0095 16.0 0.1 0.016 15.2 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 KPI39589.1 - 0.011 14.7 0.9 0.023 13.6 0.6 1.5 1 1 1 2 2 2 0 Saccharopine dehydrogenase CPSase_L_chain PF00289.17 KPI39589.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain TrkA_N PF02254.13 KPI39589.1 - 0.029 14.3 0.1 0.053 13.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.1 KPI39589.1 - 0.031 14.3 0.1 0.056 13.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 KPI39589.1 - 0.039 13.0 0.1 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KPI39589.1 - 0.13 12.5 1.4 0.23 11.7 1.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 KPI39589.1 - 2.3 8.6 5.5 3.3 8.1 0.3 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase LigD_N PF13298.1 KPI39590.1 - 2.4e-25 88.6 0.0 9.5e-25 86.7 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase Ligase (LigD) DUF4551 PF15087.1 KPI39590.1 - 9.6 4.4 9.5 15 3.7 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ThuA PF06283.6 KPI39591.1 - 7.6e-43 146.7 0.1 8.8e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation DUF1355 PF07090.6 KPI39591.1 - 0.017 14.5 0.0 0.069 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1355) Translin PF01997.11 KPI39592.1 - 3.8e-51 173.5 0.0 4.4e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Translin family HVSL PF09749.4 KPI39592.1 - 0.08 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein KNOX1 PF03790.8 KPI39592.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 KNOX1 domain MFS_1 PF07690.11 KPI39593.1 - 5.2e-19 68.1 27.0 5.2e-19 68.1 18.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily CitMHS PF03600.11 KPI39593.1 - 0.0049 15.5 5.8 0.11 11.0 3.9 2.3 1 1 0 1 1 1 1 Citrate transporter YrhC PF14143.1 KPI39593.1 - 0.72 9.8 0.0 0.72 9.8 0.0 2.5 3 0 0 3 3 3 0 YrhC-like protein Pro_isomerase PF00160.16 KPI39594.1 - 6.6e-44 149.8 0.4 9e-44 149.4 0.3 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF347 PF03988.7 KPI39594.1 - 0.065 13.1 1.9 0.16 11.8 0.0 2.6 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) DUF4064 PF13273.1 KPI39594.1 - 0.093 12.8 0.3 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) FixQ PF05545.6 KPI39594.1 - 2.4 7.8 6.4 1.1 8.9 0.2 2.2 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ GATA PF00320.22 KPI39595.1 - 8.5e-15 53.8 5.2 1.6e-14 52.9 3.6 1.5 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 KPI39595.1 - 0.23 11.4 1.9 0.48 10.4 1.3 1.5 1 0 0 1 1 1 0 zinc-finger CorA PF01544.13 KPI39595.1 - 0.34 9.9 1.4 0.49 9.3 1.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ABC_tran PF00005.22 KPI39596.1 - 9.6e-47 158.7 0.4 5.1e-22 78.6 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 KPI39596.1 - 1.9e-18 66.0 6.4 1.9e-18 66.0 4.4 3.8 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.1 KPI39596.1 - 9.3e-17 61.9 1.7 0.0015 18.5 0.0 4.7 5 0 0 5 5 4 3 AAA domain SMC_N PF02463.14 KPI39596.1 - 1.2e-10 40.9 0.4 0.02 14.1 0.0 4.6 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KPI39596.1 - 2e-08 35.1 0.1 0.013 16.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KPI39596.1 - 2.3e-06 27.0 0.7 0.078 12.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 KPI39596.1 - 5.5e-06 25.6 5.0 0.29 10.1 0.0 4.6 4 2 0 4 4 4 2 AAA ATPase domain Miro PF08477.8 KPI39596.1 - 6.8e-06 26.5 2.1 0.013 15.9 0.0 3.3 4 0 0 4 4 2 2 Miro-like protein AAA_23 PF13476.1 KPI39596.1 - 1e-05 25.9 14.2 0.0032 17.8 0.0 4.7 5 0 0 5 5 5 2 AAA domain DUF258 PF03193.11 KPI39596.1 - 1.3e-05 24.3 0.1 0.025 13.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KPI39596.1 - 1.9e-05 24.8 0.1 0.3 11.2 0.0 3.4 3 2 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 KPI39596.1 - 2.7e-05 24.1 0.0 0.051 13.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 KPI39596.1 - 5.8e-05 22.8 0.2 0.23 11.1 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KPI39596.1 - 9e-05 22.5 0.7 0.056 13.4 0.1 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_18 PF13238.1 KPI39596.1 - 9.3e-05 22.7 4.2 0.26 11.6 0.0 3.6 5 0 0 5 5 2 2 AAA domain AAA_33 PF13671.1 KPI39596.1 - 0.00038 20.3 0.1 0.79 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KPI39596.1 - 0.00079 19.1 0.4 0.6 9.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 KPI39596.1 - 0.0016 18.6 0.1 1.6 8.9 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KPI39596.1 - 0.002 18.0 0.8 5 7.0 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_30 PF13604.1 KPI39596.1 - 0.002 17.7 0.0 0.12 11.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KPI39596.1 - 0.0021 18.0 4.6 0.16 11.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 KPI39596.1 - 0.0021 17.4 0.0 1.4 8.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 KPI39596.1 - 0.0044 15.8 2.8 1.4 7.6 0.0 3.1 3 0 0 3 3 3 2 ArgK protein RNA_helicase PF00910.17 KPI39596.1 - 0.0053 16.9 0.0 2.8 8.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.18 KPI39596.1 - 0.0055 16.5 6.0 0.94 9.2 0.0 3.7 4 0 0 4 4 3 1 Dynamin family Zeta_toxin PF06414.7 KPI39596.1 - 0.0073 15.4 0.8 0.72 8.9 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_5 PF07728.9 KPI39596.1 - 0.0086 15.8 0.2 6.6 6.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 KPI39596.1 - 0.0087 15.7 0.1 1.6 8.4 0.1 2.7 2 0 0 2 2 2 1 NTPase AAA_10 PF12846.2 KPI39596.1 - 0.0088 15.5 0.4 3.2 7.1 0.0 2.9 2 1 0 2 2 2 1 AAA-like domain ATP-synt_ab PF00006.20 KPI39596.1 - 0.019 14.4 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 KPI39596.1 - 0.022 14.1 0.8 2.6 7.4 0.5 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KPI39596.1 - 0.024 14.4 0.1 1.6 8.4 0.0 3.0 3 0 0 3 3 3 0 Part of AAA domain SbcCD_C PF13558.1 KPI39596.1 - 0.025 14.4 0.2 12 5.8 0.1 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.1 KPI39596.1 - 0.026 14.0 0.1 5.6 6.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KPI39596.1 - 0.041 12.7 0.0 4.5 6.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 KPI39596.1 - 0.091 12.2 0.1 9.2 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3824 PF12868.2 KPI39596.1 - 0.82 10.6 3.6 0.53 11.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) DUF87 PF01935.12 KPI39596.1 - 3.1 7.5 11.2 2.3 7.9 0.0 3.9 5 0 0 5 5 4 0 Domain of unknown function DUF87 Ank_2 PF12796.2 KPI39597.1 - 4e-31 107.1 0.0 2.7e-17 62.8 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KPI39597.1 - 1.3e-26 90.9 0.0 7e-07 28.7 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KPI39597.1 - 3e-26 91.2 0.0 9.9e-11 41.8 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KPI39597.1 - 1.2e-20 73.0 0.0 1.6e-06 28.1 0.0 5.8 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI39597.1 - 7.6e-18 62.8 0.0 0.0023 18.0 0.0 6.7 6 1 1 7 7 7 4 Ankyrin repeat AAA_10 PF12846.2 KPI39597.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Pkinase PF00069.20 KPI39598.1 - 7.6e-79 264.5 0.0 1.1e-78 264.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI39598.1 - 5.8e-40 136.9 0.0 8.1e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KPI39598.1 - 5.5e-17 61.6 0.2 1.1e-16 60.7 0.1 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KPI39598.1 - 2e-09 36.8 0.0 2.6e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 KPI39598.1 - 0.013 14.3 0.0 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 KPI39598.1 - 0.023 14.4 0.0 0.076 12.7 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KPI39598.1 - 0.049 12.6 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.20 KPI39599.1 - 1.9e-17 63.6 0.3 2.7e-17 63.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI39599.1 - 3.1e-09 36.9 0.3 4e-09 36.5 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KPI39599.1 - 8.6e-05 21.8 0.0 0.0014 17.8 0.0 2.2 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KPI39599.1 - 0.00025 21.1 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 KPI39599.1 - 0.0035 17.7 0.0 0.0098 16.3 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.21 KPI39599.1 - 0.0059 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ApbA PF02558.11 KPI39599.1 - 0.0083 15.5 0.0 0.023 14.1 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 KPI39599.1 - 0.0084 15.9 0.0 0.041 13.7 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NmrA PF05368.8 KPI39599.1 - 0.047 12.9 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Amidohydro_3 PF07969.6 KPI39600.1 - 4.5e-32 111.7 1.3 5.8e-32 111.3 0.9 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 KPI39600.1 - 6.6e-09 35.8 0.4 3.8e-08 33.3 0.2 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KPI39600.1 - 1.4e-08 35.1 0.8 0.00013 22.1 0.1 2.6 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KPI39600.1 - 3.9e-06 26.5 0.1 9.7e-06 25.3 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase Sugar_tr PF00083.19 KPI39601.1 - 4.6e-69 233.1 19.9 5.3e-69 232.9 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI39601.1 - 1.1e-21 77.0 44.4 3.1e-18 65.6 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4538 PF15061.1 KPI39601.1 - 2.4 7.5 4.7 2.9 7.2 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Iso_dh PF00180.15 KPI39603.1 - 3.2e-82 276.2 0.0 4e-82 275.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_S5_C PF03719.10 KPI39603.1 - 0.057 12.6 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain Copine PF07002.11 KPI39603.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 2 0 0 2 2 2 0 Copine Bestrophin PF01062.16 KPI39604.1 - 1e-44 152.7 0.6 3.2e-44 151.0 0.4 1.7 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel MIS13 PF08202.6 KPI39605.1 - 1.4e-54 185.2 2.3 2.3e-54 184.4 1.6 1.4 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Herpes_BLRF2 PF05812.7 KPI39605.1 - 0.0062 16.3 2.1 0.027 14.2 1.5 2.2 1 1 0 1 1 1 1 Herpesvirus BLRF2 protein FAM92 PF06730.6 KPI39605.1 - 0.03 13.6 0.1 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 FAM92 protein DivIC PF04977.10 KPI39605.1 - 0.059 12.8 1.4 0.16 11.4 0.9 1.6 1 0 0 1 1 1 0 Septum formation initiator Spore_GerAC PF05504.6 KPI39605.1 - 1 9.1 5.8 1.5 8.5 0.0 2.8 3 0 0 3 3 3 0 Spore germination B3/ GerAC like, C-terminal DUF904 PF06005.7 KPI39605.1 - 1.8 8.9 8.1 1 9.7 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF904) PS_Dcarbxylase PF02666.10 KPI39606.1 - 3.7e-53 179.8 0.0 5.6e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 KPI39606.1 - 2.8e-33 113.6 0.1 1.8e-15 56.5 0.0 2.6 2 0 0 2 2 2 2 C2 domain HMG_box PF00505.14 KPI39607.1 - 8.2e-17 61.2 0.6 1.7e-16 60.1 0.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KPI39607.1 - 1.1e-11 44.9 0.8 2e-11 44.0 0.6 1.5 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 KPI39607.1 - 1.7e-09 37.7 0.0 2.9e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KPI39607.1 - 1.4e-05 24.8 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) BTB PF00651.26 KPI39608.1 - 7.9e-12 45.1 0.1 2.5e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain CCDC155 PF14662.1 KPI39608.1 - 0.0039 16.7 0.7 0.0066 16.0 0.5 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 DivIC PF04977.10 KPI39608.1 - 0.013 14.9 0.6 0.095 12.2 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 KPI39608.1 - 0.024 14.4 0.5 0.051 13.3 0.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF2310 PF10071.4 KPI39610.1 - 0.12 11.2 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Hydrophobin_2 PF06766.6 KPI39611.1 - 5.2e-24 83.7 10.6 7.5e-24 83.2 7.3 1.2 1 0 0 1 1 1 1 Fungal hydrophobin MdcG PF10620.4 KPI39611.1 - 0.13 11.8 0.7 0.18 11.3 0.5 1.2 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG FAD_binding_4 PF01565.18 KPI39612.1 - 3e-29 101.2 0.0 4.8e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 KPI39612.1 - 3.3e-11 42.9 0.0 5.5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Fungal_trans PF04082.13 KPI39612.1 - 0.00025 19.9 0.0 0.00043 19.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_S26e PF01283.14 KPI39613.1 - 7e-51 171.2 8.2 8.3e-51 171.0 5.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Zn_ribbon_2 PF12674.2 KPI39613.1 - 0.064 13.6 0.2 8.4 6.8 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain DUF1918 PF08940.6 KPI39613.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Clathrin PF00637.15 KPI39614.1 - 4.4e-189 619.6 24.3 9.2e-33 112.8 1.4 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 KPI39614.1 - 1.3e-31 108.2 2.5 2.1e-31 107.6 0.4 2.5 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 KPI39614.1 - 4.3e-24 83.1 0.9 0.0014 18.7 0.0 7.5 7 0 0 7 7 7 6 Clathrin propeller repeat Ank_3 PF13606.1 KPI39614.1 - 0.085 13.1 0.0 1.2 9.6 0.0 3.1 2 0 0 2 2 2 0 Ankyrin repeat TPR_19 PF14559.1 KPI39614.1 - 0.82 10.0 7.8 2.9 8.3 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Raffinose_syn PF05691.7 KPI39617.1 - 1.8e-43 148.2 0.0 2.5e-40 137.7 0.1 2.9 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 ISN1 PF06437.6 KPI39620.1 - 1.1e-168 561.2 0.0 1.2e-168 561.0 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase TPP_enzyme_N PF02776.13 KPI39622.1 - 2.6e-43 147.4 0.1 1.8e-42 144.7 0.2 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KPI39622.1 - 8.1e-39 132.6 0.1 2.9e-38 130.8 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KPI39622.1 - 2.1e-17 63.1 0.0 4.2e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain B12-binding PF02310.14 KPI39622.1 - 0.073 12.9 0.0 0.28 11.0 0.0 1.9 1 0 0 1 1 1 0 B12 binding domain AA_permease PF00324.16 KPI39623.1 - 8.2e-140 466.3 38.6 1e-139 465.9 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI39623.1 - 2.4e-33 115.3 38.0 3.4e-33 114.8 26.4 1.1 1 0 0 1 1 1 1 Amino acid permease Myosin_HC-like PF07058.6 KPI39623.1 - 0.019 14.0 0.5 0.029 13.4 0.4 1.1 1 0 0 1 1 1 0 Myosin II heavy chain-like GHL12 PF14882.1 KPI39624.1 - 0.051 13.6 0.3 0.22 11.6 0.1 2.2 3 0 0 3 3 3 0 Hypothetical glycosyl hydrolase 12 PKK PF12474.3 KPI39624.1 - 5.2 6.7 13.3 6.8 6.4 6.2 2.4 2 0 0 2 2 2 0 Polo kinase kinase Abhydrolase_6 PF12697.2 KPI39625.1 - 1.1e-19 71.1 0.6 1.6e-19 70.6 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI39625.1 - 8.8e-13 48.2 0.0 3.3e-12 46.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI39625.1 - 4.8e-12 45.9 0.0 6.3e-10 39.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KPI39625.1 - 2.2e-05 24.2 0.0 4.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 KPI39625.1 - 0.023 13.9 0.2 1.9 7.7 0.0 2.9 2 1 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.6 KPI39625.1 - 0.1 12.3 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.20 KPI39625.1 - 0.1 12.2 0.1 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) Oleosin PF01277.12 KPI39625.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Oleosin NAD_binding_2 PF03446.10 KPI39626.1 - 1.6e-29 102.8 3.2 4.1e-29 101.5 2.2 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KPI39626.1 - 1.2e-22 80.2 0.0 2.1e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 KPI39626.1 - 1.3e-08 34.0 0.0 4.2e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 KPI39626.1 - 0.00027 21.3 0.0 0.00059 20.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 KPI39626.1 - 0.019 14.3 0.1 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TGF_beta_GS PF08515.7 KPI39626.1 - 0.2 11.0 1.3 0.45 9.9 0.9 1.6 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif PIP5K PF01504.13 KPI39627.1 - 7.8e-33 113.6 0.0 9.7e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Spc7_N PF15402.1 KPI39629.1 - 8.3e-245 815.0 63.9 8.3e-245 815.0 44.3 2.3 2 0 0 2 2 2 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 KPI39629.1 - 1.8e-86 289.8 9.8 1.8e-86 289.8 6.8 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein V_ATPase_I PF01496.14 KPI39629.1 - 7.8 4.2 3.6 15 3.2 2.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_M1 PF01433.15 KPI39630.1 - 8.7e-139 462.9 0.1 1.3e-138 462.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KPI39630.1 - 1e-87 294.4 0.1 1.7e-87 293.7 0.1 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KPI39630.1 - 6.5e-20 71.4 0.2 1.5e-19 70.3 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily SLAC1 PF03595.12 KPI39631.1 - 4.4e-68 229.3 48.8 5.6e-68 229.0 33.8 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel HET PF06985.6 KPI39631.1 - 8e-29 100.5 0.0 1.4e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribosomal_S5 PF00333.15 KPI39632.1 - 6.7e-29 99.4 2.6 2.7e-28 97.4 1.1 2.3 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KPI39632.1 - 3.1e-21 74.4 0.1 5.8e-21 73.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain SAP18 PF06487.7 KPI39632.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) Potassium_chann PF11404.3 KPI39632.1 - 0.55 10.0 2.6 1.2 8.9 1.8 1.5 1 0 0 1 1 1 0 Potassium voltage-gated channel RAM PF15320.1 KPI39632.1 - 6.8 7.0 9.1 13 6.1 6.3 1.3 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Methyltransf_11 PF08241.7 KPI39634.1 - 4.9e-15 55.7 0.0 9e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI39634.1 - 9.1e-13 48.7 0.0 1.9e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI39634.1 - 2.1e-10 40.3 0.0 4.3e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI39634.1 - 2.6e-10 40.6 0.0 5.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI39634.1 - 6.8e-09 35.6 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI39634.1 - 1e-07 31.3 0.0 1.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KPI39634.1 - 2.9e-07 30.7 0.0 9.1e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI39634.1 - 4.2e-07 29.9 0.0 5e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 KPI39634.1 - 9.9e-07 28.0 0.0 1.4e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.7 KPI39634.1 - 3e-05 23.0 0.0 4.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.9 KPI39634.1 - 4.7e-05 22.8 0.0 7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KPI39634.1 - 0.00038 19.5 0.0 0.00078 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.6 KPI39634.1 - 0.00075 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) FtsJ PF01728.14 KPI39634.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase TrkA_N PF02254.13 KPI39634.1 - 0.03 14.3 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain BTB PF00651.26 KPI39635.1 - 2.6e-08 33.8 0.0 0.00044 20.2 0.0 3.6 3 1 0 3 3 3 2 BTB/POZ domain XPC-binding PF09280.6 KPI39635.1 - 0.053 12.9 0.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 XPC-binding domain Peptidase_M3 PF01432.15 KPI39635.1 - 0.37 9.7 3.0 0.78 8.6 2.1 1.5 1 0 0 1 1 1 0 Peptidase family M3 IF-2B PF01008.12 KPI39636.1 - 2.1e-77 259.9 0.7 2.5e-77 259.6 0.5 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Spt5-NGN PF03439.8 KPI39637.1 - 2.7e-24 84.6 0.0 4.9e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 KPI39637.1 - 2.8e-15 56.7 11.8 2.8e-15 56.7 8.2 3.7 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.2 KPI39637.1 - 4e-15 56.3 52.2 2.3e-13 50.6 24.5 3.9 2 1 2 4 4 4 3 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.24 KPI39637.1 - 4.4e-07 29.3 11.8 0.004 16.8 0.2 5.2 5 0 0 5 5 5 4 KOW motif NusG PF02357.14 KPI39637.1 - 0.044 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Transcription termination factor nusG LSM PF01423.17 KPI39638.1 - 2.8e-19 68.4 0.0 3.2e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KPI39638.1 - 0.00023 21.0 0.1 0.00027 20.8 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Mannosyl_trans PF05007.8 KPI39639.1 - 3.7e-77 259.4 11.5 5.2e-77 258.9 8.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 KPI39639.1 - 2.4e-08 33.2 24.7 1.8e-07 30.3 16.6 2.4 1 1 1 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 KPI39639.1 - 4e-06 26.5 19.7 4e-06 26.5 13.6 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2029) 2OG-FeII_Oxy_2 PF13532.1 KPI39640.1 - 4.4e-18 65.7 0.0 5.4e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KPI39640.1 - 2.1e-05 24.7 0.0 3.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Epimerase PF01370.16 KPI39641.1 - 5.6e-16 58.6 0.0 1.1e-15 57.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI39641.1 - 3e-12 45.8 0.0 4.7e-12 45.1 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KPI39641.1 - 7.3e-09 35.8 0.1 1.5e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KPI39641.1 - 2e-08 33.5 0.0 8.2e-08 31.4 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KPI39641.1 - 0.00098 19.0 0.0 0.0047 16.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 KPI39641.1 - 0.0014 17.9 0.2 0.004 16.4 0.1 2.1 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 KPI39641.1 - 0.0029 16.5 0.0 0.0069 15.3 0.0 1.6 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 KPI39641.1 - 0.014 15.0 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 KR domain Glyco_hydro_16 PF00722.16 KPI39642.1 - 2.1e-21 76.0 0.2 4.7e-21 74.8 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.11 KPI39643.1 - 5.7e-16 58.1 37.4 3.1e-13 49.1 11.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI39643.1 - 1.8e-05 23.5 30.8 0.0057 15.2 21.4 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1705 PF08019.7 KPI39643.1 - 2.7 7.4 14.4 3.5 7.1 0.5 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1705) Med8 PF10232.4 KPI39644.1 - 6.3e-13 48.7 0.3 7.7e-13 48.4 0.2 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 IFT57 PF10498.4 KPI39644.1 - 0.032 12.9 3.2 0.088 11.5 1.5 1.9 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Nucleoplasmin PF03066.10 KPI39644.1 - 0.039 13.4 3.2 0.05 13.1 2.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 KPI39644.1 - 0.042 11.7 3.5 0.052 11.4 2.5 1.2 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 KPI39644.1 - 0.096 12.2 6.6 0.14 11.7 4.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF2457 PF10446.4 KPI39644.1 - 0.11 11.1 10.0 0.16 10.6 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 KPI39644.1 - 6 6.0 7.4 8.4 5.5 5.1 1.2 1 0 0 1 1 1 0 NOA36 protein DUF641 PF04859.7 KPI39645.1 - 0.0073 16.0 2.6 0.015 15.0 1.8 1.5 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) OmpH PF03938.9 KPI39645.1 - 0.23 11.3 4.8 0.3 11.0 3.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ABC_tran PF00005.22 KPI39646.1 - 4.3e-47 159.8 0.0 1.8e-25 89.8 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KPI39646.1 - 1.6e-15 57.8 0.1 0.0026 17.7 0.0 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 KPI39646.1 - 2e-13 50.0 0.1 0.00077 18.7 0.0 4.3 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KPI39646.1 - 4.6e-07 29.2 0.1 0.031 13.3 0.0 3.5 4 0 0 4 4 3 2 AAA ATPase domain AAA_29 PF13555.1 KPI39646.1 - 5e-07 29.1 0.3 0.0055 16.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KPI39646.1 - 7.4e-07 29.1 0.0 0.0064 16.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KPI39646.1 - 1.5e-06 27.5 0.1 0.0028 16.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KPI39646.1 - 1.6e-06 28.5 0.0 0.0037 17.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 KPI39646.1 - 5e-06 27.3 0.0 0.052 14.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KPI39646.1 - 5.4e-06 26.8 1.1 0.02 15.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 KPI39646.1 - 1.4e-05 24.7 1.0 1.6 8.0 0.1 4.3 4 1 0 4 4 4 2 AAA-like domain SbcCD_C PF13558.1 KPI39646.1 - 4.3e-05 23.3 0.0 0.62 10.0 0.0 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 KPI39646.1 - 4.8e-05 23.0 0.5 0.042 13.5 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_28 PF13521.1 KPI39646.1 - 5.7e-05 23.1 0.0 0.0065 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KPI39646.1 - 8e-05 22.7 0.0 0.23 11.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain Chromo PF00385.19 KPI39646.1 - 0.00025 20.6 0.3 0.0005 19.6 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF87 PF01935.12 KPI39646.1 - 0.00079 19.3 0.4 0.11 12.3 0.1 2.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 KPI39646.1 - 0.00085 19.0 0.0 0.97 9.1 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KPI39646.1 - 0.00091 19.3 0.1 0.54 10.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 KPI39646.1 - 0.0013 18.6 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KPI39646.1 - 0.0027 17.5 0.0 2.5 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 KPI39646.1 - 0.0034 16.8 0.1 0.92 8.9 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 KPI39646.1 - 0.0034 16.8 0.4 0.19 11.1 0.0 2.7 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 KPI39646.1 - 0.0034 17.6 0.1 0.61 10.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KPI39646.1 - 0.0042 17.2 0.1 0.5 10.5 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 KPI39646.1 - 0.0044 15.8 0.4 0.35 9.6 0.1 2.4 2 0 0 2 2 2 1 ArgK protein AAA_13 PF13166.1 KPI39646.1 - 0.0045 15.5 0.1 1.5 7.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KPI39646.1 - 0.0053 16.4 0.1 0.4 10.3 0.0 3.1 3 0 0 3 3 3 1 Archaeal ATPase Dynamin_N PF00350.18 KPI39646.1 - 0.0078 16.0 0.0 0.12 12.1 0.0 2.7 2 1 0 2 2 2 1 Dynamin family DUF815 PF05673.8 KPI39646.1 - 0.0081 15.1 0.2 0.64 8.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF3584 PF12128.3 KPI39646.1 - 0.0099 13.2 0.8 0.23 8.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) AAA_25 PF13481.1 KPI39646.1 - 0.023 14.0 0.0 8.7 5.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KPI39646.1 - 0.024 14.6 0.2 4.1 7.3 0.1 2.9 2 0 0 2 2 2 0 AAA ATPase domain ATP-synt_ab PF00006.20 KPI39646.1 - 0.028 13.9 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 KPI39646.1 - 0.038 12.8 0.1 1.4 7.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.13 KPI39646.1 - 0.064 12.2 0.1 4.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Septin Viral_helicase1 PF01443.13 KPI39646.1 - 0.067 12.6 0.1 4.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase HEAT_2 PF13646.1 KPI39646.1 - 0.077 13.2 0.2 2.6 8.3 0.0 3.1 1 1 1 2 2 2 0 HEAT repeats Adaptin_N PF01602.15 KPI39646.1 - 0.22 9.8 0.2 0.52 8.5 0.2 1.5 2 0 0 2 2 2 0 Adaptin N terminal region HMGL-like PF00682.14 KPI39648.1 - 2.9e-50 171.1 3.2 3.6e-28 98.8 0.0 2.4 1 1 1 2 2 2 2 HMGL-like zf-RING_2 PF13639.1 KPI39649.1 - 1.1e-09 38.0 4.7 2.3e-09 36.9 3.2 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 KPI39649.1 - 6.9e-05 22.7 4.9 0.00031 20.6 3.4 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 KPI39649.1 - 8.3e-05 22.5 2.0 0.00027 20.8 1.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KPI39649.1 - 0.0005 20.1 3.3 0.0015 18.6 2.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KPI39649.1 - 0.0014 18.3 2.4 0.0028 17.3 1.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain PHD PF00628.24 KPI39649.1 - 0.005 16.4 4.1 0.014 15.0 2.9 1.8 1 1 0 1 1 1 1 PHD-finger zf-C3HC4 PF00097.20 KPI39649.1 - 0.0076 15.8 1.1 0.03 13.9 0.8 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 KPI39649.1 - 0.059 13.4 2.0 0.12 12.4 1.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-Apc11 PF12861.2 KPI39649.1 - 0.061 13.1 3.5 0.062 13.1 0.4 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 KPI39649.1 - 0.065 12.9 3.8 0.61 9.8 1.6 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.1 KPI39649.1 - 0.1 12.3 3.4 0.27 10.9 2.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF329 PF03884.9 KPI39649.1 - 0.31 10.6 4.7 7.1 6.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-C3HC4_4 PF15227.1 KPI39649.1 - 0.56 10.1 4.7 0.55 10.1 0.9 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Cupin_2 PF07883.6 KPI39650.1 - 0.0086 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Fungal_trans PF04082.13 KPI39651.1 - 4.9e-08 32.1 0.1 9.5e-08 31.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1772 PF08592.6 KPI39652.1 - 6.9e-11 42.0 0.0 1.1e-10 41.4 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Methyltransf_23 PF13489.1 KPI39653.1 - 2.4e-17 63.1 0.0 3.4e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI39653.1 - 3.9e-14 52.4 0.0 1.7e-13 50.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI39653.1 - 4.5e-13 49.5 0.0 1.3e-11 44.7 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI39653.1 - 3.9e-12 46.5 0.1 7e-11 42.4 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI39653.1 - 1.6e-10 41.5 0.1 7.6e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI39653.1 - 5e-08 33.2 0.0 3.5e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 KPI39653.1 - 5.3e-07 29.3 0.0 9.6e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 KPI39653.1 - 2.9e-06 26.5 0.0 5.7e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 KPI39653.1 - 7.5e-06 26.0 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KPI39653.1 - 2.5e-05 24.2 0.0 4.1e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KPI39653.1 - 0.00012 21.5 0.1 0.0016 17.8 0.0 2.1 1 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.1 KPI39653.1 - 0.00015 21.4 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.12 KPI39653.1 - 0.00076 18.4 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin CMAS PF02353.15 KPI39653.1 - 0.0015 17.6 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase GCD14 PF08704.5 KPI39653.1 - 0.003 17.0 0.0 0.0053 16.2 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_9 PF08003.6 KPI39653.1 - 0.035 12.7 0.0 0.059 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RrnaAD PF00398.15 KPI39653.1 - 0.04 12.9 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PC-Esterase PF13839.1 KPI39653.1 - 0.041 13.6 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PrmA PF06325.8 KPI39653.1 - 0.051 12.6 0.1 0.15 11.1 0.1 1.7 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 KPI39653.1 - 0.14 11.5 0.1 0.41 9.9 0.0 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Citrate_synt PF00285.16 KPI39654.1 - 1.4e-65 221.3 0.0 1.4e-32 112.8 0.0 2.5 3 0 0 3 3 3 2 Citrate synthase COesterase PF00135.23 KPI39656.1 - 2.2e-62 211.4 0.0 2.9e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI39656.1 - 3.9e-10 39.6 0.1 9.9e-10 38.3 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI39656.1 - 0.00075 19.2 0.1 0.0014 18.4 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KPI39656.1 - 0.0027 17.1 0.0 0.0076 15.7 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Abhydrolase_6 PF12697.2 KPI39656.1 - 0.0045 16.8 0.6 0.0099 15.7 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI39656.1 - 0.12 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2424 PF10340.4 KPI39656.1 - 0.13 10.9 0.0 0.33 9.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Isochorismatase PF00857.15 KPI39657.1 - 2.7e-45 154.3 0.0 3.1e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Alpha-amylase PF00128.19 KPI39658.1 - 5.6e-84 282.2 0.0 7.9e-84 281.7 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.3 KPI39658.1 - 0.0011 19.0 0.1 0.0024 17.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) hDGE_amylase PF14701.1 KPI39658.1 - 0.056 12.3 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Ank PF00023.25 KPI39659.1 - 1.5e-15 56.1 0.9 3e-10 39.3 0.3 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KPI39659.1 - 3.2e-14 53.0 0.0 5.2e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KPI39659.1 - 1.4e-11 44.5 0.6 1e-06 29.0 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI39659.1 - 6.7e-10 38.2 0.2 2.2e-07 30.4 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KPI39659.1 - 8.5e-09 35.3 0.2 9.6e-08 32.0 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) FAD_binding_3 PF01494.14 KPI39660.1 - 4.4e-42 144.4 0.0 7.6e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI39660.1 - 5.4e-05 22.2 0.2 0.098 11.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI39660.1 - 7.6e-05 22.6 0.4 0.00021 21.2 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI39660.1 - 0.00014 21.7 0.2 0.00037 20.4 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI39660.1 - 0.00021 19.8 1.3 0.0012 17.3 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 KPI39660.1 - 0.00066 18.7 0.2 0.023 13.6 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KPI39660.1 - 0.0043 15.9 0.4 0.048 12.4 0.1 2.0 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KPI39660.1 - 0.0044 17.3 0.2 3 8.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI39660.1 - 0.017 14.1 0.2 0.035 13.2 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KPI39660.1 - 0.044 13.8 0.2 0.067 13.2 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI39660.1 - 0.08 11.7 0.1 0.11 11.3 0.1 1.3 1 1 0 1 1 1 0 Glucose inhibited division protein A SUR7 PF06687.7 KPI39661.1 - 2.3e-31 109.0 8.3 2.8e-31 108.7 5.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family CDC45 PF02724.9 KPI39662.1 - 2.6 5.9 7.5 3.9 5.4 5.2 1.2 1 0 0 1 1 1 0 CDC45-like protein GDPD PF03009.12 KPI39663.1 - 7.6e-16 58.3 0.0 1e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family LIP PF03583.9 KPI39664.1 - 3.7e-74 249.5 0.1 5e-74 249.0 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 KPI39664.1 - 0.00038 20.2 0.0 0.00081 19.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KPI39664.1 - 0.073 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Cutinase FAD_binding_3 PF01494.14 KPI39665.1 - 7e-21 74.6 0.0 3.9e-12 45.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KPI39665.1 - 8.4e-08 32.1 0.3 2e-07 30.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI39665.1 - 7.7e-05 21.7 1.1 0.00033 19.6 0.4 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI39665.1 - 9.2e-05 21.4 1.6 0.00042 19.2 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KPI39665.1 - 0.00098 19.0 0.3 0.0021 17.9 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KPI39665.1 - 0.0025 17.6 0.2 0.0058 16.4 0.1 1.6 1 0 0 1 1 1 1 ThiF family SE PF08491.5 KPI39665.1 - 0.0074 15.1 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.22 KPI39665.1 - 0.009 16.3 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI39665.1 - 0.025 13.6 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KPI39665.1 - 0.039 14.0 0.2 0.1 12.6 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KPI39665.1 - 0.039 12.5 0.1 0.056 12.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 KPI39665.1 - 0.054 12.3 0.3 0.077 11.8 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 KPI39665.1 - 0.058 12.7 0.2 0.058 12.7 0.1 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KPI39665.1 - 0.13 12.0 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 KPI39665.1 - 0.13 10.7 0.1 0.3 9.5 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein zf-C2H2_4 PF13894.1 KPI39667.1 - 1.2 9.6 8.2 12 6.4 0.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger mRNA_triPase PF02940.10 KPI39668.1 - 7.4e-45 153.3 0.0 1e-44 152.8 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain EamA PF00892.15 KPI39669.1 - 1e-14 54.6 25.3 8.2e-08 32.3 2.1 2.6 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KPI39669.1 - 2.6e-06 27.6 22.7 4.2e-06 26.9 2.4 3.0 2 2 0 2 2 2 2 Multidrug resistance efflux transporter UAA PF08449.6 KPI39669.1 - 7.4e-05 21.8 2.9 0.00013 20.9 2.0 1.4 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 KPI39669.1 - 0.0026 16.8 0.1 0.0061 15.6 0.0 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 KPI39669.1 - 0.008 15.8 6.6 0.008 15.8 4.5 2.9 3 1 0 3 3 3 2 Triose-phosphate Transporter family F-box-like PF12937.2 KPI39670.1 - 2.2e-06 27.2 0.1 2.3e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 KPI39670.1 - 0.045 13.8 0.9 0.74 10.0 0.4 3.1 3 0 0 3 3 3 0 Leucine Rich repeat PC_rep PF01851.17 KPI39671.1 - 1.2e-35 119.7 16.8 2.3e-09 36.9 0.0 9.8 10 0 0 10 10 10 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KPI39671.1 - 2.1e-14 53.5 0.3 3.4e-12 46.4 0.0 4.3 3 2 2 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 KPI39671.1 - 2.7e-10 40.4 1.5 4.3e-06 27.0 0.0 5.2 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.17 KPI39671.1 - 3.5e-07 29.7 1.0 0.44 10.7 0.0 5.4 6 0 0 6 6 6 3 HEAT repeat HEAT_PBS PF03130.11 KPI39671.1 - 0.018 15.4 0.9 0.84 10.2 0.0 3.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat RICTOR_V PF14668.1 KPI39671.1 - 0.23 11.3 0.8 12 5.9 0.0 3.5 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 DEP PF00610.16 KPI39672.1 - 0.016 14.9 0.0 0.073 12.8 0.0 1.9 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Mpv17_PMP22 PF04117.7 KPI39673.1 - 1.4e-26 91.8 0.4 2.7e-26 90.9 0.3 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family 3Beta_HSD PF01073.14 KPI39673.1 - 0.066 11.8 0.0 6.8 5.2 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KPI39674.1 - 5.6e-27 94.6 3.5 7.6e-27 94.2 2.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI39674.1 - 7.1e-24 84.9 0.1 8.8e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI39674.1 - 2.4e-15 56.6 2.2 3.4e-15 56.1 1.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI39674.1 - 0.032 13.6 0.1 0.048 13.0 0.1 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FHA PF00498.21 KPI39675.1 - 2.3e-06 27.6 0.0 4.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 KPI39675.1 - 0.072 13.2 0.1 1.2 9.3 0.0 2.8 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DUF3543 PF12063.3 KPI39676.1 - 5.4e-84 281.1 0.2 8e-84 280.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 KPI39676.1 - 6e-59 199.3 0.0 1.4e-58 198.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI39676.1 - 2.4e-42 144.8 0.0 4.2e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI39676.1 - 0.0012 17.8 0.0 0.028 13.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KPI39676.1 - 0.014 15.1 0.1 0.048 13.3 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family DEAD PF00270.24 KPI39677.1 - 6.1e-47 159.2 0.0 3.6e-45 153.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI39677.1 - 3.9e-28 97.1 0.1 7.9e-28 96.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Fungal_trans_2 PF11951.3 KPI39677.1 - 0.0013 17.4 0.2 0.0022 16.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ResIII PF04851.10 KPI39677.1 - 0.012 15.3 0.0 0.028 14.2 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 KPI39677.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AMP-binding PF00501.23 KPI39678.1 - 1.2e-57 195.2 0.0 1.7e-57 194.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ATP12 PF07542.6 KPI39679.1 - 0.043 13.7 0.7 0.071 13.0 0.5 1.2 1 0 0 1 1 1 0 ATP12 chaperone protein Rad60-SLD PF11976.3 KPI39680.1 - 1e-14 53.9 0.0 5.6e-14 51.5 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KPI39680.1 - 0.00024 20.4 0.0 0.00047 19.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Fungal_trans PF04082.13 KPI39681.1 - 2.6e-08 33.0 0.0 3.5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AKNA PF12443.3 KPI39682.1 - 0.07 13.1 0.2 0.085 12.8 0.1 1.0 1 0 0 1 1 1 0 AT-hook-containing transcription factor ArfGap PF01412.13 KPI39683.1 - 7.3e-05 22.5 0.4 0.00021 21.0 0.3 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-ribbon_3 PF13248.1 KPI39683.1 - 0.017 14.3 1.3 0.032 13.4 0.9 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Cyt-b5 PF00173.23 KPI39684.1 - 9.1e-15 54.2 0.0 1.5e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Rib_recp_KP_reg PF05104.7 KPI39684.1 - 3.6 8.0 7.9 12 6.4 5.5 1.8 1 1 0 1 1 1 0 Ribosome receptor lysine/proline rich region PFK PF00365.15 KPI39685.1 - 9.5e-146 484.1 0.2 1.1e-101 339.4 0.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase XPA_N PF01286.13 KPI39685.1 - 0.092 12.4 0.4 0.26 10.9 0.3 1.7 1 0 0 1 1 1 0 XPA protein N-terminal UVR PF02151.14 KPI39685.1 - 0.11 12.0 0.1 0.24 10.9 0.1 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif Epimerase PF01370.16 KPI39686.1 - 0.00042 19.8 0.0 0.00072 19.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 KPI39687.1 - 9.3e-41 139.6 26.9 9.3e-41 139.6 18.6 2.3 1 1 2 3 3 3 1 Major Facilitator Superfamily 2TM PF13239.1 KPI39687.1 - 0.057 13.4 14.3 1.3 9.0 0.5 4.5 4 0 0 4 4 4 0 2TM domain Abhydrolase_6 PF12697.2 KPI39688.1 - 6.7e-12 45.7 0.0 9.5e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI39688.1 - 2.3e-07 30.6 0.0 2.8e-07 30.3 0.0 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KPI39688.1 - 0.0078 15.8 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.7 KPI39688.1 - 0.009 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_8 PF06259.7 KPI39688.1 - 0.018 14.5 0.0 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase LCAT PF02450.10 KPI39688.1 - 0.036 13.0 0.0 0.06 12.3 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase zf-primase PF09329.6 KPI39690.1 - 0.0097 15.4 0.6 0.39 10.3 0.1 2.5 2 0 0 2 2 2 2 Primase zinc finger zf-H2C2_2 PF13465.1 KPI39691.1 - 8.6e-05 22.6 0.1 8.6e-05 22.6 0.1 4.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KPI39691.1 - 0.00023 21.2 23.6 0.0037 17.4 0.4 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI39691.1 - 0.0016 18.6 25.1 0.0085 16.3 0.6 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type PyrI_C PF02748.10 KPI39691.1 - 0.0086 15.4 0.1 0.062 12.7 0.0 2.1 2 0 0 2 2 2 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain Ribosomal_L44 PF00935.14 KPI39691.1 - 0.44 10.5 0.1 0.44 10.5 0.0 2.4 3 0 0 3 3 3 0 Ribosomal protein L44 zf-C2H2_2 PF12756.2 KPI39691.1 - 0.73 9.9 4.6 7.1 6.7 0.2 2.5 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 KPI39691.1 - 2.9 8.3 12.0 1 9.7 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-BED PF02892.10 KPI39691.1 - 4.1 7.2 11.9 0.7 9.6 0.1 3.4 3 0 0 3 3 3 0 BED zinc finger CBS PF00571.23 KPI39692.1 - 1.1e-36 124.3 1.9 2.5e-11 43.1 0.0 4.2 4 0 0 4 4 4 4 CBS domain DUF2252 PF10009.4 KPI39692.1 - 0.11 11.3 1.1 0.25 10.1 0.3 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF3235 PF11574.3 KPI39692.1 - 0.12 12.6 0.0 0.45 10.7 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3235) APG6 PF04111.7 KPI39693.1 - 0.0073 15.3 0.8 0.0087 15.1 0.5 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 Baculo_PEP_C PF04513.7 KPI39693.1 - 0.016 15.0 0.3 0.02 14.6 0.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peripla_BP_2 PF01497.13 KPI39693.1 - 0.022 13.8 0.3 0.025 13.7 0.2 1.1 1 0 0 1 1 1 0 Periplasmic binding protein RmuC PF02646.11 KPI39693.1 - 0.029 13.2 1.3 0.031 13.1 0.9 1.0 1 0 0 1 1 1 0 RmuC family Exonuc_VII_S PF02609.11 KPI39693.1 - 0.034 13.9 0.7 0.052 13.3 0.5 1.3 1 0 0 1 1 1 0 Exonuclease VII small subunit UPF0184 PF03670.8 KPI39693.1 - 0.075 13.2 0.9 0.15 12.2 0.6 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) DUF3422 PF11902.3 KPI39693.1 - 0.09 11.6 1.1 0.1 11.4 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) zf-ZPR1 PF03367.8 KPI39693.1 - 0.17 11.0 0.3 0.24 10.5 0.2 1.3 1 1 0 1 1 1 0 ZPR1 zinc-finger domain MbeB_N PF04837.7 KPI39693.1 - 0.41 10.7 2.4 0.82 9.8 1.6 1.5 1 1 0 1 1 1 0 MbeB-like, N-term conserved region DUF2514 PF10721.4 KPI39693.1 - 0.97 9.1 5.2 1.1 8.9 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Aminotran_1_2 PF00155.16 KPI39694.1 - 1.4e-42 145.9 0.0 1.8e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KPI39694.1 - 1.3e-07 30.2 0.0 1.9e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KPI39694.1 - 0.0025 16.9 0.2 0.0042 16.1 0.1 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1205 PF06722.7 KPI39694.1 - 0.065 13.4 0.1 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) OKR_DC_1 PF01276.15 KPI39694.1 - 0.19 10.1 0.0 0.28 9.6 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain ICL PF00463.16 KPI39695.1 - 3.4e-187 622.8 1.4 3.9e-187 622.6 1.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KPI39695.1 - 3.9e-09 36.0 0.0 1.8e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Fer4_18 PF13746.1 KPI39696.1 - 0.42 11.0 0.8 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain p450 PF00067.17 KPI39697.1 - 6.5e-65 219.4 0.0 8.1e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PB1 PF00564.19 KPI39698.1 - 4.2e-10 39.1 0.0 7.6e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 PB1 domain Spore_YhcN_YlaJ PF09580.5 KPI39698.1 - 0.12 12.4 0.4 5 7.1 0.1 2.5 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) GMC_oxred_N PF00732.14 KPI39699.1 - 1.8e-64 217.7 0.0 2.3e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI39699.1 - 1.2e-35 122.9 0.0 2e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KPI39699.1 - 1.8e-05 23.8 1.4 0.00065 18.7 0.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KPI39699.1 - 2.2e-05 24.6 0.2 0.13 12.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI39699.1 - 0.00015 20.7 1.2 0.0098 14.7 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KPI39699.1 - 0.00056 19.8 0.4 0.002 18.0 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KPI39699.1 - 0.0029 16.5 0.2 0.0043 16.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KPI39699.1 - 0.043 13.7 0.1 0.35 10.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI39699.1 - 0.063 12.3 0.1 0.17 10.9 0.1 1.7 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KPI39699.1 - 0.082 11.3 0.1 0.14 10.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 KPI39699.1 - 0.1 13.0 0.4 2.4 8.6 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.27 KPI39700.1 - 0.0017 18.1 0.7 0.22 11.4 0.0 3.2 3 1 0 3 3 3 2 WD domain, G-beta repeat HSP33 PF01430.14 KPI39700.1 - 0.13 11.3 0.1 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Hsp33 protein Fungal_trans PF04082.13 KPI39701.1 - 2.5e-05 23.2 0.1 7.3e-05 21.7 0.0 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain SET PF00856.23 KPI39702.1 - 9.6e-20 71.5 1.9 8.7e-19 68.3 0.0 2.8 2 2 0 2 2 2 1 SET domain Daxx PF03344.10 KPI39702.1 - 0.58 8.5 10.1 0.7 8.2 7.0 1.2 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 KPI39702.1 - 6 7.1 11.4 13 6.0 7.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-CSL PF05207.8 KPI39703.1 - 1.5e-14 53.2 0.2 2.1e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 KPI39703.1 - 1.1e-13 50.6 0.3 1.7e-13 50.0 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain HRDC PF00570.18 KPI39703.1 - 0.0083 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 HRDC domain DUF3665 PF12427.3 KPI39703.1 - 0.099 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase GLTP PF08718.6 KPI39703.1 - 0.22 11.5 0.6 0.69 9.9 0.1 1.9 1 1 1 2 2 2 0 Glycolipid transfer protein (GLTP) DUF3336 PF11815.3 KPI39704.1 - 1.7e-26 92.4 0.9 3.3e-26 91.5 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KPI39704.1 - 5e-11 42.9 0.0 1.4e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase Ribonuc_L-PSP PF01042.16 KPI39705.1 - 1.8e-08 34.1 0.1 0.0005 19.8 0.0 3.8 3 1 0 3 3 3 2 Endoribonuclease L-PSP ATP_bind_4 PF01902.12 KPI39705.1 - 2.7e-08 33.4 0.0 4.1e-07 29.5 0.0 2.2 1 1 0 1 1 1 1 ATP-binding region AhpC-TSA_2 PF13911.1 KPI39706.1 - 1.2e-16 60.5 0.0 2.5e-16 59.6 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KPI39706.1 - 2.1e-06 27.4 0.0 2.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KPI39706.1 - 3.3e-05 23.4 0.0 4.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.7 KPI39706.1 - 0.021 14.2 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Kelch_3 PF13415.1 KPI39707.1 - 1.1e-19 70.0 7.0 3e-10 39.9 0.0 5.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.1 KPI39707.1 - 6.1e-19 67.5 4.3 2.6e-11 43.1 0.0 5.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KPI39707.1 - 6.1e-14 51.5 1.3 2.3e-05 24.3 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 KPI39707.1 - 2.9e-12 45.9 0.0 0.0015 18.0 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.1 KPI39707.1 - 7.3e-11 41.7 3.1 0.0012 18.7 0.0 4.3 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 KPI39707.1 - 1.7e-09 37.0 0.0 6.1e-05 22.6 0.0 4.0 3 0 0 3 3 3 2 Kelch motif BTB PF00651.26 KPI39707.1 - 0.00026 20.9 0.0 0.016 15.2 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain HRXXH PF13933.1 KPI39708.1 - 3.9e-100 334.3 0.1 5.3e-100 333.9 0.1 1.1 1 0 0 1 1 1 1 Putative peptidase family Big_4 PF07532.6 KPI39708.1 - 0.00096 18.6 0.5 0.0019 17.6 0.3 1.4 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 4) HCV_NS5a_1a PF08300.8 KPI39708.1 - 0.1 12.5 0.4 0.27 11.1 0.3 1.7 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a zinc finger domain p450 PF00067.17 KPI39709.1 - 1e-67 228.6 0.0 1.3e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2235 PF09994.4 KPI39710.1 - 6.2e-67 225.8 0.0 8.7e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KPI39710.1 - 0.028 14.1 0.0 0.047 13.4 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family PY_rept_46 PF09689.5 KPI39710.1 - 0.13 12.5 0.5 0.27 11.5 0.4 1.5 1 0 0 1 1 1 0 Plasmodium yoelii repeat (PY_rept_46) SAM_2 PF07647.12 KPI39711.1 - 8.3e-09 35.1 0.0 1.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KPI39711.1 - 4.1e-08 33.2 0.1 8.6e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 KPI39711.1 - 0.00019 21.6 0.1 0.00045 20.3 0.0 1.7 1 0 0 1 1 1 1 PH domain ArsA_ATPase PF02374.10 KPI39711.1 - 0.18 10.8 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase HMA PF00403.21 KPI39712.1 - 0.00024 21.1 0.2 0.00051 20.1 0.1 1.6 1 1 0 1 1 1 1 Heavy-metal-associated domain ACT_6 PF13740.1 KPI39712.1 - 0.053 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 ACT domain R3H PF01424.17 KPI39714.1 - 5.1e-14 51.7 0.1 5.1e-14 51.7 0.0 1.7 2 0 0 2 2 2 1 R3H domain NAD_binding_2 PF03446.10 KPI39715.1 - 3e-34 118.2 0.0 4e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KPI39715.1 - 1.5e-24 86.3 0.0 2.5e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 KPI39715.1 - 0.0043 15.8 0.0 0.0064 15.2 0.0 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 KPI39715.1 - 0.017 15.5 0.0 0.048 14.0 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KPI39715.1 - 0.035 13.8 0.0 0.082 12.6 0.0 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 KPI39715.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cut8_M PF14483.1 KPI39715.1 - 1 9.1 4.2 1.8 8.4 0.2 2.3 2 0 0 2 2 2 0 Cut8 dimerisation domain Oxidored_FMN PF00724.15 KPI39716.1 - 6.5e-53 179.8 0.0 9.9e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RPOL_N PF14700.1 KPI39716.1 - 0.042 13.1 0.0 5.9 6.0 0.0 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal Dus PF01207.12 KPI39716.1 - 0.094 11.5 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 KPI39717.1 - 0.00032 20.2 1.9 0.00061 19.4 1.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-MYND PF01753.13 KPI39717.1 - 0.0092 15.8 1.0 0.017 14.9 0.7 1.4 1 0 0 1 1 1 1 MYND finger ParBc PF02195.13 KPI39717.1 - 0.078 13.0 0.1 14 5.8 0.0 2.5 2 0 0 2 2 2 0 ParB-like nuclease domain IF4E PF01652.13 KPI39718.1 - 1.9e-59 199.8 0.9 2.4e-59 199.5 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.20 KPI39719.1 - 3.6e-23 82.0 0.0 2.2e-21 76.1 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain RPEL PF02755.10 KPI39720.1 - 1.7e-24 84.4 21.2 1.9e-09 36.5 0.5 3.7 4 0 0 4 4 4 3 RPEL repeat CP12 PF02672.10 KPI39720.1 - 0.0038 17.6 0.8 3.5 8.1 0.1 2.9 3 0 0 3 3 3 2 CP12 domain MEA1 PF06910.6 KPI39720.1 - 0.052 13.2 0.2 0.11 12.1 0.1 1.5 1 1 0 1 1 1 0 Male enhanced antigen 1 (MEA1) CRC_subunit PF08624.5 KPI39720.1 - 0.15 11.9 0.4 1.1 9.1 0.0 2.2 1 1 2 3 3 3 0 Chromatin remodelling complex Rsc7/Swp82 subunit Fungal_trans_2 PF11951.3 KPI39721.1 - 4.5e-05 22.2 0.6 8.1e-05 21.3 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Amidohydro_2 PF04909.9 KPI39722.1 - 1e-11 44.9 0.3 1.5e-11 44.4 0.2 1.3 1 0 0 1 1 1 1 Amidohydrolase AIG2_2 PF13772.1 KPI39723.1 - 3.2e-06 27.1 0.3 1.1e-05 25.4 0.2 1.9 1 1 0 1 1 1 1 AIG2-like family FMO-like PF00743.14 KPI39724.1 - 2.2e-29 102.0 0.0 5.2e-19 67.8 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KPI39724.1 - 1.8e-21 77.1 0.0 1.1e-14 55.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI39724.1 - 2e-11 43.4 2.0 9.9e-07 27.9 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KPI39724.1 - 7.7e-10 38.2 0.1 1.3e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KPI39724.1 - 2.6e-09 37.2 0.0 3.9e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI39724.1 - 3e-08 33.5 2.9 0.0018 18.0 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KPI39724.1 - 1e-06 28.6 0.1 6.8e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KPI39724.1 - 6.6e-06 25.4 0.0 0.011 14.8 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KPI39724.1 - 0.00013 22.3 2.6 0.049 14.0 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KPI39724.1 - 0.00037 20.6 0.0 0.031 14.3 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DUF1264 PF06884.6 KPI39724.1 - 0.0015 18.0 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) FAD_binding_3 PF01494.14 KPI39724.1 - 0.0056 15.7 0.2 0.013 14.5 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KPI39724.1 - 0.011 14.8 0.1 0.047 12.7 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KPI39724.1 - 0.051 12.4 0.1 0.13 11.0 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 KPI39724.1 - 0.06 12.4 0.2 0.28 10.2 0.0 2.1 3 0 0 3 3 3 0 Thi4 family HI0933_like PF03486.9 KPI39724.1 - 0.06 11.8 0.6 0.83 8.0 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein ThiF PF00899.16 KPI39724.1 - 0.063 13.1 1.3 1.7 8.4 0.1 2.8 3 0 0 3 3 3 0 ThiF family NAD_binding_7 PF13241.1 KPI39724.1 - 0.11 12.7 0.0 23 5.2 0.0 2.7 3 0 0 3 3 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 KPI39724.1 - 0.14 11.8 0.4 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KPI39724.1 - 0.17 10.7 0.1 0.17 10.7 0.1 2.0 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.7 KPI39724.1 - 0.26 10.1 2.2 2.9 6.7 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein PIN_4 PF13638.1 KPI39725.1 - 0.045 13.8 0.1 0.23 11.5 0.1 2.0 2 0 0 2 2 2 0 PIN domain TFIIA PF03153.8 KPI39726.1 - 0.96 9.2 4.5 1.3 8.8 3.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NAD_binding_3 PF03447.11 KPI39728.1 - 1.4e-06 28.6 0.1 4.9e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 KPI39728.1 - 0.00015 22.2 0.1 0.00043 20.7 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 KPI39728.1 - 0.0033 17.3 0.1 0.039 13.8 0.0 2.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus SAF PF08666.7 KPI39728.1 - 0.0082 16.5 0.3 0.02 15.2 0.0 1.8 2 0 0 2 2 2 1 SAF domain MPC PF03650.8 KPI39729.1 - 6.7e-35 119.6 0.1 8.7e-35 119.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) CsbD PF05532.7 KPI39729.1 - 0.17 11.5 3.2 0.46 10.1 0.2 2.3 1 1 1 2 2 2 0 CsbD-like Adaptin_N PF01602.15 KPI39730.1 - 5.9e-123 410.9 5.8 7.2e-123 410.6 4.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KPI39730.1 - 6.9e-31 106.5 0.0 1.7e-30 105.2 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 KPI39730.1 - 8.3e-16 58.3 0.1 1.6e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KPI39730.1 - 0.00064 19.9 0.9 0.28 11.5 0.0 4.2 3 2 2 5 5 5 2 HEAT repeats p450 PF00067.17 KPI39733.1 - 2.6e-56 191.0 0.0 3.7e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SQS_PSY PF00494.14 KPI39734.1 - 2.1e-37 128.9 0.0 2.8e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Peroxin-22 PF12827.2 KPI39734.1 - 0.071 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family zf-DHHC PF01529.15 KPI39734.1 - 0.14 11.5 4.0 4.9 6.5 2.8 2.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase LSM PF01423.17 KPI39735.1 - 3.4e-09 36.1 0.0 4.2e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KPI39735.1 - 0.00028 20.7 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain MFS_1 PF07690.11 KPI39736.1 - 2.2e-28 99.0 44.7 1.8e-19 69.6 8.7 3.4 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KPI39736.1 - 1e-09 37.1 19.5 3.7e-08 32.0 6.2 2.2 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KPI39736.1 - 2e-08 33.2 7.1 2e-08 33.2 4.9 3.2 3 1 0 4 4 4 1 Sugar (and other) transporter Memo PF01875.12 KPI39737.1 - 3.4e-65 219.6 0.0 4e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein MFS_1 PF07690.11 KPI39738.1 - 6.8e-23 80.9 26.4 9.2e-23 80.5 18.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KPI39738.1 - 3.3e-07 28.9 0.7 6.2e-07 28.0 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Abhydrolase_5 PF12695.2 KPI39739.1 - 4.2e-10 39.5 0.0 7.1e-10 38.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI39739.1 - 9.5e-09 35.4 0.6 2.6e-08 34.0 0.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI39739.1 - 0.013 15.0 0.2 0.042 13.4 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KPI39739.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KPI39739.1 - 0.03 14.1 0.5 0.11 12.3 0.1 2.1 2 1 0 2 2 2 0 Putative lysophospholipase TPR_MLP1_2 PF07926.7 KPI39740.1 - 0.0029 17.3 0.2 0.0029 17.3 0.2 7.5 3 2 2 5 5 5 2 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 KPI39740.1 - 0.0062 16.3 6.5 0.0062 16.3 4.5 7.2 5 3 1 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Diphthamide_syn PF01866.12 KPI39741.1 - 1.7e-49 168.7 0.0 3.5e-49 167.6 0.0 1.5 1 1 0 1 1 1 1 Putative diphthamide synthesis protein AAA PF00004.24 KPI39742.1 - 4.2e-14 52.8 0.0 1e-13 51.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KPI39742.1 - 3.2e-05 24.7 0.1 0.00013 22.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KPI39742.1 - 7.9e-05 22.5 0.0 0.00047 20.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KPI39742.1 - 8.3e-05 22.6 0.2 0.00022 21.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KPI39742.1 - 0.00018 21.6 0.9 0.034 14.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KPI39742.1 - 0.0028 17.3 0.3 0.0068 16.1 0.1 1.9 2 1 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 KPI39742.1 - 0.003 17.4 0.0 0.007 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KPI39742.1 - 0.0031 16.9 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.20 KPI39742.1 - 0.0059 16.1 0.1 0.024 14.1 0.0 1.9 2 1 1 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 KPI39742.1 - 0.0084 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 KPI39742.1 - 0.0099 15.6 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zot PF05707.7 KPI39742.1 - 0.025 14.0 1.4 0.25 10.8 0.2 2.5 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_11 PF13086.1 KPI39742.1 - 0.052 13.1 0.1 0.074 12.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KPI39742.1 - 0.057 13.6 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 RNA helicase RuvB_N PF05496.7 KPI39742.1 - 0.061 12.3 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 KPI39742.1 - 0.092 12.3 0.7 0.52 9.8 0.0 2.2 2 1 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KPI39742.1 - 0.096 12.9 0.1 0.19 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KPI39742.1 - 0.15 12.3 0.4 0.5 10.6 0.3 2.1 1 1 0 1 1 1 0 ABC transporter ArgK PF03308.11 KPI39742.1 - 0.17 10.6 1.3 0.74 8.5 0.0 2.1 2 0 0 2 2 2 0 ArgK protein WD40 PF00400.27 KPI39743.1 - 2.2e-22 78.0 11.5 3.5e-08 33.0 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Rax2 PF12768.2 KPI39743.1 - 0.00085 18.6 0.3 0.0049 16.1 0.0 2.1 3 0 0 3 3 3 1 Cortical protein marker for cell polarity IKI3 PF04762.7 KPI39743.1 - 0.12 10.1 0.0 2.3 5.9 0.0 2.6 3 0 0 3 3 3 0 IKI3 family Glyco_hydro_17 PF00332.13 KPI39745.1 - 0.0062 15.6 2.1 0.0062 15.6 1.5 1.9 2 1 0 2 2 2 1 Glycosyl hydrolases family 17 Fungal_trans PF04082.13 KPI39746.1 - 1.3e-09 37.3 2.4 2.9e-09 36.1 0.3 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain PITH PF06201.8 KPI39747.1 - 1.4e-43 148.2 0.9 2e-43 147.7 0.6 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 KPI39747.1 - 1.6e-27 95.1 0.0 3.4e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KPI39747.1 - 2.5e-07 30.7 0.0 0.0001 22.3 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KPI39747.1 - 2.2e-06 27.8 0.0 7.4e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KPI39747.1 - 0.0001 21.8 0.1 0.12 11.8 0.0 2.4 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 KPI39747.1 - 0.00079 19.1 0.0 0.14 11.8 0.0 2.3 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 KPI39747.1 - 0.013 15.4 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.1 KPI39747.1 - 0.034 13.7 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin AAL_decarboxy PF03306.8 KPI39748.1 - 1.8e-71 239.7 1.6 2e-71 239.5 1.1 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase MDM31_MDM32 PF08118.6 KPI39749.1 - 8.3e-191 634.8 0.0 9.7e-191 634.5 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins DUF2413 PF10310.4 KPI39749.1 - 0.083 11.6 2.0 0.16 10.7 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) p450 PF00067.17 KPI39750.1 - 1.6e-61 208.2 0.0 2.3e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.22 KPI39751.1 - 1.3e-32 112.9 0.0 2.1e-26 92.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KPI39751.1 - 6e-22 78.3 13.1 9.2e-22 77.7 9.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KPI39751.1 - 5.7e-08 32.2 1.3 0.0004 19.6 0.0 4.0 4 1 1 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KPI39751.1 - 0.0014 18.6 0.0 1.2 9.0 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KPI39751.1 - 0.0043 17.2 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 KPI39751.1 - 0.012 15.5 0.4 1.5 8.7 0.0 3.3 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 KPI39751.1 - 0.058 13.3 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase TPR_14 PF13428.1 KPI39752.1 - 1.4e-05 25.2 4.5 60 4.6 0.0 7.6 5 3 4 9 9 9 0 Tetratricopeptide repeat Suf PF05843.9 KPI39752.1 - 0.0011 18.7 3.4 0.015 15.0 0.2 2.7 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_16 PF13432.1 KPI39752.1 - 0.0013 19.3 2.1 0.71 10.6 0.0 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat HAT PF02184.11 KPI39752.1 - 0.26 11.0 20.4 2.4 7.9 0.5 6.2 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat AAA_12 PF13087.1 KPI39753.1 - 1.1e-26 93.4 0.0 2e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KPI39753.1 - 7e-25 87.9 0.0 1.6e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KPI39753.1 - 1.7e-08 34.1 0.0 6.2e-08 32.2 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KPI39753.1 - 3.4e-06 26.7 0.0 0.00014 21.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KPI39753.1 - 1.7e-05 24.6 0.0 0.00021 21.1 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KPI39753.1 - 0.0018 18.4 0.0 0.0075 16.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KPI39753.1 - 0.0022 18.1 0.0 0.0066 16.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KPI39753.1 - 0.0039 16.6 0.0 0.0092 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KPI39753.1 - 0.0051 17.1 0.0 0.046 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 KPI39753.1 - 0.0061 15.9 0.1 0.017 14.4 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_5 PF07728.9 KPI39753.1 - 0.0094 15.6 0.0 0.032 13.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) SMC_N PF02463.14 KPI39753.1 - 0.01 15.1 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KPI39753.1 - 0.011 15.7 0.0 0.068 13.1 0.0 2.5 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 KPI39753.1 - 0.017 14.2 0.0 0.038 13.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 KPI39753.1 - 0.03 15.1 0.0 0.37 11.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KPI39753.1 - 0.039 13.4 0.1 0.7 9.3 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.12 KPI39753.1 - 0.064 12.1 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DEAD PF00270.24 KPI39753.1 - 0.069 12.6 0.1 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_33 PF13671.1 KPI39753.1 - 0.082 12.7 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KPI39753.1 - 0.18 11.0 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 KPI39753.1 - 0.19 10.6 0.4 0.46 9.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Abhydrolase_5 PF12695.2 KPI39754.1 - 4.8e-08 32.8 0.0 1.9e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI39754.1 - 3.3e-06 27.1 3.4 8.6e-06 25.7 2.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI39754.1 - 0.11 11.6 0.0 0.28 10.3 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hemerythrin PF01814.18 KPI39755.1 - 1.3e-07 31.7 1.3 2.1e-07 31.1 0.9 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Acyl-CoA_dh_1 PF00441.19 KPI39756.1 - 1.7e-37 128.8 0.4 2.4e-37 128.3 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 KPI39756.1 - 1.2e-17 63.4 0.3 2.2e-17 62.6 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 KPI39756.1 - 1.7e-17 63.9 0.0 4e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KPI39756.1 - 2.3e-12 46.2 1.3 1.5e-11 43.6 0.9 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KPI39756.1 - 1.2e-05 25.5 0.0 2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cys_rich_VLP PF14194.1 KPI39756.1 - 0.16 11.7 0.0 0.42 10.3 0.0 1.7 1 0 0 1 1 1 0 Cysteine-rich VLP WD40 PF00400.27 KPI39757.1 - 1.5e-05 24.6 1.0 0.0011 18.7 0.5 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Nucleoplasmin PF03066.10 KPI39757.1 - 0.02 14.4 2.0 0.055 12.9 1.4 1.8 1 0 0 1 1 1 0 Nucleoplasmin Nucleo_P87 PF07267.6 KPI39757.1 - 0.11 11.1 2.0 0.15 10.7 1.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PBP1_TM PF14812.1 KPI39757.1 - 0.62 10.4 7.9 1.4 9.2 5.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal E1-E2_ATPase PF00122.15 KPI39758.1 - 6e-42 143.2 7.2 6e-42 143.2 5.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KPI39758.1 - 1.3e-05 25.6 0.5 8.3e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KPI39758.1 - 0.017 15.2 0.0 0.053 13.6 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-FPG_IleRS PF06827.9 KPI39759.1 - 0.041 13.5 4.3 0.061 12.9 1.9 2.1 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-CSL PF05207.8 KPI39759.1 - 7.4 6.1 6.3 32 4.1 4.4 2.0 1 1 0 1 1 1 0 CSL zinc finger BTB PF00651.26 KPI39760.1 - 0.0066 16.4 0.0 0.027 14.4 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Utp21 PF04192.7 KPI39762.1 - 0.065 12.3 0.4 0.096 11.7 0.2 1.2 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain RESP18 PF14948.1 KPI39762.1 - 0.28 11.2 3.5 0.32 11.0 0.0 2.3 2 0 0 2 2 2 0 RESP18 domain MFS_1 PF07690.11 KPI39764.1 - 2.2e-35 122.0 28.8 2.2e-35 122.0 20.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily PGG PF13962.1 KPI39764.1 - 1.1 8.9 6.0 15 5.2 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function cobW PF02492.14 KPI39765.1 - 9.1e-37 126.2 0.0 1.4e-36 125.5 0.0 1.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KPI39765.1 - 8.6e-05 22.2 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 KPI39765.1 - 0.0062 16.0 0.0 0.008 15.7 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KPI39765.1 - 0.0072 16.4 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KPI39765.1 - 0.016 14.9 0.1 0.045 13.5 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 KPI39765.1 - 0.021 14.3 0.0 0.24 10.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.1 KPI39765.1 - 0.03 14.6 0.1 0.11 12.8 0.0 1.9 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.1 KPI39765.1 - 0.035 14.0 0.0 0.035 14.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 KPI39765.1 - 0.044 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 KPI39765.1 - 0.046 12.9 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein CbiA PF01656.18 KPI39765.1 - 0.052 12.9 0.0 0.11 11.8 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 KPI39765.1 - 0.056 13.3 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KPI39765.1 - 0.11 12.2 0.1 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.4 KPI39765.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MFS_1 PF07690.11 KPI39766.1 - 9.6e-37 126.5 32.4 1.5e-36 125.9 22.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF485 PF04341.7 KPI39766.1 - 0.26 11.0 0.0 0.26 11.0 0.0 3.6 4 2 1 5 5 5 0 Protein of unknown function, DUF485 Pap_E4 PF02711.9 KPI39767.1 - 0.0034 18.1 2.4 0.0034 18.1 1.7 2.5 3 0 0 3 3 3 1 E4 protein PvlArgDC PF01862.11 KPI39767.1 - 0.2 11.2 2.6 0.18 11.3 0.7 1.7 1 1 1 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Activator_LAG-3 PF11498.3 KPI39767.1 - 0.36 9.5 7.7 0.52 9.0 5.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Fer2_3 PF13085.1 KPI39768.1 - 8e-10 38.5 0.0 2.5e-07 30.5 0.0 2.8 1 1 1 2 2 2 2 2Fe-2S iron-sulfur cluster binding domain Zn_clus PF00172.13 KPI39768.1 - 0.0027 17.5 4.5 0.0027 17.5 3.1 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fer4_8 PF13183.1 KPI39768.1 - 0.0041 17.1 8.0 0.011 15.6 5.5 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 KPI39768.1 - 0.023 15.0 9.0 0.072 13.4 6.3 1.9 1 0 0 1 1 1 0 4Fe-4S dicluster domain ADH_zinc_N PF00107.21 KPI39769.1 - 3.5e-27 94.5 0.3 6.3e-27 93.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI39769.1 - 7.5e-22 77.1 1.1 1.6e-21 76.1 0.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 KPI39769.1 - 1.2e-07 30.7 0.9 1.6e-07 30.3 0.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI39769.1 - 0.022 13.3 0.1 0.032 12.7 0.1 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter Nitroreductase PF00881.19 KPI39771.1 - 2.8e-12 46.7 0.0 4.1e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family Amidoligase_2 PF12224.3 KPI39772.1 - 1.2e-14 54.5 5.8 5.7e-07 29.4 0.9 3.0 1 1 0 2 2 2 2 Putative amidoligase enzyme WD40 PF00400.27 KPI39773.1 - 1.6e-24 84.8 7.7 1.4e-07 31.0 0.0 6.9 7 1 1 8 8 8 4 WD domain, G-beta repeat eIF2A PF08662.6 KPI39773.1 - 0.0011 18.7 0.2 0.03 14.0 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 KPI39773.1 - 0.0061 16.0 0.4 0.024 14.2 0.3 2.0 1 0 0 1 1 1 1 HIRA B motif PSII_BNR PF14870.1 KPI39773.1 - 0.033 13.1 0.0 0.22 10.4 0.0 2.0 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 PD40 PF07676.7 KPI39773.1 - 0.29 10.8 4.3 19 5.0 0.1 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Sugar_tr PF00083.19 KPI39774.1 - 8.9e-74 248.6 28.1 1.2e-73 248.1 19.5 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI39774.1 - 2.9e-08 32.8 45.1 2.9e-08 32.8 31.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Amidohydro_1 PF01979.15 KPI39775.1 - 6.2e-34 118.1 0.0 9.6e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KPI39775.1 - 1.4e-06 28.6 3.8 6.6e-05 23.0 0.6 2.4 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KPI39775.1 - 3.2e-06 26.6 3.6 0.00018 20.8 0.2 2.6 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KPI39775.1 - 0.0024 17.6 0.0 0.007 16.1 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Aminotran_3 PF00202.16 KPI39776.1 - 6.9e-83 278.2 0.0 3.8e-80 269.2 0.0 3.0 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KPI39776.1 - 0.0014 17.8 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KPI39776.1 - 0.059 12.3 0.0 0.17 10.8 0.0 1.8 1 1 1 2 2 2 0 Aminotransferase class I and II Actin PF00022.14 KPI39778.1 - 2.6e-118 394.8 0.0 3.2e-118 394.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KPI39778.1 - 0.015 13.9 0.0 0.14 10.7 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein DnaJ-X PF14308.1 KPI39779.1 - 7.4e-75 250.7 5.0 7.4e-75 250.7 3.5 2.8 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 KPI39779.1 - 9.5e-25 86.1 0.9 4e-24 84.1 0.6 2.2 1 0 0 1 1 1 1 DnaJ domain OrfB_IS605 PF01385.14 KPI39779.1 - 0.0054 16.1 3.0 0.014 14.8 2.1 1.6 1 0 0 1 1 1 1 Probable transposase Ndc1_Nup PF09531.5 KPI39779.1 - 2.1 6.6 3.7 3.7 5.8 2.6 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Parvo_coat PF00740.13 KPI39779.1 - 3.4 6.5 6.3 5.9 5.7 4.3 1.3 1 0 0 1 1 1 0 Parvovirus coat protein VP2 PHD PF00628.24 KPI39780.1 - 1.2e-05 24.9 7.6 2.1e-05 24.1 5.3 1.4 1 0 0 1 1 1 1 PHD-finger Aminotran_3 PF00202.16 KPI39781.1 - 1.9e-14 53.2 0.0 3.2e-10 39.3 0.0 2.8 2 1 0 2 2 2 2 Aminotransferase class-III Amidase PF01425.16 KPI39782.1 - 9.1e-77 258.7 2.6 3.1e-76 256.9 1.8 1.7 1 1 0 1 1 1 1 Amidase Syntaxin_2 PF14523.1 KPI39783.1 - 0.0078 16.2 8.9 13 5.9 1.8 4.8 3 2 1 4 4 4 2 Syntaxin-like protein DUF4510 PF14971.1 KPI39783.1 - 0.058 13.5 3.6 0.093 12.8 1.6 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4510) DUF3037 PF11236.3 KPI39783.1 - 0.12 12.4 1.3 0.43 10.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) IncA PF04156.9 KPI39783.1 - 0.13 11.7 10.7 1.2 8.6 1.2 2.3 2 0 0 2 2 2 0 IncA protein Bacillus_HBL PF05791.6 KPI39783.1 - 0.16 11.3 8.6 0.033 13.5 0.7 2.9 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF465 PF04325.8 KPI39783.1 - 0.19 11.4 4.2 10 5.9 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) NPV_P10 PF05531.7 KPI39783.1 - 0.21 11.8 8.8 4.8 7.4 0.6 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 KPI39783.1 - 0.23 10.6 8.2 0.025 13.7 2.5 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF4404 PF14357.1 KPI39783.1 - 5 7.6 10.3 1.6 9.2 1.7 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4404) CxxCxxCC PF03692.10 KPI39784.1 - 0.038 14.4 0.7 0.16 12.4 0.3 2.1 2 0 0 2 2 2 0 Putative zinc- or iron-chelating domain Glyco_hydro_88 PF07470.8 KPI39785.1 - 7.9e-76 255.2 1.7 9e-76 255.0 1.2 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Prenyltrans_2 PF13249.1 KPI39785.1 - 0.016 15.6 0.4 0.89 9.9 0.0 3.0 1 1 0 2 2 2 0 Prenyltransferase-like SRP40_C PF05022.7 KPI39785.1 - 0.094 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 SRP40, C-terminal domain Prenyltrans PF00432.16 KPI39786.1 - 9.7e-25 85.8 10.7 6.2e-06 25.6 0.4 5.7 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KPI39786.1 - 2e-18 66.8 0.0 4.5e-15 56.0 0.0 2.5 2 0 0 2 2 2 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 KPI39786.1 - 0.00038 20.4 0.0 0.079 12.9 0.0 2.6 1 1 1 2 2 2 2 Prenyltransferase-like MFS_1 PF07690.11 KPI39787.1 - 7.6e-35 120.2 29.3 1.1e-34 119.7 20.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ADH_zinc_N PF00107.21 KPI39788.1 - 8.7e-19 67.3 0.0 1.7e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI39788.1 - 2.6e-16 59.3 0.3 5.7e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PNRC PF15365.1 KPI39789.1 - 0.0058 16.6 1.0 0.03 14.3 0.7 2.3 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator zf-C2H2 PF00096.21 KPI39790.1 - 2.1e-12 46.5 11.2 2.5e-06 27.4 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI39790.1 - 3.7e-10 39.4 9.4 0.00024 21.2 3.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KPI39790.1 - 2.8e-05 24.1 5.5 0.0033 17.5 1.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KPI39790.1 - 2.8e-05 24.1 13.7 0.00026 21.1 4.0 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 KPI39790.1 - 3.7e-05 23.7 3.6 0.003 17.6 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KPI39790.1 - 0.0018 18.1 9.3 0.0025 17.6 0.2 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KPI39790.1 - 0.35 10.9 3.5 4.3 7.5 0.4 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF3774 PF12609.3 KPI39790.1 - 7.5 7.4 10.0 0.43 11.4 2.5 2.3 2 0 0 2 2 2 0 Wound-induced protein XPG_N PF00752.12 KPI39791.1 - 3.3e-34 117.1 0.0 9.8e-34 115.6 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KPI39791.1 - 1.1e-25 89.4 0.0 2.6e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 KPI39791.1 - 0.0018 18.4 0.0 0.0048 17.1 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.15 KPI39791.1 - 0.0041 16.5 2.5 0.0041 16.5 1.7 3.7 3 0 0 3 3 3 1 Ubiquitin interaction motif Beta-lactamase PF00144.19 KPI39792.1 - 2.9e-24 85.7 0.1 4.6e-24 85.0 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase SNF2_N PF00176.18 KPI39792.1 - 0.02 13.6 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain G-patch PF01585.18 KPI39793.1 - 1.5e-06 27.9 1.2 6.9e-06 25.7 0.1 2.6 2 1 0 2 2 2 1 G-patch domain Phage_GPD PF05954.6 KPI39793.1 - 5.4 6.1 12.9 0.061 12.5 3.0 2.0 1 1 1 2 2 2 0 Phage late control gene D protein (GPD) Rrn6 PF10214.4 KPI39793.1 - 9.2 4.2 18.4 13 3.6 12.7 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Hydrolase PF00702.21 KPI39795.1 - 1.8e-14 54.6 0.6 2.3e-14 54.3 0.4 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KPI39795.1 - 7.7e-11 42.5 0.0 1.2e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KPI39795.1 - 0.001 18.6 0.2 0.43 10.0 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KPI39795.1 - 0.041 14.0 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.3 KPI39796.1 - 1.3e-07 30.6 0.1 0.0001 21.0 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain WD40 PF00400.27 KPI39799.1 - 3.6e-16 58.3 23.6 8.7e-07 28.5 0.6 9.8 11 0 0 11 11 11 6 WD domain, G-beta repeat Zip PF02535.17 KPI39800.1 - 3.1e-37 128.2 10.4 3.1e-37 128.2 7.2 1.8 2 0 0 2 2 2 1 ZIP Zinc transporter Thyroglobulin_1 PF00086.13 KPI39800.1 - 0.55 9.6 2.7 11 5.4 0.0 2.9 4 0 0 4 4 4 0 Thyroglobulin type-1 repeat Zn_clus PF00172.13 KPI39801.1 - 0.13 12.1 11.6 0.25 11.2 8.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_5 PF07994.7 KPI39802.1 - 2.8e-113 378.2 0.1 3.4e-113 378.0 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KPI39802.1 - 6.2e-46 154.8 0.6 1.3e-45 153.8 0.4 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF2733 PF10813.3 KPI39803.1 - 0.011 15.2 0.8 0.032 13.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) Glyco_trans_2_3 PF13632.1 KPI39804.1 - 3e-46 157.5 2.3 3e-46 157.5 1.6 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KPI39804.1 - 7.8e-07 29.1 0.1 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KPI39804.1 - 0.0002 21.0 0.0 0.0012 18.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KPI39804.1 - 0.005 16.1 0.0 0.015 14.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 21 zf-Apc11 PF12861.2 KPI39807.1 - 8.2e-39 131.3 6.8 1e-38 131.0 4.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KPI39807.1 - 3.1e-25 88.0 5.9 4e-25 87.6 4.1 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KPI39807.1 - 7.1e-06 25.7 19.0 6.9e-05 22.6 13.1 2.4 1 1 0 1 1 1 1 Ring finger domain DUF2256 PF10013.4 KPI39807.1 - 0.003 17.2 0.8 0.003 17.2 0.5 2.5 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C3HC4 PF00097.20 KPI39807.1 - 0.0039 16.8 11.2 0.011 15.3 7.8 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KPI39807.1 - 0.0043 16.6 14.6 0.16 11.6 10.1 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KPI39807.1 - 0.018 14.5 12.8 0.027 14.0 1.5 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 KPI39807.1 - 0.033 14.1 13.5 0.15 12.0 9.4 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI39807.1 - 0.066 12.9 13.8 0.6 9.8 9.6 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-HIT PF04438.11 KPI39807.1 - 0.31 10.7 5.4 0.37 10.4 1.1 2.2 2 0 0 2 2 2 0 HIT zinc finger DUF329 PF03884.9 KPI39807.1 - 0.78 9.3 6.0 1.6 8.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-HC5HC2H_2 PF13832.1 KPI39807.1 - 0.84 9.6 5.1 0.36 10.8 1.9 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 KPI39807.1 - 0.93 9.4 15.7 31 4.6 10.9 3.1 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 KPI39807.1 - 1.1 9.0 11.9 3.4 7.4 8.3 1.9 1 1 0 1 1 1 0 PHD-finger zf-Nse PF11789.3 KPI39807.1 - 1.2 8.7 5.0 1.8 8.1 3.5 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.2 KPI39807.1 - 3.4 7.5 9.4 8.1 6.3 2.9 2.2 1 1 1 2 2 2 0 Double zinc ribbon RINGv PF12906.2 KPI39807.1 - 4.1 7.5 9.5 1.3 9.0 4.3 1.9 2 1 0 2 2 2 0 RING-variant domain zf-HC5HC2H PF13771.1 KPI39807.1 - 6.8 6.9 8.3 26 5.0 5.7 1.9 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 KPI39807.1 - 8.9 6.4 11.7 30 4.6 8.1 1.9 1 1 0 1 1 1 0 RING-like domain ESSS PF10183.4 KPI39808.1 - 1e-20 74.0 0.3 1.2e-20 73.8 0.2 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) AAA PF00004.24 KPI39809.1 - 5.5e-43 146.3 0.0 8.9e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KPI39809.1 - 1.9e-07 31.2 0.0 1.3e-05 25.2 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 KPI39809.1 - 1.8e-06 27.7 0.0 4.2e-05 23.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KPI39809.1 - 2.1e-06 27.7 0.0 6.6e-06 26.1 0.0 1.9 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KPI39809.1 - 2.3e-06 27.7 0.0 0.00088 19.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 KPI39809.1 - 8.3e-06 25.0 0.0 1.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 KPI39809.1 - 0.00029 19.8 0.0 0.00083 18.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KPI39809.1 - 0.00038 21.2 0.4 0.0012 19.6 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KPI39809.1 - 0.00043 19.9 0.0 0.00096 18.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KPI39809.1 - 0.0012 18.7 0.0 0.0055 16.5 0.0 2.1 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.8 KPI39809.1 - 0.0014 17.4 0.0 0.0027 16.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 KPI39809.1 - 0.0017 18.2 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KPI39809.1 - 0.0028 17.9 0.0 0.0074 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KPI39809.1 - 0.0029 17.0 0.0 0.0064 15.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KPI39809.1 - 0.0032 16.6 0.0 0.0067 15.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KPI39809.1 - 0.0056 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF4200 PF13863.1 KPI39809.1 - 0.0062 16.4 0.5 0.017 15.0 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) AAA_25 PF13481.1 KPI39809.1 - 0.0068 15.8 0.1 0.04 13.3 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 KPI39809.1 - 0.0071 15.9 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KPI39809.1 - 0.0085 15.5 0.0 0.029 13.8 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 KPI39809.1 - 0.0097 16.0 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 KPI39809.1 - 0.018 14.5 0.1 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KPI39809.1 - 0.025 14.5 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 KPI39809.1 - 0.027 14.3 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit KaiC PF06745.8 KPI39809.1 - 0.031 13.3 0.2 0.12 11.4 0.0 2.0 3 0 0 3 3 3 0 KaiC UPF0079 PF02367.12 KPI39809.1 - 0.035 13.7 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KPI39809.1 - 0.037 13.7 0.0 0.14 11.8 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase PhoH PF02562.11 KPI39809.1 - 0.037 13.2 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.1 KPI39809.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 KPI39809.1 - 0.052 13.1 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 KPI39809.1 - 0.088 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 KPI39809.1 - 0.091 12.3 0.1 0.34 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KPI39809.1 - 0.17 12.1 1.1 3.8 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 KPI39810.1 - 8.8e-25 87.1 60.2 1e-18 67.1 30.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.16 KPI39811.1 - 9.7e-13 48.0 0.0 2e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI39811.1 - 9.8e-11 40.8 0.1 1.5e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KPI39811.1 - 1.9e-09 37.7 0.5 3e-09 37.1 0.3 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KPI39811.1 - 5e-07 28.8 0.0 3.3e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.8 KPI39811.1 - 0.00053 19.3 0.2 0.00081 18.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family VanZ PF04892.7 KPI39812.1 - 3.5e-11 43.1 0.4 4.6e-11 42.7 0.3 1.2 1 0 0 1 1 1 1 VanZ like family DUF4401 PF14351.1 KPI39812.1 - 0.041 12.8 2.0 0.07 12.1 1.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) DUF4345 PF14248.1 KPI39812.1 - 0.14 11.5 2.8 0.49 9.8 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) Asp PF00026.18 KPI39813.1 - 4.5e-80 269.2 5.9 5.2e-80 269.0 4.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KPI39813.1 - 9.6e-06 26.0 1.0 0.0053 17.2 0.2 2.9 2 1 0 2 2 2 2 Aspartyl protease Ala_racemase_N PF01168.15 KPI39814.1 - 9.5e-37 126.6 0.0 2.1e-36 125.5 0.0 1.5 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain MFS_1 PF07690.11 KPI39815.1 - 1.2e-40 139.2 34.0 1.2e-40 139.2 23.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI39815.1 - 4.4e-19 68.4 24.0 8.1e-19 67.5 16.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KPI39815.1 - 3.1e-08 32.3 2.6 3.1e-08 32.3 1.8 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2254 PF10011.4 KPI39815.1 - 0.43 8.9 4.1 0.75 8.1 2.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) PAP2 PF01569.16 KPI39815.1 - 4.2 7.0 15.1 0.024 14.3 2.1 3.0 2 2 0 2 2 2 0 PAP2 superfamily CPSase_L_D2 PF02786.12 KPI39818.1 - 5.7e-64 215.2 0.9 6e-55 185.7 0.3 2.3 1 1 1 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KPI39818.1 - 1.1e-34 118.8 0.0 2.9e-34 117.4 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KPI39818.1 - 2e-30 104.9 0.0 3.8e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATPgrasp_Ter PF15632.1 KPI39818.1 - 1.1e-10 40.7 0.0 0.00018 20.3 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 KPI39818.1 - 2e-10 40.7 0.3 1.1e-09 38.2 0.2 2.1 1 1 0 1 1 1 1 ATP-grasp domain HMGL-like PF00682.14 KPI39818.1 - 5.9e-07 29.3 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 HMGL-like RimK PF08443.6 KPI39818.1 - 0.012 15.1 0.1 3.4 7.1 0.1 2.4 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 KPI39818.1 - 0.018 14.4 0.0 0.044 13.1 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Mur_ligase_M PF08245.7 KPI39819.1 - 1.2e-06 28.7 0.1 2.2e-05 24.6 0.1 2.7 1 1 0 1 1 1 1 Mur ligase middle domain FKBP_C PF00254.23 KPI39821.1 - 4.9e-26 90.5 0.0 9.1e-26 89.7 0.0 1.4 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ank_2 PF12796.2 KPI39824.1 - 2.9e-13 49.9 1.0 9.1e-05 22.7 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KPI39824.1 - 1.9e-10 40.0 8.8 0.0005 19.7 0.1 5.1 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 KPI39824.1 - 4.3e-09 36.3 7.0 0.0055 16.9 0.1 5.1 6 1 1 7 7 5 2 Ankyrin repeats (many copies) NACHT PF05729.7 KPI39824.1 - 2.9e-07 30.2 0.0 6.9e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.1 KPI39824.1 - 3.7e-07 30.4 4.4 0.35 11.4 0.0 5.5 5 1 1 6 6 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI39824.1 - 4.2e-06 26.4 1.2 0.29 11.4 0.1 5.3 6 0 0 6 6 5 2 Ankyrin repeat AAA_16 PF13191.1 KPI39824.1 - 0.00065 19.7 3.4 0.002 18.1 0.0 3.3 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 KPI39824.1 - 0.0011 19.0 0.2 0.01 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KPI39824.1 - 0.0034 18.1 1.3 0.02 15.6 0.0 3.0 3 0 0 3 3 1 1 AAA domain NB-ARC PF00931.17 KPI39824.1 - 0.0055 15.5 1.1 0.011 14.6 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 KPI39824.1 - 0.028 14.1 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 KPI39824.1 - 0.028 14.2 0.0 1 9.3 0.0 2.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KPI39824.1 - 0.036 13.8 0.0 0.13 12.0 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 KPI39824.1 - 0.066 13.0 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KPI39824.1 - 0.07 12.8 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 KPI39824.1 - 0.2 11.4 1.5 9.5 5.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 Phage_P2_GpE PF06528.7 KPI39826.1 - 0.025 14.0 0.4 0.067 12.6 0.3 1.7 1 0 0 1 1 1 0 Phage P2 GpE NIPSNAP PF07978.8 KPI39826.1 - 0.029 14.3 0.1 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 NIPSNAP Phage_holin PF04688.8 KPI39826.1 - 5.8 6.5 5.9 16 5.0 0.4 2.4 2 0 0 2 2 2 0 Phage lysis protein, holin Fungal_trans PF04082.13 KPI39827.1 - 1.3e-07 30.8 1.0 2.5e-07 29.8 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4106 PF13388.1 KPI39827.1 - 0.32 9.8 1.3 0.48 9.3 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) HEAT PF02985.17 KPI39829.1 - 1.3e-23 80.9 7.5 0.0021 18.0 0.0 12.1 13 0 0 13 13 12 4 HEAT repeat HEAT_2 PF13646.1 KPI39829.1 - 8.7e-19 67.5 14.7 4.1e-07 30.1 0.1 9.0 5 3 5 10 10 10 5 HEAT repeats HEAT_EZ PF13513.1 KPI39829.1 - 1.2e-14 54.2 19.5 2.8e-05 24.4 0.0 10.7 8 2 5 13 13 12 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KPI39829.1 - 2.9e-10 40.3 0.1 0.037 14.3 0.0 6.3 3 3 3 6 6 6 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KPI39829.1 - 2.8e-09 36.6 1.3 0.0035 16.7 0.1 6.1 5 2 2 7 7 7 2 CLASP N terminal Adaptin_N PF01602.15 KPI39829.1 - 9.9e-07 27.4 2.1 0.029 12.7 0.1 4.1 3 1 1 5 5 5 3 Adaptin N terminal region Arm PF00514.18 KPI39829.1 - 1.7e-06 27.6 8.1 0.92 9.4 0.0 6.2 6 0 0 6 6 5 2 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 KPI39829.1 - 1.5e-05 24.7 0.1 0.072 12.7 0.0 5.0 4 1 2 6 6 6 2 rRNA processing/ribosome biogenesis Cnd1 PF12717.2 KPI39829.1 - 0.00015 21.6 5.3 0.41 10.4 0.5 5.3 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 KPI39829.1 - 0.00031 19.5 6.6 0.002 16.9 0.2 4.1 3 2 1 4 4 4 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.3 KPI39829.1 - 0.0013 18.7 0.2 4 7.3 0.0 4.1 3 1 0 4 4 4 1 Domain of unknown function (DUF3385) TFCD_C PF12612.3 KPI39829.1 - 0.0016 17.9 3.3 0.37 10.1 0.0 4.3 5 0 0 5 5 5 1 Tubulin folding cofactor D C terminal DUF4042 PF13251.1 KPI39829.1 - 0.0028 17.1 0.2 11 5.4 0.0 4.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4042) Proteasom_PSMB PF10508.4 KPI39829.1 - 0.003 15.9 2.3 0.017 13.4 0.0 3.1 3 1 1 4 4 4 1 Proteasome non-ATPase 26S subunit IBN_N PF03810.14 KPI39829.1 - 0.0041 17.0 1.0 0.069 13.0 0.0 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF2435 PF10363.4 KPI39829.1 - 0.007 16.2 1.1 0.086 12.7 0.2 3.3 5 0 0 5 5 2 1 Protein of unknown function (DUF2435) V-ATPase_H_N PF03224.9 KPI39829.1 - 0.018 14.2 5.2 0.54 9.3 0.0 3.8 3 1 0 3 3 3 0 V-ATPase subunit H MFS_1 PF07690.11 KPI39830.1 - 7.3e-30 103.8 27.7 7.7e-30 103.7 18.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KPI39830.1 - 0.72 9.6 6.8 0.25 11.1 1.6 2.5 3 0 0 3 3 3 0 MFS_1 like family Pil1 PF13805.1 KPI39831.1 - 2.7e-154 512.1 0.0 3.4e-154 511.7 0.0 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 KPI39831.1 - 0.0075 15.6 2.7 0.011 15.1 0.8 1.9 1 1 1 2 2 2 1 FAM92 protein Peptidase_S10 PF00450.17 KPI39832.1 - 1.9e-58 198.6 0.0 4.9e-58 197.2 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KPI39832.1 - 0.00069 19.5 0.0 0.72 9.6 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family OGFr_N PF04664.8 KPI39833.1 - 8.5e-23 80.7 0.0 1.1e-11 44.5 0.0 2.0 1 1 1 2 2 2 2 Opioid growth factor receptor (OGFr) conserved region Kelch_5 PF13854.1 KPI39834.1 - 8.5e-19 67.0 6.6 3.2e-15 55.6 0.2 4.7 4 0 0 4 4 4 2 Kelch motif SKG6 PF08693.5 KPI39834.1 - 1.9e-08 33.5 1.1 3.9e-08 32.4 0.8 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_3 PF13415.1 KPI39834.1 - 2.8e-08 33.7 12.6 1.3e-06 28.3 0.4 6.2 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_1 PF01344.20 KPI39834.1 - 2.6e-07 30.0 2.8 0.012 15.1 0.6 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 KPI39834.1 - 3.4e-07 29.9 3.1 0.00024 20.7 0.3 5.2 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_6 PF13964.1 KPI39834.1 - 0.0029 17.7 5.0 0.022 14.9 0.7 3.9 2 1 1 3 3 3 1 Kelch motif Kelch_2 PF07646.10 KPI39834.1 - 0.0058 16.3 4.7 7 6.5 0.2 4.6 4 1 0 4 4 4 1 Kelch motif Aldo_ket_red PF00248.16 KPI39835.1 - 6.9e-52 176.0 0.0 8e-52 175.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LIM PF00412.17 KPI39837.1 - 7.7e-21 73.9 16.8 4.6e-11 42.6 4.8 2.3 2 0 0 2 2 2 2 LIM domain CMD PF02627.15 KPI39838.1 - 6e-20 70.8 0.1 9.7e-20 70.2 0.1 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family TFX_C PF14601.1 KPI39838.1 - 0.005 16.5 0.0 0.0083 15.8 0.0 1.3 1 0 0 1 1 1 1 DNA_binding protein, TFX, C-term F-box PF00646.28 KPI39839.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 F-box domain HET PF06985.6 KPI39840.1 - 2.3e-22 79.6 0.4 4.4e-22 78.7 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) eIF3_subunit PF08597.5 KPI39841.1 - 5e-55 186.7 24.5 6.2e-55 186.4 17.0 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Ycf1 PF05758.7 KPI39841.1 - 6.9 4.2 7.3 7.4 4.1 5.1 1.3 1 0 0 1 1 1 0 Ycf1 Aldo_ket_red PF00248.16 KPI39842.1 - 1.7e-56 191.1 0.0 1.9e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_1 PF00583.19 KPI39843.1 - 0.042 13.8 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Lactamase_B PF00753.22 KPI39844.1 - 1.5e-12 47.6 1.1 2.3e-12 46.9 0.8 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI39844.1 - 0.0019 17.7 0.2 0.0022 17.5 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain An_peroxidase PF03098.10 KPI39845.1 - 3.9e-80 269.7 0.0 4.9e-64 216.6 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase bZIP_1 PF00170.16 KPI39846.1 - 1.8e-06 27.8 13.4 1.7e-05 24.7 9.3 2.0 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KPI39846.1 - 0.00059 19.6 8.7 0.00059 19.6 6.0 2.1 1 1 1 2 2 2 1 Basic region leucine zipper TSC22 PF01166.13 KPI39846.1 - 0.049 13.5 0.2 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF724 PF05266.9 KPI39846.1 - 0.063 12.8 3.9 0.083 12.5 2.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) GvpL_GvpF PF06386.6 KPI39846.1 - 0.28 10.7 2.4 0.37 10.3 1.7 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF CENP-F_leu_zip PF10473.4 KPI39846.1 - 0.29 10.9 5.0 0.6 9.9 3.5 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_Maf PF03131.12 KPI39846.1 - 0.31 11.3 9.4 0.5 10.6 6.5 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF1875 PF08961.5 KPI39846.1 - 2 7.6 7.3 1.5 8.1 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) Metallophos PF00149.23 KPI39847.1 - 2.5e-38 131.4 0.5 3.2e-38 131.1 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Med17 PF10156.4 KPI39848.1 - 1.2e-55 188.6 0.0 1.7e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DUF2157 PF09925.4 KPI39849.1 - 0.0019 17.8 1.6 0.82 9.2 0.2 3.2 3 0 0 3 3 3 2 Predicted membrane protein (DUF2157) TENA_THI-4 PF03070.11 KPI39850.1 - 0.034 13.9 0.4 0.045 13.4 0.3 1.2 1 0 0 1 1 1 0 TENA/THI-4/PQQC family DUF3510 PF12022.3 KPI39850.1 - 0.046 13.8 0.4 0.098 12.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) PXA PF02194.10 KPI39850.1 - 0.34 10.4 3.1 0.22 11.0 0.8 1.6 1 1 0 1 1 1 0 PXA domain DUF1788 PF08747.6 KPI39850.1 - 0.91 9.4 7.5 0.34 10.7 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1788) PCRF PF03462.13 KPI39850.1 - 4 7.1 6.1 1.2 8.8 0.1 2.5 3 0 0 3 3 3 0 PCRF domain DUF16 PF01519.11 KPI39850.1 - 5.9 7.1 7.7 5.2 7.3 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 HEAT PF02985.17 KPI39851.1 - 0.0056 16.6 6.9 2.6 8.3 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat VPS28 PF03997.7 KPI39851.1 - 0.037 13.6 0.1 0.42 10.1 0.1 2.5 2 0 0 2 2 2 0 VPS28 protein HEAT_EZ PF13513.1 KPI39851.1 - 0.16 12.5 11.2 7.6 7.1 0.0 6.2 6 0 0 6 6 6 0 HEAT-like repeat COG4 PF08318.7 KPI39853.1 - 1.1e-104 349.7 0.0 1.8e-104 349.0 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein Peptidase_M3_N PF08439.5 KPI39853.1 - 0.12 12.4 0.0 0.48 10.4 0.0 2.1 1 0 0 1 1 1 0 Oligopeptidase F SIR2 PF02146.12 KPI39854.1 - 8.7e-57 191.7 0.0 1.3e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Lzipper-MIP1 PF14389.1 KPI39854.1 - 0.063 13.3 0.7 0.12 12.5 0.5 1.4 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Mago-bind PF09282.5 KPI39855.1 - 2e-12 46.4 3.9 2e-12 46.4 2.7 1.8 2 0 0 2 2 2 1 Mago binding DUF2927 PF11150.3 KPI39855.1 - 0.009 15.7 0.4 0.013 15.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2927) Mon1 PF03164.9 KPI39856.1 - 1.1e-103 347.0 0.1 1.8e-71 240.9 0.0 2.1 1 1 1 2 2 2 2 Trafficking protein Mon1 HECT PF00632.20 KPI39857.1 - 1e-52 179.2 0.0 4.5e-52 177.1 0.0 1.9 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Tim17 PF02466.14 KPI39857.1 - 3e-32 111.3 5.9 5.7e-32 110.4 4.1 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family adh_short_C2 PF13561.1 KPI39858.1 - 3e-23 82.8 0.0 3.6e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI39858.1 - 1e-16 61.2 2.1 1.3e-16 60.9 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Mucin PF01456.12 KPI39859.1 - 0.061 13.1 2.0 0.12 12.1 1.4 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein GTP_EFTU PF00009.22 KPI39861.1 - 2.4e-48 164.0 0.0 4.4e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 KPI39861.1 - 5.1e-20 71.3 4.5 1.1e-19 70.3 3.1 1.6 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 KPI39861.1 - 2.3e-07 30.7 0.0 5.8e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KPI39861.1 - 0.0017 18.8 0.0 0.0059 17.0 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU_D3 PF03143.12 KPI39861.1 - 0.0024 17.9 0.4 0.079 13.1 0.6 2.7 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KPI39861.1 - 0.0074 16.3 0.3 0.031 14.3 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu domain 2 Arf PF00025.16 KPI39861.1 - 0.022 13.9 0.0 5 6.3 0.0 2.3 1 1 1 2 2 2 0 ADP-ribosylation factor family SRPRB PF09439.5 KPI39861.1 - 0.027 13.7 0.0 1.5 8.0 0.0 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Peptidase_M28 PF04389.12 KPI39862.1 - 2.5e-24 85.9 0.1 5.8e-24 84.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KPI39862.1 - 3.3e-06 26.7 0.0 4.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 fn3 PF00041.16 KPI39862.1 - 0.006 16.6 2.2 0.0086 16.1 0.3 2.0 2 0 0 2 2 2 1 Fibronectin type III domain Peptidase_M42 PF05343.9 KPI39862.1 - 0.2 10.3 0.0 0.35 9.6 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Lipase_3 PF01764.20 KPI39863.1 - 1.3e-17 63.6 0.0 2.4e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF1937 PF09152.5 KPI39863.1 - 0.057 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1937) PGAP1 PF07819.8 KPI39863.1 - 0.095 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 KPI39863.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family TFIIIC_sub6 PF10419.4 KPI39866.1 - 4e-09 35.7 0.0 7.2e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit Rgp1 PF08737.5 KPI39866.1 - 0.094 11.7 0.5 0.14 11.2 0.0 1.5 2 0 0 2 2 2 0 Rgp1 Vfa1 PF08432.5 KPI39866.1 - 0.44 10.5 5.4 2.3 8.2 0.2 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Cwf_Cwc_15 PF04889.7 KPI39866.1 - 1.6 8.3 14.4 0.18 11.5 1.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF3449 PF11931.3 KPI39866.1 - 3.1 7.2 5.6 1.3 8.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) tRNA-synt_2 PF00152.15 KPI39867.1 - 2.2e-09 36.5 0.0 3.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KPI39867.1 - 0.0026 17.5 0.0 0.0062 16.3 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1565 PF07602.6 KPI39867.1 - 0.039 13.1 0.1 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) PPE PF00823.14 KPI39867.1 - 0.045 13.5 0.2 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 PPE family zf-CHY PF05495.7 KPI39868.1 - 5.2e-16 58.5 14.1 5.2e-16 58.5 9.8 4.4 4 1 1 5 5 5 2 CHY zinc finger RP-C_C PF11800.3 KPI39868.1 - 0.55 9.8 8.1 0.26 10.9 0.3 2.9 2 1 1 3 3 3 0 Replication protein C C-terminal region DEAD PF00270.24 KPI39869.1 - 1.5e-42 144.9 0.0 5.6e-42 143.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI39869.1 - 2.4e-22 78.5 0.2 1.4e-21 76.0 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI39869.1 - 4.3e-07 29.9 0.0 1.2e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 KPI39869.1 - 8.3e-05 21.1 0.1 0.0016 16.9 0.1 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1253) SNF2_N PF00176.18 KPI39869.1 - 0.00017 20.5 0.0 0.00031 19.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 KPI39869.1 - 0.15 12.2 3.7 0.16 12.1 0.3 2.7 3 1 0 3 3 3 0 AAA domain mRNA_cap_enzyme PF01331.14 KPI39870.1 - 2.7e-52 177.2 0.2 3.5e-52 176.8 0.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KPI39870.1 - 1.9e-18 66.6 0.1 2e-10 40.9 0.0 2.8 3 0 0 3 3 3 2 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KPI39870.1 - 4.7e-09 35.8 0.0 1.5e-07 30.9 0.0 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Abhydrolase_6 PF12697.2 KPI39871.1 - 1.8e-18 67.2 0.0 2.3e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI39871.1 - 6.1e-07 29.2 0.0 1.1e-06 28.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI39871.1 - 0.059 12.9 0.0 1 8.8 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold MFS_1 PF07690.11 KPI39872.1 - 1.2e-29 103.1 46.4 1.2e-29 103.1 32.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI39872.1 - 0.00048 18.8 4.7 0.00048 18.8 3.2 3.5 2 1 1 3 3 3 2 Sugar (and other) transporter ELFV_dehydrog PF00208.16 KPI39873.1 - 4.4e-60 203.2 0.0 8.9e-60 202.2 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KPI39873.1 - 1.1e-16 59.5 0.1 2.8e-11 41.6 0.0 2.3 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase DUF4573 PF15140.1 KPI39873.1 - 0.014 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) ELFV_dehydrog_N PF02812.13 KPI39873.1 - 0.05 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Methyltransf_31 PF13847.1 KPI39874.1 - 3.2e-10 39.7 0.0 5.3e-10 39.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI39874.1 - 4.1e-10 40.2 0.1 9.2e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI39874.1 - 1.4e-09 38.2 0.0 2.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI39874.1 - 5.8e-07 29.9 0.0 9e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI39874.1 - 7.7e-07 29.4 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI39874.1 - 1.8e-06 27.7 0.0 2.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI39874.1 - 0.00016 20.8 0.0 0.00022 20.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KPI39874.1 - 0.00069 19.6 0.2 0.0012 18.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KPI39874.1 - 0.025 14.0 0.1 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 KPI39874.1 - 0.052 12.9 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.17 KPI39876.1 - 2.9e-59 200.8 0.0 3.6e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 KPI39877.1 - 4e-11 43.2 1.0 7.6e-11 42.3 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI39877.1 - 0.0056 16.4 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI39877.1 - 0.036 13.6 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 KPI39877.1 - 0.18 11.2 0.0 0.55 9.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase Ribosomal_L12 PF00542.14 KPI39878.1 - 4.1e-13 49.1 9.1 4.2e-12 45.8 5.1 2.5 2 1 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain DUF2575 PF10837.3 KPI39879.1 - 0.041 13.9 0.1 0.14 12.2 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2575) DUF3816 PF12822.2 KPI39879.1 - 0.16 11.8 4.0 0.47 10.3 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) Solute_trans_a PF03619.11 KPI39880.1 - 8.9e-21 74.4 18.3 1e-19 70.8 12.7 2.0 1 1 0 1 1 1 1 Organic solute transporter Ostalpha PrgI PF12666.2 KPI39880.1 - 4.3 7.5 10.4 0.09 12.9 0.6 2.8 1 1 1 3 3 3 0 PrgI family protein ATP-grasp PF02222.17 KPI39881.1 - 4.3e-51 172.6 0.0 8.2e-51 171.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KPI39881.1 - 4.8e-07 29.7 0.0 1.8e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain 2-Hacid_dh_C PF02826.14 KPI39881.1 - 0.00055 19.1 0.0 0.001 18.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.1 KPI39881.1 - 0.0015 18.8 0.1 0.0037 17.5 0.1 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain Dala_Dala_lig_C PF07478.8 KPI39881.1 - 0.0023 17.3 0.0 0.0097 15.3 0.0 1.9 1 1 1 2 2 2 1 D-ala D-ala ligase C-terminus AlaDh_PNT_C PF01262.16 KPI39881.1 - 0.014 14.9 1.1 0.034 13.7 0.2 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 KPI39881.1 - 0.023 14.5 0.0 0.054 13.3 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Rubredoxin PF00301.15 KPI39881.1 - 0.034 14.0 0.1 0.95 9.3 0.0 2.3 2 0 0 2 2 2 0 Rubredoxin 3HCDH_N PF02737.13 KPI39881.1 - 0.07 12.7 2.2 0.072 12.7 0.4 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sgf11 PF08209.6 KPI39882.1 - 0.085 12.1 0.1 0.18 11.1 0.1 1.6 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Ank_3 PF13606.1 KPI39882.1 - 0.13 12.5 0.0 0.47 10.8 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeat zf-RING_2 PF13639.1 KPI39882.1 - 0.3 10.9 8.6 0.055 13.2 3.1 1.9 2 0 0 2 2 2 0 Ring finger domain F-box-like PF12937.2 KPI39883.1 - 0.11 12.2 0.4 0.74 9.5 0.3 2.2 1 1 0 1 1 1 0 F-box-like EF_assoc_2 PF08356.7 KPI39884.1 - 4.5e-33 112.8 0.0 7.8e-33 112.0 0.0 1.4 1 0 0 1 1 1 1 EF hand associated Miro PF08477.8 KPI39884.1 - 7.9e-33 113.4 0.0 8.9e-16 58.4 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 KPI39884.1 - 7.2e-29 98.9 0.4 1.5e-28 97.8 0.1 1.7 2 0 0 2 2 1 1 EF hand associated Ras PF00071.17 KPI39884.1 - 6.3e-25 87.4 0.0 1.3e-15 57.1 0.0 2.2 2 0 0 2 2 2 2 Ras family Fungal_trans PF04082.13 KPI39884.1 - 8.2e-09 34.7 0.0 1.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MMR_HSR1 PF01926.18 KPI39884.1 - 7.1e-08 32.4 0.0 0.0074 16.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 KPI39884.1 - 6.3e-05 22.8 0.4 0.02 14.7 0.3 2.6 2 1 0 2 2 2 1 Dynamin family EF-hand_1 PF00036.27 KPI39884.1 - 0.0002 20.4 5.1 0.1 11.9 0.4 3.3 3 0 0 3 3 3 2 EF hand MobB PF03205.9 KPI39884.1 - 0.00026 20.7 0.1 0.077 12.6 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_7 PF13499.1 KPI39884.1 - 0.0011 19.0 1.2 0.96 9.6 0.2 2.9 2 0 0 2 2 2 1 EF-hand domain pair AAA_16 PF13191.1 KPI39884.1 - 0.0013 18.7 0.2 0.54 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KPI39884.1 - 0.007 16.5 0.0 4.6 7.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain GBP PF02263.14 KPI39884.1 - 0.0086 15.1 0.0 0.051 12.6 0.0 1.9 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain EF-hand_8 PF13833.1 KPI39884.1 - 0.012 15.2 0.3 6.6 6.4 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain pair GTP_EFTU PF00009.22 KPI39884.1 - 0.018 14.5 0.1 9 5.6 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain EF-hand_10 PF14788.1 KPI39884.1 - 0.021 14.4 0.3 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 KPI39884.1 - 0.023 14.5 6.4 0.2 11.6 0.4 3.4 3 0 0 3 3 2 0 EF-hand domain AIG1 PF04548.11 KPI39884.1 - 0.026 13.6 0.0 0.052 12.6 0.0 1.5 1 0 0 1 1 1 0 AIG1 family ABC_tran PF00005.22 KPI39884.1 - 0.031 14.5 0.0 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Trp_oprn_chp PF09534.5 KPI39884.1 - 0.042 13.4 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Arf PF00025.16 KPI39884.1 - 0.045 12.9 0.2 28 3.9 0.0 3.5 4 0 0 4 4 3 0 ADP-ribosylation factor family AAA_29 PF13555.1 KPI39884.1 - 0.05 13.1 0.1 7.9 6.1 0.1 2.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.1 KPI39884.1 - 0.06 13.2 0.0 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KPI39884.1 - 0.11 11.9 0.0 4.4 6.6 0.0 2.7 3 0 0 3 3 2 0 AAA-like domain VirE PF05272.6 KPI39884.1 - 0.14 11.6 0.1 22 4.4 0.0 3.0 3 0 0 3 3 3 0 Virulence-associated protein E AAA_24 PF13479.1 KPI39884.1 - 0.14 11.7 0.1 0.81 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KPI39884.1 - 0.17 12.0 0.0 11 6.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase EF-hand_5 PF13202.1 KPI39884.1 - 0.23 10.8 7.5 2.7 7.4 0.3 3.4 3 0 0 3 3 3 0 EF hand IIGP PF05049.8 KPI39884.1 - 0.29 9.9 0.1 0.49 9.1 0.1 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Septin PF00735.13 KPI39884.1 - 0.34 9.8 0.0 0.68 8.8 0.0 1.4 2 0 0 2 2 1 0 Septin SRPRB PF09439.5 KPI39884.1 - 0.42 9.8 0.7 27 3.9 0.0 2.6 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Amidohydro_3 PF07969.6 KPI39885.1 - 5.4e-23 81.8 0.4 6.8e-23 81.5 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family D-aminoacyl_C PF07908.7 KPI39885.1 - 1e-17 63.1 0.2 2.2e-17 62.0 0.1 1.6 1 0 0 1 1 1 1 D-aminoacylase, C-terminal region Amidohydro_5 PF13594.1 KPI39885.1 - 3.3e-11 42.8 0.3 8.2e-11 41.5 0.2 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KPI39885.1 - 3.5e-09 37.0 0.3 0.0015 18.6 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase Amidohydro_1 PF01979.15 KPI39885.1 - 0.00082 19.1 3.4 0.16 11.5 0.0 3.0 2 1 1 3 3 3 2 Amidohydrolase family BTB PF00651.26 KPI39886.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain NfeD PF01957.13 KPI39887.1 - 0.22 11.6 0.9 0.52 10.4 0.0 1.8 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding RRM_1 PF00076.17 KPI39888.1 - 4.2e-26 90.3 0.3 1.7e-09 37.1 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI39888.1 - 5.4e-18 64.7 0.0 0.00015 21.6 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI39888.1 - 3.7e-13 49.1 0.0 2.1e-06 27.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amino_oxidase PF01593.19 KPI39889.1 - 1.1e-26 93.8 0.1 1.3e-26 93.7 0.1 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase CDC37_N PF03234.9 KPI39890.1 - 2.8e-58 197.1 5.3 2.8e-58 197.1 3.7 3.1 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KPI39890.1 - 7.6e-45 152.4 2.9 1.1e-44 152.0 1.1 2.1 1 1 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KPI39890.1 - 7.9e-26 89.8 2.2 7.9e-26 89.8 1.5 2.5 2 0 0 2 2 2 1 Cdc37 C terminal domain DUF1268 PF06896.6 KPI39890.1 - 0.038 14.3 0.2 0.038 14.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1268) MecA_N PF05223.6 KPI39890.1 - 0.059 13.4 4.1 0.15 12.1 0.2 3.0 3 0 0 3 3 3 0 NTF2-like N-terminal transpeptidase domain Bac_luciferase PF00296.15 KPI39891.1 - 1.4e-57 195.2 2.5 1.7e-57 194.8 1.7 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Med15 PF09606.5 KPI39892.1 - 2.6 6.1 18.5 2.3 6.3 12.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HeLo PF14479.1 KPI39893.1 - 2.5e-17 63.3 0.0 1.2e-15 57.8 0.0 2.5 1 1 0 1 1 1 1 Prion-inhibition and propagation Ribosomal_L7Ae PF01248.21 KPI39894.1 - 2.5e-23 81.4 0.0 3.6e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.13 KPI39894.1 - 1.8e-18 66.5 0.1 2.7e-18 66.0 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein L16p/L10e BUD22 PF09073.5 KPI39895.1 - 0.64 9.0 5.7 0.94 8.4 4.0 1.2 1 0 0 1 1 1 0 BUD22 Ldh_2 PF02615.9 KPI39896.1 - 1.1e-95 320.2 0.0 1.3e-95 320.0 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase MSC PF09402.5 KPI39897.1 - 1.5e-83 280.2 0.0 2.1e-83 279.8 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 KPI39897.1 - 7.5e-15 54.1 0.7 1.4e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 HeH/LEM domain DUF3534 PF12053.3 KPI39897.1 - 0.0091 15.8 0.2 0.071 12.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3534) adh_short PF00106.20 KPI39898.1 - 3.6e-31 108.3 0.5 4.9e-31 107.8 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI39898.1 - 2.2e-21 76.7 0.1 2.7e-21 76.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI39898.1 - 3.6e-10 39.7 0.4 6e-10 39.0 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI39898.1 - 0.0002 20.9 0.6 0.00033 20.1 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HHH_5 PF14520.1 KPI39898.1 - 0.066 13.3 0.3 3.8 7.7 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix domain NAD_binding_10 PF13460.1 KPI39899.1 - 4.2e-12 46.4 0.1 6.8e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KPI39899.1 - 0.0086 15.7 1.5 0.42 10.2 0.0 2.5 3 0 0 3 3 3 2 KR domain DNA_ligase_A_N PF04675.9 KPI39900.1 - 2.8e-51 173.8 0.3 5e-51 173.0 0.2 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KPI39900.1 - 1.4e-27 95.9 0.0 2.4e-26 91.9 0.0 2.6 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_M PF01068.16 KPI39900.1 - 6.9e-27 94.1 0.0 1.7e-14 53.6 0.0 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain DUF4661 PF15576.1 KPI39900.1 - 0.29 10.7 6.3 0.54 9.8 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) zf-HIT PF04438.11 KPI39901.1 - 9.9e-06 25.0 7.3 1.7e-05 24.3 5.0 1.4 1 0 0 1 1 1 1 HIT zinc finger Sugar_tr PF00083.19 KPI39902.1 - 4.2e-121 404.6 21.8 4.8e-121 404.4 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI39902.1 - 2.8e-24 85.5 34.1 1.2e-20 73.5 16.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI39902.1 - 8.6e-07 27.6 28.4 0.0011 17.4 4.5 3.4 3 1 0 3 3 3 3 MFS/sugar transport protein PAP2 PF01569.16 KPI39903.1 - 1.3e-23 83.1 1.7 1.3e-23 83.1 1.1 1.8 2 0 0 2 2 2 1 PAP2 superfamily LAT PF15234.1 KPI39903.1 - 0.00064 19.2 3.1 0.001 18.5 2.2 1.2 1 0 0 1 1 1 1 Linker for activation of T-cells Colicin_V PF02674.11 KPI39903.1 - 0.056 13.3 0.9 1.1 9.0 0.2 2.4 2 0 0 2 2 2 0 Colicin V production protein YhhN PF07947.9 KPI39903.1 - 0.16 11.3 0.1 0.16 11.3 0.1 2.2 2 1 0 2 2 2 0 YhhN-like protein Sugar_tr PF00083.19 KPI39904.1 - 1.2e-77 261.4 29.3 1.3e-77 261.3 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI39904.1 - 4.9e-25 87.9 28.1 6.9e-24 84.2 18.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KPI39904.1 - 0.34 9.0 15.8 0.043 12.0 4.3 2.7 1 1 2 3 3 3 0 Fungal trichothecene efflux pump (TRI12) MBOAT PF03062.14 KPI39905.1 - 5.1e-44 150.7 17.7 8.5e-44 149.9 12.3 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family TrbC PF04956.8 KPI39905.1 - 0.0017 18.3 0.3 0.0017 18.3 0.2 2.2 2 0 0 2 2 2 1 TrbC/VIRB2 family Prominin PF05478.6 KPI39907.1 - 0.00094 16.8 0.9 0.23 8.9 0.0 2.2 2 0 0 2 2 2 2 Prominin Apolipoprotein PF01442.13 KPI39907.1 - 0.0016 17.9 6.3 0.14 11.6 0.0 3.2 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain CP12 PF02672.10 KPI39907.1 - 0.026 15.0 0.8 11 6.5 0.2 3.5 2 1 1 3 3 3 0 CP12 domain Tape_meas_lam_C PF09718.5 KPI39907.1 - 0.054 13.4 2.4 1.3 9.0 0.1 4.0 5 1 0 5 5 5 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF883 PF05957.8 KPI39907.1 - 0.096 13.0 19.2 1.9 8.9 0.0 6.4 3 1 4 7 7 7 0 Bacterial protein of unknown function (DUF883) ApoC-I PF04691.7 KPI39907.1 - 0.099 12.3 0.3 0.099 12.3 0.2 3.3 3 1 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Peptidase_C39_2 PF13529.1 KPI39907.1 - 0.12 12.6 0.9 2.3 8.5 0.0 2.8 2 1 1 3 3 3 0 Peptidase_C39 like family DnaI_N PF07319.6 KPI39907.1 - 0.16 12.2 0.2 0.16 12.2 0.2 2.6 2 1 0 2 2 2 0 Primosomal protein DnaI N-terminus GlutR_dimer PF00745.15 KPI39907.1 - 0.48 10.3 7.4 0.075 12.9 0.4 2.9 4 0 0 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain Carbpep_Y_N PF05388.6 KPI39907.1 - 0.89 9.7 6.0 2.5 8.2 0.1 3.7 3 2 0 3 3 3 0 Carboxypeptidase Y pro-peptide Glyoxalase PF00903.20 KPI39908.1 - 1.1e-36 125.6 0.1 1.4e-17 63.8 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KPI39908.1 - 4.1e-30 104.5 0.0 1e-13 51.8 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KPI39908.1 - 9e-17 61.0 0.0 2.3e-06 27.5 0.0 3.7 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KPI39908.1 - 1.3e-08 34.9 0.0 0.00089 19.2 0.0 3.0 1 1 1 2 2 2 2 Glyoxalase-like domain Aldedh PF00171.17 KPI39909.1 - 1.1e-83 281.0 0.0 1.4e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-UBR PF02207.15 KPI39910.1 - 1.5e-18 66.2 10.4 3.8e-18 64.9 7.2 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 KPI39910.1 - 7.2e-05 22.4 0.4 0.00023 20.8 0.3 1.9 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 KPI39910.1 - 0.0036 17.0 2.5 0.0036 17.0 1.7 3.9 3 1 0 3 3 3 1 Ring finger domain Acetyltransf_11 PF13720.1 KPI39910.1 - 0.077 13.2 0.1 0.81 9.9 0.0 2.5 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DNA_pol_E_B PF04042.11 KPI39911.1 - 1.8e-47 161.2 0.0 2.7e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B APH PF01636.18 KPI39912.1 - 0.00071 19.3 0.0 0.21 11.2 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family p450 PF00067.17 KPI39914.1 - 3.1e-59 200.7 0.0 4.5e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF946 PF06101.6 KPI39916.1 - 6.2e-12 44.3 1.8 6.2e-12 44.2 0.3 1.7 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) Amino_oxidase PF01593.19 KPI39917.1 - 6.4e-18 65.0 0.0 1.1e-16 61.0 0.0 2.4 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KPI39917.1 - 3.8e-14 52.4 0.3 1.3e-13 50.7 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI39917.1 - 2e-07 30.2 0.1 6.1e-07 28.6 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KPI39917.1 - 0.001 18.8 0.0 0.13 11.9 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KPI39917.1 - 0.012 14.7 0.2 0.027 13.5 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI39917.1 - 0.028 13.2 0.1 0.13 11.0 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KPI39917.1 - 0.041 12.9 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KPI39917.1 - 0.059 13.4 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI39917.1 - 0.076 13.4 0.2 0.2 12.0 0.0 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI39917.1 - 0.14 11.9 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 KPI39917.1 - 0.27 10.9 0.5 0.97 9.1 0.1 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ECH PF00378.15 KPI39918.1 - 3.6e-23 81.9 0.0 4.7e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DICT PF10069.4 KPI39918.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Sensory domain found in DIguanylate Cyclases & Two-component systems MFS_1 PF07690.11 KPI39922.1 - 7.4e-19 67.6 57.6 2.4e-11 42.9 13.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Asparaginase_2 PF01112.13 KPI39924.1 - 3e-44 151.0 0.0 7.9e-22 77.3 0.0 3.1 2 1 1 3 3 3 3 Asparaginase PHY PF00360.15 KPI39925.1 - 5.8e-29 100.5 0.0 3.7e-28 97.9 0.0 2.2 2 0 0 2 2 2 1 Phytochrome region HATPase_c PF02518.21 KPI39925.1 - 8.8e-19 67.2 0.1 2.4e-18 65.8 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KPI39925.1 - 2.4e-12 46.6 1.8 2.9e-12 46.4 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 KPI39925.1 - 6.4e-12 45.8 0.0 2.6e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 GAF domain Response_reg PF00072.19 KPI39925.1 - 3.4e-11 43.1 0.0 1.4e-10 41.1 0.0 2.2 2 1 0 2 2 2 1 Response regulator receiver domain PAS_2 PF08446.6 KPI39925.1 - 3.2e-08 33.9 0.0 1.2e-07 32.2 0.0 2.0 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.1 KPI39925.1 - 0.022 14.4 0.1 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KPI39925.1 - 0.042 13.6 0.7 0.2 11.4 0.0 2.5 3 0 0 3 3 3 0 Histidine kinase-like ATPase domain Sec7 PF01369.15 KPI39926.1 - 3.5e-38 131.1 0.0 6.2e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 KPI39926.1 - 0.00055 20.1 0.1 0.0014 18.8 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 KPI39926.1 - 0.0018 18.4 0.2 0.0038 17.3 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain TPR_2 PF07719.12 KPI39927.1 - 1.3e-25 87.1 12.6 1.9e-05 24.2 0.0 9.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.23 KPI39927.1 - 1.6e-25 87.6 1.6 1.7e-05 24.2 0.0 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 KPI39927.1 - 2.6e-24 84.6 15.8 7.2e-06 25.5 0.0 7.4 5 2 2 8 8 8 6 TPR repeat Apc3 PF12895.2 KPI39927.1 - 1.7e-21 76.1 7.6 7.5e-17 61.2 0.2 4.5 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KPI39927.1 - 3e-15 55.9 8.6 0.0031 17.3 0.0 6.4 3 3 1 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 KPI39927.1 - 3.9e-14 52.8 13.8 2.5e-05 24.8 0.1 7.7 6 2 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 KPI39927.1 - 1.9e-12 46.6 12.2 0.15 12.7 0.1 8.2 6 2 4 10 10 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 KPI39927.1 - 2.8e-11 42.6 1.0 0.11 12.7 0.0 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 KPI39927.1 - 3.6e-09 35.7 0.0 0.23 11.3 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KPI39927.1 - 4.8e-09 36.4 9.7 0.035 14.4 0.0 6.2 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 KPI39927.1 - 1e-07 31.8 3.5 0.25 11.8 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 KPI39927.1 - 1.8e-07 30.9 5.1 0.0033 17.2 0.1 5.4 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KPI39927.1 - 2.5e-06 26.8 3.3 0.72 9.7 0.0 5.9 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 KPI39927.1 - 4e-05 22.8 1.4 0.11 11.5 0.0 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.3 KPI39927.1 - 0.029 13.1 0.1 1.2 7.8 0.1 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 MBOAT_2 PF13813.1 KPI39928.1 - 1.3e-15 57.2 0.7 1.3e-15 57.2 0.5 2.5 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family p450 PF00067.17 KPI39929.1 - 4.3e-07 28.8 0.0 4.3e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Xpo1 PF08389.7 KPI39929.1 - 0.0064 16.4 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 Exportin 1-like protein KH_1 PF00013.24 KPI39930.1 - 3.4e-39 132.2 2.6 4.3e-16 58.3 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KPI39930.1 - 2e-29 100.6 10.2 2e-11 43.2 1.3 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KPI39930.1 - 3.5e-11 42.4 1.8 0.013 15.0 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KPI39930.1 - 0.00081 19.1 6.0 1 9.1 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain KH_4 PF13083.1 KPI39930.1 - 0.0035 16.9 0.9 2.5 7.8 0.1 3.2 3 0 0 3 3 3 2 KH domain Esterase_phd PF10503.4 KPI39932.1 - 2e-08 33.7 0.3 0.0037 16.5 0.1 2.5 2 1 0 2 2 2 2 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KPI39932.1 - 0.00011 21.4 0.0 0.00032 19.9 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Rep_fac-A_C PF08646.5 KPI39933.1 - 1.5e-55 186.9 10.2 5.8e-54 181.7 3.4 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KPI39933.1 - 1.8e-21 75.8 0.2 8.2e-21 73.6 0.0 2.1 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KPI39933.1 - 5e-16 58.3 0.2 1.1e-10 41.1 0.0 4.0 4 1 0 4 4 4 2 OB-fold nucleic acid binding domain DUF223 PF02721.9 KPI39933.1 - 0.0064 16.5 0.0 0.027 14.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF223 Fe-ADH PF00465.14 KPI39934.1 - 3.6e-103 345.0 0.0 4.4e-103 344.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KPI39934.1 - 1.2e-15 57.4 0.0 6.2e-13 48.6 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 KPI39934.1 - 0.00069 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein ARID PF01388.16 KPI39935.1 - 1e-14 54.0 0.0 2.9e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Band_7 PF01145.20 KPI39936.1 - 1.1e-21 77.4 1.6 1.6e-21 77.0 1.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family F-box-like PF12937.2 KPI39937.1 - 0.059 13.1 0.0 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 F-box-like MFS_1 PF07690.11 KPI39938.1 - 0.0002 20.1 3.0 0.00038 19.2 2.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2628 PF10947.3 KPI39938.1 - 0.042 13.6 0.1 0.042 13.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) Claudin_2 PF13903.1 KPI39938.1 - 0.12 12.0 4.5 0.26 10.9 0.0 2.3 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4516 PF14990.1 KPI39938.1 - 0.17 11.4 3.3 2.4 7.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4516) Methyltransf_23 PF13489.1 KPI39939.1 - 1.2e-20 73.8 0.0 2.4e-20 72.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI39939.1 - 1.1e-12 48.4 0.0 1.1e-11 45.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI39939.1 - 1.7e-08 34.2 0.0 1.2e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI39939.1 - 1.1e-06 29.0 0.0 3e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI39939.1 - 3.5e-06 27.4 0.0 1.8e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI39939.1 - 5.3e-05 23.2 0.1 0.0009 19.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KPI39939.1 - 5.3e-05 23.2 0.0 8.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 KPI39939.1 - 8.6e-05 21.6 0.0 0.00022 20.3 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 KPI39939.1 - 0.00037 20.8 0.0 0.0011 19.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KPI39939.1 - 0.00081 18.8 0.0 0.0081 15.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain DUF938 PF06080.7 KPI39939.1 - 0.018 14.6 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Ubie_methyltran PF01209.13 KPI39939.1 - 0.088 11.9 0.0 0.21 10.6 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 KPI39939.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_16 PF10294.4 KPI39939.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 KPI39939.1 - 0.18 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Patatin PF01734.17 KPI39940.1 - 1.7e-22 80.3 0.7 1.7e-22 80.3 0.5 2.7 3 0 0 3 3 3 1 Patatin-like phospholipase Dynamin_N PF00350.18 KPI39940.1 - 0.0061 16.3 0.9 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KPI39940.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-C3HC4_2 PF13923.1 KPI39940.1 - 1.8 8.6 19.2 0.29 11.1 2.5 3.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KPI39940.1 - 6.6 6.5 19.5 1.9 8.2 2.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.20 KPI39943.1 - 7.3e-18 65.0 0.1 1.6e-17 63.9 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI39943.1 - 1.1e-08 34.9 0.4 2.2e-08 33.9 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KPI39943.1 - 6e-06 25.8 0.0 7.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI39943.1 - 6.5e-06 26.2 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KPI39943.1 - 1.9e-05 24.5 0.1 2.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 KPI39943.1 - 0.012 15.6 0.2 0.018 15.1 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.21 KPI39943.1 - 0.018 14.5 0.3 0.032 13.7 0.2 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 KPI39943.1 - 0.041 13.7 0.2 0.062 13.1 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 KPI39943.1 - 0.078 12.9 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 KPI39943.1 - 0.089 13.2 0.3 0.2 12.0 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 KPI39943.1 - 0.13 11.4 0.3 0.19 10.9 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family HET PF06985.6 KPI39944.1 - 4.3e-20 72.2 0.5 1.4e-15 57.6 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_trans_2_3 PF13632.1 KPI39944.1 - 0.014 15.1 0.5 0.057 13.1 0.3 2.0 2 0 0 2 2 2 0 Glycosyl transferase family group 2 CobA_CobO_BtuR PF02572.10 KPI39944.1 - 0.18 11.3 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Surfac_D-trimer PF09006.6 KPI39945.1 - 0.17 11.6 3.8 0.18 11.5 0.9 2.3 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation zf-C3HC PF07967.8 KPI39946.1 - 1.4e-31 108.9 5.9 1.5e-27 96.0 0.0 3.1 3 1 0 3 3 3 2 C3HC zinc finger-like Rsm1 PF08600.5 KPI39946.1 - 3.3e-18 65.3 3.3 2.1e-16 59.5 0.1 2.9 3 0 0 3 3 3 2 Rsm1-like BIR PF00653.16 KPI39946.1 - 0.0008 19.7 1.3 0.75 10.2 0.0 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain WD40 PF00400.27 KPI39947.1 - 2.7e-05 23.8 0.3 0.27 11.1 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat CFEM PF05730.6 KPI39948.1 - 1.8e-13 50.1 7.2 4.2e-13 48.9 5.0 1.7 1 0 0 1 1 1 1 CFEM domain LRR_4 PF12799.2 KPI39949.1 - 5e-50 166.4 67.4 1.3e-07 31.1 0.2 12.5 6 3 4 12 12 12 10 Leucine Rich repeats (2 copies) PP2C PF00481.16 KPI39949.1 - 4e-46 157.4 0.0 9.1e-46 156.3 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 KPI39949.1 - 3.6e-41 138.7 61.4 5.5e-12 45.2 1.2 11.6 4 2 11 16 16 16 12 Leucine rich repeat Guanylate_cyc PF00211.15 KPI39949.1 - 8.5e-26 90.4 0.0 1.9e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 KPI39949.1 - 7.9e-21 70.8 60.7 0.018 15.0 0.1 18.6 17 3 1 18 18 18 7 Leucine Rich Repeat LRR_7 PF13504.1 KPI39949.1 - 7.2e-12 43.4 51.7 0.062 13.5 0.1 16.2 17 0 0 17 17 17 2 Leucine rich repeat RA PF00788.18 KPI39949.1 - 2.9e-10 40.4 0.0 8.7e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ad_cyc_g-alpha PF08509.6 KPI39949.1 - 2.4e-06 26.7 0.3 8.5e-06 25.0 0.2 2.0 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_6 PF13516.1 KPI39949.1 - 3.6e-06 26.4 57.2 5.1 7.4 0.0 16.2 16 1 1 17 17 17 3 Leucine Rich repeat LRR_9 PF14580.1 KPI39949.1 - 0.00072 19.1 8.7 1.3 8.5 0.0 4.6 2 1 2 5 5 5 2 Leucine-rich repeat Aminotran_1_2 PF00155.16 KPI39950.1 - 5.2e-38 130.9 0.0 7e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Zn_clus PF00172.13 KPI39951.1 - 1.3e-07 31.4 9.7 2e-07 30.7 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_2 PF07883.6 KPI39952.1 - 1.4e-07 30.9 0.0 2.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KPI39952.1 - 0.0021 17.4 0.0 0.009 15.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AA_permease_2 PF13520.1 KPI39953.1 - 1.8e-53 181.6 48.7 2.1e-53 181.4 33.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI39953.1 - 5.9e-15 54.5 41.3 9.7e-15 53.8 28.6 1.3 1 1 0 1 1 1 1 Amino acid permease DUF4234 PF14018.1 KPI39953.1 - 0.0033 17.1 0.2 0.0033 17.1 0.1 3.7 6 0 0 6 6 6 1 Domain of unknown function (DUF4234) DUF1356 PF07092.7 KPI39953.1 - 1.1 8.4 4.0 0.49 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) MFS_1 PF07690.11 KPI39954.1 - 1.7e-39 135.5 41.0 1.7e-39 135.5 28.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily POC1 PF10450.4 KPI39955.1 - 0.13 10.9 0.6 0.24 10.1 0.4 1.3 1 0 0 1 1 1 0 POC1 chaperone Myosin_tail_1 PF01576.14 KPI39955.1 - 6.9 4.2 104.1 25 2.3 72.2 1.8 1 1 0 1 1 1 0 Myosin tail Autophagy_N PF03986.8 KPI39956.1 - 9.1e-45 151.9 0.4 1.8e-44 151.0 0.0 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KPI39956.1 - 6.2e-22 77.5 0.3 1.2e-21 76.6 0.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KPI39956.1 - 1.6e-14 52.7 0.4 2.6e-14 51.9 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Alpha-amylase PF00128.19 KPI39957.1 - 8.7e-94 314.4 0.1 1.2e-93 313.9 0.1 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KPI39957.1 - 0.00012 21.1 0.0 0.00019 20.4 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme F-box PF00646.28 KPI39958.1 - 0.017 14.8 0.6 0.054 13.1 0.4 1.9 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 KPI39958.1 - 0.071 12.8 0.5 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 F-box-like Lectin_leg-like PF03388.8 KPI39959.1 - 4.3e-25 88.1 0.0 6.1e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Baculo_PEP_C PF04513.7 KPI39959.1 - 0.018 14.8 1.2 0.052 13.3 0.8 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Uds1 PF15456.1 KPI39959.1 - 0.033 14.1 0.1 0.064 13.2 0.0 1.5 1 1 0 1 1 1 0 Up-regulated During Septation FliD_C PF07195.7 KPI39959.1 - 0.061 12.6 0.3 0.13 11.5 0.2 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF2730 PF10805.3 KPI39959.1 - 0.1 12.3 0.1 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) CCDC32 PF14989.1 KPI39959.1 - 0.14 11.9 0.6 1.1 9.0 0.1 2.1 1 1 1 2 2 2 0 Coiled-coil domain containing 32 FlgN PF05130.7 KPI39959.1 - 0.15 12.3 0.5 0.23 11.6 0.3 1.2 1 0 0 1 1 1 0 FlgN protein DUF4140 PF13600.1 KPI39959.1 - 0.16 12.4 0.3 2.4 8.6 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HalX PF08663.5 KPI39959.1 - 0.2 11.6 0.6 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 HalX domain adh_short PF00106.20 KPI39960.1 - 9.2e-14 51.7 0.0 1.7e-13 50.8 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI39960.1 - 2.9e-06 27.0 0.0 1.8e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KPI39960.1 - 0.0085 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 KPI39960.1 - 0.041 13.9 0.0 0.12 12.4 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KPI39960.1 - 0.083 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KPI39960.1 - 0.1 12.4 0.2 0.83 9.4 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PPR_3 PF13812.1 KPI39961.1 - 1.6e-07 31.0 9.5 0.11 12.8 0.1 7.8 7 1 0 8 8 8 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 KPI39961.1 - 2.5e-06 27.3 6.7 4.8 7.2 0.0 7.0 7 1 1 8 8 8 3 PPR repeat family PPR_1 PF12854.2 KPI39961.1 - 0.016 14.6 0.2 0.91 9.0 0.0 3.3 2 0 0 2 2 2 0 PPR repeat PPR PF01535.15 KPI39961.1 - 1.5 9.0 0.0 1.5 9.0 0.0 6.0 8 0 0 8 8 8 0 PPR repeat TPR_19 PF14559.1 KPI39961.1 - 1.8 8.9 8.1 4.8 7.5 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.11 KPI39962.1 - 2.5e-44 151.4 65.4 2.1e-43 148.3 44.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Tropomyosin_1 PF12718.2 KPI39964.1 - 0.0026 17.5 12.5 0.0026 17.5 8.6 7.4 1 1 3 6 6 6 1 Tropomyosin like GAS PF13851.1 KPI39964.1 - 0.0052 16.0 92.4 0.013 14.7 7.0 7.6 1 1 5 7 7 7 5 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 KPI39964.1 - 0.78 9.6 104.6 0.02 14.7 9.6 7.6 2 2 5 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 tRNA-synt_2 PF00152.15 KPI39965.1 - 1.1e-89 300.4 0.2 1.6e-89 300.0 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KPI39965.1 - 2.3e-12 46.6 0.0 3.9e-11 42.6 0.0 2.5 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KPI39965.1 - 8.1e-06 25.2 0.3 0.044 12.9 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KPI39965.1 - 0.00086 18.9 0.0 0.17 11.4 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Zn_clus PF00172.13 KPI39966.1 - 2.3e-05 24.1 6.7 4.9e-05 23.1 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_5 PF13857.1 KPI39966.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Amidohydro_1 PF01979.15 KPI39967.1 - 2.1e-11 44.0 0.0 2.9e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KPI39967.1 - 1.8e-07 31.4 0.2 3.3e-07 30.6 0.0 1.4 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KPI39967.1 - 7.7e-07 28.6 0.0 1.1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Ldh_1_N PF00056.18 KPI39967.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF1652 PF07865.6 KPI39967.1 - 0.13 11.8 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) KIP1 PF07765.7 KPI39967.1 - 0.14 12.0 0.1 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 KIP1-like protein AMP-binding PF00501.23 KPI39968.1 - 1.8e-57 194.6 0.0 2.3e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI39968.1 - 1.1e-12 48.6 0.1 8.6e-12 45.8 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACOX PF01756.14 KPI39969.1 - 1e-33 116.3 0.0 2.4e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KPI39969.1 - 5.4e-23 81.6 0.9 5.4e-23 81.6 0.6 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KPI39969.1 - 9.6e-09 34.6 0.1 2.7e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KPI39969.1 - 0.041 14.4 0.0 0.14 12.6 0.0 2.0 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain RB_A PF01858.12 KPI39970.1 - 0.041 13.5 0.1 0.077 12.6 0.1 1.4 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain SICA_beta PF12878.2 KPI39970.1 - 0.072 12.8 0.2 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 SICA extracellular beta domain ADH_zinc_N PF00107.21 KPI39971.1 - 7.9e-28 96.5 0.5 1.4e-27 95.8 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI39971.1 - 1.4e-17 64.7 0.1 3.1e-17 63.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI39971.1 - 6.3e-11 42.0 0.0 1.6e-08 34.2 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KPI39971.1 - 0.0019 18.1 0.0 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 KPI39971.1 - 0.037 13.5 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ERM PF00769.14 KPI39973.1 - 0.068 12.6 0.0 0.14 11.7 0.0 1.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family PLRV_ORF5 PF01690.12 KPI39973.1 - 1.6 7.7 13.1 3 6.8 9.1 1.4 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF788 PF05620.6 KPI39974.1 - 6.5e-44 149.7 0.0 7.4e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) DRIM PF07539.7 KPI39975.1 - 4.9e-29 100.5 0.5 1.7e-28 98.8 0.0 2.3 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.17 KPI39975.1 - 0.00024 20.9 8.8 6.3 7.1 0.0 8.8 9 0 0 9 9 9 2 HEAT repeat WD40 PF00400.27 KPI39976.1 - 0.024 14.5 0.1 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat AAA_16 PF13191.1 KPI39977.1 - 0.0015 18.5 0.0 0.0043 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 KPI39977.1 - 0.066 12.2 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Zn_clus PF00172.13 KPI39978.1 - 1.2e-08 34.6 9.4 1.7e-08 34.1 6.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3328 PF11807.3 KPI39981.1 - 5.7e-49 166.7 0.1 1.2e-48 165.6 0.1 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) Fungal_trans_2 PF11951.3 KPI39982.1 - 3.7e-24 85.0 1.2 4.5e-24 84.7 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain FtsJ PF01728.14 KPI39983.1 - 1.3e-63 214.2 0.0 1.8e-63 213.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase ketoacyl-synt PF00109.21 KPI39984.1 - 5.5e-52 176.7 4.6 1.4e-51 175.4 0.9 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KPI39984.1 - 3.5e-34 117.2 1.0 7.1e-34 116.2 0.7 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KPI39984.1 - 2.1e-06 26.8 0.1 4.9e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KPI39984.1 - 0.00032 20.1 4.2 0.012 15.0 0.4 3.0 2 2 1 3 3 3 2 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KPI39984.1 - 0.0073 15.9 0.4 4.6 6.9 0.0 3.1 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Lactamase_B_3 PF13483.1 KPI39985.1 - 4.8e-08 32.8 0.0 1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Tim54 PF11711.3 KPI39985.1 - 0.16 10.5 0.0 0.32 9.5 0.0 1.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CSTF2_hinge PF14327.1 KPI39987.1 - 4e-26 90.9 6.0 4e-26 90.9 4.2 2.5 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KPI39987.1 - 4.5e-22 77.4 0.1 6.8e-22 76.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI39987.1 - 3.7e-17 62.0 0.0 1.1e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 KPI39987.1 - 1.2e-08 34.0 7.2 2.7e-08 32.9 5.0 1.6 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 KPI39987.1 - 5.5e-08 32.5 0.0 8.2e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2360 PF10152.4 KPI39987.1 - 0.9 9.8 12.9 0.14 12.4 5.2 2.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) PseudoU_synth_1 PF01416.15 KPI39988.1 - 3.7e-21 75.5 0.0 2.1e-09 37.7 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase MFS_1 PF07690.11 KPI39989.1 - 1.4e-34 119.3 27.7 2e-34 118.8 19.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PIRT PF15099.1 KPI39989.1 - 0.017 14.3 0.1 0.044 12.9 0.0 1.7 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family MFS_1_like PF12832.2 KPI39989.1 - 0.051 13.3 2.2 0.19 11.5 0.1 2.5 2 0 0 2 2 2 0 MFS_1 like family adh_short PF00106.20 KPI39991.1 - 4.4e-20 72.2 0.0 6.4e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI39991.1 - 3.2e-09 36.9 0.0 4.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI39991.1 - 2.7e-07 30.4 0.0 7.3e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI39991.1 - 0.00027 21.0 0.0 0.00043 20.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 KPI39991.1 - 0.036 13.7 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.5 KPI39991.1 - 0.089 11.9 0.0 0.22 10.6 0.0 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 KPI39991.1 - 0.094 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GST_N_3 PF13417.1 KPI39992.1 - 9.5e-06 25.7 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI39992.1 - 3.8e-05 23.6 0.0 8.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KPI39992.1 - 0.0082 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tachylectin PF14517.1 KPI39992.1 - 0.087 12.1 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Tachylectin GST_C PF00043.20 KPI39992.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SIS PF01380.17 KPI39993.1 - 3.9e-14 52.3 0.2 1.3e-13 50.6 0.2 1.9 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 KPI39993.1 - 0.015 15.0 0.1 0.68 9.6 0.1 2.2 1 1 0 1 1 1 0 SIS domain WGG PF10273.4 KPI39994.1 - 4.4e-20 71.5 0.1 7.1e-20 70.8 0.1 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 KPI39994.1 - 0.055 13.4 0.3 0.055 13.4 0.2 1.8 1 1 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) MFS_1 PF07690.11 KPI39995.1 - 9.1e-16 57.5 44.4 9.1e-16 57.5 30.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI39995.1 - 2.1e-07 29.8 12.8 2.1e-07 29.8 8.9 2.6 1 1 0 2 2 2 1 Sugar (and other) transporter Pox_MCEL PF03291.11 KPI39996.1 - 1.7e-52 178.3 0.0 2.7e-37 128.3 0.0 3.2 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 KPI39996.1 - 2.1e-08 34.5 0.0 5.8e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI39996.1 - 4.5e-07 30.4 0.0 1.3e-06 28.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI39996.1 - 7.8e-07 29.5 0.0 5.1e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI39996.1 - 9.9e-07 28.6 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI39996.1 - 6e-06 26.5 0.0 2.1e-05 24.8 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI39996.1 - 2e-05 24.2 0.0 0.0021 17.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain DDRGK PF09756.4 KPI39996.1 - 0.0022 17.4 0.1 0.94 8.8 0.0 2.7 3 0 0 3 3 3 2 DDRGK domain THRAP3_BCLAF1 PF15440.1 KPI39996.1 - 0.0084 14.8 15.0 0.015 13.9 10.4 1.6 1 0 0 1 1 1 1 THRAP3/BCLAF1 family Methyltransf_4 PF02390.12 KPI39996.1 - 0.039 12.9 0.0 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase NNMT_PNMT_TEMT PF01234.12 KPI39996.1 - 0.062 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Dopey_N PF04118.9 KPI39998.1 - 2.9e-105 351.4 0.0 1.6e-104 349.0 0.0 2.1 2 0 0 2 2 2 1 Dopey, N-terminal D-ser_dehydrat PF14031.1 KPI39999.1 - 5.3e-24 84.2 0.0 1e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KPI39999.1 - 2.6e-13 50.0 0.0 4.4e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF3446 PF11928.3 KPI40000.1 - 0.071 13.3 3.4 0.35 11.0 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) AChE_tetra PF08674.5 KPI40001.1 - 0.11 12.0 0.2 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain Beta-lactamase PF00144.19 KPI40002.1 - 9.4e-32 110.3 0.0 1.5e-31 109.6 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase Fungal_trans_2 PF11951.3 KPI40004.1 - 2.8e-28 98.5 2.5 4.5e-28 97.9 1.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N_2 PF13602.1 KPI40005.1 - 4e-20 72.9 0.0 7e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KPI40005.1 - 3.2e-10 39.6 0.0 9.3e-10 38.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI40005.1 - 0.001 18.7 0.2 0.93 9.2 0.0 3.5 1 1 2 3 3 3 1 Alcohol dehydrogenase GroES-like domain UCR_UQCRX_QCR9 PF05365.7 KPI40006.1 - 1.1e-26 92.2 2.1 1.2e-26 92.0 1.5 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Glyco_hydro_20 PF00728.17 KPI40007.1 - 5.3e-52 177.1 0.0 1.7e-50 172.1 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KPI40007.1 - 8.8e-14 52.2 0.0 1.9e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KPI40007.1 - 0.0021 18.5 0.0 0.004 17.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 V-set_CD47 PF08204.6 KPI40007.1 - 0.023 14.4 0.4 0.76 9.5 0.1 2.3 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain HA2 PF04408.18 KPI40008.1 - 2e-16 59.8 0.0 4.3e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KPI40008.1 - 6.6e-16 58.1 0.0 1.4e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KPI40008.1 - 9.1e-11 41.4 0.0 6.1e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KPI40008.1 - 4.3e-05 23.0 0.0 9.1e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KPI40008.1 - 0.0012 18.9 0.0 0.0044 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KPI40008.1 - 0.0015 17.5 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 KPI40008.1 - 0.0057 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KPI40008.1 - 0.043 13.2 0.0 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family KaiC PF06745.8 KPI40008.1 - 0.053 12.6 0.0 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 KaiC G-alpha PF00503.15 KPI40008.1 - 0.06 12.0 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.1 KPI40008.1 - 0.06 13.3 0.0 0.26 11.2 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain Herpes_capsid PF06112.6 KPI40008.1 - 0.23 11.5 6.9 0.86 9.6 4.8 2.0 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Pol_alpha_B_N PF08418.5 KPI40008.1 - 2.8 7.4 8.3 0.13 11.7 1.7 1.7 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Annexin PF00191.15 KPI40009.1 - 9.2e-46 153.6 1.4 6.6e-13 48.3 0.0 4.1 4 0 0 4 4 4 4 Annexin Pro-rich PF15240.1 KPI40010.1 - 0.0082 16.2 16.1 0.011 15.8 11.2 1.2 1 0 0 1 1 1 1 Proline-rich DUF605 PF04652.11 KPI40010.1 - 0.31 10.4 21.3 0.38 10.1 14.7 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KPI40010.1 - 0.9 7.6 12.5 1 7.5 8.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PAP1 PF08601.5 KPI40010.1 - 6.3 6.3 15.4 8 6.0 10.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Presenilin PF01080.12 KPI40010.1 - 7.1 5.3 9.9 8.5 5.0 6.9 1.1 1 0 0 1 1 1 0 Presenilin DUF4551 PF15087.1 KPI40010.1 - 10 4.3 8.7 11 4.2 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF946 PF06101.6 KPI40011.1 - 4.5e-13 48.0 0.2 1.4e-12 46.4 0.2 1.7 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) QRPTase_C PF01729.14 KPI40011.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain MFS_1 PF07690.11 KPI40012.1 - 5.5e-35 120.7 25.6 6.4e-35 120.5 17.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Col_cuticle_N PF01484.12 KPI40012.1 - 0.064 12.9 0.3 0.23 11.1 0.2 2.0 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain WAC_Acf1_DNA_bd PF10537.4 KPI40013.1 - 1.6e-38 130.9 0.1 1.3e-37 128.0 0.0 2.6 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 KPI40013.1 - 3.2e-18 65.2 2.9 5.8e-18 64.4 2.0 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 KPI40013.1 - 1.8e-09 37.1 0.2 3.9e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 KPI40013.1 - 0.00028 20.6 0.7 0.00088 19.0 0.5 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 SNO PF01174.14 KPI40014.1 - 3e-57 193.2 0.0 6.4e-46 156.3 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KPI40014.1 - 1.6e-10 40.7 0.0 4.7e-08 32.7 0.0 2.3 2 1 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 KPI40014.1 - 2.8e-05 23.6 0.0 9.3e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DUF4066 PF13278.1 KPI40014.1 - 4.8e-05 22.6 0.1 8.6e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KPI40014.1 - 7e-05 22.3 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Cellulase PF00150.13 KPI40015.1 - 1.7e-06 27.4 0.2 4e-06 26.2 0.1 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TPPK_C PF12555.3 KPI40015.1 - 0.1 12.3 1.7 0.23 11.2 1.2 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Serglycin PF04360.7 KPI40015.1 - 0.11 12.2 0.6 0.26 10.9 0.1 1.9 2 0 0 2 2 2 0 Serglycin adh_short PF00106.20 KPI40016.1 - 8.7e-12 45.2 0.0 1.4e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI40016.1 - 9.2e-08 31.9 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF3530 PF12048.3 KPI40016.1 - 0.053 12.5 0.4 0.098 11.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Epimerase PF01370.16 KPI40016.1 - 0.057 12.8 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF883 PF05957.8 KPI40017.1 - 0.026 14.9 0.7 0.031 14.6 0.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) TruB_N PF01509.13 KPI40017.1 - 0.049 13.7 0.4 0.051 13.7 0.3 1.2 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) RRF PF01765.14 KPI40017.1 - 0.17 11.3 2.6 0.16 11.3 1.8 1.1 1 0 0 1 1 1 0 Ribosome recycling factor ADH_N PF08240.7 KPI40019.1 - 2.2e-22 78.8 2.5 3.6e-22 78.1 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI40019.1 - 9.8e-13 47.7 0.0 1.8e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KPI40019.1 - 0.00079 18.6 0.1 0.0014 17.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KPI40019.1 - 0.013 15.0 0.3 0.027 14.0 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 KPI40019.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Zn_clus PF00172.13 KPI40020.1 - 0.024 14.5 2.7 0.041 13.7 1.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Serglycin PF04360.7 KPI40020.1 - 0.54 9.9 39.1 0.14 11.9 1.0 4.3 3 1 1 4 4 4 0 Serglycin DUF21 PF01595.15 KPI40021.1 - 4.8e-33 113.9 0.0 6.9e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KPI40021.1 - 5.2e-08 32.5 0.6 0.0053 16.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain COesterase PF00135.23 KPI40022.1 - 1.6e-98 330.7 0.0 2e-98 330.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI40022.1 - 4.2e-05 23.2 0.2 0.00023 20.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Arginase PF00491.16 KPI40023.1 - 5.3e-92 308.0 0.1 6.4e-92 307.7 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KPI40023.1 - 0.04 14.1 0.5 0.065 13.4 0.4 1.3 1 0 0 1 1 1 0 UPF0489 domain JmjC PF02373.17 KPI40024.1 - 1.1e-09 38.5 0.1 3.2e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 KPI40024.1 - 2.1e-08 33.9 0.1 4.5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain PHD PF00628.24 KPI40024.1 - 4.6e-07 29.4 6.1 4.6e-07 29.4 4.2 2.6 3 0 0 3 3 3 1 PHD-finger DUF1423 PF07227.6 KPI40024.1 - 0.18 10.4 4.1 0.3 9.6 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) PHD_2 PF13831.1 KPI40024.1 - 0.2 10.9 2.4 0.67 9.3 1.7 1.9 1 0 0 1 1 1 0 PHD-finger Zn_clus PF00172.13 KPI40024.1 - 0.38 10.7 28.7 0.21 11.5 4.6 3.4 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3761 PF12587.3 KPI40024.1 - 3.4 7.8 8.6 2 8.5 0.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3761) Amino_oxidase PF01593.19 KPI40027.1 - 1.4e-31 110.1 0.5 3.4e-30 105.5 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KPI40027.1 - 0.0019 18.2 1.6 0.0052 16.7 0.7 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KPI40027.1 - 0.0024 17.0 0.2 0.0033 16.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KPI40027.1 - 0.014 14.4 0.2 0.023 13.7 0.2 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KPI40027.1 - 0.041 13.9 0.1 0.56 10.2 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI40027.1 - 0.052 12.3 1.6 0.091 11.5 1.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KPI40027.1 - 0.056 13.3 0.3 0.089 12.6 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI40027.1 - 0.079 11.8 0.4 0.11 11.3 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.19 KPI40027.1 - 0.1 11.4 3.4 0.21 10.4 1.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase PXA PF02194.10 KPI40028.1 - 3.4e-37 127.7 2.1 3.6e-37 127.7 0.0 2.1 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 KPI40028.1 - 5.6e-18 65.0 2.4 3.2e-17 62.6 0.0 3.0 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 KPI40028.1 - 3e-05 23.7 0.0 8.3e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 PX domain CwfJ_C_2 PF04676.9 KPI40029.1 - 2.4e-18 66.4 0.4 4.9e-18 65.4 0.3 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 KPI40029.1 - 2.1e-17 62.9 0.0 3.6e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF2433 PF10360.4 KPI40030.1 - 2e-39 134.8 0.0 3.8e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 KPI40030.1 - 0.01 15.6 0.0 0.024 14.4 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KPI40030.1 - 0.017 14.5 0.1 0.038 13.3 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase RPN7 PF10602.4 KPI40032.1 - 1.8e-57 193.5 0.3 3.1e-57 192.8 0.2 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KPI40032.1 - 2e-17 63.4 0.0 4.2e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 KPI40032.1 - 0.013 15.2 0.0 0.078 12.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.17 KPI40033.1 - 1.7e-50 171.8 0.0 1.1e-49 169.3 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 L6_membrane PF05805.7 KPI40033.1 - 0.1 12.1 0.1 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 L6 membrane protein zf-CCCH_2 PF14608.1 KPI40034.1 - 1.1e-09 37.9 55.8 0.00029 20.7 7.5 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 KPI40034.1 - 0.00022 21.2 0.0 0.00039 20.4 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) BmKX PF09132.5 KPI40034.1 - 0.029 14.2 7.8 0.97 9.3 1.1 3.0 2 0 0 2 2 2 0 BmKX Med14 PF08638.6 KPI40035.1 - 1.9e-55 187.1 0.2 3.6e-55 186.2 0.2 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 WW PF00397.21 KPI40036.1 - 3.6e-11 42.7 6.8 3.6e-08 33.0 3.1 2.7 2 0 0 2 2 2 2 WW domain FF PF01846.14 KPI40036.1 - 7.4e-11 41.8 5.4 2.6e-07 30.4 0.0 3.7 3 0 0 3 3 3 2 FF domain AA_permease_2 PF13520.1 KPI40037.1 - 1.1e-44 152.7 47.1 1.3e-44 152.3 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease GST_N_3 PF13417.1 KPI40038.1 - 4.8e-10 39.5 0.0 7.8e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KPI40038.1 - 2.9e-08 33.7 0.0 6.5e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI40038.1 - 8.1e-06 25.7 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KPI40038.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MOSC_N PF03476.11 KPI40039.1 - 3.1e-21 75.2 0.0 5.2e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KPI40039.1 - 7.8e-18 64.2 0.3 2.2e-11 43.3 0.0 2.2 1 1 1 2 2 2 2 MOSC domain PARP_regulatory PF01358.13 KPI40039.1 - 0.095 11.3 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit MDH PF02315.11 KPI40041.1 - 0.021 14.7 0.9 0.053 13.4 0.6 1.7 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit Cupin_2 PF07883.6 KPI40042.1 - 5.6e-17 61.0 0.0 9.9e-17 60.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KPI40042.1 - 2.3e-06 27.3 0.0 3.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KPI40042.1 - 9.1e-06 25.1 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 KPI40042.1 - 8.8e-05 21.8 0.1 0.00018 20.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.9 KPI40042.1 - 0.00013 21.9 0.0 0.00023 21.1 0.0 1.5 1 1 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.2 KPI40042.1 - 0.0035 16.9 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Cupin GPI PF06560.6 KPI40042.1 - 0.0073 15.3 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) JmjC PF02373.17 KPI40042.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase EutQ PF06249.7 KPI40042.1 - 0.019 14.4 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Hemerythrin PF01814.18 KPI40043.1 - 0.0094 16.1 7.3 0.016 15.4 5.1 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain WLM PF08325.5 KPI40044.1 - 2.8e-51 174.0 0.6 1.1e-50 172.0 0.1 2.0 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.12 KPI40044.1 - 4e-09 36.5 0.3 8.2e-09 35.5 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 DUF605 PF04652.11 KPI40044.1 - 0.053 12.9 12.2 0.076 12.3 8.4 1.2 1 0 0 1 1 1 0 Vta1 like Zn_clus PF00172.13 KPI40045.1 - 1.8e-09 37.3 7.5 3.7e-09 36.3 5.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KPI40045.1 - 1.1e-07 31.0 0.0 1.9e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.21 KPI40046.1 - 5.6e-25 87.3 0.1 8.9e-25 86.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI40046.1 - 1.4e-19 71.2 0.0 2.3e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ABC_tran PF00005.22 KPI40048.1 - 8.6e-31 107.0 0.0 3.7e-30 105.0 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 KPI40048.1 - 5.7e-19 68.5 6.9 1.3e-18 67.4 4.8 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KPI40048.1 - 5e-05 22.6 0.1 0.0028 16.9 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KPI40048.1 - 8.2e-05 22.6 0.0 0.04 13.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KPI40048.1 - 0.002 17.6 2.7 0.014 14.8 0.0 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KPI40048.1 - 0.0027 18.5 0.0 0.0087 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KPI40048.1 - 0.0037 16.3 0.0 0.0069 15.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 KPI40048.1 - 0.0075 16.2 3.3 0.017 15.0 0.5 2.6 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KPI40048.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KPI40048.1 - 0.024 14.5 0.1 0.28 11.1 0.0 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KPI40048.1 - 0.027 14.6 0.3 0.23 11.5 0.2 2.4 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 KPI40048.1 - 0.038 12.9 0.0 0.078 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 KPI40048.1 - 0.061 12.8 0.7 0.74 9.3 0.0 2.4 2 1 1 3 3 3 0 AAA domain Dynamin_N PF00350.18 KPI40048.1 - 0.075 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Dynamin family AAA_18 PF13238.1 KPI40048.1 - 0.077 13.3 0.6 0.22 11.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KPI40048.1 - 0.083 12.6 0.2 0.17 11.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 KPI40048.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.4 KPI40048.1 - 0.11 11.0 0.0 0.18 10.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.1 KPI40048.1 - 0.13 12.5 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain FAA_hydrolase PF01557.13 KPI40049.1 - 2.3e-43 148.2 0.0 3.8e-43 147.4 0.0 1.3 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KPI40049.1 - 1.3e-20 73.3 0.0 2.2e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal PI3_PI4_kinase PF00454.22 KPI40052.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase DnaJ PF00226.26 KPI40053.1 - 3.1e-28 97.3 1.9 4.7e-28 96.7 1.3 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KPI40053.1 - 6.5e-24 83.6 1.4 4.6e-21 74.5 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DUF572 PF04502.8 KPI40054.1 - 4.8e-44 150.8 0.0 5.8e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) GFA PF04828.9 KPI40055.1 - 5.2e-18 64.7 0.9 8.6e-18 64.0 0.6 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF2568 PF10823.3 KPI40055.1 - 0.08 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2568) AA_permease_2 PF13520.1 KPI40056.1 - 7.3e-49 166.4 48.8 3.4e-27 95.0 21.5 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 KPI40056.1 - 3.4e-10 38.8 38.7 2.5e-05 22.8 6.7 2.2 1 1 1 2 2 2 2 Amino acid permease Complex1_30kDa PF00329.14 KPI40057.1 - 1.5e-35 121.5 0.0 2.1e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF4267 PF14087.1 KPI40058.1 - 5.6e-26 90.3 2.0 6.7e-26 90.0 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF872 PF05915.7 KPI40058.1 - 0.35 10.7 1.3 0.5 10.2 0.1 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF4131 PF13567.1 KPI40058.1 - 0.83 9.0 3.3 9.1 5.6 2.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF308 PF03729.8 KPI40058.1 - 4.6 7.3 14.6 8.3 6.4 4.1 2.8 1 1 1 3 3 3 0 Short repeat of unknown function (DUF308) KH_1 PF00013.24 KPI40059.1 - 7.9e-77 252.8 24.0 9.4e-14 50.8 0.2 10.8 10 1 0 10 10 10 8 KH domain KH_3 PF13014.1 KPI40059.1 - 1.5e-47 158.5 33.2 4.5e-09 35.7 0.1 10.6 11 0 0 11 11 11 7 KH domain KH_4 PF13083.1 KPI40059.1 - 5.1e-11 42.0 8.2 0.034 13.7 0.0 6.6 6 0 0 6 6 6 4 KH domain KH_2 PF07650.12 KPI40059.1 - 9.4e-09 34.7 18.3 0.12 11.8 0.0 7.3 7 0 0 7 7 7 4 KH domain SLS PF14611.1 KPI40059.1 - 1.9e-06 27.4 11.5 0.19 11.1 0.0 7.2 6 3 2 9 9 9 2 Mitochondrial inner-membrane-bound regulator BMC PF00936.14 KPI40059.1 - 0.0047 16.5 3.5 0.56 9.9 0.1 4.3 4 0 0 4 4 4 1 BMC domain DUF3218 PF11508.3 KPI40059.1 - 0.14 11.6 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3218) SHNi-TPR PF10516.4 KPI40060.1 - 7.9e-10 37.8 1.3 7.9e-10 37.8 0.9 2.6 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 KPI40060.1 - 2.7e-06 26.9 9.8 0.0055 16.3 0.5 2.9 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.1 KPI40060.1 - 1e-05 25.3 8.2 0.0073 16.2 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KPI40060.1 - 0.015 14.8 5.4 1.7 8.3 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KPI40060.1 - 0.026 15.1 0.4 0.026 15.1 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KPI40060.1 - 0.043 13.7 0.1 20 5.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat CCDC-167 PF15188.1 KPI40060.1 - 0.085 12.8 4.0 0.21 11.5 2.7 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Apc3 PF12895.2 KPI40060.1 - 0.15 12.2 8.8 2.5 8.2 0.5 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 KPI40060.1 - 0.51 10.2 3.4 7 6.5 0.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KPI40060.1 - 0.7 9.9 13.7 1.2 9.2 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat AATF-Che1 PF13339.1 KPI40060.1 - 4.6 7.3 15.9 0.31 11.2 1.0 3.7 2 1 2 4 4 4 0 Apoptosis antagonizing transcription factor HSP70 PF00012.15 KPI40061.1 - 2.6e-260 864.5 14.2 3.2e-260 864.2 9.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KPI40061.1 - 2.4e-20 72.4 3.2 1.3e-19 70.0 0.6 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KPI40061.1 - 0.0065 16.1 0.0 0.12 12.0 0.0 2.7 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KPI40061.1 - 0.11 11.5 0.1 0.11 11.5 0.1 2.9 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase tRNA-synt_2 PF00152.15 KPI40062.1 - 3.4e-51 174.0 0.0 3.8e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) PRCC PF10253.4 KPI40063.1 - 9.8e-35 120.8 8.1 9.8e-35 120.8 5.6 2.4 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting TFIIF_alpha PF05793.7 KPI40064.1 - 0.15 10.4 12.3 0.34 9.2 8.5 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Metallophos PF00149.23 KPI40066.1 - 0.00013 21.4 0.5 0.00017 21.0 0.4 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase UDG PF03167.14 KPI40067.1 - 7.6e-25 87.1 0.1 1.4e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily PX PF00787.19 KPI40067.1 - 6.2e-17 61.4 0.0 2e-16 59.8 0.0 1.9 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KPI40067.1 - 2.5e-07 30.2 16.7 0.001 18.3 2.7 2.3 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 KPI40067.1 - 0.00021 20.8 2.5 0.00021 20.8 1.8 2.0 2 0 0 2 2 2 1 BAR domain MRJP PF03022.11 KPI40068.1 - 3.6e-19 69.0 0.1 4.7e-19 68.6 0.1 1.1 1 0 0 1 1 1 1 Major royal jelly protein NHL PF01436.16 KPI40068.1 - 0.11 12.5 1.7 45 4.2 0.0 4.0 4 0 0 4 4 4 0 NHL repeat TROVE PF05731.6 KPI40069.1 - 0.037 12.7 0.4 0.05 12.3 0.3 1.1 1 0 0 1 1 1 0 TROVE domain TrwC PF08751.6 KPI40069.1 - 0.15 11.4 1.9 0.19 11.1 0.5 1.6 2 0 0 2 2 2 0 TrwC relaxase LytR_C PF13399.1 KPI40069.1 - 0.2 12.0 6.8 0.28 11.5 0.5 2.4 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator MFS_1 PF07690.11 KPI40070.1 - 5.4e-23 81.2 39.5 5.4e-23 81.2 27.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MerC PF03203.9 KPI40070.1 - 9 6.7 16.0 2.4 8.5 2.6 3.4 3 1 0 3 3 3 0 MerC mercury resistance protein FAD_binding_3 PF01494.14 KPI40071.1 - 5e-15 55.4 0.1 2.9e-06 26.5 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KPI40071.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Mito_carr PF00153.22 KPI40072.1 - 1.2e-42 143.5 0.4 1.1e-13 50.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2770 PF10968.3 KPI40073.1 - 1.2 8.8 5.1 0.16 11.6 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2770) 4HBT PF03061.17 KPI40074.1 - 5.5e-12 45.6 0.1 8.7e-12 44.9 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 KPI40074.1 - 0.0093 15.9 0.4 0.011 15.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Epimerase PF01370.16 KPI40076.1 - 2.1e-11 43.6 0.3 7.6e-08 32.0 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI40076.1 - 9.6e-11 42.0 0.3 2.3e-10 40.7 0.2 1.6 2 0 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KPI40076.1 - 1.3e-07 30.8 0.0 0.0065 15.3 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.8 KPI40076.1 - 7.6e-06 25.3 0.6 3.5e-05 23.1 0.2 2.1 2 1 1 3 3 3 1 NmrA-like family 3Beta_HSD PF01073.14 KPI40076.1 - 0.0003 19.5 0.0 0.00078 18.2 0.1 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KPI40076.1 - 0.00059 18.8 0.1 0.001 18.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KPI40076.1 - 0.0091 15.9 1.9 0.02 14.8 1.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 KPI40076.1 - 0.093 12.6 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 KPI40076.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 KPI40076.1 - 0.12 11.7 0.1 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 KPI40076.1 - 0.13 11.8 0.3 0.22 11.0 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CBP4 PF07960.6 KPI40077.1 - 0.013 15.1 0.0 0.038 13.6 0.0 1.7 2 0 0 2 2 2 0 CBP4 DUF3278 PF11683.3 KPI40078.1 - 0.09 12.7 3.3 0.15 12.0 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) DUF1700 PF08006.6 KPI40078.1 - 0.31 10.3 4.7 0.56 9.4 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Rhodanese PF00581.15 KPI40079.1 - 2.3e-13 50.4 0.0 6e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Glyoxalase_2 PF12681.2 KPI40080.1 - 7.9e-08 32.8 0.0 2.5e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KPI40080.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short PF00106.20 KPI40081.1 - 2e-23 83.1 0.0 4.2e-23 82.0 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI40081.1 - 4.2e-07 29.7 0.0 0.00032 20.4 0.0 2.4 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KPI40081.1 - 5.3e-06 26.3 0.0 1.5e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KPI40081.1 - 0.0016 18.1 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KPI40081.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ACPS PF01648.15 KPI40082.1 - 1.7e-08 34.3 0.1 1.8e-07 30.9 0.1 2.2 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily PFU PF09070.6 KPI40084.1 - 1.5e-42 144.3 0.8 2.6e-42 143.5 0.5 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 KPI40084.1 - 1.4e-32 110.3 13.2 1.3e-06 28.0 0.0 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat PUL PF08324.6 KPI40084.1 - 2e-27 95.6 0.3 2.7e-27 95.2 0.2 1.2 1 0 0 1 1 1 1 PUL domain TRP PF06011.7 KPI40085.1 - 1.4e-127 425.9 13.7 1.9e-127 425.4 9.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KPI40085.1 - 7.8e-40 136.1 0.3 1.3e-39 135.4 0.2 1.4 1 0 0 1 1 1 1 ML-like domain Shisa PF13908.1 KPI40085.1 - 0.0017 18.5 0.7 0.0017 18.5 0.5 2.6 2 1 1 3 3 3 1 Wnt and FGF inhibitory regulator DUF1469 PF07332.6 KPI40085.1 - 0.0042 16.8 0.7 0.0042 16.8 0.5 4.5 5 1 1 6 6 6 1 Protein of unknown function (DUF1469) EphA2_TM PF14575.1 KPI40085.1 - 1.3 9.4 0.0 1.3 9.4 0.0 4.2 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Flavokinase PF01687.12 KPI40086.1 - 8.8e-36 122.5 0.0 1.1e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Ank_2 PF12796.2 KPI40087.1 - 7.1e-07 29.4 0.0 7.7e-06 26.1 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KPI40087.1 - 0.00016 22.0 0.0 0.44 11.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KPI40087.1 - 0.0019 17.9 0.0 0.01 15.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 KPI40087.1 - 0.0086 16.2 0.0 0.056 13.7 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeat Methyltransf_31 PF13847.1 KPI40087.1 - 0.034 13.7 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ank_5 PF13857.1 KPI40087.1 - 0.088 13.0 0.0 2.6 8.4 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) OGG_N PF07934.7 KPI40088.1 - 2.6e-33 114.4 0.0 4.4e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KPI40088.1 - 8.2e-11 42.1 0.0 1.5e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Adeno_VII PF03228.9 KPI40088.1 - 0.11 13.0 2.5 0.22 12.1 1.8 1.6 1 0 0 1 1 1 0 Adenoviral core protein VII Zn_Tnp_IS1 PF03811.8 KPI40089.1 - 0.19 11.2 17.3 3.9 7.0 0.3 4.3 4 0 0 4 4 4 0 InsA N-terminal domain Transp_Tc5_C PF04236.10 KPI40089.1 - 0.5 10.6 7.4 2 8.7 0.1 3.3 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain zinc_ribbon_5 PF13719.1 KPI40089.1 - 1.2 8.8 14.8 13 5.4 0.3 4.3 4 0 0 4 4 4 0 zinc-ribbon domain zf-FPG_IleRS PF06827.9 KPI40089.1 - 1.3 8.7 14.9 11 5.8 0.3 4.4 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.5 KPI40089.1 - 6.1 6.8 7.9 1.4e+02 2.4 0.0 4.1 4 0 0 4 4 4 0 Zinc ribbon domain RNase_PH PF01138.16 KPI40090.1 - 4.9e-23 81.8 0.0 7.5e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KPI40090.1 - 6.6e-05 22.7 0.1 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MOZART2 PF12926.2 KPI40090.1 - 0.012 15.1 0.3 0.032 13.8 0.1 1.7 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated SPOC PF07744.8 KPI40091.1 - 1.5e-16 60.9 0.0 4e-16 59.5 0.0 1.7 2 0 0 2 2 2 1 SPOC domain PHD PF00628.24 KPI40091.1 - 1.2e-09 37.7 12.5 2.5e-09 36.6 8.7 1.6 1 0 0 1 1 1 1 PHD-finger TFIIS_M PF07500.9 KPI40091.1 - 3.2e-09 36.8 0.0 3.2e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD_2 PF13831.1 KPI40091.1 - 0.0069 15.6 6.4 0.012 14.9 4.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 KPI40091.1 - 0.072 13.3 1.7 0.29 11.4 1.2 2.1 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Aldo_ket_red PF00248.16 KPI40092.1 - 1.8e-58 197.6 0.0 2.1e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_3 PF01494.14 KPI40093.1 - 5.2e-08 32.3 1.6 0.016 14.2 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KPI40093.1 - 0.0033 17.4 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KPI40093.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KPI40093.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI40093.1 - 0.13 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.27 KPI40094.1 - 1e-55 183.7 24.8 2.8e-12 45.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KPI40094.1 - 0.00017 19.9 7.3 0.3 9.1 0.1 3.6 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KPI40094.1 - 0.0053 15.0 0.0 0.46 8.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain zf-LITAF-like PF10601.4 KPI40095.1 - 2.4e-13 49.7 9.4 3.4e-13 49.2 6.5 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Cys_rich_KTR PF14205.1 KPI40095.1 - 0.069 12.6 1.5 0.43 10.0 0.1 2.2 2 0 0 2 2 2 0 Cysteine-rich KTR zf-H2C2_2 PF13465.1 KPI40095.1 - 0.25 11.7 3.0 9.8 6.6 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Glyco_hydro_31 PF01055.21 KPI40096.1 - 3.6e-85 286.4 8.6 6.3e-85 285.6 6.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Sugar_tr PF00083.19 KPI40097.1 - 6.5e-104 348.0 20.5 8.2e-104 347.6 14.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI40097.1 - 2.2e-24 85.8 24.3 2.2e-24 85.8 16.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI40097.1 - 9.4e-06 24.2 0.1 9.4e-06 24.2 0.1 3.7 4 0 0 4 4 4 2 MFS/sugar transport protein DUF791 PF05631.9 KPI40097.1 - 0.00018 20.3 0.4 0.00044 19.0 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF791) VHS PF00790.14 KPI40098.1 - 2e-40 137.6 3.9 4.4e-40 136.5 0.3 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 KPI40098.1 - 1.2e-16 60.3 2.3 2e-16 59.6 1.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 KPI40098.1 - 2.9e-06 26.3 11.2 0.0052 16.2 0.9 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-DHHC PF01529.15 KPI40098.1 - 0.025 13.9 0.1 0.025 13.9 0.1 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase FYVE_2 PF02318.11 KPI40098.1 - 0.033 14.0 0.6 0.071 13.0 0.4 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger ENTH PF01417.15 KPI40098.1 - 0.04 13.7 0.3 0.074 12.9 0.2 1.4 1 0 0 1 1 1 0 ENTH domain C1_1 PF00130.17 KPI40098.1 - 0.058 13.1 2.9 0.12 12.1 2.0 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Amidohydro_5 PF13594.1 KPI40099.1 - 1.1e-14 53.9 0.4 1e-13 50.8 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 KPI40099.1 - 2.5e-06 27.3 0.0 2.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KPI40099.1 - 0.021 14.8 0.3 0.04 13.9 0.1 1.8 2 1 0 2 2 2 0 Amidohydrolase TGT_C2 PF14810.1 KPI40099.1 - 0.046 13.5 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Patch-forming domain C2 of tRNA-guanine transglycosylase AAA_5 PF07728.9 KPI40100.1 - 1.2e-122 404.0 0.1 2.1e-21 76.1 0.0 9.9 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KPI40100.1 - 8.3e-29 99.8 0.0 1.2e-12 47.5 0.0 6.9 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KPI40100.1 - 2.1e-24 86.2 0.0 0.0002 21.5 0.0 6.9 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KPI40100.1 - 1.6e-16 61.1 0.1 0.049 14.4 0.0 7.3 6 0 0 6 6 6 4 AAA domain AAA_22 PF13401.1 KPI40100.1 - 4.1e-15 56.0 5.2 0.24 11.5 0.0 8.7 9 0 0 9 9 8 3 AAA domain AAA_14 PF13173.1 KPI40100.1 - 5.4e-15 55.4 0.0 0.067 13.0 0.0 7.8 8 0 0 8 8 7 3 AAA domain AAA_33 PF13671.1 KPI40100.1 - 1.5e-13 50.8 0.2 1.4 8.8 0.0 7.4 6 1 0 6 6 6 4 AAA domain AAA_18 PF13238.1 KPI40100.1 - 8e-12 45.5 3.9 0.47 10.7 0.0 7.3 7 0 0 7 7 6 1 AAA domain Sigma54_activ_2 PF14532.1 KPI40100.1 - 3.6e-11 43.2 1.2 0.14 12.1 0.0 6.3 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA_16 PF13191.1 KPI40100.1 - 3.7e-11 43.3 34.1 0.00035 20.6 0.4 9.0 10 1 1 11 11 9 4 AAA ATPase domain AAA_19 PF13245.1 KPI40100.1 - 1.4e-10 40.7 9.4 0.042 13.5 0.0 5.7 5 0 0 5 5 5 3 Part of AAA domain UPF0079 PF02367.12 KPI40100.1 - 4.3e-10 39.2 0.5 2.8 7.6 0.0 6.4 6 0 0 6 6 6 2 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 KPI40100.1 - 1.4e-09 38.4 0.9 1.4 9.4 0.1 6.6 6 0 0 6 6 6 1 Miro-like protein Sigma54_activat PF00158.21 KPI40100.1 - 1.5e-09 37.5 0.1 0.27 10.6 0.0 5.2 5 0 0 5 5 5 3 Sigma-54 interaction domain ABC_tran PF00005.22 KPI40100.1 - 1e-08 35.5 0.4 0.81 9.9 0.0 6.1 5 0 0 5 5 5 2 ABC transporter Zeta_toxin PF06414.7 KPI40100.1 - 3.1e-08 32.9 1.3 0.057 12.5 0.0 5.9 6 0 0 6 6 5 1 Zeta toxin RNA_helicase PF00910.17 KPI40100.1 - 4.5e-08 33.2 0.5 5 7.3 0.0 6.4 6 0 0 6 6 6 0 RNA helicase AAA_25 PF13481.1 KPI40100.1 - 8.6e-08 31.8 1.1 1.1 8.5 0.0 5.9 5 0 0 5 5 5 1 AAA domain NACHT PF05729.7 KPI40100.1 - 9.3e-08 31.9 2.6 0.04 13.5 0.0 5.0 5 0 0 5 5 4 2 NACHT domain Arch_ATPase PF01637.13 KPI40100.1 - 1.7e-07 31.2 0.0 1.6 8.4 0.0 5.2 5 0 0 5 5 5 1 Archaeal ATPase MobB PF03205.9 KPI40100.1 - 3.8e-07 29.8 2.9 4.2 7.0 0.1 6.1 6 0 0 6 6 5 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KPI40100.1 - 1.2e-06 28.5 2.7 15 5.4 0.0 6.8 6 0 0 6 6 6 0 AAA domain RuvB_N PF05496.7 KPI40100.1 - 2.5e-06 26.7 2.0 0.99 8.3 0.0 5.1 6 0 0 6 6 5 2 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 KPI40100.1 - 2.9e-06 26.7 1.1 1.7 8.2 0.0 5.0 5 0 0 5 5 4 1 P-loop containing region of AAA domain TIP49 PF06068.8 KPI40100.1 - 6.8e-06 25.0 0.3 0.058 12.0 0.0 3.9 5 0 0 5 5 5 2 TIP49 C-terminus DUF258 PF03193.11 KPI40100.1 - 7.2e-06 25.2 3.4 0.061 12.5 0.1 5.1 5 0 0 5 5 5 1 Protein of unknown function, DUF258 Viral_helicase1 PF01443.13 KPI40100.1 - 4.3e-05 23.1 0.3 0.14 11.6 0.0 4.9 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.4 KPI40100.1 - 0.00013 21.5 0.8 0.95 8.9 0.0 4.2 5 0 0 5 5 4 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KPI40100.1 - 0.00018 21.4 0.7 7.7 6.5 0.0 5.1 4 0 0 4 4 4 0 50S ribosome-binding GTPase Bac_DnaA PF00308.13 KPI40100.1 - 0.00058 19.5 0.0 0.33 10.5 0.0 4.2 5 0 0 5 5 5 1 Bacterial dnaA protein PhoH PF02562.11 KPI40100.1 - 0.0091 15.2 0.6 3 7.0 0.0 4.0 4 0 0 4 4 4 1 PhoH-like protein NTPase_1 PF03266.10 KPI40100.1 - 0.011 15.4 9.5 9.5 5.8 0.0 5.0 5 0 0 5 5 5 0 NTPase ATP-synt_ab PF00006.20 KPI40100.1 - 0.015 14.7 0.0 10 5.5 0.0 4.1 5 0 0 5 5 5 0 ATP synthase alpha/beta family, nucleotide-binding domain KaiC PF06745.8 KPI40100.1 - 0.024 13.7 0.8 20 4.1 0.0 4.6 6 0 0 6 6 5 0 KaiC AAA_6 PF12774.2 KPI40100.1 - 0.025 14.1 0.0 11 5.4 0.0 4.6 4 1 0 4 4 4 0 Hydrolytic ATP binding site of dynein motor region D1 AAA_7 PF12775.2 KPI40100.1 - 0.034 13.2 0.4 69 2.3 0.0 4.1 4 0 0 4 4 4 0 P-loop containing dynein motor region D3 Mito_carr PF00153.22 KPI40101.1 - 5.3e-57 189.5 2.0 6.1e-20 70.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PAN_4 PF14295.1 KPI40102.1 - 1.6e-13 50.1 5.6 6.9e-07 28.8 0.4 2.5 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.21 KPI40102.1 - 6.1e-13 48.3 3.0 1.5e-05 24.6 0.1 3.3 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.6 KPI40102.1 - 0.0026 17.5 4.4 0.21 11.4 0.1 2.7 2 0 0 2 2 2 2 PAN-like domain MANEC PF07502.9 KPI40102.1 - 0.053 13.5 0.8 1.7 8.7 0.1 2.6 2 0 0 2 2 2 0 MANEC domain PAN_3 PF08277.7 KPI40102.1 - 0.056 13.0 2.1 4 7.1 0.2 3.1 2 0 0 2 2 2 0 PAN-like domain CBFB_NFYA PF02045.10 KPI40103.1 - 0.016 15.7 0.8 0.029 14.9 0.6 1.4 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Peptidase_M20 PF01546.23 KPI40106.1 - 2.2e-13 50.1 0.1 2.7e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KPI40106.1 - 4.8e-06 26.2 0.0 8.4e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KPI40106.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 SCA7 PF08313.7 KPI40107.1 - 2.8e-33 113.3 2.2 2.8e-33 113.3 1.6 2.2 2 1 0 3 3 3 1 SCA7, zinc-binding domain Prothymosin PF03247.9 KPI40107.1 - 0.0019 18.3 19.9 0.0019 18.3 13.8 1.9 2 0 0 2 2 2 1 Prothymosin/parathymosin family Nop14 PF04147.7 KPI40107.1 - 0.0054 14.7 13.5 0.0055 14.7 9.4 1.2 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 KPI40107.1 - 0.081 10.9 12.5 0.09 10.7 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein TLP-20 PF06088.6 KPI40107.1 - 2.3 7.8 9.1 3.7 7.1 6.3 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) NPR3 PF03666.8 KPI40107.1 - 3.5 6.0 7.5 5.7 5.3 5.2 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2306 PF10067.4 KPI40108.1 - 1.9e-10 40.7 9.1 1.9e-10 40.7 6.3 2.2 3 1 0 3 3 3 1 Predicted membrane protein (DUF2306) DUF420 PF04238.7 KPI40108.1 - 0.014 15.3 3.9 0.014 15.3 2.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF420) PrgI PF12666.2 KPI40108.1 - 0.11 12.7 5.0 0.088 12.9 1.1 2.6 1 1 1 2 2 2 0 PrgI family protein Fungal_trans PF04082.13 KPI40110.1 - 4e-12 45.5 2.1 7.6e-12 44.6 1.4 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.20 KPI40111.1 - 1.3e-16 61.0 0.2 2.4e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI40111.1 - 2.9e-07 30.3 0.1 5.1e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI40111.1 - 0.00084 18.8 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KPI40111.1 - 0.0013 18.5 0.1 0.013 15.2 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KPI40111.1 - 0.062 13.3 0.8 0.89 9.5 0.0 2.5 2 1 1 3 3 3 0 NADH(P)-binding Shikimate_DH PF01488.15 KPI40111.1 - 0.066 13.3 0.2 0.21 11.6 0.0 1.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Peptidase_M24 PF00557.19 KPI40112.1 - 9.7e-39 133.0 0.3 6.5e-38 130.4 0.2 2.1 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KPI40112.1 - 2.4e-37 127.3 0.0 3.9e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Abhydrolase_6 PF12697.2 KPI40113.1 - 2.8e-07 30.6 2.2 2.8e-07 30.6 1.5 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI40113.1 - 0.03 14.0 0.0 0.052 13.3 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Asp_Glu_race PF01177.17 KPI40114.1 - 6.1e-26 91.6 0.1 8.1e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase zf-RING_4 PF14570.1 KPI40115.1 - 4.8e-17 61.2 13.3 8e-17 60.5 9.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 KPI40115.1 - 3.3e-06 26.6 7.2 5.7e-06 25.9 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KPI40115.1 - 0.00017 21.3 10.0 0.00027 20.6 7.0 1.4 1 0 0 1 1 1 1 Ring finger domain RRM_1 PF00076.17 KPI40115.1 - 0.00041 19.9 0.0 0.001 18.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 KPI40115.1 - 0.0014 17.8 4.2 0.0014 17.8 2.9 4.2 4 1 0 4 4 4 1 Rtf2 RING-finger RRM_5 PF13893.1 KPI40115.1 - 0.0035 17.1 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_5 PF14634.1 KPI40115.1 - 0.58 9.9 11.6 0.97 9.2 8.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 KPI40115.1 - 0.62 9.7 12.1 1.1 8.9 8.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 KPI40115.1 - 1.1 8.9 6.7 2 8.1 4.7 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_2 PF13923.1 KPI40115.1 - 3.4 7.7 11.5 5.8 7.0 8.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fungal_trans PF04082.13 KPI40116.1 - 1.4e-07 30.6 0.0 3.9e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain UCH PF00443.24 KPI40117.1 - 4.8e-78 261.9 0.0 2.1e-77 259.8 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KPI40117.1 - 7.2e-19 68.3 0.0 1.2e-09 38.0 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_M48 PF01435.13 KPI40118.1 - 2.8e-34 118.6 0.0 4.1e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 MAPEG PF01124.13 KPI40119.1 - 5.4e-21 74.5 1.7 7.4e-21 74.0 1.2 1.1 1 0 0 1 1 1 1 MAPEG family Fungal_trans_2 PF11951.3 KPI40120.1 - 7.5e-13 47.8 0.1 1e-12 47.4 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain AIRC PF00731.15 KPI40121.1 - 7.1e-27 93.5 0.1 8.6e-27 93.2 0.0 1.1 1 0 0 1 1 1 1 AIR carboxylase DUF746 PF05344.6 KPI40121.1 - 0.096 12.2 0.1 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Filament PF00038.16 KPI40122.1 - 0.00013 21.5 64.6 0.00082 18.9 29.9 2.5 2 0 0 2 2 2 2 Intermediate filament protein Laminin_II PF06009.7 KPI40122.1 - 0.023 14.4 0.7 0.023 14.4 0.5 5.7 2 1 1 5 5 5 0 Laminin Domain II GAS PF13851.1 KPI40122.1 - 0.064 12.4 74.8 0.06 12.5 11.1 5.7 2 2 3 5 5 5 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 KPI40122.1 - 0.072 13.2 44.7 0.3 11.2 8.1 4.5 3 1 0 4 4 4 0 Fibrinogen alpha/beta chain family WEMBL PF05701.6 KPI40122.1 - 0.16 10.3 75.3 0.024 13.1 33.0 2.6 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DASH_Dam1 PF08653.5 KPI40122.1 - 0.3 10.8 3.7 6.1 6.6 0.1 3.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 ATG16 PF08614.6 KPI40122.1 - 0.68 9.7 70.3 0.3 10.9 5.4 4.9 1 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 KPI40122.1 - 0.84 9.4 80.8 0.3 10.9 7.1 4.7 2 1 2 4 4 4 0 Tropomyosin like MscS_porin PF12795.2 KPI40122.1 - 0.94 8.7 68.1 2.4 7.4 22.2 3.9 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain IncA PF04156.9 KPI40122.1 - 1.8 8.1 71.0 0.64 9.5 6.0 4.3 2 1 2 4 4 4 0 IncA protein Spc7 PF08317.6 KPI40122.1 - 3.2 6.3 57.0 0.37 9.3 9.1 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 KPI40122.1 - 7 6.4 61.4 0.31 10.7 2.8 6.3 2 2 4 7 7 7 0 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 KPI40122.1 - 8 5.5 21.2 7.9 5.5 3.8 3.9 1 1 2 4 4 4 0 Reovirus sigma C capsid protein 2-Hacid_dh_C PF02826.14 KPI40123.1 - 7.2e-55 184.8 0.0 1.1e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KPI40123.1 - 7.7e-37 125.7 0.0 1.7e-36 124.6 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 KPI40123.1 - 0.082 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Transaldolase PF00923.14 KPI40124.1 - 5.6e-35 120.8 0.0 9.2e-35 120.1 0.0 1.3 2 0 0 2 2 2 1 Transaldolase DUF2834 PF11196.3 KPI40125.1 - 0.054 13.6 5.4 1.9 8.6 1.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2834) MFS_1 PF07690.11 KPI40126.1 - 4.3e-35 121.0 40.3 7.3e-34 117.0 18.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily FxsA PF04186.8 KPI40128.1 - 0.032 13.8 0.9 0.064 12.8 0.6 1.5 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein DUF4013 PF13197.1 KPI40128.1 - 0.22 10.8 12.5 0.15 11.3 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4013) DEAD PF00270.24 KPI40129.1 - 9.4e-47 158.6 0.0 2.7e-45 153.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI40129.1 - 8.6e-28 96.0 0.0 1.1e-26 92.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI40129.1 - 5e-07 29.7 0.0 9.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KPI40129.1 - 5.2e-05 22.1 0.0 8.2e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain CMS1 PF14617.1 KPI40129.1 - 0.013 14.6 1.5 0.16 11.0 0.0 2.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit SBF PF01758.11 KPI40130.1 - 2.5e-48 163.9 11.2 2.5e-48 163.9 7.8 1.8 2 1 0 2 2 2 1 Sodium Bile acid symporter family DHFR_1 PF00186.14 KPI40131.1 - 1e-21 77.1 0.0 1.5e-09 37.6 0.0 3.2 3 0 0 3 3 3 3 Dihydrofolate reductase Rer1 PF03248.8 KPI40133.1 - 0.44 10.1 1.1 19 4.7 0.1 2.2 2 0 0 2 2 2 0 Rer1 family PNP_UDP_1 PF01048.15 KPI40134.1 - 5.2e-26 91.0 0.2 1.2e-25 89.8 0.1 1.5 1 1 1 2 2 2 1 Phosphorylase superfamily CTP_transf_2 PF01467.21 KPI40135.1 - 5.3e-22 78.5 0.0 6.5e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase zf-Nse PF11789.3 KPI40136.1 - 2.2e-17 62.3 0.1 4.5e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DPPIV_N PF00930.16 KPI40137.1 - 2.1e-84 283.1 0.4 2.4e-82 276.3 0.2 2.2 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KPI40137.1 - 8.7e-49 165.6 0.3 1.5e-48 164.8 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KPI40137.1 - 1.7e-08 34.3 0.1 3.5e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI40137.1 - 6.2e-06 26.2 0.1 4.6e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KPI40137.1 - 0.00064 19.2 1.0 0.003 17.0 0.7 2.0 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Coatomer_WDAD PF04053.9 KPI40137.1 - 0.16 10.7 0.0 4.7 5.8 0.0 2.2 1 1 1 2 2 2 0 Coatomer WD associated region PAF-AH_p_II PF03403.8 KPI40137.1 - 0.16 10.2 0.0 0.24 9.6 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Rft-1 PF04506.8 KPI40138.1 - 6.6e-58 196.4 0.0 1.5e-56 191.9 0.0 2.0 1 1 0 1 1 1 1 Rft protein DUF1328 PF07043.8 KPI40138.1 - 0.43 10.5 7.6 1.2 9.1 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1328) Rax2 PF12768.2 KPI40139.1 - 6.2e-79 265.1 5.3 2.6e-70 236.8 0.1 4.6 4 0 0 4 4 4 3 Cortical protein marker for cell polarity Kelch_6 PF13964.1 KPI40139.1 - 0.0006 19.8 11.8 6.8 7.0 0.0 8.3 6 2 2 8 8 8 1 Kelch motif Kelch_3 PF13415.1 KPI40139.1 - 0.0074 16.4 14.0 2.4 8.4 0.0 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.1 KPI40139.1 - 0.015 15.0 9.4 1.5 8.6 0.2 4.9 5 0 0 5 5 5 0 Galactose oxidase, central domain Kelch_1 PF01344.20 KPI40139.1 - 0.032 13.7 9.1 3.4 7.2 0.1 4.8 5 0 0 5 5 5 0 Kelch motif DUF3425 PF11905.3 KPI40140.1 - 1.5e-16 60.5 0.0 4.8e-16 58.8 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) DUF3505 PF12013.3 KPI40141.1 - 0.00043 20.4 0.1 0.0012 19.0 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3505) zf-C2H2_jaz PF12171.3 KPI40141.1 - 0.00099 19.1 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KPI40141.1 - 0.0034 17.5 0.3 0.0055 16.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KPI40141.1 - 0.07 13.2 0.3 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) FAM60A PF15396.1 KPI40141.1 - 1 9.0 11.3 3.4 7.3 7.9 2.0 1 1 0 1 1 1 0 Protein Family FAM60A Methyltransf_23 PF13489.1 KPI40142.1 - 4.9e-18 65.3 0.0 6.9e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI40142.1 - 3.3e-10 39.7 0.0 2.1e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI40142.1 - 3.6e-10 40.1 0.0 6.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI40142.1 - 6.9e-10 39.4 0.0 1.1e-08 35.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI40142.1 - 3.2e-07 30.6 0.0 6.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI40142.1 - 1.5e-06 28.6 0.0 1.1e-05 25.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI40142.1 - 0.00087 18.4 0.0 0.044 12.8 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KPI40142.1 - 0.0014 18.6 0.0 0.0042 17.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KPI40142.1 - 0.0067 15.8 0.0 0.03 13.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 KPI40142.1 - 0.0089 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 KPI40142.1 - 0.025 13.6 0.0 0.071 12.1 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.8 KPI40142.1 - 0.038 13.1 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 KPI40142.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MFS_1 PF07690.11 KPI40143.1 - 5.5e-36 124.0 28.3 5.5e-36 124.0 19.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI40143.1 - 4.9e-12 45.1 8.5 4.9e-12 45.1 5.9 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 KPI40143.1 - 0.083 10.9 3.7 0.093 10.7 0.9 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans_2 PF11951.3 KPI40144.1 - 7.1e-13 47.9 0.0 1.2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI40144.1 - 6.8e-07 29.0 9.2 1.1e-06 28.4 6.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Resolvase PF00239.16 KPI40144.1 - 0.087 12.6 0.1 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Resolvase, N terminal domain UCH PF00443.24 KPI40145.1 - 3.4e-54 183.7 0.0 6.3e-54 182.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KPI40145.1 - 2e-25 89.8 0.0 3.9e-25 88.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 KPI40145.1 - 0.0014 18.9 0.0 0.0036 17.6 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Rubredoxin PF00301.15 KPI40145.1 - 0.013 15.4 0.6 0.043 13.7 0.4 1.9 1 0 0 1 1 1 0 Rubredoxin zf-MIZ PF02891.15 KPI40145.1 - 0.16 11.5 0.8 0.36 10.3 0.6 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF1682 PF07946.9 KPI40146.1 - 4.2e-102 341.2 1.5 5.3e-102 340.9 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF2985 PF11204.3 KPI40146.1 - 0.035 13.8 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) Pantoate_transf PF02548.10 KPI40147.1 - 1.6e-101 338.8 0.3 1.9e-101 338.6 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KPI40147.1 - 6.4e-11 41.9 2.2 1.5e-10 40.7 1.5 1.6 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Sugar_tr PF00083.19 KPI40148.1 - 5.2e-97 325.2 28.3 6.1e-97 325.0 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI40148.1 - 5e-24 84.6 53.1 6.9e-22 77.6 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Clr5 PF14420.1 KPI40149.1 - 1.6e-12 47.1 1.4 3.3e-12 46.1 0.1 2.1 2 0 0 2 2 2 1 Clr5 domain TPR_12 PF13424.1 KPI40149.1 - 1.9e-08 34.0 2.9 0.00057 19.7 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 KPI40149.1 - 2e-05 24.3 2.1 0.078 12.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KPI40149.1 - 0.0005 19.6 0.0 0.041 13.5 0.0 2.6 1 1 2 3 3 3 2 TPR repeat TPR_2 PF07719.12 KPI40149.1 - 0.021 14.6 0.3 17 5.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KPI40149.1 - 0.03 13.9 0.0 2.8 7.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KPI40149.1 - 0.057 13.2 0.3 62 3.7 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PAN_1 PF00024.21 KPI40150.1 - 0.00012 21.7 4.3 0.00012 21.7 3.0 2.3 2 0 0 2 2 2 1 PAN domain PAN_3 PF08277.7 KPI40150.1 - 0.00015 21.2 1.9 0.00015 21.2 1.3 2.1 2 0 0 2 2 2 1 PAN-like domain PAN_4 PF14295.1 KPI40150.1 - 0.00016 21.2 1.4 0.00037 20.1 1.0 1.5 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 KPI40150.1 - 0.012 15.4 1.4 0.03 14.1 1.0 1.7 1 0 0 1 1 1 0 PAN-like domain Pyridoxal_deC PF00282.14 KPI40151.1 - 4e-22 78.1 0.0 4.2e-18 64.9 0.0 3.1 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain SLA_LP_auto_ag PF05889.8 KPI40151.1 - 0.088 11.2 0.0 0.15 10.4 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) YjeF_N PF03853.10 KPI40152.1 - 1.3e-34 119.2 0.0 1.6e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus ADH_zinc_N PF00107.21 KPI40153.1 - 7.7e-28 96.6 0.3 1.2e-27 95.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI40153.1 - 1.8e-09 38.5 0.1 4.6e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AA_kinase PF00696.23 KPI40153.1 - 0.0099 15.4 0.1 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family DUF155 PF02582.9 KPI40154.1 - 8.6e-56 188.5 0.1 1.7e-55 187.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Ras PF00071.17 KPI40154.1 - 1.5e-34 118.7 0.0 3.2e-20 72.1 0.0 2.3 1 1 1 2 2 2 2 Ras family Miro PF08477.8 KPI40154.1 - 4.7e-09 36.7 0.0 6.3e-07 29.9 0.0 3.0 2 1 0 2 2 2 1 Miro-like protein Erg28 PF03694.8 KPI40155.1 - 1.6e-08 34.4 0.1 2.1e-08 34.1 0.1 1.1 1 0 0 1 1 1 1 Erg28 like protein Alg6_Alg8 PF03155.10 KPI40156.1 - 1.3e-138 462.8 28.1 1.7e-138 462.4 19.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF4298 PF14131.1 KPI40157.1 - 0.11 12.3 2.1 0.43 10.4 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Acetyltransf_1 PF00583.19 KPI40158.1 - 9.8e-13 47.9 0.0 2.8e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI40158.1 - 1.6e-06 28.2 0.0 7.3e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KPI40158.1 - 0.00012 21.7 0.0 0.026 14.2 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_9 PF13527.1 KPI40158.1 - 0.00027 20.8 0.8 0.0074 16.1 0.1 2.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI40158.1 - 0.0014 18.7 0.0 0.014 15.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Mec-17 PF05301.6 KPI40158.1 - 0.0014 18.5 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Touch receptor neuron protein Mec-17 Acetyltransf_CG PF14542.1 KPI40158.1 - 0.027 14.3 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pyridox_ox_2 PF12900.2 KPI40159.1 - 2.1e-34 118.4 0.0 2.8e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SMP PF04927.7 KPI40160.1 - 8.1e-10 38.5 4.9 0.071 13.0 0.1 4.2 3 1 1 4 4 4 4 Seed maturation protein ASCH PF04266.9 KPI40160.1 - 0.07 13.5 0.7 3.2 8.1 0.0 2.7 2 1 1 3 3 3 0 ASCH domain HAD_2 PF13419.1 KPI40161.1 - 3.7e-12 46.8 0.2 1e-11 45.4 0.1 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Lactamase_B PF00753.22 KPI40162.1 - 4.1e-14 52.6 2.3 6.5e-14 52.0 1.6 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI40162.1 - 6.8e-05 22.4 0.0 0.00019 21.0 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Nup54 PF13874.1 KPI40164.1 - 0.24 11.0 6.9 0.76 9.4 4.8 1.8 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Transket_pyr PF02779.19 KPI40165.1 - 1.6e-44 151.4 0.1 2.8e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KPI40165.1 - 5e-30 103.9 0.1 1.1e-29 102.8 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain RRM_1 PF00076.17 KPI40166.1 - 4.4e-18 64.6 0.2 9.1e-18 63.6 0.1 1.5 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI40166.1 - 1.9e-12 46.9 0.0 2.8e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI40166.1 - 2.3e-10 40.1 0.1 3.4e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADH_zinc_N PF00107.21 KPI40167.1 - 4.5e-17 61.8 0.0 9.9e-17 60.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI40167.1 - 1.8e-14 54.7 0.1 4.5e-14 53.4 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI40167.1 - 0.013 15.2 0.0 1.2 8.9 0.0 2.3 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain Peptidase_M3 PF01432.15 KPI40168.1 - 2.3e-112 376.3 0.0 3.6e-112 375.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 KPI40168.1 - 0.086 12.2 0.3 0.14 11.4 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like His_Phos_1 PF00300.17 KPI40169.1 - 1.5e-10 41.4 1.3 3.1e-10 40.3 0.0 2.1 2 2 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Ribonuc_L-PSP PF01042.16 KPI40170.1 - 1.4e-12 47.4 0.0 1.7e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP TraC_F_IV PF11130.3 KPI40170.1 - 0.057 12.8 0.0 0.063 12.7 0.0 1.1 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer Proteasome PF00227.21 KPI40171.1 - 1.1e-59 200.8 0.2 1.4e-59 200.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KPI40171.1 - 3.7e-12 45.3 0.1 9.4e-12 44.0 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 KPI40171.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Proteasome PF00227.21 KPI40172.1 - 2.9e-44 150.6 0.1 3.7e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KPI40172.1 - 7.1e-13 47.5 1.5 7.1e-13 47.5 1.0 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal RRM_1 PF00076.17 KPI40173.1 - 3.9e-16 58.4 0.0 5.5e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI40173.1 - 1.3e-12 47.5 0.0 1.9e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI40173.1 - 2.6e-09 36.7 0.0 4.1e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_62 PF03664.8 KPI40174.1 - 1.2e-84 283.6 9.4 1.4e-84 283.4 6.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Tachylectin PF14517.1 KPI40174.1 - 0.0019 17.5 0.6 0.0075 15.6 0.1 2.4 2 1 0 2 2 2 1 Tachylectin Pyr_redox_3 PF13738.1 KPI40175.1 - 1.5e-26 93.7 0.0 2.4e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI40175.1 - 1.3e-15 56.6 0.0 2e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI40175.1 - 1e-09 38.2 0.0 4.6e-09 36.1 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI40175.1 - 6.3e-08 32.7 0.0 7.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI40175.1 - 1.3e-05 24.3 0.0 0.00021 20.2 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KPI40175.1 - 0.00015 21.5 0.2 0.024 14.3 0.0 2.9 2 1 1 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KPI40175.1 - 0.0002 20.5 0.1 0.00082 18.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KPI40175.1 - 0.026 13.5 0.3 0.048 12.7 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KPI40175.1 - 0.03 12.8 0.4 0.25 9.7 0.1 2.3 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.19 KPI40175.1 - 0.099 11.4 0.1 0.23 10.2 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain Aldo_ket_red PF00248.16 KPI40176.1 - 3.2e-67 226.3 0.0 3.7e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.19 KPI40177.1 - 1.2e-71 241.6 17.1 1.4e-71 241.4 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI40177.1 - 1.3e-16 60.3 16.7 1.3e-16 60.3 11.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KPI40177.1 - 0.00013 20.5 15.2 0.0038 15.6 3.1 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein E1-E2_ATPase PF00122.15 KPI40178.1 - 1.4e-66 223.8 5.2 1.6e-66 223.6 2.8 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KPI40178.1 - 1.2e-46 158.5 1.2 1.2e-46 158.5 0.9 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KPI40178.1 - 9.7e-29 101.3 0.0 6.9e-28 98.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KPI40178.1 - 5.1e-18 64.2 0.1 1e-17 63.3 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KPI40178.1 - 3.1e-14 53.6 0.0 7.6e-14 52.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KPI40178.1 - 8.6e-13 48.0 0.0 1.8e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KPI40178.1 - 0.00012 21.8 2.7 0.00016 21.3 0.8 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ATG22 PF11700.3 KPI40179.1 - 8e-203 674.2 18.7 9e-203 674.0 12.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KPI40179.1 - 0.018 13.7 59.0 0.39 9.3 6.4 3.1 2 1 1 3 3 3 0 Major Facilitator Superfamily Fungal_trans PF04082.13 KPI40180.1 - 1.7e-19 69.7 0.4 2.4e-19 69.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI40180.1 - 8.7e-08 31.9 8.2 1.5e-07 31.2 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KPI40180.1 - 0.13 12.4 6.3 0.39 10.9 4.3 1.8 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Hexokinase_2 PF03727.11 KPI40181.1 - 5.8e-76 254.9 0.0 8.8e-76 254.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KPI40181.1 - 2.5e-72 242.5 0.0 1.3e-71 240.1 0.0 1.9 2 0 0 2 2 2 1 Hexokinase NAD_binding_10 PF13460.1 KPI40182.1 - 2.5e-17 63.4 0.0 3e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KPI40182.1 - 2.3e-05 23.5 0.0 3.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 KPI40182.1 - 6.6e-05 22.2 0.0 8.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KPI40182.1 - 0.00099 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI40182.1 - 0.048 12.3 0.0 0.062 12.0 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KPI40182.1 - 0.16 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans_2 PF11951.3 KPI40184.1 - 1.5e-13 50.1 0.6 3.2e-13 49.0 0.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Methyltransf_18 PF12847.2 KPI40185.1 - 1.5e-07 32.0 0.0 5e-07 30.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI40185.1 - 1.5e-06 28.0 0.0 2.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI40185.1 - 1.8e-06 27.6 0.0 4.4e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI40185.1 - 5e-06 26.9 0.0 1.1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI40185.1 - 2e-05 24.9 0.0 4.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI40185.1 - 0.00021 21.3 0.0 0.00052 20.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI40185.1 - 0.0058 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI40185.1 - 0.13 11.3 0.0 0.36 9.8 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Glutaminase PF04960.10 KPI40186.1 - 2.4e-98 328.6 1.8 2.9e-98 328.3 1.2 1.1 1 0 0 1 1 1 1 Glutaminase STAS PF01740.16 KPI40186.1 - 0.082 12.3 0.0 0.91 8.9 0.0 2.3 1 1 0 1 1 1 0 STAS domain Meth_synt_2 PF01717.13 KPI40187.1 - 1.1e-12 47.5 0.0 5.7e-10 38.6 0.0 2.3 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KPI40187.1 - 0.0039 16.5 0.0 0.012 14.8 0.0 1.8 2 0 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain Apyrase PF06079.6 KPI40187.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Apyrase RRM_1 PF00076.17 KPI40188.1 - 1.3e-35 120.8 0.2 2.6e-13 49.3 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI40188.1 - 2.1e-31 107.6 0.0 6.1e-11 42.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI40188.1 - 1.2e-16 60.3 0.0 4.6e-06 26.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 KPI40188.1 - 3e-12 45.9 4.6 1.6e-11 43.6 3.2 2.3 1 0 0 1 1 1 1 Putative RRM domain RRM_3 PF08777.6 KPI40188.1 - 8.8e-05 22.2 0.0 0.1 12.4 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 KPI40188.1 - 0.014 15.1 0.0 2.3 8.0 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif NID PF07292.8 KPI40188.1 - 0.016 15.2 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Nmi/IFP 35 domain (NID) Spo7_2_N PF15407.1 KPI40188.1 - 0.028 13.9 0.0 0.36 10.3 0.0 2.5 3 0 0 3 3 3 0 Sporulation protein family 7 DUF4651 PF15513.1 KPI40188.1 - 0.1 12.0 0.0 14 5.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) RNA_pol_3_Rpc31 PF11705.3 KPI40190.1 - 6.5e-28 98.2 35.0 4.2e-26 92.3 24.2 2.1 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Oxidored_FMN PF00724.15 KPI40191.1 - 1.3e-77 261.0 0.0 1.6e-77 260.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FAD_binding_3 PF01494.14 KPI40192.1 - 4e-52 177.4 0.2 3.3e-25 88.8 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain APG12 PF04110.8 KPI40193.1 - 1.4e-25 89.3 0.0 2.6e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF3661 PF12400.3 KPI40194.1 - 2e-42 144.3 3.4 2.9e-42 143.8 2.4 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein DUF3328 PF11807.3 KPI40195.1 - 6.7e-19 68.4 0.1 9.9e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Pacs-1 PF10254.4 KPI40195.1 - 0.0037 15.9 0.2 0.005 15.5 0.1 1.1 1 0 0 1 1 1 1 PACS-1 cytosolic sorting protein Mito_carr PF00153.22 KPI40196.1 - 5.7e-18 64.4 0.1 6.6e-17 60.9 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial carrier protein Ferritin_2 PF13668.1 KPI40197.1 - 0.00049 20.0 0.1 0.0008 19.3 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain Totivirus_coat PF05518.6 KPI40197.1 - 2.6 5.7 10.6 3.9 5.1 7.3 1.2 1 0 0 1 1 1 0 Totivirus coat protein LSM PF01423.17 KPI40198.1 - 1.9e-15 56.1 0.0 2.5e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KPI40198.1 - 5.5e-05 23.0 0.1 8e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2763 PF10961.3 KPI40198.1 - 0.56 10.6 7.6 0.54 10.6 4.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) MFS_1 PF07690.11 KPI40199.1 - 2.4e-41 141.6 45.6 2.4e-41 141.6 31.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI40199.1 - 3.1e-15 55.6 14.9 3.1e-15 55.6 10.3 3.9 1 1 1 3 3 3 1 Sugar (and other) transporter ATP1G1_PLM_MAT8 PF02038.11 KPI40199.1 - 4.6 6.3 6.9 3.5 6.6 0.2 2.7 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Fungal_trans PF04082.13 KPI40200.1 - 4.1e-10 38.9 0.0 6.8e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nucleopor_Nup85 PF07575.8 KPI40201.1 - 0.016 13.4 0.0 0.02 13.0 0.0 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin DUF1986 PF09342.6 KPI40202.1 - 0.0061 15.8 0.1 0.0064 15.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF4407 PF14362.1 KPI40202.1 - 0.12 11.3 0.1 0.12 11.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.1 KPI40202.1 - 0.82 9.6 4.6 1.3 9.0 3.2 1.4 1 1 0 1 1 1 0 FlxA-like protein Aldo_ket_red PF00248.16 KPI40203.1 - 3.5e-65 219.6 0.0 4.3e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Prok-RING_2 PF14445.1 KPI40204.1 - 0.0045 16.9 2.3 0.009 15.9 1.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 2 C1_3 PF07649.7 KPI40204.1 - 0.78 9.8 6.0 1.2 9.2 4.2 1.3 1 0 0 1 1 1 0 C1-like domain Nop14 PF04147.7 KPI40204.1 - 1.2 6.9 9.9 1.6 6.5 6.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 KPI40204.1 - 6 6.0 13.3 1.8 7.7 7.2 1.6 2 0 0 2 2 2 0 SDA1 PBP1_TM PF14812.1 KPI40204.1 - 8 6.8 8.9 13 6.2 4.6 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2011 PF09428.5 KPI40205.1 - 1.5e-17 63.7 6.1 4.3e-17 62.2 4.2 1.7 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) PAT1 PF09770.4 KPI40205.1 - 0.0023 16.2 3.2 0.0027 16.0 2.2 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUSP PF06337.7 KPI40206.1 - 3e-14 53.2 0.0 1.8e-13 50.6 0.0 2.2 2 0 0 2 2 2 1 DUSP domain Rpr2 PF04032.11 KPI40207.1 - 0.52 10.2 4.0 15 5.4 0.0 3.2 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_4 PF13894.1 KPI40207.1 - 1.4 9.4 23.2 3.7 8.1 0.1 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger zf-met PF12874.2 KPI40207.1 - 1.9 8.7 10.9 0.49 10.6 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KPI40207.1 - 3.6 7.8 5.7 18 5.6 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HEAT PF02985.17 KPI40208.1 - 5.3e-21 72.7 8.9 0.00015 21.5 0.1 8.5 8 0 0 8 8 8 4 HEAT repeat HEAT_EZ PF13513.1 KPI40208.1 - 4.5e-20 71.5 13.4 1e-06 29.0 0.1 10.0 10 2 2 12 12 11 4 HEAT-like repeat HEAT_2 PF13646.1 KPI40208.1 - 1.1e-15 57.6 15.9 5.5e-05 23.3 0.5 7.0 6 1 1 7 7 7 3 HEAT repeats Vac14_Fab1_bd PF12755.2 KPI40208.1 - 1.5e-09 38.1 1.6 2.1 8.8 0.0 6.5 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 KPI40208.1 - 3.2e-09 36.5 3.7 3.5e-05 23.6 0.7 5.6 6 0 0 6 6 6 1 Importin-beta N-terminal domain CLASP_N PF12348.3 KPI40208.1 - 1.8e-08 34.0 1.2 0.015 14.6 0.0 4.6 4 1 1 5 5 5 2 CLASP N terminal Cnd1 PF12717.2 KPI40208.1 - 1.7e-06 28.0 8.2 0.19 11.5 0.5 5.2 5 0 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 KPI40208.1 - 1.9e-06 27.4 8.7 1.5 8.7 0.1 5.9 7 0 0 7 7 6 3 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 KPI40208.1 - 6.9e-06 25.9 2.5 0.00088 19.1 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion UME PF08064.8 KPI40208.1 - 0.00017 21.5 0.0 6.6 6.7 0.0 5.4 3 2 3 6 6 6 1 UME (NUC010) domain MMS19_C PF12460.3 KPI40208.1 - 0.00048 18.9 7.7 0.0049 15.6 0.0 4.3 5 0 0 5 5 5 1 RNAPII transcription regulator C-terminal DUF2435 PF10363.4 KPI40208.1 - 0.0009 19.0 2.9 1.6 8.7 0.1 4.9 5 0 0 5 5 4 1 Protein of unknown function (DUF2435) DUF4042 PF13251.1 KPI40208.1 - 0.086 12.2 3.8 7.5 5.9 0.0 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4042) Amino_oxidase PF01593.19 KPI40209.1 - 2.5e-20 72.9 0.0 2.8e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KPI40209.1 - 3.4e-16 59.0 0.1 5.2e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI40209.1 - 2.6e-08 33.1 1.5 3.6e-08 32.6 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KPI40209.1 - 8.9e-08 32.4 0.2 1.7e-07 31.5 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI40209.1 - 3e-07 30.7 0.0 3.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI40209.1 - 6e-07 28.6 0.2 6.8e-07 28.5 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KPI40209.1 - 1.9e-06 26.6 1.2 2.8e-06 26.0 0.8 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KPI40209.1 - 3.7e-06 26.1 0.2 5.3e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KPI40209.1 - 1e-05 24.8 0.1 1e-05 24.8 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KPI40209.1 - 4.8e-05 22.5 0.9 7.1e-05 22.0 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KPI40209.1 - 9e-05 22.4 0.5 0.00012 21.9 0.3 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI40209.1 - 0.00052 18.9 0.5 0.00068 18.6 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KPI40209.1 - 0.0067 15.3 0.4 0.009 14.9 0.2 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KPI40209.1 - 0.013 15.3 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KPI40209.1 - 0.02 14.8 0.2 0.03 14.3 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 KPI40209.1 - 0.056 13.0 0.2 0.086 12.4 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Rossmann-like PF10727.4 KPI40209.1 - 0.088 12.5 0.2 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 Rossmann-like domain Strep_67kDa_ant PF06100.6 KPI40209.1 - 0.15 10.4 0.1 0.19 10.0 0.1 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family FAD_binding_3 PF01494.14 KPI40211.1 - 1.8e-28 99.6 0.1 5.5e-28 98.0 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KPI40211.1 - 1.1e-06 28.4 0.4 0.022 14.5 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KPI40211.1 - 0.00015 20.8 1.5 0.27 10.1 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 KPI40211.1 - 0.00082 18.3 0.2 0.069 12.0 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI40211.1 - 0.001 19.0 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KPI40211.1 - 0.01 16.1 0.6 3.3 8.1 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI40211.1 - 0.011 15.8 0.0 0.027 14.5 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KPI40211.1 - 0.054 12.1 0.1 16 4.0 0.0 2.9 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 KPI40211.1 - 0.063 13.1 0.1 0.75 9.6 0.1 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SNF2_N PF00176.18 KPI40212.1 - 7e-12 44.7 0.2 4.5e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 KPI40212.1 - 1.9e-10 40.3 0.0 3.4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase zf-RING_5 PF14634.1 KPI40212.1 - 0.084 12.6 16.0 0.67 9.7 0.7 2.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KPI40212.1 - 0.88 9.6 17.0 3.4 7.7 1.4 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KPI40212.1 - 0.99 9.0 9.6 0.21 11.1 0.8 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 MFS_1 PF07690.11 KPI40213.1 - 1.7e-22 79.6 55.3 4.1e-18 65.2 30.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Patched PF02460.13 KPI40214.1 - 5.9e-71 239.5 16.3 5.9e-71 239.5 11.3 2.6 2 1 0 2 2 2 1 Patched family Sterol-sensing PF12349.3 KPI40214.1 - 7.7e-50 168.3 7.0 7.7e-50 168.3 4.8 3.3 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 KPI40214.1 - 5.1e-05 22.1 8.5 5.1e-05 22.1 5.9 2.9 2 1 0 2 2 2 1 MMPL family ACR_tran PF00873.14 KPI40214.1 - 0.32 8.3 15.7 0.0051 14.2 5.2 1.9 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family HAD PF12710.2 KPI40216.1 - 4.5e-18 66.1 0.1 1.1e-17 64.8 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KPI40216.1 - 2.7e-17 62.5 0.1 5.7e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KPI40216.1 - 4.6e-13 48.9 0.0 1.2e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KPI40216.1 - 7.2e-13 49.4 0.1 4.8e-12 46.7 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KPI40216.1 - 0.0046 16.5 0.1 0.019 14.5 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KPI40216.1 - 0.036 14.2 0.2 0.19 11.9 0.0 2.3 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 KPI40218.1 - 0.01 15.7 0.4 0.8 9.6 0.1 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat Nup54 PF13874.1 KPI40218.1 - 0.013 15.1 6.0 0.036 13.7 4.0 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 AATF-Che1 PF13339.1 KPI40218.1 - 0.027 14.6 3.4 0.23 11.5 1.6 2.5 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF4559 PF15112.1 KPI40218.1 - 0.061 12.4 0.8 0.11 11.6 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF1319 PF07028.6 KPI40218.1 - 0.58 10.3 7.2 2.9 8.0 2.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) Atg14 PF10186.4 KPI40218.1 - 1.1 8.1 15.0 0.16 10.9 6.5 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DJ-1_PfpI PF01965.19 KPI40219.1 - 6.8e-09 35.3 0.0 4.1e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KPI40219.1 - 0.042 13.1 0.0 0.095 11.9 0.0 1.6 1 1 0 1 1 1 0 Putative amidotransferase DUF3295 PF11702.3 KPI40220.1 - 2.2e-91 307.4 39.6 2.7e-91 307.1 27.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KPI40220.1 - 1.9e-11 43.3 1.7 4.4e-11 42.1 1.2 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Ribosomal_S16 PF00886.14 KPI40221.1 - 4.7e-22 77.4 0.0 7.4e-22 76.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 RRM_1 PF00076.17 KPI40222.1 - 4.7e-36 122.2 0.3 2.7e-17 62.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI40222.1 - 1.5e-30 104.9 0.1 1.5e-15 56.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI40222.1 - 1.9e-14 53.2 0.2 1.9e-07 30.8 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med3 PF11593.3 KPI40222.1 - 0.00018 20.8 19.4 0.00018 20.8 13.5 2.0 3 0 0 3 3 3 1 Mediator complex subunit 3 fungal PAT1 PF09770.4 KPI40222.1 - 3.2 5.8 29.4 7.2 4.7 20.4 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sdh5 PF03937.11 KPI40223.1 - 1.4e-22 79.1 0.7 4e-22 77.6 0.2 1.8 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase DEAD PF00270.24 KPI40225.1 - 5.9e-41 139.7 0.0 1.2e-40 138.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI40225.1 - 5e-26 90.3 0.0 1.3e-25 89.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KPI40225.1 - 9.8e-05 21.2 0.0 0.00014 20.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KPI40225.1 - 0.0066 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit BTB PF00651.26 KPI40226.1 - 4e-10 39.6 0.0 2.1e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain DNA_RNApol_7kD PF03604.8 KPI40226.1 - 8 6.0 12.0 9.3 5.8 0.1 3.5 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit NmrA PF05368.8 KPI40227.1 - 2.2e-27 95.8 0.1 2.2e-26 92.5 0.1 2.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI40227.1 - 1.6e-09 38.0 0.3 2.4e-09 37.4 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KPI40227.1 - 0.0049 16.8 0.3 0.01 15.7 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Inp1 PF12634.2 KPI40228.1 - 1.1e-35 122.4 0.0 3.8e-35 120.6 0.0 2.0 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 F-box-like PF12937.2 KPI40229.1 - 3.8e-06 26.5 0.5 0.15 11.8 0.0 3.1 2 1 0 2 2 2 2 F-box-like F-box PF00646.28 KPI40229.1 - 0.0088 15.6 2.3 1.1 8.9 0.0 3.4 3 0 0 3 3 3 2 F-box domain ATP-synt_B PF00430.13 KPI40230.1 - 3.9 7.2 10.7 4.1 7.1 7.4 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF2992 PF11208.3 KPI40230.1 - 4.6 7.1 18.9 4.5 7.1 13.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) CAF-1_p150 PF11600.3 KPI40230.1 - 7.7 5.8 22.6 8.6 5.6 15.7 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal HET PF06985.6 KPI40231.1 - 2e-25 89.5 0.2 3.3e-25 88.8 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NmrA PF05368.8 KPI40232.1 - 1.9e-47 161.5 0.1 2.3e-47 161.2 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI40232.1 - 1.5e-10 41.3 0.0 2.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KPI40232.1 - 3.3e-05 22.7 0.1 4.9e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 KPI40233.1 - 1.3e-12 47.1 56.0 5.5e-08 31.8 29.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 KPI40234.1 - 9.6e-30 104.1 0.1 1.2e-29 103.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI40234.1 - 3e-18 66.2 0.1 3.7e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI40234.1 - 2.7e-13 49.8 0.0 6e-13 48.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KPI40234.1 - 1.4e-12 47.2 0.0 3.7e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 KPI40234.1 - 2.8e-05 23.5 0.1 0.00021 20.6 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KPI40234.1 - 0.0001 21.5 0.1 0.0015 17.7 0.0 2.6 3 0 0 3 3 3 1 Prolyl oligopeptidase family DUF1057 PF06342.7 KPI40234.1 - 0.00013 20.8 0.3 0.0006 18.7 0.0 2.0 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF1057) Chlorophyllase2 PF12740.2 KPI40234.1 - 0.00065 18.6 0.1 0.0012 17.7 0.1 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.15 KPI40234.1 - 0.00071 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.6 KPI40234.1 - 0.0016 17.3 0.1 0.0047 15.7 0.1 1.6 1 1 0 1 1 1 1 Chlorophyllase Thioesterase PF00975.15 KPI40234.1 - 0.0046 17.1 0.2 0.011 15.9 0.1 1.6 1 1 0 1 1 1 1 Thioesterase domain DUF676 PF05057.9 KPI40234.1 - 0.0067 15.7 0.0 0.016 14.4 0.0 1.7 1 1 1 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KPI40234.1 - 0.016 14.8 0.2 0.045 13.3 0.1 1.8 1 1 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 KPI40234.1 - 0.046 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 KPI40234.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.6 KPI40234.1 - 0.14 11.8 0.6 2.4 7.8 0.0 2.7 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Ank_5 PF13857.1 KPI40236.1 - 2.2e-06 27.6 0.0 6.7e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI40236.1 - 0.00011 22.1 0.0 0.00043 20.2 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 KPI40236.1 - 0.00046 19.8 0.0 0.0015 18.2 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 KPI40236.1 - 0.00046 20.4 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KPI40236.1 - 0.0019 18.6 0.1 0.15 12.6 0.0 2.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF489 PF04356.7 KPI40236.1 - 0.0061 16.1 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF489) adh_short PF00106.20 KPI40237.1 - 4.7e-20 72.1 0.0 8.4e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI40237.1 - 0.00083 19.0 0.0 0.0028 17.3 0.0 1.8 1 1 0 1 1 1 1 KR domain Ecm33 PF12454.3 KPI40238.1 - 0.061 13.2 0.9 8.4 6.3 0.1 3.2 3 0 0 3 3 3 0 GPI-anchored cell wall organization protein Sugar_tr PF00083.19 KPI40239.1 - 5.6e-75 252.6 32.2 6.3e-75 252.4 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI40239.1 - 3e-22 78.8 45.5 1e-15 57.3 13.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3753 PF12575.3 KPI40239.1 - 0.082 12.7 2.1 0.28 11.0 1.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) HTH_20 PF12840.2 KPI40239.1 - 0.084 12.6 0.0 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1648 PF07853.6 KPI40239.1 - 0.09 12.2 3.6 0.4 10.2 2.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1648) Clat_adaptor_s PF01217.15 KPI40240.1 - 1.9e-50 170.2 4.7 2.2e-49 166.8 3.2 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain DEAD PF00270.24 KPI40242.1 - 2.7e-33 114.8 0.0 9.6e-32 109.7 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KPI40242.1 - 1.4e-20 72.6 0.0 2.7e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KPI40242.1 - 3.5e-17 62.0 0.0 7.1e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI40242.1 - 0.00057 19.7 0.0 0.0039 17.0 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KPI40242.1 - 0.073 12.8 0.0 0.28 10.9 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Sugar_tr PF00083.19 KPI40243.1 - 2.9e-65 220.6 28.2 9.8e-43 146.3 1.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter DUF1365 PF07103.6 KPI40243.1 - 1.1e-41 142.6 0.0 1.7e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) MFS_1 PF07690.11 KPI40243.1 - 1.8e-22 79.5 39.7 3.4e-16 58.9 7.7 2.6 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3377 PF11857.3 KPI40243.1 - 0.042 13.4 2.8 3.9 7.1 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) ABC_tran PF00005.22 KPI40246.1 - 4.5e-51 172.7 0.4 4.7e-25 88.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 KPI40246.1 - 6.1e-45 152.9 44.5 3.7e-24 85.0 14.3 2.3 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.1 KPI40246.1 - 1.5e-18 67.7 0.4 2.4e-05 24.4 0.1 4.3 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.1 KPI40246.1 - 4.9e-11 42.9 2.7 0.00014 21.9 0.1 2.9 3 0 0 3 3 2 2 AAA ATPase domain SMC_N PF02463.14 KPI40246.1 - 2e-10 40.2 2.3 2.5e-05 23.6 0.1 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KPI40246.1 - 2.8e-10 39.6 1.1 0.00016 20.8 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KPI40246.1 - 7e-10 38.6 0.1 0.0043 16.4 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KPI40246.1 - 1.8e-09 36.9 2.5 0.00035 20.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KPI40246.1 - 2.1e-09 37.9 0.3 0.0014 19.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KPI40246.1 - 5.9e-08 32.9 0.1 0.019 15.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KPI40246.1 - 8.6e-08 32.1 0.1 0.0046 16.6 0.0 2.8 2 1 1 3 3 3 2 Archaeal ATPase AAA_17 PF13207.1 KPI40246.1 - 1.3e-07 32.4 0.0 0.0037 18.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KPI40246.1 - 1.7e-07 30.6 0.0 0.17 10.8 0.0 3.7 4 0 0 4 4 4 2 AAA ATPase domain cobW PF02492.14 KPI40246.1 - 4.2e-06 26.3 1.4 0.011 15.2 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KPI40246.1 - 4.4e-06 26.8 0.1 0.22 11.6 0.0 3.1 3 0 0 3 3 3 2 RNA helicase NACHT PF05729.7 KPI40246.1 - 4.6e-06 26.3 0.1 0.084 12.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.1 KPI40246.1 - 5.6e-06 26.3 0.3 0.13 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KPI40246.1 - 2e-05 24.9 0.1 0.092 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KPI40246.1 - 2.1e-05 24.4 0.1 0.26 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KPI40246.1 - 2.2e-05 24.3 2.0 0.046 13.6 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KPI40246.1 - 2.6e-05 24.7 0.3 0.14 12.6 0.1 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 KPI40246.1 - 3.1e-05 23.5 2.1 0.063 12.6 0.1 2.7 3 0 0 3 3 3 2 AAA-like domain MobB PF03205.9 KPI40246.1 - 3.8e-05 23.4 0.4 0.22 11.2 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KPI40246.1 - 4.6e-05 23.0 1.0 0.016 14.7 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.1 KPI40246.1 - 6.2e-05 22.6 4.1 0.056 13.1 0.0 3.4 3 1 0 3 3 2 2 Part of AAA domain AAA_30 PF13604.1 KPI40246.1 - 0.00011 21.8 0.5 0.23 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KPI40246.1 - 0.00024 21.3 0.3 1.3 9.2 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KPI40246.1 - 0.00056 19.0 0.6 0.38 9.8 0.1 2.3 2 0 0 2 2 2 2 Zeta toxin T2SE PF00437.15 KPI40246.1 - 0.00064 18.7 0.9 0.64 8.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_5 PF07728.9 KPI40246.1 - 0.00091 18.9 0.4 1.1 8.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 KPI40246.1 - 0.001 18.0 0.5 0.48 9.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF2075 PF09848.4 KPI40246.1 - 0.0013 17.8 0.1 0.92 8.4 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 KPI40246.1 - 0.003 17.2 1.0 3.8 7.1 0.1 3.3 3 0 0 3 3 3 0 NTPase PRK PF00485.13 KPI40246.1 - 0.0036 16.8 0.7 0.82 9.1 0.1 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family ABC_ATPase PF09818.4 KPI40246.1 - 0.0039 15.8 0.2 0.37 9.3 0.0 2.5 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_14 PF13173.1 KPI40246.1 - 0.0058 16.5 0.1 5.4 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KPI40246.1 - 0.01 15.6 2.0 2.2 8.0 0.0 2.7 3 0 0 3 3 2 0 Dynamin family AAA_35 PF14516.1 KPI40246.1 - 0.01 14.4 0.2 1.1 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 KPI40246.1 - 0.011 15.4 0.3 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 KPI40246.1 - 0.016 14.7 0.3 3.3 7.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KPI40246.1 - 0.017 15.0 0.3 0.7 9.8 0.0 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 KPI40246.1 - 0.022 14.2 0.6 3.2 7.2 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 KPI40246.1 - 0.026 13.4 0.0 1 8.2 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain ABC2_membrane_3 PF12698.2 KPI40246.1 - 0.032 13.2 36.9 0.31 10.0 8.6 3.4 3 0 0 3 3 3 0 ABC-2 family transporter protein IstB_IS21 PF01695.12 KPI40246.1 - 0.042 13.2 1.2 3.6 6.9 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 KPI40246.1 - 0.043 13.3 0.8 5.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA12 PF10443.4 KPI40246.1 - 0.062 11.7 0.2 1.9 6.9 0.0 2.3 2 0 0 2 2 2 0 RNA12 protein PIF1 PF05970.9 KPI40246.1 - 0.064 12.1 0.1 4.8 6.0 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase Bac_DnaA PF00308.13 KPI40246.1 - 0.079 12.5 0.0 15 5.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein Gtr1_RagA PF04670.7 KPI40246.1 - 0.12 11.5 1.2 9.5 5.2 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_11 PF13086.1 KPI40246.1 - 0.12 11.9 0.1 11 5.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 KPI40246.1 - 0.14 11.3 0.4 9.3 5.4 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Guanylate_kin PF00625.16 KPI40246.1 - 0.14 11.5 0.1 4.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase Septin PF00735.13 KPI40246.1 - 0.14 11.1 0.4 7.3 5.5 0.0 2.2 2 0 0 2 2 2 0 Septin APS_kinase PF01583.15 KPI40246.1 - 0.16 11.6 1.2 5.7 6.5 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.17 KPI40246.1 - 0.23 10.3 0.1 4.2 6.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain SRP54 PF00448.17 KPI40246.1 - 0.46 9.8 2.4 2.5 7.4 0.2 2.4 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_13 PF13166.1 KPI40246.1 - 1.2 7.4 0.9 7.2 4.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain Glyco_hydro_31 PF01055.21 KPI40247.1 - 1.3e-84 284.6 0.0 1.6e-84 284.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KPI40247.1 - 1.3e-13 50.5 0.0 4e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like F-box-like PF12937.2 KPI40249.1 - 0.049 13.3 0.3 0.13 11.9 0.2 1.8 1 0 0 1 1 1 0 F-box-like DUF2237 PF09996.4 KPI40250.1 - 3.3e-16 58.8 0.1 2e-15 56.3 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) adh_short PF00106.20 KPI40251.1 - 1e-18 67.7 0.1 1.8e-18 67.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI40251.1 - 5.5e-10 39.2 0.1 7.6e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI40251.1 - 1.1e-07 31.8 0.0 1.5e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KPI40251.1 - 0.00051 19.7 0.3 0.0013 18.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KPI40251.1 - 0.031 13.1 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 KPI40251.1 - 0.082 12.3 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KPI40251.1 - 0.095 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ovate PF04844.8 KPI40252.1 - 0.088 12.6 0.0 1.2 8.9 0.0 2.6 3 0 0 3 3 3 0 Transcriptional repressor, ovate adh_short PF00106.20 KPI40253.1 - 9.6e-08 32.1 0.0 1.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI40253.1 - 0.002 17.9 0.1 0.0024 17.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KPI40253.1 - 0.0039 17.2 0.1 0.0068 16.4 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KPI40253.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.13 KPI40253.1 - 0.064 12.8 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KPI40253.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.11 KPI40255.1 - 6.1e-36 123.8 27.1 6.1e-36 123.8 18.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily SPC12 PF06645.8 KPI40255.1 - 3.5 7.4 5.8 14 5.6 0.0 3.7 3 1 1 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.11 KPI40256.1 - 5.1e-24 84.6 56.5 3e-18 65.6 17.0 3.6 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF3784 PF12650.2 KPI40256.1 - 1.9 8.5 5.0 1.1e+02 2.7 0.0 4.2 4 1 1 5 5 5 0 Domain of unknown function (DUF3784) DUF3287 PF11690.3 KPI40257.1 - 0.027 14.5 4.8 0.063 13.3 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Ald_Xan_dh_C2 PF02738.13 KPI40257.1 - 0.032 12.5 1.2 0.052 11.8 0.8 1.3 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase GCS PF03074.11 KPI40257.1 - 0.14 11.1 2.0 0.13 11.2 0.3 1.7 2 0 0 2 2 2 0 Glutamate-cysteine ligase SPAM PF02090.10 KPI40257.1 - 0.31 11.0 8.8 0.57 10.1 6.1 1.4 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein Cauli_AT PF03233.8 KPI40257.1 - 1.8 8.2 10.1 1.5 8.5 5.4 2.0 1 1 0 2 2 2 0 Aphid transmission protein Nbs1_C PF08599.5 KPI40257.1 - 4.6 7.2 6.2 0.51 10.3 0.6 2.2 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 AMP-binding PF00501.23 KPI40258.1 - 3.2e-90 302.4 0.0 3.8e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI40258.1 - 4.8e-12 46.6 0.0 1.5e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PALP PF00291.20 KPI40259.1 - 4.6e-64 216.5 0.0 7.8e-64 215.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4597 PF15366.1 KPI40259.1 - 0.049 13.2 0.1 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Chitin_synth_1 PF01644.12 KPI40260.1 - 1.1e-68 230.1 0.0 1.6e-68 229.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KPI40260.1 - 2e-28 99.0 1.3 3.7e-21 75.1 0.0 2.5 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.6 KPI40260.1 - 4.5e-28 96.7 0.0 8.7e-28 95.8 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 KPI40260.1 - 1.1e-12 48.0 0.3 1.1e-12 48.0 0.2 2.7 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KPI40260.1 - 7.7e-09 35.6 0.0 2.5e-08 34.0 0.0 2.0 2 1 0 2 2 2 1 Glycosyltransferase like family 2 zf-C2H2 PF00096.21 KPI40262.1 - 4.2e-06 26.7 10.7 0.011 15.9 2.6 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI40262.1 - 1.1e-05 25.4 10.7 0.0058 16.8 3.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KPI40262.1 - 0.0025 18.0 10.0 0.0042 17.3 0.3 2.8 3 0 0 3 3 2 1 Zinc-finger double domain Spc7 PF08317.6 KPI40262.1 - 0.0032 16.1 6.6 0.0044 15.7 4.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF883 PF05957.8 KPI40262.1 - 0.0048 17.2 1.6 0.011 16.1 1.1 1.6 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) GAS PF13851.1 KPI40262.1 - 0.0056 15.8 9.2 0.0079 15.4 6.4 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding zf-met PF12874.2 KPI40262.1 - 0.0063 16.6 3.8 0.099 12.8 0.3 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KPI40262.1 - 0.022 14.8 5.0 0.061 13.4 1.0 2.4 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KPI40262.1 - 0.027 14.5 3.6 0.046 13.8 2.5 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding AAA_27 PF13514.1 KPI40262.1 - 0.056 11.1 7.4 0.079 10.6 5.1 1.1 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 KPI40262.1 - 0.062 12.8 12.2 0.093 12.3 8.5 1.2 1 0 0 1 1 1 0 IncA protein Rubredoxin PF00301.15 KPI40262.1 - 0.075 12.9 0.8 2.7 7.9 0.1 2.7 2 0 0 2 2 2 0 Rubredoxin XRCC4 PF06632.7 KPI40262.1 - 0.093 11.5 1.2 0.18 10.6 0.9 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 APG6 PF04111.7 KPI40262.1 - 0.11 11.5 10.8 0.16 10.9 7.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_1 PF00170.16 KPI40262.1 - 0.12 12.3 4.7 1.2 9.1 0.4 2.7 1 1 0 2 2 2 0 bZIP transcription factor Cep57_MT_bd PF06657.8 KPI40262.1 - 0.21 11.5 4.7 0.13 12.1 1.2 2.1 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ADIP PF11559.3 KPI40262.1 - 0.22 11.3 14.7 2.3 8.1 10.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.6 KPI40262.1 - 0.26 11.0 9.8 0.8 9.4 1.5 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TMF_TATA_bd PF12325.3 KPI40262.1 - 0.29 10.8 8.4 0.9 9.2 5.9 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding HALZ PF02183.13 KPI40262.1 - 0.33 10.6 11.9 0.2 11.3 0.7 3.4 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF342 PF03961.8 KPI40262.1 - 0.35 9.2 5.0 0.48 8.7 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) GrpE PF01025.14 KPI40262.1 - 0.66 9.5 10.6 3.9 6.9 7.0 2.3 2 1 0 2 2 2 0 GrpE CENP-F_leu_zip PF10473.4 KPI40262.1 - 0.68 9.7 10.2 2.2 8.1 7.1 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snf7 PF03357.16 KPI40262.1 - 0.91 8.8 10.5 1.4 8.2 7.3 1.2 1 0 0 1 1 1 0 Snf7 DivIC PF04977.10 KPI40262.1 - 1.2 8.7 15.8 0.09 12.2 3.2 2.2 1 1 1 2 2 2 0 Septum formation initiator Zn-ribbon_8 PF09723.5 KPI40262.1 - 1.2 9.1 5.4 8.8 6.3 2.4 2.8 2 1 0 2 2 2 0 Zinc ribbon domain CCDC155 PF14662.1 KPI40262.1 - 1.2 8.6 12.7 1.8 8.1 8.8 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF4201 PF13870.1 KPI40262.1 - 1.3 8.3 8.9 2.5 7.5 6.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Phage_GPO PF05929.6 KPI40262.1 - 1.4 8.1 5.1 2 7.5 3.5 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase ATG16 PF08614.6 KPI40262.1 - 1.8 8.3 12.3 2.1 8.1 1.6 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Ax_dynein_light PF10211.4 KPI40262.1 - 2.4 7.9 10.7 1.2 8.9 3.7 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain DUF2205 PF10224.4 KPI40262.1 - 2.6 7.6 6.5 2.6 7.6 0.6 2.3 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 KPI40262.1 - 2.7 8.3 8.8 54 4.1 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 KPI40262.1 - 2.8 7.5 7.3 5.7 6.5 5.1 1.5 1 0 0 1 1 1 0 Mnd1 family DUF3450 PF11932.3 KPI40262.1 - 4.2 6.5 15.6 2.6 7.2 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) bZIP_Maf PF03131.12 KPI40262.1 - 4.5 7.6 12.0 4.9 7.5 1.4 2.6 1 1 0 2 2 2 0 bZIP Maf transcription factor V_ATPase_I PF01496.14 KPI40262.1 - 4.5 5.0 5.0 5.6 4.6 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WXG100 PF06013.7 KPI40262.1 - 4.7 7.2 9.2 1.7 8.6 0.7 2.4 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Seryl_tRNA_N PF02403.17 KPI40262.1 - 5.5 7.0 9.5 38 4.3 6.6 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FUSC PF04632.7 KPI40262.1 - 5.5 5.2 7.6 8.4 4.6 5.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Rab5-bind PF09311.6 KPI40262.1 - 5.9 6.7 16.4 2.4e+02 1.5 11.3 2.3 1 1 0 1 1 1 0 Rabaptin-like protein UPF0242 PF06785.6 KPI40262.1 - 6.5 5.3 7.1 18 3.8 4.9 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) HlyD PF00529.15 KPI40262.1 - 6.9 5.8 15.3 10 5.3 10.6 1.2 1 0 0 1 1 1 0 HlyD family secretion protein MFS_1 PF07690.11 KPI40263.1 - 7.9e-41 139.9 33.7 7.9e-41 139.9 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KPI40263.1 - 9.1e-06 23.9 7.3 0.028 12.4 1.2 3.5 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MRP-S28 PF10213.4 KPI40264.1 - 2.3e-38 131.1 0.2 4.3e-38 130.2 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein zf-C2H2 PF00096.21 KPI40268.1 - 8.4e-09 35.2 6.7 0.0013 18.9 0.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 KPI40268.1 - 3e-07 29.6 0.1 7.4e-07 28.3 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KPI40268.1 - 8.5e-07 28.8 7.3 0.002 18.3 1.1 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KPI40268.1 - 1.1e-05 25.4 0.3 1.1e-05 25.4 0.2 3.3 3 0 0 3 3 3 1 Zinc-finger double domain GAGA PF09237.6 KPI40268.1 - 4.5e-05 22.9 3.9 0.064 12.8 0.6 2.5 1 1 1 2 2 2 2 GAGA factor zf-C2H2_jaz PF12171.3 KPI40268.1 - 0.015 15.3 0.4 1.8 8.7 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KPI40268.1 - 0.038 14.2 1.0 3.2 8.1 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Crust_neurohorm PF01147.12 KPI40268.1 - 0.085 12.1 0.1 0.085 12.1 0.0 2.1 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family Homeobox_KN PF05920.6 KPI40270.1 - 1.9e-05 24.2 0.0 5.4e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain zf-met PF12874.2 KPI40270.1 - 2.9e-05 24.1 0.2 0.15 12.3 0.0 4.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KPI40270.1 - 5.6e-05 23.2 0.6 5.6e-05 23.2 0.4 4.9 5 0 0 5 5 5 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI40270.1 - 0.00037 20.6 1.0 0.00037 20.6 0.7 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger Homeobox PF00046.24 KPI40270.1 - 0.0012 18.4 0.5 0.0012 18.4 0.4 1.9 2 0 0 2 2 2 1 Homeobox domain zf-Di19 PF05605.7 KPI40270.1 - 0.018 15.1 3.8 1.7 8.8 2.6 2.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KPI40270.1 - 0.19 11.8 1.6 0.58 10.3 0.0 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KPI40270.1 - 3.4 8.1 10.8 2.8 8.3 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger double domain NmrA PF05368.8 KPI40271.1 - 7.8e-06 25.3 0.0 8.6e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI40271.1 - 0.00067 19.7 0.0 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NESP55 PF06390.7 KPI40272.1 - 1.4 8.2 9.6 4 6.7 6.6 1.8 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) PhyH PF05721.8 KPI40273.1 - 1.6e-54 185.1 0.0 2e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pkinase PF00069.20 KPI40274.1 - 1.8e-70 237.0 0.0 2.4e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI40274.1 - 1.7e-35 122.3 0.0 2.5e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI40274.1 - 3.3e-07 29.5 0.0 9.6e-07 28.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KPI40274.1 - 2.8e-05 23.2 0.0 4.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KPI40274.1 - 0.0012 18.5 0.0 0.003 17.3 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KPI40274.1 - 0.0034 16.7 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Peptidase_M14 PF00246.19 KPI40275.1 - 1.6e-15 57.5 0.0 2.4e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase MBOAT_2 PF13813.1 KPI40275.1 - 2e-13 50.2 1.9 4.6e-13 49.0 1.3 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family AstE_AspA PF04952.9 KPI40275.1 - 0.041 12.7 0.0 0.084 11.7 0.0 1.5 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.3 KPI40275.1 - 0.06 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) DNA_primase_lrg PF04104.9 KPI40275.1 - 0.37 10.0 0.0 0.57 9.3 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit Cation_efflux PF01545.16 KPI40276.1 - 6.9e-50 169.7 9.9 1.2e-49 168.9 6.9 1.3 1 0 0 1 1 1 1 Cation efflux family NicO PF03824.11 KPI40276.1 - 2.4e-05 23.7 7.6 2.4e-05 23.7 5.3 3.0 3 0 0 3 3 3 2 High-affinity nickel-transport protein Zip PF02535.17 KPI40276.1 - 0.003 16.6 25.1 0.003 16.6 17.4 3.3 1 1 2 3 3 3 1 ZIP Zinc transporter AIG2 PF06094.7 KPI40277.1 - 0.00044 20.6 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 AIG2-like family zf-RING_2 PF13639.1 KPI40278.1 - 1.7e-06 27.7 9.0 6.4e-06 25.8 3.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KPI40278.1 - 0.0002 21.3 5.8 0.00052 20.0 4.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KPI40278.1 - 0.00048 19.7 3.3 0.001 18.6 1.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI40278.1 - 0.002 18.0 8.3 0.004 17.1 2.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Abhydrolase_6 PF12697.2 KPI40279.1 - 7e-13 48.9 0.2 9.3e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI40279.1 - 0.00078 19.2 0.0 0.0012 18.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI40279.1 - 0.072 12.6 0.1 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold AMP-binding PF00501.23 KPI40281.1 - 2.4e-75 253.5 2.9 6.1e-62 209.3 0.2 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 KPI40281.1 - 3.5e-12 47.0 0.1 7.5e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hydrolase PF00702.21 KPI40281.1 - 0.085 13.2 0.2 15 5.8 0.0 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase EI24 PF07264.6 KPI40282.1 - 6.5e-08 32.2 5.2 1.9e-06 27.4 3.6 2.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2628 PF10947.3 KPI40282.1 - 0.16 11.7 2.0 0.26 11.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) PhyH PF05721.8 KPI40284.1 - 1.4e-09 38.3 0.0 1.9e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2803 PF10972.3 KPI40287.1 - 0.067 12.6 0.0 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2803) RabGAP-TBC PF00566.13 KPI40288.1 - 1.3e-47 162.0 0.0 2.5e-47 161.1 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ApoLp-III PF07464.6 KPI40288.1 - 0.038 14.0 3.5 0.084 12.9 0.2 2.7 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) IlvN PF07991.7 KPI40289.1 - 5.8e-46 155.8 0.0 8.5e-46 155.3 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 KPI40289.1 - 3.5e-44 150.2 0.0 5e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 KPI40289.1 - 0.045 14.1 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Toxin_18 PF08087.6 KPI40291.1 - 1.7 8.4 5.3 0.57 10.0 0.2 2.5 2 0 0 2 2 2 0 Conotoxin O-superfamily adh_short PF00106.20 KPI40292.1 - 1.8e-06 28.0 0.1 3.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI40292.1 - 0.00024 20.8 0.0 0.0004 20.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Glyco_hydro_3 PF00933.16 KPI40293.1 - 6.6e-79 265.0 0.0 9.2e-79 264.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KPI40293.1 - 3.3e-48 164.1 0.1 6.2e-47 160.0 0.0 2.5 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KPI40293.1 - 1e-17 63.8 0.0 1.9e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF1675 PF07897.6 KPI40294.1 - 0.85 9.4 8.8 0.99 9.2 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Methyltransf_31 PF13847.1 KPI40295.1 - 2.3e-29 101.9 0.0 3.3e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI40295.1 - 4.1e-27 94.5 0.1 7e-27 93.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI40295.1 - 2.5e-20 72.5 0.0 3.7e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KPI40295.1 - 5e-18 65.3 0.1 7.6e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI40295.1 - 3.8e-17 62.4 0.0 8.8e-17 61.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI40295.1 - 1.4e-16 61.0 0.1 2.7e-16 60.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI40295.1 - 5.5e-16 58.7 0.1 8.5e-16 58.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KPI40295.1 - 1e-10 41.2 0.0 1.6e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 KPI40295.1 - 4.3e-10 39.2 0.0 6e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KPI40295.1 - 3.1e-09 36.6 0.1 4e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 KPI40295.1 - 4.4e-09 36.3 0.0 8.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KPI40295.1 - 8.6e-09 34.7 0.0 3.5e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_29 PF03141.11 KPI40295.1 - 8e-08 31.0 0.0 9.8e-08 30.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.6 KPI40295.1 - 6.7e-07 28.3 0.2 6.1e-06 25.1 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 KPI40295.1 - 1.6e-05 24.6 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KPI40295.1 - 2.4e-05 23.5 0.0 3.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 KPI40295.1 - 2.5e-05 23.5 0.0 3.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 KPI40295.1 - 3.1e-05 23.6 0.0 7.2e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 DREV PF05219.7 KPI40295.1 - 4.6e-05 22.4 0.0 6.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.6 KPI40295.1 - 0.00025 20.5 0.0 0.00036 19.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_PK PF05891.7 KPI40295.1 - 0.0016 17.7 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase RrnaAD PF00398.15 KPI40295.1 - 0.0039 16.2 0.0 0.0056 15.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.10 KPI40295.1 - 0.0044 16.6 0.2 0.038 13.6 0.1 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_3 PF01596.12 KPI40295.1 - 0.043 12.8 0.0 0.083 11.9 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase CheR PF01739.13 KPI40295.1 - 0.084 12.1 0.1 2 7.6 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain TFIIB PF00382.14 KPI40296.1 - 7.8e-27 92.9 0.0 2.7e-12 46.3 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KPI40296.1 - 1.1e-12 47.0 0.5 1.9e-12 46.2 0.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 KPI40296.1 - 0.00056 19.4 0.0 0.00099 18.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain HTH_Tnp_ISL3 PF13542.1 KPI40296.1 - 0.093 11.9 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 GerE PF00196.14 KPI40296.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family ATP_bind_3 PF01171.15 KPI40296.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family F-box-like_2 PF13013.1 KPI40297.1 - 0.031 14.0 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 F-box-like domain DUF1227 PF06777.6 KPI40298.1 - 1.2e-59 200.2 0.2 2.7e-59 199.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 KPI40298.1 - 2.6e-52 176.7 0.3 4.3e-52 176.0 0.2 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 KPI40298.1 - 1.2e-38 132.6 0.0 3e-38 131.3 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 KPI40298.1 - 0.00066 19.2 0.0 0.14 11.5 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.18 KPI40298.1 - 0.0016 17.3 0.0 0.0072 15.1 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KPI40298.1 - 0.016 15.0 0.1 0.1 12.4 0.1 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 KPI40298.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain Transketolase_N PF00456.16 KPI40299.1 - 1.6e-116 388.7 0.0 2.2e-116 388.3 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KPI40299.1 - 2.2e-25 89.1 0.0 5e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 KPI40299.1 - 1.3e-07 30.8 0.0 0.00015 20.7 0.0 2.5 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 KPI40299.1 - 0.00042 20.2 0.0 0.0013 18.6 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.15 KPI40299.1 - 0.0092 14.7 0.1 0.014 14.0 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KPI40299.1 - 0.019 14.5 2.3 0.061 12.8 0.3 2.4 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PBD PF00786.23 KPI40300.1 - 0.63 10.5 3.2 1.3 9.4 0.1 3.0 2 0 0 2 2 2 0 P21-Rho-binding domain SH3_1 PF00018.23 KPI40302.1 - 1.2e-14 53.3 0.0 2e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KPI40302.1 - 4.2e-14 51.8 0.0 6.7e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KPI40302.1 - 2.8e-09 36.3 0.0 4.3e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain adh_short_C2 PF13561.1 KPI40303.1 - 5e-29 101.7 0.1 5.7e-29 101.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI40303.1 - 3.4e-24 85.6 0.0 4.1e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI40303.1 - 2.7e-11 43.4 0.1 4e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI40303.1 - 3.5e-06 26.6 0.1 4.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI40303.1 - 0.0017 17.0 0.1 0.0023 16.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KPI40303.1 - 0.0072 16.3 0.0 0.016 15.2 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KPI40303.1 - 0.0087 15.1 0.7 0.66 9.0 0.0 2.2 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MA3 PF02847.12 KPI40303.1 - 0.031 13.9 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 MA3 domain Corona_I PF03187.9 KPI40303.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Corona nucleocapsid I protein EXS PF03124.9 KPI40304.1 - 0.11 11.4 0.2 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 EXS family Prominin PF05478.6 KPI40304.1 - 0.14 9.6 0.0 0.21 9.1 0.0 1.2 1 0 0 1 1 1 0 Prominin DUF3951 PF13131.1 KPI40304.1 - 3.1 7.6 8.0 0.3 10.9 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3951) MTH865 PF07747.6 KPI40307.1 - 0.18 11.4 0.5 0.34 10.5 0.4 1.4 1 0 0 1 1 1 0 MTH865-like family Sugar_tr PF00083.19 KPI40309.1 - 3.8e-105 352.0 22.8 5.1e-105 351.6 15.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI40309.1 - 3.8e-28 98.2 30.8 1.2e-26 93.2 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KPI40309.1 - 0.059 13.1 0.2 0.059 13.1 0.2 2.6 3 0 0 3 3 3 0 MFS_1 like family BT1 PF03092.11 KPI40309.1 - 2.7 6.6 13.8 0.25 10.0 1.0 2.6 2 1 0 3 3 3 0 BT1 family DUF726 PF05277.7 KPI40310.1 - 7.1e-96 321.0 0.7 1e-95 320.5 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 KPI40310.1 - 0.0011 18.7 0.4 0.0031 17.2 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI40310.1 - 0.0021 17.9 0.1 0.0072 16.2 0.1 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI40310.1 - 0.0026 17.3 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 KPI40310.1 - 0.067 12.5 0.1 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PE-PPE PF08237.6 KPI40310.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Cutinase PF01083.17 KPI40310.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF3089 PF11288.3 KPI40310.1 - 0.19 10.8 0.0 0.39 9.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Thioesterase PF00975.15 KPI40310.1 - 0.67 10.1 2.7 1.1 9.4 0.0 2.5 4 0 0 4 4 4 0 Thioesterase domain FAD_binding_3 PF01494.14 KPI40311.1 - 6.7e-32 110.9 0.0 1.1e-31 110.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KPI40311.1 - 0.00011 21.3 0.1 0.00022 20.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KPI40311.1 - 0.00041 19.3 0.0 0.00054 18.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI40311.1 - 0.00096 18.1 2.4 0.018 13.9 2.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KPI40311.1 - 0.0014 17.6 0.1 0.0037 16.2 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KPI40311.1 - 0.0036 17.2 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI40311.1 - 0.0038 15.7 1.3 0.0056 15.2 0.9 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 KPI40311.1 - 0.034 14.2 0.1 0.066 13.2 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI40311.1 - 0.12 12.4 0.7 0.26 11.3 0.5 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 KPI40311.1 - 0.22 11.3 0.4 2.4 8.0 0.4 2.1 2 0 0 2 2 2 0 ThiF family NAD_binding_9 PF13454.1 KPI40311.1 - 0.22 11.2 1.0 9.2 6.0 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding OTU PF02338.14 KPI40312.1 - 3.7e-17 63.0 0.2 1.7e-16 60.9 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KPI40312.1 - 1.2e-05 24.8 0.0 0.0027 17.0 0.0 2.7 3 0 0 3 3 3 2 Peptidase C65 Otubain DUF603 PF04645.7 KPI40312.1 - 0.07 13.0 2.6 0.13 12.2 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF603 adh_short PF00106.20 KPI40313.1 - 2.1e-67 226.1 15.1 4.2e-35 121.1 1.2 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KPI40313.1 - 8.2e-32 110.3 9.2 8e-16 58.2 0.3 2.5 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.14 KPI40313.1 - 0.026 13.5 3.5 1.2 8.1 0.4 2.6 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF543 PF04418.7 KPI40313.1 - 0.19 11.6 5.5 2.6 8.0 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF543) 3HCDH_N PF02737.13 KPI40313.1 - 0.5 9.9 9.6 1.7 8.2 0.8 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.17 KPI40314.1 - 5.1e-78 262.6 0.0 6e-78 262.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C5 PF00770.13 KPI40314.1 - 0.097 12.2 0.3 0.18 11.3 0.2 1.4 1 0 0 1 1 1 0 Adenovirus endoprotease F-box-like PF12937.2 KPI40315.1 - 0.016 14.9 0.0 0.048 13.3 0.0 1.9 1 1 0 1 1 1 0 F-box-like F-box PF00646.28 KPI40315.1 - 0.15 11.7 0.0 0.55 9.9 0.0 1.9 2 0 0 2 2 2 0 F-box domain adh_short PF00106.20 KPI40316.1 - 1.3e-08 34.9 1.4 4.2e-08 33.2 1.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI40316.1 - 7.2e-07 29.2 0.0 9.6e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KPI40316.1 - 6.6e-05 22.9 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI40316.1 - 0.0062 16.0 0.0 0.0097 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HHH_5 PF14520.1 KPI40316.1 - 0.022 14.9 0.0 0.48 10.6 0.0 2.5 1 1 1 2 2 2 0 Helix-hairpin-helix domain FAD_binding_4 PF01565.18 KPI40317.1 - 1e-22 80.1 1.7 1.7e-22 79.3 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KPI40317.1 - 0.003 17.4 0.3 0.028 14.3 0.2 2.5 1 1 0 1 1 1 1 Berberine and berberine like PH_2 PF08458.5 KPI40319.1 - 0.031 14.1 0.3 0.075 12.9 0.1 1.7 2 0 0 2 2 2 0 Plant pleckstrin homology-like region Pet127 PF08634.5 KPI40319.1 - 0.062 12.4 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial protein Pet127 CBAH PF02275.13 KPI40320.1 - 2.5e-35 122.4 0.0 4.7e-34 118.2 0.0 2.0 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family ADH_zinc_N PF00107.21 KPI40321.1 - 8.8e-09 34.9 0.0 1.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI40321.1 - 2.7e-07 30.3 0.3 8.8e-07 28.6 0.1 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ATG11 PF10377.4 KPI40323.1 - 8.3e-41 138.8 0.0 8.3e-41 138.8 0.0 4.2 6 0 0 6 6 6 1 Autophagy-related protein 11 APG17 PF04108.7 KPI40323.1 - 7.5e-06 24.9 0.2 7.5e-06 24.9 0.2 6.4 4 2 2 6 6 6 1 Autophagy protein Apg17 Reo_sigmaC PF04582.7 KPI40323.1 - 9.7e-06 24.9 5.6 9.7e-06 24.9 3.9 5.3 5 0 0 5 5 5 3 Reovirus sigma C capsid protein Sipho_Gp157 PF05565.6 KPI40323.1 - 0.026 14.1 0.2 0.026 14.1 0.1 7.6 4 2 3 8 8 8 0 Siphovirus Gp157 CENP-F_leu_zip PF10473.4 KPI40323.1 - 7.8 6.3 85.2 4.6 7.0 15.7 7.5 4 2 2 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DNA_topoisoIV PF00521.15 KPI40324.1 - 2e-126 422.3 0.1 3.2e-126 421.6 0.1 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KPI40324.1 - 4.7e-31 107.3 4.1 1.8e-30 105.4 2.8 2.1 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KPI40324.1 - 1.3e-13 50.8 0.1 7.5e-13 48.3 0.0 2.5 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 KPI40324.1 - 7.3e-11 41.7 0.1 4.3e-10 39.2 0.0 2.2 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tyr_Deacylase PF02580.11 KPI40325.1 - 7.5e-47 158.9 0.0 8.6e-47 158.7 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase TPR_11 PF13414.1 KPI40326.1 - 1.3e-05 24.7 4.7 0.054 13.1 0.9 4.0 3 1 0 3 3 3 2 TPR repeat Foie-gras_1 PF11817.3 KPI40326.1 - 0.0015 18.0 0.2 0.11 11.9 0.0 2.8 3 0 0 3 3 3 1 Foie gras liver health family 1 TPR_19 PF14559.1 KPI40326.1 - 0.0036 17.5 12.0 1.3 9.4 0.0 5.4 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KPI40326.1 - 0.01 16.4 14.6 1.6 9.5 0.1 6.4 5 2 1 7 7 7 0 Tetratricopeptide repeat gpW PF02831.10 KPI40326.1 - 0.013 14.9 0.5 0.6 9.6 0.0 3.1 3 0 0 3 3 3 0 gpW TPR_16 PF13432.1 KPI40326.1 - 0.039 14.6 3.9 4.1 8.1 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 KPI40326.1 - 0.058 13.3 4.8 3.2 7.7 0.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat peroxidase PF00141.18 KPI40327.1 - 1.6e-84 283.0 0.0 4.3e-45 153.9 0.0 2.2 2 0 0 2 2 2 2 Peroxidase ORF6N PF10543.4 KPI40327.1 - 0.017 15.1 0.1 0.071 13.1 0.0 2.0 2 0 0 2 2 2 0 ORF6N domain BTB PF00651.26 KPI40328.1 - 2e-10 40.6 0.0 5.3e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain HEPN PF05168.9 KPI40328.1 - 0.011 15.5 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 HEPN domain DZR PF12773.2 KPI40328.1 - 4.9 7.0 10.6 30 4.5 1.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon MIF4G PF02854.14 KPI40329.1 - 1.9e-18 66.6 0.4 3.5e-18 65.7 0.1 1.6 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 KPI40329.1 - 0.00013 21.6 0.0 0.00028 20.5 0.0 1.7 1 0 0 1 1 1 1 MA3 domain F-box-like PF12937.2 KPI40330.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.4 1 1 0 1 1 1 0 F-box-like F-box-like_2 PF13013.1 KPI40330.1 - 0.12 12.1 0.5 0.4 10.4 0.4 2.0 1 1 0 1 1 1 0 F-box-like domain TRI12 PF06609.8 KPI40331.1 - 2.6e-74 250.4 25.4 3.5e-74 250.1 17.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI40331.1 - 2.2e-31 108.8 47.3 2.7e-30 105.2 31.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI40331.1 - 1.5e-13 50.1 13.1 1.5e-13 50.1 9.1 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter Abhydrolase_6 PF12697.2 KPI40332.1 - 1.5e-31 110.0 0.3 2.7e-31 109.2 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI40332.1 - 8.2e-10 38.6 0.0 5.6e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI40332.1 - 1.5e-08 34.4 0.0 9.5e-07 28.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 KPI40332.1 - 0.0064 15.0 0.0 0.35 9.3 0.0 2.1 2 0 0 2 2 2 2 Ndr family Peptidase_S9 PF00326.16 KPI40332.1 - 0.084 12.0 0.0 1.2 8.3 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family MFS_1 PF07690.11 KPI40333.1 - 9.9e-26 90.2 35.5 1.4e-25 89.7 24.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI40333.1 - 2.3e-07 29.7 29.9 3.1e-07 29.3 5.2 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter PUCC PF03209.10 KPI40333.1 - 0.053 12.2 7.9 0.11 11.1 4.8 2.1 1 1 0 1 1 1 0 PUCC protein G_glu_transpept PF01019.16 KPI40334.1 - 6.9e-139 463.6 0.5 3.4e-138 461.3 0.4 1.8 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase adh_short PF00106.20 KPI40335.1 - 8.8e-17 61.5 0.8 1.5e-16 60.7 0.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI40335.1 - 1.4e-07 31.3 0.5 2.7e-07 30.4 0.3 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KPI40335.1 - 0.0018 18.3 0.3 0.013 15.6 0.1 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase PALP PF00291.20 KPI40335.1 - 0.014 14.6 0.4 0.022 13.9 0.3 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Polysacc_synt_2 PF02719.10 KPI40335.1 - 0.033 13.0 0.4 0.077 11.8 0.1 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KPI40335.1 - 0.065 13.0 1.0 0.19 11.5 0.7 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.20 KPI40336.1 - 5.1e-17 62.3 0.0 8.6e-17 61.5 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI40336.1 - 6.4e-08 32.4 0.0 8.6e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI40336.1 - 2.3e-06 27.5 0.0 3.1e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KPI40336.1 - 8.8e-06 25.3 0.0 1.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI40336.1 - 0.046 13.7 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding MAD PF05557.8 KPI40338.1 - 1.1e-49 169.2 50.1 1.5e-49 168.8 34.7 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Rootletin PF15035.1 KPI40338.1 - 0.0045 17.0 7.2 0.0045 17.0 5.0 5.4 3 2 2 5 5 5 2 Ciliary rootlet component, centrosome cohesion Reo_sigmaC PF04582.7 KPI40338.1 - 0.051 12.7 16.9 0.033 13.3 0.5 3.8 3 2 1 4 4 4 0 Reovirus sigma C capsid protein ADIP PF11559.3 KPI40338.1 - 0.11 12.4 0.2 0.11 12.4 0.1 7.3 2 2 6 8 8 8 0 Afadin- and alpha -actinin-Binding Auxin_repressed PF05564.7 KPI40339.1 - 4.1 8.0 21.0 0.12 12.9 3.8 3.8 2 2 2 4 4 4 0 Dormancy/auxin associated protein Pyr_redox_2 PF07992.9 KPI40341.1 - 9.6e-19 68.0 0.4 1.5e-18 67.4 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI40341.1 - 5.3e-08 31.7 0.3 0.00075 18.0 0.0 2.7 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.1 KPI40341.1 - 4.3e-07 30.2 0.6 0.011 15.7 0.0 2.8 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI40341.1 - 6.6e-07 28.5 5.3 8.2e-05 21.6 0.2 2.5 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 KPI40341.1 - 1.6e-06 27.2 5.6 0.0077 15.1 0.1 2.5 2 1 1 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KPI40341.1 - 7e-06 25.1 0.8 2e-05 23.6 0.0 2.1 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.1 KPI40341.1 - 1.4e-05 24.9 0.8 0.011 15.5 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KPI40341.1 - 2.6e-05 23.3 0.6 0.028 13.3 0.1 2.3 1 1 1 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 KPI40341.1 - 0.005 16.8 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KPI40341.1 - 0.0078 15.3 0.1 2.5 7.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 KPI40341.1 - 0.008 15.2 0.1 0.02 13.9 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KPI40341.1 - 0.02 14.0 0.0 0.055 12.5 0.0 1.7 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KPI40341.1 - 0.41 11.0 1.9 4.3 7.8 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase WAP PF00095.16 KPI40342.1 - 0.0073 16.2 9.0 0.011 15.7 6.3 1.3 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' UQ_con PF00179.21 KPI40343.1 - 3.8e-37 126.8 0.0 5.4e-37 126.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KPI40343.1 - 0.05 13.4 0.1 0.078 12.8 0.0 1.4 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 KPI40343.1 - 0.069 12.8 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.8 KPI40343.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain COQ7 PF03232.8 KPI40345.1 - 1.6e-59 200.2 0.0 2.2e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 UPF0184 PF03670.8 KPI40345.1 - 0.047 13.8 1.3 0.4 10.8 0.9 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) Med3 PF11593.3 KPI40345.1 - 0.43 9.7 14.3 0.55 9.4 9.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NmrA PF05368.8 KPI40346.1 - 4.5e-19 68.6 0.0 6.3e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 KPI40346.1 - 0.0086 15.0 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase MBF1 PF08523.5 KPI40347.1 - 3.6e-22 78.1 3.2 8.3e-22 76.9 2.2 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KPI40347.1 - 3.1e-10 39.7 0.0 4.9e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 KPI40347.1 - 0.00043 20.2 0.0 0.00063 19.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 KPI40347.1 - 0.00045 20.3 0.0 0.00074 19.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain PAM2 PF07145.10 KPI40348.1 - 0.04 13.4 1.1 0.084 12.4 0.7 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region FixQ PF05545.6 KPI40349.1 - 0.12 11.9 0.2 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ EphA2_TM PF14575.1 KPI40349.1 - 0.15 12.4 0.3 0.58 10.5 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 KPI40349.1 - 0.19 11.3 4.1 0.071 12.8 0.8 1.8 2 0 0 2 2 2 0 TMEM154 protein family DUF4366 PF14283.1 KPI40349.1 - 0.21 10.9 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Mucin PF01456.12 KPI40349.1 - 1 9.1 20.0 2.1 8.1 13.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4387 PF14330.1 KPI40351.1 - 3.1e-23 81.9 0.0 5.7e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 KPI40351.1 - 0.00046 18.7 0.0 0.0029 16.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) TP_methylase PF00590.15 KPI40353.1 - 4.8e-19 68.9 0.1 2.3e-18 66.6 0.1 1.9 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases ATP_sub_h PF10775.4 KPI40355.1 - 5.1e-23 80.5 1.4 8.9e-23 79.8 0.9 1.4 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 KPI40355.1 - 0.027 14.3 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 DUF3070 PF11270.3 KPI40355.1 - 0.29 10.9 10.3 0.72 9.6 1.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3070) FAD_binding_4 PF01565.18 KPI40357.1 - 2.3e-22 78.9 0.4 4.7e-22 77.9 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KPI40357.1 - 0.035 14.0 0.0 0.098 12.5 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like FAD_binding_4 PF01565.18 KPI40358.1 - 1e-31 109.2 3.0 1.8e-31 108.4 2.1 1.4 1 0 0 1 1 1 1 FAD binding domain MscS_porin PF12795.2 KPI40360.1 - 0.0008 18.7 18.7 0.0008 18.7 13.0 2.2 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain Laminin_II PF06009.7 KPI40360.1 - 0.012 15.3 5.2 0.012 15.3 3.6 2.4 1 1 0 2 2 2 0 Laminin Domain II P4Ha_N PF08336.6 KPI40360.1 - 0.016 15.0 5.6 0.016 15.0 3.9 3.3 1 1 2 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF3584 PF12128.3 KPI40360.1 - 0.028 11.7 30.1 0.035 11.4 20.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 KPI40360.1 - 0.039 13.5 38.6 0.1 12.1 2.8 2.5 1 1 1 2 2 2 0 IncA protein CASP_C PF08172.7 KPI40360.1 - 0.053 12.5 0.1 0.053 12.5 0.0 3.7 1 1 3 4 4 4 0 CASP C terminal IR1-M PF12185.3 KPI40360.1 - 0.71 9.6 9.8 0.092 12.4 2.0 2.8 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain DUF1759 PF03564.10 KPI40360.1 - 0.88 9.3 10.2 0.16 11.8 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) YlqD PF11068.3 KPI40360.1 - 1.3 9.0 38.2 0.36 10.8 6.2 3.1 1 1 2 3 3 3 0 YlqD protein NPV_P10 PF05531.7 KPI40360.1 - 2.7 8.3 12.1 18 5.6 5.2 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4164 PF13747.1 KPI40360.1 - 3.5 7.8 19.4 3.6 7.8 6.1 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Latarcin PF10279.4 KPI40360.1 - 4.2 7.6 14.3 80 3.5 0.0 3.5 1 1 1 2 2 1 0 Latarcin precursor Prominin PF05478.6 KPI40360.1 - 6.4 4.1 9.3 8.8 3.7 6.5 1.3 1 0 0 1 1 1 0 Prominin Histidinol_dh PF00815.15 KPI40360.1 - 6.5 5.2 6.8 9.1 4.7 4.7 1.3 1 0 0 1 1 1 0 Histidinol dehydrogenase Ank_2 PF12796.2 KPI40361.1 - 7.2e-37 125.6 10.8 1.2e-09 38.3 0.7 5.7 3 1 4 7 7 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 KPI40361.1 - 2.8e-21 74.1 14.1 7.4e-05 22.3 0.0 9.1 9 0 0 9 9 9 4 Ankyrin repeat Ank_3 PF13606.1 KPI40361.1 - 4.5e-19 66.6 5.8 1.4e-05 24.8 0.0 9.1 10 0 0 10 10 9 3 Ankyrin repeat Ank_4 PF13637.1 KPI40361.1 - 5e-18 65.1 6.1 2.4e-08 34.2 0.0 6.8 6 1 1 7 7 6 4 Ankyrin repeats (many copies) HET PF06985.6 KPI40361.1 - 4.1e-16 59.3 7.1 7.5e-14 52.0 4.9 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 KPI40361.1 - 4.1e-10 39.5 0.0 1.3e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.1 KPI40361.1 - 8.3e-10 38.5 14.6 0.015 15.5 0.2 8.1 6 4 4 10 10 8 3 Ankyrin repeats (many copies) AAA_16 PF13191.1 KPI40361.1 - 4.9e-05 23.3 0.7 0.011 15.7 0.0 3.4 2 1 1 3 3 3 1 AAA ATPase domain KAP_NTPase PF07693.9 KPI40361.1 - 0.011 14.7 2.4 0.051 12.5 1.6 1.8 1 1 0 1 1 1 0 KAP family P-loop domain RNA_helicase PF00910.17 KPI40361.1 - 0.016 15.4 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 KPI40361.1 - 0.027 14.6 0.0 0.088 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 KPI40361.1 - 0.034 12.9 0.1 0.1 11.3 0.1 1.7 1 1 0 1 1 1 0 MCM2/3/5 family AAA PF00004.24 KPI40361.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KPI40361.1 - 0.17 11.6 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 KPI40361.1 - 0.19 10.6 0.0 0.34 9.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HET PF06985.6 KPI40365.1 - 1.3e-31 109.5 0.1 2.2e-31 108.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APG6 PF04111.7 KPI40366.1 - 0.029 13.4 0.7 0.054 12.5 0.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Rab5-bind PF09311.6 KPI40366.1 - 0.25 11.2 6.3 0.7 9.7 4.1 1.8 2 0 0 2 2 2 0 Rabaptin-like protein DUF4407 PF14362.1 KPI40366.1 - 0.36 9.7 2.8 0.58 9.0 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.9 KPI40366.1 - 0.71 9.4 3.6 1.2 8.7 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) OmpH PF03938.9 KPI40366.1 - 1.7 8.5 4.6 0.29 11.0 0.6 1.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) MAP65_ASE1 PF03999.7 KPI40366.1 - 1.9 7.0 10.4 0.07 11.7 3.0 1.6 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Mnd1 PF03962.10 KPI40366.1 - 4.7 6.8 7.2 0.39 10.3 1.3 1.7 2 0 0 2 2 2 0 Mnd1 family His_Phos_1 PF00300.17 KPI40367.1 - 5.1e-13 49.4 0.2 9.2e-08 32.3 0.1 2.3 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Inh PF02974.9 KPI40368.1 - 0.072 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Protease inhibitor Inh F-box-like PF12937.2 KPI40369.1 - 0.0024 17.5 0.0 0.0054 16.4 0.0 1.6 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KPI40370.1 - 0.065 12.9 2.9 0.23 11.1 2.0 2.0 1 0 0 1 1 1 0 F-box domain COesterase PF00135.23 KPI40371.1 - 8.1e-24 84.2 0.0 9.5e-24 83.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family p450 PF00067.17 KPI40372.1 - 4.2e-67 226.6 0.0 5.3e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 COesterase PF00135.23 KPI40373.1 - 1.3e-72 245.2 0.0 1.6e-72 244.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI40373.1 - 6.5e-06 25.8 0.2 2.5e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KPI40373.1 - 0.065 11.8 0.0 0.26 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KPI40373.1 - 0.087 12.0 0.1 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family BTB PF00651.26 KPI40374.1 - 7.1e-10 38.8 0.0 1.8e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain HEPN PF05168.9 KPI40374.1 - 0.068 13.0 0.0 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 HEPN domain HET PF06985.6 KPI40375.1 - 1.1e-11 45.0 8.7 2.9e-09 37.2 6.0 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1446 PF07287.6 KPI40376.1 - 1.3e-108 362.7 0.1 1.6e-108 362.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) DUF3445 PF11927.3 KPI40378.1 - 5.8e-75 251.8 0.0 8.3e-75 251.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Lentivirus_VIF PF05851.6 KPI40378.1 - 0.093 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) Amino_oxidase PF01593.19 KPI40379.1 - 4.2e-50 171.1 1.3 6.9e-49 167.1 0.9 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KPI40379.1 - 1.8e-14 53.5 0.4 5.2e-14 52.0 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KPI40379.1 - 4.4e-06 26.5 0.3 0.0094 15.7 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KPI40379.1 - 1.1e-05 25.5 1.3 0.00039 20.5 1.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI40379.1 - 1.1e-05 25.6 3.8 0.00012 22.3 0.8 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI40379.1 - 0.00019 21.3 1.5 0.041 13.7 0.5 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI40379.1 - 0.0002 20.3 4.1 0.0018 17.2 2.9 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KPI40379.1 - 0.00034 19.7 0.2 0.00064 18.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.16 KPI40379.1 - 0.00054 19.5 0.2 0.0011 18.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 KPI40379.1 - 0.00084 18.4 0.6 0.0016 17.5 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KPI40379.1 - 0.0068 14.9 1.6 0.013 14.0 1.1 1.4 1 0 0 1 1 1 1 HI0933-like protein FMO-like PF00743.14 KPI40379.1 - 0.024 12.8 0.1 0.035 12.3 0.1 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like GIDA PF01134.17 KPI40379.1 - 0.031 13.1 2.2 0.25 10.1 1.6 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KPI40379.1 - 0.041 13.5 0.8 0.082 12.5 0.6 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KPI40379.1 - 0.071 11.9 3.7 1 8.1 2.1 2.1 2 0 0 2 2 2 0 FAD binding domain FmdA_AmdA PF03069.10 KPI40381.1 - 4.6e-152 505.9 0.0 5.3e-152 505.7 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family DUF498 PF04430.9 KPI40381.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) APH PF01636.18 KPI40382.1 - 9.8e-16 58.2 0.4 1.7e-15 57.4 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KPI40382.1 - 7.3e-05 22.4 0.0 0.00022 20.8 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.20 KPI40382.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain SRP14 PF02290.10 KPI40383.1 - 3.3e-23 81.4 0.3 4.5e-23 80.9 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Fcf2 PF08698.6 KPI40383.1 - 0.048 13.6 0.4 0.067 13.2 0.3 1.2 1 0 0 1 1 1 0 Fcf2 pre-rRNA processing F-box-like PF12937.2 KPI40384.1 - 0.027 14.1 0.0 0.071 12.8 0.0 1.8 1 1 0 1 1 1 0 F-box-like Thiolase_N PF00108.18 KPI40386.1 - 8e-93 310.2 1.0 1.5e-92 309.3 0.7 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KPI40386.1 - 2.3e-39 133.5 0.9 2.3e-39 133.5 0.6 2.1 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KPI40386.1 - 0.00015 21.3 4.6 0.00056 19.4 0.8 2.6 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KPI40386.1 - 0.17 11.5 5.7 4 7.1 0.1 3.2 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Epimerase PF01370.16 KPI40387.1 - 4.3e-13 49.2 0.0 7.3e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI40387.1 - 1.9e-09 37.8 1.4 0.00051 20.0 0.3 2.7 2 1 0 2 2 2 2 NADH(P)-binding adh_short PF00106.20 KPI40387.1 - 3.9e-07 30.1 0.0 1.3e-06 28.4 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 KPI40387.1 - 0.0011 18.2 0.0 0.0024 17.1 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KPI40387.1 - 0.0021 17.0 0.0 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Abhydrolase_3 PF07859.8 KPI40388.1 - 9.8e-34 116.7 0.1 1.6e-33 116.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCM PF04072.9 KPI40390.1 - 7.9e-38 129.8 0.2 1.1e-37 129.4 0.1 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF2605 PF10792.4 KPI40390.1 - 0.089 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) LCM PF04072.9 KPI40391.1 - 1.1e-13 51.1 0.5 7e-10 38.7 0.1 2.8 2 1 0 2 2 2 2 Leucine carboxyl methyltransferase Fungal_trans PF04082.13 KPI40392.1 - 0.01 14.7 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Fungal_trans PF04082.13 KPI40393.1 - 9.8e-15 54.1 0.4 9.8e-15 54.1 0.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI40393.1 - 1.6e-07 31.1 12.4 3.4e-07 30.0 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.23 KPI40394.1 - 2.2e-79 267.6 0.0 3.3e-79 267.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI40394.1 - 0.015 14.9 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold F-box-like_2 PF13013.1 KPI40395.1 - 0.00023 20.8 0.0 0.00048 19.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain MRC1 PF09444.5 KPI40396.1 - 3.6e-31 108.4 22.0 3.6e-31 108.4 15.3 7.9 7 2 0 7 7 7 1 MRC1-like domain Pyr_redox_3 PF13738.1 KPI40397.1 - 1e-26 94.2 0.0 8.2e-25 88.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI40397.1 - 4e-17 61.6 0.2 4.8e-16 58.0 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI40397.1 - 2.6e-12 46.5 0.0 3.6e-10 39.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI40397.1 - 3.9e-12 45.7 0.2 4e-09 35.8 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KPI40397.1 - 8.2e-11 41.3 0.7 4.3e-06 25.8 0.0 3.8 2 1 1 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI40397.1 - 2e-06 27.8 0.0 0.0058 16.5 0.0 3.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI40397.1 - 4.3e-06 25.8 0.1 0.0045 15.9 0.0 3.4 3 1 1 4 4 4 1 Lycopene cyclase protein Thi4 PF01946.12 KPI40397.1 - 7.1e-06 25.2 0.0 0.00015 20.9 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KPI40397.1 - 9.4e-05 22.7 0.0 0.33 11.3 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 KPI40397.1 - 0.00013 20.2 0.1 0.34 9.0 0.0 2.4 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.1 KPI40397.1 - 0.00025 20.8 1.3 0.31 10.7 0.0 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KPI40397.1 - 0.0036 17.4 0.0 0.44 10.6 0.0 3.1 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.19 KPI40397.1 - 0.0081 15.2 0.0 0.036 13.1 0.0 1.9 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KPI40397.1 - 0.025 13.4 0.1 0.18 10.6 0.0 2.3 3 0 0 3 3 3 0 FAD binding domain Trp_halogenase PF04820.9 KPI40397.1 - 0.039 12.5 0.2 2.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.1 KPI40397.1 - 0.097 12.9 0.0 1.5 9.1 0.0 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding HI0933_like PF03486.9 KPI40397.1 - 0.11 11.0 0.3 2.2 6.6 0.0 2.9 4 0 0 4 4 4 0 HI0933-like protein GIDA PF01134.17 KPI40397.1 - 0.19 10.5 1.8 8.1 5.1 0.1 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A Abhydrolase_6 PF12697.2 KPI40398.1 - 3.7e-18 66.2 0.0 5.1e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI40398.1 - 8.1e-07 28.8 0.0 6.9e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI40398.1 - 0.0025 17.5 0.0 0.0046 16.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.7 KPI40398.1 - 0.12 11.1 0.0 0.34 9.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Adaptin_N PF01602.15 KPI40399.1 - 1.1e-146 489.2 2.0 1.5e-146 488.8 1.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KPI40399.1 - 9.2e-26 90.7 0.2 1.2e-24 87.1 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KPI40399.1 - 7.9e-19 67.7 0.0 2.3e-08 34.1 0.0 5.2 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 KPI40399.1 - 1.2e-12 46.7 2.2 0.0039 17.1 0.0 6.0 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 KPI40399.1 - 2.7e-05 24.5 1.7 4.7 7.8 0.0 6.1 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 KPI40399.1 - 0.0039 16.5 0.4 0.82 8.9 0.0 3.5 2 1 1 3 3 3 1 CLASP N terminal Arm PF00514.18 KPI40399.1 - 0.0071 16.1 0.7 4.7 7.1 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat bZIP_1 PF00170.16 KPI40401.1 - 0.00074 19.4 2.4 0.0014 18.4 1.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor V_ATPase_I PF01496.14 KPI40401.1 - 0.16 9.8 0.2 0.18 9.6 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SAGA-Tad1 PF12767.2 KPI40401.1 - 0.26 10.9 5.4 0.37 10.3 3.7 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Deltaretro_Tax PF05599.6 KPI40401.1 - 0.34 11.2 4.5 0.41 10.9 2.1 1.8 1 1 0 2 2 2 0 Deltaretrovirus Tax protein bZIP_2 PF07716.10 KPI40401.1 - 2.4 8.0 12.3 10 6.0 8.5 2.0 1 1 0 1 1 1 0 Basic region leucine zipper MFS_1 PF07690.11 KPI40402.1 - 2.7e-26 92.1 21.7 1.9e-14 53.1 2.5 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF809 PF05663.6 KPI40402.1 - 0.11 12.4 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF809) NfeD PF01957.13 KPI40402.1 - 0.4 10.8 9.1 5.3 7.1 0.1 3.6 2 1 0 3 3 3 0 NfeD-like C-terminal, partner-binding EXS PF03124.9 KPI40402.1 - 1.3 7.9 9.9 0.034 13.1 1.2 2.4 3 0 0 3 3 3 0 EXS family Sugar_tr PF00083.19 KPI40403.1 - 1.2e-91 307.5 20.8 1.5e-91 307.2 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI40403.1 - 9.7e-28 96.8 19.6 9.7e-28 96.8 13.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily BTB PF00651.26 KPI40404.1 - 0.0031 17.4 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Glyco_hydro_76 PF03663.9 KPI40405.1 - 3.5e-123 411.6 13.2 4.4e-123 411.3 9.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KPI40405.1 - 0.02 13.9 0.8 0.02 13.9 0.5 2.7 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 EHN PF06441.7 KPI40406.1 - 1.4e-23 82.9 1.3 4.8e-23 81.2 0.9 1.9 1 1 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KPI40406.1 - 6.5e-16 58.8 0.6 1e-15 58.2 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI40406.1 - 9.1e-08 31.9 0.0 9.6e-07 28.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI40406.1 - 0.049 13.3 0.0 0.075 12.7 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Isochorismatase PF00857.15 KPI40407.1 - 1.4e-44 152.0 0.0 1.7e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family adh_short PF00106.20 KPI40408.1 - 6.4e-19 68.4 0.0 2.1e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KPI40408.1 - 2.8e-06 27.2 0.0 0.004 16.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI40408.1 - 1.4e-05 24.8 0.0 0.0062 16.2 0.0 2.2 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 KPI40408.1 - 0.0024 17.8 0.0 0.0039 17.2 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KPI40408.1 - 0.038 13.7 0.3 0.09 12.5 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KPI40408.1 - 0.04 13.3 0.0 0.7 9.2 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family TLD PF07534.11 KPI40409.1 - 6.3e-09 35.9 0.0 9.8e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 TLD CRAL_TRIO PF00650.15 KPI40410.1 - 2.7e-45 153.7 0.0 6.2e-45 152.5 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KPI40410.1 - 1.5e-15 57.0 0.2 5.6e-15 55.2 0.0 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KPI40410.1 - 3.8e-11 43.1 0.0 7.2e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Methyltransf_12 PF08242.7 KPI40410.1 - 7.2e-11 42.4 0.1 2.7e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI40410.1 - 1.2e-09 37.9 0.0 2.5e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI40410.1 - 2.2e-09 37.6 0.0 5.2e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI40410.1 - 5.9e-08 32.5 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI40410.1 - 9.2e-07 29.4 0.3 3.1e-06 27.7 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI40410.1 - 1.6e-05 25.2 0.0 4.3e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI40410.1 - 0.00042 19.5 0.0 0.00086 18.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KPI40410.1 - 0.0052 16.8 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.1 KPI40411.1 - 9e-34 117.2 0.2 1.1e-33 117.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI40411.1 - 2.5e-24 86.0 2.7 3.1e-24 85.7 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI40411.1 - 1.5e-09 37.7 1.2 2.1e-09 37.3 0.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI40411.1 - 0.00056 19.4 0.1 0.00078 18.9 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 KPI40411.1 - 0.0066 16.2 0.4 0.03 14.1 0.3 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KPI40411.1 - 0.0094 15.6 0.3 0.014 15.0 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KPI40411.1 - 0.066 12.2 0.2 0.14 11.2 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TcpA PF05946.7 KPI40411.1 - 0.09 12.6 0.1 1.9 8.3 0.0 2.6 2 1 0 2 2 2 0 Toxin-coregulated pilus subunit TcpA Fungal_trans_2 PF11951.3 KPI40413.1 - 4.5e-07 28.7 0.0 5.9e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain SSXT PF05030.7 KPI40414.1 - 0.00024 20.6 1.2 0.42 10.2 0.0 2.7 3 0 0 3 3 3 2 SSXT protein (N-terminal region) Ribonuclease_3 PF00636.21 KPI40415.1 - 1e-13 51.7 0.0 2.4e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KPI40415.1 - 2.2e-13 50.3 0.0 4.7e-13 49.2 0.0 1.5 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.20 KPI40415.1 - 0.0054 17.2 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Cupin_2 PF07883.6 KPI40416.1 - 3.3e-06 26.4 0.0 5.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain DUF2917 PF11142.3 KPI40416.1 - 0.021 14.0 0.0 0.051 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) Glyco_trans_1_4 PF13692.1 KPI40417.1 - 3.4e-25 88.7 0.0 9.8e-25 87.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KPI40417.1 - 7e-05 22.3 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KPI40417.1 - 0.00039 20.6 0.5 0.00092 19.3 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Peptidase_S28 PF05577.7 KPI40418.1 - 9.2e-37 126.6 0.2 5.2e-36 124.1 0.2 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 SUN PF03856.8 KPI40419.1 - 6.8e-76 254.8 13.3 9.4e-76 254.3 9.2 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Aldo_ket_red PF00248.16 KPI40420.1 - 5.1e-49 166.6 0.0 6.1e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SnoaL_4 PF13577.1 KPI40422.1 - 4.4e-05 23.4 0.1 5.6e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 KPI40422.1 - 0.00049 20.4 0.1 0.00061 20.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KPI40422.1 - 0.029 14.5 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) His_Phos_1 PF00300.17 KPI40424.1 - 2.3e-15 57.0 0.0 3.6e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Fungal_trans PF04082.13 KPI40425.1 - 3.7e-22 78.4 0.3 3.7e-22 78.4 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI40425.1 - 1.6e-07 31.0 9.8 3.4e-07 30.0 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 KPI40427.1 - 2.2e-14 53.4 0.0 3.6e-13 49.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI40427.1 - 3.7e-05 23.3 0.0 0.005 16.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KPI40427.1 - 0.00055 20.3 0.0 0.0013 19.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI40427.1 - 0.0013 19.1 0.0 0.0059 17.0 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI40427.1 - 0.0027 18.2 0.6 0.18 12.4 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI40427.1 - 0.072 13.1 0.1 2.3 8.2 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain UPF0546 PF10639.4 KPI40428.1 - 1e-35 121.9 0.9 1.4e-35 121.5 0.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 DUF2985 PF11204.3 KPI40428.1 - 0.012 15.3 2.7 0.93 9.2 0.1 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2985) EamA PF00892.15 KPI40428.1 - 0.027 14.4 4.9 0.088 12.8 2.0 2.2 2 0 0 2 2 2 0 EamA-like transporter family zf-primase PF09329.6 KPI40429.1 - 1.1e-14 53.7 0.8 1.9e-14 52.9 0.5 1.4 1 0 0 1 1 1 1 Primase zinc finger FAD_binding_3 PF01494.14 KPI40431.1 - 1.7e-48 165.4 0.0 2.5e-48 164.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI40431.1 - 5.8e-05 22.1 0.1 0.00016 20.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI40431.1 - 0.00013 21.8 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI40431.1 - 0.00045 19.1 0.0 0.00071 18.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KPI40431.1 - 0.0013 18.6 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI40431.1 - 0.0017 18.4 0.1 0.003 17.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI40431.1 - 0.0034 15.9 0.0 0.0048 15.4 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.5 KPI40431.1 - 0.0046 15.8 0.0 0.055 12.2 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.22 KPI40431.1 - 0.0083 16.5 0.0 0.087 13.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KPI40431.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 KPI40431.1 - 0.013 14.6 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 KPI40431.1 - 0.027 13.3 0.1 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 KPI40431.1 - 0.046 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding p450 PF00067.17 KPI40433.1 - 3.6e-67 226.8 0.0 4.8e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 C2 PF00168.25 KPI40436.1 - 2.4e-13 49.7 0.0 4.2e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain MFS_1 PF07690.11 KPI40437.1 - 8.8e-17 60.8 32.6 2.3e-09 36.4 13.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI40437.1 - 3.3e-15 55.6 24.4 2.5e-14 52.7 16.9 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter FAD_binding_3 PF01494.14 KPI40439.1 - 3.2e-08 33.0 0.0 3.2e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Plus-3 PF03126.13 KPI40440.1 - 6.2e-24 84.1 0.0 1.5e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 Plus-3 domain Fungal_trans PF04082.13 KPI40441.1 - 3.2e-18 65.5 3.1 5.4e-18 64.8 1.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI40441.1 - 2e-09 37.1 12.3 3.1e-09 36.5 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FliJ PF02050.11 KPI40441.1 - 0.46 10.5 2.8 0.6 10.1 0.2 2.4 3 0 0 3 3 3 0 Flagellar FliJ protein bZIP_1 PF00170.16 KPI40441.1 - 0.55 10.2 6.6 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF4559 PF15112.1 KPI40441.1 - 3.2 6.8 6.3 4.2 6.4 3.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) DUF3278 PF11683.3 KPI40442.1 - 0.074 13.0 1.4 0.12 12.3 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) YtpI PF14007.1 KPI40442.1 - 0.47 10.4 6.1 0.6 10.0 3.7 1.6 1 1 0 1 1 1 0 YtpI-like protein DUF4231 PF14015.1 KPI40442.1 - 1.8 8.5 4.0 4.7 7.2 2.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Evr1_Alr PF04777.8 KPI40443.1 - 1.2e-26 92.4 1.4 3.4e-26 90.9 0.4 1.9 2 0 0 2 2 2 1 Erv1 / Alr family DUF755 PF05501.6 KPI40443.1 - 0.46 10.5 8.3 1.1 9.2 5.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) NmrA PF05368.8 KPI40444.1 - 2e-14 53.4 0.0 2.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI40444.1 - 2.7e-11 43.7 0.1 7.7e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 KPI40444.1 - 1.2e-07 31.0 0.0 1.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KPI40444.1 - 5.2e-06 26.7 0.0 8.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 KPI40444.1 - 4.1e-05 23.1 0.0 7.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KPI40444.1 - 5.5e-05 22.2 0.1 0.00047 19.1 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 KPI40444.1 - 0.00023 19.9 0.0 0.00035 19.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KPI40444.1 - 0.0027 17.6 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus CoA_binding_2 PF13380.1 KPI40444.1 - 0.022 14.8 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain DUF427 PF04248.7 KPI40445.1 - 1.4e-15 56.7 0.5 2.4e-15 55.9 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF427) DUF3328 PF11807.3 KPI40447.1 - 0.017 14.7 0.0 0.017 14.7 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) COX4 PF02936.9 KPI40447.1 - 0.048 13.3 1.6 0.054 13.2 0.0 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Mitofilin PF09731.4 KPI40447.1 - 0.064 11.9 7.7 0.071 11.7 5.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Synaptobrevin PF00957.16 KPI40447.1 - 0.12 11.9 0.4 0.31 10.6 0.3 1.6 1 0 0 1 1 1 0 Synaptobrevin TP53IP5 PF15331.1 KPI40447.1 - 0.23 11.3 4.6 0.35 10.7 3.2 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DNA_binding_1 PF01035.15 KPI40448.1 - 2.7e-20 71.8 0.0 5.7e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Acyl-CoA_dh_1 PF00441.19 KPI40449.1 - 3.3e-18 66.2 2.7 6.7e-18 65.2 1.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KPI40449.1 - 8e-08 31.6 0.0 2e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KPI40449.1 - 1.6e-07 31.8 0.0 9.5e-07 29.3 0.0 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KPI40449.1 - 0.0023 18.1 0.8 0.0023 18.1 0.5 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans_2 PF11951.3 KPI40450.1 - 1.3e-46 158.9 3.6 1.9e-46 158.4 2.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Porphobil_deam PF01379.15 KPI40450.1 - 0.064 12.1 0.0 0.17 10.7 0.0 1.7 2 0 0 2 2 2 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain zf-CCHC PF00098.18 KPI40451.1 - 1.3e-40 135.3 82.8 1.4e-06 27.9 3.0 10.3 10 0 0 10 10 10 9 Zinc knuckle zf-CCHC_4 PF14392.1 KPI40451.1 - 1.4e-06 27.8 63.2 0.29 10.8 0.3 10.3 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_2 PF13696.1 KPI40451.1 - 5.5e-05 22.5 41.3 0.0037 16.7 0.0 8.3 7 2 2 9 9 9 3 Zinc knuckle zf-CCHC_6 PF15288.1 KPI40451.1 - 0.012 15.3 1.0 0.012 15.3 0.7 8.9 7 3 3 10 10 10 0 Zinc knuckle zf-CCHC_3 PF13917.1 KPI40451.1 - 0.22 11.3 63.4 0.3 10.8 0.6 9.2 4 2 4 8 8 8 0 Zinc knuckle SBF PF01758.11 KPI40452.1 - 8.4e-50 168.7 13.6 8.4e-50 168.7 9.4 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF3671 PF12420.3 KPI40452.1 - 0.27 11.2 1.2 5.2 7.1 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function DUF2388 PF09498.5 KPI40454.1 - 0.0016 18.0 0.2 0.023 14.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2388) MORN_2 PF07661.8 KPI40454.1 - 0.14 12.2 0.1 0.52 10.5 0.1 1.9 1 0 0 1 1 1 0 MORN repeat variant PDZ_1 PF12812.2 KPI40455.1 - 6e-53 176.6 0.0 3.2e-35 119.8 0.0 3.0 3 0 0 3 3 3 2 PDZ-like domain PDZ_2 PF13180.1 KPI40455.1 - 3.7e-14 52.3 0.2 8.5e-05 22.3 0.0 4.6 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 KPI40455.1 - 5.6e-13 48.9 0.9 2e-10 40.6 0.0 3.2 2 1 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 KPI40455.1 - 8.1e-13 48.3 0.1 1.3e-05 25.3 0.0 3.8 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 KPI40455.1 - 1.3e-06 28.1 0.3 0.00061 19.4 0.0 3.2 2 1 0 2 2 2 1 Trypsin Tricorn_PDZ PF14685.1 KPI40455.1 - 0.00085 19.0 0.1 0.14 11.9 0.0 3.4 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.4 KPI40455.1 - 0.007 14.8 0.1 0.014 13.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase S46 Peptidase_S7 PF00949.16 KPI40455.1 - 0.08 12.3 0.2 0.21 10.9 0.1 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 KPI40455.1 - 0.17 11.2 0.4 0.27 10.5 0.2 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) Med4 PF10018.4 KPI40456.1 - 2.3e-20 72.8 12.3 5.1e-20 71.6 8.5 1.6 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 TMF_DNA_bd PF12329.3 KPI40456.1 - 0.05 13.4 5.9 0.62 9.9 0.0 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 KPI40456.1 - 0.085 12.3 3.2 4.9 6.7 0.2 2.8 2 0 0 2 2 2 0 Septum formation initiator TPR_MLP1_2 PF07926.7 KPI40456.1 - 0.28 10.9 8.1 0.87 9.3 5.2 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DNA_primase_S PF01896.14 KPI40457.1 - 4.6e-36 123.7 0.0 7.4e-36 123.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit EPSP_synthase PF00275.15 KPI40458.1 - 7.6e-125 416.6 0.0 1.3e-124 415.8 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 KPI40458.1 - 4.1e-91 304.5 0.0 8.7e-91 303.4 0.0 1.5 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 KPI40458.1 - 6.9e-61 205.7 0.0 1.1e-60 205.0 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KPI40458.1 - 3e-35 121.4 0.0 5.4e-34 117.3 0.0 2.8 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.6 KPI40458.1 - 1.5e-23 82.6 0.0 4.4e-23 81.1 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.1 KPI40458.1 - 1.9e-09 37.2 0.0 4.1e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.15 KPI40458.1 - 5e-06 26.6 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_18 PF13238.1 KPI40458.1 - 0.00012 22.3 0.1 0.00035 20.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KPI40458.1 - 0.00046 20.9 0.5 0.0019 19.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KPI40458.1 - 0.044 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 KPI40460.1 - 1.5e-68 230.7 0.0 1.8e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI40460.1 - 4.2e-31 107.9 0.0 5.9e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KPI40460.1 - 0.028 14.1 2.1 0.049 13.3 0.1 2.4 2 2 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 KPI40460.1 - 0.11 11.5 0.0 0.3 10.1 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BTB PF00651.26 KPI40461.1 - 1.5e-10 40.9 0.0 3.3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain HEPN PF05168.9 KPI40461.1 - 0.03 14.2 0.1 0.072 12.9 0.0 1.6 2 0 0 2 2 2 0 HEPN domain FAA_hydrolase PF01557.13 KPI40462.1 - 1.3e-61 207.8 0.0 1.7e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Adaptin_binding PF10199.4 KPI40463.1 - 3.8e-05 23.9 3.7 4.5e-05 23.7 2.6 1.2 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 SPATIAL PF15256.1 KPI40463.1 - 0.13 12.2 1.4 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 SPATIAL CDC45 PF02724.9 KPI40463.1 - 0.32 8.9 9.8 0.4 8.6 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 KPI40463.1 - 1.2 8.3 5.9 1.9 7.6 4.1 1.4 1 0 0 1 1 1 0 NOA36 protein TPR_11 PF13414.1 KPI40464.1 - 3.6e-10 39.3 3.3 2.4e-07 30.3 0.3 2.7 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KPI40464.1 - 2.1e-09 36.5 0.6 0.0061 16.1 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KPI40464.1 - 0.00056 19.6 2.5 6.2 6.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KPI40464.1 - 0.0025 17.9 0.3 0.0056 16.7 0.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Hex_IIIa PF02455.11 KPI40464.1 - 0.0071 15.0 0.3 0.011 14.5 0.2 1.2 1 0 0 1 1 1 1 Hexon-associated protein (IIIa) DUF3715 PF12509.3 KPI40464.1 - 0.054 13.3 0.2 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3715) TPR_17 PF13431.1 KPI40464.1 - 0.076 13.2 0.5 0.52 10.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KPI40464.1 - 0.17 12.6 0.1 0.17 12.6 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat GnsAB PF08178.6 KPI40464.1 - 1.8 8.2 4.7 0.43 10.2 0.4 2.1 2 0 0 2 2 2 0 GnsA/GnsB family MRP-S33 PF08293.6 KPI40465.1 - 1.8e-28 98.3 0.2 2.4e-28 97.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 F-box-like PF12937.2 KPI40466.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.6 1 1 0 1 1 1 0 F-box-like Ribosomal_L7Ae PF01248.21 KPI40467.1 - 1.6e-25 88.4 0.0 2e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KPI40467.1 - 0.00048 19.9 0.0 0.00056 19.7 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 KPI40467.1 - 0.0097 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain DUF2935 PF11155.3 KPI40468.1 - 0.093 12.8 0.2 1 9.4 0.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) p450 PF00067.17 KPI40469.1 - 2.5e-68 230.6 0.0 3.2e-68 230.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 IFT46_B_C PF12317.3 KPI40469.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Polyketide_cyc2 PF10604.4 KPI40470.1 - 5.4e-08 33.1 0.0 6.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 KPI40470.1 - 0.0024 17.8 0.0 0.0038 17.2 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Homoserine_dh PF00742.14 KPI40472.1 - 3.3e-51 173.5 0.0 4.2e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KPI40472.1 - 1.1e-11 45.1 0.0 4.4e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain SNase PF00565.12 KPI40472.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Staphylococcal nuclease homologue Fungal_trans PF04082.13 KPI40473.1 - 8.1e-08 31.4 0.4 1.2e-07 30.9 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_8 PF13450.1 KPI40475.1 - 5.3e-12 45.5 0.0 1.4e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI40475.1 - 2.1e-07 30.1 0.0 9.5e-06 24.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI40475.1 - 4.2e-07 30.0 0.0 0.0053 16.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI40475.1 - 2.4e-05 24.4 0.0 5.5e-05 23.3 0.0 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KPI40475.1 - 5.7e-05 22.3 0.0 0.0072 15.4 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KPI40475.1 - 0.00019 20.4 0.0 0.00029 19.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KPI40475.1 - 0.00026 19.6 0.1 0.015 13.8 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 KPI40475.1 - 0.00026 20.7 0.0 0.014 15.1 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KPI40475.1 - 0.00078 19.7 0.0 1.2 9.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI40475.1 - 0.005 15.9 0.0 0.0095 15.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 KPI40475.1 - 0.0082 15.1 0.1 0.014 14.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Shikimate_DH PF01488.15 KPI40475.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KPI40475.1 - 0.021 13.9 0.0 0.21 10.6 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 KPI40475.1 - 0.22 10.3 0.1 0.32 9.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 KPI40475.1 - 0.26 10.3 0.5 0.99 8.4 0.0 2.1 2 1 0 2 2 2 0 FAD dependent oxidoreductase DUF1907 PF08925.6 KPI40477.1 - 1.4e-73 247.4 0.0 2.7e-73 246.5 0.0 1.4 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1907) Formyl_trans_N PF00551.14 KPI40478.1 - 8.4e-40 136.2 0.2 1.3e-39 135.5 0.1 1.3 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 KPI40478.1 - 1e-08 34.4 0.0 7.4e-08 31.7 0.0 2.4 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.1 KPI40478.1 - 2.4e-05 23.9 0.0 5.9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 ACT domain Glyco_trans_4_2 PF13477.1 KPI40478.1 - 0.0055 16.5 0.1 0.0099 15.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like TroA PF01297.12 KPI40478.1 - 0.033 13.4 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic solute binding protein family Acetyltransf_1 PF00583.19 KPI40479.1 - 0.0026 17.7 0.2 0.005 16.8 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Sugar_tr PF00083.19 KPI40480.1 - 2.9e-83 279.9 29.0 3.4e-83 279.7 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI40480.1 - 1.4e-24 86.4 46.3 1.1e-20 73.6 25.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rav1p_C PF12234.3 KPI40482.1 - 3.3e-48 164.3 0.0 6.8e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 KPI40482.1 - 0.0013 18.5 6.6 2.8 7.9 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat CTP_transf_1 PF01148.15 KPI40483.1 - 1.1e-21 77.6 5.7 5.1e-18 65.6 1.0 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family DUF3147 PF11345.3 KPI40483.1 - 0.0017 18.3 0.1 0.099 12.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3147) DUF3353 PF11833.3 KPI40483.1 - 0.41 10.0 3.1 6.4 6.1 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3353) Methyltransf_2 PF00891.13 KPI40484.1 - 2e-23 82.8 0.0 1.3e-21 76.9 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase MarR_2 PF12802.2 KPI40484.1 - 0.043 13.4 0.3 0.19 11.4 0.1 2.0 2 0 0 2 2 2 0 MarR family p450 PF00067.17 KPI40485.1 - 3.1e-61 207.3 0.0 3.2e-46 157.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF2156 PF09924.4 KPI40486.1 - 2e-31 108.9 0.0 2.8e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) UQ_con PF00179.21 KPI40487.1 - 9.9e-51 170.8 0.0 1.1e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KPI40487.1 - 1.4e-05 24.8 0.0 1.5e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KPI40487.1 - 0.041 13.7 0.0 0.072 12.9 0.0 1.6 1 1 0 1 1 1 0 RWD domain PAN_4 PF14295.1 KPI40488.1 - 0.0021 17.7 3.1 0.0021 17.7 2.2 2.8 2 0 0 2 2 2 1 PAN domain Asp PF00026.18 KPI40489.1 - 4.2e-53 180.6 0.0 5.3e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KPI40489.1 - 6.8e-08 32.6 0.1 2.8e-07 30.6 0.0 2.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 KPI40489.1 - 0.00011 21.9 0.0 0.59 10.0 0.0 3.0 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 KPI40489.1 - 0.00092 18.7 0.0 0.046 13.2 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Apc1 PF12859.2 KPI40490.1 - 6.9e-15 55.1 1.4 1.7e-14 53.9 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KPI40490.1 - 2.3e-08 33.8 5.5 0.00016 21.7 0.0 4.6 5 0 0 5 5 5 2 Proteasome/cyclosome repeat DUF3253 PF11625.3 KPI40491.1 - 1.5e-11 44.0 2.7 0.00011 22.0 0.0 3.4 3 1 0 3 3 3 2 Protein of unknown function (DUF3253) Glyco_hydro_61 PF03443.9 KPI40492.1 - 2.7e-68 230.0 0.0 3.9e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KPI40492.1 - 9.2e-12 44.4 12.1 9.2e-12 44.4 8.4 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain Rad60-SLD PF11976.3 KPI40493.1 - 1.6e-17 62.9 0.1 2.3e-17 62.4 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KPI40493.1 - 2.8e-05 23.4 0.0 4.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF342 PF03961.8 KPI40494.1 - 0.0049 15.3 1.6 0.0084 14.5 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF342) DUF501 PF04417.7 KPI40494.1 - 0.032 14.0 4.0 0.052 13.3 1.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF501) GAS PF13851.1 KPI40494.1 - 0.099 11.8 17.3 0.55 9.4 11.4 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 KPI40494.1 - 0.11 12.1 20.0 3.8 7.0 13.9 2.4 1 1 0 1 1 1 0 IncA protein HypA PF01155.14 KPI40494.1 - 0.17 11.5 0.8 0.38 10.4 0.5 1.5 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family APG6 PF04111.7 KPI40494.1 - 1 8.3 12.0 2.1 7.3 8.3 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 KPI40494.1 - 1.8 6.9 9.4 3 6.2 6.5 1.2 1 0 0 1 1 1 0 AAA domain DUF904 PF06005.7 KPI40494.1 - 2 8.7 22.5 2.5e+03 -1.2 15.6 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Mod_r PF07200.8 KPI40494.1 - 2.8 7.8 14.4 1.5 8.7 4.0 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF3450 PF11932.3 KPI40494.1 - 4.2 6.5 14.1 5.8 6.0 9.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) UPF0242 PF06785.6 KPI40494.1 - 7.4 5.1 11.7 11 4.6 8.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) TFIID-18kDa PF02269.11 KPI40495.1 - 6.2e-26 90.0 0.2 2.3e-25 88.2 0.0 1.9 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TLP-20 PF06088.6 KPI40495.1 - 1.1 8.9 4.5 1.6 8.3 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) NMT1 PF09084.6 KPI40496.1 - 4.8e-08 32.8 0.0 2e-07 30.8 0.0 1.8 1 1 1 2 2 2 1 NMT1/THI5 like NMT1_2 PF13379.1 KPI40496.1 - 3.2e-06 26.6 0.0 6.6e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.15 KPI40496.1 - 0.014 14.7 0.0 0.046 12.9 0.0 1.8 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 CorA PF01544.13 KPI40498.1 - 2.3e-17 63.0 1.1 4.1e-17 62.1 0.8 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TMEM171 PF15471.1 KPI40498.1 - 0.00019 20.3 0.1 0.00029 19.7 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein family 171 Glyco_tran_28_C PF04101.11 KPI40499.1 - 5.8e-14 52.0 0.2 2.9e-13 49.7 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KPI40499.1 - 0.00012 21.3 0.2 0.00035 19.8 0.0 1.7 1 1 0 2 2 2 1 Glycosyl transferase family 1 Glyco_trans_1_4 PF13692.1 KPI40499.1 - 0.041 14.0 0.0 0.078 13.1 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferases group 1 Methyltransf_6 PF03737.10 KPI40499.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Demethylmenaquinone methyltransferase UDPGT PF00201.13 KPI40499.1 - 0.12 10.9 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Ferritin_2 PF13668.1 KPI40501.1 - 9.8e-41 138.9 0.3 1.8e-40 138.0 0.2 1.4 1 0 0 1 1 1 1 Ferritin-like domain DUF455 PF04305.9 KPI40501.1 - 0.019 14.2 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF455) ADH_zinc_N PF00107.21 KPI40502.1 - 1.8e-07 30.7 0.0 2.9e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF3669 PF12417.3 KPI40504.1 - 9.1e-06 25.3 0.1 1.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Zinc finger protein F-box-like PF12937.2 KPI40505.1 - 0.013 15.1 0.6 0.44 10.3 0.1 2.6 2 0 0 2 2 2 0 F-box-like BTB PF00651.26 KPI40507.1 - 2.2e-12 46.9 0.0 7.9e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain DUF3227 PF11537.3 KPI40507.1 - 0.00021 21.3 0.0 0.6 10.2 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3227) HIF-1a_CTAD PF08778.5 KPI40508.1 - 0.068 12.6 1.2 0.19 11.2 0.1 2.1 2 0 0 2 2 2 0 HIF-1 alpha C terminal transactivation domain Big_2 PF02368.13 KPI40508.1 - 0.7 9.8 10.9 0.83 9.5 2.9 3.3 2 1 1 3 3 3 0 Bacterial Ig-like domain (group 2) Lge1 PF11488.3 KPI40509.1 - 0.0002 21.4 0.6 0.00036 20.6 0.4 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 Med8 PF10232.4 KPI40509.1 - 0.12 11.8 0.4 0.17 11.3 0.3 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF1388 PF07142.7 KPI40509.1 - 0.22 11.2 5.9 0.19 11.5 0.2 3.4 4 0 0 4 4 4 0 Repeat of unknown function (DUF1388) zf-CCCH PF00642.19 KPI40510.1 - 0.048 13.3 0.8 0.1 12.3 0.6 1.6 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NmrA PF05368.8 KPI40512.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family FA_desaturase PF00487.19 KPI40514.1 - 9.2e-30 103.9 24.6 1.4e-29 103.3 17.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KPI40514.1 - 0.044 13.8 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) p450 PF00067.17 KPI40515.1 - 1.1e-59 202.2 0.0 1.9e-59 201.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF2248 PF10005.4 KPI40516.1 - 0.11 11.3 0.1 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2248) NRPS PF08415.5 KPI40516.1 - 0.13 12.0 0.1 0.46 10.2 0.0 1.9 1 1 0 1 1 1 0 Nonribosomal peptide synthase Acetyltransf_7 PF13508.1 KPI40518.1 - 4.6e-08 33.0 0.0 1.4e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KPI40518.1 - 1.6e-06 28.0 0.0 4e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KPI40518.1 - 0.0034 17.5 0.0 0.011 15.8 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fungal_trans_2 PF11951.3 KPI40518.1 - 0.026 13.1 0.2 0.077 11.5 0.1 1.8 2 0 0 2 2 2 0 Fungal specific transcription factor domain DUF3439 PF11921.3 KPI40518.1 - 0.11 12.2 8.2 0.26 11.0 5.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PLAC8 PF04749.12 KPI40519.1 - 1.8e-25 89.5 14.1 2.2e-25 89.2 9.8 1.1 1 0 0 1 1 1 1 PLAC8 family DUF508 PF04370.7 KPI40520.1 - 0.39 10.3 2.7 0.94 9.0 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Acetyltransf_2 PF00797.12 KPI40521.1 - 5.2e-36 124.4 0.0 3.2e-35 121.8 0.0 1.9 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.14 KPI40521.1 - 0.1 12.8 0.1 0.39 10.9 0.1 1.9 2 0 0 2 2 2 0 Transglutaminase-like superfamily DUF2107 PF09880.4 KPI40522.1 - 3.4 7.6 7.0 0.73 9.7 0.7 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2107) PEP-utilizers PF00391.18 KPI40525.1 - 0.023 14.2 0.3 0.063 12.8 0.2 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain Sugar_tr PF00083.19 KPI40526.1 - 2.2e-65 221.0 10.4 7e-64 216.0 7.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI40526.1 - 6.4e-21 74.4 27.8 2.1e-19 69.4 9.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI40526.1 - 0.00034 19.1 8.2 0.021 13.2 0.2 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein PUCC PF03209.10 KPI40526.1 - 0.0023 16.6 0.1 0.0042 15.8 0.1 1.4 1 0 0 1 1 1 1 PUCC protein NB-ARC PF00931.17 KPI40527.1 - 5.3e-06 25.5 0.0 1.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 KPI40527.1 - 0.05 13.2 4.9 0.042 13.5 0.5 2.8 3 1 0 3 3 3 0 NACHT domain DUF1765 PF08578.5 KPI40528.1 - 7.4e-40 135.9 6.6 1.4e-39 134.9 4.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) MRP PF09387.5 KPI40528.1 - 0.021 14.5 6.1 0.029 14.1 0.9 2.5 1 1 0 2 2 2 0 Mitochondrial RNA binding protein MRP DUF3425 PF11905.3 KPI40529.1 - 1.5e-20 73.5 5.3 2.4e-19 69.5 2.7 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) CMS1 PF14617.1 KPI40530.1 - 1.8e-63 213.9 0.1 2.2e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 KPI40530.1 - 1.4e-06 27.8 0.0 1.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase HpaP PF09483.5 KPI40530.1 - 0.1 12.5 0.7 1.4 8.8 0.6 2.0 2 0 0 2 2 2 0 Type III secretion protein (HpaP) p450 PF00067.17 KPI40531.1 - 3.7e-61 207.0 0.0 4.5e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KPI40532.1 - 0.0017 18.1 2.0 0.0031 17.3 1.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1918 PF08940.6 KPI40532.1 - 0.021 14.1 0.1 0.1 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Zn_clus PF00172.13 KPI40533.1 - 3.4e-06 26.8 11.3 5.8e-06 26.1 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRP3 PF08572.5 KPI40536.1 - 1.6e-61 207.5 1.4 1.6e-61 207.5 1.0 1.8 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KPI40536.1 - 6.1e-37 126.1 0.9 1.2e-36 125.1 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) BLUF PF04940.7 KPI40536.1 - 0.087 12.5 0.1 2 8.1 0.0 3.1 3 0 0 3 3 3 0 Sensors of blue-light using FAD DUF2259 PF10016.4 KPI40536.1 - 0.25 11.0 3.5 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 Predicted secreted protein (DUF2259) F-box PF00646.28 KPI40537.1 - 5.8e-06 25.8 1.0 1.5e-05 24.5 0.7 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KPI40537.1 - 0.003 17.2 1.3 0.003 17.2 0.9 2.3 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KPI40537.1 - 0.048 13.3 0.3 0.067 12.9 0.2 1.6 1 1 0 1 1 1 0 F-box-like domain MFS_1 PF07690.11 KPI40538.1 - 3.1e-40 137.9 27.9 3.1e-40 137.9 19.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily 5_nucleotid_C PF02872.13 KPI40539.1 - 9.9e-22 77.5 0.0 9.8e-21 74.3 0.0 2.1 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KPI40539.1 - 3.2e-05 23.4 0.0 5.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KPI40539.1 - 0.0039 17.0 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_47 PF01532.15 KPI40541.1 - 3.2e-165 550.2 0.0 3.7e-165 549.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 4HBT PF03061.17 KPI40542.1 - 2.2e-12 46.9 0.0 3.5e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily RNase_H2-Ydr279 PF09468.5 KPI40543.1 - 6.1e-79 265.3 0.3 8.3e-79 264.9 0.2 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF2140 PF09911.4 KPI40543.1 - 0.14 11.3 0.2 0.32 10.1 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) MFS_1 PF07690.11 KPI40544.1 - 7.6e-23 80.7 19.4 7.6e-23 80.7 13.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KPI40544.1 - 0.0001 20.6 4.8 0.0001 20.6 3.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ACOX PF01756.14 KPI40545.1 - 2.2e-30 105.4 0.0 6.1e-30 103.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KPI40545.1 - 6.8e-21 74.8 1.4 6.8e-21 74.8 1.0 1.9 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KPI40545.1 - 3.7e-07 29.5 0.3 1.3e-06 27.8 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain MR_MLE_C PF13378.1 KPI40546.1 - 2e-18 66.3 1.2 3.4e-18 65.6 0.2 1.8 1 1 1 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KPI40546.1 - 4e-12 46.4 1.3 1.1e-11 45.1 0.2 2.2 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KPI40546.1 - 0.00029 20.8 0.1 0.0024 17.8 0.1 2.2 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain HATPase_c PF02518.21 KPI40547.1 - 3.5e-28 97.5 0.0 8e-28 96.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KPI40547.1 - 2.2e-23 82.4 0.1 4.8e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KPI40547.1 - 2.1e-15 56.4 0.0 6.9e-15 54.7 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 KPI40547.1 - 0.09 12.9 2.6 22 5.3 0.0 3.8 3 1 0 3 3 3 0 HAMP domain MFS_1 PF07690.11 KPI40549.1 - 1.6e-36 125.7 26.6 2.4e-35 121.8 18.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily XRN_N PF03159.13 KPI40550.1 - 2.5e-104 347.8 0.0 2.5e-104 347.8 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 KPI40550.1 - 0.0015 18.3 3.2 0.003 17.4 2.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 KPI40550.1 - 0.17 11.6 1.2 0.3 10.8 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Beta-lactamase PF00144.19 KPI40551.1 - 5.3e-31 107.8 2.2 2e-30 105.9 1.5 1.9 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KPI40551.1 - 0.24 10.6 0.0 0.37 10.0 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Reticulon PF02453.12 KPI40552.1 - 1.3e-34 119.1 4.0 1.8e-34 118.7 2.8 1.2 1 0 0 1 1 1 1 Reticulon DUF3080 PF11279.3 KPI40552.1 - 0.12 11.5 0.3 0.3 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3080) DAGK_prokar PF01219.14 KPI40552.1 - 0.27 10.8 2.5 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase VID27 PF08553.5 KPI40553.1 - 4.3e-285 948.0 5.8 1.3e-280 933.2 4.0 2.0 1 1 0 1 1 1 1 VID27 cytoplasmic protein Pro_isomerase PF00160.16 KPI40554.1 - 9.4e-45 152.5 0.5 1.4e-44 151.9 0.4 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KPI40554.1 - 1.3e-09 37.5 7.5 0.00017 21.1 0.7 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KPI40554.1 - 4.5e-06 26.1 11.3 4e-05 23.2 0.4 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KPI40554.1 - 5.3e-06 25.8 6.7 4.7e-05 22.8 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KPI40554.1 - 1.4e-05 25.6 5.1 0.0023 18.5 0.2 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KPI40554.1 - 0.00016 22.0 7.3 0.0008 19.8 0.6 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KPI40554.1 - 0.00019 21.2 4.2 0.0022 17.9 0.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KPI40554.1 - 0.0045 16.6 8.9 0.024 14.4 0.3 4.2 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KPI40554.1 - 0.0092 15.8 1.5 0.04 13.7 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KPI40554.1 - 0.033 14.6 2.9 0.56 10.7 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PilJ PF13675.1 KPI40554.1 - 0.34 11.2 2.8 7.3 6.9 0.1 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term TPR_19 PF14559.1 KPI40554.1 - 0.55 10.6 7.8 3 8.2 0.4 2.8 3 1 0 3 3 2 0 Tetratricopeptide repeat ADH_N PF08240.7 KPI40555.1 - 2e-29 101.5 2.7 2.7e-29 101.1 1.8 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain HEAT_2 PF13646.1 KPI40557.1 - 0.13 12.5 1.3 1.5 9.1 0.1 2.4 2 0 0 2 2 2 0 HEAT repeats DUF382 PF04037.8 KPI40558.1 - 2.2e-62 208.5 1.8 2.2e-62 208.5 1.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 KPI40558.1 - 2.9e-22 77.7 6.0 5.6e-22 76.8 4.2 1.5 1 0 0 1 1 1 1 PSP DUF3433 PF11915.3 KPI40559.1 - 7.1e-17 61.3 0.4 2.2e-16 59.7 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) DUF3900 PF13039.1 KPI40559.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3900) F-box-like PF12937.2 KPI40560.1 - 0.11 12.2 0.1 0.45 10.2 0.0 2.0 1 1 0 1 1 1 0 F-box-like DUF1993 PF09351.5 KPI40561.1 - 9.8e-49 165.3 0.0 1.1e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) AAA_25 PF13481.1 KPI40561.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Peptidase_C1_2 PF03051.10 KPI40562.1 - 5e-149 496.5 0.2 1.8e-118 395.8 0.0 2.0 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.18 KPI40562.1 - 2.5e-07 30.7 0.0 0.015 15.1 0.0 2.7 2 1 0 2 2 2 2 Papain family cysteine protease TGS PF02824.16 KPI40562.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 TGS domain Chitin_synth_1 PF01644.12 KPI40563.1 - 1.5e-81 272.0 0.2 2.2e-81 271.4 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KPI40563.1 - 1.2e-31 108.2 0.0 2.2e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KPI40563.1 - 8.9e-23 80.4 0.8 1.6e-17 63.1 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KPI40563.1 - 1.5e-09 37.8 9.5 1.6e-08 34.5 6.6 2.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KPI40563.1 - 1.9e-08 34.3 0.0 1.1e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 NAD_binding_2 PF03446.10 KPI40564.1 - 8.7e-34 116.7 0.0 1.2e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KPI40564.1 - 2.1e-18 66.5 0.0 3.1e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KPI40564.1 - 2.6e-05 24.5 0.0 0.00014 22.1 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 KPI40564.1 - 0.00031 19.6 0.0 0.00045 19.0 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family DBR1 PF05011.8 KPI40564.1 - 0.085 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain Sugar_tr PF00083.19 KPI40565.1 - 2.9e-52 177.7 22.2 5.3e-50 170.3 15.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI40565.1 - 4.5e-14 51.9 58.1 5.8e-12 44.9 21.2 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Het-C PF07217.6 KPI40566.1 - 9.9e-115 384.0 0.0 1.5e-114 383.4 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF4066 PF13278.1 KPI40567.1 - 2.6e-06 26.8 0.0 5.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KPI40567.1 - 0.0079 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4284 PF14112.1 KPI40567.1 - 0.15 12.5 0.4 0.28 11.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4284) zf-C2H2_2 PF12756.2 KPI40569.1 - 3.5e-06 27.0 3.7 4e-05 23.6 0.1 2.3 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KPI40569.1 - 0.00061 19.5 4.7 0.21 11.5 0.0 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI40569.1 - 0.0075 16.5 6.9 0.085 13.2 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KPI40569.1 - 0.0094 16.0 0.4 0.024 14.7 0.3 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KPI40569.1 - 0.13 12.0 1.2 7.9 6.3 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.1 KPI40569.1 - 1.3 9.5 10.8 1.6 9.2 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Sugar_tr PF00083.19 KPI40571.1 - 4.8e-20 71.5 26.4 2.5e-18 65.9 18.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Amb_V_allergen PF03913.8 KPI40572.1 - 0.17 11.6 5.3 2.1 8.1 2.8 3.1 3 1 0 3 3 3 0 Amb V Allergen Abhydrolase_6 PF12697.2 KPI40573.1 - 1.1e-21 77.8 0.1 1.3e-21 77.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI40573.1 - 8.8e-06 25.5 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KPI40573.1 - 0.00071 19.8 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Fungal_trans_2 PF11951.3 KPI40574.1 - 0.042 12.4 0.0 0.042 12.4 0.0 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain DUF4095 PF13338.1 KPI40575.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4095) BTB PF00651.26 KPI40576.1 - 4.9e-05 23.2 0.0 7.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Asp_protease_2 PF13650.1 KPI40577.1 - 1.1e-07 32.2 0.1 0.00044 20.6 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease RVP PF00077.15 KPI40577.1 - 0.0012 18.7 0.0 0.14 12.0 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease DUF1758 PF05585.7 KPI40577.1 - 0.0054 16.3 0.7 0.99 8.9 0.0 3.1 2 1 1 3 3 3 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.1 KPI40577.1 - 0.019 14.7 0.1 0.4 10.5 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease MFS_1 PF07690.11 KPI40579.1 - 1.3e-24 86.5 28.9 1.3e-24 86.5 20.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3609 PF12259.3 KPI40579.1 - 0.021 13.4 0.0 0.044 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) DUF912 PF06024.7 KPI40579.1 - 0.046 13.7 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Glyco_hydro_2 PF00703.16 KPI40580.1 - 4.5e-07 30.2 0.1 1.7e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KPI40580.1 - 9.6e-06 25.2 0.1 2.8e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KPI40580.1 - 4.2e-05 22.5 0.0 9.4e-05 21.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Vps51 PF08700.6 KPI40581.1 - 1.9e-20 72.5 0.0 3.5e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 KPI40581.1 - 0.044 12.2 0.0 0.059 11.8 0.0 1.1 1 0 0 1 1 1 0 Dor1-like family Fes1 PF08609.5 KPI40581.1 - 0.076 13.5 0.0 0.81 10.2 0.0 2.3 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 Ist1 PF03398.9 KPI40582.1 - 1.6e-51 173.9 1.9 2e-51 173.6 1.3 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway GFA PF04828.9 KPI40583.1 - 1.7e-05 24.6 2.0 0.13 12.1 0.0 2.7 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme dCMP_cyt_deam_1 PF00383.17 KPI40584.1 - 0.00039 20.0 0.0 0.00084 18.9 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DAO PF01266.19 KPI40585.1 - 3.2e-32 111.8 1.8 2.2e-17 62.9 0.0 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase MFS_1 PF07690.11 KPI40586.1 - 5e-34 117.5 17.9 5e-34 117.5 12.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 KPI40586.1 - 0.038 14.3 3.5 0.24 11.8 0.2 2.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2410 PF10307.4 KPI40587.1 - 9.2e-67 224.2 0.0 1.7e-66 223.3 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) OmpH PF03938.9 KPI40588.1 - 0.0003 20.7 4.6 0.0003 20.7 3.2 1.8 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) IncA PF04156.9 KPI40588.1 - 0.0041 16.7 0.7 0.0055 16.3 0.5 1.3 1 0 0 1 1 1 1 IncA protein BLOC1_2 PF10046.4 KPI40588.1 - 0.006 16.6 0.9 0.011 15.9 0.6 1.4 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.3 KPI40588.1 - 0.013 14.7 0.4 0.013 14.7 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) GATA PF00320.22 KPI40588.1 - 0.022 14.0 4.8 0.042 13.2 3.4 1.4 1 0 0 1 1 1 0 GATA zinc finger Methyltransf_18 PF12847.2 KPI40588.1 - 0.023 15.2 0.1 0.68 10.5 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain MAD PF05557.8 KPI40588.1 - 0.027 12.6 4.3 0.046 11.8 3.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein TSC22 PF01166.13 KPI40588.1 - 0.031 14.2 1.9 0.031 14.2 1.3 3.0 4 1 0 5 5 2 0 TSC-22/dip/bun family CDC37_N PF03234.9 KPI40588.1 - 0.033 14.5 0.2 0.063 13.6 0.1 1.5 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Zn-ribbon_8 PF09723.5 KPI40588.1 - 0.034 14.0 0.5 0.072 13.0 0.3 1.5 1 0 0 1 1 1 0 Zinc ribbon domain DUF972 PF06156.8 KPI40588.1 - 0.052 13.8 4.2 0.087 13.1 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 KPI40588.1 - 0.097 12.9 6.2 0.47 10.7 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Fmp27_WPPW PF10359.4 KPI40588.1 - 0.12 10.7 2.0 0.22 9.8 1.4 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Seryl_tRNA_N PF02403.17 KPI40588.1 - 0.27 11.2 4.2 0.51 10.3 1.7 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MCC-bdg_PDZ PF10506.4 KPI40588.1 - 1 9.2 7.0 0.16 11.7 1.5 2.2 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DivIC PF04977.10 KPI40588.1 - 6.4 6.3 12.9 0.68 9.4 4.5 2.4 2 1 1 3 3 3 0 Septum formation initiator Cupin_8 PF13621.1 KPI40589.1 - 2.4e-37 128.8 0.0 3.7e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KPI40589.1 - 8.8e-08 31.7 0.2 7.1e-06 25.4 0.0 2.6 3 0 0 3 3 3 2 Cupin superfamily protein JmjC PF02373.17 KPI40589.1 - 7.3e-05 22.9 0.0 0.00024 21.3 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 KPI40589.1 - 0.065 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Cupin domain Iso_dh PF00180.15 KPI40590.1 - 2e-68 230.8 0.0 2.5e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Opy2 PF09463.5 KPI40592.1 - 1.3e-11 44.3 21.1 2e-11 43.7 14.6 1.3 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.15 KPI40592.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.10 KPI40592.1 - 0.095 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MFS_1 PF07690.11 KPI40593.1 - 0.011 14.4 12.0 0.26 9.9 7.7 2.0 2 0 0 2 2 2 0 Major Facilitator Superfamily MFS_1 PF07690.11 KPI40594.1 - 2.2e-24 85.8 65.9 1.9e-17 63.0 24.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KPI40594.1 - 0.22 9.9 22.8 0.014 13.8 9.5 3.0 1 1 1 3 3 3 0 Vacuole effluxer Atg22 like DUF1290 PF06947.7 KPI40594.1 - 0.22 11.4 0.2 0.22 11.4 0.1 3.5 2 1 1 4 4 4 0 Protein of unknown function (DUF1290) FOLN PF09289.5 KPI40595.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain RTA1 PF04479.8 KPI40597.1 - 5.8e-42 143.6 9.1 7.6e-42 143.3 6.3 1.1 1 0 0 1 1 1 1 RTA1 like protein Poxvirus_B22R_C PF13168.1 KPI40597.1 - 0.089 12.0 0.7 0.15 11.2 0.5 1.3 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal MFS_1 PF07690.11 KPI40598.1 - 4.4e-27 94.7 31.4 1.1e-26 93.3 21.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI40598.1 - 8.6e-05 21.2 13.4 8.6e-05 21.2 9.3 1.7 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 KPI40598.1 - 0.0033 15.5 1.9 0.0039 15.3 0.7 1.5 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.23 KPI40600.1 - 1.4e-77 260.8 0.0 1.9e-77 260.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ECH PF00378.15 KPI40600.1 - 1.1e-45 155.6 0.0 1.8e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family AMP-binding_C PF13193.1 KPI40600.1 - 0.0002 22.2 0.9 0.0016 19.3 0.0 2.7 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.13 KPI40601.1 - 1.4e-07 31.2 13.3 3.7e-07 29.9 9.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.4 KPI40601.1 - 1.8 8.6 7.4 3.5 7.6 5.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) AA_permease PF00324.16 KPI40602.1 - 1.1e-116 390.0 39.3 1.3e-116 389.7 27.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI40602.1 - 6.6e-32 110.5 43.2 8.8e-32 110.1 29.9 1.1 1 0 0 1 1 1 1 Amino acid permease GMC_oxred_N PF00732.14 KPI40603.1 - 1.1e-62 211.8 0.0 1.7e-62 211.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI40603.1 - 2.4e-30 105.7 0.0 4.2e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KPI40603.1 - 0.001 18.0 0.1 0.0015 17.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KPI40603.1 - 0.0097 14.7 0.0 3.2 6.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain F-box-like PF12937.2 KPI40604.1 - 0.017 14.8 0.0 0.09 12.5 0.0 2.1 1 1 0 1 1 1 0 F-box-like Not3 PF04065.10 KPI40605.1 - 1e-70 237.6 25.3 1.6e-70 237.0 17.5 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KPI40605.1 - 2.5e-41 140.7 11.7 2.5e-41 140.7 8.1 1.9 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 KPI40605.1 - 0.014 14.9 3.5 0.041 13.4 2.4 1.8 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Syntaxin PF00804.20 KPI40605.1 - 1.6 8.9 15.5 25 5.0 10.7 2.6 1 1 0 1 1 1 0 Syntaxin LMWPc PF01451.16 KPI40606.1 - 6.2e-35 120.5 0.0 7.1e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase PrmA PF06325.8 KPI40608.1 - 1.5e-11 43.9 0.0 3.8e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KPI40608.1 - 2e-10 40.4 0.0 4.5e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI40608.1 - 3.9e-09 36.8 0.0 1.5e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI40608.1 - 7.7e-09 36.1 0.0 2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KPI40608.1 - 1.2e-07 31.2 0.1 2.6e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KPI40608.1 - 1.2e-07 31.7 0.0 3.5e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 KPI40608.1 - 1.7e-06 27.7 0.1 3.6e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.1 KPI40608.1 - 1.1e-05 25.7 0.1 3.5e-05 24.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI40608.1 - 1.1e-05 25.2 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI40608.1 - 0.00044 20.6 0.0 0.001 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KPI40608.1 - 0.0012 18.4 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 KPI40608.1 - 0.0021 17.5 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.6 KPI40608.1 - 0.0022 16.7 0.0 0.0039 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.14 KPI40608.1 - 0.0051 16.8 0.1 0.013 15.5 0.0 1.6 2 0 0 2 2 1 1 FtsJ-like methyltransferase TehB PF03848.9 KPI40608.1 - 0.033 13.3 0.1 0.073 12.2 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 KPI40608.1 - 0.046 14.5 0.0 0.22 12.3 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.11 KPI40608.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase UPF0020 PF01170.13 KPI40608.1 - 0.13 11.7 0.1 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Amidase PF01425.16 KPI40609.1 - 2.3e-28 99.2 1.9 2.3e-28 99.2 1.3 3.3 2 1 2 4 4 4 1 Amidase CFEM PF05730.6 KPI40610.1 - 7.1e-09 35.3 11.0 1.1e-08 34.7 7.6 1.3 1 0 0 1 1 1 1 CFEM domain Podoplanin PF05808.6 KPI40610.1 - 0.00027 20.5 0.9 0.00086 18.9 0.1 2.2 2 0 0 2 2 2 1 Podoplanin SKG6 PF08693.5 KPI40610.1 - 0.01 15.1 0.5 0.021 14.1 0.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CoA_trans PF01144.18 KPI40611.1 - 7.5e-93 309.6 1.2 2.8e-55 186.8 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KPI40611.1 - 2.6e-06 27.1 0.1 5.3e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain PA PF02225.17 KPI40611.1 - 0.05 13.3 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 PA domain SSP160 PF06933.6 KPI40612.1 - 0.06 11.3 15.3 0.074 11.0 10.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Gly-zipper_OmpA PF13436.1 KPI40612.1 - 0.17 11.5 1.7 0.31 10.6 1.1 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Dicty_REP PF05086.7 KPI40612.1 - 2 6.0 3.7 2.5 5.7 2.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cupin_2 PF07883.6 KPI40614.1 - 1e-08 34.5 0.0 1.7e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KPI40614.1 - 0.008 15.5 0.0 0.017 14.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) HMG_box PF00505.14 KPI40616.1 - 9.4e-22 77.0 0.5 1.8e-21 76.1 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KPI40616.1 - 2.8e-06 27.6 0.7 6.2e-06 26.4 0.2 1.8 2 0 0 2 2 2 1 HMG-box domain HMGL-like PF00682.14 KPI40617.1 - 4.2e-29 101.8 0.0 5.9e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 HMGL-like MFS_1 PF07690.11 KPI40618.1 - 3.1e-29 101.7 30.1 3.1e-29 101.7 20.8 1.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Complex1_LYR_2 PF13233.1 KPI40619.1 - 7.5e-19 68.1 0.0 1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KPI40619.1 - 0.0025 17.5 0.2 0.0034 17.1 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KPI40619.1 - 0.025 14.7 0.2 0.035 14.3 0.2 1.4 1 0 0 1 1 1 0 Complex1_LYR-like GluR_Homer-bdg PF10606.4 KPI40619.1 - 0.04 13.8 0.4 0.066 13.1 0.3 1.3 1 0 0 1 1 1 0 Homer-binding domain of metabotropic glutamate receptor BTB PF00651.26 KPI40620.1 - 1e-09 38.3 0.0 2.3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain SNN_linker PF09050.5 KPI40621.1 - 1.1 8.9 7.6 2.5 7.6 5.3 1.6 1 0 0 1 1 1 0 Stannin unstructured linker B12D PF06522.6 KPI40623.1 - 0.00013 21.5 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF1212 PF06738.7 KPI40623.1 - 0.15 11.5 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Methyltransf_16 PF10294.4 KPI40624.1 - 1.1e-19 70.4 0.0 1.6e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KPI40624.1 - 0.00012 21.7 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI40624.1 - 0.00022 21.7 0.0 0.0004 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KPI40624.1 - 0.00043 19.5 0.0 0.00061 19.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 KPI40624.1 - 0.00082 18.8 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 KPI40624.1 - 0.014 15.8 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KPI40624.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KPI40624.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Sod_Fe_C PF02777.13 KPI40625.1 - 1.3e-38 131.0 0.3 2.4e-38 130.2 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KPI40625.1 - 4.2e-29 100.6 1.6 7.4e-29 99.8 1.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Imm15 PF15590.1 KPI40625.1 - 2.4 7.2 6.1 2 7.5 0.1 3.2 2 2 2 4 4 4 0 Immunity protein 15 Trp_syntA PF00290.15 KPI40626.1 - 7.6e-86 286.8 0.0 1.3e-85 286.1 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 KPI40626.1 - 2.1e-43 148.6 0.4 3.7e-43 147.9 0.3 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme STN PF07660.9 KPI40626.1 - 0.88 9.1 2.6 5.5 6.6 0.1 2.9 3 0 0 3 3 3 0 Secretin and TonB N terminus short domain IBN_N PF03810.14 KPI40627.1 - 6.2e-13 48.4 3.0 2e-11 43.6 0.0 3.9 5 0 0 5 5 5 1 Importin-beta N-terminal domain Cse1 PF08506.5 KPI40627.1 - 8.9e-10 37.6 0.1 8.3e-09 34.4 0.0 2.2 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.7 KPI40627.1 - 1e-05 25.4 0.1 0.0069 16.2 0.0 3.2 2 0 0 2 2 2 2 Exportin 1-like protein CutC PF03932.9 KPI40627.1 - 0.16 11.2 0.1 12 5.1 0.0 2.5 3 0 0 3 3 3 0 CutC family Fungal_trans PF04082.13 KPI40628.1 - 5.7e-12 45.0 0.9 8.9e-12 44.4 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rab3-GTPase_cat PF13890.1 KPI40628.1 - 0.051 12.9 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit DUF3425 PF11905.3 KPI40630.1 - 6e-12 45.6 0.0 8.7e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Vezatin PF12632.2 KPI40631.1 - 3.5e-24 85.2 0.4 4.5e-24 84.8 0.2 1.1 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes MCP_N PF05581.7 KPI40631.1 - 0.2 11.8 0.6 1.6 8.8 0.1 2.6 3 0 0 3 3 3 0 Vibrio chemotaxis protein N terminus p450 PF00067.17 KPI40632.1 - 4.2e-49 167.3 0.0 4.8e-40 137.4 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 DUF1295 PF06966.7 KPI40633.1 - 1.8e-42 145.2 0.2 9.7e-41 139.5 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KPI40633.1 - 0.0012 18.9 0.0 0.01 15.8 0.0 2.3 1 1 1 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 KPI40633.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 KPI40633.1 - 0.02 15.0 0.0 0.084 13.0 0.0 2.1 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family MFS_1 PF07690.11 KPI40635.1 - 6.3e-20 71.1 21.0 1.4e-19 70.0 14.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI40635.1 - 6.8e-07 28.2 4.0 6.8e-07 28.2 2.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Tropomyosin_1 PF12718.2 KPI40636.1 - 0.001 18.9 16.5 0.0023 17.8 11.5 1.6 1 0 0 1 1 1 1 Tropomyosin like HALZ PF02183.13 KPI40636.1 - 0.51 10.1 3.8 0.73 9.5 0.7 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper V_ATPase_I PF01496.14 KPI40636.1 - 1.1 7.0 6.6 1.8 6.3 4.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Myosin_tail_1 PF01576.14 KPI40636.1 - 1.7 6.2 23.3 0.022 12.5 7.8 2.0 1 1 0 2 2 2 0 Myosin tail DUF3573 PF12097.3 KPI40636.1 - 2.9 6.4 3.8 4.9 5.6 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) HALZ PF02183.13 KPI40637.1 - 0.00016 21.3 8.4 0.00027 20.5 0.3 2.7 3 0 0 3 3 3 1 Homeobox associated leucine zipper bZIP_1 PF00170.16 KPI40637.1 - 0.00024 20.9 7.8 0.023 14.6 0.4 2.7 2 0 0 2 2 2 2 bZIP transcription factor Nup54 PF13874.1 KPI40637.1 - 0.0023 17.5 2.0 0.0043 16.7 1.4 1.5 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 DivIC PF04977.10 KPI40637.1 - 0.015 14.7 3.2 1.5 8.3 0.2 2.8 2 0 0 2 2 2 0 Septum formation initiator DUF2205 PF10224.4 KPI40637.1 - 0.016 14.7 0.7 4.1 7.0 0.1 2.5 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) BLOC1_2 PF10046.4 KPI40637.1 - 0.055 13.5 1.5 0.22 11.6 0.3 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TSC22 PF01166.13 KPI40637.1 - 0.087 12.8 0.2 0.087 12.8 0.2 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family Shugoshin_N PF07558.6 KPI40637.1 - 0.12 12.1 3.0 0.18 11.5 0.4 2.4 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF904 PF06005.7 KPI40637.1 - 0.13 12.5 7.6 4.1 7.7 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF972 PF06156.8 KPI40637.1 - 0.16 12.2 0.3 0.16 12.2 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Prefoldin_2 PF01920.15 KPI40637.1 - 0.21 11.3 3.4 0.7 9.6 0.4 2.3 2 0 0 2 2 2 0 Prefoldin subunit TMF_DNA_bd PF12329.3 KPI40637.1 - 0.42 10.4 6.1 5.8 6.7 2.2 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 KPI40637.1 - 0.9 9.3 11.5 0.2 11.4 5.1 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) IncA PF04156.9 KPI40637.1 - 1.4 8.4 5.5 2.4 7.6 3.8 1.4 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 KPI40637.1 - 7.7 6.4 14.0 1.9 8.3 0.1 3.0 3 0 0 3 3 2 0 Basic region leucine zipper Tropomyosin_1 PF12718.2 KPI40637.1 - 8.9 6.1 15.0 0.2 11.5 4.8 2.4 3 1 0 3 3 3 0 Tropomyosin like Bud13 PF09736.4 KPI40638.1 - 7 6.9 8.5 16 5.7 5.9 1.7 1 1 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex MFS_1 PF07690.11 KPI40639.1 - 3.2e-19 68.8 27.2 3.2e-19 68.8 18.8 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI40639.1 - 0.018 13.6 31.9 0.058 11.9 10.8 2.9 2 2 1 3 3 3 0 Sugar (and other) transporter Gemini_mov PF01708.11 KPI40639.1 - 1.4 8.5 4.8 0.27 10.8 0.5 2.0 2 0 0 2 2 2 0 Geminivirus putative movement protein GFO_IDH_MocA PF01408.17 KPI40640.1 - 3.5e-18 66.2 0.0 5.4e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold FYVE PF01363.16 KPI40641.1 - 2.7e-23 81.6 21.4 4.8e-17 61.6 2.2 3.0 3 0 0 3 3 3 2 FYVE zinc finger zf-Di19 PF05605.7 KPI40641.1 - 0.00017 21.6 9.7 0.036 14.2 0.1 2.8 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.11 KPI40641.1 - 0.0023 17.7 5.9 0.0023 17.7 4.1 3.8 3 1 1 4 4 4 1 AN1-like Zinc finger zf-C2H2_2 PF12756.2 KPI40641.1 - 0.0039 17.2 5.9 0.07 13.2 0.0 3.1 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-RING_3 PF14369.1 KPI40641.1 - 0.031 14.2 3.3 3.7 7.6 0.0 3.3 3 0 0 3 3 3 0 zinc-finger Rbsn PF11464.3 KPI40641.1 - 0.078 12.5 0.3 0.078 12.5 0.2 2.3 2 0 0 2 2 2 0 Rabenosyn Rab binding domain FYVE_2 PF02318.11 KPI40641.1 - 0.27 11.1 11.6 0.14 12.0 0.5 3.5 3 0 0 3 3 3 0 FYVE-type zinc finger IBR PF01485.16 KPI40641.1 - 8.3 6.3 18.1 1 9.2 1.6 3.3 4 0 0 4 4 4 0 IBR domain Rxt3 PF08642.5 KPI40642.1 - 7.9e-21 74.4 0.0 1.8e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 KPI40642.1 - 7e-06 25.9 0.0 0.00017 21.4 0.0 2.4 1 1 0 1 1 1 1 LCCL domain HET PF06985.6 KPI40643.1 - 3.7e-30 104.9 0.7 7e-30 104.0 0.5 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clr2 PF10383.4 KPI40643.1 - 0.0077 16.2 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 SAPS PF04499.10 KPI40644.1 - 5.6e-71 239.6 0.1 5.6e-71 239.6 0.1 1.9 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein Ribonuclease_T2 PF00445.13 KPI40645.1 - 1e-28 100.2 0.1 1.7e-28 99.5 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family FMO-like PF00743.14 KPI40645.1 - 0.16 10.1 0.2 0.23 9.6 0.2 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_binding_10 PF13460.1 KPI40647.1 - 0.00021 21.3 0.0 0.00037 20.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI40647.1 - 0.0031 16.9 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KPI40647.1 - 0.015 14.2 0.0 3.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein V-SNARE_C PF12352.3 KPI40650.1 - 1.2e-17 63.6 2.8 1.2e-17 63.6 1.9 2.9 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 KPI40650.1 - 4.1e-15 55.6 4.8 4.3e-15 55.6 2.1 2.0 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Histone_HNS PF00816.16 KPI40650.1 - 0.0084 16.5 0.6 0.023 15.2 0.5 1.7 1 0 0 1 1 1 1 H-NS histone family TBCA PF02970.11 KPI40650.1 - 0.027 14.5 3.2 1.8 8.7 0.1 3.2 2 1 2 4 4 4 0 Tubulin binding cofactor A PilJ PF13675.1 KPI40650.1 - 0.029 14.6 12.1 0.037 14.3 1.2 2.5 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Dor1 PF04124.7 KPI40650.1 - 0.049 12.0 2.7 0.1 11.0 1.9 1.4 1 0 0 1 1 1 0 Dor1-like family Sec20 PF03908.8 KPI40650.1 - 0.12 12.0 3.6 1.9 8.2 0.0 2.8 2 1 0 2 2 2 0 Sec20 DUF1759 PF03564.10 KPI40650.1 - 0.14 11.9 2.4 0.17 11.6 0.4 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) FIVAR PF07554.8 KPI40650.1 - 0.25 11.6 1.5 1 9.6 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised Sugar-binding Domain FlxA PF14282.1 KPI40650.1 - 4.1 7.4 7.7 10 6.1 1.8 2.6 1 1 1 2 2 2 0 FlxA-like protein DUF4407 PF14362.1 KPI40650.1 - 5.9 5.7 8.6 7.4 5.4 5.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3500 PF12006.3 KPI40651.1 - 4.2e-71 239.4 0.0 1.8e-50 171.6 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3500) Glyco_hydro_81 PF03639.8 KPI40652.1 - 3.6e-193 643.3 6.7 5e-193 642.9 4.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Utp14 PF04615.8 KPI40652.1 - 3.7e-168 561.0 56.0 3.7e-168 561.0 38.8 3.1 1 1 1 2 2 2 1 Utp14 protein DUF4203 PF13886.1 KPI40652.1 - 3.5 7.0 4.9 6.4 6.1 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Alpha-amylase PF00128.19 KPI40653.1 - 4.5e-24 85.4 0.0 1.6e-23 83.6 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF3688 PF12461.3 KPI40653.1 - 0.0028 17.9 0.2 0.0069 16.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3688) Glyco_hydro_70 PF02324.11 KPI40653.1 - 0.0051 14.6 0.0 3.9 5.0 0.0 3.2 4 0 0 4 4 4 2 Glycosyl hydrolase family 70 DUF1992 PF09350.5 KPI40654.1 - 1.2e-24 85.9 2.3 3.4e-24 84.4 0.2 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1992) AMP-binding_C_2 PF14535.1 KPI40654.1 - 0.043 13.8 1.8 0.24 11.4 0.0 3.0 4 0 0 4 4 4 0 AMP-binding enzyme C-terminal domain Sulfate_transp PF00916.15 KPI40656.1 - 6.2e-51 173.0 3.0 6.2e-51 173.0 2.1 2.0 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KPI40656.1 - 1e-28 98.8 3.3 1e-28 98.8 2.3 2.5 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KPI40656.1 - 1.6e-16 59.7 0.0 3.2e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KPI40656.1 - 1.3e-05 25.0 0.0 0.00023 21.1 0.0 2.6 2 1 0 2 2 2 1 STAS domain Serinc PF03348.10 KPI40657.1 - 2.9e-154 513.9 12.2 3.3e-154 513.7 8.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Pyr_redox_3 PF13738.1 KPI40658.1 - 2.4e-19 70.2 0.0 4.9e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI40658.1 - 7.2e-19 67.3 0.0 1.8e-18 66.0 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI40658.1 - 9.5e-09 35.1 0.0 2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI40658.1 - 2.9e-06 26.4 0.0 0.00016 20.7 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KPI40658.1 - 4.1e-05 23.5 0.0 6.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI40658.1 - 0.0035 17.1 0.0 0.018 14.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FCD PF07729.7 KPI40658.1 - 0.21 11.8 0.3 0.43 10.8 0.0 1.6 2 0 0 2 2 2 0 FCD domain Choline_transpo PF04515.7 KPI40659.1 - 9.6e-103 343.4 22.2 9.6e-103 343.4 15.4 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.8 KPI40659.1 - 1.6 8.8 7.5 9.5 6.2 5.2 2.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_hydro_72 PF03198.9 KPI40660.1 - 4.3e-134 446.4 5.2 5.4e-134 446.1 3.6 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KPI40660.1 - 1.7e-09 37.3 0.5 4.4e-09 35.9 0.4 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-C2H2_4 PF13894.1 KPI40661.1 - 0.092 13.1 0.8 0.29 11.5 0.6 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger GYF PF02213.11 KPI40662.1 - 4e-14 51.9 0.1 8.3e-14 50.9 0.1 1.6 1 0 0 1 1 1 1 GYF domain TPR_MLP1_2 PF07926.7 KPI40663.1 - 1.1e-27 96.4 26.1 1.1e-27 96.4 18.1 17.6 4 4 12 17 17 17 7 TPR/MLP1/MLP2-like protein YkuD PF03734.9 KPI40663.1 - 0.017 15.4 0.0 0.055 13.7 0.0 1.8 2 0 0 2 2 2 0 L,D-transpeptidase catalytic domain Reticulon PF02453.12 KPI40663.1 - 0.65 9.5 0.9 2.5 7.6 0.1 2.4 2 0 0 2 2 2 0 Reticulon KH_1 PF00013.24 KPI40664.1 - 8.7e-44 146.9 7.2 1.8e-14 53.1 0.9 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KPI40664.1 - 6.2e-31 105.4 11.9 2.6e-10 39.7 1.2 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KPI40664.1 - 5.5e-11 41.8 1.3 0.048 13.2 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KPI40664.1 - 4e-08 32.7 3.8 0.059 13.0 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KPI40664.1 - 0.0011 18.7 1.1 2 8.2 0.0 3.3 3 0 0 3 3 3 1 NusA-like KH domain DUF802 PF05650.6 KPI40664.1 - 9.9 6.3 8.8 2.8 8.1 2.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF802) Abhydrolase_6 PF12697.2 KPI40665.1 - 4.7e-26 92.0 2.9 5.8e-26 91.7 2.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI40665.1 - 6.4e-11 42.1 0.0 1.4e-10 41.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KPI40665.1 - 0.0032 17.2 0.0 0.021 14.6 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase DUF2305 PF10230.4 KPI40665.1 - 0.0078 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_1 PF00561.15 KPI40665.1 - 0.015 14.9 0.0 3.4 7.1 0.0 2.7 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF1168 PF06658.7 KPI40666.1 - 2.2e-39 134.2 18.2 3.1e-39 133.7 12.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) CAF-1_p150 PF11600.3 KPI40666.1 - 0.033 13.5 17.0 0.045 13.1 11.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RNase_H2-Ydr279 PF09468.5 KPI40666.1 - 0.26 10.4 5.5 0.32 10.1 3.8 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Hex_IIIa PF02455.11 KPI40666.1 - 2.5 6.7 6.5 3 6.4 4.5 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF4407 PF14362.1 KPI40666.1 - 7.5 5.4 7.8 9.3 5.1 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ldh_1_N PF00056.18 KPI40667.1 - 4.5e-44 149.6 0.1 6.7e-44 149.1 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KPI40667.1 - 2.5e-38 131.5 0.1 7.9e-38 129.9 0.1 1.8 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KPI40667.1 - 0.012 14.3 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KPI40667.1 - 0.026 14.7 1.2 0.077 13.3 0.0 2.3 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KPI40667.1 - 0.056 13.3 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_4 PF02056.11 KPI40667.1 - 0.14 11.4 2.5 0.47 9.7 0.2 2.4 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase Methyltransf_16 PF10294.4 KPI40668.1 - 2.2e-18 66.3 0.0 2.9e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Aldedh PF00171.17 KPI40669.1 - 8.2e-120 400.2 0.0 9.5e-120 400.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.13 KPI40670.1 - 5.2e-20 71.4 0.1 1.1e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.1 KPI40671.1 - 0.00065 19.7 0.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 2 NADH(P)-binding CH PF00307.26 KPI40672.1 - 2.8e-06 27.3 0.0 0.13 12.3 0.0 3.4 2 1 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KPI40672.1 - 0.00071 19.1 0.0 1.8 8.2 0.0 2.9 3 0 0 3 3 3 2 CAMSAP CH domain IQ PF00612.22 KPI40672.1 - 0.0082 15.6 1.2 0.022 14.3 0.8 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif PI3_PI4_kinase PF00454.22 KPI40673.1 - 9.3e-37 126.7 0.0 1.5e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3328 PF11807.3 KPI40674.1 - 1.9e-51 174.8 0.1 2.3e-51 174.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Complex1_LYR PF05347.10 KPI40676.1 - 2.2e-05 24.1 3.0 3.3e-05 23.6 0.7 2.3 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KPI40676.1 - 0.0003 20.9 0.6 0.0003 20.9 0.4 2.4 3 0 0 3 3 3 1 Complex1_LYR-like V-SNARE_C PF12352.3 KPI40677.1 - 4.4e-13 49.0 0.2 8.9e-13 48.1 0.2 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KPI40677.1 - 0.0046 16.6 0.0 0.017 14.8 0.0 1.8 2 0 0 2 2 2 1 Sec20 Sigma70_r4 PF04545.11 KPI40677.1 - 0.11 11.8 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 SDH_alpha PF03313.10 KPI40677.1 - 0.18 10.7 0.8 0.33 9.9 0.2 1.6 2 0 0 2 2 2 0 Serine dehydratase alpha chain Acyl-CoA_dh_2 PF08028.6 KPI40678.1 - 7e-21 74.8 0.6 1.1e-20 74.2 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KPI40678.1 - 1.3e-07 32.2 0.0 3.2e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 KPI40678.1 - 4.2e-05 23.6 0.1 7.9e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain COQ7 PF03232.8 KPI40679.1 - 8.3 5.8 12.4 0.027 13.9 2.1 1.5 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 DUF726 PF05277.7 KPI40680.1 - 4e-97 325.1 1.0 4.2e-94 315.2 0.0 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF726) Thioesterase PF00975.15 KPI40680.1 - 0.00096 19.4 0.0 0.00096 19.4 0.0 2.5 2 1 1 3 3 3 1 Thioesterase domain Abhydrolase_6 PF12697.2 KPI40680.1 - 0.0086 15.9 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 KPI40681.1 - 1.4e-78 256.1 15.9 3.2e-12 45.8 0.7 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KPI40681.1 - 1.4e-06 26.7 4.4 0.001 17.3 0.1 3.8 4 1 0 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KPI40681.1 - 0.00022 20.0 0.0 1 8.0 0.0 3.4 2 1 1 3 3 3 2 Nup133 N terminal like bZIP_2 PF07716.10 KPI40681.1 - 0.15 11.9 0.2 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Gram_pos_anchor PF00746.16 KPI40682.1 - 0.052 13.3 0.2 0.076 12.8 0.1 1.3 1 0 0 1 1 1 0 Gram positive anchor AMP-binding PF00501.23 KPI40683.1 - 9.6e-38 129.6 0.0 1.1e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI40683.1 - 4.1e-12 46.8 0.0 7.3e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LisH PF08513.6 KPI40685.1 - 8.3e-08 31.7 0.1 1.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 LisH WD40 PF00400.27 KPI40685.1 - 1.6e-07 30.9 6.7 0.0096 15.7 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 KPI40685.1 - 0.031 13.9 0.1 0.55 9.9 0.0 2.8 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A adh_short PF00106.20 KPI40686.1 - 3.4e-09 36.8 0.1 3.4e-09 36.8 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KPI40686.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 KR domain COPIIcoated_ERV PF07970.7 KPI40687.1 - 2e-33 115.8 1.0 3.4e-19 69.3 0.1 2.3 2 0 0 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KPI40687.1 - 4.5e-23 81.0 0.0 8.1e-23 80.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Dyp_perox PF04261.7 KPI40688.1 - 1.4e-91 306.4 0.0 1.6e-91 306.2 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family EIF_2_alpha PF07541.7 KPI40689.1 - 1e-36 125.0 0.0 2.2e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KPI40689.1 - 7e-13 48.4 0.6 1.6e-12 47.3 0.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Alpha-amylase PF00128.19 KPI40690.1 - 2.8e-29 102.5 0.1 1.4e-19 70.6 0.1 2.1 2 0 0 2 2 2 2 Alpha amylase, catalytic domain DUF1939 PF09154.5 KPI40690.1 - 1e-06 28.4 0.0 4.3e-06 26.5 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Glyco_hydro_70 PF02324.11 KPI40690.1 - 0.014 13.2 0.9 0.095 10.4 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 p450 PF00067.17 KPI40691.1 - 7.3e-54 183.0 0.0 9.5e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 2C_adapt PF08793.5 KPI40691.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 2-cysteine adaptor domain TPR_11 PF13414.1 KPI40692.1 - 1.8e-12 46.6 9.0 5.2e-07 29.2 0.3 5.6 4 1 1 5 5 5 3 TPR repeat TPR_2 PF07719.12 KPI40692.1 - 4e-08 32.5 8.1 0.051 13.5 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KPI40692.1 - 4.8e-08 32.2 0.1 0.089 12.4 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KPI40692.1 - 0.00011 22.7 15.0 0.019 15.6 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KPI40692.1 - 0.0013 18.6 12.7 0.15 12.0 0.6 4.7 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KPI40692.1 - 0.0023 17.5 0.2 1.3 8.9 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.4 KPI40692.1 - 0.016 14.6 0.1 0.32 10.3 0.0 2.3 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_17 PF13431.1 KPI40692.1 - 0.017 15.3 0.8 0.5 10.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KPI40692.1 - 0.026 14.3 3.0 8.5 6.4 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KPI40692.1 - 0.036 13.9 0.2 0.036 13.9 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KPI40692.1 - 1.8 9.4 24.4 3.2 8.6 0.2 7.0 5 2 2 7 7 7 0 Tetratricopeptide repeat Ank_2 PF12796.2 KPI40693.1 - 3.8e-32 110.4 1.3 4.7e-16 58.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KPI40693.1 - 9.5e-31 104.0 7.0 1.1e-09 37.6 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KPI40693.1 - 6.4e-26 90.2 1.0 8.8e-10 38.8 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KPI40693.1 - 2e-23 81.8 2.0 5.2e-09 36.0 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI40693.1 - 6.8e-23 78.4 0.6 4.1e-06 26.5 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat bZIP_1 PF00170.16 KPI40693.1 - 0.43 10.5 4.4 0.72 9.8 3.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor SnoaL_4 PF13577.1 KPI40694.1 - 2e-19 69.7 0.0 2.4e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain tRNA-synt_2d PF01409.15 KPI40695.1 - 5.1e-51 173.2 0.3 3.6e-28 98.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KPI40695.1 - 1.1e-26 92.8 0.0 2.6e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 KPI40695.1 - 0.052 12.3 0.2 1.4 7.6 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) DUF2034 PF10356.4 KPI40696.1 - 4.1e-18 65.2 0.1 3.5e-13 49.1 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 KPI40696.1 - 3e-05 23.7 0.0 0.00012 21.8 0.0 1.9 2 0 0 2 2 2 1 Restriction endonuclease FAD_binding_3 PF01494.14 KPI40697.1 - 5.3e-93 311.9 0.9 6.5e-93 311.6 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI40697.1 - 6.9e-07 28.4 0.8 0.022 13.6 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI40697.1 - 1.8e-06 27.9 0.0 1.1e-05 25.3 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI40697.1 - 1.3e-05 24.2 1.0 0.0024 16.8 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain Mqo PF06039.10 KPI40697.1 - 0.002 16.4 0.1 0.36 8.9 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.12 KPI40697.1 - 0.0029 16.7 0.4 0.0059 15.7 0.1 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 KPI40697.1 - 0.004 17.1 0.1 0.015 15.3 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 KPI40697.1 - 0.013 15.3 0.6 0.031 14.1 0.4 1.6 1 0 0 1 1 1 0 ThiF family GIDA PF01134.17 KPI40697.1 - 0.022 13.6 0.2 0.059 12.2 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 KPI40697.1 - 0.053 11.9 0.4 3.3 6.0 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 KPI40697.1 - 0.054 12.4 0.4 0.2 10.5 0.3 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 KPI40697.1 - 0.14 11.8 0.3 0.32 10.6 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 KPI40697.1 - 0.14 12.2 1.5 1 9.3 1.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_18 PF00704.23 KPI40698.1 - 3.4e-55 187.8 0.5 8.6e-55 186.5 0.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Fungal_trans PF04082.13 KPI40699.1 - 1.6e-23 82.8 0.4 2.4e-23 82.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_5 PF12695.2 KPI40700.1 - 4.5e-15 55.6 0.1 7.5e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI40700.1 - 3.2e-14 53.3 1.1 4.2e-14 52.9 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KPI40700.1 - 7.6e-08 31.2 0.0 2.5e-07 29.5 0.0 1.7 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) DUF1100 PF06500.6 KPI40700.1 - 3.7e-07 29.0 0.0 5e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.13 KPI40700.1 - 6.5e-07 28.8 0.0 1.8e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KPI40700.1 - 8.3e-07 28.4 0.1 1.7e-06 27.4 0.1 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 KPI40700.1 - 2.6e-05 24.0 0.0 4.3e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 KPI40700.1 - 0.00024 20.8 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Asp PF00026.18 KPI40701.1 - 5.5e-08 32.4 0.0 0.00022 20.6 0.0 3.7 3 1 0 3 3 3 2 Eukaryotic aspartyl protease Telomere_Sde2 PF13019.1 KPI40703.1 - 4.5e-46 156.4 1.0 1.2e-45 155.1 0.7 1.7 1 1 0 1 1 1 1 Telomere stability and silencing CFEM PF05730.6 KPI40704.1 - 1.2e-11 44.2 18.9 2.1e-11 43.4 13.1 1.4 1 0 0 1 1 1 1 CFEM domain TMEM154 PF15102.1 KPI40704.1 - 0.23 11.1 0.8 0.5 10.0 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family PLDc PF00614.17 KPI40705.1 - 3.6e-16 58.3 1.5 7.2e-09 35.1 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KPI40705.1 - 2.1e-14 53.3 0.0 4e-06 26.6 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain Sec63 PF02889.11 KPI40706.1 - 7.1e-52 176.5 0.0 1.1e-51 175.9 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 KPI40706.1 - 9.4e-29 100.0 0.1 3.9e-28 98.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KPI40706.1 - 1.4e-10 41.3 0.0 2.7e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KPI40706.1 - 4.4e-09 36.0 0.0 1.5e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KPI40706.1 - 7.2e-05 22.9 0.1 0.00028 21.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KPI40706.1 - 0.00037 20.0 0.0 0.45 9.8 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain SNF2_N PF00176.18 KPI40706.1 - 0.0011 17.8 0.2 0.014 14.2 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_19 PF13245.1 KPI40706.1 - 0.0068 16.1 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KPI40706.1 - 0.0076 15.8 0.0 0.032 13.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 KPI40706.1 - 0.0087 15.3 0.0 0.028 13.7 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain HHH_5 PF14520.1 KPI40706.1 - 0.0092 16.1 0.0 0.029 14.5 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain Helicase_RecD PF05127.9 KPI40706.1 - 0.014 15.0 0.0 0.5 9.9 0.0 2.4 2 0 0 2 2 2 0 Helicase T2SE PF00437.15 KPI40706.1 - 0.016 14.1 0.0 0.034 13.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Cdd1 PF11731.3 KPI40706.1 - 0.078 12.9 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Pathogenicity locus APH PF01636.18 KPI40707.1 - 1.5e-38 132.8 0.0 2e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KPI40707.1 - 4.9e-06 25.8 0.0 7.6e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 KPI40707.1 - 0.0074 15.2 0.0 0.58 9.0 0.0 2.2 1 1 0 1 1 1 1 Fructosamine kinase RIO1 PF01163.17 KPI40707.1 - 0.062 12.6 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 KPI40707.1 - 0.095 11.7 0.0 0.3 10.1 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.6 KPI40707.1 - 0.12 11.0 0.0 0.26 9.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) p450 PF00067.17 KPI40708.1 - 4.8e-42 144.0 0.0 6e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 KPI40709.1 - 2.2e-07 29.8 4.2 3.1e-07 29.3 0.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Reprolysin_5 PF13688.1 KPI40710.1 - 2.6e-58 197.1 9.1 2.6e-58 197.1 6.3 2.1 2 1 0 2 2 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KPI40710.1 - 1.4e-47 161.9 1.7 3.1e-47 160.7 1.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KPI40710.1 - 3.2e-45 154.2 3.4 7.2e-45 153.1 2.3 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KPI40710.1 - 6.6e-19 68.6 0.8 6.6e-19 68.6 0.6 2.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 KPI40710.1 - 9.6e-17 60.9 30.6 9.6e-17 60.9 21.2 4.5 2 1 2 4 4 2 1 Disintegrin Amidohydro_4 PF13147.1 KPI40710.1 - 6.9e-07 29.5 0.5 0.044 13.8 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KPI40710.1 - 0.00013 21.7 0.0 0.00041 20.0 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KPI40710.1 - 0.00019 20.7 0.0 0.00036 19.8 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Pep_M12B_propep PF01562.14 KPI40710.1 - 0.00045 20.0 0.0 0.00089 19.0 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Amidohydro_1 PF01979.15 KPI40710.1 - 0.0018 18.0 0.0 0.013 15.1 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family NeuB PF03102.9 KPI40710.1 - 0.24 10.5 0.0 0.4 9.7 0.0 1.2 1 0 0 1 1 1 0 NeuB family Reprolysin PF01421.14 KPI40710.1 - 0.68 9.4 14.4 0.049 13.1 4.5 2.8 1 1 1 2 2 2 0 Reprolysin (M12B) family zinc metalloprotease Transp_cyt_pur PF02133.10 KPI40711.1 - 2.6e-74 250.3 37.4 6.9e-74 248.9 25.9 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SyrA PF11089.3 KPI40711.1 - 0.011 15.4 0.9 0.036 13.8 0.6 1.8 1 0 0 1 1 1 0 Exopolysaccharide production repressor PrgI PF12666.2 KPI40711.1 - 4.9 7.3 14.4 2.4 8.3 0.4 3.9 3 0 0 3 3 3 0 PrgI family protein TcpE PF12648.2 KPI40711.1 - 9.5 6.4 8.5 2.4 8.3 0.2 3.4 3 0 0 3 3 3 0 TcpE family Palm_thioest PF02089.10 KPI40712.1 - 2.9e-56 190.4 0.0 4e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.6 KPI40712.1 - 0.0003 19.9 0.0 0.0028 16.7 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.13 KPI40712.1 - 0.0006 19.1 0.0 0.0041 16.4 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_6 PF12697.2 KPI40712.1 - 0.0017 18.2 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Imm33 PF15580.1 KPI40712.1 - 0.033 13.6 0.1 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 33 F-box PF00646.28 KPI40714.1 - 1.3e-05 24.7 0.1 0.00043 19.8 0.0 2.8 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 KPI40714.1 - 2.5 7.9 8.3 1.6 8.5 1.1 3.2 3 1 0 3 3 3 0 Leucine rich repeat WD40 PF00400.27 KPI40716.1 - 6.7e-17 60.6 1.5 3.6e-05 23.4 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 KPI40716.1 - 3.2e-09 36.6 0.0 3.2e-09 36.6 0.0 2.8 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 KPI40716.1 - 0.058 13.1 0.9 0.21 11.2 0.6 1.9 1 1 0 1 1 1 0 Sec23-binding domain of Sec16 Prp18 PF02840.10 KPI40716.1 - 0.092 12.5 0.7 0.55 10.0 0.1 2.4 2 0 0 2 2 2 0 Prp18 domain MFS_1 PF07690.11 KPI40717.1 - 8.9e-19 67.4 48.4 2.4e-14 52.8 25.0 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KPI40717.1 - 2.9e-08 32.3 18.9 3.9e-08 31.9 13.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KPI40717.1 - 0.036 13.8 2.3 0.055 13.2 0.3 2.4 2 0 0 2 2 2 0 MFS_1 like family IMS PF00817.15 KPI40718.1 - 4e-35 120.8 0.0 7.8e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KPI40718.1 - 5e-12 45.8 0.2 1.1e-11 44.7 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KPI40718.1 - 0.0018 18.2 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 1 IMS family HHH motif Glyco_hydro_46 PF01374.13 KPI40718.1 - 0.1 12.1 0.0 9.3 5.7 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 46 HHH_8 PF14716.1 KPI40718.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain adh_short PF00106.20 KPI40719.1 - 1.4e-27 96.6 0.4 1.9e-27 96.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI40719.1 - 1.8e-26 93.3 0.1 2.3e-26 93.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI40719.1 - 2.5e-14 53.3 0.2 3.6e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 KPI40719.1 - 0.0023 17.4 1.4 0.26 10.8 0.3 2.3 1 1 1 2 2 2 2 Zinc-binding dehydrogenase DFP PF04127.10 KPI40719.1 - 0.0088 15.6 0.7 0.018 14.6 0.5 1.5 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein DUF1372 PF07116.6 KPI40719.1 - 0.022 14.7 0.4 0.041 13.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) 3HCDH_N PF02737.13 KPI40719.1 - 0.072 12.7 0.9 0.12 12.0 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PEARLI-4 PF05278.7 KPI40719.1 - 0.11 11.8 0.3 0.15 11.3 0.2 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) MFS_1 PF07690.11 KPI40720.1 - 1.1e-37 129.6 31.8 4.6e-37 127.5 16.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.23 KPI40721.1 - 1.8e-78 263.8 0.0 2.8e-78 263.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI40721.1 - 0.1 13.5 0.1 0.28 12.1 0.0 1.8 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.19 KPI40722.1 - 1.8e-82 277.3 29.2 2.2e-82 277.0 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI40722.1 - 1.7e-26 92.7 42.6 1.5e-17 63.3 14.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.13 KPI40722.1 - 7.3e-05 21.4 4.2 0.063 11.7 0.1 2.1 2 0 0 2 2 2 2 Reduced folate carrier DUF1228 PF06779.9 KPI40722.1 - 0.037 14.0 0.3 0.037 14.0 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) DUF1751 PF08551.5 KPI40723.1 - 3.4e-25 88.2 1.2 7.7e-25 87.1 0.9 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KPI40723.1 - 7.5e-06 26.0 5.0 1.3e-05 25.2 3.5 1.3 1 0 0 1 1 1 1 Rhomboid family RNase_PH PF01138.16 KPI40724.1 - 3.8e-15 56.3 0.0 6.2e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 GFA PF04828.9 KPI40725.1 - 6.1e-19 67.7 4.0 1.2e-12 47.5 0.1 3.4 4 0 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 KPI40725.1 - 0.26 11.1 11.7 2.2 8.1 0.2 3.8 4 0 0 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.1 KPI40725.1 - 0.27 10.4 6.7 0.86 8.8 0.0 3.4 3 1 0 3 3 3 0 zinc-ribbon domain Rubredoxin PF00301.15 KPI40725.1 - 7.3 6.5 9.3 1.4 8.8 0.2 3.3 3 0 0 3 3 3 0 Rubredoxin Aha1_N PF09229.6 KPI40726.1 - 2.6e-33 114.7 0.1 4.3e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KPI40726.1 - 6.9e-16 58.4 0.5 1.3e-15 57.6 0.4 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Glyco_hydro_68 PF02435.11 KPI40726.1 - 0.032 12.9 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 Levansucrase/Invertase Polyketide_cyc2 PF10604.4 KPI40726.1 - 0.039 14.1 6.7 0.03 14.5 2.6 2.2 2 1 1 3 3 3 0 Polyketide cyclase / dehydrase and lipid transport Glyco_tranf_2_3 PF13641.1 KPI40727.1 - 1e-31 110.5 0.0 2.2e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KPI40727.1 - 7.6e-16 58.3 0.0 7.6e-16 58.3 0.0 3.1 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KPI40727.1 - 1e-13 51.2 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KPI40727.1 - 8.9e-12 44.6 0.1 2.5e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF872 PF05915.7 KPI40727.1 - 0.04 13.7 1.4 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF2737 PF10930.3 KPI40727.1 - 0.25 10.9 0.1 0.5 10.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) IncA PF04156.9 KPI40727.1 - 0.32 10.5 2.7 0.54 9.8 1.9 1.3 1 0 0 1 1 1 0 IncA protein Cellulose_synt PF03552.9 KPI40727.1 - 0.85 7.8 7.9 9.1 4.4 0.0 3.5 2 1 2 4 4 4 0 Cellulose synthase Pribosyltran_N PF13793.1 KPI40728.1 - 5e-40 135.8 0.2 1.2e-39 134.6 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KPI40728.1 - 1.7e-34 119.1 1.1 4e-27 95.1 0.5 2.9 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KPI40728.1 - 3.5e-10 39.6 0.6 8.4e-10 38.4 0.4 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KPI40728.1 - 0.0095 15.1 0.1 0.016 14.4 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase SNAP PF14938.1 KPI40729.1 - 8.9e-113 376.1 9.0 1e-112 375.9 6.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KPI40729.1 - 5e-08 32.7 14.8 6.9e-05 22.7 1.7 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KPI40729.1 - 5.9e-05 22.5 11.6 0.1 12.4 0.2 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KPI40729.1 - 0.0087 16.7 12.4 0.41 11.3 1.2 3.6 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KPI40729.1 - 0.012 15.2 14.9 0.7 9.5 0.8 3.7 1 1 2 3 3 3 0 TPR repeat Foie-gras_1 PF11817.3 KPI40729.1 - 0.02 14.3 4.4 0.045 13.2 2.2 2.0 1 1 1 2 2 2 0 Foie gras liver health family 1 TPR_6 PF13174.1 KPI40729.1 - 0.036 14.5 13.5 17 6.1 0.2 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat PhageMin_Tail PF10145.4 KPI40729.1 - 0.26 10.9 5.4 0.19 11.3 0.1 2.4 2 1 1 3 3 3 0 Phage-related minor tail protein TPR_19 PF14559.1 KPI40729.1 - 0.26 11.6 12.5 0.28 11.5 0.0 4.4 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KPI40729.1 - 0.61 10.0 5.5 14 5.7 0.2 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat NSF PF02071.15 KPI40729.1 - 1.8 9.4 14.9 0.82 10.4 0.4 5.8 6 0 0 6 6 5 0 Aromatic-di-Alanine (AdAR) repeat TPR_10 PF13374.1 KPI40729.1 - 2.8 7.9 5.3 32 4.6 0.1 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Catalase PF00199.14 KPI40730.1 - 1.6e-185 616.3 0.9 1.9e-185 616.0 0.6 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KPI40730.1 - 4.7e-10 39.1 0.1 1.5e-09 37.5 0.1 2.0 1 1 0 1 1 1 1 Catalase-related immune-responsive Clr5 PF14420.1 KPI40731.1 - 3.5e-17 62.0 1.0 9.4e-17 60.6 0.7 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_14 PF13428.1 KPI40731.1 - 7.6e-05 23.0 2.0 0.046 14.3 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KPI40731.1 - 0.00039 20.1 0.1 0.0017 18.1 0.0 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 KPI40731.1 - 0.0004 19.9 0.0 0.0016 18.0 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 KPI40731.1 - 0.00074 19.3 1.9 0.00074 19.3 1.3 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KPI40731.1 - 0.0017 17.9 0.1 0.012 15.4 0.0 2.5 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 KPI40731.1 - 0.0071 16.9 3.2 0.0082 16.7 0.8 2.3 2 1 0 2 2 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KPI40731.1 - 0.01 15.4 0.0 0.031 13.8 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 KPI40731.1 - 0.038 13.6 0.0 0.13 11.9 0.0 1.9 1 1 0 1 1 1 0 TPR repeat RPN7 PF10602.4 KPI40731.1 - 0.04 13.3 0.3 0.16 11.3 0.1 2.1 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_21 PF09976.4 KPI40731.1 - 0.11 12.4 0.2 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 KPI40731.1 - 0.12 12.8 0.1 0.84 10.2 0.0 2.6 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_4 PF07721.9 KPI40731.1 - 1 10.0 8.8 2.9 8.5 0.3 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KPI40731.1 - 3.5 7.6 6.5 2.5 8.1 0.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat p450 PF00067.17 KPI40732.1 - 2.5e-38 131.8 0.0 3.1e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 S6PP PF05116.8 KPI40732.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Glyco_hydro_2_N PF02837.13 KPI40733.1 - 2.5e-24 85.7 0.1 5e-24 84.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KPI40733.1 - 2.2e-14 53.0 0.0 3.6e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KPI40733.1 - 1.3e-07 32.0 0.0 1e-06 29.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 MmgE_PrpD PF03972.9 KPI40734.1 - 6.7e-64 215.7 0.1 8.1e-64 215.4 0.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Cnl2_NKP2 PF09447.5 KPI40735.1 - 0.00087 18.9 0.2 0.0018 17.9 0.1 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein Menin PF05053.8 KPI40735.1 - 0.0029 15.8 10.3 0.0041 15.3 7.2 1.1 1 0 0 1 1 1 1 Menin TMF_TATA_bd PF12325.3 KPI40735.1 - 0.0061 16.2 1.4 0.0063 16.2 0.1 1.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Nop14 PF04147.7 KPI40735.1 - 0.027 12.4 11.9 0.031 12.2 8.3 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KPI40735.1 - 0.068 11.6 12.0 0.083 11.3 8.3 1.2 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 KPI40735.1 - 1.2 8.0 18.9 2 7.4 13.1 1.2 1 0 0 1 1 1 0 BUD22 DUF605 PF04652.11 KPI40735.1 - 3.2 7.0 18.1 5 6.4 12.6 1.2 1 0 0 1 1 1 0 Vta1 like ORC6 PF05460.8 KPI40735.1 - 9 5.2 16.0 85 2.0 11.1 2.0 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ctf8 PF09696.5 KPI40736.1 - 1e-32 112.4 0.0 1.2e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 Ctf8 DUF1751 PF08551.5 KPI40737.1 - 0.004 17.4 0.6 0.004 17.4 0.4 1.6 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Snf7 PF03357.16 KPI40738.1 - 9.7e-47 158.5 15.7 1.2e-46 158.2 10.9 1.0 1 0 0 1 1 1 1 Snf7 Zwint PF15556.1 KPI40738.1 - 0.012 14.8 7.5 0.016 14.4 5.2 1.3 1 0 0 1 1 1 0 ZW10 interactor Reo_sigmaC PF04582.7 KPI40738.1 - 0.017 14.2 2.4 0.09 11.9 0.5 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF2205 PF10224.4 KPI40738.1 - 0.026 14.1 2.5 0.78 9.3 0.5 2.8 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) HHH_2 PF12826.2 KPI40738.1 - 0.08 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif CDC37_N PF03234.9 KPI40738.1 - 0.1 12.8 9.1 0.14 12.5 6.3 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding NPV_P10 PF05531.7 KPI40738.1 - 0.12 12.6 6.5 1.5 9.1 1.1 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.1 KPI40738.1 - 0.19 11.1 11.7 0.62 9.4 7.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) OmpH PF03938.9 KPI40738.1 - 0.26 11.1 17.0 0.054 13.4 7.6 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF1569 PF07606.6 KPI40738.1 - 0.37 10.6 3.2 0.28 11.1 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1569) Atg14 PF10186.4 KPI40738.1 - 1 8.2 7.9 1.4 7.7 5.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mod_r PF07200.8 KPI40738.1 - 1.4 8.8 12.1 0.16 11.8 3.3 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4337 PF14235.1 KPI40738.1 - 2.5 7.9 9.3 0.37 10.6 3.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) IncA PF04156.9 KPI40738.1 - 3.1 7.3 7.1 1.2e+02 2.1 5.0 2.4 1 1 0 1 1 1 0 IncA protein MFS_1 PF07690.11 KPI40739.1 - 1.4e-17 63.4 33.7 1.4e-17 63.4 23.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily PIRT PF15099.1 KPI40739.1 - 2.1 7.5 4.0 4.4 6.5 2.8 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family adh_short PF00106.20 KPI40740.1 - 2.7e-20 72.9 1.5 2.7e-20 72.9 1.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI40740.1 - 7.7e-12 45.4 0.1 1.3e-11 44.7 0.0 1.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI40740.1 - 7e-08 32.3 0.8 1.4e-07 31.4 0.5 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI40740.1 - 0.00027 20.4 0.8 0.00066 19.1 0.5 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KPI40740.1 - 0.016 14.4 0.7 0.027 13.7 0.5 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 KPI40740.1 - 0.049 13.6 1.4 0.12 12.3 0.6 1.8 2 0 0 2 2 2 0 NADH(P)-binding PKD_channel PF08016.7 KPI40741.1 - 4.3e-06 25.4 5.5 0.0035 15.8 0.7 2.2 2 0 0 2 2 2 2 Polycystin cation channel Hom_end_hint PF05203.11 KPI40741.1 - 0.5 10.0 2.7 0.72 9.5 1.3 1.6 2 0 0 2 2 2 0 Hom_end-associated Hint Ion_trans PF00520.26 KPI40741.1 - 2.9 7.0 17.3 1.7 7.8 3.4 2.3 1 1 1 2 2 2 0 Ion transport protein Alpha-amylase PF00128.19 KPI40742.1 - 4.2e-18 65.8 1.3 3.1e-15 56.4 0.5 2.8 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glycos_transf_1 PF00534.15 KPI40742.1 - 1.8e-07 30.7 0.0 3.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KPI40742.1 - 2.1e-07 31.1 0.0 7.7e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Fungal_trans PF04082.13 KPI40745.1 - 8.4e-17 60.8 1.3 1.2e-16 60.3 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ENTH PF01417.15 KPI40746.1 - 8.1e-48 161.4 0.0 1.3e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KPI40746.1 - 0.00053 18.7 0.0 0.00088 18.0 0.0 1.3 1 0 0 1 1 1 1 ANTH domain UIM PF02809.15 KPI40746.1 - 0.0024 17.2 6.1 0.39 10.4 0.2 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif DUF1720 PF08226.6 KPI40746.1 - 0.0059 16.6 27.0 0.0059 16.6 18.7 5.2 1 1 3 4 4 4 1 Domain of unknown function (DUF1720) DUF4264 PF14084.1 KPI40746.1 - 0.013 14.8 0.1 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) PAT1 PF09770.4 KPI40746.1 - 4 5.5 54.5 6.5 4.8 37.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mito_carr PF00153.22 KPI40747.1 - 2.9e-56 187.1 0.0 1.3e-19 69.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.26 KPI40749.1 - 1.3e-17 63.2 0.1 2.9e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain LIM_bind PF01803.11 KPI40750.1 - 2.7e-39 134.7 1.2 2.7e-39 134.7 0.8 1.7 2 0 0 2 2 2 1 LIM-domain binding protein BTB PF00651.26 KPI40752.1 - 0.0002 21.3 0.1 0.00025 21.0 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain Sugar_tr PF00083.19 KPI40753.1 - 1.5e-91 307.2 30.2 2e-91 306.8 20.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI40753.1 - 8.3e-24 83.9 38.7 3e-21 75.5 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI40753.1 - 8.5e-06 24.4 12.0 0.00015 20.3 2.8 3.5 2 2 1 3 3 3 2 MFS/sugar transport protein IncA PF04156.9 KPI40753.1 - 0.004 16.7 1.8 0.0063 16.1 0.0 2.2 2 0 0 2 2 2 1 IncA protein SnoaL_4 PF13577.1 KPI40755.1 - 1.7e-16 60.2 0.4 2.4e-16 59.8 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 KPI40755.1 - 0.00034 20.9 0.3 0.00052 20.3 0.2 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF779 PF05610.6 KPI40755.1 - 0.025 14.5 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF779) COX6B PF02297.12 KPI40756.1 - 3.6e-19 68.5 6.5 4.5e-19 68.2 4.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 KPI40756.1 - 0.0021 17.4 0.6 0.0034 16.7 0.4 1.3 1 0 0 1 1 1 1 APOBEC-like C-terminal domain UPF0203 PF05254.7 KPI40756.1 - 3.4 7.5 6.0 3.7 7.4 1.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Ion_trans_2 PF07885.11 KPI40757.1 - 9.3e-26 89.3 29.4 1e-15 57.2 4.2 3.5 4 0 0 4 4 4 2 Ion channel CENP-L PF13092.1 KPI40758.1 - 2.6e-20 72.8 0.2 3.9e-20 72.2 0.1 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Beta-lactamase PF00144.19 KPI40759.1 - 1.8e-43 148.8 0.5 3.3e-43 147.9 0.4 1.4 1 1 0 1 1 1 1 Beta-lactamase Aminotran_1_2 PF00155.16 KPI40760.1 - 4.8e-50 170.5 0.0 1e-46 159.5 0.0 2.2 1 1 0 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KPI40760.1 - 0.00044 18.6 0.0 0.00062 18.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KPI40760.1 - 0.00099 17.9 0.0 0.0013 17.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KPI40760.1 - 0.013 14.6 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase BCS1_N PF08740.6 KPI40761.1 - 2.1e-17 63.3 0.6 3.9e-17 62.4 0.4 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KPI40761.1 - 3.4e-16 59.6 0.0 4.5e-08 33.3 0.0 2.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KPI40761.1 - 1.5e-05 25.7 0.0 0.00021 22.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KPI40761.1 - 0.0077 15.3 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KPI40761.1 - 0.025 14.5 0.4 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 KPI40761.1 - 0.026 13.9 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KPI40761.1 - 0.037 13.7 0.0 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KPI40761.1 - 0.067 13.3 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KPI40761.1 - 0.077 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KPI40761.1 - 0.086 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF899 PF05988.7 KPI40762.1 - 3.6e-48 163.8 0.0 4.5e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) TFIIIC_sub6 PF10419.4 KPI40763.1 - 0.017 14.5 0.1 0.17 11.3 0.0 2.6 3 0 0 3 3 3 0 TFIIIC subunit Semialdhyde_dhC PF02774.13 KPI40763.1 - 0.15 11.8 1.6 10 5.9 0.1 2.9 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Spore_YtfJ PF09579.5 KPI40763.1 - 0.95 9.3 12.8 3.6 7.5 1.7 3.0 3 1 0 3 3 3 0 Sporulation protein YtfJ (Spore_YtfJ) Grp1_Fun34_YaaH PF01184.14 KPI40764.1 - 1.4e-37 129.0 17.1 1.8e-37 128.7 11.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3784 PF12650.2 KPI40764.1 - 2.8 7.9 8.6 0.68 9.9 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) GCFC PF07842.7 KPI40765.1 - 1.8e-27 96.3 1.3 3.9e-27 95.3 0.9 1.6 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 KPI40765.1 - 8.6e-15 54.2 1.1 1.6e-14 53.4 0.8 1.5 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.3 KPI40765.1 - 0.0022 18.0 7.2 0.0037 17.3 3.7 2.2 1 1 1 2 2 2 2 Tuftelin interacting protein N terminal G-patch_2 PF12656.2 KPI40765.1 - 0.013 15.3 0.3 0.044 13.6 0.2 1.8 1 0 0 1 1 1 0 DExH-box splicing factor binding site SART-1 PF03343.8 KPI40766.1 - 1.5e-126 423.2 55.4 1.9e-126 422.9 38.4 1.0 1 0 0 1 1 1 1 SART-1 family GET2 PF08690.5 KPI40768.1 - 0.015 14.5 0.1 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 DUF919 PF06034.6 KPI40768.1 - 0.042 13.4 0.4 0.073 12.7 0.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Acetyltransf_1 PF00583.19 KPI40769.1 - 2.8e-07 30.4 0.0 4.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI40769.1 - 6.3e-07 29.4 0.0 9.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI40769.1 - 0.00016 21.7 0.0 0.012 15.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF1155 PF06633.6 KPI40769.1 - 0.15 11.3 0.1 0.71 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1155) Aldo_ket_red PF00248.16 KPI40770.1 - 2.1e-40 138.3 0.0 2.8e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Ribonuc_L-PSP PF01042.16 KPI40770.1 - 1.3e-05 24.9 0.0 0.0023 17.6 0.0 2.4 1 1 1 2 2 2 2 Endoribonuclease L-PSP RHH_1 PF01402.16 KPI40770.1 - 0.042 13.7 0.1 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Acetyltransf_1 PF00583.19 KPI40772.1 - 9.6e-07 28.7 0.1 2.4e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KPI40772.1 - 0.00029 20.9 0.1 0.001 19.2 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KPI40772.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KPI40772.1 - 0.039 13.7 0.5 2.2 8.1 0.1 2.7 2 1 0 3 3 3 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KPI40772.1 - 0.065 12.9 0.0 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein PGBA_N PF15436.1 KPI40772.1 - 0.093 11.9 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA N-terminal Amidase PF01425.16 KPI40773.1 - 1.2e-26 93.5 7.0 2e-25 89.5 3.3 2.4 3 0 0 3 3 3 2 Amidase Sugar_tr PF00083.19 KPI40774.1 - 1.9e-27 95.9 21.9 2.1e-27 95.8 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3087 PF11286.3 KPI40774.1 - 7 5.8 6.6 2.7 7.1 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Epimerase PF01370.16 KPI40776.1 - 1.1e-20 74.1 0.0 1.6e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KPI40776.1 - 3.2e-10 39.3 0.0 5.7e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KPI40776.1 - 4.7e-07 29.8 0.0 7.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KPI40776.1 - 2e-06 27.9 0.0 4.8e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KPI40776.1 - 4.2e-06 25.6 0.0 8.9e-06 24.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KPI40776.1 - 0.00013 20.9 0.0 0.00037 19.5 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein KR PF08659.5 KPI40776.1 - 0.0014 18.2 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Ebola_NP PF05505.7 KPI40777.1 - 2.4 6.1 5.4 3.7 5.4 3.7 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein Nop14 PF04147.7 KPI40777.1 - 6 4.6 27.8 8.4 4.1 19.2 1.1 1 0 0 1 1 1 0 Nop14-like family NAD_binding_8 PF13450.1 KPI40778.1 - 2e-06 27.6 0.2 4.3e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KPI40778.1 - 9.9e-06 24.8 1.7 2.7e-05 23.3 1.2 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KPI40778.1 - 1.4e-05 24.9 0.3 0.00014 21.6 0.2 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KPI40778.1 - 0.00086 19.2 0.1 0.0011 18.9 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI40778.1 - 0.0019 18.5 0.1 0.021 15.1 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI40778.1 - 0.0041 16.0 0.1 0.013 14.4 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI40778.1 - 0.0054 15.6 0.5 0.0081 15.0 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KPI40778.1 - 0.0079 14.6 0.1 0.013 14.0 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 KPI40778.1 - 0.018 14.0 0.1 0.03 13.2 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KPI40778.1 - 0.023 14.7 0.1 0.043 13.8 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI40778.1 - 0.024 13.5 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 KPI40778.1 - 0.039 13.0 0.0 4.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.12 KPI40778.1 - 0.092 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Utp12 PF04003.7 KPI40779.1 - 3e-17 62.5 0.0 4.8e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family F-box-like_2 PF13013.1 KPI40780.1 - 0.0057 16.3 0.2 0.017 14.8 0.2 1.8 1 1 0 1 1 1 1 F-box-like domain DUF2407_C PF13373.1 KPI40781.1 - 5.3e-38 130.0 0.0 7.2e-38 129.6 0.0 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 KPI40781.1 - 1.4e-25 89.3 0.0 2.1e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 KPI40781.1 - 0.0013 18.1 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family tRNA-synt_1c PF00749.16 KPI40782.1 - 6.3e-101 337.1 0.0 8.3e-101 336.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KPI40782.1 - 1.2e-31 109.7 0.8 2.8e-30 105.2 0.0 3.2 4 0 0 4 4 4 1 tRNA synthetases class I (E and Q), anti-codon binding domain Phasin PF05597.6 KPI40783.1 - 0.052 13.3 0.2 4.8 6.9 0.2 2.1 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MSA-2c PF12238.3 KPI40783.1 - 0.087 12.4 6.8 0.11 12.1 4.7 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c KfrA_N PF11740.3 KPI40783.1 - 0.2 12.0 8.5 0.29 11.5 4.1 2.0 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term DUF1518 PF07469.7 KPI40783.1 - 0.3 11.2 6.9 0.73 10.0 4.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1518) Herpes_UL17 PF04559.7 KPI40783.1 - 0.77 8.2 5.1 0.88 8.0 3.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL17 protein GrpE PF01025.14 KPI40784.1 - 8.5e-41 139.2 6.4 5.1e-40 136.7 4.5 1.9 1 1 0 1 1 1 1 GrpE PMC2NT PF08066.7 KPI40784.1 - 0.22 11.8 2.4 0.21 11.8 0.5 1.8 2 0 0 2 2 2 0 PMC2NT (NUC016) domain HHH PF00633.18 KPI40785.1 - 0.0015 18.1 0.0 0.0051 16.4 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif ATP-synt_ab PF00006.20 KPI40786.1 - 9.1e-61 205.0 0.0 1.2e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KPI40786.1 - 6.6e-16 58.7 0.2 1.1e-15 58.0 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KPI40786.1 - 2.5e-12 46.8 0.8 4.7e-12 45.9 0.6 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KPI40786.1 - 0.00059 19.6 0.5 0.0015 18.4 0.3 1.7 1 0 0 1 1 1 1 HAS barrel domain Sugar_tr PF00083.19 KPI40787.1 - 3.3e-17 62.2 5.9 3.6e-17 62.0 4.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI40787.1 - 0.0061 15.3 1.3 0.0072 15.0 0.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC_membrane PF00664.18 KPI40787.1 - 1.5 8.1 7.1 4.9 6.4 0.1 2.0 2 0 0 2 2 2 0 ABC transporter transmembrane region DUF1476 PF07345.6 KPI40788.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1476) TRI12 PF06609.8 KPI40790.1 - 3.6e-42 144.3 27.3 4.6e-42 144.0 18.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI40790.1 - 4.6e-12 45.3 16.8 4.6e-12 45.3 11.7 3.1 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI40790.1 - 3e-09 35.9 15.5 3e-09 35.9 10.7 4.1 1 1 2 4 4 4 1 Sugar (and other) transporter HRDC PF00570.18 KPI40790.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 HRDC domain FAD_binding_3 PF01494.14 KPI40791.1 - 3.3e-13 49.4 0.3 3.4e-12 46.1 0.2 2.2 1 1 0 1 1 1 1 FAD binding domain HECT PF00632.20 KPI40792.1 - 1.1e-92 310.6 0.0 2.3e-92 309.5 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 KPI40792.1 - 2.3e-63 214.2 0.0 2.3e-63 214.2 0.0 3.1 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 KPI40792.1 - 3.2e-39 135.1 2.8 4.1e-39 134.7 0.0 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 KPI40792.1 - 6.2e-22 77.5 9.2 6.2e-22 77.5 6.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) Ssu72 PF04722.8 KPI40792.1 - 0.18 11.1 0.0 0.51 9.6 0.0 1.7 1 0 0 1 1 1 0 Ssu72-like protein DUF3237 PF11578.3 KPI40793.1 - 9.1e-18 63.9 0.0 1.1e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-C2H2_4 PF13894.1 KPI40794.1 - 7.5e-05 22.7 14.1 0.22 11.9 1.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI40794.1 - 0.00035 20.7 13.2 0.11 12.9 0.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type DUF2968 PF11180.3 KPI40794.1 - 0.031 13.6 1.7 0.057 12.7 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Snapin_Pallidin PF14712.1 KPI40794.1 - 0.076 13.3 0.8 0.23 11.8 0.4 1.8 2 0 0 2 2 2 0 Snapin/Pallidin OmpA PF00691.15 KPI40795.1 - 0.058 13.8 1.1 0.18 12.2 0.5 2.0 2 0 0 2 2 2 0 OmpA family Pyr_redox_3 PF13738.1 KPI40796.1 - 6.6e-23 81.8 0.0 6.5e-22 78.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI40796.1 - 6.9e-18 64.1 2.0 3.8e-15 55.0 0.1 3.2 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KPI40796.1 - 7.3e-10 38.2 0.0 1.2e-06 27.7 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KPI40796.1 - 8.9e-10 38.4 0.0 2.5e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KPI40796.1 - 9.3e-05 22.2 0.7 0.047 13.4 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KPI40796.1 - 0.00016 21.6 0.0 0.0019 18.1 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI40796.1 - 0.0028 16.6 0.0 0.018 13.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KPI40796.1 - 0.025 13.6 0.0 0.24 10.4 0.0 2.3 3 0 0 3 3 3 0 Thi4 family Shikimate_DH PF01488.15 KPI40796.1 - 0.066 13.3 0.0 26 4.9 0.0 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KPI40796.1 - 0.11 12.9 1.8 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 KPI40796.1 - 0.24 10.9 0.0 4.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain NAD_binding_1 PF00175.16 KPI40797.1 - 2.9e-13 50.3 0.0 5.6e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KPI40797.1 - 5.2e-10 39.3 0.0 8.7e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 KPI40797.1 - 1.2e-07 32.0 0.0 3.3e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Globin NAD_binding_6 PF08030.7 KPI40797.1 - 1.4e-05 25.0 0.0 5.3e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.3 KPI40797.1 - 2.8e-05 23.8 0.0 5.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Protoglobin Molydop_binding PF01568.16 KPI40797.1 - 0.082 12.7 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Ceramidase PF05875.7 KPI40798.1 - 6.4e-97 323.8 2.7 7.3e-97 323.6 1.9 1.0 1 0 0 1 1 1 1 Ceramidase DUF2306 PF10067.4 KPI40798.1 - 0.15 12.2 4.3 2 8.5 0.1 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2306) TauE PF01925.14 KPI40798.1 - 0.33 10.3 4.0 2.4 7.5 2.7 2.1 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE 6PF2K PF01591.13 KPI40799.1 - 4.9e-62 208.9 1.6 2.1e-56 190.4 0.0 2.2 1 1 1 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KPI40799.1 - 1e-34 119.9 0.0 1.7e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KPI40799.1 - 0.00036 20.4 0.0 0.00066 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KPI40799.1 - 0.002 17.4 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ThylakoidFormat PF11264.3 KPI40799.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Thylakoid formation protein HAD_2 PF13419.1 KPI40801.1 - 8.6e-13 48.8 0.1 1.4e-08 35.1 0.0 2.9 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KPI40801.1 - 0.00075 19.1 0.0 0.002 17.8 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like DUF1048 PF06304.6 KPI40801.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) Peptidase_S10 PF00450.17 KPI40802.1 - 9e-82 275.4 0.0 1.2e-81 275.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase PCNA_C PF02747.10 KPI40803.1 - 3.4e-50 169.2 0.0 5.5e-50 168.5 0.0 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 KPI40803.1 - 2.4e-33 114.3 2.2 2.2e-31 108.0 1.5 2.3 1 1 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 KPI40803.1 - 3e-06 26.5 0.0 0.016 14.3 0.0 2.1 1 1 1 2 2 2 2 Rad9 Rad1 PF02144.11 KPI40803.1 - 8.3e-06 24.7 0.2 0.0096 14.7 0.0 2.3 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Sugar_tr PF00083.19 KPI40804.1 - 1.7e-60 204.9 25.3 3.1e-37 128.2 2.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI40804.1 - 1.5e-11 43.6 21.4 1.5e-11 43.6 14.8 3.1 1 1 2 3 3 3 1 Major Facilitator Superfamily MFS_1 PF07690.11 KPI40806.1 - 5.3e-40 137.2 24.1 5.3e-40 137.2 16.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI40806.1 - 7.8e-08 31.3 6.2 7.8e-08 31.3 4.3 2.6 3 1 1 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.8 KPI40806.1 - 0.00021 19.6 0.9 0.00037 18.8 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Anoctamin PF04547.7 KPI40806.1 - 0.0024 16.6 0.1 0.0038 15.9 0.0 1.3 1 0 0 1 1 1 1 Calcium-activated chloride channel FPN1 PF06963.7 KPI40806.1 - 0.0043 15.5 0.6 0.0062 14.9 0.0 1.5 2 0 0 2 2 2 1 Ferroportin1 (FPN1) CTNNB1_binding PF08347.6 KPI40806.1 - 0.49 10.6 1.1 0.79 9.9 0.8 1.2 1 0 0 1 1 1 0 N-terminal CTNNB1 binding DBINO PF13892.1 KPI40807.1 - 0.01 15.8 16.6 0.014 15.4 11.5 1.2 1 0 0 1 1 1 0 DNA-binding domain DDHD PF02862.12 KPI40807.1 - 0.21 11.3 1.3 0.24 11.1 0.9 1.1 1 0 0 1 1 1 0 DDHD domain DUF1682 PF07946.9 KPI40807.1 - 0.26 10.1 14.5 0.32 9.8 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Peptidase_S49_N PF08496.5 KPI40807.1 - 1.9 8.2 7.6 2.6 7.7 5.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PBP_sp32 PF07222.7 KPI40807.1 - 5 6.2 7.9 6.5 5.8 5.5 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 NARP1 PF12569.3 KPI40807.1 - 8 5.0 10.5 9.7 4.8 7.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Acid_PPase PF12689.2 KPI40808.1 - 7.2e-47 159.1 0.0 2.9e-44 150.6 0.0 2.2 1 1 0 1 1 1 1 Acid Phosphatase ATE_C PF04377.10 KPI40809.1 - 4.3e-41 139.9 0.8 6.6e-41 139.3 0.6 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus Fungal_trans_2 PF11951.3 KPI40810.1 - 0.051 12.1 2.5 0.06 11.9 0.4 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain Nro1 PF12753.2 KPI40810.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 GRAB PF10375.4 KPI40811.1 - 0.0074 15.9 19.7 31 4.5 0.1 6.1 6 0 0 6 6 6 0 GRIP-related Arf-binding domain DUF1493 PF07377.7 KPI40811.1 - 0.36 10.9 2.8 9.1 6.4 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) PepSY_2 PF13670.1 KPI40811.1 - 2.4 8.1 5.0 1.4 8.8 1.7 2.1 2 1 0 2 2 2 0 Peptidase propeptide and YPEB domain DNA_Packaging PF11053.3 KPI40811.1 - 6.1 6.4 11.0 9.9 5.7 1.4 2.6 1 1 2 3 3 3 0 Terminase DNA packaging enzyme OprF PF05736.6 KPI40811.1 - 7.1 6.1 7.6 42 3.6 0.4 3.2 2 1 2 4 4 4 0 OprF membrane domain Mt_ATP-synt_D PF05873.7 KPI40812.1 - 8.9e-15 54.6 0.4 1.2e-14 54.3 0.3 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) TPR_MLP1_2 PF07926.7 KPI40812.1 - 0.0027 17.4 1.0 0.0062 16.2 0.7 1.6 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.5 KPI40812.1 - 0.22 11.6 1.1 1.2 9.3 0.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.2 KPI40812.1 - 1.7 8.5 5.3 15 5.4 1.0 2.4 1 1 0 2 2 2 0 Tropomyosin like GATA PF00320.22 KPI40813.1 - 1.9e-15 55.9 3.6 3.2e-15 55.1 2.0 1.8 2 0 0 2 2 2 1 GATA zinc finger Macoilin PF09726.4 KPI40813.1 - 0.00067 18.0 1.3 0.00075 17.9 0.9 1.1 1 0 0 1 1 1 1 Transmembrane protein CENP-F_leu_zip PF10473.4 KPI40813.1 - 0.0048 16.7 3.8 0.0075 16.1 2.6 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TF_Zn_Ribbon PF08271.7 KPI40813.1 - 0.012 14.9 0.3 0.021 14.1 0.2 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Cep57_CLD_2 PF14197.1 KPI40813.1 - 0.025 14.4 9.8 0.041 13.8 6.8 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF904 PF06005.7 KPI40813.1 - 0.045 14.0 1.8 0.045 14.0 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF3328 PF11807.3 KPI40814.1 - 9.7e-34 116.9 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) p450 PF00067.17 KPI40815.1 - 1.2e-40 139.5 0.0 7.3e-34 117.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Galactosyl_T PF01762.16 KPI40816.1 - 0.034 13.7 0.1 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Galactosyltransferase Carn_acyltransf PF00755.15 KPI40817.1 - 4.6e-173 576.4 0.2 5.3e-173 576.2 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AA_permease_2 PF13520.1 KPI40818.1 - 1.3e-51 175.5 54.3 1.6e-51 175.2 37.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI40818.1 - 2.7e-16 58.9 45.7 4.3e-16 58.3 31.7 1.2 1 0 0 1 1 1 1 Amino acid permease Carn_acyltransf PF00755.15 KPI40819.1 - 0.1 10.6 0.0 0.15 10.1 0.0 1.2 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase Sugar_tr PF00083.19 KPI40820.1 - 5.1e-44 150.5 3.3 5.5e-44 150.4 2.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI40820.1 - 9.8e-14 50.8 10.0 1.1e-13 50.6 6.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Ubie_methyltran PF01209.13 KPI40821.1 - 3.9e-11 42.5 0.0 5.8e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KPI40821.1 - 2.9e-10 40.4 0.0 5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI40821.1 - 9.7e-09 35.5 0.0 3.2e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI40821.1 - 1.2e-07 32.1 0.0 2.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI40821.1 - 3e-07 30.1 0.0 4.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI40821.1 - 1.6e-05 24.8 0.0 3.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI40821.1 - 0.0092 15.7 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI40821.1 - 0.015 15.8 0.0 0.033 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Hydrolase PF00702.21 KPI40823.1 - 8.9e-24 85.0 0.0 3.1e-23 83.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KPI40823.1 - 1.7e-19 70.7 0.0 3.5e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KPI40823.1 - 2e-17 63.0 0.0 8.9e-17 60.8 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KPI40823.1 - 2.7e-05 24.0 0.0 6.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KPI40823.1 - 0.0017 17.9 0.2 0.013 15.0 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase G0-G1_switch_2 PF15103.1 KPI40823.1 - 0.17 12.1 2.2 0.53 10.5 0.0 2.7 3 0 0 3 3 3 0 G0/G1 switch protein 2 Nop16 PF09420.5 KPI40824.1 - 8.2e-49 165.8 8.1 9.5e-49 165.6 5.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 WD40 PF00400.27 KPI40825.1 - 1.5e-09 37.3 0.1 0.00019 21.1 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat BSD PF03909.12 KPI40826.1 - 3.3e-23 81.1 2.0 3.6e-12 45.8 0.1 2.7 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 KPI40826.1 - 1.8e-17 62.7 0.0 4.3e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain CLASP_N PF12348.3 KPI40828.1 - 3.7e-05 23.1 0.1 0.00078 18.8 0.0 2.2 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.17 KPI40828.1 - 5.5e-05 22.9 0.5 2.6 8.3 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat HALZ PF02183.13 KPI40828.1 - 0.00017 21.1 4.7 2.1 8.1 0.0 3.6 2 1 1 3 3 3 2 Homeobox associated leucine zipper Adaptin_N PF01602.15 KPI40828.1 - 0.0084 14.4 1.6 0.064 11.5 1.1 2.1 1 1 0 1 1 1 1 Adaptin N terminal region Cnd3 PF12719.2 KPI40828.1 - 0.012 14.6 0.1 0.056 12.4 0.0 2.0 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain bZIP_1 PF00170.16 KPI40828.1 - 0.025 14.5 8.5 1.3 9.0 0.4 2.9 2 0 0 2 2 2 0 bZIP transcription factor Mod_r PF07200.8 KPI40828.1 - 0.084 12.7 4.4 0.26 11.1 3.1 1.8 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Cnd1 PF12717.2 KPI40828.1 - 0.11 12.3 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 TEX13 PF15186.1 KPI40828.1 - 0.14 11.7 6.1 0.76 9.3 2.0 2.5 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Spc7 PF08317.6 KPI40828.1 - 0.18 10.4 5.4 0.34 9.5 3.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.10 KPI40828.1 - 0.27 10.7 11.5 0.61 9.5 2.5 2.9 2 1 1 3 3 3 0 Septum formation initiator ADIP PF11559.3 KPI40828.1 - 0.4 10.5 9.8 0.94 9.3 6.8 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KPI40828.1 - 0.47 10.0 6.9 0.11 12.0 2.1 1.9 2 0 0 2 2 2 0 IncA protein GAS PF13851.1 KPI40828.1 - 0.99 8.5 11.9 0.067 12.3 4.5 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 KPI40828.1 - 1.8 8.4 10.9 1.3 8.9 4.4 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 KPI40828.1 - 5.6 6.7 15.6 0.064 12.9 4.5 2.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Aa_trans PF01490.13 KPI40829.1 - 1.8e-49 168.3 18.8 6.5e-27 94.0 5.2 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein MRVI1 PF05781.7 KPI40829.1 - 0.11 10.8 0.1 0.3 9.4 0.0 1.6 2 0 0 2 2 2 0 MRVI1 protein EF-hand_6 PF13405.1 KPI40830.1 - 1.2e-13 49.6 6.4 5.4e-05 22.7 0.5 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.27 KPI40830.1 - 4e-13 47.6 6.9 6.2e-05 22.0 0.3 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 KPI40830.1 - 1.9e-11 43.3 7.0 9.1e-05 22.0 0.6 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 KPI40830.1 - 3e-11 43.2 2.2 2.8e-05 24.1 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 KPI40830.1 - 3.8e-05 23.5 0.0 0.00019 21.3 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 KPI40830.1 - 0.00014 20.9 4.3 0.17 11.2 0.1 3.7 4 0 0 4 4 4 1 EF hand EF-hand_4 PF12763.2 KPI40830.1 - 0.0036 17.0 0.0 0.022 14.5 0.0 2.0 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Toprim_2 PF13155.1 KPI40830.1 - 0.015 15.6 0.0 2.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Toprim-like HTH_39 PF14090.1 KPI40830.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain EFhand_Ca_insen PF08726.5 KPI40830.1 - 0.15 12.0 0.5 0.54 10.2 0.0 2.2 3 0 0 3 3 3 0 Ca2+ insensitive EF hand DUF4106 PF13388.1 KPI40830.1 - 0.5 9.2 8.6 0.69 8.8 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Methyltransf_10 PF05971.7 KPI40832.1 - 1.4e-35 122.9 2.9 2e-22 79.6 0.1 3.8 2 2 0 2 2 2 2 Protein of unknown function (DUF890) Methyltransf_18 PF12847.2 KPI40832.1 - 1.2e-05 25.8 0.0 0.00011 22.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI40832.1 - 7.6e-05 22.7 0.0 0.00029 20.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KPI40832.1 - 0.012 14.9 0.0 0.6 9.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.8 KPI40832.1 - 0.017 14.2 0.1 0.027 13.6 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.1 KPI40832.1 - 0.038 14.8 0.0 0.11 13.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Cytochrom_C PF00034.16 KPI40834.1 - 3e-09 37.5 0.0 4.6e-09 36.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KPI40834.1 - 1.8e-08 34.3 1.1 1.5e-07 31.4 0.8 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KPI40834.1 - 0.0002 20.8 0.2 0.0014 18.1 0.1 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain Complex1_51K PF01512.12 KPI40835.1 - 3.2e-45 153.5 0.0 6.9e-45 152.4 0.0 1.6 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KPI40835.1 - 2.6e-19 68.0 1.1 5.2e-19 67.1 0.8 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KPI40835.1 - 2.6e-09 36.8 0.0 5.4e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 SLBB domain Fungal_trans PF04082.13 KPI40836.1 - 6.5e-18 64.5 0.1 1.1e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI40836.1 - 4.1e-07 29.8 6.4 7.2e-07 29.0 4.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KPI40837.1 - 1.8e-06 27.8 8.7 0.17 12.2 1.3 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI40837.1 - 0.019 15.2 0.2 0.019 15.2 0.2 3.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type DnaJ PF00226.26 KPI40839.1 - 3.7e-17 61.7 2.2 8.8e-17 60.6 1.5 1.7 1 0 0 1 1 1 1 DnaJ domain DUF3347 PF11827.3 KPI40839.1 - 0.084 12.8 0.4 0.15 12.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) E1-E2_ATPase PF00122.15 KPI40839.1 - 0.59 9.1 9.4 0.88 8.5 6.5 1.2 1 0 0 1 1 1 0 E1-E2 ATPase TRP PF06011.7 KPI40839.1 - 4.3 5.7 11.0 8.3 4.8 7.3 1.5 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel ADH_zinc_N PF00107.21 KPI40841.1 - 2.5e-23 82.0 0.0 4e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI40841.1 - 1.4e-21 76.2 0.2 3.1e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KPI40841.1 - 0.00028 21.7 0.0 0.0005 20.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KPI40841.1 - 0.013 16.0 0.1 0.049 14.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF2464 PF10240.4 KPI40841.1 - 0.027 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) ThiF PF00899.16 KPI40841.1 - 0.072 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 ThiF family Methyltransf_11 PF08241.7 KPI40841.1 - 0.13 12.7 0.0 0.5 10.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Prenyltransf PF01255.14 KPI40842.1 - 1.7e-69 233.3 0.2 2.3e-40 138.0 0.0 2.0 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase Fungal_trans PF04082.13 KPI40844.1 - 1.1e-12 47.3 0.1 3.3e-12 45.8 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain SNF2_N PF00176.18 KPI40845.1 - 3.7e-42 144.1 0.0 1.2e-40 139.2 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KPI40845.1 - 0.00018 21.3 0.0 0.00037 20.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI40845.1 - 0.064 13.0 0.0 5.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RRM_1 PF00076.17 KPI40846.1 - 4e-16 58.4 0.0 5.5e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI40846.1 - 5.4e-09 35.9 0.0 7.6e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI40846.1 - 9.6e-08 31.7 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KPI40846.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C2H2_4 PF13894.1 KPI40847.1 - 0.045 14.0 0.2 0.045 14.0 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger DUF1517 PF07466.6 KPI40848.1 - 0.013 14.4 1.2 0.022 13.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) EphA2_TM PF14575.1 KPI40848.1 - 0.021 15.1 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3481 PF11980.3 KPI40848.1 - 0.027 14.2 0.0 0.4 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) Syndecan PF01034.15 KPI40848.1 - 0.2 11.3 0.1 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Fe-ADH PF00465.14 KPI40849.1 - 4.4e-32 111.1 0.1 5.2e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KPI40849.1 - 0.00044 19.6 0.1 0.016 14.5 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase LigB PF02900.13 KPI40849.1 - 0.14 11.1 0.1 0.54 9.1 0.0 1.9 2 1 0 3 3 3 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase adh_short PF00106.20 KPI40850.1 - 1.1e-18 67.6 1.2 1.3e-17 64.1 0.9 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI40850.1 - 2.2e-12 47.2 0.1 6.5e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI40850.1 - 1.2e-09 38.1 0.4 2.3e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 KR domain Saccharop_dh PF03435.13 KPI40850.1 - 7.4e-06 25.1 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KPI40850.1 - 0.0059 15.5 0.0 0.0091 14.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KPI40850.1 - 0.011 15.8 0.1 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KPI40850.1 - 0.029 13.7 0.1 0.098 12.0 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family PLA2_B PF01735.13 KPI40851.1 - 0.1 10.7 1.2 0.15 10.2 0.8 1.1 1 0 0 1 1 1 0 Lysophospholipase catalytic domain adh_short_C2 PF13561.1 KPI40852.1 - 1.7e-24 86.9 0.8 2e-24 86.6 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI40852.1 - 3.1e-23 82.5 4.6 4.5e-23 81.9 3.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI40852.1 - 2.3e-08 33.9 4.0 6.4e-08 32.4 2.7 1.7 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KPI40852.1 - 0.014 15.0 0.1 0.033 13.8 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KPI40852.1 - 0.3 11.0 3.9 5.2 7.0 2.3 2.7 1 1 1 2 2 2 0 NADH(P)-binding BMC PF00936.14 KPI40852.1 - 4.7 6.9 9.5 0.12 12.0 0.4 2.6 3 0 0 3 3 3 0 BMC domain DUF3636 PF12331.3 KPI40853.1 - 6e-47 158.9 0.6 1.4e-46 157.7 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Atg14 PF10186.4 KPI40853.1 - 0.68 8.8 10.4 1.3 7.9 7.2 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FA_hydroxylase PF04116.8 KPI40854.1 - 4e-12 46.5 16.5 4e-12 46.5 11.4 2.6 1 1 2 3 3 3 1 Fatty acid hydroxylase superfamily Phos_pyr_kin PF08543.7 KPI40856.1 - 4.2e-09 35.9 0.0 7.8e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KPI40856.1 - 9.6e-08 31.4 0.0 5.1e-07 29.1 0.0 2.0 1 1 0 2 2 2 1 pfkB family carbohydrate kinase Diphthamide_syn PF01866.12 KPI40857.1 - 2.6e-104 348.7 0.0 3.5e-103 345.0 0.0 2.0 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Peptidase_M20 PF01546.23 KPI40858.1 - 1.1e-22 80.5 0.1 1.9e-22 79.6 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 KPI40858.1 - 2.8e-05 23.9 0.0 5.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.9 KPI40858.1 - 0.00093 18.9 0.1 0.0031 17.2 0.1 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain Bromodomain PF00439.20 KPI40859.1 - 2.5e-40 136.2 1.5 3.6e-19 68.4 0.1 2.5 2 0 0 2 2 2 2 Bromodomain AAA PF00004.24 KPI40860.1 - 1.6e-16 60.7 0.0 4.2e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KPI40860.1 - 2.8e-05 23.7 0.0 9e-05 22.1 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KPI40860.1 - 6.5e-05 23.0 0.1 0.00048 20.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KPI40860.1 - 0.00077 19.4 1.9 0.0047 16.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KPI40860.1 - 0.0013 19.5 0.0 0.0013 19.5 0.0 2.7 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KPI40860.1 - 0.0022 17.7 0.1 0.008 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF3328 PF11807.3 KPI40861.1 - 0.00025 20.7 2.2 0.0004 20.1 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.11 KPI40862.1 - 6.2e-17 61.3 34.2 1.9e-09 36.7 7.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KPI40862.1 - 0.01 13.9 0.0 4.7 5.1 0.0 3.2 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3290 PF11694.3 KPI40862.1 - 0.21 11.3 0.0 0.52 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF1162 PF06650.7 KPI40863.1 - 5.3e-90 301.3 0.0 1.2e-86 290.3 0.0 4.0 3 1 1 4 4 4 3 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KPI40863.1 - 4.1e-42 142.4 0.1 4.1e-42 142.4 0.1 2.4 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KPI40863.1 - 7.1e-07 29.3 2.4 1.3e-05 25.3 0.0 3.1 3 0 0 3 3 3 1 ATG C terminal domain Ald_Xan_dh_C2 PF02738.13 KPI40864.1 - 2.2e-195 650.1 1.5 3.2e-195 649.5 1.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KPI40864.1 - 4.1e-47 159.7 0.0 8.3e-47 158.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 KPI40864.1 - 3.6e-33 113.5 0.9 2.3e-32 110.9 0.0 2.9 4 0 0 4 4 4 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 KPI40864.1 - 9.9e-31 106.1 0.0 3.3e-30 104.4 0.0 2.0 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 KPI40864.1 - 6.3e-29 99.7 0.1 1.6e-28 98.4 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain p450 PF00067.17 KPI40864.1 - 2.9e-20 72.2 0.0 8.3e-19 67.4 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 Fer2 PF00111.22 KPI40864.1 - 8.8e-08 31.7 2.3 1.2e-07 31.3 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain MLANA PF14991.1 KPI40865.1 - 0.097 12.6 1.5 0.72 9.8 0.1 2.2 2 0 0 2 2 2 0 Protein melan-A DUF4386 PF14329.1 KPI40865.1 - 0.2 11.1 20.8 0.014 14.9 6.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4386) DUF1772 PF08592.6 KPI40865.1 - 0.76 9.5 10.7 0.98 9.1 2.0 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF1772) Sugar_tr PF00083.19 KPI40867.1 - 6.6e-89 298.5 28.9 7.5e-89 298.3 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI40867.1 - 2.4e-25 89.0 29.0 2.4e-25 89.0 20.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Cons_hypoth698 PF03601.9 KPI40867.1 - 0.0021 16.7 4.3 0.0047 15.6 3.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 698 Ribosomal_S6e PF01092.14 KPI40868.1 - 3.3e-53 178.6 0.5 7.3e-52 174.3 0.4 2.3 1 1 0 1 1 1 1 Ribosomal protein S6e MFS_1 PF07690.11 KPI40869.1 - 2.9e-34 118.3 39.1 2.9e-34 118.3 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zip PF02535.17 KPI40870.1 - 3.4e-59 200.4 4.4 9.5e-59 198.9 3.1 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter FtsX PF02687.16 KPI40870.1 - 0.35 10.6 8.5 0.22 11.2 1.5 2.7 2 1 0 2 2 2 0 FtsX-like permease family DUF456 PF04306.8 KPI40870.1 - 0.84 9.6 14.3 0.2 11.7 1.0 3.5 3 2 0 4 4 4 0 Protein of unknown function (DUF456) Chorismate_bind PF00425.13 KPI40871.1 - 1.4e-87 293.2 0.0 3e-87 292.2 0.0 1.6 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 KPI40871.1 - 5.8e-28 97.6 0.1 1.1e-25 90.2 0.0 3.0 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Ribosomal_L7Ae PF01248.21 KPI40871.1 - 6.9e-21 73.5 0.8 1.2e-20 72.8 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family NAD_binding_8 PF13450.1 KPI40872.1 - 8.2e-14 51.3 0.0 2.3e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KPI40872.1 - 1.4e-12 47.4 0.0 2.5e-10 40.0 0.0 3.0 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KPI40872.1 - 9.4e-08 31.9 0.0 0.0036 17.0 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KPI40872.1 - 2.4e-06 27.7 0.0 0.0064 16.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI40872.1 - 0.00037 19.5 1.7 0.0013 17.6 0.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI40872.1 - 0.001 18.9 0.0 0.26 11.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI40872.1 - 0.0032 17.8 0.1 0.028 14.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI40872.1 - 0.0059 15.1 0.1 0.2 10.0 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Toxin_62 PF15540.1 KPI40872.1 - 0.029 14.4 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 62 FMO-like PF00743.14 KPI40872.1 - 0.062 11.4 0.0 0.09 10.9 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Thi4 PF01946.12 KPI40872.1 - 0.12 11.4 0.1 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 KPI40872.1 - 0.17 10.9 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase MRG PF05712.8 KPI40873.1 - 3.6e-49 166.3 0.0 5.6e-49 165.6 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KPI40873.1 - 3.4e-08 33.0 0.4 8.1e-08 31.8 0.3 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF4470 PF14737.1 KPI40874.1 - 4.5e-19 68.0 0.2 7.7e-19 67.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 KPI40874.1 - 0.0003 20.6 7.6 0.0003 20.6 5.3 2.2 2 0 0 2 2 2 1 MYND finger DUF2804 PF10974.3 KPI40875.1 - 0.097 11.4 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) zf-RanBP PF00641.13 KPI40876.1 - 2.5e-18 64.8 11.1 1.2e-10 40.3 1.4 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KPI40876.1 - 4.5e-08 32.5 0.0 8.2e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 KPI40876.1 - 2.6e-07 31.0 0.0 4.3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 KPI40876.1 - 1.4e-05 24.9 0.0 3.2e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 KPI40876.1 - 2 8.2 8.8 1.3 8.9 1.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon p450 PF00067.17 KPI40877.1 - 3.5e-67 226.9 0.0 5.5e-67 226.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 FAA_hydrolase PF01557.13 KPI40877.1 - 7.6e-52 175.9 0.0 1.3e-51 175.1 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Phage_endo_I PF05367.6 KPI40877.1 - 0.043 13.2 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Phage endonuclease I Calcipressin PF04847.7 KPI40878.1 - 4.9e-38 130.5 0.8 7.6e-38 129.9 0.6 1.2 1 0 0 1 1 1 1 Calcipressin Cation_ATPase_N PF00690.21 KPI40879.1 - 0.024 14.1 0.0 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus HORMA PF02301.13 KPI40881.1 - 6.3e-29 100.9 0.0 1.3e-28 99.9 0.0 1.5 1 1 0 1 1 1 1 HORMA domain PHD PF00628.24 KPI40881.1 - 2.1e-05 24.0 9.2 4.5e-05 23.0 6.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KPI40881.1 - 0.076 12.3 4.4 0.17 11.2 3.0 1.7 1 0 0 1 1 1 0 PHD-finger zf-PHD-like PF15446.1 KPI40881.1 - 0.076 12.3 4.3 0.2 10.9 3.0 1.7 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain WD40 PF00400.27 KPI40883.1 - 4e-56 185.0 11.9 6.2e-09 35.3 0.0 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KPI40883.1 - 1.3e-11 44.0 0.2 2.9e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KPI40883.1 - 9e-11 41.1 0.1 1.9e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 KPI40883.1 - 0.01 15.3 1.0 6.3 6.1 0.0 2.9 2 1 1 3 3 3 0 PQQ-like domain CPSF_A PF03178.10 KPI40883.1 - 0.091 11.8 0.2 0.39 9.7 0.0 2.0 3 0 0 3 3 3 0 CPSF A subunit region ArsC PF03960.10 KPI40883.1 - 0.2 11.7 0.4 0.96 9.5 0.0 2.3 3 0 0 3 3 3 0 ArsC family PRANC PF09372.5 KPI40883.1 - 0.25 11.3 0.0 0.52 10.3 0.0 1.4 1 0 0 1 1 1 0 PRANC domain PA_decarbox PF05870.6 KPI40886.1 - 0.00057 19.3 3.9 0.00077 18.9 1.2 2.1 1 1 1 2 2 2 1 Phenolic acid decarboxylase (PAD) ATP-grasp_4 PF13535.1 KPI40887.1 - 0.0004 20.1 0.0 0.0006 19.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KPI40887.1 - 0.006 15.3 0.0 0.0077 15.0 0.0 1.1 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon HET PF06985.6 KPI40889.1 - 1.1e-05 25.6 0.0 3.8e-05 23.8 0.0 2.0 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.23 KPI40890.1 - 1.1e-72 244.6 0.0 2.2e-72 243.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KPI40890.1 - 2.5e-57 193.6 0.0 4.1e-57 192.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding_C PF13193.1 KPI40890.1 - 3.5e-10 40.6 0.0 2.4e-09 38.0 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 KPI40890.1 - 6.9e-09 35.4 0.0 2.8e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KPI40890.1 - 2.5e-08 34.0 0.0 5.5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KPI40890.1 - 0.00035 19.3 0.0 0.0022 16.7 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.15 KPI40890.1 - 0.0078 15.0 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Condensation domain TPP_enzyme_M PF00205.17 KPI40890.1 - 0.088 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Peptidase_M41 PF01434.13 KPI40891.1 - 1.2e-62 211.2 0.1 2.1e-62 210.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KPI40891.1 - 1.3e-42 145.1 0.0 3.2e-42 143.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KPI40891.1 - 7.1e-07 30.0 0.3 5.6e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KPI40891.1 - 3.7e-06 27.0 0.0 0.00059 19.9 0.0 2.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KPI40891.1 - 5e-06 26.2 0.0 1.6e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KPI40891.1 - 1e-05 25.5 0.0 3.2e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 KPI40891.1 - 0.00035 20.0 0.0 0.00086 18.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KPI40891.1 - 0.00078 18.2 0.0 0.0019 16.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 KPI40891.1 - 0.0011 18.3 0.4 0.037 13.4 0.1 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 KPI40891.1 - 0.0013 17.8 0.0 0.0025 16.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KPI40891.1 - 0.0013 18.5 0.0 0.0038 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KPI40891.1 - 0.0028 16.7 1.1 0.0071 15.4 0.2 1.9 1 1 1 2 2 2 1 Zeta toxin AAA_28 PF13521.1 KPI40891.1 - 0.0031 17.5 0.0 0.0075 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KPI40891.1 - 0.0033 17.3 0.0 0.008 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KPI40891.1 - 0.0034 16.5 0.3 0.0072 15.4 0.2 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KPI40891.1 - 0.0045 16.7 0.2 0.014 15.1 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 KPI40891.1 - 0.007 16.0 0.1 0.16 11.6 0.0 2.2 2 0 0 2 2 2 1 NACHT domain DUF815 PF05673.8 KPI40891.1 - 0.012 14.5 0.0 0.027 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 KPI40891.1 - 0.015 15.5 0.1 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Amidohydro_1 PF01979.15 KPI40893.1 - 3.3e-16 59.8 0.0 2.6e-15 56.9 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KPI40893.1 - 3.8e-11 42.6 0.7 4.5e-10 39.1 0.1 2.9 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 KPI40893.1 - 4.7e-07 30.1 0.6 0.011 15.7 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KPI40893.1 - 5e-06 25.9 0.0 0.0019 17.4 0.0 3.1 3 0 0 3 3 3 2 Amidohydrolase family MFS_1 PF07690.11 KPI40894.1 - 2.3e-24 85.7 50.3 5.6e-24 84.5 35.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily SPC25 PF06703.6 KPI40894.1 - 0.15 11.6 0.3 0.31 10.6 0.2 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF2763 PF10961.3 KPI40895.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2763) Glycoprotein_B PF00606.13 KPI40895.1 - 0.25 9.3 3.1 0.31 8.9 2.1 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B HAP PF03866.8 KPI40895.1 - 4.4 7.0 5.9 4.6 7.0 4.1 1.3 1 1 0 1 1 1 0 Hydrophobic abundant protein (HAP) F-box PF00646.28 KPI40896.1 - 8.7e-05 22.0 1.0 0.00014 21.3 0.0 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KPI40896.1 - 0.0013 18.4 0.2 0.0073 16.0 0.0 2.4 2 0 0 2 2 2 1 F-box-like NUDIX PF00293.23 KPI40897.1 - 4.8e-17 61.8 0.3 5.5e-17 61.6 0.2 1.0 1 0 0 1 1 1 1 NUDIX domain adh_short PF00106.20 KPI40898.1 - 2.3e-08 34.1 0.2 0.0054 16.6 0.0 2.5 3 0 0 3 3 3 2 short chain dehydrogenase FBPase PF00316.15 KPI40899.1 - 1.6e-116 388.6 0.0 1.8e-116 388.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 KPI40899.1 - 0.044 13.0 0.0 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 Inositol monophosphatase family MFS_1 PF07690.11 KPI40900.1 - 2.1e-34 118.8 18.1 2.5e-18 65.9 5.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI40900.1 - 5.4e-05 21.9 18.2 0.0021 16.7 4.5 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.8 KPI40900.1 - 0.019 13.1 11.0 0.21 9.6 1.8 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector MFS_1_like PF12832.2 KPI40900.1 - 0.077 12.7 8.2 0.27 11.0 0.4 3.4 3 0 0 3 3 3 0 MFS_1 like family OATP PF03137.15 KPI40900.1 - 0.24 9.4 3.3 6.7 4.6 0.0 2.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Acyl-CoA_dh_1 PF00441.19 KPI40902.1 - 9.3e-34 116.7 0.3 1.2e-33 116.2 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KPI40902.1 - 1.4e-20 72.5 0.1 3.5e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KPI40902.1 - 2.1e-07 31.2 0.3 3.5e-07 30.5 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Nup96 PF12110.3 KPI40903.1 - 3.5e-48 164.1 0.0 5e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 KPI40903.1 - 1.2e-41 141.7 0.0 1.9e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 KPI40903.1 - 5.2e-33 113.6 225.7 2.9e-11 43.5 34.3 10.5 4 3 4 8 8 8 5 Nucleoporin FG repeat region Sec16_C PF12931.2 KPI40903.1 - 0.31 10.7 0.0 0.55 9.9 0.0 1.3 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 DASH_Dad3 PF08656.5 KPI40904.1 - 0.076 12.7 0.2 1.4 8.6 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad3 Activator-TraM PF11657.3 KPI40904.1 - 0.13 11.7 0.6 2.4 7.6 0.2 2.2 1 1 1 2 2 2 0 Transcriptional activator TraM SLAC1 PF03595.12 KPI40905.1 - 1.6e-55 188.0 44.9 1.9e-55 187.7 31.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Adeno_E3_14_5 PF04834.7 KPI40905.1 - 0.55 10.6 10.1 0.66 10.4 0.1 3.2 3 0 0 3 3 3 0 Early E3 14.5 kDa protein Bac_luciferase PF00296.15 KPI40906.1 - 1.6e-49 168.6 0.1 3.1e-47 161.1 0.1 2.1 1 1 0 1 1 1 1 Luciferase-like monooxygenase Fungal_trans_2 PF11951.3 KPI40907.1 - 8.8e-16 57.4 0.1 2.1e-11 43.0 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Hexapep PF00132.19 KPI40908.1 - 3.8e-15 54.6 9.5 8.5e-07 28.2 0.9 4.7 3 2 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KPI40908.1 - 1.9e-08 33.7 0.4 0.00067 19.1 0.1 3.1 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Nop14 PF04147.7 KPI40909.1 - 0.049 11.5 15.1 0.062 11.2 10.5 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KPI40909.1 - 0.83 8.0 15.0 0.97 7.8 10.4 1.0 1 0 0 1 1 1 0 Daxx Family Dicty_REP PF05086.7 KPI40909.1 - 1.9 6.1 8.5 2.4 5.8 5.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PPP4R2 PF09184.6 KPI40909.1 - 2.9 7.3 19.2 5.4 6.4 13.3 1.4 1 0 0 1 1 1 0 PPP4R2 eIF-3c_N PF05470.7 KPI40909.1 - 6.3 4.7 7.7 7.4 4.5 5.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2457 PF10446.4 KPI40909.1 - 9 4.9 18.2 12 4.5 12.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cep57_CLD_2 PF14197.1 KPI40910.1 - 0.016 15.0 3.3 0.037 13.9 0.3 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 HBS1_N PF08938.5 KPI40910.1 - 0.13 12.3 1.9 10 6.2 0.0 2.5 2 0 0 2 2 2 0 HBS1 N-terminus DUF3166 PF11365.3 KPI40910.1 - 0.17 12.3 2.9 1.5 9.3 0.3 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3166) ADH_zinc_N PF00107.21 KPI40911.1 - 3.4e-17 62.2 0.0 6.6e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI40911.1 - 7.1e-05 23.7 0.0 0.00014 22.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KPI40911.1 - 0.0041 17.1 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding AMP-binding PF00501.23 KPI40912.1 - 4.4e-80 269.1 0.1 6.3e-80 268.6 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI40912.1 - 2.8e-22 79.4 0.0 4.9e-21 75.4 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF2045 PF09741.4 KPI40912.1 - 0.15 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2045) Ank_2 PF12796.2 KPI40913.1 - 1.5e-15 57.3 0.0 2.4e-07 30.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KPI40913.1 - 9.4e-14 51.4 0.5 9.2e-09 35.5 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI40913.1 - 8.6e-13 47.1 0.4 0.00061 19.7 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KPI40913.1 - 8.4e-12 44.9 0.6 8e-06 25.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KPI40913.1 - 4.9e-10 38.7 0.5 0.0016 18.1 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat OmpH PF03938.9 KPI40913.1 - 0.0026 17.7 6.2 0.0026 17.7 4.3 2.4 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) KilA-N PF04383.8 KPI40913.1 - 0.0054 16.3 3.8 0.0078 15.8 0.3 2.6 2 1 0 2 2 2 1 KilA-N domain Oligomerisation PF02410.10 KPI40913.1 - 0.11 12.5 0.1 0.51 10.4 0.0 2.2 2 0 0 2 2 2 0 Oligomerisation domain DIRP PF06584.8 KPI40913.1 - 0.11 12.3 2.3 0.33 10.8 1.6 1.7 1 0 0 1 1 1 0 DIRP PilJ PF13675.1 KPI40913.1 - 0.16 12.2 8.2 0.29 11.4 2.6 3.0 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4337 PF14235.1 KPI40913.1 - 2.2 8.0 15.4 7.5 6.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) TPR_MLP1_2 PF07926.7 KPI40913.1 - 2.5 7.8 18.9 3.4 7.4 8.3 3.1 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 KPI40913.1 - 2.9 5.6 8.4 5.4 4.7 5.8 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 KPI40913.1 - 3.6 6.4 9.2 5.9 5.7 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) IncA PF04156.9 KPI40913.1 - 6.6 6.2 19.1 12 5.4 0.2 2.2 2 0 0 2 2 2 0 IncA protein HAD PF12710.2 KPI40914.1 - 3.4e-07 30.6 0.0 4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PduV-EutP PF10662.4 KPI40914.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Pyr_redox_3 PF13738.1 KPI40915.1 - 9.7e-29 100.8 0.0 3.5e-28 99.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI40915.1 - 3.1e-17 61.9 0.0 5.7e-15 54.5 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KPI40915.1 - 1.2e-13 50.7 1.0 2.5e-10 39.7 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KPI40915.1 - 1.4e-10 41.4 0.0 2.3e-07 30.9 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI40915.1 - 4.5e-07 29.1 0.0 3.3e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI40915.1 - 6.3e-07 29.3 0.0 1.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KPI40915.1 - 1.1e-06 28.4 0.6 0.00022 21.0 0.0 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KPI40915.1 - 0.00037 19.6 0.4 0.088 11.8 0.0 2.6 3 0 0 3 3 3 2 FAD binding domain Shikimate_DH PF01488.15 KPI40915.1 - 0.0019 18.2 0.3 0.14 12.2 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 KPI40915.1 - 0.03 13.4 0.1 0.062 12.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family SAPS PF04499.10 KPI40920.1 - 5e-83 279.3 2.3 6.7e-83 278.9 0.0 1.9 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein Mito_fiss_reg PF05308.6 KPI40920.1 - 6.1 6.1 28.8 0.99 8.7 0.3 3.2 2 1 1 3 3 3 0 Mitochondrial fission regulator DUF2863 PF11062.3 KPI40921.1 - 0.093 10.8 0.0 0.14 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) Glyco_transf_90 PF05686.7 KPI40922.1 - 1.8e-14 53.2 11.7 7.1e-14 51.3 5.2 2.4 2 1 0 2 2 2 2 Glycosyl transferase family 90 RabGAP-TBC PF00566.13 KPI40923.1 - 4.3e-46 157.0 0.1 7.5e-45 153.0 0.1 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TMPIT PF07851.8 KPI40923.1 - 2.6 7.0 10.2 5.4 5.9 7.1 1.5 1 0 0 1 1 1 0 TMPIT-like protein DUF972 PF06156.8 KPI40923.1 - 4.7 7.6 17.8 4.2 7.7 9.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Zn_clus PF00172.13 KPI40924.1 - 3.4e-09 36.4 10.2 7.8e-09 35.3 7.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med9 PF07544.8 KPI40925.1 - 0.00041 20.0 2.3 0.0013 18.4 0.7 2.5 2 1 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 BLOC1_2 PF10046.4 KPI40925.1 - 0.0046 17.0 1.3 0.43 10.7 0.0 2.4 1 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_N PF10481.4 KPI40925.1 - 0.012 15.0 4.9 0.73 9.1 0.1 2.2 2 0 0 2 2 2 0 Cenp-F N-terminal domain Bacillus_HBL PF05791.6 KPI40925.1 - 0.025 13.9 0.2 0.06 12.7 0.0 1.6 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF948 PF06103.6 KPI40925.1 - 0.053 13.3 0.2 0.15 11.9 0.0 1.8 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF948) PolyA_pol PF01743.15 KPI40925.1 - 0.12 12.5 3.5 0.85 9.8 2.3 2.3 1 1 0 1 1 1 0 Poly A polymerase head domain bZIP_1 PF00170.16 KPI40925.1 - 0.12 12.2 2.5 0.14 12.1 0.6 1.9 2 0 0 2 2 2 0 bZIP transcription factor Nup54 PF13874.1 KPI40925.1 - 0.13 11.9 11.2 14 5.2 0.0 3.0 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF1664 PF07889.7 KPI40925.1 - 0.14 11.9 2.5 1.7 8.4 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) APG6 PF04111.7 KPI40925.1 - 0.18 10.8 5.7 0.26 10.2 4.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Cluap1 PF10234.4 KPI40925.1 - 0.21 10.7 6.6 0.3 10.2 4.6 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Acetyltransf_11 PF13720.1 KPI40925.1 - 0.26 11.5 2.6 2.2 8.5 0.3 2.5 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 LXG PF04740.7 KPI40925.1 - 0.28 10.9 3.9 0.47 10.2 2.7 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily Mnd1 PF03962.10 KPI40925.1 - 0.36 10.4 4.4 0.53 9.9 3.1 1.3 1 0 0 1 1 1 0 Mnd1 family DUF4200 PF13863.1 KPI40925.1 - 0.59 10.0 8.5 0.93 9.4 5.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) PV-1 PF06637.6 KPI40925.1 - 0.66 8.4 5.9 0.92 7.9 4.1 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) ATG16 PF08614.6 KPI40925.1 - 0.67 9.7 9.5 1.6 8.5 3.6 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Tup_N PF08581.5 KPI40925.1 - 0.74 10.0 6.2 8.6 6.6 0.1 2.4 2 0 0 2 2 2 0 Tup N-terminal TMPIT PF07851.8 KPI40925.1 - 0.91 8.5 4.0 1.3 7.9 2.2 1.6 1 1 0 1 1 1 0 TMPIT-like protein ADIP PF11559.3 KPI40925.1 - 1.1 9.1 8.6 2.2 8.1 6.0 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding MCC-bdg_PDZ PF10506.4 KPI40925.1 - 1.2 9.0 4.4 0.41 10.4 0.5 2.1 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome bZIP_2 PF07716.10 KPI40925.1 - 1.5 8.7 6.9 0.34 10.7 1.3 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Cep57_MT_bd PF06657.8 KPI40925.1 - 2.5 8.0 6.6 0.46 10.4 0.1 2.8 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 IncA PF04156.9 KPI40925.1 - 8.2 5.9 11.1 14 5.2 7.7 1.4 1 0 0 1 1 1 0 IncA protein Inhibitor_I9 PF05922.11 KPI40926.1 - 2.7e-05 24.6 0.1 3.3e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 HET PF06985.6 KPI40928.1 - 1.8e-20 73.5 1.5 2.1e-18 66.7 1.1 2.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 KPI40928.1 - 6.2e-08 32.8 0.1 3.5e-06 27.2 0.0 2.7 1 1 2 3 3 3 1 Ankyrin repeats (3 copies) NACHT PF05729.7 KPI40928.1 - 4.7e-06 26.3 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.1 KPI40928.1 - 2.8e-05 24.4 0.1 0.0053 17.2 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) AAA_22 PF13401.1 KPI40928.1 - 0.00049 20.2 0.0 0.0016 18.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KPI40928.1 - 0.0011 19.0 0.4 0.0077 16.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Ank_3 PF13606.1 KPI40928.1 - 0.008 16.3 0.7 69 4.1 0.0 4.8 5 0 0 5 5 5 0 Ankyrin repeat Ank_5 PF13857.1 KPI40928.1 - 0.052 13.8 1.5 7.5 6.9 0.1 3.8 2 1 3 5 5 4 0 Ankyrin repeats (many copies) AAA_30 PF13604.1 KPI40928.1 - 0.072 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KPI40928.1 - 0.11 13.2 0.0 0.5 11.2 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KPI40928.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Ank PF00023.25 KPI40928.1 - 0.19 11.6 3.0 1e+02 2.9 0.0 4.5 5 0 0 5 5 5 0 Ankyrin repeat DnaJ PF00226.26 KPI40929.1 - 2e-21 75.4 0.1 2e-21 75.4 0.0 2.3 3 0 0 3 3 3 1 DnaJ domain Hom_end_hint PF05203.11 KPI40929.1 - 3.6 7.2 9.0 3.5 7.3 5.3 1.6 2 0 0 2 2 2 0 Hom_end-associated Hint Nuc_sug_transp PF04142.10 KPI40930.1 - 9.5e-75 250.8 9.3 9.5e-75 250.8 6.5 1.6 1 1 1 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 KPI40930.1 - 1.6e-07 31.5 3.1 1.6e-07 31.5 2.1 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KPI40930.1 - 7.6e-07 29.2 12.6 7.6e-07 29.2 8.7 3.5 2 2 1 3 3 3 1 EamA-like transporter family UAA PF08449.6 KPI40930.1 - 0.0002 20.4 17.6 0.0012 17.8 3.5 2.4 2 1 0 2 2 2 2 UAA transporter family TPT PF03151.11 KPI40930.1 - 0.00036 20.2 10.8 0.00036 20.2 7.5 2.8 2 1 1 3 3 3 1 Triose-phosphate Transporter family Herpes_LMP1 PF05297.6 KPI40930.1 - 0.14 11.0 5.7 0.14 11.0 2.5 2.1 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) UPF0546 PF10639.4 KPI40930.1 - 0.23 11.2 9.5 0.03 14.1 2.2 2.6 2 1 0 2 2 2 0 Uncharacterised protein family UPF0546 DUF486 PF04342.7 KPI40930.1 - 0.28 11.2 5.7 1.3 9.1 3.9 2.2 1 0 0 1 1 1 0 Protein of unknown function, DUF486 C2 PF00168.25 KPI40931.1 - 5.2e-21 74.2 0.0 2e-14 53.2 0.0 3.3 3 0 0 3 3 3 2 C2 domain Spermine_synth PF01564.12 KPI40932.1 - 1.4e-93 312.3 0.2 2.2e-93 311.7 0.1 1.3 2 0 0 2 2 2 1 Spermine/spermidine synthase DUF43 PF01861.11 KPI40932.1 - 0.00061 18.8 0.0 0.00092 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_18 PF12847.2 KPI40932.1 - 0.0013 19.2 0.0 0.0025 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI40932.1 - 0.0024 18.2 0.0 0.0043 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI40932.1 - 0.0059 17.0 0.1 0.04 14.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI40932.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KPI40932.1 - 0.055 12.8 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DSBA PF01323.15 KPI40934.1 - 1e-29 103.4 0.0 1.3e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 KPI40934.1 - 0.023 14.6 0.1 0.057 13.4 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin DIOX_N PF14226.1 KPI40935.1 - 5.7e-26 91.3 0.2 1.3e-25 90.1 0.1 1.7 1 1 1 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI40935.1 - 1.7e-21 76.3 0.0 4.9e-21 74.8 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DHBP_synthase PF00926.14 KPI40937.1 - 3.8e-75 251.3 0.1 8.3e-75 250.2 0.1 1.5 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Epimerase PF01370.16 KPI40938.1 - 0.0003 20.3 0.0 0.00067 19.1 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family SnoaL_2 PF12680.2 KPI40939.1 - 0.00045 20.5 0.1 0.00054 20.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF720 PF05302.6 KPI40940.1 - 2.2 8.0 15.1 4.2 7.1 10.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF720) PAT1 PF09770.4 KPI40940.1 - 4 5.5 32.0 4.3 5.4 22.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Meth_synt_2 PF01717.13 KPI40941.1 - 2.4e-12 46.4 0.0 0.0012 17.8 0.0 3.0 3 0 0 3 3 3 3 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KPI40941.1 - 5.4e-05 22.5 0.0 0.084 12.1 0.0 2.6 1 1 1 2 2 2 2 Cobalamin-independent synthase, N-terminal domain DUF2173 PF09941.4 KPI40941.1 - 0.068 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) MFS_1 PF07690.11 KPI40942.1 - 9.9e-35 119.8 36.4 1.5e-34 119.2 25.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily AMP-binding PF00501.23 KPI40943.1 - 4.4e-79 265.8 0.0 6e-79 265.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI40943.1 - 3e-13 50.5 0.1 4.1e-12 46.8 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Sld5 PF05916.6 KPI40944.1 - 1.2e-13 51.2 0.0 1.6e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Med19 PF10278.4 KPI40945.1 - 10 5.7 10.5 17 5.0 7.3 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Nitro_FeMo-Co PF02579.12 KPI40946.1 - 0.062 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor DSBA PF01323.15 KPI40947.1 - 9.9e-46 155.7 0.0 2.5e-21 76.1 0.0 3.0 2 1 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.1 KPI40947.1 - 0.0035 16.9 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin ThiC PF01964.13 KPI40947.1 - 0.087 11.3 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 ThiC family NAC PF01849.13 KPI40948.1 - 3.6e-24 84.0 0.0 4.1e-23 80.6 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 KPI40948.1 - 0.0032 17.2 0.1 0.0062 16.3 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RNA_pol_Rpo13 PF12136.3 KPI40948.1 - 0.14 11.8 2.9 0.34 10.6 2.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain CDC45 PF02724.9 KPI40948.1 - 0.27 9.2 9.4 0.031 12.3 2.5 1.8 2 0 0 2 2 2 0 CDC45-like protein Peptidase_C58 PF03543.9 KPI40948.1 - 0.28 10.6 3.4 0.42 10.0 2.4 1.2 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen SpoIIIAH PF12685.2 KPI40948.1 - 1.6 8.2 9.7 0.93 8.9 3.8 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein EBV-NA3 PF05009.7 KPI40948.1 - 2.7 7.1 7.9 7.4 5.7 0.5 2.3 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Rgp1 PF08737.5 KPI40950.1 - 1.4e-79 268.0 0.0 1.1e-78 265.1 0.0 2.2 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.24 KPI40950.1 - 0.00097 18.9 0.0 0.0052 16.6 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain SelB-wing_1 PF09105.5 KPI40950.1 - 0.03 13.9 0.1 0.088 12.4 0.1 1.7 1 0 0 1 1 1 0 Elongation factor SelB, winged helix DUF11 PF01345.13 KPI40950.1 - 0.03 14.3 0.4 0.14 12.2 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function DUF11 Arrestin_C PF02752.17 KPI40950.1 - 0.067 13.2 0.0 18 5.4 0.0 2.7 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Epimerase PF01370.16 KPI40951.1 - 6e-10 38.9 0.0 2e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI40951.1 - 1.2e-07 31.8 0.2 5.3e-07 29.8 0.2 2.1 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KPI40951.1 - 0.00058 19.1 0.0 0.0054 16.0 0.0 2.4 3 1 0 3 3 3 1 NmrA-like family NAD_binding_4 PF07993.7 KPI40951.1 - 0.0039 16.1 0.2 0.043 12.7 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KPI40951.1 - 0.043 12.5 0.0 0.081 11.6 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MutL_C PF08676.6 KPI40952.1 - 2.6e-22 78.9 0.0 1.7e-21 76.3 0.0 2.2 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KPI40952.1 - 2.8e-20 71.9 0.0 1.4e-19 69.7 0.0 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KPI40952.1 - 5.7e-12 45.4 0.0 1.4e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KPI40952.1 - 1.2e-11 44.2 0.0 2.9e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3236 PF11576.3 KPI40952.1 - 0.087 12.2 0.8 0.24 10.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) DUF3429 PF11911.3 KPI40953.1 - 8.4e-40 136.0 10.6 1.1e-39 135.6 7.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) CTP_transf_1 PF01148.15 KPI40954.1 - 4.7e-80 268.9 25.5 4.7e-80 268.9 17.7 3.5 3 1 0 3 3 3 1 Cytidylyltransferase family AA_permease_2 PF13520.1 KPI40954.1 - 7.8e-44 149.8 52.2 7.8e-44 149.8 36.2 3.2 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.16 KPI40954.1 - 2.2e-23 82.3 44.3 2.2e-23 82.3 30.7 2.5 2 1 0 2 2 2 1 Amino acid permease MFS_1 PF07690.11 KPI40956.1 - 2e-33 115.5 20.3 2.6e-33 115.2 13.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2142 PF09913.4 KPI40956.1 - 0.001 17.8 3.1 0.001 17.8 2.1 2.0 2 1 0 2 2 2 1 Predicted membrane protein (DUF2142) DUF3328 PF11807.3 KPI40957.1 - 2.6e-35 122.0 0.7 3.4e-35 121.7 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4231 PF14015.1 KPI40957.1 - 0.058 13.3 0.1 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Tyrosinase PF00264.15 KPI40958.1 - 1.5e-43 149.5 0.5 1.5e-43 149.5 0.3 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase 4HBT_3 PF13622.1 KPI40959.1 - 8.6e-26 91.2 3.1 1.1e-25 90.8 2.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KPI40959.1 - 1.8e-08 34.0 0.0 4.9e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA thioesterase Pectate_lyase PF03211.8 KPI40960.1 - 5e-31 107.7 1.4 6.6e-31 107.3 0.9 1.0 1 0 0 1 1 1 1 Pectate lyase AAA PF00004.24 KPI40961.1 - 3.1e-37 127.7 0.0 8.2e-37 126.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KPI40961.1 - 6.1e-06 26.1 0.3 0.0043 16.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KPI40961.1 - 8.5e-05 22.6 0.4 0.0065 16.6 0.0 3.6 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 KPI40961.1 - 9.2e-05 22.5 4.8 0.0031 17.5 0.0 3.9 4 1 1 5 5 4 1 AAA ATPase domain AAA_17 PF13207.1 KPI40961.1 - 0.00042 21.1 0.4 0.0016 19.2 0.0 2.2 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KPI40961.1 - 0.00051 19.1 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KPI40961.1 - 0.0025 17.7 0.0 0.0072 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KPI40961.1 - 0.0026 17.7 0.0 0.0067 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KPI40961.1 - 0.0035 16.7 0.0 0.0076 15.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KPI40961.1 - 0.004 16.8 0.2 0.014 15.1 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KPI40961.1 - 0.0069 16.1 0.0 0.022 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KPI40961.1 - 0.014 14.5 0.0 0.03 13.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KPI40961.1 - 0.021 15.0 0.0 0.096 12.8 0.0 2.2 2 0 0 2 2 1 0 RNA helicase AAA_25 PF13481.1 KPI40961.1 - 0.037 13.4 0.4 0.74 9.1 0.2 2.6 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 KPI40961.1 - 0.04 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KPI40961.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.8 KPI40961.1 - 0.044 12.4 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 KPI40961.1 - 0.071 12.6 0.2 0.15 11.5 0.2 1.5 1 0 0 1 1 1 0 AAA domain Glyco_hydro_31 PF01055.21 KPI40962.1 - 7.6e-116 387.5 0.2 9.7e-116 387.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KPI40962.1 - 1.8e-19 69.3 1.9 2.6e-19 68.8 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like MFS_1 PF07690.11 KPI40963.1 - 5.1e-22 78.0 19.7 5.1e-22 78.0 13.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 KPI40963.1 - 4.7e-12 45.7 3.8 4.7e-12 45.7 2.6 1.7 2 0 0 2 2 2 1 Nodulin-like MRP-L27 PF09809.4 KPI40964.1 - 6.4e-15 54.7 0.1 8.7e-15 54.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 MgsA_C PF12002.3 KPI40965.1 - 3.3e-54 183.0 0.0 5.5e-54 182.3 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 KPI40965.1 - 1.8e-15 57.3 0.0 4.4e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KPI40965.1 - 1.9e-11 43.4 0.0 5.3e-11 42.0 0.0 1.7 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KPI40965.1 - 1.1e-06 28.4 0.0 7.7e-06 25.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KPI40965.1 - 1.7e-06 27.3 0.0 0.041 13.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KPI40965.1 - 3.8e-06 26.4 0.0 3.5e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 KPI40965.1 - 7.2e-06 26.1 0.0 2.8e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KPI40965.1 - 1e-05 25.2 0.3 4.8e-05 23.0 0.0 2.3 2 0 0 2 2 1 1 Part of AAA domain AAA_16 PF13191.1 KPI40965.1 - 0.00019 21.4 1.9 0.0068 16.4 0.0 3.2 2 2 1 3 3 3 1 AAA ATPase domain zf-C2HC_2 PF13913.1 KPI40965.1 - 0.00062 19.3 0.3 0.0014 18.1 0.0 1.8 2 0 0 2 2 1 1 zinc-finger of a C2HC-type AAA_17 PF13207.1 KPI40965.1 - 0.00093 20.0 0.3 0.0027 18.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 KPI40965.1 - 0.001 18.9 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KPI40965.1 - 0.0015 18.1 0.0 0.0072 15.9 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 KPI40965.1 - 0.0016 18.4 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sgf11 PF08209.6 KPI40965.1 - 0.0017 17.6 0.1 0.0034 16.6 0.0 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) DUF815 PF05673.8 KPI40965.1 - 0.0032 16.4 0.0 0.0047 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 KPI40965.1 - 0.0068 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KPI40965.1 - 0.016 15.0 0.0 3.2 7.5 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Rad17 PF03215.10 KPI40965.1 - 0.023 13.3 0.0 4.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 KPI40965.1 - 0.025 14.7 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 RNA helicase TIP49 PF06068.8 KPI40965.1 - 0.026 13.2 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_33 PF13671.1 KPI40965.1 - 0.044 13.6 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KPI40965.1 - 0.063 12.8 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 KPI40965.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_30 PF13604.1 KPI40965.1 - 0.071 12.6 0.0 0.31 10.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KPI40965.1 - 0.089 12.7 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KPI40965.1 - 0.11 12.2 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 NTPase IstB_IS21 PF01695.12 KPI40965.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Parvo_NS1 PF01057.12 KPI40965.1 - 0.16 10.8 0.0 0.42 9.4 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_13 PF13166.1 KPI40965.1 - 0.17 10.3 0.1 0.25 9.7 0.1 1.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KPI40965.1 - 0.2 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Cutinase PF01083.17 KPI40966.1 - 1.3e-32 112.9 1.9 1.6e-32 112.6 1.3 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 KPI40966.1 - 0.00023 20.9 0.2 0.00029 20.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 KPI40966.1 - 0.0013 18.1 0.2 0.0021 17.5 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.2 KPI40966.1 - 0.0038 17.1 2.9 0.0058 16.5 1.3 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KPI40966.1 - 0.06 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.6 KPI40966.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Ferric_reduct PF01794.14 KPI40967.1 - 3.3e-22 78.8 8.1 8e-22 77.6 5.6 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KPI40967.1 - 7e-09 35.7 0.0 2.8e-05 24.0 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KPI40967.1 - 1.1e-08 34.8 0.0 6.2e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 KPI40967.1 - 1.1e-06 29.1 0.0 2.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain adh_short PF00106.20 KPI40968.1 - 1.4e-27 96.6 0.1 2.3e-27 95.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI40968.1 - 2.3e-13 50.4 0.0 3.1e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI40968.1 - 1.8e-11 44.0 0.1 2.5e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KPI40968.1 - 0.0033 17.1 0.2 0.0075 16.0 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KPI40968.1 - 0.0081 15.6 0.1 0.045 13.1 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KPI40968.1 - 0.01 14.7 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HisG_C PF08029.6 KPI40968.1 - 0.05 13.5 0.2 2.4 8.1 0.0 2.7 2 0 0 2 2 2 0 HisG, C-terminal domain His_Phos_2 PF00328.17 KPI40969.1 - 6.3e-16 58.6 0.0 9.8e-15 54.7 0.0 2.4 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) zf-C2H2_4 PF13894.1 KPI40969.1 - 5.1e-06 26.4 12.3 0.015 15.5 0.8 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI40969.1 - 5.5e-06 26.4 15.3 0.012 15.8 3.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KPI40969.1 - 2e-05 24.6 6.5 2e-05 24.6 4.5 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KPI40969.1 - 0.065 13.3 8.8 0.21 11.7 2.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.10 KPI40969.1 - 0.34 10.3 3.1 0.46 9.9 0.5 2.1 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HC_2 PF13913.1 KPI40969.1 - 2.3 7.9 6.8 3.1 7.5 1.0 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.2 KPI40969.1 - 2.6 8.3 9.0 3.6 7.9 1.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Apolipoprotein PF01442.13 KPI40970.1 - 1.2e-09 38.0 32.2 2.4e-05 23.9 6.5 3.2 2 1 1 3 3 3 3 Apolipoprotein A1/A4/E domain DUF1640 PF07798.6 KPI40970.1 - 0.00014 21.9 11.1 0.00014 21.9 7.7 3.7 2 1 2 4 4 4 1 Protein of unknown function (DUF1640) Baculo_PEP_C PF04513.7 KPI40970.1 - 0.0076 16.0 31.9 0.015 15.1 3.7 5.1 2 1 5 7 7 7 4 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.8 KPI40970.1 - 0.3 10.4 25.4 0.093 12.1 1.0 4.9 2 1 3 5 5 5 0 fzo-like conserved region DUF1664 PF07889.7 KPI40970.1 - 0.32 10.8 34.3 0.068 12.9 2.9 4.5 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) Prominin PF05478.6 KPI40970.1 - 1.1 6.7 24.4 0.36 8.3 0.8 3.1 1 1 0 2 2 2 0 Prominin ApoLp-III PF07464.6 KPI40970.1 - 3.6 7.6 40.6 8 6.4 4.5 4.4 2 2 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF2730 PF10805.3 KPI40970.1 - 4.7 7.0 11.5 1.3 8.7 0.0 4.5 3 1 3 6 6 6 0 Protein of unknown function (DUF2730) DnaJ PF00226.26 KPI40971.1 - 3.5e-10 39.4 0.1 8.2e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Sugar_tr PF00083.19 KPI40972.1 - 1e-59 202.3 10.2 1.2e-59 202.1 7.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI40972.1 - 3.6e-28 98.2 14.7 4.5e-28 97.9 10.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sclerostin PF05463.6 KPI40972.1 - 0.18 11.2 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Sclerostin (SOST) UPF0121 PF03661.8 KPI40973.1 - 2.8e-11 43.1 0.3 4.7e-11 42.3 0.2 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) zf-RAG1 PF10426.4 KPI40976.1 - 0.23 11.4 0.9 0.47 10.4 0.7 1.5 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain AAA_17 PF13207.1 KPI40977.1 - 0.00012 22.9 0.0 0.00023 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KPI40977.1 - 0.0028 17.9 0.0 0.0049 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain PRK PF00485.13 KPI40977.1 - 0.048 13.2 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 KPI40977.1 - 0.053 13.4 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.5 KPI40977.1 - 0.077 12.1 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 KPI40977.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter CPT PF07931.7 KPI40977.1 - 0.11 12.0 0.2 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 KPI40977.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KPI40977.1 - 0.14 12.0 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain Cupin_2 PF07883.6 KPI40978.1 - 6.5e-09 35.1 0.1 1.1e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KPI40978.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Med27 PF11571.3 KPI40979.1 - 9.3e-14 51.3 0.1 2.4e-13 50.0 0.1 1.7 1 0 0 1 1 1 1 Mediator complex subunit 27 TAF4 PF05236.9 KPI40980.1 - 2.1e-17 63.3 3.9 9.6e-17 61.1 2.7 2.1 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF4243 PF14027.1 KPI40980.1 - 0.8 9.0 5.1 1.2 8.4 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4243) ADH_N PF08240.7 KPI40981.1 - 4.6e-21 74.6 0.3 7.3e-21 73.9 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI40981.1 - 2e-20 72.6 0.1 3.2e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KPI40981.1 - 0.0029 16.7 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KPI40981.1 - 0.0078 15.7 0.7 0.014 14.9 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Asp PF00026.18 KPI40982.1 - 2.2e-104 349.1 0.0 2.6e-104 348.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KPI40982.1 - 6.5e-11 42.4 0.0 2e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KPI40982.1 - 1.7e-05 25.2 0.1 0.14 12.6 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 KPI40982.1 - 0.047 13.5 0.2 15 5.5 0.1 3.0 2 1 1 3 3 3 0 gag-polyprotein putative aspartyl protease PhyH PF05721.8 KPI40983.1 - 2.5e-26 93.0 0.0 4.9e-26 92.0 0.0 1.5 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) HAD_2 PF13419.1 KPI40985.1 - 2.4e-26 93.0 0.2 3.2e-26 92.5 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KPI40985.1 - 0.00014 22.3 0.0 0.00051 20.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KPI40985.1 - 0.028 14.1 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Sulfotransfer_3 PF13469.1 KPI40986.1 - 0.0013 19.6 0.2 0.0019 19.1 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family Shisa PF13908.1 KPI40987.1 - 0.007 16.5 3.6 0.012 15.7 2.5 1.4 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4064 PF13273.1 KPI40987.1 - 0.012 15.6 1.4 0.018 15.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Protocadherin PF08374.6 KPI40987.1 - 0.028 14.0 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Herpes_gE PF02480.11 KPI40987.1 - 0.06 11.6 0.1 0.11 10.6 0.1 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4381 PF14316.1 KPI40987.1 - 0.13 12.3 0.1 0.2 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3753 PF12575.3 KPI40987.1 - 0.38 10.5 2.9 0.5 10.1 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) P12 PF12669.2 KPI40987.1 - 3 8.1 4.6 4.5 7.5 3.2 1.2 1 0 0 1 1 1 0 Virus attachment protein p12 family p450 PF00067.17 KPI40988.1 - 1.2e-73 248.2 0.0 1.5e-73 247.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DEAD PF00270.24 KPI40989.1 - 6e-44 149.4 1.4 1.2e-43 148.4 0.9 1.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI40989.1 - 5.1e-27 93.5 0.1 1.5e-26 92.0 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI40989.1 - 0.00033 20.5 0.1 0.00085 19.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KPI40989.1 - 0.0015 18.1 0.1 0.003 17.1 0.1 1.4 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 KPI40989.1 - 0.0041 16.2 0.0 0.0078 15.3 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 KPI40989.1 - 0.016 15.3 0.4 0.061 13.4 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KPI40989.1 - 0.019 14.7 0.1 0.054 13.2 0.1 1.8 1 1 0 1 1 1 0 Part of AAA domain SNF2_N PF00176.18 KPI40989.1 - 0.047 12.4 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain CobA_CobO_BtuR PF02572.10 KPI40989.1 - 0.056 13.0 0.1 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP tRNA-synt_1b PF00579.20 KPI40989.1 - 0.1 11.6 0.0 0.35 9.9 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Helicase_RecD PF05127.9 KPI40989.1 - 0.13 11.9 0.1 0.27 10.8 0.1 1.6 1 1 0 1 1 1 0 Helicase Sugar_tr PF00083.19 KPI40990.1 - 1.2e-97 327.4 18.8 1.4e-97 327.1 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI40990.1 - 1.7e-21 76.3 24.7 2.1e-17 62.8 5.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KPI40990.1 - 0.00018 21.4 3.0 0.17 11.9 0.3 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) OATP PF03137.15 KPI40990.1 - 0.00047 18.3 0.9 0.00047 18.3 0.6 1.9 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF697 PF05128.7 KPI40990.1 - 0.77 9.2 3.6 1.4 8.3 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF697) Hist_deacetyl PF00850.14 KPI40991.1 - 1.3e-59 202.0 0.8 2e-59 201.4 0.6 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Pet127 PF08634.5 KPI40991.1 - 0.084 12.0 0.2 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial protein Pet127 EPL1 PF10513.4 KPI40991.1 - 1.8 8.7 8.7 9.5 6.4 6.1 2.2 1 0 0 1 1 1 0 Enhancer of polycomb-like TMEM171 PF15471.1 KPI40991.1 - 3.8 6.2 6.5 2.1 7.0 2.7 1.9 2 0 0 2 2 2 0 Transmembrane protein family 171 AMP-binding PF00501.23 KPI40993.1 - 3.1e-19 68.6 0.1 4.3e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Pkinase PF00069.20 KPI40994.1 - 5.4e-72 242.0 0.0 7.9e-71 238.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI40994.1 - 4.3e-44 150.5 0.0 7.5e-44 149.7 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI40994.1 - 1.1e-06 27.7 0.0 3.6e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KPI40994.1 - 0.00033 19.7 0.2 0.00059 18.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KPI40994.1 - 0.0055 16.0 0.7 0.082 12.2 0.0 2.3 2 1 0 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.4 KPI40994.1 - 0.0059 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 KPI40994.1 - 0.06 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribonuc_L-PSP PF01042.16 KPI40994.1 - 0.11 12.2 0.4 0.3 10.8 0.3 1.7 1 0 0 1 1 1 0 Endoribonuclease L-PSP E1-E2_ATPase PF00122.15 KPI40995.1 - 8.5e-58 195.0 0.1 2e-57 193.8 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KPI40995.1 - 5.4e-40 136.8 7.9 5.4e-40 136.8 5.5 2.4 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KPI40995.1 - 7.3e-27 95.1 0.0 2.1e-26 93.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KPI40995.1 - 2.5e-15 56.1 0.1 8e-15 54.5 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KPI40995.1 - 1.1e-14 55.0 0.1 2.5e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KPI40995.1 - 3.7e-08 32.6 0.0 2.4e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KPI40995.1 - 3.6e-07 30.0 0.4 1.8e-05 24.4 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 KPI40995.1 - 0.056 13.3 2.1 0.11 12.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) DUF3414 PF11894.3 KPI40995.1 - 0.075 9.9 0.0 0.12 9.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3414) NfeD PF01957.13 KPI40995.1 - 0.2 11.7 5.3 0.35 11.0 0.0 3.3 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding GFO_IDH_MocA PF01408.17 KPI40996.1 - 4.9e-21 75.4 0.1 7.5e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KPI40996.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Stathmin PF00836.14 KPI40997.1 - 0.096 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Stathmin family ASD2 PF08687.6 KPI40997.1 - 0.13 11.5 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Bap31 PF05529.7 KPI40998.1 - 5.9e-63 211.8 2.0 6.7e-63 211.6 1.4 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Prefoldin_2 PF01920.15 KPI40998.1 - 0.024 14.3 1.3 0.044 13.5 0.9 1.3 1 0 0 1 1 1 0 Prefoldin subunit DivIC PF04977.10 KPI40998.1 - 0.048 13.1 4.2 0.59 9.6 1.5 2.7 2 0 0 2 2 2 0 Septum formation initiator DUF4047 PF13256.1 KPI40998.1 - 0.11 12.4 0.2 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) bZIP_Maf PF03131.12 KPI40998.1 - 0.52 10.6 3.0 0.53 10.6 1.3 1.6 2 0 0 2 2 2 0 bZIP Maf transcription factor PQ-loop PF04193.9 KPI41000.1 - 8.3e-28 95.7 1.4 1.2e-19 69.5 0.1 2.7 2 0 0 2 2 2 2 PQ loop repeat Chromate_transp PF02417.10 KPI41000.1 - 0.15 11.6 2.9 0.5 9.9 0.0 2.5 1 1 2 3 3 3 0 Chromate transporter MFS_1 PF07690.11 KPI41001.1 - 5.8e-35 120.6 23.1 8.7e-35 120.0 16.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 KPI41001.1 - 0.0059 16.6 0.5 0.038 14.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) Snf7 PF03357.16 KPI41002.1 - 1.8e-34 118.6 22.0 1.8e-34 118.6 15.3 2.0 1 1 1 2 2 2 1 Snf7 Enoyl_reductase PF12241.3 KPI41002.1 - 0.026 13.5 1.1 0.035 13.0 0.8 1.2 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region HET PF06985.6 KPI41002.1 - 0.49 10.5 6.0 0.15 12.2 1.7 1.8 1 1 1 2 2 2 0 Heterokaryon incompatibility protein (HET) COMPASS-Shg1 PF05205.7 KPI41002.1 - 3.6 7.9 11.2 1.1 9.6 2.8 2.4 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 SPRY PF00622.23 KPI41003.1 - 5.2e-19 68.5 0.1 7.9e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 SPRY domain COX5B PF01215.14 KPI41005.1 - 2.7e-34 117.7 0.0 3.4e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb PhoD PF09423.5 KPI41006.1 - 4.7e-158 526.4 4.6 5.5e-158 526.2 3.2 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase TPP_enzyme_N PF02776.13 KPI41007.1 - 6.5e-56 188.4 1.4 1.3e-55 187.5 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KPI41007.1 - 1.5e-48 164.2 0.6 2.1e-46 157.2 0.0 3.1 3 1 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KPI41007.1 - 2.9e-38 130.7 1.4 8e-38 129.2 0.4 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain RICTOR_N PF14664.1 KPI41008.1 - 4.4e-121 403.9 1.3 8.7e-121 402.9 0.9 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KPI41008.1 - 4.3e-81 271.2 0.1 8.4e-80 267.0 0.1 2.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 KPI41008.1 - 1.9e-38 130.9 0.0 1.7e-37 127.8 0.0 2.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KPI41008.1 - 2e-21 75.7 6.2 3.7e-20 71.6 0.1 4.4 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 KPI41008.1 - 1.1e-07 31.4 2.7 2.6e-07 30.2 1.9 1.7 1 0 0 1 1 1 1 Hr1 repeat Proteasom_PSMB PF10508.4 KPI41008.1 - 0.0016 16.8 0.3 3.8 5.6 0.0 4.2 3 2 1 4 4 4 2 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.1 KPI41008.1 - 1.1 9.8 9.2 61 4.2 0.0 4.9 4 0 0 4 4 4 0 HEAT-like repeat Med19 PF10278.4 KPI41009.1 - 6.4e-05 22.6 10.2 7.1e-05 22.5 7.1 1.1 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 DUF1510 PF07423.6 KPI41009.1 - 0.00087 18.7 6.8 0.00087 18.7 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) U79_P34 PF03064.11 KPI41009.1 - 0.02 14.3 16.5 0.024 14.1 11.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FLO_LFY PF01698.11 KPI41009.1 - 0.046 12.5 9.3 0.048 12.5 6.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein CT47 PF15623.1 KPI41009.1 - 0.056 13.1 5.4 0.065 12.9 3.7 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 RNA_polI_A34 PF08208.6 KPI41009.1 - 0.08 12.6 20.9 0.1 12.2 14.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Vfa1 PF08432.5 KPI41009.1 - 0.098 12.6 12.0 0.13 12.3 8.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Tim54 PF11711.3 KPI41009.1 - 0.15 10.6 5.6 0.18 10.3 3.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 YqfQ PF14181.1 KPI41009.1 - 0.31 11.0 9.4 0.46 10.5 6.5 1.3 1 0 0 1 1 1 0 YqfQ-like protein Zip PF02535.17 KPI41009.1 - 0.34 9.8 1.3 0.33 9.9 0.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TATR PF03430.8 KPI41009.1 - 0.58 8.7 5.1 0.65 8.5 3.5 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF2796 PF10986.3 KPI41009.1 - 0.87 9.5 9.5 1.2 9.1 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) DDHD PF02862.12 KPI41009.1 - 1.1 8.9 4.6 1.3 8.8 3.2 1.1 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 KPI41009.1 - 1.2 9.0 5.9 1.3 8.8 4.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SspB PF04386.8 KPI41009.1 - 1.4 8.5 4.7 2.1 7.9 3.2 1.3 1 0 0 1 1 1 0 Stringent starvation protein B Ycf1 PF05758.7 KPI41009.1 - 1.4 6.5 5.7 1.7 6.2 4.0 1.0 1 0 0 1 1 1 0 Ycf1 SelP_N PF04592.9 KPI41009.1 - 1.7 7.9 8.0 2 7.7 5.6 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CDC45 PF02724.9 KPI41009.1 - 3.9 5.3 8.7 4.4 5.2 6.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Lon_C PF05362.8 KPI41010.1 - 1.9e-66 223.2 0.0 3.2e-66 222.5 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KPI41010.1 - 1.7e-35 122.5 0.1 4.3e-35 121.2 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KPI41010.1 - 1.2e-22 80.5 0.0 1.4e-21 77.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KPI41010.1 - 7.5e-07 28.9 0.0 1.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KPI41010.1 - 1.4e-06 28.3 0.0 4.3e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.1 KPI41010.1 - 7.2e-06 25.5 0.1 2.2e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 KPI41010.1 - 1.4e-05 25.2 0.1 0.00056 20.0 0.0 3.1 2 1 0 2 2 1 1 AAA domain AAA_PrkA PF08298.6 KPI41010.1 - 3.4e-05 22.7 0.0 7e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.1 KPI41010.1 - 9.9e-05 22.3 1.3 0.0013 18.7 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 KPI41010.1 - 0.0001 23.1 0.0 0.00045 21.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KPI41010.1 - 0.00022 20.3 0.0 0.0013 17.7 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KPI41010.1 - 0.0074 16.1 0.0 0.02 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 KPI41010.1 - 0.011 15.5 0.2 0.18 11.6 0.0 2.7 3 0 0 3 3 2 0 Shikimate kinase MobB PF03205.9 KPI41010.1 - 0.02 14.5 0.0 0.067 12.9 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KPI41010.1 - 0.026 14.7 0.0 0.18 12.0 0.0 2.5 3 0 0 3 3 2 0 RNA helicase AAA_18 PF13238.1 KPI41010.1 - 0.031 14.5 0.0 0.031 14.5 0.0 3.3 4 0 0 4 4 3 0 AAA domain IstB_IS21 PF01695.12 KPI41010.1 - 0.033 13.5 0.1 0.095 12.1 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein TIP49 PF06068.8 KPI41010.1 - 0.038 12.7 0.1 1 7.9 0.0 2.3 2 0 0 2 2 2 0 TIP49 C-terminus DUF258 PF03193.11 KPI41010.1 - 0.041 13.0 0.0 0.098 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KPI41010.1 - 0.078 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KPI41010.1 - 0.12 12.6 1.4 0.72 10.1 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_21 PF13304.1 KPI41010.1 - 0.13 12.1 2.4 2 8.2 0.0 3.3 3 1 1 4 4 4 0 AAA domain TauD PF02668.11 KPI41011.1 - 4e-50 170.9 0.0 4.6e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.19 KPI41012.1 - 2.5e-73 247.1 20.3 2.9e-73 246.9 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI41012.1 - 3.1e-15 55.7 29.4 2.4e-09 36.3 15.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Whi5 PF08528.6 KPI41013.1 - 7.4e-05 22.2 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Whi5 like SOG2 PF10428.4 KPI41013.1 - 3.7 6.1 7.7 5.1 5.6 5.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein GFO_IDH_MocA PF01408.17 KPI41014.1 - 7.6e-07 29.6 0.0 1.3e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KPI41014.1 - 0.00082 19.1 0.1 0.0034 17.1 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Pectate_lyase_3 PF12708.2 KPI41015.1 - 4.4e-77 259.1 10.8 2.7e-58 197.7 2.2 2.7 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KPI41015.1 - 6.8e-07 28.6 1.1 0.00037 19.9 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase CytochromB561_N PF09786.4 KPI41015.1 - 0.21 10.0 5.4 0.31 9.4 3.8 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Beta_helix PF13229.1 KPI41015.1 - 0.47 10.1 8.5 0.18 11.5 2.4 2.8 3 0 0 3 3 3 0 Right handed beta helix region Period_C PF12114.3 KPI41015.1 - 3.8 7.0 11.4 2.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Period protein 2/3C-terminal region BRO1 PF03097.13 KPI41016.1 - 2.4e-130 434.6 4.1 2.7e-130 434.4 2.9 1.0 1 0 0 1 1 1 1 BRO1-like domain MFS_1 PF07690.11 KPI41017.1 - 6.9e-34 117.0 25.9 1e-33 116.5 17.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1230 PF06799.6 KPI41017.1 - 0.056 13.3 1.8 0.41 10.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1230) ESSS PF10183.4 KPI41017.1 - 0.37 11.1 1.1 0.85 10.0 0.1 2.1 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) BTB PF00651.26 KPI41018.1 - 1.8e-09 37.5 0.0 3.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.3 KPI41018.1 - 0.0022 17.2 0.6 0.0038 16.4 0.4 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3342) COG5 PF10392.4 KPI41019.1 - 5.5e-26 91.0 3.7 1.4e-25 89.8 2.6 1.7 1 0 0 1 1 1 1 Golgi transport complex subunit 5 ECM11 PF15463.1 KPI41019.1 - 0.012 15.8 0.3 0.033 14.4 0.2 1.8 1 0 0 1 1 1 0 Extracellular mutant protein 11 GAS PF13851.1 KPI41019.1 - 0.18 10.9 4.4 0.03 13.5 0.5 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tannase PF07519.6 KPI41020.1 - 1.1e-52 179.3 0.1 1.8e-52 178.6 0.0 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase Sugar_tr PF00083.19 KPI41022.1 - 1.1e-75 254.9 23.1 1.4e-75 254.6 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI41022.1 - 3.4e-15 55.6 33.2 8.8e-15 54.2 17.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily EcsB PF05975.7 KPI41022.1 - 0.18 10.2 8.8 0.014 13.8 2.5 1.8 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB Ribosomal_S7 PF00177.16 KPI41023.1 - 4.8e-39 133.2 1.9 5.9e-39 132.9 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CYTH PF01928.16 KPI41024.1 - 1.5e-09 37.7 0.4 2.1e-09 37.3 0.3 1.2 1 0 0 1 1 1 1 CYTH domain BTB PF00651.26 KPI41025.1 - 5.9e-08 32.6 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF2962 PF11176.3 KPI41026.1 - 0.1 12.1 2.4 0.16 11.4 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2962) Pirin PF02678.11 KPI41027.1 - 0.0013 18.5 0.1 0.0045 16.8 0.1 1.8 1 0 0 1 1 1 1 Pirin ATG22 PF11700.3 KPI41028.1 - 4.7e-105 351.8 21.9 3.5e-102 342.3 15.2 2.0 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like SHOCT PF09851.4 KPI41028.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Short C-terminal domain NuA4 PF09340.5 KPI41030.1 - 1.8e-19 69.1 0.4 4e-19 68.0 0.0 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Gly-zipper_OmpA PF13436.1 KPI41030.1 - 1.8 8.2 9.5 2.6 7.7 6.6 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Ribosomal_60s PF00428.14 KPI41030.1 - 8.5 6.8 9.6 27 5.2 6.7 1.9 1 1 0 1 1 1 0 60s Acidic ribosomal protein Pkinase PF00069.20 KPI41031.1 - 1e-56 191.9 0.0 1.7e-56 191.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI41031.1 - 1.7e-20 73.1 0.0 6.8e-20 71.2 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase EHN PF06441.7 KPI41032.1 - 1.9e-33 114.7 0.0 3.4e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KPI41032.1 - 4e-09 36.6 1.1 2.2e-08 34.2 0.8 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI41032.1 - 3.8e-05 23.3 0.9 5.4e-05 22.8 0.2 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI41032.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family HA2 PF04408.18 KPI41033.1 - 5e-17 61.7 2.1 1.1e-16 60.7 0.1 2.4 2 1 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KPI41033.1 - 1.2e-13 50.7 0.0 3.2e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain adh_short PF00106.20 KPI41034.1 - 9.9e-19 67.8 0.1 1.8e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI41034.1 - 4.5e-10 39.7 0.2 1.2e-08 34.9 0.1 2.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI41034.1 - 8e-05 22.3 0.0 0.00025 20.7 0.0 1.8 2 0 0 2 2 2 1 KR domain DNA_pol_lambd_f PF10391.4 KPI41034.1 - 0.048 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Hemerythrin PF01814.18 KPI41035.1 - 4.8e-08 33.2 0.2 6.8e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF1378 PF07125.6 KPI41035.1 - 1.5 8.8 4.1 0.9 9.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1378) Thioredoxin PF00085.15 KPI41036.1 - 7e-06 25.6 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KPI41036.1 - 0.027 14.5 0.0 0.1 12.7 0.0 1.9 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.1 KPI41036.1 - 0.075 13.2 0.0 0.2 11.8 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain bZIP_1 PF00170.16 KPI41037.1 - 0.0018 18.1 6.1 0.003 17.5 4.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor Tape_meas_lam_C PF09718.5 KPI41038.1 - 0.16 11.9 0.5 1.7 8.6 0.1 2.0 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Glycoprotein_B PF00606.13 KPI41038.1 - 0.23 9.4 2.6 0.29 9.0 1.8 1.2 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B EspB PF05802.6 KPI41038.1 - 0.33 9.8 3.4 0.33 9.8 2.3 1.0 1 0 0 1 1 1 0 Enterobacterial EspB protein Chlorosome_CsmC PF11098.3 KPI41038.1 - 0.75 9.5 7.8 0.89 9.2 5.4 1.1 1 0 0 1 1 1 0 Chlorosome envelope protein C Entericidin PF08085.6 KPI41038.1 - 2.3 8.1 8.8 3.3 7.6 0.1 3.9 4 0 0 4 4 4 0 Entericidin EcnA/B family MFS_1 PF07690.11 KPI41039.1 - 1.5e-32 112.6 25.2 2.3e-32 112.1 17.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GP41 PF00517.12 KPI41039.1 - 0.053 13.0 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral envelope protein Cupin_8 PF13621.1 KPI41040.1 - 4.9e-15 55.7 0.1 8.3e-15 54.9 0.0 1.4 2 0 0 2 2 2 1 Cupin-like domain JmjC PF02373.17 KPI41040.1 - 5.8e-11 42.6 0.1 1.8e-10 41.0 0.1 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 KPI41040.1 - 0.068 12.3 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.6 KPI41040.1 - 0.12 11.9 0.0 0.64 9.5 0.0 2.0 2 0 0 2 2 2 0 Cupin domain DUF745 PF05335.8 KPI41041.1 - 0.039 13.4 0.3 0.055 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Mito_carr PF00153.22 KPI41042.1 - 2.4e-50 168.1 7.5 3.6e-17 61.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Dus PF01207.12 KPI41043.1 - 3.6e-39 134.4 0.0 2.6e-27 95.4 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 KPI41043.1 - 0.011 15.3 6.8 0.064 12.9 0.4 3.4 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KPI41043.1 - 0.47 10.5 5.0 0.63 10.1 1.2 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Lyase_1 PF00206.15 KPI41045.1 - 6e-38 130.7 0.1 3.5e-37 128.2 0.0 1.8 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.4 KPI41045.1 - 5.3e-25 87.2 0.1 1.2e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Acyl-CoA_dh_1 PF00441.19 KPI41046.1 - 2.6e-22 79.5 1.4 2.8e-22 79.4 0.3 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KPI41046.1 - 8.9e-13 48.8 0.1 2.2e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KPI41046.1 - 8.8e-08 31.5 0.0 1.7e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KPI41046.1 - 1.5e-06 28.4 0.0 2.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain adh_short PF00106.20 KPI41047.1 - 6.8e-15 55.3 1.4 6.9e-09 35.8 0.0 3.5 4 0 0 4 4 4 2 short chain dehydrogenase RmlD_sub_bind PF04321.12 KPI41047.1 - 1.1e-13 50.8 0.0 6.7e-13 48.1 0.0 2.3 2 1 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.16 KPI41047.1 - 3.9e-13 49.3 0.1 6.3e-12 45.4 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KPI41047.1 - 1e-08 35.0 0.1 0.0035 17.0 0.0 3.9 3 1 1 4 4 4 3 KR domain adh_short_C2 PF13561.1 KPI41047.1 - 8.9e-06 25.6 0.0 9.1e-05 22.3 0.0 2.3 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 KPI41047.1 - 0.00027 19.7 0.0 0.00067 18.4 0.0 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KPI41047.1 - 0.0011 17.9 0.0 0.0027 16.6 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Sp100 PF03172.8 KPI41049.1 - 0.12 12.3 0.0 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 Sp100 domain HTH_30 PF13556.1 KPI41049.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Imm31 PF15595.1 KPI41050.1 - 0.067 12.9 0.1 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 31 Adenylsucc_synt PF00709.16 KPI41051.1 - 1.9e-145 484.7 0.0 2.1e-145 484.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase MOZ_SAS PF01853.13 KPI41052.1 - 5.2e-49 166.0 0.0 8.5e-49 165.3 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family IF2_N PF04760.10 KPI41052.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region DUF1275 PF06912.6 KPI41053.1 - 9.9e-40 135.9 11.7 1.2e-39 135.7 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Fungal_trans_2 PF11951.3 KPI41054.1 - 0.00083 18.0 0.5 0.0048 15.5 0.3 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain ENTH PF01417.15 KPI41055.1 - 2.5e-45 153.3 0.0 4e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KPI41055.1 - 0.00021 20.0 0.0 0.0003 19.5 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 KPI41055.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 VHS domain GRP PF07172.6 KPI41055.1 - 8.4 6.9 23.3 9.7 6.7 15.2 1.7 2 0 0 2 2 2 0 Glycine rich protein family AAR2 PF05282.6 KPI41056.1 - 5.3e-64 216.4 0.0 1e-63 215.4 0.0 1.3 1 1 0 1 1 1 1 AAR2 protein RE_EcoO109I PF14511.1 KPI41056.1 - 0.18 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I Ndc80_HEC PF03801.8 KPI41057.1 - 2.3e-55 186.4 0.0 4.5e-55 185.4 0.0 1.4 1 0 0 1 1 1 1 HEC/Ndc80p family Reo_sigmaC PF04582.7 KPI41057.1 - 0.031 13.4 10.5 0.34 10.0 0.3 3.0 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Filament PF00038.16 KPI41057.1 - 0.13 11.6 40.7 0.014 14.8 14.0 2.9 2 1 0 2 2 2 0 Intermediate filament protein CENP-F_leu_zip PF10473.4 KPI41057.1 - 0.18 11.6 42.4 0.013 15.3 13.7 3.9 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KPI41057.1 - 0.62 9.6 32.8 0.28 10.7 4.2 3.5 2 1 1 3 3 3 0 IncA protein IF-2B PF01008.12 KPI41057.1 - 0.72 8.7 14.3 0.012 14.6 2.5 2.3 2 0 0 2 2 2 0 Initiation factor 2 subunit family V_ATPase_I PF01496.14 KPI41057.1 - 0.8 7.4 25.0 0.41 8.4 5.6 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TMCO5 PF14992.1 KPI41057.1 - 1.2 8.1 39.3 0.026 13.6 6.9 2.9 2 1 1 3 3 3 0 TMCO5 family DUF948 PF06103.6 KPI41057.1 - 1.4 8.8 17.0 0.088 12.6 1.0 4.3 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 KPI41057.1 - 2.3 8.4 15.6 6.4 7.0 0.4 4.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.6 KPI41057.1 - 3.7 6.9 41.2 1.4 8.3 5.7 3.4 2 1 1 3 3 3 0 Phage minor structural protein GP20 bZIP_1 PF00170.16 KPI41057.1 - 6 6.9 17.2 4.8 7.2 0.9 4.4 4 0 0 4 4 3 0 bZIP transcription factor DASH_Dad4 PF08650.5 KPI41057.1 - 6.3 6.7 7.5 2 8.3 0.6 3.3 3 0 0 3 3 3 0 DASH complex subunit Dad4 DUF3584 PF12128.3 KPI41057.1 - 7.3 3.7 34.6 0.81 6.9 6.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) WEMBL PF05701.6 KPI41057.1 - 7.9 4.8 43.5 4.4 5.6 10.4 2.6 2 2 0 2 2 2 0 Weak chloroplast movement under blue light Peptidase_S10 PF00450.17 KPI41059.1 - 1.7e-81 274.5 0.1 2.4e-81 274.0 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase ATG27 PF09451.5 KPI41059.1 - 5.1e-62 209.5 0.1 7.9e-62 208.9 0.1 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Peptidase_S28 PF05577.7 KPI41060.1 - 4.8e-50 170.3 0.4 1.3e-48 165.6 0.3 2.1 1 1 0 1 1 1 1 Serine carboxypeptidase S28 RseA_C PF03873.8 KPI41060.1 - 0.041 13.7 0.3 0.097 12.5 0.2 1.6 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Ten1 PF12658.2 KPI41061.1 - 4.7e-18 65.1 0.0 6.1e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Transp_cyt_pur PF02133.10 KPI41062.1 - 1.5e-97 326.9 42.5 1.9e-97 326.6 29.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Glyco_hydro_3 PF00933.16 KPI41063.1 - 6.8e-75 251.8 0.0 1.5e-74 250.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KPI41063.1 - 3.3e-47 160.8 0.0 6.9e-47 159.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KPI41063.1 - 9.5e-16 57.5 0.1 2.3e-15 56.2 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KPI41063.1 - 3.1e-09 36.6 0.4 5.7e-09 35.7 0.3 1.4 1 0 0 1 1 1 1 PA14 domain SHR3_chaperone PF08229.6 KPI41064.1 - 0.046 12.6 3.3 0.073 12.0 2.3 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 Bap31 PF05529.7 KPI41064.1 - 6.7 6.1 6.6 0.44 9.9 0.3 1.9 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like CTDII PF01556.13 KPI41065.1 - 5.3e-29 99.9 0.8 6e-22 77.3 0.1 3.4 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KPI41065.1 - 3.3e-10 39.5 1.2 7.2e-10 38.4 0.8 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KPI41065.1 - 6.4e-10 38.9 22.3 1.2e-09 38.0 15.4 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KPI41065.1 - 1.9 8.2 8.5 7.6 6.2 0.7 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family A2L_zn_ribbon PF08792.5 KPI41065.1 - 8.6 5.9 12.1 30 4.2 0.1 3.4 3 0 0 3 3 3 0 A2L zinc ribbon domain Metalloenzyme PF01676.13 KPI41066.1 - 1.3e-72 244.1 0.1 1.5e-72 243.9 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 KPI41066.1 - 6.2e-72 241.5 0.0 8.7e-72 241.0 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 KPI41066.1 - 5e-07 29.3 0.0 8.1e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KPI41066.1 - 1.9e-06 27.2 0.0 5.4e-05 22.5 0.0 2.4 1 1 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.15 KPI41066.1 - 0.0058 15.3 0.2 0.013 14.1 0.0 1.6 2 0 0 2 2 2 1 Alkaline phosphatase MIP-T3 PF10243.4 KPI41067.1 - 7.4e-05 21.4 2.3 7.7e-05 21.3 1.6 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Rifin_STEVOR PF02009.11 KPI41067.1 - 0.0017 18.0 5.4 0.0026 17.4 3.7 1.1 1 0 0 1 1 1 1 Rifin/stevor family AJAP1_PANP_C PF15298.1 KPI41067.1 - 0.0024 17.8 12.0 0.0048 16.8 8.3 1.5 1 0 0 1 1 1 1 AJAP1/PANP C-terminus VSP PF03302.8 KPI41067.1 - 0.0038 15.9 6.6 0.0053 15.4 4.6 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF966 PF06136.8 KPI41067.1 - 0.0076 15.6 4.8 0.0094 15.4 3.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF966) SAPS PF04499.10 KPI41067.1 - 0.042 12.4 0.5 0.046 12.3 0.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ndc1_Nup PF09531.5 KPI41067.1 - 0.045 12.1 4.9 0.059 11.8 3.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Plasmodium_Vir PF05795.6 KPI41067.1 - 0.069 12.3 3.0 0.086 12.0 2.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CDC45 PF02724.9 KPI41067.1 - 0.079 10.9 1.6 0.092 10.7 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Mem_trans PF03547.13 KPI41067.1 - 0.089 11.0 0.9 0.12 10.6 0.6 1.2 1 0 0 1 1 1 0 Membrane transport protein Hid1 PF12722.2 KPI41067.1 - 0.13 9.8 8.7 0.17 9.5 6.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.8 KPI41067.1 - 0.15 11.9 7.9 0.2 11.5 5.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2413 PF10310.4 KPI41067.1 - 0.39 9.4 13.9 0.52 9.0 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Strabismus PF06638.6 KPI41067.1 - 0.53 8.5 4.3 0.97 7.6 3.0 1.5 1 0 0 1 1 1 0 Strabismus protein TFIIF_alpha PF05793.7 KPI41067.1 - 1.5 7.1 21.1 2.1 6.6 14.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Podoplanin PF05808.6 KPI41067.1 - 1.6 8.2 19.0 0.16 11.5 9.9 1.7 2 0 0 2 2 2 0 Podoplanin TMEM154 PF15102.1 KPI41067.1 - 4.1 7.0 15.9 1.2e+02 2.3 11.0 2.2 1 1 0 1 1 1 0 TMEM154 protein family FAM60A PF15396.1 KPI41067.1 - 4.9 6.8 8.5 7.8 6.1 5.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Menin PF05053.8 KPI41067.1 - 9.3 4.2 8.8 12 3.9 6.1 1.1 1 0 0 1 1 1 0 Menin Fungal_trans PF04082.13 KPI41068.1 - 2.1e-13 49.7 0.2 4.1e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box-like PF12937.2 KPI41069.1 - 0.088 12.5 1.5 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 F-box-like IFT46_B_C PF12317.3 KPI41069.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal DUF3464 PF11947.3 KPI41069.1 - 0.19 11.2 0.8 0.38 10.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Na_Ca_ex PF01699.19 KPI41070.1 - 3.8e-41 139.9 31.2 8.1e-23 80.5 8.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SR-25 PF10500.4 KPI41070.1 - 0.013 14.9 5.4 0.021 14.3 3.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sld5 PF05916.6 KPI41071.1 - 1.3e-26 92.9 0.0 2e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein PBP1_TM PF14812.1 KPI41071.1 - 1.7 8.9 6.7 4.5 7.6 4.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Abdominal-A PF12407.3 KPI41071.1 - 7.6 6.1 10.2 16 5.0 7.1 1.5 1 0 0 1 1 1 0 Homeobox protein Sugar_tr PF00083.19 KPI41072.1 - 7e-95 318.2 22.3 8.6e-95 317.9 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI41072.1 - 2.8e-22 78.9 48.2 2.4e-19 69.2 15.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PPR_2 PF13041.1 KPI41073.1 - 8e-20 70.5 0.0 1.8e-12 47.0 0.0 3.0 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 KPI41073.1 - 3.2e-05 23.8 4.7 0.14 12.5 0.0 5.3 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 KPI41073.1 - 0.0003 20.5 6.0 0.0054 16.6 0.0 4.2 5 0 0 5 5 5 1 PPR repeat PPR_1 PF12854.2 KPI41073.1 - 0.0039 16.6 0.0 5.3 6.6 0.0 3.9 4 0 0 4 4 4 2 PPR repeat SAP18 PF06487.7 KPI41074.1 - 5.8e-33 113.2 0.0 7.1e-33 112.9 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Pro_isomerase PF00160.16 KPI41075.1 - 1.4e-42 145.4 0.5 1.8e-42 145.1 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TFIIA PF03153.8 KPI41076.1 - 6.6 6.5 9.3 8.4 6.1 6.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YCII PF03795.9 KPI41077.1 - 3.4e-09 36.7 0.0 3.7e-09 36.6 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain DUF4019 PF13211.1 KPI41078.1 - 0.012 15.8 3.2 0.094 12.9 0.9 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4019) HMGL-like PF00682.14 KPI41078.1 - 0.022 14.4 4.5 0.048 13.3 2.7 1.9 1 1 0 1 1 1 0 HMGL-like V_ATPase_I PF01496.14 KPI41078.1 - 0.51 8.1 2.5 4.9 4.8 0.4 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Nitr_red_assoc PF09655.5 KPI41078.1 - 1.5 9.1 5.6 3.3 8.0 0.1 3.2 2 1 1 3 3 3 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) SRP19 PF01922.12 KPI41080.1 - 1.2e-18 67.4 0.0 2.3e-18 66.5 0.0 1.4 1 1 0 1 1 1 1 SRP19 protein HpaP PF09483.5 KPI41081.1 - 0.84 9.5 6.2 0.69 9.8 2.8 1.7 1 1 1 2 2 2 0 Type III secretion protein (HpaP) Paf67 PF10255.4 KPI41082.1 - 4.8e-139 463.7 0.0 1.4e-136 455.6 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 UDPGP PF01704.13 KPI41083.1 - 1.3e-55 188.5 0.0 1.8e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KPI41083.1 - 0.035 14.1 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 MobA-like NTP transferase domain Fer4_20 PF14691.1 KPI41083.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Amidase PF01425.16 KPI41085.1 - 9.8e-91 304.7 0.0 1.8e-90 303.9 0.0 1.4 1 1 0 1 1 1 1 Amidase Beta-lactamase PF00144.19 KPI41086.1 - 1.6e-36 126.0 0.1 2.4e-36 125.3 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.1 KPI41086.1 - 0.11 11.9 0.0 4.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase enzyme family SSDP PF04503.8 KPI41086.1 - 0.17 11.6 0.0 0.33 10.6 0.0 1.4 1 1 0 1 1 1 0 Single-stranded DNA binding protein, SSDP PLDc_2 PF13091.1 KPI41087.1 - 1.1e-19 70.4 0.0 1.3e-09 37.8 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KPI41087.1 - 1.3e-05 24.8 0.0 0.012 15.3 0.0 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif Fungal_trans PF04082.13 KPI41088.1 - 7.7e-11 41.3 0.5 1.2e-10 40.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF945 PF06097.6 KPI41088.1 - 0.15 10.7 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Fungal_trans_2 PF11951.3 KPI41089.1 - 1.9e-28 99.1 0.1 2.3e-28 98.9 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain TRI12 PF06609.8 KPI41091.1 - 1.2e-61 208.7 21.1 1.4e-61 208.4 14.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI41091.1 - 4.1e-24 84.9 57.1 7.9e-24 84.0 32.6 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI41091.1 - 1.8e-13 49.8 11.9 1.8e-13 49.8 8.3 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter DUF4131 PF13567.1 KPI41091.1 - 0.23 10.8 0.0 0.23 10.8 0.0 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Aminotran_5 PF00266.14 KPI41092.1 - 6.7e-10 38.2 0.0 2.9e-09 36.1 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Methyltransf_16 PF10294.4 KPI41094.1 - 6.6e-20 71.2 0.0 5.5e-19 68.2 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KPI41094.1 - 1.7e-05 24.2 0.0 3.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KPI41094.1 - 5.4e-05 22.9 0.0 0.00028 20.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI41094.1 - 0.00026 21.5 0.2 0.00071 20.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KPI41094.1 - 0.0003 20.0 0.0 0.0005 19.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 KPI41094.1 - 0.00046 20.6 0.1 0.0028 18.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 KPI41094.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 KPI41094.1 - 0.002 18.1 0.1 0.0047 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KPI41094.1 - 0.018 14.6 0.0 0.057 13.0 0.0 1.7 1 1 1 2 2 2 0 Met-10+ like-protein RrnaAD PF00398.15 KPI41094.1 - 0.044 12.8 0.0 0.099 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 KPI41094.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KPI41094.1 - 0.073 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PC4 PF02229.11 KPI41095.1 - 0.024 13.8 0.4 0.049 12.8 0.3 1.5 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) Acetyltransf_1 PF00583.19 KPI41096.1 - 2.6e-05 24.1 0.0 4.9e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI41096.1 - 0.00014 21.9 0.0 0.00022 21.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 KPI41096.1 - 0.0011 19.4 0.0 0.0032 17.9 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI41096.1 - 0.0035 17.4 0.0 0.0059 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KPI41096.1 - 0.027 14.2 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein zf-MYND PF01753.13 KPI41098.1 - 2.9e-12 46.2 9.1 4.7e-12 45.5 6.3 1.3 1 0 0 1 1 1 1 MYND finger PRP21_like_P PF12230.3 KPI41099.1 - 0.41 10.1 11.8 0.022 14.2 1.2 3.2 2 1 1 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein DnaJ PF00226.26 KPI41100.1 - 1.2e-17 63.3 0.9 2.6e-17 62.2 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain Ima1_N PF09779.4 KPI41100.1 - 0.0031 17.9 1.9 0.076 13.5 0.1 2.4 2 0 0 2 2 2 1 Ima1 N-terminal domain zf-C2H2_4 PF13894.1 KPI41101.1 - 3.6e-05 23.7 10.3 0.14 12.5 0.6 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KPI41101.1 - 0.0045 17.0 5.6 0.034 14.3 0.6 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KPI41101.1 - 0.0098 16.1 14.9 0.35 11.2 0.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KPI41101.1 - 0.014 15.6 0.9 0.014 15.6 0.6 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 KPI41101.1 - 0.023 14.5 0.8 0.023 14.5 0.5 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger KfrA_N PF11740.3 KPI41101.1 - 0.75 10.2 7.0 0.76 10.2 2.3 2.4 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term PAT1 PF09770.4 KPI41101.1 - 6.8 4.7 27.8 16 3.5 19.3 1.6 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Radical_SAM PF04055.16 KPI41102.1 - 9.3e-06 25.9 5.2 0.00079 19.6 0.0 2.4 1 1 1 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.1 KPI41102.1 - 0.0028 17.7 4.0 0.093 12.8 0.0 2.3 1 1 1 2 2 2 2 4Fe-4S single cluster domain Fer4_14 PF13394.1 KPI41102.1 - 0.0077 16.2 4.8 0.48 10.4 0.0 2.7 1 1 1 2 2 2 1 4Fe-4S single cluster domain PHD PF00628.24 KPI41103.1 - 5.1e-05 22.8 5.2 0.0001 21.9 3.6 1.6 1 0 0 1 1 1 1 PHD-finger Gp49 PF05973.9 KPI41103.1 - 0.0033 17.3 0.0 0.091 12.7 0.0 2.4 2 0 0 2 2 2 1 Phage derived protein Gp49-like (DUF891) Methyltransf_11 PF08241.7 KPI41104.1 - 1.8e-12 47.5 0.0 3.7e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI41104.1 - 3.6e-11 43.3 0.0 1.8e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI41104.1 - 1.4e-07 31.2 0.0 2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI41104.1 - 5e-07 30.2 0.0 4e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI41104.1 - 1.8e-06 27.7 0.0 3.8e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI41104.1 - 2.6e-06 27.7 0.0 4.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI41104.1 - 2.4e-05 24.3 0.4 0.00022 21.2 0.2 2.5 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI41104.1 - 0.00088 18.4 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PilJ PF13675.1 KPI41104.1 - 0.036 14.3 0.5 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term VPS9 PF02204.13 KPI41105.1 - 2e-26 92.0 0.0 4e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF2360 PF10152.4 KPI41105.1 - 0.025 14.8 0.7 0.025 14.8 0.5 4.0 3 1 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) AMP-binding PF00501.23 KPI41106.1 - 2.4e-83 279.8 0.0 3.1e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI41106.1 - 1e-10 42.4 2.1 1.1e-10 42.3 0.3 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Aldo_ket_red PF00248.16 KPI41107.1 - 1.5e-46 158.5 0.0 1.7e-46 158.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Nuc_N PF14448.1 KPI41107.1 - 0.0032 16.9 0.0 0.7 9.4 0.0 2.4 2 0 0 2 2 2 2 Nuclease N terminal MFS_1 PF07690.11 KPI41108.1 - 3.2e-21 75.4 27.4 9e-18 64.0 7.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KPI41109.1 - 2.5e-31 108.6 67.0 7.5e-30 103.8 29.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI41109.1 - 0.0039 15.8 38.0 0.0063 15.1 5.5 3.5 3 1 1 4 4 4 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI41110.1 - 6e-36 123.8 53.5 3e-32 111.7 27.7 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Antimicrobial10 PF08105.6 KPI41110.1 - 0.0049 16.4 0.2 0.027 14.1 0.1 2.3 1 0 0 1 1 1 1 Metchnikowin family adh_short PF00106.20 KPI41111.1 - 9.3e-18 64.6 0.4 1.4e-17 64.1 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI41111.1 - 2.4e-08 34.0 0.1 3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 KPI41111.1 - 0.00028 20.2 0.6 0.00057 19.2 0.3 1.5 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 KPI41111.1 - 0.00034 20.3 0.4 0.00052 19.7 0.3 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI41111.1 - 0.00053 20.0 0.8 0.0082 16.1 0.1 2.5 2 1 1 3 3 3 1 NADH(P)-binding Viral_protease PF08715.5 KPI41111.1 - 0.011 14.7 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Papain like viral protease Epimerase PF01370.16 KPI41111.1 - 0.031 13.7 0.1 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Ribosomal_L13 PF00572.13 KPI41112.1 - 6e-11 42.5 0.0 7.5e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S11 PF00411.14 KPI41113.1 - 1.4e-40 137.8 0.5 1.8e-40 137.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 KPI41113.1 - 0.044 12.6 0.0 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Pex14_N PF04695.8 KPI41114.1 - 6.4e-30 103.9 4.4 6.4e-30 103.9 3.1 4.1 2 2 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region BicD PF09730.4 KPI41114.1 - 0.00019 19.9 0.3 0.00023 19.6 0.2 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D zf-C4H2 PF10146.4 KPI41114.1 - 0.0022 18.0 8.4 0.0022 18.0 5.8 2.3 1 1 1 2 2 2 1 Zinc finger-containing protein DUF737 PF05300.6 KPI41114.1 - 0.0082 16.1 0.4 0.0082 16.1 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF737) HAUS-augmin3 PF14932.1 KPI41114.1 - 0.013 14.6 2.7 0.026 13.7 1.9 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF724 PF05266.9 KPI41114.1 - 0.028 14.0 3.5 0.044 13.3 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) AIP3 PF03915.8 KPI41114.1 - 0.05 12.5 4.6 0.11 11.3 1.8 1.8 1 1 1 2 2 2 0 Actin interacting protein 3 ATP-synt_B PF00430.13 KPI41114.1 - 0.053 13.3 4.3 0.11 12.3 2.9 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF4164 PF13747.1 KPI41114.1 - 0.067 13.3 0.3 0.067 13.3 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) DUF848 PF05852.6 KPI41114.1 - 0.071 12.9 5.3 0.16 11.8 3.7 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) FliD_N PF02465.13 KPI41114.1 - 0.078 13.3 1.9 0.18 12.2 0.3 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TPR_MLP1_2 PF07926.7 KPI41114.1 - 0.12 12.0 7.2 0.096 12.4 1.6 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 KPI41114.1 - 0.13 11.8 8.4 0.25 10.9 5.8 1.4 1 0 0 1 1 1 0 IncA protein DUF3708 PF12501.3 KPI41114.1 - 0.18 11.6 0.6 0.35 10.7 0.4 1.4 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Baculo_PEP_C PF04513.7 KPI41114.1 - 0.2 11.4 5.7 4.2 7.1 4.0 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1043 PF06295.7 KPI41114.1 - 0.23 11.1 1.1 0.58 9.8 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) ERM PF00769.14 KPI41114.1 - 0.34 10.4 9.9 0.18 11.2 4.7 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family TBPIP PF07106.8 KPI41114.1 - 0.35 10.3 6.4 0.55 9.7 1.6 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 KPI41114.1 - 0.61 10.2 3.8 1.2 9.2 2.6 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FlgN PF05130.7 KPI41114.1 - 0.66 10.2 6.5 1.2 9.3 4.5 1.3 1 0 0 1 1 1 0 FlgN protein CALCOCO1 PF07888.6 KPI41114.1 - 0.73 8.0 6.8 1.1 7.4 4.7 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like SlyX PF04102.7 KPI41114.1 - 0.77 10.1 3.9 0.89 9.9 0.7 2.6 2 1 0 2 2 2 0 SlyX DUF3584 PF12128.3 KPI41114.1 - 1.2 6.4 12.3 0.075 10.3 5.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF4404 PF14357.1 KPI41114.1 - 1.2 9.5 6.8 1.1 9.7 3.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Fzo_mitofusin PF04799.8 KPI41114.1 - 1.5 8.1 3.9 6.9 6.0 1.5 2.2 1 1 1 2 2 2 0 fzo-like conserved region Bacillus_HBL PF05791.6 KPI41114.1 - 2.2 7.6 6.8 1.1 8.6 2.2 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF148 PF02520.12 KPI41114.1 - 3 7.6 6.7 1.3 8.8 2.8 1.7 2 0 0 2 2 1 0 Domain of unknown function DUF148 YkyA PF10368.4 KPI41114.1 - 5.5 6.2 10.6 2 7.7 5.3 1.6 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein DUF1664 PF07889.7 KPI41114.1 - 6.7 6.5 5.7 10 5.9 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) XhlA PF10779.4 KPI41114.1 - 8.5 6.3 9.7 1.5 8.7 1.5 2.6 1 1 2 3 3 3 0 Haemolysin XhlA F-box PF00646.28 KPI41116.1 - 0.0027 17.3 1.3 0.0042 16.7 0.2 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KPI41116.1 - 0.015 14.9 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 F-box-like ApbA_C PF08546.6 KPI41117.1 - 4.4e-26 91.3 0.0 7.7e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KPI41117.1 - 6.4e-16 58.1 0.4 2.8e-14 52.8 0.0 2.3 1 1 1 2 2 2 2 Ketopantoate reductase PanE/ApbA DIOX_N PF14226.1 KPI41118.1 - 2.3e-27 95.8 0.0 3.4e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI41118.1 - 2.4e-21 75.8 0.0 3.8e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily F-box PF00646.28 KPI41119.1 - 0.0023 17.5 0.0 0.0079 15.8 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KPI41119.1 - 0.069 12.8 0.2 0.5 10.1 0.0 2.2 2 0 0 2 2 2 0 F-box-like HAD_2 PF13419.1 KPI41120.1 - 1.4e-23 84.0 0.0 2.1e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KPI41120.1 - 1.6e-05 25.4 0.0 2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KPI41120.1 - 0.046 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like DUF1349 PF07081.6 KPI41121.1 - 5.1e-27 94.4 0.0 5.8e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Mo-co_dimer PF03404.11 KPI41121.1 - 0.052 13.1 0.3 0.086 12.4 0.2 1.3 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain PIGA PF08288.7 KPI41122.1 - 1.8e-45 153.2 1.9 5e-45 151.7 1.3 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 KPI41122.1 - 1.7e-26 92.6 0.0 2.5e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KPI41122.1 - 7.7e-16 58.3 0.5 1.4e-15 57.4 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KPI41122.1 - 1.2e-14 54.5 0.1 2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KPI41122.1 - 9e-12 45.4 0.0 2.1e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KPI41122.1 - 9e-05 22.6 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 KPI41122.1 - 0.00016 21.5 0.2 0.00039 20.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like DUF3438 PF11920.3 KPI41123.1 - 0.014 14.2 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) Cupin_2 PF07883.6 KPI41124.1 - 1e-08 34.5 0.2 1.9e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Paf1 PF03985.8 KPI41126.1 - 3.8e-24 85.2 6.7 4.7e-24 84.9 0.0 2.8 2 1 0 2 2 2 1 Paf1 4HBT_3 PF13622.1 KPI41126.1 - 0.027 14.1 0.4 0.068 12.9 0.3 1.7 1 0 0 1 1 1 0 Thioesterase-like superfamily Amidase PF01425.16 KPI41127.1 - 8.9e-79 265.3 0.0 1.2e-78 264.9 0.0 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 KPI41128.1 - 8.2e-25 87.2 39.3 7.4e-15 54.5 10.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI41128.1 - 5.2e-20 71.4 18.2 7.9e-20 70.8 12.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Acetyltransf_1 PF00583.19 KPI41129.1 - 6.8e-11 42.0 0.0 1.6e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI41129.1 - 4.8e-06 26.6 0.0 8.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI41129.1 - 0.00038 20.5 0.0 0.0014 18.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KPI41129.1 - 0.0014 18.3 0.0 0.0033 17.1 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KPI41129.1 - 0.014 15.2 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KPI41129.1 - 0.02 15.0 0.1 0.098 12.8 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF619 PF04768.8 KPI41129.1 - 0.081 12.3 0.1 0.19 11.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF619) Acetyltransf_CG PF14542.1 KPI41129.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pol_alpha_B_N PF08418.5 KPI41130.1 - 0.072 12.6 3.9 0.11 11.9 2.7 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal CPSF73-100_C PF11718.3 KPI41131.1 - 1.1e-68 230.8 0.0 1.6e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KPI41131.1 - 2.9e-31 108.0 0.0 1.1e-30 106.1 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 KPI41131.1 - 9.9e-15 54.6 0.3 2e-14 53.7 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI41131.1 - 5.8e-10 39.0 0.1 5.8e-10 39.0 0.1 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KPI41131.1 - 1.6e-07 30.9 0.1 3.5e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 KPI41131.1 - 1.7e-05 24.5 0.1 1.7e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain adh_short PF00106.20 KPI41132.1 - 1.3e-14 54.5 0.0 4.8e-13 49.3 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI41132.1 - 0.00012 21.9 0.0 0.0012 18.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KPI41132.1 - 0.0031 17.0 0.0 0.0089 15.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KPI41132.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 KR domain Methyltransf_18 PF12847.2 KPI41132.1 - 0.053 14.1 0.0 0.098 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CN_hydrolase PF00795.17 KPI41134.1 - 6.1e-25 87.6 0.0 9.2e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.13 KPI41135.1 - 1.1e-22 80.1 0.0 2e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI41135.1 - 8.3e-05 22.4 10.1 0.00016 21.5 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA-synt_1g PF09334.6 KPI41135.1 - 0.23 10.0 0.4 0.49 9.0 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (M) COX17 PF05051.8 KPI41135.1 - 4.3 7.4 7.6 12 6.0 5.3 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) R3H PF01424.17 KPI41136.1 - 0.11 12.1 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 R3H domain adh_short PF00106.20 KPI41137.1 - 2e-08 34.3 0.0 2.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Plug_translocon PF10559.4 KPI41137.1 - 0.01 15.3 0.1 0.034 13.6 0.0 1.9 2 0 0 2 2 2 0 Plug domain of Sec61p RTA1 PF04479.8 KPI41138.1 - 4.9e-42 143.9 3.2 6.3e-42 143.5 2.2 1.1 1 0 0 1 1 1 1 RTA1 like protein OCIA PF07051.6 KPI41138.1 - 0.031 13.6 0.2 0.056 12.8 0.1 1.4 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) GWT1 PF06423.7 KPI41140.1 - 3e-33 114.8 0.4 3e-33 114.8 0.2 2.5 2 0 0 2 2 2 1 GWT1 NNMT_PNMT_TEMT PF01234.12 KPI41140.1 - 0.16 10.8 0.0 0.42 9.5 0.0 1.6 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Sec62 PF03839.11 KPI41140.1 - 0.44 9.9 1.9 3.8 6.8 0.0 2.6 3 0 0 3 3 3 0 Translocation protein Sec62 Sulfatase PF00884.18 KPI41141.1 - 2.3e-60 204.3 0.7 3.4e-60 203.8 0.5 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KPI41141.1 - 1.3 8.2 6.0 0.86 8.8 2.0 2.1 2 1 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1664 PF07889.7 KPI41142.1 - 0.0033 17.2 7.9 0.19 11.5 0.5 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) DUF4404 PF14357.1 KPI41142.1 - 0.11 12.9 5.7 0.53 10.7 0.2 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF3584 PF12128.3 KPI41142.1 - 0.28 8.4 8.6 0.43 7.8 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MerR-DNA-bind PF09278.6 KPI41142.1 - 0.39 11.1 5.2 1.7 9.1 0.5 3.0 2 0 0 2 2 2 0 MerR, DNA binding CENP-F_leu_zip PF10473.4 KPI41142.1 - 0.41 10.5 8.1 5.6 6.8 5.6 2.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4618 PF15397.1 KPI41142.1 - 0.78 9.0 6.7 18 4.5 3.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DivIC PF04977.10 KPI41142.1 - 2.1 7.9 5.4 2.7 7.5 0.7 3.0 3 0 0 3 3 3 0 Septum formation initiator Cluap1 PF10234.4 KPI41142.1 - 3.1 6.9 7.8 6 5.9 5.4 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 FlxA PF14282.1 KPI41142.1 - 4.2 7.3 16.6 1.2 9.1 1.7 2.9 1 1 0 2 2 2 0 FlxA-like protein ADIP PF11559.3 KPI41142.1 - 5.1 6.9 10.9 14 5.5 0.5 2.7 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 KPI41142.1 - 5.6 5.5 8.5 15 4.1 5.7 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Fe-S_biosyn PF01521.15 KPI41143.1 - 1.1e-09 38.1 0.0 4.9e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Pol_alpha_B_N PF08418.5 KPI41143.1 - 6.6 6.1 6.8 9.7 5.6 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Mg_trans_NIPA PF05653.9 KPI41144.1 - 1.3e-103 346.0 8.4 1.7e-103 345.7 5.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KPI41144.1 - 3e-08 33.8 4.2 3e-08 33.8 2.9 3.1 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 KPI41144.1 - 9.2e-05 22.4 8.5 9.2e-05 22.4 5.9 3.1 2 1 1 3 3 3 2 EamA-like transporter family DUF3487 PF11990.3 KPI41144.1 - 1.3 8.4 0.0 1.3 8.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) PDR_assoc PF08370.6 KPI41144.1 - 2.6 7.6 6.9 7 6.2 0.3 2.7 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Pyr_redox_3 PF13738.1 KPI41145.1 - 6.8e-24 85.0 0.0 1.7e-23 83.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI41145.1 - 1.7e-21 76.0 0.2 2.2e-18 65.7 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI41145.1 - 1.9e-11 43.7 0.0 4.7e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI41145.1 - 2e-08 33.5 0.0 0.00014 20.9 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KPI41145.1 - 1.9e-05 24.5 0.0 0.00042 20.1 0.0 2.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KPI41145.1 - 0.011 14.6 0.0 1.3 7.8 0.0 2.8 2 1 1 3 3 3 0 FAD dependent oxidoreductase mRNA_cap_C PF03919.10 KPI41145.1 - 0.069 13.4 0.5 0.18 12.1 0.3 1.6 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Shikimate_DH PF01488.15 KPI41145.1 - 0.14 12.2 0.0 0.63 10.1 0.0 2.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF566 PF04484.7 KPI41146.1 - 4.4 6.7 9.5 6.3 6.2 6.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ribosomal_S24e PF01282.14 KPI41147.1 - 1.4e-34 117.6 0.1 2.7e-34 116.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e NAP PF00956.13 KPI41148.1 - 7.4e-31 107.1 0.1 1.3e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Nol1_Nop2_Fmu PF01189.12 KPI41149.1 - 2e-18 66.8 0.0 9.6e-11 41.5 0.0 2.9 3 0 0 3 3 3 2 NOL1/NOP2/sun family Trypan_PARP PF05887.6 KPI41149.1 - 0.045 13.5 2.8 2.7 7.8 1.7 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF4200 PF13863.1 KPI41149.1 - 0.08 12.8 0.7 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Transferase PF02458.10 KPI41150.1 - 1.2e-10 40.4 0.0 7.3e-10 37.8 0.0 1.9 1 1 0 1 1 1 1 Transferase family DUF4185 PF13810.1 KPI41151.1 - 1.8e-13 50.0 0.2 3.4e-13 49.1 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4185) SKG6 PF08693.5 KPI41152.1 - 1.8e-07 30.3 0.2 3.2e-07 29.5 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1180 PF06679.7 KPI41152.1 - 5.4e-05 23.1 0.1 0.00013 21.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Podoplanin PF05808.6 KPI41152.1 - 0.0013 18.2 0.1 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Podoplanin Alpha_GJ PF03229.8 KPI41152.1 - 0.0014 19.0 6.8 0.0026 18.0 4.7 1.4 1 0 0 1 1 1 1 Alphavirus glycoprotein J Plasmodium_Vir PF05795.6 KPI41152.1 - 0.0024 17.1 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Herpes_gE PF02480.11 KPI41152.1 - 0.0026 16.0 0.0 0.0039 15.5 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Rax2 PF12768.2 KPI41152.1 - 0.014 14.6 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TMEM51 PF15345.1 KPI41152.1 - 0.036 13.7 0.1 0.081 12.6 0.0 1.6 1 1 1 2 2 2 0 Transmembrane protein 51 CcmD PF04995.9 KPI41152.1 - 0.23 11.2 1.9 0.44 10.3 1.3 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Pex14_N PF04695.8 KPI41152.1 - 7 6.6 7.2 0.37 10.8 1.2 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hamartin PF04388.7 KPI41152.1 - 9.8 4.7 8.8 13 4.3 6.1 1.1 1 0 0 1 1 1 0 Hamartin protein Pex2_Pex12 PF04757.9 KPI41153.1 - 2e-38 132.1 7.2 2.6e-38 131.7 5.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 KPI41153.1 - 0.013 15.3 4.5 0.029 14.2 3.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_clus PF00172.13 KPI41154.1 - 2.9e-09 36.6 9.3 5.8e-09 35.7 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KPI41154.1 - 0.046 12.5 0.1 0.081 11.7 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain ABC_tran PF00005.22 KPI41155.1 - 9e-35 119.9 0.0 1.7e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KPI41155.1 - 4.4e-09 36.1 10.2 8e-09 35.2 7.0 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KPI41155.1 - 2.3e-05 23.7 0.2 0.00036 19.8 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KPI41155.1 - 0.0022 18.0 0.0 0.056 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KPI41155.1 - 0.01 16.1 0.3 0.018 15.3 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KPI41155.1 - 0.012 15.7 0.0 0.039 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KPI41155.1 - 0.014 14.8 0.2 0.046 13.2 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain FAM176 PF14851.1 KPI41155.1 - 0.018 14.6 2.3 0.17 11.5 0.0 2.8 3 0 0 3 3 2 0 FAM176 family DUF1049 PF06305.6 KPI41155.1 - 0.019 14.4 3.0 0.3 10.6 0.3 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DUF258 PF03193.11 KPI41155.1 - 0.026 13.7 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Herpes_gE PF02480.11 KPI41155.1 - 0.08 11.1 2.2 0.31 9.2 0.0 2.4 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E Aminotran_1_2 PF00155.16 KPI41156.1 - 1.2e-19 70.4 0.0 1.5e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KPI41156.1 - 0.06 11.8 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase DNA_pol_A_exo1 PF01612.15 KPI41157.1 - 6e-28 97.5 0.4 8.9e-20 70.8 0.0 2.4 1 1 1 2 2 2 2 3'-5' exonuclease PMC2NT PF08066.7 KPI41157.1 - 4.7e-25 87.6 0.2 1.1e-24 86.5 0.1 1.6 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 KPI41157.1 - 6.5e-12 44.9 0.0 1.8e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 HRDC domain G-patch PF01585.18 KPI41158.1 - 5.6e-13 48.4 2.1 1.5e-12 47.1 1.4 1.7 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 KPI41158.1 - 1.3e-05 24.9 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KPI41158.1 - 0.00034 20.1 0.0 0.00076 19.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI41158.1 - 0.0041 17.0 0.0 0.008 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Amidase PF01425.16 KPI41159.1 - 4e-66 223.7 0.1 5.1e-66 223.3 0.1 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.15 KPI41159.1 - 2.1e-41 141.7 0.0 3.3e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Spot_14 PF07084.7 KPI41160.1 - 0.045 13.6 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 F-box-like_2 PF13013.1 KPI41160.1 - 0.058 13.1 0.2 0.88 9.3 0.2 2.6 1 1 0 1 1 1 0 F-box-like domain Apolipoprotein PF01442.13 KPI41161.1 - 0.015 14.8 2.2 0.022 14.2 1.6 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2514 PF10721.4 KPI41161.1 - 0.062 13.0 13.3 0.093 12.4 9.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) DMPK_coil PF08826.5 KPI41161.1 - 0.084 12.7 2.3 0.16 11.8 1.6 1.6 1 0 0 1 1 1 0 DMPK coiled coil domain like Phage_Gp19 PF09355.5 KPI41161.1 - 0.39 10.5 2.4 4.6 7.1 0.1 2.3 1 1 1 2 2 2 0 Phage protein Gp19/Gp15/Gp42 DUF4407 PF14362.1 KPI41161.1 - 0.44 9.4 10.6 0.54 9.1 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2317 PF10079.4 KPI41161.1 - 1.8 7.0 6.0 2.1 6.8 4.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF1906 PF08924.6 KPI41161.1 - 2.5 7.9 7.2 16 5.3 5.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1906) DUF1423 PF07227.6 KPI41161.1 - 2.6 6.5 6.3 3.3 6.2 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) DUF883 PF05957.8 KPI41161.1 - 4.4 7.7 14.9 0.79 10.1 6.8 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.13 KPI41161.1 - 8.8 6.1 19.9 2.5 7.9 8.7 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF3405 PF11885.3 KPI41162.1 - 3.2e-136 454.4 5.1 4.2e-130 434.2 1.6 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) HisKA_2 PF07568.7 KPI41163.1 - 0.016 15.0 0.1 0.18 11.6 0.0 2.3 1 1 0 2 2 2 0 Histidine kinase ADH_zinc_N_2 PF13602.1 KPI41164.1 - 3.2e-11 44.2 0.0 5.7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Acyl_transf_3 PF01757.17 KPI41165.1 - 3.2e-31 108.4 31.4 3.8e-31 108.1 21.8 1.1 1 0 0 1 1 1 1 Acyltransferase family eRF1_1 PF03463.10 KPI41166.1 - 2e-44 150.3 0.1 4.1e-44 149.3 0.0 1.6 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_2 PF03464.10 KPI41166.1 - 9.1e-23 81.0 0.0 1.3e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KPI41166.1 - 1.6e-20 73.4 0.0 3.1e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 Chitin_synth_1 PF01644.12 KPI41167.1 - 9.7e-85 282.3 0.0 1.4e-84 281.8 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KPI41167.1 - 2.4e-31 107.2 1.7 2.6e-31 107.1 0.1 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KPI41167.1 - 7.4e-21 74.1 0.1 2.6e-19 69.0 0.0 2.2 1 1 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KPI41167.1 - 3.2e-07 30.2 4.5 1.1e-06 28.4 3.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KPI41167.1 - 7.2e-05 22.6 0.0 0.0003 20.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 CUE PF02845.11 KPI41168.1 - 2.8e-08 33.0 0.0 4.1e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain Fungal_trans_2 PF11951.3 KPI41169.1 - 9.2e-05 21.1 0.1 0.0001 21.0 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Metallopep PF12044.3 KPI41172.1 - 8.7e-166 551.5 0.0 1.1e-165 551.2 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 KPI41172.1 - 0.00018 21.3 0.7 0.019 14.8 0.0 2.2 2 1 1 3 3 3 2 Jacalin-like lectin domain Reprolysin_5 PF13688.1 KPI41172.1 - 0.016 15.1 0.2 0.034 14.0 0.2 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KPI41172.1 - 0.028 14.4 0.1 0.06 13.4 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KPI41172.1 - 0.18 12.3 0.4 0.4 11.2 0.3 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DPBB_1 PF03330.13 KPI41173.1 - 0.0084 16.0 0.1 0.023 14.7 0.0 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KPI41173.1 - 0.022 14.4 0.2 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 Barwin family DUF605 PF04652.11 KPI41173.1 - 3 7.1 16.2 3.6 6.8 11.2 1.1 1 0 0 1 1 1 0 Vta1 like DUF3659 PF12396.3 KPI41174.1 - 2.1e-286 924.1 174.9 6.2e-24 83.4 1.6 13.7 13 0 0 13 13 13 13 Protein of unknown function (DUF3659) DUF883 PF05957.8 KPI41174.1 - 0.00076 19.8 52.7 0.21 12.0 0.8 8.5 7 2 2 9 9 9 5 Bacterial protein of unknown function (DUF883) GSP_synth PF03738.9 KPI41174.1 - 0.26 11.5 14.8 3.9 7.7 0.1 8.6 9 1 0 10 10 10 0 Glutathionylspermidine synthase preATP-grasp DUF2892 PF11127.3 KPI41174.1 - 9.2 6.1 6.7 19 5.2 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) Synaptobrevin PF00957.16 KPI41175.1 - 1.1e-14 53.7 0.8 1.8e-14 53.1 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KPI41175.1 - 4.8e-14 51.6 0.1 8.4e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain ATP-synt_D PF01813.12 KPI41175.1 - 0.03 13.8 0.2 0.044 13.3 0.1 1.3 1 0 0 1 1 1 0 ATP synthase subunit D Tbf5 PF06331.7 KPI41175.1 - 0.055 13.2 0.4 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Homez PF11569.3 KPI41175.1 - 0.12 11.4 0.1 4.4 6.4 0.1 2.6 2 1 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Transket_pyr PF02779.19 KPI41177.1 - 2.2e-48 164.0 0.0 3.3e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KPI41177.1 - 4.8e-35 120.2 0.2 1.1e-34 118.9 0.1 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DAGK_cat PF00781.19 KPI41178.1 - 4.1e-06 26.2 0.0 7.5e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF1609 PF07753.6 KPI41178.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) TFIIA PF03153.8 KPI41179.1 - 6.8 6.4 19.8 9.5 6.0 13.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Oxysterol_BP PF01237.13 KPI41180.1 - 7.6e-89 297.6 0.0 1.1e-88 297.1 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein DOMON PF03351.12 KPI41181.1 - 1.3e-11 44.5 0.3 2.4e-11 43.6 0.2 1.5 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 KPI41181.1 - 7.8e-07 29.0 9.0 1.4e-06 28.1 6.3 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KPI41181.1 - 0.00034 20.1 1.9 0.00066 19.2 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) EphA2_TM PF14575.1 KPI41181.1 - 0.2 12.0 0.0 0.9 9.9 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Clr5 PF14420.1 KPI41182.1 - 1.6e-06 27.8 7.6 1.6e-06 27.8 5.3 1.8 2 0 0 2 2 2 1 Clr5 domain NIF PF03031.13 KPI41183.1 - 3.9e-27 94.8 0.0 7.2e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pyr_redox_3 PF13738.1 KPI41184.1 - 3.4e-17 63.1 0.0 9.9e-17 61.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI41184.1 - 1.4e-10 41.0 0.0 3.5e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KPI41184.1 - 5.2e-10 38.1 0.2 1.2e-07 30.3 0.0 2.8 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 KPI41184.1 - 9.2e-06 25.5 0.1 8.1e-05 22.4 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KPI41184.1 - 8.4e-05 21.6 0.0 0.095 11.6 0.0 3.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KPI41184.1 - 0.029 13.4 0.0 0.067 12.2 0.0 1.5 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 KPI41184.1 - 0.036 12.9 0.0 0.083 11.7 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KPI41184.1 - 0.079 11.4 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 KPI41184.1 - 0.17 10.7 0.1 0.74 8.6 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Rad9 PF04139.8 KPI41185.1 - 1.5e-59 201.2 0.0 1.8e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 KPI41185.1 - 5.2e-05 22.1 0.0 0.00029 19.7 0.0 2.3 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 zf-H2C2_2 PF13465.1 KPI41186.1 - 5.5e-06 26.4 4.0 5.5e-06 26.4 2.8 2.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KPI41186.1 - 2.1e-05 24.5 11.2 0.0099 16.1 0.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI41186.1 - 2.2e-05 24.4 11.6 0.0048 17.1 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger FAA_hydrolase PF01557.13 KPI41187.1 - 4e-43 147.4 0.0 5.3e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Epimerase PF01370.16 KPI41188.1 - 4.2e-59 199.8 0.0 5.9e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KPI41188.1 - 1.6e-31 109.3 0.0 8.5e-31 106.9 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KPI41188.1 - 6.9e-24 84.0 0.0 9.5e-24 83.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KPI41188.1 - 6.1e-23 81.0 0.2 3.5e-22 78.5 0.2 1.9 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KPI41188.1 - 3.7e-19 68.7 0.0 9.1e-19 67.4 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KPI41188.1 - 4.1e-09 36.7 0.0 1.3e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KPI41188.1 - 0.00012 21.9 0.2 0.0016 18.3 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase zf-RING_2 PF13639.1 KPI41189.1 - 8.4e-10 38.3 8.0 1.4e-09 37.6 5.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KPI41189.1 - 2.4e-07 30.7 4.7 5.1e-07 29.7 3.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KPI41189.1 - 9.3e-06 25.4 6.3 2.1e-05 24.2 4.4 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KPI41189.1 - 1.2e-05 25.2 5.1 2e-05 24.5 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI41189.1 - 2.2e-05 23.9 4.2 3.7e-05 23.2 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 KPI41189.1 - 3.1e-05 23.9 3.6 5.4e-05 23.1 2.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4_3 PF13920.1 KPI41189.1 - 0.00074 19.1 6.3 0.0012 18.4 4.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI41189.1 - 0.00099 18.7 6.4 0.0015 18.1 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.3 KPI41189.1 - 0.033 14.1 5.7 0.14 12.1 3.9 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KPI41189.1 - 0.059 12.9 3.7 0.1 12.2 2.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 KPI41189.1 - 1.7 8.7 5.4 3 7.9 3.7 1.4 1 0 0 1 1 1 0 RING-like domain PCI PF01399.22 KPI41190.1 - 0.00048 20.3 0.0 0.0017 18.6 0.0 2.0 2 0 0 2 2 2 1 PCI domain Lambda_Kil PF06301.6 KPI41190.1 - 0.12 11.8 0.1 0.37 10.2 0.1 1.9 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein zf-H2C2_2 PF13465.1 KPI41191.1 - 5.9e-08 32.6 9.5 9.8e-07 28.7 0.7 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KPI41191.1 - 1.4e-06 28.2 12.7 0.00056 20.0 2.8 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI41191.1 - 0.00017 21.7 14.6 0.0027 17.9 3.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 KPI41191.1 - 0.013 15.5 3.6 0.023 14.8 2.5 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KPI41191.1 - 0.075 13.2 3.1 6.6 7.0 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AMP-binding PF00501.23 KPI41192.1 - 1.3e-28 99.5 0.0 1.6e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Choline_kinase PF01633.15 KPI41193.1 - 3.2e-55 186.9 0.0 1.3e-54 184.9 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 KPI41193.1 - 2.7e-17 61.9 0.0 2.1e-16 59.0 0.0 2.3 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.18 KPI41193.1 - 3e-05 23.8 0.0 6.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Mur_ligase_M PF08245.7 KPI41194.1 - 1.7e-08 34.7 0.4 3.7e-08 33.6 0.3 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Nnf1 PF03980.9 KPI41194.1 - 0.099 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Nnf1 Cys_Met_Meta_PP PF01053.15 KPI41195.1 - 7.4e-59 198.9 0.0 2e-58 197.5 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KPI41195.1 - 0.00013 21.0 0.0 0.00022 20.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Phage_holin_3 PF05106.7 KPI41195.1 - 0.059 13.3 0.0 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) Aminotran_5 PF00266.14 KPI41195.1 - 0.093 11.4 0.0 0.18 10.4 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Abhydrolase_3 PF07859.8 KPI41197.1 - 6.6e-53 179.4 0.4 8.7e-53 179.0 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KPI41197.1 - 7.5e-08 31.5 0.0 1.7e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KPI41197.1 - 0.0023 17.7 0.1 0.0034 17.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KPI41197.1 - 0.0069 15.0 0.0 0.018 13.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) DUF2974 PF11187.3 KPI41197.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PhoPQ_related PF10142.4 KPI41197.1 - 0.035 12.5 0.0 5 5.4 0.0 2.1 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein Lipase_3 PF01764.20 KPI41197.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) zf-C3HC4_2 PF13923.1 KPI41199.1 - 0.00017 21.5 4.5 0.00033 20.5 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI41199.1 - 0.00025 20.6 3.8 0.00051 19.6 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI41199.1 - 0.0014 18.3 4.8 0.0024 17.5 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KPI41199.1 - 0.029 14.0 4.2 0.051 13.2 2.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KPI41199.1 - 0.046 13.4 0.7 0.49 10.1 0.8 2.5 2 1 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KPI41199.1 - 0.33 10.8 5.4 0.69 9.8 3.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KPI41199.1 - 0.35 10.7 5.1 0.67 9.8 3.5 1.5 1 0 0 1 1 1 0 Ring finger domain Pyrophosphatase PF00719.14 KPI41200.1 - 2.6e-34 117.9 0.1 3.4e-34 117.5 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase MFS_1 PF07690.11 KPI41201.1 - 2.8e-09 36.1 13.7 2.8e-09 36.1 9.5 2.3 2 1 1 3 3 3 1 Major Facilitator Superfamily UNC-93 PF05978.11 KPI41201.1 - 3.2e-07 29.9 2.2 3.2e-07 29.9 1.5 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Trp_dioxygenase PF03301.8 KPI41201.1 - 0.045 12.8 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase GST_C_3 PF14497.1 KPI41202.1 - 1.1e-05 25.7 0.0 3.6e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI41202.1 - 0.099 12.5 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain COesterase PF00135.23 KPI41203.1 - 1.4e-77 261.6 0.1 1.8e-77 261.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI41203.1 - 1.1e-05 25.0 0.3 0.00058 19.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI41203.1 - 0.054 12.7 0.2 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family GST_N_2 PF13409.1 KPI41204.1 - 6.6e-10 38.8 0.0 1.8e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KPI41204.1 - 6.7e-10 39.0 0.1 1.6e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KPI41204.1 - 1.2e-09 38.1 0.0 2.7e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain BTB_2 PF02214.17 KPI41204.1 - 8.2e-06 25.9 0.0 0.017 15.3 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain GST_C PF00043.20 KPI41204.1 - 0.035 14.0 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI41204.1 - 0.055 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KPI41204.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PBP1_TM PF14812.1 KPI41204.1 - 4.1 7.7 12.5 2.5 8.4 2.0 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PhyH PF05721.8 KPI41205.1 - 1.2e-18 67.8 0.1 1.7e-18 67.4 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Acyl-CoA_dh_1 PF00441.19 KPI41206.1 - 8.2e-41 139.5 6.8 8.2e-41 139.5 4.7 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KPI41206.1 - 2.7e-31 108.4 0.8 1.4e-30 106.1 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KPI41206.1 - 2.1e-18 65.5 0.9 4.4e-18 64.5 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KPI41206.1 - 4e-16 59.4 3.2 4e-16 59.4 2.2 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 KPI41206.1 - 0.015 15.6 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal HpaB_N PF11794.3 KPI41206.1 - 0.036 13.4 0.3 0.2 11.0 0.2 2.1 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal TTL PF03133.10 KPI41207.1 - 7.4e-58 195.7 0.0 1.3e-57 194.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 KPI41207.1 - 2.2e-31 108.7 0.0 3.7e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 KPI41207.1 - 0.00099 17.9 0.0 0.0027 16.5 0.0 1.7 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KPI41207.1 - 0.042 13.5 0.0 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain Calici_coat_C PF08435.6 KPI41207.1 - 0.056 12.7 0.1 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal Prefoldin_2 PF01920.15 KPI41208.1 - 4.2e-23 81.1 4.8 5.2e-23 80.8 3.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Spc24 PF08286.6 KPI41208.1 - 0.0018 17.9 6.1 0.44 10.2 1.7 2.2 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 ALIX_LYPXL_bnd PF13949.1 KPI41208.1 - 0.003 16.5 3.6 0.0042 16.0 2.5 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV FTA4 PF13093.1 KPI41208.1 - 0.011 15.1 3.7 0.015 14.7 2.6 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 PilJ PF13675.1 KPI41208.1 - 0.015 15.6 1.6 0.084 13.1 0.2 2.0 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Fib_alpha PF08702.5 KPI41208.1 - 0.016 15.2 3.4 0.021 14.9 2.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FlxA PF14282.1 KPI41208.1 - 0.037 13.9 4.0 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 FlxA-like protein DivIVA PF05103.8 KPI41208.1 - 0.046 13.7 7.9 0.16 12.0 5.3 1.9 1 1 0 1 1 1 0 DivIVA protein DivIC PF04977.10 KPI41208.1 - 0.061 12.8 8.8 1 8.9 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator Mnd1 PF03962.10 KPI41208.1 - 0.067 12.8 6.1 1.2 8.7 2.6 2.0 2 0 0 2 2 2 0 Mnd1 family Syntaxin-6_N PF09177.6 KPI41208.1 - 0.075 13.4 6.4 1.3 9.4 0.2 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF1465 PF07323.7 KPI41208.1 - 0.14 11.7 3.8 0.11 12.1 1.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Prefoldin PF02996.12 KPI41208.1 - 0.15 11.6 7.3 17 5.1 5.0 2.3 1 1 0 1 1 1 0 Prefoldin subunit V_ATPase_I PF01496.14 KPI41208.1 - 0.16 9.7 4.1 0.2 9.4 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 KPI41208.1 - 0.23 11.2 10.3 0.92 9.2 4.1 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CENP-Q PF13094.1 KPI41208.1 - 0.23 11.4 7.7 0.6 10.1 2.2 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Lzipper-MIP1 PF14389.1 KPI41208.1 - 0.25 11.4 8.8 1.9 8.6 6.1 2.2 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 THOC7 PF05615.8 KPI41208.1 - 0.33 11.2 5.9 7.2 6.8 1.4 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 IncA PF04156.9 KPI41208.1 - 0.45 10.0 12.9 1.8 8.0 8.9 1.7 1 1 0 1 1 1 0 IncA protein Adeno_PIX PF03955.9 KPI41208.1 - 0.46 11.0 4.9 4.3 7.9 0.2 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Rootletin PF15035.1 KPI41208.1 - 0.49 10.3 7.8 1.5 8.7 5.4 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion bZIP_1 PF00170.16 KPI41208.1 - 0.53 10.2 6.1 0.44 10.5 0.2 2.4 2 0 0 2 2 2 0 bZIP transcription factor Snf7 PF03357.16 KPI41208.1 - 0.53 9.6 0.0 0.53 9.6 0.0 2.7 2 1 1 3 3 3 0 Snf7 DUF4094 PF13334.1 KPI41208.1 - 0.79 10.1 3.5 2.9 8.3 1.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) TBPIP PF07106.8 KPI41208.1 - 0.86 9.1 9.1 2.5 7.6 0.3 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Rho_Binding PF08912.6 KPI41208.1 - 0.93 9.8 7.3 1.1 9.5 1.6 2.3 2 0 0 2 2 2 0 Rho Binding Cauli_AT PF03233.8 KPI41208.1 - 1 9.0 4.8 1.7 8.3 1.8 1.9 2 0 0 2 2 2 0 Aphid transmission protein DUF4618 PF15397.1 KPI41208.1 - 1.2 8.3 9.8 0.16 11.3 0.9 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) TMF_DNA_bd PF12329.3 KPI41208.1 - 1.4 8.7 13.9 1.2 8.9 0.4 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.1 KPI41208.1 - 2 8.9 8.9 3.6 8.0 0.2 2.3 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.3 KPI41208.1 - 2.1 8.2 10.2 3.2 7.6 3.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.9 KPI41208.1 - 2.9 7.4 11.5 25 4.4 8.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Cluap1 PF10234.4 KPI41208.1 - 3.4 6.7 9.6 18 4.4 6.6 1.8 1 1 0 1 1 1 0 Clusterin-associated protein-1 Ax_dynein_light PF10211.4 KPI41208.1 - 3.8 7.2 8.3 9.7 5.9 0.1 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain DUF972 PF06156.8 KPI41208.1 - 5.9 7.2 6.8 11 6.4 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF2205 PF10224.4 KPI41208.1 - 6.6 6.3 10.7 0.23 11.0 0.3 2.2 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF4200 PF13863.1 KPI41208.1 - 8.4 6.3 11.2 2.6 7.9 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) 7tm_7 PF08395.7 KPI41210.1 - 0.07 12.1 1.5 0.14 11.1 1.0 1.4 1 0 0 1 1 1 0 7tm Chemosensory receptor bZIP_1 PF00170.16 KPI41210.1 - 0.15 12.0 5.1 0.37 10.7 3.5 1.7 1 0 0 1 1 1 0 bZIP transcription factor Penicillinase_R PF03965.11 KPI41211.1 - 0.098 12.7 0.3 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 Penicillinase repressor DUF1546 PF07571.8 KPI41213.1 - 0.023 14.7 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) CaATP_NAI PF12515.3 KPI41214.1 - 0.0096 15.4 1.2 0.02 14.3 0.4 1.8 2 0 0 2 2 2 1 Ca2+-ATPase N terminal autoinhibitory domain DUF1126 PF06565.7 KPI41214.1 - 0.011 15.1 0.1 0.03 13.7 0.0 1.8 2 0 0 2 2 2 0 Repeat of unknown function (DUF1126) Asp PF00026.18 KPI41215.1 - 5.1e-54 183.6 1.2 7.4e-54 183.1 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KPI41215.1 - 3.8e-06 26.5 0.1 1.6e-05 24.5 0.1 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 KPI41215.1 - 0.0002 21.3 0.1 0.0044 16.9 0.0 3.1 2 2 0 3 3 3 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 KPI41215.1 - 0.059 13.1 0.9 0.68 9.7 0.1 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Nop14 PF04147.7 KPI41216.1 - 0.47 8.3 11.5 0.71 7.7 8.0 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KPI41216.1 - 1.2 7.1 6.8 1.7 6.5 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 KPI41216.1 - 2.4 7.1 7.2 3.4 6.6 5.0 1.3 1 0 0 1 1 1 0 BUD22 CFEM PF05730.6 KPI41217.1 - 1.1e-08 34.8 9.6 1.3e-08 34.4 6.7 1.1 1 0 0 1 1 1 1 CFEM domain Aldo_ket_red PF00248.16 KPI41218.1 - 5.8e-40 136.8 0.0 7.3e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DIE2_ALG10 PF04922.7 KPI41219.1 - 1.9e-74 251.0 15.3 1.9e-72 244.4 10.6 2.2 1 1 0 1 1 1 1 DIE2/ALG10 family Nramp PF01566.13 KPI41219.1 - 0.018 13.8 0.2 0.018 13.8 0.2 2.8 3 0 0 3 3 3 0 Natural resistance-associated macrophage protein Syntaxin-6_N PF09177.6 KPI41220.1 - 4.3e-23 81.5 0.4 1.4e-22 79.9 0.0 1.8 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 KPI41220.1 - 3.7e-13 48.9 2.3 3.7e-13 48.9 1.6 2.5 3 0 0 3 3 3 1 SNARE domain DUF4618 PF15397.1 KPI41220.1 - 0.19 11.0 2.5 0.21 10.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF2650 PF10853.3 KPI41220.1 - 1.7 8.1 4.3 2.8 7.4 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) PAT1 PF09770.4 KPI41221.1 - 8.9 4.4 15.6 11 4.1 10.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BTB PF00651.26 KPI41222.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.3 KPI41222.1 - 0.041 13.0 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) UBA_4 PF14555.1 KPI41222.1 - 0.096 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain Pkinase_Tyr PF07714.12 KPI41223.1 - 9.2e-11 41.2 0.0 1.5e-09 37.3 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KPI41223.1 - 9e-10 38.1 0.1 1.7e-07 30.7 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain DUF2985 PF11204.3 KPI41224.1 - 2.8e-28 97.4 2.4 5.8e-28 96.4 1.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) DUF3139 PF11337.3 KPI41224.1 - 0.046 14.0 0.6 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) DUF3605 PF12239.3 KPI41225.1 - 2.1e-51 173.9 6.1 2.6e-51 173.6 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Sec63 PF02889.11 KPI41227.1 - 2.7e-135 450.6 0.0 9.5e-95 317.4 0.3 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KPI41227.1 - 1e-54 184.5 0.1 2.3e-27 95.5 0.1 3.5 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 KPI41227.1 - 3.5e-16 59.5 0.0 1.5e-07 31.4 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KPI41227.1 - 5.5e-15 54.9 0.0 3.1e-06 26.9 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 KPI41227.1 - 1.3e-06 28.5 0.1 0.13 12.4 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KPI41227.1 - 5.6e-05 22.8 0.3 0.23 11.2 0.0 3.2 3 0 0 3 3 3 2 Part of AAA domain AAA PF00004.24 KPI41227.1 - 0.0012 19.0 0.1 1 9.5 0.0 3.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KPI41227.1 - 0.0024 17.3 0.1 7.3 5.9 0.0 3.7 4 0 0 4 4 4 2 IstB-like ATP binding protein PhoH PF02562.11 KPI41227.1 - 0.0033 16.6 0.0 0.079 12.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein DivIVA PF05103.8 KPI41228.1 - 0.39 10.7 0.0 0.39 10.7 0.0 3.3 2 1 1 3 3 3 0 DivIVA protein IncA PF04156.9 KPI41228.1 - 0.66 9.5 34.7 0.01 15.4 8.7 3.2 2 1 1 3 3 3 0 IncA protein Tropomyosin_1 PF12718.2 KPI41228.1 - 0.83 9.4 36.2 0.36 10.6 14.0 3.1 2 1 1 3 3 3 0 Tropomyosin like GAS PF13851.1 KPI41228.1 - 2.4 7.3 30.6 0.44 9.7 0.8 3.8 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.1 KPI41228.1 - 4.5 6.6 31.0 11 5.3 0.2 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TMPIT PF07851.8 KPI41228.1 - 5.1 6.0 7.4 12 4.8 5.2 1.7 1 0 0 1 1 1 0 TMPIT-like protein zf-CCHC PF00098.18 KPI41229.1 - 2.6e-45 150.2 61.8 1e-08 34.6 1.5 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 KPI41229.1 - 1.3e-10 40.7 44.9 0.025 14.2 0.6 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 KPI41229.1 - 3.5e-06 26.6 44.8 0.014 15.1 0.2 6.9 4 2 2 6 6 6 4 Zinc knuckle Caprin-1_C PF12287.3 KPI41229.1 - 0.65 9.3 3.7 0.78 9.0 2.6 1.3 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term ADH_zinc_N PF00107.21 KPI41230.1 - 1.2e-20 73.4 2.0 2.5e-20 72.3 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI41230.1 - 1.3e-09 37.7 3.3 1.1e-06 28.3 1.1 2.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 KPI41230.1 - 0.00071 18.7 0.1 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KPI41230.1 - 0.0032 17.0 0.1 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KPI41230.1 - 0.01 15.8 0.1 0.018 15.0 0.1 1.5 1 1 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 KPI41230.1 - 0.013 15.1 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 KPI41230.1 - 0.067 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KPI41230.1 - 0.097 13.1 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UCR_14kD PF02271.11 KPI41230.1 - 0.17 11.6 0.1 0.28 10.9 0.1 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit LRR_8 PF13855.1 KPI41232.1 - 0.023 14.4 0.6 1.6 8.5 0.3 3.7 4 1 0 4 4 4 0 Leucine rich repeat Adenosine_kin PF04008.9 KPI41232.1 - 0.077 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Adenosine specific kinase PDH PF02153.12 KPI41234.1 - 8.9e-13 47.7 0.0 1.2e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 KPI41234.1 - 5.4e-07 29.9 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KPI41234.1 - 2e-05 24.5 0.0 3.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KPI41234.1 - 0.00016 20.8 0.0 0.0003 20.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KPI41234.1 - 0.022 14.2 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KPI41234.1 - 0.023 14.3 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KPI41234.1 - 0.029 14.3 0.0 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Rossmann-like PF10727.4 KPI41234.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Rossmann-like domain Hydantoinase_B PF02538.9 KPI41235.1 - 1.9e-200 666.6 0.5 1.1e-195 650.9 0.0 2.1 2 0 0 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KPI41235.1 - 1.3e-96 323.0 0.2 4.1e-96 321.4 0.1 1.8 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KPI41235.1 - 2.3e-56 190.0 0.9 7.9e-55 185.0 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region FMN_dh PF01070.13 KPI41236.1 - 7.9e-101 337.4 1.0 6.1e-90 301.6 0.0 2.6 2 1 1 3 3 3 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KPI41236.1 - 1.1e-20 73.2 0.0 2e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KPI41236.1 - 0.00015 20.7 0.2 0.0012 17.8 0.0 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KPI41236.1 - 0.00047 19.1 0.0 0.00078 18.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 KPI41236.1 - 0.023 13.8 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Cytotoxic PF09000.5 KPI41236.1 - 0.048 13.6 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 Cytotoxic RCR PF12273.3 KPI41237.1 - 0.031 14.8 0.4 0.038 14.5 0.3 1.1 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red LON PF02190.11 KPI41238.1 - 1.9e-26 93.0 0.0 3.1e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain Abhydrolase_6 PF12697.2 KPI41238.1 - 2e-20 73.6 0.6 5.6e-20 72.1 0.0 2.1 2 0 0 2 2 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI41238.1 - 3.3e-15 56.1 0.1 5.9e-14 52.0 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 KPI41238.1 - 4e-11 42.6 0.0 9.4e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 KPI41238.1 - 7.9e-08 32.1 0.2 2.4e-07 30.5 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold zf-C3HC4_2 PF13923.1 KPI41238.1 - 1.5e-07 31.2 9.1 3.2e-07 30.2 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KPI41238.1 - 2.4e-07 30.4 10.2 4.6e-07 29.5 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KPI41238.1 - 4.4e-07 29.4 8.3 9e-07 28.4 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PGAP1 PF07819.8 KPI41238.1 - 7.8e-07 28.9 0.0 4.8e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein zf-C3HC4_3 PF13920.1 KPI41238.1 - 1.2e-06 28.1 8.1 2.2e-06 27.2 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI41238.1 - 7.4e-06 25.5 8.2 1.4e-05 24.7 5.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KPI41238.1 - 3e-05 23.8 8.3 6.3e-05 22.7 5.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING PTPlike_phytase PF14566.1 KPI41238.1 - 0.00015 21.8 0.0 0.0003 20.8 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate zf-RING_UBOX PF13445.1 KPI41238.1 - 0.00025 20.6 1.7 0.00025 20.6 1.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Y_phosphatase PF00102.22 KPI41238.1 - 0.00033 20.0 0.0 0.00063 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase zf-P11 PF03854.9 KPI41238.1 - 0.00034 20.0 4.9 0.00065 19.1 3.4 1.4 1 0 0 1 1 1 1 P-11 zinc finger zf-rbx1 PF12678.2 KPI41238.1 - 0.0021 18.1 3.0 0.0054 16.8 2.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger Lipase_3 PF01764.20 KPI41238.1 - 0.0034 16.9 0.5 0.0066 16.0 0.0 1.7 2 0 0 2 2 1 1 Lipase (class 3) PAF-AH_p_II PF03403.8 KPI41238.1 - 0.0047 15.2 0.7 0.32 9.2 0.0 2.2 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II zf-RING_4 PF14570.1 KPI41238.1 - 0.0072 15.8 6.5 0.019 14.5 4.5 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Ser_hydrolase PF06821.8 KPI41238.1 - 0.011 15.2 0.1 0.031 13.8 0.0 1.7 1 0 0 1 1 1 0 Serine hydrolase U-box PF04564.10 KPI41238.1 - 0.02 14.8 0.0 0.075 13.0 0.0 2.0 1 0 0 1 1 1 0 U-box domain Abhydrolase_3 PF07859.8 KPI41238.1 - 0.031 13.8 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 KPI41238.1 - 0.043 13.3 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF2305 PF10230.4 KPI41238.1 - 0.048 13.0 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 KPI41238.1 - 0.052 13.4 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 Putative lysophospholipase Prok-RING_4 PF14447.1 KPI41238.1 - 0.095 12.2 4.2 0.25 10.9 2.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 BAAT_C PF08840.6 KPI41238.1 - 0.11 12.1 0.0 0.47 10.1 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal zf-Nse PF11789.3 KPI41238.1 - 0.12 11.8 3.3 0.27 10.8 2.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Y_phosphatase3 PF13350.1 KPI41238.1 - 0.15 12.2 0.0 0.45 10.7 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF1272 PF06906.6 KPI41238.1 - 0.29 10.9 3.9 0.65 9.8 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.1 KPI41238.1 - 0.41 10.4 5.0 0.98 9.2 3.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein F-box-like PF12937.2 KPI41239.1 - 0.0016 18.1 0.6 0.01 15.5 0.0 2.7 3 0 0 3 3 3 1 F-box-like LRR_8 PF13855.1 KPI41239.1 - 0.02 14.6 12.5 4.8 7.0 1.0 5.6 4 1 1 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 KPI41239.1 - 0.034 13.7 15.2 4.4 7.0 0.0 6.5 6 1 2 8 8 8 0 Leucine Rich repeats (2 copies) EndoU_bacteria PF14436.1 KPI41240.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial EndoU nuclease Hexokinase_2 PF03727.11 KPI41241.1 - 1.5e-22 79.9 0.0 2.4e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KPI41241.1 - 6.7e-16 58.2 0.0 1.3e-15 57.3 0.0 1.5 1 1 0 1 1 1 1 Hexokinase HSP70 PF00012.15 KPI41242.1 - 1.8e-227 756.0 3.9 2e-227 755.8 2.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KPI41242.1 - 4.6e-16 58.3 0.0 7.1e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.11 KPI41242.1 - 0.0022 17.6 0.0 0.0044 16.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KPI41242.1 - 0.0025 16.9 0.1 0.036 13.1 0.0 2.2 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase Oxysterol_BP PF01237.13 KPI41243.1 - 4.8e-132 439.7 0.0 1.4e-131 438.2 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.1 KPI41243.1 - 2e-17 62.7 0.4 1.2e-11 44.4 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KPI41243.1 - 2.4e-16 59.8 0.0 8.4e-11 42.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KPI41243.1 - 9.4e-16 56.7 0.1 6.5e-05 22.5 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KPI41243.1 - 6.5e-12 44.4 0.0 0.0019 18.2 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KPI41243.1 - 9.8e-12 45.0 0.0 4.1e-05 23.9 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.24 KPI41243.1 - 3.1e-10 40.2 0.2 6.4e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KPI41243.1 - 8.3e-09 35.6 1.0 3.2e-08 33.7 0.7 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KPI41243.1 - 3.7e-06 26.9 0.9 9.1e-06 25.6 0.6 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain adh_short PF00106.20 KPI41244.1 - 3.2e-26 92.2 1.5 5e-26 91.5 1.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI41244.1 - 4.3e-13 49.5 0.0 6.2e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI41244.1 - 2.7e-11 43.4 0.3 3.7e-11 43.0 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KPI41244.1 - 0.0013 17.7 0.2 0.0018 17.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KPI41244.1 - 0.0045 16.7 2.1 0.012 15.3 0.3 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KPI41244.1 - 0.0052 16.8 1.2 0.064 13.2 0.9 2.1 1 1 0 1 1 1 1 NADH(P)-binding UQ_con PF00179.21 KPI41245.1 - 3.7e-09 36.1 0.0 6.4e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KPI41245.1 - 0.19 11.6 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain Sugar_tr PF00083.19 KPI41247.1 - 1.7e-74 251.0 19.3 2e-74 250.8 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI41247.1 - 2.2e-24 85.8 30.4 5e-17 61.6 7.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gly_transf_sug PF04488.10 KPI41249.1 - 3.5e-10 40.1 0.0 8.2e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KPI41249.1 - 0.012 14.8 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein YopR_core PF09025.5 KPI41249.1 - 0.17 11.9 0.0 7.9 6.4 0.0 2.3 2 0 0 2 2 2 0 YopR Core Uricase PF01014.13 KPI41250.1 - 3.6e-66 221.4 3.4 2.8e-36 124.6 0.0 2.3 2 1 0 2 2 2 2 Uricase PAP2 PF01569.16 KPI41251.1 - 2.2e-21 75.8 6.3 5e-21 74.7 4.4 1.6 1 0 0 1 1 1 1 PAP2 superfamily Kelch_4 PF13418.1 KPI41252.1 - 1.5e-06 27.8 7.0 0.023 14.4 0.3 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Spore_YtfJ PF09579.5 KPI41252.1 - 2.3 8.1 5.3 18 5.2 3.7 2.3 1 1 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) FMO-like PF00743.14 KPI41254.1 - 5.8e-49 166.6 0.0 1.1e-48 165.7 0.0 1.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KPI41254.1 - 6.1e-21 75.4 0.0 9.4e-20 71.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI41254.1 - 1.7e-07 31.3 0.0 3.1e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI41254.1 - 3.2e-06 27.0 0.1 0.038 13.7 0.2 3.0 2 1 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 KPI41254.1 - 0.0028 16.6 0.2 0.024 13.5 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KPI41254.1 - 0.0063 16.5 0.1 0.017 15.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI41254.1 - 0.025 13.4 0.1 3.2 6.5 0.0 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase Lipase_3 PF01764.20 KPI41255.1 - 3.2e-05 23.5 0.0 7.8e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KPI41255.1 - 0.0079 15.9 0.0 0.024 14.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KPI41255.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.7 KPI41255.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) p450 PF00067.17 KPI41256.1 - 1.1e-30 106.6 0.0 1.3e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Allantoicase PF03561.10 KPI41258.1 - 2.2e-91 303.1 2.6 3.1e-50 169.5 0.1 2.1 2 0 0 2 2 2 2 Allantoicase repeat Methyltransf_11 PF08241.7 KPI41259.1 - 2.6e-10 40.6 0.0 4.5e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI41259.1 - 1.7e-08 34.7 0.0 2.7e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI41259.1 - 3.1e-07 29.7 0.0 4.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KPI41259.1 - 8.6e-06 25.4 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI41259.1 - 0.00014 22.3 0.0 0.0003 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI41259.1 - 0.00056 19.9 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI41259.1 - 0.00086 19.7 0.0 0.0018 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI41259.1 - 0.00091 18.9 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF3950 PF13132.1 KPI41259.1 - 0.0063 16.0 0.3 0.014 14.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3950) BNR_3 PF13859.1 KPI41259.1 - 0.025 13.6 0.1 0.035 13.1 0.1 1.2 1 0 0 1 1 1 0 BNR repeat-like domain Tannase PF07519.6 KPI41260.1 - 6.6e-19 67.9 0.0 7.7e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase RibD_C PF01872.12 KPI41261.1 - 1.1e-09 38.1 0.0 1.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain F-box-like PF12937.2 KPI41261.1 - 0.0011 18.5 0.3 0.003 17.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like Cep57_MT_bd PF06657.8 KPI41261.1 - 0.013 15.4 0.3 0.031 14.2 0.2 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Glyco_transf_28 PF03033.15 KPI41262.1 - 2.7e-18 66.0 0.0 1.5e-17 63.6 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KPI41262.1 - 3.6e-06 25.8 0.0 5.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KPI41262.1 - 0.00023 20.8 1.3 0.0052 16.4 0.0 2.7 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 KPI41262.1 - 0.04 14.0 0.0 0.16 12.1 0.0 2.1 1 1 0 1 1 1 0 ATG C terminal domain UIM PF02809.15 KPI41262.1 - 4.9 6.9 22.9 11 5.9 0.0 6.3 6 0 0 6 6 6 0 Ubiquitin interaction motif YlqD PF11068.3 KPI41262.1 - 5.3 7.0 15.6 0.32 11.0 6.1 2.5 2 0 0 2 2 2 0 YlqD protein DNA_binding_1 PF01035.15 KPI41264.1 - 4.3e-20 71.2 0.6 8e-20 70.3 0.4 1.4 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain BTB PF00651.26 KPI41265.1 - 0.00016 21.6 0.0 0.00037 20.4 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.11 KPI41266.1 - 5.6e-11 41.7 14.2 5.6e-11 41.7 9.8 3.8 2 2 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI41267.1 - 8.5e-92 308.0 18.9 1.8e-86 290.5 6.6 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI41267.1 - 1.2e-12 47.2 52.3 2.1e-09 36.5 15.3 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily HEAT_2 PF13646.1 KPI41268.1 - 4e-06 27.0 8.6 0.00017 21.8 0.2 5.3 5 1 2 7 7 6 1 HEAT repeats HEAT PF02985.17 KPI41268.1 - 1.8e-05 24.3 6.8 0.0063 16.4 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 KPI41268.1 - 0.00031 21.1 6.5 0.0016 18.8 0.4 4.1 4 0 0 4 4 4 1 HEAT-like repeat TAFH PF07531.9 KPI41268.1 - 0.09 12.4 0.0 9.5 5.9 0.0 2.8 2 0 0 2 2 2 0 NHR1 homology to TAF Fungal_trans_2 PF11951.3 KPI41269.1 - 0.0016 17.1 2.0 0.0027 16.3 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_38 PF01074.17 KPI41270.1 - 5.6e-90 301.3 1.8 1e-89 300.4 1.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KPI41270.1 - 2.9e-72 243.9 0.0 4.9e-72 243.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KPI41270.1 - 1.4e-26 92.4 0.1 2.9e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_28 PF00295.12 KPI41272.1 - 1.4e-46 158.9 3.0 3.6e-46 157.6 2.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Fungal_trans PF04082.13 KPI41273.1 - 1.5e-50 171.4 0.3 2.7e-50 170.6 0.2 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain DEAD PF00270.24 KPI41274.1 - 1.2e-06 28.0 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase NACHT PF05729.7 KPI41274.1 - 0.00069 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain T2SE PF00437.15 KPI41274.1 - 0.0063 15.4 0.0 0.024 13.5 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KPI41274.1 - 0.013 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.1 KPI41274.1 - 0.018 14.8 0.1 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 KPI41274.1 - 0.09 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KPI41274.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 KPI41274.1 - 0.15 12.1 0.0 0.41 10.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_membrane_2 PF06472.10 KPI41275.1 - 5.5e-107 357.0 1.1 9.6e-107 356.2 0.8 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KPI41275.1 - 9.9e-18 64.7 0.0 2.5e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KPI41275.1 - 3e-05 24.1 0.0 7.2e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KPI41275.1 - 0.0063 15.5 0.0 0.17 10.9 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 KPI41275.1 - 0.0085 15.6 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KPI41275.1 - 0.01 16.1 2.5 0.015 15.6 0.2 2.5 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.14 KPI41275.1 - 0.016 14.4 0.2 0.076 12.2 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KPI41275.1 - 0.02 14.8 0.1 0.18 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 KPI41275.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TGT PF01702.13 KPI41277.1 - 1.5e-84 283.0 0.1 3.8e-51 173.6 0.0 2.1 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase Bac_surface_Ag PF01103.18 KPI41278.1 - 1.3e-26 93.8 0.3 2.2e-26 93.0 0.2 1.3 1 0 0 1 1 1 1 Surface antigen TIP41 PF04176.8 KPI41279.1 - 6.3e-73 243.9 0.1 8.3e-73 243.5 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family Ctr PF04145.10 KPI41280.1 - 3e-20 72.7 0.3 3.5e-20 72.5 0.2 1.0 1 0 0 1 1 1 1 Ctr copper transporter family MFS_1 PF07690.11 KPI41281.1 - 7e-33 113.7 42.5 1.9e-30 105.8 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.17 KPI41282.1 - 2.8e-155 517.1 0.1 3.2e-155 516.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KPI41282.1 - 0.0009 18.0 0.0 0.003 16.3 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KPI41282.1 - 0.086 12.0 0.0 0.89 8.7 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Glyco_hydro_3 PF00933.16 KPI41283.1 - 3.1e-71 239.8 0.0 4.8e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KPI41283.1 - 5.7e-63 212.4 0.0 1.7e-62 210.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KPI41283.1 - 7.3e-26 89.9 0.4 1.7e-25 88.7 0.3 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KPI41283.1 - 3.3e-14 52.7 0.1 6.8e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 PA14 domain Yip1 PF04893.12 KPI41283.1 - 4.6e-05 22.9 5.5 0.0056 16.1 0.8 2.2 2 0 0 2 2 2 2 Yip1 domain Oxidored_q3 PF00499.15 KPI41283.1 - 0.0045 16.7 2.0 0.0079 15.9 1.4 1.3 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Pro_isomerase PF00160.16 KPI41284.1 - 9.3e-31 107.1 0.0 1.5e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KPI41284.1 - 6.3e-16 57.7 0.1 1.3e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI41284.1 - 3.2e-12 46.2 0.0 6.8e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI41284.1 - 9.4e-11 41.3 0.1 2.7e-10 39.9 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KPI41284.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ribosomal_L19 PF01245.15 KPI41286.1 - 8.7e-17 60.9 0.2 1.8e-16 59.8 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L19 bZIP_2 PF07716.10 KPI41287.1 - 1.5 8.7 7.5 2.6 7.9 2.5 2.8 2 0 0 2 2 2 0 Basic region leucine zipper PRP4 PF08799.6 KPI41288.1 - 1e-06 27.9 4.5 1.9e-06 27.0 0.0 3.0 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Prp18 PF02840.10 KPI41288.1 - 0.00013 21.7 0.4 0.00048 19.9 0.0 2.0 2 0 0 2 2 2 1 Prp18 domain MFS_1 PF07690.11 KPI41289.1 - 7e-36 123.6 25.0 1.1e-35 123.0 17.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Jiraiya PF15038.1 KPI41289.1 - 0.24 10.7 4.7 0.052 12.9 0.4 1.9 2 0 0 2 2 2 0 Jiraiya Synapsin_N PF10581.4 KPI41290.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.8 1 0 0 1 1 1 0 Synapsin N-terminal Attacin_N PF03768.10 KPI41290.1 - 1.5 8.7 4.8 4.4 7.2 0.1 3.1 3 0 0 3 3 3 0 Attacin, N-terminal region MFS_1 PF07690.11 KPI41291.1 - 3e-43 147.9 39.6 3e-43 147.9 27.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI41291.1 - 2.1e-17 62.8 15.0 6.9e-16 57.8 1.2 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 KPI41291.1 - 0.00014 20.0 5.8 0.00014 20.0 4.0 2.3 2 1 0 2 2 2 1 Transmembrane secretion effector Zip PF02535.17 KPI41291.1 - 0.4 9.6 6.2 0.85 8.5 1.0 2.6 2 0 0 2 2 2 0 ZIP Zinc transporter Isochorismatase PF00857.15 KPI41292.1 - 2.9e-22 79.4 0.0 4.2e-22 78.8 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family Acetyltransf_1 PF00583.19 KPI41293.1 - 1.5e-07 31.3 0.3 5.7e-07 29.4 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI41293.1 - 5e-06 26.5 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI41293.1 - 8.9e-06 25.8 0.0 1.7e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KPI41293.1 - 0.0022 17.7 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein DUF928 PF06051.7 KPI41293.1 - 0.036 13.6 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) Tubulin_3 PF14881.1 KPI41294.1 - 2.2e-77 258.6 0.1 3.9e-77 257.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 KPI41294.1 - 3.9e-38 130.0 0.0 8.3e-38 128.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 KPI41294.1 - 6e-06 26.2 0.0 0.0014 18.5 0.0 2.5 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain DUF1446 PF07287.6 KPI41295.1 - 3.6e-117 390.8 0.1 4.3e-117 390.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) LYTB PF02401.13 KPI41295.1 - 0.063 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 LytB protein ABC2_membrane PF01061.19 KPI41296.1 - 3.3e-84 281.2 50.4 4.1e-44 150.2 14.0 3.1 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 KPI41296.1 - 8.3e-38 129.7 0.0 4e-18 66.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KPI41296.1 - 1.7e-34 117.5 1.3 6.6e-27 93.1 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KPI41296.1 - 2e-18 66.2 0.0 5.4e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KPI41296.1 - 7.8e-08 31.9 0.1 8.7e-06 25.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 KPI41296.1 - 1.5e-07 30.7 49.4 2.9e-05 23.2 18.8 3.2 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 KPI41296.1 - 2.5e-06 27.4 0.1 0.0033 17.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KPI41296.1 - 2e-05 23.8 0.0 0.0013 17.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 KPI41296.1 - 3.1e-05 23.4 2.0 0.0019 17.6 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KPI41296.1 - 0.00054 19.9 0.4 0.0039 17.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KPI41296.1 - 0.0031 17.6 0.4 0.64 10.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KPI41296.1 - 0.0072 15.8 2.2 0.037 13.5 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KPI41296.1 - 0.0076 16.5 0.4 0.076 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KPI41296.1 - 0.009 16.8 0.0 0.12 13.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KPI41296.1 - 0.013 15.1 2.1 2.2 7.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 KPI41296.1 - 0.021 15.3 0.1 7.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 KPI41296.1 - 0.023 14.3 2.2 2.2 7.9 0.2 2.7 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.14 KPI41296.1 - 0.13 11.4 0.0 2.2 7.4 0.0 2.7 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.1 KPI41296.1 - 0.14 11.6 0.1 2 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain GvpD PF07088.6 KPI41296.1 - 0.19 9.9 0.2 5 5.3 0.0 2.1 2 0 0 2 2 2 0 GvpD gas vesicle protein AAA_19 PF13245.1 KPI41296.1 - 0.44 10.3 3.2 7.6 6.3 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 KPI41296.1 - 1.2 8.6 3.2 7.7 6.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.2 KPI41297.1 - 7.7e-19 68.4 0.0 9.7e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI41297.1 - 6.5e-10 38.9 0.1 9e-10 38.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KPI41297.1 - 6.8e-05 22.6 0.1 0.00028 20.6 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Thioesterase PF00975.15 KPI41297.1 - 0.00018 21.8 0.0 0.00054 20.2 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 KPI41297.1 - 0.0055 16.2 0.1 0.0086 15.6 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KPI41297.1 - 0.036 13.6 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.6 KPI41297.1 - 0.04 13.3 0.0 0.088 12.2 0.0 1.5 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_2 PF02230.11 KPI41297.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KPI41297.1 - 0.086 12.0 0.1 0.7 9.0 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family PDEase_II PF02112.10 KPI41298.1 - 5.1e-51 173.5 0.0 2.7e-23 82.4 0.0 3.1 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 KPI41298.1 - 0.00038 20.0 0.1 0.0011 18.5 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KPI41298.1 - 0.072 12.7 0.6 0.18 11.4 0.4 1.8 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily DnaJ PF00226.26 KPI41299.1 - 4.2e-22 77.6 3.3 4.2e-22 77.6 2.3 2.8 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 KPI41299.1 - 3.4e-17 61.8 9.6 5.1e-07 29.2 0.0 5.0 4 2 1 5 5 4 4 TPR repeat TPR_1 PF00515.23 KPI41299.1 - 5.4e-17 60.5 7.8 0.0033 16.9 0.0 7.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 KPI41299.1 - 1.8e-14 52.3 2.1 0.39 10.6 0.0 7.8 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 KPI41299.1 - 7.4e-14 50.4 14.3 0.044 13.7 0.0 8.3 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 KPI41299.1 - 1.2e-11 44.9 17.0 7.7e-05 23.2 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KPI41299.1 - 1.3e-10 40.9 9.2 0.065 13.9 0.4 6.8 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 KPI41299.1 - 2.7e-08 33.5 7.4 0.011 15.6 0.3 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KPI41299.1 - 4.1e-08 33.4 17.1 1.3e-05 25.4 1.6 5.5 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KPI41299.1 - 0.00042 20.5 9.9 8.4 7.0 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 KPI41299.1 - 0.0019 18.2 16.0 0.0082 16.2 1.9 4.2 4 1 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KPI41299.1 - 0.0078 16.1 10.4 2.6 8.0 0.8 4.9 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KPI41299.1 - 0.015 15.0 6.5 12 5.9 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 KPI41299.1 - 0.22 11.8 0.0 0.22 11.8 0.0 4.4 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF1895 PF08988.5 KPI41299.1 - 3.5 7.7 8.4 16 5.6 0.6 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1895) Cupin_1 PF00190.17 KPI41300.1 - 6.2e-31 106.7 0.0 3.2e-14 52.5 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KPI41300.1 - 3e-24 84.2 0.8 4.2e-12 45.3 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KPI41300.1 - 7.9e-10 37.9 0.0 0.0012 18.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KPI41300.1 - 1.3e-07 31.3 0.1 0.0002 21.0 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 KPI41300.1 - 2e-05 24.3 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 2 Cupin MannoseP_isomer PF01050.13 KPI41300.1 - 9.6e-05 22.0 0.0 0.065 12.8 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase ARD PF03079.9 KPI41300.1 - 0.0001 22.3 0.4 0.019 14.8 0.1 2.2 2 0 0 2 2 2 1 ARD/ARD' family CENP-C_C PF11699.3 KPI41300.1 - 0.017 15.0 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Mif2/CENP-C like 3-HAO PF06052.7 KPI41300.1 - 0.019 14.3 0.0 0.71 9.2 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase GPI PF06560.6 KPI41300.1 - 0.16 11.0 0.0 0.32 9.9 0.0 1.5 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) adh_short PF00106.20 KPI41301.1 - 4.4e-13 49.4 0.5 6e-13 49.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI41301.1 - 1.6e-06 27.8 0.1 2.2e-06 27.4 0.1 1.3 1 1 0 1 1 1 1 KR domain Nucleopor_Nup85 PF07575.8 KPI41302.1 - 2.5e-19 68.9 5.5 1.8e-10 39.6 1.1 3.8 3 1 0 3 3 3 3 Nup85 Nucleoporin IBN_N PF03810.14 KPI41303.1 - 8.2e-12 44.8 3.4 2e-11 43.6 0.2 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KPI41303.1 - 6e-07 29.4 0.3 1.5e-06 28.2 0.2 1.6 1 0 0 1 1 1 1 Exportin 1-like protein Seipin PF06775.9 KPI41304.1 - 2e-47 161.2 0.0 6.4e-47 159.6 0.0 1.7 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) ER_lumen_recept PF00810.13 KPI41304.1 - 6.9e-36 123.9 8.3 6.9e-36 123.9 5.8 2.5 3 0 0 3 3 3 1 ER lumen protein retaining receptor Fijivirus_P9-2 PF06837.6 KPI41304.1 - 0.01 14.9 3.9 0.025 13.7 0.1 2.3 2 0 0 2 2 2 0 Fijivirus P9-2 protein AGTRAP PF06396.6 KPI41304.1 - 1.6 8.4 9.6 1.2 8.7 0.0 2.9 3 0 0 3 3 3 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Acetyltransf_3 PF13302.1 KPI41305.1 - 7.3e-07 29.4 0.0 1.5e-06 28.4 0.0 1.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KPI41305.1 - 0.035 13.9 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_42 PF02449.10 KPI41306.1 - 0.027 13.5 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 Beta-galactosidase O-antigen_lig PF13425.1 KPI41306.1 - 0.038 13.9 0.2 0.048 13.6 0.1 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein F-box PF00646.28 KPI41307.1 - 0.035 13.7 0.2 0.1 12.2 0.1 1.8 1 0 0 1 1 1 0 F-box domain DUF972 PF06156.8 KPI41308.1 - 6.1 7.2 8.0 3.7 7.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) GIT_SHD PF08518.6 KPI41309.1 - 5.2e-18 64.0 7.4 2.5e-13 49.1 0.5 3.1 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT Syntaxin PF00804.20 KPI41309.1 - 0.0008 19.5 1.1 0.0008 19.5 0.8 4.6 3 2 2 5 5 5 1 Syntaxin PM0188 PF11477.3 KPI41309.1 - 0.024 13.4 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 Sialyltransferase PMO188 V_ATPase_I PF01496.14 KPI41309.1 - 0.17 9.7 15.7 0.16 9.8 0.2 2.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Brr6_like_C_C PF10104.4 KPI41310.1 - 1e-39 135.1 2.0 1.4e-39 134.7 1.4 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain NADHdh_A3 PF14987.1 KPI41310.1 - 0.2 11.6 1.5 0.48 10.3 1.0 1.6 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 UQ_con PF00179.21 KPI41311.1 - 5e-06 25.9 0.0 7.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Gag_p12 PF01141.13 KPI41311.1 - 0.45 10.6 3.2 2.4 8.3 0.0 2.4 2 1 0 2 2 2 0 Gag polyprotein, inner coat protein p12 AAA PF00004.24 KPI41312.1 - 4.1e-17 62.6 0.0 1.2e-16 61.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KPI41312.1 - 0.06 13.0 0.5 0.14 11.8 0.4 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 KPI41312.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SYS1 PF09801.4 KPI41313.1 - 5.2e-36 123.8 4.9 7.9e-36 123.2 3.4 1.2 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF485 PF04341.7 KPI41313.1 - 0.022 14.4 2.4 0.022 14.4 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF485 PDCD2_C PF04194.8 KPI41314.1 - 2.3e-48 163.8 0.1 6.9e-48 162.3 0.0 1.7 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Polysacc_deac_1 PF01522.16 KPI41315.1 - 1.6e-13 50.3 0.0 2.7e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 KPI41315.1 - 0.00014 21.3 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Amino_oxidase PF01593.19 KPI41316.1 - 9.1e-49 166.7 0.2 1.9e-43 149.1 0.1 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Tautomerase PF01361.16 KPI41317.1 - 1.5e-07 30.9 0.0 3.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.1 KPI41317.1 - 0.0017 18.3 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Tautomerase enzyme DUF917 PF06032.7 KPI41319.1 - 1.5e-73 247.3 0.0 8.7e-48 162.6 0.0 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 KPI41319.1 - 7.8e-47 159.7 8.2 1.5e-42 145.7 3.7 3.4 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KPI41319.1 - 4.6e-35 120.6 0.7 5.3e-31 107.4 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 KPI41319.1 - 3.4e-06 25.6 1.8 0.0018 16.6 0.0 2.3 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 KPI41319.1 - 0.006 15.9 0.2 0.006 15.9 0.1 2.2 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.1 KPI41319.1 - 0.014 15.2 2.3 0.28 11.0 0.0 3.0 3 0 0 3 3 3 0 Cell division protein FtsA StbA PF06406.6 KPI41319.1 - 0.027 13.4 0.8 1 8.2 0.1 2.7 2 0 0 2 2 2 0 StbA protein RTA1 PF04479.8 KPI41321.1 - 7.4e-37 127.0 14.1 7.4e-37 127.0 9.8 1.4 1 1 0 1 1 1 1 RTA1 like protein UPF0220 PF05255.6 KPI41321.1 - 0.044 13.0 5.6 0.09 12.0 3.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) Abhydrolase_6 PF12697.2 KPI41322.1 - 0.00014 21.8 0.0 0.00032 20.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI41322.1 - 0.0057 16.2 0.0 0.027 14.0 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold LCAT PF02450.10 KPI41322.1 - 0.0064 15.5 0.6 0.028 13.3 0.0 2.1 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 KPI41322.1 - 0.022 14.0 0.1 0.17 11.1 0.0 2.3 3 0 0 3 3 3 0 Putative serine esterase (DUF676) NAD_binding_10 PF13460.1 KPI41323.1 - 0.074 13.0 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding ETS_PEA3_N PF04621.8 KPI41324.1 - 2 7.5 19.6 3.7 6.6 12.1 2.0 1 1 1 2 2 2 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Metallophos PF00149.23 KPI41325.1 - 3e-05 23.4 1.3 6.1e-05 22.4 0.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 KPI41325.1 - 0.0002 21.3 0.0 0.0051 16.8 0.0 2.8 1 1 1 2 2 2 1 5'-nucleotidase, C-terminal domain AhpC-TSA PF00578.16 KPI41326.1 - 6.2e-27 93.7 0.0 8.2e-27 93.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KPI41326.1 - 1.8e-20 72.9 0.0 1.6e-19 69.9 0.0 1.9 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 KPI41326.1 - 8.9e-05 22.5 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like DUF899 PF05988.7 KPI41326.1 - 0.0009 18.7 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA_2 PF13911.1 KPI41326.1 - 0.0033 17.3 0.0 0.0058 16.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Thioredoxin_7 PF13899.1 KPI41326.1 - 0.042 13.8 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.1 KPI41326.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain XPG_I PF00867.13 KPI41327.1 - 2.5e-21 75.5 0.1 5.6e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KPI41327.1 - 2.2e-06 27.8 0.0 5.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 KPI41327.1 - 0.0011 18.4 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing DUF374 PF04028.8 KPI41327.1 - 0.13 11.4 0.1 0.64 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF374) NifU_N PF01592.11 KPI41328.1 - 1.2e-53 180.4 0.1 1.7e-53 179.9 0.1 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain DUF1858 PF08984.6 KPI41328.1 - 0.14 11.8 0.2 0.84 9.3 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1858) AMP-binding PF00501.23 KPI41329.1 - 2.1e-32 112.0 0.0 2.5e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI41329.1 - 2.3e-09 38.0 0.0 3.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribonuc_red_lgC PF02867.10 KPI41330.1 - 4.2e-219 728.5 0.0 6.4e-219 727.9 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KPI41330.1 - 6.1e-23 80.4 0.0 1.5e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KPI41330.1 - 5.6e-17 61.9 0.0 1.4e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain Nodulin_late PF07127.6 KPI41331.1 - 0.012 15.7 8.5 0.4 10.8 0.1 3.2 3 0 0 3 3 3 0 Late nodulin protein Gamma-thionin PF00304.15 KPI41331.1 - 5.5 7.0 35.0 3.6 7.6 4.1 3.4 3 0 0 3 3 3 0 Gamma-thionin family TFIIA PF03153.8 KPI41332.1 - 1e-58 200.0 4.7 1.2e-58 199.7 3.3 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 KPI41332.1 - 0.14 10.0 3.3 0.17 9.7 2.3 1.2 1 0 0 1 1 1 0 Nop14-like family MbeD_MobD PF04899.7 KPI41332.1 - 0.16 11.8 1.6 7 6.6 0.0 2.6 2 0 0 2 2 2 0 MbeD/MobD like RCC1 PF00415.13 KPI41333.1 - 9.5e-32 108.9 14.3 1.2e-08 35.0 0.0 7.5 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KPI41333.1 - 1.9e-24 84.6 27.9 3.3e-08 32.9 0.2 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Nucleoporin_N PF08801.6 KPI41333.1 - 0.014 14.1 0.1 2.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like ENOD93 PF03386.9 KPI41333.1 - 0.043 13.5 0.0 0.086 12.5 0.0 1.5 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein Acetyltransf_1 PF00583.19 KPI41334.1 - 1.5e-05 24.8 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI41334.1 - 0.00015 21.8 0.0 0.0002 21.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TPT PF03151.11 KPI41335.1 - 6.8e-15 55.0 11.4 6.8e-15 55.0 7.9 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KPI41335.1 - 3.4e-05 23.8 11.6 3.4e-05 23.8 8.1 2.8 2 1 1 3 3 3 1 EamA-like transporter family TRI9 PF08195.6 KPI41335.1 - 0.15 11.7 0.5 0.52 9.9 0.2 2.0 2 0 0 2 2 2 0 TRI9 protein DUF4293 PF14126.1 KPI41335.1 - 2.3 8.1 10.8 4.5 7.1 0.3 3.7 1 1 2 4 4 4 0 Domain of unknown function (DUF4293) Transpep_BrtH PF14399.1 KPI41337.1 - 0.28 10.4 0.0 0.5 9.5 0.0 1.3 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase CHZ PF09649.5 KPI41338.1 - 6.1e-13 47.7 5.2 6.1e-13 47.7 3.6 2.7 3 1 0 3 3 3 1 Histone chaperone domain CHZ Spc42p PF11544.3 KPI41338.1 - 0.042 13.7 1.0 0.063 13.2 0.1 1.6 1 1 1 2 2 2 0 Spindle pole body component Spc42p CDC27 PF09507.5 KPI41338.1 - 4.8 6.2 20.0 5.2 6.1 13.9 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 GET2 PF08690.5 KPI41338.1 - 7.6 5.6 6.2 8.4 5.5 4.3 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DIOX_N PF14226.1 KPI41339.1 - 2e-17 63.7 0.0 4e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI41339.1 - 4.1e-13 49.4 0.0 6.5e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_7 PF03441.9 KPI41340.1 - 2.5e-75 253.2 1.7 3.8e-75 252.6 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KPI41340.1 - 1.1e-38 132.5 0.2 3e-38 131.1 0.0 1.8 2 0 0 2 2 2 1 DNA photolyase Ribosomal_S9 PF00380.14 KPI41343.1 - 1.4e-39 135.0 0.6 1.6e-39 134.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 KPI41343.1 - 0.022 12.2 0.0 0.024 12.1 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Peptidase_S10 PF00450.17 KPI41344.1 - 1.8e-75 254.6 0.9 2.5e-75 254.1 0.6 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase HET PF06985.6 KPI41346.1 - 3.8e-21 75.7 1.8 7.1e-21 74.8 1.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3024 PF11225.3 KPI41348.1 - 0.09 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) Rick_17kDa_Anti PF05433.10 KPI41348.1 - 0.65 9.6 7.3 1.2 8.8 0.4 2.7 3 0 0 3 3 3 0 Glycine zipper 2TM domain Glyco_hydro_76 PF03663.9 KPI41350.1 - 1.4e-23 83.8 6.6 1.6e-17 63.9 0.3 3.4 2 1 1 3 3 3 2 Glycosyl hydrolase family 76 Fungal_trans PF04082.13 KPI41351.1 - 1.5e-16 60.0 0.0 2.1e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ALIX_LYPXL_bnd PF13949.1 KPI41352.1 - 1.2e-69 234.4 14.9 1.7e-69 234.0 10.3 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Med30 PF11315.3 KPI41352.1 - 0.039 14.1 1.4 0.11 12.6 1.0 1.7 1 0 0 1 1 1 0 Mediator complex subunit 30 DEAD PF00270.24 KPI41353.1 - 2.4e-38 131.2 1.6 3.4e-19 68.9 0.2 2.4 1 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI41353.1 - 1.1e-16 60.4 0.0 2.8e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI41353.1 - 1.2e-08 34.9 0.3 1.1e-07 31.8 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KPI41353.1 - 0.0016 17.3 0.1 0.003 16.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 KPI41353.1 - 0.0026 16.2 0.0 0.11 10.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) Flavi_DEAD PF07652.9 KPI41353.1 - 0.076 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain cNMP_binding PF00027.24 KPI41354.1 - 1.9e-38 130.1 0.0 1.2e-19 69.8 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 KPI41354.1 - 1.2e-07 30.9 0.2 2.3e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit COX6B PF02297.12 KPI41355.1 - 3.5e-22 78.2 3.9 4.5e-22 77.8 2.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb UPF0158 PF03682.8 KPI41355.1 - 0.053 13.1 0.5 0.068 12.7 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) TRM PF02005.11 KPI41357.1 - 1.8e-103 346.3 0.0 2.9e-91 306.1 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 KPI41357.1 - 0.002 18.1 0.1 0.0064 16.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KPI41357.1 - 0.004 16.7 0.0 0.0075 15.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 KPI41357.1 - 0.078 12.3 0.2 0.72 9.2 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase small domain Cyto_heme_lyase PF01265.12 KPI41358.1 - 7.5e-72 242.0 0.0 9.1e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase CP2 PF04516.10 KPI41359.1 - 7.8e-81 270.6 0.0 1.4e-80 269.7 0.0 1.4 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.9 KPI41359.1 - 0.062 11.8 0.0 0.094 11.2 0.0 1.2 1 0 0 1 1 1 0 Tektin family Glyco_hydro_10 PF00331.15 KPI41360.1 - 1.5e-109 365.9 3.3 1.7e-109 365.7 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase-like PF12876.2 KPI41360.1 - 0.021 15.2 0.0 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 KPI41360.1 - 0.059 12.4 0.1 0.27 10.3 0.0 1.9 1 1 1 2 2 2 0 Beta-galactosidase DEAD PF00270.24 KPI41361.1 - 1.1e-45 155.2 0.0 3.1e-44 150.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI41361.1 - 7.6e-28 96.2 0.0 2.2e-27 94.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI41361.1 - 0.00017 21.5 0.0 0.00058 19.7 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KPI41361.1 - 0.00067 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 KPI41361.1 - 0.0048 15.3 0.0 0.094 11.0 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) PAS_10 PF13596.1 KPI41361.1 - 0.051 13.8 0.3 0.21 11.8 0.1 2.1 2 0 0 2 2 2 0 PAS domain Ribonuc_L-PSP PF01042.16 KPI41362.1 - 6e-17 61.5 0.0 8.1e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP HMG-CoA_red PF00368.13 KPI41363.1 - 3.8e-157 522.7 3.9 5.8e-157 522.1 2.7 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 KPI41363.1 - 5.4e-41 139.8 1.1 9.8e-41 138.9 0.8 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif adh_short PF00106.20 KPI41363.1 - 1.8e-20 73.4 0.3 4.1e-20 72.3 0.2 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Sterol-sensing PF12349.3 KPI41363.1 - 1.9e-14 53.4 4.0 1.5e-06 27.7 0.4 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KPI41363.1 - 8.6e-08 30.5 3.5 8.6e-08 30.5 2.5 1.4 2 0 0 2 2 2 1 Patched family DUF1776 PF08643.5 KPI41363.1 - 1.7e-07 30.6 0.0 2.8e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KPI41363.1 - 1.5e-06 28.3 3.3 2.6e-06 27.5 0.0 2.9 3 0 0 3 3 3 1 NADH(P)-binding FAD_binding_3 PF01494.14 KPI41363.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 KPI41363.1 - 0.065 12.6 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Aldedh PF00171.17 KPI41364.1 - 9.5e-122 406.6 2.7 1.1e-121 406.4 1.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-H2C2_2 PF13465.1 KPI41365.1 - 2.3e-10 40.2 15.8 7.3e-06 26.0 2.6 4.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KPI41365.1 - 2.7e-05 24.1 13.0 0.017 15.3 1.0 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI41365.1 - 3.2e-05 23.9 13.5 0.0013 18.9 1.3 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KPI41365.1 - 0.36 11.0 2.5 0.35 11.0 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Bud13 PF09736.4 KPI41366.1 - 3.9e-39 134.2 12.1 3.9e-39 134.2 8.4 2.9 3 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex SPATIAL PF15256.1 KPI41366.1 - 0.21 11.6 2.4 0.34 10.9 1.7 1.4 1 0 0 1 1 1 0 SPATIAL NUDIX PF00293.23 KPI41367.1 - 3.3e-11 42.9 0.0 5.1e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain TipAS PF07739.8 KPI41367.1 - 0.017 15.4 0.1 0.036 14.3 0.1 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain TRM13 PF05206.9 KPI41367.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 RCC1 PF00415.13 KPI41368.1 - 2.5e-29 101.2 0.4 5.1e-07 29.8 0.0 6.9 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KPI41368.1 - 4.9e-15 54.6 15.0 1.5e-08 33.9 0.0 7.0 7 0 0 7 7 7 2 Regulator of chromosome condensation (RCC1) repeat HDC PF02329.11 KPI41368.1 - 0.032 12.8 0.0 0.064 11.8 0.0 1.5 1 0 0 1 1 1 0 Histidine carboxylase PI chain Beach PF02138.13 KPI41369.1 - 3.6e-109 364.3 0.0 6.1e-109 363.6 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 KPI41369.1 - 2.3e-12 46.6 0.3 8e-12 44.9 0.0 2.1 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH eIF-5a PF01287.15 KPI41369.1 - 0.00074 19.4 0.0 0.0037 17.1 0.0 2.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold WD40 PF00400.27 KPI41369.1 - 0.0021 17.8 0.0 0.27 11.1 0.2 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat ATP_sub_h PF10775.4 KPI41369.1 - 0.2 11.4 0.8 5.7 6.7 0.0 2.8 3 0 0 3 3 3 0 ATP synthase complex subunit h Ydc2-catalyt PF09159.5 KPI41370.1 - 1.3e-67 228.2 0.0 1.7e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 KPI41370.1 - 1.4e-06 28.2 0.0 0.38 10.6 0.0 3.3 3 0 0 3 3 3 3 Poxvirus A22 protein SAP PF02037.22 KPI41370.1 - 0.0016 17.8 0.2 0.0046 16.4 0.1 1.8 1 0 0 1 1 1 1 SAP domain Abhydrolase_4 PF08386.5 KPI41371.1 - 3.3e-16 59.0 0.2 1.1e-15 57.3 0.1 1.9 1 1 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KPI41371.1 - 2.3e-12 46.9 0.0 2.5e-08 33.7 0.0 3.0 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI41371.1 - 1.1e-05 25.5 1.4 0.001 19.0 1.0 3.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family WH1 PF00568.18 KPI41372.1 - 6e-26 90.3 0.0 9.3e-26 89.7 0.0 1.3 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 KPI41372.1 - 0.022 14.3 6.9 0.17 11.5 4.8 2.3 1 1 0 1 1 1 0 WH2 motif Epimerase PF01370.16 KPI41373.1 - 4.7e-20 72.0 0.0 6.7e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI41373.1 - 1.5e-09 37.0 0.0 1.6e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KPI41373.1 - 6.7e-07 28.4 0.0 0.019 13.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 KPI41373.1 - 3.1e-06 27.2 0.0 0.0084 16.0 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase RmlD_sub_bind PF04321.12 KPI41373.1 - 1.4e-05 24.1 0.0 5.1e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KPI41373.1 - 0.0012 18.8 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KPI41373.1 - 0.0024 16.8 0.0 0.014 14.3 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 KPI41373.1 - 0.0027 17.3 0.0 0.098 12.3 0.0 2.3 1 1 1 2 2 2 1 KR domain Ldh_1_N PF00056.18 KPI41373.1 - 0.0032 17.2 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DUF1690 PF07956.6 KPI41374.1 - 3.1e-27 95.2 7.3 6.3e-15 55.3 0.8 2.0 1 1 1 2 2 2 2 Protein of Unknown function (DUF1690) BRO1 PF03097.13 KPI41374.1 - 0.049 12.3 3.0 0.032 12.9 0.4 1.7 1 1 1 2 2 2 0 BRO1-like domain FliG_C PF01706.11 KPI41374.1 - 0.062 13.2 1.6 0.23 11.4 0.2 2.1 2 0 0 2 2 2 0 FliG C-terminal domain DUF445 PF04286.7 KPI41374.1 - 0.13 11.7 2.3 0.17 11.4 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) RPW8 PF05659.6 KPI41374.1 - 0.15 11.6 2.3 0.13 11.8 0.5 1.7 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Peptidase_S64 PF08192.6 KPI41374.1 - 0.17 10.1 3.0 0.21 9.8 2.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 pRN1_helical PF13010.1 KPI41374.1 - 0.35 10.4 5.3 1.3 8.6 0.9 2.2 2 0 0 2 2 2 0 Primase helical domain DUF964 PF06133.6 KPI41374.1 - 0.36 10.8 6.8 3.4 7.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF964) DUF87 PF01935.12 KPI41374.1 - 0.52 10.0 4.5 3.6 7.3 3.2 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF87 MatP PF06303.7 KPI41374.1 - 1.5 8.6 5.1 0.26 11.1 0.7 1.7 2 0 0 2 2 2 0 Organiser of macrodomain of Terminus of chromosome DUF4404 PF14357.1 KPI41374.1 - 2.9 8.3 6.6 6.4 7.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) G-gamma PF00631.17 KPI41374.1 - 9.9 5.9 7.9 0.56 9.9 0.8 2.3 3 0 0 3 3 3 0 GGL domain Hydant_A_N PF05378.8 KPI41376.1 - 2.3e-07 30.5 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region Sugar_tr PF00083.19 KPI41377.1 - 8.6e-74 248.7 23.0 1e-73 248.4 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI41377.1 - 7.4e-17 61.0 37.2 3.5e-08 32.5 11.3 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI41377.1 - 0.0002 19.8 22.2 0.00056 18.4 4.6 2.8 2 2 0 2 2 2 2 MFS/sugar transport protein DUF3309 PF11752.3 KPI41377.1 - 0.15 11.8 3.0 0.5 10.1 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) DUF4131 PF13567.1 KPI41377.1 - 8.3 5.7 12.2 0.79 9.1 1.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) CEP19 PF14933.1 KPI41378.1 - 0.21 11.8 3.7 0.12 12.7 1.0 1.7 2 0 0 2 2 2 0 CEP19-like protein MT PF12777.2 KPI41378.1 - 0.5 9.0 6.7 1 8.0 0.1 2.2 2 0 0 2 2 2 0 Microtubule-binding stalk of dynein motor DUF2823 PF11034.3 KPI41381.1 - 3.8e-30 103.8 14.9 4.3e-30 103.6 10.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) CLP_protease PF00574.18 KPI41381.1 - 0.11 12.0 0.8 0.11 12.1 0.5 1.1 1 0 0 1 1 1 0 Clp protease Fungal_trans_2 PF11951.3 KPI41383.1 - 0.002 16.7 0.3 0.0036 15.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3201 PF11447.3 KPI41383.1 - 0.12 11.7 0.2 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) Glyco_transf_22 PF03901.12 KPI41384.1 - 6.3e-61 206.6 21.9 7.4e-61 206.4 15.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family POP1 PF06978.6 KPI41386.1 - 2.7e-58 196.7 23.0 2.7e-58 196.7 16.0 2.0 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KPI41386.1 - 2.2e-24 85.0 0.3 2.2e-24 85.0 0.2 2.6 2 0 0 2 2 2 1 POPLD (NUC188) domain CDC37_C PF08564.5 KPI41386.1 - 0.32 10.8 7.3 0.56 10.0 0.0 3.9 4 0 0 4 4 4 0 Cdc37 C terminal domain Ferric_reduct PF01794.14 KPI41387.1 - 4.9e-18 65.4 6.2 4.9e-18 65.4 4.3 2.4 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KPI41387.1 - 1.3e-07 31.4 0.0 3.1e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 KPI41387.1 - 0.00011 22.1 0.0 0.31 10.9 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KPI41387.1 - 0.047 14.2 0.0 0.11 13.0 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain COX4_pro PF03626.9 KPI41387.1 - 5.2 7.2 13.0 0.9 9.6 0.4 3.0 3 0 0 3 3 3 0 Prokaryotic Cytochrome C oxidase subunit IV Mpv17_PMP22 PF04117.7 KPI41388.1 - 2.5e-22 78.2 0.9 4e-21 74.4 0.1 2.2 2 0 0 2 2 2 2 Mpv17 / PMP22 family p450 PF00067.17 KPI41389.1 - 1.6e-46 158.7 0.0 5.3e-33 114.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 RRM_2 PF04059.7 KPI41391.1 - 3.7e-35 119.7 0.1 6.4e-35 119.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_5 PF13893.1 KPI41391.1 - 0.00099 18.9 0.2 0.98 9.3 0.0 3.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KPI41391.1 - 0.0031 17.1 0.0 2.1 8.0 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI41391.1 - 0.0059 16.5 0.1 0.16 11.9 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Epimerase PF01370.16 KPI41392.1 - 5.1e-27 94.8 0.0 7.9e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KPI41392.1 - 1.9e-07 30.2 0.0 3.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KPI41392.1 - 4.1e-07 30.1 0.0 1.9e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KPI41392.1 - 5e-07 28.7 0.0 3.2e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KPI41392.1 - 1.7e-05 23.8 0.0 3.3e-05 22.9 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KPI41392.1 - 9.5e-05 21.4 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Alpha-amylase PF00128.19 KPI41393.1 - 7.8e-18 64.9 4.4 8.8e-17 61.4 2.2 2.8 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 KPI41393.1 - 3.3e-15 56.2 0.1 6e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 KPI41393.1 - 0.00098 18.5 0.0 0.59 9.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 DUF4318 PF14201.1 KPI41393.1 - 0.11 12.3 0.3 12 5.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4318) F-box PF00646.28 KPI41394.1 - 0.019 14.5 0.0 0.1 12.2 0.0 2.3 2 0 0 2 2 2 0 F-box domain Basic PF01586.11 KPI41395.1 - 0.63 10.7 4.5 1.4 9.6 3.1 1.5 1 0 0 1 1 1 0 Myogenic Basic domain Fungal_trans PF04082.13 KPI41396.1 - 4.2e-24 84.8 3.4 6.6e-24 84.1 2.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI41396.1 - 8.5e-05 22.3 12.6 8.5e-05 22.3 8.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PTR2 PF00854.16 KPI41396.1 - 0.00039 19.3 0.1 0.00056 18.8 0.1 1.2 1 0 0 1 1 1 1 POT family AMP-binding PF00501.23 KPI41397.1 - 5.5e-78 262.2 0.0 6.9e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI41397.1 - 1.7e-13 51.3 0.2 4.3e-13 50.0 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.1 KPI41398.1 - 8e-26 91.2 0.4 9.6e-26 91.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI41398.1 - 2.5e-19 69.8 0.3 5e-19 68.8 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI41398.1 - 0.00042 20.0 0.1 0.00061 19.4 0.1 1.4 1 0 0 1 1 1 1 KR domain Methyltransf_26 PF13659.1 KPI41398.1 - 0.026 14.5 0.1 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MOZ_SAS PF01853.13 KPI41398.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family PHD PF00628.24 KPI41400.1 - 1.8e-09 37.1 2.0 1.8e-09 37.1 1.4 1.8 2 0 0 2 2 2 1 PHD-finger zf-CW PF07496.10 KPI41400.1 - 0.017 14.8 1.4 0.04 13.6 1.0 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_2 PF13831.1 KPI41400.1 - 0.08 12.2 5.7 0.043 13.1 1.6 2.1 2 0 0 2 2 2 0 PHD-finger VSP PF03302.8 KPI41401.1 - 4.1e-05 22.4 2.2 5.7e-05 21.9 1.5 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein WSC PF01822.14 KPI41402.1 - 1.1e-10 41.2 11.4 1.1e-10 41.2 7.9 1.7 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 KPI41402.1 - 0.031 13.5 4.2 0.066 12.5 2.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 KPI41402.1 - 0.037 13.5 0.1 0.071 12.6 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2029 PF09594.5 KPI41402.1 - 0.075 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) Shisa PF13908.1 KPI41402.1 - 0.077 13.1 0.0 0.077 13.1 0.0 2.5 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 KPI41402.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain P12 PF12669.2 KPI41402.1 - 6.1 7.1 7.8 1.8 8.8 0.3 2.7 2 0 0 2 2 2 0 Virus attachment protein p12 family zf-DHHC PF01529.15 KPI41403.1 - 2.6e-23 82.3 3.1 2.6e-23 82.3 2.1 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase 7tm_1 PF00001.16 KPI41403.1 - 0.011 14.8 1.1 0.21 10.7 0.0 2.4 2 1 1 3 3 3 0 7 transmembrane receptor (rhodopsin family) Coiled-coil_56 PF09813.4 KPI41403.1 - 0.061 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 Herpes_BBRF1 PF04793.7 KPI41403.1 - 0.33 9.6 1.9 0.47 9.1 1.3 1.2 1 0 0 1 1 1 0 BRRF1-like protein MMtag PF10159.4 KPI41404.1 - 8.2e-33 112.2 2.8 8.2e-33 112.2 1.9 2.2 2 0 0 2 2 2 1 Kinase phosphorylation protein Cyclase PF04199.8 KPI41405.1 - 2.2e-14 53.5 0.3 3.5e-14 52.8 0.2 1.3 1 0 0 1 1 1 1 Putative cyclase Zn_clus PF00172.13 KPI41407.1 - 2.8e-09 36.7 9.1 6.4e-09 35.5 6.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KPI41407.1 - 1.3e-06 27.5 0.3 6.5e-06 25.2 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 KPI41409.1 - 1.3e-81 274.4 18.9 1.6e-81 274.2 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI41409.1 - 1.2e-19 70.2 32.2 1.5e-13 50.2 10.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CopD PF05425.8 KPI41409.1 - 6 7.1 11.6 2.1 8.5 0.2 3.1 3 0 0 3 3 3 0 Copper resistance protein D UQ_con PF00179.21 KPI41413.1 - 1.3e-46 157.5 0.0 1.5e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KPI41413.1 - 0.00021 21.0 0.0 0.00029 20.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KPI41413.1 - 0.013 15.2 0.1 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 KPI41413.1 - 0.052 13.4 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain IMS PF00817.15 KPI41414.1 - 5.9e-37 126.7 0.0 1e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KPI41414.1 - 3.9e-12 46.1 0.0 7.3e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KPI41414.1 - 0.0016 18.4 0.0 0.0033 17.3 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif DUF2197 PF09963.4 KPI41414.1 - 0.0024 17.7 0.0 0.0074 16.2 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2197) Pyr_redox_2 PF07992.9 KPI41415.1 - 3.9e-07 30.1 5.4 0.035 13.9 0.0 3.7 2 2 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI41415.1 - 2.9e-06 27.5 1.3 6.8e-06 26.3 0.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI41415.1 - 0.0041 17.2 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI41415.1 - 0.12 11.2 1.2 1.2 7.8 0.3 2.0 1 1 1 2 2 2 0 Glucose inhibited division protein A DUF3425 PF11905.3 KPI41416.1 - 4.6e-16 58.9 0.0 8.9e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KPI41416.1 - 5e-05 23.1 3.5 0.0001 22.1 2.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KPI41416.1 - 0.0076 16.0 5.2 0.014 15.1 3.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Glutaredoxin2_C PF04399.8 KPI41416.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain eIF-1a PF01176.14 KPI41417.1 - 1.2e-28 98.2 0.1 1.7e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Transp_cyt_pur PF02133.10 KPI41418.1 - 5.2e-82 275.7 29.4 2.8e-81 273.3 20.4 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2583 PF10762.4 KPI41418.1 - 0.028 14.5 5.1 0.038 14.1 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Zn_clus PF00172.13 KPI41419.1 - 6.3e-07 29.2 12.0 1.5e-06 28.0 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KPI41419.1 - 1.9e-05 23.4 2.4 2.3e-05 23.2 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain AAA_19 PF13245.1 KPI41419.1 - 0.072 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain HLH PF00010.21 KPI41420.1 - 6.6e-10 38.5 0.3 2.1e-09 36.9 0.2 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ADIP PF11559.3 KPI41420.1 - 0.00025 20.9 0.2 0.00067 19.5 0.2 1.7 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding ERM PF00769.14 KPI41420.1 - 0.0017 17.9 0.5 0.0017 17.9 0.3 2.1 2 1 0 2 2 2 1 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.7 KPI41420.1 - 0.019 14.7 4.3 0.02 14.6 2.0 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 KPI41420.1 - 0.04 12.9 0.8 0.058 12.4 0.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF904 PF06005.7 KPI41420.1 - 0.3 11.4 3.9 0.21 11.8 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Shugoshin_N PF07558.6 KPI41420.1 - 0.53 10.0 4.8 0.58 9.9 0.8 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region S1FA PF04689.8 KPI41421.1 - 0.0036 17.1 0.8 1.4 8.8 0.0 2.6 2 0 0 2 2 2 2 DNA binding protein S1FA Peptidase_S8 PF00082.17 KPI41422.1 - 2.2e-52 177.9 8.4 3.4e-52 177.3 5.8 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KPI41422.1 - 1.6e-17 63.8 0.1 3.3e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 WD40 PF00400.27 KPI41424.1 - 2.7e-14 52.4 13.7 5.4e-06 26.0 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat RWD PF05773.17 KPI41424.1 - 0.017 14.9 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain Gam PF06064.6 KPI41424.1 - 0.064 13.3 0.1 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Host-nuclease inhibitor protein Gam ADH_N PF08240.7 KPI41425.1 - 2.1e-17 62.8 0.4 4.2e-17 61.8 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI41425.1 - 0.0046 16.4 0.0 0.011 15.2 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 KPI41425.1 - 0.068 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S10 PF00450.17 KPI41427.1 - 4.3e-91 306.1 0.2 5.8e-91 305.7 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Gp23 PF07068.6 KPI41427.1 - 0.04 12.4 0.7 0.06 11.8 0.5 1.1 1 0 0 1 1 1 0 Major capsid protein Gp23 Tcp11 PF05794.8 KPI41428.1 - 3.9e-44 151.0 0.0 7.3e-43 146.8 0.0 2.1 1 1 0 1 1 1 1 T-complex protein 11 adh_short_C2 PF13561.1 KPI41430.1 - 1.4e-33 116.6 0.5 1.7e-33 116.3 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI41430.1 - 1.2e-26 93.6 0.7 1.7e-26 93.0 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI41430.1 - 3.8e-07 29.9 0.3 5.5e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_11 PF08241.7 KPI41430.1 - 0.003 18.0 0.0 0.0061 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI41430.1 - 0.0073 16.8 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI41430.1 - 0.042 14.2 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.13 KPI41430.1 - 0.047 13.3 0.1 0.084 12.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_26 PF13659.1 KPI41430.1 - 0.05 13.6 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RIX1 PF08167.7 KPI41431.1 - 3.8e-21 75.4 2.3 4.9e-21 75.0 0.5 2.0 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Fer4_12 PF13353.1 KPI41431.1 - 0.023 14.8 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain YgbA_NO PF11756.3 KPI41432.1 - 0.045 13.7 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Nitrous oxide-stimulated promoter TRAPPC9-Trs120 PF08626.6 KPI41433.1 - 5.3e-113 378.5 0.0 1.2e-105 354.1 0.0 2.0 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Pet127 PF08634.5 KPI41434.1 - 3.2e-109 364.3 1.8 5.4e-109 363.5 1.0 1.6 2 0 0 2 2 2 1 Mitochondrial protein Pet127 RNase_PH PF01138.16 KPI41435.1 - 5.2e-05 23.5 0.2 0.00012 22.4 0.1 1.7 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Hexokinase_2 PF03727.11 KPI41436.1 - 5e-69 232.1 0.1 8.7e-69 231.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KPI41436.1 - 9.5e-66 221.0 0.1 1.4e-65 220.4 0.1 1.3 1 0 0 1 1 1 1 Hexokinase Myosin_head PF00063.16 KPI41438.1 - 5.1e-58 196.7 0.3 8.1e-58 196.0 0.0 1.5 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 KPI41438.1 - 5e-35 119.5 3.4 1.6e-34 117.9 2.3 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 KPI41438.1 - 5.8e-16 56.5 29.0 0.00016 20.9 0.1 6.6 6 0 0 6 6 6 5 IQ calmodulin-binding motif DegQ PF08181.6 KPI41438.1 - 0.031 13.9 0.7 0.13 12.0 0.5 2.1 1 0 0 1 1 1 0 DegQ (SacQ) family Amidohydro_3 PF07969.6 KPI41438.1 - 0.086 12.0 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Amidohydrolase family GAS PF13851.1 KPI41438.1 - 0.92 8.6 24.8 2.5 7.2 14.4 2.9 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 KPI41438.1 - 3.4 6.7 6.6 3.9 6.5 2.2 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Nsp1_C PF05064.8 KPI41438.1 - 3.4 7.3 13.7 0.067 12.8 1.1 3.3 3 0 0 3 3 3 0 Nsp1-like C-terminal region APG6 PF04111.7 KPI41438.1 - 7 5.5 19.6 29 3.5 13.3 2.1 1 1 0 1 1 1 0 Autophagy protein Apg6 Transcrip_reg PF01709.15 KPI41439.1 - 1.4e-57 194.5 4.0 4.1e-56 189.7 2.8 2.0 1 1 0 1 1 1 1 Transcriptional regulator IBN_N PF03810.14 KPI41440.1 - 3.3e-05 23.7 2.7 6.9e-05 22.6 0.7 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3384 PF11864.3 KPI41440.1 - 0.00069 18.2 0.0 0.0024 16.4 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3384) DNA_gyraseB_C PF00986.16 KPI41440.1 - 0.17 11.6 0.1 0.37 10.5 0.1 1.5 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus CN_hydrolase PF00795.17 KPI41441.1 - 1.3e-16 60.5 0.5 5.6e-16 58.4 0.1 2.1 2 1 0 2 2 2 1 Carbon-nitrogen hydrolase Amidohydro_3 PF07969.6 KPI41443.1 - 3.8e-46 158.0 0.5 5e-46 157.7 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 KPI41443.1 - 0.0041 16.8 0.0 0.94 9.0 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Fcf2 PF08698.6 KPI41444.1 - 6.5e-31 106.2 0.4 1.5e-30 105.1 0.3 1.7 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing DUF89 PF01937.14 KPI41444.1 - 0.0074 15.1 0.6 0.0089 14.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF2365 PF10157.4 KPI41445.1 - 0.00014 21.8 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) DUF2217 PF10265.4 KPI41445.1 - 0.0023 16.7 0.8 0.0028 16.5 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) Mnd1 PF03962.10 KPI41445.1 - 0.0055 16.4 0.5 0.009 15.7 0.3 1.3 1 0 0 1 1 1 1 Mnd1 family Dynein_heavy PF03028.10 KPI41445.1 - 0.0065 14.5 0.2 0.0075 14.3 0.1 1.1 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor CDC45 PF02724.9 KPI41445.1 - 0.018 13.0 0.2 0.023 12.7 0.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Seryl_tRNA_N PF02403.17 KPI41445.1 - 0.051 13.5 1.5 0.13 12.2 1.0 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Mating_N PF12731.2 KPI41445.1 - 0.068 13.0 0.9 13 5.7 0.0 2.6 3 0 0 3 3 3 0 Mating-type protein beta 1 Syntaxin-6_N PF09177.6 KPI41445.1 - 0.074 13.4 1.9 0.18 12.2 1.3 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal AATF-Che1 PF13339.1 KPI41445.1 - 0.094 12.8 0.9 0.19 11.8 0.6 1.5 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Hex_IIIa PF02455.11 KPI41445.1 - 0.11 11.1 1.6 6.2 5.3 0.9 2.2 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) DUF2937 PF11157.3 KPI41445.1 - 0.12 11.7 0.2 0.25 10.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Corona_nucleoca PF00937.13 KPI41445.1 - 0.12 11.3 3.9 0.16 10.8 2.7 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein GreA_GreB_N PF03449.10 KPI41445.1 - 0.13 12.3 5.1 0.65 10.1 3.5 2.1 1 1 0 1 1 1 0 Transcription elongation factor, N-terminal Complex1_LYR_2 PF13233.1 KPI41445.1 - 0.14 12.6 0.8 0.27 11.7 0.3 1.7 1 1 1 2 2 2 0 Complex1_LYR-like DUF4407 PF14362.1 KPI41445.1 - 0.18 10.7 2.0 0.27 10.1 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_hydro_12 PF01670.11 KPI41446.1 - 7.5e-15 55.0 0.4 7.3e-14 51.8 0.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Abhydrolase_6 PF12697.2 KPI41448.1 - 1.1e-31 110.5 0.1 1.3e-31 110.2 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI41448.1 - 1.6e-14 53.9 0.0 2e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI41448.1 - 5.3e-12 45.7 0.1 2.2e-11 43.7 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KPI41448.1 - 1.5e-06 27.9 0.0 3.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF900 PF05990.7 KPI41448.1 - 0.013 14.8 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) MRFAP1 PF15155.1 KPI41448.1 - 0.05 13.9 0.0 0.081 13.2 0.0 1.2 1 0 0 1 1 1 0 MORF4 family-associated protein1 LCAT PF02450.10 KPI41448.1 - 0.069 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 KPI41448.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) Acyl-CoA_dh_1 PF00441.19 KPI41450.1 - 7e-41 139.8 0.7 1.1e-40 139.1 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KPI41450.1 - 8.3e-24 84.3 0.0 1.6e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KPI41450.1 - 1.3e-20 72.6 0.3 2.4e-20 71.7 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KPI41450.1 - 5.1e-13 49.4 0.1 8.3e-13 48.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KPI41450.1 - 6.3e-05 22.4 0.3 0.00027 20.4 0.2 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal TniQ PF06527.6 KPI41451.1 - 0.058 13.5 0.6 2.7 8.1 0.1 2.2 1 1 1 2 2 2 0 TniQ Cytochrom_C_2 PF01322.15 KPI41451.1 - 0.51 10.8 13.6 1.8 9.1 5.0 2.1 1 1 1 2 2 2 0 Cytochrome C' DUF883 PF05957.8 KPI41451.1 - 1.8 9.0 11.1 4.8 7.6 2.2 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 KPI41451.1 - 4.2 7.7 13.3 1.3e+04 -3.5 9.2 3.5 1 1 0 1 1 1 0 YtxH-like protein CBFD_NFYB_HMF PF00808.18 KPI41451.1 - 5.2 7.1 5.8 2.2 8.3 0.4 2.4 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4157 PF13699.1 KPI41451.1 - 5.7 7.1 9.2 7.1 6.8 4.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4157) Tape_meas_lam_C PF09718.5 KPI41451.1 - 7.4 6.5 15.1 0.17 11.8 1.8 3.1 2 2 1 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Lactamase_B PF00753.22 KPI41452.1 - 4.4e-08 33.0 0.0 0.0085 15.7 0.0 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI41452.1 - 0.0034 16.9 0.1 0.0062 16.1 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Flavodoxin_1 PF00258.20 KPI41453.1 - 3.2e-24 85.5 0.0 5.7e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 KPI41453.1 - 2.1e-20 73.1 0.0 6.6e-20 71.4 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain GFO_IDH_MocA PF01408.17 KPI41454.1 - 1.9e-27 96.1 0.0 1.6e-26 93.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 KPI41454.1 - 0.025 14.8 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KPI41454.1 - 0.032 14.0 0.1 0.077 12.8 0.1 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KPI41454.1 - 0.098 13.1 0.1 0.44 11.0 0.0 2.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ras PF00071.17 KPI41456.1 - 3.3e-46 156.6 0.1 3.8e-46 156.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KPI41456.1 - 3.2e-16 59.9 0.0 4.5e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KPI41456.1 - 1.4e-07 30.9 0.0 1.5e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KPI41456.1 - 2.4e-06 27.1 0.4 2.3e-05 23.8 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KPI41456.1 - 7.9e-06 25.8 0.0 1.4e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KPI41456.1 - 8.4e-05 21.8 0.1 0.0002 20.6 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 KPI41456.1 - 0.084 12.7 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain CPSase_sm_chain PF00988.17 KPI41457.1 - 1.1e-44 151.0 0.0 1.9e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KPI41457.1 - 1.4e-44 151.8 0.0 2e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KPI41457.1 - 5.5e-05 22.7 0.1 0.0016 17.9 0.0 2.3 1 1 1 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.19 KPI41457.1 - 0.078 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Ipi1_N PF12333.3 KPI41458.1 - 1.8e-17 63.1 0.0 9.3e-17 60.8 0.0 2.1 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Adaptin_N PF01602.15 KPI41458.1 - 0.0028 16.0 0.2 0.0038 15.6 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region U3snoRNP10 PF12397.3 KPI41458.1 - 0.0044 16.9 0.2 0.041 13.8 0.0 2.5 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 KPI41458.1 - 0.0087 16.0 0.6 2.5 8.3 0.1 3.6 3 0 0 3 3 3 1 HEAT repeat CLASP_N PF12348.3 KPI41458.1 - 0.019 14.3 0.2 0.048 13.0 0.1 1.6 1 1 0 1 1 1 0 CLASP N terminal HEAT_2 PF13646.1 KPI41458.1 - 0.048 13.9 0.2 0.22 11.8 0.1 2.2 1 1 1 2 2 2 0 HEAT repeats DUF2435 PF10363.4 KPI41458.1 - 0.075 12.9 0.6 0.44 10.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 KPI41458.1 - 0.29 11.6 2.7 11 6.6 0.2 3.0 2 1 1 3 3 3 0 HEAT-like repeat DUF533 PF04391.7 KPI41459.1 - 0.21 10.9 0.6 0.24 10.7 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF533) Pex2_Pex12 PF04757.9 KPI41460.1 - 2.1e-36 125.4 10.2 2.8e-36 125.0 7.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 KPI41460.1 - 2.8e-11 43.0 9.3 4.8e-11 42.2 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KPI41460.1 - 3.1e-11 43.1 8.8 5.3e-11 42.3 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KPI41460.1 - 1.7e-10 40.3 6.4 2.7e-10 39.7 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI41460.1 - 4.3e-10 39.0 7.3 7.4e-10 38.3 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI41460.1 - 1.2e-08 34.4 6.4 2e-08 33.8 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KPI41460.1 - 6.1e-06 25.8 1.6 8.5e-06 25.3 0.4 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KPI41460.1 - 4.8e-05 23.1 8.7 8.7e-05 22.3 6.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KPI41460.1 - 0.00029 20.5 2.2 0.0006 19.5 1.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KPI41460.1 - 0.00036 20.5 7.9 0.0008 19.4 5.5 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger Herpes_BLLF1 PF05109.8 KPI41460.1 - 0.00097 17.2 3.5 0.0014 16.7 2.4 1.1 1 0 0 1 1 1 1 Herpes virus major outer envelope glycoprotein (BLLF1) zf-Apc11 PF12861.2 KPI41460.1 - 0.0067 16.2 2.5 0.013 15.3 1.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 KPI41460.1 - 0.074 12.5 4.9 0.15 11.5 3.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KPI41460.1 - 0.32 10.6 9.9 0.65 9.6 6.3 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain IBR PF01485.16 KPI41460.1 - 4.8 7.1 8.9 22 5.0 6.2 2.0 1 1 0 1 1 1 0 IBR domain Abhydrolase_6 PF12697.2 KPI41462.1 - 0.01 15.7 0.3 0.034 14.0 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family CorA PF01544.13 KPI41463.1 - 5.9e-41 140.4 0.0 7.7e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Abhydrolase_6 PF12697.2 KPI41464.1 - 1.7e-31 109.8 0.2 2.2e-31 109.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI41464.1 - 6.6e-12 45.4 0.0 4.6e-11 42.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI41464.1 - 4.2e-10 39.5 0.0 2.6e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KPI41464.1 - 1.6e-05 24.6 0.0 3.8e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Putative lysophospholipase DUF1057 PF06342.7 KPI41464.1 - 0.0018 17.1 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Chlorophyllase PF07224.6 KPI41464.1 - 0.01 14.6 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.2 KPI41464.1 - 0.015 14.2 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme FlbD PF06289.6 KPI41464.1 - 0.066 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Flagellar protein (FlbD) FSH1 PF03959.8 KPI41464.1 - 0.15 11.4 0.0 0.72 9.2 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) BTB PF00651.26 KPI41465.1 - 2.4e-23 82.2 0.0 1.5e-11 44.2 0.4 3.3 4 0 0 4 4 4 2 BTB/POZ domain Ank_2 PF12796.2 KPI41465.1 - 7.3e-10 39.0 0.0 1.7e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KPI41465.1 - 4e-09 36.7 0.0 1.1e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 KPI41465.1 - 2.4e-08 33.4 0.1 3.4e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KPI41465.1 - 1.7e-06 28.0 0.0 1.1e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI41465.1 - 0.00076 19.4 0.2 0.023 14.9 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat DUF3342 PF11822.3 KPI41465.1 - 0.045 12.8 0.1 0.081 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) DIOX_N PF14226.1 KPI41466.1 - 4e-29 101.5 0.0 7.3e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI41466.1 - 2.8e-21 75.6 0.0 5.5e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LRR_4 PF12799.2 KPI41467.1 - 0.0054 16.3 0.0 1.1 8.9 0.0 3.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) Ribosomal_L28e PF01778.12 KPI41468.1 - 7.4e-29 100.5 0.3 7.4e-29 100.5 0.2 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 KPI41468.1 - 2e-23 82.3 17.6 2e-23 82.3 12.2 2.4 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 KPI41468.1 - 2.9e-05 23.3 15.4 3.8e-05 22.9 10.6 1.2 1 0 0 1 1 1 1 BUD22 TFIIA PF03153.8 KPI41468.1 - 0.064 13.1 6.9 0.088 12.6 4.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 KPI41468.1 - 0.078 10.8 25.5 0.098 10.5 17.7 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 KPI41468.1 - 8 4.7 25.4 14 3.9 17.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase PF00069.20 KPI41470.1 - 2.2e-69 233.4 0.0 4.1e-69 232.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI41470.1 - 3e-51 173.9 0.0 6e-51 173.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KPI41470.1 - 5.5e-23 81.1 0.4 5.2e-22 78.0 0.0 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 KPI41470.1 - 8.7e-07 28.1 0.0 1.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 KPI41470.1 - 1.5e-06 28.4 0.6 7.1e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Seadorna_VP7 PF07387.6 KPI41470.1 - 0.0094 14.8 0.1 0.016 14.0 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Syntaxin PF00804.20 KPI41470.1 - 0.033 14.3 4.1 0.12 12.5 2.9 1.9 1 0 0 1 1 1 0 Syntaxin APH PF01636.18 KPI41470.1 - 0.33 10.6 4.9 0.19 11.4 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Aldo_ket_red PF00248.16 KPI41471.1 - 4.3e-50 170.1 0.0 5.4e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Peripla_BP_4 PF13407.1 KPI41471.1 - 0.13 11.6 0.0 5.7 6.1 0.0 2.2 1 1 1 2 2 2 0 Periplasmic binding protein domain TatD_DNase PF01026.16 KPI41472.1 - 1.4e-50 171.8 0.0 1.6e-50 171.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase ABC_tran PF00005.22 KPI41474.1 - 2.3e-16 60.3 0.2 1.9e-09 37.8 0.1 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KPI41474.1 - 5.1e-11 43.0 0.4 0.00014 21.9 0.0 2.2 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KPI41474.1 - 0.00068 19.1 0.4 0.0016 17.8 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 KPI41474.1 - 0.00076 18.7 0.1 0.29 10.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.4 KPI41474.1 - 0.00089 18.7 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 KPI41474.1 - 0.0009 18.3 0.0 0.26 10.2 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain DUF3584 PF12128.3 KPI41474.1 - 0.0053 14.1 0.4 0.0071 13.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_25 PF13481.1 KPI41474.1 - 0.008 15.5 0.7 0.029 13.7 0.5 1.9 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 KPI41474.1 - 0.011 15.1 0.1 0.016 14.6 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 KPI41474.1 - 0.017 15.4 0.2 0.032 14.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KPI41474.1 - 0.018 14.2 0.1 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KPI41474.1 - 0.026 14.6 0.7 0.29 11.2 0.5 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KPI41474.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KPI41474.1 - 0.07 13.9 0.3 0.13 13.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.1 KPI41474.1 - 0.09 11.2 0.1 0.13 10.7 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KPI41474.1 - 0.091 12.7 0.1 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 KPI41474.1 - 0.1 12.5 0.6 0.2 11.6 0.2 1.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KPI41474.1 - 0.11 11.9 0.3 0.16 11.4 0.2 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.16 KPI41474.1 - 0.15 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_5 PF07728.9 KPI41474.1 - 0.16 11.7 0.6 1.3 8.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.18 KPI41474.1 - 0.2 11.4 0.2 0.33 10.7 0.2 1.3 1 0 0 1 1 1 0 Dynamin family Pkinase PF00069.20 KPI41475.1 - 3.8e-59 199.9 0.0 5.7e-59 199.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI41475.1 - 4.9e-36 124.1 0.0 9.5e-26 90.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KPI41475.1 - 0.0052 15.7 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF607 PF04678.8 KPI41475.1 - 0.026 14.4 0.7 0.05 13.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF607 NCA2 PF08637.5 KPI41475.1 - 0.033 13.0 0.0 0.061 12.2 0.0 1.4 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 APH PF01636.18 KPI41475.1 - 0.12 12.0 1.3 3.3 7.3 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family LETM1 PF07766.8 KPI41479.1 - 1.8e-107 358.3 0.7 3.6e-107 357.3 0.5 1.5 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 KPI41479.1 - 5.3e-06 25.7 0.1 0.0015 17.9 0.0 3.1 3 0 0 3 3 3 2 SAP domain DDOST_48kD PF03345.9 KPI41480.1 - 4.7e-154 512.9 0.0 5.6e-154 512.7 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Cyclin_N PF00134.18 KPI41481.1 - 0.0061 16.1 0.3 0.3 10.6 0.1 3.1 2 1 0 2 2 2 1 Cyclin, N-terminal domain PsiE PF06146.7 KPI41481.1 - 0.027 14.7 0.6 0.1 12.8 0.0 2.2 2 0 0 2 2 2 0 Phosphate-starvation-inducible E TFIIB PF00382.14 KPI41481.1 - 0.084 12.6 0.1 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Pol_alpha_B_N PF08418.5 KPI41481.1 - 0.091 12.2 0.6 0.13 11.8 0.4 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Acetyltransf_1 PF00583.19 KPI41482.1 - 9.1e-10 38.4 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI41482.1 - 6.3e-06 26.2 0.0 1.4e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KPI41482.1 - 0.00018 21.1 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KPI41482.1 - 0.022 14.8 0.1 0.15 12.1 0.0 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1656 PF07869.7 KPI41483.1 - 0.0034 17.1 0.2 0.006 16.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1656) MFS_1 PF07690.11 KPI41483.1 - 0.028 13.1 1.0 0.036 12.7 0.7 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily His_biosynth PF00977.16 KPI41484.1 - 2.7e-35 121.7 0.0 3.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 KPI41484.1 - 0.0064 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.12 KPI41484.1 - 0.037 13.1 0.0 0.25 10.4 0.0 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI PcrB PF01884.12 KPI41484.1 - 0.087 12.0 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 PcrB family ADH_N PF08240.7 KPI41485.1 - 5.5e-28 96.8 0.8 1.2e-27 95.7 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI41485.1 - 1.8e-11 43.7 0.2 5.7e-08 32.3 0.0 2.5 1 1 1 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KPI41485.1 - 2.8e-10 39.6 1.1 2.8e-10 39.6 0.7 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Methyltransf_18 PF12847.2 KPI41485.1 - 0.00072 20.1 0.0 0.0016 19.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PDZ_2 PF13180.1 KPI41485.1 - 0.024 14.5 0.1 3 7.8 0.0 2.7 2 0 0 2 2 2 0 PDZ domain NADH_4Fe-4S PF10589.4 KPI41485.1 - 0.044 12.9 0.6 0.38 9.9 1.0 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 2-Hacid_dh_C PF02826.14 KPI41485.1 - 0.055 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 KPI41485.1 - 0.13 12.7 0.0 1.1 9.7 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain Aminotran_1_2 PF00155.16 KPI41486.1 - 7.9e-86 288.2 0.0 1e-85 287.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KPI41486.1 - 9.3e-07 27.9 0.0 1.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KPI41486.1 - 2.5e-06 26.0 0.0 4.4e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KPI41486.1 - 9.5e-05 21.5 0.1 0.00035 19.7 0.1 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KPI41486.1 - 0.0072 15.5 0.1 0.015 14.4 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase AA_permease_2 PF13520.1 KPI41489.1 - 1.2e-42 146.0 47.0 1.5e-42 145.6 32.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI41489.1 - 2.7e-16 58.9 39.3 3.6e-16 58.5 27.3 1.1 1 0 0 1 1 1 1 Amino acid permease PMP1_2 PF08114.6 KPI41489.1 - 0.051 13.0 0.2 0.051 13.0 0.2 3.9 4 0 0 4 4 4 0 ATPase proteolipid family adh_short PF00106.20 KPI41490.1 - 2.9e-16 59.8 0.5 5e-16 59.0 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI41490.1 - 2e-07 30.8 0.2 2.8e-07 30.3 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI41490.1 - 8.2e-06 25.4 0.1 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KPI41490.1 - 0.0033 17.2 0.0 0.0043 16.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 KPI41490.1 - 0.11 11.2 0.0 0.27 9.8 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family F-box-like PF12937.2 KPI41491.1 - 2.8e-06 26.9 0.1 7.1e-06 25.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KPI41491.1 - 0.0077 15.8 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain Fungal_trans PF04082.13 KPI41492.1 - 1.4e-24 86.3 0.2 2.1e-24 85.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SNF2_N PF00176.18 KPI41493.1 - 2.9e-67 226.5 0.1 4.1e-67 226.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KPI41493.1 - 1.7e-12 47.1 0.0 3.9e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain zf-C3HC4_2 PF13923.1 KPI41493.1 - 1.6e-09 37.6 12.2 1.6e-09 37.6 8.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KPI41493.1 - 3.8e-09 36.2 11.5 1.4e-08 34.4 8.0 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KPI41493.1 - 5.3e-09 35.6 9.8 5.3e-09 35.6 6.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI41493.1 - 3.2e-07 29.9 10.1 7e-07 28.8 7.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.26 KPI41493.1 - 1.8e-06 27.7 0.0 4.9e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 KPI41493.1 - 2.3e-06 27.1 12.3 2.3e-06 27.1 8.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KPI41493.1 - 2.4e-06 27.2 11.6 5.8e-06 26.0 8.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KPI41493.1 - 1.7e-05 24.8 4.8 4.9e-05 23.3 3.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KPI41493.1 - 0.00045 19.8 8.1 0.00061 19.4 4.5 2.2 2 0 0 2 2 1 1 RING-type zinc-finger U-box PF04564.10 KPI41493.1 - 0.00084 19.2 0.1 0.0036 17.2 0.0 2.1 1 0 0 1 1 1 1 U-box domain zf-P11 PF03854.9 KPI41493.1 - 0.0018 17.7 3.5 0.0018 17.7 2.5 2.1 2 0 0 2 2 2 1 P-11 zinc finger zf-RING_6 PF14835.1 KPI41493.1 - 0.0039 16.9 4.4 0.021 14.6 3.1 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KPI41493.1 - 0.0051 16.6 2.2 0.013 15.3 1.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Pterin_bind PF00809.17 KPI41493.1 - 0.081 12.2 0.2 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Pterin binding enzyme CorA PF01544.13 KPI41495.1 - 2.5e-10 39.8 2.8 1.3e-09 37.5 0.8 2.4 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein AIP3 PF03915.8 KPI41495.1 - 0.011 14.6 5.3 0.019 13.9 3.7 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 DUF1469 PF07332.6 KPI41495.1 - 0.067 12.9 0.8 0.15 11.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) ApoL PF05461.6 KPI41495.1 - 0.43 9.7 10.1 0.41 9.8 1.9 2.2 1 1 1 2 2 2 0 Apolipoprotein L Abhydrolase_6 PF12697.2 KPI41496.1 - 1.6e-12 47.8 0.6 3.3e-12 46.7 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI41496.1 - 1.2e-07 31.5 0.0 2.3e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI41496.1 - 0.0052 16.3 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 KPI41496.1 - 0.11 11.9 0.1 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Peptidase_S9 PF00326.16 KPI41496.1 - 0.16 11.1 0.0 3.6 6.7 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family WD40 PF00400.27 KPI41497.1 - 2.8e-16 58.6 12.4 9e-05 22.2 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Malate_synthase PF01274.17 KPI41498.1 - 5.6e-231 767.0 0.0 6.3e-231 766.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase FlgM PF04316.8 KPI41500.1 - 0.14 12.1 0.5 0.27 11.2 0.3 1.4 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Orbi_NS3 PF01616.11 KPI41500.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Orbivirus NS3 Ribosomal_S30 PF04758.9 KPI41501.1 - 2.5e-29 100.7 7.7 2.9e-29 100.5 5.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 adh_short PF00106.20 KPI41502.1 - 2.1e-13 50.5 0.0 3.7e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI41502.1 - 5.5e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI41502.1 - 0.00033 20.5 0.0 0.00046 20.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Acetyltransf_1 PF00583.19 KPI41503.1 - 0.00018 21.4 0.1 0.00031 20.7 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI41503.1 - 0.00031 20.8 0.1 0.00059 19.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI41503.1 - 0.019 15.0 0.7 0.061 13.4 0.2 2.0 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Redoxin PF08534.5 KPI41504.1 - 1.3e-34 118.8 0.0 1.5e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KPI41504.1 - 1.3e-12 47.4 0.0 1.6e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Cytadhesin_P30 PF07271.6 KPI41505.1 - 3.3 6.9 10.8 5.2 6.2 7.5 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 DEAD PF00270.24 KPI41507.1 - 1.1e-16 60.8 0.1 1.6e-16 60.2 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI41507.1 - 1.7e-14 53.4 0.0 1e-12 47.7 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain MmgE_PrpD PF03972.9 KPI41507.1 - 0.099 10.7 0.1 0.16 10.0 0.1 1.2 1 0 0 1 1 1 0 MmgE/PrpD family Mito_carr PF00153.22 KPI41508.1 - 4.8e-54 180.0 0.3 1.6e-18 66.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ank_5 PF13857.1 KPI41509.1 - 1.4e-05 25.1 0.2 3.2e-05 24.0 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 KPI41509.1 - 1.4e-05 24.6 0.4 3.5e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 KPI41509.1 - 0.00028 21.1 0.0 0.00062 20.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KPI41509.1 - 0.026 14.7 0.1 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.1 KPI41509.1 - 0.06 13.8 0.0 0.17 12.4 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) zf-C2H2_2 PF12756.2 KPI41509.1 - 0.094 12.8 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) NAD_binding_2 PF03446.10 KPI41510.1 - 9.5e-15 54.8 0.0 1.2e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase OCD_Mu_crystall PF02423.10 KPI41510.1 - 1e-05 24.4 0.0 1.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 KPI41510.1 - 0.00051 20.4 0.1 0.00091 19.6 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KPI41510.1 - 0.0033 17.1 0.1 0.005 16.5 0.1 1.4 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SSP160 PF06933.6 KPI41510.1 - 0.0095 13.9 0.1 0.0097 13.9 0.0 1.0 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 zf-Tim10_DDP PF02953.10 KPI41512.1 - 2.8e-20 71.3 2.2 3.4e-20 71.1 1.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3336 PF11815.3 KPI41512.1 - 0.0075 15.7 0.0 0.0086 15.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) SieB PF14163.1 KPI41512.1 - 0.032 13.8 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B DUF842 PF05811.8 KPI41512.1 - 0.047 13.1 1.2 0.085 12.3 0.8 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) FAD_binding_4 PF01565.18 KPI41513.1 - 7e-14 51.4 2.7 1.5e-13 50.3 1.9 1.6 1 0 0 1 1 1 1 FAD binding domain Wbp11 PF09429.5 KPI41514.1 - 3.8e-22 78.0 20.2 1.6e-21 76.0 13.4 2.5 2 0 0 2 2 2 1 WW domain binding protein 11 hNIFK_binding PF12196.3 KPI41514.1 - 0.19 11.1 2.9 2.9 7.3 0.1 2.7 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Axin_b-cat_bind PF08833.5 KPI41515.1 - 0.021 14.5 0.0 12 5.7 0.0 2.9 2 0 0 2 2 2 0 Axin beta-catenin binding domain FAD_binding_3 PF01494.14 KPI41516.1 - 5.6e-09 35.5 0.1 1.9e-08 33.7 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI41516.1 - 0.0041 16.0 0.0 0.0062 15.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_11 PF14833.1 KPI41517.1 - 2.9e-17 62.8 0.0 3.3e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Laminin_G_3 PF13385.1 KPI41518.1 - 7.5e-09 36.0 0.0 1.3e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CRAL_TRIO PF00650.15 KPI41519.1 - 9.8e-24 83.6 0.0 2e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KPI41519.1 - 6.7e-09 35.7 0.0 1.8e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PAT1 PF09770.4 KPI41519.1 - 8.6 4.4 14.2 13 3.8 9.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pept_tRNA_hydro PF01195.14 KPI41520.1 - 3.1e-29 101.7 0.0 1e-28 100.0 0.0 1.7 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PrsW-protease PF13367.1 KPI41521.1 - 0.05 12.7 0.3 0.072 12.2 0.2 1.2 1 0 0 1 1 1 0 Protease prsW family Aldedh PF00171.17 KPI41522.1 - 1.1e-146 488.8 0.0 1.3e-146 488.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KPI41522.1 - 0.037 12.7 0.0 0.12 11.1 0.0 1.8 3 0 0 3 3 3 0 Acyl-CoA reductase (LuxC) AdoMet_MTase PF07757.8 KPI41523.1 - 2.2e-33 114.7 0.0 4.4e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Cyclin_N PF00134.18 KPI41525.1 - 1.2e-06 28.1 0.0 2.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Abhydrolase_6 PF12697.2 KPI41526.1 - 1.5e-27 96.9 0.0 2.1e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI41526.1 - 3.1e-16 59.6 0.0 2.6e-15 56.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI41526.1 - 1.8e-12 47.2 0.0 6.4e-12 45.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KPI41526.1 - 5e-06 26.8 0.0 1.1e-05 25.8 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 KPI41526.1 - 2.1e-05 24.1 0.1 5.3e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 KPI41526.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydro_lipase PF04083.11 KPI41526.1 - 0.016 14.5 0.2 0.05 12.9 0.1 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.3 KPI41526.1 - 0.027 14.3 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 KPI41526.1 - 0.055 12.9 0.0 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thioredoxin PF00085.15 KPI41527.1 - 0.00053 19.6 0.0 0.00096 18.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Fungal_trans PF04082.13 KPI41528.1 - 3.1e-27 95.0 0.9 3.8e-27 94.7 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_kinase PF00696.23 KPI41529.1 - 8.5e-44 149.8 0.2 1.4e-43 149.2 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.1 KPI41529.1 - 1.9e-13 49.7 0.7 2.3e-11 43.0 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 KPI41529.1 - 7.1e-12 44.5 0.2 2.1e-10 39.8 0.0 3.3 3 0 0 3 3 3 1 ACT domain FMN_red PF03358.10 KPI41529.1 - 0.096 12.1 0.1 1.1 8.7 0.0 2.5 3 0 0 3 3 3 0 NADPH-dependent FMN reductase Hydrolase PF00702.21 KPI41530.1 - 3.6e-10 40.6 0.0 6.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KPI41530.1 - 3.9e-05 23.8 0.0 0.00013 22.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KPI41530.1 - 0.0025 17.4 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SPC12 PF06645.8 KPI41531.1 - 8.6e-23 79.9 0.1 1e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Ribosomal_L23eN PF03939.8 KPI41533.1 - 3e-20 71.9 11.8 7.6e-20 70.6 8.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 KPI41533.1 - 6.8e-17 61.1 1.2 1.4e-16 60.2 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 DUF2346 PF09803.4 KPI41534.1 - 1e-07 31.6 0.1 1.5e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) CR6_interact PF10147.4 KPI41534.1 - 0.053 12.8 0.9 0.062 12.6 0.6 1.1 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 AA_permease_2 PF13520.1 KPI41536.1 - 3.1e-95 319.2 40.8 4.1e-95 318.8 28.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI41536.1 - 2.6e-21 75.5 36.4 4.1e-21 74.8 25.2 1.3 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.20 KPI41537.1 - 2.9e-17 63.0 0.3 4.8e-17 62.3 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI41537.1 - 8.2e-05 22.4 0.0 0.0001 22.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI41537.1 - 0.0035 17.0 0.5 0.023 14.3 0.3 2.1 2 1 0 2 2 2 1 KR domain MitMem_reg PF13012.1 KPI41538.1 - 2.3e-15 56.6 0.1 3.7e-15 55.9 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KPI41538.1 - 1.6e-14 53.6 0.0 2.8e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Fasciclin PF02469.17 KPI41541.1 - 2e-43 147.4 0.0 1.3e-23 83.4 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Fungal_trans PF04082.13 KPI41542.1 - 4.4e-28 97.8 0.0 9.5e-28 96.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI41542.1 - 4.3e-09 36.1 13.8 7.5e-09 35.3 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2977 PF11192.3 KPI41542.1 - 0.22 11.3 0.7 0.95 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2977) Glyco_transf_90 PF05686.7 KPI41543.1 - 1.5e-31 109.4 3.0 2.7e-31 108.6 2.1 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 KPI41543.1 - 0.0009 19.4 0.1 0.0037 17.4 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Vps55 PF04133.9 KPI41544.1 - 7.4e-41 138.6 1.8 8e-41 138.5 1.3 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Peptidase_A24 PF01478.13 KPI41544.1 - 0.01 15.9 5.1 0.21 11.7 0.3 2.1 2 0 0 2 2 2 0 Type IV leader peptidase family EpsG PF14897.1 KPI41544.1 - 0.33 9.8 3.6 0.44 9.4 2.5 1.4 1 1 0 1 1 1 0 EpsG family GAS2 PF02187.12 KPI41545.1 - 5.7e-05 22.7 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Abhydrolase_6 PF12697.2 KPI41546.1 - 2.1e-21 76.8 0.4 8.5e-21 74.8 0.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI41546.1 - 2.4e-10 40.3 0.0 7.4e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI41546.1 - 5e-07 29.5 0.0 2.7e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family NAD_binding_1 PF00175.16 KPI41547.1 - 3.1e-09 37.3 0.0 4.4e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Y_phosphatase2 PF03162.8 KPI41548.1 - 1.4e-41 141.6 0.0 2.1e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KPI41548.1 - 1.4e-10 41.6 0.0 2.2e-08 34.5 0.0 2.2 1 1 1 2 2 2 2 Tyrosine phosphatase family DSPc PF00782.15 KPI41548.1 - 5.4e-05 22.7 0.0 7.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KPI41548.1 - 0.052 12.8 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CDKN3 PF05706.7 KPI41548.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) zf-rbx1 PF12678.2 KPI41549.1 - 9.4e-36 121.7 13.5 1.2e-35 121.4 9.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KPI41549.1 - 2.1e-17 62.7 10.3 2.7e-17 62.3 7.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KPI41549.1 - 3.2e-07 30.0 12.2 1.6e-06 27.8 8.5 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KPI41549.1 - 0.0014 18.2 11.6 0.02 14.5 8.0 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KPI41549.1 - 0.003 17.1 9.2 0.23 11.1 6.5 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI41549.1 - 0.07 13.1 13.0 1.6 8.8 9.1 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KPI41549.1 - 0.11 12.5 8.5 0.45 10.5 6.0 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 KPI41549.1 - 0.56 10.2 9.9 1.2 9.1 6.9 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KPI41549.1 - 0.79 9.9 10.5 28 4.9 7.3 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 KPI41549.1 - 1.1 9.0 7.1 1 9.1 1.6 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.1 KPI41549.1 - 1.1 9.0 11.6 9.1 6.1 8.0 2.3 1 1 0 1 1 1 0 zinc-RING finger domain Glycos_transf_1 PF00534.15 KPI41550.1 - 3.2e-18 65.7 0.0 1.1e-17 63.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KPI41550.1 - 2e-10 40.9 0.0 1.6e-08 34.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KPI41550.1 - 9.2e-05 22.6 0.0 0.00025 21.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 IBN_N PF03810.14 KPI41551.1 - 0.052 13.4 0.1 2.6 8.0 0.0 2.6 2 1 0 2 2 2 0 Importin-beta N-terminal domain XPC-binding PF09280.6 KPI41552.1 - 3.7e-22 77.5 16.1 7.3e-22 76.5 11.2 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 KPI41552.1 - 7.2e-21 73.4 0.1 4e-09 36.0 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 KPI41552.1 - 5e-20 70.6 0.1 7.8e-20 70.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KPI41552.1 - 2.9e-08 33.2 0.1 4.5e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 KPI41552.1 - 0.00017 21.1 0.0 0.1 12.2 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain DUF2407 PF10302.4 KPI41552.1 - 0.0019 18.3 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rap1_C PF11626.3 KPI41552.1 - 0.0075 16.1 0.0 1 9.3 0.0 2.5 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rad60-SLD_2 PF13881.1 KPI41552.1 - 0.0098 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KPI41552.1 - 0.07 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain HAD_2 PF13419.1 KPI41554.1 - 2e-29 103.0 0.0 2.5e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KPI41554.1 - 3.5e-05 24.3 0.0 6.9e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KPI41554.1 - 0.0026 17.4 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 KPI41554.1 - 0.036 13.9 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Myosin_head PF00063.16 KPI41555.1 - 1.7e-170 568.4 4.9 2.1e-170 568.1 3.4 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.1 KPI41555.1 - 0.00035 20.6 0.7 0.0032 17.6 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KPI41555.1 - 0.0016 18.1 0.0 0.0042 16.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 KPI41555.1 - 0.0028 17.3 0.3 0.086 12.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 KPI41555.1 - 0.0029 17.0 0.0 0.0048 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain T2SE PF00437.15 KPI41555.1 - 0.0074 15.2 0.0 0.037 12.9 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 KPI41555.1 - 0.011 15.6 0.2 0.034 14.1 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain PhoH PF02562.11 KPI41555.1 - 0.018 14.2 1.7 2.7 7.1 0.0 3.7 4 1 0 4 4 4 0 PhoH-like protein DUF2075 PF09848.4 KPI41555.1 - 0.036 13.0 0.1 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 KPI41555.1 - 0.045 14.0 0.3 0.1 12.8 0.1 1.8 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 KPI41555.1 - 0.048 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain APS_kinase PF01583.15 KPI41555.1 - 0.075 12.6 0.1 0.23 11.1 0.1 1.8 1 1 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.17 KPI41555.1 - 0.086 13.0 0.1 0.54 10.4 0.0 2.3 3 0 0 3 3 2 0 RNA helicase AAA PF00004.24 KPI41555.1 - 0.11 12.7 0.1 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) WD40 PF00400.27 KPI41556.1 - 3.1e-44 147.3 23.0 5.4e-08 32.4 0.0 11.3 12 0 0 12 12 12 8 WD domain, G-beta repeat IncA PF04156.9 KPI41557.1 - 0.07 12.7 0.3 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 IncA protein DUF89 PF01937.14 KPI41558.1 - 1.6e-123 412.0 0.0 1.8e-123 411.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 CMAS PF02353.15 KPI41559.1 - 5.6e-38 130.5 0.2 7e-38 130.2 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 KPI41559.1 - 6.9e-18 64.6 0.0 9.5e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI41559.1 - 3.3e-16 59.5 0.0 5.2e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI41559.1 - 1.4e-15 57.3 0.0 2e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI41559.1 - 3.7e-15 56.4 0.0 6e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI41559.1 - 6.5e-12 45.8 0.0 1e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KPI41559.1 - 6.2e-10 38.7 0.0 1.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KPI41559.1 - 1.9e-07 31.3 0.0 3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI41559.1 - 1.5e-06 28.2 0.0 3.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KPI41559.1 - 2.1e-06 26.9 0.0 6.8e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.13 KPI41559.1 - 0.00029 20.1 0.0 0.00044 19.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase FtsJ PF01728.14 KPI41559.1 - 0.0003 20.8 0.0 0.0018 18.2 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 KPI41559.1 - 0.00032 19.9 0.0 0.00045 19.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 KPI41559.1 - 0.00051 19.1 0.0 0.00076 18.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF938 PF06080.7 KPI41559.1 - 0.0019 17.7 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) MetW PF07021.7 KPI41559.1 - 0.0041 16.5 0.0 0.0071 15.7 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 KPI41559.1 - 0.0086 15.6 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 KPI41559.1 - 0.0091 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB DREV PF05219.7 KPI41559.1 - 0.019 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase GidB PF02527.10 KPI41559.1 - 0.063 12.4 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G FmrO PF07091.6 KPI41559.1 - 0.092 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DNA_methylase PF00145.12 KPI41560.1 - 2.8e-40 138.4 0.0 1.4e-28 100.0 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Methyltransf_26 PF13659.1 KPI41560.1 - 1.5e-05 25.0 0.0 8.8e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_M24 PF00557.19 KPI41562.1 - 1e-40 139.5 0.0 1.7e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KPI41562.1 - 1.4e-21 77.3 0.0 1.8e-20 73.7 0.0 2.4 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Lysine_decarbox PF03641.9 KPI41563.1 - 1.3e-31 109.2 0.1 2.8e-31 108.0 0.0 1.6 1 1 0 1 1 1 1 Possible lysine decarboxylase p450 PF00067.17 KPI41564.1 - 7.2e-51 173.1 0.0 9.7e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_17 PF00332.13 KPI41565.1 - 3.8e-08 32.7 2.5 7.7e-06 25.1 0.5 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 AAA_12 PF13087.1 KPI41566.1 - 6.8e-35 120.2 0.0 1.1e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KPI41566.1 - 3.6e-20 72.5 0.0 1.2e-19 70.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KPI41566.1 - 7.7e-09 35.1 0.0 2.3e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KPI41566.1 - 1.6e-08 34.3 0.0 3.3e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KPI41566.1 - 5.5e-07 29.3 0.0 0.0012 18.4 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 KPI41566.1 - 0.0033 16.7 0.0 0.0067 15.6 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.10 KPI41566.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.24 KPI41566.1 - 0.017 14.6 0.0 0.041 13.3 0.0 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF2075 PF09848.4 KPI41566.1 - 0.018 14.0 0.0 0.39 9.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 KPI41566.1 - 0.022 14.5 0.0 1.8 8.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KPI41566.1 - 0.13 13.0 0.1 1.1 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KPI41566.1 - 0.17 12.0 0.4 1.2 9.3 0.2 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Vanabin-2 PF11437.3 KPI41566.1 - 1.3 9.0 21.0 2.6 8.0 14.6 1.5 1 0 0 1 1 1 0 Vanadium-binding protein 2 UBA PF00627.26 KPI41567.1 - 0.00061 19.5 0.1 0.0018 18.0 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Nucleopor_Nup85 PF07575.8 KPI41567.1 - 0.63 8.1 0.0 0.95 7.5 0.0 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin Hormone_1 PF00103.15 KPI41568.1 - 0.086 12.1 3.2 0.16 11.2 2.2 1.5 1 0 0 1 1 1 0 Somatotropin hormone family ADIP PF11559.3 KPI41568.1 - 0.13 12.1 28.6 0.073 12.9 7.5 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 KPI41568.1 - 0.23 11.8 21.7 0.57 10.5 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 KPI41568.1 - 1.7 7.7 4.6 21 4.1 0.3 2.1 1 1 0 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KPI41568.1 - 6 5.1 25.3 0.21 10.0 10.6 2.0 1 1 1 2 2 2 0 AAA domain Atg14 PF10186.4 KPI41568.1 - 8.5 5.2 21.0 0.91 8.4 9.3 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Proteasome PF00227.21 KPI41569.1 - 4e-50 169.7 0.1 5.2e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KPI41569.1 - 1.3e-11 43.5 0.3 1.3e-11 43.5 0.2 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DER1 PF04511.10 KPI41570.1 - 2.6e-16 59.6 2.7 1.3e-15 57.4 1.0 1.9 1 1 1 2 2 2 1 Der1-like family Sensor PF13796.1 KPI41570.1 - 2.5 7.6 9.2 0.089 12.3 0.9 2.2 2 1 0 2 2 2 0 Putative sensor BTB PF00651.26 KPI41571.1 - 5e-06 26.4 0.0 8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Sugar_tr PF00083.19 KPI41572.1 - 2.8e-82 276.7 26.6 3.2e-82 276.4 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI41572.1 - 1.1e-16 60.4 29.4 2.2e-16 59.5 15.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PDR_assoc PF08370.6 KPI41572.1 - 0.0019 17.6 1.7 0.0073 15.7 1.2 2.0 1 0 0 1 1 1 1 Plant PDR ABC transporter associated DSPc PF00782.15 KPI41572.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Gly_transf_sug PF04488.10 KPI41573.1 - 5.6e-18 65.2 0.0 1.3e-17 64.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KPI41573.1 - 0.17 10.3 3.1 0.19 10.1 0.9 1.7 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain SNase PF00565.12 KPI41576.1 - 5.9e-75 248.4 2.7 6e-22 77.9 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 KPI41576.1 - 1.8e-24 85.9 0.0 3.1e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 KPI41576.1 - 4.3e-05 22.7 0.0 9e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) zf-C2HC5 PF06221.8 KPI41577.1 - 1.2e-21 76.1 5.0 1.9e-21 75.5 3.5 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type ECH PF00378.15 KPI41578.1 - 2.4e-26 92.3 0.0 3.3e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Transp_cyt_pur PF02133.10 KPI41579.1 - 3.8e-82 276.1 31.2 4.5e-82 275.9 21.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pyr_redox_3 PF13738.1 KPI41581.1 - 1.1e-24 87.6 0.0 1.3e-22 80.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI41581.1 - 8.2e-22 77.0 1.1 1.5e-16 59.7 0.1 3.0 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KPI41581.1 - 1.1e-10 41.7 0.0 5.7e-09 36.1 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI41581.1 - 1.1e-07 32.0 0.0 0.059 13.7 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI41581.1 - 1.2e-07 30.9 0.0 2e-05 23.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KPI41581.1 - 8.9e-07 28.8 0.0 0.00091 19.1 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KPI41581.1 - 2.6e-06 26.7 0.1 0.02 13.9 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 KPI41581.1 - 4.1e-06 25.9 0.7 0.017 14.0 0.2 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KPI41581.1 - 1.8e-05 24.0 0.0 0.059 12.4 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KPI41581.1 - 2.2e-05 24.2 4.4 0.024 14.4 1.5 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 KPI41581.1 - 0.00026 20.1 0.0 0.013 14.6 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KPI41581.1 - 0.00052 18.9 1.1 0.023 13.5 0.2 2.8 2 1 0 3 3 3 1 FAD binding domain GIDA PF01134.17 KPI41581.1 - 0.00059 18.8 0.0 0.093 11.5 0.0 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.9 KPI41581.1 - 0.0014 17.2 0.0 0.039 12.4 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KPI41581.1 - 0.0032 16.6 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 2 Thi4 family Lycopene_cycl PF05834.7 KPI41581.1 - 0.036 12.9 0.0 0.23 10.3 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 KPI41581.1 - 0.045 13.3 0.0 2.5 7.7 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KPI41581.1 - 0.076 13.4 0.0 0.67 10.4 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 KPI41581.1 - 0.13 12.0 0.0 5.8 6.7 0.0 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UQ_con PF00179.21 KPI41582.1 - 1e-40 138.4 0.0 1.3e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 KPI41582.1 - 4.9e-06 26.0 0.0 7.7e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 KPI41582.1 - 0.00011 21.9 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KPI41582.1 - 0.014 15.2 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain Glyco_transf_34 PF05637.7 KPI41583.1 - 1.5e-11 44.2 0.2 2e-08 34.0 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family Glyco_transf_8 PF01501.15 KPI41583.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 8 DUF273 PF03314.9 KPI41583.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF273 DUF745 PF05335.8 KPI41584.1 - 0.0018 17.8 3.6 0.0018 17.8 2.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF745) DUF1687 PF07955.6 KPI41585.1 - 4.1e-18 65.6 0.4 1.7e-17 63.6 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.10 KPI41585.1 - 0.012 15.7 0.0 0.24 11.4 0.0 2.4 1 1 1 2 2 2 0 ArsC family PIG-X PF08320.7 KPI41586.1 - 5.7e-46 156.4 0.3 9e-46 155.7 0.2 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 His_Phos_1 PF00300.17 KPI41587.1 - 1.6e-17 64.0 0.0 2.7e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) UCR_Fe-S_N PF10399.4 KPI41587.1 - 0.012 14.7 0.1 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal adh_short PF00106.20 KPI41588.1 - 4.4e-14 52.7 0.0 1.7e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KPI41588.1 - 2.7e-05 23.8 0.0 6.9e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 KR domain Ribosomal_S3Ae PF01015.13 KPI41589.1 - 6.3e-82 273.6 3.9 7.3e-82 273.4 2.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Syntaxin PF00804.20 KPI41589.1 - 0.035 14.2 0.3 0.15 12.2 0.0 2.0 2 1 0 2 2 2 0 Syntaxin CUE PF02845.11 KPI41590.1 - 3.3e-12 45.6 0.0 5.1e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain YrhK PF14145.1 KPI41591.1 - 0.0014 18.2 23.9 0.02 14.5 0.2 4.8 2 2 2 4 4 4 3 YrhK-like protein MFS_1 PF07690.11 KPI41593.1 - 2e-28 99.1 56.6 7.3e-17 61.1 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI41593.1 - 0.00015 20.3 13.1 0.00015 20.3 9.0 2.7 1 1 1 2 2 2 2 MFS/sugar transport protein DUF3353 PF11833.3 KPI41594.1 - 0.0047 16.4 0.5 0.0084 15.5 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3353) Fork_head PF00250.13 KPI41595.1 - 1e-30 105.6 0.1 2.1e-30 104.5 0.1 1.5 1 0 0 1 1 1 1 Fork head domain zf-C2H2 PF00096.21 KPI41596.1 - 6.1e-09 35.6 15.1 3.3e-05 23.9 1.0 3.1 2 1 1 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KPI41596.1 - 1.1e-08 34.9 6.2 1.8e-06 27.9 0.6 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KPI41596.1 - 2.9e-06 27.2 9.8 0.0014 18.7 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KPI41596.1 - 0.03 14.4 2.7 0.45 10.7 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KPI41596.1 - 0.13 12.5 8.0 0.24 11.7 2.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 KPI41596.1 - 1 9.3 5.3 1.8 8.5 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2372 PF10178.4 KPI41597.1 - 0.00031 20.8 0.0 0.0008 19.4 0.0 1.7 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) Peptidase_S49_N PF08496.5 KPI41598.1 - 1.5 8.6 13.0 1.2 8.8 4.4 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal FANCL_C PF11793.3 KPI41598.1 - 5.4 7.0 7.1 40 4.2 0.0 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain STE PF02200.11 KPI41599.1 - 1.1e-60 202.5 0.1 2.3e-60 201.5 0.0 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 KPI41599.1 - 2.3e-11 43.3 11.8 2.3e-06 27.6 1.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI41599.1 - 1.2e-08 34.6 11.1 0.00091 19.4 1.7 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KPI41599.1 - 2.6e-08 33.7 4.0 2.6e-08 33.7 2.8 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KPI41599.1 - 0.0019 18.0 1.5 0.003 17.3 0.2 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger FYDLN_acid PF09538.5 KPI41599.1 - 0.09 13.3 1.6 0.25 11.9 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-TRAF PF02176.13 KPI41599.1 - 0.14 12.5 2.4 0.25 11.7 1.6 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 KPI41599.1 - 0.28 11.3 7.1 0.13 12.4 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KPI41599.1 - 0.36 10.6 3.3 3.2 7.5 2.7 2.3 2 1 1 3 3 3 0 BED zinc finger Ribonuc_L-PSP PF01042.16 KPI41600.1 - 2.2e-09 37.0 0.0 1.5e-05 24.7 0.0 2.5 3 0 0 3 3 3 2 Endoribonuclease L-PSP PaaX_C PF08223.6 KPI41600.1 - 0.071 12.7 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain Pyrid_oxidase_2 PF13883.1 KPI41601.1 - 4.3e-27 94.9 0.0 6.4e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CPSase_L_D2 PF02786.12 KPI41604.1 - 3e-75 252.1 0.1 4.5e-75 251.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KPI41604.1 - 2.2e-37 127.2 0.0 1.3e-36 124.8 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KPI41604.1 - 3e-36 123.8 0.0 9.9e-36 122.2 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KPI41604.1 - 2.4e-20 73.0 0.1 1.9e-19 70.1 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KPI41604.1 - 1.2e-19 70.2 0.0 2.9e-19 68.9 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 KPI41604.1 - 3.2e-12 45.9 1.0 3.2e-12 45.9 0.7 2.2 3 0 0 3 3 3 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KPI41604.1 - 7.5e-12 45.0 0.0 1.5e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KPI41604.1 - 2.4e-09 36.7 0.1 4.4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KPI41604.1 - 9.1e-06 25.2 0.0 2.4e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KPI41604.1 - 1.7e-05 24.7 0.0 3.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KPI41604.1 - 2.1e-05 24.0 1.8 0.00029 20.4 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like GARS_A PF01071.14 KPI41604.1 - 0.00024 20.6 0.3 0.00049 19.7 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.1 KPI41604.1 - 0.084 11.9 0.0 0.24 10.4 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp FMN_dh PF01070.13 KPI41605.1 - 3.7e-98 328.6 0.0 4.9e-98 328.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KPI41605.1 - 1.3e-16 60.1 0.0 2.4e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KPI41605.1 - 4.8e-06 25.7 0.0 8.3e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KPI41605.1 - 0.0062 15.4 0.2 0.01 14.7 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain OmpH PF03938.9 KPI41606.1 - 0.015 15.2 1.0 0.024 14.5 0.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4203 PF13886.1 KPI41607.1 - 3.3e-40 137.8 22.0 4.6e-40 137.3 15.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) CRT10 PF08728.5 KPI41607.1 - 1.7e-12 46.1 0.0 2.1e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 CRT10 E1-E2_ATPase PF00122.15 KPI41608.1 - 1.2e-19 70.2 0.0 2.3e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KPI41608.1 - 0.0024 17.7 0.0 0.0056 16.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit adh_short PF00106.20 KPI41609.1 - 1.6e-09 37.8 0.4 1.2e-08 35.0 0.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Pro_isomerase PF00160.16 KPI41611.1 - 1.2e-51 175.0 0.0 1.3e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2235 PF09994.4 KPI41615.1 - 7.2e-67 225.6 0.0 9.7e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) HEAT PF02985.17 KPI41616.1 - 1.3e-12 46.6 10.6 0.013 15.5 0.0 9.4 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 KPI41616.1 - 1.8e-09 37.7 3.8 1.3e-05 25.3 0.9 7.6 7 2 1 8 8 8 2 HEAT repeats HEAT_EZ PF13513.1 KPI41616.1 - 0.00023 21.5 13.2 0.014 15.9 0.8 8.1 7 1 2 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KPI41616.1 - 0.00028 21.1 0.0 0.07 13.5 0.0 3.7 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region TIP120 PF08623.5 KPI41616.1 - 0.012 15.1 0.6 2.5 7.6 0.0 3.6 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) SseC PF04888.7 KPI41616.1 - 0.084 12.1 1.4 6.5 5.9 0.0 2.7 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Pkinase PF00069.20 KPI41618.1 - 1.1e-63 214.8 0.0 2e-63 214.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI41618.1 - 1.1e-26 93.4 0.0 1.5e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KPI41618.1 - 0.0095 15.0 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KPI41618.1 - 0.015 14.2 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KPI41618.1 - 0.031 14.0 0.9 1.7 8.3 0.0 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family F-box PF00646.28 KPI41620.1 - 0.0043 16.6 0.0 0.032 13.8 0.0 2.4 2 0 0 2 2 2 1 F-box domain DUF2838 PF10998.3 KPI41621.1 - 1e-43 147.7 11.1 1e-43 147.7 7.7 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) OmpH PF03938.9 KPI41621.1 - 0.018 15.0 0.2 0.045 13.7 0.0 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) bZIP_Maf PF03131.12 KPI41621.1 - 4.6 7.6 9.6 0.52 10.6 3.7 1.5 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF3321 PF11968.3 KPI41622.1 - 1.2e-50 172.1 0.0 3.1e-50 170.8 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase (DUF3321) PBP1_TM PF14812.1 KPI41622.1 - 0.12 12.7 1.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ALS_ss_C PF10369.4 KPI41623.1 - 1.1e-19 69.9 0.0 9.1e-18 63.7 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 KPI41623.1 - 2.4e-11 42.8 0.1 7.6e-11 41.2 0.1 1.9 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.1 KPI41623.1 - 6.8e-09 35.4 0.0 1.8e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 ACT domain DUF3484 PF11983.3 KPI41623.1 - 0.0034 18.1 0.0 0.051 14.4 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3484) ACT_6 PF13740.1 KPI41623.1 - 0.03 14.0 0.1 7.3 6.3 0.0 2.7 2 0 0 2 2 2 0 ACT domain Stn1 PF10451.4 KPI41623.1 - 0.096 11.5 0.1 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Telomere regulation protein Stn1 RRM_5 PF13893.1 KPI41624.1 - 0.093 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBFD_NFYB_HMF PF00808.18 KPI41627.1 - 4e-19 68.4 0.6 6.9e-19 67.6 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KPI41627.1 - 1.7e-12 47.2 0.1 2.5e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 KPI41627.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X DUF4106 PF13388.1 KPI41627.1 - 0.53 9.1 12.3 0.88 8.4 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) PAT1 PF09770.4 KPI41627.1 - 5 5.2 18.3 6.7 4.8 12.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_tranf_2_3 PF13641.1 KPI41629.1 - 5.5e-34 117.9 0.0 7.8e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KPI41629.1 - 1.6e-18 67.1 0.3 1.6e-18 67.1 0.2 2.9 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.9 KPI41629.1 - 9.6e-12 44.0 6.7 3.2e-10 38.9 3.3 2.2 1 1 1 2 2 2 2 Cellulose synthase Glycos_transf_2 PF00535.21 KPI41629.1 - 1e-10 41.5 0.0 1.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KPI41629.1 - 4.5e-09 35.8 0.0 7.8e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 KPI41629.1 - 0.0005 18.5 0.0 0.027 12.8 0.1 2.6 3 0 0 3 3 3 1 Chitin synthase BAR PF03114.13 KPI41630.1 - 2.4e-57 194.1 1.6 2.8e-57 193.8 1.1 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 KPI41630.1 - 0.059 12.7 2.8 0.22 10.8 2.0 1.9 1 1 0 1 1 1 0 Arfaptin-like domain DUF2031 PF09592.5 KPI41630.1 - 0.58 9.2 2.6 0.62 9.1 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) DUF3340 PF11818.3 KPI41630.1 - 0.79 9.6 4.6 0.23 11.4 0.3 2.0 2 1 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) IATP PF04568.7 KPI41631.1 - 0.0023 17.8 2.1 0.0023 17.8 1.5 1.7 1 1 1 2 2 2 1 Mitochondrial ATPase inhibitor, IATP Lactamase_B PF00753.22 KPI41632.1 - 2.2e-06 27.4 1.1 8.6e-06 25.5 0.8 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI41632.1 - 3.7e-06 26.6 0.5 4.9e-06 26.2 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KPI41632.1 - 0.071 12.8 0.3 0.087 12.5 0.2 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain SOG2 PF10428.4 KPI41633.1 - 1.6e-86 290.7 2.4 1.6e-86 290.7 1.7 2.4 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 KPI41633.1 - 7.5e-18 63.7 10.9 8.9e-09 34.7 0.8 3.5 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KPI41633.1 - 4.7e-17 61.4 16.7 1.3e-10 40.8 0.9 3.1 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 KPI41633.1 - 2.7e-05 23.5 7.5 0.58 10.4 0.1 5.2 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 KPI41633.1 - 0.0022 17.8 2.2 8.2 7.1 0.0 4.8 5 0 0 5 5 5 1 Leucine rich repeat LRR_5 PF13306.1 KPI41633.1 - 0.048 13.3 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) LRR_6 PF13516.1 KPI41633.1 - 0.11 12.6 3.5 6.4 7.1 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat HET PF06985.6 KPI41634.1 - 2.4e-07 30.9 0.0 4.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1416 PF07210.7 KPI41636.1 - 0.068 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) PPR PF01535.15 KPI41636.1 - 0.087 12.8 0.1 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 PPR repeat tRNA-synt_2b PF00587.20 KPI41638.1 - 6.3e-32 110.5 0.1 1.2e-31 109.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KPI41638.1 - 2.9e-12 46.5 5.3 6.4e-12 45.4 3.7 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain eIF3_N PF09440.5 KPI41638.1 - 0.026 14.7 2.3 0.068 13.3 1.6 1.7 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain CALCOCO1 PF07888.6 KPI41638.1 - 0.055 11.7 4.1 0.077 11.2 2.8 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like UBN2_3 PF14244.1 KPI41638.1 - 0.088 12.3 1.4 0.18 11.3 0.9 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type SE PF08491.5 KPI41639.1 - 7e-101 336.6 0.0 9.7e-101 336.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 KPI41639.1 - 5e-12 45.5 0.2 4.2e-11 42.5 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI41639.1 - 3.7e-06 26.0 0.0 0.0077 15.1 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KPI41639.1 - 0.00033 19.8 0.0 0.00043 19.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI41639.1 - 0.00057 19.8 0.0 0.0012 18.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI41639.1 - 0.0075 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KPI41639.1 - 0.0088 14.9 0.8 0.39 9.4 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 KPI41639.1 - 0.035 13.7 0.1 0.058 13.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KPI41639.1 - 0.043 12.9 1.2 0.42 9.6 0.2 2.3 2 1 0 2 2 2 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 KPI41639.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 KPI41639.1 - 0.11 11.0 1.2 5.4 5.5 0.0 2.1 1 1 1 2 2 2 0 Tryptophan halogenase F420_oxidored PF03807.12 KPI41639.1 - 0.12 12.8 0.1 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.1 KPI41639.1 - 0.14 12.1 0.6 0.53 10.3 0.4 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Cohesin_load PF10345.4 KPI41640.1 - 9.6e-74 248.6 12.8 1.3e-73 248.2 8.9 1.1 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.1 KPI41640.1 - 9.6e-07 28.6 17.1 0.012 15.5 0.5 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 KPI41640.1 - 2.4e-05 23.7 4.8 0.019 14.5 0.3 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KPI41640.1 - 0.00039 19.9 1.8 0.73 9.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KPI41640.1 - 0.00047 19.8 8.5 0.04 13.8 0.2 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KPI41640.1 - 0.14 11.7 20.1 0.32 10.6 0.7 5.4 5 1 1 6 6 6 0 TPR repeat TPR_16 PF13432.1 KPI41640.1 - 0.24 12.1 9.4 3.4 8.4 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat Med6 PF04934.9 KPI41641.1 - 2e-28 98.6 0.0 3e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Roughex PF06020.6 KPI41641.1 - 0.03 12.9 0.5 0.041 12.5 0.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Mid1 PF12929.2 KPI41642.1 - 3.9e-133 444.2 1.3 4.5e-133 444.0 0.9 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 KPI41642.1 - 0.014 15.7 3.2 0.16 12.3 0.3 2.4 2 0 0 2 2 2 0 Fz domain Glyoxalase_2 PF12681.2 KPI41643.1 - 5.6e-11 43.0 0.1 7.6e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KPI41643.1 - 0.00097 19.1 0.1 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KPI41643.1 - 0.051 13.6 0.0 0.066 13.2 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GST_N_3 PF13417.1 KPI41644.1 - 2e-15 56.7 0.0 3.7e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KPI41644.1 - 3e-07 30.2 0.0 5.6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KPI41644.1 - 2.2e-05 24.8 0.0 3.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KPI41644.1 - 0.00013 21.8 0.0 0.0003 20.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KPI41644.1 - 0.0076 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain adh_short_C2 PF13561.1 KPI41645.1 - 9.6e-26 91.0 0.0 1.3e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI41645.1 - 3.2e-21 75.9 0.4 9.5e-19 67.9 0.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI41645.1 - 7.9e-12 45.2 0.1 2.7e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 KR domain Lyase_1 PF00206.15 KPI41647.1 - 1.8e-110 369.0 0.0 2.6e-110 368.5 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 KPI41647.1 - 7.5e-22 77.1 0.0 2.4e-21 75.5 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus Form_Nir_trans PF01226.12 KPI41648.1 - 1.5e-27 96.0 24.5 1.2e-13 50.5 6.5 3.1 2 1 0 2 2 2 2 Formate/nitrite transporter FA_desaturase PF00487.19 KPI41648.1 - 0.025 14.0 4.0 0.065 12.6 0.2 2.2 2 0 0 2 2 2 0 Fatty acid desaturase FUSC_2 PF13515.1 KPI41649.1 - 4.3e-29 101.0 3.8 4.3e-29 101.0 2.7 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 KPI41649.1 - 2.4e-07 29.7 13.0 9.6e-05 21.2 6.8 3.5 3 1 0 3 3 3 2 Aluminium activated malate transporter FUSC PF04632.7 KPI41649.1 - 1.4e-06 27.1 0.3 1.4e-06 27.1 0.2 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein family DUF2421 PF10334.4 KPI41649.1 - 8.3e-06 25.5 0.3 6.6e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) DUF4319 PF14203.1 KPI41649.1 - 0.063 12.8 0.4 5.9 6.5 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4319) DUF1469 PF07332.6 KPI41649.1 - 1 9.1 5.4 4.4 7.0 3.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) OB_NTP_bind PF07717.11 KPI41650.1 - 9e-22 77.0 0.0 1.8e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KPI41650.1 - 8.2e-16 57.8 0.2 1.8e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KPI41650.1 - 4.9e-11 42.3 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KPI41650.1 - 5.4e-06 26.0 0.2 1.1e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KPI41650.1 - 5.9e-06 26.4 0.1 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KPI41650.1 - 0.0031 17.8 1.0 0.043 14.1 0.1 2.8 2 1 0 2 2 2 1 ABC transporter AAA_30 PF13604.1 KPI41650.1 - 0.0038 16.8 0.1 0.0075 15.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.4 KPI41650.1 - 0.0053 15.4 0.1 0.026 13.1 0.1 2.0 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.1 KPI41650.1 - 0.019 15.2 0.0 0.054 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KPI41650.1 - 0.021 13.7 0.1 0.042 12.7 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 KPI41650.1 - 0.027 13.9 0.1 0.079 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KPI41650.1 - 0.072 12.1 0.2 0.26 10.3 0.0 1.9 1 1 1 2 2 2 0 Zeta toxin cobW PF02492.14 KPI41650.1 - 0.093 12.1 0.3 0.36 10.2 0.0 2.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.1 KPI41650.1 - 0.12 11.9 0.1 0.48 9.9 0.0 1.9 1 1 0 2 2 2 0 AAA domain KaiC PF06745.8 KPI41650.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 KaiC MIP PF00230.15 KPI41651.1 - 1.6e-32 112.8 11.4 1.9e-32 112.5 7.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein Tetraspannin PF00335.15 KPI41652.1 - 5.1e-06 25.9 1.9 6.6e-06 25.5 1.3 1.2 1 0 0 1 1 1 1 Tetraspanin family WBP-1 PF11669.3 KPI41652.1 - 0.056 13.5 0.1 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 WW domain-binding protein 1 PH PF00169.24 KPI41653.1 - 0.12 12.6 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 0 PH domain Mob_Pre PF01076.14 KPI41654.1 - 0.013 15.1 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 Plasmid recombination enzyme AurF PF11583.3 KPI41654.1 - 0.1 11.5 0.5 0.14 11.0 0.0 1.4 2 0 0 2 2 2 0 P-aminobenzoate N-oxygenase AurF DKCLD PF08068.7 KPI41655.1 - 3.7e-29 100.4 0.3 7.2e-28 96.3 0.0 2.6 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.13 KPI41655.1 - 1.6e-23 83.4 0.2 8.8e-21 74.6 0.1 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KPI41655.1 - 4.6e-21 74.3 0.9 7.9e-21 73.5 0.6 1.4 1 0 0 1 1 1 1 PUA domain Ribosomal_L24e PF01246.15 KPI41656.1 - 1.2e-29 101.9 0.4 1.2e-29 101.9 0.3 2.1 2 1 0 2 2 2 1 Ribosomal protein L24e PVL_ORF50 PF07768.6 KPI41656.1 - 0.31 11.0 9.6 0.46 10.4 6.7 1.2 1 0 0 1 1 1 0 PVL ORF-50-like family COX16 PF14138.1 KPI41656.1 - 0.45 10.7 5.0 1.1 9.5 0.2 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 DUF2450 PF10475.4 KPI41657.1 - 3.2e-06 26.2 6.2 4.7e-06 25.7 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG5 PF10392.4 KPI41657.1 - 0.0014 18.6 1.8 0.0014 18.6 1.2 2.7 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Sec5 PF15469.1 KPI41657.1 - 0.0032 17.2 7.4 0.0065 16.2 5.1 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG2 PF06148.6 KPI41657.1 - 0.0053 16.6 4.0 0.0053 16.6 2.8 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DASH_Duo1 PF08651.5 KPI41657.1 - 0.013 15.0 4.7 0.064 12.8 1.5 3.2 2 1 1 3 3 3 0 DASH complex subunit Duo1 AAA_5 PF07728.9 KPI41657.1 - 0.051 13.2 0.7 0.12 12.1 0.5 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) K167R PF08065.7 KPI41657.1 - 0.11 12.6 1.5 0.12 12.5 0.1 1.8 2 0 0 2 2 2 0 K167R (NUC007) repeat Sec8_exocyst PF04048.9 KPI41657.1 - 0.15 11.6 9.6 0.24 11.0 4.9 2.6 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain ING PF12998.2 KPI41657.1 - 0.33 11.2 8.7 0.47 10.7 2.5 2.7 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4206 PF13901.1 KPI41657.1 - 0.61 9.5 4.5 0.59 9.6 1.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4206) F-box-like_2 PF13013.1 KPI41658.1 - 0.0023 17.6 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain GHMP_kinases_N PF00288.21 KPI41659.1 - 1.9e-06 27.8 0.0 5.6e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KPI41659.1 - 0.00028 21.0 0.0 0.00067 19.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal adh_short PF00106.20 KPI41660.1 - 8.5e-05 22.5 1.4 0.00011 22.1 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Meth_synt_1 PF08267.7 KPI41661.1 - 5.4e-126 420.0 0.1 5.2e-115 383.9 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Meth_synt_2 PF01717.13 KPI41661.1 - 6.4e-122 406.5 0.1 1e-99 333.5 0.0 3.7 3 1 1 4 4 4 3 Cobalamin-independent synthase, Catalytic domain URO-D PF01208.12 KPI41661.1 - 0.0053 15.7 0.1 2.2 7.1 0.0 3.0 2 1 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) Bac_small_YrzI PF09501.5 KPI41661.1 - 5.7 6.9 9.5 1.8 8.5 2.4 3.0 3 0 0 3 3 3 0 Probable sporulation protein (Bac_small_yrzI) Sec15 PF04091.7 KPI41662.1 - 4.5e-96 321.8 4.7 5.9e-96 321.4 3.2 1.1 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Sec6 PF06046.8 KPI41662.1 - 0.054 11.5 0.6 0.083 10.9 0.1 1.5 2 0 0 2 2 2 0 Exocyst complex component Sec6 Pkinase PF00069.20 KPI41663.1 - 3.2e-70 236.2 0.0 5.4e-70 235.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI41663.1 - 8.6e-37 126.6 0.0 1.5e-34 119.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KPI41663.1 - 0.00015 20.9 0.0 0.00059 18.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KPI41663.1 - 0.00059 19.6 0.1 0.0026 17.5 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KPI41663.1 - 0.0031 17.1 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 KPI41663.1 - 0.021 13.8 0.0 0.078 11.9 0.0 2.0 2 0 0 2 2 2 0 Kinase-like NIF PF03031.13 KPI41664.1 - 1.4e-53 180.8 0.0 2.2e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF605 PF04652.11 KPI41664.1 - 0.0082 15.5 6.3 0.012 15.0 4.4 1.2 1 0 0 1 1 1 1 Vta1 like DUF4629 PF15442.1 KPI41664.1 - 6.4 6.8 10.3 18 5.4 7.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4629) DUF3317 PF11779.3 KPI41666.1 - 1.5e-18 65.9 3.8 2.1e-18 65.5 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) DUF1624 PF07786.7 KPI41666.1 - 0.0054 16.0 0.8 0.0065 15.8 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1624) Cytochrom_B558a PF05038.8 KPI41666.1 - 0.061 12.9 0.2 0.084 12.4 0.2 1.2 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit ABM PF03992.11 KPI41668.1 - 0.05 13.6 0.0 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Glyco_transf_49 PF13896.1 KPI41668.1 - 0.061 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan DUF4605 PF15378.1 KPI41669.1 - 0.0069 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4605) Isochorismatase PF00857.15 KPI41670.1 - 8.8e-38 129.9 0.0 1e-37 129.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF87 PF01935.12 KPI41670.1 - 0.0098 15.7 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF87 Lys-AminoMut_A PF09043.6 KPI41670.1 - 0.035 12.2 0.0 0.046 11.8 0.0 1.3 1 1 0 1 1 1 0 D-Lysine 5,6-aminomutase alpha subunit Peripla_BP_6 PF13458.1 KPI41670.1 - 0.052 12.8 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein HALZ PF02183.13 KPI41671.1 - 2.6e-06 27.0 5.3 0.013 15.2 1.1 4.2 4 1 0 4 4 4 3 Homeobox associated leucine zipper APG6 PF04111.7 KPI41671.1 - 0.042 12.9 4.2 2.5 7.0 0.0 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 KPI41671.1 - 0.23 9.2 0.3 0.33 8.7 0.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-Q PF13094.1 KPI41671.1 - 0.82 9.6 8.6 1.3 9.0 4.5 2.3 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit PAP_assoc PF03828.14 KPI41672.1 - 1.9e-16 59.7 0.0 5.1e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KPI41672.1 - 4.8e-06 26.8 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Fungal_trans PF04082.13 KPI41673.1 - 0.0001 21.3 0.3 0.00028 19.8 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF917 PF06032.7 KPI41674.1 - 1.1e-104 349.8 0.1 1.5e-104 349.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 KPI41674.1 - 8.9e-40 136.5 1.6 1.7e-39 135.6 1.1 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase StbA PF06406.6 KPI41674.1 - 0.0044 16.0 0.6 2.4 6.9 0.0 2.5 3 0 0 3 3 3 2 StbA protein DUF1731 PF08338.6 KPI41674.1 - 0.15 11.6 0.0 0.36 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) TRAM_LAG1_CLN8 PF03798.11 KPI41675.1 - 7.2e-39 133.4 15.2 7.2e-39 133.4 10.6 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KPI41675.1 - 3.6e-20 71.2 0.6 8.9e-20 69.9 0.4 1.7 1 0 0 1 1 1 1 TRAM1-like protein NmrA PF05368.8 KPI41676.1 - 1.2e-27 96.6 0.0 1.5e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI41676.1 - 3.3e-08 33.7 0.0 5.2e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KPI41676.1 - 4e-05 23.8 0.0 7.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 KPI41676.1 - 0.00035 20.5 0.2 0.00094 19.1 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain KR PF08659.5 KPI41676.1 - 0.0027 17.4 0.1 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KPI41676.1 - 0.0045 17.0 0.0 0.0087 16.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KPI41676.1 - 0.011 15.6 0.2 0.019 14.8 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 KPI41676.1 - 0.056 12.1 0.0 0.085 11.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sec16_C PF12931.2 KPI41677.1 - 1.9e-89 300.2 0.0 2.6e-89 299.7 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 KPI41677.1 - 2e-28 98.6 0.0 4.3e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region MraY_sig1 PF10555.4 KPI41677.1 - 0.25 10.7 2.3 1.1 8.6 1.6 2.3 1 0 0 1 1 1 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 ERCC4 PF02732.10 KPI41678.1 - 7e-23 80.9 0.0 1.8e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain p450 PF00067.17 KPI41679.1 - 5.5e-72 242.7 0.0 1e-71 241.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 MARVEL PF01284.18 KPI41680.1 - 0.0017 18.1 10.9 0.0026 17.5 7.1 1.6 1 1 0 1 1 1 1 Membrane-associating domain NfeD PF01957.13 KPI41680.1 - 0.049 13.7 1.2 0.45 10.6 0.0 2.1 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding G10 PF01125.12 KPI41681.1 - 2.1e-56 189.5 3.4 3.2e-56 188.9 2.3 1.2 1 0 0 1 1 1 1 G10 protein P5-ATPase PF12409.3 KPI41682.1 - 1.9e-33 114.8 0.0 4.1e-33 113.7 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 KPI41682.1 - 2.3e-32 112.7 0.0 4.3e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KPI41682.1 - 2.4e-24 85.6 0.1 8.4e-24 83.8 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KPI41682.1 - 1e-14 55.5 0.0 5.5e-13 49.8 0.0 3.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KPI41682.1 - 0.0027 17.6 0.0 0.0063 16.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KPI41682.1 - 0.0049 16.3 0.0 0.015 14.7 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KPI41682.1 - 0.016 14.8 0.0 0.39 10.2 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase SMC_N PF02463.14 KPI41684.1 - 1.3e-41 142.2 0.0 6.2e-41 140.0 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KPI41684.1 - 6.4e-14 51.9 0.0 3.7e-13 49.4 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KPI41684.1 - 1.5e-05 25.1 1.8 3.6e-05 23.8 0.0 2.5 3 1 0 3 3 3 1 AAA domain Reo_sigmaC PF04582.7 KPI41684.1 - 7.6e-05 22.0 20.8 0.046 12.8 1.5 4.9 4 1 1 5 5 5 3 Reovirus sigma C capsid protein SbcCD_C PF13558.1 KPI41684.1 - 0.00026 20.8 0.1 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit IncA PF04156.9 KPI41684.1 - 0.0007 19.2 92.0 0.018 14.6 7.8 6.1 4 2 2 6 6 5 4 IncA protein DUF3037 PF11236.3 KPI41684.1 - 0.03 14.3 0.5 0.03 14.3 0.3 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3037) DUF869 PF05911.6 KPI41684.1 - 0.57 8.3 72.3 0.036 12.3 9.3 4.2 3 1 1 4 4 4 0 Plant protein of unknown function (DUF869) FlaC_arch PF05377.6 KPI41684.1 - 2.4 8.1 26.9 2 8.3 0.5 7.0 6 1 0 6 6 6 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 KPI41684.1 - 3.4 7.4 28.3 1.1 9.0 0.1 6.5 4 2 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 KPI41684.1 - 5.6 5.5 90.3 0.5 8.9 2.0 6.4 3 2 2 6 6 6 0 Spc7 kinetochore protein PTCB-BRCT PF12738.2 KPI41685.1 - 2.1e-14 53.0 0.0 3.4e-13 49.2 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 KPI41685.1 - 7e-10 38.9 0.0 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 KPI41685.1 - 0.0019 17.9 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.16 KPI41685.1 - 0.008 16.2 0.1 0.027 14.5 0.0 1.9 1 1 0 1 1 1 1 Fibronectin type III domain PAT1 PF09770.4 KPI41685.1 - 0.69 8.0 12.6 0.94 7.6 8.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Epimerase PF01370.16 KPI41687.1 - 0.00022 20.7 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI41687.1 - 0.0094 15.9 0.0 0.022 14.7 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KPI41687.1 - 0.016 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 KPI41687.1 - 0.06 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 KR domain NmrA PF05368.8 KPI41687.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.7 KPI41687.1 - 0.17 10.7 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Ham1p_like PF01725.11 KPI41688.1 - 1.6e-41 141.7 0.0 1.1e-40 138.9 0.0 1.9 1 1 0 1 1 1 1 Ham1 family GFA PF04828.9 KPI41689.1 - 1e-16 60.6 0.1 2.3e-16 59.4 0.1 1.6 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 KPI41689.1 - 0.012 15.4 1.3 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF2321 PF10083.4 KPI41689.1 - 0.069 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Nudix_N_2 PF14803.1 KPI41689.1 - 0.088 12.5 0.0 0.088 12.5 0.0 2.2 2 0 0 2 2 2 0 Nudix N-terminal MIP PF00230.15 KPI41690.1 - 1.1e-26 93.7 8.9 1.5e-26 93.2 6.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein NAP PF00956.13 KPI41691.1 - 1.2e-87 293.0 9.0 1.2e-87 293.0 6.3 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF2457 PF10446.4 KPI41691.1 - 0.29 9.8 32.3 0.023 13.4 14.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Pkinase PF00069.20 KPI41692.1 - 1.3e-65 221.1 0.0 1.7e-65 220.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI41692.1 - 2.6e-31 108.6 0.0 4.7e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI41692.1 - 0.0017 17.3 0.0 0.0093 14.9 0.0 2.1 1 1 0 1 1 1 1 Kinase-like AAA_18 PF13238.1 KPI41693.1 - 8.1e-19 68.2 0.3 3.2e-08 33.9 0.0 2.4 2 1 1 3 3 2 2 AAA domain AAA_17 PF13207.1 KPI41693.1 - 9.9e-08 32.8 0.5 3.9e-07 30.9 0.3 2.1 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KPI41693.1 - 0.00016 21.3 0.2 0.0004 20.1 0.1 1.6 1 0 0 1 1 1 1 NTPase AAA_28 PF13521.1 KPI41693.1 - 0.0006 19.8 0.4 0.0015 18.5 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KPI41693.1 - 0.00083 19.3 0.0 0.002 18.1 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KPI41693.1 - 0.00091 19.3 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KPI41693.1 - 0.001 18.7 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KPI41693.1 - 0.0016 18.8 0.0 0.0034 17.8 0.0 1.6 1 1 1 2 2 2 1 Miro-like protein AAA PF00004.24 KPI41693.1 - 0.0034 17.6 0.0 0.0054 16.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KPI41693.1 - 0.0039 16.9 0.2 0.0089 15.7 0.1 1.6 2 0 0 2 2 1 1 Part of AAA domain MMR_HSR1 PF01926.18 KPI41693.1 - 0.0057 16.6 0.1 0.0088 15.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 KPI41693.1 - 0.0074 15.8 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.4 KPI41693.1 - 0.0077 14.8 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 KPI41693.1 - 0.0087 15.5 0.1 0.021 14.3 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family cobW PF02492.14 KPI41693.1 - 0.021 14.3 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 KPI41693.1 - 0.023 14.1 0.0 0.044 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_11 PF13086.1 KPI41693.1 - 0.023 14.2 0.2 0.031 13.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KPI41693.1 - 0.024 14.5 0.0 0.065 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KPI41693.1 - 0.026 13.9 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 KPI41693.1 - 0.029 14.2 0.0 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KPI41693.1 - 0.03 13.0 1.4 0.13 11.0 0.1 2.0 2 0 0 2 2 2 0 ArgK protein KTI12 PF08433.5 KPI41693.1 - 0.046 12.9 0.1 0.1 11.7 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_5 PF07728.9 KPI41693.1 - 0.05 13.3 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 KPI41693.1 - 0.058 13.0 0.0 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain T2SE PF00437.15 KPI41693.1 - 0.06 12.2 1.0 0.074 11.9 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.1 KPI41693.1 - 0.093 12.3 0.1 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KPI41693.1 - 0.12 12.6 0.2 0.17 12.1 0.1 1.6 1 1 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 KPI41693.1 - 0.19 11.1 0.5 1.9 7.8 0.0 2.3 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain CASP_C PF08172.7 KPI41694.1 - 0.012 14.6 0.1 0.038 13.0 0.0 1.9 1 0 0 1 1 1 0 CASP C terminal DUF3684 PF12449.3 KPI41695.1 - 0 1360.4 0.0 0 1360.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 KPI41695.1 - 1.5e-05 24.6 0.0 3.3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KPI41695.1 - 3.3e-05 23.5 0.0 7.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.5 KPI41695.1 - 0.065 13.0 1.4 1.7 8.4 0.1 2.6 2 0 0 2 2 2 0 WLM domain Selenoprotein_S PF06936.6 KPI41695.1 - 0.093 12.2 2.2 0.28 10.7 1.5 1.7 1 0 0 1 1 1 0 Selenoprotein S (SelS) SAM_PNT PF02198.11 KPI41695.1 - 1.1 9.0 6.2 7.1 6.4 0.1 3.2 4 0 0 4 4 4 0 Sterile alpha motif (SAM)/Pointed domain Med3 PF11593.3 KPI41696.1 - 0.0001 21.7 13.5 0.00011 21.6 9.3 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal RNA_polI_A34 PF08208.6 KPI41696.1 - 0.00025 20.7 6.4 0.00033 20.3 4.4 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 SR-25 PF10500.4 KPI41696.1 - 0.00043 19.8 2.2 0.00043 19.8 1.6 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Med19 PF10278.4 KPI41696.1 - 0.0031 17.2 10.0 0.0044 16.7 7.0 1.1 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 BLVR PF06375.6 KPI41696.1 - 0.0064 16.3 4.5 0.0086 15.9 3.1 1.3 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) Dicty_REP PF05086.7 KPI41696.1 - 0.038 11.7 12.4 0.045 11.5 8.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3464 PF11947.3 KPI41696.1 - 0.041 13.3 5.1 0.083 12.3 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Tim54 PF11711.3 KPI41696.1 - 0.077 11.5 4.8 0.094 11.2 3.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S49_N PF08496.5 KPI41696.1 - 0.81 9.4 5.6 1.2 8.8 3.9 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ORC6 PF05460.8 KPI41696.1 - 1.2 8.1 10.6 1.3 8.0 7.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Herpes_DNAp_acc PF04929.7 KPI41696.1 - 4.6 6.1 11.6 5.7 5.8 8.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RNase_H2-Ydr279 PF09468.5 KPI41696.1 - 4.6 6.3 11.7 6.1 5.9 8.1 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) FH2 PF02181.18 KPI41697.1 - 5.7e-79 265.6 3.4 5.7e-79 265.6 2.3 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 KPI41697.1 - 1.8e-65 219.8 0.1 1.8e-65 219.8 0.0 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 KPI41697.1 - 1.7e-53 180.9 4.2 2.2e-52 177.3 0.7 3.6 2 1 1 3 3 3 1 Diaphanous FH3 Domain DUF1479 PF07350.7 KPI41698.1 - 2.7e-162 540.0 0.0 3.1e-162 539.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Glyco_hydro_42 PF02449.10 KPI41699.1 - 1.2e-10 41.1 0.0 1.8e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.14 KPI41699.1 - 5.5e-10 39.1 0.0 1.8e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.15 KPI41699.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Suf PF05843.9 KPI41700.1 - 1.6e-62 211.7 1.7 3.8e-62 210.5 0.0 2.6 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KPI41700.1 - 3.1e-06 27.3 0.3 0.053 14.1 0.4 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KPI41700.1 - 0.0086 16.3 0.1 4.5 7.6 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat WAPL PF07814.8 KPI41701.1 - 7.7e-11 41.3 5.4 1.4e-10 40.4 3.7 1.5 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin TFIID-18kDa PF02269.11 KPI41702.1 - 8.8e-15 54.2 0.0 6.6e-13 48.2 0.0 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 KPI41702.1 - 0.0046 17.0 0.0 0.0081 16.2 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KPI41702.1 - 0.018 15.0 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KPI41702.1 - 0.028 14.1 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 KPI41702.1 - 0.053 13.8 0.0 0.091 13.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A CENP-S PF15630.1 KPI41702.1 - 0.098 12.8 0.1 0.21 11.7 0.0 1.6 1 1 1 2 2 2 0 Kinetochore component CENP-S FAD_binding_3 PF01494.14 KPI41703.1 - 1.1e-17 64.1 0.0 2.6e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Abhydrolase_3 PF07859.8 KPI41703.1 - 0.00022 20.8 0.0 0.00046 19.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI41703.1 - 0.00045 20.1 0.2 0.0012 18.8 0.2 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family EXS PF03124.9 KPI41704.1 - 3.2e-101 338.8 9.7 3.7e-101 338.6 6.7 1.0 1 0 0 1 1 1 1 EXS family Sec8_exocyst PF04048.9 KPI41705.1 - 4.2e-30 104.2 0.5 3.3e-28 98.0 0.1 3.2 2 1 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KPI41705.1 - 0.00086 18.2 0.3 0.0025 16.7 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 KPI41705.1 - 0.008 15.9 0.2 0.017 14.8 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 DUF1572 PF07609.6 KPI41705.1 - 0.021 14.3 0.5 0.54 9.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1572) Vps51 PF08700.6 KPI41705.1 - 0.048 13.5 0.0 0.24 11.2 0.0 2.2 1 0 0 1 1 1 0 Vps51/Vps67 COG2 PF06148.6 KPI41705.1 - 8.9 6.1 7.2 1.4 8.7 0.3 2.8 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 KH_1 PF00013.24 KPI41706.1 - 7.4e-11 41.5 0.0 6.5e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 KPI41706.1 - 5.1e-07 29.2 0.8 0.0004 19.9 0.0 2.8 2 0 0 2 2 2 2 KH domain F-box PF00646.28 KPI41707.1 - 0.00035 20.1 0.4 0.0011 18.5 0.2 1.9 1 0 0 1 1 1 1 F-box domain Parecho_VpG PF06344.6 KPI41707.1 - 0.061 13.2 1.8 0.13 12.2 1.3 1.5 1 0 0 1 1 1 0 Parechovirus Genome-linked protein Glyco_hydro_76 PF03663.9 KPI41708.1 - 4.7e-151 503.3 14.2 5.9e-151 503.0 9.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KPI41708.1 - 0.13 11.2 4.4 0.11 11.4 0.2 2.4 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Sec34 PF04136.10 KPI41709.1 - 8.6e-26 90.5 2.1 2.2e-25 89.1 1.5 1.6 1 0 0 1 1 1 1 Sec34-like family FerA PF08165.6 KPI41709.1 - 0.023 14.3 0.2 0.078 12.6 0.1 1.9 1 0 0 1 1 1 0 FerA (NUC095) domain Spore_coat_CotO PF14153.1 KPI41709.1 - 2 7.8 7.8 0.069 12.5 1.0 1.6 2 0 0 2 2 2 0 Spore coat protein CotO FAD_binding_7 PF03441.9 KPI41710.1 - 1.7e-56 191.4 0.1 2.6e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KPI41710.1 - 2.5e-20 72.8 0.0 4.2e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase GARS_A PF01071.14 KPI41711.1 - 4.1e-83 277.7 0.0 6.9e-83 276.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.17 KPI41711.1 - 4.6e-36 124.1 0.1 1.2e-35 122.8 0.1 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.10 KPI41711.1 - 4e-32 110.6 0.1 1.6e-31 108.7 0.0 2.2 2 0 0 2 2 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 KPI41711.1 - 6.3e-27 93.5 0.1 1.6e-26 92.2 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KPI41711.1 - 3e-14 53.0 2.3 3e-14 53.0 1.6 2.7 3 0 0 3 3 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 KPI41711.1 - 1.6e-10 40.9 0.0 3.4e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 KPI41711.1 - 5e-06 25.9 0.0 1.3e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KPI41711.1 - 0.00025 19.8 0.0 0.00052 18.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 KPI41711.1 - 0.00026 20.9 0.0 0.00064 19.6 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KPI41711.1 - 0.0076 15.5 0.1 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 KPI41711.1 - 0.012 15.1 0.1 0.067 12.6 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GSH-S_ATP PF02955.11 KPI41711.1 - 0.018 14.2 0.0 0.058 12.5 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Peptidase_S11 PF00768.15 KPI41711.1 - 0.053 12.7 0.2 0.089 12.0 0.1 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase EamA PF00892.15 KPI41714.1 - 5.6e-15 55.5 22.5 4.8e-10 39.5 3.9 3.8 3 1 0 3 3 3 3 EamA-like transporter family EmrE PF13536.1 KPI41714.1 - 2.3e-06 27.7 3.7 2.3e-06 27.7 2.5 3.9 3 1 0 4 4 4 2 Multidrug resistance efflux transporter RabGAP-TBC PF00566.13 KPI41715.1 - 4.1e-32 111.4 11.2 2.9e-29 102.1 3.1 2.7 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF3548 PF12068.3 KPI41715.1 - 3.6e-06 26.4 0.0 2.3e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3548) Ferritin PF00210.19 KPI41715.1 - 0.048 13.4 0.1 0.2 11.4 0.1 2.1 1 0 0 1 1 1 0 Ferritin-like domain Carboxyl_trans PF01039.17 KPI41716.1 - 4.9e-144 480.3 0.3 5.9e-144 480.0 0.2 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Mso1_Sec1_bdg PF14475.1 KPI41717.1 - 0.054 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Sec1-binding region of Mso1 DEAD PF00270.24 KPI41719.1 - 2.1e-35 121.6 0.2 3.8e-35 120.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI41719.1 - 3.1e-24 84.6 0.0 4.6e-23 80.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI41719.1 - 3.6e-05 23.6 0.0 9.5e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TyeA PF09059.5 KPI41719.1 - 0.06 13.2 1.1 2.7 7.9 0.3 3.0 2 1 0 2 2 2 0 TyeA Cyclin PF08613.6 KPI41720.1 - 5e-12 46.4 0.0 1.3e-11 45.1 0.0 1.8 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KPI41720.1 - 0.038 13.5 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain UNC-79 PF14776.1 KPI41720.1 - 0.068 11.5 1.1 0.11 10.9 0.8 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Leu_zip PF15294.1 KPI41721.1 - 0.019 14.0 0.1 0.019 14.0 0.1 1.7 2 0 0 2 2 2 0 Leucine zipper DUF1640 PF07798.6 KPI41721.1 - 0.045 13.7 1.3 0.075 13.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Macoilin PF09726.4 KPI41721.1 - 0.047 11.9 17.0 0.064 11.5 11.8 1.1 1 0 0 1 1 1 0 Transmembrane protein CENP-F_N PF10481.4 KPI41721.1 - 0.22 10.8 11.9 2.4 7.4 8.5 2.0 1 1 0 1 1 1 0 Cenp-F N-terminal domain FlaC_arch PF05377.6 KPI41721.1 - 0.6 10.0 4.1 0.42 10.5 0.3 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HALZ PF02183.13 KPI41721.1 - 0.76 9.5 5.0 1.7 8.4 1.8 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper DegS PF05384.6 KPI41721.1 - 1.3 8.2 6.4 0.29 10.3 1.1 2.2 2 1 0 2 2 2 0 Sensor protein DegS DivIC PF04977.10 KPI41721.1 - 1.5 8.3 7.3 0.42 10.1 2.3 1.9 2 0 0 2 2 2 0 Septum formation initiator DivIVA PF05103.8 KPI41721.1 - 1.7 8.6 6.8 0.81 9.7 0.4 2.4 2 0 0 2 2 2 0 DivIVA protein DUF4345 PF14248.1 KPI41722.1 - 1.7e-17 63.0 2.3 2.1e-17 62.7 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4345) DUF1253 PF06862.7 KPI41723.1 - 2.3e-147 490.9 0.0 2.9e-147 490.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Endomucin PF07010.7 KPI41724.1 - 0.21 10.8 2.5 0.33 10.2 1.8 1.4 1 0 0 1 1 1 0 Endomucin IF-2B PF01008.12 KPI41727.1 - 3.5e-45 154.1 0.0 2.1e-21 76.1 0.1 2.1 2 0 0 2 2 2 2 Initiation factor 2 subunit family Fungal_trans_2 PF11951.3 KPI41728.1 - 2.6e-12 46.0 1.1 2.6e-12 46.0 0.8 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI41728.1 - 0.00079 19.2 9.0 0.0018 18.1 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KPI41729.1 - 3.5e-36 121.7 21.9 2.9e-12 45.9 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat MFS_1 PF07690.11 KPI41730.1 - 1.6e-41 142.2 17.8 2.4e-41 141.6 12.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Skp1 PF01466.14 KPI41731.1 - 1.4e-39 133.9 2.2 2.2e-39 133.3 1.5 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KPI41731.1 - 8.2e-22 77.0 0.0 1.9e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 KPI41731.1 - 0.0013 18.7 1.0 0.0019 18.1 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4375) BTB PF00651.26 KPI41731.1 - 0.067 13.1 0.0 0.91 9.5 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain PWI PF01480.12 KPI41732.1 - 2e-30 104.6 0.1 3.9e-30 103.7 0.1 1.5 1 0 0 1 1 1 1 PWI domain DUF3628 PF12300.3 KPI41732.1 - 0.57 10.1 14.7 1.1 9.2 10.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) Gar1 PF04410.9 KPI41732.1 - 9.4 5.6 8.2 6.1 6.2 0.1 3.0 3 0 0 3 3 3 0 Gar1/Naf1 RNA binding region cwf18 PF08315.7 KPI41733.1 - 4.5e-41 140.3 3.5 4.5e-41 140.3 2.5 2.0 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor UPF0220 PF05255.6 KPI41735.1 - 5.8e-61 204.5 1.5 6.9e-61 204.3 1.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) GATase_2 PF00310.16 KPI41736.1 - 2.7e-20 72.3 0.1 1.3e-14 53.6 0.0 3.0 2 1 0 3 3 3 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KPI41736.1 - 6e-15 55.3 0.0 1.8e-14 53.8 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KPI41736.1 - 1.4e-13 50.7 0.0 2.6e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 KPI41736.1 - 1.8e-11 43.8 0.1 3.5e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 KPI41736.1 - 2.7e-05 23.0 0.0 4.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II MFS_1 PF07690.11 KPI41737.1 - 7e-13 48.0 34.6 7e-13 48.0 24.0 2.9 1 1 1 3 3 3 2 Major Facilitator Superfamily DUF3188 PF11384.3 KPI41737.1 - 0.036 13.6 3.0 5 6.7 0.1 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) YbhQ PF11076.3 KPI41737.1 - 0.12 11.9 3.4 0.37 10.4 2.3 1.8 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ adh_short PF00106.20 KPI41738.1 - 2.6e-12 46.9 0.1 4.1e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI41738.1 - 1.3e-05 25.0 0.0 3.2e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ScdA_N PF04405.9 KPI41738.1 - 0.092 12.1 0.4 0.19 11.1 0.3 1.5 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) ETF PF01012.16 KPI41739.1 - 5.9e-40 136.6 0.2 7.4e-40 136.3 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF674 PF05056.7 KPI41739.1 - 0.11 11.1 0.1 0.19 10.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF674) PNRC PF15365.1 KPI41740.1 - 5.4e-06 26.3 1.3 5.4e-06 26.3 0.9 4.4 5 1 0 5 5 5 1 Proline-rich nuclear receptor coactivator Podoplanin PF05808.6 KPI41741.1 - 0.036 13.6 1.4 0.064 12.8 0.9 1.4 1 0 0 1 1 1 0 Podoplanin UPRTase PF14681.1 KPI41742.1 - 1.2e-80 269.5 0.0 1.5e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KPI41742.1 - 2.3e-05 24.1 0.0 3.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 KPI41742.1 - 0.11 12.2 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) CN_hydrolase PF00795.17 KPI41743.1 - 3.8e-32 111.1 0.0 4.8e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SUZ PF12752.2 KPI41744.1 - 7.8e-16 58.3 1.7 7.8e-16 58.3 1.2 4.0 4 0 0 4 4 4 1 SUZ domain R3H PF01424.17 KPI41744.1 - 2.6e-08 33.4 0.0 7.7e-08 31.9 0.0 1.9 1 0 0 1 1 1 1 R3H domain DUF4602 PF15375.1 KPI41746.1 - 5.2 7.1 9.6 1.9e+02 2.1 6.6 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4602) SDH_alpha PF03313.10 KPI41748.1 - 2.4e-68 230.2 0.3 3e-49 167.5 0.0 2.4 1 1 0 2 2 2 2 Serine dehydratase alpha chain SDH_beta PF03315.10 KPI41748.1 - 1.3e-50 171.5 0.0 2.3e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain CLPTM1 PF05602.7 KPI41749.1 - 3.3e-159 530.2 0.0 4.2e-159 529.9 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) SyrA PF11089.3 KPI41749.1 - 0.2 11.4 3.5 0.49 10.2 0.1 2.5 2 0 0 2 2 2 0 Exopolysaccharide production repressor Ribosomal_S10 PF00338.17 KPI41750.1 - 3.6e-24 84.4 0.0 7.4e-24 83.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e NST1 PF13945.1 KPI41750.1 - 0.33 10.9 6.6 0.55 10.2 4.6 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Spc7_N PF15402.1 KPI41750.1 - 1.4 6.7 15.4 1.9 6.3 10.7 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 RR_TM4-6 PF06459.7 KPI41750.1 - 1.5 8.6 5.3 2.3 8.0 3.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF566 PF04484.7 KPI41750.1 - 7 6.0 10.8 11 5.4 7.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Fes1 PF08609.5 KPI41751.1 - 1e-27 96.4 1.4 2.8e-27 95.0 1.0 1.7 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 KPI41751.1 - 7.4e-05 22.9 0.8 0.00027 21.1 0.1 2.2 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.17 KPI41751.1 - 0.011 15.7 0.1 3.6 7.9 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 KPI41751.1 - 0.012 16.0 0.5 0.082 13.4 0.1 2.6 2 1 1 3 3 3 0 HEAT-like repeat Glyco_transf_8 PF01501.15 KPI41752.1 - 5.1e-26 91.5 0.0 9.1e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KPI41752.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative ADH_N PF08240.7 KPI41753.1 - 6.6e-06 25.8 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 KPI41753.1 - 0.00042 19.8 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI41753.1 - 0.00046 20.2 0.1 0.00077 19.5 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 KPI41753.1 - 0.00066 19.2 0.1 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 KPI41753.1 - 0.0015 18.4 0.1 0.0026 17.7 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KPI41753.1 - 0.02 14.1 0.1 0.032 13.4 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family ApbA PF02558.11 KPI41753.1 - 0.1 12.0 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Chorismate_bind PF00425.13 KPI41754.1 - 5.7e-62 209.3 0.1 8.8e-32 110.4 0.0 2.2 2 0 0 2 2 2 2 chorismate binding enzyme GATase PF00117.23 KPI41754.1 - 1.9e-25 89.4 0.0 2.2e-24 85.9 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KPI41754.1 - 6.9e-15 55.2 0.0 1.6e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 KPI41754.1 - 3.2e-08 33.2 0.0 1.2e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 Sigma70_ner PF04546.8 KPI41755.1 - 0.044 13.4 2.5 0.073 12.6 1.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region ACC_epsilon PF13822.1 KPI41757.1 - 0.0076 16.5 0.7 0.0076 16.5 0.5 2.4 2 0 0 2 2 2 1 Acyl-CoA carboxylase epsilon subunit IPPT PF01715.12 KPI41758.1 - 4e-50 170.2 1.1 2.1e-29 102.2 0.6 2.5 2 1 0 2 2 2 2 IPP transferase IPT PF01745.11 KPI41758.1 - 3.7e-06 26.2 0.1 1.3e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Isopentenyl transferase zf-C2H2_jaz PF12171.3 KPI41758.1 - 5.4e-06 26.3 0.9 1.3e-05 25.1 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_33 PF13671.1 KPI41758.1 - 7.8e-06 25.8 0.1 0.0044 16.9 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KPI41758.1 - 8.7e-06 26.5 0.4 3.9e-05 24.4 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KPI41758.1 - 0.0001 22.3 0.2 0.0037 17.2 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KPI41758.1 - 0.00068 19.9 0.2 0.015 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KPI41758.1 - 0.00072 18.7 0.2 0.0042 16.1 0.0 2.3 3 0 0 3 3 3 1 Zeta toxin ABC_tran PF00005.22 KPI41758.1 - 0.00083 19.6 0.0 0.0021 18.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter zf-met PF12874.2 KPI41758.1 - 0.0012 18.9 0.8 0.0028 17.7 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_22 PF13401.1 KPI41758.1 - 0.0025 17.9 0.0 0.0058 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KPI41758.1 - 0.0042 16.5 0.0 0.0087 15.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.24 KPI41758.1 - 0.0046 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KPI41758.1 - 0.0057 16.0 0.0 0.033 13.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_PrkA PF08298.6 KPI41758.1 - 0.0062 15.2 0.0 0.0096 14.6 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain PhoH PF02562.11 KPI41758.1 - 0.0081 15.4 0.2 0.022 14.0 0.0 1.7 2 0 0 2 2 2 1 PhoH-like protein AAA_5 PF07728.9 KPI41758.1 - 0.0083 15.8 0.1 0.027 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) PPV_E1_C PF00519.12 KPI41758.1 - 0.033 12.7 0.0 0.057 12.0 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase zf-C2H2_2 PF12756.2 KPI41758.1 - 0.033 14.2 0.7 0.063 13.3 0.5 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) NACHT PF05729.7 KPI41758.1 - 0.034 13.7 0.0 0.71 9.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KPI41758.1 - 0.035 14.2 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 KPI41758.1 - 0.082 12.6 0.1 0.47 10.2 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain Arch_ATPase PF01637.13 KPI41758.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase DUF87 PF01935.12 KPI41758.1 - 0.14 11.9 0.2 0.8 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 Cupin_2 PF07883.6 KPI41759.1 - 1.6e-07 30.6 0.2 2.1e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_7 PF12973.2 KPI41759.1 - 0.022 14.5 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 ChrR Cupin-like domain PTR2 PF00854.16 KPI41760.1 - 9.6e-28 97.0 1.4 1.9e-27 96.0 0.9 1.5 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 KPI41760.1 - 1.3e-08 33.9 15.1 3e-08 32.7 10.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily CRAL_TRIO PF00650.15 KPI41761.1 - 6.3e-14 51.7 0.0 9.6e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Toxin-deaminase PF14424.1 KPI41762.1 - 0.036 14.0 0.3 0.24 11.3 0.3 2.4 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases Peptidase_A22B PF04258.8 KPI41763.1 - 1.9e-44 152.2 0.3 7.7e-44 150.3 0.2 1.9 1 1 0 1 1 1 1 Signal peptide peptidase DUF4448 PF14610.1 KPI41763.1 - 0.067 12.6 4.9 2.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Herpes_UL43 PF05072.8 KPI41763.1 - 0.092 11.4 0.0 0.092 11.4 0.0 2.6 3 0 0 3 3 3 0 Herpesvirus UL43 protein Presenilin PF01080.12 KPI41763.1 - 0.11 11.2 9.0 3.9 6.1 0.0 3.2 3 0 0 3 3 3 0 Presenilin Sigma70_ner PF04546.8 KPI41763.1 - 0.77 9.3 11.5 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region FAM176 PF14851.1 KPI41763.1 - 0.96 9.1 0.0 0.96 9.1 0.0 2.8 2 1 0 2 2 2 0 FAM176 family TRAP_alpha PF03896.11 KPI41763.1 - 2.6 6.9 13.0 0.25 10.3 0.0 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Sec62 PF03839.11 KPI41763.1 - 2.9 7.2 9.9 7.1 5.9 6.8 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 DUF1510 PF07423.6 KPI41763.1 - 4.6 6.5 18.6 13 5.0 10.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 KPI41763.1 - 8.2 6.2 13.1 0.32 10.8 4.7 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 hNIFK_binding PF12196.3 KPI41764.1 - 0.046 13.0 6.9 1 8.8 0.4 3.5 4 0 0 4 4 4 0 FHA Ki67 binding domain of hNIFK DUF506 PF04720.7 KPI41764.1 - 0.072 12.7 0.2 0.24 11.0 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF506) FAM176 PF14851.1 KPI41764.1 - 0.46 10.1 5.5 0.82 9.3 0.4 2.3 2 0 0 2 2 2 0 FAM176 family Biotin_lipoyl PF00364.17 KPI41765.1 - 5.5e-21 73.9 0.5 1e-20 73.1 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KPI41765.1 - 2.5e-06 27.0 1.2 0.00016 21.2 0.0 3.0 2 1 1 3 3 3 1 Biotin-lipoyl like HlyD_2 PF12700.2 KPI41765.1 - 0.0011 18.1 0.4 0.27 10.3 0.1 2.1 1 1 1 2 2 2 2 HlyD family secretion protein E3_binding PF02817.12 KPI41765.1 - 0.0023 17.5 0.0 0.0077 15.8 0.0 1.9 2 0 0 2 2 2 1 e3 binding domain QRPTase_N PF02749.11 KPI41765.1 - 0.13 12.0 0.0 0.5 10.2 0.0 1.9 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain GATA PF00320.22 KPI41767.1 - 1.3e-16 59.6 1.9 3.1e-16 58.4 1.3 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 KPI41767.1 - 5.3e-13 48.2 6.7 9.1e-13 47.5 4.7 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Peptidase_M24 PF00557.19 KPI41768.1 - 0.03 13.8 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase family M24 Ras PF00071.17 KPI41769.1 - 2.5e-51 173.2 0.0 2.9e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KPI41769.1 - 4.1e-20 72.4 0.0 7e-20 71.7 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KPI41769.1 - 1.5e-10 40.5 0.0 1.7e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KPI41769.1 - 7.5e-08 32.0 0.0 5.4e-06 25.9 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KPI41769.1 - 0.00046 20.1 0.0 0.00068 19.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KPI41769.1 - 0.067 13.3 0.1 0.28 11.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KPI41769.1 - 0.086 12.8 0.2 0.19 11.7 0.1 1.8 1 1 1 2 2 2 0 AAA ATPase domain An_peroxidase PF03098.10 KPI41770.1 - 1.4e-32 112.8 0.0 4.2e-31 107.9 0.0 2.3 1 1 0 1 1 1 1 Animal haem peroxidase Steroid_dh PF02544.11 KPI41771.1 - 1.6e-12 47.4 1.5 2.3e-11 43.6 1.0 2.4 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KPI41771.1 - 0.001 18.3 2.5 0.0024 17.1 1.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) IncA PF04156.9 KPI41772.1 - 3e-06 26.9 25.4 2.3e-05 24.0 5.8 5.5 1 1 4 5 5 5 3 IncA protein zf-CCCH PF00642.19 KPI41772.1 - 0.04 13.6 1.1 0.064 12.9 0.8 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Abi_C PF14355.1 KPI41772.1 - 0.26 11.2 3.8 0.73 9.8 0.1 3.2 3 0 0 3 3 3 0 Abortive infection C-terminus zf-CCCH_2 PF14608.1 KPI41772.1 - 0.88 9.6 3.0 1.4 9.0 2.1 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Myosin_tail_1 PF01576.14 KPI41772.1 - 1.3 6.6 104.2 0.75 7.4 26.4 2.7 1 1 1 2 2 2 0 Myosin tail Cast PF10174.4 KPI41772.1 - 9.6 4.1 99.7 3 5.7 17.8 3.5 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone PAP2 PF01569.16 KPI41773.1 - 4.3e-06 26.4 0.0 8.6e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily Lactamase_B_2 PF12706.2 KPI41774.1 - 9e-26 90.6 0.0 1.1e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KPI41774.1 - 8.3e-17 61.3 0.0 1.1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Erg28 PF03694.8 KPI41776.1 - 2.8e-12 46.6 3.8 3.9e-12 46.1 2.6 1.2 1 0 0 1 1 1 1 Erg28 like protein DUF4345 PF14248.1 KPI41776.1 - 0.14 11.6 2.4 0.16 11.4 1.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4345) Piwi PF02171.12 KPI41777.1 - 2.1e-70 237.0 0.1 2.9e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KPI41777.1 - 4.6e-22 77.1 0.1 9.2e-22 76.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KPI41777.1 - 5.9e-18 64.4 0.0 1e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 PAZ domain THF_DHG_CYH PF00763.18 KPI41777.1 - 0.089 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain ASF1_hist_chap PF04729.8 KPI41778.1 - 4.5e-66 221.2 0.0 7e-66 220.6 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.7 KPI41778.1 - 6 4.6 25.4 7.3 4.3 17.6 1.1 1 0 0 1 1 1 0 Nop14-like family FAD_binding_3 PF01494.14 KPI41779.1 - 1e-24 87.2 0.0 2.7e-24 85.9 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI41779.1 - 2.1e-12 46.6 0.2 1.6e-06 27.2 0.2 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KPI41779.1 - 2.5e-08 33.4 0.5 0.00021 20.4 0.2 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KPI41779.1 - 1.4e-07 31.3 0.7 4.7e-07 29.7 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KPI41779.1 - 2.3e-06 27.8 0.0 4.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI41779.1 - 2.7e-06 27.7 0.0 0.00023 21.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI41779.1 - 8.1e-06 24.9 0.0 1.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KPI41779.1 - 1.8e-05 23.7 0.4 1.8e-05 23.7 0.3 2.0 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 KPI41779.1 - 0.00051 19.9 0.4 0.0016 18.3 0.3 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KPI41779.1 - 0.00062 18.9 0.1 0.0013 17.9 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KPI41779.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.16 KPI41779.1 - 0.04 13.7 0.1 0.088 12.6 0.1 1.6 1 0 0 1 1 1 0 ThiF family Methyltransf_18 PF12847.2 KPI41779.1 - 0.083 13.4 1.0 0.27 11.8 0.3 2.4 2 1 0 2 2 2 0 Methyltransferase domain Lycopene_cycl PF05834.7 KPI41779.1 - 0.1 11.5 0.1 0.2 10.5 0.0 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 KPI41779.1 - 0.17 10.3 0.2 0.27 9.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein CBP4 PF07960.6 KPI41780.1 - 1e-27 96.2 0.2 1.2e-27 96.0 0.1 1.0 1 0 0 1 1 1 1 CBP4 NADH_B2 PF14813.1 KPI41781.1 - 0.034 13.8 0.3 0.036 13.7 0.2 1.3 1 1 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Hus1 PF04005.7 KPI41782.1 - 9.9e-92 306.9 0.0 1.1e-91 306.8 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein SIR2 PF02146.12 KPI41783.1 - 1.3e-30 106.4 0.0 1.2e-11 44.6 0.0 3.2 3 0 0 3 3 3 3 Sir2 family zf-trcl PF13451.1 KPI41783.1 - 0.029 13.9 3.2 0.061 12.9 2.2 1.5 1 0 0 1 1 1 0 Probable zinc-binding domain PALP PF00291.20 KPI41784.1 - 4e-61 206.9 0.4 5.8e-61 206.3 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Amidohydro_4 PF13147.1 KPI41784.1 - 8.7e-23 81.7 5.4 5e-21 75.9 3.8 2.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KPI41784.1 - 7e-14 52.2 0.1 2e-12 47.4 0.1 2.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KPI41784.1 - 1.4e-13 50.4 0.8 4.7e-13 48.7 0.1 2.4 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 KPI41784.1 - 6.2e-11 42.1 5.0 9.9e-08 31.6 1.1 2.7 2 1 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.15 KPI41784.1 - 0.018 15.1 0.0 0.09 12.9 0.0 2.3 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain ADH_zinc_N PF00107.21 KPI41785.1 - 1.5e-06 27.7 0.0 2.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ferritin_2 PF13668.1 KPI41785.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Ferritin-like domain Romo1 PF10247.4 KPI41786.1 - 0.0013 18.8 0.1 0.66 10.2 0.0 2.4 2 0 0 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 PNPase PF03726.9 KPI41786.1 - 0.1 12.8 1.9 0.43 10.8 0.1 2.4 2 1 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain GTP_cyclohydroI PF01227.17 KPI41787.1 - 8.4e-73 243.4 0.2 1.1e-72 243.0 0.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KPI41787.1 - 0.003 17.4 0.0 0.0063 16.4 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein Fungal_trans PF04082.13 KPI41788.1 - 1.6e-15 56.7 0.2 2.9e-15 55.8 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain MgtC PF02308.11 KPI41788.1 - 0.13 12.1 0.3 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 MgtC family DUF2229 PF09989.4 KPI41788.1 - 0.22 10.9 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Ion_trans PF00520.26 KPI41789.1 - 2.2e-06 27.0 2.9 2.2e-06 27.0 2.0 1.7 2 0 0 2 2 2 1 Ion transport protein bZIP_1 PF00170.16 KPI41789.1 - 0.00016 21.5 0.3 0.00023 21.0 0.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor HAP1_N PF04849.8 KPI41789.1 - 0.0095 14.9 0.3 0.013 14.4 0.2 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF972 PF06156.8 KPI41789.1 - 0.052 13.8 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) MFS_1 PF07690.11 KPI41790.1 - 9.8e-41 139.6 33.3 3.5e-39 134.5 16.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI41790.1 - 3.5e-13 48.9 8.6 3.5e-13 48.9 5.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 KPI41790.1 - 3.8e-07 28.7 3.6 4.3e-07 28.5 2.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KPI41790.1 - 5.6e-06 24.7 3.3 8.7e-06 24.1 2.3 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector PUCC PF03209.10 KPI41790.1 - 0.0049 15.6 17.5 0.0067 15.1 6.2 3.1 2 2 1 4 4 4 2 PUCC protein FTCD_C PF04961.7 KPI41791.1 - 0.079 12.3 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Sec6 PF06046.8 KPI41792.1 - 7.3e-127 423.8 7.9 1e-100 337.4 0.9 2.7 2 1 1 3 3 3 2 Exocyst complex component Sec6 Vps53_N PF04100.7 KPI41792.1 - 0.00034 19.5 2.8 0.00034 19.5 1.9 2.5 2 1 0 2 2 2 1 Vps53-like, N-terminal MutS_III PF05192.13 KPI41792.1 - 0.0028 17.4 1.9 0.089 12.5 1.3 2.8 1 1 0 1 1 1 1 MutS domain III Dak2 PF02734.12 KPI41792.1 - 0.0092 15.6 0.5 0.1 12.2 0.0 2.5 2 0 0 2 2 2 1 DAK2 domain LOH1CR12 PF10158.4 KPI41792.1 - 0.13 12.0 2.0 0.34 10.6 0.4 2.5 2 1 0 2 2 2 0 Tumour suppressor protein SIP1 PF04938.7 KPI41793.1 - 1.5e-05 24.4 0.3 0.00052 19.4 0.2 2.8 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Asp_Glu_race PF01177.17 KPI41794.1 - 4e-28 98.8 0.4 5.2e-28 98.4 0.3 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Fungal_trans PF04082.13 KPI41795.1 - 8e-14 51.1 0.1 1.3e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4064 PF13273.1 KPI41795.1 - 4.6 7.4 6.6 0.97 9.5 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Sugar_tr PF00083.19 KPI41796.1 - 4.3e-69 233.2 16.7 1.8e-68 231.1 11.6 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI41796.1 - 9.2e-17 60.7 17.9 9.2e-17 60.7 12.4 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI41796.1 - 3.4e-08 32.3 15.7 2.1e-07 29.7 0.2 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KPI41796.1 - 0.0034 15.6 0.2 0.0034 15.6 0.1 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Polysacc_deac_1 PF01522.16 KPI41797.1 - 2.5e-17 62.6 0.0 5.1e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase LcrG PF07216.7 KPI41799.1 - 0.45 10.5 6.8 0.53 10.3 3.4 2.1 1 1 1 2 2 2 0 LcrG protein DUF4662 PF15578.1 KPI41799.1 - 0.56 9.7 4.1 0.97 8.9 2.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4662) CD99L2 PF12301.3 KPI41799.1 - 1.5 8.4 7.0 6.3 6.4 0.7 2.1 1 1 1 2 2 2 0 CD99 antigen like protein 2 TMCO5 PF14992.1 KPI41799.1 - 1.7 7.6 8.6 2.4 7.1 5.7 1.5 1 1 0 1 1 1 0 TMCO5 family PLRV_ORF5 PF01690.12 KPI41799.1 - 1.9 7.5 8.1 2.3 7.2 5.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein FKBP_N PF01346.13 KPI41799.1 - 2.1 8.3 12.7 0.35 10.9 4.7 2.0 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Peroxin-3 PF04882.7 KPI41799.1 - 6.9 5.2 8.1 8.4 4.9 5.6 1.3 1 1 0 1 1 1 0 Peroxin-3 DNA_ligase_A_M PF01068.16 KPI41800.1 - 3.2e-22 78.8 0.0 6.2e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KPI41800.1 - 1.6e-14 54.0 0.0 3.1e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KPI41800.1 - 0.016 15.5 0.0 0.072 13.4 0.0 2.2 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region MFS_1 PF07690.11 KPI41801.1 - 1.8e-35 122.3 27.3 1.8e-35 122.3 18.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF948 PF06103.6 KPI41803.1 - 0.32 10.8 1.1 0.6 9.9 0.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PAM2 PF07145.10 KPI41803.1 - 1.5 8.4 5.7 0.72 9.4 0.5 2.8 2 0 0 2 2 2 0 Ataxin-2 C-terminal region RdRP PF05183.7 KPI41804.1 - 3.4e-158 527.9 0.0 4.5e-158 527.5 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase DIOX_N PF14226.1 KPI41805.1 - 2.4e-24 86.0 0.0 2.3e-23 82.9 0.0 2.1 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI41805.1 - 1e-18 67.4 0.0 1.9e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nop10p PF04135.7 KPI41806.1 - 1e-19 69.9 0.3 1.2e-19 69.7 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Lipase_GDSL PF00657.17 KPI41807.1 - 1.7e-15 57.5 0.0 2.5e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KPI41807.1 - 0.00012 22.2 0.3 0.00079 19.5 0.1 2.4 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.11 KPI41808.1 - 7.9e-18 64.2 16.7 1.1e-17 63.8 11.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HMG_box PF00505.14 KPI41810.1 - 7.1e-07 29.4 3.0 0.00066 19.8 0.1 2.9 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KPI41810.1 - 4.1e-05 23.8 12.0 0.002 18.4 0.3 3.2 3 0 0 3 3 3 2 HMG-box domain Kelch_3 PF13415.1 KPI41812.1 - 2.1e-09 37.3 2.3 0.0034 17.5 0.1 5.3 5 0 0 5 5 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KPI41812.1 - 4e-09 36.2 4.4 0.00036 20.5 0.1 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 KPI41812.1 - 4.2e-08 32.8 12.3 0.026 14.2 0.4 6.0 6 0 0 6 6 6 2 Galactose oxidase, central domain Herpes_gE PF02480.11 KPI41812.1 - 1.1e-05 23.9 0.0 1.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 KPI41812.1 - 0.00044 19.1 0.0 0.0007 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 KPI41812.1 - 0.0027 18.0 0.0 0.005 17.2 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Kelch_1 PF01344.20 KPI41812.1 - 0.0035 16.8 0.8 0.016 14.7 0.1 2.5 2 0 0 2 2 2 1 Kelch motif TMEM51 PF15345.1 KPI41812.1 - 0.0036 17.0 0.0 0.0065 16.1 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 Mid2 PF04478.7 KPI41812.1 - 0.0066 15.8 0.1 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.1 KPI41812.1 - 0.017 14.7 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF1517 PF07466.6 KPI41812.1 - 0.057 12.4 0.1 0.057 12.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Protocadherin PF08374.6 KPI41812.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Protocadherin LRR19-TM PF15176.1 KPI41812.1 - 0.082 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF2207 PF09972.4 KPI41812.1 - 0.12 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MSC PF09402.5 KPI41812.1 - 0.26 9.9 0.0 0.4 9.3 0.0 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain JmjC PF02373.17 KPI41813.1 - 3e-36 124.1 0.3 1.2e-35 122.1 0.2 2.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 KPI41813.1 - 1.3e-19 70.2 8.3 2.7e-19 69.1 5.8 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KPI41813.1 - 1e-18 67.2 6.9 1e-18 67.2 4.8 2.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.12 KPI41813.1 - 1.5e-06 27.5 0.0 5.6e-06 25.7 0.0 2.1 1 0 0 1 1 1 1 jmjN domain RNA_pol_Rpb2_3 PF04565.11 KPI41813.1 - 0.12 12.1 0.2 0.5 10.1 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 3 Fungal_trans PF04082.13 KPI41815.1 - 2.4e-26 92.1 0.9 4e-26 91.4 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI41815.1 - 1.5e-05 24.7 9.0 3e-05 23.8 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 KPI41816.1 - 3e-27 94.5 2.6 6.9e-27 93.3 1.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI41816.1 - 2e-24 85.5 0.2 4.3e-24 84.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Hydrolase_like PF13242.1 KPI41816.1 - 0.00021 20.9 0.0 0.018 14.7 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like DUF4453 PF14627.1 KPI41816.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) Biotin_lipoyl PF00364.17 KPI41816.1 - 0.076 12.6 0.2 0.26 10.9 0.1 1.8 1 0 0 1 1 1 0 Biotin-requiring enzyme DHHA2 PF02833.9 KPI41817.1 - 5.3e-12 46.0 0.0 9.5e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 KPI41817.1 - 4.6e-08 32.8 0.0 9.7e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 DHH family AA_permease_2 PF13520.1 KPI41818.1 - 2.4e-52 177.9 49.6 2.9e-52 177.6 34.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI41818.1 - 4.3e-22 78.1 39.2 5.6e-22 77.7 27.2 1.0 1 0 0 1 1 1 1 Amino acid permease EF-hand_4 PF12763.2 KPI41820.1 - 2.6e-35 120.3 0.0 1.9e-14 53.2 0.0 3.7 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KPI41820.1 - 1e-10 41.5 0.0 3.5e-06 27.0 0.0 3.9 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.27 KPI41820.1 - 3.7e-09 35.2 0.1 0.16 11.3 0.1 4.7 4 0 0 4 4 4 2 EF hand UBA PF00627.26 KPI41820.1 - 4e-05 23.3 0.0 8.6e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.1 KPI41820.1 - 0.0001 21.8 0.7 3.1 7.9 0.0 4.5 4 0 0 4 4 4 1 EF-hand domain MbeD_MobD PF04899.7 KPI41820.1 - 0.0002 21.1 15.7 0.0011 18.8 2.8 3.6 3 1 1 4 4 3 2 MbeD/MobD like EF-hand_8 PF13833.1 KPI41820.1 - 0.00098 18.6 0.0 1.2 8.7 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain pair Reo_sigmaC PF04582.7 KPI41820.1 - 0.029 13.5 9.2 0.034 13.3 1.7 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 KPI41820.1 - 0.031 14.1 30.6 0.021 14.7 12.4 3.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 KPI41820.1 - 0.066 10.5 35.9 0.13 9.5 24.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 KPI41820.1 - 0.083 10.6 37.1 0.031 12.0 4.2 2.2 1 1 1 2 2 2 0 Myosin tail Spc7 PF08317.6 KPI41820.1 - 0.19 10.3 29.1 0.17 10.5 2.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.1 KPI41820.1 - 0.59 8.5 23.0 1.2 7.5 16.0 1.5 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 KPI41820.1 - 0.77 8.9 29.8 0.086 12.0 9.3 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 KPI41820.1 - 0.8 9.4 33.2 2.4 7.8 16.1 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 KPI41820.1 - 0.95 9.2 35.3 0.11 12.2 5.3 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Occludin_ELL PF07303.8 KPI41820.1 - 1 10.1 17.1 4.9 7.9 4.1 3.3 3 1 1 4 4 4 0 Occludin homology domain IFT57 PF10498.4 KPI41820.1 - 1.4 7.6 18.5 3.3 6.3 12.8 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Macoilin PF09726.4 KPI41820.1 - 3 6.0 32.5 3.6 5.7 2.3 2.2 1 1 1 2 2 2 0 Transmembrane protein DUF1664 PF07889.7 KPI41820.1 - 4.1 7.2 13.5 0.18 11.5 1.6 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Filament PF00038.16 KPI41820.1 - 7.6 5.8 31.1 0.41 10.0 4.0 2.1 1 1 0 1 1 1 0 Intermediate filament protein APG6 PF04111.7 KPI41820.1 - 7.7 5.4 33.7 0.14 11.1 10.4 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Atg14 PF10186.4 KPI41820.1 - 9.2 5.1 30.6 2 7.2 10.3 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Phosphodiest PF01663.17 KPI41822.1 - 9.7e-27 94.2 0.0 1.2e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KPI41822.1 - 0.017 14.3 0.0 0.26 10.4 0.0 2.1 2 0 0 2 2 2 0 Sulfatase Methyltransf_3 PF01596.12 KPI41823.1 - 1.6e-13 50.2 0.0 2.2e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KPI41823.1 - 8e-10 39.5 0.0 1.4e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 KPI41823.1 - 0.024 13.9 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 Cephalosporin hydroxylase POT1 PF02765.12 KPI41824.1 - 1.7e-07 31.2 0.0 2.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Cons_hypoth698 PF03601.9 KPI41824.1 - 0.67 8.5 0.0 1.1 7.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 698 p450 PF00067.17 KPI41825.1 - 1.2e-50 172.3 0.0 3e-50 171.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 KPI41826.1 - 4.1e-34 117.6 0.0 5.5e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme SIS_2 PF13580.1 KPI41826.1 - 0.086 12.5 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 SIS domain PDZ_2 PF13180.1 KPI41826.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Fungal_trans PF04082.13 KPI41827.1 - 7.3e-25 87.3 2.2 1.4e-24 86.4 1.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2722 PF10846.3 KPI41827.1 - 0.014 14.4 0.8 0.024 13.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pkinase PF00069.20 KPI41828.1 - 3.6e-54 183.6 0.1 1.6e-37 129.0 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KPI41828.1 - 8e-26 90.6 0.2 1.2e-18 67.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KPI41828.1 - 3e-05 23.1 0.1 0.00014 20.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KPI41828.1 - 0.0006 18.9 0.0 0.0014 17.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 KPI41828.1 - 0.0042 17.5 0.3 0.017 15.6 0.0 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain APH PF01636.18 KPI41828.1 - 0.0063 16.2 0.8 0.12 12.0 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KPI41828.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Mito_carr PF00153.22 KPI41829.1 - 2.7e-53 177.6 2.0 7e-19 67.3 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_114 PF03537.8 KPI41830.1 - 1e-26 92.4 0.1 2e-26 91.5 0.1 1.5 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Yae1_N PF09811.4 KPI41830.1 - 0.014 14.8 2.7 0.02 14.3 0.5 2.1 2 0 0 2 2 2 0 Essential protein Yae1, N terminal SPC22 PF04573.7 KPI41831.1 - 1.1e-37 128.9 0.0 7.6e-27 93.6 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit Pas_Saposin PF09016.5 KPI41831.1 - 0.021 14.7 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Pas factor saposin fold Rad9_Rad53_bind PF08605.5 KPI41832.1 - 4.3e-20 71.8 0.0 7.2e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 KPI41832.1 - 1.6e-07 31.3 0.0 3.5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Oxidored_nitro PF00148.14 KPI41832.1 - 0.062 11.9 0.2 0.11 11.1 0.2 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Lactamase_B PF00753.22 KPI41833.1 - 0.00015 21.5 0.1 0.00029 20.5 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI41833.1 - 0.00077 19.0 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Mito_carr PF00153.22 KPI41834.1 - 4.9e-27 93.4 6.3 2.4e-11 43.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1388 PF07142.7 KPI41835.1 - 0.81 9.4 3.3 0.27 11.0 0.4 1.5 2 0 0 2 2 2 0 Repeat of unknown function (DUF1388) RRM_1 PF00076.17 KPI41836.1 - 6.5e-56 185.8 0.0 1.1e-15 57.0 0.0 5.6 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI41836.1 - 5.2e-38 128.8 0.0 1.9e-10 40.5 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI41836.1 - 3.5e-11 42.7 0.0 0.00075 19.2 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spheroidin PF05541.7 KPI41836.1 - 0.017 12.7 0.0 0.024 12.2 0.0 1.1 1 0 0 1 1 1 0 Entomopoxvirus spheroidin protein Ribosomal_L2_C PF03947.13 KPI41838.1 - 2.3e-46 156.7 0.4 1.4e-35 121.9 0.3 2.4 2 0 0 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KPI41838.1 - 5.2e-26 90.4 0.5 9.1e-26 89.6 0.3 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain FAD_binding_3 PF01494.14 KPI41839.1 - 9.2e-54 182.8 0.0 1.6e-53 182.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KPI41839.1 - 0.004 16.7 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Sugar_tr PF00083.19 KPI41840.1 - 1.2e-70 238.4 27.8 1.3e-70 238.1 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI41840.1 - 6.4e-09 34.9 15.4 6.4e-09 34.9 10.7 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KPI41840.1 - 3.6e-07 28.9 19.7 6.3e-05 21.5 5.0 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein UNC-93 PF05978.11 KPI41840.1 - 0.007 15.8 2.8 0.007 15.8 1.9 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 SGL PF08450.7 KPI41841.1 - 0.011 15.0 0.1 0.26 10.6 0.0 2.5 3 0 0 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region adh_short PF00106.20 KPI41842.1 - 2.9e-12 46.8 0.2 4.9e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI41842.1 - 3.4e-06 26.8 0.1 6.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KPI41842.1 - 0.00055 19.0 0.1 0.00099 18.1 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short_C2 PF13561.1 KPI41842.1 - 0.0022 17.8 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 KPI41842.1 - 0.0036 16.9 0.1 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KPI41842.1 - 0.015 15.3 0.4 0.073 13.0 0.3 2.2 1 1 0 1 1 1 0 NADH(P)-binding UPF0146 PF03686.8 KPI41842.1 - 0.048 13.4 0.2 0.33 10.7 0.1 2.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0146) VWA_3 PF13768.1 KPI41842.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain ADH_N PF08240.7 KPI41843.1 - 8e-31 106.0 0.8 1.5e-30 105.1 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI41843.1 - 4.3e-20 71.5 0.4 6.6e-20 70.9 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI41843.1 - 4.2e-09 37.3 0.0 9.1e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KPI41843.1 - 0.0044 16.6 0.1 0.0069 15.9 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SKIP_SNW PF02731.10 KPI41844.1 - 5.7e-67 224.0 6.1 5.7e-67 224.0 4.3 2.4 2 0 0 2 2 2 1 SKIP/SNW domain p450 PF00067.17 KPI41845.1 - 2e-51 175.0 0.0 2.7e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Podoplanin PF05808.6 KPI41846.1 - 0.00091 18.8 0.4 0.0017 17.9 0.2 1.4 1 0 0 1 1 1 1 Podoplanin DUF2668 PF10873.3 KPI41846.1 - 0.0094 16.1 0.2 0.0094 16.1 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2668) VSP PF03302.8 KPI41846.1 - 0.025 13.2 1.7 0.036 12.6 1.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Rab5ip PF07019.7 KPI41846.1 - 4.9 7.3 5.9 9.9 6.3 4.1 1.4 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) DUF4117 PF13491.1 KPI41846.1 - 8.5 5.7 8.7 16 4.9 5.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4117) DAGK_cat PF00781.19 KPI41847.1 - 1.2e-23 83.0 0.0 2e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NmrA PF05368.8 KPI41848.1 - 8.4e-06 25.1 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family AA_permease PF00324.16 KPI41849.1 - 1.2e-104 350.3 44.4 2.8e-104 349.1 30.8 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI41849.1 - 1.1e-24 86.7 44.4 2.3e-22 79.1 30.7 2.0 1 1 0 1 1 1 1 Amino acid permease FlgN PF05130.7 KPI41850.1 - 0.011 16.0 0.2 0.012 15.9 0.1 1.1 1 0 0 1 1 1 0 FlgN protein WD40 PF00400.27 KPI41851.1 - 1.6e-32 110.1 7.9 2.5e-09 36.6 0.2 6.1 5 1 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KPI41851.1 - 3.7e-05 23.3 0.1 0.00085 18.8 0.0 2.2 2 0 0 2 2 2 1 PQQ-like domain CLTH PF10607.4 KPI41851.1 - 0.0014 18.3 0.4 0.0022 17.6 0.3 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Nbas_N PF15492.1 KPI41851.1 - 0.018 14.1 0.0 0.55 9.2 0.0 2.3 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 KPI41851.1 - 0.027 14.1 0.6 7.9 6.2 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat SGL PF08450.7 KPI41851.1 - 0.041 13.2 0.0 2.2 7.5 0.0 2.8 2 1 1 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region DUF4221 PF13970.1 KPI41851.1 - 0.048 12.9 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) eIF2A PF08662.6 KPI41851.1 - 0.14 11.8 0.2 3.8 7.1 0.1 2.9 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PUF PF00806.14 KPI41853.1 - 1.7e-58 190.8 8.0 4.1e-09 35.4 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat GlutR_dimer PF00745.15 KPI41853.1 - 0.1 12.5 0.1 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain p450 PF00067.17 KPI41854.1 - 4.5e-63 213.3 0.0 5.9e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 KPI41855.1 - 1.6e-05 24.9 0.4 0.00037 20.4 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI41855.1 - 0.00041 19.9 0.0 0.0007 19.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Aldolase_II PF00596.16 KPI41856.1 - 5.3e-50 169.5 0.7 7.5e-50 169.0 0.5 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MAT1 PF06391.8 KPI41858.1 - 0.037 13.6 1.3 0.068 12.7 0.9 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 MFS_1 PF07690.11 KPI41859.1 - 9.4e-26 90.3 34.6 1.5e-25 89.7 24.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3180 PF11377.3 KPI41859.1 - 1.8 8.4 7.9 4.2 7.2 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) Aminotran_5 PF00266.14 KPI41860.1 - 1.2e-22 80.1 0.0 1.5e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Pkinase PF00069.20 KPI41862.1 - 1.8e-07 30.5 0.0 3e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Transp_cyt_pur PF02133.10 KPI41863.1 - 6.7e-96 321.5 38.1 7.6e-96 321.3 26.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin 2-Hacid_dh_C PF02826.14 KPI41867.1 - 1.5e-57 193.6 0.0 1.9e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KPI41867.1 - 3.3e-19 68.6 0.0 3.7e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KPI41867.1 - 1.2e-07 31.6 0.0 4.8e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KPI41867.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 KPI41867.1 - 0.047 14.1 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Gp_dh_N PF00044.19 KPI41867.1 - 0.047 13.6 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain MFS_1 PF07690.11 KPI41868.1 - 1.1e-14 53.9 24.9 8.6e-13 47.7 17.3 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4357 PF14267.1 KPI41868.1 - 0.058 13.0 0.1 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) CPDase PF07823.6 KPI41869.1 - 3.5e-33 114.7 0.0 4e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 KPI41869.1 - 0.0025 17.5 0.0 0.099 12.3 0.1 2.1 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily NAAA-beta PF15508.1 KPI41870.1 - 3.8e-19 68.8 0.0 5.7e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase MgtC PF02308.11 KPI41870.1 - 0.066 13.0 0.1 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 MgtC family p450 PF00067.17 KPI41872.1 - 2.5e-50 171.3 0.0 3.3e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Baculo_PEP_C PF04513.7 KPI41873.1 - 0.00011 22.0 10.1 0.0016 18.3 6.9 2.4 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus zf-ZPR1 PF03367.8 KPI41873.1 - 0.0095 15.1 4.7 0.63 9.1 0.1 3.1 1 1 2 4 4 4 2 ZPR1 zinc-finger domain GFO_IDH_MocA PF01408.17 KPI41874.1 - 1.9e-16 60.6 0.3 4e-16 59.6 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KPI41874.1 - 5.3e-09 35.8 0.0 1.4e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Lipocalin_2 PF08212.7 KPI41874.1 - 2.4e-07 30.6 0.0 4.2e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Lipocalin-like domain B12-binding PF02310.14 KPI41874.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain TPR_14 PF13428.1 KPI41875.1 - 1e-24 84.7 29.7 0.0014 19.0 0.0 12.3 7 3 6 13 13 13 7 Tetratricopeptide repeat TPR_19 PF14559.1 KPI41875.1 - 1.4e-24 86.2 7.6 2.6e-05 24.4 0.0 7.9 8 0 0 8 8 7 4 Tetratricopeptide repeat HAT PF02184.11 KPI41875.1 - 2.7e-23 81.4 81.3 2.3e-15 56.0 2.6 13.5 14 0 0 14 14 14 5 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 KPI41875.1 - 7.8e-21 74.2 21.3 0.0049 17.5 0.0 9.4 9 1 0 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 KPI41875.1 - 4e-11 42.6 16.8 0.0086 15.9 0.0 9.2 10 0 0 10 10 10 2 Tetratricopeptide repeat Suf PF05843.9 KPI41875.1 - 6.7e-10 39.1 25.5 0.0072 16.0 1.3 6.7 2 1 3 6 6 6 4 Suppressor of forked protein (Suf) TPR_11 PF13414.1 KPI41875.1 - 4.4e-09 35.8 15.8 0.12 12.0 0.0 7.2 8 0 0 8 8 8 4 TPR repeat TPR_2 PF07719.12 KPI41875.1 - 7.2e-09 34.9 28.1 0.32 11.0 0.0 10.2 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 KPI41875.1 - 6.9e-07 28.9 11.4 0.071 13.3 0.0 6.9 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KPI41875.1 - 9.2e-06 25.0 17.9 2.8 7.9 0.0 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 KPI41875.1 - 2.1e-05 24.6 32.4 0.99 10.0 0.0 9.7 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_15 PF13429.1 KPI41875.1 - 2.6e-05 23.4 22.0 0.0051 15.9 3.0 5.9 2 2 1 5 5 5 3 Tetratricopeptide repeat U3_assoc_6 PF08640.6 KPI41875.1 - 0.00053 19.6 28.2 0.024 14.4 1.9 7.2 4 3 3 7 7 7 1 U3 small nucleolar RNA-associated protein 6 RAB3GAP2_C PF14656.1 KPI41875.1 - 0.0018 16.4 0.0 0.0029 15.8 0.0 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus TPR_8 PF13181.1 KPI41875.1 - 0.0035 16.9 17.2 8.4 6.4 0.0 7.9 9 0 0 9 9 9 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KPI41875.1 - 0.073 12.9 18.4 2.3 8.1 0.8 6.9 8 0 0 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 KPI41875.1 - 0.53 9.9 14.8 33 4.3 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat HATPase_c PF02518.21 KPI41876.1 - 1.5e-22 79.4 0.1 2.9e-22 78.4 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KPI41876.1 - 2e-16 59.9 0.0 4.7e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KPI41876.1 - 1.1e-13 50.9 0.0 3.8e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Sugar_tr PF00083.19 KPI41877.1 - 6.1e-71 239.3 22.9 7e-71 239.1 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI41877.1 - 5.7e-23 81.1 26.6 5.7e-23 81.1 18.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TraP PF07296.6 KPI41877.1 - 0.011 14.6 0.8 0.26 10.2 0.0 2.2 2 0 0 2 2 2 0 TraP protein PDR_assoc PF08370.6 KPI41877.1 - 0.071 12.6 2.2 0.11 12.0 0.1 2.5 2 0 0 2 2 2 0 Plant PDR ABC transporter associated MFS_2 PF13347.1 KPI41877.1 - 0.23 9.8 34.2 0.0077 14.6 3.8 3.5 2 1 1 3 3 3 0 MFS/sugar transport protein QRPTase_C PF01729.14 KPI41880.1 - 2.5e-55 186.5 0.0 3.9e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 KPI41880.1 - 1.9e-23 82.0 0.0 5.6e-23 80.5 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRAI PF00697.17 KPI41880.1 - 0.031 13.8 0.1 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase IGPS PF00218.16 KPI41880.1 - 0.049 12.6 0.0 0.13 11.3 0.1 1.6 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase PHB_depo_C PF06850.6 KPI41880.1 - 0.051 12.7 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 PHB de-polymerase C-terminus Acyl_transf_1 PF00698.16 KPI41881.1 - 3.4e-12 46.3 0.0 3.7e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain DUF1439 PF07273.7 KPI41881.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1439) Adaptin_N PF01602.15 KPI41882.1 - 1.8e-93 313.6 6.3 3.1e-93 312.8 4.4 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 KPI41882.1 - 2.5e-61 205.1 0.0 9.3e-61 203.2 0.0 2.0 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 KPI41882.1 - 3.1e-61 205.1 0.5 8.2e-61 203.7 0.4 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 KPI41882.1 - 1.9e-12 47.2 11.0 2.9e-09 37.0 0.1 4.7 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 KPI41882.1 - 2.5e-05 24.2 6.5 0.069 12.9 0.0 4.3 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KPI41882.1 - 0.00013 21.7 0.2 0.053 13.6 0.1 4.0 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 KPI41882.1 - 0.00047 20.5 2.7 0.025 15.0 0.2 4.2 2 1 1 3 3 3 2 HEAT-like repeat HEAT_PBS PF03130.11 KPI41882.1 - 0.013 15.9 0.7 21 5.9 0.0 4.0 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Arm PF00514.18 KPI41882.1 - 0.068 13.0 1.8 1.1 9.1 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat SelB-wing_1 PF09105.5 KPI41883.1 - 0.017 14.7 0.1 0.045 13.4 0.1 1.7 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Cu_bind_like PF02298.12 KPI41884.1 - 0.00051 19.7 0.0 0.00097 18.8 0.0 1.5 1 1 0 1 1 1 1 Plastocyanin-like domain Cupredoxin_1 PF13473.1 KPI41884.1 - 0.022 14.6 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Cupredoxin-like domain DUF3597 PF12200.3 KPI41884.1 - 0.65 10.3 3.4 15 6.0 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Cyclase PF04199.8 KPI41885.1 - 7.9e-07 28.9 0.1 1.1e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.7 KPI41885.1 - 0.0081 15.5 0.1 0.026 13.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF861) HMG_box PF00505.14 KPI41885.1 - 0.015 15.5 0.2 0.036 14.3 0.1 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box Cyt-b5 PF00173.23 KPI41886.1 - 9.4e-13 47.7 0.0 1.2e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4319 PF14203.1 KPI41887.1 - 0.19 11.3 1.4 0.3 10.6 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) CN_hydrolase PF00795.17 KPI41888.1 - 3.4e-27 94.9 0.0 5.2e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 KPI41888.1 - 3.5e-18 65.3 0.0 3.8e-17 61.9 0.0 2.1 1 1 0 1 1 1 1 NAD synthase DUF4148 PF13663.1 KPI41888.1 - 0.053 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Asn_synthase PF00733.16 KPI41888.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 1 0 1 1 1 0 Asparagine synthase SNF2_N PF00176.18 KPI41889.1 - 3e-51 173.9 0.9 5.4e-51 173.1 0.1 1.9 2 1 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.19 KPI41889.1 - 8e-21 73.4 10.8 7.7e-14 51.1 2.2 3.1 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KPI41889.1 - 5.4e-13 48.5 0.0 1.7e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 KPI41889.1 - 5e-12 45.9 0.0 4.3e-11 42.9 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) ECH PF00378.15 KPI41890.1 - 5e-40 137.1 0.1 1e-39 136.1 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family HMGL-like PF00682.14 KPI41890.1 - 3.7e-36 124.9 0.0 8.7e-36 123.7 0.0 1.6 2 0 0 2 2 2 1 HMGL-like EMP24_GP25L PF01105.19 KPI41891.1 - 7.2e-45 152.9 1.5 8.3e-45 152.7 1.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD tRNA_int_endo PF01974.12 KPI41892.1 - 3.6e-21 74.7 0.0 8.6e-21 73.5 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 KPI41892.1 - 4.3e-06 26.1 0.1 0.0015 18.0 0.1 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Sugar_tr PF00083.19 KPI41893.1 - 1.5e-106 356.7 22.3 1.8e-106 356.4 15.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI41893.1 - 6.1e-25 87.6 27.1 6.1e-25 87.6 18.8 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KPI41893.1 - 2.3e-08 32.7 6.5 4.1e-08 31.8 4.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KPI41893.1 - 0.00056 19.6 0.6 0.0036 17.0 0.1 2.7 2 0 0 2 2 2 1 MFS_1 like family LacY_symp PF01306.14 KPI41893.1 - 0.0076 14.8 4.7 0.02 13.4 0.8 2.3 2 0 0 2 2 2 1 LacY proton/sugar symporter FimP PF09766.4 KPI41894.1 - 7.7 5.4 14.4 14 4.5 10.0 1.4 1 0 0 1 1 1 0 Fms-interacting protein Glyco_hydro_43 PF04616.9 KPI41895.1 - 1.7e-86 289.9 2.8 8.3e-65 218.6 0.7 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 PhyH PF05721.8 KPI41896.1 - 8.7e-24 84.7 0.1 1.3e-23 84.1 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Abhydrolase_4 PF08386.5 KPI41897.1 - 3.9e-13 49.1 0.0 8.1e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KPI41897.1 - 4.7e-13 49.2 0.0 9.4e-13 48.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI41897.1 - 2.8e-09 37.2 0.2 2.5e-08 34.0 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI41897.1 - 0.014 15.1 0.0 0.34 10.6 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF4078 PF13300.1 KPI41898.1 - 1.4e-28 98.7 13.6 1.4e-28 98.7 9.4 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4078) Sugar_tr PF00083.19 KPI41899.1 - 4.9e-67 226.4 14.1 1.4e-41 142.5 0.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI41899.1 - 9.2e-19 67.3 45.1 1.9e-17 63.0 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro_racemase PF05544.6 KPI41900.1 - 2.9e-55 187.3 0.0 1.7e-54 184.8 0.0 2.0 1 1 0 1 1 1 1 Proline racemase MARVEL PF01284.18 KPI41901.1 - 2.6e-16 59.7 8.9 3.8e-16 59.2 6.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain CD20 PF04103.10 KPI41901.1 - 0.016 15.1 0.2 0.039 13.8 0.2 1.6 1 0 0 1 1 1 0 CD20-like family Myb_DNA-bind_6 PF13921.1 KPI41902.1 - 0.00022 21.2 0.1 0.0021 18.1 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Ribosomal_60s PF00428.14 KPI41903.1 - 0.071 13.5 0.3 0.071 13.5 0.2 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein AAA PF00004.24 KPI41904.1 - 1.9e-14 54.0 0.0 5.6e-14 52.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 KPI41904.1 - 1.2e-05 24.9 0.2 4e-05 23.3 0.2 1.8 1 1 0 1 1 1 1 BCS1 N terminal AAA_17 PF13207.1 KPI41904.1 - 0.00015 22.5 0.0 0.00036 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain CENP-B_dimeris PF09026.5 KPI41904.1 - 0.003 17.7 0.8 0.089 13.0 0.3 2.3 2 0 0 2 2 2 1 Centromere protein B dimerisation domain AAA_25 PF13481.1 KPI41904.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 KPI41904.1 - 0.014 14.5 0.8 0.72 9.0 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 KPI41904.1 - 0.02 14.7 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KPI41904.1 - 0.034 13.8 0.0 0.081 12.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 KPI41904.1 - 0.036 14.0 0.2 0.14 12.1 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 KPI41904.1 - 0.041 14.1 0.4 0.24 11.6 0.0 2.6 2 1 0 2 2 2 0 ABC transporter IstB_IS21 PF01695.12 KPI41904.1 - 0.047 13.0 0.1 0.19 11.1 0.0 1.8 1 1 1 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.1 KPI41904.1 - 0.066 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TIP49 PF06068.8 KPI41904.1 - 0.072 11.7 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus ANF_receptor PF01094.23 KPI41904.1 - 0.16 10.7 0.0 0.27 9.9 0.0 1.3 1 0 0 1 1 1 0 Receptor family ligand binding region Methyltransf_2 PF00891.13 KPI41905.1 - 2.2e-11 43.4 0.0 9.2e-11 41.3 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase CN_hydrolase PF00795.17 KPI41906.1 - 1.5e-20 73.3 0.0 8e-20 70.9 0.0 1.9 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Pkinase PF00069.20 KPI41907.1 - 2.8e-08 33.2 0.0 6e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain CDC27 PF09507.5 KPI41907.1 - 6.2 5.9 14.7 9.5 5.3 10.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DIT1_PvcA PF05141.7 KPI41908.1 - 2.1e-67 227.3 0.3 1.4e-65 221.3 0.2 2.1 1 1 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein Asparaginase_2 PF01112.13 KPI41908.1 - 0.2 10.3 0.3 0.3 9.7 0.2 1.2 1 0 0 1 1 1 0 Asparaginase MFS_1 PF07690.11 KPI41909.1 - 1.8e-37 128.9 38.3 1.8e-37 128.9 26.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Acyl_transf_3 PF01757.17 KPI41909.1 - 1.2 7.8 38.5 0.012 14.4 13.4 2.4 2 1 0 2 2 2 0 Acyltransferase family DUF1228 PF06779.9 KPI41909.1 - 6.9 6.7 12.1 0.98 9.4 2.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) MR_MLE_C PF13378.1 KPI41910.1 - 2.6e-13 49.9 0.0 6e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KPI41910.1 - 4e-13 49.6 0.0 9.2e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KPI41910.1 - 1.6e-06 28.0 0.0 3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain ANTAR PF03861.9 KPI41910.1 - 0.073 12.6 0.1 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 ANTAR domain FAD_binding_3 PF01494.14 KPI41911.1 - 1.6e-21 76.7 0.8 6.7e-21 74.7 0.6 1.8 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KPI41911.1 - 1.9e-05 23.9 1.6 0.00078 18.6 0.0 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KPI41911.1 - 0.00019 21.3 0.3 0.00066 19.6 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI41911.1 - 0.00062 18.7 6.4 0.092 11.6 3.4 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI41911.1 - 0.005 16.7 0.6 0.013 15.4 0.4 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI41911.1 - 0.0077 15.1 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 KPI41911.1 - 0.037 12.8 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_3 PF13738.1 KPI41911.1 - 0.11 12.5 0.6 0.46 10.5 0.4 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI41911.1 - 0.12 11.3 0.9 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 KPI41911.1 - 0.18 11.5 1.1 0.34 10.6 0.7 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 KPI41911.1 - 0.35 10.6 4.0 11 5.8 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KPI41911.1 - 0.53 9.9 2.8 1 8.9 1.9 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KPI41911.1 - 0.61 8.4 2.8 1.3 7.4 1.9 1.6 1 1 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 KPI41911.1 - 0.86 10.0 5.5 1.7 9.1 2.5 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase COesterase PF00135.23 KPI41912.1 - 1.6e-67 228.4 0.0 3e-67 227.5 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI41912.1 - 3e-08 33.4 1.9 0.00023 20.8 0.0 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI41912.1 - 1.4e-06 27.7 0.0 3.6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 KPI41912.1 - 0.00051 19.5 0.2 0.0012 18.2 0.1 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KPI41912.1 - 0.0019 17.9 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KPI41912.1 - 0.051 12.1 0.0 2 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Pkinase PF00069.20 KPI41913.1 - 7.8e-51 172.7 0.0 5.2e-45 153.6 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KPI41913.1 - 8e-28 97.2 0.0 5e-26 91.3 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KPI41913.1 - 0.00056 19.7 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KPI41913.1 - 0.0057 15.6 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KPI41913.1 - 0.023 13.5 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 ATP-synt_ab PF00006.20 KPI41915.1 - 6.8e-73 244.7 0.0 4.7e-53 179.8 0.0 2.3 1 1 1 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KPI41915.1 - 2.2e-19 70.0 0.8 4e-19 69.1 0.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KPI41915.1 - 4e-14 52.5 0.4 8.1e-14 51.5 0.3 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Topoisom_bac PF01131.15 KPI41916.1 - 3.8e-81 272.9 0.0 5.5e-81 272.4 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 KPI41916.1 - 1.8e-20 72.7 0.0 1.4e-19 69.9 0.0 2.2 2 0 0 2 2 2 1 Toprim domain RNA_pol_Rpb2_6 PF00562.23 KPI41917.1 - 5.2e-119 397.4 0.1 7.6e-119 396.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KPI41917.1 - 7.7e-47 158.8 0.2 1.5e-46 157.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KPI41917.1 - 3.9e-27 94.9 0.3 8.6e-27 93.7 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KPI41917.1 - 1.9e-23 82.4 0.8 4.3e-23 81.3 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KPI41917.1 - 5.1e-21 74.2 0.0 1.2e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KPI41917.1 - 5e-18 64.6 0.0 9.7e-18 63.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KPI41917.1 - 1.2e-11 44.3 0.2 2.6e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 adh_short PF00106.20 KPI41918.1 - 2e-14 53.8 0.2 2.6e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI41918.1 - 8.6e-11 42.0 0.3 1.1e-10 41.6 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI41918.1 - 1.5e-06 27.9 0.4 1.9e-06 27.6 0.3 1.1 1 0 0 1 1 1 1 KR domain ABC_tran PF00005.22 KPI41919.1 - 7.4e-36 123.4 0.0 1.1e-17 64.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KPI41919.1 - 6.6e-14 52.5 8.2 0.0012 18.8 0.6 4.5 3 2 0 4 4 3 3 AAA domain SMC_N PF02463.14 KPI41919.1 - 1.9e-12 46.8 1.3 0.00092 18.4 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KPI41919.1 - 6.6e-09 35.3 0.1 0.17 10.8 0.1 4.2 4 0 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 KPI41919.1 - 1.9e-06 28.6 0.2 0.02 15.7 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 KPI41919.1 - 6.6e-06 26.3 0.0 0.015 15.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KPI41919.1 - 2.3e-05 24.6 0.2 0.38 11.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KPI41919.1 - 7.3e-05 22.2 0.6 0.056 12.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KPI41919.1 - 0.0001 22.4 0.0 0.028 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KPI41919.1 - 0.00012 21.2 0.0 0.46 9.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KPI41919.1 - 0.0005 20.5 0.1 0.1 13.1 0.0 3.2 3 0 0 3 3 3 1 Miro-like protein AAA_16 PF13191.1 KPI41919.1 - 0.00061 19.8 0.2 0.31 10.9 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KPI41919.1 - 0.00079 19.3 0.3 0.2 11.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain VirE PF05272.6 KPI41919.1 - 0.0011 18.4 0.1 1.3 8.4 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E RNA_helicase PF00910.17 KPI41919.1 - 0.0018 18.4 0.1 0.83 9.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Thymidylate_kin PF02223.12 KPI41919.1 - 0.002 17.5 0.8 0.97 8.7 0.0 3.1 3 0 0 3 3 3 1 Thymidylate kinase Rad17 PF03215.10 KPI41919.1 - 0.0022 16.7 0.0 0.066 11.8 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein MobB PF03205.9 KPI41919.1 - 0.0029 17.3 1.1 0.42 10.3 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 KPI41919.1 - 0.0033 17.0 0.1 0.059 13.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 KPI41919.1 - 0.0039 16.6 0.1 2.6 7.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.1 KPI41919.1 - 0.0041 15.6 0.0 0.0041 15.6 0.0 2.6 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 KPI41919.1 - 0.0054 17.0 1.4 0.26 11.6 0.4 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KPI41919.1 - 0.0067 16.4 0.9 0.66 9.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.17 KPI41919.1 - 0.0075 15.7 3.3 0.14 11.6 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.7 KPI41919.1 - 0.011 15.3 1.9 1.1 8.8 0.0 2.6 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 KPI41919.1 - 0.025 13.4 0.1 2.5 6.8 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain SbcCD_C PF13558.1 KPI41919.1 - 0.035 14.0 0.1 8.2 6.4 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RLI PF04068.10 KPI41919.1 - 0.036 13.6 0.0 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_14 PF13173.1 KPI41919.1 - 0.051 13.4 1.0 7.6 6.4 0.1 3.2 2 2 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KPI41919.1 - 0.053 13.2 0.5 2.6 7.7 0.1 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 KPI41919.1 - 0.07 12.6 0.1 0.07 12.6 0.0 2.3 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation KaiC PF06745.8 KPI41919.1 - 0.079 12.0 0.2 0.19 10.8 0.2 1.5 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.1 KPI41919.1 - 0.092 12.3 0.3 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KPI41919.1 - 0.13 11.8 1.3 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 KPI41919.1 - 1.2 8.7 3.3 27 4.4 0.1 2.7 3 0 0 3 3 3 0 NTPase Abhydrolase_6 PF12697.2 KPI41920.1 - 5.6e-18 65.6 0.0 6.8e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI41920.1 - 1.9e-08 34.1 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KPI41920.1 - 2.8e-07 30.9 0.0 9.7e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain DUF2305 PF10230.4 KPI41920.1 - 5.9e-06 25.8 0.0 1.5e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 KPI41920.1 - 0.00011 21.8 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 KPI41920.1 - 0.00073 19.1 0.0 0.0045 16.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 KPI41920.1 - 0.0052 16.4 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_8 PF06259.7 KPI41920.1 - 0.016 14.7 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase PE-PPE PF08237.6 KPI41920.1 - 0.059 12.7 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Chlorophyllase2 PF12740.2 KPI41920.1 - 0.064 12.1 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Hydrolase_4 PF12146.3 KPI41920.1 - 0.14 12.0 0.1 3.2 7.6 0.0 2.5 3 0 0 3 3 3 0 Putative lysophospholipase Jiraiya PF15038.1 KPI41921.1 - 0.16 11.3 2.5 0.13 11.6 0.8 1.5 2 0 0 2 2 2 0 Jiraiya Gcd10p PF04189.8 KPI41923.1 - 2.6e-91 305.8 0.0 4.9e-91 304.9 0.0 1.4 2 0 0 2 2 2 1 Gcd10p family Mcm10 PF09332.6 KPI41923.1 - 4.5 6.5 5.4 1.6 8.0 1.2 1.8 2 0 0 2 2 2 0 Mcm10 replication factor Aldedh PF00171.17 KPI41925.1 - 9.3e-174 578.0 0.3 1e-173 577.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KPI41925.1 - 0.066 12.4 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) LuxC PF05893.9 KPI41925.1 - 0.16 10.6 0.0 0.29 9.8 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) MFS_1 PF07690.11 KPI41926.1 - 3.9e-41 140.9 45.7 3.9e-41 140.9 31.7 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KPI41926.1 - 4.7e-10 38.3 17.7 6.1e-10 37.9 12.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) COX7C PF02935.11 KPI41926.1 - 0.061 13.1 2.2 2.4 8.0 0.4 2.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Fungal_trans_2 PF11951.3 KPI41927.1 - 3.4e-23 81.8 2.4 4.2e-23 81.5 1.7 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4243 PF14027.1 KPI41929.1 - 1.8e-92 310.2 0.0 2.3e-92 309.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) TATR PF03430.8 KPI41930.1 - 0.15 10.6 0.1 0.39 9.3 0.1 1.6 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Elong_Iki1 PF10483.4 KPI41930.1 - 7.4 5.8 9.1 19 4.5 0.0 3.8 3 1 0 3 3 3 0 Elongator subunit Iki1 SpvB PF03534.8 KPI41931.1 - 4.3e-80 268.8 0.2 8.5e-80 267.8 0.1 1.5 1 0 0 1 1 1 1 Salmonella virulence plasmid 65kDa B protein TcdB_toxin_midN PF12256.3 KPI41931.1 - 5.5e-46 156.1 15.1 1.3e-37 128.9 0.0 7.6 6 1 1 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region TcdB_toxin_midC PF12255.3 KPI41931.1 - 8.3e-32 109.9 0.7 2.2e-31 108.5 0.5 1.8 1 0 0 1 1 1 1 Insecticide toxin TcdB middle/C-terminal region VCBS PF13517.1 KPI41931.1 - 1.1e-09 38.4 17.5 0.00014 22.1 0.3 5.9 4 1 3 7 7 7 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RHS_repeat PF05593.9 KPI41931.1 - 0.0012 19.0 45.8 0.21 11.7 1.2 11.4 11 3 2 13 13 13 4 RHS Repeat Mu-transpos_C PF09299.6 KPI41931.1 - 0.2 11.5 0.7 0.73 9.7 0.0 2.2 2 0 0 2 2 2 0 Mu transposase, C-terminal FG-GAP PF01839.18 KPI41931.1 - 0.27 10.9 18.3 0.048 13.3 0.2 5.6 6 0 0 6 6 6 0 FG-GAP repeat zf-MYND PF01753.13 KPI41932.1 - 9.2e-10 38.2 16.7 1.6e-09 37.5 11.6 1.4 1 0 0 1 1 1 1 MYND finger OMS28_porin PF03532.8 KPI41932.1 - 0.076 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 OMS28 porin DUF1749 PF08538.5 KPI41933.1 - 5.9e-65 219.1 0.0 7.4e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KPI41933.1 - 4.3e-06 26.7 0.1 6.8e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI41933.1 - 0.0049 16.6 0.0 0.015 15.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family adh_short PF00106.20 KPI41934.1 - 4.9e-13 49.3 0.8 1.1e-12 48.1 0.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI41934.1 - 1e-08 35.2 0.0 1.5e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI41934.1 - 5.5e-07 29.4 0.1 8e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KPI41934.1 - 0.06 12.2 0.0 0.083 11.7 0.0 1.4 1 1 0 1 1 1 0 Male sterility protein Fungal_trans_2 PF11951.3 KPI41935.1 - 2e-20 72.7 2.3 5e-10 38.5 0.5 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain DUF1176 PF06674.6 KPI41935.1 - 0.088 11.9 0.4 0.13 11.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) DUF1223 PF06764.6 KPI41937.1 - 2.2e-43 148.4 0.0 2.8e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) Pyr_redox_3 PF13738.1 KPI41939.1 - 6.6e-28 98.1 0.0 2e-27 96.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI41939.1 - 1.1e-15 56.9 0.1 3.2e-15 55.3 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KPI41939.1 - 7.7e-11 41.4 0.0 4.9e-09 35.5 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KPI41939.1 - 1.8e-09 37.4 0.0 7e-09 35.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI41939.1 - 4e-07 30.1 0.0 0.0013 18.6 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI41939.1 - 3.7e-05 22.9 0.0 0.00015 20.9 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 KPI41939.1 - 9.3e-05 21.4 0.0 0.00035 19.5 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KPI41939.1 - 0.0039 15.7 0.0 0.025 13.0 0.0 2.1 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 KPI41939.1 - 0.015 14.2 0.1 0.071 11.9 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 KPI41939.1 - 0.02 14.9 0.0 0.29 11.2 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KPI41939.1 - 0.022 15.1 0.0 17 5.8 0.0 3.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI41939.1 - 0.025 13.4 0.0 0.042 12.7 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.19 KPI41939.1 - 0.04 12.8 0.0 0.16 10.8 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KPI41939.1 - 0.4 10.4 2.1 14 5.4 0.4 3.3 3 1 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.19 KPI41940.1 - 1e-33 116.7 8.8 7.2e-33 113.9 6.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI41940.1 - 0.08 12.8 0.1 3.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2638 PF10937.3 KPI41941.1 - 0.5 11.3 7.5 0.34 11.9 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) Arginase PF00491.16 KPI41943.1 - 3.3e-70 236.5 0.4 2.3e-69 233.7 0.3 1.9 1 1 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KPI41943.1 - 0.05 13.7 0.4 0.65 10.1 0.1 2.1 2 0 0 2 2 2 0 UPF0489 domain DHHA1 PF02272.14 KPI41944.1 - 3.1 7.5 6.2 19 5.0 0.0 2.4 2 0 0 2 2 2 0 DHHA1 domain CAP_GLY PF01302.20 KPI41945.1 - 6.5e-18 64.2 0.0 1.2e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 KPI41945.1 - 1.6e-11 43.5 20.5 2.4e-05 23.8 0.3 6.5 4 1 5 9 9 9 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KPI41945.1 - 1.1e-06 28.0 20.8 0.49 10.6 0.5 7.9 7 1 1 8 8 8 3 Leucine Rich repeat LRR_8 PF13855.1 KPI41945.1 - 0.00021 20.9 19.9 0.11 12.2 3.4 4.9 3 2 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 KPI41945.1 - 0.026 14.4 15.5 1.4 9.2 0.2 6.6 5 2 1 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 KPI41945.1 - 0.1 12.8 18.9 2.9 8.4 0.0 7.2 9 0 0 9 9 9 0 Leucine rich repeat BTB PF00651.26 KPI41946.1 - 0.0041 17.0 0.0 0.02 14.8 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Fungal_trans PF04082.13 KPI41947.1 - 1e-08 34.4 2.2 1.5e-08 33.8 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KPI41948.1 - 4.6e-30 104.5 27.2 7.4e-30 103.8 18.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily HLH PF00010.21 KPI41949.1 - 1e-08 34.7 0.0 3.1e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Abhydrolase_6 PF12697.2 KPI41950.1 - 4.8e-14 52.7 0.0 7.7e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI41950.1 - 2.7e-06 27.1 0.0 5.7e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KPI41950.1 - 0.0044 16.6 0.0 0.0081 15.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 KPI41950.1 - 0.0051 16.2 0.0 0.011 15.1 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Thioesterase PF00975.15 KPI41950.1 - 0.075 13.2 0.1 0.62 10.2 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_8 PF06259.7 KPI41950.1 - 0.095 12.1 0.1 0.29 10.6 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase Frataxin_Cyay PF01491.11 KPI41951.1 - 3.6e-29 100.7 0.0 1.3e-28 98.9 0.0 1.8 1 1 0 1 1 1 1 Frataxin-like domain Fungal_trans PF04082.13 KPI41952.1 - 5e-24 84.5 0.1 9.1e-24 83.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI41952.1 - 8.6e-09 35.1 11.7 1.9e-08 34.0 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 KPI41954.1 - 3.9e-27 95.2 3.9 6.2e-27 94.5 2.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KPI41954.1 - 3.1e-20 72.8 0.0 7.1e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KPI41954.1 - 3.1e-16 58.6 0.1 6.6e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KPI41954.1 - 3.6e-10 40.2 2.9 6.2e-10 39.4 2.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glucosaminidase PF01832.15 KPI41954.1 - 0.0038 17.3 0.1 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Cys_Met_Meta_PP PF01053.15 KPI41955.1 - 7.5e-149 495.2 0.0 8.6e-149 495.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KPI41955.1 - 1.2e-12 47.6 0.1 1.9e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KPI41955.1 - 6.4e-10 38.5 0.0 1e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KPI41955.1 - 3.9e-09 35.7 0.0 5.8e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KPI41955.1 - 4.5e-07 29.2 0.0 7.7e-07 28.5 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 KPI41955.1 - 0.00029 19.6 0.0 0.00046 18.9 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 KPI41955.1 - 0.00051 18.4 0.0 0.00067 18.0 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 KPI41955.1 - 0.025 13.0 0.0 0.032 12.6 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) CPSase_L_D2 PF02786.12 KPI41955.1 - 0.16 11.2 0.4 0.32 10.2 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain AIG2 PF06094.7 KPI41957.1 - 8.4e-15 55.1 0.0 1.4e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family DUF2095 PF09868.4 KPI41957.1 - 0.04 13.6 0.1 0.061 13.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) TauD PF02668.11 KPI41958.1 - 4.1e-45 154.4 0.5 4.7e-45 154.2 0.4 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 KPI41960.1 - 1.3e-33 116.2 41.0 1.5e-33 115.9 27.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI41960.1 - 3.2e-12 45.7 9.7 3.2e-12 45.7 6.7 2.1 2 2 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 KPI41960.1 - 2.2 6.2 8.6 0.4 8.6 1.4 2.3 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Pro_CA PF00484.14 KPI41961.1 - 7.7e-07 29.2 0.3 0.00011 22.2 0.1 2.5 2 1 0 2 2 2 2 Carbonic anhydrase Clr5 PF14420.1 KPI41962.1 - 3e-15 55.8 0.2 4.8e-15 55.1 0.2 1.3 1 0 0 1 1 1 1 Clr5 domain Med3 PF11593.3 KPI41962.1 - 0.046 12.9 13.8 0.078 12.1 9.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Herpes_capsid PF06112.6 KPI41962.1 - 1.2 9.1 11.6 2.3 8.2 8.0 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Mucin PF01456.12 KPI41962.1 - 3.1 7.5 29.3 7.3 6.3 20.3 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Aldedh PF00171.17 KPI41963.1 - 4e-144 480.4 0.0 4.5e-144 480.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Asp_Glu_race PF01177.17 KPI41964.1 - 2.1e-18 67.0 0.0 2.5e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Aldo_ket_red PF00248.16 KPI41965.1 - 9.9e-60 201.7 0.2 1.3e-59 201.3 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PVL_ORF50 PF07768.6 KPI41966.1 - 0.36 10.8 3.0 0.36 10.8 0.3 2.3 1 1 1 2 2 2 0 PVL ORF-50-like family EHN PF06441.7 KPI41967.1 - 1e-36 125.2 0.8 3.2e-36 123.6 0.0 2.0 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 KPI41967.1 - 1.3e-09 37.9 0.0 2.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI41967.1 - 2.2e-07 31.0 0.9 5.6e-07 29.6 0.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Clc-like PF07062.7 KPI41968.1 - 0.011 14.9 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Clc-like Pyrophosphatase PF00719.14 KPI41968.1 - 0.12 11.7 0.0 0.95 8.8 0.0 2.0 2 0 0 2 2 2 0 Inorganic pyrophosphatase BTB PF00651.26 KPI41969.1 - 9.1e-08 32.0 0.0 7.7e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain GST_N_3 PF13417.1 KPI41970.1 - 3.7e-12 46.2 0.0 7.7e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI41970.1 - 2.4e-09 37.0 0.0 6.2e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KPI41970.1 - 0.00015 21.8 0.0 0.00042 20.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GMC_oxred_N PF00732.14 KPI41972.1 - 7.9e-62 209.0 0.0 1e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI41972.1 - 3.3e-30 105.2 0.0 6.1e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KPI41972.1 - 4.5e-06 25.8 0.1 0.012 14.5 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KPI41972.1 - 1.4e-05 24.2 0.2 2.1e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KPI41972.1 - 3.3e-05 22.9 1.8 0.047 12.5 1.4 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 KPI41972.1 - 0.0069 15.5 0.1 0.017 14.2 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KPI41972.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KPI41972.1 - 0.013 14.5 2.0 0.29 10.1 2.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KPI41972.1 - 0.038 12.8 0.1 0.062 12.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 KPI41972.1 - 0.12 10.8 0.4 0.21 10.0 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein DUF1385 PF07136.6 KPI41972.1 - 0.21 10.6 0.1 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) Aldedh PF00171.17 KPI41973.1 - 7.6e-141 469.5 0.0 9.9e-141 469.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KPI41973.1 - 0.00037 19.3 0.0 0.00083 18.1 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KPI41973.1 - 0.1 11.7 0.1 0.71 9.0 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Filament PF00038.16 KPI41974.1 - 0.0007 19.1 0.8 0.00085 18.8 0.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein bZIP_1 PF00170.16 KPI41974.1 - 0.00075 19.4 2.4 0.00075 19.4 1.6 2.1 1 1 1 2 2 2 1 bZIP transcription factor BicD PF09730.4 KPI41974.1 - 0.0015 16.9 0.1 0.0017 16.8 0.1 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D TPR_MLP1_2 PF07926.7 KPI41974.1 - 0.0016 18.2 2.0 0.004 16.8 1.3 1.6 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein IncA PF04156.9 KPI41974.1 - 0.0025 17.4 0.1 0.0029 17.2 0.0 1.1 1 0 0 1 1 1 1 IncA protein CENP-H PF05837.7 KPI41974.1 - 0.003 17.6 2.3 0.0041 17.2 1.6 1.2 1 0 0 1 1 1 1 Centromere protein H (CENP-H) HemX PF04375.9 KPI41974.1 - 0.0031 16.1 0.3 0.0034 16.0 0.2 1.1 1 0 0 1 1 1 1 HemX ATG16 PF08614.6 KPI41974.1 - 0.0032 17.3 0.8 0.0035 17.1 0.6 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) APG6 PF04111.7 KPI41974.1 - 0.0038 16.3 0.7 0.004 16.2 0.5 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 Vps5 PF09325.5 KPI41974.1 - 0.0041 16.4 0.3 0.0048 16.1 0.2 1.1 1 0 0 1 1 1 1 Vps5 C terminal like DUF745 PF05335.8 KPI41974.1 - 0.0076 15.7 1.0 0.0098 15.4 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF745) EzrA PF06160.7 KPI41974.1 - 0.01 14.0 0.3 0.011 13.9 0.2 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DMPK_coil PF08826.5 KPI41974.1 - 0.011 15.5 2.6 0.041 13.7 0.3 2.1 2 0 0 2 2 2 0 DMPK coiled coil domain like Tup_N PF08581.5 KPI41974.1 - 0.012 15.7 1.6 0.025 14.7 0.1 2.1 1 1 2 3 3 3 0 Tup N-terminal Rootletin PF15035.1 KPI41974.1 - 0.013 15.4 3.1 0.016 15.1 2.2 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Snapin_Pallidin PF14712.1 KPI41974.1 - 0.016 15.5 0.4 0.026 14.8 0.3 1.3 1 1 0 1 1 1 0 Snapin/Pallidin DivIC PF04977.10 KPI41974.1 - 0.021 14.3 2.9 0.03 13.7 1.5 1.6 1 1 0 1 1 1 0 Septum formation initiator Tropomyosin_1 PF12718.2 KPI41974.1 - 0.021 14.6 3.6 0.053 13.3 2.5 1.6 1 1 0 1 1 1 0 Tropomyosin like HAP1_N PF04849.8 KPI41974.1 - 0.022 13.7 4.0 0.041 12.8 0.7 2.0 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Nnf1 PF03980.9 KPI41974.1 - 0.023 14.6 0.6 0.041 13.8 0.1 1.6 2 0 0 2 2 2 0 Nnf1 Fib_alpha PF08702.5 KPI41974.1 - 0.024 14.7 0.5 0.041 14.0 0.4 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Pox_A_type_inc PF04508.7 KPI41974.1 - 0.028 14.1 2.5 0.38 10.6 0.1 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat TBPIP PF07106.8 KPI41974.1 - 0.033 13.7 1.0 0.045 13.2 0.7 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_DNA_bd PF12329.3 KPI41974.1 - 0.042 13.6 5.5 0.24 11.2 2.0 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Mod_r PF07200.8 KPI41974.1 - 0.044 13.7 1.3 0.057 13.3 0.9 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Nup54 PF13874.1 KPI41974.1 - 0.048 13.3 1.2 0.57 9.8 0.4 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Tropomyosin PF00261.15 KPI41974.1 - 0.05 12.6 3.9 0.072 12.1 2.7 1.3 1 1 0 1 1 1 0 Tropomyosin Reo_sigmaC PF04582.7 KPI41974.1 - 0.053 12.6 0.0 0.058 12.5 0.0 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein bZIP_2 PF07716.10 KPI41974.1 - 0.056 13.2 4.9 0.17 11.7 1.1 2.3 2 0 0 2 2 2 0 Basic region leucine zipper BLOC1_2 PF10046.4 KPI41974.1 - 0.057 13.5 0.2 0.078 13.1 0.2 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCC-bdg_PDZ PF10506.4 KPI41974.1 - 0.065 13.0 2.3 0.1 12.4 1.6 1.3 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Mnd1 PF03962.10 KPI41974.1 - 0.089 12.4 2.2 0.12 12.0 1.5 1.1 1 0 0 1 1 1 0 Mnd1 family DUF972 PF06156.8 KPI41974.1 - 0.09 13.1 2.0 0.14 12.4 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) TraC PF07820.7 KPI41974.1 - 0.098 12.8 0.4 0.43 10.8 0.1 2.1 1 1 1 2 2 2 0 TraC-like protein DUF4201 PF13870.1 KPI41974.1 - 0.11 11.9 3.9 0.56 9.6 0.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Spectrin PF00435.16 KPI41974.1 - 0.11 12.7 2.4 0.19 12.0 1.7 1.4 1 1 0 1 1 1 0 Spectrin repeat YscO PF07321.7 KPI41974.1 - 0.12 12.2 2.2 0.16 11.7 1.5 1.2 1 0 0 1 1 1 0 Type III secretion protein YscO Ax_dynein_light PF10211.4 KPI41974.1 - 0.15 11.8 2.3 0.2 11.5 1.6 1.3 1 1 0 1 1 1 0 Axonemal dynein light chain GrpE PF01025.14 KPI41974.1 - 0.17 11.3 3.5 0.13 11.7 1.1 1.6 1 1 1 2 2 2 0 GrpE DUF2721 PF11026.3 KPI41974.1 - 0.34 10.5 1.2 0.35 10.5 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Prefoldin_2 PF01920.15 KPI41974.1 - 0.64 9.8 3.7 1.9 8.2 1.6 2.0 1 1 1 2 2 2 0 Prefoldin subunit Phe_tRNA-synt_N PF02912.13 KPI41974.1 - 2.6 7.8 6.0 2.2 8.0 0.2 2.2 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain DivIVA PF05103.8 KPI41975.1 - 0.0028 17.6 1.3 0.0028 17.6 0.9 2.5 3 0 0 3 3 3 1 DivIVA protein Sds3 PF08598.6 KPI41975.1 - 0.013 15.0 0.7 0.033 13.7 0.5 1.7 1 0 0 1 1 1 0 Sds3-like Fungal_trans PF04082.13 KPI41976.1 - 3e-22 78.7 0.4 5.8e-22 77.8 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3425 PF11905.3 KPI41976.1 - 1.7e-12 47.4 4.3 1.7e-12 47.4 3.0 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF3425) COesterase PF00135.23 KPI41977.1 - 2.3e-107 359.9 0.0 3e-107 359.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI41977.1 - 5.1e-07 29.4 1.7 1.8e-06 27.6 0.2 2.4 2 2 0 2 2 2 1 alpha/beta hydrolase fold MFS_1 PF07690.11 KPI41978.1 - 9.1e-38 129.8 19.7 1.3e-37 129.3 13.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.13 KPI41979.1 - 5.1e-08 32.6 8.3 1.1e-07 31.6 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KPI41979.1 - 0.0089 14.9 1.4 0.026 13.3 1.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4267 PF14087.1 KPI41980.1 - 0.0016 18.0 0.7 0.002 17.6 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Prp31_C PF09785.4 KPI41981.1 - 7.2e-45 152.4 1.7 1.8e-44 151.1 1.2 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 KPI41981.1 - 1.2e-36 125.2 0.1 2.8e-36 124.0 0.1 1.6 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 KPI41981.1 - 9.6e-21 73.3 0.0 1.8e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain MFS_1 PF07690.11 KPI41982.1 - 5.3e-22 78.0 30.8 2.2e-21 76.0 20.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_glycop_gL PF11108.3 KPI41982.1 - 0.022 14.7 0.0 0.064 13.2 0.0 1.8 1 0 0 1 1 1 0 Viral glycoprotein L Aldo_ket_red PF00248.16 KPI41983.1 - 2.8e-53 180.5 0.0 3.3e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UDPGT PF00201.13 KPI41983.1 - 0.0049 15.4 0.0 0.013 14.1 0.0 1.5 1 1 1 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Scytalone_dh PF02982.9 KPI41985.1 - 2.5e-39 134.4 0.2 2.9e-39 134.2 0.1 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 KPI41985.1 - 3.2e-08 33.5 0.3 4.1e-08 33.1 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain Nefa_Nip30_N PF10187.4 KPI41986.1 - 1.6e-24 86.0 9.3 1.6e-24 86.0 6.4 1.9 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2075 PF09848.4 KPI41986.1 - 0.0078 15.2 1.5 0.01 14.8 1.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Coiled-coil_56 PF09813.4 KPI41986.1 - 0.58 10.1 8.6 0.065 13.2 2.8 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 MCPVI PF02993.9 KPI41986.1 - 5.2 7.1 14.1 2 8.4 5.3 2.0 2 0 0 2 2 2 0 Minor capsid protein VI Mito_carr PF00153.22 KPI41987.1 - 1.5e-27 95.1 1.1 1.9e-15 56.3 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Hydrolase_like2 PF13246.1 KPI41987.1 - 0.0058 16.5 0.1 0.14 12.0 0.0 2.8 2 2 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Spore_III_AB PF09548.5 KPI41988.1 - 0.049 13.3 0.4 0.23 11.1 0.0 2.3 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) F_actin_bind PF08919.5 KPI41988.1 - 0.075 12.7 0.0 0.51 10.0 0.0 2.4 2 0 0 2 2 2 0 F-actin binding DUF3910 PF13049.1 KPI41988.1 - 0.091 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3910) ProQ PF04352.8 KPI41988.1 - 0.11 12.1 0.0 0.57 9.8 0.0 2.2 2 0 0 2 2 2 0 ProQ/FINO family DAO PF01266.19 KPI41989.1 - 1.7e-30 106.1 0.2 2e-30 105.9 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI41989.1 - 1.5e-07 30.6 0.1 2.3e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KPI41989.1 - 2.4e-06 27.4 1.1 4.5e-06 26.5 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI41989.1 - 0.00028 20.8 0.9 0.0012 18.7 0.6 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KPI41989.1 - 0.00032 20.1 0.4 0.0007 19.0 0.2 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 KPI41989.1 - 0.00034 19.7 0.6 0.0014 17.8 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 KPI41989.1 - 0.00059 18.7 0.1 0.065 12.0 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KPI41989.1 - 0.00074 18.5 0.2 0.23 10.3 0.2 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.12 KPI41989.1 - 0.0019 17.3 0.1 0.0038 16.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KPI41989.1 - 0.0028 18.0 0.6 0.0084 16.4 0.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KPI41989.1 - 0.0046 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_2 PF03446.10 KPI41989.1 - 0.0076 16.1 0.0 0.026 14.3 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KPI41989.1 - 0.01 15.5 0.7 0.017 14.8 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KPI41989.1 - 0.012 15.0 0.3 0.024 14.0 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 KPI41989.1 - 0.027 12.9 0.2 0.048 12.1 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 KPI41989.1 - 0.037 13.1 0.6 0.14 11.2 0.4 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 KPI41989.1 - 0.044 13.7 0.2 1.9 8.4 0.1 2.6 2 1 1 3 3 3 0 NADH(P)-binding Pyr_redox_3 PF13738.1 KPI41989.1 - 0.056 13.4 0.1 0.18 11.8 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI41989.1 - 0.1 12.3 0.1 15 5.3 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding F420_oxidored PF03807.12 KPI41989.1 - 0.13 12.7 0.1 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AFG1_ATPase PF03969.11 KPI41991.1 - 3.3e-47 161.0 1.7 1.3e-23 83.4 0.0 4.9 5 0 0 5 5 5 3 AFG1-like ATPase AAA_16 PF13191.1 KPI41991.1 - 6.3e-05 23.0 0.5 0.00084 19.3 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KPI41991.1 - 0.0073 16.4 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KPI41991.1 - 0.0097 16.0 0.0 0.027 14.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KPI41991.1 - 0.13 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IncA PF04156.9 KPI41992.1 - 6.3e-06 25.9 0.2 6.4e-06 25.8 0.1 1.0 1 0 0 1 1 1 1 IncA protein ADIP PF11559.3 KPI41992.1 - 6.8e-05 22.8 1.0 7.3e-05 22.7 0.7 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding HALZ PF02183.13 KPI41992.1 - 0.00012 21.7 3.1 0.002 17.7 0.8 2.5 2 0 0 2 2 2 1 Homeobox associated leucine zipper Rootletin PF15035.1 KPI41992.1 - 0.00014 21.8 2.3 0.00018 21.5 1.6 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DUF904 PF06005.7 KPI41992.1 - 0.00044 20.4 5.7 0.0028 17.9 3.9 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF904) DivIC PF04977.10 KPI41992.1 - 0.00065 19.1 3.9 0.0021 17.5 1.3 2.3 1 1 1 2 2 2 1 Septum formation initiator DUF2353 PF09789.4 KPI41992.1 - 0.00071 18.9 1.4 0.00088 18.6 1.0 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) DivIVA PF05103.8 KPI41992.1 - 0.00076 19.5 2.1 0.00095 19.2 1.4 1.2 1 0 0 1 1 1 1 DivIVA protein DMPK_coil PF08826.5 KPI41992.1 - 0.0012 18.6 3.3 1.6 8.7 0.0 3.0 1 1 2 3 3 3 2 DMPK coiled coil domain like Myosin_tail_1 PF01576.14 KPI41992.1 - 0.0013 16.6 4.6 0.0014 16.4 3.2 1.0 1 0 0 1 1 1 1 Myosin tail WEMBL PF05701.6 KPI41992.1 - 0.0015 17.0 1.2 0.0015 17.0 0.9 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Spc7 PF08317.6 KPI41992.1 - 0.0017 17.1 2.0 0.0025 16.5 1.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Filament PF00038.16 KPI41992.1 - 0.0034 16.8 2.1 0.0048 16.4 1.5 1.3 1 0 0 1 1 1 1 Intermediate filament protein DUF972 PF06156.8 KPI41992.1 - 0.0042 17.4 3.1 0.023 15.0 2.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF972) WXG100 PF06013.7 KPI41992.1 - 0.007 16.3 0.5 2.3 8.2 0.0 2.5 1 1 1 2 2 2 0 Proteins of 100 residues with WXG USP8_interact PF08941.5 KPI41992.1 - 0.0071 15.6 0.3 0.012 14.9 0.2 1.4 1 1 0 1 1 1 1 USP8 interacting bZIP_1 PF00170.16 KPI41992.1 - 0.0073 16.2 6.3 0.12 12.3 2.6 2.4 1 1 0 2 2 2 1 bZIP transcription factor CENP-F_leu_zip PF10473.4 KPI41992.1 - 0.0081 16.0 2.6 0.011 15.5 1.8 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 KPI41992.1 - 0.0097 15.6 3.0 0.028 14.1 1.6 1.8 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein DUF1875 PF08961.5 KPI41992.1 - 0.011 15.1 0.9 0.013 14.8 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) CCDC155 PF14662.1 KPI41992.1 - 0.012 15.1 4.9 0.15 11.6 1.1 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Ax_dynein_light PF10211.4 KPI41992.1 - 0.017 14.9 2.9 0.021 14.6 1.5 1.6 1 1 1 2 2 2 0 Axonemal dynein light chain Rab5-bind PF09311.6 KPI41992.1 - 0.019 14.8 3.1 0.022 14.6 1.8 1.4 1 1 0 1 1 1 0 Rabaptin-like protein GAS PF13851.1 KPI41992.1 - 0.02 14.1 2.0 0.029 13.5 1.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.4 KPI41992.1 - 0.021 14.9 0.9 0.97 9.6 0.4 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 KPI41992.1 - 0.022 15.0 1.0 0.07 13.3 0.7 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.1 KPI41992.1 - 0.023 14.1 3.7 0.036 13.5 2.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) APG6 PF04111.7 KPI41992.1 - 0.026 13.5 2.4 0.029 13.4 1.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_2 PF07716.10 KPI41992.1 - 0.027 14.3 5.4 0.13 12.0 0.4 3.0 2 1 1 3 3 3 0 Basic region leucine zipper Prefoldin_3 PF13758.1 KPI41992.1 - 0.027 14.2 0.5 0.053 13.3 0.4 1.6 1 1 0 1 1 1 0 Prefoldin subunit RNase_E_G PF10150.4 KPI41992.1 - 0.027 13.7 1.4 0.031 13.5 1.0 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family TBPIP PF07106.8 KPI41992.1 - 0.028 13.9 2.4 0.076 12.5 1.6 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 KPI41992.1 - 0.028 12.2 0.6 0.031 12.1 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4618 PF15397.1 KPI41992.1 - 0.028 13.7 2.3 0.1 11.9 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Laminin_II PF06009.7 KPI41992.1 - 0.029 14.1 0.7 0.053 13.2 0.4 1.5 1 1 0 1 1 1 0 Laminin Domain II Spectrin PF00435.16 KPI41992.1 - 0.031 14.5 1.8 0.074 13.3 1.3 1.6 1 1 0 1 1 1 0 Spectrin repeat SlyX PF04102.7 KPI41992.1 - 0.032 14.6 1.3 0.09 13.1 0.7 1.8 1 1 1 2 2 2 0 SlyX Phasin PF05597.6 KPI41992.1 - 0.034 13.9 0.7 2.5 7.8 0.0 2.2 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Fib_alpha PF08702.5 KPI41992.1 - 0.041 14.0 0.7 0.049 13.7 0.5 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 KPI41992.1 - 0.044 13.6 1.0 0.32 10.8 0.4 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Occludin_ELL PF07303.8 KPI41992.1 - 0.047 14.4 0.3 0.056 14.1 0.2 1.1 1 0 0 1 1 1 0 Occludin homology domain TMF_DNA_bd PF12329.3 KPI41992.1 - 0.05 13.4 5.7 0.14 12.0 4.0 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 KPI41992.1 - 0.056 13.3 3.9 1.6 8.7 2.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Prefoldin_2 PF01920.15 KPI41992.1 - 0.058 13.1 4.3 0.42 10.4 1.1 2.1 1 1 1 2 2 2 0 Prefoldin subunit TMF_TATA_bd PF12325.3 KPI41992.1 - 0.058 13.1 6.1 0.11 12.2 4.3 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding MAD PF05557.8 KPI41992.1 - 0.059 11.4 4.7 0.67 7.9 1.0 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein FlaC_arch PF05377.6 KPI41992.1 - 0.071 13.0 1.3 9.3 6.2 0.4 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) KxDL PF10241.4 KPI41992.1 - 0.074 12.9 0.5 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein RPW8 PF05659.6 KPI41992.1 - 0.076 12.5 0.7 0.12 11.9 0.5 1.3 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Reo_sigmaC PF04582.7 KPI41992.1 - 0.086 12.0 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CK2S PF15011.1 KPI41992.1 - 0.086 12.6 1.6 1.7 8.4 0.4 2.1 1 1 1 2 2 2 0 Casein Kinase 2 substrate Seryl_tRNA_N PF02403.17 KPI41992.1 - 0.086 12.8 4.2 1.7 8.7 1.3 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Sec20 PF03908.8 KPI41992.1 - 0.092 12.4 0.3 0.14 11.8 0.2 1.4 1 1 0 1 1 1 0 Sec20 M PF02370.11 KPI41992.1 - 0.095 13.0 5.0 44 4.9 0.8 3.6 2 1 2 4 4 4 0 M protein repeat TSC22 PF01166.13 KPI41992.1 - 0.11 12.5 5.2 0.11 12.5 1.5 2.3 2 1 0 2 2 2 0 TSC-22/dip/bun family Atg14 PF10186.4 KPI41992.1 - 0.11 11.4 2.0 0.13 11.2 1.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PilJ PF13675.1 KPI41992.1 - 0.13 12.5 0.3 0.77 10.0 0.2 1.9 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Halogen_Hydrol PF10112.4 KPI41992.1 - 0.16 11.3 1.0 2.9 7.2 0.2 2.1 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein ATG16 PF08614.6 KPI41992.1 - 0.19 11.5 5.4 0.39 10.5 1.9 1.8 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4446 PF14584.1 KPI41992.1 - 0.21 11.4 2.3 1.2 8.9 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Spc24 PF08286.6 KPI41992.1 - 0.23 11.1 5.1 0.33 10.6 1.9 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Fez1 PF06818.10 KPI41992.1 - 0.27 11.2 5.2 0.31 11.0 3.6 1.1 1 0 0 1 1 1 0 Fez1 Ribosomal_L29 PF00831.18 KPI41992.1 - 0.31 10.7 3.9 1.6 8.4 1.4 2.4 2 1 0 2 2 2 0 Ribosomal L29 protein zf-C4H2 PF10146.4 KPI41992.1 - 0.35 10.8 4.0 0.66 9.9 2.8 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein CorA PF01544.13 KPI41992.1 - 0.43 9.5 2.0 0.54 9.2 1.4 1.2 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein bZIP_Maf PF03131.12 KPI41992.1 - 0.43 10.9 4.6 2 8.7 1.4 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor Microtub_assoc PF07989.6 KPI41992.1 - 0.47 10.3 3.3 2 8.3 1.5 2.4 1 1 1 2 2 2 0 Microtubule associated EMP24_GP25L PF01105.19 KPI41992.1 - 0.48 10.1 2.4 1.2 8.8 0.7 1.8 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Cep57_CLD_2 PF14197.1 KPI41992.1 - 1.4 8.9 6.8 17 5.4 0.1 2.6 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 Lactamase_B_2 PF12706.2 KPI41993.1 - 1.2e-06 28.2 0.1 1.4e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KPI41993.1 - 6.6e-06 25.9 1.3 1.2e-05 25.1 0.9 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 KPI41993.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Fungal_trans PF04082.13 KPI41994.1 - 1.2e-07 30.8 0.0 0.00071 18.5 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI41994.1 - 4.1e-06 26.5 11.2 6.9e-06 25.8 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHORD PF04968.7 KPI41995.1 - 0.026 14.7 2.4 0.19 11.9 0.1 2.2 2 0 0 2 2 2 0 CHORD zf-ribbon_3 PF13248.1 KPI41995.1 - 0.044 13.0 0.1 0.082 12.1 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Ank_2 PF12796.2 KPI41996.1 - 5.9e-13 48.9 0.2 4.4e-07 30.1 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KPI41996.1 - 4.5e-12 46.1 0.1 1.8e-05 25.1 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeats (many copies) TPR_12 PF13424.1 KPI41996.1 - 7.6e-09 35.3 1.4 0.00054 19.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KPI41996.1 - 5.5e-08 32.1 4.6 0.0073 16.1 0.4 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KPI41996.1 - 7.1e-08 31.7 5.9 0.029 13.9 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 KPI41996.1 - 6e-07 29.5 1.9 3.5e-05 23.8 0.2 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KPI41996.1 - 2.1e-06 27.9 1.4 0.0039 17.4 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Ank PF00023.25 KPI41996.1 - 3e-06 26.7 0.1 0.0031 17.2 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat TPR_11 PF13414.1 KPI41996.1 - 2e-05 24.1 4.0 0.0017 17.9 0.4 2.7 1 1 1 2 2 2 2 TPR repeat TPR_7 PF13176.1 KPI41996.1 - 6.6e-05 22.4 0.4 0.2 11.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Ank_5 PF13857.1 KPI41996.1 - 6.6e-05 23.0 0.1 0.28 11.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) TPR_8 PF13181.1 KPI41996.1 - 0.00016 21.2 6.0 0.001 18.6 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KPI41996.1 - 0.00017 21.9 0.1 6.8 7.6 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KPI41996.1 - 0.00039 20.2 0.1 0.031 14.1 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Ank_3 PF13606.1 KPI41996.1 - 0.001 19.1 0.4 6.9 7.2 0.0 5.3 5 1 0 5 5 4 1 Ankyrin repeat TPR_6 PF13174.1 KPI41996.1 - 0.0013 19.0 1.5 3.4 8.3 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KPI41996.1 - 0.028 15.0 0.4 6.7 7.5 0.0 3.2 1 1 1 2 2 2 0 Tetratricopeptide repeat SAP PF02037.22 KPI41997.1 - 0.0012 18.2 0.1 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 SAP domain FAD_binding_4 PF01565.18 KPI41998.1 - 8.9e-23 80.3 0.8 1.4e-22 79.6 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Fungal_trans_2 PF11951.3 KPI41999.1 - 3e-10 39.2 0.5 6e-10 38.2 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain P21-Arc PF04062.9 KPI42000.1 - 2.2e-69 232.7 0.0 4.1e-69 231.8 0.0 1.4 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit IF4E PF01652.13 KPI42000.1 - 6.5e-51 172.1 0.0 1.1e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.14 KPI42000.1 - 1.2e-31 109.9 0.1 2.2e-31 109.2 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Citrate_synt PF00285.16 KPI42001.1 - 6.3e-84 281.7 0.0 1.2e-63 215.0 0.0 2.0 1 1 1 2 2 2 2 Citrate synthase p450 PF00067.17 KPI42002.1 - 1.1e-65 222.0 0.0 1.3e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DnaJ PF00226.26 KPI42004.1 - 1.1e-09 37.9 0.2 2.6e-09 36.6 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain adh_short_C2 PF13561.1 KPI42005.1 - 4.2e-28 98.7 0.2 5e-28 98.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI42005.1 - 2.9e-20 72.8 3.4 3.9e-20 72.4 2.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI42005.1 - 8.8e-10 38.5 0.7 1.2e-09 38.1 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI42005.1 - 0.002 17.5 0.2 0.0091 15.4 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KPI42005.1 - 0.0063 15.4 0.1 0.027 13.4 0.0 1.9 1 1 1 2 2 2 1 Male sterility protein YjeF_N PF03853.10 KPI42005.1 - 0.0094 15.5 0.3 0.015 14.9 0.2 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus Radical_SAM PF04055.16 KPI42005.1 - 0.11 12.6 0.0 0.99 9.5 0.0 2.0 2 0 0 2 2 2 0 Radical SAM superfamily ILVD_EDD PF00920.16 KPI42006.1 - 4.8e-146 487.2 0.0 6.1e-146 486.8 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family TENA_THI-4 PF03070.11 KPI42006.1 - 6.3e-05 22.8 0.0 0.00021 21.1 0.0 1.8 1 1 0 1 1 1 1 TENA/THI-4/PQQC family DUF1875 PF08961.5 KPI42006.1 - 0.097 11.9 0.1 0.23 10.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) Glyco_hydro_16 PF00722.16 KPI42008.1 - 1.1e-10 41.1 0.1 5.3e-10 38.8 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 PIR PF00399.14 KPI42008.1 - 4.5e-05 22.6 1.6 4.5e-05 22.6 1.1 2.7 2 0 0 2 2 2 1 Yeast PIR protein repeat GMC_oxred_N PF00732.14 KPI42009.1 - 2.4e-57 194.3 0.0 3.1e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI42009.1 - 9.2e-37 126.5 0.0 2.5e-36 125.1 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 KPI42009.1 - 2.9e-05 23.1 0.1 0.018 13.9 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI42009.1 - 0.0033 17.4 0.9 0.032 14.2 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KPI42009.1 - 0.0049 15.8 0.0 0.0093 14.9 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 KPI42009.1 - 0.088 11.6 2.4 3.1 6.5 0.6 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HhH-GPD PF00730.20 KPI42010.1 - 0.002 18.3 0.0 0.0042 17.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein VirB3 PF05101.8 KPI42010.1 - 0.066 13.2 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Transp_cyt_pur PF02133.10 KPI42011.1 - 6.3e-68 229.3 39.5 7.8e-68 229.0 27.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Baculo_PEP_C PF04513.7 KPI42012.1 - 0.0054 16.5 0.3 0.0094 15.7 0.2 1.4 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus AATF-Che1 PF13339.1 KPI42012.1 - 0.2 11.8 1.2 0.26 11.4 0.8 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Tape_meas_lam_C PF09718.5 KPI42012.1 - 3.6 7.5 15.3 0.76 9.7 2.4 2.8 1 1 2 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Mago_nashi PF02792.9 KPI42013.1 - 3.2e-75 250.5 0.2 3.8e-75 250.3 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein GFA PF04828.9 KPI42014.1 - 9.9e-18 63.8 0.1 9.9e-18 63.8 0.0 1.4 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 KPI42014.1 - 0.19 11.4 0.1 0.19 11.4 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal Elf1 PF05129.8 KPI42014.1 - 0.21 11.2 2.4 0.72 9.5 0.9 2.0 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.2 KPI42014.1 - 0.47 10.3 6.1 6.5 6.6 4.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon DUF4300 PF14133.1 KPI42015.1 - 0.055 12.7 0.2 0.1 11.8 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4300) Dynamin_M PF01031.15 KPI42016.1 - 1.3e-106 355.7 0.3 2.8e-106 354.6 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KPI42016.1 - 3.5e-56 189.6 0.0 8.1e-56 188.4 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KPI42016.1 - 8.7e-29 99.2 6.9 8.7e-29 99.2 4.8 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KPI42016.1 - 0.00029 20.7 0.2 0.0032 17.4 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KPI42016.1 - 0.04 14.4 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein CoA_trans PF01144.18 KPI42017.1 - 1.1e-100 335.2 3.8 6.4e-61 205.2 0.3 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KPI42017.1 - 0.0011 18.7 0.2 0.0021 17.7 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AMP-binding_C PF13193.1 KPI42018.1 - 0.016 16.1 0.0 0.033 15.1 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain ORC5_C PF14630.1 KPI42019.1 - 7.7e-30 104.2 0.1 3.3e-29 102.1 0.0 1.8 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 KPI42019.1 - 0.0067 16.4 1.3 0.0067 16.4 0.9 2.5 2 2 0 2 2 2 1 AAA ATPase domain DUF1776 PF08643.5 KPI42019.1 - 0.15 11.1 0.5 0.3 10.1 0.1 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) ADH_N PF08240.7 KPI42021.1 - 3.7e-21 74.9 0.2 3.7e-21 74.9 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI42021.1 - 3.4e-15 55.7 4.3 3.7e-14 52.4 3.0 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 KPI42021.1 - 0.17 11.9 1.3 0.41 10.7 0.9 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ECH PF00378.15 KPI42022.1 - 6e-45 153.2 0.0 3.3e-35 121.3 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KPI42022.1 - 0.0018 18.0 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 DUF3005 PF11448.3 KPI42022.1 - 0.013 15.1 1.1 0.67 9.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3005) Fe-ADH PF00465.14 KPI42023.1 - 2.1e-62 210.8 0.0 2.5e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KPI42023.1 - 1.5e-10 40.7 0.0 2.2e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Aldo_ket_red PF00248.16 KPI42024.1 - 1.8e-50 171.3 0.0 2.3e-32 111.9 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Sugar_tr PF00083.19 KPI42025.1 - 2.2e-73 247.3 19.7 1.2e-68 231.8 7.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI42025.1 - 6e-22 77.8 50.5 1e-17 63.9 14.3 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 KPI42025.1 - 6.6e-06 24.7 3.8 6.6e-06 24.7 2.7 3.1 1 1 1 3 3 3 2 MFS/sugar transport protein DUF3753 PF12575.3 KPI42025.1 - 4 7.2 5.2 25 4.7 0.3 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3753) YfiO PF13525.1 KPI42026.1 - 0.0061 16.0 0.6 0.016 14.6 0.4 1.6 1 1 0 1 1 1 1 Outer membrane lipoprotein HMG_box PF00505.14 KPI42026.1 - 0.039 14.2 0.6 0.47 10.7 0.0 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box CHORD PF04968.7 KPI42026.1 - 0.05 13.8 0.7 0.05 13.8 0.5 2.4 2 0 0 2 2 2 0 CHORD Glyco_hydro_3 PF00933.16 KPI42028.1 - 2.1e-36 125.4 0.0 3.3e-27 95.2 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KPI42028.1 - 3e-10 39.9 0.0 6.8e-10 38.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain TGT PF01702.13 KPI42029.1 - 1.6e-42 145.4 0.0 2.1e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase ING PF12998.2 KPI42029.1 - 0.041 14.1 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Sugar_tr PF00083.19 KPI42030.1 - 1.5e-60 205.0 35.3 2.2e-35 122.1 8.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI42030.1 - 3.8e-26 91.6 23.5 3.8e-26 91.6 16.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily zinc_ribbon_6 PF14599.1 KPI42031.1 - 2.3e-21 75.3 0.7 2.3e-21 75.3 0.5 3.8 3 1 1 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 KPI42031.1 - 1.5e-15 57.1 18.7 1.5e-15 57.1 13.0 3.7 3 1 0 3 3 3 1 CHY zinc finger ADH_N PF08240.7 KPI42031.1 - 2.3e-07 30.5 1.5 2.3e-07 30.5 1.1 4.9 4 2 0 4 4 4 1 Alcohol dehydrogenase GroES-like domain zf-RING_2 PF13639.1 KPI42031.1 - 2.9e-06 26.9 10.0 2.9e-06 26.9 6.9 4.3 2 1 2 4 4 4 1 Ring finger domain ADH_zinc_N PF00107.21 KPI42031.1 - 4.8e-06 26.1 0.6 4.8e-06 26.1 0.4 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase zf-C3HC4_3 PF13920.1 KPI42031.1 - 2.1e-05 24.0 10.2 2.1e-05 24.0 7.1 6.0 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI42031.1 - 0.00026 20.9 10.3 0.00026 20.9 7.2 5.4 4 1 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI42031.1 - 0.00063 19.4 10.1 0.00063 19.4 7.0 5.8 4 2 1 5 5 5 1 zinc-RING finger domain zf-C2H2_4 PF13894.1 KPI42031.1 - 0.26 11.6 0.1 0.26 11.6 0.1 4.3 5 0 0 5 5 5 0 C2H2-type zinc finger Acetyltransf_1 PF00583.19 KPI42034.1 - 3.8e-10 39.6 0.0 5.7e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI42034.1 - 1.8e-09 37.6 0.0 2.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI42034.1 - 2.3e-08 34.1 0.0 9.1e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KPI42034.1 - 3e-07 30.1 0.0 5.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KPI42034.1 - 6.6e-06 26.0 0.0 1.6e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KPI42034.1 - 0.001 18.8 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KPI42034.1 - 0.0022 17.8 0.0 0.032 14.1 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KPI42034.1 - 0.012 15.2 0.1 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.1 KPI42035.1 - 2.8e-79 266.6 35.9 3.7e-79 266.2 24.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI42035.1 - 9.5e-15 53.8 31.1 1.2e-14 53.5 21.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4131 PF13567.1 KPI42035.1 - 7.8 5.8 17.3 0.58 9.5 2.3 3.7 2 2 0 3 3 3 0 Domain of unknown function (DUF4131) Fungal_trans_2 PF11951.3 KPI42036.1 - 2.4e-26 92.2 1.8 1e-24 86.9 1.3 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain PfkB PF00294.19 KPI42037.1 - 2.7e-41 141.6 1.9 3.4e-41 141.3 1.3 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF3515 PF12028.3 KPI42038.1 - 0.084 12.1 0.2 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) TMEMspv1-c74-12 PF11044.3 KPI42038.1 - 0.12 11.8 0.2 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PLU-1 PF08429.6 KPI42039.1 - 4.2e-79 265.8 11.3 5.3e-78 262.2 5.3 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 KPI42039.1 - 1.2e-43 147.9 0.1 3.2e-43 146.5 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 KPI42039.1 - 1.3e-25 89.0 0.0 4e-25 87.4 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 KPI42039.1 - 2.3e-16 58.9 1.6 1.9e-15 56.0 0.1 2.7 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.11 KPI42039.1 - 6.2e-12 45.3 7.0 1.3e-11 44.4 4.9 1.6 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.24 KPI42039.1 - 2.5e-07 30.2 9.1 2.5e-07 30.2 6.3 3.4 3 0 0 3 3 3 1 PHD-finger F_bP_aldolase PF01116.15 KPI42040.1 - 3.5e-82 275.7 0.0 3.9e-82 275.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.13 KPI42040.1 - 0.027 13.4 0.1 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotriesterase family NAD_binding_4 PF07993.7 KPI42041.1 - 7.8e-33 113.4 0.0 1.2e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein DHQ_synthase PF01761.15 KPI42041.1 - 2.3e-32 111.9 0.0 6.9e-30 103.8 0.0 2.4 2 0 0 2 2 2 2 3-dehydroquinate synthase AMP-binding PF00501.23 KPI42041.1 - 1.3e-27 96.3 0.0 1.9e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KPI42041.1 - 4.1e-10 39.5 0.0 1.5e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KPI42041.1 - 3.4e-06 27.2 0.0 9.3e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Fe-ADH_2 PF13685.1 KPI42041.1 - 1.3e-05 24.6 0.0 0.001 18.4 0.0 3.2 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase KR PF08659.5 KPI42041.1 - 0.00066 19.3 2.0 0.045 13.4 0.0 2.8 3 0 0 3 3 3 1 KR domain GH3 PF03321.8 KPI42041.1 - 0.0069 14.9 0.0 0.011 14.2 0.0 1.2 1 0 0 1 1 1 1 GH3 auxin-responsive promoter Semialdhyde_dh PF01118.19 KPI42041.1 - 0.049 13.9 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KPI42041.1 - 0.18 10.4 0.0 2.3 6.8 0.0 2.2 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TRI12 PF06609.8 KPI42044.1 - 1.4e-73 248.0 19.7 1.9e-73 247.6 13.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI42044.1 - 1.2e-19 70.2 36.0 1.2e-19 70.2 25.0 3.4 2 1 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI42044.1 - 3e-10 39.2 12.0 3e-10 39.2 8.3 3.6 3 1 1 4 4 4 2 Sugar (and other) transporter MFS_1_like PF12832.2 KPI42044.1 - 0.00031 20.4 0.7 0.067 12.9 0.1 3.5 2 1 0 2 2 2 1 MFS_1 like family Pox_A14 PF05767.7 KPI42044.1 - 0.074 13.0 0.2 0.074 13.0 0.1 3.1 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 DUF4097 PF13349.1 KPI42044.1 - 0.099 12.1 0.5 2.2 7.7 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) MFS_1 PF07690.11 KPI42047.1 - 3.1e-32 111.6 29.5 3.1e-32 111.6 20.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Acyl-CoA_dh_1 PF00441.19 KPI42048.1 - 4.6e-28 98.2 2.5 7.3e-28 97.5 1.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PAN_1 PF00024.21 KPI42048.1 - 2.5e-09 36.7 11.2 0.0021 17.7 0.2 3.4 3 0 0 3 3 3 3 PAN domain Acyl-CoA_dh_2 PF08028.6 KPI42048.1 - 1.3e-05 25.4 1.6 2.6e-05 24.4 1.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PAN_4 PF14295.1 KPI42048.1 - 0.00027 20.5 23.3 0.13 11.9 1.9 4.3 3 2 1 4 4 4 3 PAN domain stn_TNFRSF12A PF12191.3 KPI42048.1 - 0.021 14.8 1.8 6.8 6.7 0.7 2.7 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain EphA2_TM PF14575.1 KPI42048.1 - 0.039 14.3 0.0 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 KPI42048.1 - 0.053 12.8 0.3 0.11 11.7 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PAN_3 PF08277.7 KPI42048.1 - 0.7 9.5 6.9 2.7 7.6 0.2 2.8 3 0 0 3 3 3 0 PAN-like domain FAT PF02259.18 KPI42049.1 - 3.9e-74 249.7 5.9 7.6e-74 248.7 4.1 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KPI42049.1 - 2.5e-25 89.3 0.1 7.6e-25 87.7 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GreA_GreB_N PF03449.10 KPI42050.1 - 0.0024 17.8 0.3 0.0049 16.8 0.2 1.5 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal DUF2993 PF11209.3 KPI42050.1 - 0.096 12.5 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2993) APC_CDC26 PF10471.4 KPI42050.1 - 1.2 9.9 8.7 0.13 12.9 0.9 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 p450 PF00067.17 KPI42051.1 - 3.3e-39 134.7 0.2 4.2e-39 134.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KPI42053.1 - 4.3e-24 84.7 0.0 6.9e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI42053.1 - 9.4e-08 31.8 8.9 1.7e-07 31.0 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBM_1 PF00734.13 KPI42054.1 - 3.8e-12 45.6 10.3 1.7e-11 43.5 7.1 2.3 1 0 0 1 1 1 1 Fungal cellulose binding domain DPBB_1 PF03330.13 KPI42054.1 - 7.7e-05 22.6 0.3 0.00027 20.8 0.1 2.1 1 1 1 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel ECH PF00378.15 KPI42056.1 - 6e-46 156.5 0.0 1.5e-45 155.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SnoaL PF07366.7 KPI42056.1 - 0.096 12.2 0.2 0.3 10.6 0.1 1.8 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase TAFII28 PF04719.9 KPI42058.1 - 2e-13 49.9 0.8 6.3e-13 48.3 0.4 1.9 2 0 0 2 2 2 1 hTAFII28-like protein conserved region Daxx PF03344.10 KPI42058.1 - 0.83 8.0 10.4 0.0099 14.4 2.0 1.5 2 0 0 2 2 2 0 Daxx Family Cytochrom_B561 PF03188.11 KPI42059.1 - 3.1e-07 30.2 7.3 5.6e-07 29.4 5.0 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2668 PF10873.3 KPI42059.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) DUF2427 PF10348.4 KPI42059.1 - 4.5 6.8 7.1 25 4.4 4.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) Amidase PF01425.16 KPI42060.1 - 6.4e-86 288.9 0.0 7.6e-86 288.6 0.0 1.1 1 0 0 1 1 1 1 Amidase SGL PF08450.7 KPI42061.1 - 7.2e-12 45.2 0.0 1.9e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 KPI42061.1 - 0.00012 22.0 0.0 0.00038 20.4 0.0 1.9 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 KPI42061.1 - 0.009 15.9 0.0 0.039 13.9 0.0 2.3 1 0 0 1 1 1 1 Arylesterase DUF2012 PF09430.5 KPI42062.1 - 1.7e-10 40.8 0.0 2.5e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) Ammonium_transp PF00909.16 KPI42064.1 - 3.7e-116 387.8 30.3 4.3e-116 387.6 21.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4395 PF14340.1 KPI42064.1 - 0.0043 17.1 2.0 0.0043 17.1 1.4 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4395) UPF0029 PF01205.14 KPI42065.1 - 1.3e-17 63.4 0.1 5.7e-17 61.3 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 Erythro_esteras PF05139.9 KPI42065.1 - 0.99 8.5 4.5 0.52 9.4 1.5 1.6 2 0 0 2 2 2 0 Erythromycin esterase DUF3245 PF11595.3 KPI42066.1 - 0.017 15.3 0.4 0.031 14.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Kelch_5 PF13854.1 KPI42067.1 - 1.9e-12 46.8 5.4 1.1e-08 34.8 0.1 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 KPI42067.1 - 1.3e-08 34.7 6.4 0.04 14.1 0.1 5.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.1 KPI42067.1 - 2e-07 30.6 2.8 1.1 9.1 0.1 5.1 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 KPI42067.1 - 7.6e-07 29.0 0.6 1.5 9.0 0.0 5.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 KPI42067.1 - 2.1e-05 24.1 4.6 1.1 9.1 0.0 4.6 4 1 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 KPI42067.1 - 0.00017 21.0 3.3 3.3 7.3 0.0 4.4 4 0 0 4 4 4 1 Kelch motif SKG6 PF08693.5 KPI42067.1 - 0.0058 15.9 1.0 0.015 14.6 0.7 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 KPI42067.1 - 0.014 14.8 0.1 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 GTP_EFTU PF00009.22 KPI42068.1 - 9.3e-31 106.7 0.0 5.1e-30 104.3 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KPI42068.1 - 2.3e-16 59.6 0.1 6e-16 58.2 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KPI42068.1 - 1.8e-14 53.6 2.6 5.4e-10 39.2 0.1 3.2 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KPI42068.1 - 1e-06 28.6 0.0 3.1e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KPI42068.1 - 5e-05 22.8 0.1 0.00016 21.2 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 KPI42068.1 - 0.0013 19.1 1.1 0.0036 17.7 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein ATP_bind_1 PF03029.12 KPI42068.1 - 0.0089 15.5 0.0 0.027 14.0 0.0 1.9 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Peptidase_M20 PF01546.23 KPI42069.1 - 1.9e-20 73.2 0.3 2.7e-20 72.6 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KPI42069.1 - 2.2e-14 53.1 0.0 4.6e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain MIP PF00230.15 KPI42070.1 - 1.1e-41 142.7 4.3 1.5e-41 142.3 3.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Sugar_tr PF00083.19 KPI42071.1 - 4.2e-60 203.5 19.2 7e-59 199.5 13.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI42071.1 - 6.8e-19 67.7 19.0 6.8e-19 67.7 13.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily CCSMST1 PF15013.1 KPI42071.1 - 0.59 10.0 7.5 13 5.8 2.0 2.8 2 0 0 2 2 2 0 CCSMST1 family TRI12 PF06609.8 KPI42072.1 - 6.2e-43 146.8 26.3 7.6e-43 146.5 18.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI42072.1 - 9.3e-21 73.9 53.4 9.3e-21 73.9 37.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI42072.1 - 3.3e-12 45.7 12.6 3.3e-12 45.7 8.7 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter Carn_acyltransf PF00755.15 KPI42073.1 - 1.4e-166 555.0 0.0 5.3e-150 500.3 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase UPF0020 PF01170.13 KPI42075.1 - 2.1e-12 46.9 0.0 6.5e-12 45.3 0.0 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KPI42075.1 - 1.4e-09 37.9 0.0 3.8e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 KPI42075.1 - 0.0027 17.2 0.0 0.0088 15.5 0.0 1.7 2 0 0 2 2 2 1 DNA methylase Methyltransf_15 PF09445.5 KPI42075.1 - 0.12 11.8 0.1 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Tubulin PF00091.20 KPI42076.1 - 8.6e-52 176.0 0.0 1.5e-33 116.4 0.0 2.3 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KPI42076.1 - 3.2e-49 166.1 0.1 5.3e-49 165.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KPI42076.1 - 0.0029 17.1 0.0 0.0087 15.5 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain DNA_RNApol_7kD PF03604.8 KPI42077.1 - 0.011 15.2 0.1 0.011 15.2 0.1 1.6 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DUF2296 PF10058.4 KPI42077.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) MIP PF00230.15 KPI42080.1 - 2.4e-49 167.8 10.7 3.1e-49 167.4 7.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein ATP-grasp_4 PF13535.1 KPI42081.1 - 7.1e-09 35.6 0.0 1.2e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KPI42081.1 - 4.1e-05 22.4 0.3 8.2e-05 21.4 0.2 1.5 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon MAP65_ASE1 PF03999.7 KPI42082.1 - 0.058 11.9 4.1 0.066 11.8 2.8 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF605 PF04652.11 KPI42082.1 - 1 8.7 15.2 1.2 8.4 10.5 1.1 1 0 0 1 1 1 0 Vta1 like adh_short_C2 PF13561.1 KPI42083.1 - 5.4e-16 59.0 0.0 6.5e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI42083.1 - 5e-11 42.7 0.9 6.3e-11 42.4 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.14 KPI42083.1 - 0.00026 20.1 0.2 0.00048 19.2 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 KPI42083.1 - 0.00068 19.8 0.7 0.001 19.3 0.1 1.5 2 0 0 2 2 1 1 Putative NAD(P)-binding Eno-Rase_NADH_b PF12242.3 KPI42083.1 - 0.0017 18.0 0.9 0.0035 17.1 0.6 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TrkA_N PF02254.13 KPI42083.1 - 0.002 18.0 0.1 0.04 13.9 0.1 2.2 2 0 0 2 2 2 1 TrkA-N domain KR PF08659.5 KPI42083.1 - 0.0028 17.3 0.1 0.005 16.5 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI42083.1 - 0.0087 16.0 0.3 0.016 15.2 0.2 1.5 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KPI42083.1 - 0.01 14.8 0.4 0.019 13.9 0.2 1.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase ApbA PF02558.11 KPI42083.1 - 0.017 14.5 0.2 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KPI42083.1 - 0.039 13.6 0.7 0.088 12.4 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KPI42083.1 - 0.053 13.6 0.2 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.16 KPI42083.1 - 0.058 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.22 KPI42083.1 - 0.058 13.8 1.3 0.1 13.0 0.4 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.16 KPI42083.1 - 0.066 12.7 0.2 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase FAD_binding_3 PF01494.14 KPI42083.1 - 0.085 11.8 0.5 0.12 11.4 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 KPI42083.1 - 0.098 12.7 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KPI42083.1 - 0.15 11.4 0.3 0.23 10.8 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.9 KPI42083.1 - 0.72 9.7 3.9 0.91 9.3 2.6 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 KPI42084.1 - 8.9e-21 73.9 20.7 9.1e-20 70.6 8.8 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF4118 PF13493.1 KPI42084.1 - 0.0072 16.5 2.8 0.0072 16.5 1.9 3.9 5 0 0 5 5 5 1 Domain of unknown function (DUF4118) BT1 PF03092.11 KPI42084.1 - 0.011 14.4 5.6 0.075 11.7 0.1 2.3 2 0 0 2 2 2 0 BT1 family Sulf_transp PF04143.9 KPI42085.1 - 6.2e-14 51.7 27.7 2.7e-08 33.7 8.4 5.4 5 1 1 6 6 6 2 Sulphur transport DUF4341 PF14241.1 KPI42085.1 - 0.00016 21.2 4.3 0.00016 21.2 3.0 4.3 4 1 0 4 4 4 1 Domain of unknown function (DUF4341) p450 PF00067.17 KPI42086.1 - 1.7e-73 247.7 0.0 2e-73 247.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HATPase_c PF02518.21 KPI42087.1 - 3.1e-29 100.9 0.0 1.1e-28 99.2 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KPI42087.1 - 9.2e-21 73.9 0.1 2.1e-20 72.8 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KPI42087.1 - 1.2e-19 70.1 0.0 6.4e-19 67.7 0.0 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 KPI42087.1 - 1.8e-12 47.6 0.0 6.5e-12 45.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain GAF_2 PF13185.1 KPI42087.1 - 2.7e-12 47.3 0.1 8.4e-12 45.8 0.1 1.8 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 KPI42087.1 - 1.2e-07 31.8 0.0 2.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 KPI42087.1 - 8.7e-06 25.9 0.1 2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 KPI42087.1 - 0.00025 20.2 0.0 0.00054 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain HATPase_c_3 PF13589.1 KPI42087.1 - 0.00063 19.4 0.1 0.0019 17.8 0.0 1.9 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_12 PF13424.1 KPI42087.1 - 0.0023 17.8 5.4 0.013 15.3 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat GRIP PF01465.15 KPI42087.1 - 0.053 13.0 0.0 6.4 6.3 0.0 2.9 2 0 0 2 2 2 0 GRIP domain NACHT PF05729.7 KPI42087.1 - 0.097 12.3 0.0 0.34 10.5 0.0 2.1 1 1 0 1 1 1 0 NACHT domain Glycos_transf_3 PF00591.16 KPI42088.1 - 5.2e-63 212.7 0.0 8.7e-50 169.4 0.0 2.2 1 1 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KPI42088.1 - 1.7e-06 27.5 0.0 3.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain HEAT_2 PF13646.1 KPI42088.1 - 0.11 12.7 0.1 0.27 11.5 0.1 1.7 1 0 0 1 1 1 0 HEAT repeats Acetate_kinase PF00871.12 KPI42089.1 - 7.9e-97 324.2 0.0 9.3e-97 323.9 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family NUDIX PF00293.23 KPI42090.1 - 1.1e-16 60.6 0.1 2e-16 59.8 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 KPI42090.1 - 1.5e-08 34.9 0.0 3.6e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 KPI42090.1 - 9.3e-07 28.2 0.7 1.6e-06 27.4 0.5 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Sugar_tr PF00083.19 KPI42091.1 - 2.1e-48 165.0 19.1 4.4e-33 114.5 6.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI42091.1 - 5.1e-18 64.9 41.2 7.1e-16 57.8 15.4 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Viral_Beta_CD PF04530.7 KPI42091.1 - 0.42 10.7 1.9 0.89 9.7 0.7 1.9 2 0 0 2 2 2 0 Viral Beta C/D like family Abhydrolase_6 PF12697.2 KPI42092.1 - 1.3e-17 64.4 0.5 2.3e-17 63.6 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI42092.1 - 1.1e-07 31.6 1.2 2.4e-07 30.5 0.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI42092.1 - 0.00072 19.1 5.3 0.00072 19.1 3.7 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold GHMP_kinases_C PF08544.8 KPI42092.1 - 0.015 15.5 0.8 0.064 13.4 0.5 2.1 1 1 1 2 2 2 0 GHMP kinases C terminal tRNA-synt_1c PF00749.16 KPI42093.1 - 1e-82 277.3 0.0 1.6e-82 276.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KPI42093.1 - 2.5e-20 72.8 1.0 4.6e-20 72.0 0.7 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Peptidase_S15 PF02129.13 KPI42094.1 - 2.5e-26 92.6 0.1 3e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 KPI42094.1 - 0.0011 18.8 0.7 0.002 18.0 0.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KPI42094.1 - 0.037 12.5 0.0 3.7 5.9 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DIOX_N PF14226.1 KPI42096.1 - 1.4e-23 83.5 0.0 2.5e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI42096.1 - 1.3e-19 70.3 0.0 3.7e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily NOB1_Zn_bind PF08772.6 KPI42097.1 - 1.1e-30 105.2 2.5 1.8e-30 104.5 1.7 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 KPI42097.1 - 4.1e-05 23.3 5.2 4.1e-05 23.3 3.6 1.9 1 1 0 1 1 1 1 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 KPI42097.1 - 0.061 12.8 3.1 0.063 12.7 0.6 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Pox_A28 PF04584.9 KPI42098.1 - 0.038 13.8 0.1 0.054 13.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A28 family Radial_spoke_3 PF06098.6 KPI42099.1 - 2.6 6.9 13.3 5.1 6.0 9.2 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 Ribosomal_L10 PF00466.15 KPI42100.1 - 0.0014 18.4 0.0 0.011 15.6 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L10 BatD PF13584.1 KPI42101.1 - 0.017 13.7 0.0 0.02 13.5 0.0 1.0 1 0 0 1 1 1 0 Oxygen tolerance YfhO PF09586.5 KPI42101.1 - 0.022 12.8 0.0 0.028 12.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2873 PF11395.3 KPI42101.1 - 4 7.0 5.7 6 6.5 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2873) WD40 PF00400.27 KPI42102.1 - 3.1e-34 115.6 10.8 8e-09 35.0 0.4 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 KPI42102.1 - 5.4e-05 22.9 0.2 4.9 6.9 0.0 4.6 3 1 2 5 5 5 2 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 KPI42102.1 - 0.00056 19.4 2.4 0.00061 19.3 0.6 1.8 1 1 1 2 2 2 1 PQQ-like domain Nup160 PF11715.3 KPI42102.1 - 0.0012 17.0 3.2 0.88 7.6 0.1 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PQQ_3 PF13570.1 KPI42102.1 - 0.0014 18.7 6.6 2 8.8 0.0 4.8 6 0 0 6 6 6 1 PQQ-like domain Cytochrom_D1 PF02239.11 KPI42102.1 - 0.0095 14.2 0.2 0.051 11.8 0.1 1.9 1 1 1 2 2 2 1 Cytochrome D1 heme domain Ribonuc_L-PSP PF01042.16 KPI42103.1 - 2.9e-19 69.0 0.0 3.5e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Asp PF00026.18 KPI42104.1 - 8.2e-15 54.8 0.1 6e-14 52.0 0.1 1.9 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KPI42104.1 - 0.0001 22.2 0.1 0.0008 19.3 0.1 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KPI42104.1 - 0.0042 17.5 0.2 0.85 10.1 0.0 3.0 2 1 0 2 2 2 1 Aspartyl protease RVP PF00077.15 KPI42104.1 - 0.031 14.1 0.0 5.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KPI42104.1 - 0.11 12.3 0.0 6.7 6.6 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease MFS_1 PF07690.11 KPI42105.1 - 8.3e-27 93.8 27.6 5.3e-26 91.1 19.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Prok-E2_C PF14459.1 KPI42105.1 - 0.22 11.6 1.1 1.1 9.3 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic E2 family C Fungal_trans PF04082.13 KPI42106.1 - 1.6e-11 43.6 0.1 3.2e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI42106.1 - 1.8e-08 34.1 11.0 3.5e-08 33.2 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 KPI42107.1 - 2.6e-81 273.1 0.0 3.3e-81 272.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme RICTOR_N PF14664.1 KPI42107.1 - 0.11 11.0 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term SelR PF01641.13 KPI42108.1 - 0.064 12.9 0.2 0.099 12.3 0.1 1.2 1 0 0 1 1 1 0 SelR domain MFS_1 PF07690.11 KPI42109.1 - 5.3e-44 150.3 39.0 1.5e-41 142.3 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI42109.1 - 6.9e-09 34.5 29.3 3e-05 22.6 8.2 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 KPI42109.1 - 0.004 16.9 6.2 0.005 16.6 0.6 3.5 5 0 0 5 5 5 1 MFS_1 like family Amidohydro_2 PF04909.9 KPI42110.1 - 4.1e-20 72.4 1.6 5.1e-20 72.1 1.1 1.1 1 0 0 1 1 1 1 Amidohydrolase SAM_decarbox PF01536.11 KPI42112.1 - 9.8e-87 290.7 0.0 3e-85 285.7 0.0 2.2 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase PHAT PF09246.5 KPI42112.1 - 0.041 13.4 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 PHAT UMP1 PF05348.6 KPI42113.1 - 0.022 14.7 0.4 0.039 13.9 0.3 1.4 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 Nop14 PF04147.7 KPI42113.1 - 0.21 9.4 8.6 0.29 9.0 6.0 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 KPI42113.1 - 0.44 9.2 14.5 0.044 12.5 4.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) PhzC-PhzF PF02567.11 KPI42115.1 - 1.5e-32 112.9 0.0 1e-31 110.2 0.0 1.9 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Mito_carr PF00153.22 KPI42117.1 - 1.8e-55 184.5 2.1 3.7e-18 65.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TPR_12 PF13424.1 KPI42118.1 - 2.2e-10 40.2 5.2 2e-06 27.6 0.0 4.7 3 1 0 4 4 4 1 Tetratricopeptide repeat AAA_19 PF13245.1 KPI42118.1 - 1.8e-05 24.4 0.0 6.3e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KPI42118.1 - 3.2e-05 23.9 5.4 5.9e-05 23.1 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain TPR_10 PF13374.1 KPI42118.1 - 3.5e-05 23.5 0.6 0.64 10.0 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.1 KPI42118.1 - 0.0004 20.5 0.7 0.0068 16.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 KPI42118.1 - 0.00046 19.8 0.0 0.0015 18.2 0.0 1.9 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 KPI42118.1 - 0.0008 18.4 0.1 0.0051 15.8 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) TPR_2 PF07719.12 KPI42118.1 - 0.0014 18.3 0.7 23 5.2 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat NB-ARC PF00931.17 KPI42118.1 - 0.0025 16.7 0.0 0.0061 15.4 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.24 KPI42118.1 - 0.0029 17.7 0.0 0.0086 16.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KPI42118.1 - 0.015 15.2 0.9 0.81 9.6 0.1 3.5 2 1 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 KPI42118.1 - 0.034 13.6 0.0 0.055 12.9 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TPR_7 PF13176.1 KPI42118.1 - 0.038 13.8 0.0 10 6.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat UPF0079 PF02367.12 KPI42118.1 - 0.091 12.3 0.0 12 5.5 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 KPI42118.1 - 0.095 11.9 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein MmgE_PrpD PF03972.9 KPI42119.1 - 1.9e-70 237.3 5.8 2.1e-70 237.1 4.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Vac_ImportDeg PF09783.4 KPI42120.1 - 6.9e-62 208.0 0.5 9.8e-62 207.5 0.3 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein adh_short PF00106.20 KPI42121.1 - 2.2e-11 43.9 0.0 3e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI42121.1 - 0.03 13.9 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 KR domain Zn_clus PF00172.13 KPI42122.1 - 1.5e-07 31.2 10.3 1.5e-07 31.2 7.1 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KPI42122.1 - 1.4e-05 23.8 0.0 2.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ResIII PF04851.10 KPI42123.1 - 3.4e-23 82.4 0.0 1.1e-22 80.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KPI42123.1 - 9.2e-15 54.2 0.1 2.4e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KPI42123.1 - 8.3e-13 48.1 0.0 1.8e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 KPI42123.1 - 0.00037 19.5 0.0 0.00076 18.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 KPI42123.1 - 0.029 13.9 0.4 0.74 9.3 0.0 2.9 2 2 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KPI42123.1 - 0.03 14.4 0.0 0.079 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 KPI42123.1 - 0.046 13.0 0.0 2.4 7.3 0.0 2.3 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain Peptidase_M24 PF00557.19 KPI42124.1 - 2.5e-36 125.2 0.0 3.8e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KPI42124.1 - 3.8e-08 33.8 0.0 7.1e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Myb_DNA-binding PF00249.26 KPI42125.1 - 0.0063 16.5 0.1 0.018 15.0 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Fungal_trans PF04082.13 KPI42126.1 - 7.1e-08 31.6 0.0 1.8e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI42126.1 - 6e-06 26.0 7.9 1.1e-05 25.2 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KPI42126.1 - 1.8 8.7 7.9 4.1 7.6 5.5 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region F-box-like PF12937.2 KPI42127.1 - 0.073 12.8 0.2 0.073 12.8 0.2 2.5 2 0 0 2 2 2 0 F-box-like F-box-like_2 PF13013.1 KPI42127.1 - 0.19 11.4 1.4 0.45 10.2 1.0 1.7 1 1 0 1 1 1 0 F-box-like domain Mid2 PF04478.7 KPI42128.1 - 0.0039 16.6 0.8 0.0062 15.9 0.6 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor STE2 PF02116.10 KPI42128.1 - 0.15 11.1 0.1 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR TMEM154 PF15102.1 KPI42128.1 - 0.69 9.6 4.5 2.1 8.0 3.1 1.8 1 1 0 1 1 1 0 TMEM154 protein family Glycophorin_A PF01102.13 KPI42128.1 - 0.74 9.5 5.5 0.65 9.7 2.6 1.8 1 1 0 1 1 1 0 Glycophorin A Pyr_redox_3 PF13738.1 KPI42129.1 - 1.2e-41 143.0 0.0 2e-41 142.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KPI42129.1 - 0.1 12.6 0.0 0.6 10.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pkinase PF00069.20 KPI42130.1 - 3.8e-10 39.3 0.0 1.7e-09 37.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Herpes_TAF50 PF03326.8 KPI42130.1 - 0.17 10.7 5.5 0.25 10.2 3.8 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF4407 PF14362.1 KPI42130.1 - 8.6 5.2 9.5 16 4.2 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L30 PF00327.15 KPI42131.1 - 3.6e-15 55.2 0.1 5e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e FAD_binding_3 PF01494.14 KPI42132.1 - 2.3e-12 46.6 0.0 4.8e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI42132.1 - 2.1e-08 33.5 0.2 1.5e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI42132.1 - 3.3e-07 30.3 1.2 2.6e-06 27.4 0.8 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI42132.1 - 4.6e-07 28.6 0.1 0.00054 18.5 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 KPI42132.1 - 9.1e-07 28.0 0.8 1.7e-06 27.1 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KPI42132.1 - 1.6e-06 28.0 0.2 3.8e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KPI42132.1 - 2.7e-06 26.5 0.0 4.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 KPI42132.1 - 3.3e-06 27.3 0.2 0.0025 18.2 0.0 2.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KPI42132.1 - 4.4e-06 26.0 0.1 6.7e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KPI42132.1 - 4.3e-05 22.5 0.1 7.1e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 KPI42132.1 - 0.00078 19.1 0.2 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KPI42132.1 - 0.021 13.9 0.2 0.047 12.7 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Fungal_trans PF04082.13 KPI42133.1 - 4.6e-06 25.7 0.1 7.3e-06 25.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI42133.1 - 0.00018 21.3 8.4 0.00037 20.3 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sen15 PF09631.5 KPI42134.1 - 1.4e-12 47.7 0.0 2.5e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Sen15 protein Zn_clus PF00172.13 KPI42136.1 - 3.6e-06 26.7 12.0 6.8e-06 25.8 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KPI42136.1 - 0.0083 14.7 0.7 0.014 13.9 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2231 PF09990.4 KPI42137.1 - 0.052 13.8 0.7 0.084 13.2 0.5 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2231) COPI_assoc PF08507.5 KPI42137.1 - 0.1 12.3 3.6 0.74 9.4 2.5 1.9 1 1 0 1 1 1 0 COPI associated protein NIL PF09383.5 KPI42137.1 - 0.11 12.0 0.2 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 NIL domain UPF0154 PF03672.8 KPI42137.1 - 0.13 11.9 1.0 2 8.1 0.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0154) Glycoprotein_B PF00606.13 KPI42137.1 - 0.24 9.3 1.0 0.25 9.3 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B HAP PF03866.8 KPI42137.1 - 0.54 10.0 3.9 0.65 9.7 2.7 1.2 1 0 0 1 1 1 0 Hydrophobic abundant protein (HAP) HATPase_c PF02518.21 KPI42138.1 - 5.1e-11 42.2 0.0 1.3e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.4 KPI42138.1 - 5.7e-06 25.9 0.0 9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c_3 PF13589.1 KPI42138.1 - 0.0002 21.0 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KPI42138.1 - 0.00053 19.7 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 2 Histidine kinase-like ATPase domain CAP PF00188.21 KPI42139.1 - 4.1e-21 75.7 3.4 7.9e-21 74.8 2.4 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF3446 PF11928.3 KPI42139.1 - 0.13 12.4 13.4 0.31 11.2 9.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) MSA-2c PF12238.3 KPI42139.1 - 0.79 9.3 7.9 1.2 8.7 5.5 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c p450 PF00067.17 KPI42140.1 - 4.6e-48 163.8 0.0 9.1e-48 162.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Thymidylate_kin PF02223.12 KPI42141.1 - 2.9e-42 144.1 0.0 3.4e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase CPT PF07931.7 KPI42141.1 - 0.0016 18.1 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Resolvase PF00239.16 KPI42141.1 - 0.0098 15.7 0.0 0.022 14.6 0.0 1.6 2 0 0 2 2 2 1 Resolvase, N terminal domain KTI12 PF08433.5 KPI42141.1 - 0.071 12.2 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Pga1 PF10333.4 KPI42142.1 - 0.00021 21.0 0.3 0.00065 19.4 0.0 1.8 2 0 0 2 2 2 1 GPI-Mannosyltransferase II co-activator Sugar_tr PF00083.19 KPI42143.1 - 4.6e-93 312.2 27.9 5.5e-93 311.9 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI42143.1 - 1e-16 60.6 37.6 5e-16 58.3 9.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.7 KPI42144.1 - 2.3e-16 59.5 1.0 4.7e-16 58.4 0.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI42144.1 - 6.1e-14 51.6 0.0 9.5e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KPI42144.1 - 0.00063 19.3 0.1 0.0013 18.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI42144.1 - 0.0011 19.5 0.1 0.002 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI42144.1 - 0.014 15.4 0.1 0.026 14.5 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KPI42144.1 - 0.028 14.7 0.1 0.069 13.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 KPI42144.1 - 0.035 13.7 0.0 0.27 10.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DUF4593 PF15263.1 KPI42144.1 - 0.04 13.8 1.8 0.074 12.9 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4593) TPMT PF05724.6 KPI42144.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.15 KPI42144.1 - 0.12 11.3 0.1 0.22 10.5 0.1 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase WD40 PF00400.27 KPI42145.1 - 2e-46 154.2 39.1 4e-11 42.3 0.1 11.7 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 KPI42145.1 - 7.8e-19 67.6 0.0 1.3e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family IKI3 PF04762.7 KPI42145.1 - 0.0037 15.1 0.0 1.9 6.1 0.0 2.8 2 1 1 3 3 3 2 IKI3 family Cytochrom_D1 PF02239.11 KPI42145.1 - 0.037 12.3 0.0 0.68 8.1 0.0 2.7 3 0 0 3 3 3 0 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 KPI42145.1 - 0.27 9.9 0.0 27 3.4 0.0 3.2 3 0 0 3 3 3 0 Coatomer WD associated region MFS_1 PF07690.11 KPI42146.1 - 7e-34 117.0 47.6 6e-32 110.7 22.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OAD_gamma PF04277.8 KPI42146.1 - 0.036 14.4 1.7 25 5.3 0.0 3.6 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF1446 PF07287.6 KPI42147.1 - 3.8e-128 426.9 0.0 4.6e-128 426.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Med6 PF04934.9 KPI42147.1 - 0.18 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 MED6 mediator sub complex component RmlD_sub_bind PF04321.12 KPI42148.1 - 3.6e-61 206.5 0.6 4.3e-61 206.3 0.4 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KPI42148.1 - 1.3e-29 103.3 0.1 1.6e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KPI42148.1 - 2.5e-12 46.2 0.4 1.3e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KPI42148.1 - 2.1e-11 44.1 3.8 8.6e-11 42.1 2.6 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KPI42148.1 - 3.5e-11 42.5 6.3 6.5e-10 38.3 0.5 3.3 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KPI42148.1 - 2.2e-09 36.4 0.2 7.7e-09 34.6 0.1 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KPI42148.1 - 1.6e-05 24.8 3.0 0.00059 19.7 2.1 2.5 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KPI42148.1 - 0.0028 16.9 0.2 0.048 12.9 0.0 2.3 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 KPI42148.1 - 0.015 14.9 2.3 2.4 7.7 1.6 2.4 1 1 0 1 1 1 0 KR domain Cation_ATPase_C PF00689.16 KPI42149.1 - 2.8 7.4 11.6 1.8 8.0 4.3 2.2 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus adh_short_C2 PF13561.1 KPI42150.1 - 5.7e-22 78.6 0.1 9.4e-22 77.9 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI42150.1 - 2.4e-17 63.3 1.0 4.4e-17 62.4 0.7 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI42150.1 - 2.9e-06 27.0 1.5 2.2e-05 24.1 1.0 2.0 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KPI42150.1 - 0.01 14.7 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PA PF02225.17 KPI42150.1 - 0.069 12.8 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 PA domain Sdh_cyt PF01127.17 KPI42151.1 - 2.6e-24 85.3 5.4 3.6e-24 84.9 3.7 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit adh_short_C2 PF13561.1 KPI42152.1 - 3.3e-30 105.6 0.1 3.8e-30 105.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI42152.1 - 6.9e-12 45.5 1.2 1.1e-11 44.9 0.9 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI42152.1 - 3.1e-05 23.7 0.3 6.2e-05 22.7 0.3 1.4 1 1 1 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 KPI42152.1 - 0.0075 16.0 0.3 0.017 14.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KPI42152.1 - 0.013 15.5 1.5 0.058 13.4 1.1 2.0 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 KPI42152.1 - 0.043 13.2 0.1 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KPI42152.1 - 0.096 12.7 0.0 0.4 10.7 0.0 2.0 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 KPI42152.1 - 0.12 11.4 0.3 0.44 9.6 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Gtr1_RagA PF04670.7 KPI42153.1 - 6.3e-90 300.3 0.0 8.1e-90 300.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KPI42153.1 - 4.8e-09 35.8 0.0 9.3e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KPI42153.1 - 2e-06 27.1 0.0 2.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KPI42153.1 - 3e-06 27.1 0.0 5.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KPI42153.1 - 7e-06 26.5 0.1 2.6e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 KPI42153.1 - 0.00099 18.5 0.0 0.0032 16.9 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KPI42153.1 - 0.0029 17.1 1.0 0.013 15.0 0.6 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KPI42153.1 - 0.011 15.9 0.0 0.026 14.8 0.0 1.7 2 0 0 2 2 2 0 ABC transporter SRPRB PF09439.5 KPI42153.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KPI42153.1 - 0.027 13.6 0.2 0.08 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF815 PF05673.8 KPI42153.1 - 0.028 13.3 0.1 0.056 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 KPI42153.1 - 0.042 13.2 0.1 0.11 11.8 0.1 1.9 2 1 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 KPI42153.1 - 0.065 13.2 0.2 0.15 11.9 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 KPI42153.1 - 0.068 12.2 0.7 0.12 11.4 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin AIG1 PF04548.11 KPI42153.1 - 0.08 12.0 0.3 0.21 10.6 0.2 1.9 1 1 0 1 1 1 0 AIG1 family Sigma54_activat PF00158.21 KPI42153.1 - 0.1 12.0 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain G-alpha PF00503.15 KPI42153.1 - 0.14 10.8 2.8 1.4 7.4 0.9 2.3 1 1 1 2 2 2 0 G-protein alpha subunit LCCL PF03815.14 KPI42154.1 - 1.1e-14 54.1 0.0 2e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 LCCL domain ADH_N PF08240.7 KPI42155.1 - 2.4e-21 75.5 3.8 4.5e-21 74.6 2.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI42155.1 - 2.4e-09 36.8 0.1 4.5e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase p450 PF00067.17 KPI42156.1 - 3.3e-21 75.3 0.0 1.4e-20 73.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 PepX_C PF08530.5 KPI42157.1 - 9.5e-28 97.5 0.1 1.2e-27 97.2 0.1 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Rad10 PF03834.9 KPI42158.1 - 7e-31 105.7 0.0 1.1e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 KPI42158.1 - 1.3e-06 28.4 0.0 2.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 KPI42158.1 - 0.0057 16.5 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.18 KPI42158.1 - 0.02 14.5 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif SART-1 PF03343.8 KPI42158.1 - 0.039 12.2 0.4 0.057 11.7 0.3 1.2 1 0 0 1 1 1 0 SART-1 family Zn_clus PF00172.13 KPI42159.1 - 4.4e-08 32.8 9.1 8.3e-08 32.0 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like_2 PF13013.1 KPI42160.1 - 0.0022 17.7 0.1 0.0064 16.1 0.0 1.8 2 0 0 2 2 2 1 F-box-like domain F-box-like PF12937.2 KPI42160.1 - 0.075 12.7 0.0 0.15 11.8 0.0 1.6 1 1 0 1 1 1 0 F-box-like Glyco_hydro_3 PF00933.16 KPI42161.1 - 3.7e-90 301.9 0.0 6.1e-90 301.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KPI42161.1 - 4.4e-51 173.5 1.5 3.6e-50 170.6 0.2 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KPI42161.1 - 1.5e-20 72.8 0.1 2.8e-20 72.0 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain CDC45 PF02724.9 KPI42162.1 - 6.1 4.7 6.3 8.1 4.3 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SAGA-Tad1 PF12767.2 KPI42162.1 - 7.7 6.0 13.1 1.5 8.4 4.1 2.1 1 1 1 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit EMP24_GP25L PF01105.19 KPI42164.1 - 4.1e-48 163.5 0.1 4.8e-48 163.2 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ACT_7 PF13840.1 KPI42165.1 - 5.7e-27 93.0 0.0 9.6e-16 57.0 0.0 2.8 2 1 0 2 2 2 2 ACT domain Milton PF12448.3 KPI42165.1 - 0.12 12.5 0.9 0.18 12.0 0.1 1.6 2 0 0 2 2 2 0 Kinesin associated protein p450 PF00067.17 KPI42167.1 - 4.2e-51 173.9 0.0 5.2e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 XFP_N PF09364.5 KPI42168.1 - 1.4e-146 487.9 1.2 4.8e-145 482.8 0.8 2.1 1 1 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 KPI42168.1 - 6.8e-69 231.0 0.1 1.1e-68 230.3 0.1 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 KPI42168.1 - 4.3e-65 218.9 0.0 7.1e-65 218.2 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 KPI42168.1 - 0.028 13.9 0.3 0.17 11.4 0.1 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain AA_permease PF00324.16 KPI42169.1 - 2.6e-107 359.1 36.5 3.1e-107 358.8 25.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI42169.1 - 3.3e-16 58.8 40.4 4.7e-16 58.3 28.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 KPI42169.1 - 0.0061 16.2 2.0 0.0061 16.2 1.4 4.1 4 1 1 5 5 5 1 Domain of unknown function (DUF1772) Dioxygenase_C PF00775.16 KPI42170.1 - 1.5e-49 167.7 0.0 2.6e-49 166.9 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Fungal_trans PF04082.13 KPI42170.1 - 1e-12 47.4 0.0 2.4e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dioxygenase_N PF04444.9 KPI42170.1 - 2e-12 46.9 0.1 4.6e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Catechol dioxygenase N terminus MTHFR PF02219.12 KPI42172.1 - 4.5e-75 252.3 0.0 2.8e-73 246.5 0.0 2.1 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase AAA PF00004.24 KPI42173.1 - 5.2e-16 59.0 0.0 3.2e-15 56.4 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 KPI42173.1 - 6.4e-14 51.9 1.4 1.6e-13 50.6 0.0 2.2 2 0 0 2 2 2 1 BCS1 N terminal AAA_16 PF13191.1 KPI42173.1 - 3.9e-05 23.7 0.0 0.00023 21.2 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KPI42173.1 - 0.0013 19.4 4.3 0.011 16.5 3.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KPI42173.1 - 0.0019 17.6 0.0 0.0049 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KPI42173.1 - 0.0039 16.8 2.3 0.13 11.7 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 KPI42173.1 - 0.0042 16.7 0.8 0.013 15.1 0.6 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KPI42173.1 - 0.0098 16.1 0.2 0.048 13.9 0.0 2.0 2 1 0 2 2 1 1 ABC transporter AAA_22 PF13401.1 KPI42173.1 - 0.011 15.9 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KPI42173.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Spore_coat_CotO PF14153.1 KPI42173.1 - 0.015 14.7 8.8 0.028 13.8 6.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO RuvB_N PF05496.7 KPI42173.1 - 0.021 13.8 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KPI42173.1 - 0.022 14.9 0.0 0.086 13.0 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 KPI42173.1 - 0.028 14.1 0.0 0.073 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PPV_E1_C PF00519.12 KPI42173.1 - 0.034 12.7 0.0 0.055 12.0 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase DUF815 PF05673.8 KPI42173.1 - 0.052 12.4 0.0 0.12 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 KPI42173.1 - 0.053 12.3 0.0 0.11 11.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RP-C_C PF11800.3 KPI42173.1 - 0.065 12.9 2.0 0.15 11.7 1.4 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region AAA_33 PF13671.1 KPI42173.1 - 0.067 13.0 0.1 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 KPI42173.1 - 0.067 12.2 0.1 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.1 KPI42173.1 - 0.074 13.3 0.0 0.074 13.3 0.0 2.4 2 1 0 2 2 1 0 AAA domain DUF3987 PF13148.1 KPI42173.1 - 0.075 11.5 7.1 0.75 8.3 6.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) TIP49 PF06068.8 KPI42173.1 - 0.081 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus PBP1_TM PF14812.1 KPI42173.1 - 0.12 12.6 21.8 0.78 10.0 6.4 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_21 PF13304.1 KPI42173.1 - 0.12 12.2 0.4 0.28 11.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain ScpA_ScpB PF02616.9 KPI42173.1 - 0.13 11.8 6.7 0.25 10.8 4.6 1.4 1 0 0 1 1 1 0 ScpA/B protein AAA_23 PF13476.1 KPI42173.1 - 0.59 10.4 7.3 9.7 6.4 5.0 2.3 1 1 0 1 1 1 0 AAA domain LIP PF03583.9 KPI42174.1 - 1.5e-12 47.3 0.3 1.2e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_5 PF12695.2 KPI42174.1 - 4.2e-07 29.8 0.2 9.8e-07 28.6 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI42174.1 - 1e-05 25.5 5.1 3.6e-05 23.7 3.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 KPI42174.1 - 0.19 9.9 0.2 1.1 7.4 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF1295 PF06966.7 KPI42175.1 - 1.3e-21 76.9 2.8 1.4e-21 76.9 1.3 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 KPI42175.1 - 0.021 14.5 1.7 0.053 13.2 0.7 1.9 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase Fungal_trans_2 PF11951.3 KPI42176.1 - 0.00036 19.2 0.2 0.0012 17.4 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain F-box PF00646.28 KPI42177.1 - 1e-05 25.0 0.4 4.3e-05 23.0 0.3 2.1 1 0 0 1 1 1 1 F-box domain FAD_binding_4 PF01565.18 KPI42178.1 - 4.2e-17 61.9 3.2 1.2e-16 60.4 2.2 1.8 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 KPI42178.1 - 2e-10 40.4 0.0 3.5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF4066 PF13278.1 KPI42181.1 - 2.3e-20 72.5 0.1 1.4e-19 69.9 0.1 1.9 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KPI42181.1 - 4.7e-09 35.8 0.0 8.5e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family bZIP_1 PF00170.16 KPI42182.1 - 0.0013 18.6 6.0 0.0015 18.4 1.8 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KPI42182.1 - 5.4 6.9 10.4 1.2 8.9 2.0 2.3 1 1 0 2 2 2 0 Basic region leucine zipper DUF605 PF04652.11 KPI42185.1 - 1.5 8.1 13.9 1.7 7.9 9.6 1.1 1 0 0 1 1 1 0 Vta1 like RWD PF05773.17 KPI42186.1 - 4.2e-19 68.5 0.5 1.2e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 RWD domain adh_short PF00106.20 KPI42186.1 - 6.2e-18 65.2 0.4 1.5e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI42186.1 - 1.7e-14 54.1 0.0 9.4e-13 48.4 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI42186.1 - 0.0067 16.1 0.6 0.016 14.8 0.1 1.8 2 0 0 2 2 2 1 KR domain Acetyltransf_1 PF00583.19 KPI42187.1 - 4.1e-13 49.1 0.0 6.8e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI42187.1 - 4.6e-10 39.5 0.0 9.3e-10 38.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI42187.1 - 2.8e-06 27.4 0.0 3.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KPI42187.1 - 0.0017 18.1 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KPI42187.1 - 0.0027 17.4 0.0 0.0066 16.1 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein DIOX_N PF14226.1 KPI42188.1 - 8.3e-22 77.9 0.0 1.5e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI42188.1 - 3.4e-19 68.9 0.0 5.3e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Stb3 PF10330.4 KPI42189.1 - 1.2e-36 124.2 0.0 1.9e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein Pectate_lyase_3 PF12708.2 KPI42190.1 - 3.9e-70 236.4 16.8 8.2e-55 186.3 4.1 3.7 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KPI42190.1 - 8.9e-06 25.0 2.6 0.075 12.5 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Septin PF00735.13 KPI42191.1 - 2e-114 381.3 0.2 2.7e-114 380.9 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KPI42191.1 - 1.6e-07 31.3 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KPI42191.1 - 1.1e-05 24.7 0.0 2.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KPI42191.1 - 7.3e-05 22.2 0.3 7.3e-05 22.2 0.2 2.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 KPI42191.1 - 0.00041 20.7 3.9 0.11 12.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KPI42191.1 - 0.0013 19.2 0.1 0.0042 17.5 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 KPI42191.1 - 0.0026 17.4 0.1 0.0046 16.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KPI42191.1 - 0.0028 17.8 0.1 0.01 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.11 KPI42191.1 - 0.005 15.9 0.0 0.0098 15.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 KPI42191.1 - 0.01 14.7 0.0 0.017 13.9 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Ras PF00071.17 KPI42191.1 - 0.011 15.1 0.3 0.036 13.4 0.1 2.0 2 0 0 2 2 2 0 Ras family Pox_A32 PF04665.7 KPI42191.1 - 0.019 14.2 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 KPI42191.1 - 0.022 14.2 1.6 0.026 14.0 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 KPI42191.1 - 0.027 14.7 0.3 0.094 13.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter T2SE PF00437.15 KPI42191.1 - 0.035 12.9 0.5 0.076 11.9 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.7 KPI42191.1 - 0.041 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.9 KPI42191.1 - 0.043 12.8 0.9 0.054 12.4 0.6 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.1 KPI42191.1 - 0.045 13.7 0.8 0.34 10.8 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain Dynamin_N PF00350.18 KPI42191.1 - 0.049 13.4 5.8 0.47 10.2 0.1 2.8 2 1 1 3 3 3 0 Dynamin family RNA_helicase PF00910.17 KPI42191.1 - 0.085 13.0 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PduV-EutP PF10662.4 KPI42191.1 - 0.1 12.1 1.2 2.6 7.5 0.3 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 KPI42191.1 - 0.11 11.8 0.2 0.34 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KPI42191.1 - 0.15 11.5 0.8 7.3 6.0 0.1 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RRM_1 PF00076.17 KPI42193.1 - 9.6e-16 57.1 0.0 1.3e-06 27.9 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI42193.1 - 5e-13 48.8 0.0 3.8e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI42193.1 - 4.1e-10 39.3 0.0 1.7e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_25 PF13649.1 KPI42193.1 - 0.13 12.6 0.1 0.35 11.2 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Asp_Glu_race PF01177.17 KPI42194.1 - 3.8e-06 26.9 0.0 0.0013 18.6 0.0 2.2 1 1 1 2 2 2 2 Asp/Glu/Hydantoin racemase Aldo_ket_red PF00248.16 KPI42195.1 - 2.4e-51 174.2 0.0 7.2e-50 169.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Rrn6 PF10214.4 KPI42196.1 - 1.7e-43 148.8 0.0 2.8e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Tim54 PF11711.3 KPI42197.1 - 4.1e-125 417.3 0.1 4.8e-125 417.1 0.1 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF3464 PF11947.3 KPI42197.1 - 7.7 5.9 6.1 1.3 8.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3464) RRM_5 PF13893.1 KPI42199.1 - 5.8e-06 26.0 0.1 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KPI42199.1 - 6.1e-06 25.7 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI42199.1 - 0.0024 17.7 0.0 0.0059 16.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 KPI42199.1 - 0.0099 16.1 0.0 0.41 10.9 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Aminotran_1_2 PF00155.16 KPI42201.1 - 2e-06 26.9 0.0 8.7e-06 24.9 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Tannase PF07519.6 KPI42201.1 - 0.034 12.8 0.0 0.056 12.1 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase IBR PF01485.16 KPI42202.1 - 9.7e-09 34.9 39.4 9.6e-07 28.5 8.8 3.8 2 2 1 3 3 3 2 IBR domain zf-RING_2 PF13639.1 KPI42202.1 - 0.00045 19.9 7.1 0.00045 19.9 4.9 4.9 3 1 1 4 4 4 2 Ring finger domain zf-RING_5 PF14634.1 KPI42202.1 - 0.00052 19.6 7.2 0.00052 19.6 5.0 4.5 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KPI42202.1 - 0.0084 15.7 7.0 0.0084 15.7 4.9 4.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI42202.1 - 0.028 14.4 7.1 0.028 14.4 4.9 4.8 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KPI42202.1 - 8.3 6.2 15.2 0.38 10.5 3.2 2.9 2 0 0 2 2 2 0 RING-type zinc-finger PAM2 PF07145.10 KPI42203.1 - 0.00076 18.8 18.2 0.14 11.6 0.1 5.2 5 0 0 5 5 5 3 Ataxin-2 C-terminal region Rootletin PF15035.1 KPI42203.1 - 0.0022 18.0 24.2 0.0022 18.0 16.8 6.2 4 2 2 6 6 6 3 Ciliary rootlet component, centrosome cohesion Reo_sigmaC PF04582.7 KPI42203.1 - 3.1 6.9 16.8 0.041 13.0 3.1 3.2 2 1 0 3 3 3 0 Reovirus sigma C capsid protein Zn_clus PF00172.13 KPI42204.1 - 1.5e-05 24.7 14.2 2.6e-05 24.0 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF500 PF04366.7 KPI42205.1 - 7.2e-41 138.5 0.1 1.2e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) Herpes_pp85 PF04637.7 KPI42205.1 - 0.2 9.8 0.4 0.3 9.3 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) TGS PF02824.16 KPI42206.1 - 2.3e-20 72.1 0.0 4e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KPI42206.1 - 3.3e-20 72.1 0.0 7.2e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KPI42206.1 - 3.8e-14 52.2 0.0 6.2e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KPI42206.1 - 0.0001 22.1 0.2 0.15 11.8 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KPI42206.1 - 0.0019 18.6 0.0 0.0051 17.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 KPI42206.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family ArgK PF03308.11 KPI42206.1 - 0.049 12.4 0.1 0.096 11.4 0.1 1.5 1 0 0 1 1 1 0 ArgK protein MCM PF00493.18 KPI42206.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family AAA_17 PF13207.1 KPI42206.1 - 0.22 12.3 1.2 1.2 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain OsmC PF02566.14 KPI42207.1 - 9.9e-19 67.3 0.0 1.9e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 OsmC-like protein adh_short_C2 PF13561.1 KPI42208.1 - 5.8e-25 88.4 0.0 6.5e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI42208.1 - 4.5e-13 49.4 0.0 5.9e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI42208.1 - 3.1e-07 30.2 0.0 4.6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI42208.1 - 7e-05 22.3 0.0 0.00038 19.9 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 KPI42208.1 - 0.00015 21.9 0.0 0.00062 19.9 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_10 PF13460.1 KPI42208.1 - 0.0012 18.9 0.2 0.0031 17.5 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KPI42208.1 - 0.013 14.5 0.0 0.35 9.9 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.21 KPI42208.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 KPI42208.1 - 0.019 14.6 0.1 0.043 13.4 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.8 KPI42208.1 - 0.062 12.5 0.2 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family YjeF_N PF03853.10 KPI42208.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus 2-Hacid_dh_C PF02826.14 KPI42208.1 - 0.084 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain INTS5_N PF14837.1 KPI42208.1 - 0.091 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus ApbA PF02558.11 KPI42208.1 - 0.098 12.0 0.1 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 KPI42208.1 - 0.12 12.8 0.3 0.51 10.7 0.0 2.2 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KPI42208.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Mg_trans_NIPA PF05653.9 KPI42209.1 - 3e-67 226.6 3.8 7.5e-64 215.5 1.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KPI42209.1 - 0.0002 21.5 0.1 0.0002 21.5 0.0 3.7 3 1 1 4 4 4 1 Multidrug resistance efflux transporter LysE PF01810.13 KPI42209.1 - 0.0079 15.4 1.6 0.0079 15.4 1.1 2.2 3 0 0 3 3 3 1 LysE type translocator LRR19-TM PF15176.1 KPI42209.1 - 0.015 14.9 0.0 7.5 6.2 0.0 2.7 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF914 PF06027.7 KPI42209.1 - 0.025 13.4 0.1 0.025 13.4 0.0 2.2 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF914) DUF2052 PF09747.4 KPI42210.1 - 2e-32 112.5 11.5 6.7e-32 110.8 8.0 1.7 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Sugar_tr PF00083.19 KPI42212.1 - 1.1e-81 274.7 34.8 1.2e-81 274.5 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI42212.1 - 7.3e-13 47.9 44.5 4.6e-12 45.3 7.1 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KPI42212.1 - 0.0062 16.5 10.7 0.36 10.8 1.1 3.2 2 1 0 2 2 2 2 Protein of unknown function (DUF1228) Smr PF01713.16 KPI42212.1 - 0.17 12.1 0.2 0.88 9.8 0.0 2.2 2 0 0 2 2 2 0 Smr domain FGGY_C PF02782.11 KPI42213.1 - 2.9e-48 164.1 0.4 4.6e-48 163.4 0.3 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KPI42213.1 - 1.6e-22 80.0 1.1 7.3e-20 71.3 0.1 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KPI42213.1 - 0.054 12.7 0.2 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family RPAP2_Rtr1 PF04181.8 KPI42214.1 - 2.9e-14 52.9 0.3 4.9e-14 52.1 0.2 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family ABC_membrane PF00664.18 KPI42215.1 - 1.8e-90 303.1 39.2 8.1e-46 156.6 12.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KPI42215.1 - 3.8e-66 221.5 0.0 2e-32 112.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KPI42215.1 - 9e-16 57.7 0.0 2e-05 23.9 0.0 3.6 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KPI42215.1 - 3.7e-10 40.2 0.1 0.41 10.5 0.0 4.4 3 1 1 4 4 4 4 AAA domain ABC_ATPase PF09818.4 KPI42215.1 - 6.2e-09 34.9 2.6 0.0024 16.5 0.1 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 KPI42215.1 - 3.4e-08 32.8 0.9 0.00066 19.1 0.1 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KPI42215.1 - 4e-07 30.2 3.2 0.0035 17.3 0.1 3.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.1 KPI42215.1 - 2.3e-06 27.1 0.2 0.02 14.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KPI42215.1 - 8.4e-06 26.6 0.0 0.22 12.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KPI42215.1 - 5.5e-05 22.4 0.2 0.18 10.9 0.0 2.8 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 KPI42215.1 - 0.00025 20.6 3.9 0.78 9.2 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 KPI42215.1 - 0.0003 20.9 3.2 3.7 7.7 0.1 4.6 4 1 0 4 4 4 2 AAA domain AAA_18 PF13238.1 KPI42215.1 - 0.0009 19.5 0.0 1.6 9.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KPI42215.1 - 0.0029 17.4 0.0 1.9 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KPI42215.1 - 0.0034 17.2 0.4 1.3 8.7 0.1 2.8 2 0 0 2 2 2 1 Domain of unknown function DUF87 SbcCD_C PF13558.1 KPI42215.1 - 0.0055 16.5 7.1 0.73 9.7 0.2 3.9 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 KPI42215.1 - 0.0075 16.2 0.1 1.6 8.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 KPI42215.1 - 0.0083 14.8 0.0 2.2 6.8 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_14 PF13173.1 KPI42215.1 - 0.013 15.4 0.0 6.4 6.6 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_10 PF12846.2 KPI42215.1 - 0.014 14.8 3.5 12 5.2 0.1 4.1 4 0 0 4 4 4 0 AAA-like domain AAA_5 PF07728.9 KPI42215.1 - 0.022 14.5 0.9 11 5.7 0.0 3.5 5 0 0 5 5 3 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KPI42215.1 - 0.023 14.4 0.8 1.5 8.5 0.2 3.1 2 0 0 2 2 2 0 Part of AAA domain AAA_23 PF13476.1 KPI42215.1 - 0.023 15.0 0.2 2.2 8.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain PRK PF00485.13 KPI42215.1 - 0.078 12.5 0.0 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family HET PF06985.6 KPI42216.1 - 5.8e-32 110.7 0.6 5.8e-32 110.7 0.4 2.8 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) Corona_nucleoca PF00937.13 KPI42216.1 - 0.0047 15.9 11.6 0.0074 15.2 8.0 1.2 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein DUF1777 PF08648.7 KPI42216.1 - 0.088 12.5 26.0 0.3 10.8 18.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF566 PF04484.7 KPI42216.1 - 8.1 5.8 15.0 0.26 10.7 6.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF566) SSF PF00474.12 KPI42217.1 - 3.4e-20 72.0 20.7 3.4e-20 72.0 14.4 1.7 2 0 0 2 2 2 1 Sodium:solute symporter family 7tm_7 PF08395.7 KPI42217.1 - 0.0035 16.4 0.5 0.0035 16.4 0.3 2.8 3 0 0 3 3 3 1 7tm Chemosensory receptor Peptidase_S41 PF03572.13 KPI42218.1 - 0.00074 18.9 0.0 0.0016 17.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family S41 LisH PF08513.6 KPI42219.1 - 2e-09 36.8 0.6 2.3e-05 23.9 0.0 3.1 3 0 0 3 3 3 2 LisH Zn_clus PF00172.13 KPI42219.1 - 0.00016 21.5 5.3 0.00026 20.8 3.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF434 PF04256.7 KPI42219.1 - 0.085 12.2 0.1 12 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF434) RCC1 PF00415.13 KPI42220.1 - 4.3e-48 161.3 18.0 2.2e-11 43.7 0.2 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KPI42220.1 - 2.6e-31 106.5 35.1 4.3e-08 32.5 1.3 6.6 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Mgm101p PF06420.7 KPI42221.1 - 8.6e-92 305.1 0.0 1.3e-91 304.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 CHCH PF06747.8 KPI42221.1 - 3.8e-06 26.6 6.8 1.1e-05 25.2 4.7 1.8 1 0 0 1 1 1 1 CHCH domain Phosphodiest PF01663.17 KPI42222.1 - 6.9e-17 61.8 1.5 2.5e-15 56.6 1.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KPI42222.1 - 0.0044 16.4 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KPI42222.1 - 0.056 12.6 0.9 0.14 11.3 0.0 2.1 3 0 0 3 3 3 0 Sulfatase CAP_N PF01213.14 KPI42223.1 - 0.055 12.7 2.5 0.12 11.6 1.7 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-CCCH PF00642.19 KPI42223.1 - 0.11 12.1 10.3 11 5.8 0.1 3.8 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3746 PF12562.3 KPI42223.1 - 0.14 12.0 1.9 3 7.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3746) zf-CCCH_2 PF14608.1 KPI42223.1 - 4.5 7.4 9.9 2.3 8.3 1.1 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Gly_transf_sug PF04488.10 KPI42224.1 - 8.1e-13 48.6 0.0 2.1e-12 47.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif zf-met2 PF12907.2 KPI42225.1 - 5.2e-14 51.9 0.2 7.1e-14 51.4 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 KPI42225.1 - 5.3e-08 33.4 9.4 8.2e-08 32.8 6.5 1.3 1 0 0 1 1 1 1 4F5 protein family zf-C2H2_6 PF13912.1 KPI42225.1 - 0.05 13.5 0.1 0.082 12.8 0.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger p450 PF00067.17 KPI42227.1 - 7.6e-56 189.5 0.0 1.1e-55 189.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 KPI42228.1 - 2.8e-48 164.4 1.2 3.8e-48 163.9 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.8 KPI42228.1 - 4.6e-46 157.0 0.0 1e-45 155.9 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KPI42228.1 - 7.9e-05 21.5 0.5 0.00021 20.1 0.3 1.5 1 1 0 1 1 1 1 Carboxylesterase family DUF4404 PF14357.1 KPI42228.1 - 0.081 13.3 0.4 0.58 10.6 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) HpcH_HpaI PF03328.9 KPI42229.1 - 9.2e-27 93.3 0.0 1.1e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family p450 PF00067.17 KPI42230.1 - 8.2e-67 225.7 0.0 9.5e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 KPI42231.1 - 7.9e-21 74.4 0.1 9.4e-15 54.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KPI42231.1 - 9.3e-08 31.9 0.5 2.8e-07 30.4 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI42231.1 - 1.7e-06 27.2 4.8 2.2e-06 26.8 1.1 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI42231.1 - 3.2e-06 27.1 0.2 6.4e-06 26.1 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI42231.1 - 4.4e-06 25.8 0.8 6.5e-06 25.2 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KPI42231.1 - 1.3e-05 24.3 0.0 2.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 KPI42231.1 - 6.4e-05 23.2 0.0 0.00045 20.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KPI42231.1 - 0.00041 19.5 0.1 0.00062 18.9 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KPI42231.1 - 0.00069 18.5 0.1 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KPI42231.1 - 0.00081 19.5 0.0 0.0018 18.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KPI42231.1 - 0.0012 18.0 0.2 0.11 11.4 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 KPI42231.1 - 0.0099 14.3 0.8 0.018 13.5 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 KPI42231.1 - 0.014 15.0 0.1 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 KPI42231.1 - 0.023 13.7 0.1 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 KPI42231.1 - 0.028 13.0 0.2 0.57 8.7 0.1 2.6 2 1 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KPI42231.1 - 0.033 13.9 0.6 0.1 12.3 0.2 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KPI42231.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KPI42231.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.19 KPI42232.1 - 1.4e-76 257.9 27.2 1.6e-76 257.7 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI42232.1 - 3.1e-26 91.9 40.5 1.5e-24 86.3 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_43 PF04616.9 KPI42233.1 - 3e-26 92.1 0.0 3.8e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Orthopox_A36R PF05950.6 KPI42233.1 - 0.17 11.8 0.1 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A36R protein Amidohydro_5 PF13594.1 KPI42234.1 - 4.8e-08 32.6 0.0 1.6e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KPI42234.1 - 2e-06 27.6 4.4 7.7e-06 25.7 3.1 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KPI42234.1 - 0.00063 19.0 0.7 1.1 8.4 0.2 3.1 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KPI42234.1 - 0.015 15.3 5.2 0.36 10.8 3.6 2.7 1 1 0 1 1 1 0 Amidohydrolase WD40 PF00400.27 KPI42235.1 - 1.1e-35 120.2 4.6 6.4e-07 29.0 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KPI42235.1 - 2.5e-08 33.8 0.1 0.0086 15.8 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Beta-Casp PF10996.3 KPI42236.1 - 2.9e-23 82.1 0.0 2e-22 79.4 0.0 2.4 2 0 0 2 2 2 1 Beta-Casp domain CPSF100_C PF13299.1 KPI42236.1 - 9.2e-07 29.1 0.4 9.2e-07 29.1 0.2 2.7 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.7 KPI42236.1 - 0.00052 19.7 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 KPI42236.1 - 0.055 13.1 0.2 0.26 10.9 0.1 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily adh_short PF00106.20 KPI42237.1 - 2e-30 105.9 3.0 3.4e-30 105.1 2.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI42237.1 - 9.4e-25 87.7 0.1 1.1e-24 87.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI42237.1 - 1.3e-13 51.0 1.7 4.7e-13 49.2 1.1 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KPI42237.1 - 8.5e-07 28.1 0.1 5.5e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KPI42237.1 - 4.4e-06 26.2 0.1 6.5e-06 25.7 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 KPI42237.1 - 0.0081 15.9 0.2 0.016 15.0 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 KPI42237.1 - 0.012 15.4 3.7 0.028 14.2 2.6 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HHH_5 PF14520.1 KPI42237.1 - 0.019 15.1 0.2 0.054 13.6 0.1 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix domain ThiF PF00899.16 KPI42237.1 - 0.41 10.4 2.0 3.3 7.5 1.2 2.1 1 1 0 1 1 1 0 ThiF family FA_hydroxylase PF04116.8 KPI42238.1 - 1.9e-13 50.7 21.6 4.1e-13 49.7 12.6 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SnoaL_2 PF12680.2 KPI42239.1 - 0.088 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain F-box-like PF12937.2 KPI42240.1 - 1.3e-10 40.8 0.9 2.6e-10 39.8 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KPI42240.1 - 2.3e-09 36.6 0.5 4.5e-09 35.7 0.3 1.5 1 0 0 1 1 1 1 F-box domain TPP_enzyme_N PF02776.13 KPI42241.1 - 2.1e-27 95.6 0.1 3.7e-27 94.8 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KPI42241.1 - 3.3e-18 65.7 0.0 6.9e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KPI42241.1 - 5.8e-18 64.9 0.0 1.3e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain UCH PF00443.24 KPI42242.1 - 4.3e-48 163.7 0.0 5.6e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KPI42242.1 - 5.6e-11 42.4 0.8 1e-09 38.2 0.5 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KPI42242.1 - 0.031 13.6 0.0 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Anoctamin PF04547.7 KPI42243.1 - 3.2e-99 332.6 3.2 4.8e-99 332.0 2.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Sugar_tr PF00083.19 KPI42244.1 - 2.5e-68 230.7 20.3 7.5e-59 199.4 10.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI42244.1 - 5e-14 51.7 29.7 5.1e-12 45.1 12.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 KPI42245.1 - 6.3e-28 97.6 1.2 1.1e-27 96.8 0.8 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Raffinose_syn PF05691.7 KPI42247.1 - 1.2e-54 185.1 0.7 9.3e-48 162.3 0.5 3.5 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 KPI42247.1 - 0.00031 19.5 0.0 0.00058 18.6 0.0 1.4 1 0 0 1 1 1 1 Melibiase Aldo_ket_red PF00248.16 KPI42248.1 - 1.3e-48 165.3 0.0 1.5e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family P3A PF08727.6 KPI42248.1 - 0.0047 16.2 0.3 3.4 7.0 0.1 2.4 2 0 0 2 2 2 2 Poliovirus 3A protein like MFS_1 PF07690.11 KPI42249.1 - 8.6e-36 123.3 28.3 7.2e-34 117.0 21.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4064 PF13273.1 KPI42249.1 - 0.0055 16.7 6.8 0.54 10.3 0.3 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF4064) CNH PF00780.17 KPI42250.1 - 1.3e-67 228.1 0.0 1.9e-67 227.5 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 KPI42250.1 - 3.9e-23 82.2 0.3 9.7e-22 77.6 0.2 2.3 1 1 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 KPI42250.1 - 7.8e-06 25.8 0.0 3.1e-05 23.9 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain Porin_3 PF01459.17 KPI42252.1 - 1.2e-73 247.8 0.0 1.4e-73 247.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin ADH_N PF08240.7 KPI42253.1 - 3.9e-06 26.6 0.7 3.8e-05 23.4 0.5 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Metallophos_2 PF12850.2 KPI42254.1 - 0.045 13.5 0.1 0.29 10.9 0.1 2.1 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.17 KPI42255.1 - 6.2e-18 64.2 0.0 2.5e-13 49.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI42255.1 - 2e-10 40.4 0.0 1.3e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MBOAT_2 PF13813.1 KPI42256.1 - 2.7e-13 49.8 1.0 6.9e-13 48.4 0.2 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family zf-C2H2 PF00096.21 KPI42257.1 - 1.5e-12 47.0 15.4 4.4e-05 23.5 1.8 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI42257.1 - 3.8e-09 36.2 12.0 0.00076 19.6 1.3 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KPI42257.1 - 7.5e-08 32.3 23.7 3.4e-07 30.2 0.9 4.7 4 1 0 4 4 4 3 Zinc-finger double domain zf-met PF12874.2 KPI42257.1 - 0.0031 17.6 1.8 0.12 12.6 0.1 3.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KPI42257.1 - 0.94 9.4 4.3 1.5 8.8 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Acyl-CoA_dh_1 PF00441.19 KPI42258.1 - 3e-19 69.5 1.2 9.4e-19 67.9 0.4 2.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KPI42258.1 - 1.7e-12 46.6 0.0 3.3e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KPI42258.1 - 1.8e-12 47.8 0.0 4.2e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KPI42258.1 - 1e-10 41.9 0.2 1.8e-10 41.1 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Abhydro_lipase PF04083.11 KPI42259.1 - 2.1e-21 75.0 0.0 3.9e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KPI42259.1 - 5.4e-17 62.1 0.3 1.1e-16 61.1 0.2 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI42259.1 - 1.6e-06 28.2 0.0 3.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KPI42259.1 - 0.00097 18.6 0.0 0.37 10.2 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) IL12 PF03039.9 KPI42259.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Interleukin-12 alpha subunit NAD_binding_11 PF14833.1 KPI42260.1 - 4e-32 110.8 0.0 6.1e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 KPI42260.1 - 5.4e-32 110.8 0.1 7.6e-32 110.4 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KPI42260.1 - 0.00044 19.4 0.0 0.00075 18.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KPI42260.1 - 0.0044 17.4 0.1 0.0093 16.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent SUFU PF05076.8 KPI42260.1 - 0.088 12.3 0.0 0.3 10.6 0.0 1.9 1 1 1 2 2 2 0 Suppressor of fused protein (SUFU) DUF973 PF06157.6 KPI42261.1 - 0.49 9.3 11.0 0.062 12.2 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF973) FTR1 PF03239.9 KPI42262.1 - 1.8e-82 276.7 8.0 3.2e-82 275.9 5.5 1.3 1 1 0 1 1 1 1 Iron permease FTR1 family DUF4231 PF14015.1 KPI42262.1 - 0.0088 16.0 0.4 0.0088 16.0 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4231) DUF4293 PF14126.1 KPI42262.1 - 0.71 9.7 4.1 6.9 6.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF2721 PF11026.3 KPI42262.1 - 1 9.0 11.4 0.41 10.2 0.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2721) DUF4396 PF14342.1 KPI42262.1 - 3.8 7.6 8.1 0.094 12.8 0.5 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4396) NAD_kinase PF01513.16 KPI42263.1 - 1.8e-48 164.7 0.0 2.5e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase His_Phos_2 PF00328.17 KPI42264.1 - 6.4e-13 48.7 0.1 5.6e-11 42.3 0.1 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4267 PF14087.1 KPI42265.1 - 5.7e-13 48.4 1.7 7e-13 48.1 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) SLH PF00395.15 KPI42265.1 - 0.14 11.9 0.0 0.93 9.2 0.0 2.1 2 0 0 2 2 2 0 S-layer homology domain Shisa PF13908.1 KPI42266.1 - 0.017 15.3 0.2 1.5 8.9 0.5 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator VSP PF03302.8 KPI42266.1 - 0.06 11.9 3.5 0.086 11.4 2.4 1.4 1 1 0 1 1 1 0 Giardia variant-specific surface protein Podoplanin PF05808.6 KPI42266.1 - 7.2 6.1 13.5 32 4.0 9.4 2.0 1 1 0 1 1 1 0 Podoplanin Clr5 PF14420.1 KPI42267.1 - 2.8e-11 43.1 0.1 8.5e-11 41.5 0.1 1.8 2 0 0 2 2 1 1 Clr5 domain TPR_10 PF13374.1 KPI42267.1 - 1.1e-05 25.1 0.6 0.15 12.0 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KPI42267.1 - 0.00011 22.0 0.3 0.0013 18.6 0.4 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KPI42267.1 - 0.00017 21.9 4.9 0.19 12.4 0.4 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 KPI42267.1 - 0.00062 19.9 11.6 0.0029 17.8 0.8 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KPI42267.1 - 0.0011 19.2 1.3 0.038 14.3 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KPI42267.1 - 0.014 15.5 0.2 0.23 11.7 0.1 3.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KPI42267.1 - 0.023 15.3 11.1 0.05 14.2 0.9 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 KPI42267.1 - 0.028 14.5 0.2 0.32 11.1 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KPI42267.1 - 0.038 14.4 1.0 0.19 12.2 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KPI42267.1 - 0.1 12.4 0.9 9.7 6.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KPI42267.1 - 0.15 11.6 0.2 0.57 9.8 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 KPI42267.1 - 0.18 11.9 2.9 0.13 12.4 0.2 2.2 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Acyltransferase PF01553.16 KPI42268.1 - 3.2e-22 78.3 0.0 5e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase AA_permease PF00324.16 KPI42269.1 - 1.5e-139 465.4 39.7 1.7e-139 465.2 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI42269.1 - 1.9e-42 145.3 40.6 2.5e-42 144.9 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease LTV PF04180.9 KPI42270.1 - 8.6e-66 223.1 13.1 1.4e-65 222.5 9.1 1.3 1 0 0 1 1 1 1 Low temperature viability protein S-AdoMet_synt_M PF02772.11 KPI42271.1 - 0.088 12.7 1.0 0.13 12.1 0.7 1.3 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, central domain MFS_1 PF07690.11 KPI42272.1 - 1.4e-20 73.3 55.7 2.5e-17 62.6 30.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C3H1 PF10650.4 KPI42273.1 - 6.2e-07 28.7 1.7 1.1e-06 28.0 1.2 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain Cluap1 PF10234.4 KPI42273.1 - 0.093 11.9 11.4 0.17 11.0 7.9 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 V_ATPase_I PF01496.14 KPI42273.1 - 0.93 7.2 9.5 1.4 6.7 6.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 KPI42273.1 - 2.2 6.8 14.8 3.6 6.1 10.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 KPI42273.1 - 2.4 7.6 22.4 4.8 6.7 15.5 1.4 1 0 0 1 1 1 0 IncA protein COG2 PF06148.6 KPI42273.1 - 6.7 6.5 9.6 3.5 7.5 3.9 2.3 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FSH1 PF03959.8 KPI42274.1 - 5.5e-39 133.8 0.0 7.5e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Grp1_Fun34_YaaH PF01184.14 KPI42275.1 - 6.1e-60 202.1 13.7 7.1e-60 201.8 9.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ECH PF00378.15 KPI42276.1 - 3e-28 98.6 0.0 3.4e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Methyltransf_31 PF13847.1 KPI42277.1 - 9.9e-14 51.1 0.0 1.5e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI42277.1 - 9.9e-13 48.1 0.0 1.8e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI42277.1 - 9.6e-12 45.4 0.0 1.6e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI42277.1 - 6.2e-11 42.5 0.1 1.3e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI42277.1 - 7.9e-11 42.3 0.1 2.3e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI42277.1 - 1.7e-09 38.0 0.0 3.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI42277.1 - 1.6e-08 33.9 0.0 4.5e-07 29.2 0.0 2.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KPI42277.1 - 2.4e-05 24.3 0.2 9.6e-05 22.3 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 KPI42277.1 - 0.00048 19.6 0.0 0.0013 18.2 0.0 1.7 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.9 KPI42277.1 - 0.001 18.4 0.0 0.0056 16.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 KPI42277.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 KPI42277.1 - 0.023 13.8 0.0 0.062 12.4 0.0 1.6 1 1 0 1 1 1 0 Tellurite resistance protein TehB DUF1772 PF08592.6 KPI42278.1 - 2.8e-15 56.2 0.3 2.3e-10 40.3 0.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) TB2_DP1_HVA22 PF03134.14 KPI42279.1 - 2.2e-25 88.1 3.4 3.2e-25 87.7 2.4 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family WSC PF01822.14 KPI42280.1 - 1.7e-29 101.5 31.8 1.5e-16 60.1 7.9 2.6 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.18 KPI42280.1 - 3.6e-18 65.8 0.0 9e-18 64.6 0.0 1.6 1 1 0 1 1 1 1 Peroxidase MAPEG PF01124.13 KPI42281.1 - 4.1e-13 49.0 0.8 7.5e-13 48.2 0.6 1.4 1 0 0 1 1 1 1 MAPEG family DUF2296 PF10058.4 KPI42282.1 - 1.3e-20 72.8 0.1 2.3e-20 72.0 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) SMI1_KNR4 PF09346.5 KPI42283.1 - 1.1e-28 99.7 0.0 2.2e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) PPP4R2 PF09184.6 KPI42283.1 - 0.78 9.2 6.3 0.32 10.4 2.4 1.8 2 0 0 2 2 2 0 PPP4R2 AA_permease_2 PF13520.1 KPI42284.1 - 1.5e-17 63.3 22.8 2e-17 62.8 15.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI42284.1 - 5.4e-12 44.7 18.1 6.8e-12 44.4 12.5 1.1 1 0 0 1 1 1 1 Amino acid permease Ldh_2 PF02615.9 KPI42285.1 - 3e-56 190.5 0.0 4.7e-56 189.9 0.0 1.3 1 1 0 1 1 1 1 Malate/L-lactate dehydrogenase zf-C3HC4_3 PF13920.1 KPI42286.1 - 6.7e-09 35.2 4.2 1.2e-08 34.5 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 KPI42286.1 - 3.6e-08 32.9 2.3 6.4e-08 32.0 1.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 KPI42286.1 - 3.6e-08 33.2 9.6 6.1e-08 32.5 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI42286.1 - 1.4e-06 27.8 8.9 2.4e-06 27.0 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI42286.1 - 3.1e-06 26.8 8.0 5.3e-06 26.0 5.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KPI42286.1 - 4e-06 26.5 6.2 6.7e-06 25.8 4.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KPI42286.1 - 0.0001 21.9 1.4 0.00023 20.8 1.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KPI42286.1 - 0.0048 16.7 7.6 0.011 15.6 5.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 KPI42286.1 - 0.29 10.7 4.0 0.6 9.7 2.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 KPI42286.1 - 1.2 9.3 4.3 2.8 8.1 3.0 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger GTP_CH_N PF12471.3 KPI42287.1 - 5.4e-91 303.5 0.0 7.7e-91 303.0 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 KPI42287.1 - 1.6e-16 59.9 0.0 2.9e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II HCR PF07111.7 KPI42287.1 - 0.15 10.0 0.0 0.2 9.6 0.0 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) adh_short PF00106.20 KPI42288.1 - 4.9e-23 81.8 0.0 7.6e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI42288.1 - 6e-07 29.2 0.0 2.5e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI42288.1 - 3.2e-05 23.8 0.0 4.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI42289.1 - 3.6e-35 121.3 6.8 4.7e-35 120.9 4.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI42289.1 - 2.1e-25 89.8 1.8 3.3e-20 72.8 1.2 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI42289.1 - 2.1e-18 66.6 4.7 2.8e-18 66.2 3.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI42289.1 - 5.5e-06 25.9 1.3 1.2e-05 24.8 0.9 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI42289.1 - 0.0024 17.9 0.5 0.0063 16.5 0.3 1.7 1 1 0 1 1 1 1 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 KPI42289.1 - 0.0051 16.2 0.1 0.012 15.0 0.1 1.7 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Met_10 PF02475.11 KPI42289.1 - 0.028 13.9 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DUF4406 PF14359.1 KPI42289.1 - 0.029 14.4 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) 3HCDH_N PF02737.13 KPI42289.1 - 0.053 13.1 0.8 0.12 12.0 0.5 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CW_binding_2 PF04122.7 KPI42289.1 - 0.1 12.8 1.2 0.27 11.4 0.1 2.0 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 Vfa1 PF08432.5 KPI42290.1 - 4.1e-52 176.8 19.2 5.4e-40 137.3 9.6 2.1 2 0 0 2 2 2 2 AAA-ATPase Vps4-associated protein 1 Ycf1 PF05758.7 KPI42290.1 - 0.018 12.7 1.2 0.02 12.6 0.9 1.1 1 0 0 1 1 1 0 Ycf1 PAPA-1 PF04795.7 KPI42290.1 - 0.02 15.5 8.0 0.044 14.4 5.6 1.6 1 0 0 1 1 1 0 PAPA-1-like conserved region DUF1510 PF07423.6 KPI42290.1 - 0.44 9.8 12.4 0.67 9.2 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNA_polI_A34 PF08208.6 KPI42290.1 - 2.2 7.9 19.1 3.8 7.1 13.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.9 KPI42290.1 - 3.8 5.4 8.2 5.3 4.9 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein ATP-synt_E PF05680.7 KPI42290.1 - 7.5 6.5 13.3 4.8 7.1 7.5 2.0 2 0 0 2 2 2 0 ATP synthase E chain Fungal_trans_2 PF11951.3 KPI42293.1 - 2.6e-44 151.3 0.1 3.8e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI42293.1 - 2.1e-07 30.7 13.8 3.5e-07 29.9 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adap_comp_sub PF00928.16 KPI42294.1 - 4.2e-85 285.0 0.0 5.3e-85 284.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KPI42294.1 - 5e-05 23.0 0.1 8.6e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Fungal_trans PF04082.13 KPI42295.1 - 7.5e-15 54.5 0.5 1.2e-14 53.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI42295.1 - 5.5e-07 29.3 10.2 9.9e-07 28.5 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.13 KPI42297.1 - 2.3e-94 316.1 18.0 2.3e-94 316.1 12.5 1.4 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KPI42297.1 - 5.8e-05 22.0 20.2 5.8e-05 22.0 14.0 2.0 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family SH3_1 PF00018.23 KPI42298.1 - 2.1e-09 36.6 0.4 5.3e-09 35.3 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KPI42298.1 - 8.4e-07 28.4 0.0 1.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KPI42298.1 - 3e-06 26.6 0.0 5.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain EcsB PF05975.7 KPI42298.1 - 0.1 11.0 5.0 0.14 10.6 3.4 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB YhhN PF07947.9 KPI42298.1 - 0.14 11.4 9.2 0.2 10.9 6.4 1.2 1 0 0 1 1 1 0 YhhN-like protein Herpes_LMP1 PF05297.6 KPI42298.1 - 1.6 7.5 3.7 14 4.4 0.8 2.1 1 1 1 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1129 PF06570.6 KPI42298.1 - 2.6 7.2 10.8 0.84 8.9 5.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) FixP_N PF14715.1 KPI42298.1 - 6.6 6.1 8.0 4.6 6.7 0.9 2.8 2 1 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Ras PF00071.17 KPI42299.1 - 2.3e-49 166.8 0.0 2.8e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KPI42299.1 - 2.7e-15 56.9 0.0 5.3e-15 55.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KPI42299.1 - 2.5e-10 39.8 0.0 3.4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 KPI42299.1 - 0.00039 20.5 0.1 0.0021 18.2 0.0 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 KPI42299.1 - 0.0013 17.9 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 KPI42299.1 - 0.03 13.6 0.1 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 KPI42299.1 - 0.044 12.4 2.1 0.78 8.3 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 KPI42299.1 - 0.052 13.7 0.2 0.16 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KPI42299.1 - 0.084 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain GFA PF04828.9 KPI42300.1 - 0.00011 22.0 0.0 0.00025 20.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Pex14_N PF04695.8 KPI42301.1 - 0.0049 16.9 0.0 0.008 16.2 0.0 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Homez PF11569.3 KPI42301.1 - 0.14 11.2 0.2 0.71 8.9 0.3 1.9 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Cu-oxidase_2 PF07731.9 KPI42302.1 - 4.9e-19 68.2 0.3 2.6e-18 65.8 0.2 2.1 1 1 0 1 1 1 1 Multicopper oxidase zf-RanBP PF00641.13 KPI42302.1 - 0.00012 21.0 0.4 0.00012 21.0 0.3 2.0 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Fungal_trans PF04082.13 KPI42303.1 - 0.024 13.5 0.3 0.12 11.1 0.1 2.0 2 0 0 2 2 2 0 Fungal specific transcription factor domain Allexi_40kDa PF05549.6 KPI42304.1 - 0.031 13.5 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein UME PF08064.8 KPI42304.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 UME (NUC010) domain HasA PF06438.7 KPI42304.1 - 0.1 11.9 1.1 0.18 11.1 0.3 1.6 1 1 0 1 1 1 0 Heme-binding protein A (HasA) DUF3440 PF11922.3 KPI42304.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) ADH_zinc_N PF00107.21 KPI42305.1 - 2.5e-16 59.4 0.1 4.7e-16 58.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI42305.1 - 0.00021 21.0 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KPI42305.1 - 0.04 14.8 0.1 0.093 13.6 0.1 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ABC_membrane PF00664.18 KPI42307.1 - 3.4e-68 230.0 29.7 1.4e-40 139.5 5.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KPI42307.1 - 2.6e-65 218.8 0.0 1.9e-33 115.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KPI42307.1 - 6.6e-16 58.1 0.0 2.3e-05 23.7 0.1 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KPI42307.1 - 2.2e-10 39.9 0.2 0.00085 18.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KPI42307.1 - 7e-10 39.7 0.0 0.00061 20.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KPI42307.1 - 1.3e-08 35.2 0.0 0.1 12.5 0.0 4.3 3 1 0 4 4 4 1 AAA domain AAA_22 PF13401.1 KPI42307.1 - 3.2e-08 33.8 0.8 0.085 12.9 0.0 4.3 3 1 1 4 4 4 2 AAA domain AAA_16 PF13191.1 KPI42307.1 - 1.1e-07 32.0 7.6 0.00031 20.8 0.3 3.2 3 1 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KPI42307.1 - 5.8e-06 25.5 0.0 0.0066 15.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 KPI42307.1 - 2.4e-05 23.9 0.1 0.19 11.2 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 KPI42307.1 - 3.7e-05 23.6 0.0 0.21 11.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KPI42307.1 - 4.9e-05 23.6 0.0 0.28 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.15 KPI42307.1 - 0.0001 22.0 0.1 0.056 13.0 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 KPI42307.1 - 0.00014 21.0 0.0 0.053 12.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 KPI42307.1 - 0.00022 21.6 0.2 0.44 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KPI42307.1 - 0.00025 19.7 0.1 0.09 11.3 0.0 3.1 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_25 PF13481.1 KPI42307.1 - 0.00028 20.3 1.0 0.53 9.6 0.0 3.1 4 0 0 4 4 3 2 AAA domain SbcCD_C PF13558.1 KPI42307.1 - 0.0007 19.4 0.2 0.41 10.5 0.1 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 KPI42307.1 - 0.00098 18.8 2.4 1.4 8.7 0.1 3.6 3 0 0 3 3 2 2 Part of AAA domain AAA_10 PF12846.2 KPI42307.1 - 0.0021 17.5 0.4 2.9 7.2 0.0 3.0 3 0 0 3 3 3 2 AAA-like domain DUF87 PF01935.12 KPI42307.1 - 0.0029 17.4 0.1 0.89 9.3 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_5 PF07728.9 KPI42307.1 - 0.0035 17.0 0.1 4.3 7.0 0.0 3.3 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) SRP54 PF00448.17 KPI42307.1 - 0.0035 16.8 1.1 1.6 8.1 0.0 3.6 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 KPI42307.1 - 0.0051 16.7 0.0 2.1 8.3 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.1 KPI42307.1 - 0.017 15.0 0.0 3.4 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KPI42307.1 - 0.026 14.2 0.0 5.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 KPI42307.1 - 0.046 13.2 0.1 9 5.7 0.0 3.1 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF3987 PF13148.1 KPI42307.1 - 0.046 12.2 0.0 4.4 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_28 PF13521.1 KPI42307.1 - 0.11 12.5 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zn_clus PF00172.13 KPI42308.1 - 3.3e-05 23.6 13.7 5.8e-05 22.9 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KPI42308.1 - 0.00081 18.3 0.1 0.0015 17.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nsp1_C PF05064.8 KPI42308.1 - 0.039 13.5 0.6 0.091 12.4 0.3 1.7 1 1 0 1 1 1 0 Nsp1-like C-terminal region Dickkopf_N PF04706.7 KPI42308.1 - 0.06 13.5 11.2 0.13 12.4 7.8 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region DUF605 PF04652.11 KPI42308.1 - 2.1 7.6 16.4 4.3 6.6 11.4 1.5 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KPI42308.1 - 7.9 4.5 18.5 13 3.8 12.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MMR_HSR1 PF01926.18 KPI42310.1 - 2e-17 63.2 0.3 1.7e-15 56.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KPI42310.1 - 9.8e-08 31.4 0.4 1.1e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 KPI42310.1 - 6e-05 22.2 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KPI42310.1 - 0.011 14.8 0.1 0.011 14.8 0.1 2.1 2 1 0 2 2 2 0 AIG1 family Miro PF08477.8 KPI42310.1 - 0.034 14.6 0.8 0.093 13.2 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 KPI42310.1 - 0.035 13.9 5.1 0.06 13.1 0.0 3.2 3 0 0 3 3 3 0 Dynamin family ArgK PF03308.11 KPI42310.1 - 0.04 12.6 0.9 0.39 9.4 0.0 2.3 2 0 0 2 2 2 0 ArgK protein cobW PF02492.14 KPI42310.1 - 0.066 12.6 1.4 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Glyco_transf_17 PF04724.8 KPI42312.1 - 4.2e-19 68.7 0.0 5.9e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 SnoaL_4 PF13577.1 KPI42313.1 - 3.4e-20 72.2 0.2 4.5e-20 71.8 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 KPI42313.1 - 0.0015 18.9 0.4 0.003 17.9 0.2 1.6 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KPI42313.1 - 0.0021 18.2 0.4 0.0043 17.2 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) Cu_amine_oxid PF01179.15 KPI42315.1 - 7e-142 472.9 0.0 2.5e-139 464.5 0.0 2.1 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KPI42315.1 - 5.8e-12 45.5 0.0 1.3e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KPI42315.1 - 2.7e-08 33.7 0.0 6.6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain DUF1014 PF06244.7 KPI42316.1 - 9.7 6.4 6.2 6.7 6.9 2.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1014) Glyco_hydro_63 PF03200.11 KPI42317.1 - 3e-233 776.1 0.0 2.7e-232 773.0 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 KPI42317.1 - 0.0024 16.6 0.4 0.0024 16.6 0.3 1.7 2 0 0 2 2 2 1 Trehalase GDE_C PF06202.9 KPI42317.1 - 0.07 11.8 0.1 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase RTC PF01137.16 KPI42318.1 - 8.9e-29 99.8 0.0 1.3e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KPI42318.1 - 5.9e-25 87.2 0.0 1.2e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pkinase PF00069.20 KPI42319.1 - 7.6e-56 189.1 0.0 1.1e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI42319.1 - 8.1e-30 103.7 0.0 1.1e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI42319.1 - 1.6e-10 40.4 0.0 4.7e-09 35.6 0.0 2.7 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 KPI42319.1 - 0.04 12.9 0.0 0.078 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mg_trans_NIPA PF05653.9 KPI42320.1 - 1.5e-16 60.2 7.9 1.5e-08 33.9 0.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 KPI42320.1 - 3.2e-05 23.9 0.0 3.2e-05 23.9 0.0 2.8 3 0 0 3 3 3 1 EamA-like transporter family Multi_Drug_Res PF00893.14 KPI42320.1 - 0.31 11.5 7.6 0.4 11.1 0.2 2.9 3 0 0 3 3 3 0 Small Multidrug Resistance protein Neurensin PF14927.1 KPI42320.1 - 0.81 9.0 7.8 21 4.5 2.3 3.9 3 1 0 3 3 3 0 Neurensin DUF1077 PF06417.7 KPI42320.1 - 4.6 6.5 5.0 13 5.0 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1077) HAD_2 PF13419.1 KPI42321.1 - 1.7e-27 96.7 0.0 2.5e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase SIS_2 PF13580.1 KPI42321.1 - 0.038 13.6 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 SIS domain SH3_1 PF00018.23 KPI42322.1 - 2.3e-10 39.6 0.1 4.4e-10 38.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KPI42322.1 - 7.7e-09 34.9 0.1 1.5e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KPI42322.1 - 4.2e-08 32.5 0.0 8.3e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TPR_1 PF00515.23 KPI42323.1 - 5.5e-28 95.3 8.6 2.3e-06 26.9 0.0 10.3 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 KPI42323.1 - 6.4e-26 89.7 32.3 0.00019 21.0 0.4 11.3 9 2 2 11 11 11 8 TPR repeat TPR_2 PF07719.12 KPI42323.1 - 5.7e-22 75.8 23.0 0.0019 17.9 0.0 13.3 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_19 PF14559.1 KPI42323.1 - 3e-18 65.8 14.6 0.0004 20.6 0.0 10.5 8 4 2 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 KPI42323.1 - 4e-18 65.1 42.2 1.9e-06 27.7 1.3 12.4 13 1 1 14 14 12 5 Tetratricopeptide repeat TPR_8 PF13181.1 KPI42323.1 - 1.1e-15 56.1 20.5 0.00011 21.7 0.0 11.8 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_16 PF13432.1 KPI42323.1 - 1.9e-15 57.0 27.6 9e-07 29.4 0.0 11.4 9 2 4 13 13 13 3 Tetratricopeptide repeat TPR_14 PF13428.1 KPI42323.1 - 1.2e-13 50.3 21.1 0.074 13.7 0.0 12.3 12 1 1 13 13 12 2 Tetratricopeptide repeat TPR_17 PF13431.1 KPI42323.1 - 2.2e-07 30.5 10.1 6.7 7.1 0.0 9.8 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_6 PF13174.1 KPI42323.1 - 4.3e-07 29.9 33.1 0.034 14.6 0.0 11.6 14 0 0 14 14 11 2 Tetratricopeptide repeat Apc3 PF12895.2 KPI42323.1 - 3e-06 27.2 14.8 0.035 14.2 0.0 6.8 7 1 0 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 KPI42323.1 - 0.0073 16.0 3.7 0.17 11.7 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KPI42323.1 - 0.028 14.1 0.0 0.028 14.1 0.0 9.6 13 0 0 13 13 12 0 Tetratricopeptide repeat TPR_10 PF13374.1 KPI42323.1 - 1.7 8.6 25.0 2.1 8.4 0.0 8.0 8 1 1 9 9 9 0 Tetratricopeptide repeat EF1_GNE PF00736.14 KPI42324.1 - 2.2e-30 104.1 4.6 4.4e-30 103.2 3.2 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KPI42324.1 - 4.7e-12 45.8 3.3 4.7e-12 45.8 2.3 3.1 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.20 KPI42324.1 - 0.0022 17.9 0.3 0.0059 16.5 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KPI42324.1 - 0.056 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4604 PF15377.1 KPI42324.1 - 0.063 13.4 6.2 0.082 13.1 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Mcp5_PH PF12814.2 KPI42325.1 - 2.5e-43 146.9 0.1 4.6e-43 146.0 0.1 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology SGL PF08450.7 KPI42327.1 - 0.0017 17.8 0.1 0.92 8.8 0.0 2.3 1 1 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Pkip-1 PF06878.6 KPI42328.1 - 0.21 11.4 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 Pkip-1 protein vATP-synt_E PF01991.13 KPI42329.1 - 9.3e-58 194.7 9.5 1.1e-57 194.5 6.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF3435 PF11917.3 KPI42329.1 - 0.012 14.3 2.9 0.02 13.5 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) RHH_3 PF12651.2 KPI42329.1 - 5.2 6.8 7.6 3.5 7.4 0.1 3.7 3 1 1 4 4 4 0 Ribbon-helix-helix domain Myb_DNA-bind_6 PF13921.1 KPI42330.1 - 0.00031 20.7 0.1 0.00049 20.1 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_28 PF13518.1 KPI42330.1 - 0.081 12.9 0.2 0.16 11.9 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain IGF2_C PF08365.6 KPI42332.1 - 0.09 12.5 3.3 0.18 11.5 2.3 1.5 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide DUF3589 PF12141.3 KPI42333.1 - 3.1e-86 289.6 0.0 6.4e-86 288.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) DUF3425 PF11905.3 KPI42333.1 - 1.5e-13 50.8 0.1 2.9e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) RRM_1 PF00076.17 KPI42334.1 - 1.8e-18 65.9 0.0 2.6e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI42334.1 - 2.6e-14 52.9 0.0 4.2e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI42334.1 - 6.1e-09 35.5 0.0 9.5e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KPI42334.1 - 1.4e-07 31.8 7.9 1.4e-07 31.8 5.5 4.7 3 1 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 Thaumatin PF00314.12 KPI42335.1 - 0.023 14.1 1.4 1.7 8.0 0.2 2.5 1 1 1 2 2 2 0 Thaumatin family Lipoprotein_15 PF03640.10 KPI42335.1 - 0.15 11.5 1.5 1.1 8.8 0.4 2.3 2 0 0 2 2 2 0 Secreted repeat of unknown function Pyr_redox PF00070.22 KPI42336.1 - 8.7e-12 45.2 0.3 8.7e-10 38.8 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI42336.1 - 9.4e-08 32.1 1.0 1e-05 25.4 0.7 3.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI42336.1 - 7.1e-07 29.4 0.0 0.00028 21.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI42336.1 - 0.00087 18.2 0.3 0.0055 15.6 0.2 1.9 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 KPI42336.1 - 0.0036 15.9 0.2 1.4 7.4 0.2 2.6 3 0 0 3 3 3 2 Tryptophan halogenase DAO PF01266.19 KPI42336.1 - 0.0077 15.1 2.5 0.0099 14.8 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KPI42336.1 - 0.015 14.3 1.0 14 4.5 0.1 3.1 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.7 KPI42336.1 - 0.019 13.8 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KPI42336.1 - 0.036 12.9 0.3 0.64 8.8 0.1 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A SNF2_N PF00176.18 KPI42337.1 - 2.8e-71 239.7 3.3 6.2e-71 238.6 2.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 KPI42337.1 - 2.5e-51 173.4 24.8 2.5e-51 173.4 17.2 4.7 5 1 0 5 5 5 1 DNA-binding domain Helicase_C PF00271.26 KPI42337.1 - 2.2e-16 59.4 0.0 5.7e-16 58.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DAO PF01266.19 KPI42338.1 - 4.6e-61 206.6 0.3 8.2e-61 205.8 0.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI42338.1 - 2.2e-05 24.4 0.2 0.042 13.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI42338.1 - 0.00015 21.7 0.7 0.00041 20.3 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KPI42338.1 - 0.067 13.5 0.1 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI42338.1 - 0.1 12.3 0.7 0.49 10.1 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KPI42338.1 - 0.14 10.7 0.7 0.22 10.0 0.5 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Abhydrolase_6 PF12697.2 KPI42339.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 KPI42339.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) ECH PF00378.15 KPI42340.1 - 2.4e-13 49.8 0.0 6.3e-12 45.1 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family adh_short PF00106.20 KPI42341.1 - 3.8e-15 56.1 0.2 3e-14 53.2 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI42341.1 - 1.8e-08 34.4 0.0 5.6e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI42341.1 - 1.3e-05 24.9 0.0 0.0024 17.5 0.0 2.2 2 0 0 2 2 2 2 KR domain UCR_TM PF02921.9 KPI42341.1 - 0.038 14.2 0.2 0.075 13.2 0.1 1.4 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region SH3_1 PF00018.23 KPI42341.1 - 0.096 12.0 0.2 0.22 10.9 0.2 1.6 1 0 0 1 1 1 0 SH3 domain Peptidase_C54 PF03416.14 KPI42341.1 - 0.12 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C54 Aminotran_5 PF00266.14 KPI42342.1 - 6e-25 87.7 0.0 1.3e-17 63.6 0.0 2.2 1 1 0 2 2 2 2 Aminotransferase class-V TYW3 PF02676.9 KPI42343.1 - 2e-56 190.3 0.0 2.7e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 ArgJ PF01960.13 KPI42343.1 - 0.021 13.2 0.0 0.031 12.7 0.0 1.1 1 0 0 1 1 1 0 ArgJ family Pyridox_oxase_2 PF12766.2 KPI42344.1 - 2.2e-19 69.6 0.0 5.5e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Bax1-I PF01027.15 KPI42345.1 - 7.4e-37 126.9 26.8 1.4e-33 116.2 18.6 2.0 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2910 PF11139.3 KPI42345.1 - 0.036 13.2 0.2 0.036 13.2 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2910) Cation_ATPase_C PF00689.16 KPI42345.1 - 2.5 7.5 17.4 54 3.2 12.0 2.2 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus PrgI PF12666.2 KPI42345.1 - 2.9 8.1 12.7 0.97 9.6 0.4 2.9 1 1 2 3 3 3 0 PrgI family protein 2TM PF13239.1 KPI42345.1 - 5.9 7.0 19.6 1.6 8.8 2.4 2.7 3 0 0 3 3 3 0 2TM domain TRAPP PF04051.11 KPI42346.1 - 4.5e-24 84.6 0.0 6.4e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component FUN14 PF04930.10 KPI42347.1 - 1.7e-09 37.8 1.9 4.4e-09 36.5 1.3 1.7 1 1 0 1 1 1 1 FUN14 family Aph-1 PF06105.7 KPI42347.1 - 0.3 10.2 2.3 0.44 9.7 1.6 1.5 1 1 0 1 1 1 0 Aph-1 protein DUF3918 PF13056.1 KPI42347.1 - 9.1 5.6 12.3 2.1 7.7 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3918) AAA_27 PF13514.1 KPI42349.1 - 0.014 13.1 0.6 0.016 12.8 0.4 1.1 1 0 0 1 1 1 0 AAA domain SCF PF02404.10 KPI42349.1 - 0.071 12.2 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Stem cell factor CENP-F_leu_zip PF10473.4 KPI42349.1 - 0.072 12.9 1.2 0.23 11.3 0.8 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC155 PF14662.1 KPI42349.1 - 0.22 11.1 3.2 1.4 8.4 2.2 2.2 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 DivIC PF04977.10 KPI42349.1 - 0.35 10.4 1.5 0.88 9.0 0.6 1.9 1 1 1 2 2 2 0 Septum formation initiator Spt4 PF06093.8 KPI42350.1 - 4.9e-29 100.0 0.0 5.9e-29 99.7 0.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Thioredoxin_2 PF13098.1 KPI42350.1 - 0.03 14.5 0.0 0.041 14.0 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain FAD_binding_3 PF01494.14 KPI42351.1 - 2.2e-42 145.4 0.0 3.2e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI42351.1 - 2.6e-07 29.8 0.0 0.0069 15.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KPI42351.1 - 0.00013 21.1 0.4 0.00082 18.5 0.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KPI42351.1 - 0.00026 21.1 0.1 0.24 11.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI42351.1 - 0.00041 20.3 0.1 0.0016 18.4 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI42351.1 - 0.00054 18.9 0.2 0.031 13.1 0.1 2.1 1 1 1 2 2 2 1 FAD binding domain Thi4 PF01946.12 KPI42351.1 - 0.0008 18.5 0.1 0.0021 17.2 0.0 1.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KPI42351.1 - 0.0011 17.5 0.2 0.0042 15.6 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KPI42351.1 - 0.0014 18.5 0.0 0.0039 17.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI42351.1 - 0.0044 16.0 1.4 0.067 12.1 0.1 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.22 KPI42351.1 - 0.0049 17.2 0.0 1.9 8.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI42351.1 - 0.098 12.4 2.1 0.79 9.4 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KPI42351.1 - 0.1 11.1 0.3 2.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Mqo PF06039.10 KPI42351.1 - 0.11 10.6 0.0 0.17 10.0 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) MIF4G_like PF09088.6 KPI42352.1 - 3.4e-73 245.1 0.1 5.6e-73 244.4 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 KPI42352.1 - 1.4e-37 129.2 0.0 2.2e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 KPI42352.1 - 0.00011 21.7 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain zf-RING_2 PF13639.1 KPI42353.1 - 1.5e-12 47.1 6.3 2.4e-12 46.4 4.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KPI42353.1 - 1.4e-05 25.0 2.8 2.6e-05 24.2 1.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KPI42353.1 - 2.4e-05 24.2 4.4 3.9e-05 23.5 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI42353.1 - 4.7e-05 22.9 2.9 7.9e-05 22.2 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI42353.1 - 0.00016 21.2 2.8 0.00026 20.6 2.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KPI42353.1 - 0.00019 21.0 2.0 0.0003 20.3 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KPI42353.1 - 0.0035 17.1 1.5 0.007 16.1 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2382 PF09557.5 KPI42353.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2382) zf-P11 PF03854.9 KPI42353.1 - 0.35 10.3 2.9 0.64 9.5 2.0 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.1 KPI42353.1 - 0.44 10.1 2.0 0.74 9.4 1.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 KPI42353.1 - 0.46 10.5 2.8 0.99 9.4 1.9 1.6 1 0 0 1 1 1 0 RING-like domain CMAS PF02353.15 KPI42355.1 - 1.1e-59 201.7 0.0 1.4e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KPI42355.1 - 1.3e-11 44.4 0.0 2.3e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI42355.1 - 1.6e-08 34.9 0.0 7.4e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI42355.1 - 0.0054 17.0 0.0 0.02 15.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI42355.1 - 0.0058 17.0 0.0 0.018 15.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI42355.1 - 0.0095 15.9 0.0 0.023 14.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI42355.1 - 0.017 15.6 0.1 0.11 13.1 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KPI42355.1 - 0.046 13.0 0.1 0.091 12.1 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.8 KPI42355.1 - 0.083 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.14 KPI42355.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KPI42355.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 KPI42356.1 - 3.6e-25 88.4 23.4 2.1e-22 79.3 9.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4234 PF14018.1 KPI42356.1 - 0.1 12.3 0.9 0.38 10.5 0.3 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) NAC PF01849.13 KPI42357.1 - 3.9e-21 74.3 0.2 8e-21 73.3 0.1 1.5 1 0 0 1 1 1 1 NAC domain Geminin PF07412.7 KPI42357.1 - 0.053 13.2 1.0 0.081 12.6 0.7 1.4 1 0 0 1 1 1 0 Geminin DUF601 PF04642.7 KPI42358.1 - 0.97 8.7 4.2 1.7 7.9 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF601 PLDc_2 PF13091.1 KPI42359.1 - 1.3e-13 50.7 0.0 7.5e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KPI42359.1 - 6e-07 29.0 0.3 0.034 13.9 0.0 3.3 3 0 0 3 3 3 3 Phospholipase D Active site motif Virulence_RhuM PF13310.1 KPI42359.1 - 0.062 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Virulence protein RhuM family Abhydrolase_1 PF00561.15 KPI42360.1 - 2e-21 76.6 0.1 2.9e-20 72.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI42360.1 - 3e-13 50.1 1.3 6.2e-12 45.8 0.9 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KPI42360.1 - 0.00012 21.5 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KPI42360.1 - 0.027 14.2 0.1 8.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Solute_trans_a PF03619.11 KPI42361.1 - 1.9e-60 204.5 17.8 2.4e-60 204.1 12.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Tn7_Tnp_TnsA_C PF08721.6 KPI42361.1 - 0.04 13.9 0.0 3.6 7.6 0.0 2.7 3 0 0 3 3 3 0 TnsA endonuclease C terminal Brr6_like_C_C PF10104.4 KPI42361.1 - 3.3 7.2 9.3 0.48 9.9 0.4 2.6 2 1 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain Usp PF00582.21 KPI42362.1 - 5.2e-09 36.4 2.5 1.3e-05 25.3 0.0 3.0 3 0 0 3 3 3 2 Universal stress protein family Pkinase PF00069.20 KPI42363.1 - 4.3e-65 219.4 0.0 7.7e-39 133.3 0.0 3.8 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KPI42363.1 - 1.9e-35 122.2 0.0 5e-17 61.8 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 KPI42363.1 - 5.7e-14 51.9 0.2 1.7e-13 50.4 0.1 1.9 1 0 0 1 1 1 1 RWD domain HGTP_anticodon2 PF12745.2 KPI42363.1 - 4.7e-12 45.6 0.0 4.7e-12 45.6 0.0 2.7 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.1 KPI42363.1 - 2.1e-10 40.1 0.0 2.1e-10 40.1 0.0 2.6 3 0 0 3 3 3 1 Histidyl-tRNA synthetase APH PF01636.18 KPI42363.1 - 0.0077 15.9 3.0 0.024 14.3 0.0 3.1 4 0 0 4 4 4 1 Phosphotransferase enzyme family Sugar_tr PF00083.19 KPI42364.1 - 1.4e-92 310.7 18.6 1.4e-92 310.7 12.9 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI42364.1 - 7.5e-26 90.6 38.0 1e-21 77.0 4.3 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KPI42365.1 - 6.2e-08 32.0 0.0 0.00064 18.8 0.0 3.1 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 KPI42365.1 - 9.5e-07 28.0 0.0 0.01 14.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KPI42365.1 - 0.0023 18.0 0.0 0.0046 17.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI42365.1 - 0.0076 16.2 0.0 0.025 14.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI42365.1 - 0.11 11.2 1.4 0.19 10.5 0.9 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KPI42365.1 - 0.23 11.3 0.4 0.48 10.2 0.3 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MIP PF00230.15 KPI42366.1 - 1.2e-53 181.9 2.3 1.5e-53 181.5 1.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein MCM PF00493.18 KPI42367.1 - 1e-134 448.5 0.1 1.5e-134 448.0 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KPI42367.1 - 1.2e-19 71.0 0.6 6.1e-19 68.6 0.1 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KPI42367.1 - 3.7e-07 29.5 0.0 1.4e-05 24.3 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KPI42367.1 - 0.00072 19.3 0.0 0.0047 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KPI42367.1 - 0.0028 17.1 0.0 0.006 16.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KPI42367.1 - 0.0055 16.3 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MUG113 PF13455.1 KPI42369.1 - 4.1e-29 100.8 0.1 1.1e-28 99.5 0.1 1.7 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KPI42369.1 - 1.4e-19 70.2 0.0 3.4e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain RRM_1 PF00076.17 KPI42371.1 - 5.2e-16 58.0 0.0 9e-16 57.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI42371.1 - 6e-11 42.1 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI42371.1 - 5.1e-05 23.0 0.0 8.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rep_4 PF05797.6 KPI42371.1 - 2.3 6.8 6.7 3.4 6.2 4.6 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) AA_permease_2 PF13520.1 KPI42372.1 - 3.4e-47 160.9 65.1 3.5e-46 157.6 45.0 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI42372.1 - 3.8e-24 84.8 48.0 7.4e-24 83.9 33.3 1.5 1 1 0 1 1 1 1 Amino acid permease Phage_CII PF05269.6 KPI42372.1 - 0.0056 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Bacteriophage CII protein Sarcoglycan_1 PF04790.8 KPI42372.1 - 0.14 11.3 0.6 0.32 10.1 0.4 1.5 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein CAF1 PF04857.15 KPI42374.1 - 7e-65 218.9 0.1 9.3e-65 218.5 0.1 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease Patatin PF01734.17 KPI42375.1 - 1.1e-23 84.2 0.0 7.1e-23 81.6 0.0 2.2 2 1 0 2 2 2 1 Patatin-like phospholipase Sugar_tr PF00083.19 KPI42377.1 - 1.4e-106 356.7 31.4 1.9e-106 356.3 21.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI42377.1 - 1.9e-26 92.6 61.9 3.3e-25 88.5 24.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI42377.1 - 5.6e-06 25.0 34.3 0.00027 19.4 5.0 3.3 3 1 0 3 3 3 2 MFS/sugar transport protein Dicty_REP PF05086.7 KPI42378.1 - 0.04 11.6 4.8 0.034 11.9 3.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 KPI42378.1 - 0.069 12.8 11.0 0.12 12.1 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 KPI42378.1 - 0.13 10.1 10.9 0.14 10.1 7.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Med3 PF11593.3 KPI42378.1 - 1.9 7.6 8.2 1.9 7.6 5.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PmbA_TldD PF01523.11 KPI42379.1 - 0.14 11.4 0.2 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 Putative modulator of DNA gyrase AAA PF00004.24 KPI42380.1 - 9e-47 158.5 0.0 8e-41 139.3 0.0 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KPI42380.1 - 1.8e-11 44.3 0.0 9.8e-05 22.4 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 KPI42380.1 - 9e-08 31.9 0.3 0.00057 19.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KPI42380.1 - 1.3e-06 28.6 0.0 0.037 14.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KPI42380.1 - 3.5e-05 23.9 0.0 0.35 11.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 KPI42380.1 - 4e-05 23.6 0.0 0.39 10.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KPI42380.1 - 0.00011 22.1 0.0 0.029 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KPI42380.1 - 0.00026 20.4 0.3 0.88 8.9 0.0 3.1 2 1 1 3 3 3 2 AAA domain DUF815 PF05673.8 KPI42380.1 - 0.00027 19.9 0.0 0.18 10.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Rad17 PF03215.10 KPI42380.1 - 0.00066 18.4 0.0 0.042 12.5 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 KPI42380.1 - 0.00075 20.3 0.0 0.58 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KPI42380.1 - 0.0019 17.2 0.0 0.019 14.0 0.0 2.5 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KPI42380.1 - 0.0068 15.1 0.1 0.014 14.1 0.0 1.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA_2 PF07724.9 KPI42380.1 - 0.0072 16.2 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.7 KPI42380.1 - 0.017 14.7 0.3 17 5.0 0.0 3.7 2 2 2 4 4 4 0 NACHT domain Mg_chelatase PF01078.16 KPI42380.1 - 0.022 13.9 0.4 1.1 8.3 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KPI42380.1 - 0.028 13.8 0.4 0.99 8.7 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 KPI42380.1 - 0.038 14.0 0.0 0.41 10.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 KPI42380.1 - 0.048 13.2 0.0 0.37 10.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KPI42380.1 - 0.065 12.9 0.0 18 4.9 0.0 2.9 3 1 1 4 4 3 0 Archaeal ATPase AAA_29 PF13555.1 KPI42380.1 - 0.095 12.2 0.0 0.42 10.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 KPI42380.1 - 0.1 12.0 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain CDC48_N PF02359.13 KPI42380.1 - 0.1 12.5 0.0 0.33 10.9 0.0 1.9 1 1 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_33 PF13671.1 KPI42380.1 - 0.14 12.0 0.0 4.5 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cutinase PF01083.17 KPI42381.1 - 1.3e-40 139.0 0.8 1.6e-40 138.7 0.6 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KPI42381.1 - 0.0059 16.0 0.2 0.0094 15.3 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain Fungal_trans PF04082.13 KPI42382.1 - 5.9e-16 58.1 0.9 9.9e-16 57.3 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain dCMP_cyt_deam_1 PF00383.17 KPI42383.1 - 2.4e-24 84.9 0.0 3.1e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KPI42383.1 - 0.0041 16.9 1.5 0.15 11.9 0.1 2.2 1 1 0 2 2 2 2 Bd3614-like deaminase Solute_trans_a PF03619.11 KPI42384.1 - 3.2e-81 272.6 18.6 3.8e-81 272.4 12.9 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha 5_nucleotid_C PF02872.13 KPI42386.1 - 2.9e-36 124.8 0.3 7.1e-36 123.5 0.1 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KPI42386.1 - 1.4e-10 40.9 0.2 2.4e-10 40.1 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YmdB PF13277.1 KPI42386.1 - 0.038 13.0 0.0 0.074 12.0 0.0 1.5 1 0 0 1 1 1 0 YmdB-like protein FAD_binding_3 PF01494.14 KPI42387.1 - 5.7e-79 265.7 0.0 7.1e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KPI42387.1 - 8.9e-48 162.0 0.0 1.5e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 KPI42387.1 - 2.2e-05 23.5 0.3 0.16 10.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI42387.1 - 0.0012 17.7 0.9 0.037 12.8 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KPI42387.1 - 0.014 14.5 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 KPI42387.1 - 0.058 12.4 1.7 0.23 10.4 1.1 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Peptidase_C33 PF05412.7 KPI42387.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase Pyr_redox_2 PF07992.9 KPI42387.1 - 0.092 12.6 0.1 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI42387.1 - 0.12 12.4 0.6 0.53 10.3 0.1 2.4 2 1 1 3 3 3 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 KPI42387.1 - 0.12 11.1 0.1 5.1 5.8 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.17 KPI42387.1 - 0.27 10.0 1.0 1.3 7.8 0.7 1.9 1 1 0 1 1 1 0 Glucose inhibited division protein A p450 PF00067.17 KPI42388.1 - 3.8e-49 167.4 0.0 5.7e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1996 PF09362.5 KPI42389.1 - 1.3e-67 227.9 1.4 2.8e-67 226.8 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 KPI42389.1 - 1.1e-52 175.8 53.6 9.7e-15 54.2 9.0 4.8 4 0 0 4 4 4 4 WSC domain Med15 PF09606.5 KPI42390.1 - 6.4 4.8 47.7 10 4.1 33.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Abhydrolase_6 PF12697.2 KPI42391.1 - 1.3e-12 48.0 0.2 2e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI42391.1 - 2.9e-10 40.0 0.0 5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI42391.1 - 2.1e-07 30.3 0.0 0.0061 15.7 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KPI42391.1 - 2.7e-07 30.3 0.2 6.6e-07 29.1 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KPI42391.1 - 0.00015 21.4 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DLH PF01738.13 KPI42391.1 - 0.00028 20.2 0.0 0.17 11.1 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 KPI42391.1 - 0.00036 20.1 0.0 0.0016 18.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 KPI42391.1 - 0.00088 19.0 0.0 0.0075 15.9 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.15 KPI42391.1 - 0.039 14.1 0.0 0.1 12.7 0.0 1.7 1 1 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 KPI42391.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.7 KPI42391.1 - 0.13 10.7 0.0 0.2 10.0 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S10 PF00450.17 KPI42391.1 - 0.18 10.8 0.0 1.3 8.1 0.0 2.0 2 0 0 2 2 2 0 Serine carboxypeptidase PLA2_B PF01735.13 KPI42392.1 - 8.2e-100 334.2 0.1 1e-99 334.0 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain RIP PF00161.14 KPI42392.1 - 0.05 12.7 0.0 0.14 11.3 0.0 1.6 2 0 0 2 2 2 0 Ribosome inactivating protein Erf4 PF10256.4 KPI42393.1 - 1.2e-31 108.9 0.0 1.6e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Sugar_tr PF00083.19 KPI42394.1 - 5.4e-90 302.1 31.0 6.6e-90 301.8 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI42394.1 - 7.2e-19 67.7 33.7 7.2e-19 67.7 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.7 KPI42394.1 - 0.1 12.1 1.2 0.24 10.8 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF697) OATP PF03137.15 KPI42394.1 - 0.43 8.5 11.6 0.015 13.3 2.4 2.2 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family zf-C2H2_4 PF13894.1 KPI42395.1 - 0.00057 20.0 14.8 0.075 13.3 1.2 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI42395.1 - 0.041 14.2 1.0 0.041 14.2 0.7 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KPI42395.1 - 0.086 12.9 2.7 0.59 10.2 0.2 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-FCS PF06467.9 KPI42395.1 - 0.11 12.1 0.2 3.5 7.3 0.0 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_jaz PF12171.3 KPI42395.1 - 0.96 9.6 9.0 0.042 13.9 1.8 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Pkinase PF00069.20 KPI42396.1 - 2.2e-62 210.5 0.0 2.6e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI42396.1 - 8.1e-25 87.3 0.0 1.1e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI42396.1 - 1.9e-07 30.3 0.0 8e-07 28.2 0.0 1.8 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 KPI42396.1 - 0.0006 19.6 0.1 0.0071 16.0 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KPI42396.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Sec63 PF02889.11 KPI42397.1 - 3e-183 608.1 0.3 2.7e-105 352.0 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KPI42397.1 - 3.8e-55 185.9 0.1 6.8e-30 103.7 0.0 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 KPI42397.1 - 1.3e-17 64.2 0.0 4.6e-08 33.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KPI42397.1 - 4.8e-11 42.3 0.0 2.8e-09 36.7 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KPI42397.1 - 9.9e-08 32.1 0.0 0.00022 21.3 0.0 3.3 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 KPI42397.1 - 0.0002 20.6 0.0 0.046 12.9 0.0 2.9 3 0 0 3 3 3 1 PhoH-like protein FtsK_SpoIIIE PF01580.13 KPI42397.1 - 0.0042 16.5 0.0 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.1 KPI42397.1 - 0.024 14.3 0.0 1.8 8.3 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain Spo12 PF05032.7 KPI42398.1 - 1.4e-06 27.8 0.3 3.4e-06 26.5 0.2 1.7 1 0 0 1 1 1 1 Spo12 family DUF2263 PF10021.4 KPI42399.1 - 6.4e-24 84.6 0.0 1.8e-23 83.1 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 KPI42399.1 - 0.0025 17.7 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Macro domain DUF2015 PF09435.5 KPI42401.1 - 2.9e-40 137.0 0.0 3.2e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Rep_fac_C PF08542.6 KPI42402.1 - 1.8e-20 72.7 0.0 3.4e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KPI42402.1 - 5e-11 42.5 0.0 5.2e-09 35.9 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KPI42402.1 - 2.3e-10 40.7 0.1 4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KPI42402.1 - 7.7e-07 29.0 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KPI42402.1 - 9.8e-07 27.8 0.0 0.019 13.6 0.0 3.0 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 KPI42402.1 - 1.4e-05 25.2 0.1 0.00044 20.2 0.0 2.5 1 1 2 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.13 KPI42402.1 - 1.6e-05 24.5 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.7 KPI42402.1 - 2e-05 23.7 0.0 7.4e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KPI42402.1 - 3.5e-05 23.9 0.2 0.0089 16.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KPI42402.1 - 0.00014 21.4 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KPI42402.1 - 0.00091 18.7 0.2 0.4 10.0 0.0 2.4 1 1 1 2 2 2 2 AAA-like domain DNA_pol3_delta PF06144.8 KPI42402.1 - 0.0015 18.1 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 KPI42402.1 - 0.0016 17.6 0.0 0.014 14.5 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KPI42402.1 - 0.0033 17.1 0.0 0.0069 16.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain ArgK PF03308.11 KPI42402.1 - 0.0074 15.0 0.1 0.02 13.6 0.0 1.7 1 1 0 1 1 1 1 ArgK protein AAA_11 PF13086.1 KPI42402.1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KPI42402.1 - 0.011 15.4 0.3 0.042 13.5 0.1 2.0 1 1 1 2 2 2 0 NTPase AAA_25 PF13481.1 KPI42402.1 - 0.02 14.3 0.1 0.15 11.4 0.1 2.3 1 1 1 2 2 2 0 AAA domain DNA_pol3_gamma3 PF12169.3 KPI42402.1 - 0.02 14.6 0.4 3.1 7.5 0.0 2.6 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III DEAD PF00270.24 KPI42402.1 - 0.031 13.7 0.1 0.56 9.6 0.0 2.4 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.1 KPI42402.1 - 0.039 14.2 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 KPI42402.1 - 0.041 13.0 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.13 KPI42402.1 - 0.043 13.2 0.0 0.087 12.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_31 PF13614.1 KPI42402.1 - 0.05 13.5 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KPI42402.1 - 0.098 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KPI42402.1 - 0.099 12.3 0.1 0.34 10.6 0.0 2.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF1469 PF07332.6 KPI42403.1 - 0.096 12.4 0.7 0.2 11.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) RRM_1 PF00076.17 KPI42405.1 - 1.1e-14 53.8 0.0 1.6e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI42405.1 - 2.3e-12 46.6 0.0 3.4e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI42405.1 - 0.00028 20.6 0.0 0.00047 19.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GFO_IDH_MocA PF01408.17 KPI42406.1 - 4.2e-19 69.2 0.0 1.2e-18 67.7 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KPI42406.1 - 1.3e-05 25.0 0.0 2.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KPI42406.1 - 0.0039 17.5 0.0 0.0082 16.5 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain PPR_3 PF13812.1 KPI42407.1 - 2.7e-12 45.9 3.3 0.0057 16.8 0.0 6.5 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 KPI42407.1 - 5.7e-09 35.8 0.0 0.017 15.0 0.0 4.6 3 1 1 4 4 4 4 PPR repeat family PPR PF01535.15 KPI42407.1 - 1.1e-07 31.3 0.0 0.01 15.7 0.0 5.1 5 0 0 5 5 5 2 PPR repeat PRO8NT PF08082.6 KPI42407.1 - 0.0082 15.7 0.2 2.7 7.6 0.0 2.4 2 0 0 2 2 2 2 PRO8NT (NUC069), PrP8 N-terminal domain PPR_1 PF12854.2 KPI42407.1 - 0.11 12.0 0.0 4.3 6.9 0.0 3.1 3 0 0 3 3 3 0 PPR repeat DUF972 PF06156.8 KPI42408.1 - 0.0041 17.4 0.5 0.18 12.1 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF972) HALZ PF02183.13 KPI42408.1 - 0.053 13.2 3.1 0.076 12.7 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1664 PF07889.7 KPI42408.1 - 0.15 11.9 2.7 0.67 9.7 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 KPI42408.1 - 0.4 10.8 5.4 43 4.3 3.8 2.6 1 1 0 1 1 1 0 Syntaxin Cep57_CLD_2 PF14197.1 KPI42408.1 - 7 6.6 7.0 8.2 6.4 0.7 3.0 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 IDO PF01231.13 KPI42409.1 - 1.7e-88 296.8 0.0 2.2e-88 296.5 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 KPI42409.1 - 0.064 11.7 0.0 0.093 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) MFS_1 PF07690.11 KPI42410.1 - 4.4e-38 130.8 11.2 4.4e-38 130.8 7.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI42410.1 - 1.8e-14 53.1 12.5 8.5e-14 50.9 0.2 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 KPI42410.1 - 6.3e-10 38.0 8.9 4.5e-06 25.3 0.5 3.5 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 KPI42410.1 - 0.00067 19.4 0.1 0.0081 15.9 0.1 2.6 2 0 0 2 2 2 1 MFS_1 like family Folate_carrier PF01770.13 KPI42410.1 - 0.012 14.1 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 0 Reduced folate carrier FAA_hydrolase PF01557.13 KPI42411.1 - 5.1e-52 176.4 0.0 3.9e-51 173.5 0.0 1.9 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Peptidase_S8 PF00082.17 KPI42412.1 - 8.7e-19 67.7 0.0 1.6e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Subtilase family TPR_11 PF13414.1 KPI42412.1 - 0.013 15.1 0.9 0.027 14.1 0.6 1.5 1 0 0 1 1 1 0 TPR repeat TPR_16 PF13432.1 KPI42412.1 - 0.075 13.7 0.0 25 5.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat FAA_hydrolase PF01557.13 KPI42413.1 - 1e-60 204.8 0.0 2e-60 203.9 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_6 PF12697.2 KPI42413.1 - 2.6e-36 125.6 1.0 3.5e-36 125.2 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI42413.1 - 5.2e-18 65.1 0.3 2.5e-16 59.7 0.2 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI42413.1 - 1.3e-14 54.3 0.3 1.6e-10 40.9 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 KPI42413.1 - 4.4e-05 23.1 0.4 0.00015 21.4 0.2 1.8 1 1 1 2 2 2 1 Serine hydrolase Hydrolase_4 PF12146.3 KPI42413.1 - 0.00017 21.3 0.1 0.00046 19.9 0.0 1.8 2 0 0 2 2 1 1 Putative lysophospholipase Ndr PF03096.9 KPI42413.1 - 0.0013 17.2 0.0 0.0019 16.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.15 KPI42413.1 - 0.051 13.8 0.1 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_8 PF06259.7 KPI42413.1 - 0.082 12.4 2.9 0.17 11.3 0.3 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase Esterase PF00756.15 KPI42413.1 - 0.098 12.0 0.1 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF2437 PF10370.4 KPI42413.1 - 0.13 12.6 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2437) DUF1680 PF07944.7 KPI42414.1 - 9.1e-106 354.1 0.0 1.1e-105 353.9 0.0 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) DUF1408 PF07193.6 KPI42414.1 - 0.077 12.5 0.0 0.31 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1408) Epimerase PF01370.16 KPI42415.1 - 1.2e-24 87.0 0.0 1.8e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI42415.1 - 1.5e-08 33.7 0.0 4.1e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KPI42415.1 - 2.7e-07 30.7 0.2 1.6e-06 28.2 0.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KPI42415.1 - 4.8e-07 28.9 0.0 8.9e-07 28.0 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KPI42415.1 - 7.2e-07 28.3 0.0 1.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KPI42415.1 - 0.00019 20.4 0.1 0.00043 19.2 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KPI42415.1 - 0.0027 17.6 0.4 0.0027 17.6 0.3 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 KPI42415.1 - 0.0093 15.2 0.0 0.045 13.0 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Abhydrolase_6 PF12697.2 KPI42417.1 - 2.7e-39 135.3 0.0 3.2e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI42417.1 - 3.3e-26 92.2 0.0 3.9e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI42417.1 - 1.2e-24 86.7 0.2 2.2e-16 59.9 0.1 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KPI42417.1 - 2.6e-12 46.4 0.3 4.6e-12 45.6 0.2 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KPI42417.1 - 7.6e-09 35.0 0.1 0.0019 17.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KPI42417.1 - 6e-05 22.5 0.0 0.00018 21.0 0.0 1.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 KPI42417.1 - 0.00044 19.7 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 KPI42417.1 - 0.002 17.4 0.0 0.025 13.8 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family LIP PF03583.9 KPI42417.1 - 0.004 16.4 0.0 0.0077 15.4 0.0 1.5 1 0 0 1 1 1 1 Secretory lipase Ser_hydrolase PF06821.8 KPI42417.1 - 0.042 13.4 0.0 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase Ndr PF03096.9 KPI42417.1 - 0.049 12.1 0.0 0.077 11.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family FSH1 PF03959.8 KPI42417.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.6 KPI42417.1 - 0.079 12.6 0.1 0.18 11.5 0.1 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 KPI42417.1 - 0.084 11.3 0.1 0.56 8.6 0.0 2.0 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) PAF-AH_p_II PF03403.8 KPI42417.1 - 0.11 10.8 0.0 7.3 4.7 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF915 PF06028.6 KPI42417.1 - 0.13 11.2 0.0 0.37 9.8 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) bZIP_1 PF00170.16 KPI42419.1 - 0.00035 20.4 0.7 0.00081 19.2 0.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 KPI42419.1 - 0.02 14.4 0.8 0.093 12.3 0.1 2.2 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain DUF3037 PF11236.3 KPI42419.1 - 0.14 12.2 0.0 0.48 10.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Sad1_UNC PF07738.8 KPI42420.1 - 1.4e-33 115.5 0.0 3.4e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal MFS_1 PF07690.11 KPI42421.1 - 3.2e-28 98.4 19.8 3.2e-28 98.4 13.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 KPI42421.1 - 3.8e-05 22.3 7.5 0.00062 18.3 0.4 3.4 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like Kin17_mid PF10357.4 KPI42422.1 - 1.6e-49 166.7 1.7 2.9e-49 165.9 1.2 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 KPI42422.1 - 0.00012 22.0 1.4 0.00025 21.0 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KPI42422.1 - 0.001 19.1 2.1 0.0021 18.1 1.4 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Phage_min_cap2 PF06152.6 KPI42422.1 - 0.021 13.7 1.0 0.043 12.7 0.7 1.4 1 0 0 1 1 1 0 Phage minor capsid protein 2 zf-C2H2_2 PF12756.2 KPI42422.1 - 0.024 14.7 0.4 0.024 14.7 0.3 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RRM_1 PF00076.17 KPI42423.1 - 2.8e-33 113.3 0.0 1.7e-16 59.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI42423.1 - 3.6e-19 68.4 0.0 3.5e-10 39.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI42423.1 - 5.9e-15 54.8 0.0 5.8e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KPI42423.1 - 0.034 13.6 0.1 10 5.7 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Aconitase PF00330.15 KPI42424.1 - 3.1e-71 240.2 0.1 3.5e-45 154.3 0.0 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KPI42424.1 - 3.6e-24 85.3 0.0 9e-24 84.0 0.0 1.7 2 0 0 2 2 2 1 Aconitase C-terminal domain HET PF06985.6 KPI42425.1 - 9.1e-23 80.9 0.3 1.9e-22 79.9 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 KPI42426.1 - 2.6e-17 63.2 0.0 5e-17 62.3 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI42426.1 - 1.6e-08 34.4 0.1 2.3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI42426.1 - 8.4e-05 22.1 0.0 0.00035 20.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KPI42426.1 - 0.00039 20.2 0.0 0.00061 19.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KPI42426.1 - 0.0018 18.2 0.2 0.0036 17.3 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KPI42426.1 - 0.0079 15.2 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.10 KPI42426.1 - 0.019 13.9 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 KPI42426.1 - 0.066 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.19 KPI42427.1 - 7.2e-63 212.7 19.7 8.3e-63 212.5 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI42427.1 - 2.3e-09 36.4 26.8 2.3e-09 36.4 18.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily His_Phos_1 PF00300.17 KPI42428.1 - 1.9e-13 50.8 2.7 4.7e-13 49.5 0.0 2.5 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF964 PF06133.6 KPI42428.1 - 0.099 12.6 1.2 0.2 11.6 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF964) Brix PF04427.13 KPI42429.1 - 1e-37 129.6 0.0 1.4e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain Cwf_Cwc_15 PF04889.7 KPI42429.1 - 0.97 9.0 8.9 1.7 8.2 6.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CLTH PF10607.4 KPI42430.1 - 7.6e-25 87.3 0.0 1.5e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KPI42430.1 - 0.0068 16.1 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 LisH Snf7 PF03357.16 KPI42430.1 - 0.0073 15.7 0.2 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Snf7 CENP-F_leu_zip PF10473.4 KPI42430.1 - 0.037 13.8 1.0 0.077 12.8 0.7 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3829 PF12889.2 KPI42430.1 - 0.18 10.9 1.1 0.28 10.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF1077 PF06417.7 KPI42432.1 - 2.5e-49 165.7 1.1 3.3e-49 165.4 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) ABA_GPCR PF12430.3 KPI42433.1 - 1.3e-44 151.6 0.9 1.3e-44 151.6 0.7 1.9 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 KPI42433.1 - 2.4e-18 65.9 0.0 7.1e-18 64.4 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) DUF2798 PF11391.3 KPI42433.1 - 5.1 6.9 11.8 0.27 10.9 0.5 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2798) Methyltransf_16 PF10294.4 KPI42434.1 - 0.00019 20.9 0.0 0.036 13.5 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase 2OG-FeII_Oxy_2 PF13532.1 KPI42435.1 - 1.3e-10 41.3 0.0 3.9e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lyase_1 PF00206.15 KPI42437.1 - 8.8e-90 301.0 0.0 1.2e-89 300.6 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 KPI42437.1 - 1.2e-25 89.3 0.1 4e-25 87.6 0.0 2.0 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal EST1_DNA_bind PF10373.4 KPI42439.1 - 4.1e-10 39.3 0.1 1.4e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain DUF605 PF04652.11 KPI42439.1 - 0.79 9.0 9.6 1.2 8.4 6.6 1.2 1 0 0 1 1 1 0 Vta1 like PBD PF00786.23 KPI42440.1 - 9e-05 22.8 0.1 0.00051 20.4 0.1 2.4 1 0 0 1 1 1 1 P21-Rho-binding domain SRF-TF PF00319.13 KPI42441.1 - 1.3e-23 81.9 0.2 1.8e-23 81.5 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Herpes_LMP2 PF07415.6 KPI42441.1 - 2.1 6.8 5.7 3.2 6.2 4.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein GNVR PF13807.1 KPI42442.1 - 1.7 8.4 0.0 1.7 8.4 0.0 2.5 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase FSH1 PF03959.8 KPI42443.1 - 8.9e-21 74.3 0.0 1.1e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KPI42443.1 - 0.0013 18.2 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KPI42443.1 - 0.066 13.0 3.0 2.3 8.0 2.1 2.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family PUF PF00806.14 KPI42444.1 - 6.8e-56 182.7 5.9 4.9e-08 32.0 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat AMP-binding PF00501.23 KPI42445.1 - 1.6e-55 188.2 0.0 2e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI42445.1 - 4.9e-09 37.0 0.0 1.2e-08 35.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cas_VVA1548 PF09652.5 KPI42445.1 - 0.064 13.2 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Putative CRISPR-associated protein (Cas_VVA1548) HET PF06985.6 KPI42446.1 - 2.4e-29 102.2 0.1 8e-29 100.5 0.1 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF336 PF03928.9 KPI42447.1 - 1.5e-32 112.1 0.3 1.8e-32 111.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Zn_clus PF00172.13 KPI42448.1 - 1.9e-08 34.0 7.8 2.9e-08 33.4 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ACOX PF01756.14 KPI42449.1 - 9.2e-24 83.8 0.1 8.7e-22 77.4 0.0 2.5 1 1 1 2 2 2 2 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KPI42449.1 - 6.9e-22 78.0 0.4 1.6e-21 76.8 0.3 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KPI42449.1 - 7.8e-09 34.9 0.1 2e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KPI42449.1 - 5.3e-06 26.6 1.1 0.00027 21.0 0.0 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.11 KPI42450.1 - 5.4e-31 107.5 35.2 7.4e-31 107.1 24.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 KPI42450.1 - 0.0013 16.8 1.8 0.0013 16.8 1.2 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Mpv17_PMP22 PF04117.7 KPI42451.1 - 5e-18 64.4 2.7 1.4e-17 63.0 1.8 1.8 1 0 0 1 1 1 1 Mpv17 / PMP22 family Fungal_trans_2 PF11951.3 KPI42452.1 - 1.1e-20 73.5 2.0 1.8e-20 72.8 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.1 KPI42452.1 - 0.00029 20.9 0.0 0.00058 19.9 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI42452.1 - 0.031 13.6 0.0 0.073 12.4 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Isochorismatase PF00857.15 KPI42453.1 - 1.9e-07 31.1 0.0 3.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Spermine_synth PF01564.12 KPI42453.1 - 0.00014 20.8 0.0 0.00024 20.1 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 KPI42453.1 - 0.04 14.4 0.0 0.073 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF924 PF06041.6 KPI42454.1 - 3.5e-51 173.6 0.0 4.2e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Abhydrolase_1 PF00561.15 KPI42455.1 - 4.1e-47 160.6 0.0 5.4e-46 157.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI42455.1 - 1.2e-11 44.9 0.1 7.4e-11 42.3 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KPI42455.1 - 0.022 13.4 0.0 0.03 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KPI42455.1 - 0.025 14.3 0.3 0.16 11.7 0.2 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF410 PF04190.8 KPI42456.1 - 3e-39 135.1 0.0 2.7e-23 82.8 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF410) DUF1989 PF09347.5 KPI42457.1 - 2.9e-47 160.2 0.1 1e-46 158.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.16 KPI42457.1 - 6.2e-19 67.8 0.0 1e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 KPI42457.1 - 3.6e-05 23.2 0.0 5.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.4 KPI42457.1 - 0.089 10.8 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) NDUF_B12 PF08122.7 KPI42458.1 - 7.1e-15 54.4 1.3 9.4e-15 54.0 0.9 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family His_Phos_1 PF00300.17 KPI42459.1 - 1.5e-10 41.3 0.0 2.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Gag_p12 PF01141.13 KPI42460.1 - 4.1 7.6 10.1 0.37 10.9 2.6 2.1 1 1 0 2 2 2 0 Gag polyprotein, inner coat protein p12 adh_short_C2 PF13561.1 KPI42461.1 - 1.5e-27 96.8 0.0 1.8e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI42461.1 - 3.3e-23 82.4 0.1 9.6e-23 80.9 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI42461.1 - 0.00021 21.0 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI42461.1 - 0.033 13.6 0.2 0.077 12.4 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KPI42461.1 - 0.061 13.1 0.3 0.19 11.5 0.2 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Rapamycin_bind PF08771.6 KPI42461.1 - 0.079 13.0 0.0 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Rapamycin binding domain Acyl-CoA_ox_N PF14749.1 KPI42462.1 - 4e-17 62.6 1.1 5.9e-17 62.1 0.2 1.7 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KPI42462.1 - 1.6e-09 37.1 0.1 4.7e-09 35.6 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.14 KPI42462.1 - 2.3e-05 23.8 0.0 5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.19 KPI42462.1 - 0.00037 20.6 0.0 0.00085 19.4 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cu-oxidase_2 PF07731.9 KPI42463.1 - 3.6e-44 149.6 10.2 3.8e-38 130.1 1.9 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KPI42463.1 - 2.9e-40 136.6 5.9 4.2e-39 132.9 0.7 3.3 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 KPI42463.1 - 1.8e-36 125.4 1.8 2.9e-34 118.2 0.0 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 KPI42463.1 - 0.014 15.3 0.0 12 5.8 0.0 3.8 4 0 0 4 4 4 0 Cupredoxin-like domain E1_DerP2_DerF2 PF02221.10 KPI42463.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 ML domain Phosphodiest PF01663.17 KPI42465.1 - 4.7e-11 42.6 1.2 4.7e-11 42.6 0.9 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KPI42465.1 - 0.0013 18.0 0.1 0.0023 17.1 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KPI42465.1 - 0.0075 15.6 1.1 0.012 14.9 0.8 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Bacteriocin_IIc PF10439.4 KPI42465.1 - 2.5 8.3 7.4 7.2 6.8 5.1 1.8 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Ytp1 PF10355.4 KPI42466.1 - 2.7e-83 279.2 14.6 4.4e-83 278.6 10.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KPI42466.1 - 8.2e-29 99.2 0.9 8.2e-29 99.2 0.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) NRDE-2 PF08424.5 KPI42467.1 - 6.7e-65 219.0 0.9 2.9e-64 216.9 0.4 2.1 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KPI42467.1 - 0.021 15.4 0.4 14 6.6 0.0 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 KPI42467.1 - 0.061 14.0 0.1 0.38 11.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Mito_carr PF00153.22 KPI42468.1 - 1.3e-63 210.7 0.0 1.8e-20 72.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UBA_4 PF14555.1 KPI42469.1 - 2.4e-06 26.9 0.2 4.6e-06 26.0 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 KPI42469.1 - 0.022 14.5 0.1 0.066 13.0 0.1 1.7 1 0 0 1 1 1 0 UBA/TS-N domain GAS PF13851.1 KPI42469.1 - 0.17 11.0 2.9 2.6 7.2 0.1 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4140 PF13600.1 KPI42469.1 - 0.24 11.8 7.8 9.2 6.7 0.5 3.8 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) UIM PF02809.15 KPI42469.1 - 0.49 10.1 6.8 1.5 8.5 4.7 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif PAF-AH_p_II PF03403.8 KPI42470.1 - 6e-35 120.2 0.0 3.4e-34 117.7 0.0 1.9 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KPI42470.1 - 1.4e-05 24.9 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KPI42470.1 - 0.042 13.7 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase WD40 PF00400.27 KPI42471.1 - 1.3e-72 237.2 6.0 3.3e-11 42.5 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 KPI42471.1 - 8.3e-24 83.5 11.6 1.4e-23 82.8 8.1 1.4 1 0 0 1 1 1 1 Tup N-terminal Nbas_N PF15492.1 KPI42471.1 - 5.1e-05 22.5 0.0 0.1 11.6 0.0 3.0 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 KPI42471.1 - 0.00012 21.8 0.0 0.086 12.5 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KPI42471.1 - 0.0014 17.4 0.1 0.62 8.7 0.0 3.4 1 1 1 2 2 2 1 Nup133 N terminal like Nup160 PF11715.3 KPI42471.1 - 0.0053 14.9 0.2 2.2 6.3 0.0 2.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KPI42471.1 - 0.0068 14.7 0.2 0.042 12.1 0.2 1.9 1 1 0 2 2 2 1 Cytochrome D1 heme domain Gmad1 PF10647.4 KPI42471.1 - 0.015 14.6 0.0 0.11 11.8 0.0 2.0 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 KPI42471.1 - 0.32 10.3 5.5 3.7 6.9 0.0 4.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature SET PF00856.23 KPI42472.1 - 4.2e-21 75.9 1.8 2e-19 70.4 0.2 3.0 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.11 KPI42472.1 - 2.2e-14 53.5 3.3 2.2e-14 53.5 2.3 2.1 2 0 0 2 2 2 1 Pre-SET motif Metallothio_PEC PF02068.11 KPI42472.1 - 3.2 8.2 15.0 0.41 11.0 0.6 3.4 3 0 0 3 3 3 0 Plant PEC family metallothionein Fungal_trans PF04082.13 KPI42473.1 - 1.2e-14 53.8 0.3 1.2e-14 53.8 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Aminotran_3 PF00202.16 KPI42475.1 - 3.3e-100 335.2 0.0 4e-100 334.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Vps5 PF09325.5 KPI42476.1 - 6.1e-15 55.1 4.0 1.1e-14 54.3 2.8 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KPI42476.1 - 1.2e-08 34.6 0.0 2.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 KPI42476.1 - 0.063 12.5 0.2 0.14 11.3 0.0 1.7 2 1 0 2 2 2 0 WASP-binding domain of Sorting nexin protein TPR_12 PF13424.1 KPI42476.1 - 0.71 9.8 5.7 0.34 10.8 0.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Rsm22 PF09243.5 KPI42477.1 - 2e-24 86.1 0.0 2.5e-11 43.1 0.0 3.6 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 GET2 PF08690.5 KPI42477.1 - 0.059 12.6 1.1 0.13 11.5 0.8 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 IBR PF01485.16 KPI42478.1 - 0.00022 21.0 12.6 0.00033 20.4 2.7 4.6 4 1 1 5 5 5 3 IBR domain Cytochrome_CBB3 PF13442.1 KPI42478.1 - 1.4 9.1 5.2 7.6 6.7 0.0 3.2 4 0 0 4 4 4 0 Cytochrome C oxidase, cbb3-type, subunit III PPR PF01535.15 KPI42479.1 - 5.7e-05 22.8 0.4 0.0083 16.0 0.0 3.2 3 0 0 3 3 3 1 PPR repeat PPR_2 PF13041.1 KPI42479.1 - 0.00041 20.2 0.0 0.12 12.3 0.0 2.9 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 KPI42479.1 - 0.00058 19.9 0.2 0.05 13.8 0.0 3.9 3 0 0 3 3 3 1 Pentatricopeptide repeat domain TPR_14 PF13428.1 KPI42479.1 - 1.6 9.5 5.2 2.6 8.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat IF-2B PF01008.12 KPI42480.1 - 1.7e-15 56.7 1.5 8.3e-11 41.3 0.1 2.2 2 0 0 2 2 2 2 Initiation factor 2 subunit family NUDIX PF00293.23 KPI42480.1 - 1.6e-06 27.8 0.0 2.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain GRAS PF03514.9 KPI42480.1 - 0.1 11.2 0.2 0.16 10.6 0.2 1.2 1 0 0 1 1 1 0 GRAS domain family SLY PF12485.3 KPI42480.1 - 2.7 8.2 7.3 2 8.6 1.6 2.3 1 1 1 2 2 2 0 Lymphocyte signaling adaptor protein Acetyltransf_1 PF00583.19 KPI42481.1 - 4.3e-10 39.4 0.0 6.4e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI42481.1 - 1.5e-06 28.3 0.0 2.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KPI42481.1 - 9.8e-05 22.0 0.0 0.00021 20.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KPI42481.1 - 0.052 13.3 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain YL1 PF05764.8 KPI42481.1 - 5.3 6.5 6.7 8.5 5.8 4.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF4202 PF13875.1 KPI42482.1 - 8e-77 257.0 0.4 9e-77 256.8 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) GFA PF04828.9 KPI42483.1 - 7.4e-13 48.2 0.0 1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Aldedh PF00171.17 KPI42484.1 - 1.3e-138 462.2 4.2 4.2e-138 460.5 2.9 1.7 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KPI42484.1 - 0.0015 17.7 0.0 0.013 14.7 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Bax1-I PF01027.15 KPI42485.1 - 4.6e-32 111.2 10.5 7e-32 110.6 7.3 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PQ-loop PF04193.9 KPI42486.1 - 3.9e-37 125.6 11.1 1.2e-18 66.3 3.0 2.6 2 0 0 2 2 2 2 PQ loop repeat Claudin_2 PF13903.1 KPI42486.1 - 0.0043 16.7 2.1 0.047 13.3 0.0 3.1 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Steroid_dh PF02544.11 KPI42486.1 - 0.097 12.4 4.2 0.87 9.3 0.4 2.5 2 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase MFS_1 PF07690.11 KPI42487.1 - 3.9e-27 94.8 37.3 3.9e-27 94.8 25.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_18 PF00704.23 KPI42488.1 - 2.8e-14 53.3 0.0 5.9e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 zf-MYND PF01753.13 KPI42489.1 - 4.9e-08 32.7 12.9 1e-07 31.6 8.9 1.6 1 0 0 1 1 1 1 MYND finger SET PF00856.23 KPI42489.1 - 5.4e-06 26.8 0.0 2.1e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 SET domain Swi5 PF07061.6 KPI42490.1 - 6.1e-11 41.9 0.4 3.5e-10 39.5 0.0 2.3 3 0 0 3 3 3 1 Swi5 Adaptin_N PF01602.15 KPI42492.1 - 1.8e-132 442.3 10.1 2.3e-132 442.0 7.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KPI42492.1 - 8.5e-18 64.8 2.2 8.1e-17 61.6 0.1 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KPI42492.1 - 1.1e-14 54.4 4.6 4.9e-09 36.3 0.0 4.9 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 KPI42492.1 - 1.7e-10 40.0 1.8 0.0023 17.8 0.0 5.5 6 0 0 6 6 6 3 HEAT repeat Arm PF00514.18 KPI42492.1 - 1.1e-06 28.2 1.1 0.67 9.8 0.0 5.4 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KPI42492.1 - 8.8e-06 26.0 5.1 0.023 15.1 0.0 5.7 5 1 1 6 6 6 1 HEAT-like repeat FANCI_S2 PF14676.1 KPI42492.1 - 0.00028 20.8 1.1 1.4 8.8 0.0 3.3 3 1 1 4 4 4 2 FANCI solenoid 2 Atx10homo_assoc PF09759.4 KPI42492.1 - 0.00042 20.0 0.0 1.4 8.7 0.0 3.8 4 0 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 KPI42492.1 - 0.0011 18.3 3.1 1.1 8.5 0.0 3.5 3 1 0 3 3 3 2 CLASP N terminal Proteasom_PSMB PF10508.4 KPI42492.1 - 0.0061 14.8 0.8 0.026 12.8 0.0 2.3 2 2 1 3 3 3 1 Proteasome non-ATPase 26S subunit Epimerase PF01370.16 KPI42493.1 - 7.3e-12 45.2 0.0 2.5e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KPI42493.1 - 2.5e-07 31.0 0.0 4.2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KPI42493.1 - 1.9e-05 24.0 0.0 2.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KPI42493.1 - 0.0034 16.3 0.0 0.0072 15.2 0.0 1.7 2 1 0 2 2 2 1 Male sterility protein DXP_reductoisom PF02670.11 KPI42493.1 - 0.012 16.1 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase GFO_IDH_MocA PF01408.17 KPI42493.1 - 0.036 14.5 0.0 0.072 13.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 KPI42493.1 - 0.043 12.8 0.0 0.075 11.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase TPK_catalytic PF04263.11 KPI42493.1 - 0.11 12.1 0.0 0.58 9.7 0.0 2.0 2 0 0 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain Syntaxin-18_N PF10496.4 KPI42494.1 - 1.6e-12 47.0 0.8 3.6e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 KPI42494.1 - 9.2e-05 22.0 6.9 0.00011 21.8 1.3 2.8 3 0 0 3 3 3 1 SNARE domain DUF948 PF06103.6 KPI42494.1 - 0.024 14.5 8.0 1.3 8.9 0.9 3.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DDE_Tnp_ISAZ013 PF07592.6 KPI42494.1 - 0.058 12.1 0.5 0.12 11.0 0.3 1.5 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Fes1 PF08609.5 KPI42494.1 - 1.4 9.4 4.7 0.95 9.9 0.2 2.6 3 0 0 3 3 3 0 Nucleotide exchange factor Fes1 NOT2_3_5 PF04153.13 KPI42496.1 - 6.5e-27 94.0 0.1 1.2e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family adh_short PF00106.20 KPI42497.1 - 3e-05 23.9 0.1 0.0002 21.3 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI42497.1 - 0.028 14.0 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 KR domain MFS_1 PF07690.11 KPI42500.1 - 4.7e-35 120.9 34.2 5.5e-35 120.7 23.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FlaC_arch PF05377.6 KPI42501.1 - 0.31 10.9 1.8 0.8 9.6 1.2 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) BPL_N PF09825.4 KPI42502.1 - 1.7e-132 441.6 4.6 2.6e-130 434.5 3.2 2.4 1 1 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 KPI42502.1 - 5.3e-21 74.9 0.0 1.2e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 KPI42502.1 - 0.015 14.9 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain SAP PF02037.22 KPI42503.1 - 2.2e-05 23.8 0.1 3.5e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 SAP domain Cg6151-P PF10233.4 KPI42504.1 - 0.062 13.2 0.3 7.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein CG6151-P DUF4131 PF13567.1 KPI42504.1 - 0.42 9.9 3.0 0.67 9.3 1.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF4345 PF14248.1 KPI42504.1 - 1.9 7.9 7.4 0.58 9.6 2.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4345) Rer1 PF03248.8 KPI42505.1 - 3.9e-76 254.5 2.1 5.6e-76 254.0 1.5 1.2 1 0 0 1 1 1 1 Rer1 family Asp_protease PF09668.5 KPI42505.1 - 7.1e-52 174.1 0.1 1.2e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KPI42505.1 - 6.4e-10 39.4 0.0 1.3e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 KPI42505.1 - 1.5e-08 33.9 0.0 2.7e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.1 KPI42505.1 - 1e-07 31.6 0.0 2.4e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KPI42505.1 - 2e-06 27.7 0.0 3.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 KPI42505.1 - 1.6e-05 24.7 0.0 5.1e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease UBA PF00627.26 KPI42505.1 - 0.0061 16.3 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 KPI42505.1 - 0.033 13.7 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain DUF2360 PF10152.4 KPI42505.1 - 0.4 10.9 10.9 1 9.6 1.4 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF2423 PF10338.4 KPI42506.1 - 3.3e-14 52.5 5.2 3.3e-14 52.5 3.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Ribosomal_S9 PF00380.14 KPI42507.1 - 1.4e-34 118.9 0.3 2.3e-34 118.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HET PF06985.6 KPI42508.1 - 8.7e-21 74.5 0.0 2e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) VHL PF01847.11 KPI42508.1 - 0.068 12.7 0.0 8.5 5.9 0.0 2.6 3 0 0 3 3 3 0 von Hippel-Lindau disease tumour suppressor protein RibD_C PF01872.12 KPI42509.1 - 2.8e-29 102.1 0.0 7.3e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 RibD C-terminal domain adh_short PF00106.20 KPI42510.1 - 5.6e-21 75.1 0.8 8.3e-21 74.6 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI42510.1 - 4.9e-09 36.0 0.4 7.8e-09 35.4 0.3 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI42510.1 - 1.5e-06 28.1 0.0 2.1e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KPI42510.1 - 0.00028 20.5 0.1 0.0042 16.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KPI42510.1 - 0.00065 19.1 0.1 0.0018 17.7 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI42510.1 - 0.0022 18.0 0.2 0.0044 17.0 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 KPI42510.1 - 0.029 14.4 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KPI42510.1 - 0.032 14.4 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.10 KPI42510.1 - 0.062 12.1 0.0 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PB1 PF00564.19 KPI42511.1 - 0.00011 21.8 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 PB1 domain Ubiquitin_2 PF14560.1 KPI42511.1 - 0.03 14.5 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain 4HBT PF03061.17 KPI42513.1 - 0.12 12.5 0.2 2 8.6 0.0 2.4 2 1 0 2 2 2 0 Thioesterase superfamily Pep3_Vps18 PF05131.9 KPI42514.1 - 3.4e-47 159.5 0.0 2.3e-46 156.8 0.0 2.4 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KPI42514.1 - 6.8e-10 38.7 11.5 5.3e-07 29.3 0.2 3.7 3 1 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.4 KPI42514.1 - 0.00024 21.2 0.2 0.00073 19.6 0.1 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 KPI42514.1 - 0.0011 18.7 3.3 0.0029 17.3 2.3 1.8 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KPI42514.1 - 0.0027 17.4 0.5 0.0065 16.1 0.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Syntaxin-6_N PF09177.6 KPI42514.1 - 0.025 14.9 1.9 0.23 11.8 0.1 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal PspA_IM30 PF04012.7 KPI42514.1 - 0.025 13.9 2.5 0.05 12.9 0.3 2.2 2 0 0 2 2 2 0 PspA/IM30 family DUF1664 PF07889.7 KPI42514.1 - 0.027 14.2 1.9 0.049 13.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-C3HC4 PF00097.20 KPI42514.1 - 0.033 13.8 0.4 0.077 12.6 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_19 PF14559.1 KPI42514.1 - 0.066 13.5 4.4 3.3 8.1 1.9 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat DNA_pol3_theta PF06440.6 KPI42514.1 - 0.073 12.6 0.2 0.3 10.6 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III, theta subunit zf-C3HC4_2 PF13923.1 KPI42514.1 - 0.094 12.7 0.7 0.25 11.3 0.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.4 KPI42514.1 - 0.17 11.9 0.0 0.17 11.9 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) RAI1 PF08652.6 KPI42515.1 - 2.7e-26 91.1 0.0 6.8e-26 89.8 0.0 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease ATP-synt_C PF00137.16 KPI42517.1 - 1.6e-23 82.3 30.1 7.8e-14 51.3 6.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Sugar_tr PF00083.19 KPI42518.1 - 3.4e-49 167.6 7.6 1.9e-29 102.5 1.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI42518.1 - 2.2e-20 72.7 15.6 9.7e-14 50.8 0.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI42518.1 - 0.00014 20.3 10.7 0.0082 14.5 0.2 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 KPI42518.1 - 0.013 13.7 6.7 0.046 11.9 0.0 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KPI42520.1 - 1.7e-74 251.0 20.8 2e-74 250.7 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI42520.1 - 3.1e-12 45.8 32.9 5.6e-08 31.8 13.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4188 PF13826.1 KPI42521.1 - 6e-27 94.0 0.0 9e-27 93.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dabb PF07876.7 KPI42521.1 - 0.073 13.5 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain DUF3291 PF11695.3 KPI42521.1 - 0.083 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) CMD PF02627.15 KPI42522.1 - 9e-22 76.7 0.2 1.3e-21 76.2 0.2 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Fe-ADH PF00465.14 KPI42522.1 - 0.088 11.4 0.0 0.092 11.3 0.0 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase AMP-binding PF00501.23 KPI42523.1 - 5e-92 308.4 0.0 5.9e-92 308.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI42523.1 - 3.9e-14 53.3 0.0 1.2e-13 51.7 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.19 KPI42525.1 - 1.8e-41 142.1 17.3 3.7e-41 141.1 12.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI42525.1 - 1.5e-18 66.6 27.6 1.5e-18 66.6 19.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KPI42528.1 - 4e-07 29.4 0.0 2.7e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain SnoaL_4 PF13577.1 KPI42529.1 - 1.8e-07 31.0 0.3 2.9e-07 30.4 0.2 1.3 1 0 0 1 1 1 1 SnoaL-like domain Helicase_C PF00271.26 KPI42530.1 - 1.1e-13 50.7 0.0 3.4e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KPI42530.1 - 5.5e-08 32.6 0.0 1.3e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KPI42530.1 - 8.8e-07 28.5 0.4 0.009 15.5 0.0 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 KPI42530.1 - 0.00034 20.4 0.2 0.47 10.2 0.0 3.3 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KPI42530.1 - 0.0081 16.3 1.7 0.033 14.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain HA2 PF04408.18 KPI42530.1 - 0.028 14.4 7.3 0.056 13.4 0.0 3.2 2 2 0 3 3 3 0 Helicase associated domain (HA2) AAA_19 PF13245.1 KPI42530.1 - 0.068 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 KPI42530.1 - 0.14 11.2 1.5 0.41 9.7 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.1 KPI42530.1 - 0.41 10.9 0.0 0.41 10.9 0.0 3.6 5 0 0 5 5 5 0 AAA domain Abhydrolase_2 PF02230.11 KPI42531.1 - 7e-56 189.0 0.0 8.4e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KPI42531.1 - 3e-10 40.0 0.0 6.3e-10 38.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI42531.1 - 1.8e-06 28.0 0.1 0.0012 18.7 0.0 2.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI42531.1 - 2.6e-05 23.5 0.9 0.00055 19.2 0.1 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.8 KPI42531.1 - 6.7e-05 22.4 0.0 0.00055 19.4 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 KPI42531.1 - 0.00035 20.1 0.0 0.0068 15.9 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 KPI42531.1 - 0.0011 18.5 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydro_lipase PF04083.11 KPI42531.1 - 0.031 13.6 0.0 0.39 10.1 0.0 2.1 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DLH PF01738.13 KPI42531.1 - 0.047 12.9 0.1 0.074 12.3 0.0 1.3 1 1 0 1 1 1 0 Dienelactone hydrolase family Cutinase PF01083.17 KPI42531.1 - 0.05 13.3 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase LIP PF03583.9 KPI42531.1 - 0.15 11.2 0.1 1.1 8.3 0.0 2.1 1 1 0 2 2 2 0 Secretory lipase Ku PF02735.11 KPI42532.1 - 1.2e-36 125.9 0.0 8e-36 123.3 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KPI42532.1 - 6.2e-35 120.6 0.0 1.3e-34 119.6 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 KPI42532.1 - 7.5e-15 55.2 0.0 2.1e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 KPI42532.1 - 1.6e-13 49.8 0.0 3e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 KPI42532.1 - 0.0095 15.4 0.0 0.024 14.1 0.0 1.7 1 1 0 1 1 1 1 HeH/LEM domain MARVEL PF01284.18 KPI42533.1 - 6.9e-07 29.1 5.0 9.3e-07 28.7 3.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Choline_transpo PF04515.7 KPI42533.1 - 0.013 14.3 1.4 0.019 13.7 1.0 1.3 1 1 0 1 1 1 0 Plasma-membrane choline transporter Polysacc_synt_3 PF13440.1 KPI42533.1 - 0.013 14.9 6.2 0.11 11.8 1.3 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF1720 PF08226.6 KPI42533.1 - 0.057 13.4 3.6 0.16 12.0 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1720) DUF2456 PF10445.4 KPI42533.1 - 0.4 10.6 3.1 2.2 8.2 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2456) BTB PF00651.26 KPI42534.1 - 3.1e-10 40.0 0.1 8e-09 35.4 0.0 2.5 2 1 1 3 3 3 1 BTB/POZ domain DUF2461 PF09365.5 KPI42535.1 - 8.4e-72 241.0 0.0 1.1e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) CDC45 PF02724.9 KPI42535.1 - 0.25 9.3 2.7 0.32 8.9 1.9 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM110_C PF14160.1 KPI42535.1 - 1.6 9.7 5.1 3.3 8.6 3.5 1.5 1 0 0 1 1 1 0 Centrosome-associated C terminus Nop14 PF04147.7 KPI42535.1 - 5 4.9 8.7 6.7 4.4 6.0 1.1 1 0 0 1 1 1 0 Nop14-like family Reo_sigmaC PF04582.7 KPI42536.1 - 0.0064 15.7 2.4 0.0064 15.7 1.6 2.1 3 0 0 3 3 3 1 Reovirus sigma C capsid protein Phage_terminase PF10668.4 KPI42537.1 - 0.021 14.6 0.4 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Phage terminase small subunit SnoaL PF07366.7 KPI42538.1 - 1.1e-22 79.9 0.0 1.3e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KPI42538.1 - 4.3e-10 39.9 0.0 5.3e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Ral PF11058.3 KPI42538.1 - 0.091 12.1 0.1 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral CFEM PF05730.6 KPI42539.1 - 1.3e-08 34.5 9.8 2.7e-08 33.4 6.8 1.6 1 0 0 1 1 1 1 CFEM domain Tyrosinase PF00264.15 KPI42540.1 - 9.1e-22 78.3 0.0 1.6e-21 77.5 0.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Amidohydro_2 PF04909.9 KPI42541.1 - 1.2e-31 110.3 0.0 1.7e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase DUF2205 PF10224.4 KPI42542.1 - 0.0017 17.9 0.3 0.0031 17.0 0.2 1.3 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) CGI-121 PF08617.5 KPI42543.1 - 2.2e-51 173.7 0.1 2.5e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 CUE PF02845.11 KPI42543.1 - 0.15 11.6 0.5 1.5 8.3 0.0 2.8 4 0 0 4 4 4 0 CUE domain GPI-anchored PF10342.4 KPI42544.1 - 2.7e-07 30.9 2.7 5e-07 30.1 0.1 2.7 4 0 0 4 4 4 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SKG6 PF08693.5 KPI42544.1 - 0.00066 18.9 0.2 0.0014 17.8 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KPI42544.1 - 0.017 14.6 0.0 0.096 12.1 0.0 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF4448) TMEM240 PF15207.1 KPI42544.1 - 0.036 13.6 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 TMEM240 family Mid2 PF04478.7 KPI42544.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Methyltransf_2 PF00891.13 KPI42545.1 - 1.6e-27 96.2 0.0 2.6e-27 95.5 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KPI42545.1 - 0.0019 18.7 0.0 0.0049 17.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI42545.1 - 0.072 12.6 0.0 0.17 11.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Striatin PF08232.7 KPI42546.1 - 0.0011 19.2 1.3 0.0051 17.1 0.0 2.3 2 0 0 2 2 2 1 Striatin family BBP1_C PF15272.1 KPI42546.1 - 0.1 12.1 0.9 0.19 11.2 0.7 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal CCDC-167 PF15188.1 KPI42546.1 - 0.51 10.3 2.0 0.62 10.0 0.4 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 adh_short PF00106.20 KPI42547.1 - 9.6e-06 25.6 0.0 1.6e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase p450 PF00067.17 KPI42548.1 - 7.4e-59 199.4 0.0 3.6e-50 170.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Got1 PF04178.7 KPI42550.1 - 1.5e-18 66.9 14.6 1.8e-18 66.7 10.1 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 KPI42550.1 - 0.16 11.6 7.9 0.043 13.4 2.6 2.1 2 0 0 2 2 2 0 YrhK-like protein DUF4418 PF14387.1 KPI42550.1 - 0.31 10.8 2.8 0.76 9.5 1.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4418) Slx4 PF09494.5 KPI42551.1 - 1.9e-24 85.1 0.3 3.3e-24 84.3 0.2 1.4 1 0 0 1 1 1 1 Slx4 endonuclease PhyH PF05721.8 KPI42552.1 - 2.6e-06 27.6 0.1 1.2e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DHO_dh PF01180.16 KPI42553.1 - 7.4e-16 57.9 0.0 1.1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.10 KPI42553.1 - 1.4 7.9 4.6 2.3 7.2 3.2 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase F-box-like PF12937.2 KPI42554.1 - 1.4e-05 24.7 0.2 4.2e-05 23.1 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KPI42554.1 - 0.00036 20.0 0.0 0.0017 17.9 0.0 2.1 2 0 0 2 2 2 1 F-box domain Herpes_BLLF1 PF05109.8 KPI42554.1 - 2.3 6.0 12.5 3.5 5.4 8.6 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) p450 PF00067.17 KPI42555.1 - 1.3e-60 205.3 0.0 1.9e-60 204.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MbeB_N PF04837.7 KPI42555.1 - 0.2 11.7 0.1 5.3 7.2 0.0 2.3 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Fungal_trans PF04082.13 KPI42556.1 - 0.00064 18.6 0.7 0.001 17.9 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GRAM PF02893.15 KPI42557.1 - 2.1e-16 59.1 0.0 4.4e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 GRAM domain CAP PF00188.21 KPI42558.1 - 0.00061 20.2 9.3 0.0046 17.4 0.8 3.2 2 2 0 2 2 2 2 Cysteine-rich secretory protein family Hydrolase_6 PF13344.1 KPI42559.1 - 9.4e-27 92.8 0.0 1.6e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KPI42559.1 - 0.018 15.4 0.0 0.032 14.6 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glyco_tranf_2_4 PF13704.1 KPI42559.1 - 0.025 14.9 0.0 0.084 13.2 0.0 1.8 1 1 1 2 2 2 0 Glycosyl transferase family 2 DUF3874 PF12990.2 KPI42560.1 - 0.082 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) ECH PF00378.15 KPI42562.1 - 2.5e-56 190.5 1.3 3e-56 190.2 0.9 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KPI42562.1 - 0.057 13.1 0.2 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 ECH_C PF13766.1 KPI42562.1 - 0.067 13.3 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Ribosomal_L28e PF01778.12 KPI42563.1 - 3.6e-36 124.1 3.8 4.5e-36 123.8 2.6 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family MBF1 PF08523.5 KPI42563.1 - 0.39 10.7 4.3 0.11 12.5 0.5 2.0 2 0 0 2 2 2 0 Multiprotein bridging factor 1 Pyr_redox_3 PF13738.1 KPI42564.1 - 6.5e-15 55.7 0.0 7.4e-14 52.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI42564.1 - 9.9e-07 28.8 0.0 0.36 10.6 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI42564.1 - 0.00028 19.2 0.0 0.042 12.0 0.0 2.5 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI42564.1 - 0.004 17.1 2.2 0.037 14.0 0.8 2.9 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KPI42564.1 - 0.0043 16.8 1.3 0.43 10.3 0.2 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KPI42564.1 - 0.12 11.2 0.0 0.47 9.3 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 KPI42565.1 - 2.4e-10 40.0 2.4 2.3e-05 23.6 0.1 2.7 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 KPI42565.1 - 0.0021 17.0 0.2 0.19 10.6 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KPI42565.1 - 0.0038 17.5 0.3 0.01 16.2 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI42565.1 - 0.06 13.2 0.5 0.38 10.6 0.3 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KPI42565.1 - 0.082 11.7 0.0 0.17 10.6 0.0 1.5 1 0 0 1 1 1 0 Squalene epoxidase Asp PF00026.18 KPI42566.1 - 7e-46 156.9 0.9 2.8e-44 151.6 0.6 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KPI42566.1 - 3e-05 24.0 1.7 0.00027 20.9 0.4 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KPI42566.1 - 0.0031 17.0 0.0 0.073 12.6 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KPI42566.1 - 0.011 16.2 0.2 0.79 10.2 0.0 2.9 2 1 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.1 KPI42566.1 - 0.03 14.1 0.1 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DSPc PF00782.15 KPI42567.1 - 1.5e-07 31.0 0.0 0.0095 15.5 0.0 2.8 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain DUF1295 PF06966.7 KPI42568.1 - 8e-06 25.3 0.0 1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KPI42568.1 - 0.059 13.4 0.1 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Phospholipid methyltransferase Antig_Caf1 PF09255.5 KPI42568.1 - 0.089 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Caf1 Capsule antigen Ion_trans PF00520.26 KPI42569.1 - 2.3e-102 340.4 77.3 3.9e-33 114.4 6.8 4.5 4 0 0 4 4 4 4 Ion transport protein Y_phosphatase3 PF13350.1 KPI42570.1 - 2.6e-29 102.5 0.1 7.4e-14 52.3 0.0 3.5 3 0 0 3 3 3 2 Tyrosine phosphatase family DLIC PF05783.6 KPI42570.1 - 5e-26 91.4 10.9 2.7e-18 65.9 0.0 4.1 3 1 1 4 4 4 2 Dynein light intermediate chain (DLIC) Y_phosphatase3C PF13348.1 KPI42570.1 - 4.9e-08 32.9 0.0 2e-07 30.9 0.0 2.2 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Utp12 PF04003.7 KPI42570.1 - 0.037 13.9 0.2 0.14 12.0 0.1 2.0 2 0 0 2 2 2 0 Dip2/Utp12 Family CNH PF00780.17 KPI42571.1 - 6.7e-73 245.4 0.0 3.7e-72 243.0 0.0 2.0 2 0 0 2 2 2 1 CNH domain RhoGEF PF00621.15 KPI42571.1 - 4.6e-38 130.8 0.0 8.2e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 KPI42571.1 - 4.3e-37 127.0 0.0 9.9e-37 125.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.16 KPI42571.1 - 6.6e-13 48.2 0.1 1.7e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_2 PF13180.1 KPI42572.1 - 1.7e-06 27.7 0.0 3.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KPI42572.1 - 9.1e-05 22.5 0.0 0.00021 21.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 KPI42572.1 - 0.00023 21.1 0.1 0.002 18.1 0.1 2.1 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain MAGE_N PF12440.3 KPI42572.1 - 0.041 14.1 0.6 0.076 13.2 0.4 1.4 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal NRDE PF05742.7 KPI42573.1 - 6.3e-40 137.1 0.0 1.3e-39 136.2 0.0 1.4 1 1 0 1 1 1 1 NRDE protein Pkinase PF00069.20 KPI42574.1 - 1.6e-17 63.5 0.1 1.7e-12 47.0 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KPI42574.1 - 1.8e-06 27.2 0.0 1.7e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Metallophos PF00149.23 KPI42575.1 - 9.1e-39 132.9 0.1 1.3e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 KPI42575.1 - 2.6e-27 94.6 1.1 6.8e-27 93.3 0.8 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 KPI42575.1 - 3.5e-12 45.7 3.7 6.9e-11 41.6 1.1 2.6 1 1 1 2 2 2 1 TPR repeat TPR_1 PF00515.23 KPI42575.1 - 0.00024 20.5 1.3 0.0046 16.5 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KPI42575.1 - 0.0018 18.0 1.7 0.039 13.8 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KPI42575.1 - 0.0021 18.5 2.0 2 9.2 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KPI42575.1 - 0.0085 16.7 2.2 4.9 7.9 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KPI42575.1 - 0.011 15.8 1.4 3.6 8.0 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Urm1 PF09138.6 KPI42577.1 - 3.1e-32 110.5 0.0 9.1e-32 109.0 0.0 1.6 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KPI42577.1 - 0.00019 21.7 0.0 0.00031 21.0 0.0 1.3 1 0 0 1 1 1 1 ThiS family ADH_N PF08240.7 KPI42578.1 - 1.8e-07 30.8 0.3 7.5e-07 28.8 0.1 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_20 PF00728.17 KPI42579.1 - 4.4e-37 128.0 1.2 5.1e-36 124.5 0.8 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 KPI42579.1 - 4.4e-07 30.4 0.0 8.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 GCD14 PF08704.5 KPI42580.1 - 3.8e-58 196.9 0.6 1.1e-57 195.3 0.0 2.1 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 KPI42580.1 - 0.0028 17.6 0.0 0.0057 16.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain DUF2167 PF09935.4 KPI42580.1 - 0.0037 16.1 0.5 0.0064 15.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2167) FAD_binding_3 PF01494.14 KPI42581.1 - 1.3e-73 248.1 0.0 1.8e-73 247.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Polysacc_deac_1 PF01522.16 KPI42582.1 - 2.1e-24 85.5 0.0 3.6e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 KPI42582.1 - 1.2e-05 24.8 0.2 1.9e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.10 KPI42582.1 - 2.7e-05 23.2 0.2 3.6e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2194 PF09960.4 KPI42582.1 - 0.082 10.9 0.0 0.11 10.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) CDP-OH_P_transf PF01066.16 KPI42584.1 - 2.4e-15 56.6 6.2 2.4e-15 56.6 4.3 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase YwiC PF14256.1 KPI42584.1 - 0.0011 19.0 2.4 0.0011 19.0 1.7 3.3 3 1 1 4 4 4 1 YwiC-like protein Response_reg PF00072.19 KPI42585.1 - 1.2e-18 67.0 0.0 2.2e-13 50.1 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain cwf21 PF08312.7 KPI42586.1 - 2.4e-11 43.3 20.9 2.4e-11 43.3 14.5 2.3 2 1 0 2 2 2 1 cwf21 domain Ferrochelatase PF00762.14 KPI42587.1 - 3.8e-92 308.6 0.0 4.3e-92 308.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase RRM_1 PF00076.17 KPI42588.1 - 6e-22 77.0 0.6 4.6e-12 45.3 0.1 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI42588.1 - 6.3e-16 58.1 0.0 7.8e-09 35.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI42588.1 - 0.00089 19.0 0.0 0.0028 17.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FXR1P_C PF12235.3 KPI42588.1 - 0.28 11.2 9.1 0.11 12.5 3.8 2.1 2 0 0 2 2 2 0 Fragile X-related 1 protein C terminal RRM_1 PF00076.17 KPI42589.1 - 5.9e-08 32.2 0.0 1.3e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI42589.1 - 3.7e-07 29.8 0.0 9.8e-07 28.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI42589.1 - 1.4e-05 24.9 0.3 2.9e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KPI42589.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 KPI42589.1 - 0.063 12.9 1.7 0.11 12.2 1.2 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cu_amine_oxid PF01179.15 KPI42590.1 - 1.7e-156 521.1 0.0 2.1e-156 520.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KPI42590.1 - 2.3e-19 69.3 0.0 4.1e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KPI42590.1 - 3.9e-12 46.0 0.0 7.2e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Ferritin_2 PF13668.1 KPI42592.1 - 1.7e-37 128.3 0.5 2.6e-37 127.8 0.3 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF455 PF04305.9 KPI42592.1 - 0.086 12.0 0.1 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF455) Lamp PF01299.12 KPI42592.1 - 3.5 6.6 5.7 1.4 7.9 2.1 1.6 1 1 1 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) tRNA-synt_2b PF00587.20 KPI42593.1 - 1.3e-68 229.9 0.1 2.6e-68 228.9 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KPI42593.1 - 1.4e-20 73.0 0.0 1.4e-20 73.0 0.0 3.2 4 0 0 4 4 4 1 Anticodon binding domain Aminotran_1_2 PF00155.16 KPI42594.1 - 6.9e-80 268.7 0.0 7.8e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Hist_deacetyl PF00850.14 KPI42595.1 - 4.4e-59 200.2 0.4 2e-43 148.8 0.0 2.3 2 0 0 2 2 2 2 Histone deacetylase domain SCA7 PF08313.7 KPI42595.1 - 1.4e-16 59.8 0.0 2.9e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 SCA7, zinc-binding domain Clr5 PF14420.1 KPI42595.1 - 3.7e-14 52.3 5.3 1.3e-13 50.6 3.5 2.1 2 0 0 2 2 2 1 Clr5 domain DUF2855 PF11017.3 KPI42595.1 - 0.16 11.0 0.7 0.31 10.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) F-box PF00646.28 KPI42596.1 - 1.5e-05 24.4 0.1 3.3e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.11 KPI42597.1 - 1.5e-17 63.3 34.6 4.3e-13 48.7 10.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2304 PF10066.4 KPI42597.1 - 0.0082 15.9 0.7 0.0082 15.9 0.5 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2304) ATG22 PF11700.3 KPI42597.1 - 0.22 9.9 11.6 0.45 8.9 8.0 1.4 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like PINIT PF14324.1 KPI42598.1 - 4.3e-25 88.4 1.2 1.3e-16 60.9 0.1 2.6 1 1 1 2 2 2 2 PINIT domain zf-MIZ PF02891.15 KPI42598.1 - 3.5e-22 77.6 6.0 5.9e-22 76.9 4.2 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 KPI42598.1 - 4.2e-08 32.4 0.1 8.8e-08 31.4 0.1 1.6 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 KPI42598.1 - 3.4e-05 23.2 2.1 6.6e-05 22.3 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit HU-DNA_bdg PF14848.1 KPI42598.1 - 0.063 12.9 0.1 0.18 11.4 0.1 1.8 1 0 0 1 1 1 0 DNA-binding domain zf-C3HC4_4 PF15227.1 KPI42598.1 - 0.67 9.8 4.9 1.1 9.1 3.4 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FAD_binding_3 PF01494.14 KPI42600.1 - 1e-19 70.8 2.1 3e-15 56.1 0.4 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KPI42600.1 - 3.7e-07 29.3 0.0 8.4e-05 21.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI42600.1 - 4.1e-06 26.7 0.1 1.7e-05 24.7 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KPI42600.1 - 1.4e-05 24.9 0.0 3.6e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KPI42600.1 - 0.00026 19.9 0.8 0.00068 18.5 0.5 1.7 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KPI42600.1 - 0.00057 19.8 0.0 0.0012 18.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KPI42600.1 - 0.0036 16.1 0.0 0.023 13.5 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.22 KPI42600.1 - 0.0073 16.6 0.2 0.018 15.3 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI42600.1 - 0.0097 14.4 0.1 0.015 13.8 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 KPI42600.1 - 0.028 13.3 1.2 0.36 9.6 0.4 2.5 2 1 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 KPI42600.1 - 0.031 12.9 0.7 1 7.9 0.2 2.7 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.12 KPI42600.1 - 0.041 12.9 0.1 0.076 12.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 KPI42600.1 - 0.056 12.3 0.2 0.085 11.7 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF4567 PF15131.1 KPI42600.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) DUF3201 PF11447.3 KPI42601.1 - 0.1 12.0 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) Sec23_trunk PF04811.10 KPI42602.1 - 3.3e-29 101.9 0.0 2.6e-26 92.4 0.0 2.2 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KPI42602.1 - 2.2e-24 84.8 0.0 4.2e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KPI42602.1 - 1.2e-17 64.2 0.0 2.2e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KPI42602.1 - 1.3e-07 31.0 2.8 2.5e-07 30.1 2.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KPI42602.1 - 2.8e-07 30.1 0.0 5.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat SLS PF14611.1 KPI42602.1 - 0.18 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Abhydrolase_3 PF07859.8 KPI42603.1 - 1.5e-44 152.0 0.2 2.5e-44 151.4 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI42603.1 - 0.00043 20.0 0.0 0.00067 19.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI42603.1 - 0.014 14.6 0.0 4 6.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.23 KPI42603.1 - 0.016 13.9 0.0 0.11 11.1 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family DLH PF01738.13 KPI42603.1 - 0.056 12.7 0.0 0.095 11.9 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Mannitol_dh_C PF08125.8 KPI42604.1 - 2.1e-48 164.6 0.0 2.9e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KPI42604.1 - 1.1e-18 67.6 0.4 7.5e-18 64.9 0.0 2.2 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.13 KPI42604.1 - 0.003 17.2 2.8 0.02 14.5 0.0 2.9 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KPI42604.1 - 0.019 14.7 1.9 0.068 12.8 0.3 2.5 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KPI42604.1 - 0.047 13.1 0.0 2.2 7.7 0.0 2.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF724 PF05266.9 KPI42604.1 - 0.11 12.0 0.2 0.11 12.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) UDPG_MGDP_dh_N PF03721.9 KPI42604.1 - 0.33 10.3 3.8 0.12 11.7 0.5 2.0 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Polysacc_deac_1 PF01522.16 KPI42605.1 - 3.5e-33 113.8 0.0 4.2e-32 110.3 0.0 2.4 3 0 0 3 3 3 1 Polysaccharide deacetylase adh_short PF00106.20 KPI42605.1 - 1.2e-27 96.8 0.2 2e-27 96.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI42605.1 - 7.9e-24 84.7 0.0 1.4e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI42605.1 - 2.7e-12 46.7 0.2 5.7e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 KR domain Spore_IV_A PF09547.5 KPI42605.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) FAD_binding_3 PF01494.14 KPI42606.1 - 8.7e-18 64.4 2.6 2.5e-16 59.6 1.8 2.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI42606.1 - 3.5e-08 32.7 0.1 0.00011 21.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KPI42606.1 - 1.4e-06 27.4 0.3 0.0065 15.4 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 KPI42606.1 - 4.4e-05 23.4 0.1 0.0001 22.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KPI42606.1 - 0.00035 20.9 0.7 0.027 14.8 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI42606.1 - 0.0024 17.0 0.1 0.0041 16.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KPI42606.1 - 0.0033 17.3 0.0 0.0077 16.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI42606.1 - 0.0042 17.1 0.3 0.027 14.5 0.2 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI42606.1 - 0.0059 15.5 0.2 0.01 14.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KPI42606.1 - 0.011 14.8 0.1 0.14 11.1 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase ACP_syn_III PF08545.5 KPI42606.1 - 0.02 14.5 0.1 0.12 12.0 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NAD_binding_9 PF13454.1 KPI42606.1 - 0.031 14.0 1.6 3.9 7.2 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KPI42606.1 - 0.031 14.2 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 KPI42606.1 - 0.043 13.3 0.5 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KPI42606.1 - 0.049 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KPI42606.1 - 0.052 12.9 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 KPI42606.1 - 0.15 10.5 0.3 1.1 7.5 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_1 PF00232.13 KPI42607.1 - 9.3e-62 208.6 2.3 6.6e-39 133.3 0.2 3.7 1 1 2 3 3 3 3 Glycosyl hydrolase family 1 Peptidase_M18 PF02127.10 KPI42609.1 - 6.4e-124 413.7 0.0 3.1e-123 411.4 0.0 2.0 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Pyr_redox_3 PF13738.1 KPI42610.1 - 1.1e-23 84.4 0.0 1.8e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI42610.1 - 2.7e-11 42.3 0.2 8.1e-11 40.7 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI42610.1 - 1.4e-09 37.8 0.0 5.3e-09 35.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI42610.1 - 4.6e-08 32.3 0.1 5.7e-05 22.1 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KPI42610.1 - 2.8e-06 26.4 0.0 2.1e-05 23.6 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KPI42610.1 - 4.5e-05 23.2 0.1 0.00021 21.1 0.0 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.12 KPI42610.1 - 0.00072 18.7 0.0 0.0058 15.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KPI42610.1 - 0.0017 18.2 0.0 0.019 14.8 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI42610.1 - 0.0057 15.6 0.1 0.014 14.3 0.0 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein SF3b1 PF08920.5 KPI42610.1 - 0.035 14.1 0.1 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 Splicing factor 3B subunit 1 Phage_F PF02305.12 KPI42610.1 - 0.062 11.8 0.2 0.097 11.1 0.2 1.2 1 0 0 1 1 1 0 Capsid protein (F protein) CUE PF02845.11 KPI42610.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 CUE domain Shikimate_DH PF01488.15 KPI42610.1 - 0.094 12.8 0.0 4.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KPI42610.1 - 0.099 11.7 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UCH_1 PF13423.1 KPI42611.1 - 2.2e-59 201.3 0.0 2e-58 198.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Beta-lactamase PF00144.19 KPI42611.1 - 5.5e-40 137.3 0.0 1.3e-39 136.1 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase UCH PF00443.24 KPI42611.1 - 3e-10 39.6 0.0 9.2e-10 38.0 0.0 1.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase GDI PF00996.13 KPI42612.1 - 3.7e-40 137.5 0.0 1e-39 136.1 0.0 1.6 1 1 0 1 1 1 1 GDP dissociation inhibitor MRP-S25 PF13741.1 KPI42615.1 - 3.4e-73 245.9 0.7 4.3e-73 245.5 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 F-box PF00646.28 KPI42616.1 - 0.13 11.9 0.1 0.33 10.6 0.0 1.7 2 0 0 2 2 2 0 F-box domain Ldh_1_C PF02866.13 KPI42617.1 - 1.1e-42 145.6 0.0 3.7e-42 144.0 0.0 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 KPI42617.1 - 3.3e-37 127.4 0.1 2.1e-36 124.8 0.1 2.1 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Peptidase_C48 PF02902.14 KPI42617.1 - 1.6e-19 70.4 0.0 3.4e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Pkinase PF00069.20 KPI42618.1 - 4.9e-56 189.7 0.0 8.1e-56 189.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI42618.1 - 3.4e-23 82.0 0.0 1.2e-22 80.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KPI42618.1 - 0.00042 20.1 0.0 0.0036 17.0 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KPI42618.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 KPI42618.1 - 0.027 13.4 0.6 0.15 11.0 0.4 1.9 1 1 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 KPI42618.1 - 0.23 10.2 0.0 0.38 9.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF1620 PF07774.8 KPI42619.1 - 3.4e-70 235.6 0.0 7.7e-70 234.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KPI42619.1 - 2.1e-15 56.8 17.6 7.4e-09 35.4 1.3 4.4 3 1 1 4 4 4 3 PQQ-like domain PQQ PF01011.16 KPI42619.1 - 4.2e-06 26.0 7.1 0.52 9.9 0.0 5.3 5 0 0 5 5 5 3 PQQ enzyme repeat PQQ_3 PF13570.1 KPI42619.1 - 1.1e-05 25.4 13.1 0.0035 17.5 0.2 6.2 6 1 1 7 7 7 3 PQQ-like domain EII-GUT PF03608.8 KPI42619.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 PTS system enzyme II sorbitol-specific factor Fungal_trans PF04082.13 KPI42620.1 - 5.2e-24 84.5 0.6 8e-24 83.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bot1p PF12298.3 KPI42621.1 - 5.1e-47 160.0 0.2 5.1e-47 160.0 0.1 1.8 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Vfa1 PF08432.5 KPI42621.1 - 2.2 8.2 5.2 0.75 9.7 0.5 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Es2 PF09751.4 KPI42624.1 - 8.5e-83 279.0 13.2 1e-82 278.7 9.2 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 DUF572 PF04502.8 KPI42624.1 - 1.3 8.1 6.6 0.13 11.4 1.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF1762 PF08574.5 KPI42626.1 - 1.5e-12 47.7 17.1 1.5e-12 47.7 11.8 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1762) Mito_fiss_reg PF05308.6 KPI42626.1 - 0.54 9.5 4.6 0.51 9.6 2.3 1.7 1 1 1 2 2 2 0 Mitochondrial fission regulator Glyco_tranf_2_3 PF13641.1 KPI42629.1 - 3.7e-18 66.1 0.1 3.7e-17 62.9 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KPI42629.1 - 7.1e-10 38.8 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KPI42629.1 - 3.1e-07 29.8 0.1 0.00021 20.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 TMEM51 PF15345.1 KPI42630.1 - 0.08 12.6 8.0 0.47 10.1 0.1 2.5 1 1 1 2 2 2 0 Transmembrane protein 51 Podoplanin PF05808.6 KPI42630.1 - 0.14 11.7 15.8 0.32 10.5 11.0 1.7 1 1 0 1 1 1 0 Podoplanin Macoilin PF09726.4 KPI42630.1 - 0.36 9.0 6.2 0.36 9.0 4.3 1.2 1 0 0 1 1 1 0 Transmembrane protein RRM_6 PF14259.1 KPI42631.1 - 1.5e-06 28.0 0.0 3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KPI42631.1 - 0.0009 18.8 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 6PF2K PF01591.13 KPI42632.1 - 1.7e-61 207.1 0.0 2.5e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KPI42632.1 - 7.3e-21 74.9 0.5 1.5e-20 73.9 0.3 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 KPI42632.1 - 6.2e-05 23.8 0.2 0.00026 21.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KPI42632.1 - 0.0012 18.7 0.1 0.035 13.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 KPI42632.1 - 0.057 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RabGAP-TBC PF00566.13 KPI42633.1 - 3.8e-46 157.2 1.1 5.5e-46 156.7 0.0 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 KPI42633.1 - 0.00046 19.8 0.8 0.082 12.8 0.1 3.8 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.1 KPI42633.1 - 0.0012 18.9 0.0 0.01 15.9 0.0 2.6 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KPI42633.1 - 0.011 14.9 0.1 0.16 11.3 0.3 2.9 3 0 0 3 3 3 0 EF hand NDUFA12 PF05071.11 KPI42634.1 - 1.6e-24 86.3 0.2 2e-24 86.0 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF2017 PF09438.5 KPI42635.1 - 0.38 10.2 2.6 0.56 9.7 0.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF2017) HAD_2 PF13419.1 KPI42636.1 - 6.2e-19 68.8 0.0 7.6e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KPI42636.1 - 1.7e-12 48.2 0.0 1e-10 42.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KPI42636.1 - 5.4e-08 32.4 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 KPI42636.1 - 1.5e-05 25.2 0.0 2.5e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KPI42636.1 - 0.016 15.0 0.1 0.52 10.2 0.0 2.8 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Transp_cyt_pur PF02133.10 KPI42637.1 - 2.3e-27 95.6 27.5 4.1e-27 94.8 19.1 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin OsmC PF02566.14 KPI42638.1 - 2.7e-16 59.6 0.0 4e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein DUF4560 PF15118.1 KPI42640.1 - 0.12 12.1 0.2 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4560) Mito_carr PF00153.22 KPI42641.1 - 9.6e-18 63.6 0.1 4.5e-12 45.5 0.0 3.6 3 1 0 3 3 3 2 Mitochondrial carrier protein Oxidored_FMN PF00724.15 KPI42642.1 - 9.4e-74 248.4 0.0 1.4e-67 228.1 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Gate PF07670.9 KPI42643.1 - 3.7 7.5 8.8 1.7 8.5 0.2 3.3 4 0 0 4 4 4 0 Nucleoside recognition SCIMP PF15050.1 KPI42645.1 - 0.014 15.3 0.1 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 SCIMP protein DPM3 PF08285.6 KPI42645.1 - 0.014 15.2 1.8 5 7.0 0.3 2.9 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) W_rich_C PF07483.6 KPI42645.1 - 0.028 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Tryptophan-rich Synechocystis species C-terminal domain EAP30 PF04157.11 KPI42646.1 - 5e-49 166.4 0.0 7e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KPI42646.1 - 2.2e-25 88.2 0.0 4.3e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Ribosomal_L50 PF10501.4 KPI42646.1 - 4.3e-06 26.6 0.2 9.9e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 Ribosomal subunit 39S zf-Sec23_Sec24 PF04810.10 KPI42646.1 - 0.00042 19.8 4.8 0.0049 16.4 0.4 2.6 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger DZR PF12773.2 KPI42646.1 - 0.0052 16.5 1.8 0.0072 16.1 0.3 1.9 2 0 0 2 2 2 1 Double zinc ribbon zf-RanBP PF00641.13 KPI42646.1 - 0.0055 15.7 6.5 0.011 14.8 0.6 2.5 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.1 KPI42646.1 - 0.17 11.1 0.6 0.41 9.9 0.4 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Rifin_STEVOR PF02009.11 KPI42647.1 - 0.0011 18.6 0.1 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family Herpes_gE PF02480.11 KPI42647.1 - 0.0016 16.7 0.0 0.0019 16.5 0.0 1.0 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E GAPT PF11770.3 KPI42647.1 - 0.0078 15.8 0.0 0.0085 15.7 0.0 1.1 1 0 0 1 1 1 1 GRB2-binding adapter (GAPT) Hum_adeno_E3A PF05393.6 KPI42647.1 - 0.035 13.7 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein IncA PF04156.9 KPI42647.1 - 0.064 12.8 0.1 0.091 12.3 0.1 1.3 1 1 0 1 1 1 0 IncA protein LRR19-TM PF15176.1 KPI42647.1 - 0.14 11.9 0.4 0.2 11.3 0.3 1.4 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain EMP70 PF02990.11 KPI42648.1 - 1.8e-140 468.9 0.4 7.3e-140 466.8 0.3 1.9 1 1 0 1 1 1 1 Endomembrane protein 70 Chitin_bind_1 PF00187.14 KPI42649.1 - 2.9e-05 23.9 35.1 0.016 15.1 6.9 2.9 2 2 0 2 2 2 2 Chitin recognition protein DUF4366 PF14283.1 KPI42649.1 - 0.05 13.0 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Hamartin PF04388.7 KPI42649.1 - 0.068 11.8 4.2 0.086 11.4 2.9 1.1 1 0 0 1 1 1 0 Hamartin protein Pol_alpha_B_N PF08418.5 KPI42650.1 - 4.1 6.8 6.8 1.5 8.3 0.4 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal HMG_box PF00505.14 KPI42651.1 - 2.2e-24 85.5 1.3 3.3e-24 84.9 0.9 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KPI42651.1 - 2.3e-19 69.5 1.6 4.2e-19 68.6 1.1 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KPI42651.1 - 0.00087 19.0 0.6 0.00087 19.0 0.4 2.1 2 1 0 2 2 2 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 KPI42651.1 - 0.063 13.4 2.0 0.082 13.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) CHDNT PF08073.7 KPI42651.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 CHDNT (NUC034) domain HET PF06985.6 KPI42652.1 - 1.6e-29 102.8 3.2 4.9e-29 101.2 0.3 2.6 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AAA_11 PF13086.1 KPI42653.1 - 1.1e-06 28.4 0.0 4.8e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KPI42653.1 - 0.022 14.1 0.0 0.059 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KPI42653.1 - 0.11 12.0 0.0 6.9 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain FolB PF02152.13 KPI42654.1 - 3.2e-14 53.0 0.0 1.1e-06 28.7 0.0 2.2 2 0 0 2 2 2 2 Dihydroneopterin aldolase HrpB4 PF09502.5 KPI42654.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) MFS_1 PF07690.11 KPI42655.1 - 2.3e-40 138.4 40.2 2.3e-40 138.4 27.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI42655.1 - 9.3e-09 34.3 11.5 9.3e-09 34.3 8.0 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter Clr5 PF14420.1 KPI42656.1 - 9.4e-14 51.0 2.5 1.4e-13 50.4 0.2 2.3 3 0 0 3 3 3 1 Clr5 domain DUF4248 PF14053.1 KPI42656.1 - 0.03 13.8 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) ubiquitin PF00240.18 KPI42657.1 - 1.9e-18 65.6 0.0 3.2e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KPI42657.1 - 5.6e-08 32.3 0.0 9.5e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 KPI42657.1 - 1.1e-06 28.2 0.0 4.5e-06 26.3 0.0 2.2 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD_2 PF13881.1 KPI42657.1 - 3.5e-06 26.8 0.0 6.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KPI42657.1 - 0.0034 17.5 0.0 0.0067 16.5 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 KPI42657.1 - 0.12 12.6 0.0 0.37 11.0 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain CRA PF06589.6 KPI42657.1 - 0.52 9.6 2.0 3.7 6.8 0.2 2.2 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Sugar_tr PF00083.19 KPI42658.1 - 3.4e-87 292.9 28.1 3.9e-87 292.7 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI42658.1 - 3.9e-19 68.5 36.2 5e-15 55.0 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Vma12 PF11712.3 KPI42658.1 - 3.4 7.3 4.7 0.8 9.4 0.1 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SLAC1 PF03595.12 KPI42659.1 - 8.8e-69 231.6 33.1 1.1e-68 231.3 23.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SBDS PF01172.13 KPI42660.1 - 1.1e-25 89.1 0.2 1.3e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DEAD PF00270.24 KPI42662.1 - 4.8e-27 94.5 0.4 4.4e-25 88.1 0.2 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI42662.1 - 2.1e-20 72.3 0.2 5.4e-20 71.0 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI42662.1 - 2.7e-07 30.5 0.5 6.1e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RNA_pol_N PF01194.12 KPI42663.1 - 8.5e-29 99.3 2.6 1e-28 99.0 1.8 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit COesterase PF00135.23 KPI42664.1 - 2.6e-57 194.7 0.0 4.1e-57 194.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF3425 PF11905.3 KPI42664.1 - 3.8e-17 62.4 0.2 8.1e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Abhydrolase_3 PF07859.8 KPI42664.1 - 2.8e-07 30.3 4.3 1.3e-06 28.1 0.8 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold bZIP_1 PF00170.16 KPI42664.1 - 0.00013 21.8 2.6 0.00013 21.8 1.8 2.0 2 0 0 2 2 2 1 bZIP transcription factor Esterase PF00756.15 KPI42664.1 - 0.0038 16.6 0.0 0.017 14.5 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KPI42664.1 - 0.024 14.4 0.1 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family bZIP_2 PF07716.10 KPI42664.1 - 0.081 12.7 4.0 0.17 11.7 2.8 1.5 1 0 0 1 1 1 0 Basic region leucine zipper CCDC144C PF14915.1 KPI42664.1 - 0.15 10.9 1.1 0.23 10.3 0.8 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Peptidase_M19 PF01244.16 KPI42665.1 - 4.7e-95 318.1 0.0 5.7e-95 317.9 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Cation_efflux PF01545.16 KPI42666.1 - 8.2e-34 116.9 3.3 1.1e-33 116.5 2.3 1.1 1 0 0 1 1 1 1 Cation efflux family MFS_1 PF07690.11 KPI42667.1 - 2.2e-38 131.8 40.0 4.8e-38 130.7 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI42667.1 - 3.3e-15 55.6 11.4 3.3e-15 55.6 7.9 2.6 2 2 0 2 2 2 1 Sugar (and other) transporter DUF1537 PF07005.6 KPI42668.1 - 7.7e-22 78.0 0.2 1.2e-21 77.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF1537 Glu_syn_central PF04898.9 KPI42668.1 - 0.0094 15.2 0.1 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain MFS_1 PF07690.11 KPI42669.1 - 2.1e-20 72.7 68.7 7.3e-15 54.5 25.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily CN_hydrolase PF00795.17 KPI42670.1 - 5.4e-22 78.0 0.0 7.7e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Aconitase PF00330.15 KPI42671.1 - 1.7e-180 600.4 0.1 2.1e-180 600.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KPI42671.1 - 3.2e-44 150.2 0.0 6.2e-44 149.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF2156 PF09924.4 KPI42672.1 - 9.6e-30 103.4 0.0 1.3e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) Pkinase PF00069.20 KPI42673.1 - 3.5e-38 131.2 0.0 1.1e-35 123.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain XPC-binding PF09280.6 KPI42673.1 - 3.8e-15 55.0 0.9 8.3e-15 53.9 0.6 1.6 1 0 0 1 1 1 1 XPC-binding domain Pkinase_Tyr PF07714.12 KPI42673.1 - 3e-12 46.1 0.0 9e-10 38.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_4 PF12763.2 KPI42673.1 - 4.8e-12 45.5 0.0 9.3e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 KPI42673.1 - 7.9e-07 28.7 0.0 1.9e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.1 KPI42673.1 - 0.00048 20.2 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.1 KPI42673.1 - 0.004 17.0 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 KPI42673.1 - 0.069 12.4 0.0 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 KPI42673.1 - 0.11 12.4 0.0 30 4.8 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain UBA_3 PF09288.5 KPI42673.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain CPSF_A PF03178.10 KPI42674.1 - 5e-98 328.1 0.0 3.9e-97 325.2 0.0 2.3 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 KPI42674.1 - 3e-60 203.8 0.0 5e-60 203.0 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF1945 PF09178.5 KPI42674.1 - 0.015 15.1 0.1 0.066 13.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1945) BBS2_N PF14781.1 KPI42674.1 - 0.027 14.1 0.2 25 4.4 0.0 3.8 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal WD40 PF00400.27 KPI42674.1 - 0.1 12.5 0.0 0.43 10.5 0.0 2.2 1 0 0 1 1 1 0 WD domain, G-beta repeat CoA_transf_3 PF02515.12 KPI42675.1 - 1.8e-61 206.7 0.0 2.4e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III DUF1932 PF09130.6 KPI42675.1 - 0.024 14.3 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) DLH PF01738.13 KPI42676.1 - 4.4e-14 52.2 2.0 4e-08 32.8 3.2 2.6 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KPI42676.1 - 0.0046 16.7 0.0 0.016 14.9 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family CAP_N PF01213.14 KPI42677.1 - 0.077 12.2 22.8 3.1 7.0 1.4 4.1 4 0 0 4 4 4 0 Adenylate cyclase associated (CAP) N terminal Caleosin PF05042.8 KPI42677.1 - 4 6.9 11.4 5.9 6.4 0.0 3.4 3 0 0 3 3 3 0 Caleosin related protein AMP-binding PF00501.23 KPI42678.1 - 8.8e-54 182.4 0.8 1.1e-22 80.0 0.0 4.6 3 1 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.6 KPI42678.1 - 1.6e-10 41.5 0.1 1.6e-10 41.5 0.1 3.2 3 0 0 3 3 3 1 DMAP1-binding Domain GvpG PF05120.7 KPI42678.1 - 0.06 13.1 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Gas vesicle protein G RNA_pol_I_TF PF04090.7 KPI42679.1 - 1.8e-13 50.2 0.0 4.5e-13 48.9 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor TPR_6 PF13174.1 KPI42679.1 - 0.26 11.8 4.2 3.2 8.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Tannase PF07519.6 KPI42681.1 - 4.4e-90 302.6 0.2 7.4e-66 222.7 0.0 2.1 1 1 1 2 2 2 2 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 KPI42681.1 - 0.00045 19.8 0.0 0.00083 18.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI42681.1 - 0.00084 19.1 0.0 0.094 12.4 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI42681.1 - 0.032 14.0 0.1 0.085 12.7 0.0 1.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family Mis12 PF05859.7 KPI42682.1 - 3.1e-41 140.5 0.7 4.4e-41 140.0 0.0 1.6 2 0 0 2 2 2 1 Mis12 protein DUF2309 PF10070.4 KPI42682.1 - 0.0055 14.8 1.9 0.2 9.7 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2309) DUF1843 PF08898.5 KPI42682.1 - 0.0074 16.3 1.5 0.0074 16.3 1.0 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF1843) M PF02370.11 KPI42682.1 - 3 8.5 6.9 23 5.7 1.0 3.7 3 0 0 3 3 3 0 M protein repeat COQ9 PF08511.6 KPI42683.1 - 3.3e-29 100.2 0.1 6.4e-29 99.2 0.0 1.5 1 0 0 1 1 1 1 COQ9 DUF2356 PF10189.4 KPI42684.1 - 0.014 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Conserved protein (DUF2356) Na_H_Exchanger PF00999.16 KPI42685.1 - 9.3e-29 100.1 18.4 1.5e-28 99.4 12.8 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 KPI42685.1 - 0.051 13.5 0.4 0.22 11.4 0.3 2.1 1 0 0 1 1 1 0 YrhC-like protein RTA1 PF04479.8 KPI42686.1 - 3.5e-18 65.9 1.9 3.5e-18 65.9 1.3 1.4 1 1 0 1 1 1 1 RTA1 like protein DUF308 PF03729.8 KPI42686.1 - 0.006 16.5 3.1 0.006 16.5 2.1 2.9 3 0 0 3 3 3 1 Short repeat of unknown function (DUF308) DUF4131 PF13567.1 KPI42686.1 - 4.2 6.7 11.8 1.3 8.4 1.6 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Fungal_trans_2 PF11951.3 KPI42687.1 - 7.1e-06 24.8 0.1 1.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF963 PF06131.6 KPI42687.1 - 0.022 14.0 1.6 0.048 12.9 1.1 1.5 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Fungal_trans PF04082.13 KPI42688.1 - 4.8e-19 68.2 1.7 1.2e-17 63.6 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 KPI42688.1 - 0.00041 19.0 0.2 0.00055 18.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_7 PF13499.1 KPI42689.1 - 0.00074 19.6 0.5 0.0023 18.0 0.3 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KPI42689.1 - 0.0013 17.8 0.3 0.0043 16.2 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KPI42689.1 - 0.0042 16.8 0.1 0.015 15.0 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 KPI42689.1 - 0.047 13.3 0.2 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair adh_short PF00106.20 KPI42690.1 - 2.3e-25 89.4 0.5 1.1e-24 87.2 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI42690.1 - 2e-20 73.6 0.0 2.6e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KPI42690.1 - 1.4e-06 27.9 0.0 8.8e-06 25.3 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI42690.1 - 2.2e-06 26.5 0.1 3e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KPI42690.1 - 3.1e-06 26.9 2.6 0.00018 21.2 1.8 3.0 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI42690.1 - 0.048 13.6 0.1 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_7 PF13241.1 KPI42690.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding F-box-like PF12937.2 KPI42691.1 - 1.4e-07 31.1 0.1 4.2e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KPI42691.1 - 0.00025 20.5 0.6 0.0037 16.8 0.0 2.5 2 0 0 2 2 2 1 F-box domain bZIP_2 PF07716.10 KPI42692.1 - 0.00058 19.6 7.4 0.00089 19.0 5.1 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KPI42692.1 - 0.0054 16.6 5.6 0.009 15.9 3.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor UDPG_MGDP_dh_N PF03721.9 KPI42693.1 - 3.7e-23 81.8 0.6 5.7e-23 81.2 0.4 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 KPI42693.1 - 1e-17 64.1 0.0 2.2e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain TrkA_N PF02254.13 KPI42693.1 - 7.1e-05 22.7 0.1 0.0032 17.4 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_2 PF03446.10 KPI42693.1 - 0.00013 21.8 0.2 0.00032 20.5 0.1 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.10 KPI42693.1 - 0.0018 18.4 0.0 0.0043 17.1 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 3HCDH_N PF02737.13 KPI42693.1 - 0.0088 15.7 0.1 0.025 14.2 0.0 1.8 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 KPI42693.1 - 0.023 15.2 0.0 0.18 12.3 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold CLAG PF03805.8 KPI42693.1 - 0.08 10.2 0.0 0.11 9.8 0.0 1.1 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein Form_Nir_trans PF01226.12 KPI42694.1 - 4.5e-74 248.4 17.7 5.1e-74 248.3 12.3 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF3341 PF11821.3 KPI42694.1 - 0.0038 16.7 0.1 0.0066 15.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3341) Abhydrolase_1 PF00561.15 KPI42696.1 - 4.7e-19 68.8 0.0 1.3e-15 57.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI42696.1 - 2.5e-18 66.7 0.0 4.2e-18 66.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI42696.1 - 1.1e-09 38.2 0.0 6e-09 35.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KPI42696.1 - 0.0045 16.4 0.0 0.14 11.5 0.0 2.2 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 KPI42696.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_4 PF08386.5 KPI42696.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Peptidase_S28 PF05577.7 KPI42696.1 - 0.13 10.8 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 BTB PF00651.26 KPI42697.1 - 3.2e-10 39.9 0.0 6.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-ribbon_3 PF13248.1 KPI42697.1 - 0.0059 15.7 0.1 0.016 14.4 0.1 1.7 1 0 0 1 1 1 1 zinc-ribbon domain Lar_restr_allev PF14354.1 KPI42697.1 - 0.0068 16.6 0.2 0.018 15.3 0.1 1.7 1 0 0 1 1 1 1 Restriction alleviation protein Lar DZR PF12773.2 KPI42697.1 - 0.019 14.7 0.3 0.038 13.7 0.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 KPI42697.1 - 0.061 12.8 0.6 0.15 11.5 0.4 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DUF2420 PF10336.4 KPI42697.1 - 0.077 12.5 0.1 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) DUF2039 PF10217.4 KPI42697.1 - 0.097 12.7 3.7 0.17 11.9 2.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) PAH PF02671.16 KPI42697.1 - 0.13 11.8 0.1 0.64 9.6 0.0 2.3 2 0 0 2 2 2 0 Paired amphipathic helix repeat Tropomyosin_1 PF12718.2 KPI42697.1 - 0.14 12.0 2.9 0.25 11.1 2.0 1.3 1 0 0 1 1 1 0 Tropomyosin like UPF0547 PF10571.4 KPI42697.1 - 0.15 11.7 3.2 0.19 11.4 0.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 UTP15_C PF09384.5 KPI42698.1 - 8.5e-41 139.0 0.0 1.4e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 KPI42698.1 - 5.3e-26 89.5 3.7 1.7e-08 33.9 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Glyco_transf_17 PF04724.8 KPI42700.1 - 1.7e-37 129.2 0.2 2.8e-37 128.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 17 Bystin PF05291.6 KPI42702.1 - 1.9e-119 398.1 0.0 2.6e-119 397.6 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF3237 PF11578.3 KPI42703.1 - 5.5e-31 106.8 0.0 8.4e-31 106.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) NAD_binding_6 PF08030.7 KPI42704.1 - 7.3e-23 81.1 0.0 1.2e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KPI42704.1 - 1.7e-22 79.2 0.0 3.3e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KPI42704.1 - 1.3e-17 64.0 8.2 1.3e-17 64.0 5.7 2.1 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KPI42704.1 - 2.2e-05 24.5 0.0 6.3e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain DPPIV_N PF00930.16 KPI42705.1 - 4.7e-102 341.1 4.0 6.3e-102 340.7 2.8 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KPI42705.1 - 2.1e-32 112.1 0.5 3.3e-32 111.4 0.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KPI42705.1 - 9.4e-05 22.2 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family ACC_central PF08326.7 KPI42705.1 - 0.22 9.6 0.0 0.32 9.0 0.0 1.1 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region DUF1180 PF06679.7 KPI42706.1 - 0.75 9.6 2.5 0.81 9.5 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) ADH_zinc_N PF00107.21 KPI42707.1 - 4e-22 78.1 0.1 1.2e-21 76.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI42707.1 - 1.5e-19 69.7 3.8 7.2e-18 64.3 2.7 2.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CPSase_L_chain PF00289.17 KPI42707.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Shikimate_DH PF01488.15 KPI42707.1 - 0.024 14.7 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KPI42707.1 - 0.026 13.5 0.1 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain ADH_zinc_N_2 PF13602.1 KPI42707.1 - 0.059 14.2 0.0 0.1 13.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KPI42707.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 KPI42707.1 - 0.28 11.0 1.5 0.96 9.2 1.1 1.8 1 1 0 1 1 1 0 ThiF family DASH_Duo1 PF08651.5 KPI42708.1 - 1.2e-25 88.8 0.6 2.1e-25 88.0 0.4 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 Tic20 PF09685.5 KPI42708.1 - 4e-05 23.5 1.4 6.1e-05 22.9 1.0 1.3 1 0 0 1 1 1 1 Tic20-like protein FUSC PF04632.7 KPI42708.1 - 7.5 4.8 10.0 12 4.1 6.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family POR PF01558.13 KPI42709.1 - 0.0068 16.3 0.0 0.87 9.4 0.0 2.5 1 1 1 2 2 2 2 Pyruvate ferredoxin/flavodoxin oxidoreductase Peptidase_S30 PF01577.11 KPI42709.1 - 3.2 7.0 6.7 4.6 6.5 1.8 2.1 2 0 0 2 2 2 0 Potyvirus P1 protease Bromodomain PF00439.20 KPI42710.1 - 4.6e-26 90.5 0.3 8.9e-26 89.6 0.2 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KPI42710.1 - 1.3e-09 38.0 0.1 2.4e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KPI42710.1 - 1.3e-08 34.7 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KPI42710.1 - 0.1 12.5 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_47 PF01532.15 KPI42711.1 - 2e-153 511.2 0.0 2.5e-153 510.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HSP70 PF00012.15 KPI42713.1 - 2.7e-12 45.4 0.5 5.5e-12 44.4 0.4 1.5 1 1 0 1 1 1 1 Hsp70 protein DUF3816 PF12822.2 KPI42714.1 - 0.51 10.2 11.4 0.19 11.6 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) Mad3_BUB1_I PF08311.7 KPI42716.1 - 2.5e-41 140.3 1.3 4.4e-41 139.5 0.9 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KPI42716.1 - 3e-11 42.9 0.0 1.7e-10 40.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI42716.1 - 1.4e-05 24.3 0.0 4.7e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.6 KPI42716.1 - 0.072 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 Seryl_tRNA_N PF02403.17 KPI42717.1 - 0.034 14.1 1.9 0.034 14.1 1.3 2.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.1 KPI42717.1 - 0.15 11.2 8.4 0.8 8.8 5.8 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 KPI42717.1 - 0.18 10.9 1.8 14 4.7 0.1 2.9 1 1 1 3 3 3 0 Reovirus sigma C capsid protein TBPIP PF07106.8 KPI42717.1 - 0.24 10.9 7.5 0.43 10.1 1.8 2.6 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cluap1 PF10234.4 KPI42717.1 - 0.28 10.3 9.3 4.6 6.3 0.0 2.5 1 1 1 2 2 2 0 Clusterin-associated protein-1 V-SNARE PF05008.10 KPI42717.1 - 0.29 11.3 6.0 1.3 9.2 3.7 2.5 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Syntaxin-6_N PF09177.6 KPI42717.1 - 0.75 10.2 4.0 1.9 8.9 0.3 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Pox_A_type_inc PF04508.7 KPI42717.1 - 1.3 9.0 11.0 0.79 9.6 0.2 3.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Mnd1 PF03962.10 KPI42717.1 - 3.2 7.3 9.9 0.37 10.4 3.0 2.1 2 1 0 2 2 2 0 Mnd1 family IncA PF04156.9 KPI42717.1 - 4.1 6.9 18.1 0.48 9.9 6.6 2.4 1 1 1 2 2 2 0 IncA protein zf-C2H2_jaz PF12171.3 KPI42718.1 - 0.029 14.5 0.0 0.029 14.5 0.0 2.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding UDPGP PF01704.13 KPI42719.1 - 4.4e-07 28.7 0.0 6.1e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ThiS PF02597.15 KPI42719.1 - 2.9e-06 27.6 0.2 0.018 15.4 0.0 2.5 2 0 0 2 2 2 2 ThiS family MOZ_SAS PF01853.13 KPI42720.1 - 5.1e-75 250.8 0.1 9.2e-75 250.0 0.1 1.4 1 0 0 1 1 1 1 MOZ/SAS family adh_short PF00106.20 KPI42720.1 - 3e-20 72.8 0.1 3e-20 72.8 0.0 2.0 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI42720.1 - 1.1e-12 48.2 0.0 2.5e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI42720.1 - 2.3e-07 30.6 0.0 6.1e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 KR domain PHD PF00628.24 KPI42720.1 - 0.00017 21.1 5.8 0.00017 21.1 4.0 2.1 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.17 KPI42720.1 - 0.91 9.3 5.5 0.26 11.0 0.2 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sugar_tr PF00083.19 KPI42722.1 - 7.9e-73 245.5 18.1 1.7e-70 237.8 12.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI42722.1 - 1.1e-14 53.9 23.8 2.9e-11 42.6 12.0 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily adh_short PF00106.20 KPI42723.1 - 1.2e-20 74.1 0.8 4.5e-20 72.2 0.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI42723.1 - 4.6e-20 72.4 0.1 6.2e-11 42.5 0.0 3.2 3 1 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI42723.1 - 4.9e-07 29.5 0.1 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KPI42723.1 - 0.0039 16.8 0.2 0.01 15.5 0.1 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KPI42723.1 - 0.028 13.5 0.1 0.052 12.6 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KPI42723.1 - 0.13 11.3 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.16 KPI42723.1 - 0.15 11.9 0.4 0.27 11.0 0.3 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Chitin_synth_2 PF03142.10 KPI42724.1 - 3.3e-30 104.9 3.9 1.3e-17 63.4 1.9 2.1 2 0 0 2 2 2 2 Chitin synthase Sugar_tr PF00083.19 KPI42725.1 - 1.8e-67 227.8 15.7 2.2e-67 227.5 10.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI42725.1 - 5.4e-17 61.5 26.9 2.5e-16 59.3 15.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DBR1 PF05011.8 KPI42726.1 - 5.5e-25 87.9 0.0 1e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KPI42726.1 - 5.7e-07 29.1 1.8 2e-06 27.3 1.2 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pribosyl_synth PF14572.1 KPI42727.1 - 2e-43 148.3 2.3 4.8e-36 124.2 0.6 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KPI42727.1 - 1e-31 109.0 0.0 8.5e-31 106.0 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KPI42727.1 - 7.5e-12 45.0 1.5 1e-11 44.6 0.2 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KPI42727.1 - 0.0029 16.8 0.2 0.0047 16.1 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase TMP_2 PF06791.8 KPI42727.1 - 0.046 13.3 0.6 0.071 12.7 0.4 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein Abhydrolase_3 PF07859.8 KPI42728.1 - 5.4e-20 71.8 0.0 7.4e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KPI42728.1 - 2.2e-10 39.7 0.0 5.3e-10 38.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KPI42728.1 - 0.079 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S10 PF00450.17 KPI42728.1 - 0.15 11.1 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase Peptidase_S10 PF00450.17 KPI42729.1 - 4.2e-83 279.8 0.6 6e-83 279.3 0.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase EF-hand_10 PF14788.1 KPI42729.1 - 0.19 11.4 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 EF hand LysM PF01476.15 KPI42730.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 LysM domain MFS_1 PF07690.11 KPI42731.1 - 7.5e-29 100.5 24.1 7.5e-29 100.5 16.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI42731.1 - 1e-05 24.3 32.0 0.0003 19.5 22.2 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_76 PF03663.9 KPI42732.1 - 2.1e-127 425.5 15.0 2.7e-127 425.2 10.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KPI42732.1 - 0.088 11.8 5.4 0.24 10.3 3.8 1.7 1 1 0 1 1 1 0 Glycosyl Hydrolase Family 88 NAD_binding_8 PF13450.1 KPI42733.1 - 3.5e-09 36.5 0.1 8e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KPI42733.1 - 6.2e-06 25.5 0.0 0.00036 19.7 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KPI42733.1 - 0.00016 21.8 0.3 0.00073 19.6 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI42733.1 - 0.0034 16.3 0.0 0.028 13.3 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI42733.1 - 0.0054 16.6 0.0 0.026 14.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KPI42733.1 - 0.02 13.9 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KPI42733.1 - 0.023 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 KPI42733.1 - 0.032 14.0 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KPI42733.1 - 0.073 11.5 0.1 0.15 10.5 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.2 KPI42733.1 - 0.099 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 KPI42733.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Sec1 PF00995.18 KPI42734.1 - 8e-149 496.8 0.0 9.1e-149 496.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF2813 PF11398.3 KPI42734.1 - 0.0016 17.6 0.1 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) ABM PF03992.11 KPI42735.1 - 0.0063 16.5 0.2 0.0099 15.8 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Drc1-Sld2 PF11719.3 KPI42736.1 - 6.2e-70 236.4 40.6 3e-68 230.8 28.2 2.5 1 1 0 1 1 1 1 DNA replication and checkpoint protein Fungal_trans PF04082.13 KPI42738.1 - 7.3e-16 57.8 0.2 1.1e-15 57.2 0.2 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KPI42739.1 - 4.4e-28 98.0 31.3 1.6e-27 96.2 22.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_16 PF00722.16 KPI42740.1 - 3.8e-37 127.3 4.1 3.8e-37 127.3 2.8 2.6 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 LysM PF01476.15 KPI42740.1 - 6.3e-34 115.6 2.7 3.5e-07 30.0 0.0 5.4 5 0 0 5 5 5 5 LysM domain Acyl_transf_3 PF01757.17 KPI42742.1 - 2.4e-15 56.2 30.7 2.2e-13 49.7 21.3 2.6 1 1 0 1 1 1 1 Acyltransferase family Spt20 PF12090.3 KPI42743.1 - 2e-40 138.0 0.0 2e-40 138.0 0.0 4.9 3 2 0 3 3 3 1 Spt20 family FA_hydroxylase PF04116.8 KPI42744.1 - 1.8e-12 47.6 4.6 1.8e-12 47.6 3.2 2.6 3 1 0 3 3 3 1 Fatty acid hydroxylase superfamily DUF3247 PF11607.3 KPI42745.1 - 0.062 13.5 0.0 0.077 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) adh_short PF00106.20 KPI42747.1 - 2.5e-32 112.1 1.0 3.9e-32 111.4 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI42747.1 - 3e-28 99.2 0.1 4.2e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI42747.1 - 1.4e-13 50.9 1.3 3.2e-13 49.7 0.9 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KPI42747.1 - 4.1e-06 25.9 0.1 7.8e-06 24.9 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 KPI42747.1 - 0.0061 16.3 0.2 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.16 KPI42747.1 - 0.016 14.6 0.3 0.28 10.6 0.0 2.5 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KPI42747.1 - 0.073 12.8 0.9 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_16 PF10294.4 KPI42748.1 - 1.2e-22 80.1 0.0 1.8e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KPI42748.1 - 3e-06 27.0 0.0 1.3e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI42748.1 - 0.00016 22.2 0.0 0.00029 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KPI42748.1 - 0.0019 17.6 0.0 0.0039 16.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KPI42748.1 - 0.012 14.8 0.0 0.028 13.5 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) TauD PF02668.11 KPI42749.1 - 4.8e-41 141.1 0.1 5.6e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KPI42749.1 - 0.008 15.1 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 CsiD 2OG-FeII_Oxy_3 PF13640.1 KPI42749.1 - 0.02 15.4 0.0 0.11 13.0 0.0 2.1 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily PAN_3 PF08277.7 KPI42750.1 - 0.11 12.1 0.2 0.32 10.6 0.0 1.8 2 0 0 2 2 2 0 PAN-like domain Phage-MuB_C PF09077.6 KPI42751.1 - 0.089 12.4 0.4 0.2 11.3 0.3 1.5 1 0 0 1 1 1 0 Mu B transposition protein, C terminal zf-C4H2 PF10146.4 KPI42751.1 - 0.098 12.6 0.2 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein PDEase_I PF00233.14 KPI42752.1 - 4.8e-47 160.7 0.0 9.3e-43 146.6 0.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Amidase PF01425.16 KPI42753.1 - 1.1e-87 294.7 0.0 1.5e-87 294.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Anophelin PF10731.4 KPI42754.1 - 8.8 6.5 6.0 19 5.4 4.1 1.6 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito DUF3328 PF11807.3 KPI42755.1 - 8.1e-53 179.3 0.0 1e-52 179.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) WD40 PF00400.27 KPI42756.1 - 7.4e-08 31.9 1.4 0.0048 16.7 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF3419 PF11899.3 KPI42758.1 - 1.7e-145 484.5 0.0 2.6e-145 483.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_31 PF13847.1 KPI42758.1 - 2.1e-10 40.4 0.0 9.6e-10 38.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI42758.1 - 1.2e-09 38.5 0.0 2.6e-08 34.2 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI42758.1 - 1.2e-09 38.0 0.0 2.4e-08 33.8 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI42758.1 - 8.7e-09 35.7 0.0 7.4e-08 32.7 0.0 2.6 2 1 1 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI42758.1 - 2.6e-08 33.2 0.0 5.9e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KPI42758.1 - 1.1e-07 32.3 0.0 4.1e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI42758.1 - 1.7e-06 28.3 0.0 4.4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI42758.1 - 2.2e-06 27.7 0.0 7.5e-05 22.7 0.0 3.1 4 0 0 4 4 4 1 Methyltransferase domain PCMT PF01135.14 KPI42758.1 - 1.6e-05 24.5 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AMP-binding PF00501.23 KPI42759.1 - 1.5e-29 102.6 0.1 8.2e-25 87.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Thiolase_N PF00108.18 KPI42760.1 - 2.3e-77 259.5 0.3 3e-77 259.1 0.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KPI42760.1 - 9.1e-39 131.6 0.2 2.8e-38 130.0 0.1 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KPI42760.1 - 0.023 14.3 1.1 1.6 8.4 0.2 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Tannase PF07519.6 KPI42761.1 - 1.9e-109 366.5 0.3 2.3e-109 366.2 0.2 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KPI42761.1 - 9.8e-06 25.6 0.0 2.6e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI42761.1 - 1.3e-05 25.0 0.1 0.00058 19.6 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI42761.1 - 0.0067 16.0 0.2 0.01 15.4 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold polyprenyl_synt PF00348.12 KPI42763.1 - 2.1e-48 164.4 0.0 1.4e-45 155.1 0.0 2.2 2 0 0 2 2 2 2 Polyprenyl synthetase AMMECR1 PF01871.12 KPI42763.1 - 5e-38 129.8 0.0 9.4e-38 129.0 0.0 1.3 1 0 0 1 1 1 1 AMMECR1 HEPPP_synt_1 PF07307.6 KPI42763.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Herpes_gE PF02480.11 KPI42764.1 - 0.014 13.6 0.2 0.018 13.3 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF605 PF04652.11 KPI42764.1 - 0.03 13.7 4.2 0.033 13.5 2.9 1.0 1 0 0 1 1 1 0 Vta1 like Pex14_N PF04695.8 KPI42764.1 - 0.16 11.9 1.4 0.25 11.4 0.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SOG2 PF10428.4 KPI42764.1 - 7.5 5.0 8.5 9.9 4.6 5.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Lipocalin_5 PF13924.1 KPI42765.1 - 3.9e-25 88.1 0.3 4.5e-25 87.9 0.2 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Aldo_ket_red PF00248.16 KPI42766.1 - 2.3e-51 174.2 0.0 3.1e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CENP-X PF09415.5 KPI42767.1 - 1.5e-16 59.9 0.0 2.7e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Dicty_REP PF05086.7 KPI42767.1 - 0.064 11.0 14.8 0.074 10.8 10.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MIP-T3 PF10243.4 KPI42767.1 - 0.68 8.3 16.5 0.77 8.1 11.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ebola_NP PF05505.7 KPI42767.1 - 0.69 7.9 9.9 0.75 7.7 6.9 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Suf PF05843.9 KPI42767.1 - 6.5 6.3 8.4 8.6 5.9 5.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.5 KPI42767.1 - 6.8 4.9 6.5 7.4 4.8 4.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NYN PF01936.13 KPI42768.1 - 0.0001 22.6 0.0 0.00042 20.6 0.0 1.9 1 1 0 1 1 1 1 NYN domain MFS_1 PF07690.11 KPI42769.1 - 2e-31 109.0 42.5 6.4e-28 97.4 23.1 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KPI42769.1 - 2.3e-06 26.1 2.9 3.9e-06 25.3 2.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 KPI42769.1 - 0.044 13.8 0.2 0.044 13.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Abhydrolase_6 PF12697.2 KPI42770.1 - 1.2e-11 44.9 6.2 2e-11 44.2 4.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI42770.1 - 1.3e-06 28.2 0.1 1.8e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.11 KPI42770.1 - 0.044 13.1 0.0 0.32 10.3 0.0 2.1 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.3 KPI42770.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_6 PF12697.2 KPI42771.1 - 2.5e-31 109.3 0.0 3.2e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI42771.1 - 1.7e-20 73.5 0.0 1.2e-18 67.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI42771.1 - 1.4e-15 57.3 0.0 1.4e-14 54.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KPI42771.1 - 1.2e-05 24.6 0.0 0.0011 18.3 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KPI42771.1 - 1.7e-05 24.3 0.0 0.0036 16.7 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KPI42771.1 - 7.7e-05 22.0 0.1 0.0095 15.1 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 KPI42771.1 - 0.00014 21.7 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.8 KPI42771.1 - 0.0038 16.6 0.1 0.0085 15.5 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Esterase PF00756.15 KPI42771.1 - 0.0097 15.3 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 KPI42771.1 - 0.012 15.0 0.0 0.031 13.7 0.0 1.6 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S10 PF00450.17 KPI42771.1 - 0.17 10.9 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase DUF1768 PF08719.6 KPI42773.1 - 7.7e-28 97.2 0.0 1.2e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) ATP-grasp_2 PF08442.5 KPI42774.1 - 4e-80 267.9 0.5 6.6e-80 267.2 0.3 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KPI42774.1 - 1.4e-24 86.4 0.8 3.5e-24 85.1 0.5 1.7 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KPI42774.1 - 2.9e-08 33.2 0.1 6.3e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KPI42774.1 - 0.0044 16.6 1.2 0.011 15.3 0.1 2.1 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 KPI42774.1 - 0.04 13.4 0.0 0.42 10.0 0.0 2.5 1 1 2 3 3 3 0 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.1 KPI42774.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Acyl_transf_3 PF01757.17 KPI42776.1 - 2.6e-19 69.2 27.1 2.8e-18 65.8 18.8 2.1 1 1 0 1 1 1 1 Acyltransferase family Proteasom_Rpn13 PF04683.8 KPI42777.1 - 2.5e-26 91.5 0.0 4.1e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Pyr_redox_3 PF13738.1 KPI42778.1 - 1.1e-18 68.0 0.0 1.9e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI42778.1 - 2.3e-15 55.8 0.6 7.5e-13 47.5 0.7 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI42778.1 - 7.6e-09 35.4 0.0 4.3e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI42778.1 - 8.4e-07 28.2 0.3 6.2e-05 22.0 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KPI42778.1 - 0.00012 21.8 0.0 0.23 11.2 0.0 3.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 KPI42778.1 - 0.0036 17.0 0.0 0.47 10.1 0.0 2.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MIB_HERC2 PF06701.8 KPI42778.1 - 0.12 12.3 1.4 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 Mib_herc2 DUF2178 PF09946.4 KPI42778.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) Sugar_tr PF00083.19 KPI42779.1 - 1.1e-39 136.3 19.7 1.4e-39 135.9 13.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI42779.1 - 2e-08 33.3 16.2 2e-08 33.3 11.2 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily APG9 PF04109.11 KPI42780.1 - 6.8e-161 535.2 6.4 1.2e-160 534.5 4.4 1.3 1 0 0 1 1 1 1 Autophagy protein Apg9 MtN3_slv PF03083.11 KPI42780.1 - 0.043 13.6 2.4 0.11 12.3 1.7 1.7 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange PhyH PF05721.8 KPI42781.1 - 4.6e-12 46.4 0.0 1.1e-11 45.1 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Nop PF01798.13 KPI42783.1 - 7e-56 187.6 0.6 2.2e-55 186.0 0.4 1.8 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KPI42783.1 - 5.1e-27 93.4 0.1 9.8e-27 92.5 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KPI42783.1 - 1.4e-21 76.4 2.9 6.2e-21 74.3 2.0 2.2 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DUF605 PF04652.11 KPI42785.1 - 1.8 7.8 8.6 2 7.7 6.0 1.0 1 0 0 1 1 1 0 Vta1 like Pol_alpha_B_N PF08418.5 KPI42785.1 - 4.6 6.6 9.1 5.9 6.3 6.3 1.2 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF607 PF04678.8 KPI42787.1 - 4.5e-44 150.5 1.0 3.2e-43 147.7 0.2 2.6 2 1 0 2 2 2 1 Protein of unknown function, DUF607 RasGAP PF00616.14 KPI42788.1 - 4e-45 153.9 0.0 1.2e-44 152.4 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KPI42788.1 - 0.0032 17.2 0.0 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 C2 domain Troponin-I_N PF11636.3 KPI42789.1 - 0.0008 19.0 2.1 0.0014 18.2 1.5 1.4 1 0 0 1 1 1 1 Troponin I residues 1-32 PDE6_gamma PF04868.7 KPI42789.1 - 4.7 7.1 5.3 1.1 9.1 0.8 2.0 2 1 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit Sugar_tr PF00083.19 KPI42790.1 - 1.2e-55 188.9 23.8 1.3e-54 185.5 17.6 1.6 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI42790.1 - 1.5e-10 40.3 31.0 3e-10 39.3 21.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KPI42790.1 - 1.7e-06 26.6 24.3 0.00086 17.8 4.4 3.2 3 1 0 3 3 3 2 MFS/sugar transport protein HET PF06985.6 KPI42792.1 - 8.9e-27 93.9 0.0 1.4e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans_2 PF11951.3 KPI42793.1 - 2.2e-10 39.7 0.4 4.5e-10 38.6 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KPI42794.1 - 7e-34 117.0 37.5 1e-33 116.5 26.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FeoB_C PF07664.7 KPI42794.1 - 0.27 10.6 4.9 1.5 8.2 0.1 3.5 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus DHH PF01368.15 KPI42795.1 - 0.013 15.1 0.0 0.034 13.8 0.0 1.6 1 1 0 1 1 1 0 DHH family PCI PF01399.22 KPI42796.1 - 1e-06 29.0 1.5 4.3e-06 26.9 0.2 2.5 2 1 0 2 2 2 1 PCI domain YfdX PF10938.3 KPI42796.1 - 0.041 13.5 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 YfdX protein DUF1912 PF08930.5 KPI42796.1 - 0.34 11.0 2.6 2.5 8.2 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1912) Fungal_trans PF04082.13 KPI42797.1 - 1.9e-09 36.8 0.0 6.1e-09 35.1 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI42797.1 - 0.034 14.0 0.6 0.07 13.0 0.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxysterol_BP PF01237.13 KPI42798.1 - 4.7e-83 278.6 0.1 5.9e-83 278.2 0.1 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein dCMP_cyt_deam_1 PF00383.17 KPI42798.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region DUF814 PF05670.8 KPI42799.1 - 2e-16 59.6 0.0 3.4e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF814) DUF1675 PF07897.6 KPI42799.1 - 0.07 12.9 3.0 0.09 12.6 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) BSMAP PF12280.3 KPI42799.1 - 0.12 12.2 1.8 0.16 11.8 1.3 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein Pkinase_Tyr PF07714.12 KPI42800.1 - 3e-08 33.0 0.0 3.7e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KPI42800.1 - 0.00023 20.4 0.0 0.00059 19.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain VHP PF02209.14 KPI42801.1 - 0.19 11.4 0.3 0.31 10.7 0.2 1.3 1 0 0 1 1 1 0 Villin headpiece domain ABC_tran PF00005.22 KPI42802.1 - 5.1e-48 162.8 0.2 3e-24 85.8 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KPI42802.1 - 2e-15 57.5 3.7 0.0013 18.7 0.0 4.4 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 KPI42802.1 - 1.1e-14 54.2 0.0 4e-06 26.2 0.0 3.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KPI42802.1 - 1.3e-09 38.6 2.1 0.00093 19.5 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KPI42802.1 - 2.7e-09 36.4 0.1 0.0017 17.8 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_28 PF13521.1 KPI42802.1 - 3.5e-07 30.3 0.1 0.015 15.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KPI42802.1 - 7.3e-07 29.3 0.0 0.0095 16.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KPI42802.1 - 7.3e-07 30.0 0.5 0.0083 16.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 KPI42802.1 - 9.9e-07 28.0 0.0 0.00083 18.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 KPI42802.1 - 2.1e-06 27.0 6.1 0.046 12.7 0.0 4.5 3 2 2 5 5 5 2 AAA ATPase domain SbcCD_C PF13558.1 KPI42802.1 - 2.1e-06 27.5 0.0 0.02 14.8 0.0 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.24 KPI42802.1 - 4.2e-06 27.0 0.1 0.071 13.3 0.1 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KPI42802.1 - 5.3e-06 25.9 0.0 0.15 11.5 0.0 2.8 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 KPI42802.1 - 1.1e-05 25.3 0.0 0.23 11.3 0.0 3.6 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 KPI42802.1 - 1.2e-05 25.8 0.1 0.029 14.8 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KPI42802.1 - 1.2e-05 25.1 0.0 0.018 14.9 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.7 KPI42802.1 - 1.3e-05 24.9 0.0 0.019 14.6 0.0 2.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KPI42802.1 - 2.3e-05 24.4 0.0 0.45 10.4 0.0 3.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_10 PF12846.2 KPI42802.1 - 3.9e-05 23.2 0.3 0.32 10.3 0.0 3.0 3 0 0 3 3 3 2 AAA-like domain AAA_18 PF13238.1 KPI42802.1 - 5.8e-05 23.4 0.3 0.42 10.9 0.0 3.7 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 KPI42802.1 - 0.00013 21.6 0.0 0.66 9.6 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B HEAT_2 PF13646.1 KPI42802.1 - 0.00013 22.1 0.4 2.6 8.3 0.0 3.8 1 1 2 4 4 4 1 HEAT repeats ArgK PF03308.11 KPI42802.1 - 0.00015 20.6 0.1 0.17 10.6 0.0 2.9 2 0 0 2 2 2 2 ArgK protein cobW PF02492.14 KPI42802.1 - 0.00025 20.5 0.2 0.54 9.6 0.0 3.6 3 1 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KPI42802.1 - 0.00029 20.9 0.1 0.56 10.4 0.0 3.1 3 0 0 3 3 2 1 RNA helicase Arch_ATPase PF01637.13 KPI42802.1 - 0.00033 20.4 0.2 0.25 10.9 0.0 3.0 3 0 0 3 3 2 1 Archaeal ATPase Dynamin_N PF00350.18 KPI42802.1 - 0.00035 20.4 0.1 0.0079 16.0 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_14 PF13173.1 KPI42802.1 - 0.00067 19.5 0.2 1.8 8.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 KPI42802.1 - 0.00097 19.0 2.2 0.22 11.3 0.1 3.4 3 1 0 3 3 2 1 Domain of unknown function DUF87 AAA_30 PF13604.1 KPI42802.1 - 0.0016 18.0 0.0 1.9 8.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.20 KPI42802.1 - 0.0017 17.9 0.0 1.6 8.2 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 KPI42802.1 - 0.0034 16.7 0.0 2.7 7.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KPI42802.1 - 0.0037 16.4 0.1 2.5 7.1 0.0 3.0 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KPI42802.1 - 0.0055 16.4 0.1 5.8 6.7 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain ATP_bind_1 PF03029.12 KPI42802.1 - 0.0062 16.1 0.1 3.9 6.9 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein HEAT PF02985.17 KPI42802.1 - 0.0063 16.4 0.0 19 5.6 0.0 4.1 4 0 0 4 4 3 0 HEAT repeat NB-ARC PF00931.17 KPI42802.1 - 0.015 14.1 0.9 0.21 10.3 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain T2SE PF00437.15 KPI42802.1 - 0.017 14.0 0.1 4.4 6.1 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_5 PF07728.9 KPI42802.1 - 0.022 14.5 0.0 13 5.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 KPI42802.1 - 0.025 13.2 0.1 0.93 8.1 0.0 2.7 2 0 0 2 2 2 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.13 KPI42802.1 - 0.026 14.0 0.3 1.5 8.2 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 KPI42802.1 - 0.046 13.1 0.0 13 5.1 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein Septin PF00735.13 KPI42802.1 - 0.05 12.6 0.9 1.6 7.6 0.0 2.6 3 0 0 3 3 2 0 Septin UPF0079 PF02367.12 KPI42802.1 - 0.055 13.0 0.5 3.7 7.1 0.0 2.8 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_13 PF13166.1 KPI42802.1 - 0.055 11.9 8.5 0.66 8.3 0.0 3.7 5 0 0 5 5 4 0 AAA domain Adaptin_N PF01602.15 KPI42802.1 - 0.068 11.4 0.3 8.2 4.6 0.0 2.8 2 1 1 3 3 3 0 Adaptin N terminal region Hydrolase PF00702.21 KPI42803.1 - 2e-45 155.8 1.3 1.7e-44 152.7 0.2 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KPI42803.1 - 3.1e-41 140.9 0.1 5.1e-20 71.4 0.0 2.9 2 1 1 3 3 3 2 E1-E2 ATPase HMA PF00403.21 KPI42803.1 - 3.4e-41 139.1 0.1 4.9e-12 45.7 0.0 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 KPI42803.1 - 2.9e-12 47.1 0.0 1.8e-11 44.6 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KPI42803.1 - 0.017 14.6 1.7 0.02 14.4 0.3 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase B12-binding PF02310.14 KPI42803.1 - 0.021 14.7 0.1 4 7.3 0.0 3.5 3 0 0 3 3 3 0 B12 binding domain Sugar_tr PF00083.19 KPI42804.1 - 4.1e-09 35.5 0.3 4.7e-09 35.3 0.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI42805.1 - 1.3e-41 142.5 46.2 8.8e-40 136.4 32.2 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KPI42805.1 - 8.9e-16 57.1 8.7 8.9e-16 57.1 6.0 2.4 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Beta-lactamase PF00144.19 KPI42806.1 - 9.3e-54 182.6 0.0 1.2e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Dynein_light PF01221.13 KPI42808.1 - 2.3e-41 139.6 2.2 2.7e-41 139.4 1.5 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_M24 PF00557.19 KPI42808.1 - 0.1 12.1 0.1 0.11 12.0 0.1 1.0 1 0 0 1 1 1 0 Metallopeptidase family M24 Ground-like PF04155.13 KPI42808.1 - 0.12 12.7 0.2 0.17 12.1 0.2 1.3 1 0 0 1 1 1 0 Ground-like domain Rtf2 PF04641.7 KPI42809.1 - 7.5e-60 202.3 2.1 8.8e-60 202.0 1.4 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 KPI42809.1 - 3.1e-06 26.5 0.0 0.073 12.5 0.0 2.3 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 KPI42809.1 - 0.0047 16.7 0.6 0.046 13.5 0.1 2.6 2 1 1 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.1 KPI42809.1 - 0.011 15.3 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KPI42809.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MatP PF06303.7 KPI42809.1 - 0.16 11.9 2.6 0.25 11.2 1.8 1.3 1 0 0 1 1 1 0 Organiser of macrodomain of Terminus of chromosome Dehydrin PF00257.14 KPI42809.1 - 0.2 11.9 11.9 0.34 11.2 8.2 1.4 1 0 0 1 1 1 0 Dehydrin DUF4588 PF15251.1 KPI42811.1 - 7.1e-06 26.1 9.0 1.3e-05 25.3 6.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) MSA-2c PF12238.3 KPI42811.1 - 4.7 6.8 10.1 0.12 12.0 0.8 2.1 2 0 0 2 2 2 0 Merozoite surface antigen 2c Zn_clus PF00172.13 KPI42812.1 - 1.7e-06 27.8 11.2 1.7e-06 27.8 7.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 3-PAP PF12578.3 KPI42812.1 - 0.011 15.5 1.9 0.011 15.5 1.3 2.2 1 1 1 2 2 2 0 Myotubularin-associated protein Tmemb_cc2 PF10267.4 KPI42812.1 - 0.26 9.8 6.5 0.49 8.9 4.5 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF3425 PF11905.3 KPI42814.1 - 5e-16 58.8 0.3 9.1e-16 57.9 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) LysM PF01476.15 KPI42816.1 - 0.0003 20.6 0.0 0.00055 19.7 0.0 1.5 1 0 0 1 1 1 1 LysM domain Nucleos_tra2_C PF07662.8 KPI42817.1 - 6.1e-70 234.9 1.6 6.1e-70 234.9 1.1 2.1 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KPI42817.1 - 1e-22 80.2 1.4 1e-22 80.2 1.0 3.3 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus ATP1G1_PLM_MAT8 PF02038.11 KPI42817.1 - 0.87 8.6 2.7 2.7 7.0 1.9 1.8 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Gate PF07670.9 KPI42817.1 - 1.1 9.1 20.2 0.12 12.3 8.8 3.3 3 1 0 3 3 3 0 Nucleoside recognition Aldo_ket_red PF00248.16 KPI42818.1 - 1.7e-49 168.1 0.0 2.4e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.2 KPI42819.1 - 1.6e-06 27.6 0.0 3.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like CAF-1_p150 PF11600.3 KPI42820.1 - 0.13 11.6 11.2 0.31 10.3 7.7 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Borrelia_P83 PF05262.6 KPI42820.1 - 0.56 8.4 3.7 0.67 8.1 2.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Thi4 PF01946.12 KPI42821.1 - 8.5e-78 260.5 0.4 5.4e-77 257.9 0.2 1.9 1 1 0 1 1 1 1 Thi4 family DAO PF01266.19 KPI42821.1 - 1.6e-06 27.2 0.4 9.2e-06 24.7 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KPI42821.1 - 4.7e-06 25.7 0.9 2.3e-05 23.5 0.6 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KPI42821.1 - 8.3e-06 24.8 3.2 0.00025 20.0 1.3 2.3 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KPI42821.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI42821.1 - 4.6e-05 23.3 0.3 0.00019 21.3 0.2 2.2 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KPI42821.1 - 0.0018 17.3 0.2 0.0026 16.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KPI42821.1 - 0.003 16.4 0.6 0.0061 15.4 0.4 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 KPI42821.1 - 0.003 16.2 0.2 0.0043 15.7 0.2 1.2 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.9 KPI42821.1 - 0.0042 15.6 0.3 0.0062 15.0 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KPI42821.1 - 0.021 13.9 1.0 0.15 11.1 0.4 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KPI42821.1 - 0.05 13.6 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 KPI42821.1 - 0.052 13.6 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI42821.1 - 0.066 12.9 0.8 0.14 11.9 0.0 2.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Mqo PF06039.10 KPI42821.1 - 0.12 10.4 0.0 0.18 9.9 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Actin PF00022.14 KPI42822.1 - 7e-23 80.6 0.0 9.4e-19 67.0 0.0 2.4 2 1 0 2 2 2 2 Actin CUE PF02845.11 KPI42823.1 - 1.8e-06 27.2 0.0 3.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain UBA PF00627.26 KPI42823.1 - 0.0028 17.4 0.0 0.0059 16.4 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain SDA1 PF05285.7 KPI42824.1 - 8.1e-65 219.2 51.6 3.7e-45 154.6 12.8 3.2 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.7 KPI42824.1 - 4.2e-21 74.9 0.2 1.3e-20 73.3 0.2 1.9 1 0 0 1 1 1 1 NUC130/3NT domain RecR PF02132.10 KPI42825.1 - 0.12 11.8 0.7 1 8.8 0.0 2.1 2 0 0 2 2 2 0 RecR protein AAA_2 PF07724.9 KPI42826.1 - 3.1e-47 160.6 0.0 6e-46 156.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KPI42826.1 - 6.7e-27 94.2 0.0 1.3e-14 54.5 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KPI42826.1 - 8.4e-23 80.0 1.2 8.4e-23 80.0 0.8 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 KPI42826.1 - 9.6e-16 58.2 11.7 1e-05 25.5 0.0 6.3 4 2 3 8 8 7 2 AAA ATPase domain AAA_5 PF07728.9 KPI42826.1 - 3.2e-15 56.0 0.0 9.2e-10 38.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KPI42826.1 - 3.7e-14 52.9 0.4 4.5e-05 23.6 0.0 4.7 4 1 1 5 5 4 2 AAA domain Sigma54_activat PF00158.21 KPI42826.1 - 9.9e-09 34.8 0.0 4.1e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.1 KPI42826.1 - 1e-07 32.3 0.3 0.018 15.3 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 KPI42826.1 - 2.8e-07 30.1 0.4 0.031 14.0 0.1 3.6 3 0 0 3 3 3 2 Part of AAA domain Arch_ATPase PF01637.13 KPI42826.1 - 3.1e-07 30.3 1.9 0.0036 17.0 0.1 4.9 3 1 0 3 3 3 1 Archaeal ATPase AAA_17 PF13207.1 KPI42826.1 - 3.1e-07 31.2 6.0 0.0098 16.7 0.0 3.9 3 2 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 KPI42826.1 - 3.2e-07 29.9 0.0 0.024 14.0 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Clp_N PF02861.15 KPI42826.1 - 2e-06 27.6 1.8 0.021 14.7 0.1 3.4 3 0 0 3 3 2 2 Clp amino terminal domain AAA_28 PF13521.1 KPI42826.1 - 1.2e-05 25.3 1.2 0.23 11.4 0.0 3.8 3 1 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 KPI42826.1 - 1.7e-05 24.0 0.1 0.13 11.3 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KPI42826.1 - 3.6e-05 23.6 0.0 0.22 11.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KPI42826.1 - 7.3e-05 22.8 0.0 0.48 10.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 KPI42826.1 - 0.0001 22.6 0.4 0.36 11.1 0.0 3.5 3 0 0 3 3 3 1 ABC transporter MobB PF03205.9 KPI42826.1 - 0.00011 21.9 0.0 0.81 9.3 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 KPI42826.1 - 0.00031 20.3 0.0 0.99 9.0 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KPI42826.1 - 0.00037 20.0 2.4 0.11 11.9 0.0 4.2 4 1 0 4 4 4 1 AAA-like domain AAA_25 PF13481.1 KPI42826.1 - 0.00047 19.6 0.8 2.3 7.5 0.0 4.1 4 1 0 5 5 3 2 AAA domain Zeta_toxin PF06414.7 KPI42826.1 - 0.00047 19.3 0.0 0.1 11.6 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin Torsin PF06309.6 KPI42826.1 - 0.00059 19.7 0.0 0.0067 16.3 0.0 2.2 2 0 0 2 2 2 1 Torsin ResIII PF04851.10 KPI42826.1 - 0.00061 19.6 1.4 0.25 11.1 0.0 3.9 4 1 1 5 5 3 1 Type III restriction enzyme, res subunit DUF258 PF03193.11 KPI42826.1 - 0.00065 18.9 0.1 0.31 10.1 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KPI42826.1 - 0.00066 19.1 0.0 0.5 9.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.1 KPI42826.1 - 0.0013 18.3 0.0 0.95 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 KPI42826.1 - 0.0046 16.4 0.0 1.7 8.0 0.0 3.1 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain NACHT PF05729.7 KPI42826.1 - 0.0053 16.4 0.0 0.78 9.3 0.0 3.0 3 0 0 3 3 3 1 NACHT domain NTPase_1 PF03266.10 KPI42826.1 - 0.0054 16.4 0.0 0.43 10.2 0.0 3.3 3 0 0 3 3 3 1 NTPase MMR_HSR1 PF01926.18 KPI42826.1 - 0.0057 16.6 0.0 0.12 12.2 0.0 3.3 3 1 0 3 3 2 1 50S ribosome-binding GTPase AAA_21 PF13304.1 KPI42826.1 - 0.0091 15.9 0.0 2.2 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KPI42826.1 - 0.044 13.3 0.0 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.4 KPI42826.1 - 0.051 13.0 0.0 7.5 6.0 0.0 3.0 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 KPI42826.1 - 0.073 12.7 0.0 20 4.8 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Beta_elim_lyase PF01212.16 KPI42827.1 - 3.5e-45 154.3 0.0 4.4e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KPI42827.1 - 4.2e-06 25.9 0.0 6.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II PepSY_TM_2 PF13703.1 KPI42828.1 - 0.0063 16.6 5.1 0.18 11.9 0.2 2.5 2 1 0 2 2 2 2 PepSY-associated TM helix ELO PF01151.13 KPI42829.1 - 9e-83 277.4 8.9 1.1e-82 277.0 6.2 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Apolipoprotein PF01442.13 KPI42829.1 - 0.003 17.0 6.8 0.003 17.0 4.7 2.0 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Prominin PF05478.6 KPI42829.1 - 8.7 3.7 8.9 14 3.0 6.1 1.2 1 0 0 1 1 1 0 Prominin Bul1_N PF04425.7 KPI42830.1 - 4.5e-06 25.4 0.0 9.4e-06 24.4 0.0 1.4 1 0 0 1 1 1 1 Bul1 N terminus Arrestin_N PF00339.24 KPI42830.1 - 2.4e-05 24.2 0.0 4.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 KPI42830.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Bul1 C terminus Aminotran_3 PF00202.16 KPI42831.1 - 5.6e-57 193.1 0.0 9.8e-57 192.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III AAT PF03417.11 KPI42831.1 - 1.5e-25 89.9 0.0 2.3e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 KPI42831.1 - 0.00061 20.0 0.0 0.0016 18.7 0.0 1.8 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF2713 PF10897.3 KPI42831.1 - 0.082 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) PaRep2b PF07775.6 KPI42831.1 - 0.14 10.3 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 PaRep2b protein HET PF06985.6 KPI42833.1 - 1.4e-32 112.7 0.4 2.1e-32 112.1 0.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) OTCace PF00185.19 KPI42834.1 - 5.6e-40 136.7 0.0 1.1e-39 135.8 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 KPI42834.1 - 5e-38 129.9 0.0 8.7e-38 129.1 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Fungal_trans PF04082.13 KPI42835.1 - 7e-08 31.6 0.3 1.1e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.1 KPI42836.1 - 2.7e-27 96.0 0.0 3.4e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI42836.1 - 9e-24 84.2 0.1 1.2e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI42836.1 - 2.9e-10 40.1 0.1 7.8e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI42836.1 - 0.00015 21.3 0.1 0.00042 19.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI42836.1 - 0.00032 20.7 0.2 0.00063 19.8 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KPI42838.1 - 9.8e-17 61.3 0.5 1.5e-16 60.7 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI42838.1 - 2.4e-08 33.8 0.2 3.1e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KPI42838.1 - 0.0012 17.7 0.1 0.0017 17.3 0.1 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KPI42838.1 - 0.0019 18.2 0.5 0.011 15.7 0.4 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI42838.1 - 0.0027 17.1 0.2 0.0039 16.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Toprim_3 PF13362.1 KPI42838.1 - 0.089 13.0 0.2 0.81 9.9 0.1 2.3 2 1 0 2 2 2 0 Toprim domain BTB PF00651.26 KPI42839.1 - 0.00022 21.1 0.0 0.00056 19.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain MLTD_N PF06474.7 KPI42840.1 - 1.3 9.2 5.3 0.78 9.9 1.7 2.2 2 0 0 2 2 2 0 MltD lipid attachment motif Pkinase PF00069.20 KPI42841.1 - 6.6e-61 205.7 0.0 8.5e-61 205.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI42841.1 - 1e-27 96.8 0.0 1.4e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KPI42841.1 - 4.8e-05 23.7 0.7 0.0012 19.3 0.1 2.6 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KPI42841.1 - 0.019 13.9 0.0 0.063 12.2 0.0 1.8 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 KPI42841.1 - 0.072 12.8 0.1 5.7 6.5 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Tcf25 PF04910.9 KPI42842.1 - 8.6e-79 265.0 0.3 1.3e-78 264.4 0.2 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DUF4119 PF13494.1 KPI42842.1 - 0.25 11.3 0.3 0.53 10.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) TATR PF03430.8 KPI42842.1 - 3.8 6.0 4.9 5.8 5.4 3.4 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF4013 PF13197.1 KPI42843.1 - 0.039 13.3 3.5 0.8 9.0 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) ORC6 PF05460.8 KPI42843.1 - 0.058 12.4 3.1 0.073 12.1 2.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Claudin_2 PF13903.1 KPI42843.1 - 0.39 10.4 6.4 0.32 10.6 0.9 2.7 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Amidohydro_4 PF13147.1 KPI42844.1 - 1.3e-11 45.1 0.8 3e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KPI42844.1 - 1.5e-09 37.9 0.1 8.5e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 KPI42844.1 - 1e-08 34.8 0.0 1.5e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KPI42844.1 - 4.7e-05 23.1 0.0 0.00011 21.8 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase DFP PF04127.10 KPI42845.1 - 1.5e-16 60.5 0.0 2.5e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein UQ_con PF00179.21 KPI42846.1 - 4.3e-48 162.3 0.1 4.8e-48 162.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KPI42846.1 - 0.00032 20.4 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KPI42846.1 - 0.17 11.7 0.8 0.3 10.9 0.5 1.6 1 1 0 1 1 1 0 RWD domain LRR_4 PF12799.2 KPI42847.1 - 1.2e-10 40.7 11.1 0.004 16.7 0.0 4.3 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KPI42847.1 - 2.9e-07 29.8 13.1 0.15 12.2 0.7 5.4 5 0 0 5 5 5 2 Leucine Rich repeat LRR_8 PF13855.1 KPI42847.1 - 1.6e-05 24.5 12.2 0.0032 17.1 1.7 3.7 1 1 3 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KPI42847.1 - 1.8e-05 24.1 18.0 0.11 12.5 0.5 6.1 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 KPI42847.1 - 0.00011 21.8 8.8 4 8.0 0.2 5.2 5 0 0 5 5 5 2 Leucine rich repeat PBP1_TM PF14812.1 KPI42847.1 - 0.38 11.0 2.3 0.64 10.3 1.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal XPC-binding PF09280.6 KPI42849.1 - 1.2e-22 79.1 7.0 3.1e-22 77.7 4.9 1.7 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 KPI42849.1 - 1.9e-08 33.8 0.0 5.5e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain MCM_N PF14551.1 KPI42849.1 - 0.00069 20.1 0.1 0.018 15.5 0.0 2.5 2 0 0 2 2 2 1 MCM N-terminal domain GCV_T_C PF08669.6 KPI42849.1 - 0.092 12.7 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Ribosomal_S8 PF00410.14 KPI42850.1 - 6.7e-25 87.4 0.1 9.3e-25 86.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Actin PF00022.14 KPI42851.1 - 1.7e-130 434.9 0.0 2e-130 434.7 0.0 1.0 1 0 0 1 1 1 1 Actin Asn_synthase PF00733.16 KPI42852.1 - 4e-68 229.6 0.0 5.7e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KPI42852.1 - 1.4e-30 105.5 0.0 2.8e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KPI42852.1 - 3.5e-21 75.5 0.0 8.9e-21 74.2 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KPI42852.1 - 1.4e-07 31.0 0.1 4.5e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Aluminium induced protein GATase_2 PF00310.16 KPI42852.1 - 0.0012 17.6 0.0 1.1 7.9 0.0 2.9 1 1 2 3 3 3 2 Glutamine amidotransferases class-II NAD_synthase PF02540.12 KPI42852.1 - 0.016 14.1 0.0 0.038 12.9 0.0 1.6 1 1 0 1 1 1 0 NAD synthase Adap_comp_sub PF00928.16 KPI42854.1 - 2.3e-49 167.8 0.0 3.4e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KPI42854.1 - 0.0033 17.1 0.0 0.0053 16.4 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SLAC1 PF03595.12 KPI42855.1 - 2.4e-72 243.4 50.0 2.7e-72 243.2 34.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Pyr_redox_3 PF13738.1 KPI42856.1 - 2.6e-20 73.3 0.0 9.8e-20 71.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI42856.1 - 7.2e-11 40.9 0.6 4.6e-09 35.0 0.1 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KPI42856.1 - 1e-09 37.8 0.0 2.7e-08 33.1 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KPI42856.1 - 2.1e-07 30.8 0.0 6.8e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI42856.1 - 5.9e-07 29.5 0.0 6.3e-05 22.9 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI42856.1 - 3.4e-05 23.6 0.1 0.0031 17.2 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding p450 PF00067.17 KPI42857.1 - 2.2e-63 214.4 0.0 2.6e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.26 KPI42859.1 - 0.024 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain PRK PF00485.13 KPI42860.1 - 1.4e-05 24.7 0.0 5.4e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.17 KPI42860.1 - 0.00012 21.5 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_17 PF13207.1 KPI42860.1 - 0.0033 18.2 0.0 0.0098 16.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KPI42860.1 - 0.0035 16.4 0.0 0.0066 15.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin ArgK PF03308.11 KPI42860.1 - 0.0039 16.0 0.0 0.0063 15.3 0.0 1.2 1 0 0 1 1 1 1 ArgK protein KAP_NTPase PF07693.9 KPI42860.1 - 0.0085 15.1 0.0 0.0094 14.9 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain NACHT PF05729.7 KPI42860.1 - 0.026 14.1 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 KPI42860.1 - 0.032 13.9 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.12 KPI42860.1 - 0.049 13.0 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase Torsin PF06309.6 KPI42860.1 - 0.06 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_18 PF13238.1 KPI42860.1 - 0.061 13.6 0.1 0.38 11.0 0.0 2.3 3 1 0 3 3 3 0 AAA domain UPF0079 PF02367.12 KPI42860.1 - 0.064 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 LpxK PF02606.9 KPI42860.1 - 0.071 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase cobW PF02492.14 KPI42860.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.15 KPI42860.1 - 0.088 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase CbiA PF01656.18 KPI42860.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cyclase PF04199.8 KPI42861.1 - 1.1e-29 103.3 0.1 1.4e-29 102.9 0.1 1.1 1 0 0 1 1 1 1 Putative cyclase TPT PF03151.11 KPI42862.1 - 3.4e-24 85.2 14.6 3.4e-24 85.2 10.1 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KPI42862.1 - 6.5e-08 31.8 22.1 0.00044 19.2 4.5 2.0 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 KPI42862.1 - 9.1e-06 25.7 34.9 5.2e-05 23.2 9.3 2.5 3 0 0 3 3 3 2 EamA-like transporter family DUF4566 PF15130.1 KPI42863.1 - 0.081 12.0 0.0 0.19 10.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4566) Utp21 PF04192.7 KPI42863.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain DUF4013 PF13197.1 KPI42865.1 - 0.04 13.2 0.0 0.041 13.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) adh_short PF00106.20 KPI42867.1 - 1.2e-62 210.7 7.3 7.3e-32 110.5 0.3 2.6 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 KPI42867.1 - 1.1e-29 103.3 1.8 4.3e-14 52.5 0.0 2.4 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 KPI42867.1 - 2.9e-29 100.9 0.0 7.7e-29 99.5 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain Glucodextran_B PF09136.5 KPI42867.1 - 0.014 15.5 0.1 0.053 13.6 0.1 1.9 1 0 0 1 1 1 0 Glucodextranase, domain B THF_DHG_CYH_C PF02882.14 KPI42867.1 - 0.043 12.8 0.1 0.1 11.7 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SnoaL_3 PF13474.1 KPI42869.1 - 0.0013 18.8 0.2 0.11 12.5 0.2 2.2 1 1 0 1 1 1 1 SnoaL-like domain Imm-NTF2 PF15655.1 KPI42869.1 - 0.0029 18.0 0.2 0.0037 17.7 0.1 1.2 1 0 0 1 1 1 1 NTF2 fold immunity protein SnoaL_4 PF13577.1 KPI42869.1 - 0.0065 16.3 1.5 0.51 10.2 0.2 2.1 1 1 1 2 2 2 2 SnoaL-like domain SnoaL_2 PF12680.2 KPI42869.1 - 0.01 16.2 0.3 0.079 13.3 0.2 1.9 1 1 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.1 KPI42869.1 - 0.012 15.8 0.4 0.033 14.3 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) Tagatose_6_P_K PF08013.6 KPI42869.1 - 0.053 11.9 0.0 0.053 11.9 0.0 1.2 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase MttA_Hcf106 PF02416.11 KPI42870.1 - 0.1 11.7 3.0 0.19 10.8 2.0 1.3 1 0 0 1 1 1 0 mttA/Hcf106 family Methyltransf_16 PF10294.4 KPI42871.1 - 1.2e-16 60.7 0.0 1.9e-15 56.7 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KPI42871.1 - 6.8e-06 25.8 0.0 8.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI42871.1 - 0.00015 22.2 0.0 0.00057 20.4 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI42871.1 - 0.0007 19.6 0.7 0.0032 17.4 0.3 2.2 2 1 0 2 2 2 1 Methyltransferase domain Pro_CA PF00484.14 KPI42872.1 - 5.5e-27 94.6 0.0 7.7e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase COesterase PF00135.23 KPI42873.1 - 4.3e-14 52.1 4.5 1.5e-13 50.3 3.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI42873.1 - 1e-10 41.5 0.2 1.3e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI42873.1 - 4.9e-07 29.6 0.3 7.1e-07 29.0 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI42873.1 - 1.5e-05 24.9 0.1 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KPI42873.1 - 0.0027 16.4 0.0 0.0039 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) PAF-AH_p_II PF03403.8 KPI42873.1 - 0.015 13.5 0.6 0.24 9.6 0.0 2.3 3 0 0 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.2 KPI42873.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Cyt-b5 PF00173.23 KPI42874.1 - 1.1e-10 41.1 0.0 1.4e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Abhydrolase_3 PF07859.8 KPI42875.1 - 1.1e-41 142.7 0.0 1.4e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI42875.1 - 4.5e-06 26.0 0.1 0.00057 19.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 KPI42875.1 - 0.00013 21.2 0.0 0.00071 18.9 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KPI42875.1 - 0.0071 16.1 0.0 0.044 13.5 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KPI42875.1 - 0.052 12.1 0.0 0.086 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) COesterase PF00135.23 KPI42875.1 - 0.1 11.3 0.0 1.1 7.8 0.1 2.0 2 0 0 2 2 2 0 Carboxylesterase family Zn_clus PF00172.13 KPI42876.1 - 0.0021 17.9 8.6 0.0043 16.9 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YlbE PF14003.1 KPI42876.1 - 0.077 13.0 0.4 0.57 10.2 0.0 2.3 2 0 0 2 2 2 0 YlbE-like protein BTB PF00651.26 KPI42877.1 - 0.00066 19.6 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Stn1_C PF12659.2 KPI42877.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH eIF3g PF12353.3 KPI42878.1 - 8.9e-39 132.3 4.8 1.4e-38 131.6 3.3 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 KPI42878.1 - 1.7e-16 59.6 0.1 2.8e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI42878.1 - 3.5e-13 49.3 0.1 6.4e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI42878.1 - 1.4e-07 31.2 0.0 2.6e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATHILA PF03078.10 KPI42878.1 - 0.058 11.9 0.0 0.08 11.5 0.0 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family Abhydrolase_6 PF12697.2 KPI42879.1 - 8.3e-05 22.5 0.6 0.00018 21.4 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI42879.1 - 0.0006 19.5 0.0 0.00072 19.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KPI42879.1 - 0.0016 18.0 0.0 0.0017 17.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI42879.1 - 0.011 14.9 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF900 PF05990.7 KPI42879.1 - 0.15 11.3 0.1 0.38 10.0 0.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Zn_clus PF00172.13 KPI42880.1 - 2e-06 27.5 7.1 4e-06 26.6 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N PF02798.15 KPI42881.1 - 6.8e-15 55.0 0.0 1.5e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KPI42881.1 - 9.9e-13 48.1 0.0 1.8e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KPI42881.1 - 2e-11 43.6 0.0 3.7e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KPI42881.1 - 2.6e-10 40.1 0.0 4.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KPI42881.1 - 1.2e-06 28.3 0.1 2.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KPI42881.1 - 0.00051 20.4 0.0 0.001 19.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HSP9_HSP12 PF04119.7 KPI42882.1 - 3.2e-14 52.7 6.5 5.4e-14 52.0 4.5 1.4 1 0 0 1 1 1 1 Heat shock protein 9/12 PHD PF00628.24 KPI42885.1 - 2e-07 30.5 10.0 3.9e-07 29.6 6.9 1.5 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.10 KPI42885.1 - 0.055 13.1 2.4 0.13 11.9 1.6 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_2 PF13831.1 KPI42885.1 - 0.78 9.1 6.0 1.4 8.2 4.1 1.4 1 0 0 1 1 1 0 PHD-finger BTB PF00651.26 KPI42886.1 - 5.2e-08 32.8 0.1 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain SAC3_GANP PF03399.11 KPI42887.1 - 1.8e-66 223.6 0.3 2.4e-66 223.2 0.2 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KPI42887.1 - 0.00034 20.3 0.2 0.0019 17.9 0.0 2.0 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 DUF155 PF02582.9 KPI42888.1 - 1.9e-59 200.4 0.0 2.6e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 zf-RING_2 PF13639.1 KPI42889.1 - 1.1e-13 50.8 9.2 1.6e-13 50.1 6.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KPI42889.1 - 2.1e-08 34.1 6.0 3.6e-08 33.3 4.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KPI42889.1 - 7.3e-06 25.9 8.5 1.1e-05 25.2 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI42889.1 - 1.6e-05 24.4 9.5 2.5e-05 23.8 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KPI42889.1 - 1.9e-05 24.4 2.0 8.8e-05 22.2 1.4 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KPI42889.1 - 0.00016 21.3 7.7 0.00024 20.7 5.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KPI42889.1 - 0.0025 17.4 5.9 0.0039 16.8 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 KPI42889.1 - 0.0058 16.6 10.4 0.0092 16.0 7.2 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_UBOX PF13445.1 KPI42889.1 - 0.02 14.6 4.6 0.046 13.4 3.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 KPI42889.1 - 0.029 13.8 4.3 0.049 13.1 2.2 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 KPI42889.1 - 0.081 12.8 5.9 0.16 11.9 4.1 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 KPI42889.1 - 1.1 9.2 7.9 1.9 8.5 5.4 1.4 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.1 KPI42889.1 - 3.8 7.3 9.2 1.9 8.2 4.8 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 KPI42889.1 - 9.4 5.9 8.2 23 4.6 5.8 1.6 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Cupin_2 PF07883.6 KPI42890.1 - 8.1e-10 38.0 0.4 8.1e-10 38.0 0.3 2.3 2 1 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 KPI42890.1 - 1.3e-05 24.6 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KPI42890.1 - 0.00023 20.8 0.0 0.00023 20.8 0.0 2.5 2 1 1 3 3 3 1 AraC-like ligand binding domain FdtA PF05523.6 KPI42890.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal GPI PF06560.6 KPI42890.1 - 0.045 12.7 0.0 0.081 11.9 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) JmjC PF02373.17 KPI42890.1 - 0.069 13.3 0.1 0.27 11.4 0.1 2.1 1 1 0 1 1 1 0 JmjC domain, hydroxylase Zip PF02535.17 KPI42890.1 - 8.4 5.2 6.5 11 4.8 4.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Aa_trans PF01490.13 KPI42891.1 - 8.3e-33 113.4 32.0 8.3e-33 113.4 22.2 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein NAD_binding_10 PF13460.1 KPI42892.1 - 9.4e-20 71.3 0.0 1.4e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI42892.1 - 9.4e-17 61.2 0.1 1.4e-16 60.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI42892.1 - 9.1e-16 57.3 0.0 1.4e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KPI42892.1 - 9.3e-16 57.7 0.0 1.2e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KPI42892.1 - 2e-09 36.7 0.0 7.6e-08 31.5 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KPI42892.1 - 3.7e-09 35.8 0.4 6.2e-07 28.5 0.2 2.9 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 KPI42892.1 - 4.8e-08 32.2 0.0 6.8e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KPI42892.1 - 3.6e-06 27.0 0.0 2e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 KPI42892.1 - 9.3e-05 21.5 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 KPI42892.1 - 0.0022 17.7 0.0 0.3 10.7 0.0 2.4 1 1 0 1 1 1 1 KR domain DDE_Tnp_1_3 PF13612.1 KPI42892.1 - 0.035 13.8 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Transposase DDE domain Sds3 PF08598.6 KPI42893.1 - 0.0078 15.7 2.6 0.015 14.8 1.8 1.4 1 0 0 1 1 1 1 Sds3-like TPR_MLP1_2 PF07926.7 KPI42893.1 - 0.018 14.7 5.1 0.028 14.1 3.5 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.17 KPI42893.1 - 0.13 12.2 2.5 0.28 11.2 1.7 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.1 KPI42893.1 - 0.23 10.3 3.8 0.33 9.8 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SCIMP PF15050.1 KPI42893.1 - 4.7 7.1 7.0 0.28 11.0 1.1 1.8 2 0 0 2 2 2 0 SCIMP protein NPL4 PF05021.10 KPI42894.1 - 4.4e-124 413.6 0.0 5.4e-124 413.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KPI42894.1 - 3.5e-72 240.8 0.9 5.2e-72 240.3 0.6 1.2 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region MIP PF00230.15 KPI42894.1 - 0.12 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Major intrinsic protein DUF4451 PF14616.1 KPI42894.1 - 0.83 9.4 3.8 2.9 7.6 2.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) Clr2 PF10383.4 KPI42895.1 - 1.6e-13 50.8 0.0 3.5e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 DHFR_2 PF06442.6 KPI42895.1 - 0.016 14.8 0.4 0.071 12.7 0.0 2.1 2 0 0 2 2 2 0 R67 dihydrofolate reductase MFS_1 PF07690.11 KPI42897.1 - 1.9e-33 115.6 38.1 1.9e-33 115.6 26.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.17 KPI42898.1 - 1.6e-153 511.4 0.4 3.5e-153 510.2 0.1 1.6 2 0 0 2 2 2 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KPI42898.1 - 0.00013 21.2 0.0 0.058 12.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.9 KPI42898.1 - 0.00087 18.1 0.6 0.0021 16.8 0.4 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Dicty_REP PF05086.7 KPI42899.1 - 0.51 8.0 5.7 0.67 7.6 4.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ras PF00071.17 KPI42900.1 - 3.1e-54 182.7 0.0 3.6e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KPI42900.1 - 5.8e-17 62.2 0.0 7.9e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KPI42900.1 - 1.4e-08 34.2 0.0 2.3e-08 33.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KPI42900.1 - 0.00074 18.7 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KPI42900.1 - 0.021 14.0 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KPI42900.1 - 0.021 13.5 0.0 0.033 12.8 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit Arch_ATPase PF01637.13 KPI42900.1 - 0.05 13.3 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 KPI42900.1 - 0.069 13.1 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 KPI42900.1 - 0.099 12.1 0.0 1.5 8.3 0.0 2.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation CN_hydrolase PF00795.17 KPI42901.1 - 3.5e-30 104.7 0.0 9e-30 103.4 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase ATP-synt_G PF04718.10 KPI42902.1 - 9.6e-11 42.2 0.1 4.1e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit EspB PF05802.6 KPI42902.1 - 0.3 10.0 4.9 0.44 9.4 3.4 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein Epiglycanin_TR PF05647.6 KPI42902.1 - 0.61 9.9 13.6 1 9.2 9.4 1.3 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like ACPS PF01648.15 KPI42904.1 - 4.2e-15 55.5 0.0 1.3e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily SH3_1 PF00018.23 KPI42905.1 - 2.2e-24 84.5 0.0 4.3e-11 42.0 0.0 2.9 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 KPI42905.1 - 8.4e-15 54.0 1.1 1.8e-06 27.4 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 KPI42905.1 - 3.4e-12 45.6 0.0 7.7e-08 31.7 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 KPI42905.1 - 2.2e-10 40.3 0.0 4.8e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 KPI42905.1 - 1.4e-08 34.2 0.0 2.4e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 PB1 domain RRM_1 PF00076.17 KPI42906.1 - 7.1e-73 240.2 0.0 2.9e-20 71.6 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI42906.1 - 7.1e-61 202.1 0.2 1.2e-14 54.0 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI42906.1 - 1.8e-29 101.3 0.0 8e-08 32.0 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KPI42906.1 - 0.15 11.8 0.0 10 5.9 0.0 2.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF2611 PF11022.3 KPI42907.1 - 4.5e-23 81.1 0.0 5e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) MFS_1 PF07690.11 KPI42908.1 - 3.1e-21 75.4 34.7 3.1e-21 75.4 24.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily GMC_oxred_N PF00732.14 KPI42910.1 - 6.3e-59 199.5 0.0 8.1e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI42910.1 - 1.8e-29 102.8 0.1 3.6e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KPI42910.1 - 1.3e-05 24.2 0.2 0.001 18.0 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KPI42910.1 - 2.9e-05 23.1 0.3 5.5e-05 22.2 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KPI42910.1 - 0.00028 19.8 0.8 0.0014 17.5 0.6 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KPI42910.1 - 0.0011 18.9 0.3 0.0032 17.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI42910.1 - 0.0049 16.7 0.1 0.063 13.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI42910.1 - 0.007 15.4 0.2 0.038 13.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family BTB PF00651.26 KPI42912.1 - 0.0025 17.7 0.0 0.0054 16.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain SLR1-BP PF07333.7 KPI42912.1 - 0.67 10.2 5.4 2.1 8.6 3.7 1.9 1 1 0 1 1 1 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Umbravirus_LDM PF04817.7 KPI42914.1 - 0.043 12.9 0.6 6.4 5.8 0.1 2.4 2 0 0 2 2 2 0 Umbravirus long distance movement (LDM) family GFA PF04828.9 KPI42915.1 - 1.2e-19 70.0 2.8 1.8e-19 69.4 1.9 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ADH_zinc_N PF00107.21 KPI42916.1 - 2.4e-14 53.0 0.0 3.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pam16 PF03656.8 KPI42917.1 - 3.8e-33 113.9 0.2 4.4e-33 113.7 0.2 1.0 1 0 0 1 1 1 1 Pam16 PHO4 PF01384.15 KPI42918.1 - 4.7e-78 262.0 8.6 6e-78 261.7 6.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family Tmemb_185A PF10269.4 KPI42918.1 - 0.018 14.6 0.7 0.04 13.5 0.5 1.5 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein Glycophorin_A PF01102.13 KPI42918.1 - 0.057 13.1 0.2 0.17 11.6 0.2 1.7 1 0 0 1 1 1 0 Glycophorin A Podoplanin PF05808.6 KPI42918.1 - 0.49 9.9 5.3 0.68 9.4 0.1 3.0 3 0 0 3 3 3 0 Podoplanin Adeno_E3_CR2 PF02439.10 KPI42918.1 - 4.3 6.9 5.8 0.6 9.7 0.4 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF2417 PF10329.4 KPI42919.1 - 2.8e-84 282.1 0.2 3.9e-84 281.6 0.1 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 KPI42919.1 - 1.3e-09 38.2 0.1 2.6e-09 37.3 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF3357 PF11837.3 KPI42919.1 - 0.21 11.4 2.7 0.35 10.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) RCR PF12273.3 KPI42919.1 - 0.56 10.7 0.0 0.56 10.7 0.0 2.7 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red ABC2_membrane_3 PF12698.2 KPI42919.1 - 7.8 5.4 15.6 11 4.8 10.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein CHD5 PF04420.9 KPI42920.1 - 8e-46 155.6 0.0 1.1e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 CHD5-like protein RGS PF00615.14 KPI42921.1 - 5.2e-13 49.1 0.0 1.4e-09 38.0 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain XendoU PF09412.5 KPI42921.1 - 0.042 12.8 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Endoribonuclease XendoU Aa_trans PF01490.13 KPI42922.1 - 1.9e-61 207.7 16.7 2.6e-61 207.3 11.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PAN_1 PF00024.21 KPI42922.1 - 7.2e-10 38.4 14.5 0.00014 21.5 2.1 3.5 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.1 KPI42922.1 - 0.2 11.4 19.4 0.33 10.7 1.1 4.6 3 1 0 3 3 3 0 PAN domain PAN_3 PF08277.7 KPI42922.1 - 0.77 9.4 7.7 7.3 6.2 0.3 3.5 3 0 0 3 3 3 0 PAN-like domain MANEC PF07502.9 KPI42922.1 - 9.3 6.3 12.7 0.2 11.6 1.2 2.9 3 0 0 3 3 3 0 MANEC domain XPG_I PF00867.13 KPI42923.1 - 8.7e-23 80.2 0.0 2e-22 79.0 0.0 1.6 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 KPI42923.1 - 4.7e-05 23.5 0.0 9.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain PIG-H PF10181.4 KPI42925.1 - 1.6e-24 85.2 0.6 2.7e-24 84.5 0.4 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component ADH_N PF08240.7 KPI42926.1 - 5.4e-22 77.6 0.3 7.1e-22 77.2 0.2 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ribosomal_L22 PF00237.14 KPI42927.1 - 1.7e-36 124.3 0.1 2.3e-36 123.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e ATP_bind_1 PF03029.12 KPI42928.1 - 2.8e-76 256.2 0.0 3.8e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 KPI42928.1 - 9.4e-06 24.5 0.0 0.0034 16.1 0.0 2.3 2 0 0 2 2 2 2 ArgK protein GTP_EFTU PF00009.22 KPI42928.1 - 3.2e-05 23.4 0.0 0.0028 17.0 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KPI42928.1 - 0.00018 21.6 0.0 0.00063 19.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KPI42928.1 - 0.0004 20.3 0.0 0.0017 18.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase NB-ARC PF00931.17 KPI42928.1 - 0.00084 18.2 0.3 0.0047 15.8 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.1 KPI42928.1 - 0.0013 18.6 0.3 0.0037 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KPI42928.1 - 0.0018 17.9 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KPI42928.1 - 0.0019 17.3 0.0 0.0069 15.5 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin SRP54 PF00448.17 KPI42928.1 - 0.0025 17.3 0.0 0.0067 15.8 0.0 1.7 2 0 0 2 2 1 1 SRP54-type protein, GTPase domain AAA_17 PF13207.1 KPI42928.1 - 0.0032 18.2 3.5 0.005 17.6 0.0 2.4 2 1 0 2 2 1 1 AAA domain NACHT PF05729.7 KPI42928.1 - 0.0037 16.9 0.0 0.015 14.9 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 KPI42928.1 - 0.0047 16.4 0.4 0.012 15.1 0.2 2.0 1 1 0 1 1 1 1 AAA-like domain FeoB_N PF02421.13 KPI42928.1 - 0.0058 15.9 0.0 0.15 11.2 0.0 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B Miro PF08477.8 KPI42928.1 - 0.0062 17.0 0.0 5.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 KPI42928.1 - 0.0081 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 KPI42928.1 - 0.0083 15.7 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KPI42928.1 - 0.011 15.2 0.2 0.075 12.5 0.0 2.4 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.13 KPI42928.1 - 0.013 15.0 0.0 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Thymidylate_kin PF02223.12 KPI42928.1 - 0.014 14.7 1.5 0.95 8.8 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase Arf PF00025.16 KPI42928.1 - 0.015 14.5 0.0 3 7.0 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family cobW PF02492.14 KPI42928.1 - 0.041 13.3 0.1 0.64 9.4 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 KPI42928.1 - 0.078 11.9 0.0 0.2 10.6 0.0 1.7 2 0 0 2 2 2 0 KAP family P-loop domain AAA_24 PF13479.1 KPI42928.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KPI42928.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase G-alpha PF00503.15 KPI42928.1 - 0.14 10.8 2.3 3.4 6.2 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit CHZ PF09649.5 KPI42929.1 - 6.6e-05 22.0 1.2 0.00015 20.9 0.8 1.6 1 0 0 1 1 1 1 Histone chaperone domain CHZ F-box-like_2 PF13013.1 KPI42930.1 - 0.016 14.9 0.1 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 F-box-like domain DUF2945 PF11160.3 KPI42931.1 - 0.0052 16.5 1.9 0.0052 16.5 1.3 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2945) DUF1860 PF08949.5 KPI42931.1 - 0.11 12.0 1.0 0.16 11.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) Nop14 PF04147.7 KPI42931.1 - 3.4 5.4 26.5 3.7 5.3 18.4 1.1 1 0 0 1 1 1 0 Nop14-like family Fasciclin PF02469.17 KPI42932.1 - 1.5e-18 67.0 0.2 8.9e-09 35.4 0.0 2.3 2 1 0 2 2 2 2 Fasciclin domain XPC-binding PF09280.6 KPI42932.1 - 0.1 12.0 0.0 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 XPC-binding domain FAD_binding_3 PF01494.14 KPI42934.1 - 2.7e-18 66.1 0.0 4.3e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KPI42934.1 - 7.1e-05 22.6 2.0 0.0027 17.5 0.1 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KPI42934.1 - 0.0016 18.4 1.0 0.0024 17.8 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KPI42934.1 - 0.0017 16.9 0.2 0.027 12.9 0.1 2.3 1 1 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 KPI42934.1 - 0.0049 15.5 0.1 0.027 13.1 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.19 KPI42934.1 - 0.014 14.3 0.3 0.47 9.2 0.2 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.5 KPI42934.1 - 0.024 13.4 0.0 0.097 11.4 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase FAD_binding_2 PF00890.19 KPI42934.1 - 0.04 12.7 0.0 0.07 11.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KPI42934.1 - 0.066 13.0 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase OTT_1508_deam PF14441.1 KPI42935.1 - 4.3e-09 36.3 0.0 9.2e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase WSC PF01822.14 KPI42936.1 - 1.3e-13 50.7 12.1 2.4e-13 49.7 8.4 1.5 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.5 KPI42936.1 - 3.8e-05 22.8 3.8 3.8e-05 22.8 2.6 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 KPI42936.1 - 0.0041 15.4 0.0 0.0054 15.0 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF4501 PF14946.1 KPI42936.1 - 0.0042 16.5 0.1 0.0082 15.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4501) MLANA PF14991.1 KPI42936.1 - 0.011 15.7 0.2 0.31 11.0 0.0 2.7 2 1 0 3 3 3 0 Protein melan-A DUF1191 PF06697.7 KPI42936.1 - 0.012 14.4 0.1 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4448 PF14610.1 KPI42936.1 - 0.025 14.0 0.0 0.053 13.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF4366 PF14283.1 KPI42936.1 - 0.055 12.8 0.3 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) EphA2_TM PF14575.1 KPI42936.1 - 0.083 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.1 KPI42936.1 - 0.12 10.8 0.0 0.32 9.4 0.0 1.6 2 0 0 2 2 2 0 Amnionless DUF4231 PF14015.1 KPI42936.1 - 1.3 8.9 4.0 2.8 7.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) UCH PF00443.24 KPI42937.1 - 1.6e-42 145.4 0.1 1.5e-41 142.2 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KPI42937.1 - 4.9e-11 42.6 2.4 4.1e-10 39.5 1.7 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_RNApol_7kD PF03604.8 KPI42937.1 - 1 8.9 4.8 0.24 10.8 0.3 2.0 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-H2C2_5 PF13909.1 KPI42937.1 - 4 7.8 5.6 1.7 8.9 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Methyltransf_23 PF13489.1 KPI42938.1 - 4.1e-21 75.3 0.0 6.1e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI42938.1 - 8.7e-10 38.3 0.0 7.6e-09 35.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI42938.1 - 2.2e-09 37.8 0.1 3.1e-08 34.1 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI42938.1 - 1.8e-08 34.7 0.0 4.6e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI42938.1 - 6.2e-08 33.0 0.0 4.3e-07 30.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KPI42938.1 - 0.00019 20.5 0.0 0.00056 19.0 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KPI42938.1 - 0.00058 19.2 0.0 0.018 14.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 KPI42938.1 - 0.00063 18.9 0.0 0.0031 16.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 KPI42938.1 - 0.0023 18.2 0.0 0.0083 16.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI42938.1 - 0.013 15.5 0.0 0.14 12.2 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 KPI42938.1 - 0.024 14.0 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 KPI42938.1 - 0.047 12.7 0.0 0.34 10.0 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KPI42938.1 - 0.092 11.8 0.0 0.16 11.0 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 KPI42938.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 KPI42938.1 - 0.15 11.1 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Peptidase_S8 PF00082.17 KPI42939.1 - 7.7e-44 149.9 0.8 1.5e-43 149.0 0.6 1.4 1 0 0 1 1 1 1 Subtilase family Grp1_Fun34_YaaH PF01184.14 KPI42940.1 - 2.1e-24 85.9 19.9 2.8e-24 85.5 13.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3671 PF12420.3 KPI42940.1 - 4.1 7.4 6.6 3.3 7.7 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function TBCC PF07986.7 KPI42941.1 - 4.6e-26 90.5 6.7 4.9e-26 90.4 3.1 2.2 1 1 1 2 2 2 1 Tubulin binding cofactor C IBR PF01485.16 KPI42942.1 - 5.1e-07 29.4 3.1 5.1e-07 29.4 2.2 4.7 4 2 0 4 4 4 2 IBR domain UPF0547 PF10571.4 KPI42942.1 - 0.045 13.4 5.2 1.8 8.3 0.0 3.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 CUE PF02845.11 KPI42942.1 - 0.049 13.1 0.2 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 CUE domain Yip1 PF04893.12 KPI42943.1 - 4.8e-10 39.2 14.1 8.5e-10 38.3 9.8 1.4 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 KPI42943.1 - 0.023 14.3 5.8 0.036 13.7 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) zf-CCCH PF00642.19 KPI42944.1 - 9.5e-11 41.1 11.9 6.6e-06 25.6 1.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KPI42944.1 - 1.7 8.7 15.9 5.1 7.2 3.0 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Con-6 PF10346.4 KPI42945.1 - 9.3e-12 44.1 0.3 1.4e-11 43.5 0.2 1.3 1 0 0 1 1 1 1 Conidiation protein 6 SpoIIIAH PF12685.2 KPI42945.1 - 0.019 14.4 0.2 0.026 14.0 0.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein GDI PF00996.13 KPI42946.1 - 2.5e-178 592.9 0.0 2.9e-178 592.7 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 KPI42946.1 - 0.022 14.7 0.1 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KPI42946.1 - 0.11 12.9 0.3 0.64 10.4 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Rad1 PF02144.11 KPI42947.1 - 1.3e-71 240.6 0.0 1.5e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 BTB PF00651.26 KPI42948.1 - 4.9e-11 42.5 0.4 1.1e-10 41.4 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.10 KPI42948.1 - 0.00019 21.4 0.0 0.00037 20.5 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain RICTOR_M PF14666.1 KPI42948.1 - 0.0068 15.4 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, middle domain Ribosomal_S2 PF00318.15 KPI42949.1 - 1.4e-43 148.6 0.0 5.5e-23 81.2 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Aldedh PF00171.17 KPI42951.1 - 8.4e-75 251.8 0.0 1.1e-74 251.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.11 KPI42952.1 - 1.6e-28 99.4 60.9 9e-22 77.2 20.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KPI42952.1 - 0.00039 20.1 5.6 0.00042 20.0 0.6 3.0 3 0 0 3 3 3 1 MFS_1 like family CALCOCO1 PF07888.6 KPI42953.1 - 0.37 9.0 10.8 0.68 8.1 7.5 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF724 PF05266.9 KPI42953.1 - 0.38 10.3 10.1 0.1 12.2 3.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.14 KPI42953.1 - 0.84 7.4 4.6 1.4 6.6 3.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMCO5 PF14992.1 KPI42953.1 - 1.9 7.5 15.4 1.6 7.7 8.3 2.0 2 0 0 2 2 2 0 TMCO5 family FUSC PF04632.7 KPI42953.1 - 4.2 5.6 6.8 4.8 5.4 1.8 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family KxDL PF10241.4 KPI42953.1 - 5.8 6.8 12.0 16 5.4 0.2 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein COesterase PF00135.23 KPI42954.1 - 4.9e-91 306.0 0.2 6.5e-91 305.6 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI42954.1 - 1.3e-07 31.3 0.0 1.9e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI42954.1 - 0.002 17.3 0.2 0.0031 16.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PCI PF01399.22 KPI42957.1 - 0.00071 19.8 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 PCI domain SnoaL_2 PF12680.2 KPI42958.1 - 0.004 17.5 0.1 0.0053 17.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Abhydrolase_6 PF12697.2 KPI42959.1 - 5.8e-05 23.0 0.0 7.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Acyl_transf_3 PF01757.17 KPI42960.1 - 0.00022 20.1 15.0 0.039 12.7 6.0 2.3 2 0 0 2 2 2 2 Acyltransferase family Ribosomal_L6 PF00347.18 KPI42961.1 - 2.6e-24 85.4 11.3 2.4e-12 47.1 2.9 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 DUF2292 PF10055.4 KPI42961.1 - 0.098 12.0 0.9 0.27 10.6 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2292) MTP18 PF10558.4 KPI42962.1 - 2.1e-67 225.6 0.1 2.7e-67 225.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Glyco_hydro_18 PF00704.23 KPI42964.1 - 1.9e-11 44.0 0.0 3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Abhydrolase_6 PF12697.2 KPI42965.1 - 1.1e-21 77.8 1.4 1.4e-21 77.4 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI42965.1 - 1.8e-09 37.4 0.0 3.5e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KPI42965.1 - 0.031 13.8 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.7 KPI42965.1 - 0.053 13.0 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_1 PF00561.15 KPI42965.1 - 0.079 12.4 0.0 0.15 11.5 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Glyco_hydro_17 PF00332.13 KPI42966.1 - 2.2e-05 23.6 0.1 3.5e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Pyridox_oxidase PF01243.15 KPI42967.1 - 4.4e-09 36.2 0.0 1.2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.1 KPI42967.1 - 0.003 17.3 0.4 0.0044 16.7 0.3 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 KPI42967.1 - 0.099 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Asp PF00026.18 KPI42968.1 - 1.6e-68 231.3 5.8 1.6e-68 231.3 4.0 1.6 2 0 0 2 2 2 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KPI42968.1 - 4.6e-07 30.2 0.4 0.013 15.9 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease TAXi_N PF14543.1 KPI42968.1 - 7.3e-07 29.2 0.1 7.3e-07 29.2 0.1 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KPI42968.1 - 0.00055 19.5 0.0 0.016 14.7 0.0 2.6 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KPI42968.1 - 0.0026 17.5 0.0 0.73 9.7 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease SCIMP PF15050.1 KPI42969.1 - 0.0093 15.8 2.5 0.014 15.3 0.6 2.1 1 1 0 1 1 1 1 SCIMP protein Macoilin PF09726.4 KPI42969.1 - 2.7 6.1 10.3 3.3 5.8 7.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_S15 PF00312.17 KPI42970.1 - 6.1e-07 29.1 0.2 1.1e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 U1snRNP70_N PF12220.3 KPI42970.1 - 0.11 12.8 1.9 0.15 12.3 0.2 2.0 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal HSF_DNA-bind PF00447.12 KPI42971.1 - 2.5e-36 123.9 1.3 3.6e-36 123.4 0.9 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding IncA PF04156.9 KPI42971.1 - 0.082 12.4 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 IncA protein EzrA PF06160.7 KPI42971.1 - 0.31 9.1 0.0 0.44 8.6 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Chisel PF15355.1 KPI42972.1 - 0.027 14.4 0.2 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 Stretch-responsive small skeletal muscle X protein, Chisel YEATS PF03366.11 KPI42972.1 - 0.044 13.4 0.1 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 YEATS family DUF427 PF04248.7 KPI42973.1 - 1.1e-17 63.4 0.2 1.4e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) AFG1_ATPase PF03969.11 KPI42976.1 - 6.1e-98 327.9 0.1 1.3e-92 310.4 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase Bac_DnaA PF00308.13 KPI42976.1 - 0.00066 19.3 0.2 0.11 12.1 0.0 2.5 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_16 PF13191.1 KPI42976.1 - 0.0011 19.0 0.1 0.6 10.0 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 KPI42976.1 - 0.0015 18.4 0.0 0.004 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KPI42976.1 - 0.037 14.2 0.0 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KPI42976.1 - 0.039 14.1 0.0 0.13 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KPI42976.1 - 0.066 13.3 0.0 0.21 11.7 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 KPI42976.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Abhydrolase_6 PF12697.2 KPI42977.1 - 1.2e-24 87.4 1.1 4.1e-24 85.7 0.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI42977.1 - 1.8e-12 47.3 0.3 3.3e-09 36.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI42977.1 - 2.6e-11 43.4 0.0 3.5e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KPI42977.1 - 6.2e-05 23.3 0.3 0.0011 19.2 0.2 2.1 1 1 0 1 1 1 1 Thioesterase domain Ndr PF03096.9 KPI42977.1 - 0.00085 17.8 0.0 0.0013 17.3 0.0 1.3 1 0 0 1 1 1 1 Ndr family PGAP1 PF07819.8 KPI42977.1 - 0.00089 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 KPI42977.1 - 0.0009 18.8 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 KPI42977.1 - 0.003 16.8 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Ser_hydrolase PF06821.8 KPI42977.1 - 0.042 13.4 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase DUF2305 PF10230.4 KPI42977.1 - 0.076 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 KPI42977.1 - 0.11 11.8 0.1 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) LamB PF02264.10 KPI42977.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 LamB porin Sugar_tr PF00083.19 KPI42979.1 - 9.6e-83 278.2 16.9 1.1e-82 278.0 11.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI42979.1 - 1e-13 50.7 27.2 7.7e-12 44.5 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_9 PF13371.1 KPI42979.1 - 0.02 14.7 0.1 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF485 PF04341.7 KPI42979.1 - 0.23 11.1 7.8 1.6 8.4 0.6 2.8 1 1 1 2 2 2 0 Protein of unknown function, DUF485 GST_N_3 PF13417.1 KPI42980.1 - 1e-07 32.0 0.0 1.9e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI42980.1 - 2.6e-05 24.1 0.0 5.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KPI42980.1 - 4.7e-05 23.8 0.0 8.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI42980.1 - 0.00029 20.6 0.0 0.00063 19.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KPI42980.1 - 0.026 14.5 0.1 0.075 13.0 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KPI42980.1 - 0.037 14.2 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KPI42981.1 - 1.5e-11 44.3 0.0 3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI42981.1 - 5e-10 39.2 0.0 8.9e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KPI42981.1 - 8.2e-09 35.5 0.0 1.4e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KPI42981.1 - 1.5e-08 34.5 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KPI42981.1 - 2.5e-05 24.6 0.0 3.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI42981.1 - 0.036 13.9 0.1 0.055 13.3 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Csm1 PF12539.3 KPI42982.1 - 5.3e-23 81.3 0.1 1.3e-22 80.0 0.1 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 USP8_interact PF08941.5 KPI42982.1 - 0.012 14.9 0.2 0.03 13.6 0.1 1.7 1 0 0 1 1 1 0 USP8 interacting APG6 PF04111.7 KPI42982.1 - 0.035 13.1 8.6 0.077 12.0 6.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Reo_sigmaC PF04582.7 KPI42982.1 - 0.076 12.1 4.6 0.13 11.4 3.2 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 KPI42982.1 - 0.32 10.7 11.8 0.042 13.5 3.8 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding CCDC-167 PF15188.1 KPI42982.1 - 0.38 10.7 5.6 1.7 8.6 3.7 2.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 IncA PF04156.9 KPI42982.1 - 2.5 7.6 11.5 9.6 5.7 7.7 1.8 1 1 0 1 1 1 0 IncA protein GAS PF13851.1 KPI42982.1 - 3.8 6.6 17.4 0.44 9.7 7.8 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 KPI42982.1 - 4.8 7.0 7.5 0.91 9.3 2.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_L6e PF01159.14 KPI42983.1 - 1.1e-39 134.9 0.5 1.1e-39 134.9 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L6e COG6 PF06419.6 KPI42984.1 - 3.1e-157 524.4 0.2 3.9e-157 524.0 0.1 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Exo70 PF03081.10 KPI42984.1 - 0.00022 20.1 0.2 0.0027 16.5 0.0 2.3 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Kinase-PPPase PF03618.9 KPI42984.1 - 0.083 12.3 0.1 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinase/pyrophosphorylase Abhydrolase_6 PF12697.2 KPI42985.1 - 0.00017 21.5 0.2 0.00033 20.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KPI42985.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase PI3_PI4_kinase PF00454.22 KPI42986.1 - 1.8e-46 158.5 0.0 4.9e-46 157.0 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KPI42986.1 - 5.3e-39 134.2 3.6 1.3e-38 132.9 2.5 1.7 1 0 0 1 1 1 1 FAT domain UME PF08064.8 KPI42986.1 - 7.6e-26 90.1 0.2 4.7e-25 87.6 0.0 2.5 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 KPI42986.1 - 2.1e-11 43.0 0.9 5.1e-11 41.8 0.0 2.2 2 0 0 2 2 2 1 FATC domain TPR_14 PF13428.1 KPI42986.1 - 0.0069 16.9 1.0 7.2 7.5 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KPI42986.1 - 0.11 12.8 2.6 7.1 7.0 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Cas_TM1802 PF09484.5 KPI42986.1 - 2.3 6.5 3.5 1.5 7.1 0.1 2.2 2 0 0 2 2 2 0 CRISPR-associated protein TM1802 (cas_TM1802) SMK-1 PF04802.10 KPI42987.1 - 5e-74 248.0 0.8 5e-74 248.0 0.6 1.9 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 DUF3602 PF12223.3 KPI42988.1 - 3.2e-20 72.2 14.7 5.3e-16 58.7 1.0 2.7 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DUF3210 PF11489.3 KPI42989.1 - 2.7e-178 594.9 63.5 2.7e-178 594.9 44.0 3.9 3 1 0 3 3 3 1 Protein of unknown function (DUF3210) ATG2_CAD PF13329.1 KPI42989.1 - 4.6e-31 107.5 0.0 1.1e-30 106.3 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 KPI42989.1 - 2.6e-27 94.8 0.1 7.1e-27 93.4 0.1 1.9 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 KPI42989.1 - 0.00093 18.7 0.0 0.0058 16.1 0.0 2.3 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter RNA_pol_Rpb4 PF03874.11 KPI42990.1 - 2.6e-08 33.8 0.1 0.0001 22.2 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase Rpb4 MMPL PF03176.10 KPI42990.1 - 0.19 10.3 0.9 0.29 9.7 0.6 1.2 1 0 0 1 1 1 0 MMPL family PseudoU_synth_1 PF01416.15 KPI42991.1 - 4.4e-24 84.9 0.0 5.5e-19 68.5 0.0 3.3 2 1 0 2 2 2 2 tRNA pseudouridine synthase Med12 PF09497.5 KPI42992.1 - 1.1e-22 79.7 0.1 3.7e-22 78.0 0.1 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 AAA PF00004.24 KPI42993.1 - 9.5e-37 126.1 0.0 2.4e-36 124.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KPI42993.1 - 3.7e-06 26.8 0.0 8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KPI42993.1 - 4.4e-06 26.8 0.2 0.00065 19.7 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KPI42993.1 - 6.1e-06 25.4 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KPI42993.1 - 1.9e-05 24.3 0.0 0.00014 21.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KPI42993.1 - 2.8e-05 24.2 0.1 0.00078 19.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KPI42993.1 - 5.5e-05 23.9 0.1 0.00016 22.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 KPI42993.1 - 0.00012 21.5 0.3 0.028 13.8 0.1 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KPI42993.1 - 0.00018 20.9 0.0 0.00046 19.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 KPI42993.1 - 0.00019 21.3 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KPI42993.1 - 0.00025 20.9 0.0 0.00055 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KPI42993.1 - 0.00082 18.5 0.1 0.0017 17.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KPI42993.1 - 0.00085 19.4 0.0 0.0025 17.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Sigma54_activ_2 PF14532.1 KPI42993.1 - 0.0013 18.7 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_11 PF13086.1 KPI42993.1 - 0.0016 18.1 0.2 0.0034 17.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KPI42993.1 - 0.0022 17.9 0.2 0.0056 16.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 KPI42993.1 - 0.0034 17.0 0.2 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 KPI42993.1 - 0.0037 16.7 0.6 1.7 7.9 0.0 3.2 3 1 0 3 3 3 1 AAA-like domain AAA_19 PF13245.1 KPI42993.1 - 0.0042 16.7 0.1 0.024 14.3 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 KPI42993.1 - 0.0043 17.3 0.2 0.016 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KPI42993.1 - 0.0049 15.9 0.0 0.0091 15.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.1 KPI42993.1 - 0.0071 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KPI42993.1 - 0.019 14.4 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KPI42993.1 - 0.019 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CPT PF07931.7 KPI42993.1 - 0.028 14.0 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 KPI42993.1 - 0.032 14.5 0.0 0.069 13.4 0.0 1.8 1 1 0 1 1 1 0 ABC transporter DUF815 PF05673.8 KPI42993.1 - 0.033 13.1 0.0 0.063 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 KPI42993.1 - 0.048 13.3 0.0 0.25 10.9 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase Bac_DnaA PF00308.13 KPI42993.1 - 0.067 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Viral_helicase1 PF01443.13 KPI42993.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 KPI42993.1 - 0.073 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SKI PF01202.17 KPI42993.1 - 0.095 12.5 0.4 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 Shikimate kinase NB-ARC PF00931.17 KPI42993.1 - 0.11 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2721 PF11026.3 KPI42994.1 - 0.14 11.7 1.5 0.27 10.8 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Ribosomal_L31e PF01198.14 KPI42995.1 - 7.6e-20 70.3 1.6 1.1e-19 69.8 0.1 1.9 1 1 1 2 2 2 1 Ribosomal protein L31e Beta-lactamase PF00144.19 KPI42997.1 - 5.6e-38 130.7 0.0 1e-37 129.9 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KPI42997.1 - 0.009 15.3 0.2 0.017 14.3 0.1 1.5 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase JAB PF01398.16 KPI42998.1 - 8.4e-15 54.5 0.0 2.8e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 KPI42998.1 - 1.5e-08 34.5 0.1 2.7e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 KPI42998.1 - 3.8e-07 29.6 0.1 1.5e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain DUF4011 PF13195.1 KPI42998.1 - 4 7.4 8.1 54 3.7 6.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4011) E1-E2_ATPase PF00122.15 KPI43000.1 - 1.2e-66 224.0 3.8 2.1e-66 223.2 2.6 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KPI43000.1 - 2.6e-32 112.9 0.0 1.4e-30 107.3 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KPI43000.1 - 7.6e-30 103.7 8.3 7.6e-30 103.7 5.7 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KPI43000.1 - 8.4e-20 70.5 0.0 1.5e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KPI43000.1 - 6.9e-15 55.7 0.0 1.8e-14 54.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KPI43000.1 - 1.9e-14 52.8 0.1 7.4e-14 50.9 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KPI43000.1 - 1.1e-05 25.1 1.0 0.0025 17.4 1.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase KR PF08659.5 KPI43000.1 - 0.04 13.5 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 KR domain CoA_binding_3 PF13727.1 KPI43000.1 - 3.8 7.3 10.0 2 8.2 1.5 3.7 3 0 0 3 3 3 0 CoA-binding domain Clr5 PF14420.1 KPI43001.1 - 9.7e-17 60.6 1.2 2.5e-16 59.3 0.8 1.7 1 0 0 1 1 1 1 Clr5 domain Ank_2 PF12796.2 KPI43003.1 - 4.7e-28 97.3 0.6 1.1e-13 51.2 0.2 3.2 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KPI43003.1 - 1.9e-22 77.8 5.8 7.8e-08 31.7 0.3 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 KPI43003.1 - 7.2e-21 74.1 1.2 3.4e-07 30.5 0.0 4.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KPI43003.1 - 1e-18 66.8 4.3 1.9e-05 24.7 0.0 4.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI43003.1 - 5.7e-18 63.2 0.1 0.0012 18.9 0.1 5.9 6 0 0 6 6 6 3 Ankyrin repeat SAP PF02037.22 KPI43004.1 - 4.8e-08 32.3 0.0 9.7e-08 31.3 0.0 1.6 1 0 0 1 1 1 1 SAP domain Methyltransf_2 PF00891.13 KPI43005.1 - 2.3e-31 108.8 0.0 3.3e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KPI43005.1 - 0.041 13.7 0.2 0.13 12.1 0.1 1.9 1 0 0 1 1 1 0 Dimerisation domain Rrf2 PF02082.15 KPI43005.1 - 0.047 13.8 0.1 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator Pyr_redox_3 PF13738.1 KPI43006.1 - 7e-13 49.1 0.0 1.3e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI43006.1 - 5.5e-10 39.1 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KPI43006.1 - 1.5e-09 36.6 1.3 2.4e-08 32.6 0.1 2.7 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 KPI43006.1 - 0.0015 18.3 0.0 0.033 13.9 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KPI43006.1 - 0.017 14.0 0.0 0.59 8.9 0.0 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 KPI43006.1 - 0.083 11.9 0.0 0.66 9.0 0.0 2.2 3 0 0 3 3 3 0 Thi4 family zf-CCCH PF00642.19 KPI43007.1 - 0.5 10.1 4.4 0.97 9.1 3.1 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FAM196 PF15265.1 KPI43009.1 - 0.0062 15.8 16.5 0.0076 15.5 11.4 1.1 1 0 0 1 1 1 1 FAM196 family DUF3460 PF11943.3 KPI43009.1 - 0.75 9.9 6.2 9 6.4 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3460) EthD PF07110.6 KPI43011.1 - 3.1e-21 76.1 0.2 3.6e-21 75.8 0.1 1.1 1 0 0 1 1 1 1 EthD domain TAF PF02969.12 KPI43011.1 - 0.08 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) AT_hook PF02178.14 KPI43013.1 - 0.9 9.4 7.6 2.9 7.8 5.3 1.9 1 0 0 1 1 1 0 AT hook motif Ran_BP1 PF00638.13 KPI43015.1 - 4.5e-20 71.9 0.2 4.6e-11 42.8 0.2 2.3 2 0 0 2 2 2 2 RanBP1 domain CwfJ_C_1 PF04677.10 KPI43016.1 - 2.4e-26 91.7 0.0 4e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KPI43016.1 - 3.3e-24 85.2 0.1 9.3e-24 83.7 0.0 1.8 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 GST_N_3 PF13417.1 KPI43016.1 - 1.2e-09 38.2 0.0 7.4e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI43016.1 - 2.2e-07 30.7 0.0 5.3e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain A_deaminase_N PF08451.6 KPI43016.1 - 0.15 12.0 0.7 0.58 10.2 0.0 2.3 2 0 0 2 2 2 0 Adenosine/AMP deaminase N-terminal Lactonase PF10282.4 KPI43017.1 - 2.7e-25 89.1 0.2 1.3e-24 86.9 0.1 2.0 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.7 KPI43017.1 - 0.029 13.7 0.0 0.17 11.1 0.0 2.2 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region SWIRM PF04433.12 KPI43018.1 - 7.3e-12 45.2 0.0 2e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 KPI43018.1 - 9e-11 41.1 4.7 1.6e-10 40.3 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 KPI43018.1 - 4.9e-06 26.4 3.7 1.1e-05 25.4 0.0 3.3 4 0 0 4 4 4 1 Myb-like DNA-binding domain BRF1 PF07741.8 KPI43018.1 - 4.9 7.4 15.9 55 4.0 0.0 4.1 3 1 0 3 3 3 0 Brf1-like TBP-binding domain PP2C PF00481.16 KPI43019.1 - 2.8e-26 92.4 0.0 8.8e-26 90.8 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Spindle_Spc25 PF08234.7 KPI43020.1 - 3.7e-10 39.6 0.6 3.5e-09 36.5 0.0 2.7 2 1 1 3 3 3 1 Chromosome segregation protein Spc25 IncA PF04156.9 KPI43020.1 - 0.0011 18.5 15.7 0.0016 18.0 10.9 1.2 1 0 0 1 1 1 1 IncA protein GBP_C PF02841.9 KPI43020.1 - 0.028 13.5 13.6 0.042 13.0 9.4 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Cir_Bir_Yir PF06022.6 KPI43020.1 - 0.035 13.3 3.8 0.048 12.8 2.7 1.1 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Filament PF00038.16 KPI43020.1 - 0.056 12.9 15.9 0.076 12.4 11.0 1.1 1 0 0 1 1 1 0 Intermediate filament protein Striatin PF08232.7 KPI43020.1 - 0.098 12.9 16.4 0.26 11.5 11.1 1.8 1 1 1 2 2 2 0 Striatin family PspA_IM30 PF04012.7 KPI43020.1 - 0.14 11.5 20.2 0.33 10.2 14.0 1.5 1 1 0 1 1 1 0 PspA/IM30 family IFT57 PF10498.4 KPI43020.1 - 0.19 10.4 13.0 0.24 10.0 9.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Rgp1 PF08737.5 KPI43020.1 - 0.2 10.6 10.2 0.26 10.3 7.1 1.1 1 0 0 1 1 1 0 Rgp1 Macoilin PF09726.4 KPI43020.1 - 0.39 8.9 12.7 0.49 8.6 8.8 1.1 1 0 0 1 1 1 0 Transmembrane protein FUSC PF04632.7 KPI43020.1 - 0.48 8.7 6.6 0.62 8.4 4.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.3 KPI43020.1 - 0.53 10.1 23.5 0.83 9.5 16.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 KPI43020.1 - 0.88 9.6 13.6 1.4 9.0 9.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family OmpH PF03938.9 KPI43020.1 - 0.9 9.4 23.3 2.2 8.1 16.2 1.6 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.17 KPI43020.1 - 0.96 9.4 15.0 1.9 8.5 0.1 2.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.6 KPI43020.1 - 1.3 8.9 12.7 2.4 8.0 2.7 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_23 PF13476.1 KPI43020.1 - 1.3 9.2 12.7 2.1 8.6 8.8 1.3 1 0 0 1 1 1 0 AAA domain DUF972 PF06156.8 KPI43020.1 - 1.4 9.3 14.7 0.26 11.6 3.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Tox-URI2 PF15653.1 KPI43020.1 - 2.1 8.6 5.1 3 8.0 2.7 1.9 2 1 0 2 2 1 0 URI fold toxin 2 Spc24 PF08286.6 KPI43020.1 - 2.2 7.9 19.6 1.6 8.4 6.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TBPIP PF07106.8 KPI43020.1 - 2.6 7.5 14.8 4.3 6.8 10.3 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ax_dynein_light PF10211.4 KPI43020.1 - 3.1 7.6 18.2 2 8.1 2.5 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain FemAB PF02388.11 KPI43020.1 - 3.3 6.2 9.6 70 1.9 8.1 2.1 2 1 0 2 2 2 0 FemAB family APG6 PF04111.7 KPI43020.1 - 4 6.3 19.4 0.092 11.7 1.2 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 SlyX PF04102.7 KPI43020.1 - 4.5 7.7 18.7 12 6.3 2.3 2.5 1 1 1 2 2 2 0 SlyX DUF4407 PF14362.1 KPI43020.1 - 4.8 6.0 12.4 9 5.1 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ApoO PF09769.4 KPI43020.1 - 5 6.8 9.2 4.5 6.9 0.1 2.1 1 1 1 2 2 2 0 Apolipoprotein O GLE1 PF07817.8 KPI43020.1 - 5.7 5.7 10.6 8.1 5.2 7.3 1.2 1 0 0 1 1 1 0 GLE1-like protein FliD_C PF07195.7 KPI43020.1 - 6.4 5.9 17.0 17 4.6 11.2 1.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus FlaC_arch PF05377.6 KPI43020.1 - 6.8 6.6 7.1 4.3 7.3 1.1 2.7 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.14 KPI43020.1 - 9.3 3.9 9.2 15 3.3 6.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pex24p PF06398.6 KPI43021.1 - 6.7e-55 186.3 14.3 3.9e-54 183.7 9.9 1.9 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin DnaJ PF00226.26 KPI43022.1 - 4.6e-18 64.6 0.4 4.6e-18 64.6 0.3 1.7 2 0 0 2 2 2 1 DnaJ domain Noc2 PF03715.8 KPI43023.1 - 7.7e-18 64.3 0.1 9.5e-18 64.0 0.1 1.1 1 0 0 1 1 1 1 Noc2p family Epimerase PF01370.16 KPI43024.1 - 3.2e-20 72.5 0.0 5e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI43024.1 - 5e-13 48.3 0.0 1.3e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KPI43024.1 - 9.1e-10 38.8 0.1 2.4e-09 37.4 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 KPI43024.1 - 6.7e-09 35.0 0.1 2.8e-07 29.7 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KPI43024.1 - 3.3e-08 33.6 0.1 5.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI43024.1 - 2.6e-07 30.4 0.0 4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KPI43024.1 - 0.00036 19.8 0.1 0.0025 17.1 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 KPI43024.1 - 0.0011 17.9 0.2 0.0021 16.9 0.1 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain UPF1_Zn_bind PF09416.5 KPI43024.1 - 0.2 11.2 0.0 2.6 7.6 0.0 2.1 2 0 0 2 2 2 0 RNA helicase (UPF2 interacting domain) Glyco_hydro_2 PF00703.16 KPI43025.1 - 4.6e-10 39.9 0.0 1.3e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KPI43025.1 - 4.3e-09 36.1 0.1 1.9e-08 34.0 0.0 2.2 3 0 0 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain RRM_1 PF00076.17 KPI43026.1 - 7.9e-47 156.7 0.1 7.4e-18 63.9 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI43026.1 - 9.8e-38 127.9 0.0 3e-14 52.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI43026.1 - 2.7e-24 84.7 0.2 9.1e-10 38.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KPI43026.1 - 8.1e-05 22.3 0.1 2 8.2 0.0 3.6 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif TPR_14 PF13428.1 KPI43026.1 - 0.00016 22.0 1.0 0.061 13.9 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Lsm_interact PF05391.6 KPI43026.1 - 0.001 18.3 0.1 0.0038 16.5 0.1 2.0 1 0 0 1 1 1 1 Lsm interaction motif DUF1866 PF08952.6 KPI43026.1 - 0.083 12.4 0.0 14 5.1 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1866) Cupin_2 PF07883.6 KPI43027.1 - 1.3e-06 27.7 0.1 2.9e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Cupin domain Tubulin_C PF03953.12 KPI43028.1 - 0.069 13.1 0.0 0.27 11.3 0.0 2.0 1 0 0 1 1 1 0 Tubulin C-terminal domain zf-U1 PF06220.7 KPI43029.1 - 9.2e-22 76.3 2.6 1.3e-21 75.8 1.8 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 KPI43029.1 - 0.027 14.5 4.0 0.066 13.3 2.8 1.6 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 KPI43029.1 - 0.16 11.7 0.1 0.22 11.3 0.1 1.0 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) F_bP_aldolase PF01116.15 KPI43031.1 - 5.1e-100 334.2 0.1 5.7e-100 334.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DAG_kinase_N PF14513.1 KPI43031.1 - 0.065 13.4 0.2 0.2 11.8 0.1 1.8 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DUF2973 PF11189.3 KPI43031.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) FA_desaturase PF00487.19 KPI43032.1 - 0.11 11.8 0.2 0.12 11.7 0.2 1.0 1 0 0 1 1 1 0 Fatty acid desaturase UPF0197 PF05251.7 KPI43032.1 - 0.31 11.3 5.0 1.2 9.4 3.5 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0197) ADH_N PF08240.7 KPI43033.1 - 1.5e-20 73.0 0.2 3e-20 71.9 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI43033.1 - 3.4e-12 46.0 0.0 8e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 KPI43034.1 - 1.8e-16 59.8 0.5 2.4e-16 59.3 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Band_7 PF01145.20 KPI43035.1 - 2.9e-26 92.4 1.7 5.6e-26 91.5 1.2 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Fungal_trans PF04082.13 KPI43036.1 - 1.5e-24 86.3 0.2 4e-24 84.8 0.1 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain CENP-B_dimeris PF09026.5 KPI43037.1 - 0.55 10.4 7.7 1.8 8.8 5.3 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HIT PF01230.18 KPI43038.1 - 4.1e-21 75.3 0.5 6.6e-21 74.6 0.3 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KPI43038.1 - 6.8e-15 55.3 0.0 1.2e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KPI43038.1 - 2.5e-07 30.3 0.0 3.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CSTF2_hinge PF14327.1 KPI43038.1 - 0.2 11.7 0.8 0.24 11.5 0.0 1.5 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KPI43039.1 - 1.4e-49 165.6 0.0 3.1e-17 61.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI43039.1 - 1.2e-39 134.0 0.0 2.2e-14 53.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI43039.1 - 2e-20 72.3 0.0 3.8e-06 26.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KPI43039.1 - 0.0012 18.5 0.1 6.6 6.5 0.0 3.8 3 2 0 3 3 3 1 Limkain b1 RRM_3 PF08777.6 KPI43039.1 - 0.0013 18.5 0.0 6.3 6.7 0.0 3.5 3 0 0 3 3 3 1 RNA binding motif GRP PF07172.6 KPI43039.1 - 0.012 16.0 15.3 0.012 16.0 10.6 4.6 4 1 1 5 5 5 0 Glycine rich protein family SPOR PF05036.8 KPI43039.1 - 0.015 15.4 0.3 6.4 7.0 0.0 3.4 3 0 0 3 3 3 0 Sporulation related domain ATP-grasp_2 PF08442.5 KPI43039.1 - 0.018 14.4 0.0 3.3 7.0 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain MFS_1 PF07690.11 KPI43040.1 - 1.4e-42 145.6 32.2 1.4e-42 145.6 22.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KPI43040.1 - 2e-10 39.5 2.2 3.2e-10 38.8 1.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KPI43040.1 - 2.5e-10 39.5 11.6 2.5e-10 39.5 8.0 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter DUF2178 PF09946.4 KPI43040.1 - 0.0071 16.0 1.4 0.0071 16.0 0.9 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2178) Herpes_US9 PF06072.6 KPI43040.1 - 1.5 8.6 8.0 3.5 7.5 0.6 3.3 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 Ran_BP1 PF00638.13 KPI43041.1 - 4.7e-09 36.3 0.0 8.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 KPI43041.1 - 0.0005 20.3 0.3 0.0005 20.3 0.2 7.1 6 0 0 6 6 6 1 NUP50 (Nucleoporin 50 kDa) Nucleoporin_FG PF13634.1 KPI43041.1 - 0.0069 16.6 38.2 0.0069 16.6 26.5 12.6 3 3 7 10 10 10 3 Nucleoporin FG repeat region MFS_1 PF07690.11 KPI43042.1 - 9.3e-30 103.5 30.5 6.2e-28 97.5 7.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI43042.1 - 1.8e-14 53.1 0.9 1.8e-14 53.1 0.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 KPI43042.1 - 0.045 13.5 6.1 9.5 6.0 0.0 3.9 4 0 0 4 4 4 0 MFS_1 like family BT1 PF03092.11 KPI43042.1 - 0.14 10.8 9.2 0.012 14.3 1.0 2.2 2 0 0 2 2 2 0 BT1 family FMN_dh PF01070.13 KPI43043.1 - 2.2e-74 250.4 0.0 5.4e-53 180.0 0.0 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KPI43043.1 - 1.1e-14 53.9 0.0 2.6e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KPI43043.1 - 8.5e-05 21.6 0.1 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KPI43043.1 - 0.00011 21.2 0.1 0.0002 20.3 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KPI43043.1 - 0.067 12.3 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Ribul_P_3_epim PF00834.14 KPI43043.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DHO_dh PF01180.16 KPI43043.1 - 0.19 10.6 0.0 0.34 9.8 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase adh_short PF00106.20 KPI43044.1 - 6.4e-13 48.9 0.1 1.2e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI43044.1 - 2.1e-06 27.5 0.4 7.1e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 KR domain Muted PF14942.1 KPI43045.1 - 0.072 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein YrhK PF14145.1 KPI43045.1 - 0.26 11.0 18.1 1.2 8.9 0.0 4.3 3 2 1 4 4 4 0 YrhK-like protein Pribosyltran PF00156.22 KPI43046.1 - 3e-16 59.2 0.0 4.1e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KPI43046.1 - 0.019 14.1 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Fungal_trans PF04082.13 KPI43047.1 - 6.8e-12 44.8 0.0 1.3e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TFIIB PF00382.14 KPI43048.1 - 8.8e-23 79.9 0.0 5e-17 61.4 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat adh_short PF00106.20 KPI43048.1 - 3.8e-18 65.9 0.4 1.1e-17 64.4 0.2 1.9 2 0 0 2 2 2 1 short chain dehydrogenase BRF1 PF07741.8 KPI43048.1 - 1.4e-15 57.2 0.0 1.4e-15 57.2 0.0 3.6 3 1 0 3 3 3 1 Brf1-like TBP-binding domain adh_short_C2 PF13561.1 KPI43048.1 - 6.3e-12 45.7 0.0 1.1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI43048.1 - 4.3e-07 29.7 0.3 3.3e-06 26.8 0.1 2.5 2 1 0 2 2 2 1 KR domain DUF4023 PF13215.1 KPI43048.1 - 0.023 14.4 0.6 0.023 14.4 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) THF_DHG_CYH_C PF02882.14 KPI43048.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pkinase PF00069.20 KPI43049.1 - 5.1e-70 235.5 0.0 6.8e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI43049.1 - 1.2e-32 112.9 0.0 1.9e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KPI43049.1 - 3e-09 37.2 0.2 8.3e-09 35.8 0.1 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KPI43049.1 - 0.00034 19.6 0.0 0.00057 18.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Glyco_transf_20 PF00982.16 KPI43050.1 - 8.2e-194 644.4 0.0 9.5e-194 644.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 LNP1 PF15419.1 KPI43050.1 - 0.0034 17.4 0.1 0.0057 16.7 0.1 1.2 1 0 0 1 1 1 1 Leukemia NUP98 fusion partner 1 DUF4066 PF13278.1 KPI43051.1 - 8.5e-25 86.9 0.0 1.1e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KPI43051.1 - 7.9e-07 28.6 0.0 1.1e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family NifU_N PF01592.11 KPI43051.1 - 0.096 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 NifU-like N terminal domain zf-CCCH PF00642.19 KPI43052.1 - 0.0001 21.8 2.4 0.00019 21.0 1.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KPI43052.1 - 0.045 13.7 1.0 0.077 13.0 0.7 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type AT_hook PF02178.14 KPI43052.1 - 0.18 11.6 3.6 0.71 9.7 2.5 2.1 1 0 0 1 1 1 0 AT hook motif Glyco_hydro_18 PF00704.23 KPI43053.1 - 1.2e-97 327.4 8.5 1.5e-97 327.1 5.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF221 PF02714.10 KPI43054.1 - 2.7e-106 355.1 23.6 5.8e-106 354.0 13.8 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KPI43054.1 - 7.1e-42 142.6 3.1 7.1e-42 142.6 2.1 3.2 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KPI43054.1 - 2.9e-15 55.9 0.4 7.3e-15 54.6 0.3 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KPI43054.1 - 3.1e-15 56.4 1.0 8e-15 55.1 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 KPI43054.1 - 0.0016 18.3 0.1 0.0048 16.8 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KPI43054.1 - 0.019 14.6 0.6 0.2 11.3 0.4 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI43054.1 - 0.058 13.2 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NIPSNAP PF07978.8 KPI43055.1 - 3.9e-38 129.5 0.4 4.6e-27 93.9 0.0 2.4 2 0 0 2 2 2 2 NIPSNAP ubiquitin PF00240.18 KPI43056.1 - 8.1e-05 21.9 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DIOX_N PF14226.1 KPI43057.1 - 3.1e-29 101.8 0.0 4.1e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI43057.1 - 4.3e-19 68.6 0.0 7.1e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.17 KPI43058.1 - 2.2e-41 139.2 0.6 1.2e-19 69.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI43058.1 - 2.6e-32 110.6 0.1 8.9e-18 64.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KPI43058.1 - 3.4e-25 88.1 0.1 1.3e-24 86.2 0.1 2.0 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 KPI43058.1 - 6.5e-22 77.1 0.0 3.2e-09 36.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KPI43058.1 - 0.095 12.5 0.0 0.095 12.5 0.0 2.9 3 1 0 3 3 3 0 RNA binding motif ALIX_LYPXL_bnd PF13949.1 KPI43059.1 - 0.088 11.7 0.1 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF3425 PF11905.3 KPI43060.1 - 7.5e-22 77.6 0.2 1.2e-21 76.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Lipase_GDSL_2 PF13472.1 KPI43061.1 - 1.3e-21 77.5 0.0 1.6e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KPI43061.1 - 0.0005 19.9 0.1 1 9.1 0.0 2.9 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase PHP PF02811.14 KPI43062.1 - 2.4e-13 50.2 0.1 4.7e-13 49.3 0.0 1.5 2 0 0 2 2 2 1 PHP domain WSC PF01822.14 KPI43064.1 - 2.6e-15 56.0 12.3 2.6e-15 56.0 8.6 3.2 3 0 0 3 3 3 2 WSC domain Lactamase_B_2 PF12706.2 KPI43066.1 - 1.5e-30 106.2 0.0 2e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KPI43066.1 - 1.4e-10 41.1 0.0 2.8e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KPI43066.1 - 0.013 15.1 0.1 0.14 11.8 0.0 2.4 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily DUF3816 PF12822.2 KPI43069.1 - 0.012 15.5 4.9 0.025 14.4 3.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Sensor PF13796.1 KPI43069.1 - 0.7 9.4 10.1 6.7 6.2 0.0 2.3 2 1 0 2 2 2 0 Putative sensor DUF2637 PF10935.3 KPI43069.1 - 0.74 9.7 6.6 10 6.0 4.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2637) PARP PF00644.15 KPI43070.1 - 4.1e-61 206.0 0.1 6.8e-61 205.2 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KPI43070.1 - 1.3e-31 108.9 0.1 2.3e-31 108.2 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 KPI43070.1 - 3.8e-22 78.0 0.3 8.4e-22 76.9 0.2 1.6 1 0 0 1 1 1 1 WGR domain Fungal_trans PF04082.13 KPI43071.1 - 4e-28 98.0 0.0 9.4e-28 96.7 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2339 PF10101.4 KPI43071.1 - 0.17 10.1 0.8 0.24 9.6 0.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) adh_short PF00106.20 KPI43072.1 - 8.4e-20 71.3 4.5 4.6e-19 68.9 0.0 2.2 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 KPI43072.1 - 8.3e-07 28.8 0.3 2.6e-06 27.2 0.2 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI43072.1 - 0.00022 21.0 0.0 0.0003 20.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF4157 PF13699.1 KPI43072.1 - 0.021 14.9 0.1 0.052 13.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) ATP-synt_C PF00137.16 KPI43072.1 - 0.41 10.5 5.3 0.78 9.6 3.6 1.4 1 0 0 1 1 1 0 ATP synthase subunit C S_layer_C PF05124.7 KPI43073.1 - 0.024 14.2 0.1 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 S-layer like family, C-terminal region KfrA_N PF11740.3 KPI43073.1 - 0.024 15.0 0.3 0.038 14.4 0.2 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term eIF3_N PF09440.5 KPI43073.1 - 0.04 14.0 0.8 0.058 13.5 0.6 1.2 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain adh_short_C2 PF13561.1 KPI43074.1 - 6.4e-30 104.6 0.1 7.2e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI43074.1 - 2.2e-20 73.2 1.8 2.2e-20 73.2 1.3 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KPI43074.1 - 3.3e-09 36.6 0.3 6.4e-09 35.7 0.2 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KPI43074.1 - 0.017 14.0 0.0 0.044 12.6 0.0 1.8 1 1 0 1 1 1 0 Male sterility protein YjeF_N PF03853.10 KPI43074.1 - 0.017 14.7 0.1 0.038 13.5 0.0 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus DUF1776 PF08643.5 KPI43074.1 - 0.085 11.9 0.0 0.16 11.0 0.0 1.3 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) RTA1 PF04479.8 KPI43075.1 - 2.1e-27 96.0 0.0 3.5e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 RTA1 like protein Ca_chan_IQ PF08763.6 KPI43075.1 - 0.02 14.0 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain DEAD PF00270.24 KPI43076.1 - 1.6e-43 148.1 0.1 3e-43 147.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI43076.1 - 7.9e-22 76.9 0.0 2.2e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KPI43076.1 - 0.00073 18.0 0.2 0.29 9.4 0.1 3.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1253) F-box-like PF12937.2 KPI43077.1 - 0.004 16.8 0.0 0.0095 15.6 0.0 1.7 1 1 0 1 1 1 1 F-box-like CBFD_NFYB_HMF PF00808.18 KPI43078.1 - 1.1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KPI43078.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 BUD22 PF09073.5 KPI43078.1 - 0.025 13.6 12.2 0.035 13.1 8.4 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 KPI43078.1 - 0.75 7.6 29.0 1.1 7.0 20.1 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 KPI43078.1 - 1.2 8.3 24.0 1.8 7.7 16.6 1.2 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.6 KPI43078.1 - 4.9 6.9 9.6 9.5 6.0 6.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Peptidase_M14 PF00246.19 KPI43079.1 - 1.7e-73 247.6 0.0 3.5e-73 246.6 0.0 1.5 1 1 1 2 2 2 1 Zinc carboxypeptidase TMF_TATA_bd PF12325.3 KPI43080.1 - 0.021 14.5 4.1 0.062 13.0 2.8 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1219 PF06755.7 KPI43080.1 - 0.03 13.8 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1219) HalX PF08663.5 KPI43080.1 - 0.23 11.4 6.3 0.14 12.1 0.3 3.2 3 1 0 3 3 3 0 HalX domain Mt_ATP-synt_B PF05405.9 KPI43080.1 - 0.38 10.1 3.5 0.82 9.1 2.4 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF4404 PF14357.1 KPI43080.1 - 0.43 11.0 3.6 0.86 10.0 0.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) BBP1_C PF15272.1 KPI43080.1 - 0.91 9.0 12.5 0.045 13.2 4.7 1.7 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Prefoldin_2 PF01920.15 KPI43080.1 - 1.1 9.0 11.0 8.2 6.2 0.5 3.2 3 0 0 3 3 3 0 Prefoldin subunit V_ATPase_I PF01496.14 KPI43080.1 - 1.2 6.8 3.3 2.9 5.6 2.3 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KPI43080.1 - 2.1 7.9 8.7 15 5.1 6.0 2.2 1 1 0 1 1 1 0 IncA protein Mnd1 PF03962.10 KPI43080.1 - 2.1 7.9 8.0 5.3 6.6 0.3 2.5 2 0 0 2 2 2 0 Mnd1 family TPR_16 PF13432.1 KPI43082.1 - 0.05 14.2 0.1 0.05 14.2 0.1 2.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KPI43082.1 - 0.16 11.8 1.7 0.52 10.2 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KPI43082.1 - 0.19 12.4 2.9 0.43 11.3 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat GRP PF07172.6 KPI43082.1 - 0.56 10.7 8.2 1 9.9 5.7 1.4 1 0 0 1 1 1 0 Glycine rich protein family ATP-synt_DE PF00401.15 KPI43082.1 - 8.8 6.3 8.5 3.6 7.5 1.1 2.9 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain BRCT PF00533.21 KPI43083.1 - 9.8e-12 44.8 0.0 1.7e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Glycos_transf_1 PF00534.15 KPI43084.1 - 9.3e-20 70.7 0.0 1.6e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KPI43084.1 - 0.0054 16.4 0.0 0.016 14.9 0.0 1.7 1 1 1 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 KPI43084.1 - 1.8 8.6 5.4 0.24 11.5 0.7 1.9 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain CFEM PF05730.6 KPI43085.1 - 4e-12 45.7 11.3 6.9e-12 45.0 7.8 1.4 1 0 0 1 1 1 1 CFEM domain DUF4131 PF13567.1 KPI43085.1 - 7.5 5.9 16.2 0.065 12.6 2.5 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) NIF PF03031.13 KPI43086.1 - 4e-51 172.8 0.2 6.1e-51 172.2 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase adh_short PF00106.20 KPI43087.1 - 2.7e-28 98.9 4.4 4.1e-28 98.3 3.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI43087.1 - 9.7e-13 48.1 1.3 1.7e-12 47.3 0.9 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KPI43087.1 - 3.2e-08 32.8 0.5 4.4e-08 32.3 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KPI43087.1 - 4.3e-07 29.5 0.6 1.1e-06 28.3 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KPI43087.1 - 0.0029 17.3 0.6 0.0078 15.9 0.4 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_tran_WecB PF03808.8 KPI43087.1 - 0.01 15.2 0.1 0.036 13.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family p450 PF00067.17 KPI43088.1 - 4e-37 127.8 0.0 5e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TEA PF01285.13 KPI43089.1 - 6.7e-56 190.2 0.0 6.7e-56 190.2 0.0 4.3 3 2 1 4 4 4 1 TEA/ATTS domain family Nucleoporin_FG PF13634.1 KPI43090.1 - 0.0029 17.8 10.4 0.0029 17.8 7.2 3.7 3 1 0 3 3 3 1 Nucleoporin FG repeat region Ribosomal_L22 PF00237.14 KPI43091.1 - 2e-13 50.1 1.4 2.2e-06 27.5 0.2 2.7 3 0 0 3 3 3 2 Ribosomal protein L22p/L17e Phage_Mu_F PF04233.9 KPI43091.1 - 9.7 6.7 7.7 2.7 8.5 0.3 2.7 1 1 1 2 2 2 0 Phage Mu protein F like protein NmrA PF05368.8 KPI43092.1 - 1.2e-23 83.5 0.1 5e-23 81.5 0.1 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI43092.1 - 1.2e-14 54.6 0.1 2.2e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding HSP70 PF00012.15 KPI43092.1 - 8.5e-07 27.2 0.2 0.00032 18.7 0.0 2.7 3 0 0 3 3 3 2 Hsp70 protein Epimerase PF01370.16 KPI43092.1 - 3e-06 26.8 0.0 5.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI43092.1 - 0.0037 15.9 0.0 0.0092 14.7 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KPI43092.1 - 0.011 15.4 1.5 0.021 14.4 0.1 2.0 2 0 0 2 2 2 0 KR domain NAD_binding_4 PF07993.7 KPI43092.1 - 0.011 14.6 0.0 3.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein adh_short PF00106.20 KPI43092.1 - 0.023 14.6 0.4 0.023 14.6 0.3 2.1 2 0 0 2 2 2 0 short chain dehydrogenase Saccharop_dh PF03435.13 KPI43092.1 - 0.033 13.1 0.2 0.068 12.1 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KPI43092.1 - 0.044 14.0 0.2 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KPI43092.1 - 0.057 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Noc2 PF03715.8 KPI43093.1 - 4.5e-75 252.2 0.0 4.5e-75 252.2 0.0 2.0 3 0 0 3 3 3 1 Noc2p family TENA_THI-4 PF03070.11 KPI43093.1 - 0.037 13.7 0.1 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 TENA/THI-4/PQQC family Leu_Phe_trans PF03588.9 KPI43093.1 - 0.043 12.9 0.1 0.088 11.9 0.0 1.4 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase XPC-binding PF09280.6 KPI43093.1 - 0.065 12.7 0.1 8.5 5.9 0.0 2.8 3 0 0 3 3 3 0 XPC-binding domain Homeobox PF00046.24 KPI43094.1 - 1.7e-17 62.7 0.7 3.8e-16 58.4 1.0 2.3 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KPI43094.1 - 0.00022 20.8 0.1 0.00059 19.4 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Coatomer_WDAD PF04053.9 KPI43095.1 - 2.6e-149 497.8 0.0 5.5e-149 496.7 0.0 1.4 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 KPI43095.1 - 1.1e-26 91.6 6.5 1.2e-08 34.4 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 KPI43095.1 - 0.00051 18.2 0.1 0.48 8.4 0.0 3.5 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 KPI43095.1 - 0.057 12.9 0.0 0.45 10.0 0.0 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_4 PF07721.9 KPI43095.1 - 0.14 12.6 4.8 4.9 7.8 0.3 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR_1 PF12854.2 KPI43095.1 - 0.28 10.7 1.4 29 4.2 0.0 3.1 3 0 0 3 3 3 0 PPR repeat TPR_14 PF13428.1 KPI43095.1 - 0.86 10.4 5.9 6.4 7.7 0.1 4.1 2 2 2 4 4 4 0 Tetratricopeptide repeat DUF221 PF02714.10 KPI43096.1 - 1.2e-72 244.5 18.2 5.6e-70 235.7 12.6 2.4 1 1 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KPI43096.1 - 6.1e-36 123.3 0.6 6.1e-36 123.3 0.4 1.8 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KPI43096.1 - 1.8e-16 60.4 0.1 3.4e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Med9 PF07544.8 KPI43096.1 - 0.0063 16.2 0.5 3.8 7.3 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 DUF588 PF04535.7 KPI43096.1 - 0.014 14.9 4.5 0.26 10.8 0.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF588) DUF1192 PF06698.6 KPI43096.1 - 0.12 12.2 0.5 0.25 11.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Sec16 PF12932.2 KPI43096.1 - 0.19 11.7 0.1 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region TMF_TATA_bd PF12325.3 KPI43096.1 - 0.22 11.2 1.1 0.78 9.4 0.0 2.1 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CABS1 PF15367.1 KPI43096.1 - 0.26 10.1 0.0 0.42 9.4 0.0 1.2 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 MerC PF03203.9 KPI43096.1 - 9.8 6.5 7.9 1.7 9.0 0.7 2.5 2 0 0 2 2 2 0 MerC mercury resistance protein GCV_T PF01571.16 KPI43097.1 - 3.7e-56 189.8 0.0 1.5e-29 102.8 0.0 2.1 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KPI43097.1 - 4.1e-18 65.1 0.2 1e-17 63.8 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain RTA1 PF04479.8 KPI43098.1 - 2.9e-45 154.4 6.4 3.9e-45 154.0 4.4 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF805 PF05656.9 KPI43098.1 - 7 6.5 7.8 35 4.2 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF805) Abhydrolase_6 PF12697.2 KPI43100.1 - 2.9e-27 96.0 0.0 3.6e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI43100.1 - 6.2e-17 61.6 0.0 2.6e-16 59.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI43100.1 - 3.9e-13 49.5 0.0 1.6e-08 34.3 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KPI43100.1 - 2.6e-09 36.8 0.0 0.0087 15.5 0.0 3.1 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KPI43100.1 - 4.3e-05 22.8 0.0 0.059 12.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 KPI43100.1 - 8.1e-05 22.0 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KPI43100.1 - 0.0088 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 KPI43100.1 - 0.038 12.4 0.0 0.082 11.3 0.0 1.5 2 0 0 2 2 2 0 Ndr family BAAT_C PF08840.6 KPI43100.1 - 0.12 12.0 0.0 0.6 9.7 0.0 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Not1 PF04054.10 KPI43101.1 - 2e-83 280.3 0.0 5e-83 279.0 0.0 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KPI43101.1 - 6.2e-44 149.2 1.8 6.2e-44 149.2 1.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) GFO_IDH_MocA PF01408.17 KPI43102.1 - 1.4e-25 90.1 0.0 2.2e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 KPI43102.1 - 0.034 14.5 0.0 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF2013 PF09431.5 KPI43103.1 - 2.3e-53 179.7 2.6 4.6e-53 178.7 1.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) MFS_1 PF07690.11 KPI43104.1 - 9.8e-29 100.1 43.1 1.4e-28 99.6 28.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 KPI43104.1 - 0.00024 21.0 0.3 0.00024 21.0 0.2 3.6 3 1 0 3 3 3 1 Protein of unknown function (DUF1228) PDR_CDR PF06422.7 KPI43104.1 - 0.27 10.9 2.1 0.54 9.9 0.0 2.6 2 0 0 2 2 2 0 CDR ABC transporter DUF2830 PF11125.3 KPI43104.1 - 2.1 8.1 5.6 0.42 10.3 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2830) Porin_3 PF01459.17 KPI43105.1 - 9.2e-63 212.0 5.6 1.2e-62 211.6 3.9 1.2 1 0 0 1 1 1 1 Eukaryotic porin DAP10 PF07213.6 KPI43106.1 - 0.0022 17.7 0.4 0.0051 16.5 0.3 1.5 1 0 0 1 1 1 1 DAP10 membrane protein TMEM154 PF15102.1 KPI43106.1 - 0.015 14.9 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family IncA PF04156.9 KPI43106.1 - 0.044 13.3 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 IncA protein Macoilin PF09726.4 KPI43106.1 - 0.075 11.3 4.1 0.14 10.4 2.8 1.4 1 0 0 1 1 1 0 Transmembrane protein Pox_A12 PF04651.8 KPI43106.1 - 0.08 13.0 6.3 0.23 11.5 4.4 1.7 1 0 0 1 1 1 0 Poxvirus A12 protein DUF2029 PF09594.5 KPI43106.1 - 0.091 12.2 1.2 2.1 7.7 0.3 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2029) EBP PF05241.7 KPI43107.1 - 2.1e-52 176.9 15.7 2.5e-52 176.7 10.9 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF1601 PF07671.6 KPI43107.1 - 0.3 10.7 1.4 0.51 10.0 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1601) Cupin_5 PF06172.6 KPI43109.1 - 8.4e-36 122.9 0.0 6.8e-35 119.9 0.0 2.0 1 1 0 1 1 1 1 Cupin superfamily (DUF985) NAD_binding_10 PF13460.1 KPI43110.1 - 4.5e-08 33.3 0.1 6.8e-08 32.7 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding HIM1 PF08732.5 KPI43110.1 - 3.4e-07 29.0 0.0 6e-07 28.2 0.0 1.4 2 0 0 2 2 2 1 HIM1 Semialdhyde_dh PF01118.19 KPI43110.1 - 2.5e-06 27.7 0.0 5.1e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KPI43110.1 - 0.00058 19.1 0.0 0.00092 18.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DUF1471 PF07338.8 KPI43110.1 - 0.002 17.7 0.2 0.0042 16.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) Epimerase PF01370.16 KPI43110.1 - 0.0022 17.4 0.0 0.029 13.8 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KPI43110.1 - 0.067 12.0 0.0 0.72 8.7 0.0 2.2 2 1 1 3 3 3 0 Male sterility protein DUF374 PF04028.8 KPI43110.1 - 0.077 12.2 0.3 0.65 9.2 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF374) GCIP PF13324.1 KPI43111.1 - 2e-08 33.8 0.0 2.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting p450 PF00067.17 KPI43112.1 - 4.5e-46 157.3 0.0 5.9e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DNA_pol3_chi PF04364.8 KPI43112.1 - 0.046 13.5 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC DIOX_N PF14226.1 KPI43113.1 - 1.8e-17 63.8 0.0 2.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI43113.1 - 3.1e-15 56.2 0.0 4.9e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PNP_UDP_1 PF01048.15 KPI43114.1 - 2.8e-13 49.3 0.0 4.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.2 KPI43115.1 - 4.2e-43 145.5 6.7 7.6e-13 48.6 0.4 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KPI43115.1 - 2.7e-30 102.6 3.6 2.3e-06 27.1 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KPI43115.1 - 1.1e-24 86.3 0.4 2.1e-08 34.4 0.0 3.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KPI43115.1 - 6.5e-23 80.2 1.6 3.6e-07 30.2 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI43115.1 - 3.1e-20 70.2 1.9 0.00052 19.9 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat U79_P34 PF03064.11 KPI43115.1 - 0.015 14.8 0.3 0.021 14.3 0.2 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NDT80_PhoG PF05224.7 KPI43116.1 - 5.9e-36 124.2 0.9 9.2e-36 123.5 0.6 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF383 PF04063.9 KPI43117.1 - 4.4e-56 189.4 0.1 2.5e-55 187.0 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KPI43117.1 - 4.1e-21 74.3 1.3 6.7e-21 73.6 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF384) HEAT_2 PF13646.1 KPI43117.1 - 0.077 13.2 0.2 1.7 8.9 0.1 3.2 2 1 0 2 2 2 0 HEAT repeats Rhodanese PF00581.15 KPI43118.1 - 1.2e-08 35.2 0.0 2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain adh_short PF00106.20 KPI43120.1 - 1.4e-26 93.4 0.0 1.7e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI43120.1 - 8.7e-16 58.4 0.0 1.1e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI43120.1 - 6.7e-09 35.6 0.0 1.2e-08 34.8 0.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI43120.1 - 4e-05 23.1 0.0 6.9e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KPI43120.1 - 0.052 13.3 0.2 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KPI43120.1 - 0.08 12.9 0.0 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding Fasciclin PF02469.17 KPI43121.1 - 6.6e-24 84.3 0.0 2.4e-12 46.9 0.0 2.4 2 1 0 2 2 2 2 Fasciclin domain SKG6 PF08693.5 KPI43121.1 - 0.012 14.9 1.2 0.024 13.9 0.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VSP PF03302.8 KPI43121.1 - 0.021 13.5 0.0 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF3485 PF11984.3 KPI43121.1 - 0.03 13.4 0.0 0.073 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) DUF4064 PF13273.1 KPI43121.1 - 0.061 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF1996 PF09362.5 KPI43122.1 - 7.2e-87 290.9 3.6 1e-86 290.4 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 KPI43122.1 - 5.2e-37 125.6 27.0 5.3e-20 71.1 6.4 3.3 2 0 0 2 2 2 2 WSC domain DUF605 PF04652.11 KPI43122.1 - 0.3 10.4 33.2 0.43 9.9 23.0 1.1 1 0 0 1 1 1 0 Vta1 like Glyco_hydro_47 PF01532.15 KPI43123.1 - 4.2e-173 576.1 0.9 5e-173 575.9 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ERCC4 PF02732.10 KPI43124.1 - 5.7e-31 107.1 0.5 9.9e-31 106.4 0.3 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 KPI43124.1 - 0.0015 18.6 0.0 0.0043 17.1 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF4269 PF14091.1 KPI43124.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) adh_short PF00106.20 KPI43125.1 - 1.7e-18 67.1 0.8 2.5e-18 66.5 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI43125.1 - 3.3e-09 36.6 0.4 4.8e-09 36.1 0.3 1.3 1 0 0 1 1 1 1 KR domain FKBP_C PF00254.23 KPI43126.1 - 2.7e-27 94.6 0.1 3.2e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Nitroreductase PF00881.19 KPI43127.1 - 1.7e-13 50.7 0.0 2e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DUF1212 PF06738.7 KPI43128.1 - 2.9e-40 137.7 11.3 9.3e-37 126.3 0.3 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KPI43128.1 - 4.2e-29 101.1 30.7 7.3e-29 100.3 9.3 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF3815) GDE_N PF12439.3 KPI43128.1 - 0.15 11.2 0.7 0.24 10.6 0.0 1.5 2 0 0 2 2 2 0 Glycogen debranching enzyme N terminal Methyltransf_11 PF08241.7 KPI43129.1 - 3.8e-08 33.6 0.0 7.5e-08 32.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI43129.1 - 0.01 15.3 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KPI43129.1 - 0.021 15.1 0.0 0.052 13.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KPI43129.1 - 0.028 14.9 0.0 0.041 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KPI43129.1 - 0.049 14.1 0.0 0.066 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF897 PF05982.7 KPI43130.1 - 0.02 13.7 0.1 0.025 13.3 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF897) Acetyltransf_1 PF00583.19 KPI43131.1 - 0.001 19.0 1.0 0.0014 18.6 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI43131.1 - 0.0015 18.6 0.0 0.0053 16.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI43131.1 - 0.048 13.7 0.1 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3296 PF11726.3 KPI43131.1 - 0.12 11.9 0.3 0.19 11.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) AhpC-TSA PF00578.16 KPI43132.1 - 4.1e-11 42.6 0.0 6.1e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.1 KPI43132.1 - 7.9e-10 38.6 0.0 1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 KPI43132.1 - 1e-07 31.5 0.0 3.7e-05 23.3 0.0 2.1 1 1 1 2 2 2 2 Redoxin DUF2434 PF10361.4 KPI43132.1 - 0.007 15.4 0.0 0.0095 15.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) MFS_1 PF07690.11 KPI43133.1 - 4.9e-35 120.8 27.9 6.9e-35 120.3 19.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3169 PF11368.3 KPI43133.1 - 0.0095 15.1 0.3 0.58 9.3 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3169) ABM PF03992.11 KPI43134.1 - 0.1 12.6 0.8 0.24 11.4 0.1 1.9 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase PigN PF04987.9 KPI43135.1 - 1.3e-157 524.9 30.3 1.7e-157 524.6 21.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KPI43135.1 - 9.5e-09 35.0 1.1 1.5e-07 31.1 0.7 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KPI43135.1 - 1.2e-06 27.9 0.1 2.1e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KPI43135.1 - 1.3e-05 24.7 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Solute_trans_a PF03619.11 KPI43136.1 - 4.5e-103 344.3 9.3 5.5e-103 344.0 6.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha NAD_binding_6 PF08030.7 KPI43137.1 - 1.9e-18 66.8 0.0 3.3e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KPI43137.1 - 1.3e-16 60.4 0.0 4.7e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 KPI43137.1 - 6.7e-12 45.5 2.7 6.7e-12 45.5 1.9 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KPI43137.1 - 0.0089 16.1 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain ADP_ribosyl_GH PF03747.9 KPI43138.1 - 2.5e-58 198.1 0.9 2.9e-58 197.9 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Prenyltrans PF00432.16 KPI43139.1 - 2e-18 65.6 14.9 7.2e-06 25.4 0.0 5.4 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KPI43139.1 - 8.9e-18 64.7 0.1 3.8e-16 59.4 0.0 2.4 2 0 0 2 2 2 1 Prenyltransferase-like DNA_methylase PF00145.12 KPI43140.1 - 8.2e-34 117.2 0.0 1.5e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.3 KPI43140.1 - 0.0057 16.3 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.13 KPI43140.1 - 0.054 13.2 0.0 0.2 11.3 0.0 1.8 1 1 0 1 1 1 0 BAH domain Dynamitin PF04912.9 KPI43142.1 - 0.097 11.4 0.0 0.16 10.7 0.0 1.3 1 1 0 1 1 1 0 Dynamitin SLAC1 PF03595.12 KPI43144.1 - 5.3e-66 222.5 34.4 7.2e-66 222.0 23.9 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel MoeA_N PF03453.12 KPI43144.1 - 6.4e-27 93.8 0.1 1.2e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.19 KPI43144.1 - 3.9e-25 87.9 0.0 7.2e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain DUF373 PF04123.8 KPI43144.1 - 0.41 9.6 6.2 0.82 8.6 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF3353 PF11833.3 KPI43144.1 - 0.65 9.4 3.8 0.35 10.2 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) GPI-anchored PF10342.4 KPI43146.1 - 0.0028 18.0 0.1 0.0028 18.0 0.1 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4150 PF13665.1 KPI43146.1 - 1.7 8.5 12.4 1.6 8.6 4.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4150) HMA PF00403.21 KPI43149.1 - 1e-13 51.1 0.3 2e-13 50.2 0.2 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 KPI43149.1 - 1.1e-13 51.4 0.0 1.7e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CIA30 PF08547.7 KPI43150.1 - 4.3e-21 75.4 0.0 4.3e-10 39.6 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Transp_cyt_pur PF02133.10 KPI43152.1 - 2.8e-66 223.8 26.0 3.8e-66 223.4 18.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2458 PF10454.4 KPI43153.1 - 6.7e-31 107.2 0.1 1.7e-30 105.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2458) AAA_11 PF13086.1 KPI43155.1 - 1.5e-55 188.3 0.0 6.8e-55 186.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KPI43155.1 - 1.1e-49 168.4 0.0 1.7e-46 158.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KPI43155.1 - 4.3e-13 49.2 0.1 4.3e-08 32.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 KPI43155.1 - 5.1e-13 48.5 0.1 2.3e-12 46.4 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 KPI43155.1 - 5.5e-06 25.7 0.0 0.017 14.3 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.10 KPI43155.1 - 6.5e-05 22.8 0.0 0.00025 20.9 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KPI43155.1 - 7.5e-05 21.8 0.0 0.05 12.5 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 KPI43155.1 - 0.00037 19.9 0.0 0.0014 18.0 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 KPI43155.1 - 0.00038 19.9 0.0 0.0029 17.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Zot PF05707.7 KPI43155.1 - 0.002 17.5 0.0 0.0048 16.3 0.0 1.6 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 KPI43155.1 - 0.0023 18.0 0.0 0.0099 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.9 KPI43155.1 - 0.0025 17.4 0.0 0.083 12.5 0.0 2.5 2 0 0 2 2 2 1 Helicase AAA_16 PF13191.1 KPI43155.1 - 0.0037 17.2 0.1 0.019 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.13 KPI43155.1 - 0.0052 16.3 0.1 2.6 7.5 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KPI43155.1 - 0.0077 15.6 0.0 0.038 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KPI43155.1 - 0.017 14.6 0.0 0.042 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.24 KPI43155.1 - 0.02 15.0 0.0 0.062 13.4 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.9 KPI43155.1 - 0.027 13.4 0.0 0.76 8.6 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_5 PF07728.9 KPI43155.1 - 0.033 13.9 0.0 0.079 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 KPI43155.1 - 0.045 12.6 0.0 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD_C PF13361.1 KPI43155.1 - 0.065 12.6 0.0 0.53 9.6 0.0 2.1 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain TrwB_AAD_bind PF10412.4 KPI43155.1 - 0.069 11.7 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.12 KPI43155.1 - 0.085 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 KPI43155.1 - 0.1 12.8 0.2 3.1 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain FAD_binding_4 PF01565.18 KPI43156.1 - 2.8e-22 78.6 5.3 4.5e-22 78.0 3.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KPI43156.1 - 8.9e-06 25.5 0.1 2.2e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like PfkB PF00294.19 KPI43158.1 - 9.8e-20 70.8 0.0 1.3e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Acyltransferase PF01553.16 KPI43159.1 - 4.1e-26 90.9 0.0 8e-26 90.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Abhydrolase_3 PF07859.8 KPI43160.1 - 1.5e-22 80.2 0.1 2e-22 79.8 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KPI43160.1 - 1.3e-10 40.4 0.0 1.9e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KPI43160.1 - 0.00032 20.4 0.0 0.00071 19.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KPI43160.1 - 0.18 10.4 0.1 4 6.0 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Translin PF01997.11 KPI43161.1 - 6.8e-51 172.7 0.0 7.8e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 Translin family Septin PF00735.13 KPI43162.1 - 1.6e-09 37.2 0.0 1e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 Septin Miro PF08477.8 KPI43162.1 - 0.0019 18.6 0.0 0.0055 17.1 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 KPI43162.1 - 0.0068 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KPI43162.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 KPI43162.1 - 0.018 14.7 0.1 0.038 13.6 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 KPI43162.1 - 0.026 14.7 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KPI43162.1 - 0.026 13.9 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.1 KPI43162.1 - 0.032 15.0 0.2 0.07 13.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 KPI43162.1 - 0.038 13.6 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 KPI43162.1 - 0.09 12.3 0.1 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KPI43162.1 - 0.12 11.5 1.0 0.17 10.9 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Gtr1_RagA PF04670.7 KPI43162.1 - 0.13 11.3 0.0 3.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region NTPase_1 PF03266.10 KPI43162.1 - 0.16 11.6 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 NTPase Far-17a_AIG1 PF04750.9 KPI43165.1 - 3.8e-05 22.9 8.1 4.5e-05 22.7 5.2 1.4 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein Yip1 PF04893.12 KPI43165.1 - 0.0054 16.2 3.5 0.0054 16.2 2.4 2.9 1 1 0 2 2 2 1 Yip1 domain UL2 PF08196.6 KPI43165.1 - 0.32 10.7 7.6 5.4 6.8 0.1 2.6 2 0 0 2 2 2 0 UL2 protein DUF3816 PF12822.2 KPI43165.1 - 8.4 6.2 13.4 1.4 8.7 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) FGGY_N PF00370.16 KPI43167.1 - 3.9e-67 226.1 0.0 5.1e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 KPI43167.1 - 1.9e-56 190.7 2.8 1.3e-54 184.8 2.0 2.4 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MFS_1 PF07690.11 KPI43169.1 - 5.8e-32 110.7 35.5 1.2e-31 109.7 24.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Shugoshin_C PF07557.6 KPI43170.1 - 8.3e-11 41.1 3.6 8.3e-11 41.1 2.5 3.9 4 0 0 4 4 4 1 Shugoshin C terminus Shugoshin_N PF07558.6 KPI43170.1 - 0.0014 18.3 3.8 0.0052 16.4 2.5 2.1 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region TauD PF02668.11 KPI43171.1 - 6.3e-46 157.1 0.0 7.5e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ribosomal_L10 PF00466.15 KPI43173.1 - 2.7e-24 85.0 0.1 5.5e-24 83.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KPI43173.1 - 9.9e-21 73.9 7.8 9.9e-21 73.9 5.4 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF2414 PF10309.4 KPI43173.1 - 0.039 13.6 0.0 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2414) Chitin_synth_2 PF03142.10 KPI43174.1 - 2.7e-25 88.7 1.0 5.4e-23 81.1 1.2 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 KPI43174.1 - 9.3e-17 61.5 0.0 2.6e-16 60.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KPI43174.1 - 1.9e-16 60.3 8.0 1.9e-16 60.3 5.5 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KPI43174.1 - 0.026 14.2 0.0 8.7 5.9 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 MARVEL PF01284.18 KPI43175.1 - 2.9e-07 30.4 20.0 1.4e-06 28.1 13.9 2.1 1 1 0 1 1 1 1 Membrane-associating domain O-antigen_lig PF13425.1 KPI43175.1 - 0.0022 17.9 0.2 0.0022 17.9 0.2 2.3 1 1 1 2 2 2 1 O-antigen ligase like membrane protein HET PF06985.6 KPI43176.1 - 2e-13 50.7 0.0 2.1e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_transf_17 PF04724.8 KPI43177.1 - 3.8e-44 151.1 0.0 5e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 HET PF06985.6 KPI43178.1 - 9.6e-24 84.1 4.8 2e-21 76.6 0.1 3.0 3 0 0 3 3 3 2 Heterokaryon incompatibility protein (HET) TIP49 PF06068.8 KPI43179.1 - 1.7e-184 613.1 0.1 2e-184 612.9 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KPI43179.1 - 1.7e-10 41.2 0.1 8e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KPI43179.1 - 2.7e-10 39.6 0.1 2.4e-06 26.7 0.0 2.5 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KPI43179.1 - 3.5e-07 30.3 0.0 0.0013 18.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KPI43179.1 - 1.4e-05 25.2 0.1 0.075 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KPI43179.1 - 0.00011 21.8 0.0 0.00031 20.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KPI43179.1 - 0.00037 20.4 0.1 0.00086 19.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KPI43179.1 - 0.00094 18.3 0.1 0.002 17.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 KPI43179.1 - 0.0013 18.2 0.1 0.83 9.1 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.9 KPI43179.1 - 0.0016 18.2 0.1 0.34 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KPI43179.1 - 0.0066 15.8 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KPI43179.1 - 0.011 14.9 0.1 0.36 9.9 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 KPI43179.1 - 0.017 14.0 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 KPI43179.1 - 0.021 13.9 0.2 0.054 12.6 0.0 1.8 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.12 KPI43179.1 - 0.022 14.1 0.1 0.048 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 KPI43179.1 - 0.026 14.8 0.1 0.097 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KPI43179.1 - 0.028 15.2 0.0 0.075 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KPI43179.1 - 0.031 13.9 0.1 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 NTPase PIF1 PF05970.9 KPI43179.1 - 0.04 12.8 0.0 3.7 6.3 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase DnaB_C PF03796.10 KPI43179.1 - 0.075 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain IFT57 PF10498.4 KPI43182.1 - 0.15 10.7 10.9 0.22 10.2 7.5 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Phage_GP20 PF06810.6 KPI43182.1 - 0.23 10.9 7.9 0.26 10.7 5.0 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF3373 PF11853.3 KPI43182.1 - 1 7.7 3.6 1.5 7.2 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Exonuc_VII_L PF02601.10 KPI43182.1 - 2.3 7.3 8.2 4.1 6.5 5.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.9 KPI43182.1 - 2.5 7.6 13.8 3.8 7.0 9.6 1.2 1 0 0 1 1 1 0 IncA protein SPX PF03105.14 KPI43182.1 - 3.6 7.2 16.3 4.8 6.8 11.3 1.5 1 1 0 1 1 1 0 SPX domain DUF4404 PF14357.1 KPI43182.1 - 3.8 7.9 9.9 0.85 10.0 3.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) adh_short PF00106.20 KPI43183.1 - 7.1e-30 104.1 0.5 3.1e-29 102.0 0.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI43183.1 - 5.4e-24 85.2 0.0 7.1e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI43183.1 - 1.6e-10 40.9 0.1 3.4e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI43183.1 - 0.0013 18.1 0.1 0.028 13.8 0.1 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KPI43183.1 - 0.014 15.2 1.7 0.025 14.3 0.5 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KPI43183.1 - 0.033 14.2 0.3 0.68 9.9 0.1 2.3 1 1 1 2 2 2 0 NADH(P)-binding Abhydrolase_1 PF00561.15 KPI43184.1 - 5.2e-27 94.8 0.0 4.1e-26 91.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 KPI43184.1 - 2.2e-21 75.6 0.0 4.4e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 KPI43184.1 - 2.9e-11 43.6 0.0 7.6e-10 39.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI43184.1 - 7.4e-05 22.5 0.0 0.25 11.0 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI43184.1 - 0.052 12.7 0.0 0.5 9.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF4345 PF14248.1 KPI43185.1 - 0.0062 15.9 1.3 0.011 15.1 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4345) MMR_HSR1_C PF08438.5 KPI43186.1 - 9.2e-32 109.5 0.0 1.6e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 KPI43186.1 - 7.3e-18 64.6 0.0 1.5e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KPI43186.1 - 4.5e-07 29.2 0.0 7.5e-06 25.2 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KPI43186.1 - 0.0036 17.1 0.5 0.054 13.3 0.1 2.6 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 KPI43186.1 - 0.0071 15.7 0.1 1.1 8.6 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KPI43186.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 KPI43186.1 - 0.019 14.8 0.3 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KPI43186.1 - 0.023 14.6 0.1 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain KTI12 PF08433.5 KPI43186.1 - 0.04 13.1 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 KPI43186.1 - 0.043 14.1 0.6 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KPI43186.1 - 0.082 13.2 0.0 0.34 11.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.1 KPI43186.1 - 0.084 12.8 0.2 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain DAO PF01266.19 KPI43187.1 - 1.4e-46 159.0 0.0 1.7e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI43187.1 - 2.1e-07 30.8 0.0 5.6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI43187.1 - 0.00041 19.3 0.0 0.001 17.9 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KPI43187.1 - 0.00042 20.2 0.0 0.0037 17.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI43187.1 - 0.00086 19.4 0.0 0.0021 18.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI43187.1 - 0.0023 17.7 0.1 0.006 16.3 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KPI43187.1 - 0.012 14.7 0.0 0.04 12.9 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 KPI43187.1 - 0.032 13.0 0.0 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.13 KPI43187.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.12 KPI43187.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 KPI43187.1 - 0.18 11.1 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ING PF12998.2 KPI43188.1 - 2.3e-11 43.8 2.8 1.8e-10 41.0 1.0 2.7 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding WWbp PF10349.4 KPI43190.1 - 2e-16 60.8 2.1 3.9e-16 59.9 1.4 1.4 1 0 0 1 1 1 1 WW-domain ligand protein DUF2433 PF10360.4 KPI43190.1 - 0.056 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) Vps36_ESCRT-II PF11605.3 KPI43190.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 RhoGAP PF00620.22 KPI43191.1 - 8.7e-37 126.0 0.0 1.4e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Cytochrom_B561 PF03188.11 KPI43193.1 - 2.6e-05 24.0 7.1 2.6e-05 24.0 4.9 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2708 PF10917.3 KPI43193.1 - 0.0099 15.6 0.5 0.024 14.4 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2708) DUF4079 PF13301.1 KPI43193.1 - 0.087 12.8 13.8 0.28 11.1 4.2 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF4079) Cation_ATPase_C PF00689.16 KPI43193.1 - 0.25 10.8 4.7 0.45 10.0 3.2 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF2427 PF10348.4 KPI43193.1 - 0.29 10.7 2.0 0.64 9.6 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) PepSY_TM_1 PF13172.1 KPI43193.1 - 3.4 7.5 11.4 0.25 11.1 1.1 3.2 3 0 0 3 3 3 0 PepSY-associated TM helix AP_endonuc_2 PF01261.19 KPI43194.1 - 1.5e-24 86.5 0.1 2.2e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Ribosomal_L28 PF00830.14 KPI43195.1 - 3.3e-12 46.0 1.1 5.4e-12 45.3 0.7 1.3 1 0 0 1 1 1 1 Ribosomal L28 family TPR_MLP1_2 PF07926.7 KPI43196.1 - 0.00055 19.6 5.3 0.00055 19.6 3.7 2.7 2 1 0 3 3 2 1 TPR/MLP1/MLP2-like protein Filament PF00038.16 KPI43196.1 - 0.0075 15.7 20.3 0.069 12.6 7.1 3.1 2 1 1 3 3 3 2 Intermediate filament protein DUF3584 PF12128.3 KPI43196.1 - 0.009 13.4 19.3 0.015 12.6 13.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Flagellin_N PF00669.15 KPI43196.1 - 0.018 14.8 8.9 0.018 14.8 6.2 2.8 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region Tropomyosin_1 PF12718.2 KPI43196.1 - 0.02 14.7 29.2 0.025 14.4 12.5 2.8 2 1 1 3 3 3 0 Tropomyosin like BicD PF09730.4 KPI43196.1 - 0.027 12.8 19.0 0.026 12.9 12.6 1.5 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Fez1 PF06818.10 KPI43196.1 - 0.031 14.2 22.3 0.66 9.9 14.1 3.0 2 1 0 2 2 2 0 Fez1 DUF2443 PF10398.4 KPI43196.1 - 0.11 12.2 0.4 0.36 10.6 0.1 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF2443) AAA_13 PF13166.1 KPI43196.1 - 0.23 9.8 12.5 0.4 9.0 8.6 1.3 1 0 0 1 1 1 0 AAA domain EzrA PF06160.7 KPI43196.1 - 0.24 9.5 15.0 0.3 9.2 2.9 2.4 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Spc7 PF08317.6 KPI43196.1 - 0.35 9.5 15.9 0.75 8.4 8.8 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.7 KPI43196.1 - 0.37 11.0 6.6 18 5.7 0.6 3.7 1 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 KPI43196.1 - 0.41 10.7 15.2 0.33 11.0 2.4 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.6 KPI43196.1 - 0.61 9.4 8.5 0.46 9.8 1.1 2.7 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF1732 PF08340.6 KPI43196.1 - 0.77 9.6 5.4 0.92 9.3 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1732) V_ATPase_I PF01496.14 KPI43196.1 - 0.89 7.3 5.5 1.3 6.8 3.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-Q PF13094.1 KPI43196.1 - 1.2 9.1 27.5 1.1 9.2 0.1 4.1 2 1 2 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.3 KPI43196.1 - 1.7 8.5 27.5 0.66 9.8 3.3 4.4 3 1 2 5 5 4 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KPI43196.1 - 1.8 8.1 17.4 4.1e+02 0.4 12.1 2.8 1 1 0 1 1 1 0 IncA protein COG2 PF06148.6 KPI43196.1 - 1.9 8.3 8.9 8.9 6.1 0.4 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin PF00261.15 KPI43196.1 - 2 7.4 28.7 0.079 12.0 15.3 2.0 2 1 0 2 2 2 0 Tropomyosin Reo_sigmaC PF04582.7 KPI43196.1 - 2.3 7.3 13.0 5.3 6.1 8.9 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF812 PF05667.6 KPI43196.1 - 2.7 6.4 18.8 1.4 7.3 11.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF812) ATG16 PF08614.6 KPI43196.1 - 2.9 7.6 24.8 6 6.6 3.2 3.5 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) DivIC PF04977.10 KPI43196.1 - 3.1 7.3 12.2 13 5.3 0.4 4.2 3 1 1 4 4 4 0 Septum formation initiator TBPIP PF07106.8 KPI43196.1 - 4.6 6.7 19.5 1.3 8.5 3.6 3.5 2 1 3 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 KPI43196.1 - 5 5.4 11.5 0.81 8.0 2.4 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF342) DUF1192 PF06698.6 KPI43196.1 - 6.7 6.6 10.3 1 9.2 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Laminin_II PF06009.7 KPI43196.1 - 9.1 6.0 15.3 11 5.7 2.9 2.9 2 1 1 3 3 2 0 Laminin Domain II ADIP PF11559.3 KPI43196.1 - 9.7 6.0 30.4 0.51 10.2 5.2 3.4 2 1 2 4 4 3 0 Afadin- and alpha -actinin-Binding Aldo_ket_red PF00248.16 KPI43197.1 - 5.9e-13 48.2 0.0 8.7e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MMR_HSR1 PF01926.18 KPI43200.1 - 2.9e-06 27.2 0.0 7.4e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase S_layer_C PF05124.7 KPI43201.1 - 0.16 11.5 0.0 7.2 6.1 0.0 2.1 2 0 0 2 2 2 0 S-layer like family, C-terminal region Ribonuc_L-PSP PF01042.16 KPI43202.1 - 2e-25 88.8 0.0 2.7e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP FCH PF00611.18 KPI43203.1 - 6.8e-22 77.4 2.1 2.2e-21 75.8 0.0 2.6 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KPI43203.1 - 6.8e-16 57.5 0.2 5.6e-08 32.2 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KPI43203.1 - 1.7e-15 56.0 0.2 3e-07 29.7 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 KPI43203.1 - 5.1e-13 48.5 5.4 9.7e-13 47.6 3.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 KPI43203.1 - 0.0002 20.7 0.1 0.034 13.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 KPI43203.1 - 0.00059 19.9 0.1 0.018 15.2 0.0 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain C1_2 PF03107.11 KPI43203.1 - 0.79 9.8 7.1 1.3 9.1 4.9 1.4 1 0 0 1 1 1 0 C1 domain Maf1 PF09174.5 KPI43204.1 - 6.7e-57 192.2 0.0 1e-56 191.6 0.0 1.3 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.15 KPI43204.1 - 8.5e-47 158.4 0.2 1.3e-46 157.8 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DSPc PF00782.15 KPI43205.1 - 1.2e-10 41.0 0.2 2.5e-10 40.0 0.1 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KPI43205.1 - 0.045 13.0 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Hemerythrin PF01814.18 KPI43206.1 - 5.1e-09 36.3 0.3 8e-09 35.7 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain GDPD PF03009.12 KPI43207.1 - 6e-37 127.5 0.0 7.7e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.14 KPI43208.1 - 6.6e-59 197.5 0.0 1.2e-58 196.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KPI43208.1 - 1.6e-34 118.3 1.3 1e-33 115.8 0.0 2.4 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KPI43208.1 - 0.00029 20.8 0.0 0.0034 17.3 0.0 2.5 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.27 KPI43208.1 - 0.0062 15.7 0.0 0.013 14.7 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KPI43208.1 - 0.0095 16.0 0.2 0.032 14.3 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.1 KPI43208.1 - 0.013 15.1 0.1 0.028 14.0 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 KPI43208.1 - 0.14 12.0 0.1 0.94 9.5 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain SH3BGR PF04908.10 KPI43209.1 - 0.0022 17.8 0.0 0.0072 16.2 0.0 1.9 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein MFS_1 PF07690.11 KPI43210.1 - 3.6e-32 111.4 31.3 8.3e-32 110.2 21.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MBOAT_2 PF13813.1 KPI43211.1 - 1.3e-09 37.9 1.4 3e-09 36.8 1.0 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Glu-tRNAGln PF02686.10 KPI43212.1 - 0.0072 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Peptidase_C14 PF00656.17 KPI43214.1 - 2e-44 152.1 0.0 3.4e-44 151.4 0.0 1.3 1 1 0 1 1 1 1 Caspase domain PH_4 PF15404.1 KPI43215.1 - 4.5e-50 169.7 0.1 7.4e-49 165.7 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.1 KPI43215.1 - 6.1e-21 73.6 0.2 1.5e-20 72.4 0.2 1.7 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 KPI43215.1 - 1.3e-06 28.5 2.5 0.0001 22.4 0.0 4.0 4 1 0 4 4 4 1 PH domain PH_6 PF15406.1 KPI43215.1 - 0.077 13.0 0.0 2.6 8.1 0.0 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain Abhydrolase_6 PF12697.2 KPI43218.1 - 2.6e-20 73.3 4.1 4.2e-20 72.6 2.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI43218.1 - 4e-07 29.9 0.1 8.4e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KPI43218.1 - 0.00096 18.7 0.1 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_8 PF06259.7 KPI43218.1 - 0.014 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_1 PF00561.15 KPI43218.1 - 0.042 13.3 0.0 0.62 9.5 0.0 2.5 3 0 0 3 3 3 0 alpha/beta hydrolase fold DUF900 PF05990.7 KPI43218.1 - 0.052 12.8 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DIOX_N PF14226.1 KPI43219.1 - 8.5e-30 103.6 0.0 1.4e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI43219.1 - 1.9e-20 73.0 0.0 3.4e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 KPI43220.1 - 2.2e-55 187.5 0.0 3.4e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI43220.1 - 7.9e-20 71.0 0.0 1.5e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KPI43220.1 - 0.026 14.2 1.2 0.2 11.3 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KPI43220.1 - 0.1 12.1 0.4 0.22 11.0 0.2 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 KPI43220.1 - 0.2 10.9 0.1 0.38 10.0 0.1 1.4 1 0 0 1 1 1 0 RIO1 family DLIC PF05783.6 KPI43221.1 - 0.57 8.7 5.5 2.1 6.9 3.8 1.9 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) GMC_oxred_N PF00732.14 KPI43222.1 - 2e-41 142.0 0.0 7e-23 81.2 0.0 2.3 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI43222.1 - 4.6e-28 98.3 0.0 9.9e-28 97.2 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KPI43222.1 - 7.7e-06 25.8 0.0 0.00023 21.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KPI43222.1 - 0.00024 20.1 0.0 0.00035 19.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KPI43222.1 - 0.00063 18.7 0.0 0.0016 17.4 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KPI43222.1 - 0.032 12.8 0.0 0.046 12.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.19 KPI43222.1 - 0.053 12.3 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KPI43222.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.6 KPI43223.1 - 4.3e-24 85.2 0.0 1.4e-23 83.5 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF2359 PF10151.4 KPI43224.1 - 0.014 13.9 0.0 0.019 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2359) DUF4238 PF14022.1 KPI43225.1 - 6e-28 97.8 0.0 1e-27 97.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Pkinase PF00069.20 KPI43226.1 - 6.1e-72 241.8 0.0 7.6e-72 241.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI43226.1 - 1.5e-31 109.4 0.0 2e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KPI43226.1 - 2.1e-05 23.6 0.0 7.4e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KPI43226.1 - 0.00018 20.5 0.0 0.024 13.5 0.0 2.2 1 1 0 2 2 2 2 Kinase-like APH PF01636.18 KPI43226.1 - 0.00034 20.4 0.1 0.0011 18.7 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KPI43226.1 - 0.032 13.5 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Sex_peptide PF08138.6 KPI43227.1 - 0.18 11.6 1.0 0.19 11.5 0.7 1.1 1 0 0 1 1 1 0 Sex peptide (SP) family Ofd1_CTDD PF10637.4 KPI43228.1 - 5.3e-81 271.6 0.0 3.9e-73 245.8 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KPI43228.1 - 3.5e-15 56.3 2.3 1.9e-14 54.0 0.0 3.1 3 2 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KPI43228.1 - 0.017 14.7 0.0 0.074 12.7 0.0 2.2 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily NmrA PF05368.8 KPI43229.1 - 7.7e-14 51.5 0.0 1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI43229.1 - 5.5e-05 23.2 3.7 0.00034 20.6 2.5 2.1 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KPI43229.1 - 0.06 12.2 0.1 1 8.1 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Pkinase PF00069.20 KPI43230.1 - 9e-63 211.8 0.0 1.4e-62 211.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI43230.1 - 2.4e-31 108.7 0.0 1.1e-30 106.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI43230.1 - 3.6e-05 22.8 0.0 6.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KPI43230.1 - 0.0061 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KPI43230.1 - 0.091 12.4 0.0 0.091 12.4 0.0 2.8 2 1 0 3 3 3 0 Phosphotransferase enzyme family Borrelia_P83 PF05262.6 KPI43230.1 - 0.77 7.9 3.8 1.4 7.1 2.6 1.3 1 1 0 1 1 1 0 Borrelia P83/100 protein TMPIT PF07851.8 KPI43231.1 - 5.8 5.8 5.8 9.5 5.1 4.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Uds1 PF15456.1 KPI43232.1 - 0.032 14.2 0.8 0.047 13.6 0.5 1.2 1 0 0 1 1 1 0 Up-regulated During Septation Sugarporin_N PF11471.3 KPI43232.1 - 0.082 12.5 3.2 0.15 11.7 2.2 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Filament PF00038.16 KPI43232.1 - 0.14 11.5 3.4 0.17 11.3 2.1 1.4 1 1 0 1 1 1 0 Intermediate filament protein Sulfotransfer_3 PF13469.1 KPI43233.1 - 0.0075 17.2 0.1 0.0096 16.8 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family DUF663 PF04950.7 KPI43237.1 - 3e-92 308.7 0.0 3e-92 308.7 0.0 1.9 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KPI43237.1 - 8.5e-28 95.7 0.0 2.3e-27 94.3 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KPI43237.1 - 2.9e-07 30.1 0.0 6.6e-05 22.4 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KPI43237.1 - 2.1e-05 24.6 0.1 7.1e-05 22.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KPI43237.1 - 0.0001 22.3 0.0 0.00032 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 KPI43237.1 - 0.00018 21.2 0.1 0.00045 19.9 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 KPI43237.1 - 0.00027 21.1 0.0 0.00072 19.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KPI43237.1 - 0.00034 21.3 0.0 0.00034 21.3 0.0 4.0 3 1 0 3 3 2 1 AAA domain Miro PF08477.8 KPI43237.1 - 0.00047 20.6 0.4 0.0017 18.8 0.0 2.1 2 0 0 2 2 1 1 Miro-like protein MMR_HSR1 PF01926.18 KPI43237.1 - 0.00048 20.0 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KPI43237.1 - 0.00063 19.6 0.0 0.0024 17.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KPI43237.1 - 0.00093 18.7 0.0 0.006 16.0 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 KPI43237.1 - 0.0015 18.2 0.0 0.0036 16.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 KPI43237.1 - 0.0031 17.1 0.1 0.0082 15.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KPI43237.1 - 0.0052 15.6 0.1 0.018 13.8 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.22 KPI43237.1 - 0.0068 16.7 0.0 0.0068 16.7 0.0 2.6 3 0 0 3 3 2 1 ABC transporter AAA_14 PF13173.1 KPI43237.1 - 0.0081 16.0 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KPI43237.1 - 0.0095 15.1 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KPI43237.1 - 0.012 15.3 0.2 0.022 14.4 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.1 KPI43237.1 - 0.012 15.3 0.1 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 KPI43237.1 - 0.013 14.8 0.0 0.036 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KPI43237.1 - 0.016 15.3 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 KPI43237.1 - 0.018 14.7 2.5 0.023 14.4 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 KPI43237.1 - 0.019 15.2 0.0 0.019 15.2 0.0 3.6 3 1 1 4 4 3 0 AAA domain cobW PF02492.14 KPI43237.1 - 0.021 14.2 0.1 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 KPI43237.1 - 0.045 13.4 0.1 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 KPI43237.1 - 0.069 12.1 0.7 0.14 11.1 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain ATP_bind_1 PF03029.12 KPI43237.1 - 0.12 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 KPI43237.1 - 0.26 10.0 0.0 0.26 10.0 0.0 1.8 2 0 0 2 2 2 0 ArgK protein Adeno_IVa2 PF02456.10 KPI43237.1 - 0.3 9.6 0.0 0.49 8.9 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_11 PF13086.1 KPI43237.1 - 0.63 9.5 0.0 0.63 9.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain FTA4 PF13093.1 KPI43238.1 - 8.2e-45 152.8 8.3 1.1e-44 152.4 5.7 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Sugar_tr PF00083.19 KPI43239.1 - 3.7e-97 325.7 22.8 4.3e-97 325.5 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI43239.1 - 4.8e-26 91.2 20.0 4.8e-26 91.2 13.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KPI43239.1 - 0.0003 18.9 0.6 0.00072 17.7 0.4 1.6 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 KPI43239.1 - 0.0028 15.8 0.9 0.0028 15.8 0.6 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.2 KPI43239.1 - 0.0029 17.3 2.0 0.48 10.2 0.0 2.8 2 0 0 2 2 2 2 MFS_1 like family OTT_1508_deam PF14441.1 KPI43240.1 - 1.4e-11 44.3 0.0 2.8e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Cyclin_N PF00134.18 KPI43241.1 - 1.4e-07 31.1 0.0 1.4e-07 31.1 0.0 2.0 3 0 0 3 3 3 1 Cyclin, N-terminal domain Hpt PF01627.18 KPI43242.1 - 1.5e-10 40.9 0.0 2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Hpt domain La PF05383.12 KPI43243.1 - 1.1e-17 63.5 0.0 1.7e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 KPI43243.1 - 1.2e-07 31.6 0.0 2.9e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KPI43243.1 - 6.7e-07 28.8 2.6 1.2e-06 28.0 0.2 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI43243.1 - 0.0055 16.5 0.4 0.033 14.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-H2C2_2 PF13465.1 KPI43245.1 - 1.6e-18 65.9 29.4 2.6e-06 27.4 1.0 5.7 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 KPI43245.1 - 4.2e-12 45.6 41.6 7.7e-05 22.8 1.4 5.8 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI43245.1 - 4.8e-09 35.9 31.3 0.00064 19.8 0.7 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KPI43245.1 - 6e-07 29.4 5.2 0.25 11.5 0.0 4.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KPI43245.1 - 0.0008 19.5 12.9 0.21 11.8 0.0 5.1 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-TRAF PF02176.13 KPI43245.1 - 0.0073 16.6 8.1 0.055 13.8 1.4 2.8 2 0 0 2 2 2 1 TRAF-type zinc finger XPA_N PF01286.13 KPI43245.1 - 7.8 6.2 6.2 0.75 9.5 0.3 2.3 3 0 0 3 3 3 0 XPA protein N-terminal Exo_endo_phos PF03372.18 KPI43246.1 - 4.1e-15 56.3 0.1 6.2e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KPI43246.1 - 3.6e-13 49.1 0.1 1.6e-12 47.1 0.0 2.2 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 KPI43246.1 - 0.00091 19.1 4.5 0.0023 17.8 3.1 1.7 1 0 0 1 1 1 1 GRF zinc finger TFIIA PF03153.8 KPI43246.1 - 0.051 13.4 3.4 0.074 12.9 2.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fungal_trans PF04082.13 KPI43249.1 - 8.3e-38 129.7 0.6 8.3e-38 129.7 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain SET PF00856.23 KPI43249.1 - 0.0014 18.9 0.0 0.0048 17.2 0.0 2.0 2 0 0 2 2 2 1 SET domain HMG_box PF00505.14 KPI43250.1 - 5.2e-22 77.8 0.5 5.2e-22 77.8 0.3 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KPI43250.1 - 2.2e-06 27.9 0.4 4.4e-06 26.9 0.3 1.5 1 0 0 1 1 1 1 HMG-box domain DUF1014 PF06244.7 KPI43250.1 - 0.0023 18.1 0.1 0.0023 18.1 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1014) MAT_Alpha1 PF04769.7 KPI43250.1 - 0.035 13.4 0.3 0.081 12.2 0.2 1.6 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 Pkinase PF00069.20 KPI43251.1 - 6.3e-06 25.5 0.0 1.8e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KPI43251.1 - 0.00096 18.2 0.0 0.014 14.4 0.0 2.6 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KPI43251.1 - 0.0072 16.0 0.2 0.12 12.0 0.0 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KPI43251.1 - 0.054 12.5 0.0 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase RIO1 PF01163.17 KPI43251.1 - 0.094 12.0 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Fructosamin_kin PF03881.9 KPI43251.1 - 0.12 11.3 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase TIM21 PF08294.6 KPI43252.1 - 1e-33 116.0 0.0 1.4e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 KPI43252.1 - 0.00012 21.5 0.0 0.00057 19.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 RAP1 PF07218.6 KPI43253.1 - 0.69 7.9 10.1 0.78 7.7 7.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Shikimate_dh_N PF08501.6 KPI43254.1 - 8.5e-22 77.0 0.2 1.4e-21 76.2 0.2 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KPI43254.1 - 1.7e-13 50.8 0.0 2.7e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KPI43254.1 - 0.0019 18.5 0.1 0.0034 17.7 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 KPI43254.1 - 0.0033 16.2 0.0 0.004 15.9 0.0 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family CPSase_L_chain PF00289.17 KPI43254.1 - 0.059 13.4 0.1 2.9 8.0 0.2 2.2 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain GFO_IDH_MocA PF01408.17 KPI43254.1 - 0.072 13.6 0.1 0.18 12.3 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold TGT_C1 PF14809.1 KPI43254.1 - 0.078 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 C1 domain of tRNA-guanine transglycosylase dimerisation Saccharop_dh PF03435.13 KPI43254.1 - 0.096 11.6 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Slu7 PF11708.3 KPI43255.1 - 7.8e-58 196.0 10.9 7.8e-58 196.0 7.5 2.7 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 KPI43255.1 - 0.024 14.3 0.8 0.044 13.4 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle SUN PF03856.8 KPI43256.1 - 1.1e-65 221.3 11.7 3.1e-65 219.9 8.1 1.6 1 1 0 1 1 1 1 Beta-glucosidase (SUN family) Mito_fiss_reg PF05308.6 KPI43256.1 - 0.02 14.2 1.9 0.036 13.4 1.3 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator MIF4G PF02854.14 KPI43257.1 - 1.1e-58 198.1 5.4 1e-29 103.4 0.1 3.6 4 0 0 4 4 4 2 MIF4G domain Upf2 PF04050.9 KPI43257.1 - 1.6e-50 171.2 17.2 4.2e-50 169.8 11.9 1.7 1 0 0 1 1 1 1 Up-frameshift suppressor 2 FliD_C PF07195.7 KPI43257.1 - 0.0035 16.6 2.0 0.13 11.5 0.1 2.5 2 0 0 2 2 2 2 Flagellar hook-associated protein 2 C-terminus BOP1NT PF08145.7 KPI43258.1 - 0.12 12.1 0.1 0.31 10.7 0.0 1.6 2 0 0 2 2 2 0 BOP1NT (NUC169) domain Hydrolase_6 PF13344.1 KPI43259.1 - 9.2e-23 80.0 0.0 2.1e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KPI43259.1 - 4.8e-12 45.4 0.0 4.6e-11 42.2 0.0 2.7 3 1 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.1 KPI43259.1 - 0.0097 16.1 0.0 3.3 7.9 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase rRNA_processing PF08524.6 KPI43261.1 - 0.0022 17.7 2.3 0.0022 17.7 1.6 2.3 2 0 0 2 2 2 2 rRNA processing XRCC4 PF06632.7 KPI43261.1 - 1.9 7.2 12.1 2.3 7.0 8.4 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Hamartin PF04388.7 KPI43261.1 - 3.7 6.0 6.8 5.5 5.5 4.7 1.3 1 1 0 1 1 1 0 Hamartin protein IncA PF04156.9 KPI43263.1 - 0.0058 16.2 0.0 0.0074 15.9 0.0 1.1 1 0 0 1 1 1 1 IncA protein Shisa PF13908.1 KPI43263.1 - 0.01 15.9 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 KPI43263.1 - 0.025 12.8 0.0 0.027 12.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4448 PF14610.1 KPI43263.1 - 0.025 14.0 0.0 0.03 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4190 PF13828.1 KPI43263.1 - 0.027 14.0 1.6 0.042 13.3 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) CD34_antigen PF06365.7 KPI43263.1 - 0.035 13.7 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family FAM176 PF14851.1 KPI43263.1 - 0.037 13.7 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 FAM176 family HemY_N PF07219.8 KPI43263.1 - 0.038 13.5 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 HemY protein N-terminus DUF1049 PF06305.6 KPI43263.1 - 0.21 11.0 0.7 0.59 9.6 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) Consortin_C PF15281.1 KPI43263.1 - 7.9 6.0 7.3 8.4 5.9 4.4 1.5 1 1 0 1 1 1 0 Consortin C-terminus F-box-like PF12937.2 KPI43264.1 - 1.1e-05 25.0 0.1 1.1e-05 25.0 0.0 2.5 4 0 0 4 4 4 1 F-box-like F-box PF00646.28 KPI43264.1 - 0.024 14.3 1.5 0.4 10.4 1.2 3.0 2 1 0 2 2 2 0 F-box domain LRR_6 PF13516.1 KPI43264.1 - 0.033 14.2 2.6 2.7 8.3 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.2 KPI43264.1 - 0.05 13.2 1.7 0.25 11.0 0.4 2.7 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KPI43264.1 - 0.058 13.1 5.3 0.22 11.2 0.5 3.9 5 1 0 6 6 6 0 Leucine rich repeat LRR_7 PF13504.1 KPI43264.1 - 7.7 7.2 5.6 1.5e+02 3.3 0.0 4.2 4 0 0 4 4 4 0 Leucine rich repeat Sugar_tr PF00083.19 KPI43265.1 - 2.5e-58 197.7 29.9 1.7e-47 162.0 11.0 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.13 KPI43265.1 - 9.8e-20 70.5 0.8 6e-14 51.5 0.0 2.5 1 1 1 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.11 KPI43265.1 - 1.7e-13 50.0 21.6 1.7e-13 50.0 15.0 3.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Ribosomal_L14e PF01929.12 KPI43266.1 - 2.9e-22 78.8 2.3 2.9e-22 78.8 1.6 1.4 1 1 0 1 1 1 1 Ribosomal protein L14 Nitr_red_assoc PF09655.5 KPI43266.1 - 0.041 14.2 0.6 0.054 13.8 0.4 1.2 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) rRNA_proc-arch PF13234.1 KPI43266.1 - 0.23 10.5 4.7 0.88 8.6 0.0 2.1 2 0 0 2 2 2 0 rRNA-processing arch domain PPI_Ypi1 PF07491.6 KPI43267.1 - 2.4e-23 81.5 0.1 4.8e-23 80.5 0.1 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor GCS PF03074.11 KPI43268.1 - 3.3e-152 506.8 0.0 8.3e-152 505.5 0.0 1.6 1 1 0 1 1 1 1 Glutamate-cysteine ligase UPF0278 PF08745.6 KPI43268.1 - 0.038 13.2 0.0 0.083 12.1 0.0 1.5 1 0 0 1 1 1 0 UPF0278 family MFS_1 PF07690.11 KPI43269.1 - 1.5e-26 92.9 29.6 2.1e-26 92.4 20.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TatD_DNase PF01026.16 KPI43270.1 - 1.7e-35 122.4 0.0 3.6e-35 121.4 0.0 1.5 1 1 0 1 1 1 1 TatD related DNase MCM PF00493.18 KPI43272.1 - 1.8e-51 174.9 0.0 3e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 KPI43272.1 - 6.3e-37 126.9 40.3 6.3e-37 126.9 27.9 1.8 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KPI43272.1 - 5.4e-20 72.0 0.1 1e-19 71.2 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.9 KPI43272.1 - 0.0014 18.3 0.1 0.0036 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF1272 PF06906.6 KPI43272.1 - 0.0085 15.9 0.6 0.017 14.9 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) FAM92 PF06730.6 KPI43272.1 - 0.032 13.5 3.0 0.055 12.7 2.0 1.3 1 0 0 1 1 1 0 FAM92 protein DUF164 PF02591.10 KPI43272.1 - 0.043 13.6 0.4 0.12 12.2 0.2 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain CsbD PF05532.7 KPI43273.1 - 1.6e-09 37.2 17.1 2.4e-09 36.7 3.3 3.1 2 1 1 3 3 3 2 CsbD-like Pmp3 PF01679.12 KPI43274.1 - 4.9e-27 93.3 5.5 5.4e-27 93.2 3.8 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 KPI43274.1 - 0.064 12.9 2.7 0.064 12.9 1.8 1.9 2 0 0 2 2 2 0 Conserved TM helix GMC_oxred_N PF00732.14 KPI43275.1 - 3.5e-58 197.0 0.0 4.7e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI43275.1 - 2.5e-17 63.5 0.3 7.9e-11 42.4 0.0 2.4 1 1 1 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 KPI43275.1 - 7.4e-07 28.3 0.7 0.017 13.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KPI43275.1 - 1.2e-05 24.3 1.4 0.0009 18.2 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI43275.1 - 0.00062 19.7 0.1 0.18 11.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI43275.1 - 0.001 18.0 0.1 0.0017 17.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KPI43275.1 - 0.006 16.5 0.1 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KPI43275.1 - 0.0076 15.3 0.5 0.022 13.8 0.0 2.0 3 0 0 3 3 3 1 Thi4 family Pyr_redox_3 PF13738.1 KPI43275.1 - 0.029 14.4 1.0 5.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCM2_N PF12619.3 KPI43276.1 - 7.6 6.4 18.2 0.089 12.7 5.5 2.5 2 1 0 2 2 2 0 Mini-chromosome maintenance protein 2 DUF1996 PF09362.5 KPI43277.1 - 6.1e-85 284.6 1.8 8.8e-85 284.0 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 KPI43277.1 - 5.1e-16 58.3 12.5 5.1e-16 58.3 8.6 2.0 2 0 0 2 2 2 1 WSC domain Sulfate_transp PF00916.15 KPI43278.1 - 4.9e-75 252.1 11.3 4.9e-75 252.1 7.9 1.7 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KPI43278.1 - 2.3e-31 107.2 3.2 2.3e-31 107.2 2.2 4.1 7 0 0 7 7 7 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KPI43278.1 - 3e-09 36.3 0.0 6.1e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 KPI43278.1 - 3.2 7.5 9.2 0.089 12.5 1.1 2.4 2 0 0 2 2 2 0 Stannin transmembrane p450 PF00067.17 KPI43279.1 - 2.2e-62 211.0 0.0 2.5e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MR_MLE_C PF13378.1 KPI43280.1 - 5e-18 65.1 0.0 9.4e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KPI43280.1 - 4.2e-15 55.7 0.0 8.3e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 KPI43280.1 - 2.3e-08 34.4 0.0 5e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain HET PF06985.6 KPI43281.1 - 1.5e-15 57.5 0.0 3.5e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GLTP PF08718.6 KPI43282.1 - 6.9e-41 139.7 0.1 1.5e-40 138.6 0.0 1.5 1 1 0 1 1 1 1 Glycolipid transfer protein (GLTP) MFS_1 PF07690.11 KPI43283.1 - 1.7e-30 105.9 16.6 2.6e-30 105.3 11.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily 2OG-FeII_Oxy PF03171.15 KPI43283.1 - 7.1e-21 74.3 0.0 1.6e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KPI43283.1 - 3.8e-19 69.3 0.0 7.8e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DENN PF02141.16 KPI43284.1 - 4.1e-51 173.3 0.2 7.9e-51 172.4 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KPI43284.1 - 4.5e-12 45.7 0.0 9.8e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 KPI43284.1 - 0.00087 19.3 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 dDENN domain Bac_rhamnosid PF05592.6 KPI43285.1 - 3.6e-165 550.0 0.0 4.5e-165 549.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KPI43285.1 - 1.1e-40 138.9 0.0 2.2e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain DUF3475 PF11961.3 KPI43285.1 - 0.086 12.6 0.4 0.24 11.2 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3475) SE PF08491.5 KPI43285.1 - 0.26 10.0 0.0 1.2 7.9 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Thiolase_N PF00108.18 KPI43286.1 - 5.1e-66 222.3 0.1 8.9e-66 221.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KPI43286.1 - 1.2e-35 121.5 0.7 1.2e-35 121.5 0.5 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KPI43286.1 - 0.044 13.2 0.9 0.092 12.2 0.3 1.8 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KPI43286.1 - 0.052 13.2 0.2 4.5 6.9 0.0 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF3115 PF11312.3 KPI43287.1 - 2.2e-92 309.2 0.0 2.8e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) DGF-1_C PF11040.3 KPI43289.1 - 1.3 8.9 3.6 2.1 8.3 1.5 2.2 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus G-alpha PF00503.15 KPI43290.1 - 9.1e-128 426.2 0.6 1.1e-127 425.9 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KPI43290.1 - 2.6e-15 56.0 0.8 1.8e-10 40.3 0.2 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KPI43290.1 - 4.3e-05 22.7 0.2 0.22 10.6 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KPI43290.1 - 0.0011 19.3 0.1 0.61 10.5 0.0 2.7 3 0 0 3 3 3 2 Miro-like protein GTP_EFTU PF00009.22 KPI43290.1 - 0.034 13.5 0.0 4.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ApoC-I PF04691.7 KPI43290.1 - 0.036 13.7 0.4 0.16 11.6 0.0 2.2 2 1 1 3 3 3 0 Apolipoprotein C-I (ApoC-1) AAA_29 PF13555.1 KPI43290.1 - 0.049 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FAD_binding_3 PF01494.14 KPI43291.1 - 2.3e-13 49.9 0.2 2.3e-12 46.6 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI43291.1 - 4e-12 45.7 1.0 9.2e-06 24.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KPI43291.1 - 8.5e-08 32.5 0.0 1.5e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI43291.1 - 2.1e-07 30.8 0.3 5.2e-07 29.5 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI43291.1 - 0.00013 21.0 1.0 0.0002 20.3 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KPI43291.1 - 0.0003 19.9 0.0 0.00067 18.8 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KPI43291.1 - 0.00041 18.9 0.3 0.0053 15.2 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.9 KPI43291.1 - 0.0019 16.9 0.1 0.2 10.2 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 KPI43291.1 - 0.0038 16.1 0.4 0.0054 15.6 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KPI43291.1 - 0.0061 16.9 0.0 0.62 10.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI43291.1 - 0.014 15.2 0.3 0.031 14.1 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KPI43291.1 - 0.017 14.7 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KPI43291.1 - 0.033 13.7 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.19 KPI43291.1 - 0.05 12.6 0.4 0.09 11.8 0.3 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.9 KPI43291.1 - 0.13 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 KPI43291.1 - 0.27 11.2 1.9 7.8 6.4 0.3 2.2 2 0 0 2 2 2 0 NADH(P)-binding Ribosomal_S13_N PF08069.7 KPI43292.1 - 4.2e-27 93.7 0.1 8.2e-27 92.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KPI43292.1 - 1.8e-21 75.6 0.0 2.7e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 KPI43292.1 - 0.026 14.2 0.1 0.045 13.4 0.0 1.6 1 1 0 1 1 1 0 'Paired box' domain CENP-N PF05238.8 KPI43293.1 - 2.8e-64 217.6 0.0 3.4e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Pro-rich PF15240.1 KPI43294.1 - 0.042 13.9 21.5 0.052 13.6 14.9 1.1 1 0 0 1 1 1 0 Proline-rich Aminotran_5 PF00266.14 KPI43295.1 - 9.6e-95 317.4 0.0 1.2e-94 317.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KPI43295.1 - 1.8e-07 30.5 0.0 4.4e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KPI43295.1 - 6.6e-07 28.5 0.0 9.8e-07 28.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KPI43295.1 - 0.00011 21.4 0.0 0.00039 19.5 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family PEP_mutase PF13714.1 KPI43296.1 - 1.8e-61 207.4 0.2 2.5e-61 206.9 0.1 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KPI43296.1 - 7.5e-10 37.6 0.2 1.2e-09 36.9 0.1 1.3 1 1 0 1 1 1 1 Isocitrate lyase family SBP_bac_5 PF00496.17 KPI43297.1 - 0.064 12.0 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Mito_fiss_reg PF05308.6 KPI43297.1 - 0.12 11.6 8.0 0.12 11.6 5.3 1.3 1 1 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KPI43297.1 - 0.15 11.2 3.6 0.22 10.7 2.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Clat_adaptor_s PF01217.15 KPI43299.1 - 2.6e-42 143.9 0.0 4.2e-42 143.2 0.0 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Bromodomain PF00439.20 KPI43300.1 - 1.2e-12 47.5 0.0 4e-12 45.8 0.0 1.9 1 1 0 1 1 1 1 Bromodomain Sigma70_ner PF04546.8 KPI43300.1 - 0.27 10.8 12.2 0.21 11.2 3.3 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region MFS_1 PF07690.11 KPI43301.1 - 9.8e-27 93.5 26.8 1.4e-25 89.7 12.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI43301.1 - 4.5e-11 41.9 13.7 5e-11 41.8 3.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KPI43301.1 - 0.0035 15.8 15.0 0.0064 14.9 1.2 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein Fungal_trans PF04082.13 KPI43302.1 - 2e-21 76.0 3.6 3.5e-21 75.2 2.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI43302.1 - 4.2e-06 26.5 11.9 6.1e-06 26.0 7.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.10 KPI43303.1 - 7.6e-13 48.0 14.0 1.3e-12 47.3 9.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KPI43303.1 - 1.3e-07 31.4 10.4 2.5e-07 30.5 7.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor Herpes_BLRF2 PF05812.7 KPI43303.1 - 0.00036 20.3 0.4 0.00036 20.3 0.3 2.1 1 1 0 2 2 2 1 Herpesvirus BLRF2 protein TSC22 PF01166.13 KPI43303.1 - 0.06 13.3 1.0 0.13 12.2 0.7 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Adeno_PIX PF03955.9 KPI43303.1 - 0.11 12.9 0.9 0.2 12.1 0.7 1.4 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Atg14 PF10186.4 KPI43303.1 - 0.38 9.6 10.0 0.51 9.2 6.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 KPI43303.1 - 0.55 8.0 6.5 0.69 7.7 4.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4094 PF13334.1 KPI43303.1 - 0.6 10.5 3.7 1.3 9.4 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) bZIP_Maf PF03131.12 KPI43303.1 - 1.7 8.9 14.6 0.19 12.0 5.7 2.2 1 1 1 2 2 2 0 bZIP Maf transcription factor IncA PF04156.9 KPI43303.1 - 2 7.9 10.5 2.8 7.5 7.2 1.1 1 0 0 1 1 1 0 IncA protein Glyco_trans_1_2 PF13524.1 KPI43303.1 - 2.1 8.6 4.8 1.7 8.9 0.2 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 APG6 PF04111.7 KPI43303.1 - 5.9 5.8 10.5 8.7 5.2 7.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 KPI43303.1 - 6.3 6.8 13.3 2.5 8.1 5.4 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Birna_RdRp PF04197.7 KPI43303.1 - 6.8 4.5 10.1 4 5.3 6.2 1.3 1 1 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) PTS_IIA PF02255.11 KPI43304.1 - 0.14 12.0 2.0 0.15 11.9 0.4 1.8 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit SDA1 PF05285.7 KPI43304.1 - 0.23 10.6 10.8 0.38 9.9 7.5 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 KPI43304.1 - 0.31 8.8 11.6 0.36 8.7 8.0 1.1 1 0 0 1 1 1 0 Nop14-like family Mak16 PF04874.9 KPI43304.1 - 0.64 10.1 12.3 1.2 9.2 8.6 1.5 1 0 0 1 1 1 0 Mak16 protein C-terminal region BUD22 PF09073.5 KPI43304.1 - 1.7 7.6 18.5 2.6 7.0 12.7 1.4 1 1 0 1 1 1 0 BUD22 ANTH PF07651.11 KPI43305.1 - 9e-77 257.5 0.0 9e-77 257.5 0.0 3.1 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.12 KPI43305.1 - 7.4e-63 211.0 5.9 7.4e-63 211.0 4.1 5.7 5 1 0 6 6 6 1 I/LWEQ domain ENTH PF01417.15 KPI43305.1 - 6.6e-05 22.7 0.2 0.00045 20.0 0.0 2.7 2 0 0 2 2 2 1 ENTH domain OST-HTH PF12872.2 KPI43305.1 - 0.08 12.7 0.5 2.4 8.0 0.1 2.9 3 0 0 3 3 3 0 OST-HTH/LOTUS domain TcdB_N PF12918.2 KPI43305.1 - 0.6 10.2 7.4 0.075 13.1 1.0 2.8 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Med15 PF09606.5 KPI43305.1 - 5 5.1 39.8 9.8 4.2 27.6 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Sec62 PF03839.11 KPI43306.1 - 2e-51 174.5 1.8 2e-51 174.5 1.3 2.1 1 1 0 2 2 2 1 Translocation protein Sec62 SinI PF08671.5 KPI43306.1 - 0.0075 15.6 0.1 0.022 14.2 0.1 1.8 1 0 0 1 1 1 1 Anti-repressor SinI tRNA-synt_1g PF09334.6 KPI43306.1 - 0.15 10.7 3.1 0.23 10.0 2.2 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) Rpp20 PF12328.3 KPI43306.1 - 5.1 6.7 9.5 1.2 8.7 3.4 2.1 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Dicty_REP PF05086.7 KPI43306.1 - 6 4.4 6.3 9.6 3.8 4.4 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AA_permease_2 PF13520.1 KPI43307.1 - 8.5e-57 192.5 50.0 1e-56 192.3 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI43307.1 - 4.8e-26 91.1 41.7 6.5e-26 90.6 28.9 1.1 1 0 0 1 1 1 1 Amino acid permease SGL PF08450.7 KPI43308.1 - 1e-20 74.2 0.0 6.1e-20 71.6 0.0 1.9 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KPI43308.1 - 0.0047 16.8 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Arylesterase NHL PF01436.16 KPI43308.1 - 0.039 13.9 2.3 0.26 11.3 0.0 3.2 3 0 0 3 3 3 0 NHL repeat Str_synth PF03088.11 KPI43308.1 - 0.12 12.4 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Strictosidine synthase DNA_binding_1 PF01035.15 KPI43309.1 - 2.5e-17 62.4 0.0 5.8e-17 61.2 0.0 1.6 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain PHO4 PF01384.15 KPI43310.1 - 1.9e-54 184.5 6.3 2.1e-54 184.3 4.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family YjbE PF11106.3 KPI43310.1 - 0.12 12.3 11.2 2.6 8.0 0.6 3.5 3 0 0 3 3 3 0 Exopolysaccharide production protein YjbE F-box-like_2 PF13013.1 KPI43313.1 - 0.00045 19.9 0.2 1.5 8.5 0.0 3.0 3 0 0 3 3 3 2 F-box-like domain SieB PF14163.1 KPI43314.1 - 4 7.0 8.5 1.9 8.0 4.1 1.7 2 0 0 2 2 2 0 Superinfection exclusion protein B SUR7 PF06687.7 KPI43314.1 - 4.6 6.7 12.9 1.4e+02 1.8 9.0 2.7 1 1 1 2 2 2 0 SUR7/PalI family Fungal_trans_2 PF11951.3 KPI43315.1 - 1.1e-26 93.3 5.7 2.9e-13 49.1 0.3 2.5 2 1 0 3 3 3 2 Fungal specific transcription factor domain Acyl_transf_3 PF01757.17 KPI43315.1 - 2.6e-18 65.9 31.0 6e-18 64.7 21.5 1.6 1 1 0 1 1 1 1 Acyltransferase family Aminotran_5 PF00266.14 KPI43316.1 - 4.4e-23 81.6 0.0 1.1e-22 80.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KPI43316.1 - 6.8e-06 25.2 0.0 1.4e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II SLA_LP_auto_ag PF05889.8 KPI43316.1 - 0.04 12.3 0.0 0.069 11.6 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Pyridoxal_deC PF00282.14 KPI43316.1 - 0.052 11.9 0.0 0.1 11.0 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Glyco_transf_8 PF01501.15 KPI43317.1 - 6.8e-26 91.1 0.0 9.1e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Dynactin PF12455.3 KPI43318.1 - 1.3e-57 194.8 10.2 1.3e-57 194.8 7.1 4.8 4 2 2 6 6 6 1 Dynein associated protein CAP_GLY PF01302.20 KPI43318.1 - 8.8e-22 76.5 0.2 1.7e-21 75.6 0.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain Myosin_tail_1 PF01576.14 KPI43318.1 - 0.0014 16.4 39.5 0.0014 16.4 27.3 3.1 2 1 1 3 3 3 3 Myosin tail IMS PF00817.15 KPI43319.1 - 3e-34 117.9 0.0 4.6e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KPI43319.1 - 4.3e-12 46.0 0.0 7.8e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF3602 PF12223.3 KPI43320.1 - 2.9e-05 24.3 13.4 5.1e-05 23.5 3.5 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) LURAP PF14854.1 KPI43320.1 - 0.055 13.1 0.7 0.14 11.9 0.5 1.6 1 0 0 1 1 1 0 Leucine rich adaptor protein SUI1 PF01253.17 KPI43321.1 - 1.5e-28 98.3 5.2 2.6e-28 97.6 3.6 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 EOS1 PF12326.3 KPI43321.1 - 1.9e-11 43.8 3.2 1.9e-11 43.8 2.2 2.0 3 0 0 3 3 3 1 N-glycosylation protein DUF4131 PF13567.1 KPI43321.1 - 0.062 12.7 2.2 0.081 12.3 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DNA_pol_B PF00136.16 KPI43322.1 - 2.6e-83 280.3 0.0 1.1e-82 278.3 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KPI43322.1 - 2.3e-20 72.7 0.0 7.8e-11 41.4 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KPI43322.1 - 3.4e-17 62.2 4.2 7.2e-17 61.1 2.9 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta AMP-binding PF00501.23 KPI43323.1 - 6.9e-53 179.5 0.0 2.5e-52 177.6 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI43323.1 - 8.1e-07 29.9 0.0 1.7e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.19 KPI43324.1 - 6.9e-62 209.4 20.7 2.3e-59 201.1 14.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI43324.1 - 2.8e-22 78.9 27.9 2.8e-22 78.9 19.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TPK_catalytic PF04263.11 KPI43325.1 - 6.5e-23 80.6 0.0 9.5e-23 80.1 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 KPI43325.1 - 3.7e-19 68.2 0.0 6.2e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Gly-zipper_OmpA PF13436.1 KPI43326.1 - 0.00026 20.6 0.0 0.00059 19.4 0.0 1.6 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Rick_17kDa_Anti PF05433.10 KPI43326.1 - 0.016 14.8 13.0 0.022 14.3 9.0 1.2 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 KPI43326.1 - 0.056 12.9 7.9 0.087 12.3 5.5 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 KPI43326.1 - 2.1 8.0 14.3 3.5 7.3 1.6 1.9 1 1 0 2 2 2 0 Glycine zipper Tcp11 PF05794.8 KPI43328.1 - 1.7e-35 122.5 0.5 4.2e-35 121.3 0.3 1.7 1 0 0 1 1 1 1 T-complex protein 11 IQ PF00612.22 KPI43328.1 - 0.024 14.2 1.6 0.1 12.2 1.1 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF676 PF05057.9 KPI43329.1 - 6e-49 166.2 0.0 9.1e-49 165.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KPI43329.1 - 5.7e-07 29.6 0.1 1.1e-06 28.7 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI43329.1 - 1.9e-06 27.7 0.0 3.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KPI43329.1 - 0.00051 19.7 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 KPI43329.1 - 0.0029 16.7 0.0 0.029 13.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 KPI43329.1 - 0.0083 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 KPI43329.1 - 0.12 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KPI43329.1 - 0.14 11.6 0.1 2.1 7.7 0.1 2.2 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase ADH_zinc_N PF00107.21 KPI43331.1 - 6.2e-26 90.4 0.2 1.2e-25 89.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI43331.1 - 1.7e-06 27.7 0.0 4.3e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KPI43331.1 - 6.4e-05 23.8 0.0 0.00022 22.0 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 KPI43331.1 - 0.22 11.8 2.1 1.5 9.1 0.3 2.2 1 1 0 2 2 2 0 Putative NAD(P)-binding Homeobox PF00046.24 KPI43332.1 - 7.9e-13 47.8 1.1 1.9e-12 46.5 0.8 1.6 1 0 0 1 1 1 1 Homeobox domain UPF0139 PF03669.8 KPI43333.1 - 0.002 17.6 0.1 0.0026 17.2 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Glyco_transf_34 PF05637.7 KPI43334.1 - 3.7e-53 180.4 0.0 8.3e-53 179.3 0.0 1.5 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Ribosomal_S8e PF01201.17 KPI43335.1 - 2.1e-46 157.3 3.0 2.5e-46 157.0 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Shikimate_dh_N PF08501.6 KPI43336.1 - 4.2e-19 68.3 0.0 9.2e-19 67.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KPI43336.1 - 9.9e-13 48.3 0.0 1.5e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KPI43337.1 - 8.9e-18 64.7 0.0 1.3e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI43337.1 - 5.1e-17 62.4 0.0 6.2e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KPI43337.1 - 0.018 13.9 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KPI43337.1 - 0.024 14.6 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding KR PF08659.5 KPI43337.1 - 0.031 13.9 0.0 0.096 12.3 0.0 1.8 1 1 0 1 1 1 0 KR domain GSH_synthase PF03199.10 KPI43337.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic glutathione synthase F-box-like PF12937.2 KPI43338.1 - 0.00095 18.8 0.3 0.0026 17.4 0.0 1.9 2 0 0 2 2 2 1 F-box-like Sugar_tr PF00083.19 KPI43340.1 - 5.7e-37 127.3 31.8 8.5e-35 120.1 22.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI43340.1 - 6.7e-30 103.9 58.3 2.5e-20 72.5 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_trans_2_3 PF13632.1 KPI43340.1 - 8.9 5.9 9.4 0.14 11.8 0.4 2.3 2 1 0 2 2 2 0 Glycosyl transferase family group 2 DUF2390 PF09523.5 KPI43341.1 - 0.66 10.1 5.9 4.7 7.4 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2390) Anp1 PF03452.9 KPI43344.1 - 3.9e-104 347.5 0.0 5e-104 347.2 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 KPI43344.1 - 0.043 13.5 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Tubulin_C PF03953.12 KPI43346.1 - 1.6e-33 115.4 0.1 2e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain COX14 PF14880.1 KPI43347.1 - 3.9e-13 48.8 0.3 3.9e-13 48.8 0.2 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF1180 PF06679.7 KPI43347.1 - 0.037 13.9 0.4 0.073 12.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) F-box-like PF12937.2 KPI43348.1 - 7.1e-06 25.6 0.1 1.5e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KPI43348.1 - 0.0064 16.1 0.7 0.017 14.7 0.1 2.1 2 0 0 2 2 2 1 F-box domain ERO1 PF04137.10 KPI43349.1 - 4.2e-127 424.0 1.5 5.8e-127 423.5 1.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DNase_NucA_NucB PF14040.1 KPI43350.1 - 1.5e-07 31.5 0.0 5.4e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 Deoxyribonuclease NucA/NucB Sel1 PF08238.7 KPI43352.1 - 3e-11 43.5 13.4 0.00055 20.4 0.4 4.2 4 0 0 4 4 4 3 Sel1 repeat SPX PF03105.14 KPI43353.1 - 3.1e-25 89.4 0.8 4.6e-25 88.9 0.1 1.6 2 0 0 2 2 2 1 SPX domain GLE1 PF07817.8 KPI43353.1 - 0.13 11.2 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 GLE1-like protein Val_tRNA-synt_C PF10458.4 KPI43353.1 - 0.19 11.7 0.2 0.19 11.7 0.1 2.1 4 0 0 4 4 4 0 Valyl tRNA synthetase tRNA binding arm AA_permease_2 PF13520.1 KPI43354.1 - 1.2e-44 152.4 58.8 1.3e-42 145.8 40.7 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI43354.1 - 1.6e-13 49.8 51.8 1.1e-09 37.1 17.2 2.1 1 1 1 2 2 2 2 Amino acid permease DUF4210 PF13915.1 KPI43355.1 - 2.1e-24 85.5 0.2 6e-24 84.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 KPI43355.1 - 1.2e-22 79.5 0.1 3.1e-22 78.1 0.1 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis ADK PF00406.17 KPI43356.1 - 1.7e-34 118.8 0.0 1.4e-20 73.6 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 KPI43356.1 - 7.8e-13 47.8 0.0 3e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KPI43356.1 - 0.0012 19.6 0.0 0.0025 18.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KPI43356.1 - 0.0025 18.1 0.0 0.0067 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KPI43356.1 - 0.007 16.2 0.0 0.029 14.2 0.0 2.0 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KPI43356.1 - 0.084 11.9 0.1 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 KPI43356.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain CMV_1a_C PF12503.3 KPI43356.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein C terminal NACHT PF05729.7 KPI43356.1 - 0.13 11.9 0.0 6.8 6.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain DUF3328 PF11807.3 KPI43357.1 - 4.1e-28 98.5 3.2 5.4e-28 98.1 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Atg14 PF10186.4 KPI43358.1 - 0.00033 19.7 5.0 0.00068 18.6 3.5 1.5 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Apc3 PF12895.2 KPI43358.1 - 0.00036 20.6 0.4 1.5 9.0 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 IncA PF04156.9 KPI43358.1 - 0.00037 20.1 0.0 0.00037 20.1 0.0 2.1 3 0 0 3 3 3 1 IncA protein DUF1664 PF07889.7 KPI43358.1 - 0.0017 18.1 0.3 0.0044 16.8 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) OAR PF03826.12 KPI43358.1 - 0.042 13.3 0.9 0.28 10.7 0.1 2.7 3 0 0 3 3 3 0 OAR domain Reo_sigmaC PF04582.7 KPI43358.1 - 0.051 12.7 0.2 0.098 11.8 0.1 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 KPI43358.1 - 0.19 11.5 4.3 0.27 10.9 1.2 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein TPR_19 PF14559.1 KPI43358.1 - 0.19 12.0 13.2 0.25 11.6 0.7 4.4 5 1 1 6 6 6 0 Tetratricopeptide repeat Striatin PF08232.7 KPI43358.1 - 0.32 11.3 6.1 1.3 9.2 4.2 2.2 1 1 0 1 1 1 0 Striatin family CENP-Q PF13094.1 KPI43358.1 - 3.2 7.7 11.1 0.18 11.8 2.5 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit PfkB PF00294.19 KPI43359.1 - 7.9e-08 31.7 0.0 9.2e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phosphorylase PF00343.15 KPI43360.1 - 0 1075.8 0.4 0 1075.6 0.2 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase AAA_35 PF14516.1 KPI43360.1 - 0.072 11.7 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain TPR_11 PF13414.1 KPI43361.1 - 1.8e-16 59.5 3.0 8.2e-09 34.9 0.1 2.8 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 KPI43361.1 - 9.1e-14 50.3 1.3 6.9e-06 25.4 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KPI43361.1 - 2.5e-13 48.8 1.5 0.00022 20.9 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KPI43361.1 - 5.8e-09 35.7 0.2 1.5e-05 24.7 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KPI43361.1 - 4e-07 29.3 0.2 0.049 13.4 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KPI43361.1 - 1.5e-06 27.5 0.0 0.00012 21.6 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KPI43361.1 - 1.9e-06 27.9 0.0 1.9 9.1 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat PB1 PF00564.19 KPI43361.1 - 4.9e-06 26.1 0.1 9.7e-06 25.1 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_17 PF13431.1 KPI43361.1 - 0.00024 21.0 0.1 0.008 16.2 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KPI43361.1 - 0.0027 18.3 2.2 0.011 16.4 0.1 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KPI43361.1 - 0.055 14.1 0.0 1 10.1 0.0 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KPI43361.1 - 0.066 13.0 0.1 3.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Lyase_1 PF00206.15 KPI43362.1 - 4.7e-36 124.5 1.7 1.2e-29 103.5 0.1 2.5 1 1 1 2 2 2 2 Lyase ADSL_C PF10397.4 KPI43362.1 - 1.7e-24 85.5 0.2 2.1e-23 82.0 0.0 2.8 4 0 0 4 4 4 1 Adenylosuccinate lyase C-terminus BRCT PF00533.21 KPI43363.1 - 0.0018 18.3 0.0 0.017 15.2 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain TLV_coat PF00429.14 KPI43363.1 - 0.054 11.9 0.2 0.079 11.4 0.1 1.2 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) V-SNARE PF05008.10 KPI43364.1 - 3.8 7.7 8.0 0.35 11.0 0.7 2.8 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Prefoldin_2 PF01920.15 KPI43364.1 - 6.6 6.5 11.3 0.55 10.0 0.6 3.0 3 0 0 3 3 3 0 Prefoldin subunit Lectin_C PF00059.16 KPI43365.1 - 0.0015 19.1 0.5 0.38 11.4 0.1 2.6 2 0 0 2 2 2 2 Lectin C-type domain TMEM154 PF15102.1 KPI43365.1 - 0.65 9.6 4.0 1.4 8.5 0.0 2.5 3 0 0 3 3 3 0 TMEM154 protein family Glyco_hydro_10 PF00331.15 KPI43367.1 - 6.8e-103 344.0 0.0 8e-103 343.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DSBA PF01323.15 KPI43368.1 - 1.3e-16 60.7 0.1 1.7e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Amidase PF01425.16 KPI43369.1 - 5.8e-38 130.8 1.3 1.7e-37 129.3 0.6 1.7 2 0 0 2 2 2 1 Amidase GST_N_3 PF13417.1 KPI43370.1 - 1.9e-12 47.2 0.0 7e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI43370.1 - 7e-12 45.1 0.0 6e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KPI43370.1 - 8.2e-11 41.7 0.0 1.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI43370.1 - 6.4e-10 38.7 0.0 1.1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KPI43370.1 - 2.4e-09 37.2 0.0 5.5e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KPI43370.1 - 5.1e-05 23.6 0.1 8.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BSP PF04450.7 KPI43371.1 - 3.2e-57 193.3 0.4 1.3e-55 188.0 0.3 2.5 1 1 0 1 1 1 1 Peptidase of plants and bacteria Mucin PF01456.12 KPI43371.1 - 1.3e-07 31.4 14.4 1.3e-07 31.4 10.0 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein Peptidase_MA_2 PF13485.1 KPI43371.1 - 1.4e-06 28.3 0.3 1.4e-05 25.1 0.2 2.2 1 1 0 1 1 1 1 Peptidase MA superfamily Sporozoite_P67 PF05642.6 KPI43371.1 - 0.07 10.9 8.8 0.096 10.5 6.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4512 PF14975.1 KPI43371.1 - 0.65 10.8 5.7 1.6 9.6 4.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) MGC-24 PF05283.6 KPI43371.1 - 5 6.8 15.3 8.2 6.1 10.6 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) TMEM154 PF15102.1 KPI43371.1 - 5.9 6.5 7.7 12 5.5 5.4 1.6 1 0 0 1 1 1 0 TMEM154 protein family OCD_Mu_crystall PF02423.10 KPI43372.1 - 7.8e-12 44.5 0.0 6e-06 25.2 0.0 2.3 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 KPI43372.1 - 1.6e-05 24.9 0.0 0.00018 21.5 0.0 2.2 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KPI43375.1 - 2.3e-23 82.9 0.8 3.2e-23 82.4 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI43375.1 - 1.2e-10 41.6 0.9 1.6e-10 41.2 0.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KPI43375.1 - 3.8e-06 26.2 0.0 1.8e-05 24.0 0.0 1.7 1 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.5 KPI43375.1 - 2.7e-05 23.9 1.6 5.5e-05 22.9 1.1 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI43375.1 - 0.0018 18.3 0.1 0.0027 17.7 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KPI43375.1 - 0.0075 15.2 0.2 0.0092 15.0 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 KPI43375.1 - 0.092 12.5 0.0 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Peptidase_S24 PF00717.18 KPI43376.1 - 3.5e-08 32.9 0.2 1.1e-07 31.3 0.2 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KPI43376.1 - 0.11 12.0 0.1 3.3 7.2 0.0 2.6 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 VWA_3 PF13768.1 KPI43377.1 - 2.7e-30 105.1 0.0 6.6e-30 103.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 KPI43377.1 - 1.8e-21 75.9 0.0 4.9e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 KPI43377.1 - 6.1e-11 42.7 0.0 1.8e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 KPI43377.1 - 6.5e-09 35.1 0.0 1.5e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 KPI43377.1 - 1.1e-05 25.2 0.0 2.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Nucleoporin_FG PF13634.1 KPI43377.1 - 0.0054 16.9 32.7 0.0054 16.9 22.7 2.8 2 1 0 2 2 2 1 Nucleoporin FG repeat region AMP-binding PF00501.23 KPI43378.1 - 4.1e-72 242.8 0.1 5.3e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI43378.1 - 1.5e-13 51.5 0.2 3.7e-13 50.2 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RCC_reductase PF06405.6 KPI43379.1 - 0.013 14.4 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) Asp_Glu_race PF01177.17 KPI43383.1 - 3.8e-11 43.3 0.0 4.8e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase NmrA PF05368.8 KPI43384.1 - 1.2e-07 31.1 0.0 2.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI43384.1 - 0.00095 19.2 0.4 0.0068 16.4 0.3 2.2 1 1 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KPI43384.1 - 0.053 13.5 0.1 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 KPI43384.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.5 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 KPI43385.1 - 7.9e-16 58.0 0.4 1.4e-12 47.3 0.3 3.0 2 1 0 2 2 2 2 FAD binding domain Uds1 PF15456.1 KPI43386.1 - 1e-40 138.5 2.2 1e-40 138.5 1.6 5.1 2 1 2 5 5 5 2 Up-regulated During Septation WEMBL PF05701.6 KPI43386.1 - 3.4 6.0 63.1 0.033 12.6 19.2 4.4 2 2 2 4 4 4 0 Weak chloroplast movement under blue light V_ATPase_I PF01496.14 KPI43386.1 - 9.4 3.9 42.9 6.5 4.4 0.0 3.5 2 1 1 3 3 3 0 V-type ATPase 116kDa subunit family PGAP1 PF07819.8 KPI43387.1 - 1.2e-80 270.3 0.0 1.7e-80 269.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KPI43387.1 - 2.3e-05 24.1 0.0 5.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI43387.1 - 0.00054 19.8 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI43387.1 - 0.00056 19.5 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 KPI43387.1 - 0.0075 15.5 0.1 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 KPI43387.1 - 0.022 13.7 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 KPI43387.1 - 0.098 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) COesterase PF00135.23 KPI43387.1 - 0.21 10.2 0.0 0.32 9.6 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family RNase_T PF00929.19 KPI43388.1 - 9.1e-07 29.3 0.0 1.8e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DUF4129 PF13559.1 KPI43389.1 - 0.0044 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) NICE-3 PF07406.6 KPI43389.1 - 0.04 13.4 0.2 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 NICE-3 protein DUF3904 PF13044.1 KPI43389.1 - 0.19 10.0 0.0 0.27 9.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3904) DUF975 PF06161.6 KPI43389.1 - 0.2 11.3 1.1 0.28 10.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF975) Ribosomal_L16 PF00252.13 KPI43390.1 - 4.3e-29 100.9 0.1 6e-29 100.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Epimerase PF01370.16 KPI43391.1 - 2.1e-10 40.4 0.0 3.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI43391.1 - 2.8e-10 39.3 0.0 4.7e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KPI43391.1 - 1.2e-07 30.9 0.0 7e-06 25.1 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KPI43391.1 - 2.4e-07 30.9 0.6 1.5e-06 28.3 0.4 2.2 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KPI43391.1 - 1.9e-05 24.0 0.2 3.9e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 KPI43391.1 - 0.006 16.5 0.9 0.025 14.5 0.4 2.2 2 1 0 2 2 2 1 short chain dehydrogenase KH_1 PF00013.24 KPI43392.1 - 2e-31 107.4 3.2 1.3e-07 31.1 0.3 7.4 7 0 0 7 7 7 5 KH domain KH_3 PF13014.1 KPI43392.1 - 2e-25 87.9 2.0 0.00022 20.7 0.0 6.1 6 0 0 6 6 6 5 KH domain Limkain-b1 PF11608.3 KPI43392.1 - 0.031 14.0 0.1 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 SUV3_C PF12513.3 KPI43392.1 - 0.083 12.3 0.1 0.23 10.9 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal Pkinase PF00069.20 KPI43394.1 - 4.6e-43 147.2 0.0 6.9e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI43394.1 - 2.5e-15 56.2 0.0 3.4e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KPI43394.1 - 1e-06 28.7 0.7 0.0038 16.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KPI43394.1 - 0.00082 18.4 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KPI43394.1 - 0.0062 15.6 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KPI43394.1 - 0.023 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family zf-CCHC PF00098.18 KPI43395.1 - 1.3e-08 34.3 3.7 1.7e-05 24.5 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 KPI43395.1 - 0.0011 18.5 0.1 0.0022 17.5 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 KPI43395.1 - 0.034 13.8 0.3 0.5 10.1 0.0 2.4 1 1 1 2 2 2 0 Zinc knuckle eIF3g PF12353.3 KPI43395.1 - 0.059 13.2 1.2 1 9.2 0.1 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_4 PF14392.1 KPI43395.1 - 0.33 10.6 2.2 0.44 10.2 0.3 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 KPI43395.1 - 1.6 8.4 5.0 0.45 10.2 0.5 2.3 3 0 0 3 3 3 0 Zinc knuckle Macro PF01661.16 KPI43396.1 - 3.7e-40 136.4 0.4 6e-40 135.8 0.3 1.3 1 0 0 1 1 1 1 Macro domain RAMP PF04901.8 KPI43397.1 - 0.016 14.9 0.2 0.74 9.5 0.1 2.8 3 0 0 3 3 3 0 Receptor activity modifying family Slx4 PF09494.5 KPI43397.1 - 0.37 10.5 2.5 52 3.6 0.1 3.2 3 0 0 3 3 3 0 Slx4 endonuclease F-box-like PF12937.2 KPI43397.1 - 3.3 7.5 9.5 21 4.9 0.1 4.0 2 1 2 4 4 4 0 F-box-like RTA1 PF04479.8 KPI43398.1 - 2.6e-44 151.3 0.6 4.1e-44 150.7 0.1 1.5 1 1 1 2 2 2 1 RTA1 like protein Lung_7-TM_R PF06814.8 KPI43398.1 - 0.11 11.4 0.1 0.11 11.4 0.1 3.2 3 2 1 4 4 4 0 Lung seven transmembrane receptor Ribosomal_L7Ae PF01248.21 KPI43399.1 - 7.8e-20 70.1 3.3 8.6e-19 66.8 0.4 3.1 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KPI43399.1 - 0.0012 18.7 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 RNase P subunit Pop3 AAA PF00004.24 KPI43401.1 - 1.6e-17 63.9 0.0 3.4e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KPI43401.1 - 0.0037 16.9 0.1 0.76 9.5 0.0 2.7 3 0 0 3 3 3 2 Part of AAA domain AAA_22 PF13401.1 KPI43401.1 - 0.0078 16.3 0.0 0.024 14.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.18 KPI43402.1 - 6.9e-67 225.3 0.0 1.3e-66 224.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KPI43402.1 - 1.8e-18 66.1 0.0 4.1e-17 61.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI43402.1 - 2.5e-07 30.6 0.2 1.6e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Use1 PF09753.4 KPI43403.1 - 1.4e-07 31.2 4.3 2.1e-07 30.6 3.0 1.4 1 0 0 1 1 1 1 Membrane fusion protein Use1 HECT PF00632.20 KPI43404.1 - 8.4e-73 245.2 0.0 1.3e-72 244.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ADH_N PF08240.7 KPI43405.1 - 4.2e-28 97.2 2.2 1.2e-27 95.8 1.5 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI43405.1 - 7.5e-19 67.5 0.4 1.4e-18 66.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.16 KPI43405.1 - 0.0021 17.9 0.4 0.077 12.8 0.3 2.3 2 0 0 2 2 2 1 ThiF family ADH_zinc_N_2 PF13602.1 KPI43405.1 - 0.0034 18.2 0.0 0.01 16.7 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 KPI43405.1 - 0.0081 15.1 0.2 0.014 14.3 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 KPI43405.1 - 0.044 14.0 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KPI43405.1 - 0.044 13.1 0.2 0.077 12.3 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 KPI43405.1 - 0.066 13.2 0.5 0.14 12.2 0.3 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MobB PF03205.9 KPI43405.1 - 0.075 12.7 0.7 0.51 10.0 0.1 2.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Semialdhyde_dh PF01118.19 KPI43405.1 - 0.11 12.7 0.1 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KPI43405.1 - 0.16 11.0 0.2 0.26 10.4 0.2 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PQ-loop PF04193.9 KPI43406.1 - 2.4e-20 71.8 4.8 4.9e-20 70.8 0.5 2.5 2 0 0 2 2 2 1 PQ loop repeat Acyl_transf_3 PF01757.17 KPI43406.1 - 0.012 14.4 4.4 0.014 14.2 3.0 1.2 1 0 0 1 1 1 0 Acyltransferase family MFS_1 PF07690.11 KPI43406.1 - 0.015 13.9 1.4 0.018 13.7 0.6 1.3 1 1 0 1 1 1 0 Major Facilitator Superfamily S1FA PF04689.8 KPI43406.1 - 0.067 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 DNA binding protein S1FA Zip PF02535.17 KPI43407.1 - 1.9e-49 168.3 2.2 2.3e-49 168.1 1.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Tetraspannin PF00335.15 KPI43408.1 - 0.024 13.9 3.6 0.037 13.2 2.5 1.4 1 1 0 1 1 1 0 Tetraspanin family DUF221 PF02714.10 KPI43408.1 - 0.049 12.4 1.5 0.056 12.3 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function DUF221 DUF3735 PF12537.3 KPI43408.1 - 0.11 12.6 0.2 0.25 11.3 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3735) UPF0060 PF02694.10 KPI43408.1 - 0.29 11.1 5.6 0.56 10.2 3.9 1.5 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family Bacteriocin_IId PF09221.5 KPI43408.1 - 3.4 7.6 11.9 1.1 9.2 1.3 2.7 3 0 0 3 3 3 0 Bacteriocin class IId cyclical uberolysin-like DUF3262 PF11660.3 KPI43408.1 - 8.4 6.5 10.6 8.9 6.4 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3262) PIG-F PF06699.6 KPI43409.1 - 1.5e-36 126.1 10.8 1.1e-35 123.2 7.5 1.9 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F Aa_trans PF01490.13 KPI43411.1 - 5.7e-80 268.7 25.7 6.6e-80 268.5 17.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Mito_carr PF00153.22 KPI43412.1 - 9.6e-58 191.9 0.4 3.7e-19 68.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SH3_9 PF14604.1 KPI43413.1 - 4.4e-10 38.9 0.0 6.5e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KPI43413.1 - 8.4e-08 31.5 0.0 1.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KPI43413.1 - 3e-07 29.7 0.0 4.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 SH3 domain DUF4366 PF14283.1 KPI43413.1 - 0.017 14.5 0.1 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) IncA PF04156.9 KPI43413.1 - 0.019 14.5 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 IncA protein VSP PF03302.8 KPI43413.1 - 0.021 13.4 1.6 0.027 13.1 1.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Podoplanin PF05808.6 KPI43413.1 - 0.098 12.2 1.9 0.19 11.2 1.3 1.4 1 0 0 1 1 1 0 Podoplanin DUF533 PF04391.7 KPI43413.1 - 0.24 10.7 5.6 3.1 7.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF533) dsrm PF00035.20 KPI43414.1 - 5.6e-07 30.0 0.3 1.4e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 KPI43414.1 - 4.7e-06 26.5 0.0 0.0023 17.8 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KPI43414.1 - 0.0058 17.0 0.0 0.021 15.2 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain Ribul_P_3_epim PF00834.14 KPI43415.1 - 2.5e-51 173.6 0.0 1.3e-49 168.0 0.0 2.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 KPI43415.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.19 KPI43415.1 - 0.021 14.2 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.9 KPI43415.1 - 0.026 13.6 0.3 0.042 12.9 0.2 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG AP_endonuc_2 PF01261.19 KPI43415.1 - 0.081 12.1 0.1 0.79 8.9 0.0 2.2 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel PcrB PF01884.12 KPI43415.1 - 0.12 11.6 0.2 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 PcrB family Phosphodiest PF01663.17 KPI43415.1 - 0.14 11.4 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase zf-BED PF02892.10 KPI43417.1 - 0.055 13.2 0.2 0.53 10.0 0.0 2.3 2 0 0 2 2 2 0 BED zinc finger AvrE PF11725.3 KPI43418.1 - 5.3 3.9 16.8 7.2 3.4 11.6 1.1 1 0 0 1 1 1 0 Pathogenicity factor Macoilin PF09726.4 KPI43418.1 - 9.2 4.4 17.1 13 3.9 11.9 1.3 1 0 0 1 1 1 0 Transmembrane protein AMP-binding PF00501.23 KPI43419.1 - 1.8e-83 280.3 0.0 2.1e-83 280.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI43419.1 - 4e-12 46.8 0.0 1.1e-11 45.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NDT80_PhoG PF05224.7 KPI43420.1 - 3.5e-36 124.9 0.0 6.5e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family RGS PF00615.14 KPI43421.1 - 0.017 15.1 0.0 0.11 12.6 0.0 2.2 1 1 0 1 1 1 0 Regulator of G protein signaling domain 7tm_1 PF00001.16 KPI43423.1 - 0.042 12.9 0.0 0.51 9.4 0.0 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Aldedh PF00171.17 KPI43425.1 - 2.1e-155 517.6 0.0 2.5e-155 517.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SASRP1 PF15160.1 KPI43425.1 - 0.37 9.9 3.4 0.31 10.2 1.2 1.6 2 0 0 2 2 2 0 Spermatogenesis-associated serine-rich protein 1 Cullin PF00888.17 KPI43426.1 - 1e-193 645.1 17.0 1.4e-193 644.6 11.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KPI43426.1 - 9.8e-27 92.5 3.2 9.8e-27 92.5 2.2 2.6 3 0 0 3 3 3 1 Cullin protein neddylation domain WGG PF10273.4 KPI43426.1 - 0.077 13.0 2.3 10 6.2 0.0 3.7 5 0 0 5 5 5 0 Pre-rRNA-processing protein TSR2 WSC PF01822.14 KPI43427.1 - 2.9e-80 264.2 87.2 3.3e-16 58.9 10.2 5.6 5 0 0 5 5 5 5 WSC domain PQQ_3 PF13570.1 KPI43427.1 - 5.3e-05 23.3 7.1 0.054 13.7 0.1 4.2 4 0 0 4 4 4 2 PQQ-like domain PQQ_2 PF13360.1 KPI43427.1 - 0.00014 21.4 0.8 0.39 10.1 0.0 3.7 4 0 0 4 4 4 2 PQQ-like domain DUF386 PF04074.7 KPI43427.1 - 0.17 11.3 0.0 0.84 9.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF386) Transp_cyt_pur PF02133.10 KPI43428.1 - 2e-101 339.7 44.9 2.3e-101 339.5 31.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin bZIP_1 PF00170.16 KPI43429.1 - 0.034 14.0 2.9 0.049 13.6 2.0 1.2 1 0 0 1 1 1 0 bZIP transcription factor PRCC PF10253.4 KPI43429.1 - 0.094 13.4 4.1 0.18 12.4 2.9 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Phage_GP20 PF06810.6 KPI43429.1 - 0.17 11.3 0.7 0.24 10.8 0.5 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DnaJ PF00226.26 KPI43430.1 - 2.1e-25 88.2 1.4 3.5e-25 87.4 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KPI43430.1 - 3e-23 81.5 0.2 6.3e-21 74.0 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KPI43430.1 - 2.1e-13 50.1 18.5 3.8e-13 49.2 12.8 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KPI43430.1 - 0.016 14.8 10.5 0.4 10.3 1.8 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 KPI43430.1 - 2.3 8.5 6.5 3.5 7.9 2.1 2.8 1 1 2 3 3 3 0 Restriction alleviation protein Lar zinc-ribbons_6 PF07191.7 KPI43430.1 - 2.7 7.8 6.5 4.7 7.0 1.0 2.4 2 0 0 2 2 2 0 zinc-ribbons CRM1_C PF08767.6 KPI43431.1 - 4.3e-135 449.7 4.8 4.3e-135 449.7 3.3 2.7 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 KPI43431.1 - 7.4e-40 136.2 9.0 4.8e-39 133.6 5.5 3.1 2 0 0 2 2 2 1 Exportin 1-like protein MIP PF00230.15 KPI43432.1 - 4.5e-43 147.3 5.6 6.1e-43 146.8 3.9 1.2 1 0 0 1 1 1 1 Major intrinsic protein Acetyltransf_8 PF13523.1 KPI43433.1 - 1.3e-46 158.2 0.0 1.9e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KPI43433.1 - 0.00033 20.8 0.0 0.0011 19.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KPI43433.1 - 0.011 15.6 0.0 0.029 14.3 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 KPI43434.1 - 7.4e-27 93.9 11.0 9.4e-27 93.6 7.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily CorA PF01544.13 KPI43435.1 - 3.5e-09 36.1 0.5 8.9e-09 34.7 0.1 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF1736 PF08409.6 KPI43435.1 - 0.082 12.4 0.6 0.19 11.3 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1736) NmrA PF05368.8 KPI43438.1 - 4.2e-20 71.9 0.0 6.1e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI43438.1 - 8.6e-16 58.4 0.2 1.1e-15 58.1 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI43438.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KPI43438.1 - 0.039 13.9 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.10 KPI43438.1 - 0.039 13.7 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 KPI43438.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Mus7 PF09462.5 KPI43441.1 - 2e-26 93.0 6.9 2e-26 93.0 4.8 2.0 2 1 0 2 2 2 1 Mus7/MMS22 family Ribonuclease_3 PF00636.21 KPI43442.1 - 1.2e-35 122.3 0.0 2e-19 70.1 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KPI43442.1 - 4e-25 88.2 3.2 5.7e-13 48.9 0.0 4.0 3 1 1 4 4 4 3 Ribonuclease-III-like DEAD PF00270.24 KPI43442.1 - 5e-16 58.6 0.0 1.2e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI43442.1 - 1.2e-14 53.8 0.2 4.1e-14 52.1 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 KPI43442.1 - 1.3e-14 53.6 0.1 5.9e-14 51.6 0.0 2.3 2 0 0 2 2 2 1 Dicer dimerisation domain ResIII PF04851.10 KPI43442.1 - 1e-12 48.2 0.0 3.2e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RRM_1 PF00076.17 KPI43443.1 - 9.4e-25 86.0 0.0 6.4e-15 54.5 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI43443.1 - 2.3e-20 72.3 0.0 2.6e-12 46.5 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI43443.1 - 3.7e-17 61.9 0.0 3.9e-10 39.4 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_4 PF08386.5 KPI43443.1 - 6.3e-17 61.3 0.0 1.6e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KPI43443.1 - 2.1e-11 43.8 0.0 7.5e-11 42.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI43443.1 - 1e-05 25.5 0.0 6.7e-05 22.8 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1797 PF08796.5 KPI43443.1 - 0.21 11.4 0.0 0.45 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) Pyr_redox_3 PF13738.1 KPI43444.1 - 6.7e-14 52.4 0.0 1.3e-12 48.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI43444.1 - 9.5e-10 38.6 0.0 3.1e-07 30.4 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI43444.1 - 1.2e-09 36.9 0.1 4.3e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI43444.1 - 6.1e-06 26.1 0.0 0.00015 21.7 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 KPI43444.1 - 0.00095 18.3 0.1 0.0022 17.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KPI43444.1 - 0.0018 17.4 0.0 0.0034 16.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.1 KPI43444.1 - 0.0022 16.9 0.3 0.39 9.5 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KPI43444.1 - 0.0027 16.2 0.2 0.078 11.4 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein DUF4440 PF14534.1 KPI43444.1 - 0.0042 17.2 0.0 0.0097 16.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) NAD_binding_9 PF13454.1 KPI43444.1 - 0.013 15.3 0.5 9.4 5.9 0.2 3.1 2 1 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KPI43444.1 - 0.032 13.0 0.3 0.052 12.3 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain SnoaL_3 PF13474.1 KPI43444.1 - 0.034 14.1 0.1 0.089 12.8 0.1 1.7 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.2 KPI43444.1 - 0.074 13.4 0.1 0.29 11.5 0.0 2.1 2 0 0 2 2 2 0 SnoaL-like domain TrkA_N PF02254.13 KPI43444.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 KPI43444.1 - 0.12 11.4 0.0 0.98 8.4 0.0 2.2 2 0 0 2 2 2 0 Thi4 family RhoGAP PF00620.22 KPI43447.1 - 6.4e-48 162.2 0.2 2.2e-47 160.4 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 KPI43447.1 - 1.2e-14 54.1 17.3 2.7e-09 36.9 1.2 2.4 2 0 0 2 2 2 2 LIM domain CmcI PF04989.7 KPI43447.1 - 0.089 12.0 0.6 0.45 9.7 0.5 2.1 2 0 0 2 2 2 0 Cephalosporin hydroxylase zinc_ribbon_2 PF13240.1 KPI43447.1 - 0.24 10.9 9.2 0.41 10.1 0.0 4.0 4 1 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KPI43447.1 - 1.9 8.4 19.1 0.29 11.1 1.0 4.1 3 1 0 3 3 3 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 KPI43447.1 - 3.1 7.2 16.4 5.7 6.3 0.0 4.8 4 1 0 4 4 4 0 TFIIB zinc-binding PH_11 PF15413.1 KPI43447.1 - 4 7.7 5.4 0.57 10.4 0.1 2.3 3 0 0 3 3 3 0 Pleckstrin homology domain Aldedh PF00171.17 KPI43448.1 - 1.1e-98 330.5 10.1 3e-56 190.7 0.7 2.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF4267 PF14087.1 KPI43449.1 - 0.012 15.1 0.1 0.02 14.4 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4267) Transp_cyt_pur PF02133.10 KPI43450.1 - 4.2e-35 121.1 32.8 3.6e-34 118.0 22.7 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF791 PF05631.9 KPI43451.1 - 1.7e-61 207.8 9.6 2.5e-61 207.3 6.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 KPI43451.1 - 1.4e-15 56.8 30.7 1.4e-15 56.8 21.3 1.9 3 0 0 3 3 3 1 Major Facilitator Superfamily Glyco_hydro_32N PF00251.15 KPI43453.1 - 2.7e-26 92.6 7.5 3.3e-26 92.3 5.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain zf-UBR PF02207.15 KPI43454.1 - 3.7e-16 58.6 4.1 3.7e-16 58.6 2.9 3.4 4 0 0 4 4 4 2 Putative zinc finger in N-recognin (UBR box) Pyr_redox_3 PF13738.1 KPI43455.1 - 1.8e-18 67.3 0.0 3.1e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI43455.1 - 1.1e-06 27.1 0.0 8.3e-06 24.2 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KPI43455.1 - 2.9e-06 26.4 0.0 9.9e-05 21.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 KPI43455.1 - 9.7e-05 22.4 0.3 0.015 15.4 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 KPI43455.1 - 0.0025 17.7 0.0 0.13 12.0 0.0 2.7 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI43455.1 - 0.05 13.6 0.1 0.19 11.7 0.1 2.1 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI43455.1 - 0.085 11.6 0.2 0.15 10.8 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 KPI43455.1 - 0.09 11.6 0.0 0.98 8.2 0.0 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.19 KPI43455.1 - 0.19 10.5 0.8 12 4.6 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Mt_ATP-synt_B PF05405.9 KPI43456.1 - 4.8e-49 165.9 1.8 6.1e-49 165.6 1.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) BON PF04972.12 KPI43456.1 - 0.014 15.1 1.4 9.9 6.0 0.1 3.7 2 1 1 3 3 3 0 BON domain Band_7 PF01145.20 KPI43457.1 - 3.4e-24 85.7 4.0 5.7e-24 84.9 2.7 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Steroid_dh PF02544.11 KPI43458.1 - 1.1e-32 112.8 0.1 1.7e-32 112.2 0.1 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KPI43458.1 - 6.6e-06 25.5 0.8 8.8e-06 25.1 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KPI43458.1 - 0.00015 21.8 0.1 0.00032 20.7 0.1 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase ADH_zinc_N PF00107.21 KPI43460.1 - 3.4e-11 42.7 0.0 9.1e-10 38.1 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI43460.1 - 5.8e-07 29.2 0.3 8.8e-06 25.4 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Phosphodiest PF01663.17 KPI43461.1 - 1.3e-85 287.9 0.4 2e-85 287.3 0.3 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase CDC27 PF09507.5 KPI43461.1 - 0.13 11.4 5.1 0.23 10.6 3.5 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Arf PF00025.16 KPI43462.1 - 1.4e-74 249.1 0.1 1.6e-74 248.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KPI43462.1 - 6.7e-12 45.0 0.0 7.1e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KPI43462.1 - 2.3e-11 43.2 0.0 2.8e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KPI43462.1 - 7.3e-11 41.3 2.0 1.9e-07 30.0 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KPI43462.1 - 1.6e-10 40.5 0.0 2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KPI43462.1 - 1.8e-06 28.4 0.0 2.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KPI43462.1 - 0.00017 21.5 0.1 0.00035 20.5 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KPI43462.1 - 0.019 14.0 0.1 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PTPA PF03095.10 KPI43463.1 - 7.7e-110 366.7 0.0 9e-110 366.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein F-box-like PF12937.2 KPI43464.1 - 0.00068 19.3 0.0 0.005 16.5 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KPI43464.1 - 0.026 14.1 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 F-box domain SSF PF00474.12 KPI43465.1 - 5e-21 74.8 29.1 7.4e-21 74.2 20.1 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family FPN1 PF06963.7 KPI43466.1 - 6.7e-110 367.4 18.8 7.7e-110 367.2 13.0 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Methyltransf_24 PF13578.1 KPI43467.1 - 4.6e-07 30.6 0.1 2.2e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI43467.1 - 0.00019 21.9 0.0 0.00038 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI43467.1 - 0.051 14.0 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_3 PF00933.16 KPI43468.1 - 3.7e-60 203.4 0.0 5.3e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 KPI43468.1 - 2.8e-07 30.4 0.0 2e-06 27.7 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_6 PF13480.1 KPI43468.1 - 0.00024 21.0 0.0 0.017 15.0 0.0 3.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KPI43468.1 - 0.071 13.2 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2014 PF09427.5 KPI43469.1 - 4.3e-71 239.1 0.2 6.7e-71 238.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 KPI43469.1 - 4.4e-19 67.9 0.5 8.6e-19 66.9 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.16 KPI43469.1 - 0.0018 18.1 2.4 0.0031 17.4 0.1 2.1 2 0 0 2 2 2 1 bZIP transcription factor DUF904 PF06005.7 KPI43469.1 - 0.21 11.8 0.8 0.6 10.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Pentapeptide PF00805.17 KPI43470.1 - 0.0077 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 KPI43470.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) CybS PF05328.7 KPI43470.1 - 0.16 11.5 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 CybS DUF3610 PF12272.3 KPI43470.1 - 0.17 11.5 3.0 0.38 10.3 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3610) PIN_3 PF13470.1 KPI43470.1 - 0.2 12.3 0.7 0.62 10.7 0.0 2.1 2 0 0 2 2 2 0 PIN domain TPR_11 PF13414.1 KPI43471.1 - 1.5e-06 27.7 0.8 0.034 13.7 0.4 2.4 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 KPI43471.1 - 2.5e-05 24.1 0.1 0.11 12.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KPI43471.1 - 0.00022 20.9 2.0 0.015 15.1 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KPI43471.1 - 0.00047 20.5 7.5 0.0086 16.6 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KPI43471.1 - 0.0015 19.1 3.5 0.052 14.2 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KPI43471.1 - 0.0028 17.4 0.4 3.2 7.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KPI43471.1 - 0.0031 17.8 3.7 0.01 16.2 0.0 3.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KPI43471.1 - 0.0035 16.9 0.0 0.021 14.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KPI43471.1 - 0.005 17.1 0.1 0.17 12.2 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KPI43471.1 - 0.11 12.4 2.8 1.1 9.2 0.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KPI43471.1 - 0.28 11.7 0.0 0.28 11.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MCM PF00493.18 KPI43472.1 - 3.6e-63 213.3 0.0 4.4e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 KPI43472.1 - 0.049 12.7 0.1 0.15 11.2 0.1 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_32 PF13654.1 KPI43472.1 - 0.079 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain UEV PF05743.8 KPI43473.1 - 7.4e-30 103.1 0.0 1.6e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 KPI43473.1 - 3.7e-14 52.0 0.4 3.1e-13 49.1 0.0 2.3 2 1 0 2 2 2 1 Vps23 core domain IncA PF04156.9 KPI43473.1 - 0.00024 20.7 5.5 0.00024 20.7 3.2 1.4 1 1 0 1 1 1 1 IncA protein TMF_TATA_bd PF12325.3 KPI43473.1 - 0.0042 16.7 1.3 0.0067 16.1 0.9 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding NTR2 PF15458.1 KPI43473.1 - 0.0063 15.7 0.7 0.013 14.7 0.5 1.6 1 0 0 1 1 1 1 Nineteen complex-related protein 2 TBPIP PF07106.8 KPI43473.1 - 0.053 13.0 1.3 0.084 12.4 0.9 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Reo_sigmaC PF04582.7 KPI43473.1 - 0.072 12.2 7.6 0.1 11.7 5.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF972 PF06156.8 KPI43473.1 - 0.11 12.8 0.4 0.19 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Filament PF00038.16 KPI43473.1 - 0.13 11.6 2.7 0.2 11.1 1.9 1.1 1 0 0 1 1 1 0 Intermediate filament protein Baculo_PEP_C PF04513.7 KPI43473.1 - 0.14 11.9 7.9 0.22 11.3 5.5 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Myosin_tail_1 PF01576.14 KPI43473.1 - 0.21 9.2 3.2 0.28 8.8 2.2 1.0 1 0 0 1 1 1 0 Myosin tail Prominin PF05478.6 KPI43473.1 - 0.47 7.9 2.5 0.65 7.4 1.8 1.0 1 0 0 1 1 1 0 Prominin DivIC PF04977.10 KPI43473.1 - 1.1 8.7 3.4 4.6 6.7 1.3 2.1 1 1 1 2 2 2 0 Septum formation initiator ADIP PF11559.3 KPI43473.1 - 1.2 9.0 7.4 1.9 8.3 5.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF148 PF02520.12 KPI43473.1 - 3 7.6 6.7 4.1 7.2 3.9 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF148 Corona_S2 PF01601.11 KPI43473.1 - 6.6 4.7 5.3 9.1 4.2 3.7 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein HSP70 PF00012.15 KPI43474.1 - 0.075 10.9 0.0 0.55 8.0 0.0 1.9 2 0 0 2 2 2 0 Hsp70 protein DUF4482 PF14818.1 KPI43477.1 - 0.028 15.0 1.7 0.053 14.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) XkdW PF09636.5 KPI43477.1 - 0.048 13.5 0.5 0.52 10.2 0.1 2.4 2 0 0 2 2 2 0 XkdW protein Nop25 PF09805.4 KPI43478.1 - 0.0014 18.7 2.5 0.0014 18.7 1.7 2.4 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) MMtag PF10159.4 KPI43478.1 - 0.23 11.5 8.4 0.6 10.1 5.5 2.0 1 1 0 1 1 1 0 Kinase phosphorylation protein AMP-binding PF00501.23 KPI43479.1 - 9.2e-31 106.6 0.0 1.8e-29 102.3 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme PA26 PF04636.8 KPI43479.1 - 0.045 12.4 0.0 0.072 11.7 0.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Peptidase_M20 PF01546.23 KPI43480.1 - 9.1e-22 77.4 0.8 1.2e-21 77.0 0.6 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KPI43480.1 - 4.3e-07 29.6 0.0 9.6e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KPI43480.1 - 0.00034 20.4 0.1 0.00083 19.1 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M28 DUF2236 PF09995.4 KPI43482.1 - 2.5e-35 121.9 0.2 3.6e-35 121.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) zf-MYND PF01753.13 KPI43483.1 - 0.021 14.6 2.2 0.021 14.6 1.5 2.2 2 0 0 2 2 2 0 MYND finger SET PF00856.23 KPI43483.1 - 0.053 13.8 0.0 3.5 7.9 0.0 2.5 2 0 0 2 2 2 0 SET domain AAA_22 PF13401.1 KPI43484.1 - 2.6e-07 30.8 0.0 9.7e-05 22.5 0.0 3.1 1 1 1 2 2 2 1 AAA domain TPR_14 PF13428.1 KPI43484.1 - 2e-06 27.9 2.6 1 10.1 0.0 5.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KPI43484.1 - 3e-06 27.0 2.2 0.23 11.4 0.0 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KPI43484.1 - 1.1e-05 24.9 6.1 0.86 9.2 0.1 4.3 3 1 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 KPI43484.1 - 8.2e-05 22.0 1.0 0.43 10.2 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KPI43484.1 - 0.00028 20.4 2.5 0.031 14.0 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KPI43484.1 - 0.00049 20.7 3.2 1.1 9.9 0.1 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KPI43484.1 - 0.026 14.4 7.4 10 6.3 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KPI43484.1 - 0.87 9.6 5.7 19 5.3 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 KPI43484.1 - 3.2 8.4 6.6 12 6.6 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat F-box PF00646.28 KPI43485.1 - 0.0011 18.5 0.1 0.0023 17.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain HhH-GPD PF00730.20 KPI43486.1 - 1.1e-05 25.6 0.0 1.6e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KPI43486.1 - 0.04 13.6 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif C1_4 PF07975.7 KPI43487.1 - 0.058 13.3 3.2 0.13 12.2 2.2 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain Whi5 PF08528.6 KPI43488.1 - 1.3e-06 27.8 0.1 2.9e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 Whi5 like NTF2 PF02136.15 KPI43490.1 - 1.4e-23 83.4 0.1 2.5e-23 82.6 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 KPI43490.1 - 1.1e-08 34.5 0.0 1.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI43490.1 - 3.3e-05 23.7 0.0 5.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI43490.1 - 0.0045 16.8 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KPI43490.1 - 0.011 15.5 0.0 0.031 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA binding motif PAT1 PF09770.4 KPI43490.1 - 4.1 5.5 16.2 6.9 4.7 11.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SET PF00856.23 KPI43492.1 - 1.5e-09 38.3 0.0 2.8e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 SET domain Inhibitor_I9 PF05922.11 KPI43492.1 - 0.022 15.3 0.1 0.057 13.9 0.0 1.7 2 0 0 2 2 2 0 Peptidase inhibitor I9 EHN PF06441.7 KPI43493.1 - 2.3e-38 130.5 0.3 1.4e-37 128.0 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KPI43493.1 - 1.1e-05 25.4 0.9 4.3e-05 23.4 0.2 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI43493.1 - 8.2e-05 22.2 0.0 0.00039 20.0 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Avl9 PF09794.4 KPI43494.1 - 7.7e-110 366.9 0.0 4.7e-108 361.0 0.0 2.1 1 1 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 KPI43494.1 - 5.8e-08 32.4 0.1 0.0059 16.3 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 KPI43494.1 - 0.00026 20.3 0.1 0.01 15.1 0.1 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.16 KPI43494.1 - 0.033 13.9 0.8 0.098 12.3 0.4 1.8 2 0 0 2 2 2 0 DENN (AEX-3) domain Bac_luciferase PF00296.15 KPI43495.1 - 0.091 11.8 0.1 0.1 11.6 0.1 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase FR47 PF08445.5 KPI43496.1 - 3.4e-09 36.3 0.0 1.5e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_3 PF13302.1 KPI43496.1 - 1.1e-05 25.6 0.0 0.00012 22.2 0.0 2.5 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KPI43496.1 - 0.00094 19.1 0.0 0.013 15.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KPI43496.1 - 0.057 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2370 PF10176.4 KPI43497.1 - 0.11 11.8 0.3 0.22 10.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) SNARE_assoc PF09335.6 KPI43498.1 - 4.2e-15 56.0 8.3 6.7e-15 55.3 2.1 2.7 2 1 1 3 3 3 1 SNARE associated Golgi protein DSPn PF14671.1 KPI43499.1 - 3.9e-43 146.8 0.0 1.9e-39 134.8 0.0 3.2 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KPI43499.1 - 1.4e-17 63.4 0.1 4.4e-17 61.9 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KPI43499.1 - 8e-06 25.3 0.0 1.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KPI43499.1 - 0.0081 16.2 0.0 0.027 14.5 0.0 1.9 1 0 0 1 1 1 1 Inositol hexakisphosphate PAN_4 PF14295.1 KPI43501.1 - 7.7e-28 95.9 27.1 1.6e-08 34.0 1.2 4.5 4 0 0 4 4 4 4 PAN domain PAN_1 PF00024.21 KPI43501.1 - 3.9e-15 55.3 9.8 0.0014 18.3 0.0 4.3 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.7 KPI43501.1 - 1.1e-13 50.6 23.0 0.00057 19.4 0.7 4.4 4 0 0 4 4 4 4 PAN-like domain PAN_2 PF08276.6 KPI43501.1 - 0.0023 17.7 20.1 1.4 8.7 0.6 4.4 4 0 0 4 4 4 4 PAN-like domain DUF3292 PF11696.3 KPI43501.1 - 0.08 10.8 0.0 0.11 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) HSP70 PF00012.15 KPI43502.1 - 4.8e-163 543.2 5.3 4.8e-163 543.2 3.7 2.5 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KPI43502.1 - 1.8e-10 39.9 0.0 1.3e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KPI43502.1 - 5.2e-06 26.3 0.7 0.14 11.9 0.2 3.4 2 2 0 2 2 2 2 Cell division protein FtsA NPR3 PF03666.8 KPI43502.1 - 0.0053 15.3 3.1 0.011 14.3 2.1 1.4 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Ketoacyl-synt_C PF02801.17 KPI43502.1 - 0.065 13.0 0.3 0.33 10.8 0.0 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain GTP_EFTU PF00009.22 KPI43503.1 - 2.3e-62 209.7 0.2 3.2e-62 209.3 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KPI43503.1 - 4.9e-36 122.9 0.0 1.6e-35 121.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KPI43503.1 - 4.1e-18 65.0 0.0 9.5e-18 63.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KPI43503.1 - 2.6e-12 46.4 0.0 5.7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KPI43503.1 - 6.9e-12 45.3 1.4 5.3e-11 42.4 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KPI43503.1 - 1.1e-05 25.4 0.1 2.4e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PLA2_B PF01735.13 KPI43504.1 - 3.7e-26 91.3 0.0 1.4e-25 89.4 0.0 1.7 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Ribosomal_60s PF00428.14 KPI43504.1 - 1.8 8.9 14.5 0.76 10.2 7.1 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Aminotran_1_2 PF00155.16 KPI43507.1 - 2e-83 280.3 0.0 5.3e-83 278.9 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II FTA4 PF13093.1 KPI43507.1 - 0.075 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 SEA PF01390.15 KPI43508.1 - 0.085 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 SEA domain Fungal_trans_2 PF11951.3 KPI43509.1 - 0.0005 18.7 0.8 0.00077 18.1 0.5 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain tRNA-synt_1 PF00133.17 KPI43510.1 - 1.9e-34 118.6 0.0 1.9e-25 88.9 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KPI43510.1 - 5.3e-18 64.8 0.0 1.8e-10 40.0 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KPI43510.1 - 7.1e-10 38.8 1.8 1.2e-09 38.1 0.7 1.8 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KPI43510.1 - 1e-05 24.8 0.0 2.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Herpes_UL49_5 PF05702.6 KPI43510.1 - 0.073 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein p450 PF00067.17 KPI43511.1 - 4e-44 150.9 0.0 5.6e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 EPL1 PF10513.4 KPI43512.1 - 1.4e-19 70.9 0.0 6.9e-19 68.6 0.0 2.3 1 1 0 1 1 1 1 Enhancer of polycomb-like PHD_2 PF13831.1 KPI43512.1 - 2.8e-14 52.1 2.1 5.2e-14 51.2 1.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD PF00628.24 KPI43512.1 - 1.9e-09 37.0 5.9 3.7e-09 36.1 4.1 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.1 KPI43512.1 - 0.0021 18.0 0.8 0.06 13.3 0.0 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-PHD-like PF15446.1 KPI43512.1 - 0.0055 16.0 1.1 0.014 14.6 0.8 1.7 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 KPI43512.1 - 0.023 14.3 0.2 0.023 14.3 0.1 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 KPI43512.1 - 0.072 12.9 0.6 0.23 11.3 0.4 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_1 PF14446.1 KPI43512.1 - 0.29 10.8 3.4 0.68 9.7 2.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHF5 PF03660.9 KPI43512.1 - 6.6 6.8 7.2 17 5.5 5.0 1.6 1 1 0 1 1 1 0 PHF5-like protein DUF3176 PF11374.3 KPI43513.1 - 9.3e-27 93.1 1.2 9.3e-27 93.1 0.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF4134 PF13572.1 KPI43513.1 - 0.0013 18.7 0.0 0.0052 16.8 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4134) DctQ PF04290.7 KPI43513.1 - 2.3 7.9 12.3 0.87 9.3 0.1 3.3 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component URO-D PF01208.12 KPI43515.1 - 5e-93 311.7 0.0 6e-93 311.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) LRR_1 PF00560.28 KPI43516.1 - 6.4e-05 22.4 5.6 21 5.6 0.0 6.5 6 2 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.2 KPI43516.1 - 0.00023 20.7 7.1 1.3 8.7 0.1 5.1 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KPI43516.1 - 0.0013 18.5 4.1 55 4.2 0.0 6.6 7 0 0 7 7 7 0 Leucine Rich repeat LRR_7 PF13504.1 KPI43516.1 - 0.28 11.5 8.4 1.1e+02 3.7 0.0 6.4 7 0 0 7 7 7 0 Leucine rich repeat Acyltransferase PF01553.16 KPI43517.1 - 2.8e-12 46.2 0.0 4.9e-11 42.1 0.0 2.4 1 1 0 1 1 1 1 Acyltransferase Pkinase PF00069.20 KPI43518.1 - 6.2e-58 195.9 0.0 9e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI43518.1 - 4.5e-31 107.8 0.0 1.2e-29 103.2 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KPI43518.1 - 0.09 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase BRCT PF00533.21 KPI43519.1 - 1.1e-12 47.9 0.0 2.9e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KPI43519.1 - 1e-09 38.7 0.0 2.2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KPI43519.1 - 2.4e-07 29.8 0.0 3.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 KPI43519.1 - 0.00074 18.6 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KPI43519.1 - 0.001 19.2 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KPI43519.1 - 0.0013 19.5 0.0 0.0013 19.5 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KPI43519.1 - 0.0014 18.5 0.0 0.0034 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KPI43519.1 - 0.0041 17.1 0.0 0.023 14.7 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KPI43519.1 - 0.0055 16.4 0.1 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KPI43519.1 - 0.026 14.4 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KPI43519.1 - 0.051 13.8 0.1 0.051 13.8 0.1 2.4 3 0 0 3 3 2 0 AAA domain PTCB-BRCT PF12738.2 KPI43519.1 - 0.1 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain NACHT PF05729.7 KPI43519.1 - 0.13 11.8 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 NACHT domain UCR_hinge PF02320.11 KPI43521.1 - 3.1e-11 43.0 4.8 6.7e-11 41.9 3.3 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF3399 PF11879.3 KPI43521.1 - 0.024 14.8 7.3 0.05 13.8 5.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) Daxx PF03344.10 KPI43521.1 - 0.45 8.9 33.0 0.67 8.3 22.9 1.2 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 KPI43521.1 - 1.4 7.9 29.7 1.7 7.5 20.6 1.1 1 0 0 1 1 1 0 BUD22 DUF1754 PF08555.5 KPI43522.1 - 6.2e-10 39.5 20.8 5.4e-09 36.5 14.4 2.1 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Ndc1_Nup PF09531.5 KPI43522.1 - 6.6 5.0 6.6 7.5 4.8 4.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Na_sulph_symp PF00939.14 KPI43523.1 - 5.9e-24 84.7 33.2 1e-23 84.0 23.0 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.14 KPI43523.1 - 4.2e-17 62.8 1.0 6.3e-17 62.2 0.7 1.2 1 0 0 1 1 1 1 SPX domain CitMHS PF03600.11 KPI43523.1 - 1.9e-14 53.0 23.8 1.9e-14 53.0 16.5 2.0 1 1 0 1 1 1 1 Citrate transporter Asp-B-Hydro_N PF05279.6 KPI43524.1 - 3.5 7.4 9.3 4.2 7.1 6.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF966 PF06136.8 KPI43524.1 - 8 5.7 18.9 9.6 5.5 13.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) LCD1 PF09798.4 KPI43524.1 - 8.6 4.2 6.6 11 3.9 4.6 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Sugar_tr PF00083.19 KPI43525.1 - 4.7e-20 71.5 15.5 2.3e-19 69.3 9.8 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI43525.1 - 2.5e-14 52.7 28.2 8.8e-12 44.3 5.1 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily HECT PF00632.20 KPI43526.1 - 5.1e-77 259.1 0.0 7.6e-77 258.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Brevenin PF03032.10 KPI43526.1 - 0.18 11.6 1.3 0.4 10.5 0.9 1.5 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family GFA PF04828.9 KPI43528.1 - 2e-09 37.2 0.7 0.00013 21.7 0.0 2.5 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 KPI43528.1 - 0.15 11.7 0.1 0.15 11.7 0.0 2.4 3 0 0 3 3 3 0 Nudix N-terminal zf-NADH-PPase PF09297.6 KPI43528.1 - 1.1 8.8 9.2 0.19 11.2 0.8 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain HD PF01966.17 KPI43529.1 - 7.6e-09 35.6 0.1 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 HD domain DUF706 PF05153.10 KPI43529.1 - 0.0081 15.5 0.0 0.0095 15.2 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD_4 PF13328.1 KPI43529.1 - 0.0081 15.8 0.1 0.017 14.8 0.1 1.6 1 1 0 1 1 1 1 HD domain HDOD PF08668.7 KPI43529.1 - 0.021 14.1 0.0 0.064 12.5 0.0 1.8 1 1 0 1 1 1 0 HDOD domain DASH_Dad2 PF08654.5 KPI43530.1 - 7.2e-31 106.2 0.2 9.2e-31 105.8 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.17 KPI43530.1 - 0.014 15.4 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain EpuA PF11772.3 KPI43532.1 - 0.2 11.1 3.6 0.29 10.6 2.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta GMC_oxred_N PF00732.14 KPI43533.1 - 1.2e-46 159.1 0.0 2e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI43533.1 - 2.7e-32 112.0 0.0 7e-32 110.7 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 KPI43533.1 - 0.042 12.7 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 KPI43533.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF1771 PF08590.5 KPI43534.1 - 1.1e-23 83.0 6.5 2.3e-23 81.9 4.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 KPI43534.1 - 6.7e-16 58.2 0.3 1.8e-15 56.8 0.2 1.8 1 0 0 1 1 1 1 Smr domain Peptidase_M14 PF00246.19 KPI43535.1 - 1.2e-17 64.4 0.1 1.8e-17 63.8 0.1 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 KPI43535.1 - 0.00074 18.4 0.3 0.0032 16.3 0.0 2.0 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.3 KPI43535.1 - 0.0026 16.9 0.0 0.0046 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) DUF3168 PF11367.3 KPI43535.1 - 0.064 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) AAA PF00004.24 KPI43536.1 - 4.5e-15 56.0 0.0 5e-07 29.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KPI43536.1 - 0.00034 19.7 0.0 0.00072 18.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KPI43536.1 - 0.00083 20.1 1.3 0.0037 18.0 0.8 2.3 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 KPI43536.1 - 0.0015 18.6 0.2 0.026 14.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KPI43536.1 - 0.0036 17.0 0.1 0.021 14.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KPI43536.1 - 0.0041 17.1 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 KPI43536.1 - 0.0042 17.0 1.7 0.062 13.2 0.3 3.1 3 1 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 KPI43536.1 - 0.0066 16.5 0.0 0.024 14.7 0.0 1.9 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 KPI43536.1 - 0.019 15.1 0.1 0.099 12.8 0.0 2.3 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 KPI43536.1 - 0.053 13.8 4.0 3.2 8.0 0.9 4.3 4 2 0 4 4 4 0 ABC transporter AAA_25 PF13481.1 KPI43536.1 - 0.068 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain BCS1_N PF08740.6 KPI43536.1 - 0.25 10.9 5.2 0.41 10.2 0.0 3.0 3 0 0 3 3 3 0 BCS1 N terminal CDC45 PF02724.9 KPI43536.1 - 8.7 4.2 17.1 7.9 4.3 0.5 2.3 2 0 0 2 2 2 0 CDC45-like protein Tubulin PF00091.20 KPI43537.1 - 4.2e-74 249.0 0.0 5e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.4 KPI43537.1 - 4.9e-08 33.0 0.0 9.8e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.1 KPI43537.1 - 0.022 13.7 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.1 KPI43537.1 - 0.044 13.2 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain Ribosomal_L1 PF00687.16 KPI43538.1 - 3.8e-57 193.1 2.5 5.3e-57 192.6 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Pkinase PF00069.20 KPI43539.1 - 5.7e-18 64.9 0.0 1.2e-14 54.1 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KPI43539.1 - 0.00048 19.2 0.0 0.02 13.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase MC1 PF05854.6 KPI43540.1 - 0.0079 16.1 0.5 0.012 15.5 0.3 1.3 1 0 0 1 1 1 1 Non-histone chromosomal protein MC1 PAPA-1 PF04795.7 KPI43541.1 - 7.6e-17 61.8 2.2 3.3e-16 59.7 1.5 2.1 1 0 0 1 1 1 1 PAPA-1-like conserved region Dpy-30 PF05186.8 KPI43543.1 - 7.2e-05 22.1 0.0 0.00029 20.2 0.0 1.9 1 1 0 1 1 1 1 Dpy-30 motif Topo_Zn_Ribbon PF08272.6 KPI43544.1 - 0.16 11.3 0.5 5.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like DUF334 PF03904.8 KPI43544.1 - 0.71 9.1 4.7 0.11 11.8 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF334) CAP_N PF01213.14 KPI43545.1 - 8.2e-70 235.5 17.4 7.7e-69 232.3 12.1 2.3 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KPI43545.1 - 1.8e-42 144.4 1.7 1.9e-41 141.0 1.2 2.1 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Ribosomal_60s PF00428.14 KPI43545.1 - 0.015 15.6 1.6 0.95 9.9 0.5 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein TBCC PF07986.7 KPI43545.1 - 0.038 13.3 1.9 0.12 11.7 0.7 2.0 2 0 0 2 2 2 0 Tubulin binding cofactor C DUF917 PF06032.7 KPI43546.1 - 1.6e-115 385.4 0.1 3.3e-115 384.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 KPI43546.1 - 4.8e-45 153.8 9.4 2.5e-44 151.5 1.9 2.8 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KPI43546.1 - 1.2e-30 106.2 0.5 2.8e-27 95.3 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 KPI43546.1 - 1.6e-06 26.7 2.2 0.013 13.8 0.1 2.6 3 0 0 3 3 3 2 MutL protein BcrAD_BadFG PF01869.15 KPI43546.1 - 0.00054 19.3 0.1 0.00054 19.3 0.1 3.1 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 KPI43546.1 - 0.00081 18.4 0.4 0.66 8.8 0.0 2.8 3 0 0 3 3 3 2 StbA protein FtsA PF14450.1 KPI43546.1 - 0.051 13.4 0.4 12 5.8 0.1 3.5 4 0 0 4 4 4 0 Cell division protein FtsA DLH PF01738.13 KPI43547.1 - 6.7e-21 74.5 0.0 7.6e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KPI43547.1 - 0.0012 18.5 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DAO PF01266.19 KPI43548.1 - 9.2e-46 156.3 0.0 1.5e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI43548.1 - 7.6e-09 34.9 1.1 0.00014 20.8 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 KPI43548.1 - 8.7e-07 28.3 0.3 2e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI43548.1 - 5.1e-05 23.2 0.0 0.00043 20.2 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI43548.1 - 6e-05 22.1 0.2 0.073 11.9 0.1 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 KPI43548.1 - 0.00095 19.1 0.3 0.0047 16.9 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KPI43548.1 - 0.0019 17.1 0.0 0.019 13.8 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 KPI43548.1 - 0.0058 16.2 0.1 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KPI43548.1 - 0.016 13.7 0.3 0.024 13.1 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 KPI43548.1 - 0.022 15.1 0.1 0.052 13.9 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI43548.1 - 0.15 11.0 0.2 0.4 9.7 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Adeno_E3_CR2 PF02439.10 KPI43549.1 - 0.00061 19.2 1.2 0.0012 18.2 0.9 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DAP10 PF07213.6 KPI43549.1 - 0.001 18.7 0.1 0.0025 17.5 0.0 1.6 1 0 0 1 1 1 1 DAP10 membrane protein CFEM PF05730.6 KPI43549.1 - 0.0029 17.4 5.4 0.0051 16.6 3.7 1.4 1 0 0 1 1 1 1 CFEM domain EphA2_TM PF14575.1 KPI43549.1 - 0.013 15.8 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.7 KPI43549.1 - 0.017 14.5 0.1 0.035 13.5 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM154 PF15102.1 KPI43549.1 - 0.16 11.6 0.7 0.41 10.3 0.5 1.8 1 1 0 1 1 1 0 TMEM154 protein family SKG6 PF08693.5 KPI43549.1 - 5.9 6.3 7.4 0.77 9.1 1.9 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Neugrin PF06413.6 KPI43550.1 - 3.2e-07 30.4 0.0 3.2e-07 30.4 0.0 2.8 2 1 1 3 3 3 1 Neugrin MRP-L20 PF12824.2 KPI43550.1 - 0.00016 21.6 8.3 0.00016 21.6 5.7 2.5 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 IDO PF01231.13 KPI43551.1 - 2.8e-127 424.6 0.0 1.8e-88 296.8 0.0 3.0 1 1 2 3 3 3 3 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 KPI43551.1 - 0.2 10.1 0.0 0.29 9.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) ABC_tran PF00005.22 KPI43552.1 - 3.6e-46 156.8 0.7 4.1e-22 78.9 0.0 3.0 4 0 0 4 4 2 2 ABC transporter ABC_tran_2 PF12848.2 KPI43552.1 - 7.3e-21 73.8 3.0 7.3e-21 73.8 2.1 2.8 4 0 0 4 4 1 1 ABC transporter AAA_21 PF13304.1 KPI43552.1 - 6.6e-19 68.9 0.8 0.0022 17.9 0.0 4.3 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 KPI43552.1 - 9.9e-10 38.0 0.2 0.65 9.1 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KPI43552.1 - 2.8e-09 36.3 0.6 0.00082 18.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KPI43552.1 - 2.3e-06 26.8 0.0 0.0073 15.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 KPI43552.1 - 5.7e-06 26.6 1.1 0.047 14.0 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_17 PF13207.1 KPI43552.1 - 5.8e-06 27.1 0.5 0.19 12.5 0.0 3.5 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 KPI43552.1 - 6.5e-06 26.6 9.3 0.045 14.0 0.1 3.6 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.1 KPI43552.1 - 1.8e-05 24.8 0.3 0.13 12.2 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KPI43552.1 - 2.8e-05 24.2 0.0 0.22 11.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KPI43552.1 - 6.3e-05 22.9 0.0 0.13 12.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 KPI43552.1 - 0.0001 21.4 1.1 0.049 12.6 0.0 3.3 3 1 1 4 4 4 1 AAA ATPase domain Miro PF08477.8 KPI43552.1 - 0.00015 22.2 0.0 0.34 11.4 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 KPI43552.1 - 0.00016 21.8 0.3 1.4 9.1 0.0 3.8 3 1 1 4 4 4 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KPI43552.1 - 0.00037 20.1 1.4 0.56 9.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Arch_ATPase PF01637.13 KPI43552.1 - 0.00041 20.1 0.1 0.32 10.6 0.0 3.0 3 0 0 3 3 3 1 Archaeal ATPase RNA_helicase PF00910.17 KPI43552.1 - 0.00065 19.8 0.0 2.3 8.4 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 KPI43552.1 - 0.00069 19.6 0.0 0.55 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KPI43552.1 - 0.00098 18.8 0.9 0.022 14.4 0.1 2.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 KPI43552.1 - 0.0011 18.7 0.2 1.1 8.9 0.2 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KPI43552.1 - 0.0014 18.0 0.0 0.45 9.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KPI43552.1 - 0.0015 18.0 0.4 0.41 10.0 0.2 2.5 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 KPI43552.1 - 0.0019 18.0 0.1 0.15 11.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 KPI43552.1 - 0.003 17.4 0.1 2.9 7.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.18 KPI43552.1 - 0.0048 16.7 0.0 1.2 8.8 0.0 3.2 3 0 0 3 3 3 1 Dynamin family SbcCD_C PF13558.1 KPI43552.1 - 0.0049 16.7 0.2 0.91 9.4 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 KPI43552.1 - 0.0073 15.2 0.6 1.7 7.4 0.0 3.1 3 1 0 3 3 3 1 NB-ARC domain ABC_ATPase PF09818.4 KPI43552.1 - 0.0077 14.8 0.0 11 4.5 0.0 3.4 3 1 0 3 3 3 0 Predicted ATPase of the ABC class DAP3 PF10236.4 KPI43552.1 - 0.0084 15.0 0.1 2.5 6.9 0.0 2.6 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 DUF2813 PF11398.3 KPI43552.1 - 0.015 14.4 0.0 5.3 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) PduV-EutP PF10662.4 KPI43552.1 - 0.041 13.3 0.1 3 7.3 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 KPI43552.1 - 0.044 12.7 0.0 2.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 KPI43552.1 - 0.053 13.0 0.0 0.43 10.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Pcc1 PF09341.5 KPI43553.1 - 1.5e-24 85.8 0.1 2.3e-24 85.2 0.1 1.3 1 1 0 1 1 1 1 Transcription factor Pcc1 HhH-GPD PF00730.20 KPI43554.1 - 5.2e-18 65.3 0.0 1.2e-17 64.1 0.0 1.6 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KPI43554.1 - 4.9e-07 29.0 0.0 1.9e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif DNA_primase_lrg PF04104.9 KPI43555.1 - 1.5e-83 280.0 0.0 2.4e-83 279.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit PBP PF01161.15 KPI43557.1 - 2e-25 89.3 0.3 2.9e-25 88.7 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF883 PF05957.8 KPI43558.1 - 0.0062 16.9 4.8 0.012 15.9 3.3 1.6 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) DUF1490 PF07371.7 KPI43558.1 - 0.0066 16.3 5.6 0.0066 16.3 3.9 2.2 3 1 1 4 4 4 1 Protein of unknown function (DUF1490) CAF-1_p150 PF11600.3 KPI43558.1 - 0.042 13.2 11.6 0.056 12.8 8.1 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2229 PF09989.4 KPI43558.1 - 0.1 12.0 1.2 0.12 11.8 0.8 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Ribosomal_L19e PF01280.15 KPI43558.1 - 0.16 11.7 5.4 0.22 11.2 3.7 1.1 1 0 0 1 1 1 0 Ribosomal protein L19e GAGA_bind PF06217.7 KPI43558.1 - 0.22 11.4 3.0 0.24 11.3 2.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DHHW PF14286.1 KPI43558.1 - 1.7 7.8 4.7 2.3 7.4 3.3 1.2 1 0 0 1 1 1 0 DHHW protein DUF3435 PF11917.3 KPI43558.1 - 2.1 6.9 5.2 2.7 6.6 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) ATP-synt_B PF00430.13 KPI43558.1 - 2.2 8.1 14.2 3.5 7.4 9.8 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) vATP-synt_E PF01991.13 KPI43558.1 - 6.8 5.9 13.3 10 5.3 9.2 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Pectate_lyase_3 PF12708.2 KPI43559.1 - 2.3e-48 165.2 20.3 3.2e-38 132.1 7.4 3.4 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KPI43559.1 - 0.00011 21.5 1.2 0.44 10.0 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase zf-CCCH PF00642.19 KPI43560.1 - 5.3e-11 41.9 4.6 2.4e-05 23.9 0.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.16 KPI43560.1 - 6.3e-11 42.3 0.1 2e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 KPI43560.1 - 4.7e-09 36.1 4.5 9.3e-09 35.1 3.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) HBS1_N PF08938.5 KPI43560.1 - 0.0051 16.8 0.0 0.017 15.2 0.0 1.8 1 0 0 1 1 1 1 HBS1 N-terminus CUE PF02845.11 KPI43560.1 - 0.17 11.4 0.1 0.39 10.2 0.1 1.6 1 0 0 1 1 1 0 CUE domain zf-CCCH_2 PF14608.1 KPI43560.1 - 1.9 8.5 5.0 0.32 11.0 0.4 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Rib_recp_KP_reg PF05104.7 KPI43560.1 - 3.3 8.2 8.9 4.8 7.6 3.2 2.7 3 0 0 3 3 3 0 Ribosome receptor lysine/proline rich region CLASP_N PF12348.3 KPI43561.1 - 6.1e-34 117.3 0.0 1.1e-33 116.5 0.0 1.4 1 0 0 1 1 1 1 CLASP N terminal p450 PF00067.17 KPI43562.1 - 9.9e-63 212.2 0.0 1.3e-62 211.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DHDPS PF00701.17 KPI43563.1 - 5.7e-33 113.7 0.0 1e-25 89.9 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family Apc5 PF12862.2 KPI43564.1 - 1.2e-36 124.3 2.0 4.2e-36 122.6 1.4 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 Cohesin_load PF10345.4 KPI43564.1 - 0.00036 18.8 2.2 0.011 14.0 0.0 2.2 2 0 0 2 2 2 2 Cohesin loading factor TPR_14 PF13428.1 KPI43564.1 - 0.0097 16.4 5.0 10 7.0 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.4 KPI43564.1 - 0.017 14.4 0.1 5.4 6.3 0.0 3.1 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_19 PF14559.1 KPI43564.1 - 0.075 13.3 11.1 8.7 6.7 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KPI43564.1 - 0.12 13.0 14.5 1.1 10.0 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Cupin_2 PF07883.6 KPI43565.1 - 1.9e-11 43.2 0.3 3e-11 42.6 0.2 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KPI43565.1 - 0.00076 19.1 0.1 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain DUF1498 PF07385.7 KPI43565.1 - 0.019 14.0 0.0 0.26 10.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1498) MannoseP_isomer PF01050.13 KPI43565.1 - 0.023 14.3 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase HAD_2 PF13419.1 KPI43566.1 - 6.1e-17 62.3 0.0 1.1e-16 61.6 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KPI43566.1 - 0.0003 20.4 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HCO3_cotransp PF00955.16 KPI43567.1 - 1.2e-59 202.3 16.5 5.6e-39 134.1 3.4 2.1 1 1 1 2 2 2 2 HCO3- transporter family Glyco_hydro_32N PF00251.15 KPI43568.1 - 3.4e-43 148.1 0.4 5.8e-43 147.4 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KPI43568.1 - 0.09 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 KPI43568.1 - 0.2 11.6 0.3 0.2 11.6 0.2 2.8 2 0 0 2 2 2 0 BNR/Asp-box repeat F-box-like_2 PF13013.1 KPI43569.1 - 0.016 14.9 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain PPR_2 PF13041.1 KPI43570.1 - 5.7e-22 77.4 0.6 2.5e-11 43.3 0.0 5.7 3 1 2 5 5 5 4 PPR repeat family PPR PF01535.15 KPI43570.1 - 3.3e-17 61.1 4.7 0.0017 18.1 0.0 8.2 8 0 0 8 8 8 5 PPR repeat PPR_3 PF13812.1 KPI43570.1 - 1.5e-16 59.2 10.8 0.0005 20.1 0.0 9.8 11 0 0 11 11 11 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 KPI43570.1 - 7.4e-14 50.9 0.6 0.0063 15.9 0.0 5.4 5 0 0 5 5 5 4 PPR repeat ATP13 PF12921.2 KPI43570.1 - 0.00049 19.4 0.4 0.037 13.3 0.0 3.1 2 1 1 3 3 3 1 Mitochondrial ATPase expression RNase_PH PF01138.16 KPI43571.1 - 4e-09 36.8 0.0 5.6e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KPI43571.1 - 0.0068 16.3 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 SAICAR_synt PF01259.13 KPI43572.1 - 2.3e-81 272.5 0.0 2.9e-80 268.9 0.0 1.9 1 1 0 1 1 1 1 SAICAR synthetase Glyco_transf_41 PF13844.1 KPI43573.1 - 4e-91 305.3 1.5 1.9e-43 148.1 0.0 3.5 4 0 0 4 4 4 3 Glycosyl transferase family 41 TPR_11 PF13414.1 KPI43573.1 - 3.7e-23 80.9 14.0 8.6e-10 38.1 1.8 4.8 3 1 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 KPI43573.1 - 5.3e-18 63.4 10.0 0.00023 20.8 0.2 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 KPI43573.1 - 9.7e-17 59.8 11.8 0.00017 21.0 0.1 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KPI43573.1 - 1.8e-13 50.7 10.5 1.7e-07 31.7 2.1 4.6 4 1 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KPI43573.1 - 1.4e-12 47.0 9.1 0.0012 19.3 0.1 6.0 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KPI43573.1 - 1e-11 44.5 11.3 0.00018 21.3 2.7 4.8 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 KPI43573.1 - 3.1e-11 42.5 9.0 0.094 12.9 0.2 5.6 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 KPI43573.1 - 7.1e-11 41.0 2.9 0.22 11.3 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KPI43573.1 - 3.7e-10 39.9 6.2 1.2e-05 25.4 1.7 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 KPI43573.1 - 4.1e-10 39.2 16.7 0.01 15.7 1.2 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 KPI43573.1 - 4.4e-09 35.4 4.7 0.025 14.3 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 KPI43573.1 - 0.0033 17.5 2.8 0.11 12.6 0.9 3.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KPI43573.1 - 0.0039 17.5 9.0 2.5 8.7 0.3 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.12 KPI43573.1 - 0.009 16.3 4.3 4.7 7.5 1.1 3.3 3 0 0 3 3 3 2 Bacterial transcriptional activator domain TPR_9 PF13371.1 KPI43573.1 - 0.013 15.2 1.9 8.1 6.3 0.7 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KPI43573.1 - 1.2 9.7 6.2 3.5 8.3 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat MS_channel PF00924.13 KPI43574.1 - 1.8e-17 63.3 0.6 3.9e-17 62.2 0.4 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KPI43574.1 - 0.0027 16.8 0.8 0.0055 15.9 0.2 1.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 KPI43574.1 - 0.024 13.9 0.2 0.054 12.8 0.1 1.5 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 KPI43574.1 - 0.064 13.1 0.2 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain Fungal_trans_2 PF11951.3 KPI43575.1 - 8.9e-40 136.4 5.6 1.3e-39 135.8 3.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Iso_dh PF00180.15 KPI43576.1 - 1.1e-78 264.6 0.0 1.2e-78 264.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Abhydrolase_3 PF07859.8 KPI43577.1 - 3.3e-33 115.0 0.0 4.8e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KPI43577.1 - 2.9e-06 26.3 0.0 4.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KPI43577.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KPI43577.1 - 0.026 13.9 0.0 0.081 12.3 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KPI43577.1 - 0.11 11.7 0.0 11 5.1 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Methyltransf_4 PF02390.12 KPI43577.1 - 0.29 10.1 0.5 0.52 9.3 0.4 1.3 1 0 0 1 1 1 0 Putative methyltransferase WD40 PF00400.27 KPI43579.1 - 2.8e-41 137.9 15.0 4.6e-08 32.6 0.0 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 KPI43579.1 - 4.1e-09 36.0 1.2 9.6e-09 34.8 0.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KPI43579.1 - 3.9e-08 32.7 0.6 9.9e-08 31.4 0.4 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KPI43579.1 - 0.00087 17.5 0.8 0.51 8.3 0.0 3.0 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KPI43579.1 - 0.28 9.8 5.0 25 3.4 0.1 3.9 1 1 2 3 3 3 0 Nup133 N terminal like S10_plectin PF03501.10 KPI43580.1 - 6.2e-41 138.1 0.1 7.4e-41 137.9 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain MFS_1 PF07690.11 KPI43581.1 - 8.1e-15 54.3 31.6 7e-13 48.0 19.7 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI43581.1 - 0.003 16.2 2.1 0.003 16.2 1.5 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Ank_2 PF12796.2 KPI43582.1 - 2.2e-11 43.9 0.2 4.1e-09 36.6 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KPI43582.1 - 1.1e-10 41.7 0.5 2.6e-06 27.7 0.1 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 KPI43582.1 - 2.5e-10 39.6 0.4 1.3e-08 34.1 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 KPI43582.1 - 2.4e-07 30.7 0.2 1e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KPI43582.1 - 3.3e-05 23.7 0.0 0.00046 20.1 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat UcrQ PF02939.11 KPI43583.1 - 7.3e-31 105.8 0.1 8.9e-31 105.5 0.0 1.1 1 0 0 1 1 1 1 UcrQ family zf-C2H2 PF00096.21 KPI43585.1 - 3.3e-05 23.9 12.4 0.012 15.8 1.0 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI43585.1 - 7.6e-05 22.7 16.8 0.00065 19.8 1.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KPI43585.1 - 0.28 11.5 18.6 2.3 8.6 1.0 4.0 4 0 0 4 4 4 0 Zinc-finger double domain Pex14_N PF04695.8 KPI43586.1 - 4.4e-16 59.1 0.0 4.4e-16 59.1 0.0 2.9 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PhyH PF05721.8 KPI43589.1 - 2.6e-28 99.4 0.1 3.8e-28 98.9 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.1 KPI43589.1 - 9.3e-06 26.0 0.1 2.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 KPI43589.1 - 0.0001 22.5 0.0 0.0002 21.5 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Crystall PF00030.14 KPI43589.1 - 0.0099 15.7 0.1 0.02 14.7 0.0 1.4 1 0 0 1 1 1 1 Beta/Gamma crystallin CBM_3 PF00942.13 KPI43589.1 - 0.067 13.2 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Cellulose binding domain Baculo_PEP_C PF04513.7 KPI43590.1 - 0.088 12.6 0.2 0.088 12.6 0.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1776 PF08643.5 KPI43590.1 - 0.17 11.0 0.4 0.2 10.7 0.3 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ETRAMP PF09716.5 KPI43590.1 - 1.5 8.8 9.2 2 8.4 0.2 2.7 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Herpes_US9 PF06072.6 KPI43590.1 - 4.5 7.1 5.2 0.71 9.7 0.1 2.3 2 1 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Mit_KHE1 PF10173.4 KPI43591.1 - 2.2e-38 132.0 0.0 5.8e-38 130.6 0.0 1.6 1 1 1 2 2 2 1 Mitochondrial K+-H+ exchange-related Prok-E2_E PF14462.1 KPI43591.1 - 0.012 15.1 0.2 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family E C1_1 PF00130.17 KPI43592.1 - 0.061 13.0 1.0 0.11 12.2 0.7 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Nab2 PF11517.3 KPI43593.1 - 0.00011 22.1 0.9 0.00021 21.3 0.1 1.8 2 1 0 2 2 2 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Glyco_tran_WbsX PF14307.1 KPI43594.1 - 2.3e-60 204.6 8.9 7.8e-33 114.0 0.1 3.2 1 1 2 3 3 3 3 Glycosyltransferase WbsX DASH_Dad2 PF08654.5 KPI43594.1 - 0.034 14.1 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad2 YqjK PF13997.1 KPI43594.1 - 8 6.7 6.8 6 7.1 0.0 3.3 3 0 0 3 3 3 0 YqjK-like protein RICTOR_phospho PF14665.1 KPI43595.1 - 0.11 12.6 0.6 0.68 10.0 0.0 2.3 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site Ribosomal_L22e PF01776.12 KPI43598.1 - 2.6e-50 169.1 0.4 3.1e-50 168.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family E1-E2_ATPase PF00122.15 KPI43599.1 - 1.2e-56 191.3 0.3 2.6e-56 190.2 0.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KPI43599.1 - 7e-45 152.7 4.9 7e-45 152.7 3.4 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KPI43599.1 - 1.3e-28 100.9 0.5 2.8e-28 99.8 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KPI43599.1 - 6.3e-16 58.1 0.0 1.3e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KPI43599.1 - 7.4e-13 49.0 0.0 1.8e-12 47.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KPI43599.1 - 2.9e-07 30.3 0.4 0.00013 21.6 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KPI43599.1 - 2.6e-06 26.7 0.0 7.5e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus His_Phos_1 PF00300.17 KPI43600.1 - 3.9e-26 92.0 0.0 5e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) VD10_N PF08476.5 KPI43600.1 - 0.014 14.8 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 Viral D10 N-terminal GAF_2 PF13185.1 KPI43601.1 - 1.1e-09 38.9 0.0 1.3e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 KPI43601.1 - 3.2e-07 30.6 0.0 4.6e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 KPI43601.1 - 0.0081 16.2 0.0 0.01 15.9 0.0 1.4 1 1 0 1 1 1 1 GAF domain BAR PF03114.13 KPI43602.1 - 1.1e-61 208.2 3.9 1.5e-61 207.8 2.7 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KPI43602.1 - 4.3e-15 54.8 0.1 8.7e-15 53.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KPI43602.1 - 2.1e-12 46.4 0.1 3.9e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KPI43602.1 - 3.2e-10 39.3 0.0 6.7e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 KPI43602.1 - 0.022 14.0 4.8 3.1 6.9 2.2 2.3 2 0 0 2 2 2 0 Vps5 C terminal like GCV_H PF01597.14 KPI43602.1 - 0.065 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein Sugar_tr PF00083.19 KPI43603.1 - 1.2e-129 432.8 20.4 1.3e-129 432.6 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI43603.1 - 5.2e-26 91.1 51.5 4.9e-23 81.4 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 KPI43603.1 - 0.14 12.1 3.7 0.19 11.7 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DASH_Ask1 PF08655.5 KPI43604.1 - 2.8e-33 113.5 0.0 4.7e-33 112.8 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 CDK5_activator PF03261.10 KPI43604.1 - 6.3 6.0 13.0 0.053 12.8 3.3 1.7 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein UQ_con PF00179.21 KPI43605.1 - 4.2e-36 123.4 0.0 5.3e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KPI43605.1 - 0.0073 16.1 0.0 0.0085 15.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.6 KPI43605.1 - 0.016 14.6 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.1 KPI43605.1 - 0.018 14.8 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Hexapep PF00132.19 KPI43606.1 - 4.1e-10 38.7 7.0 0.00012 21.4 0.6 4.5 4 0 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KPI43606.1 - 1.9e-05 24.1 2.8 0.092 12.3 1.2 4.0 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Glucosamine_iso PF01182.15 KPI43607.1 - 1.3e-22 80.4 0.0 2e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ribosomal_L18p PF00861.17 KPI43608.1 - 1.4e-41 141.4 0.7 4.6e-41 139.7 0.0 2.0 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KPI43608.1 - 3.7e-33 113.9 9.7 3.7e-33 113.9 6.7 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region ATP_sub_h PF10775.4 KPI43608.1 - 0.097 12.4 1.8 1.7 8.4 0.0 3.2 2 1 1 3 3 3 0 ATP synthase complex subunit h DUF605 PF04652.11 KPI43609.1 - 0.41 9.9 15.7 0.45 9.8 10.9 1.2 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 KPI43609.1 - 6.5 6.5 8.3 7.9 6.2 5.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med21 PF11221.3 KPI43610.1 - 2e-34 118.6 0.7 2.8e-34 118.1 0.5 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex MRP-L20 PF12824.2 KPI43610.1 - 0.00093 19.1 0.6 0.0012 18.8 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Sipho_Gp157 PF05565.6 KPI43610.1 - 0.022 14.3 2.2 0.031 13.8 1.5 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 TMF_DNA_bd PF12329.3 KPI43610.1 - 0.075 12.8 3.6 0.13 12.0 2.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spore_III_AB PF09548.5 KPI43610.1 - 0.12 12.1 1.1 0.18 11.5 0.7 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Med9 PF07544.8 KPI43610.1 - 0.13 12.0 1.9 0.22 11.2 0.4 1.9 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DEAD PF00270.24 KPI43611.1 - 7.1e-33 113.4 0.5 4.6e-31 107.5 0.1 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI43611.1 - 3.1e-21 75.0 0.3 5.9e-21 74.1 0.2 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KPI43611.1 - 0.032 13.9 0.4 0.41 10.4 0.0 2.7 3 0 0 3 3 3 0 Part of AAA domain DUF2999 PF11212.3 KPI43611.1 - 0.066 13.2 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) Transp_cyt_pur PF02133.10 KPI43612.1 - 2.5e-78 263.6 42.2 3.6e-77 259.7 29.3 2.1 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.13 KPI43612.1 - 5.7e-23 81.1 4.3 9.5e-23 80.3 3.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI43612.1 - 0.00073 19.3 8.9 0.0013 18.5 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyrosinase PF00264.15 KPI43615.1 - 5e-36 124.9 0.1 6.7e-36 124.5 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase TrbM PF07424.6 KPI43615.1 - 0.1 12.5 0.1 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 TrbM Cupin_2 PF07883.6 KPI43616.1 - 5.9e-06 25.6 0.3 1.1e-05 24.8 0.2 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KPI43616.1 - 1.5e-05 24.4 0.0 1.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 KPI43616.1 - 7.6e-05 22.4 0.0 9.1e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KPI43616.1 - 0.052 13.2 0.2 0.082 12.5 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain ARD PF03079.9 KPI43616.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Cupin_2 PF07883.6 KPI43618.1 - 1.9e-09 36.9 0.4 2.8e-09 36.3 0.3 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KPI43618.1 - 0.0019 17.6 0.1 0.0024 17.3 0.1 1.3 1 1 0 1 1 1 1 Cupin Ectoine_synth PF06339.7 KPI43618.1 - 0.048 13.5 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Ectoine synthase Fungal_trans PF04082.13 KPI43620.1 - 4.4e-13 48.7 1.8 1.1e-12 47.4 1.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pex14_N PF04695.8 KPI43621.1 - 3 7.8 6.2 3.4 7.7 4.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pex24p PF06398.6 KPI43623.1 - 3.9e-76 256.1 0.0 5.1e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.3 KPI43623.1 - 2.3 5.9 4.8 0.28 9.0 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) Exo70 PF03081.10 KPI43624.1 - 1.8e-54 184.9 0.0 1.4e-53 182.0 0.0 2.0 2 0 0 2 2 2 1 Exo70 exocyst complex subunit BLYB PF05289.6 KPI43624.1 - 0.05 13.4 0.6 0.82 9.5 0.0 3.0 3 0 0 3 3 3 0 Borrelia hemolysin accessory protein muHD PF10291.4 KPI43625.1 - 2.6e-69 233.2 0.0 3.5e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 KPI43625.1 - 1.7e-08 34.5 0.1 8.4e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Fungal_trans PF04082.13 KPI43626.1 - 0.0033 16.3 0.0 0.0043 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PTS_EIIC_2 PF13303.1 KPI43626.1 - 0.14 11.0 0.2 2.2 7.0 0.2 2.0 2 0 0 2 2 2 0 Phosphotransferase system, EIIC Sugar_tr PF00083.19 KPI43627.1 - 4.7e-59 200.1 11.7 8.4e-59 199.3 8.1 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI43627.1 - 9.1e-14 50.9 22.6 9.1e-14 50.9 15.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI43627.1 - 0.0011 17.4 20.9 0.0041 15.5 0.8 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein PTH2 PF01981.11 KPI43628.1 - 2.9e-41 139.7 0.1 4.7e-41 139.1 0.1 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 RFC1 PF08519.7 KPI43629.1 - 4.7e-56 188.8 0.1 1e-55 187.7 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain Nucleo_P87 PF07267.6 KPI43629.1 - 0.00085 18.1 0.9 0.0011 17.7 0.6 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 DUF2151 PF10221.4 KPI43629.1 - 0.19 9.8 1.9 0.28 9.3 1.3 1.4 1 0 0 1 1 1 0 Cell cycle and development regulator Peptidase_M22 PF00814.20 KPI43630.1 - 3e-43 148.2 0.0 2.4e-41 141.9 0.0 2.8 1 1 0 1 1 1 1 Glycoprotease family YycC PF14174.1 KPI43630.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 YycC-like protein RTA1 PF04479.8 KPI43631.1 - 1.2e-45 155.7 5.2 1.9e-45 155.0 3.6 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF588 PF04535.7 KPI43631.1 - 4.1e-07 29.6 2.7 7.2e-06 25.6 0.3 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF588) COX6A PF02046.10 KPI43632.1 - 6.1e-47 158.3 1.0 7.1e-47 158.0 0.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa CtaG_Cox11 PF04442.9 KPI43633.1 - 1.4e-58 197.0 0.1 2.2e-58 196.3 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF2076 PF09849.4 KPI43634.1 - 6.8e-07 29.5 5.0 7.6e-07 29.4 3.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 KPI43634.1 - 0.00037 20.3 3.9 0.00059 19.6 2.7 1.4 1 0 0 1 1 1 1 CHCH domain DUF1517 PF07466.6 KPI43634.1 - 0.042 12.8 1.6 0.06 12.3 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) RAB3GAP2_N PF14655.1 KPI43634.1 - 0.1 11.5 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Gly-zipper_OmpA PF13436.1 KPI43634.1 - 9.3 5.9 12.1 0.53 9.9 3.7 2.1 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Peptidase_C97 PF05903.9 KPI43636.1 - 5.9e-07 29.3 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 KPI43636.1 - 0.0065 16.4 1.1 0.25 11.2 0.8 2.5 1 1 0 1 1 1 1 Lecithin retinol acyltransferase AA_permease PF00324.16 KPI43637.1 - 3e-80 269.8 38.4 7.8e-55 186.0 11.5 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KPI43637.1 - 6.8e-24 84.1 35.8 1.6e-17 63.1 12.0 2.0 2 0 0 2 2 2 2 Amino acid permease 4HBT PF03061.17 KPI43638.1 - 0.0015 18.6 0.1 0.0072 16.4 0.0 2.0 1 1 0 1 1 1 1 Thioesterase superfamily MFS_1 PF07690.11 KPI43639.1 - 5.7e-43 146.9 34.7 5.1e-40 137.2 13.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2404 PF10296.4 KPI43640.1 - 1.8e-28 98.5 0.0 3.2e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 KPI43640.1 - 0.0075 16.4 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 PH domain Drf_GBD PF06371.8 KPI43641.1 - 1.2e-14 54.0 4.8 3.9e-09 36.1 0.0 3.0 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Glyco_tranf_2_3 PF13641.1 KPI43642.1 - 9.1e-31 107.4 0.0 1.4e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KPI43642.1 - 9.4e-17 61.3 0.2 2.3e-16 60.0 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 KPI43642.1 - 5e-10 38.9 0.0 1.3e-09 37.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KPI43642.1 - 6.4e-09 35.7 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.9 KPI43642.1 - 1e-08 33.9 0.8 0.0012 17.2 0.2 2.1 1 1 1 2 2 2 2 Cellulose synthase Acyl_transf_3 PF01757.17 KPI43643.1 - 6.2e-12 44.9 16.1 8.3e-12 44.5 3.0 3.3 4 0 0 4 4 4 3 Acyltransferase family DUF605 PF04652.11 KPI43643.1 - 0.6 9.4 9.9 1 8.7 6.9 1.3 1 0 0 1 1 1 0 Vta1 like DUF1772 PF08592.6 KPI43644.1 - 0.014 15.0 1.9 0.044 13.5 1.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Nucleoplasmin PF03066.10 KPI43645.1 - 0.48 9.9 7.8 0.73 9.3 5.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 KPI43645.1 - 0.52 10.6 8.5 1.1 9.5 5.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 KPI43645.1 - 1.5 8.0 6.0 2.1 7.5 4.2 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 KPI43645.1 - 5 7.4 11.6 8.7 6.6 7.2 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DLH PF01738.13 KPI43647.1 - 6.1e-12 45.2 1.4 1.6e-09 37.4 1.3 2.4 2 1 0 2 2 2 2 Dienelactone hydrolase family DUF202 PF02656.10 KPI43648.1 - 2.1e-24 85.4 1.1 2.1e-24 85.4 0.8 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF202) Cryptochrome_C PF12546.3 KPI43649.1 - 0.02 15.5 1.2 0.02 15.5 0.8 2.4 1 1 2 3 3 3 0 Blue/Ultraviolet sensing protein C terminal RILP PF11461.3 KPI43649.1 - 1 9.5 5.5 0.92 9.7 0.3 2.6 2 1 1 3 3 3 0 Rab interacting lysosomal protein Acetyltransf_7 PF13508.1 KPI43650.1 - 2e-05 24.6 0.0 6.2e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KPI43650.1 - 0.00013 21.9 0.0 0.0006 19.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KPI43650.1 - 0.0036 17.4 0.0 0.0056 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KPI43650.1 - 0.029 14.2 0.1 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KPI43650.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PAN_4 PF14295.1 KPI43652.1 - 0.038 13.6 5.0 0.19 11.4 3.5 2.3 1 0 0 1 1 1 0 PAN domain CBF PF03914.12 KPI43653.1 - 3e-31 108.0 0.0 1.2e-26 93.1 0.0 2.4 1 1 1 2 2 2 2 CBF/Mak21 family Zn_clus PF00172.13 KPI43654.1 - 2.3e-05 24.1 10.5 4.6e-05 23.2 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KPI43654.1 - 0.0011 17.8 0.0 0.0018 17.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dicty_CAR PF05462.6 KPI43655.1 - 1.3e-12 47.2 8.5 2.2e-12 46.5 3.6 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 KPI43655.1 - 1.8e-05 24.3 7.0 3.5e-05 23.4 4.8 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 MMR_HSR1 PF01926.18 KPI43656.1 - 5.4e-17 61.8 0.0 1.1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KPI43656.1 - 0.00022 20.4 0.2 0.0014 17.8 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KPI43656.1 - 0.0012 18.2 0.0 0.0078 15.6 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KPI43656.1 - 0.0061 15.8 0.1 0.012 14.8 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 KPI43656.1 - 0.0066 16.5 0.0 0.019 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 KPI43656.1 - 0.012 14.7 0.0 0.034 13.3 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 KPI43656.1 - 0.015 15.1 0.1 0.3 10.9 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Miro PF08477.8 KPI43656.1 - 0.036 14.5 0.0 4.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein Arch_ATPase PF01637.13 KPI43656.1 - 0.18 11.4 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase BRO1 PF03097.13 KPI43657.1 - 0.00027 19.8 0.0 0.0012 17.7 0.0 1.9 1 1 0 1 1 1 1 BRO1-like domain Fungal_trans PF04082.13 KPI43658.1 - 8.3e-11 41.2 1.4 2.2e-10 39.8 1.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ax_dynein_light PF10211.4 KPI43661.1 - 0.017 14.9 5.9 0.017 14.9 4.1 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain Suppressor_APC PF11414.3 KPI43661.1 - 0.12 12.2 4.7 0.073 12.8 1.8 1.6 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein GAS PF13851.1 KPI43661.1 - 1.6 7.9 17.0 0.35 10.0 1.9 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Zn_clus PF00172.13 KPI43662.1 - 3.4e-09 36.4 6.7 6.9e-09 35.4 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KPI43662.1 - 2.1e-05 23.3 0.1 4.2e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain ApoO PF09769.4 KPI43663.1 - 0.0092 15.6 0.5 0.33 10.6 0.0 2.2 2 0 0 2 2 2 1 Apolipoprotein O COG2 PF06148.6 KPI43663.1 - 0.068 13.0 0.3 0.3 10.9 0.2 2.1 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Mnd1 PF03962.10 KPI43663.1 - 0.073 12.7 3.8 1.4 8.5 0.3 2.2 1 1 1 2 2 2 0 Mnd1 family YlbD_coat PF14071.1 KPI43663.1 - 0.14 12.1 0.3 2.1 8.4 0.1 2.5 1 1 2 3 3 3 0 Putative coat protein G-alpha PF00503.15 KPI43664.1 - 3.5e-115 384.8 6.6 6.3e-100 334.5 0.9 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.16 KPI43664.1 - 5.4e-16 58.3 1.0 1e-10 41.1 0.1 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 KPI43664.1 - 0.00036 20.0 0.0 0.0016 17.9 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 KPI43664.1 - 0.0049 17.3 1.2 3 8.3 0.1 2.6 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 KPI43664.1 - 0.016 14.3 5.3 0.088 11.9 0.1 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KPI43664.1 - 0.019 14.4 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KPI43664.1 - 0.075 12.4 0.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.18 KPI43664.1 - 0.088 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family FtsK_SpoIIIE PF01580.13 KPI43664.1 - 0.091 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 KPI43664.1 - 0.13 12.2 0.0 20 5.1 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase zf-AN1 PF01428.11 KPI43665.1 - 9.4e-10 38.2 4.2 1.4e-09 37.6 2.9 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.3 KPI43665.1 - 0.00047 19.7 0.0 0.00087 18.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Transp_Tc5_C PF04236.10 KPI43665.1 - 0.028 14.6 0.6 0.047 13.9 0.4 1.3 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain DOCK-C2 PF14429.1 KPI43666.1 - 6.8e-26 91.0 0.0 1.2e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.1 KPI43666.1 - 3.3e-05 23.3 0.0 7.8e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KPI43666.1 - 0.02 14.2 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 SH3 domain SH3_2 PF07653.12 KPI43666.1 - 0.086 12.3 0.0 0.23 10.9 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain NAD_kinase PF01513.16 KPI43669.1 - 1.7e-54 184.5 0.0 2e-42 144.9 0.0 2.1 1 1 1 2 2 2 2 ATP-NAD kinase ETF PF01012.16 KPI43670.1 - 9.3e-40 136.0 0.0 2.9e-39 134.4 0.0 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 KPI43670.1 - 8e-21 73.4 0.2 4.4e-19 67.8 0.1 2.6 1 1 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Dynamin_M PF01031.15 KPI43671.1 - 3.8e-114 380.4 0.0 8.9e-114 379.2 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KPI43671.1 - 4e-56 189.4 0.9 9.6e-56 188.1 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 KPI43671.1 - 8e-32 109.0 1.4 2.2e-31 107.6 1.0 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KPI43671.1 - 0.00024 21.0 0.3 0.0026 17.7 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KPI43671.1 - 0.013 16.0 0.0 0.038 14.4 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein zf-CCHC_4 PF14392.1 KPI43671.1 - 0.092 12.4 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle MFS_1 PF07690.11 KPI43672.1 - 1.6e-37 129.0 50.6 1.6e-37 129.0 35.1 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KPI43672.1 - 2.8e-11 42.3 23.6 1.8e-10 39.6 16.4 2.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) IgaA PF07095.6 KPI43672.1 - 0.093 10.4 0.0 0.17 9.6 0.0 1.3 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA CCDC-167 PF15188.1 KPI43672.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Viral_Beta_CD PF04530.7 KPI43672.1 - 0.42 10.7 0.0 0.42 10.7 0.0 2.4 3 0 0 3 3 3 0 Viral Beta C/D like family Chitin_synth_2 PF03142.10 KPI43673.1 - 5.3e-254 843.4 1.1 6.9e-254 843.1 0.8 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KPI43673.1 - 4e-168 560.5 0.0 6.7e-168 559.8 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 KPI43673.1 - 2.9e-15 55.8 0.0 1e-09 38.0 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 KPI43673.1 - 8.9e-15 54.2 0.6 3.1e-14 52.4 0.4 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 KPI43673.1 - 2.5e-14 53.4 4.5 2.5e-14 53.4 3.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KPI43673.1 - 3.9e-14 52.9 0.0 2.1e-10 40.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KPI43673.1 - 3.4e-05 23.5 0.0 0.0061 16.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KPI43673.1 - 0.00061 19.1 0.1 0.019 14.2 0.0 2.9 3 0 0 3 3 3 1 Glycosyl transferase family 21 AAA_22 PF13401.1 KPI43673.1 - 0.016 15.3 0.0 0.075 13.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KPI43673.1 - 0.11 12.7 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KPI43673.1 - 0.14 11.3 0.0 0.48 9.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2592 PF10766.4 KPI43673.1 - 0.17 11.2 2.5 0.46 9.8 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) Med16 PF11635.3 KPI43674.1 - 1.1e-05 23.6 0.4 1.3e-05 23.4 0.3 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 fn1 PF00039.13 KPI43674.1 - 0.027 14.2 0.5 0.059 13.1 0.4 1.5 1 0 0 1 1 1 0 Fibronectin type I domain GATase_7 PF13537.1 KPI43675.1 - 3.6e-07 29.9 0.0 2.5e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KPI43675.1 - 1.7e-05 24.8 0.0 0.00011 22.1 0.0 2.1 2 1 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KPI43675.1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein GATase_2 PF00310.16 KPI43675.1 - 0.072 11.7 0.0 0.64 8.6 0.0 2.0 1 1 0 2 2 2 0 Glutamine amidotransferases class-II AAT PF03417.11 KPI43676.1 - 1.4e-23 83.5 0.0 1.9e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 KPI43676.1 - 1.7e-05 25.1 0.0 3.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Gly_transf_sug PF04488.10 KPI43677.1 - 1e-10 41.8 0.1 2.2e-10 40.8 0.1 1.5 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KPI43677.1 - 0.02 14.0 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein MFS_1 PF07690.11 KPI43678.1 - 9.2e-36 123.2 31.5 2.7e-35 121.7 22.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3390 PF11870.3 KPI43678.1 - 0.037 13.9 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) Ish1 PF10281.4 KPI43679.1 - 2.5e-75 248.1 23.3 4.1e-14 52.3 0.0 7.7 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 KPI43679.1 - 2.6e-15 55.6 0.0 4.1e-05 23.0 0.1 5.2 5 0 0 5 5 5 2 HeH/LEM domain SAP PF02037.22 KPI43679.1 - 2e-13 49.5 0.0 1 8.9 0.0 7.8 7 2 0 7 7 7 4 SAP domain APC2 PF08672.6 KPI43679.1 - 2.8e-06 27.4 3.1 7.9 6.8 0.0 6.5 7 0 0 7 7 7 1 Anaphase promoting complex (APC) subunit 2 Slx4 PF09494.5 KPI43679.1 - 0.00018 21.1 0.6 6.5 6.5 0.0 5.6 7 0 0 7 7 7 1 Slx4 endonuclease DUF3612 PF12268.3 KPI43679.1 - 0.0056 16.4 0.1 9.6 5.9 0.0 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF3612) DUF3231 PF11553.3 KPI43679.1 - 0.12 11.8 0.0 46 3.4 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3231) Isochorismatase PF00857.15 KPI43679.1 - 0.13 12.2 1.2 1.5e+02 2.2 0.0 4.8 5 1 1 6 6 6 0 Isochorismatase family DUF2795 PF11387.3 KPI43679.1 - 1.7 8.5 11.1 27 4.7 0.1 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2795) SAM_2 PF07647.12 KPI43679.1 - 3.7 7.4 5.9 81 3.1 0.0 4.4 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) DUF883 PF05957.8 KPI43679.1 - 9.2 6.7 14.4 3.5 8.1 1.0 4.0 5 1 0 5 5 4 0 Bacterial protein of unknown function (DUF883) Sld5 PF05916.6 KPI43680.1 - 1.4e-14 54.2 0.3 2.8e-14 53.2 0.2 1.5 2 0 0 2 2 2 1 GINS complex protein zf-MYND PF01753.13 KPI43681.1 - 1.5e-08 34.3 7.0 2.7e-08 33.5 4.8 1.5 1 0 0 1 1 1 1 MYND finger dsDNA_bind PF01984.15 KPI43682.1 - 2.4e-32 111.0 10.5 3.6e-32 110.5 7.3 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF3818 PF12825.2 KPI43682.1 - 0.0075 14.9 0.7 0.0084 14.8 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) DUF4615 PF15393.1 KPI43682.1 - 0.017 15.3 2.8 0.017 15.3 1.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) EF-1_beta_acid PF10587.4 KPI43682.1 - 0.18 11.9 1.0 0.18 11.9 0.7 2.8 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region DUF1014 PF06244.7 KPI43682.1 - 0.34 11.1 4.2 0.065 13.4 0.8 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1014) Med4 PF10018.4 KPI43682.1 - 1.8 7.9 10.7 0.5 9.7 3.4 2.0 1 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 GAT PF03127.9 KPI43683.1 - 3.8e-14 52.4 0.1 8e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 KPI43683.1 - 0.00091 18.8 0.0 0.002 17.7 0.0 1.6 2 0 0 2 2 2 1 VHS domain DDE_Tnp_1_assoc PF13808.1 KPI43683.1 - 0.11 12.1 0.0 0.37 10.4 0.0 1.8 1 0 0 1 1 1 0 DDE_Tnp_1-associated FHA PF00498.21 KPI43684.1 - 3.9e-15 55.7 0.0 7.7e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Acyl-CoA_dh_C PF12806.2 KPI43684.1 - 0.31 10.8 0.1 0.31 10.8 0.0 2.3 3 0 0 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like DUF3349 PF11829.3 KPI43684.1 - 4.4 7.8 6.3 32 5.0 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3349) DUF1515 PF07439.6 KPI43684.1 - 4.4 7.1 8.5 0.27 11.0 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Myosin_tail_1 PF01576.14 KPI43684.1 - 6 4.4 20.9 0.063 11.0 2.2 2.4 3 0 0 3 3 3 0 Myosin tail CDC73 PF05179.9 KPI43685.1 - 6.6e-44 150.3 0.1 4.7e-43 147.5 0.1 1.9 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family eIF-5a PF01287.15 KPI43686.1 - 1.9e-26 91.7 3.6 2.8e-26 91.2 2.5 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KPI43686.1 - 4.1e-05 23.1 0.7 4.1e-05 23.1 0.5 1.9 2 0 0 2 2 2 1 KOW motif EFP_N PF08207.7 KPI43686.1 - 0.0021 17.8 0.1 0.0049 16.7 0.0 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Nitro_FeMo-Co PF02579.12 KPI43686.1 - 0.0024 17.8 0.2 0.0084 16.1 0.0 1.9 2 0 0 2 2 2 1 Dinitrogenase iron-molybdenum cofactor DUF3431 PF11913.3 KPI43688.1 - 7.9e-83 277.3 0.2 1e-82 276.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Fungal_trans_2 PF11951.3 KPI43689.1 - 4.1e-46 157.3 8.9 4.9e-46 157.0 6.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain NESP55 PF06390.7 KPI43689.1 - 0.3 10.4 1.4 9.1 5.5 0.0 3.1 3 1 1 4 4 4 0 Neuroendocrine-specific golgi protein P55 (NESP55) Fungal_trans_2 PF11951.3 KPI43690.1 - 4.5e-11 41.9 0.1 6.8e-11 41.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI43690.1 - 1.5e-08 34.4 5.7 2.6e-08 33.6 3.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E1-E2_ATPase PF00122.15 KPI43692.1 - 5.9e-61 205.4 0.1 5.9e-61 205.4 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KPI43692.1 - 5.7e-45 153.0 11.6 5.7e-45 153.0 8.0 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KPI43692.1 - 4.1e-26 92.7 0.0 1.6e-25 90.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KPI43692.1 - 1.3e-16 60.3 0.0 2.6e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KPI43692.1 - 1.4e-12 48.1 0.0 4.1e-12 46.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KPI43692.1 - 6.2e-11 41.6 0.2 2.9e-09 36.2 0.0 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KPI43692.1 - 0.00065 19.3 0.1 0.006 16.1 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.19 KPI43693.1 - 3.8e-76 256.4 23.3 4.4e-76 256.2 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI43693.1 - 5.5e-27 94.4 30.1 1.2e-23 83.3 12.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KPI43693.1 - 8.3e-08 30.8 0.7 8.3e-08 30.8 0.5 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KPI43693.1 - 3.6e-06 25.6 1.4 3.6e-06 25.6 1.0 3.0 2 1 0 2 2 2 1 MFS/sugar transport protein DUF4293 PF14126.1 KPI43693.1 - 0.016 15.1 1.2 0.048 13.5 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF2108 PF09881.4 KPI43693.1 - 9.2 6.1 8.7 0.18 11.6 1.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2108) HhH-GPD PF00730.20 KPI43694.1 - 1.3e-13 51.1 0.0 2.2e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF3658 PF12395.3 KPI43696.1 - 0.13 11.7 0.4 0.27 10.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF2937 PF11157.3 KPI43696.1 - 0.16 11.3 1.7 3.2 7.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) zf-met PF12874.2 KPI43697.1 - 1e-05 25.5 1.1 3.6e-05 23.7 0.4 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 KPI43697.1 - 0.054 12.7 0.9 0.092 12.0 0.6 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Snf7 PF03357.16 KPI43698.1 - 3.6e-17 62.2 4.4 4.6e-17 61.9 3.0 1.1 1 0 0 1 1 1 1 Snf7 Mmp37 PF09139.6 KPI43698.1 - 0.12 11.3 1.3 0.17 10.9 0.9 1.2 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Fibrillarin PF01269.12 KPI43699.1 - 1.3e-56 191.0 0.0 2.5e-36 124.7 0.0 2.1 1 1 1 2 2 2 2 Fibrillarin Sugar_tr PF00083.19 KPI43700.1 - 9.7e-94 314.4 27.0 1.4e-93 313.9 18.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI43700.1 - 7.3e-14 51.2 45.9 2.9e-10 39.4 10.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fe_hyd_lg_C PF02906.9 KPI43702.1 - 8.6e-54 182.7 0.0 1.9e-53 181.5 0.0 1.6 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Arf PF00025.16 KPI43704.1 - 1.5e-28 99.1 0.6 1.4e-15 56.9 0.2 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.5 KPI43704.1 - 0.00016 20.9 0.0 0.00019 20.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 KPI43704.1 - 0.0026 17.6 0.0 0.0034 17.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KPI43704.1 - 0.021 13.9 0.0 0.022 13.8 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin 6PF2K PF01591.13 KPI43704.1 - 0.023 13.7 0.1 0.028 13.4 0.1 1.3 1 1 0 1 1 1 0 6-phosphofructo-2-kinase G-alpha PF00503.15 KPI43704.1 - 0.074 11.7 0.1 0.14 10.8 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit SRP54 PF00448.17 KPI43704.1 - 0.15 11.4 0.4 0.25 10.7 0.1 1.4 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DUF605 PF04652.11 KPI43705.1 - 1.7 7.9 22.7 2.5 7.3 15.8 1.3 1 0 0 1 1 1 0 Vta1 like Cyclase PF04199.8 KPI43706.1 - 4.4e-07 29.7 0.1 8.8e-07 28.7 0.1 1.5 1 1 0 1 1 1 1 Putative cyclase adh_short PF00106.20 KPI43707.1 - 2.9e-13 50.0 0.3 5.8e-13 49.0 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI43707.1 - 1.2e-07 31.5 0.1 2.3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI43707.1 - 0.00028 20.7 0.1 0.0005 19.9 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 KPI43707.1 - 0.092 12.8 0.1 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sas10_Utp3 PF04000.10 KPI43708.1 - 4.8e-14 52.3 1.6 4.8e-14 52.3 1.1 2.6 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Fungal_trans PF04082.13 KPI43710.1 - 5.3e-19 68.1 0.0 8.1e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_S11 PF00411.14 KPI43711.1 - 0.00012 22.2 0.0 0.0011 19.1 0.0 2.3 1 1 1 2 2 2 1 Ribosomal protein S11 DUF1880 PF08976.6 KPI43711.1 - 0.057 13.5 0.4 0.057 13.5 0.3 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1880) DUF566 PF04484.7 KPI43711.1 - 8 5.8 11.7 13 5.1 8.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) SPT16 PF08644.6 KPI43712.1 - 1.3e-58 197.2 0.1 1.3e-58 197.2 0.0 2.5 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KPI43712.1 - 6.9e-49 165.5 0.4 6.9e-49 165.5 0.3 1.9 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 KPI43712.1 - 1.5e-22 80.1 0.1 3e-22 79.2 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 Rtt106 PF08512.7 KPI43712.1 - 4.6e-18 64.9 0.0 1.4e-17 63.4 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like GST_C PF00043.20 KPI43714.1 - 5e-13 48.8 0.0 8.1e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KPI43714.1 - 2.3e-09 37.6 0.0 3.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KPI43714.1 - 1.5e-08 34.7 0.0 2.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KPI43714.1 - 6.9e-07 29.0 0.2 3e-06 27.0 0.1 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KPI43714.1 - 4.7e-06 26.5 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KPI43714.1 - 5.1e-05 23.3 0.0 9.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF1744 PF08490.7 KPI43715.1 - 1e-141 472.1 0.2 1.5e-141 471.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 KPI43715.1 - 1.8e-66 224.2 1.5 5.8e-66 222.5 1.0 2.0 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KPI43715.1 - 1.8e-23 83.0 0.0 1.1e-22 80.4 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KPI43715.1 - 2.7e-08 33.6 0.1 8.2e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KPI43715.1 - 0.00017 21.4 0.0 0.00057 19.7 0.0 1.9 1 0 0 1 1 1 1 RNase_H superfamily Transferase PF02458.10 KPI43716.1 - 3.4e-20 71.8 0.0 3.4e-15 55.4 0.0 2.8 2 1 0 2 2 2 2 Transferase family HEAT PF02985.17 KPI43717.1 - 8.2e-17 59.7 9.3 0.0012 18.7 0.0 8.6 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.1 KPI43717.1 - 1.6e-15 57.1 1.8 4.5e-05 23.6 0.0 6.7 3 2 4 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 KPI43717.1 - 4.6e-08 33.3 13.7 0.00088 19.6 0.0 8.4 7 3 2 9 9 9 3 HEAT-like repeat CLASP_N PF12348.3 KPI43717.1 - 9.5e-05 21.8 0.1 0.51 9.6 0.0 4.0 3 0 0 3 3 3 1 CLASP N terminal TIP120 PF08623.5 KPI43717.1 - 0.059 12.9 0.2 2.8 7.5 0.0 3.7 4 1 0 5 5 5 0 TATA-binding protein interacting (TIP20) Arm PF00514.18 KPI43717.1 - 0.1 12.4 2.6 11 6.0 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF3385 PF11865.3 KPI43717.1 - 0.11 12.4 1.7 9.4 6.1 0.0 3.7 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) DUF3431 PF11913.3 KPI43718.1 - 4.7e-18 65.4 0.0 2.3e-17 63.2 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) IKI3 PF04762.7 KPI43719.1 - 4.9e-109 365.5 0.0 5.8e-109 365.3 0.0 1.0 1 0 0 1 1 1 1 IKI3 family Mod_r PF07200.8 KPI43720.1 - 7.6e-11 42.1 0.6 1.2e-10 41.4 0.4 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein CENP-Q PF13094.1 KPI43720.1 - 0.0038 17.2 2.8 0.0056 16.7 1.9 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Spc24 PF08286.6 KPI43720.1 - 0.023 14.4 1.2 0.036 13.7 0.9 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF755 PF05501.6 KPI43720.1 - 0.085 12.9 3.1 0.15 12.1 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) 2OG-FeII_Oxy PF03171.15 KPI43721.1 - 0.02 15.1 0.0 0.064 13.5 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.9 KPI43722.1 - 2.8e-13 50.0 0.1 9.5e-13 48.3 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase FAT PF02259.18 KPI43723.1 - 6.3e-107 357.5 1.4 2.1e-106 355.8 0.8 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 KPI43723.1 - 3.6e-59 200.1 0.7 6.3e-59 199.3 0.5 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 KPI43723.1 - 1.5e-52 177.7 4.1 6.9e-52 175.5 0.1 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 KPI43723.1 - 1.6e-39 133.9 0.0 1.6e-39 133.9 0.0 3.0 3 0 0 3 3 3 1 Rapamycin binding domain FATC PF02260.15 KPI43723.1 - 8.2e-16 57.1 0.0 2.1e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 KPI43723.1 - 1.5e-14 54.0 15.4 0.00021 21.4 0.0 8.3 6 1 0 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 KPI43723.1 - 5.6e-08 33.0 15.5 0.083 13.4 0.2 10.0 8 2 3 11 11 11 2 HEAT-like repeat HEAT PF02985.17 KPI43723.1 - 1.2e-06 28.1 17.9 0.65 10.2 0.1 10.2 12 0 0 12 12 12 2 HEAT repeat MMS19_C PF12460.3 KPI43723.1 - 0.25 9.9 0.0 0.25 9.9 0.0 5.1 6 1 1 7 7 7 0 RNAPII transcription regulator C-terminal OTU PF02338.14 KPI43724.1 - 4.5e-14 53.0 0.0 7.6e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KPI43724.1 - 0.0017 17.7 0.0 0.0029 16.9 0.0 1.4 1 1 0 1 1 1 1 Peptidase C65 Otubain ubiquitin PF00240.18 KPI43724.1 - 0.11 11.9 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin family DUF2183 PF09949.4 KPI43725.1 - 8.6e-19 67.3 0.1 1.5e-18 66.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) SET PF00856.23 KPI43726.1 - 1.4e-12 48.1 0.0 8.2e-12 45.7 0.0 2.1 1 1 0 1 1 1 1 SET domain FAM178 PF14816.1 KPI43726.1 - 0.11 11.2 0.0 0.21 10.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function, FAM178 Ank_5 PF13857.1 KPI43727.1 - 4.5e-18 64.8 0.0 6e-11 42.2 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) VPS9 PF02204.13 KPI43727.1 - 2.4e-16 59.6 0.0 5.9e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 KPI43727.1 - 2.1e-13 50.4 0.0 1e-06 28.9 0.0 3.1 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KPI43727.1 - 7.1e-10 39.1 0.0 0.0038 17.6 0.0 4.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 KPI43727.1 - 1.6e-09 37.0 0.1 0.0083 15.8 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KPI43727.1 - 1.7e-08 33.8 0.1 0.87 10.0 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat PX PF00787.19 KPI43727.1 - 2.9e-05 23.8 0.0 8.3e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 PX domain Fungal_trans_2 PF11951.3 KPI43729.1 - 0.00072 18.2 0.2 0.0015 17.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Thioredoxin PF00085.15 KPI43730.1 - 2e-20 72.4 0.1 2.4e-20 72.1 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KPI43730.1 - 8.1e-07 29.0 0.1 0.00016 21.6 0.1 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KPI43730.1 - 3.4e-05 24.0 0.6 0.00031 20.9 0.4 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 KPI43730.1 - 0.00018 21.2 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_7 PF13899.1 KPI43730.1 - 0.00042 20.2 0.0 0.00057 19.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.6 KPI43730.1 - 0.0007 19.4 0.0 0.00085 19.1 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE DUF953 PF06110.6 KPI43730.1 - 0.00077 18.8 0.2 0.0043 16.4 0.1 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) AhpC-TSA PF00578.16 KPI43730.1 - 0.00082 19.0 0.2 0.0027 17.4 0.1 1.6 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 KPI43730.1 - 0.0045 16.5 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 KPI43730.1 - 0.0055 16.2 0.0 0.0065 16.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.19 KPI43730.1 - 0.022 14.7 0.2 0.042 13.8 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin DSBA PF01323.15 KPI43730.1 - 0.023 14.2 0.2 1.1 8.7 0.1 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.1 KPI43730.1 - 0.037 13.5 0.1 1.4 8.4 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin CobU PF02283.11 KPI43730.1 - 0.052 12.9 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Phospholip_A2_3 PF09056.6 KPI43731.1 - 3.8e-33 114.0 0.1 4.5e-33 113.7 0.1 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 RRM_1 PF00076.17 KPI43732.1 - 1.3e-14 53.5 0.0 2.1e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI43732.1 - 1.8e-11 43.8 0.0 3.1e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI43732.1 - 0.00014 21.5 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40_alt PF14077.1 KPI43732.1 - 0.11 12.2 0.4 0.2 11.3 0.2 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif zf-C2H2_2 PF12756.2 KPI43733.1 - 1.4e-22 79.7 11.3 2.9e-22 78.6 7.8 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KPI43733.1 - 5.6 7.5 14.9 5 7.6 0.4 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type PGM_PMM_I PF02878.11 KPI43734.1 - 7.3e-34 116.2 0.0 1.1e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KPI43734.1 - 3.6e-23 81.7 0.0 6.6e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KPI43734.1 - 5.4e-16 58.8 0.0 1.2e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KPI43734.1 - 8.2e-06 25.7 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain AIG2 PF06094.7 KPI43735.1 - 0.0068 16.8 0.0 0.013 15.9 0.0 1.5 1 1 0 1 1 1 1 AIG2-like family Neisseria_TspB PF05616.8 KPI43735.1 - 2.3 6.4 5.3 2.8 6.2 3.7 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein FA_desaturase PF00487.19 KPI43736.1 - 1.6e-18 67.0 14.3 1.6e-18 67.0 9.9 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KPI43736.1 - 3.9e-16 58.5 0.1 1e-15 57.2 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_hydro_72 PF03198.9 KPI43737.1 - 2.8e-81 272.9 0.1 6.4e-81 271.7 0.1 1.5 1 1 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 KPI43737.1 - 0.097 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Sod_Cu PF00080.15 KPI43738.1 - 1e-14 54.8 0.7 1.6e-14 54.2 0.3 1.4 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Mucin PF01456.12 KPI43738.1 - 0.23 11.2 14.1 0.57 9.9 9.8 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Abhydrolase_6 PF12697.2 KPI43739.1 - 3.5e-08 33.6 0.0 6.9e-08 32.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI43739.1 - 0.008 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Tub_2 PF04525.7 KPI43740.1 - 1.9e-08 33.9 0.3 7.8e-08 31.9 0.0 2.5 2 1 0 2 2 2 1 Tubby C 2 PH_6 PF15406.1 KPI43741.1 - 2.4e-29 101.6 3.5 2.4e-29 101.6 2.4 3.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KPI43741.1 - 0.075 13.2 0.0 0.075 13.2 0.0 2.6 2 1 0 2 2 2 0 PH domain PAPS_reduct PF01507.14 KPI43742.1 - 2.8e-42 144.4 0.0 3.8e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Sod_Cu PF00080.15 KPI43742.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.5 1 1 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) FSH1 PF03959.8 KPI43743.1 - 2.7e-54 183.8 0.0 3.4e-52 176.9 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Ribosomal_S27e PF01667.12 KPI43743.1 - 3.9e-27 93.5 6.0 7.2e-27 92.7 4.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S27 Abhydrolase_5 PF12695.2 KPI43743.1 - 1.5e-06 28.0 0.0 2.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI43743.1 - 0.00062 19.7 0.1 0.38 10.6 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family adh_short PF00106.20 KPI43744.1 - 2.5e-20 73.0 0.3 3.2e-20 72.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI43744.1 - 1.1e-16 61.3 0.0 1.5e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI43744.1 - 9.5e-10 38.4 0.1 1.3e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 KR domain RIC1 PF07064.8 KPI43744.1 - 0.056 12.8 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 RIC1 MoaC PF01967.16 KPI43745.1 - 1.7e-34 118.3 0.0 3.4e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 KPI43745.1 - 8.8e-34 115.9 0.0 3.3e-33 114.0 0.0 1.9 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KPI43745.1 - 1.1e-22 80.9 0.1 2e-22 80.1 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KPI43745.1 - 9.2e-07 29.0 0.0 1.9e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KPI43745.1 - 1.1e-05 25.4 0.0 2.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Chitin_synth_2 PF03142.10 KPI43748.1 - 2.3e-217 722.5 0.2 4.2e-216 718.4 0.1 2.0 1 1 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KPI43748.1 - 1.8e-61 208.0 0.0 6.5e-60 202.9 0.0 2.5 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 KPI43748.1 - 3e-19 69.5 4.0 3e-19 69.5 2.8 2.8 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 KPI43748.1 - 1.7e-18 66.1 0.0 6e-12 45.1 0.0 2.6 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 KPI43748.1 - 2.7e-17 63.3 0.0 6.6e-14 52.2 0.0 2.9 3 0 0 3 3 3 2 Glycosyltransferase like family 2 DEK_C PF08766.6 KPI43748.1 - 4.7e-14 51.8 0.1 3.4e-13 49.1 0.0 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_transf_21 PF13506.1 KPI43748.1 - 2.1e-07 30.4 0.0 1.9e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KPI43748.1 - 0.00021 21.0 0.0 0.049 13.3 0.0 3.2 3 0 0 3 3 3 1 Glycosyl transferase family 2 Vps52 PF04129.7 KPI43750.1 - 2.3e-121 405.8 0.0 3.1e-121 405.4 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family HAUS5 PF14817.1 KPI43750.1 - 0.0094 14.5 0.6 0.018 13.6 0.5 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 PilJ PF13675.1 KPI43750.1 - 0.027 14.7 2.1 20 5.5 1.1 3.2 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term SmpA_OmlA PF04355.8 KPI43750.1 - 0.11 12.1 0.3 2.4 7.8 0.1 2.5 2 0 0 2 2 2 0 SmpA / OmlA family THOC7 PF05615.8 KPI43750.1 - 0.16 12.2 2.5 0.5 10.6 1.7 1.9 1 1 0 1 1 1 0 Tho complex subunit 7 Spc7 PF08317.6 KPI43750.1 - 0.22 10.1 4.3 0.38 9.3 3.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.6 KPI43750.1 - 0.41 10.4 4.9 0.78 9.5 3.0 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Cep57_MT_bd PF06657.8 KPI43750.1 - 1.3 9.0 4.7 1.5 8.8 1.0 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 WD40 PF00400.27 KPI43751.1 - 4.8e-22 76.9 2.2 2.5e-05 23.9 0.1 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat DUF1510 PF07423.6 KPI43752.1 - 0.012 14.9 15.3 0.017 14.4 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 KPI43752.1 - 0.2 11.6 19.2 0.3 11.0 13.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Apis_Csd PF11671.3 KPI43752.1 - 0.48 10.2 6.3 0.84 9.4 4.4 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Ycf1 PF05758.7 KPI43752.1 - 0.48 8.0 15.2 0.64 7.6 10.5 1.1 1 0 0 1 1 1 0 Ycf1 FLO_LFY PF01698.11 KPI43752.1 - 0.72 8.6 11.0 1.2 7.9 7.6 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Tim54 PF11711.3 KPI43752.1 - 0.74 8.3 9.1 1.1 7.7 6.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AIF_C PF14721.1 KPI43752.1 - 1.1 9.5 7.7 2.4 8.3 5.3 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term BTV_NS2 PF04514.7 KPI43752.1 - 1.2 7.9 12.2 1.6 7.5 8.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 GAGA_bind PF06217.7 KPI43752.1 - 5.2 6.9 14.2 5.7 6.8 8.9 1.7 2 0 0 2 2 2 0 GAGA binding protein-like family AA_permease PF00324.16 KPI43753.1 - 3.8e-114 381.6 34.2 5.1e-114 381.2 23.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI43753.1 - 3.2e-28 98.4 37.6 4.8e-28 97.8 26.0 1.1 1 0 0 1 1 1 1 Amino acid permease LSM14 PF12701.2 KPI43754.1 - 0.02 14.6 0.0 2.1 8.2 0.0 2.7 3 0 0 3 3 3 0 Scd6-like Sm domain Fungal_trans PF04082.13 KPI43755.1 - 2.1e-15 56.3 0.1 2.9e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Terpene_synth_C PF03936.11 KPI43755.1 - 0.078 12.1 0.2 0.15 11.2 0.1 1.4 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain DUF726 PF05277.7 KPI43756.1 - 1.4e-111 372.7 1.8 1.9e-111 372.2 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.15 KPI43756.1 - 0.052 13.7 4.0 0.096 12.9 0.0 2.5 2 1 0 2 2 2 0 Thioesterase domain Abhydrolase_6 PF12697.2 KPI43756.1 - 0.053 13.3 0.9 0.14 12.0 0.2 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family Fungal_trans PF04082.13 KPI43757.1 - 2e-14 53.1 0.4 3.1e-14 52.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI43757.1 - 5e-08 32.7 10.0 9.3e-08 31.8 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KPI43759.1 - 1.1e-41 139.2 5.7 1.3e-08 34.3 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KPI43759.1 - 2.6e-08 33.4 0.8 6.1e-08 32.2 0.5 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KPI43759.1 - 5.7e-06 24.7 0.2 0.00072 17.8 0.0 3.3 2 1 0 3 3 3 1 Nucleoporin Nup120/160 F-box PF00646.28 KPI43759.1 - 9.8e-06 25.0 0.6 1.9e-05 24.2 0.4 1.5 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.1 KPI43759.1 - 0.14 12.5 0.2 1.1e+02 3.2 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain WD40 PF00400.27 KPI43761.1 - 1.3e-43 145.3 14.8 4.9e-11 42.0 0.1 6.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KPI43761.1 - 1.9e-05 23.6 0.5 0.55 8.9 0.1 3.9 2 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 KPI43761.1 - 2.3e-05 22.7 2.6 0.15 10.2 0.1 3.9 3 1 0 3 3 3 3 Nucleoporin Nup120/160 DUF3312 PF11768.3 KPI43761.1 - 0.11 10.7 0.0 0.16 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) PUF PF00806.14 KPI43762.1 - 7.9e-27 91.1 0.0 0.00015 21.0 0.0 6.5 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 KPI43762.1 - 2e-10 40.1 0.0 4e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI43762.1 - 2.2e-06 27.5 0.0 4.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI43762.1 - 6.5e-06 25.8 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2361 PF10153.4 KPI43763.1 - 4.9e-21 75.0 1.7 9e-21 74.1 1.2 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2361) Polysacc_deac_1 PF01522.16 KPI43764.1 - 1.2e-20 73.4 0.0 2.1e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2194 PF09960.4 KPI43764.1 - 0.037 12.0 0.0 0.057 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) Methyltransf_23 PF13489.1 KPI43765.1 - 4.7e-17 62.1 0.0 5.9e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI43765.1 - 4.1e-16 59.2 0.0 3.2e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI43765.1 - 8.4e-14 52.1 0.0 2e-13 50.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI43765.1 - 2.9e-12 46.4 0.0 4.2e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI43765.1 - 8.4e-12 45.4 0.0 1.4e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI43765.1 - 1.2e-11 44.8 0.0 3.1e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI43765.1 - 7.9e-10 38.7 0.1 1.5e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KPI43765.1 - 5.5e-09 35.4 0.0 6.7e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KPI43765.1 - 3.2e-07 29.8 0.0 4.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KPI43765.1 - 1.7e-05 24.1 0.0 2.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 KPI43765.1 - 0.0012 17.6 0.0 0.0016 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.9 KPI43765.1 - 0.0017 17.5 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Pox_MCEL PF03291.11 KPI43765.1 - 0.0043 15.9 0.0 0.028 13.2 0.0 2.0 1 1 0 1 1 1 1 mRNA capping enzyme POR PF01558.13 KPI43765.1 - 0.0093 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase CheR PF01739.13 KPI43765.1 - 0.012 14.8 0.0 2.2 7.5 0.0 2.4 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain NAD_binding_10 PF13460.1 KPI43765.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding UPF0146 PF03686.8 KPI43765.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) TPMT PF05724.6 KPI43765.1 - 0.014 14.8 0.0 0.056 12.8 0.0 1.9 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) NNMT_PNMT_TEMT PF01234.12 KPI43765.1 - 0.039 12.9 0.0 0.47 9.3 0.0 2.1 1 1 0 2 2 2 0 NNMT/PNMT/TEMT family UDPG_MGDP_dh_N PF03721.9 KPI43765.1 - 0.039 13.3 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PCMT PF01135.14 KPI43765.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AdoMet_MTase PF07757.8 KPI43765.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Ribosomal_L1 PF00687.16 KPI43766.1 - 5.9e-47 159.8 1.1 2.7e-46 157.6 0.8 1.7 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family COesterase PF00135.23 KPI43767.1 - 7e-66 223.0 0.0 3.6e-64 217.3 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI43767.1 - 4e-06 26.5 0.3 0.018 14.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF605 PF04652.11 KPI43768.1 - 0.47 9.8 14.0 0.54 9.5 9.7 1.2 1 0 0 1 1 1 0 Vta1 like DAO PF01266.19 KPI43769.1 - 1.7e-29 102.8 2.4 1.9e-29 102.6 1.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI43769.1 - 0.0003 19.7 2.0 0.00044 19.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KPI43769.1 - 0.00049 20.0 0.8 0.0021 18.0 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI43769.1 - 0.02 14.7 0.0 0.02 14.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI43769.1 - 0.029 13.4 0.0 0.029 13.4 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.1 KPI43769.1 - 0.037 14.0 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KPI43769.1 - 0.038 13.0 0.1 0.065 12.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 KPI43769.1 - 0.1 11.1 0.2 0.57 8.7 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.22 KPI43769.1 - 0.12 12.8 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI43769.1 - 0.14 10.6 1.0 0.18 10.2 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein PhyH PF05721.8 KPI43770.1 - 2.2e-20 73.6 0.1 2.9e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 KPI43770.1 - 0.082 13.2 0.0 0.43 10.8 0.0 2.1 1 1 1 2 2 2 0 Putative 2OG-Fe(II) oxygenase Abhydrolase_6 PF12697.2 KPI43771.1 - 6e-16 59.0 0.1 1.1e-15 58.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI43771.1 - 1.9e-08 34.1 0.1 4.1e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI43771.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI43771.1 - 0.031 13.5 0.0 6.5 5.9 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family TRI12 PF06609.8 KPI43772.1 - 1.3e-23 83.1 29.4 2.2e-23 82.3 20.4 1.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI43772.1 - 2e-16 59.6 61.3 5e-16 58.3 39.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily UPF0075 PF03702.9 KPI43773.1 - 2e-09 36.8 0.0 2.2e-09 36.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) Glyco_hydro_65m PF03632.10 KPI43775.1 - 2.3e-74 250.3 3.3 2.2e-73 247.1 2.3 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 KPI43775.1 - 1.5e-38 132.5 0.0 2.6e-38 131.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 KPI43775.1 - 0.00088 19.3 0.4 0.0022 18.0 0.3 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain LigB PF02900.13 KPI43776.1 - 7.3e-22 77.6 0.1 1.1e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Glyco_hydro_16 PF00722.16 KPI43777.1 - 6.5e-06 25.5 0.0 1.7e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 GRP PF07172.6 KPI43777.1 - 1.2 9.6 13.9 0.46 10.9 4.3 2.4 2 0 0 2 2 2 0 Glycine rich protein family Acyl-CoA_dh_1 PF00441.19 KPI43779.1 - 1.5e-16 60.8 0.0 3e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KPI43779.1 - 4.4e-07 29.3 0.0 0.0041 16.6 0.0 2.7 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, middle domain Cpn60_TCP1 PF00118.19 KPI43780.1 - 7.1e-150 499.8 0.5 8.1e-150 499.6 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Methyltransf_2 PF00891.13 KPI43781.1 - 1.6e-21 76.6 0.0 2.8e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase GatB_Yqey PF02637.13 KPI43781.1 - 0.32 10.7 2.4 5.8 6.6 0.6 2.5 1 1 1 2 2 2 0 GatB domain FMO-like PF00743.14 KPI43782.1 - 3.9e-15 55.0 0.1 1.2e-13 50.1 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KPI43782.1 - 5.6e-15 55.9 0.0 2.4e-14 53.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI43782.1 - 4.5e-08 33.0 1.2 7.3e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KPI43782.1 - 1.7e-05 23.9 0.1 0.00011 21.2 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KPI43782.1 - 0.12 12.1 0.9 1.3 8.7 0.0 2.8 4 0 0 4 4 4 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KPI43783.1 - 2.1e-43 148.7 0.0 2.6e-42 145.1 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain CHORD PF04968.7 KPI43784.1 - 1.1e-43 147.3 16.8 4.5e-24 84.4 5.9 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 KPI43784.1 - 5.7e-10 39.6 0.1 9.6e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 CS domain Sugar_tr PF00083.19 KPI43785.1 - 2.1e-80 270.5 18.1 2.6e-80 270.2 12.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI43785.1 - 7.3e-09 34.8 40.4 8.8e-06 24.6 8.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily zf-H2C2_2 PF13465.1 KPI43786.1 - 4.2e-07 29.9 5.8 3.4e-06 27.0 0.4 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KPI43786.1 - 3.3e-05 23.9 9.0 4.4e-05 23.5 0.2 3.6 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI43786.1 - 5.5e-05 23.2 5.2 0.0021 18.2 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KPI43786.1 - 0.036 14.2 0.4 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KPI43786.1 - 0.094 12.9 0.5 13 6.1 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type adh_short PF00106.20 KPI43787.1 - 3.6e-28 98.5 0.1 4.8e-28 98.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI43787.1 - 2.2e-25 89.8 0.0 2.6e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI43787.1 - 4.9e-12 45.8 0.0 6.9e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI43787.1 - 0.0002 20.9 0.0 0.00026 20.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KPI43787.1 - 0.006 16.3 0.5 0.015 15.1 0.3 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AdoHcyase_NAD PF00670.16 KPI43787.1 - 0.0066 16.3 0.7 0.012 15.5 0.5 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3Beta_HSD PF01073.14 KPI43787.1 - 0.0078 14.9 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 KPI43787.1 - 0.0093 15.0 0.1 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 KPI43787.1 - 0.024 14.7 0.0 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KPI43787.1 - 0.044 12.6 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.1 KPI43787.1 - 0.049 13.8 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 KPI43787.1 - 0.083 12.5 0.1 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KPI43787.1 - 0.15 11.2 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.3 KPI43788.1 - 4.8e-17 61.6 0.8 2.3e-15 56.1 0.4 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI43788.1 - 0.001 18.9 5.6 0.0017 18.2 3.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KPI43788.1 - 0.11 11.3 0.5 0.28 10.0 0.3 1.5 1 1 0 1 1 1 0 Fungal specific transcription factor domain RIC1 PF07064.8 KPI43789.1 - 1.3e-33 116.5 0.2 1.9e-33 116.0 0.1 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 KPI43789.1 - 0.023 14.5 3.1 3.3 7.7 0.0 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat Fungal_trans_2 PF11951.3 KPI43790.1 - 1.6e-20 73.1 6.9 1.9e-19 69.5 4.8 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain N2227 PF07942.7 KPI43791.1 - 7.5e-35 120.1 0.0 1.2e-34 119.5 0.0 1.3 1 1 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KPI43791.1 - 0.0061 16.2 0.0 0.0076 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Fungal_trans PF04082.13 KPI43792.1 - 1.3e-25 89.7 0.1 2.8e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mnd1 PF03962.10 KPI43792.1 - 0.13 11.8 1.0 2 8.0 0.0 2.2 2 0 0 2 2 2 0 Mnd1 family GMC_oxred_N PF00732.14 KPI43793.1 - 4.9e-51 173.6 0.0 6.9e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI43793.1 - 9.6e-34 116.7 0.0 1.8e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KPI43793.1 - 3.4e-05 22.8 0.0 0.18 10.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KPI43793.1 - 5.9e-05 23.0 0.1 0.00017 21.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KPI43793.1 - 0.00011 21.3 0.0 0.00019 20.4 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KPI43793.1 - 0.00018 20.5 0.2 0.00046 19.1 0.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI43793.1 - 0.013 15.3 0.0 0.055 13.3 0.0 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KPI43793.1 - 0.028 13.0 0.0 0.041 12.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Mit_ribos_Mrp51 PF11709.3 KPI43794.1 - 6.7e-55 186.5 0.1 1.5e-51 175.4 0.1 2.4 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.13 KPI43795.1 - 1.9e-58 195.5 0.5 2.4e-58 195.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 KPI43795.1 - 0.001 19.7 0.2 0.0015 19.2 0.1 1.2 1 0 0 1 1 1 1 Blue/Ultraviolet sensing protein C terminal Cyclin_N PF00134.18 KPI43796.1 - 3.4e-14 52.5 0.2 5.6e-14 51.8 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KPI43796.1 - 0.0002 21.2 0.1 0.14 12.1 0.0 2.5 2 0 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.14 KPI43796.1 - 0.012 15.4 0.4 1 9.1 0.2 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Totivirus_coat PF05518.6 KPI43796.1 - 7.1 4.3 11.2 12 3.6 7.7 1.3 1 0 0 1 1 1 0 Totivirus coat protein Zn_clus PF00172.13 KPI43797.1 - 0.022 14.6 9.3 0.047 13.5 6.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RP-C_C PF11800.3 KPI43798.1 - 0.061 13.0 0.2 0.097 12.3 0.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region V-SNARE_C PF12352.3 KPI43799.1 - 8.4e-15 54.6 0.2 8.4e-15 54.6 0.1 2.7 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus AAA_13 PF13166.1 KPI43799.1 - 0.0054 15.2 3.9 0.0065 15.0 2.7 1.1 1 0 0 1 1 1 1 AAA domain Surfac_D-trimer PF09006.6 KPI43799.1 - 0.0085 15.7 0.1 0.024 14.3 0.0 1.8 1 0 0 1 1 1 1 Lung surfactant protein D coiled-coil trimerisation Syntaxin-6_N PF09177.6 KPI43799.1 - 0.086 13.2 9.0 0.14 12.5 4.6 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF1822 PF08852.6 KPI43799.1 - 0.12 11.2 4.3 0.15 10.8 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) SAB PF04382.8 KPI43799.1 - 0.44 10.2 5.1 3.5 7.3 0.6 2.5 2 0 0 2 2 2 0 SAB domain Syntaxin_2 PF14523.1 KPI43799.1 - 1 9.4 10.2 5.8 7.0 4.4 2.9 1 1 1 2 2 2 0 Syntaxin-like protein TBPIP PF07106.8 KPI43799.1 - 1 8.8 9.5 2.1 7.8 5.3 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) STAT_alpha PF01017.15 KPI43799.1 - 1.1 8.9 7.0 2.3 7.8 4.1 2.0 1 1 2 3 3 3 0 STAT protein, all-alpha domain IncA PF04156.9 KPI43799.1 - 7.6 6.0 19.0 9.8 5.7 12.3 1.8 1 1 0 1 1 1 0 IncA protein DAHP_synth_1 PF00793.15 KPI43800.1 - 1.3e-83 279.8 0.0 1.6e-83 279.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2313 PF10076.4 KPI43800.1 - 0.027 13.8 0.2 0.077 12.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2313) Paramyxo_NS_C PF02725.9 KPI43800.1 - 0.13 11.8 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Non-structural protein C Fungal_trans PF04082.13 KPI43801.1 - 3.4e-17 62.1 0.7 4e-11 42.2 0.0 2.8 2 1 1 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI43801.1 - 3e-06 27.0 8.1 4.7e-06 26.4 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S15 PF02129.13 KPI43802.1 - 2.8e-39 135.1 0.3 4.2e-39 134.6 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KPI43802.1 - 7e-37 127.4 0.5 1e-36 126.8 0.3 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KPI43802.1 - 0.00079 19.3 0.5 0.0024 17.8 0.2 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI43802.1 - 0.0011 18.7 0.0 0.0043 16.8 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF3984 PF13136.1 KPI43803.1 - 9.7e-49 166.3 0.7 1.8e-48 165.4 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) EPL1 PF10513.4 KPI43803.1 - 0.012 15.8 0.1 0.068 13.4 0.0 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Ecm33 PF12454.3 KPI43804.1 - 2.6e-06 27.1 0.5 2.6e-06 27.1 0.3 2.2 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 KPI43804.1 - 3.5e-06 26.9 2.7 0.045 13.7 0.0 3.6 2 1 1 3 3 3 3 Receptor L domain LRR_5 PF13306.1 KPI43804.1 - 0.048 13.3 0.9 0.23 11.1 0.2 2.3 1 1 1 2 2 2 0 Leucine rich repeats (6 copies) MAGE PF01454.14 KPI43805.1 - 4.7e-38 130.4 0.0 6.1e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 MAGE family BTB PF00651.26 KPI43806.1 - 3.4e-12 46.3 0.2 3e-11 43.2 0.2 2.2 1 1 0 1 1 1 1 BTB/POZ domain Fib_alpha PF08702.5 KPI43807.1 - 0.1 12.7 14.0 0.55 10.3 4.9 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Sec8_exocyst PF04048.9 KPI43807.1 - 0.68 9.5 6.4 2.6 7.6 0.1 3.2 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Kinetocho_Slk19 PF12709.2 KPI43807.1 - 0.68 10.0 24.7 5.2 7.2 0.4 4.7 2 1 2 4 4 4 0 Central kinetochore-associated CENP-F_leu_zip PF10473.4 KPI43807.1 - 1.8 8.4 23.7 0.17 11.7 12.4 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IFT57 PF10498.4 KPI43807.1 - 1.9 7.1 12.4 3 6.5 8.1 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2951 PF11166.3 KPI43807.1 - 2.6 7.9 5.9 1.3 8.9 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) Trep_dent_lipo PF09710.5 KPI43807.1 - 3.4 6.2 7.7 0.057 12.0 0.5 1.5 2 0 0 2 2 2 0 Treponema clustered lipoprotein (Trep_dent_lipo) DUF87 PF01935.12 KPI43807.1 - 6.7 6.4 7.1 2.7 7.7 3.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 FKBP_N PF01346.13 KPI43807.1 - 9.4 6.3 13.3 5.8 6.9 6.8 2.4 1 1 2 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase YEATS PF03366.11 KPI43808.1 - 1.6e-10 40.5 1.1 3.2e-10 39.5 0.8 1.6 1 1 0 1 1 1 1 YEATS family zf-RING_2 PF13639.1 KPI43808.1 - 3.5e-08 33.1 4.8 6e-08 32.4 3.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KPI43808.1 - 7.3e-08 32.1 2.5 7.3e-08 32.1 1.8 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KPI43808.1 - 7.3e-08 32.3 4.3 2.2e-07 30.7 3.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KPI43808.1 - 7.6e-07 28.7 4.0 1.4e-06 27.8 2.8 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI43808.1 - 5.8e-06 25.8 5.9 2.6e-05 23.8 4.1 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KPI43808.1 - 3.3e-05 23.4 2.3 3.3e-05 23.4 1.6 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 KPI43808.1 - 0.0021 17.7 8.4 0.0086 15.7 6.1 1.9 1 1 1 2 2 2 1 zinc-RING finger domain GAGA PF09237.6 KPI43808.1 - 0.021 14.4 2.5 0.54 9.9 0.1 2.5 2 0 0 2 2 2 0 GAGA factor P_proprotein PF01483.15 KPI43808.1 - 0.31 10.8 2.3 0.31 10.8 0.4 1.9 2 0 0 2 2 2 0 Proprotein convertase P-domain zf-MIZ PF02891.15 KPI43808.1 - 0.83 9.2 7.4 0.27 10.7 1.6 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Prok-RING_4 PF14447.1 KPI43808.1 - 1 8.9 8.6 15 5.2 0.1 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Acyl-CoA_dh_1 PF00441.19 KPI43809.1 - 4e-21 75.6 0.9 7.7e-21 74.7 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KPI43809.1 - 1.5e-20 72.4 0.5 2.6e-20 71.6 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KPI43809.1 - 6.4e-14 52.4 1.6 3.5e-13 50.1 0.0 2.8 2 2 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KPI43809.1 - 3.1e-05 24.2 0.3 5.3e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Methyltransf_8 PF05148.10 KPI43810.1 - 8.7e-57 192.2 0.0 2.8e-54 184.0 0.0 2.9 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KPI43810.1 - 7.5e-05 23.1 0.0 0.00023 21.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI43810.1 - 0.011 16.1 0.0 0.25 11.7 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 KPI43810.1 - 0.018 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 KPI43810.1 - 0.16 10.9 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) UBA_4 PF14555.1 KPI43811.1 - 0.87 9.1 6.0 0.11 12.0 0.2 2.4 3 0 0 3 3 3 0 UBA-like domain GST_C_3 PF14497.1 KPI43812.1 - 1.4e-11 44.7 0.0 2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KPI43812.1 - 9.6e-09 35.1 0.0 1.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI43812.1 - 2.2e-05 24.2 0.0 4.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KPI43812.1 - 0.012 15.7 0.1 0.35 11.0 0.0 2.5 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain A-2_8-polyST PF07388.6 KPI43812.1 - 0.12 10.7 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Alpha-2,8-polysialyltransferase (POLYST) DUF2235 PF09994.4 KPI43813.1 - 3.5e-63 213.5 0.0 1.3e-62 211.7 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) ACBP PF00887.14 KPI43815.1 - 6.7e-19 67.3 1.7 7.6e-18 63.9 1.2 1.9 1 1 0 1 1 1 1 Acyl CoA binding protein COesterase PF00135.23 KPI43816.1 - 2e-100 337.0 0.0 2.6e-100 336.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI43816.1 - 6.9e-05 22.5 0.0 0.00015 21.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI43816.1 - 0.022 13.9 0.2 0.041 13.1 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Na_Ca_ex PF01699.19 KPI43817.1 - 1.8e-10 40.5 6.7 1.8e-10 40.5 4.7 2.3 3 0 0 3 3 3 1 Sodium/calcium exchanger protein RhodobacterPufX PF11511.3 KPI43817.1 - 0.17 11.2 0.4 4.8 6.6 0.0 2.7 2 0 0 2 2 2 0 Intrinsic membrane protein PufX Kinetocho_Slk19 PF12709.2 KPI43818.1 - 1.4e-15 57.0 3.4 1.4e-15 57.0 2.4 4.4 3 1 3 6 6 6 2 Central kinetochore-associated IncA PF04156.9 KPI43818.1 - 0.0008 19.0 5.7 0.0008 19.0 4.0 2.4 2 0 0 2 2 2 1 IncA protein CENP-F_leu_zip PF10473.4 KPI43818.1 - 0.01 15.6 6.1 0.01 15.6 4.2 4.2 3 2 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF496 PF04363.7 KPI43818.1 - 0.03 14.1 2.9 0.097 12.5 2.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF496) AHS1 PF02682.11 KPI43818.1 - 0.14 11.5 0.1 0.14 11.5 0.0 2.4 2 1 1 3 3 3 0 Allophanate hydrolase subunit 1 ERM PF00769.14 KPI43818.1 - 0.18 11.2 41.6 0.52 9.8 15.8 3.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF724 PF05266.9 KPI43818.1 - 3.1 7.3 24.9 0.42 10.2 3.7 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF724) LXG PF04740.7 KPI43818.1 - 3.3 7.4 11.5 0.36 10.5 1.8 2.8 2 1 1 3 3 3 0 LXG domain of WXG superfamily Myosin_tail_1 PF01576.14 KPI43818.1 - 4 5.0 47.8 57 1.2 33.2 2.5 1 1 0 1 1 1 0 Myosin tail Nramp PF01566.13 KPI43819.1 - 6.5e-74 248.8 11.6 1.3e-66 224.7 6.6 2.3 1 1 1 2 2 2 2 Natural resistance-associated macrophage protein DUF1746 PF08508.5 KPI43819.1 - 0.15 12.0 3.8 1.8 8.5 0.1 2.5 1 1 1 2 2 2 0 Fungal domain of unknown function (DUF1746) Ribosomal_S21 PF01165.15 KPI43820.1 - 6.4e-09 35.1 4.0 6.4e-09 35.1 2.8 1.4 2 0 0 2 2 2 1 Ribosomal protein S21 Abhydrolase_6 PF12697.2 KPI43821.1 - 1.7e-21 77.1 0.0 2.5e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI43821.1 - 8.6e-11 41.8 0.0 1.1e-09 38.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI43821.1 - 0.012 14.8 0.0 2.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Aminotran_4 PF01063.14 KPI43822.1 - 2.7e-25 89.2 0.0 3.5e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV DLL_N PF12413.3 KPI43823.1 - 0.63 11.1 0.1 0.63 11.1 0.1 2.2 2 0 0 2 2 2 0 Homeobox protein distal-less-like N terminal Complex1_LYR_1 PF13232.1 KPI43825.1 - 1.2e-19 70.2 1.6 1.6e-19 69.8 1.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KPI43825.1 - 1.2e-18 66.6 1.6 1.6e-18 66.2 1.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KPI43825.1 - 0.062 13.7 0.3 0.08 13.4 0.2 1.2 1 0 0 1 1 1 0 Complex1_LYR-like SSFA2_C PF14723.1 KPI43825.1 - 0.096 12.4 0.1 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus ALS2CR8 PF15299.1 KPI43825.1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 OPT PF03169.10 KPI43826.1 - 9.6e-117 390.9 5.0 1.2e-116 390.6 3.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FERM_M PF00373.13 KPI43826.1 - 0.028 14.5 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 FERM central domain Sugar_tr PF00083.19 KPI43827.1 - 5.9e-11 41.6 0.3 6.5e-11 41.4 0.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter VirB3 PF05101.8 KPI43827.1 - 1.6 8.7 4.0 1.1 9.3 0.0 2.4 2 1 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein RNase_T PF00929.19 KPI43828.1 - 0.023 14.9 0.0 0.036 14.3 0.0 1.3 1 0 0 1 1 1 0 Exonuclease Thiolase_C PF02803.13 KPI43829.1 - 1.4e-12 47.0 1.2 1.8e-12 46.7 0.1 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KPI43829.1 - 2.1e-05 24.0 0.2 4.4e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KPI43829.1 - 0.001 18.6 0.1 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 KPI43829.1 - 0.0028 16.6 0.0 0.0055 15.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain SpoVAD PF07451.6 KPI43829.1 - 0.033 12.6 0.1 0.055 11.9 0.1 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Pyr_redox_3 PF13738.1 KPI43830.1 - 3e-20 73.1 0.0 4.1e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI43830.1 - 1.6e-06 26.6 0.0 2.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI43830.1 - 0.00058 19.8 0.6 0.0021 18.0 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KPI43830.1 - 0.016 14.9 0.0 4.2 7.1 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KPI43830.1 - 0.018 14.9 0.2 6.6 6.5 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase tRNA_int_endo PF01974.12 KPI43830.1 - 0.065 13.0 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, catalytic C-terminal domain ADH_zinc_N PF00107.21 KPI43831.1 - 4.8e-13 48.7 0.0 9e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI43831.1 - 2e-07 30.7 0.9 6.5e-07 29.0 0.5 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Inhibitor_I78 PF11720.3 KPI43832.1 - 2e-09 37.0 0.0 2.6e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 KPI43832.1 - 0.0065 16.5 0.0 0.0091 16.1 0.0 1.2 1 0 0 1 1 1 1 Potato inhibitor I family Fork_head PF00250.13 KPI43833.1 - 1.7e-11 43.9 4.3 3.9e-11 42.8 0.6 2.3 1 1 1 2 2 2 1 Fork head domain FHA PF00498.21 KPI43833.1 - 8.4e-07 29.0 0.0 1.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain ATP-synt_F PF01990.12 KPI43835.1 - 1.7e-32 111.6 0.1 1.9e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF202 PF02656.10 KPI43836.1 - 4.7e-10 39.5 0.7 6.4e-10 39.1 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Rhodanese PF00581.15 KPI43837.1 - 2.8e-11 43.7 0.0 1.4e-08 35.0 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Cid2 PF09774.4 KPI43838.1 - 1e-40 139.2 0.0 1.3e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 MmgE_PrpD PF03972.9 KPI43839.1 - 1.5e-30 105.7 3.7 2.1e-30 105.3 2.6 1.1 1 0 0 1 1 1 1 MmgE/PrpD family DUF1775 PF07987.6 KPI43839.1 - 0.046 13.5 0.2 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unkown function (DUF1775) MFS_1 PF07690.11 KPI43840.1 - 7.1e-51 172.9 21.8 7.1e-51 172.9 15.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI43840.1 - 2.4e-12 46.1 5.7 2.4e-12 46.1 3.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 KPI43840.1 - 1.6 6.6 11.3 0.038 12.0 0.9 2.8 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Adeno_E3_CR2 PF02439.10 KPI43841.1 - 0.0046 16.4 0.1 0.0084 15.6 0.1 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Pkinase PF00069.20 KPI43842.1 - 5.4e-07 29.0 0.0 1.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI43842.1 - 0.0046 16.0 0.1 0.0073 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.11 KPI43844.1 - 6.4e-26 90.9 34.2 6.4e-26 90.9 23.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KPI43844.1 - 0.036 12.1 0.4 2.8 5.8 0.0 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SNF2_N PF00176.18 KPI43846.1 - 3e-72 242.9 2.1 3e-72 242.9 1.5 2.3 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KPI43846.1 - 2.8e-15 55.9 0.0 7.7e-15 54.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KPI43846.1 - 7.6e-08 32.0 0.0 1.5e-06 27.8 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 KPI43846.1 - 0.026 13.9 0.7 0.059 12.7 0.0 1.9 2 0 0 2 2 2 0 DEAD_2 Apc4 PF12896.2 KPI43848.1 - 2e-49 167.7 0.3 2.9e-49 167.2 0.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 DUF4062 PF13271.1 KPI43848.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) DUF957 PF06117.6 KPI43848.1 - 0.059 12.9 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) TFIID_20kDa PF03847.8 KPI43850.1 - 2.5e-18 66.1 0.0 4.1e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2935 PF11155.3 KPI43850.1 - 1.5 8.9 8.3 0.83 9.7 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) IncA PF04156.9 KPI43850.1 - 2.6 7.5 13.6 0.048 13.2 0.6 2.7 2 0 0 2 2 2 0 IncA protein FAM196 PF15265.1 KPI43850.1 - 3.1 6.9 37.6 4.2 6.4 26.0 1.1 1 0 0 1 1 1 0 FAM196 family CorA PF01544.13 KPI43850.1 - 7.4 5.5 5.8 4.6 6.1 2.3 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Herpes_US9 PF06072.6 KPI43851.1 - 0.003 17.3 0.4 0.006 16.3 0.3 1.5 1 0 0 1 1 1 1 Alphaherpesvirus tegument protein US9 DUF4519 PF15012.1 KPI43851.1 - 0.26 11.2 0.2 0.48 10.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DUF3169 PF11368.3 KPI43851.1 - 0.32 10.1 0.3 0.48 9.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF1628 PF07790.6 KPI43851.1 - 0.76 10.5 5.8 0.4 11.4 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) ATP-sulfurylase PF01747.12 KPI43853.1 - 9.1e-87 289.8 0.0 1.3e-86 289.4 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KPI43853.1 - 8e-55 184.7 0.1 1.3e-54 184.1 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 KPI43853.1 - 5e-50 169.0 0.0 8.1e-50 168.3 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain TOBE PF03459.12 KPI43853.1 - 0.059 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 TOBE domain Surp PF01805.15 KPI43854.1 - 5.9e-19 67.4 0.0 1.2e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Surp module RRM_6 PF14259.1 KPI43854.1 - 0.051 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ebola_NP PF05505.7 KPI43854.1 - 2 6.3 9.2 4.1 5.3 6.4 1.4 1 0 0 1 1 1 0 Ebola nucleoprotein DUF3767 PF12597.3 KPI43855.1 - 1.9e-19 69.4 0.3 2.7e-19 68.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF3493 PF11998.3 KPI43855.1 - 0.049 13.5 0.5 0.094 12.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3493) FAM165 PF14981.1 KPI43855.1 - 0.053 13.0 1.5 0.053 13.0 1.0 1.7 1 1 0 1 1 1 0 FAM165 family 5TM-5TMR_LYT PF07694.7 KPI43855.1 - 0.2 10.9 2.6 0.27 10.5 1.8 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT HET PF06985.6 KPI43856.1 - 1.2e-26 93.5 0.5 2.4e-26 92.5 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Pro-rich_19 PF15455.1 KPI43856.1 - 0.17 10.8 1.9 0.3 10.0 1.3 1.2 1 0 0 1 1 1 0 Proline-rich 19 Ferritin_2 PF13668.1 KPI43857.1 - 6.3e-20 71.5 0.1 1.5e-19 70.3 0.0 1.6 2 0 0 2 2 2 1 Ferritin-like domain Ras PF00071.17 KPI43858.1 - 1.7e-36 125.0 0.0 5.5e-36 123.4 0.0 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KPI43858.1 - 1.2e-18 67.7 0.0 1.7e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KPI43858.1 - 5.2e-12 45.3 0.0 8.7e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KPI43858.1 - 4.3e-06 26.0 0.0 5.7e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 KPI43858.1 - 9e-06 25.7 0.0 0.00012 22.1 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 KPI43858.1 - 5.5e-05 23.1 0.0 0.00013 21.8 0.0 1.7 2 0 0 2 2 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KPI43858.1 - 0.0011 18.2 0.1 0.0024 17.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KPI43858.1 - 0.0063 16.6 0.0 0.044 13.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 KPI43858.1 - 0.019 13.8 0.1 0.08 11.8 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF815) Dynamin_N PF00350.18 KPI43858.1 - 0.026 14.3 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Dynamin family NACHT PF05729.7 KPI43858.1 - 0.054 13.1 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Ribosomal_S21 PF01165.15 KPI43858.1 - 0.055 12.9 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S21 AAA_33 PF13671.1 KPI43858.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KPI43858.1 - 0.072 13.3 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 KPI43858.1 - 0.17 11.3 0.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_10 PF05176.9 KPI43861.1 - 8.1e-63 212.0 0.0 1.1e-62 211.5 0.0 1.2 1 0 0 1 1 1 1 ATP10 protein F-box-like PF12937.2 KPI43862.1 - 1.8e-05 24.3 0.1 8.2e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 F-box-like Zn_clus PF00172.13 KPI43863.1 - 9.8e-07 28.5 6.3 1.9e-06 27.6 4.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HD PF01966.17 KPI43864.1 - 1.2e-06 28.5 0.0 1.6e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 HD domain Lactamase_B PF00753.22 KPI43865.1 - 2.5e-18 66.4 1.5 3.6e-18 65.9 1.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI43865.1 - 2.3e-07 30.5 0.4 3.4e-07 30.0 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain bZIP_1 PF00170.16 KPI43866.1 - 8.9e-11 41.5 10.6 2e-10 40.4 7.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KPI43866.1 - 4e-05 23.3 9.9 4e-05 23.3 6.8 2.6 2 1 0 2 2 2 1 Basic region leucine zipper DUF904 PF06005.7 KPI43866.1 - 0.0048 17.1 1.3 0.0048 17.1 0.9 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF904) Chibby PF14645.1 KPI43866.1 - 0.024 14.5 0.5 0.024 14.5 0.4 2.2 3 0 0 3 3 3 0 Chibby family PilO PF04350.8 KPI43866.1 - 0.027 14.3 0.9 0.027 14.3 0.6 2.4 2 0 0 2 2 2 0 Pilus assembly protein, PilO His_Phos_2 PF00328.17 KPI43867.1 - 6.7e-24 84.8 0.0 8.8e-23 81.1 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF2076 PF09849.4 KPI43867.1 - 0.16 12.0 1.6 0.25 11.3 1.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MFS_1 PF07690.11 KPI43868.1 - 1.1e-33 116.4 28.6 1.1e-33 116.4 19.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF485 PF04341.7 KPI43868.1 - 0.00067 19.3 0.6 0.0034 17.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF485 PGPGW PF09656.5 KPI43868.1 - 2.2 7.6 8.7 2.3 7.6 1.6 3.0 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) 2-Hacid_dh_C PF02826.14 KPI43869.1 - 2.2e-39 134.4 0.0 3.8e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KPI43869.1 - 2.7e-12 46.2 0.0 4.3e-12 45.6 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Saccharop_dh PF03435.13 KPI43869.1 - 0.0015 17.6 1.9 0.072 12.0 0.1 2.3 2 0 0 2 2 2 2 Saccharopine dehydrogenase F420_oxidored PF03807.12 KPI43869.1 - 0.0048 17.3 1.1 0.1 13.0 0.1 2.8 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent HSP70 PF00012.15 KPI43870.1 - 1.5e-11 42.9 0.5 7.6e-10 37.3 0.1 2.1 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 KPI43870.1 - 0.0038 16.8 0.1 0.0097 15.5 0.1 1.6 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 KPI43870.1 - 0.054 12.0 0.1 0.22 10.0 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein StbA PF06406.6 KPI43870.1 - 0.13 11.1 0.2 9 5.1 0.0 2.1 2 0 0 2 2 2 0 StbA protein Herpes_BMRF2 PF04633.7 KPI43873.1 - 0.0039 16.2 0.3 0.0047 15.9 0.2 1.0 1 0 0 1 1 1 1 Herpesvirus BMRF2 protein Mucin PF01456.12 KPI43873.1 - 0.02 14.6 0.4 0.034 13.9 0.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Proteasome PF00227.21 KPI43874.1 - 7.6e-56 188.4 0.0 9.7e-56 188.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KPI43874.1 - 1e-13 50.3 0.2 2.3e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FAA_hydrolase PF01557.13 KPI43875.1 - 5e-61 205.9 0.0 6.4e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Amidase PF01425.16 KPI43877.1 - 5.5e-84 282.5 0.0 6.5e-84 282.3 0.0 1.0 1 0 0 1 1 1 1 Amidase HIT PF01230.18 KPI43880.1 - 1.9e-24 86.0 0.8 3e-24 85.3 0.5 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KPI43880.1 - 4.5e-05 23.6 0.3 6.6e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KPI43880.1 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.12 KPI43880.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain PLDc_2 PF13091.1 KPI43881.1 - 4.1e-23 81.4 0.1 1.7e-13 50.3 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KPI43881.1 - 0.00019 21.1 0.1 0.12 12.2 0.0 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 KPI43881.1 - 0.0038 16.2 0.1 0.25 10.2 0.0 2.3 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB MFS_1 PF07690.11 KPI43882.1 - 5e-25 87.9 57.6 3.4e-20 72.0 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Asn_synthase PF00733.16 KPI43883.1 - 5.8e-31 107.8 0.1 7.1e-31 107.6 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase SLD3 PF08639.5 KPI43884.1 - 2.8e-85 286.8 16.8 4.7e-85 286.1 11.6 1.4 1 0 0 1 1 1 1 DNA replication regulator SLD3 adh_short PF00106.20 KPI43885.1 - 2.2e-14 53.7 0.6 3.1e-14 53.2 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI43885.1 - 6.8e-08 32.3 0.3 2.5e-07 30.5 0.1 1.8 1 1 1 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 KPI43885.1 - 0.00069 19.3 0.2 0.0017 18.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KPI43885.1 - 0.0047 16.3 0.4 0.01 15.2 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KPI43885.1 - 0.0063 15.4 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.1 KPI43885.1 - 0.027 14.7 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF1955 PF09205.5 KPI43885.1 - 0.043 13.3 0.1 0.073 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) EXOSC1 PF10447.4 KPI43887.1 - 0.0044 16.9 0.0 0.99 9.4 0.0 3.1 3 0 0 3 3 3 2 Exosome component EXOSC1/CSL4 Fungal_trans PF04082.13 KPI43888.1 - 6.9e-26 90.6 1.2 1e-25 90.1 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI43888.1 - 3.2e-09 36.5 10.0 5.6e-09 35.7 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KPI43889.1 - 5.8e-25 87.7 55.2 5.8e-24 84.4 34.1 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KPI43889.1 - 6e-21 74.2 26.3 7.7e-21 73.9 18.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UIM PF02809.15 KPI43890.1 - 0.0037 16.6 2.7 0.014 14.9 1.9 2.1 1 0 0 1 1 1 1 Ubiquitin interaction motif Paramyxo_P PF01806.12 KPI43890.1 - 0.047 12.9 0.0 0.07 12.3 0.0 1.2 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region zf-Mss51 PF13824.1 KPI43891.1 - 1.2e-26 92.2 7.8 3.5e-26 90.8 5.4 1.9 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KPI43891.1 - 0.0005 19.8 1.1 0.0011 18.7 0.8 1.6 1 0 0 1 1 1 1 MYND finger SMC_Nse1 PF07574.8 KPI43892.1 - 1.6e-30 106.2 0.1 3.3e-30 105.1 0.1 1.5 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 KPI43892.1 - 3.1e-11 43.0 9.6 4.8e-11 42.4 6.6 1.3 1 0 0 1 1 1 1 RING-like domain zf-rbx1 PF12678.2 KPI43892.1 - 0.0053 16.8 3.2 0.01 15.9 2.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-HC5HC2H_2 PF13832.1 KPI43892.1 - 0.015 15.2 3.9 0.02 14.9 1.8 1.9 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-Apc11 PF12861.2 KPI43892.1 - 0.025 14.4 2.4 0.042 13.6 1.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KPI43892.1 - 0.026 14.3 9.7 0.048 13.4 6.7 1.5 1 0 0 1 1 1 0 Ring finger domain MSP7_C PF12948.2 KPI43892.1 - 0.05 13.8 0.0 0.093 12.9 0.0 1.4 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain Baculo_IE-1 PF05290.6 KPI43892.1 - 0.081 12.6 1.1 0.15 11.7 0.8 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-HC5HC2H PF13771.1 KPI43892.1 - 0.17 12.0 6.5 0.61 10.2 4.6 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_4 PF14570.1 KPI43892.1 - 2.1 7.9 7.2 4.6 6.9 5.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 KPI43892.1 - 6.1 6.5 9.8 13 5.5 6.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cut8_C PF08559.5 KPI43893.1 - 5e-44 149.5 0.0 8.3e-44 148.8 0.0 1.4 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 KPI43893.1 - 6.3e-13 48.2 0.7 1.6e-12 47.0 0.5 1.7 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 KPI43893.1 - 0.16 11.9 5.7 0.39 10.7 4.0 1.6 1 0 0 1 1 1 0 Cut8 proteasome-binding domain CN_hydrolase PF00795.17 KPI43895.1 - 4.4e-24 84.8 0.0 7.4e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase EHN PF06441.7 KPI43896.1 - 3.1e-31 107.5 0.0 4.3e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KPI43896.1 - 1.4e-10 41.4 0.0 2.2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI43896.1 - 7.9e-08 32.1 0.1 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI43896.1 - 1.3e-06 28.2 0.0 1.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KPI43896.1 - 0.033 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase RTA1 PF04479.8 KPI43898.1 - 4.3e-32 111.4 1.6 7e-32 110.7 1.1 1.3 1 0 0 1 1 1 1 RTA1 like protein Pkinase PF00069.20 KPI43899.1 - 1.9e-18 66.5 0.0 3.4e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI43899.1 - 1.6e-09 37.2 0.0 5.1e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PX PF00787.19 KPI43900.1 - 8.1e-22 77.1 0.1 8.7e-22 77.0 0.1 1.0 1 0 0 1 1 1 1 PX domain FAM91_N PF14647.1 KPI43900.1 - 0.12 11.4 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 FAM91 N-terminus MoaE PF02391.12 KPI43901.1 - 2e-28 98.5 0.0 3e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 MoaE protein DUF4632 PF15451.1 KPI43901.1 - 0.025 14.4 0.7 0.076 12.9 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) FoP_duplication PF13865.1 KPI43901.1 - 0.051 14.0 0.9 0.12 12.7 0.6 1.7 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 FCH PF00611.18 KPI43902.1 - 6.6e-21 74.2 0.0 1.6e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KPI43902.1 - 8.5e-11 41.0 0.0 2.1e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KPI43902.1 - 1.7e-10 40.2 0.2 1.5e-09 37.1 0.0 2.6 3 0 0 3 3 3 1 Variant SH3 domain SH3_9 PF14604.1 KPI43902.1 - 1.3e-09 37.4 0.1 3.7e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain DUF778 PF05608.7 KPI43902.1 - 0.035 14.0 0.4 0.077 12.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Vps39_2 PF10367.4 KPI43904.1 - 1.6e-08 34.7 0.1 4.9e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KPI43904.1 - 0.028 14.4 0.1 0.64 10.0 0.0 2.5 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_4 PF07721.9 KPI43904.1 - 0.25 11.8 1.9 4.3 8.0 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Cyto_heme_lyase PF01265.12 KPI43907.1 - 1.7e-32 113.0 2.8 1.9e-32 112.8 1.9 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase HSP70 PF00012.15 KPI43908.1 - 3.3e-52 177.2 13.9 5.4e-50 169.9 3.1 3.2 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 KPI43908.1 - 0.00044 18.9 0.2 0.001 17.7 0.1 1.6 1 0 0 1 1 1 1 MreB/Mbl protein DUF3138 PF11336.3 KPI43908.1 - 0.17 10.0 3.1 0.41 8.7 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Rad51 PF08423.6 KPI43909.1 - 3.2e-139 462.0 0.0 3.9e-139 461.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KPI43909.1 - 2e-14 53.4 0.0 2.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KPI43909.1 - 2.2e-09 36.8 0.0 3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 KPI43909.1 - 1.3e-07 31.6 0.4 4.5e-07 29.9 0.3 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 KPI43909.1 - 4.7e-07 29.1 0.0 7.2e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 KaiC PAXNEB PF05625.6 KPI43909.1 - 0.012 14.4 0.1 0.043 12.6 0.0 1.7 2 0 0 2 2 2 0 PAXNEB protein DnaB_C PF03796.10 KPI43909.1 - 0.042 12.7 0.2 0.089 11.6 0.0 1.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain UFD1 PF03152.9 KPI43910.1 - 1.5e-23 82.8 0.0 3e-20 72.1 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin fusion degradation protein UFD1 zf-TRAF PF02176.13 KPI43910.1 - 0.47 10.8 19.1 0.093 13.1 1.1 3.3 3 0 0 3 3 3 0 TRAF-type zinc finger DUF4428 PF14471.1 KPI43910.1 - 1.2 8.9 4.1 5.5 6.8 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4428) E1_DerP2_DerF2 PF02221.10 KPI43911.1 - 8.3e-18 64.9 0.8 3.9e-17 62.7 0.6 1.9 1 1 0 1 1 1 1 ML domain TRP_N PF14558.1 KPI43911.1 - 0.0046 16.9 0.1 0.015 15.3 0.1 2.0 1 1 0 1 1 1 1 ML-like domain FHIPEP PF00771.15 KPI43911.1 - 0.064 11.5 0.0 0.072 11.4 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family ERG4_ERG24 PF01222.12 KPI43913.1 - 3.2e-140 467.4 19.6 4.1e-140 467.1 13.6 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family FAD_binding_3 PF01494.14 KPI43913.1 - 6.8e-20 71.4 2.3 3.6e-14 52.5 0.2 3.0 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.19 KPI43913.1 - 5.4e-13 48.5 2.7 5.6e-07 28.7 0.2 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 KPI43913.1 - 2.3e-07 29.9 0.0 2e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.22 KPI43913.1 - 4.3e-06 27.0 0.2 0.0006 20.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI43913.1 - 9.2e-06 25.6 0.1 2.7e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI43913.1 - 0.00023 20.1 0.7 0.0004 19.3 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 KPI43913.1 - 0.0011 18.4 0.1 0.0021 17.5 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 KPI43913.1 - 0.0013 18.6 0.1 0.0023 17.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI43913.1 - 0.0018 17.1 0.1 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 KPI43913.1 - 0.0026 16.3 0.1 0.13 10.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KPI43913.1 - 0.0059 16.6 0.1 0.015 15.3 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KPI43913.1 - 0.012 14.7 1.4 0.26 10.3 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_10 PF13460.1 KPI43913.1 - 0.02 14.8 0.2 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding FAD_oxidored PF12831.2 KPI43913.1 - 0.04 13.0 1.1 0.06 12.4 0.7 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KPI43913.1 - 0.14 11.0 0.0 0.28 10.0 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 KPI43913.1 - 0.15 10.6 0.6 1.2 7.6 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 KPI43913.1 - 0.22 11.1 0.1 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Clr5 PF14420.1 KPI43914.1 - 3.9e-07 29.8 1.5 6.6e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 Clr5 domain TPR_12 PF13424.1 KPI43914.1 - 1.9e-06 27.7 2.7 0.067 13.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 KPI43914.1 - 0.24 11.3 9.1 0.95 9.4 0.3 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat CBFD_NFYB_HMF PF00808.18 KPI43915.1 - 1.8e-13 50.3 2.0 3.2e-11 43.1 0.5 2.4 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Xpo1 PF08389.7 KPI43915.1 - 0.041 13.7 0.1 0.049 13.5 0.1 1.2 1 0 0 1 1 1 0 Exportin 1-like protein Bromo_TP PF07524.8 KPI43915.1 - 0.043 13.5 0.2 0.075 12.7 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated UBX PF00789.15 KPI43916.1 - 3.3e-12 46.2 0.0 7.1e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 KPI43916.1 - 1e-09 37.7 0.1 1.9e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain RR_TM4-6 PF06459.7 KPI43916.1 - 0.11 12.3 2.6 0.17 11.7 1.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paramyxo_ncap PF00973.14 KPI43916.1 - 0.73 8.4 4.7 1 8.0 3.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein ApbA_C PF08546.6 KPI43917.1 - 2.2e-28 98.7 0.1 3.4e-28 98.1 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KPI43917.1 - 9.6e-25 86.7 0.0 7.5e-24 83.8 0.0 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA MMR_HSR1_C PF08438.5 KPI43917.1 - 0.095 12.9 0.2 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 GTPase of unknown function C-terminal TrkA_N PF02254.13 KPI43917.1 - 0.13 12.2 0.0 0.52 10.3 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain ADH_zinc_N PF00107.21 KPI43918.1 - 6e-28 96.9 0.0 1.5e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI43918.1 - 1.7e-08 35.3 0.0 4.1e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF469 PF04320.9 KPI43918.1 - 0.12 13.1 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein with unknown function (DUF469) Mito_carr PF00153.22 KPI43919.1 - 8.1e-41 137.6 0.9 6.9e-21 73.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1772 PF08592.6 KPI43921.1 - 1.2e-10 41.2 8.5 3.4e-10 39.8 5.9 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Pyr_redox_3 PF13738.1 KPI43922.1 - 2e-26 93.2 0.0 5.3e-26 91.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI43922.1 - 2.9e-11 42.3 0.0 3.5e-08 32.1 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI43922.1 - 5.5e-10 39.1 0.1 4.3e-09 36.2 0.0 2.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI43922.1 - 5.8e-09 36.1 0.0 8.3e-07 29.0 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI43922.1 - 5.3e-06 26.2 0.1 0.017 14.8 0.1 4.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KPI43922.1 - 0.00021 20.3 0.0 0.0037 16.2 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 KPI43922.1 - 0.00038 20.6 0.0 0.55 10.5 0.0 2.7 2 0 0 2 2 2 2 Putative NAD(P)-binding DAO PF01266.19 KPI43922.1 - 0.0007 18.5 0.7 0.0023 16.8 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KPI43922.1 - 0.0033 17.7 0.3 1.1 9.7 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI43922.1 - 0.0038 16.3 0.0 0.2 10.7 0.0 2.7 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.15 KPI43922.1 - 0.011 15.7 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 KPI43922.1 - 0.014 14.3 0.0 0.054 12.3 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.14 KPI43922.1 - 0.029 13.5 0.1 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KPI43922.1 - 0.04 12.8 0.0 0.14 11.0 0.0 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KPI43922.1 - 0.43 9.5 2.8 1.9 7.4 0.1 2.6 2 1 1 3 3 3 0 FAD binding domain RIC1 PF07064.8 KPI43923.1 - 5.4e-10 39.1 0.1 5.3e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 RIC1 PBP1_TM PF14812.1 KPI43923.1 - 0.08 13.2 3.0 0.17 12.2 2.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 KPI43923.1 - 0.42 8.4 8.2 0.52 8.1 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 KPI43923.1 - 0.43 9.5 2.4 0.53 9.2 1.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.9 KPI43923.1 - 0.43 8.5 4.3 0.54 8.2 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 KPI43923.1 - 0.44 10.5 3.5 0.62 10.0 2.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Tom22 PF04281.8 KPI43923.1 - 1.3 8.5 8.1 1.9 8.0 5.6 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Daxx PF03344.10 KPI43923.1 - 1.3 7.3 6.8 1.7 7.0 4.7 1.1 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 KPI43923.1 - 4.5 6.3 11.8 7.4 5.6 8.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 KPI43923.1 - 5.7 5.5 12.2 7.7 5.1 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PAP_assoc PF03828.14 KPI43924.1 - 6.7e-06 25.9 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KPI43924.1 - 1.3e-05 25.4 0.0 2.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.12 KPI43924.1 - 0.0065 15.3 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain Pkinase PF00069.20 KPI43925.1 - 9.6e-69 231.4 0.0 1.2e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI43925.1 - 2.7e-29 102.0 0.0 3.5e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI43925.1 - 3.8e-07 29.3 0.0 5.1e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KPI43925.1 - 0.00025 20.8 0.1 0.00043 20.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KPI43925.1 - 0.0015 17.6 0.0 0.0028 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KPI43925.1 - 0.051 12.9 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL NmrA PF05368.8 KPI43926.1 - 5.1e-27 94.6 0.0 6.2e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI43926.1 - 8.9e-08 32.3 0.0 1.4e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI43926.1 - 2.5e-05 23.8 0.1 5.2e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KPI43926.1 - 4.9e-05 23.6 0.0 0.00035 20.8 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KPI43926.1 - 0.00049 18.9 0.3 0.00068 18.4 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KPI43926.1 - 0.00063 18.7 0.1 0.00083 18.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KPI43926.1 - 0.0016 18.1 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 KR domain DapB_N PF01113.15 KPI43926.1 - 0.016 15.1 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 KPI43926.1 - 0.04 13.8 0.1 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.7 KPI43926.1 - 0.098 11.5 0.0 0.39 9.6 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein GFO_IDH_MocA PF01408.17 KPI43926.1 - 0.11 13.0 0.0 0.44 11.0 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Glyco_hydro_47 PF01532.15 KPI43927.1 - 1.9e-123 412.4 0.0 2.4e-123 412.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RRM_5 PF13893.1 KPI43929.1 - 3.9e-09 36.2 0.0 6.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KPI43929.1 - 8.4e-09 34.9 0.0 1.4e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI43929.1 - 0.00012 22.0 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KPI43929.1 - 0.00016 21.3 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KPI43929.1 - 0.094 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif zf-CCHC_6 PF15288.1 KPI43930.1 - 0.011 15.3 4.5 0.026 14.1 3.1 1.6 1 0 0 1 1 1 0 Zinc knuckle FMN_dh PF01070.13 KPI43931.1 - 4e-121 404.1 0.0 5.3e-121 403.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KPI43931.1 - 2.3e-22 78.5 0.0 4.3e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KPI43931.1 - 1.1e-08 34.4 0.1 2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KPI43931.1 - 9e-05 21.5 0.5 0.00042 19.3 0.1 2.2 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KPI43931.1 - 0.0078 15.3 1.1 0.0091 15.1 0.2 1.5 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 KPI43931.1 - 0.059 12.6 0.7 1.1 8.5 0.1 2.3 1 1 1 2 2 2 0 Histidine biosynthesis protein DNA_pol_B_palm PF14792.1 KPI43932.1 - 4.6e-30 103.9 0.0 2.3e-29 101.6 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase beta palm HHH_8 PF14716.1 KPI43932.1 - 1.8e-16 60.0 1.7 4e-16 58.9 1.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 KPI43932.1 - 8e-16 57.3 0.0 8e-16 57.3 0.0 2.3 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 KPI43932.1 - 3.4e-09 36.2 0.2 8.1e-09 35.0 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb BRCT PF00533.21 KPI43932.1 - 0.00034 20.6 0.0 0.00099 19.2 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.18 KPI43932.1 - 0.029 14.6 0.0 0.082 13.2 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH_5 PF14520.1 KPI43932.1 - 0.11 12.7 0.2 4.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain Gtr1_RagA PF04670.7 KPI43933.1 - 1.9e-59 200.5 0.1 2.8e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KPI43933.1 - 1.5e-05 25.4 0.0 3.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KPI43933.1 - 0.0018 17.5 0.0 0.0032 16.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KPI43933.1 - 0.01 15.7 0.0 0.042 13.7 0.0 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 KPI43933.1 - 0.026 14.4 0.0 0.12 12.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF162 PF02589.10 KPI43934.1 - 0.056 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised ACR, YkgG family COG1556 Fungal_trans_2 PF11951.3 KPI43935.1 - 0.00032 19.4 1.1 0.00052 18.7 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KPI43936.1 - 2e-09 36.7 2.1 3.7e-09 35.8 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI43936.1 - 8e-09 35.2 7.2 1.4e-08 34.5 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 KPI43937.1 - 2.2e-40 138.5 54.2 2.5e-39 135.0 37.6 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI43937.1 - 2.8e-17 62.2 47.1 2e-16 59.4 32.7 1.9 1 1 0 1 1 1 1 Amino acid permease p450 PF00067.17 KPI43938.1 - 4.5e-66 223.2 0.0 5.2e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pyridoxal_deC PF00282.14 KPI43939.1 - 2.6e-111 371.6 0.0 3.2e-111 371.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 KPI43939.1 - 0.0073 15.2 0.0 0.017 14.0 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II DUF1908 PF08926.6 KPI43939.1 - 0.16 10.6 0.0 0.28 9.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Fungal_trans_2 PF11951.3 KPI43940.1 - 2.4e-10 39.5 0.0 4.2e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 KPI43941.1 - 3.1e-14 52.8 1.2 4.9e-12 45.5 0.9 3.1 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KPI43941.1 - 8.8e-08 31.3 0.2 1.9e-07 30.3 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KPI43941.1 - 7.5e-07 29.0 0.1 2.2e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI43941.1 - 2e-06 26.9 0.2 1.1e-05 24.5 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KPI43941.1 - 2.3e-05 23.6 0.4 5.4e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI43941.1 - 4e-05 23.5 0.1 0.00013 21.9 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI43941.1 - 0.00016 21.9 0.1 0.011 16.1 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI43941.1 - 0.0004 18.9 0.1 0.00077 18.0 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KPI43941.1 - 0.0014 17.6 0.1 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KPI43941.1 - 0.0017 17.4 0.1 0.0032 16.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 KPI43941.1 - 0.0085 16.1 0.0 0.019 14.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TauD PF02668.11 KPI43942.1 - 2.8e-52 177.9 0.3 3.4e-52 177.6 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 KPI43942.1 - 0.034 14.6 0.1 1.3 9.6 0.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily VPS9 PF02204.13 KPI43943.1 - 2.5e-30 104.5 0.0 4.4e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 KPI43943.1 - 5.8e-08 32.0 0.0 1.2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 CUE domain TMA7 PF09072.5 KPI43944.1 - 1.6e-26 92.5 23.7 1.8e-26 92.3 16.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Cyt-b5 PF00173.23 KPI43945.1 - 2.1e-11 43.4 0.0 3.1e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain H2TH PF06831.9 KPI43946.1 - 1.1e-21 76.3 0.0 2.2e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 KPI43946.1 - 3e-21 75.9 0.0 5.2e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain FbpA PF05833.6 KPI43946.1 - 0.00084 17.9 0.0 0.0013 17.3 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Amidohydro_2 PF04909.9 KPI43947.1 - 1.5e-39 136.1 0.2 1.8e-39 135.9 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase F-box PF00646.28 KPI43948.1 - 0.00056 19.4 0.7 0.0031 17.1 0.1 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KPI43948.1 - 0.0032 17.1 0.0 0.012 15.3 0.0 2.0 1 0 0 1 1 1 1 F-box-like DUF3760 PF12586.3 KPI43948.1 - 0.045 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) Pyr_redox_3 PF13738.1 KPI43950.1 - 9.3e-23 81.3 0.0 1.4e-20 74.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI43950.1 - 2e-14 53.2 0.0 1.7e-12 46.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KPI43950.1 - 4.1e-13 49.6 0.0 2.3e-11 43.9 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI43950.1 - 6.8e-12 44.3 0.0 4.8e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 KPI43950.1 - 1.7e-06 27.9 0.0 0.017 14.8 0.1 3.1 2 1 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KPI43950.1 - 2.6e-05 24.1 0.0 8.4e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KPI43950.1 - 0.00018 20.6 0.0 0.00029 20.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KPI43950.1 - 0.00026 19.5 0.0 1.3 7.4 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.19 KPI43950.1 - 0.00035 19.5 0.0 0.84 8.4 0.0 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KPI43950.1 - 0.0036 17.6 0.2 2.9 8.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI43950.1 - 0.0069 15.2 0.0 8.5 5.1 0.0 3.7 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KPI43950.1 - 0.03 13.1 0.0 0.067 12.0 0.0 1.5 1 1 1 2 2 2 0 FAD binding domain DIOX_N PF14226.1 KPI43951.1 - 9.6e-21 74.4 0.0 1.5e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI43951.1 - 1.6e-16 60.4 0.0 4.9e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Peptidase_M28 PF04389.12 KPI43952.1 - 3e-31 108.5 0.0 5e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KPI43952.1 - 0.046 13.2 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 ADH_N PF08240.7 KPI43954.1 - 6.6e-27 93.4 1.2 1.4e-26 92.3 0.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI43954.1 - 1.2e-15 57.1 0.0 2.4e-15 56.2 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Tctex-1 PF03645.8 KPI43955.1 - 5.3e-30 103.2 0.0 7.5e-30 102.7 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family bZIP_1 PF00170.16 KPI43956.1 - 0.00034 20.5 15.1 0.0006 19.7 10.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KPI43956.1 - 0.00053 19.7 14.6 0.001 18.8 10.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper HAD_2 PF13419.1 KPI43957.1 - 1.1e-19 71.3 0.1 4.3e-16 59.6 0.0 2.0 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KPI43957.1 - 7.1e-08 33.1 0.0 9.6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KPI43957.1 - 0.03 14.0 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Sugar_tr PF00083.19 KPI43958.1 - 1.8e-35 122.4 23.1 5.2e-35 120.8 16.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI43958.1 - 6.8e-32 110.5 25.3 1.5e-25 89.6 10.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2306 PF10067.4 KPI43958.1 - 0.04 14.0 0.7 1.2 9.2 0.0 3.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) Mononeg_RNA_pol PF00946.14 KPI43958.1 - 0.23 8.8 0.1 0.32 8.3 0.1 1.1 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase Glyco_transf_34 PF05637.7 KPI43959.1 - 2.4e-13 50.1 2.5 3e-06 26.9 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 KPI43959.1 - 3.4e-07 29.8 0.0 5.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF273 AAA_2 PF07724.9 KPI43960.1 - 2.9e-47 160.7 0.0 6.2e-46 156.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KPI43960.1 - 2.4e-24 85.0 0.1 8.9e-24 83.2 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KPI43960.1 - 2e-19 70.1 0.1 3.8e-09 36.8 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KPI43960.1 - 2.3e-14 53.2 0.3 2.3e-09 37.0 0.0 3.4 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KPI43960.1 - 1.7e-12 47.6 0.0 4.3e-05 23.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KPI43960.1 - 9e-12 45.3 8.6 0.00012 22.0 0.0 4.6 3 2 2 5 5 5 3 AAA ATPase domain Sigma54_activat PF00158.21 KPI43960.1 - 2.9e-08 33.3 0.2 0.00016 21.1 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 KPI43960.1 - 1.8e-07 31.1 0.0 0.021 14.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KPI43960.1 - 4.1e-07 30.8 1.6 0.011 16.5 0.0 3.6 3 2 0 3 3 2 2 AAA domain AAA_18 PF13238.1 KPI43960.1 - 6.5e-07 29.6 1.2 0.051 13.8 0.0 3.4 3 0 0 3 3 2 2 AAA domain Arch_ATPase PF01637.13 KPI43960.1 - 6.7e-06 25.9 7.1 0.1 12.2 0.0 4.7 3 2 0 3 3 3 2 Archaeal ATPase AAA_28 PF13521.1 KPI43960.1 - 1.2e-05 25.2 0.3 0.064 13.2 0.0 3.6 3 1 0 3 3 3 1 AAA domain NACHT PF05729.7 KPI43960.1 - 1.7e-05 24.5 0.1 0.12 12.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain IstB_IS21 PF01695.12 KPI43960.1 - 4.9e-05 22.8 0.0 0.085 12.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 KPI43960.1 - 8.8e-05 22.1 0.0 0.014 15.1 0.0 3.1 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 KPI43960.1 - 9.8e-05 22.0 0.0 0.043 13.5 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KPI43960.1 - 0.0001 22.5 2.0 0.62 10.3 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_25 PF13481.1 KPI43960.1 - 0.00012 21.5 0.1 0.44 9.9 0.1 3.1 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KPI43960.1 - 0.00058 20.0 0.0 0.31 11.2 0.0 2.8 2 1 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 KPI43960.1 - 0.0007 18.8 0.1 4.6 6.3 0.0 3.8 3 1 1 4 4 4 0 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.4 KPI43960.1 - 0.0015 17.2 0.0 0.13 10.8 0.0 2.6 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 KPI43960.1 - 0.0038 16.8 0.0 0.27 10.7 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KPI43960.1 - 0.0052 16.6 0.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 KPI43960.1 - 0.0076 15.7 0.0 1.2 8.5 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_23 PF13476.1 KPI43960.1 - 0.0092 16.3 12.3 0.59 10.4 8.3 2.7 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 KPI43960.1 - 0.0094 16.4 0.7 1.2 9.7 0.0 3.1 3 0 0 3 3 3 1 Miro-like protein DUF258 PF03193.11 KPI43960.1 - 0.012 14.7 0.0 3.1 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ResIII PF04851.10 KPI43960.1 - 0.017 14.9 3.2 3 7.6 0.1 3.3 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.4 KPI43960.1 - 0.023 14.2 0.1 1.9 7.9 0.0 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KPI43960.1 - 0.024 14.1 0.0 0.44 10.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PIF1 PF05970.9 KPI43960.1 - 0.026 13.4 0.0 1.3 7.9 0.0 2.5 3 0 0 3 3 3 0 PIF1-like helicase PhoH PF02562.11 KPI43960.1 - 0.026 13.7 0.0 0.89 8.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DUF815 PF05673.8 KPI43960.1 - 0.029 13.2 0.3 0.55 9.1 0.1 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF815) UPF0079 PF02367.12 KPI43960.1 - 0.032 13.8 0.0 9.8 5.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 KPI43960.1 - 0.032 13.6 0.1 0.43 9.9 0.0 2.9 2 2 0 2 2 2 0 AAA-like domain AAA_24 PF13479.1 KPI43960.1 - 0.038 13.5 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 KPI43960.1 - 0.05 12.6 2.6 0.22 10.5 0.8 2.3 2 1 0 2 2 1 0 AAA ATPase domain AAA_29 PF13555.1 KPI43960.1 - 0.065 12.7 0.0 4.3 6.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain UvrD-helicase PF00580.16 KPI43960.1 - 0.1 11.8 3.8 0.44 9.7 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Rootletin PF15035.1 KPI43960.1 - 0.26 11.2 10.7 0.6 10.0 7.4 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion GrpE PF01025.14 KPI43960.1 - 0.85 9.1 7.3 2 7.9 4.4 2.2 2 0 0 2 2 2 0 GrpE DivIC PF04977.10 KPI43960.1 - 7.7 6.0 12.4 6 6.4 4.4 2.4 1 1 1 2 2 2 0 Septum formation initiator AMP-binding PF00501.23 KPI43961.1 - 1.7e-90 303.3 0.0 2.2e-90 303.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI43961.1 - 1.1e-08 35.8 0.0 2.7e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MTHFR PF02219.12 KPI43962.1 - 1.4e-115 385.3 0.0 1.9e-115 384.9 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase SCO1-SenC PF02630.9 KPI43965.1 - 6.3e-56 188.7 0.0 8.1e-56 188.3 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KPI43965.1 - 5.9e-05 22.7 0.0 8.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KPI43965.1 - 0.0018 18.3 0.0 0.0037 17.3 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like FAD_binding_3 PF01494.14 KPI43966.1 - 2.7e-93 312.8 0.0 3.9e-93 312.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KPI43966.1 - 0.00043 20.6 0.0 0.6 10.5 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI43966.1 - 0.0007 18.5 0.0 0.13 11.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI43966.1 - 0.0014 18.5 0.1 0.0038 17.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI43966.1 - 0.0082 16.1 0.6 0.024 14.6 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KPI43966.1 - 0.0089 16.1 0.0 0.028 14.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI43966.1 - 0.032 13.1 0.1 0.062 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KPI43966.1 - 0.16 11.0 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DUF1684 PF07920.6 KPI43967.1 - 0.01 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1684) Aminotran_4 PF01063.14 KPI43968.1 - 6.5e-35 120.6 0.0 8e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV DUF4448 PF14610.1 KPI43970.1 - 2.4e-05 23.9 0.0 3.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 KPI43970.1 - 0.00027 20.6 0.6 0.00027 20.6 0.4 2.4 2 1 0 2 2 2 1 TMEM154 protein family SKG6 PF08693.5 KPI43970.1 - 0.00046 19.4 4.4 0.00096 18.4 3.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1180 PF06679.7 KPI43970.1 - 0.0018 18.1 1.7 0.0018 18.1 1.1 2.9 3 1 1 4 4 4 1 Protein of unknown function (DUF1180) DAP10 PF07213.6 KPI43970.1 - 0.0087 15.7 0.9 0.021 14.5 0.6 1.6 1 0 0 1 1 1 1 DAP10 membrane protein RCR PF12273.3 KPI43970.1 - 0.014 15.9 1.1 0.014 15.9 0.8 2.4 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Sarcoglycan_2 PF05510.8 KPI43970.1 - 0.027 12.7 0.0 0.039 12.2 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Hum_adeno_E3A PF05393.6 KPI43970.1 - 0.24 11.0 0.7 1.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein TMEM51 PF15345.1 KPI43970.1 - 0.47 10.1 6.9 0.12 12.0 0.2 2.4 2 1 0 2 2 2 0 Transmembrane protein 51 Adeno_E3_CR2 PF02439.10 KPI43970.1 - 7.2 6.2 6.4 0.9 9.1 1.3 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Nol1_Nop2_Fmu PF01189.12 KPI43972.1 - 1.2e-24 87.1 0.0 1.8e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KPI43972.1 - 4.2e-08 33.2 0.0 6.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KPI43972.1 - 7.9e-06 25.3 0.0 1.6e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KPI43972.1 - 4.7e-05 23.4 0.0 7.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 KPI43972.1 - 0.0083 16.7 0.0 0.017 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KPI43972.1 - 0.068 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DUF1542 PF07564.6 KPI43973.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) NmrA PF05368.8 KPI43974.1 - 1e-12 47.7 0.0 1.4e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family AA_permease_2 PF13520.1 KPI43975.1 - 2.4e-54 184.5 57.3 3.1e-54 184.1 39.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI43975.1 - 6e-16 57.8 47.0 8.5e-16 57.3 32.5 1.1 1 0 0 1 1 1 1 Amino acid permease rRNA_proc-arch PF13234.1 KPI43976.1 - 4.2e-90 301.5 0.1 1.1e-89 300.1 0.0 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 KPI43976.1 - 1.6e-63 213.1 0.7 4.4e-63 211.7 0.5 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KPI43976.1 - 6.6e-22 77.7 0.2 1.7e-21 76.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI43976.1 - 8.9e-07 28.6 0.0 2.4e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI43976.1 - 0.0005 19.9 0.0 0.0054 16.5 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 KPI43976.1 - 0.0043 15.9 0.0 0.013 14.3 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 KPI43976.1 - 0.048 12.7 0.3 1.3 8.1 0.0 2.5 2 0 0 2 2 2 0 KaiC UPF0075 PF03702.9 KPI43977.1 - 7.9e-60 202.6 0.0 9.2e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) FGGY_C PF02782.11 KPI43977.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain MFS_1 PF07690.11 KPI43978.1 - 3.2e-25 88.5 19.8 3.2e-25 88.5 13.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DAO PF01266.19 KPI43979.1 - 4.4e-29 101.4 1.4 1e-28 100.3 1.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.21 KPI43979.1 - 6.6e-10 38.4 0.0 1.4e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.1 KPI43979.1 - 3.1e-09 36.7 0.3 8.7e-09 35.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI43979.1 - 2.2e-06 26.7 0.3 3.5e-06 26.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 KPI43979.1 - 9.7e-06 24.8 0.1 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KPI43979.1 - 1.5e-05 24.9 0.1 3.5e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI43979.1 - 5.1e-05 22.4 0.0 8.9e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KPI43979.1 - 0.00098 18.3 0.1 0.0017 17.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KPI43979.1 - 0.0017 18.7 0.2 0.0061 16.9 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KPI43979.1 - 0.0026 16.8 1.4 0.0084 15.2 0.1 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 KPI43979.1 - 0.013 14.0 0.2 0.018 13.5 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 KPI43979.1 - 0.016 15.2 0.2 0.046 13.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI43979.1 - 0.074 11.9 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KPI43979.1 - 0.1 11.4 0.2 0.19 10.5 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KPI43979.1 - 0.12 12.1 1.0 0.21 11.3 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding LacAB_rpiB PF02502.13 KPI43980.1 - 9.7e-45 151.6 0.5 1.1e-44 151.4 0.4 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.1 KPI43980.1 - 0.015 15.2 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Glycine-rich SFCGS DUF2620 PF10941.3 KPI43980.1 - 0.18 11.8 2.1 0.16 12.0 0.5 1.8 2 1 0 2 2 2 0 Protein of unknown function DUF2620 DUF4599 PF15371.1 KPI43981.1 - 0.0045 17.0 3.4 0.43 10.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4599) Hemerythrin PF01814.18 KPI43981.1 - 0.086 12.9 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain AA_permease_2 PF13520.1 KPI43982.1 - 1.3e-53 182.1 53.4 1.6e-53 181.8 37.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI43982.1 - 3.6e-24 84.9 40.6 4.9e-24 84.5 28.1 1.1 1 0 0 1 1 1 1 Amino acid permease GHMP_kinases_N PF00288.21 KPI43984.1 - 5.4e-09 35.9 0.9 1.3e-08 34.8 0.6 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KPI43984.1 - 0.0018 18.4 0.0 0.01 16.0 0.0 2.2 3 0 0 3 3 3 1 GHMP kinases C terminal COesterase PF00135.23 KPI43985.1 - 1.4e-64 218.7 1.4 1.4e-62 212.1 0.2 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI43985.1 - 5.4e-10 39.1 0.1 1.4e-09 37.8 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DHO_dh PF01180.16 KPI43986.1 - 2.6e-39 134.9 0.0 6.6e-28 97.5 0.0 2.2 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 KPI43986.1 - 1e-06 28.2 0.3 0.012 14.9 0.0 2.3 2 0 0 2 2 2 2 PcrB family Vfa1 PF08432.5 KPI43986.1 - 0.071 13.1 3.7 0.11 12.4 2.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FH2 PF02181.18 KPI43986.1 - 0.11 11.4 1.3 0.15 10.8 0.9 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF3138 PF11336.3 KPI43986.1 - 0.16 10.0 2.9 0.24 9.5 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FGF-BP1 PF06473.7 KPI43986.1 - 0.2 11.2 1.4 0.37 10.3 1.0 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF4407 PF14362.1 KPI43986.1 - 0.3 10.0 4.7 0.42 9.5 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IFT20 PF14931.1 KPI43986.1 - 0.82 9.5 7.7 0.61 9.9 4.2 1.6 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 HALZ PF02183.13 KPI43986.1 - 2.7 7.7 6.4 0.23 11.2 0.5 2.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper MFS_1 PF07690.11 KPI43987.1 - 2.4e-30 105.4 49.1 2.4e-30 105.4 34.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldolase_II PF00596.16 KPI43988.1 - 1.3e-46 158.4 0.1 1.7e-46 158.1 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DIOX_N PF14226.1 KPI43989.1 - 7.6e-20 71.5 0.0 1.3e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI43989.1 - 3.5e-17 62.5 0.0 5.6e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DHO_dh PF01180.16 KPI43990.1 - 7.7e-11 41.4 0.1 9.9e-11 41.1 0.1 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase bPH_5 PF10882.3 KPI43990.1 - 0.038 13.7 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain AIF-MLS PF14962.1 KPI43990.1 - 0.12 11.9 0.2 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Hexapep PF00132.19 KPI43991.1 - 4.7e-08 32.1 6.7 0.0018 17.7 0.7 4.0 1 1 4 5 5 5 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KPI43991.1 - 0.0013 18.8 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 KPI43991.1 - 0.22 10.0 0.4 0.33 9.4 0.3 1.2 1 0 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.1 KPI43991.1 - 2 8.0 16.1 0.29 10.7 0.9 3.6 2 1 2 4 4 4 0 Hexapeptide repeat of succinyl-transferase Pyr_redox_2 PF07992.9 KPI43992.1 - 9.1e-21 74.6 0.0 1.1e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI43992.1 - 2.2e-08 34.3 3.5 3.5e-07 30.5 0.1 3.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI43992.1 - 4.9e-05 23.4 0.0 0.00026 21.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAA_hydrolase PF01557.13 KPI43993.1 - 3.8e-23 82.1 0.1 6e-23 81.4 0.1 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_6 PF12697.2 KPI43993.1 - 7.8e-23 81.5 3.0 6.5e-22 78.5 0.5 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI43993.1 - 1.9e-13 50.5 0.1 3.1e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI43993.1 - 1.1e-11 44.7 0.2 1.1e-09 38.2 0.0 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KPI43993.1 - 1.1e-05 25.1 0.7 0.00011 21.8 0.5 2.2 1 1 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.8 KPI43993.1 - 0.00081 19.0 0.2 0.002 17.7 0.2 1.7 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_4 PF08386.5 KPI43993.1 - 0.0036 17.1 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.11 KPI43993.1 - 0.012 15.0 0.1 4.8 6.5 0.0 2.6 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_8 PF06259.7 KPI43993.1 - 0.053 13.0 1.4 0.2 11.1 0.1 2.4 1 1 2 3 3 3 0 Alpha/beta hydrolase DUF676 PF05057.9 KPI43993.1 - 0.1 11.8 1.4 1.6 8.0 0.2 2.2 1 1 1 2 2 2 0 Putative serine esterase (DUF676) adh_short PF00106.20 KPI43995.1 - 9.5e-22 77.6 0.8 1.4e-21 77.1 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI43995.1 - 8.5e-16 58.4 0.0 2.6e-15 56.8 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI43995.1 - 2e-08 34.0 0.1 4.1e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI43995.1 - 0.0019 17.6 0.1 0.0025 17.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KPI43995.1 - 0.0067 15.3 0.0 0.0087 14.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KPI43995.1 - 0.02 14.9 1.2 0.05 13.6 0.2 2.2 2 2 0 2 2 2 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KPI43995.1 - 0.058 13.1 0.3 0.19 11.5 0.2 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KPI43995.1 - 0.085 12.0 0.2 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family AAA PF00004.24 KPI43996.1 - 3.6e-44 150.1 0.0 5.5e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KPI43996.1 - 1.3e-07 31.6 0.0 2.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KPI43996.1 - 1.3e-07 31.4 0.0 3.2e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KPI43996.1 - 1.1e-06 28.8 0.0 2.5e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KPI43996.1 - 3.7e-06 27.1 0.0 0.00017 21.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KPI43996.1 - 4.7e-05 23.0 0.1 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KPI43996.1 - 7.9e-05 23.4 0.0 0.00019 22.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KPI43996.1 - 9.4e-05 21.5 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KPI43996.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KPI43996.1 - 0.00099 17.9 0.0 0.0018 17.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KPI43996.1 - 0.0015 18.4 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KPI43996.1 - 0.0022 17.8 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KPI43996.1 - 0.0024 16.9 0.0 0.0046 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 KPI43996.1 - 0.004 16.7 0.0 0.011 15.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KPI43996.1 - 0.0042 17.0 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KPI43996.1 - 0.0066 15.6 0.1 0.015 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KPI43996.1 - 0.0066 15.5 0.0 0.016 14.2 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_18 PF13238.1 KPI43996.1 - 0.015 15.6 0.0 0.044 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KPI43996.1 - 0.015 14.7 0.1 0.082 12.3 0.0 1.9 1 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 KPI43996.1 - 0.015 14.2 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 KPI43996.1 - 0.016 14.4 0.0 0.052 12.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 KPI43996.1 - 0.019 14.4 0.0 0.086 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 KPI43996.1 - 0.024 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KPI43996.1 - 0.032 14.3 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 KPI43996.1 - 0.053 13.5 0.0 0.14 12.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 KPI43996.1 - 0.074 12.7 0.0 0.38 10.3 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 KPI43996.1 - 0.076 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KPI43996.1 - 0.092 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2072 PF09845.4 KPI43996.1 - 0.097 12.6 0.1 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) NTPase_1 PF03266.10 KPI43996.1 - 0.12 12.0 0.7 0.82 9.3 0.0 2.5 3 1 1 4 4 4 0 NTPase TBP PF00352.16 KPI43996.1 - 0.14 11.5 0.1 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIID (or TATA-binding protein, TBP) CorA PF01544.13 KPI43997.1 - 0.0013 17.8 0.2 0.0021 17.1 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein HET PF06985.6 KPI43997.1 - 0.02 15.0 2.7 0.28 11.3 1.9 2.3 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 KPI43998.1 - 5.9e-60 202.5 0.0 7.9e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI43998.1 - 2.2e-32 112.1 0.0 2.6e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI43998.1 - 3.4e-07 29.5 0.0 8.6e-06 24.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KPI43998.1 - 0.0019 17.2 0.1 0.003 16.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KPI43998.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 KPI43998.1 - 0.033 13.9 0.1 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Apc4_WD40 PF12894.2 KPI43998.1 - 0.099 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DAO PF01266.19 KPI43999.1 - 5.6e-35 120.8 0.5 7.6e-35 120.4 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI43999.1 - 5.7e-06 26.2 0.1 1.5e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KPI43999.1 - 0.00017 20.6 0.0 0.00034 19.6 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KPI43999.1 - 0.00038 20.2 0.1 0.011 15.5 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KPI43999.1 - 0.0053 16.8 0.0 0.75 9.8 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI43999.1 - 0.0071 16.7 0.2 0.015 15.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI43999.1 - 0.0073 15.1 0.1 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KPI43999.1 - 0.0074 15.4 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 KPI43999.1 - 0.0097 15.5 0.3 1.2 8.7 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 KPI43999.1 - 0.0099 14.9 0.0 0.073 12.1 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 KPI43999.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sterol_MT_C PF08498.5 KPI44000.1 - 2.1e-27 94.8 0.2 3.3e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KPI44000.1 - 1.8e-15 57.2 0.0 4.2e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI44000.1 - 5.4e-14 52.0 0.0 8.2e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI44000.1 - 6e-12 45.5 0.0 9.9e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KPI44000.1 - 6.3e-10 38.5 0.0 9e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KPI44000.1 - 2.3e-09 37.6 0.0 7.2e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI44000.1 - 4.5e-09 36.5 0.0 9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI44000.1 - 9.4e-07 29.4 0.0 2.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI44000.1 - 2.9e-06 27.3 0.0 8.3e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI44000.1 - 4e-05 22.8 0.0 6.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.11 KPI44000.1 - 0.0022 16.4 0.0 0.0032 15.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.8 KPI44000.1 - 0.0089 15.1 0.0 0.018 14.1 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KPI44000.1 - 0.029 13.7 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain LSM PF01423.17 KPI44001.1 - 2.9e-16 58.7 0.0 4.1e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain Tyr-DNA_phospho PF06087.7 KPI44002.1 - 9.9e-114 380.3 0.0 1.4e-113 379.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KPI44002.1 - 0.0015 18.2 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain Sigma70_r4_2 PF08281.7 KPI44002.1 - 0.0023 17.3 0.0 0.0055 16.1 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 ABC2_membrane PF01061.19 KPI44003.1 - 9.3e-70 234.0 65.1 3.4e-47 160.3 12.7 4.4 5 0 0 5 5 4 3 ABC-2 type transporter PDR_CDR PF06422.7 KPI44003.1 - 5.6e-31 106.2 1.6 9.8e-27 92.6 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 KPI44003.1 - 2.5e-14 53.7 0.0 4.6e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 KPI44003.1 - 2e-05 23.8 11.9 2e-05 23.8 8.3 2.9 3 1 1 4 4 4 2 ABC-2 family transporter protein DUF258 PF03193.11 KPI44003.1 - 6.8e-05 22.1 0.0 0.00013 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 KPI44003.1 - 0.00013 22.0 1.6 0.064 13.2 1.1 2.4 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 KPI44003.1 - 0.00014 21.3 0.4 0.0003 20.2 0.3 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 KPI44003.1 - 0.0072 16.3 0.1 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KPI44003.1 - 0.0087 16.3 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KPI44003.1 - 0.013 16.2 0.0 0.027 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KPI44003.1 - 0.021 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 KPI44003.1 - 0.023 13.9 0.5 0.1 11.7 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 KPI44003.1 - 0.032 13.8 0.1 0.066 12.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 KPI44003.1 - 0.07 12.5 0.1 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KPI44003.1 - 0.071 13.2 0.0 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KPI44003.1 - 0.072 13.0 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 KPI44003.1 - 0.091 12.3 0.2 0.23 10.9 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 KPI44003.1 - 0.14 11.6 0.4 0.29 10.6 0.3 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 KPI44003.1 - 0.15 11.0 0.2 0.33 9.9 0.1 1.4 1 0 0 1 1 1 0 Septin AAA_16 PF13191.1 KPI44003.1 - 0.16 11.9 1.9 0.27 11.2 0.3 2.1 2 1 0 2 2 2 0 AAA ATPase domain PRK PF00485.13 KPI44003.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family T2SE PF00437.15 KPI44003.1 - 0.23 10.3 0.1 0.44 9.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Dynamin_N PF00350.18 KPI44003.1 - 1.7 8.4 3.0 1.2 8.8 0.1 2.2 3 0 0 3 3 3 0 Dynamin family TPP_enzyme_N PF02776.13 KPI44004.1 - 3.5e-37 127.5 0.0 7.2e-37 126.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KPI44004.1 - 8.2e-18 64.4 0.0 2.2e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KPI44004.1 - 1.3e-17 63.8 0.0 2.5e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Sulfate_transp PF00916.15 KPI44005.1 - 1.4e-31 109.5 1.9 2.6e-31 108.6 1.3 1.3 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 KPI44005.1 - 7.2e-14 51.3 0.0 1.4e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 KPI44005.1 - 8.5e-12 44.5 0.0 1.6e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain adh_short PF00106.20 KPI44006.1 - 5.7e-26 91.4 0.0 9.3e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI44006.1 - 1.7e-12 47.3 0.0 2.8e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI44006.1 - 2.3e-09 37.3 0.0 2.9e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KPI44006.1 - 0.0084 15.5 0.2 0.044 13.2 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI44006.1 - 0.11 11.1 0.1 0.99 8.0 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Romo1 PF10247.4 KPI44007.1 - 1.6e-25 89.0 14.8 1.9e-25 88.8 10.3 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_OmpA PF13436.1 KPI44007.1 - 0.24 11.0 3.6 0.51 10.0 2.5 1.6 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Tim17 PF02466.14 KPI44007.1 - 2.1 8.3 11.7 4.7 7.2 1.4 2.1 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Amidohydro_1 PF01979.15 KPI44008.1 - 4.5e-14 52.8 1.6 1.3e-13 51.3 1.1 1.8 1 1 0 1 1 1 1 Amidohydrolase family FAA_hydrolase PF01557.13 KPI44008.1 - 8.2e-12 45.0 0.0 1.4e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Amidohydro_5 PF13594.1 KPI44008.1 - 3.5e-08 33.1 0.0 1.8e-07 30.8 0.0 2.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KPI44008.1 - 1.6e-07 31.6 1.6 2.6e-05 24.4 1.1 2.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KPI44008.1 - 0.0032 16.7 4.0 0.0098 15.1 1.8 2.7 1 1 0 1 1 1 1 Amidohydrolase family KH_2 PF07650.12 KPI44008.1 - 0.11 12.0 0.0 0.49 9.9 0.0 2.1 2 0 0 2 2 2 0 KH domain Sugar_tr PF00083.19 KPI44009.1 - 1.2e-78 264.6 22.1 1.5e-78 264.4 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI44009.1 - 1.7e-22 79.6 28.4 3.5e-21 75.3 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NfeD PF01957.13 KPI44009.1 - 0.16 12.0 4.5 3.9 7.5 0.2 3.4 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding DUF899 PF05988.7 KPI44010.1 - 7.6e-61 205.2 0.0 1.2e-60 204.5 0.0 1.3 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF899) EssA PF10661.4 KPI44011.1 - 0.045 13.4 0.1 0.06 13.0 0.1 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Ferritin_2 PF13668.1 KPI44012.1 - 6.7e-07 29.3 0.3 1.2e-06 28.5 0.2 1.5 1 0 0 1 1 1 1 Ferritin-like domain RGS PF00615.14 KPI44013.1 - 4.9e-29 100.8 0.1 1.6e-28 99.1 0.0 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 KPI44013.1 - 3.2e-20 71.6 0.0 6.1e-16 57.9 0.0 3.1 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Replic_Relax PF13814.1 KPI44013.1 - 0.051 13.4 0.2 2.9 7.6 0.0 3.0 3 1 1 4 4 4 0 Replication-relaxation DNA_photolyase PF00875.13 KPI44013.1 - 0.06 13.0 0.1 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 DNA photolyase MFS_1 PF07690.11 KPI44014.1 - 1.4e-34 119.3 25.4 2.1e-34 118.8 17.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KPI44014.1 - 6.9e-05 22.3 0.9 0.00022 20.7 0.6 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.2 KPI44014.1 - 0.082 12.7 2.3 0.34 10.7 1.6 2.2 1 0 0 1 1 1 0 MFS_1 like family Ribosomal_S4e PF00900.15 KPI44015.1 - 1e-30 105.2 0.2 1.9e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KPI44015.1 - 3.8e-16 58.6 4.4 8.9e-16 57.4 3.1 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 KPI44015.1 - 1.1e-06 28.0 0.0 2.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KPI44015.1 - 0.00087 18.9 3.9 0.00087 18.9 2.7 2.4 3 0 0 3 3 3 1 KOW motif Transket_pyr PF02779.19 KPI44016.1 - 5.2e-64 215.0 0.0 8.4e-64 214.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KPI44016.1 - 4.6e-55 186.4 0.0 6.8e-55 185.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Glyco_hydro_17 PF00332.13 KPI44016.1 - 0.093 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 DUF4544 PF15077.1 KPI44017.1 - 0.44 10.0 4.6 0.13 11.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4544) PSK PF06404.7 KPI44017.1 - 2 9.2 5.3 0.49 11.1 0.4 2.4 2 1 0 2 2 2 0 Phytosulfokine precursor protein (PSK) UCR_14kD PF02271.11 KPI44018.1 - 1.4e-45 153.3 0.3 1.6e-45 153.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Semialdhyde_dhC PF02774.13 KPI44019.1 - 3.1e-35 121.7 0.0 4.8e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KPI44019.1 - 1.7e-28 99.3 0.0 5.1e-28 97.8 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KPI44019.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 KPI44019.1 - 0.049 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase bZIP_1 PF00170.16 KPI44020.1 - 0.0029 17.5 14.0 0.0064 16.4 9.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KPI44020.1 - 0.014 15.2 19.7 0.12 12.1 13.7 2.1 1 1 0 1 1 1 0 Basic region leucine zipper Gastrin PF00918.12 KPI44020.1 - 0.27 12.0 3.2 1.7 9.4 0.1 2.3 2 0 0 2 2 2 0 Gastrin/cholecystokinin family bZIP_Maf PF03131.12 KPI44020.1 - 2.2 8.6 15.1 0.15 12.3 6.8 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor zf-C2H2 PF00096.21 KPI44021.1 - 0.00017 21.7 5.0 0.062 13.6 0.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI44021.1 - 0.003 17.7 8.3 0.21 11.9 0.5 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger Sina PF03145.11 KPI44021.1 - 0.014 15.0 2.4 0.021 14.4 1.7 1.2 1 0 0 1 1 1 0 Seven in absentia protein family DUF2986 PF11661.3 KPI44021.1 - 0.24 11.7 0.1 0.24 11.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) AAA_16 PF13191.1 KPI44022.1 - 9.7e-21 74.5 0.8 3.9e-20 72.6 0.6 2.0 1 0 0 1 1 1 1 AAA ATPase domain ORC4_C PF14629.1 KPI44022.1 - 2.5e-11 43.3 0.0 6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_22 PF13401.1 KPI44022.1 - 2.2e-07 31.0 0.0 9.6e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KPI44022.1 - 5.8e-06 26.1 0.0 2.2e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 KPI44022.1 - 0.00012 21.7 0.1 0.00038 20.1 0.1 1.9 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 KPI44022.1 - 0.00045 19.3 0.2 0.0053 15.8 0.0 2.1 2 0 0 2 2 2 1 KAP family P-loop domain AAA_33 PF13671.1 KPI44022.1 - 0.0013 18.5 2.1 0.049 13.4 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA PF00004.24 KPI44022.1 - 0.0013 18.8 0.0 0.0084 16.3 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KPI44022.1 - 0.0056 16.1 0.1 1.1 8.6 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_14 PF13173.1 KPI44022.1 - 0.013 15.4 0.0 0.043 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KPI44022.1 - 0.016 14.1 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 KPI44022.1 - 0.037 13.4 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.16 KPI44022.1 - 0.043 12.9 0.0 0.11 11.6 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KPI44022.1 - 0.061 13.0 0.2 0.26 10.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DAP3 PF10236.4 KPI44022.1 - 0.063 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF815 PF05673.8 KPI44022.1 - 0.065 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PIF1 PF05970.9 KPI44022.1 - 0.26 10.1 0.0 0.49 9.2 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase NB-ARC PF00931.17 KPI44022.1 - 0.28 9.9 0.6 0.43 9.3 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.1 KPI44022.1 - 0.35 10.6 3.6 0.83 9.4 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain DDRGK PF09756.4 KPI44022.1 - 9.6 5.5 8.4 0.52 9.7 1.6 1.8 2 0 0 2 2 2 0 DDRGK domain Amidase PF01425.16 KPI44023.1 - 2e-108 363.1 0.3 2e-106 356.4 0.2 2.0 1 1 0 1 1 1 1 Amidase T2SE_Nter PF05157.10 KPI44023.1 - 0.051 13.6 0.1 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain ABC2_membrane PF01061.19 KPI44025.1 - 6.8e-29 100.5 26.8 9.9e-29 99.9 18.6 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KPI44025.1 - 1.6e-26 93.2 0.2 7.6e-26 91.0 0.1 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KPI44025.1 - 2.6e-09 37.4 0.6 0.00027 20.9 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KPI44025.1 - 8.4e-07 29.1 1.6 1.4e-06 28.4 0.4 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KPI44025.1 - 1.8e-06 27.4 0.1 2.5e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KPI44025.1 - 6.5e-06 25.5 0.1 2.8e-05 23.4 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KPI44025.1 - 9.6e-05 21.6 0.1 0.00016 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 KPI44025.1 - 0.00017 20.7 12.1 0.00039 19.5 8.4 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.1 KPI44025.1 - 0.00021 20.7 0.1 0.00046 19.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 KPI44025.1 - 0.00023 21.1 0.0 0.00049 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KPI44025.1 - 0.00037 20.1 0.1 0.00091 18.9 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 KPI44025.1 - 0.00042 20.5 0.0 0.043 14.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KPI44025.1 - 0.00058 19.3 0.1 0.0025 17.2 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein cobW PF02492.14 KPI44025.1 - 0.00073 19.0 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KPI44025.1 - 0.00079 20.2 0.0 0.0021 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KPI44025.1 - 0.00086 18.8 0.0 0.0031 16.9 0.0 1.8 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 KPI44025.1 - 0.00087 19.4 0.0 0.0042 17.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KPI44025.1 - 0.0012 18.7 1.3 0.0013 18.5 0.1 1.7 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.10 KPI44025.1 - 0.0014 18.4 0.0 0.0083 15.8 0.0 2.0 2 0 0 2 2 2 1 NTPase T2SE PF00437.15 KPI44025.1 - 0.0023 16.8 0.0 0.0041 16.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein NACHT PF05729.7 KPI44025.1 - 0.0032 17.1 0.0 0.0065 16.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain SRP54 PF00448.17 KPI44025.1 - 0.0041 16.5 0.0 0.0085 15.5 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_18 PF13238.1 KPI44025.1 - 0.0042 17.3 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KPI44025.1 - 0.005 16.4 0.6 0.0094 15.5 0.4 1.6 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 KPI44025.1 - 0.007 15.9 0.5 0.016 14.7 0.1 1.8 2 0 0 2 2 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_15 PF13175.1 KPI44025.1 - 0.0071 15.4 0.0 1 8.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 KPI44025.1 - 0.0093 15.8 0.0 0.034 14.0 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 KPI44025.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 KPI44025.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 KPI44025.1 - 0.022 14.4 0.0 0.09 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KPI44025.1 - 0.04 14.0 0.0 0.099 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.15 KPI44025.1 - 0.044 13.4 0.3 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_14 PF13173.1 KPI44025.1 - 0.054 13.3 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.1 KPI44025.1 - 0.068 13.4 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 KPI44025.1 - 0.073 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.4 KPI44025.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 KPI44025.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_PrkA PF08298.6 KPI44025.1 - 0.17 10.5 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Abhydrolase_3 PF07859.8 KPI44026.1 - 5.1e-32 111.1 0.5 1.2e-29 103.4 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI44026.1 - 0.007 16.1 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ala_racemase_C PF00842.16 KPI44026.1 - 0.027 13.8 0.0 0.93 8.9 0.0 2.2 1 1 1 2 2 2 0 Alanine racemase, C-terminal domain Lactamase_B_2 PF12706.2 KPI44027.1 - 8.7e-29 100.4 0.1 1.7e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KPI44027.1 - 4.4e-22 77.3 0.0 1e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease HSP70 PF00012.15 KPI44029.1 - 3.3e-80 269.7 3.1 9.4e-80 268.2 0.5 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KPI44029.1 - 4.4e-05 22.2 0.0 7.6e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.3 KPI44029.1 - 0.00081 18.3 0.1 0.25 10.1 0.0 2.3 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; DUF4632 PF15451.1 KPI44029.1 - 0.091 12.6 1.8 0.22 11.4 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) PBP1_TM PF14812.1 KPI44029.1 - 0.59 10.4 3.9 1.3 9.3 2.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 KPI44029.1 - 1.1 8.8 5.5 2.4 7.7 2.7 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Pap_E4 PF02711.9 KPI44029.1 - 9.9 7.0 8.9 0.56 11.0 0.4 3.0 3 0 0 3 3 3 0 E4 protein His_Phos_2 PF00328.17 KPI44030.1 - 8e-34 117.4 0.0 1.1e-33 117.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HATPase_c PF02518.21 KPI44031.1 - 3e-21 75.1 0.1 9.2e-21 73.6 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KPI44031.1 - 2.5e-14 53.2 0.0 6.5e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KPI44031.1 - 8.8e-13 48.0 0.0 2.4e-12 46.6 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 KPI44031.1 - 9.4e-08 32.3 0.1 7.5e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.1 KPI44031.1 - 0.00036 20.6 0.1 0.0094 16.0 0.0 3.0 3 0 0 3 3 3 1 GAF domain HATPase_c_3 PF13589.1 KPI44031.1 - 0.016 14.9 0.1 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase STIL_N PF15253.1 KPI44031.1 - 0.018 13.7 0.8 0.035 12.8 0.6 1.4 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus bZIP_2 PF07716.10 KPI44032.1 - 3e-07 30.1 8.9 4.9e-07 29.4 6.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KPI44032.1 - 1.9e-05 24.4 6.8 3.2e-05 23.8 4.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor Filament_head PF04732.9 KPI44032.1 - 0.034 14.8 0.3 0.034 14.8 0.2 2.6 2 1 1 3 3 3 0 Intermediate filament head (DNA binding) region bZIP_Maf PF03131.12 KPI44032.1 - 0.041 14.1 2.1 0.085 13.1 1.5 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor SUFU_C PF12470.3 KPI44032.1 - 0.15 11.6 0.4 0.31 10.6 0.3 1.4 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain adh_short PF00106.20 KPI44033.1 - 2.2e-16 60.2 0.0 3.1e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI44033.1 - 5.2e-08 32.9 0.0 2e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI44033.1 - 1.5e-07 31.2 0.0 1.9e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI44033.1 - 0.0068 15.8 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_trans_4_3 PF12000.3 KPI44033.1 - 0.053 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Gkycosyl transferase family 4 group DNA_pol_phi PF04931.8 KPI44034.1 - 9.6e-48 162.5 22.6 1.7e-32 112.1 17.1 3.3 2 2 0 2 2 2 2 DNA polymerase phi DUF1669 PF07894.7 KPI44034.1 - 0.045 12.9 1.4 0.13 11.4 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1669) EntA_Immun PF08951.5 KPI44034.1 - 0.24 11.6 2.6 3.7 7.7 0.0 3.4 4 0 0 4 4 4 0 Enterocin A Immunity BUD22 PF09073.5 KPI44034.1 - 0.74 8.8 27.1 1.8 7.5 18.6 1.7 1 1 0 1 1 1 0 BUD22 SIP1 PF04938.7 KPI44035.1 - 0.013 14.8 0.4 0.014 14.7 0.3 1.1 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF2418 PF10332.4 KPI44036.1 - 3.9e-31 107.3 0.4 7.6e-31 106.3 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) GDC-P PF02347.11 KPI44037.1 - 8.5e-177 588.1 0.0 1.2e-162 541.5 0.0 2.3 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KPI44037.1 - 1.3e-08 34.3 0.0 3.3e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase UNC-93 PF05978.11 KPI44038.1 - 1.3e-09 37.7 3.3 3.3e-09 36.4 2.3 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KPI44038.1 - 3e-08 32.7 25.3 9.8e-07 27.7 17.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Choline_kinase PF01633.15 KPI44039.1 - 3.3e-46 157.5 0.0 1.5e-43 148.8 0.0 2.1 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.18 KPI44039.1 - 6.1e-11 42.5 0.0 3.3e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KPI44039.1 - 0.00011 21.4 0.0 0.00023 20.4 0.0 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 KPI44039.1 - 0.06 11.9 0.0 0.075 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Fungal_trans PF04082.13 KPI44040.1 - 3.4e-09 35.9 0.2 6.1e-09 35.1 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain TruD PF01142.13 KPI44041.1 - 8.7e-53 179.3 0.0 3.2e-50 170.8 0.0 3.6 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) GFO_IDH_MocA PF01408.17 KPI44042.1 - 1.4e-07 32.0 0.1 4.7e-07 30.3 0.1 2.0 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_transf_3 PF02515.12 KPI44043.1 - 2.1e-22 79.3 0.0 3.5e-17 62.2 0.1 3.3 2 1 0 2 2 2 2 CoA-transferase family III Aldedh PF00171.17 KPI44044.1 - 2.9e-12 45.6 0.1 1.1e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 KPI44044.1 - 0.0038 16.0 0.2 0.032 12.9 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Fungal_trans_2 PF11951.3 KPI44045.1 - 0.00031 19.4 3.4 0.00076 18.1 0.4 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain AAA PF00004.24 KPI44046.1 - 8.8e-87 288.0 0.0 2.4e-42 144.2 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KPI44046.1 - 3.9e-14 53.5 0.0 5.3e-09 36.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.7 KPI44046.1 - 2.5e-13 49.6 0.1 1.9e-07 30.3 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KPI44046.1 - 1.3e-12 47.9 0.1 0.00033 20.7 0.0 4.8 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 KPI44046.1 - 1.6e-12 47.7 3.4 8.3e-06 25.9 0.0 4.2 3 2 1 4 4 4 2 AAA ATPase domain AAA_14 PF13173.1 KPI44046.1 - 6.1e-11 42.3 0.0 7.5e-06 25.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KPI44046.1 - 2.6e-10 39.8 1.4 0.00012 21.7 0.1 3.9 2 2 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 KPI44046.1 - 2.9e-10 40.1 0.0 0.00012 22.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KPI44046.1 - 3.5e-09 36.5 0.2 0.0065 16.2 0.0 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KPI44046.1 - 3.8e-09 36.1 0.0 0.00091 18.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_2 PF07724.9 KPI44046.1 - 7.3e-09 35.7 0.0 0.006 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 KPI44046.1 - 1.3e-08 34.1 0.1 0.0015 17.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 KPI44046.1 - 2.7e-08 34.1 0.0 0.00055 20.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KPI44046.1 - 3.2e-08 33.2 1.8 0.61 9.4 0.0 4.7 2 2 0 4 4 4 3 AAA domain AAA_28 PF13521.1 KPI44046.1 - 5.1e-08 33.0 0.0 0.0022 17.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 KPI44046.1 - 7.3e-08 32.8 0.0 0.02 15.1 0.0 3.0 2 0 0 2 2 2 2 ABC transporter TIP49 PF06068.8 KPI44046.1 - 2.3e-07 29.8 0.2 0.0005 18.9 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 KPI44046.1 - 2.4e-07 30.9 0.0 0.018 15.1 0.0 3.1 3 0 0 3 3 3 2 RNA helicase NACHT PF05729.7 KPI44046.1 - 4.9e-07 29.5 0.1 0.11 12.1 0.1 4.2 2 2 1 3 3 3 2 NACHT domain Mg_chelatase PF01078.16 KPI44046.1 - 5.6e-06 25.6 0.7 0.065 12.3 0.0 3.1 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.1 KPI44046.1 - 6.2e-06 26.2 0.0 0.00017 21.5 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family ATP-synt_ab PF00006.20 KPI44046.1 - 7.6e-06 25.5 0.0 0.14 11.6 0.0 3.1 3 0 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.21 KPI44046.1 - 8.6e-06 25.3 0.1 0.26 10.7 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.6 KPI44046.1 - 9e-06 25.3 0.0 0.025 14.1 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KPI44046.1 - 9.2e-06 25.3 0.0 0.025 14.1 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 KPI44046.1 - 1.9e-05 24.3 0.1 0.029 13.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.10 KPI44046.1 - 3e-05 22.9 0.0 0.0029 16.3 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 KPI44046.1 - 3.3e-05 22.8 0.0 0.044 12.6 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain SKI PF01202.17 KPI44046.1 - 5.7e-05 23.0 0.0 0.085 12.7 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase Parvo_NS1 PF01057.12 KPI44046.1 - 6.3e-05 21.9 0.2 0.27 10.0 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 KPI44046.1 - 0.00011 22.2 0.0 0.26 11.3 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 KPI44046.1 - 0.00033 20.4 0.0 1.3 8.7 0.0 3.1 2 2 0 2 2 2 2 Archaeal ATPase PhoH PF02562.11 KPI44046.1 - 0.00036 19.8 0.5 0.66 9.1 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ADK PF00406.17 KPI44046.1 - 0.00071 19.4 0.1 0.14 12.0 0.0 2.9 3 0 0 3 3 2 1 Adenylate kinase UPF0079 PF02367.12 KPI44046.1 - 0.00073 19.1 0.1 1.4 8.6 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 KPI44046.1 - 0.0023 17.4 0.1 0.53 9.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.1 KPI44046.1 - 0.0024 17.5 0.0 2.9 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KPI44046.1 - 0.0025 18.1 6.3 0.031 14.5 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.1 KPI44046.1 - 0.0026 17.3 0.2 2.3 7.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.10 KPI44046.1 - 0.0027 17.4 0.0 0.84 9.3 0.0 2.8 2 0 0 2 2 2 1 NTPase KaiC PF06745.8 KPI44046.1 - 0.0033 16.5 0.3 1.6 7.7 0.0 3.0 2 1 0 3 3 3 1 KaiC MMR_HSR1 PF01926.18 KPI44046.1 - 0.0039 17.1 0.0 2.9 7.8 0.0 3.4 2 2 1 3 3 3 0 50S ribosome-binding GTPase CPT PF07931.7 KPI44046.1 - 0.0056 16.3 0.0 0.46 10.0 0.0 2.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein T2SE PF00437.15 KPI44046.1 - 0.013 14.4 0.1 0.14 11.0 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.4 KPI44046.1 - 0.015 14.2 0.0 0.74 8.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DAP3 PF10236.4 KPI44046.1 - 0.016 14.1 0.0 3.1 6.6 0.0 2.8 2 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ResIII PF04851.10 KPI44046.1 - 0.017 14.9 0.0 1.9 8.2 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.4 KPI44046.1 - 0.026 14.0 0.0 15 5.0 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.13 KPI44046.1 - 0.026 14.1 0.1 8.4 5.9 0.0 3.0 3 1 0 3 3 2 0 Bacterial dnaA protein KTI12 PF08433.5 KPI44046.1 - 0.027 13.6 0.2 13 4.9 0.0 3.4 3 0 0 3 3 3 0 Chromatin associated protein KTI12 DUF815 PF05673.8 KPI44046.1 - 0.027 13.3 0.0 2.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.14 KPI44046.1 - 0.038 13.4 0.1 12 5.3 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 KPI44046.1 - 0.045 13.1 6.4 3.9 6.8 0.0 3.8 4 1 0 4 4 4 0 AAA-like domain DUF258 PF03193.11 KPI44046.1 - 0.14 11.3 0.1 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_13 PF13166.1 KPI44046.1 - 0.57 8.5 1.9 20 3.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain Fungal_trans_2 PF11951.3 KPI44047.1 - 8.9e-14 50.8 1.3 2.7e-13 49.2 0.9 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2374 PF09574.5 KPI44047.1 - 0.089 12.4 0.4 1.2 8.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) BRCT PF00533.21 KPI44048.1 - 5.9e-36 122.4 0.0 6.4e-10 39.0 0.1 6.6 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KPI44048.1 - 2.3e-35 120.2 1.7 1.5e-19 69.5 0.4 5.2 5 0 0 5 5 5 4 twin BRCT domain DUF1675 PF07897.6 KPI44048.1 - 0.057 13.2 3.8 0.11 12.3 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) TIM PF00121.13 KPI44049.1 - 3.7e-22 78.5 0.0 2.1e-21 76.0 0.0 2.1 2 1 0 2 2 2 1 Triosephosphate isomerase bZIP_1 PF00170.16 KPI44050.1 - 1.2e-07 31.6 12.1 2e-07 30.8 8.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KPI44050.1 - 0.0042 16.8 17.6 0.0059 16.3 11.9 1.6 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KPI44050.1 - 0.015 15.5 12.6 0.029 14.6 8.7 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor 7TMR-HDED PF07697.6 KPI44050.1 - 0.12 12.0 9.0 0.062 13.0 4.7 1.7 3 0 0 3 3 3 0 7TM-HD extracellular SecA_DEAD PF07517.9 KPI44050.1 - 0.47 9.6 3.6 0.63 9.2 2.5 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain DUF972 PF06156.8 KPI44050.1 - 0.75 10.1 4.7 1.4 9.3 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) PQ-loop PF04193.9 KPI44051.1 - 9.4e-38 127.5 14.7 3.2e-20 71.4 0.3 2.7 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 KPI44051.1 - 0.033 14.0 1.0 0.22 11.4 0.0 2.4 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Peptidase_M3 PF01432.15 KPI44052.1 - 8.3e-160 532.7 0.1 1.1e-159 532.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 DUF1275 PF06912.6 KPI44053.1 - 5.6e-35 120.4 12.1 8e-35 119.9 8.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Glycos_transf_4 PF00953.16 KPI44053.1 - 0.026 14.3 0.2 0.026 14.3 0.1 2.0 3 0 0 3 3 3 0 Glycosyl transferase family 4 DUF4094 PF13334.1 KPI44053.1 - 7.1 7.0 7.1 4 7.8 0.3 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4094) adh_short PF00106.20 KPI44054.1 - 2.8e-21 76.1 2.3 4.2e-21 75.5 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI44054.1 - 5.9e-16 58.9 0.0 1.3e-09 38.1 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI44054.1 - 0.00018 21.2 1.0 0.00027 20.6 0.7 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KPI44054.1 - 0.0024 17.5 0.8 0.024 14.2 0.1 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PMP1_2 PF08114.6 KPI44055.1 - 2.3 7.7 5.9 0.25 10.8 0.6 2.0 2 0 0 2 2 2 0 ATPase proteolipid family Pilus_CpaD PF09476.5 KPI44056.1 - 0.04 13.3 0.1 0.054 12.9 0.1 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) DUF2574 PF10836.3 KPI44056.1 - 0.58 9.8 8.0 0.25 11.0 3.2 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2574) Med16 PF11635.3 KPI44057.1 - 2.6e-25 88.5 0.0 3.4e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Rhodanese PF00581.15 KPI44058.1 - 2.4e-12 47.2 0.0 3.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Glycos_transf_4 PF00953.16 KPI44061.1 - 9.6e-32 109.9 7.5 9.6e-32 109.9 5.2 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 DnaJ PF00226.26 KPI44062.1 - 5.9e-20 70.7 1.1 5.9e-20 70.7 0.8 2.5 2 1 0 2 2 2 1 DnaJ domain HAD PF12710.2 KPI44063.1 - 4.3e-16 59.6 0.0 6.3e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KPI44063.1 - 1.4e-13 51.7 0.0 2.4e-12 47.7 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KPI44063.1 - 1.3e-11 44.6 0.0 5.5e-10 39.2 0.1 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KPI44063.1 - 1.3e-05 24.5 0.0 0.00012 21.2 0.0 2.0 1 1 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.1 KPI44063.1 - 0.00081 19.6 0.0 0.011 16.0 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 KPI44063.1 - 0.03 13.3 0.0 0.046 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) DUF4287 PF14117.1 KPI44063.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) ADH_zinc_N PF00107.21 KPI44064.1 - 3.7e-10 39.4 0.0 6.8e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI44064.1 - 2.4e-06 27.2 0.0 2.7e-05 23.8 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Beta-lactamase PF00144.19 KPI44065.1 - 3.5e-42 144.5 0.2 5.4e-42 143.9 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KPI44065.1 - 0.014 14.7 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase FMN_dh PF01070.13 KPI44066.1 - 9.3e-106 353.6 0.0 1.1e-105 353.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KPI44066.1 - 0.00011 21.2 0.1 0.00016 20.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KPI44066.1 - 0.00015 20.8 0.8 0.00023 20.1 0.5 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KPI44066.1 - 0.00061 19.1 0.7 0.064 12.5 0.0 2.2 1 1 1 2 2 2 2 Histidine biosynthesis protein NMO PF03060.10 KPI44066.1 - 0.012 14.7 1.5 0.02 14.0 1.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.9 KPI44066.1 - 0.029 13.4 1.5 5 6.1 0.1 2.7 2 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 KPI44066.1 - 0.092 11.6 0.1 0.34 9.8 0.0 1.8 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase IGPS PF00218.16 KPI44066.1 - 0.14 11.2 0.3 1.7 7.6 0.2 2.1 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase Sugar_tr PF00083.19 KPI44067.1 - 2e-73 247.5 23.3 2.5e-73 247.1 16.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI44067.1 - 3.1e-08 32.7 37.2 3.1e-08 32.7 25.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI44067.1 - 7.5e-05 21.2 22.5 8.1e-05 21.1 4.5 3.0 2 1 1 3 3 3 3 MFS/sugar transport protein DUF619 PF04768.8 KPI44068.1 - 2.6e-48 163.6 0.0 1.8e-46 157.6 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF619) Spc97_Spc98 PF04130.8 KPI44069.1 - 8.1e-105 351.1 0.6 6.1e-74 249.2 0.3 2.8 2 1 1 3 3 3 2 Spc97 / Spc98 family Trans_reg_C PF00486.23 KPI44069.1 - 0.044 13.7 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Coq4 PF05019.8 KPI44070.1 - 1.1e-97 325.3 0.0 1.4e-97 325.0 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 MFS_1 PF07690.11 KPI44071.1 - 2.7e-31 108.5 26.8 2.7e-31 108.5 18.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1049 PF06305.6 KPI44071.1 - 3.3 7.2 6.6 2.5 7.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) FAD_binding_2 PF00890.19 KPI44072.1 - 1.9e-36 125.8 0.0 3e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain 2OG-FeII_Oxy_2 PF13532.1 KPI44072.1 - 3.7e-11 43.2 0.1 9.2e-11 41.9 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pyr_redox_2 PF07992.9 KPI44072.1 - 0.0064 16.3 0.0 0.098 12.5 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4055 PF13264.1 KPI44072.1 - 0.19 11.8 1.1 0.39 10.7 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) SNARE PF05739.14 KPI44073.1 - 5.4e-17 61.2 1.9 5.4e-17 61.2 1.3 3.0 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KPI44073.1 - 1.9e-13 50.4 1.2 1.9e-13 50.4 0.8 2.5 3 0 0 3 3 3 1 Syntaxin MCPsignal PF00015.16 KPI44073.1 - 0.0062 16.1 5.5 0.048 13.1 0.1 2.2 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Reo_sigmaC PF04582.7 KPI44073.1 - 0.036 13.2 1.0 0.29 10.2 0.8 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 KPI44073.1 - 0.05 12.2 5.1 0.031 12.9 1.4 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Syntaxin-18_N PF10496.4 KPI44073.1 - 0.1 12.4 3.7 0.38 10.6 0.0 3.0 3 1 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus NPV_P10 PF05531.7 KPI44073.1 - 0.22 11.7 7.3 5.1 7.4 0.2 3.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 KPI44073.1 - 0.4 10.2 8.8 4.4 6.8 0.1 2.4 2 1 0 2 2 2 0 IncA protein SF-assemblin PF06705.6 KPI44073.1 - 0.52 9.4 8.2 5 6.1 0.1 3.0 2 1 1 3 3 3 0 SF-assemblin/beta giardin Synaptobrevin PF00957.16 KPI44073.1 - 1.5 8.4 4.3 2.5 7.7 0.1 3.1 3 0 0 3 3 3 0 Synaptobrevin BCNT PF07572.7 KPI44074.1 - 1.3e-22 79.5 1.6 8.4e-22 76.9 0.3 2.5 2 0 0 2 2 2 1 Bucentaur or craniofacial development Amidohydro_2 PF04909.9 KPI44075.1 - 7e-27 94.6 0.0 9e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase BTB PF00651.26 KPI44076.1 - 8.2e-10 38.6 0.0 3.3e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain Syntaxin_2 PF14523.1 KPI44077.1 - 7e-25 87.0 2.4 7e-25 87.0 1.7 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KPI44077.1 - 2.4e-19 68.7 2.0 7.3e-19 67.2 1.4 1.9 1 0 0 1 1 1 1 SNARE domain DUF883 PF05957.8 KPI44077.1 - 0.35 11.2 0.1 0.35 11.2 0.1 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Synaptobrevin PF00957.16 KPI44077.1 - 0.48 10.0 2.7 0.87 9.2 1.3 2.0 2 1 0 2 2 2 0 Synaptobrevin adh_short PF00106.20 KPI44079.1 - 2.1e-32 112.3 0.1 2.6e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI44079.1 - 4.8e-18 65.8 0.0 6e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI44079.1 - 6.6e-13 48.7 0.3 1e-12 48.0 0.0 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KPI44079.1 - 8.2e-05 22.1 0.1 0.00013 21.4 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KPI44079.1 - 0.0044 16.7 0.1 0.0083 15.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KPI44079.1 - 0.0052 16.0 0.4 0.008 15.4 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI44079.1 - 0.0057 16.6 0.5 0.11 12.4 0.4 2.3 1 1 0 1 1 1 1 NADH(P)-binding Glyco_transf_5 PF08323.6 KPI44079.1 - 0.0073 15.8 0.0 0.35 10.3 0.0 2.3 2 1 0 2 2 2 1 Starch synthase catalytic domain THF_DHG_CYH_C PF02882.14 KPI44079.1 - 0.02 13.9 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.12 KPI44079.1 - 0.048 12.5 0.7 0.19 10.5 0.2 2.1 2 1 0 2 2 2 0 RmlD substrate binding domain ADH_zinc_N PF00107.21 KPI44079.1 - 0.069 12.7 0.2 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ApbA PF02558.11 KPI44079.1 - 0.07 12.5 0.1 0.23 10.9 0.0 1.8 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 KPI44079.1 - 0.094 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_nitro PF00148.14 KPI44079.1 - 0.098 11.2 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase F420_oxidored PF03807.12 KPI44079.1 - 0.11 12.8 0.9 0.71 10.3 0.2 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KPI44079.1 - 0.22 11.1 0.7 0.4 10.3 0.2 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acyl-CoA_dh_1 PF00441.19 KPI44080.1 - 3.2e-17 63.0 0.2 2.4e-15 56.9 0.1 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KPI44080.1 - 1.2e-08 34.2 0.7 7.8e-08 31.7 0.5 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain P12 PF12669.2 KPI44082.1 - 8.6 6.6 12.0 8e+02 0.3 8.4 2.3 1 1 0 1 1 1 0 Virus attachment protein p12 family Glyoxalase_4 PF13669.1 KPI44083.1 - 7.3e-21 74.2 0.0 1.5e-20 73.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.14 KPI44084.1 - 3.2e-13 49.4 0.0 2.6e-12 46.5 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI44084.1 - 1.2e-08 34.2 0.6 7e-06 25.1 0.4 2.6 3 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI44084.1 - 9.3e-06 24.7 1.7 1.7e-05 23.8 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KPI44084.1 - 1.2e-05 25.2 0.1 3.3e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KPI44084.1 - 2.1e-05 23.6 0.0 4.3e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KPI44084.1 - 7.1e-05 22.7 0.8 0.00014 21.7 0.6 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI44084.1 - 8.9e-05 22.8 0.3 0.0016 18.8 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI44084.1 - 0.00024 20.8 2.0 0.096 12.4 0.0 2.7 3 1 0 3 3 3 2 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KPI44084.1 - 0.00086 18.0 0.0 0.014 14.0 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 KPI44084.1 - 0.00093 18.3 0.4 0.0013 17.8 0.3 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 KPI44084.1 - 0.0072 15.2 0.9 0.01 14.7 0.6 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 KPI44084.1 - 0.0095 15.5 1.2 0.033 13.8 0.6 2.0 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KPI44084.1 - 0.011 14.2 0.7 0.021 13.3 0.5 1.4 1 0 0 1 1 1 0 HI0933-like protein Amino_oxidase PF01593.19 KPI44084.1 - 0.058 12.4 0.1 2.2 7.2 0.1 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KPI44084.1 - 0.068 13.2 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KPI44084.1 - 0.22 10.5 1.0 0.49 9.4 0.4 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 KPI44084.1 - 0.22 10.8 0.2 0.34 10.2 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Mito_carr PF00153.22 KPI44085.1 - 1.7e-66 219.9 4.5 5.1e-23 80.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Clr5 PF14420.1 KPI44086.1 - 2.6e-14 52.8 1.3 5.4e-14 51.8 0.9 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 KPI44086.1 - 0.1 12.5 0.9 0.43 10.5 0.3 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat AAA_33 PF13671.1 KPI44086.1 - 0.72 9.7 5.3 0.34 10.7 1.3 2.1 2 1 0 2 2 2 0 AAA domain Actin PF00022.14 KPI44088.1 - 1.9e-18 66.1 0.0 4.3e-17 61.6 0.0 2.6 2 1 0 2 2 2 1 Actin BRO1 PF03097.13 KPI44089.1 - 4.8e-112 374.4 1.5 4.8e-112 374.4 1.0 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KPI44089.1 - 2.4e-72 243.3 17.2 2.4e-72 243.3 11.9 2.1 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV DUF2237 PF09996.4 KPI44090.1 - 2.6e-31 107.5 0.2 5e-31 106.5 0.2 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) p450 PF00067.17 KPI44091.1 - 1e-68 231.9 0.0 1.3e-68 231.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Spp-24 PF07448.6 KPI44092.1 - 0.039 13.8 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 Secreted phosphoprotein 24 (Spp-24) Cu-oxidase_3 PF07732.10 KPI44094.1 - 1.7e-40 137.4 1.0 2.2e-38 130.6 0.0 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KPI44094.1 - 1.1e-25 89.7 7.9 1.6e-18 66.5 0.1 4.1 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 KPI44094.1 - 4.3e-16 59.2 0.0 3.9e-14 52.8 0.0 3.1 3 1 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.1 KPI44094.1 - 0.013 15.3 0.0 3.6 7.5 0.0 3.9 3 1 1 4 4 4 0 Cupredoxin-like domain DNA_ligase_OB PF03120.11 KPI44094.1 - 0.15 11.7 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain Sugar_tr PF00083.19 KPI44096.1 - 4.3e-46 157.4 7.3 5.5e-46 157.0 5.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI44096.1 - 2.6e-14 52.7 20.6 5.1e-14 51.7 14.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KPI44096.1 - 1.3e-05 23.8 7.6 0.00026 19.5 1.1 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 KPI44096.1 - 0.081 11.0 4.7 0.054 11.6 1.8 1.7 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) CDK2AP PF09806.4 KPI44097.1 - 8.3 6.5 15.5 0.69 10.1 5.8 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein SMC_N PF02463.14 KPI44098.1 - 9e-68 227.7 9.6 1.1e-66 224.2 6.7 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KPI44098.1 - 6.4e-22 77.7 3.6 5.7e-21 74.6 0.1 3.2 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KPI44098.1 - 6.6e-13 49.2 1.4 3.7e-05 23.8 0.1 3.1 3 0 0 3 3 3 2 AAA domain GAS PF13851.1 KPI44098.1 - 0.00017 20.8 6.4 0.00017 20.8 4.4 7.3 3 2 4 7 7 7 2 Growth-arrest specific micro-tubule binding AAA_29 PF13555.1 KPI44098.1 - 0.0004 19.8 0.0 0.0009 18.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.2 KPI44098.1 - 0.0021 17.4 17.6 0.0021 17.4 12.2 6.4 3 2 3 7 7 7 3 Mechanosensitive ion channel porin domain ABC_tran PF00005.22 KPI44098.1 - 0.023 14.9 0.0 0.023 14.9 0.0 5.7 4 2 1 5 5 5 0 ABC transporter Reo_sigmaC PF04582.7 KPI44098.1 - 0.093 11.8 37.0 0.97 8.5 6.9 5.2 3 2 3 6 6 6 0 Reovirus sigma C capsid protein BPL_LplA_LipB PF03099.14 KPI44099.1 - 6.3e-16 58.5 0.0 1.3e-15 57.5 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family p450 PF00067.17 KPI44100.1 - 5.4e-78 262.5 0.0 7.4e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.6 KPI44100.1 - 1.1e-05 24.8 0.0 2.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KPI44100.1 - 0.076 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Cupin PXA PF02194.10 KPI44101.1 - 1.1e-47 162.0 0.5 1.1e-47 162.0 0.4 1.8 2 0 0 2 2 2 1 PXA domain RGS PF00615.14 KPI44101.1 - 1.1e-11 44.8 0.0 3e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain Claudin_2 PF13903.1 KPI44101.1 - 1.2 8.8 3.8 2.3 7.8 2.6 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Pkinase PF00069.20 KPI44103.1 - 1e-07 31.3 0.0 1.2e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KPI44103.1 - 2e-06 27.0 0.0 2.5e-05 23.5 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase p450 PF00067.17 KPI44104.1 - 4.2e-59 200.3 0.0 5.8e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 KPI44105.1 - 4e-24 85.3 0.1 6.3e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI44105.1 - 0.00018 20.5 0.0 0.19 10.5 0.0 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KPI44105.1 - 0.014 14.0 0.2 6.4 5.2 0.0 3.0 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_8 PF13450.1 KPI44105.1 - 0.02 14.9 0.1 0.045 13.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KPI44105.1 - 0.029 14.7 0.1 0.61 10.5 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3295 PF11702.3 KPI44106.1 - 0.085 11.8 6.3 0.11 11.4 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Pal1 PF08316.6 KPI44106.1 - 0.26 11.7 1.9 0.35 11.3 1.3 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein BP28CT PF08146.7 KPI44107.1 - 1.9e-30 105.6 3.3 2.5e-30 105.2 0.3 2.9 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KPI44107.1 - 5e-09 36.1 0.4 5e-09 36.1 0.3 4.3 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 MCPVI PF02993.9 KPI44107.1 - 0.18 11.9 0.1 0.39 10.8 0.1 1.4 1 0 0 1 1 1 0 Minor capsid protein VI Chorismate_synt PF01264.16 KPI44108.1 - 1.9e-131 437.6 0.0 2.2e-131 437.4 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Hormone_4 PF00220.12 KPI44108.1 - 0.062 12.9 3.5 0.16 11.6 2.4 1.8 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain Glyoxalase PF00903.20 KPI44109.1 - 6.8e-10 39.0 1.9 7.2e-09 35.7 0.4 2.3 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KPI44109.1 - 0.00015 22.3 0.5 0.0075 16.8 0.0 2.6 2 1 1 3 3 3 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KPI44109.1 - 0.0031 17.4 0.1 0.019 14.9 0.0 2.3 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1726 PF08351.6 KPI44109.1 - 0.076 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) Fungal_trans PF04082.13 KPI44110.1 - 1.1e-19 70.3 0.0 1.7e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI44110.1 - 0.00028 20.7 10.1 0.00042 20.1 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WH2 PF02205.15 KPI44111.1 - 4.1e-07 29.4 0.7 4.1e-07 29.4 0.5 2.1 2 0 0 2 2 2 1 WH2 motif Abhydrolase_6 PF12697.2 KPI44113.1 - 5.6e-26 91.8 0.1 9.4e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI44113.1 - 7.9e-05 22.4 0.0 0.00019 21.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI44113.1 - 0.0013 18.3 0.0 0.015 14.8 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF1989 PF09347.5 KPI44115.1 - 1.2e-46 158.1 0.2 2.9e-41 140.7 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1989) Rad4 PF03835.10 KPI44116.1 - 1.2e-28 99.3 0.1 1.2e-28 99.3 0.1 2.4 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_2 PF10404.4 KPI44116.1 - 1.3e-16 60.6 0.4 4.8e-15 55.6 0.1 3.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.4 KPI44116.1 - 6.8e-16 57.5 0.0 2.3e-15 55.8 0.0 2.0 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.4 KPI44116.1 - 3.2e-13 49.1 0.0 6.6e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Transglut_core PF01841.14 KPI44116.1 - 0.0012 19.0 0.0 0.0046 17.1 0.0 2.0 1 0 0 1 1 1 1 Transglutaminase-like superfamily HpcH_HpaI PF03328.9 KPI44117.1 - 1.9e-35 121.7 0.0 2.4e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family HECT PF00632.20 KPI44119.1 - 6e-81 272.0 0.1 1.8e-76 257.2 0.0 2.2 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) WW PF00397.21 KPI44119.1 - 1e-32 111.6 17.0 6.7e-11 41.8 1.2 3.9 3 0 0 3 3 3 3 WW domain C2 PF00168.25 KPI44119.1 - 1.3e-16 60.2 0.0 2.9e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain GGDEF PF00990.16 KPI44119.1 - 0.0069 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 GGDEF domain NAD_binding_10 PF13460.1 KPI44120.1 - 1.1e-09 38.5 0.0 1.8e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KPI44120.1 - 0.025 13.5 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase 2-Hacid_dh_C PF02826.14 KPI44120.1 - 0.082 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2231 PF09990.4 KPI44121.1 - 1.5e-05 25.2 0.7 2.2e-05 24.7 0.1 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2231) PEN-2 PF10251.4 KPI44121.1 - 0.0089 16.2 1.2 2.6 8.3 0.0 2.3 2 0 0 2 2 2 2 Presenilin enhancer-2 subunit of gamma secretase RhoGEF PF00621.15 KPI44122.1 - 9.7e-27 93.9 0.0 1.5e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 KPI44122.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 PH domain BTB PF00651.26 KPI44123.1 - 1.1e-13 51.1 0.1 2.1e-13 50.2 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain Utp21 PF04192.7 KPI44124.1 - 8.3e-43 146.1 0.0 1.4e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KPI44124.1 - 1.7e-21 75.2 13.8 0.00013 21.6 0.2 9.1 10 0 0 10 10 10 5 WD domain, G-beta repeat PQQ PF01011.16 KPI44124.1 - 0.014 14.8 0.3 7.7 6.2 0.0 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat eIF2A PF08662.6 KPI44124.1 - 0.017 14.7 0.0 1.4 8.5 0.0 2.9 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KPI44124.1 - 0.11 10.8 0.0 0.26 9.5 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain Med16 PF11635.3 KPI44126.1 - 4.6e-07 28.2 0.0 5.4e-07 27.9 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 PWI PF01480.12 KPI44127.1 - 2.8e-09 36.9 0.3 7.9e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.17 KPI44127.1 - 0.0024 17.4 0.0 0.0063 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pribosyltran PF00156.22 KPI44128.1 - 8.7e-17 61.0 0.1 1.8e-16 60.0 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 KPI44128.1 - 0.029 13.6 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase NDUF_B8 PF05821.6 KPI44129.1 - 2.2e-09 37.2 0.1 2.7e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) AF1Q PF15017.1 KPI44129.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator PilJ PF13675.1 KPI44129.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Asp_Glu_race PF01177.17 KPI44130.1 - 5.3e-13 49.3 0.0 6.5e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Abhydrolase_6 PF12697.2 KPI44131.1 - 4.8e-17 62.6 0.1 5.7e-17 62.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI44131.1 - 8.5e-11 41.8 0.0 4.3e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI44131.1 - 6.3e-07 29.2 0.0 7.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KPI44131.1 - 0.0037 15.8 0.0 0.0052 15.3 0.0 1.1 1 0 0 1 1 1 1 Ndr family U-box PF04564.10 KPI44132.1 - 6.3e-23 80.5 0.0 3.9e-22 78.0 0.0 2.3 2 0 0 2 2 2 1 U-box domain TPR_11 PF13414.1 KPI44132.1 - 6.9e-14 51.2 5.9 3.5e-12 45.7 0.3 2.7 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KPI44132.1 - 7.6e-10 37.9 3.1 0.00086 18.8 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KPI44132.1 - 8e-10 37.8 6.3 0.0044 16.8 0.1 3.7 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KPI44132.1 - 3.9e-07 30.5 8.8 4.8e-05 23.9 1.7 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KPI44132.1 - 0.00062 19.6 7.2 0.0038 17.1 0.7 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KPI44132.1 - 0.002 18.2 2.5 0.39 10.8 0.2 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KPI44132.1 - 0.0065 16.1 1.7 0.27 11.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.4 KPI44132.1 - 0.035 13.4 0.1 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_19 PF14559.1 KPI44132.1 - 0.039 14.2 2.3 0.22 11.8 0.5 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 KPI44132.1 - 0.083 12.8 3.6 0.15 12.0 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KPI44132.1 - 0.58 10.9 0.2 0.58 10.9 0.1 4.3 3 2 1 4 4 4 0 Tetratricopeptide repeat Ndc1_Nup PF09531.5 KPI44133.1 - 3.1e-87 293.4 9.8 1.5e-86 291.1 6.8 1.8 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup RNR_inhib PF08591.5 KPI44134.1 - 7.3e-12 46.0 0.1 2e-11 44.6 0.1 1.8 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor Herpes_gE PF02480.11 KPI44135.1 - 0.012 13.9 0.0 0.019 13.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PIG-L PF02585.12 KPI44136.1 - 3e-10 40.6 0.0 5.5e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Cys_Met_Meta_PP PF01053.15 KPI44137.1 - 5.4e-137 456.1 0.0 6.5e-137 455.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KPI44137.1 - 2.9e-06 26.5 0.0 5.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KPI44137.1 - 7.6e-06 25.1 0.1 8.1e-05 21.8 0.1 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KPI44137.1 - 2.3e-05 23.3 0.1 3.9e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 KPI44137.1 - 0.0001 20.7 0.0 0.00073 17.9 0.0 1.9 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 KPI44137.1 - 0.00046 19.0 0.0 0.00065 18.4 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KPI44137.1 - 0.00083 18.5 0.3 0.0041 16.3 0.2 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.8 KPI44137.1 - 0.0034 16.1 0.1 0.0061 15.3 0.0 1.4 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Sec2p PF06428.6 KPI44138.1 - 8.6e-27 92.9 9.0 8.6e-27 92.9 6.3 2.7 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p DUF4250 PF14056.1 KPI44138.1 - 0.058 13.1 0.1 0.17 11.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) DUF3584 PF12128.3 KPI44138.1 - 0.17 9.2 19.5 0.26 8.5 13.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CASP_C PF08172.7 KPI44138.1 - 0.65 8.9 17.5 0.11 11.5 8.5 2.2 2 0 0 2 2 2 0 CASP C terminal Atg14 PF10186.4 KPI44138.1 - 0.83 8.5 19.0 1.9 7.3 5.5 2.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Tho2 PF11262.3 KPI44138.1 - 2.1 7.3 8.7 0.19 10.7 1.1 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 AAA_13 PF13166.1 KPI44138.1 - 4.5 5.5 12.5 7.8 4.8 8.7 1.3 1 0 0 1 1 1 0 AAA domain DUF2951 PF11166.3 KPI44138.1 - 8.5 6.3 8.6 2.7 7.8 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) Cauli_AT PF03233.8 KPI44138.1 - 8.9 5.9 7.0 0.69 9.6 0.5 2.2 2 0 0 2 2 2 0 Aphid transmission protein Oxysterol_BP PF01237.13 KPI44139.1 - 5.4e-66 222.4 0.0 1.5e-65 221.0 0.0 1.6 1 1 0 1 1 1 1 Oxysterol-binding protein adh_short PF00106.20 KPI44140.1 - 1.6e-29 102.9 0.1 2.4e-29 102.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI44140.1 - 6.1e-10 39.0 0.0 9e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI44140.1 - 6.9e-08 32.5 0.0 9.6e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KPI44140.1 - 1.6e-05 24.5 0.1 0.00054 19.6 0.0 2.5 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KPI44140.1 - 0.0072 15.4 0.0 0.0099 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KPI44140.1 - 0.024 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Pyr_redox_2 PF07992.9 KPI44141.1 - 2.9e-21 76.3 0.0 9.2e-20 71.3 0.0 3.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI44141.1 - 2e-10 40.8 0.0 1.5e-08 34.8 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI44141.1 - 0.018 15.0 0.0 7.9 6.5 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KPI44141.1 - 0.065 13.2 0.0 0.47 10.4 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FMN_dh PF01070.13 KPI44143.1 - 7.1e-119 396.8 0.0 8.8e-119 396.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KPI44143.1 - 0.0019 17.1 0.3 0.0035 16.2 0.2 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KPI44143.1 - 0.0071 15.4 0.8 1.9 7.5 0.0 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 KPI44143.1 - 0.0083 15.0 0.1 0.013 14.4 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 KPI44143.1 - 0.024 13.8 3.0 0.044 12.9 2.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.16 KPI44143.1 - 0.046 12.9 0.3 2.1 7.5 0.0 2.3 1 1 1 2 2 2 0 Histidine biosynthesis protein NAD_binding_2 PF03446.10 KPI44145.1 - 4.5e-33 114.3 0.1 8.3e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KPI44145.1 - 3.2e-12 46.7 0.1 3.5e-11 43.3 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 KPI44145.1 - 3.4e-11 43.2 0.4 5.6e-11 42.5 0.3 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 KPI44145.1 - 3e-08 33.8 0.2 8.4e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KPI44145.1 - 0.0042 17.0 0.1 0.0096 15.9 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain GFO_IDH_MocA PF01408.17 KPI44145.1 - 0.0078 16.7 0.0 0.025 15.1 0.0 1.9 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KPI44145.1 - 0.019 15.3 0.1 0.039 14.3 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KPI44145.1 - 0.14 11.5 0.4 0.83 9.0 0.1 2.4 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain EF-hand_7 PF13499.1 KPI44146.1 - 6.6e-14 51.8 0.8 2e-08 34.2 0.5 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KPI44146.1 - 3.6e-12 45.0 0.8 5.7e-05 22.6 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 KPI44146.1 - 1.4e-10 39.6 1.4 0.00034 19.7 0.0 3.7 4 1 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 KPI44146.1 - 1.5e-08 34.3 0.0 0.00083 19.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KPI44146.1 - 6.3e-08 32.1 2.5 0.00035 20.1 0.1 3.4 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KPI44146.1 - 0.011 15.0 2.5 2.2 7.7 0.7 2.9 2 0 0 2 2 2 0 EF hand UPF0154 PF03672.8 KPI44146.1 - 0.06 12.9 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Pkinase PF00069.20 KPI44147.1 - 4.2e-51 173.6 0.0 8.9e-51 172.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI44147.1 - 3.4e-25 88.5 0.0 3.1e-24 85.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KPI44147.1 - 0.019 13.7 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF2110 PF09883.4 KPI44147.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) IKI3 PF04762.7 KPI44149.1 - 2.9e-169 564.8 0.0 3.7e-169 564.5 0.0 1.1 1 0 0 1 1 1 1 IKI3 family Cyt-b5 PF00173.23 KPI44150.1 - 4.5e-14 51.9 0.0 7.5e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IL13 PF03487.8 KPI44151.1 - 2.6 7.8 4.8 3.4 7.4 0.1 3.1 3 0 0 3 3 3 0 Interleukin-13 Pyr_redox_3 PF13738.1 KPI44152.1 - 1.9e-25 90.1 0.0 1.4e-24 87.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI44152.1 - 5.1e-11 41.4 0.0 1.6e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KPI44152.1 - 1.8e-10 40.3 0.0 2e-08 33.5 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KPI44152.1 - 4e-10 39.1 0.1 3.7e-07 29.3 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI44152.1 - 5.9e-10 39.0 0.2 5.5e-08 32.7 0.0 3.2 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KPI44152.1 - 8.2e-06 25.0 0.1 0.00079 18.5 0.0 2.9 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.22 KPI44152.1 - 1.8e-05 25.0 0.0 0.089 13.2 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI44152.1 - 3.2e-05 23.8 0.3 0.49 10.2 0.0 3.3 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI44152.1 - 4.4e-05 22.5 0.1 0.0032 16.4 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KPI44152.1 - 0.0035 16.2 0.0 0.02 13.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 KPI44152.1 - 0.0059 15.5 0.4 2.3 6.9 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Shikimate_DH PF01488.15 KPI44152.1 - 0.025 14.6 0.0 0.54 10.3 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 KPI44152.1 - 0.035 13.8 1.9 1.8 8.3 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 KPI44152.1 - 0.077 13.2 0.0 0.4 10.9 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Mqo PF06039.10 KPI44152.1 - 0.11 10.6 0.0 3 5.9 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.9 KPI44152.1 - 0.14 10.5 0.6 1.7 6.9 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein RPE65 PF03055.10 KPI44153.1 - 1.4e-112 376.7 0.0 1.6e-112 376.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein His_Phos_2 PF00328.17 KPI44155.1 - 2.5e-96 323.0 0.0 2.1e-94 316.6 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KPI44155.1 - 1e-07 31.6 0.0 2.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Acetyltransf_1 PF00583.19 KPI44157.1 - 2.2e-09 37.1 0.1 4.6e-09 36.1 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KPI44157.1 - 1.4e-06 27.9 0.0 3.9e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KPI44157.1 - 3.9e-06 26.9 0.0 6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KPI44157.1 - 0.00073 19.7 0.1 0.0011 19.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KPI44157.1 - 0.025 14.4 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 KPI44157.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribonuc_L-PSP PF01042.16 KPI44158.1 - 2.1e-37 127.5 0.0 3.5e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP FAD_binding_3 PF01494.14 KPI44158.1 - 6.2e-11 41.9 1.7 6.3e-10 38.6 0.1 2.6 2 1 0 2 2 2 1 FAD binding domain SE PF08491.5 KPI44158.1 - 0.0011 17.8 0.0 0.0074 15.1 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.9 KPI44158.1 - 0.067 13.0 0.0 0.37 10.6 0.0 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4520 PF15016.1 KPI44158.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) DAO PF01266.19 KPI44158.1 - 0.13 11.1 1.7 3 6.6 0.2 3.0 3 1 0 3 3 3 0 FAD dependent oxidoreductase DUF202 PF02656.10 KPI44159.1 - 3.4e-16 59.1 4.1 1.7e-15 56.9 1.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) ADH_zinc_N PF00107.21 KPI44160.1 - 1.5e-32 111.8 0.0 2.4e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI44160.1 - 1.2e-08 35.9 0.0 2.2e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI44160.1 - 2.5e-07 30.4 0.0 9e-07 28.6 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KPI44160.1 - 0.034 13.7 2.0 0.044 13.3 1.0 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3827 PF12877.2 KPI44161.1 - 0.18 9.8 10.9 0.2 9.7 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Pol_alpha_B_N PF08418.5 KPI44161.1 - 8.6 5.8 11.7 10 5.5 8.1 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF3425 PF11905.3 KPI44162.1 - 3e-15 56.2 0.7 3e-15 56.2 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KPI44162.1 - 0.0014 18.5 17.5 0.0043 16.9 12.1 1.8 1 1 0 1 1 1 1 bZIP transcription factor BMFP PF04380.8 KPI44162.1 - 0.003 17.6 8.1 0.0053 16.8 5.6 1.4 1 0 0 1 1 1 1 Membrane fusogenic activity HALZ PF02183.13 KPI44162.1 - 0.0082 15.8 2.1 0.0093 15.6 0.4 1.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper NOC3p PF07540.6 KPI44162.1 - 0.057 13.6 1.3 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Nucleolar complex-associated protein bZIP_2 PF07716.10 KPI44162.1 - 0.07 12.9 21.6 0.083 12.7 5.0 2.3 1 1 1 2 2 2 0 Basic region leucine zipper LCD1 PF09798.4 KPI44162.1 - 0.13 10.2 0.6 0.41 8.5 0.9 1.4 2 0 0 2 2 2 0 DNA damage checkpoint protein DivIC PF04977.10 KPI44162.1 - 0.87 9.1 4.9 1.1 8.7 2.7 1.6 1 1 0 1 1 1 0 Septum formation initiator bZIP_Maf PF03131.12 KPI44162.1 - 2.5 8.4 13.8 4.2 7.7 9.6 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor IncA PF04156.9 KPI44162.1 - 8.9 5.8 7.1 14 5.1 4.9 1.2 1 0 0 1 1 1 0 IncA protein TauD PF02668.11 KPI44163.1 - 4.5e-36 124.8 0.0 6.3e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family VP7 PF00434.13 KPI44163.1 - 0.014 14.3 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein VP7 Anoctamin PF04547.7 KPI44164.1 - 5.4e-111 371.4 0.4 6.9e-111 371.0 0.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Aconitase PF00330.15 KPI44165.1 - 2.9e-155 517.2 0.0 9.2e-155 515.6 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KPI44165.1 - 3.5e-40 137.1 0.0 5.6e-40 136.4 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Abhydrolase_6 PF12697.2 KPI44166.1 - 7e-19 68.6 0.1 1.8e-17 63.9 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI44166.1 - 4.9e-10 39.3 0.0 6.9e-10 38.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI44166.1 - 0.00087 18.9 0.0 0.0024 17.4 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Relaxase PF03432.9 KPI44166.1 - 0.0023 17.3 1.2 0.0027 17.1 0.8 1.1 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain Ser_hydrolase PF06821.8 KPI44166.1 - 0.0071 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase PgaD PF13994.1 KPI44166.1 - 0.082 12.3 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 PgaD-like protein CoA_binding_2 PF13380.1 KPI44167.1 - 9.8e-09 35.4 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain DUF4430 PF14478.1 KPI44167.1 - 0.081 12.9 0.4 0.32 11.0 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4430) Complex1_LYR PF05347.10 KPI44168.1 - 8.7e-06 25.4 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KPI44168.1 - 0.003 17.7 0.0 0.0039 17.3 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Peptidase_M49 PF03571.10 KPI44169.1 - 6e-230 763.9 0.0 7.6e-230 763.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 DUF1311 PF07007.7 KPI44169.1 - 0.04 14.0 0.6 0.1 12.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1311) MFS_1 PF07690.11 KPI44170.1 - 1e-29 103.3 37.1 1.2e-22 80.1 11.7 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI44170.1 - 2.1e-10 39.7 13.3 2.1e-10 39.7 9.2 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KPI44170.1 - 0.0012 17.1 3.8 0.0012 17.1 2.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ESCRT-II PF05871.7 KPI44171.1 - 1.7e-48 164.0 0.4 3.8e-48 162.9 0.2 1.6 1 1 0 1 1 1 1 ESCRT-II complex subunit ADC PF06314.6 KPI44173.1 - 5.1e-14 52.1 0.0 6.5e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) ABC1 PF03109.11 KPI44174.1 - 3.9e-24 84.8 0.0 1.8e-14 53.7 0.0 2.8 3 0 0 3 3 3 2 ABC1 family APH PF01636.18 KPI44174.1 - 0.029 14.0 0.1 0.08 12.6 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Nexin_C PF08628.7 KPI44175.1 - 2.1e-25 89.0 0.6 7.6e-25 87.1 0.0 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 KPI44175.1 - 2e-21 75.8 0.6 2e-21 75.8 0.4 1.8 2 0 0 2 2 2 1 PX domain MFS_1 PF07690.11 KPI44177.1 - 1.2e-62 211.6 61.4 5e-40 137.3 3.6 3.7 2 1 1 4 4 4 4 Major Facilitator Superfamily OATP PF03137.15 KPI44177.1 - 9.6e-05 20.6 4.7 0.39 8.7 0.0 3.4 3 0 0 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family PHD PF00628.24 KPI44178.1 - 6.3e-07 28.9 6.8 1.2e-06 28.0 4.7 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 KPI44178.1 - 0.0018 18.5 0.0 0.0036 17.5 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding DUF1908 PF08926.6 KPI44179.1 - 0.44 9.2 2.6 0.57 8.8 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) BTB PF00651.26 KPI44180.1 - 3.7e-08 33.3 0.0 6.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Nop PF01798.13 KPI44181.1 - 2.8e-59 198.7 0.0 6.6e-59 197.5 0.0 1.6 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 KPI44181.1 - 1.1e-24 86.0 0.2 3.5e-24 84.3 0.1 2.0 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KPI44181.1 - 9.5e-22 76.9 0.0 9.5e-22 76.9 0.0 3.2 3 0 0 3 3 3 1 NOP5NT (NUC127) domain DUF606 PF04657.8 KPI44181.1 - 0.056 13.5 0.1 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF606 Chlorosome_CsmC PF11098.3 KPI44182.1 - 1.1 8.9 6.1 0.15 11.7 1.1 1.8 2 0 0 2 2 2 0 Chlorosome envelope protein C Fungal_trans_2 PF11951.3 KPI44183.1 - 3.7e-25 88.3 1.1 1.4e-20 73.2 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Bys1 PF04681.7 KPI44184.1 - 3.1e-06 26.9 2.8 6.4e-06 25.9 1.9 1.5 1 1 0 1 1 1 1 Blastomyces yeast-phase-specific protein Thaumatin PF00314.12 KPI44184.1 - 0.0027 17.2 1.7 0.77 9.1 0.0 2.7 1 1 2 3 3 3 2 Thaumatin family LRR_4 PF12799.2 KPI44186.1 - 1.5e-51 171.2 79.5 1.4e-09 37.3 0.5 6.3 1 1 9 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KPI44186.1 - 3.2e-35 119.6 84.5 4.8e-09 35.8 4.7 4.7 1 1 7 8 8 8 8 Leucine rich repeat LRR_1 PF00560.28 KPI44186.1 - 6.1e-15 52.9 33.9 0.079 13.0 0.1 10.2 11 0 0 11 11 11 6 Leucine Rich Repeat LRR_9 PF14580.1 KPI44186.1 - 1.4e-13 50.7 10.4 9e-07 28.6 0.8 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_7 PF13504.1 KPI44186.1 - 1.1e-12 45.8 23.7 0.24 11.7 0.1 9.1 9 1 1 10 10 10 5 Leucine rich repeat LRR_6 PF13516.1 KPI44186.1 - 9.1e-10 37.5 25.3 0.3 11.2 0.1 9.2 8 1 1 9 9 9 5 Leucine Rich repeat Phage_rep_org_N PF09681.5 KPI44186.1 - 0.034 13.7 1.2 5.1 6.6 0.1 3.0 1 1 2 3 3 3 0 N-terminal phage replisome organiser (Phage_rep_org_N) DUF3744 PF12558.3 KPI44186.1 - 1.7 9.1 10.6 8.2 6.9 0.4 4.5 1 1 3 4 4 4 0 ATP-binding cassette cobalt transporter PHD PF00628.24 KPI44187.1 - 7.9e-08 31.8 10.9 2.5e-07 30.2 7.5 1.9 1 1 1 2 2 2 1 PHD-finger PHD_2 PF13831.1 KPI44187.1 - 0.0083 15.4 5.7 0.0083 15.4 4.0 2.0 2 0 0 2 2 2 1 PHD-finger DDT PF02791.12 KPI44187.1 - 0.11 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 DDT domain N2227 PF07942.7 KPI44188.1 - 2.5e-23 82.3 0.0 3.6e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Aminotran_5 PF00266.14 KPI44189.1 - 8.1e-27 93.9 0.0 1.1e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KPI44189.1 - 0.063 12.4 0.0 0.097 11.7 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase Tim44 PF04280.10 KPI44190.1 - 1.1e-24 87.0 0.0 2.1e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Tim44-like domain MFS_1 PF07690.11 KPI44191.1 - 1.5e-39 135.6 33.0 2.3e-39 135.1 22.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TMEM237 PF15383.1 KPI44191.1 - 0.0018 17.4 1.0 0.0018 17.4 0.7 1.7 2 0 0 2 2 2 1 Transmembrane protein 237 DUF3040 PF11239.3 KPI44191.1 - 1.7 8.7 14.2 6.2 6.9 0.6 4.7 4 1 1 5 5 5 0 Protein of unknown function (DUF3040) Abhydrolase_6 PF12697.2 KPI44192.1 - 8.3e-17 61.8 6.6 1.9e-15 57.3 4.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI44192.1 - 2.1e-06 27.5 0.0 4.6e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI44192.1 - 0.0004 20.0 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ribonuc_L-PSP PF01042.16 KPI44193.1 - 2.5e-08 33.6 0.1 3.8e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP Ferric_reduct PF01794.14 KPI44194.1 - 6.6e-18 64.9 7.8 6.6e-18 64.9 5.4 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KPI44194.1 - 1.3e-12 47.9 0.0 6.4e-10 39.1 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KPI44194.1 - 8.2e-12 44.9 0.0 1.5e-06 28.0 0.1 2.3 2 0 0 2 2 2 2 FAD-binding domain HEAT PF02985.17 KPI44195.1 - 0.012 15.6 0.5 1.9 8.7 0.0 3.5 4 0 0 4 4 4 0 HEAT repeat DAO PF01266.19 KPI44196.1 - 8.2e-29 100.6 0.0 1.3e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI44196.1 - 0.00022 21.1 0.1 0.00078 19.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KPI44196.1 - 0.00086 19.6 0.0 0.21 12.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI44196.1 - 0.014 15.2 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KPI44196.1 - 0.017 15.0 0.0 2.6 7.8 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S10 PF00450.17 KPI44197.1 - 2e-88 297.3 0.9 2.5e-88 297.0 0.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase HMG_box PF00505.14 KPI44198.1 - 1.2e-14 54.2 0.5 2.1e-14 53.5 0.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box MFS_1 PF07690.11 KPI44200.1 - 2.5e-36 125.1 20.7 2.5e-36 125.1 14.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_28 PF03033.15 KPI44202.1 - 4.3e-15 55.7 0.1 6.7e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Ras PF00071.17 KPI44203.1 - 2.2e-57 192.9 0.0 2.8e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KPI44203.1 - 4.9e-20 72.2 0.0 8.9e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KPI44203.1 - 4.4e-14 52.1 0.0 1.7e-13 50.1 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KPI44203.1 - 8.4e-08 31.6 0.0 1.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KPI44203.1 - 6.8e-07 28.8 0.0 1.8e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KPI44203.1 - 7.3e-05 22.7 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KPI44203.1 - 0.031 14.4 0.0 0.29 11.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KPI44203.1 - 0.076 12.9 0.1 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain VWA_2 PF13519.1 KPI44203.1 - 0.094 12.8 2.3 1.3 9.0 1.6 2.1 1 1 0 1 1 1 0 von Willebrand factor type A domain UDPGT PF00201.13 KPI44204.1 - 0.0052 15.3 0.3 0.01 14.4 0.2 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KPI44204.1 - 0.074 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Mito_carr PF00153.22 KPI44205.1 - 3.2e-67 222.2 6.2 1.4e-24 85.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ArabFuran-catal PF09206.6 KPI44206.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B, catalytic MFS_1 PF07690.11 KPI44209.1 - 2.1e-14 53.0 44.2 2.5e-07 29.7 11.6 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily SprT-like PF10263.4 KPI44210.1 - 1.6e-36 125.3 0.0 2.4e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 SprT-like family SPT6_acidic PF14632.1 KPI44210.1 - 0.44 10.7 10.2 0.097 12.8 4.2 2.1 2 0 0 2 2 2 0 Acidic N-terminal SPT6 AA_permease PF00324.16 KPI44211.1 - 2.4e-105 352.6 40.9 3.2e-84 282.9 18.1 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KPI44211.1 - 1.7e-26 92.7 32.8 3.7e-22 78.4 17.2 2.0 1 1 1 2 2 2 2 Amino acid permease Colipase-like PF15083.1 KPI44213.1 - 0.21 11.5 3.3 0.31 11.0 2.3 1.2 1 0 0 1 1 1 0 Colipase-like DMPK_coil PF08826.5 KPI44215.1 - 0.062 13.2 0.5 0.19 11.6 0.3 1.8 1 0 0 1 1 1 0 DMPK coiled coil domain like DUF3713 PF12506.3 KPI44215.1 - 0.2 11.7 4.8 0.42 10.6 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) PDZ_assoc PF10600.4 KPI44216.1 - 0.03 14.6 0.0 0.045 14.0 0.0 1.2 1 0 0 1 1 1 0 PDZ-associated domain of NMDA receptors F-box PF00646.28 KPI44216.1 - 0.051 13.2 0.4 0.18 11.5 0.2 2.1 1 1 1 2 2 2 0 F-box domain TFIIE_alpha PF02002.12 KPI44216.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit Lactamase_B_2 PF12706.2 KPI44217.1 - 2.2e-13 50.2 0.0 4.3e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 KPI44217.1 - 0.00045 20.2 0.0 0.00091 19.2 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.22 KPI44217.1 - 0.0035 17.0 0.2 0.032 13.8 0.1 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily PAN_4 PF14295.1 KPI44218.1 - 1.9e-17 62.7 13.0 1.4e-05 24.6 0.4 4.1 3 0 0 3 3 3 3 PAN domain PAN_3 PF08277.7 KPI44218.1 - 0.0023 17.4 18.1 0.054 13.1 0.5 4.1 3 0 0 3 3 3 3 PAN-like domain zf-RING_2 PF13639.1 KPI44219.1 - 1.1e-13 50.7 5.1 2.1e-13 49.8 3.6 1.5 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KPI44219.1 - 1.8e-11 43.6 0.0 6.2e-11 41.8 0.0 1.9 2 0 0 2 2 2 1 PA domain zf-C3HC4_2 PF13923.1 KPI44219.1 - 1.1e-08 34.9 4.8 2.1e-08 34.0 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KPI44219.1 - 1.3e-08 34.7 1.6 2.9e-08 33.7 1.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KPI44219.1 - 4.1e-08 32.7 2.2 6.9e-08 32.0 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI44219.1 - 5.5e-08 32.4 1.9 9.2e-08 31.6 1.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KPI44219.1 - 6.9e-08 32.0 2.9 1.1e-07 31.3 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KPI44219.1 - 0.0043 16.8 0.6 0.0094 15.7 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KPI44219.1 - 0.058 13.1 2.3 0.14 11.9 1.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KPI44219.1 - 0.13 12.1 3.7 0.32 10.8 2.5 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KPI44219.1 - 0.14 11.7 2.8 0.25 10.9 1.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 KPI44219.1 - 0.19 11.8 2.9 0.37 10.8 2.0 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KPI44219.1 - 0.25 11.3 1.9 0.65 10.0 1.3 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 KPI44219.1 - 0.58 9.8 2.8 1.1 9.0 1.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 KPI44219.1 - 1.1 9.3 3.6 2.2 8.3 2.5 1.5 1 0 0 1 1 1 0 RING-like domain cNMP_binding PF00027.24 KPI44220.1 - 2.8e-41 139.2 0.1 5.6e-21 74.1 0.0 4.4 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 KPI44220.1 - 4.6e-17 62.6 5.4 4.6e-17 62.6 3.8 3.5 2 2 0 3 3 3 1 Patatin-like phospholipase Mitochondr_Som1 PF11093.3 KPI44221.1 - 2.6e-10 39.9 0.1 7.8e-10 38.4 0.2 1.8 2 1 0 2 2 2 1 Mitochondrial export protein Som1 Sporozoite_P67 PF05642.6 KPI44222.1 - 0.0011 17.0 3.2 0.0011 16.9 2.2 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen RAP1 PF07218.6 KPI44222.1 - 3.3 5.7 7.6 3.6 5.5 5.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cu_amine_oxid PF01179.15 KPI44223.1 - 3.9e-163 542.9 0.0 6.1e-163 542.3 0.0 1.3 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KPI44223.1 - 8.1e-09 35.4 0.0 3.3e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KPI44223.1 - 0.00022 21.2 0.4 0.00051 20.0 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Glyoxalase PF00903.20 KPI44224.1 - 1.1e-13 51.2 4.3 3.1e-11 43.3 1.2 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KPI44224.1 - 6e-09 36.4 1.1 4.5e-05 23.9 0.0 2.4 2 1 0 2 2 2 2 Glyoxalase-like domain RGS PF00615.14 KPI44225.1 - 8.9e-10 38.6 0.0 1.5e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Abhydrolase_3 PF07859.8 KPI44226.1 - 9.3e-18 64.5 0.0 1.4e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KPI44226.1 - 1.6e-14 53.3 0.0 4.1e-14 52.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KPI44226.1 - 1.2e-06 28.3 0.1 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family zf-MYND PF01753.13 KPI44227.1 - 1.1e-07 31.5 15.3 2e-07 30.7 10.6 1.5 1 0 0 1 1 1 1 MYND finger zf-FCS PF06467.9 KPI44227.1 - 8.9 6.0 11.2 53 3.5 6.6 2.9 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF2404 PF10296.4 KPI44228.1 - 0.00082 19.4 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) GST_N_3 PF13417.1 KPI44230.1 - 1.3e-17 63.7 0.0 2.4e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI44230.1 - 1.2e-13 50.8 0.1 4.1e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KPI44230.1 - 1.2e-13 50.6 0.0 2.6e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KPI44230.1 - 6.3e-12 45.3 0.0 9.8e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KPI44230.1 - 2.5e-07 31.0 0.0 4e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF223 PF02721.9 KPI44230.1 - 0.00086 19.3 0.0 0.0024 17.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF223 GST_N PF02798.15 KPI44230.1 - 0.0025 17.9 0.0 0.0051 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_L18e PF00828.14 KPI44232.1 - 8e-26 90.9 0.8 1.9e-25 89.6 0.6 1.6 1 1 0 1 1 1 1 Ribosomal protein L18e/L15 Gly-zipper_Omp PF13488.1 KPI44233.1 - 0.001 18.6 10.8 0.0042 16.6 6.4 2.3 2 0 0 2 2 2 1 Glycine zipper Rick_17kDa_Anti PF05433.10 KPI44233.1 - 0.0025 17.4 17.1 0.033 13.8 11.3 2.3 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 KPI44233.1 - 0.32 10.6 20.2 0.57 9.8 10.4 2.5 1 1 2 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain SecG PF03840.9 KPI44233.1 - 3.1 7.5 9.4 3.3 7.5 0.4 2.6 3 0 0 3 3 3 0 Preprotein translocase SecG subunit PCMT PF01135.14 KPI44234.1 - 1.2e-61 207.9 0.0 1.4e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KPI44234.1 - 2e-10 41.2 0.1 3.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI44234.1 - 5.1e-09 35.8 0.1 8.6e-09 35.1 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI44234.1 - 1.5e-06 28.2 0.0 2.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KPI44234.1 - 2.5e-06 27.2 0.0 3.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KPI44234.1 - 8.3e-06 25.2 0.0 1.5e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KPI44234.1 - 1.8e-05 24.5 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI44234.1 - 6.1e-05 23.3 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI44234.1 - 0.00013 21.2 0.0 0.00017 20.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KPI44234.1 - 0.00026 21.4 0.0 0.00053 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KPI44234.1 - 0.00027 19.7 0.0 0.00037 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 KPI44234.1 - 0.00087 19.7 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KPI44234.1 - 0.012 15.6 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_24 PF13578.1 KPI44234.1 - 0.02 15.7 0.0 0.041 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 KPI44234.1 - 0.028 13.7 0.1 0.043 13.1 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.8 KPI44234.1 - 0.045 12.8 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3328 PF11807.3 KPI44235.1 - 7.3e-22 78.1 4.0 1e-21 77.6 2.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) BSMAP PF12280.3 KPI44236.1 - 0.079 12.8 3.9 0.092 12.6 2.7 1.0 1 0 0 1 1 1 0 Brain specific membrane anchored protein DUF1510 PF07423.6 KPI44236.1 - 0.11 11.8 14.5 0.13 11.6 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 KPI44236.1 - 0.33 10.8 6.8 0.38 10.6 4.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Nop14 PF04147.7 KPI44236.1 - 0.65 7.8 18.2 0.75 7.6 12.6 1.0 1 0 0 1 1 1 0 Nop14-like family tRNA-synt_1 PF00133.17 KPI44236.1 - 0.76 7.6 7.7 1.1 7.1 5.4 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) Usp PF00582.21 KPI44236.1 - 0.84 9.8 8.1 1.1 9.4 5.6 1.2 1 0 0 1 1 1 0 Universal stress protein family Med19 PF10278.4 KPI44236.1 - 1 9.0 10.3 1.1 8.9 7.1 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DDHD PF02862.12 KPI44236.1 - 1.2 8.8 5.3 1.3 8.7 3.7 1.1 1 0 0 1 1 1 0 DDHD domain DHHW PF14286.1 KPI44236.1 - 2.1 7.5 6.7 2.3 7.4 4.7 1.0 1 0 0 1 1 1 0 DHHW protein RR_TM4-6 PF06459.7 KPI44236.1 - 2.6 7.8 17.3 3 7.6 12.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YqfQ PF14181.1 KPI44236.1 - 2.9 7.9 12.6 3.7 7.5 8.7 1.2 1 0 0 1 1 1 0 YqfQ-like protein CT47 PF15623.1 KPI44236.1 - 3.1 7.4 20.2 3.7 7.2 14.0 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Pilt PF15453.1 KPI44236.1 - 4 7.0 9.2 4.6 6.8 6.4 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions NARP1 PF12569.3 KPI44236.1 - 6.9 5.2 18.1 8.3 5.0 12.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Merozoite_SPAM PF07133.6 KPI44236.1 - 9.2 6.1 24.2 12 5.7 16.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Vfa1 PF08432.5 KPI44236.1 - 9.4 6.2 17.1 12 5.9 11.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GATase_5 PF13507.1 KPI44237.1 - 4.6e-71 238.7 0.0 9e-71 237.8 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 KPI44237.1 - 2.1e-44 151.2 0.1 1.1e-22 80.6 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KPI44237.1 - 6.7e-26 90.3 0.1 4.3e-25 87.7 0.0 2.5 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain MFS_1 PF07690.11 KPI44238.1 - 5.4e-34 117.4 35.1 5.4e-34 117.4 24.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Mmp37 PF09139.6 KPI44239.1 - 1.4e-135 451.5 0.0 1.8e-135 451.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Frag1 PF10277.4 KPI44240.1 - 3.5e-41 141.0 8.7 3.5e-41 141.0 6.0 2.5 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family Epimerase PF01370.16 KPI44241.1 - 3e-12 46.4 0.0 7.6e-12 45.1 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI44241.1 - 9.6e-09 34.3 0.0 2e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KPI44241.1 - 1.6e-06 28.2 0.0 6e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KPI44241.1 - 1.5e-05 24.4 0.0 2.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KPI44241.1 - 1.8e-05 23.7 0.0 0.00031 19.7 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KPI44241.1 - 0.0013 18.6 0.0 0.0048 16.8 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KPI44241.1 - 0.041 12.7 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_23 PF13489.1 KPI44242.1 - 4.2e-15 55.8 0.0 5.3e-15 55.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI44242.1 - 2.1e-05 25.0 0.2 0.18 12.3 0.1 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KPI44242.1 - 0.00094 19.6 0.0 0.23 11.9 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 KPI44242.1 - 0.001 18.6 0.0 0.25 10.9 0.1 2.1 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KPI44242.1 - 0.0011 19.4 0.0 0.06 13.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KPI44242.1 - 0.0093 15.1 0.0 0.12 11.4 0.0 2.0 1 1 1 2 2 2 1 Tellurite resistance protein TehB Methyltransf_25 PF13649.1 KPI44242.1 - 0.058 13.7 0.1 2.8 8.3 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain TP_methylase PF00590.15 KPI44243.1 - 3.3e-33 115.1 0.8 7.7e-33 113.9 0.5 1.6 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.1 KPI44243.1 - 7.3e-09 34.8 0.0 2.1e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.1 KPI44243.1 - 2.4e-06 27.7 0.0 5.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 KPI44243.1 - 0.00076 18.4 0.4 0.0015 17.4 0.3 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central SpoU_sub_bind PF08032.7 KPI44244.1 - 6.4e-09 35.8 0.0 2.4e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding SpoU_methylase PF00588.14 KPI44244.1 - 0.00037 20.3 0.0 0.00098 19.0 0.0 1.7 2 0 0 2 2 2 1 SpoU rRNA Methylase family DNA_repr_REX1B PF14966.1 KPI44245.1 - 0.11 12.8 0.1 2.3 8.6 0.0 2.3 2 0 0 2 2 2 0 DNA repair REX1-B FAA_hydrolase PF01557.13 KPI44246.1 - 2.6e-42 144.7 0.0 3.4e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KPI44246.1 - 2.8e-23 81.9 0.0 5.9e-23 80.9 0.0 1.5 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal DUF4134 PF13572.1 KPI44247.1 - 0.18 11.9 1.0 0.38 10.8 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) DASH_Dam1 PF08653.5 KPI44248.1 - 3.3e-26 90.8 0.5 4.4e-26 90.4 0.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 GIDA PF01134.17 KPI44249.1 - 3.1e-152 507.0 0.0 4e-152 506.6 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KPI44249.1 - 4.8e-15 55.3 0.0 2e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 KPI44249.1 - 5e-08 33.0 0.5 1.2e-07 31.8 0.4 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KPI44249.1 - 4.5e-07 29.3 0.6 7.6e-07 28.5 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KPI44249.1 - 8.8e-05 21.5 2.1 0.042 12.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI44249.1 - 0.00056 18.8 3.7 0.00072 18.5 1.5 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KPI44249.1 - 0.023 13.1 3.1 0.043 12.2 0.3 2.3 3 0 0 3 3 3 0 HI0933-like protein AlaDh_PNT_C PF01262.16 KPI44249.1 - 0.034 13.7 0.4 0.069 12.7 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 KPI44249.1 - 0.13 10.8 0.8 2.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.22 KPI44249.1 - 0.14 12.6 0.3 0.3 11.5 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Kelch_5 PF13854.1 KPI44249.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Kelch motif Thi4 PF01946.12 KPI44249.1 - 0.16 11.0 4.1 0.098 11.7 0.1 2.1 2 0 0 2 2 2 0 Thi4 family Med9 PF07544.8 KPI44250.1 - 1.7e-14 53.3 0.6 4.3e-13 48.8 0.2 2.3 2 1 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 EBP PF05241.7 KPI44251.1 - 3.1e-06 26.3 1.8 3.1e-06 26.3 1.3 1.6 2 0 0 2 2 2 1 Emopamil binding protein Acetyltransf_1 PF00583.19 KPI44253.1 - 6.3e-12 45.3 0.0 1.4e-11 44.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI44253.1 - 4.3e-09 36.4 0.0 1.1e-08 35.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KPI44253.1 - 3e-07 30.3 0.0 7.2e-05 22.6 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI44253.1 - 2e-05 24.6 0.0 3.9e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KPI44253.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GST_N_3 PF13417.1 KPI44254.1 - 3.2e-25 88.1 0.0 5.5e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI44254.1 - 1.4e-16 60.2 0.1 7.7e-16 57.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KPI44254.1 - 4.4e-08 33.1 0.0 9.3e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KPI44254.1 - 0.0097 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI44254.1 - 0.044 13.6 0.2 0.098 12.5 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Barwin PF00967.12 KPI44255.1 - 0.012 15.3 0.0 0.52 9.9 0.0 2.3 2 0 0 2 2 2 0 Barwin family HET PF06985.6 KPI44256.1 - 1.6e-06 28.3 0.0 0.0077 16.3 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RabGAP-TBC PF00566.13 KPI44257.1 - 9.5e-38 129.8 0.2 1.7e-37 129.0 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Zn_clus PF00172.13 KPI44258.1 - 1.3e-05 25.0 8.1 2.2e-05 24.2 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KPI44258.1 - 9.3e-05 21.1 0.0 0.00016 20.4 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 KPI44259.1 - 3.3e-33 115.0 6.4 3.3e-33 115.0 4.4 1.7 2 0 0 2 2 2 1 RTA1 like protein zf-DHHC PF01529.15 KPI44259.1 - 0.075 12.4 0.1 0.075 12.4 0.1 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF2976 PF11190.3 KPI44259.1 - 5.1 6.7 11.3 3.3 7.3 0.0 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF2976) Pex24p PF06398.6 KPI44259.1 - 9 4.9 6.2 20 3.8 4.0 1.7 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin WD40 PF00400.27 KPI44260.1 - 1.7e-22 78.4 18.0 3.7e-07 29.7 0.4 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_3 PF13570.1 KPI44260.1 - 0.00052 20.2 0.4 3.2 8.1 0.1 3.7 4 0 0 4 4 4 2 PQQ-like domain Cytochrom_D1 PF02239.11 KPI44260.1 - 0.0018 16.6 0.2 0.15 10.3 0.0 3.1 3 0 0 3 3 3 1 Cytochrome D1 heme domain PD40 PF07676.7 KPI44260.1 - 0.0058 16.2 0.9 0.016 14.8 0.0 2.3 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 KPI44260.1 - 0.021 13.6 0.1 3.4 6.2 0.1 3.0 2 1 0 2 2 2 0 Nup133 N terminal like Daxx PF03344.10 KPI44260.1 - 4.9 5.5 16.3 16 3.8 9.2 2.0 2 0 0 2 2 2 0 Daxx Family CENP-F_leu_zip PF10473.4 KPI44261.1 - 0.0037 17.1 16.2 0.32 10.8 6.7 2.7 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KPI44261.1 - 0.033 13.3 1.5 2.6 7.1 0.1 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein ATG16 PF08614.6 KPI44261.1 - 0.13 12.0 25.7 0.043 13.6 5.9 3.4 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Atg14 PF10186.4 KPI44261.1 - 0.31 9.9 14.5 0.055 12.4 4.7 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF641 PF04859.7 KPI44261.1 - 0.32 10.7 12.8 4.2 7.1 1.9 3.7 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF4201 PF13870.1 KPI44261.1 - 0.69 9.3 19.5 1.5 8.2 8.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) GAS PF13851.1 KPI44261.1 - 0.94 8.6 21.9 0.48 9.5 9.3 2.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 KPI44261.1 - 1.4 8.7 18.3 0.96 9.3 4.8 3.4 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Uds1 PF15456.1 KPI44261.1 - 2.6 8.0 16.1 0.68 9.9 6.2 3.0 2 1 0 2 2 2 0 Up-regulated During Septation PspA_IM30 PF04012.7 KPI44261.1 - 2.9 7.2 26.1 1.8 7.8 8.2 3.1 1 1 0 2 2 2 0 PspA/IM30 family TMF_DNA_bd PF12329.3 KPI44261.1 - 3.8 7.3 25.5 0.29 10.9 6.0 3.8 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 KPI44261.1 - 3.9 7.2 15.4 0.85 9.3 5.0 3.1 2 2 0 2 2 2 0 TATA element modulatory factor 1 TATA binding UPF0149 PF03695.8 KPI44262.1 - 0.02 14.8 0.9 0.02 14.8 0.6 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0149) His_Phos_2 PF00328.17 KPI44263.1 - 4e-24 85.6 0.0 4.9e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 KPI44263.1 - 0.0021 18.1 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1618 PF07762.9 KPI44263.1 - 0.1 12.8 0.0 7.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1618) PLA2_B PF01735.13 KPI44265.1 - 8.3e-17 60.5 0.0 2.1e-16 59.2 0.0 1.6 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Peptidase_S9 PF00326.16 KPI44265.1 - 0.00059 19.1 0.1 0.0015 17.7 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Arteri_GP4 PF02497.10 KPI44265.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Arterivirus glycoprotein RasGAP PF00616.14 KPI44266.1 - 4.1e-51 173.4 0.5 9.8e-51 172.2 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KPI44266.1 - 1.9e-32 111.9 1.5 1.9e-32 111.9 1.0 2.9 3 0 0 3 3 3 1 RasGAP C-terminus CD36 PF01130.16 KPI44266.1 - 0.014 13.7 0.1 0.03 12.6 0.1 1.5 1 0 0 1 1 1 0 CD36 family MitMem_reg PF13012.1 KPI44266.1 - 0.02 14.9 0.4 0.02 14.9 0.3 3.3 4 0 0 4 4 4 0 Maintenance of mitochondrial structure and function DUF972 PF06156.8 KPI44266.1 - 4 7.8 6.5 27 5.1 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) SAC3_GANP PF03399.11 KPI44267.1 - 1.1e-26 93.7 0.0 1.5e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KPI44267.1 - 7.4e-22 77.6 0.0 1.2e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Fungal_trans PF04082.13 KPI44268.1 - 2.5e-16 59.3 0.0 4.1e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI44268.1 - 3.7e-08 33.1 10.3 3.7e-08 33.1 7.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 KPI44269.1 - 8.4e-42 142.5 0.1 1.2e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI44269.1 - 8.2e-25 86.4 0.1 1.8e-24 85.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 KPI44269.1 - 0.012 14.7 0.1 0.025 13.6 0.1 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Granulin PF00396.13 KPI44270.1 - 2.7 8.1 17.8 2.1e+03 -1.2 12.3 2.6 1 1 0 1 1 1 0 Granulin Ribosomal_L30 PF00327.15 KPI44271.1 - 0.0096 15.4 0.1 0.03 13.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Beta-lactamase PF00144.19 KPI44272.1 - 3.1e-56 190.8 0.0 3.8e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase DUF1767 PF08585.7 KPI44273.1 - 1.3e-12 47.7 0.0 2.1e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Glyoxalase_2 PF12681.2 KPI44274.1 - 3e-05 24.5 0.0 3.3e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KPI44274.1 - 0.0043 17.0 0.0 0.0055 16.6 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily WD40 PF00400.27 KPI44275.1 - 1.7e-08 34.0 0.4 0.00038 20.2 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Fungal_trans PF04082.13 KPI44276.1 - 6e-24 84.3 0.0 1.2e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI44276.1 - 2.1e-11 43.5 12.6 3.8e-11 42.7 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3902 PF13042.1 KPI44276.1 - 0.026 13.8 0.1 0.047 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) NPR3 PF03666.8 KPI44278.1 - 4.7e-106 355.0 0.3 4.7e-106 355.0 0.2 3.1 2 1 1 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 Rep_4 PF05797.6 KPI44278.1 - 0.055 12.1 0.6 0.11 11.1 0.4 1.4 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) DUF3487 PF11990.3 KPI44278.1 - 0.15 11.4 0.8 0.32 10.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) Abhydrolase_4 PF08386.5 KPI44279.1 - 1.7e-18 66.3 0.0 4.3e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KPI44279.1 - 3.4e-09 36.6 0.6 1.1e-08 34.8 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI44279.1 - 3.5e-07 30.3 0.1 1.6e-06 28.1 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1295 PF06966.7 KPI44280.1 - 2.2e-09 36.9 0.0 2.9e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Put_Phosphatase PF06888.7 KPI44282.1 - 2.2e-37 128.4 0.2 1.4e-19 70.2 0.0 4.0 4 0 0 4 4 4 3 Putative Phosphatase HAD PF12710.2 KPI44282.1 - 7.2e-06 26.2 0.0 1.9e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase BCS1_N PF08740.6 KPI44284.1 - 1.1e-44 152.2 0.0 1.5e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KPI44284.1 - 4.4e-17 62.5 0.0 7.9e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KPI44284.1 - 6.5e-05 23.7 0.0 0.00015 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KPI44284.1 - 0.00017 21.0 0.0 0.00035 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KPI44284.1 - 0.00019 21.1 0.0 0.00052 19.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KPI44284.1 - 0.0016 18.4 0.1 0.018 15.0 0.0 2.6 1 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 KPI44284.1 - 0.0017 17.3 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 KPI44284.1 - 0.0034 17.5 0.0 0.011 15.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_21 PF13304.1 KPI44284.1 - 0.0043 17.0 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KPI44284.1 - 0.0096 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KPI44284.1 - 0.017 15.2 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KPI44284.1 - 0.026 14.8 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KPI44284.1 - 0.034 13.6 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 KPI44284.1 - 0.034 14.0 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KPI44284.1 - 0.042 13.6 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 1 0 Part of AAA domain AAA_28 PF13521.1 KPI44284.1 - 0.073 13.0 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KPI44284.1 - 0.09 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter PPV_E1_C PF00519.12 KPI44284.1 - 0.092 11.3 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_24 PF13479.1 KPI44284.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KPI44284.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 KPI44284.1 - 0.16 12.4 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 KPI44284.1 - 0.17 11.0 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KaiC PF06745.8 KPI44284.1 - 0.19 10.8 0.0 0.43 9.6 0.0 1.6 1 0 0 1 1 1 0 KaiC p450 PF00067.17 KPI44285.1 - 5.8e-52 176.7 0.0 7.3e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pex14_N PF04695.8 KPI44286.1 - 0.12 12.4 4.0 1.9 8.5 0.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-PARP PF00645.13 KPI44287.1 - 4e-21 75.0 0.7 4e-21 75.0 0.5 2.4 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region LytR_cpsA_psr PF03816.9 KPI44287.1 - 0.031 14.1 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 Cell envelope-related transcriptional attenuator domain GFO_IDH_MocA_C PF02894.12 KPI44288.1 - 3.3e-06 26.8 0.0 9.7e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Ribonuclease_T2 PF00445.13 KPI44290.1 - 2.3e-08 33.8 0.0 4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family Glyco_hydro_47 PF01532.15 KPI44291.1 - 5.6e-140 466.9 0.0 6.4e-140 466.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Rad51 PF08423.6 KPI44292.1 - 0.00012 21.1 0.1 0.00073 18.5 0.0 2.2 2 1 0 2 2 2 1 Rad51 Caleosin PF05042.8 KPI44292.1 - 0.082 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Caleosin related protein MFS_1 PF07690.11 KPI44293.1 - 7.9e-31 107.0 29.3 1.1e-30 106.5 20.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.20 KPI44294.1 - 1.3e-57 194.9 0.0 1.8e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI44294.1 - 6.9e-21 74.4 0.0 9.9e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KPI44294.1 - 2.5e-05 23.4 0.0 4.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KPI44294.1 - 3.6e-05 22.8 0.0 5.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KPI44294.1 - 0.00016 21.4 0.2 0.0086 15.8 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KPI44294.1 - 0.0074 15.6 0.2 0.023 14.0 0.1 1.7 1 1 0 1 1 1 1 RIO1 family PAS_9 PF13426.1 KPI44294.1 - 0.017 15.5 0.0 1.2 9.5 0.0 3.7 4 0 0 4 4 4 0 PAS domain AlaDh_PNT_N PF05222.10 KPI44295.1 - 1.6e-27 96.1 0.0 2.5e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KPI44295.1 - 6.5e-15 55.0 0.0 8.6e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ARD PF03079.9 KPI44297.1 - 3.7e-44 150.4 0.1 4.4e-44 150.1 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 KPI44297.1 - 3.9e-09 35.8 0.0 9.5e-09 34.6 0.0 1.6 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.14 KPI44297.1 - 1.2e-05 25.0 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KPI44297.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Cupin adh_short PF00106.20 KPI44298.1 - 7.3e-24 84.5 0.3 1.2e-23 83.8 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI44298.1 - 5.8e-19 68.8 0.1 6.9e-19 68.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI44298.1 - 9.2e-09 35.2 0.1 1.5e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Abhydrolase_6 PF12697.2 KPI44299.1 - 1.8e-22 80.3 0.0 2.1e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI44299.1 - 1e-12 48.0 0.0 1.2e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI44299.1 - 5.5e-11 42.4 0.0 6.3e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KPI44299.1 - 3.5e-06 26.7 0.1 7.9e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 KPI44299.1 - 5.8e-05 23.4 0.0 6.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF2305 PF10230.4 KPI44299.1 - 0.0017 17.8 0.2 0.0029 17.0 0.1 1.5 1 1 1 2 2 2 1 Uncharacterised conserved protein (DUF2305) Chlorophyllase2 PF12740.2 KPI44299.1 - 0.0023 16.8 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 KPI44299.1 - 0.0023 17.5 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1057 PF06342.7 KPI44299.1 - 0.0033 16.2 0.0 0.0044 15.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Lipase_3 PF01764.20 KPI44299.1 - 0.0065 16.0 0.0 0.014 15.0 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) Esterase PF00756.15 KPI44299.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF900 PF05990.7 KPI44299.1 - 0.026 13.8 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Chlorophyllase PF07224.6 KPI44299.1 - 0.032 13.0 0.1 0.099 11.4 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase Hydrolase_4 PF12146.3 KPI44299.1 - 0.073 12.9 0.0 0.26 11.1 0.0 1.9 1 1 1 2 2 2 0 Putative lysophospholipase DUF915 PF06028.6 KPI44299.1 - 0.087 11.8 0.0 0.89 8.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Yae1_N PF09811.4 KPI44301.1 - 3.8e-09 35.9 0.0 6.4e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Lactamase_B PF00753.22 KPI44301.1 - 5.1e-08 32.8 0.1 9.5e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KPI44301.1 - 1.5e-06 27.8 0.2 2.7e-06 27.0 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KPI44301.1 - 0.00053 19.7 0.0 0.00089 19.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Dor1 PF04124.7 KPI44302.1 - 3.3e-45 154.0 6.6 2.1e-32 111.9 4.4 2.1 2 0 0 2 2 2 2 Dor1-like family DUF4413 PF14372.1 KPI44302.1 - 0.0057 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Methyltransf_2 PF00891.13 KPI44303.1 - 1.1e-21 77.1 0.2 2.5e-17 62.9 0.0 2.2 1 1 1 2 2 2 2 O-methyltransferase Dimerisation PF08100.6 KPI44303.1 - 0.02 14.6 0.3 0.11 12.3 0.0 2.4 3 0 0 3 3 3 0 Dimerisation domain MFS_1 PF07690.11 KPI44304.1 - 2.8e-36 124.9 35.0 2.8e-36 124.9 24.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI44304.1 - 0.00021 20.0 3.3 0.00021 20.0 2.3 2.9 2 1 0 3 3 3 1 Sugar (and other) transporter Nuc_deoxyrib_tr PF05014.10 KPI44305.1 - 4.3e-14 52.3 0.0 7.2e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase CDP-OH_P_transf PF01066.16 KPI44306.1 - 1.8e-12 47.3 3.1 1.8e-12 47.3 2.2 1.5 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pep_deformylase PF01327.16 KPI44307.1 - 3.3e-27 94.8 0.0 4.2e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Transthyretin PF00576.16 KPI44308.1 - 3.5e-22 78.4 0.1 1.3e-20 73.3 0.1 2.1 1 1 0 1 1 1 1 HIUase/Transthyretin family DUF3355 PF11835.3 KPI44308.1 - 0.24 11.2 14.0 0.12 12.1 8.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3355) Acyl-CoA_dh_N PF02771.11 KPI44309.1 - 1.1e-19 71.0 0.0 4.4e-19 69.1 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KPI44309.1 - 3.8e-12 45.5 0.3 1.2e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain UCH PF00443.24 KPI44310.1 - 3.6e-52 177.1 0.2 4.6e-52 176.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KPI44310.1 - 1.6e-26 93.4 0.3 3.2e-26 92.4 0.2 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KPI44310.1 - 0.0021 18.1 0.5 0.0021 18.1 0.3 3.1 4 1 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein DUF2082 PF09855.4 KPI44310.1 - 0.052 13.4 6.6 0.35 10.7 0.1 3.6 4 0 0 4 4 4 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) ZZ PF00569.12 KPI44310.1 - 0.22 11.1 5.0 1.6 8.2 0.1 3.7 3 0 0 3 3 3 0 Zinc finger, ZZ type BTB PF00651.26 KPI44312.1 - 2.3e-14 53.3 0.0 3.5e-13 49.5 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain FAD_binding_7 PF03441.9 KPI44313.1 - 1.7e-74 250.5 0.6 3.4e-73 246.2 0.4 2.0 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KPI44313.1 - 3.7e-31 108.1 0.0 6.3e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Sel1 PF08238.7 KPI44313.1 - 0.33 11.6 2.6 5.5 7.7 1.8 2.6 1 1 0 1 1 1 0 Sel1 repeat Sugar_tr PF00083.19 KPI44314.1 - 2.8e-100 336.0 16.0 3.3e-100 335.7 11.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI44314.1 - 7.3e-31 107.1 49.9 6.8e-27 94.1 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tmemb_18A PF09771.4 KPI44314.1 - 0.1 12.5 0.6 3.5 7.6 0.1 2.9 3 0 0 3 3 3 0 Transmembrane protein 188 Asp PF00026.18 KPI44315.1 - 2.1e-65 221.0 1.9 3.3e-65 220.4 1.3 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KPI44315.1 - 5.7e-08 32.8 4.0 9.4e-08 32.1 0.1 3.0 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KPI44315.1 - 0.00034 20.1 0.0 0.0007 19.1 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KPI44315.1 - 0.0006 20.2 7.6 0.32 11.5 0.5 4.2 3 1 0 3 3 3 2 Aspartyl protease MFS_1 PF07690.11 KPI44317.1 - 5.2e-40 137.2 30.3 5.2e-40 137.2 21.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Adaptin_N PF01602.15 KPI44318.1 - 6.2e-142 473.5 4.1 7.5e-142 473.3 2.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KPI44318.1 - 6.9e-18 65.0 0.0 1.8e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KPI44318.1 - 9.8e-06 25.7 1.9 0.49 10.7 0.0 4.6 5 1 0 5 5 5 2 HEAT repeats Cnd1 PF12717.2 KPI44318.1 - 0.00077 19.3 1.8 0.021 14.6 0.3 3.3 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KPI44318.1 - 0.0053 16.7 1.7 13 6.1 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat TIP120 PF08623.5 KPI44318.1 - 0.017 14.7 0.5 0.082 12.4 0.0 2.3 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Arm PF00514.18 KPI44318.1 - 0.13 12.1 1.4 52 3.8 0.0 5.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat CWC25 PF12542.3 KPI44319.1 - 6.6e-27 93.7 3.5 6.6e-27 93.7 2.4 3.4 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 KPI44319.1 - 3.7e-14 52.4 12.8 3.7e-14 52.4 8.9 2.7 2 1 1 3 3 3 2 N-terminal domain of CBF1 interacting co-repressor CIR HrpA_pilin PF09589.5 KPI44319.1 - 9 6.7 13.6 0.21 12.0 1.6 3.0 3 1 0 3 3 3 0 HrpA pilus formation protein 2OG-FeII_Oxy_3 PF13640.1 KPI44320.1 - 1e-10 41.9 0.0 2.9e-10 40.5 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KPI44320.1 - 4.5e-05 22.9 0.2 0.00011 21.7 0.1 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Marek_A PF02124.10 KPI44320.1 - 0.1 12.0 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 Marek's disease glycoprotein A U3_assoc_6 PF08640.6 KPI44321.1 - 5.2e-27 93.4 2.2 5.2e-27 93.4 1.5 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 KPI44321.1 - 5.1e-08 32.1 2.1 2.5e-06 26.6 1.4 2.8 2 1 1 3 3 3 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KPI44321.1 - 9.3e-05 22.7 5.2 0.15 12.8 0.1 5.5 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KPI44321.1 - 0.0073 16.6 3.0 0.033 14.5 0.0 3.4 3 2 0 3 3 3 1 Tetratricopeptide repeat SAM_1 PF00536.25 KPI44321.1 - 0.098 12.8 0.0 13 6.0 0.0 3.4 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) PCI PF01399.22 KPI44322.1 - 1.9e-10 41.0 0.0 6.4e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.12 KPI44322.1 - 0.00061 19.5 0.9 0.0022 17.7 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KPI44322.1 - 0.011 15.4 0.1 0.028 14.0 0.1 1.7 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.23 KPI44322.1 - 0.028 14.0 1.0 0.085 12.4 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Xpo1 PF08389.7 KPI44323.1 - 0.00019 21.3 7.7 0.00088 19.2 0.1 4.1 4 0 0 4 4 4 1 Exportin 1-like protein DUF3384 PF11864.3 KPI44323.1 - 0.015 13.7 0.7 0.17 10.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3384) IBN_N PF03810.14 KPI44323.1 - 0.039 13.8 0.0 0.16 11.9 0.0 2.2 1 0 0 1 1 1 0 Importin-beta N-terminal domain Erf4 PF10256.4 KPI44323.1 - 0.1 12.4 0.0 1.3 8.8 0.0 2.8 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family SpoU_methylase PF00588.14 KPI44324.1 - 3.2e-10 40.0 0.0 3.5e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family PhyH PF05721.8 KPI44325.1 - 1.6e-36 126.3 0.0 2e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 KPI44325.1 - 0.016 15.4 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.1 KPI44325.1 - 0.024 15.1 0.5 0.14 12.6 0.0 2.4 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Cupin_2 PF07883.6 KPI44326.1 - 7.8e-06 25.2 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Form_Nir_trans PF01226.12 KPI44328.1 - 3.3e-50 170.3 11.4 3.8e-50 170.1 7.9 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Glyco_hydro_3 PF00933.16 KPI44329.1 - 3.3e-94 315.2 0.0 4.8e-94 314.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KPI44329.1 - 1.3e-49 168.8 0.0 2.5e-49 167.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KPI44329.1 - 5.5e-14 51.8 0.2 1.1e-13 50.8 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PIR PF00399.14 KPI44329.1 - 0.00062 19.0 2.1 0.0016 17.7 1.5 1.7 1 0 0 1 1 1 1 Yeast PIR protein repeat NAD_binding_10 PF13460.1 KPI44331.1 - 3.6e-16 59.6 0.4 5.6e-16 59.0 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI44331.1 - 3.4e-06 26.6 0.0 6e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 KPI44332.1 - 4.2e-13 48.9 0.0 9.2e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI44332.1 - 2.2e-12 46.7 0.1 6e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KPI44332.1 - 0.013 16.3 0.0 0.026 15.4 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase FliE PF02049.13 KPI44332.1 - 0.087 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE PGM_PMM_I PF02878.11 KPI44333.1 - 1.1e-18 67.0 0.2 2.2e-09 36.9 0.0 2.9 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KPI44333.1 - 6.1e-15 55.4 0.3 1.2e-13 51.3 0.0 3.0 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KPI44333.1 - 1.2e-10 41.2 0.7 4.3e-10 39.4 0.4 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 KPI44333.1 - 0.061 13.3 0.1 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF1279 PF06916.8 KPI44334.1 - 2.6e-30 104.5 0.0 4.7e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Spectrin PF00435.16 KPI44335.1 - 0.23 11.7 11.9 0.73 10.1 0.8 4.1 3 1 1 4 4 4 0 Spectrin repeat DUF4407 PF14362.1 KPI44335.1 - 1.6 7.6 7.7 3.7 6.4 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Gp-FAR-1 PF05823.7 KPI44335.1 - 3.9 7.4 8.4 2 8.3 2.0 2.4 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) tRNA-synt_2 PF00152.15 KPI44336.1 - 5.9e-66 222.5 0.0 5.3e-65 219.4 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 KPI44336.1 - 1.7e-06 27.4 0.1 0.0029 16.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 KPI44336.1 - 0.00097 18.9 0.1 0.0021 17.8 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 KPI44336.1 - 0.009 15.6 0.1 1.5 8.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) WD40 PF00400.27 KPI44337.1 - 1.8e-21 75.1 18.8 2.6e-08 33.4 0.2 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KPI44337.1 - 0.00035 18.9 0.0 0.00069 18.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.6 KPI44337.1 - 0.00044 20.0 0.0 0.0055 16.4 0.0 2.5 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 KPI44337.1 - 0.95 9.1 7.1 2.9 7.5 0.8 2.7 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term CUE PF02845.11 KPI44338.1 - 4.1e-05 22.9 0.2 0.00011 21.6 0.1 1.8 1 0 0 1 1 1 1 CUE domain DUF4146 PF13652.1 KPI44338.1 - 0.0088 15.8 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4146) Cellulase PF00150.13 KPI44339.1 - 2.5e-13 49.8 3.4 1.2e-08 34.5 0.8 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 KPI44339.1 - 0.00059 19.0 4.5 0.036 13.1 0.1 2.4 3 0 0 3 3 3 2 Beta-galactosidase Glyco_hydro_35 PF01301.14 KPI44339.1 - 0.0096 15.3 0.2 0.024 14.0 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 Chalcone PF02431.10 KPI44340.1 - 1.5e-61 207.2 0.0 2.9e-61 206.3 0.0 1.4 1 0 0 1 1 1 1 Chalcone-flavanone isomerase FXR1P_C PF12235.3 KPI44340.1 - 0.017 15.2 4.8 0.034 14.2 3.3 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal DUF3433 PF11915.3 KPI44341.1 - 1.4e-09 37.9 0.9 3.8e-09 36.5 0.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) DUF4605 PF15378.1 KPI44341.1 - 0.04 13.6 1.8 0.064 12.9 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) Abhydrolase_6 PF12697.2 KPI44343.1 - 8.6e-14 51.9 0.0 1.5e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI44343.1 - 6e-13 48.8 0.2 9.3e-11 41.7 0.0 2.4 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI44343.1 - 0.00034 20.4 0.1 0.0049 16.6 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 KPI44343.1 - 0.0043 16.5 0.1 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase HCBP_related PF06594.6 KPI44343.1 - 0.097 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain TIMELESS PF04821.9 KPI44345.1 - 2.2e-85 286.1 0.0 2.2e-85 286.1 0.0 1.9 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.8 KPI44345.1 - 1.2e-30 106.9 30.7 1.2e-30 106.9 21.3 3.8 3 1 0 3 3 3 2 Timeless protein C terminal region Fungal_trans_2 PF11951.3 KPI44346.1 - 6.5e-09 34.8 0.1 1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.2 KPI44347.1 - 3.3e-14 52.9 0.1 5.8e-07 29.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KPI44347.1 - 2.6e-09 37.0 0.1 0.0026 17.9 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KPI44347.1 - 1.1e-08 34.4 0.1 0.0012 18.5 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KPI44347.1 - 1.6e-08 33.9 0.0 0.004 17.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KPI44347.1 - 7.2e-05 23.1 0.1 0.0047 17.3 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Clathrin PF00637.15 KPI44347.1 - 0.031 13.8 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Region in Clathrin and VPS GTP_EFTU PF00009.22 KPI44348.1 - 3.8e-57 192.7 0.0 5.6e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KPI44348.1 - 1.6e-36 124.4 0.1 4e-36 123.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KPI44348.1 - 7.1e-16 58.0 2.2 7.1e-16 58.0 1.5 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 TFIIS_C PF01096.13 KPI44348.1 - 9.1e-12 44.4 0.2 1.8e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) GTP_EFTU_D4 PF14578.1 KPI44348.1 - 0.0002 20.9 0.6 0.00053 19.5 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KPI44348.1 - 0.00074 19.4 0.2 0.0022 17.9 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase PDZ PF00595.19 KPI44348.1 - 0.047 13.8 0.6 0.21 11.7 0.0 2.4 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) G-alpha PF00503.15 KPI44348.1 - 0.12 11.0 0.0 0.21 10.2 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit WD40 PF00400.27 KPI44349.1 - 4.6e-28 96.0 1.5 4.7e-13 48.4 0.1 5.4 5 1 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KPI44349.1 - 4.1e-05 23.1 0.1 0.0013 18.2 0.0 2.4 1 1 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 KPI44349.1 - 0.00036 18.9 0.1 0.0013 17.1 0.1 1.7 1 1 1 2 2 2 1 Cytochrome D1 heme domain eIF2A PF08662.6 KPI44349.1 - 0.001 18.8 0.3 2.2 7.9 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KPI44349.1 - 0.0056 14.8 0.0 0.014 13.5 0.0 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KPI44349.1 - 0.0097 14.6 0.0 0.94 8.1 0.0 2.6 1 1 2 3 3 3 2 Nup133 N terminal like Gmad1 PF10647.4 KPI44349.1 - 0.015 14.7 0.0 0.029 13.7 0.0 1.5 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain WSC PF01822.14 KPI44350.1 - 1.3e-06 28.2 4.0 1.3e-06 28.2 2.8 4.1 4 1 1 5 5 5 1 WSC domain PAN_4 PF14295.1 KPI44350.1 - 0.0015 18.2 5.6 0.23 11.1 0.0 4.1 3 0 0 3 3 3 2 PAN domain SWIB PF02201.13 KPI44351.1 - 3.7e-14 52.1 0.0 8.2e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain SPX PF03105.14 KPI44352.1 - 3.1e-43 148.5 6.4 4.1e-43 148.1 4.4 1.2 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 KPI44352.1 - 4.9e-08 32.7 12.9 2.1e-07 30.7 8.0 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KPI44352.1 - 1.7e-06 27.6 9.6 3.5e-06 26.6 6.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KPI44352.1 - 3.3e-06 26.6 8.6 6.2e-06 25.7 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI44352.1 - 5.4e-06 26.3 12.7 1.1e-05 25.3 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KPI44352.1 - 6.2e-06 25.9 11.6 1.2e-05 25.0 8.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KPI44352.1 - 2.2e-05 24.0 11.9 2.2e-05 24.0 8.3 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KPI44352.1 - 0.0068 16.4 3.1 0.016 15.3 2.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KPI44352.1 - 0.0081 15.9 2.6 0.016 15.0 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KPI44352.1 - 0.011 15.2 3.7 0.011 15.2 2.6 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TerY-C PF15616.1 KPI44352.1 - 0.018 14.9 2.6 0.047 13.6 1.8 1.7 1 0 0 1 1 1 0 TerY-C metal binding domain zf-MIZ PF02891.15 KPI44352.1 - 0.019 14.5 8.8 0.038 13.4 6.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 KPI44352.1 - 0.038 13.7 9.3 0.16 11.7 6.4 2.2 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 KPI44352.1 - 0.13 12.0 4.2 0.32 10.7 2.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 KPI44352.1 - 0.51 9.9 5.0 1.3 8.5 3.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-P11 PF03854.9 KPI44352.1 - 0.84 9.1 8.7 10 5.6 6.0 2.2 1 1 1 2 2 2 0 P-11 zinc finger MbeD_MobD PF04899.7 KPI44352.1 - 1.6 8.6 6.6 3.8 7.4 0.4 3.0 2 1 1 3 3 3 0 MbeD/MobD like FMN_dh PF01070.13 KPI44353.1 - 1e-107 360.1 0.0 1.3e-107 359.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KPI44353.1 - 1.2e-17 63.4 0.1 3.1e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KPI44353.1 - 2.4e-05 23.4 0.1 3.6e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KPI44353.1 - 5.9e-05 22.1 0.1 0.00035 19.5 0.0 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KPI44353.1 - 0.0054 15.8 0.1 1.5 7.8 0.0 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 KPI44353.1 - 0.0072 15.5 0.4 0.076 12.1 0.0 2.5 2 1 0 3 3 3 1 Nitronate monooxygenase DHO_dh PF01180.16 KPI44353.1 - 0.072 12.0 0.0 0.18 10.7 0.0 1.7 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 KPI44353.1 - 0.098 11.9 0.0 0.44 9.7 0.0 2.0 1 1 1 2 2 2 0 Histidine biosynthesis protein Lactamase_B_2 PF12706.2 KPI44355.1 - 2.4e-30 105.5 0.1 3.2e-30 105.1 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KPI44355.1 - 2.2e-11 43.7 0.1 3.7e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KPI44355.1 - 4.5e-06 26.4 0.1 0.0002 21.0 0.0 2.4 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily zf-C2H2 PF00096.21 KPI44356.1 - 3.8e-07 30.0 16.5 1.6e-05 24.9 1.9 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KPI44356.1 - 4.7e-05 23.4 3.8 4.7e-05 23.4 2.6 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KPI44356.1 - 0.00099 19.1 0.7 0.0033 17.5 0.5 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KPI44356.1 - 0.0011 19.1 0.9 0.0011 19.1 0.6 3.7 4 0 0 4 4 4 1 C2H2-type zinc finger zf-TRAF PF02176.13 KPI44356.1 - 0.86 10.0 7.6 0.33 11.3 1.7 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger p450 PF00067.17 KPI44357.1 - 6.3e-61 206.3 0.0 5.5e-60 203.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.7 KPI44358.1 - 6.9e-30 103.0 0.6 1.1e-29 102.4 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI44358.1 - 2e-16 59.7 0.0 2.9e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_16 PF00722.16 KPI44359.1 - 2.1e-10 40.2 0.2 3.6e-10 39.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Nitroreductase PF00881.19 KPI44360.1 - 2.3e-10 40.5 0.2 3.3e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 Nitroreductase family DUF2574 PF10836.3 KPI44360.1 - 0.07 12.8 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) FAA_hydrolase PF01557.13 KPI44361.1 - 1.5e-65 220.7 0.0 2e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family La PF05383.12 KPI44362.1 - 2.4e-17 62.4 0.0 4.8e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 La domain adh_short PF00106.20 KPI44364.1 - 7.9e-24 84.4 0.0 1.1e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI44364.1 - 1.9e-10 40.6 0.0 2.9e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KPI44364.1 - 0.00067 18.6 0.0 0.0011 17.8 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein EMP24_GP25L PF01105.19 KPI44365.1 - 8.3e-43 146.2 0.0 1e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Microtub_assoc PF07989.6 KPI44367.1 - 5.2e-20 71.0 9.4 5.2e-20 71.0 6.5 8.1 7 2 2 9 9 9 1 Microtubule associated Mto2_bdg PF12808.2 KPI44367.1 - 1.1e-19 70.2 28.7 4e-17 62.0 12.5 11.1 12 1 0 12 12 12 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 KPI44367.1 - 0.0001 21.6 3.8 0.0001 21.6 2.6 5.5 2 1 4 6 6 6 2 Reovirus sigma C capsid protein LPP PF04728.8 KPI44367.1 - 3.8 7.3 14.3 1.4 8.8 2.8 3.9 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Fungal_trans_2 PF11951.3 KPI44368.1 - 9.1e-09 34.3 4.3 2.4e-08 33.0 3.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KPI44369.1 - 1.3e-21 76.6 37.5 1.3e-21 76.6 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 KPI44370.1 - 1.9e-19 70.2 0.0 2.7e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI44370.1 - 5.4e-09 35.9 0.0 9.3e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI44370.1 - 1.9e-05 24.5 0.0 2.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KPI44370.1 - 0.00067 18.6 0.0 0.00084 18.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KPI44370.1 - 0.0018 17.7 0.0 0.0041 16.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KPI44370.1 - 0.0064 15.7 0.0 0.013 14.7 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 KPI44370.1 - 0.0084 16.1 0.0 0.027 14.4 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Methyltrn_RNA_3 PF02598.12 KPI44371.1 - 1e-82 277.7 0.0 1.2e-82 277.5 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase XPG_N PF00752.12 KPI44371.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 XPG N-terminal domain zf-C2H2 PF00096.21 KPI44373.1 - 0.024 14.9 3.7 0.024 14.9 2.6 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI44373.1 - 2.9 8.4 13.0 0.19 12.1 2.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Ras PF00071.17 KPI44375.1 - 2.6e-54 182.9 0.0 3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KPI44375.1 - 3.3e-16 59.8 0.0 4.6e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KPI44375.1 - 4.3e-08 32.5 0.0 5.1e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FAD_binding_3 PF01494.14 KPI44376.1 - 1.2e-06 27.8 0.4 2.4e-05 23.5 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain MutS_V PF00488.16 KPI44377.1 - 7.5e-67 225.1 0.0 1.9e-56 191.0 0.0 2.5 1 1 1 2 2 2 2 MutS domain V MutS_III PF05192.13 KPI44377.1 - 1.9e-40 138.8 1.6 4.7e-40 137.5 1.1 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 KPI44377.1 - 2.6e-21 76.1 1.8 5.4e-21 75.0 0.1 2.5 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 KPI44377.1 - 1.5e-16 60.3 1.3 1.5e-16 60.3 0.9 2.5 2 1 1 3 3 3 1 MutS family domain IV MutS_I PF01624.15 KPI44377.1 - 6.1e-13 48.7 0.0 5.7e-12 45.6 0.0 2.4 2 0 0 2 2 2 1 MutS domain I Sec1 PF00995.18 KPI44378.1 - 2.8e-148 495.0 0.0 3.2e-148 494.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_tran_WecB PF03808.8 KPI44378.1 - 0.072 12.4 0.0 15 4.9 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family HAD_2 PF13419.1 KPI44379.1 - 3.6e-11 43.6 0.0 2.6e-09 37.5 0.0 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KPI44379.1 - 2.5e-05 23.8 0.1 5.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KPI44379.1 - 5.5e-05 23.6 0.0 0.02 15.2 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KPI44379.1 - 0.00014 22.1 0.0 0.00018 21.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 KPI44379.1 - 0.051 12.9 0.1 0.19 11.0 0.0 1.9 3 0 0 3 3 3 0 Mitochondrial PGP phosphatase Pkinase PF00069.20 KPI44380.1 - 2.3e-78 262.9 0.0 8.4e-64 215.2 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KPI44380.1 - 1e-44 152.5 0.0 5.4e-43 146.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI44380.1 - 3.3e-11 42.6 0.0 1.8e-08 33.6 0.0 3.1 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 KPI44380.1 - 1e-05 24.7 0.0 0.0041 16.2 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KPI44380.1 - 3.2e-05 23.8 0.1 0.041 13.6 0.0 2.8 3 0 0 3 3 3 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KPI44380.1 - 0.21 10.3 0.1 3.9 6.2 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 DEAD PF00270.24 KPI44381.1 - 4e-20 71.9 0.0 8.4e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KPI44381.1 - 3.4e-11 43.3 1.2 2.4e-10 40.5 0.0 2.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KPI44381.1 - 3.3e-07 30.0 0.1 7.6e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 KPI44381.1 - 0.16 11.1 0.0 0.38 9.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DUF4407 PF14362.1 KPI44381.1 - 3.3 6.5 15.2 1.4 7.7 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GFA PF04828.9 KPI44382.1 - 0.00043 20.1 0.1 0.0013 18.6 0.0 1.8 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Pyr_redox_3 PF13738.1 KPI44383.1 - 3.2e-15 56.7 0.0 2e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI44383.1 - 5.2e-10 38.1 0.6 1.9e-08 32.9 0.0 2.5 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KPI44383.1 - 1.5e-09 38.0 0.0 0.00088 19.2 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI44383.1 - 1.2e-06 27.6 0.0 8.1e-05 21.6 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KPI44383.1 - 1.4e-06 28.2 0.0 9.1e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KPI44383.1 - 0.0024 17.6 0.3 0.44 10.2 0.0 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KPI44383.1 - 0.015 14.2 0.0 0.13 11.1 0.0 2.5 3 1 0 3 3 3 0 Lycopene cyclase protein DAO PF01266.19 KPI44383.1 - 0.016 14.1 0.0 12 4.6 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pkinase PF00069.20 KPI44384.1 - 7.5e-06 25.2 0.0 7.8e-05 21.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Ribosomal_S27 PF01599.14 KPI44385.1 - 1.9e-27 94.8 3.6 3.9e-27 93.8 2.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 KPI44385.1 - 9.5e-21 72.9 0.1 1.9e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KPI44385.1 - 2.6e-10 39.8 0.0 5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 KPI44385.1 - 0.0076 16.1 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 KPI44385.1 - 0.054 13.3 0.5 0.084 12.7 0.4 1.3 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 KPI44385.1 - 0.078 13.0 0.2 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) FA_desaturase PF00487.19 KPI44386.1 - 1.6e-33 116.2 16.4 4.3e-32 111.5 11.4 2.1 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KPI44386.1 - 4.8e-11 42.2 0.0 9.7e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BTB PF00651.26 KPI44387.1 - 3.1e-06 27.1 0.0 6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MRJP PF03022.11 KPI44390.1 - 3.1e-32 111.9 0.0 4.2e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.7 KPI44390.1 - 2.1e-05 24.0 0.2 6.2e-05 22.4 0.1 1.9 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region PIR PF00399.14 KPI44390.1 - 7.1e-05 22.0 4.7 0.00019 20.6 3.2 1.8 1 0 0 1 1 1 1 Yeast PIR protein repeat NHL PF01436.16 KPI44390.1 - 0.0076 16.1 2.6 7.1 6.7 0.0 4.2 4 0 0 4 4 4 1 NHL repeat PD40 PF07676.7 KPI44390.1 - 0.0085 15.7 0.3 0.03 13.9 0.1 2.1 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Reg_prop PF07494.6 KPI44390.1 - 0.17 11.9 1.9 71 3.9 0.0 4.3 4 0 0 4 4 4 0 Two component regulator propeller PQQ_3 PF13570.1 KPI44390.1 - 2.5 8.4 8.3 33 4.9 0.1 4.5 5 0 0 5 5 5 0 PQQ-like domain Fungal_trans PF04082.13 KPI44391.1 - 1.3e-19 70.1 2.5 1.3e-19 70.1 1.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.21 KPI44391.1 - 1.3e-15 57.1 0.0 2.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 KPI44391.1 - 0.0059 16.8 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.22 KPI44391.1 - 0.018 15.4 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.1 KPI44391.1 - 0.02 15.7 0.0 0.058 14.2 0.0 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase F420_oxidored PF03807.12 KPI44391.1 - 0.073 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.14 KPI44391.1 - 0.11 11.5 0.1 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain BPL_LplA_LipB PF03099.14 KPI44392.1 - 6.1e-11 42.4 0.1 4.9e-10 39.5 0.0 2.3 2 1 0 2 2 2 1 Biotin/lipoate A/B protein ligase family Ytp1 PF10355.4 KPI44393.1 - 5.2e-108 360.3 9.6 9e-108 359.5 6.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KPI44393.1 - 3.5e-29 100.4 9.5 3.5e-29 100.4 6.6 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF1129 PF06570.6 KPI44393.1 - 0.86 8.8 12.0 0.23 10.7 2.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Sec7 PF01369.15 KPI44394.1 - 1.2e-38 132.6 0.0 2.5e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KPI44394.1 - 1.5e-16 60.6 0.0 5.4e-16 58.8 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain ADH_zinc_N_2 PF13602.1 KPI44396.1 - 3.5e-17 63.4 0.0 1.5e-16 61.4 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KPI44396.1 - 2.9e-06 26.8 0.0 7.4e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI44396.1 - 0.0015 18.2 0.2 0.015 15.0 0.0 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain LsmAD PF06741.8 KPI44398.1 - 2e-24 85.4 7.2 5.4e-24 84.0 5.0 1.8 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 KPI44398.1 - 2e-11 43.6 0.0 5.6e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain SAD_SRA PF02182.12 KPI44399.1 - 1.9e-19 69.4 0.0 4.5e-19 68.2 0.0 1.6 1 1 0 1 1 1 1 SAD/SRA domain zf-MIZ PF02891.15 KPI44401.1 - 2.4e-09 36.5 0.6 4.5e-09 35.6 0.4 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PemK PF02452.12 KPI44401.1 - 0.01 16.0 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 PemK-like protein zf-Nse PF11789.3 KPI44401.1 - 0.025 14.0 0.2 0.054 13.0 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Trehalase PF01204.13 KPI44403.1 - 1.2e-171 571.8 0.2 1.9e-171 571.2 0.2 1.2 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 KPI44403.1 - 1.4e-12 46.7 1.2 2.2e-12 46.0 0.8 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain GRIM-19 PF06212.7 KPI44404.1 - 1e-19 70.5 0.0 2.3e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 GRIM-19 protein adh_short PF00106.20 KPI44404.1 - 6.3e-17 61.9 0.3 9.6e-17 61.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI44404.1 - 2e-07 31.0 0.1 6.8e-07 29.3 0.0 2.0 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI44404.1 - 2.9e-06 27.0 0.1 5e-06 26.2 0.1 1.5 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.13 KPI44404.1 - 0.0032 17.4 0.1 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain DUF460 PF04312.8 KPI44404.1 - 0.021 14.3 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF460) 14-3-3 PF00244.15 KPI44405.1 - 2.6e-115 383.4 8.2 3.3e-115 383.1 5.7 1.1 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 KPI44405.1 - 0.0099 15.7 1.0 0.021 14.7 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TerB PF05099.8 KPI44405.1 - 0.044 13.5 0.8 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 Tellurite resistance protein TerB HisKA PF00512.20 KPI44405.1 - 0.067 13.2 1.7 5.7 7.0 0.0 2.9 2 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain RhoGAP PF00620.22 KPI44406.1 - 1.3e-46 157.9 0.0 2.9e-46 156.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 KPI44406.1 - 4.4e-14 52.4 0.2 1.4e-13 50.8 0.1 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain MADF_DNA_bdg PF10545.4 KPI44406.1 - 0.031 14.4 2.8 0.086 13.0 1.7 2.0 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4407 PF14362.1 KPI44406.1 - 6.5 5.6 8.1 11 4.8 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gaa1 PF04114.9 KPI44409.1 - 1.7e-94 317.3 8.9 1e-93 314.7 6.1 1.9 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component TRAM_LAG1_CLN8 PF03798.11 KPI44410.1 - 2.1e-37 128.6 18.5 9.2e-36 123.2 9.5 2.4 1 1 1 2 2 2 2 TLC domain DUF1500 PF07389.7 KPI44410.1 - 0.34 10.9 1.8 1.1 9.3 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1500) PAP2_3 PF14378.1 KPI44412.1 - 1.3e-19 70.4 11.4 7.9e-15 54.8 3.0 2.3 2 0 0 2 2 2 2 PAP2 superfamily XPG_I PF00867.13 KPI44413.1 - 1.8e-24 85.5 0.1 4.3e-24 84.3 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KPI44413.1 - 2.2e-20 72.8 0.0 4.9e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 KPI44413.1 - 0.0023 17.4 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing adh_short PF00106.20 KPI44414.1 - 4.2e-13 49.5 0.1 7.2e-13 48.7 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI44414.1 - 0.0095 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 KR domain APH PF01636.18 KPI44416.1 - 2.9e-22 79.5 0.0 5.2e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KPI44416.1 - 0.002 17.7 0.1 0.0042 16.6 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KPI44416.1 - 0.11 11.4 0.1 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase VSG_B PF13206.1 KPI44417.1 - 0.057 12.5 0.1 0.48 9.5 0.1 2.2 2 0 0 2 2 2 0 Trypanosomal VSG domain PDE6_gamma PF04868.7 KPI44417.1 - 0.096 12.5 0.0 0.42 10.4 0.0 2.1 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit SUR7 PF06687.7 KPI44419.1 - 2.5e-34 118.6 2.3 3.1e-34 118.4 1.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KPI44419.1 - 6.1e-07 29.2 11.8 6.1e-07 29.2 8.2 2.0 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 KPI44419.1 - 0.00017 20.8 1.0 0.00029 20.1 0.7 1.4 1 0 0 1 1 1 1 Clc-like Amastin PF07344.6 KPI44419.1 - 0.0012 18.5 7.6 0.0019 17.7 5.2 1.3 1 0 0 1 1 1 1 Amastin surface glycoprotein Fig1 PF12351.3 KPI44419.1 - 0.0024 17.7 0.3 0.0024 17.7 0.2 1.6 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 PMP22_Claudin PF00822.15 KPI44419.1 - 0.008 15.8 6.1 0.016 14.8 4.2 1.5 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF373 PF04123.8 KPI44419.1 - 0.058 12.3 0.5 0.096 11.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF4064 PF13273.1 KPI44419.1 - 0.42 10.7 0.1 0.42 10.7 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Claudin_3 PF06653.6 KPI44419.1 - 9.6 5.9 13.6 4.7 6.9 6.5 2.3 2 1 1 3 3 3 0 Tight junction protein, Claudin-like Fungal_trans PF04082.13 KPI44420.1 - 8.2e-33 113.3 0.5 1.2e-32 112.7 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 KPI44421.1 - 7.3e-50 169.3 0.0 8.5e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_M16 PF00675.15 KPI44422.1 - 7.5e-58 194.5 0.0 3.8e-57 192.2 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KPI44422.1 - 1.9e-42 145.0 0.0 2.6e-41 141.3 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M20 PF01546.23 KPI44423.1 - 9.3e-31 106.8 0.0 2e-30 105.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KPI44423.1 - 1.2e-15 57.2 0.0 2.1e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Chromo PF00385.19 KPI44424.1 - 0.025 14.2 0.3 0.047 13.3 0.2 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain p450 PF00067.17 KPI44426.1 - 6.1e-14 51.4 0.1 7.5e-12 44.5 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 HORMA PF02301.13 KPI44427.1 - 4.8e-47 160.1 0.2 5.4e-47 159.9 0.1 1.0 1 0 0 1 1 1 1 HORMA domain Alba PF01918.16 KPI44427.1 - 0.018 14.6 0.5 0.023 14.2 0.3 1.5 1 1 0 1 1 1 0 Alba TAF PF02969.12 KPI44427.1 - 0.077 12.9 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) LemA PF04011.7 KPI44427.1 - 0.083 11.9 0.2 0.15 11.1 0.2 1.4 1 0 0 1 1 1 0 LemA family DUF2411 PF10304.4 KPI44427.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) DUF1917 PF08939.5 KPI44428.1 - 4.3e-63 213.2 0.6 5.5e-63 212.9 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) V-SNARE_C PF12352.3 KPI44428.1 - 0.032 14.3 0.3 0.11 12.5 0.1 2.0 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Iso_dh PF00180.15 KPI44430.1 - 8.7e-126 419.5 0.0 9.9e-126 419.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RabGAP-TBC PF00566.13 KPI44431.1 - 9.5e-34 116.7 0.0 1.4e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain tRNA-synt_1 PF00133.17 KPI44432.1 - 1.2e-50 172.2 0.0 6e-30 103.8 0.0 5.8 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 KPI44432.1 - 3e-36 124.4 0.0 4.5e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 KPI44432.1 - 1.1e-27 96.7 0.0 1.1e-20 73.7 0.0 4.0 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KPI44432.1 - 1.3e-08 34.7 0.0 2.9e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KPI44432.1 - 0.0045 16.1 0.0 0.21 10.6 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 KPI44432.1 - 0.026 13.3 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (R) Lar_restr_allev PF14354.1 KPI44432.1 - 0.083 13.2 0.1 6.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar adh_short PF00106.20 KPI44433.1 - 5.1e-19 68.8 0.2 1.1e-18 67.7 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI44433.1 - 5.7e-07 29.5 0.0 8.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI44433.1 - 1.7e-05 24.5 0.5 5.1e-05 23.0 0.2 1.8 2 0 0 2 2 2 1 KR domain AdoHcyase_NAD PF00670.16 KPI44433.1 - 0.021 14.7 0.1 0.035 13.9 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.16 KPI44433.1 - 0.056 12.8 0.1 0.085 12.2 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KPI44433.1 - 0.085 12.6 0.2 1 9.1 0.1 2.6 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MFS_1 PF07690.11 KPI44434.1 - 5e-28 97.8 44.0 7.1e-28 97.3 30.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Kri1_C PF12936.2 KPI44435.1 - 1.6e-29 101.7 0.7 1.6e-29 101.7 0.5 4.6 5 1 1 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.7 KPI44435.1 - 3e-25 88.4 21.0 3e-25 88.4 14.6 4.6 5 2 0 5 5 5 1 KRI1-like family GPP34 PF05719.6 KPI44436.1 - 1.4e-64 217.9 0.1 1.8e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) HTH_23 PF13384.1 KPI44438.1 - 0.069 12.8 3.5 4.9 6.9 0.7 3.2 2 1 0 2 2 2 0 Homeodomain-like domain HTH_AraC PF00165.18 KPI44438.1 - 0.095 12.5 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_28 PF13518.1 KPI44438.1 - 0.27 11.2 2.8 3.4 7.7 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HLH PF00010.21 KPI44439.1 - 0.72 9.5 6.5 0.09 12.4 0.5 2.2 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain NST1 PF13945.1 KPI44439.1 - 4.5 7.2 8.9 0.77 9.7 2.5 1.9 2 0 0 2 2 2 0 Salt tolerance down-regulator Baculo_ME53 PF06061.6 KPI44440.1 - 0.3 10.0 2.3 0.38 9.6 1.6 1.1 1 0 0 1 1 1 0 Baculoviridae ME53 WW PF00397.21 KPI44441.1 - 9.6e-09 34.9 2.3 9.6e-09 34.9 1.6 2.1 2 0 0 2 2 2 1 WW domain DUF1192 PF06698.6 KPI44441.1 - 0.051 13.3 0.5 0.12 12.2 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) CENP-B_dimeris PF09026.5 KPI44441.1 - 0.2 11.9 4.4 0.43 10.8 3.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain COPI_C PF06957.6 KPI44441.1 - 0.94 7.9 9.2 5.4 5.4 3.0 2.1 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus FTHFS PF01268.14 KPI44442.1 - 6.5e-236 783.6 0.0 3.9e-234 777.8 0.0 2.1 1 1 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KPI44442.1 - 9.1e-70 232.8 1.5 9.1e-70 232.8 1.0 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KPI44442.1 - 4e-38 130.0 1.0 8e-38 129.0 0.7 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.22 KPI44442.1 - 0.0038 16.6 0.1 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DASH_Spc19 PF08287.6 KPI44443.1 - 8.7e-46 155.3 0.7 1.1e-45 155.0 0.5 1.1 1 0 0 1 1 1 1 Spc19 RTX PF02382.10 KPI44443.1 - 0.076 11.2 0.2 0.093 10.9 0.1 1.1 1 0 0 1 1 1 0 RTX N-terminal domain rRNA_processing PF08524.6 KPI44443.1 - 0.66 9.7 6.1 1.4 8.7 0.9 2.2 2 1 0 2 2 2 0 rRNA processing DUF536 PF04394.9 KPI44443.1 - 4.6 7.0 11.9 2.4 7.9 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function, DUF536 Scs3p PF10261.4 KPI44444.1 - 1.5e-20 73.2 3.0 2.1e-20 72.8 2.1 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM HlyIII PF03006.15 KPI44446.1 - 9.2e-45 152.7 11.2 1.1e-44 152.4 7.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF4401 PF14351.1 KPI44446.1 - 0.005 15.8 8.6 0.2 10.6 1.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4401) DUF3325 PF11804.3 KPI44446.1 - 0.31 10.9 9.2 0.064 13.1 3.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3325) KH_1 PF00013.24 KPI44447.1 - 5.1e-40 134.9 9.5 7.3e-16 57.5 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KPI44447.1 - 1.3e-30 104.4 12.5 8.1e-12 44.5 0.9 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KPI44447.1 - 1.2e-10 40.7 9.2 0.0044 16.5 0.5 3.5 3 1 0 3 3 3 3 KH domain KH_4 PF13083.1 KPI44447.1 - 2.3e-09 36.7 4.5 0.0088 15.6 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KPI44447.1 - 0.00031 20.4 5.1 0.32 10.8 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 KPI44447.1 - 0.0036 16.7 0.1 0.77 9.2 0.0 3.1 3 0 0 3 3 3 1 dUTPase DUF4231 PF14015.1 KPI44448.1 - 0.073 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) SPW PF03779.9 KPI44448.1 - 0.12 11.7 2.5 0.25 10.7 1.7 1.6 1 1 0 1 1 1 0 SPW repeat VIT1 PF01988.14 KPI44448.1 - 2.1 7.7 7.5 1.7 8.0 1.9 2.1 1 1 1 2 2 2 0 VIT family Vac_ImportDeg PF09783.4 KPI44449.1 - 5.8e-30 104.0 0.0 8.2e-29 100.3 0.0 2.2 1 1 0 1 1 1 1 Vacuolar import and degradation protein Tfb2 PF03849.9 KPI44451.1 - 1.4e-115 385.8 0.0 1.8e-115 385.4 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KPI44451.1 - 0.00028 20.6 0.0 0.00058 19.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 4HBT_3 PF13622.1 KPI44452.1 - 1.4e-31 110.1 0.1 1.8e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KPI44452.1 - 0.00085 18.9 0.1 0.0022 17.6 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA thioesterase CitT PF12431.3 KPI44453.1 - 0.072 13.1 0.3 0.23 11.5 0.2 1.9 1 0 0 1 1 1 0 Transcriptional regulator Fungal_trans PF04082.13 KPI44454.1 - 1.6e-25 89.4 0.2 2.5e-25 88.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 KPI44454.1 - 5.1e-17 61.9 0.0 2e-12 46.8 0.0 2.8 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 KPI44454.1 - 1.9e-08 33.6 0.1 0.001 18.0 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI44454.1 - 6.7e-07 28.5 1.1 7.9e-06 24.9 0.9 2.1 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KPI44454.1 - 9e-06 25.6 0.8 2.7e-05 24.0 0.1 2.2 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI44454.1 - 0.00028 20.8 0.1 0.00067 19.5 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI44454.1 - 0.0023 16.9 0.1 0.008 15.1 0.1 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Zn_clus PF00172.13 KPI44454.1 - 0.0042 16.9 0.5 0.011 15.6 0.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HI0933_like PF03486.9 KPI44454.1 - 0.0058 15.1 0.1 0.0089 14.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KPI44454.1 - 0.0082 16.5 0.3 0.017 15.5 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI44454.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI44454.1 - 0.023 13.5 0.2 0.036 12.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KPI44454.1 - 0.069 12.7 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KPI44454.1 - 0.07 12.2 2.5 0.041 12.9 0.3 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 KPI44454.1 - 0.19 10.7 0.2 0.32 10.0 0.1 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 KPI44455.1 - 2.4e-94 316.3 0.0 3e-94 316.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KPI44455.1 - 5.5e-05 23.1 0.1 0.00011 22.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI44455.1 - 0.0009 18.2 0.2 0.0023 16.8 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI44455.1 - 0.0099 15.8 0.2 0.026 14.5 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KPI44455.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 KPI44455.1 - 0.024 14.6 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.17 KPI44455.1 - 0.035 12.9 0.1 0.048 12.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KPI44455.1 - 0.048 12.4 0.4 0.091 11.5 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.13 KPI44455.1 - 0.072 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 KPI44455.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 ThiF family ArsA_ATPase PF02374.10 KPI44457.1 - 9.1e-96 320.4 0.0 1e-95 320.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KPI44457.1 - 7e-05 22.3 0.0 0.00043 19.7 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KPI44457.1 - 0.13 12.1 0.0 0.76 9.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain BRE1 PF08647.6 KPI44458.1 - 2.2e-23 82.0 15.6 2.2e-23 82.0 10.8 6.5 5 1 1 6 6 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 KPI44458.1 - 3.4e-06 26.9 11.1 6e-06 26.1 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KPI44458.1 - 3.5e-06 26.5 10.1 6.3e-06 25.7 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI44458.1 - 8.1e-06 25.4 11.7 1.5e-05 24.5 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI44458.1 - 0.00018 21.1 11.0 0.00035 20.2 7.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KPI44458.1 - 0.0014 18.4 8.9 0.0028 17.4 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 KPI44458.1 - 0.002 17.6 4.1 0.0045 16.5 2.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 KPI44458.1 - 0.011 15.4 5.0 0.037 13.7 3.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 KPI44458.1 - 0.081 12.7 4.0 0.16 11.7 2.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KPI44458.1 - 0.093 12.3 5.1 0.22 11.1 3.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 KPI44458.1 - 0.16 11.4 0.0 0.16 11.4 0.0 4.6 4 0 0 4 4 4 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.1 KPI44458.1 - 0.34 10.8 8.2 0.7 9.8 5.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING IncA PF04156.9 KPI44458.1 - 0.51 9.9 80.8 0.31 10.5 13.5 5.9 1 1 3 4 4 3 0 IncA protein Filament PF00038.16 KPI44458.1 - 3.2 7.1 79.3 3.2 7.1 3.5 5.0 2 1 1 4 4 4 0 Intermediate filament protein DUF2370 PF10176.4 KPI44460.1 - 2.8e-79 265.7 0.0 4.6e-79 265.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) ELYS PF13934.1 KPI44462.1 - 2.4e-56 191.0 2.2 2.9e-56 190.7 1.5 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly DUF4274 PF14096.1 KPI44462.1 - 0.0061 16.3 0.1 0.018 14.8 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4274) PAP2 PF01569.16 KPI44464.1 - 1.8e-19 69.6 1.3 1.8e-19 69.6 0.9 1.7 2 0 0 2 2 2 1 PAP2 superfamily Thia_YuaJ PF09515.5 KPI44464.1 - 0.29 10.8 3.5 2.8 7.6 2.5 2.2 1 1 0 1 1 1 0 Thiamine transporter protein (Thia_YuaJ) TctB PF07331.6 KPI44464.1 - 2 8.0 7.7 93 2.6 4.0 3.2 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family Zip PF02535.17 KPI44466.1 - 3.8e-49 167.4 0.4 7.4e-49 166.4 0.3 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter DAP10 PF07213.6 KPI44466.1 - 0.24 11.1 2.4 0.3 10.8 0.3 2.1 2 0 0 2 2 2 0 DAP10 membrane protein BTB PF00651.26 KPI44467.1 - 6.3e-11 42.2 0.0 4.2e-10 39.5 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain FMO-like PF00743.14 KPI44468.1 - 1.9e-53 181.5 0.0 3.7e-53 180.5 0.0 1.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KPI44468.1 - 3.2e-17 63.2 0.0 1.7e-16 60.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI44468.1 - 1.5e-07 31.5 0.0 2.5e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI44468.1 - 2.6e-05 23.3 0.0 6.5e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KPI44468.1 - 4.1e-05 23.4 0.1 0.0016 18.2 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KPI44468.1 - 0.0007 19.5 0.0 0.003 17.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 KPI44468.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain COX5A PF02284.11 KPI44469.1 - 2.4e-40 136.8 0.1 3.5e-40 136.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DHC_N1 PF08385.7 KPI44469.1 - 0.16 10.3 0.1 0.39 9.0 0.0 1.5 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 GMC_oxred_N PF00732.14 KPI44470.1 - 4.2e-59 200.1 0.0 5.8e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI44470.1 - 2.3e-39 134.9 0.0 4.5e-39 134.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KPI44470.1 - 4.3e-05 22.6 0.0 6.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KPI44470.1 - 0.0005 20.0 0.0 0.0015 18.4 0.0 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI44470.1 - 0.00088 18.2 0.1 0.031 13.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KPI44470.1 - 0.016 14.3 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KPI44470.1 - 0.025 14.6 0.1 1.2 9.1 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI44470.1 - 0.046 12.6 0.0 0.15 10.9 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.13 KPI44470.1 - 0.15 12.0 0.1 0.62 10.0 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.9 KPI44470.1 - 0.18 10.2 0.0 0.25 9.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein MACPF PF01823.14 KPI44471.1 - 6.9e-16 58.5 6.1 1.2e-15 57.8 3.6 1.8 1 1 1 2 2 2 2 MAC/Perforin domain MFS_2 PF13347.1 KPI44472.1 - 9.4e-08 30.8 11.3 7.8e-07 27.8 5.7 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein DSPc PF00782.15 KPI44473.1 - 7e-20 70.9 0.0 3e-17 62.4 0.0 2.3 1 1 1 2 2 2 2 Dual specificity phosphatase, catalytic domain DUF2422 PF10337.4 KPI44474.1 - 3.5e-60 204.0 0.7 8e-60 202.9 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 KPI44474.1 - 1e-12 48.0 13.6 1e-12 48.0 9.4 3.4 2 1 0 3 3 3 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 KPI44474.1 - 1.1e-10 41.5 0.0 3.1e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2421) Fungal_trans_2 PF11951.3 KPI44475.1 - 0.0036 15.9 1.4 0.035 12.6 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain CLTH PF10607.4 KPI44476.1 - 6.1e-27 94.0 0.3 1.1e-26 93.2 0.2 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KPI44476.1 - 2.2e-18 65.6 0.8 4.6e-18 64.6 0.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 KPI44476.1 - 6.4e-05 22.2 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 KPI44476.1 - 0.00015 21.4 0.3 0.00026 20.7 0.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KPI44476.1 - 0.001 18.7 0.2 0.0018 17.9 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KPI44476.1 - 0.0032 17.4 0.6 0.0054 16.7 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KPI44476.1 - 0.0071 16.2 0.9 0.014 15.2 0.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KPI44476.1 - 0.0077 15.8 0.3 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI44476.1 - 0.029 14.0 0.5 0.052 13.2 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LisH PF08513.6 KPI44476.1 - 0.035 13.8 1.9 0.096 12.4 0.1 2.3 2 0 0 2 2 2 0 LisH MFS_1 PF07690.11 KPI44477.1 - 5.2e-21 74.7 28.7 6.9e-19 67.7 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KPI44477.1 - 0.012 13.6 0.0 0.068 11.2 0.0 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KPI44478.1 - 3.1e-19 68.8 34.5 2.1e-13 49.7 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI44478.1 - 1.1e-10 40.6 21.6 2.6e-10 39.4 2.8 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter Ni_hydr_CYTB PF01292.15 KPI44478.1 - 0.00023 20.5 1.2 0.00023 20.5 0.8 2.2 2 0 0 2 2 2 1 Prokaryotic cytochrome b561 Cytochrom_B_N PF00033.14 KPI44478.1 - 0.0021 17.4 0.5 0.0021 17.4 0.4 2.7 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Tyr-DNA_phospho PF06087.7 KPI44479.1 - 1.1e-44 152.7 0.0 1.4e-43 149.1 0.0 2.1 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.15 KPI44479.1 - 0.0001 21.5 4.1 0.0015 17.9 0.2 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif PLDc_2 PF13091.1 KPI44479.1 - 0.13 12.0 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 PLD-like domain COesterase PF00135.23 KPI44480.1 - 9.1e-91 305.1 0.2 1.8e-83 281.0 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI44480.1 - 3.8e-07 29.9 0.3 8e-07 28.8 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 KPI44480.1 - 0.049 12.8 0.1 0.081 12.1 0.1 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 KPI44480.1 - 0.055 13.2 0.8 0.083 12.6 0.5 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family zf-met PF12874.2 KPI44481.1 - 8.1e-09 35.3 0.6 1.9e-08 34.1 0.4 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KPI44481.1 - 1.9e-08 34.2 0.6 1.9e-08 34.2 0.4 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.7 KPI44481.1 - 0.0032 17.1 0.1 0.0091 15.6 0.1 1.8 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_2 PF12756.2 KPI44481.1 - 0.06 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KPI44481.1 - 0.12 12.7 0.4 0.23 11.8 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1764 PF08576.5 KPI44481.1 - 3.8 8.3 11.8 16 6.3 0.2 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Acatn PF13000.2 KPI44482.1 - 2e-124 416.1 24.2 8.8e-75 252.2 7.5 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Peptidase_C65 PF10275.4 KPI44483.1 - 1.1e-45 155.9 0.0 1.3e-31 109.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase C65 Otubain DUF605 PF04652.11 KPI44483.1 - 0.25 10.7 19.1 0.35 10.2 13.2 1.2 1 0 0 1 1 1 0 Vta1 like KOW PF00467.24 KPI44484.1 - 0.15 11.8 0.8 0.3 10.8 0.5 1.5 1 0 0 1 1 1 0 KOW motif Kinesin PF00225.18 KPI44487.1 - 2.8e-84 282.6 0.5 2.8e-84 282.6 0.3 1.8 2 0 0 2 2 2 1 Kinesin motor domain HHH PF00633.18 KPI44487.1 - 0.0095 15.5 0.3 0.39 10.5 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 KPI44487.1 - 0.043 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF45 PF01863.12 KPI44487.1 - 0.071 12.8 1.2 0.14 11.9 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF45 V_ATPase_I PF01496.14 KPI44487.1 - 8.3 4.1 4.9 12 3.6 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PP28 PF10252.4 KPI44489.1 - 3.5e-28 97.4 22.1 3.5e-28 97.4 15.3 3.1 3 0 0 3 3 3 2 Casein kinase substrate phosphoprotein PP28 EI24 PF07264.6 KPI44490.1 - 1.4e-06 27.9 3.9 3.4e-06 26.6 2.7 1.8 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) CBS PF00571.23 KPI44491.1 - 5.4e-20 70.9 6.4 4.5e-06 26.3 0.2 5.3 5 0 0 5 5 5 5 CBS domain DNA_pol_phi PF04931.8 KPI44492.1 - 0.12 10.1 0.0 0.15 9.8 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi NAD4L PF06235.6 KPI44492.1 - 0.14 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 NADH dehydrogenase subunit 4L (NAD4L) Glyco_hydro_3 PF00933.16 KPI44493.1 - 1.9e-54 184.6 0.0 2.8e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KPI44493.1 - 4.7e-30 104.8 0.0 8e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KPI44493.1 - 2.9e-07 30.3 0.0 6.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Pkinase PF00069.20 KPI44494.1 - 1.2e-74 250.7 0.0 1.7e-74 250.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI44494.1 - 8.5e-39 133.1 0.0 1.4e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KPI44494.1 - 2.8e-12 45.8 0.1 4.4e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 KPI44494.1 - 1.5e-06 27.4 0.0 2.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KPI44494.1 - 0.00014 20.9 0.0 0.0005 19.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KPI44494.1 - 0.0008 19.2 0.1 0.14 11.8 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KPI44494.1 - 0.0031 16.8 0.1 0.0079 15.5 0.0 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 KPI44494.1 - 0.097 12.0 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.6 KPI44494.1 - 0.11 11.6 0.1 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.15 KPI44494.1 - 0.25 10.8 0.1 0.45 10.0 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MAM33 PF02330.11 KPI44495.1 - 1.3e-23 83.8 0.4 1.3e-17 64.2 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial glycoprotein Senescence PF06911.7 KPI44499.1 - 0.034 13.8 0.8 0.067 12.8 0.6 1.5 1 0 0 1 1 1 0 Senescence-associated protein Methyltransf_23 PF13489.1 KPI44500.1 - 7.1e-17 61.6 0.1 9.8e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI44500.1 - 6.2e-07 29.1 0.0 2.6e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI44500.1 - 1.3e-06 28.9 0.0 2.6e-05 24.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI44500.1 - 2.3e-05 24.7 0.0 4.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI44500.1 - 5.1e-05 23.5 0.0 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KPI44500.1 - 0.00095 19.1 0.0 0.0025 17.8 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 KPI44500.1 - 0.0043 16.2 0.0 0.0072 15.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 KPI44500.1 - 0.022 14.1 0.0 0.064 12.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.7 KPI44500.1 - 0.03 14.8 0.0 0.25 11.8 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KPI44500.1 - 0.064 13.2 0.0 0.33 10.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 KPI44500.1 - 0.071 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 KPI44500.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Zn_clus PF00172.13 KPI44501.1 - 3.7e-08 33.1 9.6 6.5e-08 32.3 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KPI44501.1 - 0.0024 16.7 0.3 0.0041 16.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CorA PF01544.13 KPI44502.1 - 8.4e-06 25.0 5.5 4.7e-05 22.5 3.8 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein HisKA PF00512.20 KPI44502.1 - 0.056 13.4 0.2 0.14 12.1 0.2 1.7 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain DUF342 PF03961.8 KPI44502.1 - 0.14 10.5 1.2 0.21 9.9 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) GTP_EFTU PF00009.22 KPI44503.1 - 3.1e-46 157.1 0.0 4.9e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KPI44503.1 - 1.8e-36 124.2 4.2 2.9e-36 123.6 2.9 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KPI44503.1 - 1.4e-20 72.9 0.0 2.4e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KPI44503.1 - 0.00013 21.9 0.1 0.00031 20.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KPI44503.1 - 0.00024 21.0 0.0 0.00054 19.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KPI44503.1 - 0.00041 19.7 0.0 0.00088 18.6 0.0 1.5 1 0 0 1 1 1 1 Ras family EFG_II PF14492.1 KPI44503.1 - 0.0019 18.0 0.0 0.0054 16.5 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 KPI44503.1 - 0.006 15.8 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ChAPs PF09295.5 KPI44505.1 - 2.8e-152 507.0 0.0 3.9e-152 506.5 0.0 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 KPI44505.1 - 1.5e-07 30.9 1.0 0.02 14.5 0.0 3.4 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 KPI44505.1 - 0.00013 21.7 0.6 1.9 8.5 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KPI44505.1 - 0.00025 21.4 0.7 1 10.2 0.0 4.6 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KPI44505.1 - 0.0011 18.7 3.3 0.12 12.3 0.7 3.2 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KPI44505.1 - 0.0019 17.8 1.8 1.6 8.7 0.3 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KPI44505.1 - 0.0057 16.9 0.3 0.81 10.0 0.0 3.0 2 1 2 4 4 4 1 Tetratricopeptide repeat YejG PF13989.1 KPI44505.1 - 0.013 15.5 0.1 0.072 13.1 0.0 2.2 2 0 0 2 2 2 0 YejG-like protein TPR_1 PF00515.23 KPI44505.1 - 0.014 15.0 1.7 3.5 7.4 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 KPI44505.1 - 0.021 13.8 7.5 0.17 10.9 0.5 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat CH PF00307.26 KPI44505.1 - 0.034 14.2 0.2 0.087 12.8 0.1 1.7 1 0 0 1 1 1 0 Calponin homology (CH) domain 14-3-3 PF00244.15 KPI44507.1 - 7.1e-09 35.0 0.0 1.7e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 14-3-3 protein DUF605 PF04652.11 KPI44507.1 - 6.5 6.0 18.7 0.36 10.1 2.7 2.1 2 0 0 2 2 2 0 Vta1 like YccV-like PF08755.6 KPI44508.1 - 4.6e-20 71.4 0.1 1.6e-19 69.6 0.0 1.9 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like F-box-like PF12937.2 KPI44508.1 - 5.5e-09 35.6 0.8 1.3e-08 34.4 0.5 1.7 1 0 0 1 1 1 1 F-box-like Transglut_core2 PF13369.1 KPI44508.1 - 1.1e-08 34.6 0.0 2.4e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box PF00646.28 KPI44508.1 - 2.1e-06 27.2 0.0 4.8e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 KPI44508.1 - 0.0029 17.9 0.1 0.0056 17.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box-like_2 PF13013.1 KPI44508.1 - 0.071 12.8 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 F-box-like domain IBR PF01485.16 KPI44510.1 - 1.5e-11 43.9 45.2 1.8e-06 27.6 10.9 3.8 3 1 0 3 3 3 2 IBR domain FIVAR PF07554.8 KPI44510.1 - 0.0052 16.9 1.0 0.11 12.7 0.1 2.6 2 0 0 2 2 2 1 Uncharacterised Sugar-binding Domain zf-CCHC_2 PF13696.1 KPI44510.1 - 0.053 13.0 0.2 0.053 13.0 0.1 3.6 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC PF00098.18 KPI44510.1 - 0.066 13.1 0.6 0.066 13.1 0.4 4.4 5 0 0 5 5 5 0 Zinc knuckle NAD_binding_6 PF08030.7 KPI44511.1 - 3.3e-15 56.3 0.0 8.9e-10 38.6 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KPI44511.1 - 6.1e-14 51.7 0.0 2.7e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain Ferric_reduct PF01794.14 KPI44511.1 - 1.2e-13 51.2 8.9 1.2e-13 51.2 6.2 2.2 2 1 0 2 2 2 1 Ferric reductase like transmembrane component Acetyltransf_1 PF00583.19 KPI44512.1 - 2.9e-12 46.4 0.0 4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI44512.1 - 6.9e-08 32.5 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KPI44512.1 - 0.0002 21.2 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KPI44512.1 - 0.0023 18.1 0.0 0.0028 17.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI44512.1 - 0.0048 16.9 0.0 0.0069 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KPI44512.1 - 0.022 14.5 0.1 0.035 13.8 0.1 1.2 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 KPI44512.1 - 0.023 14.5 0.1 0.076 12.8 0.1 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 KPI44512.1 - 0.024 15.1 0.0 0.073 13.6 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KPI44512.1 - 0.039 13.8 0.0 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Myb_DNA-binding PF00249.26 KPI44514.1 - 0.002 18.1 0.2 0.0057 16.6 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain AMP-binding PF00501.23 KPI44515.1 - 5.6e-22 77.7 0.0 9.3e-21 73.6 0.0 1.9 2 0 0 2 2 2 2 AMP-binding enzyme Oxysterol_BP PF01237.13 KPI44516.1 - 1.6e-52 178.1 0.0 9.3e-52 175.6 0.0 1.9 1 1 0 1 1 1 1 Oxysterol-binding protein 5_nucleotid_C PF02872.13 KPI44516.1 - 0.078 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Mo25 PF08569.6 KPI44518.1 - 1.3e-21 77.0 0.0 1.6e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 Mo25-like LysM PF01476.15 KPI44519.1 - 8.1e-09 35.2 0.0 1.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 LysM domain Fructosamin_kin PF03881.9 KPI44520.1 - 1.9e-68 230.5 0.0 5.4e-68 229.0 0.0 1.6 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KPI44520.1 - 2e-06 27.7 0.0 3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KPI44520.1 - 0.022 13.4 0.0 0.032 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DEAD PF00270.24 KPI44521.1 - 8.1e-39 132.8 0.0 2.6e-38 131.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KPI44521.1 - 1.2e-22 79.1 0.4 2.2e-22 78.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KPI44521.1 - 9.7e-22 76.6 0.0 2.4e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Brix PF04427.13 KPI44522.1 - 3.2e-49 167.1 0.1 4.5e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Brix domain CCDC-167 PF15188.1 KPI44522.1 - 0.57 10.1 4.4 1.1 9.2 0.8 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Cytochrom_B561 PF03188.11 KPI44523.1 - 1.7e-07 31.1 12.0 1.7e-07 31.1 8.3 1.6 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 Mpp10 PF04006.7 KPI44524.1 - 6.7e-74 249.3 64.0 3.6e-71 240.3 44.4 2.3 1 1 0 1 1 1 1 Mpp10 protein Fungal_trans PF04082.13 KPI44525.1 - 2.8e-15 55.9 3.0 4.7e-15 55.1 1.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI44525.1 - 5.7e-05 22.9 8.2 5.7e-05 22.9 5.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KPI44525.1 - 9.3e-05 22.5 3.6 0.00033 20.8 2.5 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI44525.1 - 0.00033 20.7 3.6 0.00033 20.7 2.5 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KPI44525.1 - 0.0061 16.4 1.2 0.0061 16.4 0.8 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 KPI44525.1 - 0.086 12.9 0.9 0.22 11.6 0.6 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KPI44525.1 - 0.2 11.8 1.1 0.73 10.0 0.8 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding GcpE PF04551.9 KPI44525.1 - 0.26 10.0 0.0 0.46 9.2 0.0 1.3 1 0 0 1 1 1 0 GcpE protein Pkinase PF00069.20 KPI44526.1 - 6.9e-38 130.2 0.0 1e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI44526.1 - 7.2e-30 103.9 0.0 1e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KPI44526.1 - 2.1e-05 24.3 0.4 0.041 13.6 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KPI44526.1 - 0.00019 20.5 0.0 0.00031 19.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KPI44526.1 - 0.00055 18.9 0.0 0.00085 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Annexin PF00191.15 KPI44527.1 - 7.1e-16 57.8 0.7 0.00011 22.0 0.0 4.5 4 0 0 4 4 4 3 Annexin G-patch PF01585.18 KPI44528.1 - 3.6e-09 36.2 1.6 3.6e-09 36.2 1.1 2.3 1 1 1 2 2 2 1 G-patch domain zf-RanBP PF00641.13 KPI44528.1 - 8.5e-09 34.3 4.1 1.5e-08 33.5 2.9 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KPI44528.1 - 3.5e-08 32.9 0.4 5.6e-05 22.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI44528.1 - 1.5e-06 28.0 0.1 0.00027 20.8 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 KPI44528.1 - 0.00021 21.0 1.7 0.00056 19.7 1.2 1.8 1 0 0 1 1 1 1 DExH-box splicing factor binding site RED_N PF07808.8 KPI44528.1 - 0.025 13.8 1.2 0.09 11.9 0.0 2.2 2 0 0 2 2 2 0 RED-like protein N-terminal region RRM_5 PF13893.1 KPI44528.1 - 0.033 14.0 0.3 3.5 7.5 0.1 2.8 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 KPI44529.1 - 9.4e-19 67.3 38.5 9.4e-19 67.3 26.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI44529.1 - 1.6e-08 33.5 7.2 1.6e-08 33.5 5.0 3.2 3 1 0 3 3 3 2 Sugar (and other) transporter GATA PF00320.22 KPI44530.1 - 3e-10 39.2 8.2 7.7e-10 37.9 5.7 1.7 1 0 0 1 1 1 1 GATA zinc finger Synaphin PF05835.7 KPI44530.1 - 2.7 8.1 13.4 1.6 8.8 4.8 2.4 2 0 0 2 2 2 0 Synaphin protein Glyco_transf_28 PF03033.15 KPI44531.1 - 8.2e-26 90.4 0.0 1.6e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 KPI44531.1 - 9.3e-25 85.9 0.7 2.7e-14 52.4 0.0 3.4 3 0 0 3 3 3 3 GRAM domain PH PF00169.24 KPI44531.1 - 1.3e-13 51.0 0.0 4.6e-13 49.2 0.0 2.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KPI44531.1 - 3.9e-07 30.3 0.0 1.2e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KPI44531.1 - 8.3e-05 22.4 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 PH domain UDPGT PF00201.13 KPI44531.1 - 0.00031 19.4 0.0 0.00048 18.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.1 KPI44531.1 - 0.0021 18.0 0.0 0.0082 16.1 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Rhomboid PF01694.17 KPI44532.1 - 5.2e-15 55.7 8.6 5.2e-15 55.7 6.0 1.9 1 1 1 2 2 2 1 Rhomboid family DUF1918 PF08940.6 KPI44533.1 - 0.0059 15.9 0.5 2.5 7.5 0.0 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF1918) I-set PF07679.11 KPI44533.1 - 0.12 12.2 0.0 1.5 8.7 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin I-set domain adh_short_C2 PF13561.1 KPI44534.1 - 5.8e-11 42.6 0.0 7.4e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI44534.1 - 2.5e-08 34.0 0.1 5.8e-08 32.8 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI44534.1 - 0.0017 18.0 0.0 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI44534.1 - 0.013 15.4 0.0 0.033 14.2 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding CybS PF05328.7 KPI44536.1 - 4.1e-46 155.8 0.0 4.7e-46 155.7 0.0 1.0 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 KPI44536.1 - 0.5 10.2 3.1 3.4 7.5 2.2 2.0 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Actin PF00022.14 KPI44538.1 - 1.2e-86 290.6 0.0 1.4e-86 290.4 0.0 1.1 1 0 0 1 1 1 1 Actin Cupin_1 PF00190.17 KPI44539.1 - 1.5e-10 40.6 0.0 2.3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 KPI44539.1 - 1.1e-05 24.8 0.0 1.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain RskA PF10099.4 KPI44539.1 - 0.068 12.8 0.2 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Mog1 PF04603.7 KPI44540.1 - 1.8e-16 60.3 0.1 5.9e-16 58.6 0.0 1.8 2 0 0 2 2 2 1 Ran-interacting Mog1 protein Aa_trans PF01490.13 KPI44541.1 - 4.6e-28 97.8 25.6 6e-28 97.4 17.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2101 PF09874.4 KPI44541.1 - 0.075 12.5 0.1 0.075 12.5 0.1 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) Flavin_Reduct PF01613.13 KPI44542.1 - 0.00036 20.4 0.0 0.00053 19.8 0.0 1.3 1 1 0 1 1 1 1 Flavin reductase like domain PCDO_beta_N PF12391.3 KPI44543.1 - 1.3 8.5 5.2 1.8 8.0 0.2 2.7 2 0 0 2 2 2 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal zf-PHD-like PF15446.1 KPI44544.1 - 1.1e-70 236.4 11.3 1.1e-70 236.4 7.8 1.8 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 KPI44544.1 - 6.6e-57 192.5 0.4 9.3e-57 192.0 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 KPI44544.1 - 3.6e-12 45.7 0.6 7.3e-12 44.6 0.4 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 KPI44544.1 - 3.8e-12 45.9 0.0 1.2e-11 44.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 KPI44544.1 - 2.2e-08 33.6 2.9 0.00034 20.2 0.7 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 KPI44544.1 - 4.1e-05 23.1 3.8 4.1e-05 23.1 2.6 3.7 3 2 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.1 KPI44544.1 - 0.0032 17.1 4.4 0.012 15.2 3.0 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KPI44544.1 - 0.005 16.1 3.8 0.005 16.1 2.7 3.1 3 1 0 3 3 3 1 PHD-finger DEAD PF00270.24 KPI44544.1 - 0.0061 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 KPI44544.1 - 0.022 14.1 0.1 0.065 12.6 0.0 1.8 1 0 0 1 1 1 0 DEAD_2 SnAC PF14619.1 KPI44544.1 - 0.029 14.5 0.4 0.029 14.5 0.3 3.6 4 0 0 4 4 4 0 Snf2-ATP coupling, chromatin remodelling complex PG_binding_1 PF01471.13 KPI44545.1 - 0.00023 21.0 0.1 0.21 11.6 0.0 3.3 2 1 0 2 2 2 2 Putative peptidoglycan binding domain MBOAT PF03062.14 KPI44546.1 - 3e-32 112.0 13.4 3e-32 112.0 9.3 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family NAD_binding_10 PF13460.1 KPI44546.1 - 0.066 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding MFS_1 PF07690.11 KPI44548.1 - 1.1e-34 119.7 51.3 1.6e-28 99.4 20.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peripla_BP_2 PF01497.13 KPI44549.1 - 0.028 13.5 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein DUF1192 PF06698.6 KPI44549.1 - 2.8 7.8 5.3 1.2 9.0 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TFR_dimer PF04253.10 KPI44550.1 - 3.5e-16 58.8 0.0 6.4e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 KPI44550.1 - 2e-07 30.6 0.3 4.1e-07 29.6 0.2 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M28 PF04389.12 KPI44550.1 - 0.00021 21.1 0.0 0.00046 19.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Folliculin PF11704.3 KPI44552.1 - 4e-41 140.3 0.0 7.8e-41 139.4 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport ELO PF01151.13 KPI44553.1 - 1.1e-63 214.9 21.4 1.3e-63 214.6 14.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PCI PF01399.22 KPI44554.1 - 2e-19 69.8 1.3 8.1e-19 67.8 0.2 2.4 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KPI44554.1 - 6.1e-07 29.3 0.1 1.7e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 KPI44554.1 - 0.013 15.2 0.9 5.9 6.9 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Ipi1_N PF12333.3 KPI44554.1 - 0.083 12.8 0.3 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation TPR_2 PF07719.12 KPI44554.1 - 0.26 11.2 3.0 4.1 7.5 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Cas_DxTHG PF09455.5 KPI44554.1 - 0.27 10.3 8.8 1.5 7.9 3.1 2.1 1 1 1 2 2 2 0 CRISPR-associated (Cas) DxTHG family Cnd1_N PF12922.2 KPI44556.1 - 1.2e-53 181.2 0.1 3.3e-53 179.8 0.1 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 KPI44556.1 - 2.5e-51 174.0 2.4 7.7e-48 162.6 0.0 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KPI44556.1 - 1.4e-12 47.7 0.6 0.00018 21.7 0.0 4.7 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 KPI44556.1 - 6.8e-09 35.0 8.3 0.026 14.5 0.0 6.9 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 KPI44556.1 - 4.3e-07 30.2 3.6 0.15 12.6 0.0 5.3 5 0 0 5 5 5 2 HEAT-like repeat Adaptin_N PF01602.15 KPI44556.1 - 7.6e-06 24.5 0.3 0.038 12.3 0.0 2.7 2 1 0 2 2 2 2 Adaptin N terminal region DUF2435 PF10363.4 KPI44556.1 - 0.0039 17.0 0.0 1.3 8.9 0.0 3.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) Cnd3 PF12719.2 KPI44556.1 - 0.39 9.6 6.4 1.9 7.3 1.1 3.6 2 2 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain Abhydrolase_5 PF12695.2 KPI44558.1 - 5.6e-09 35.9 0.0 8.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI44558.1 - 3e-08 33.8 0.0 1.4e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI44558.1 - 0.00075 19.1 0.0 0.0025 17.4 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KPI44558.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 KPI44558.1 - 0.0058 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S9 PF00326.16 KPI44558.1 - 0.0066 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIP PF03583.9 KPI44558.1 - 0.089 11.9 0.0 6.5 5.8 0.0 2.5 2 1 1 3 3 3 0 Secretory lipase Metallophos PF00149.23 KPI44559.1 - 3.5e-06 26.5 9.5 3e-05 23.5 6.6 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase COesterase PF00135.23 KPI44560.1 - 3.9e-67 227.1 0.0 9.8e-66 222.5 0.0 2.0 1 1 1 2 2 2 1 Carboxylesterase family FAD_binding_3 PF01494.14 KPI44560.1 - 2.1e-11 43.5 0.3 7.1e-06 25.2 0.1 2.9 3 0 0 3 3 3 2 FAD binding domain Abhydrolase_3 PF07859.8 KPI44560.1 - 1.2e-08 34.7 0.0 2.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold NAD_binding_8 PF13450.1 KPI44560.1 - 5.5e-05 23.1 0.1 0.00021 21.2 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI44560.1 - 0.00025 20.0 0.0 0.073 11.9 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KPI44560.1 - 0.0029 17.7 0.1 0.12 12.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI44560.1 - 0.0094 16.3 0.0 0.12 12.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase PSCyt2 PF07583.6 KPI44560.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) TrkA_N PF02254.13 KPI44560.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.10 KPI44560.1 - 0.17 11.7 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.9 KPI44560.1 - 0.2 11.5 0.1 0.86 9.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase S_100 PF01023.14 KPI44560.1 - 0.2 10.9 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Sox_C_TAD PF12067.3 KPI44561.1 - 0.32 11.1 9.1 0.59 10.2 6.3 1.5 1 1 0 1 1 1 0 Sox C-terminal transactivation domain RNA_polI_A34 PF08208.6 KPI44562.1 - 5.7e-12 45.7 0.5 5.7e-12 45.7 0.3 3.0 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 SAPS PF04499.10 KPI44562.1 - 0.39 9.3 2.4 0.38 9.3 1.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pneumo_att_G PF05539.6 KPI44562.1 - 2 7.7 8.6 3.6 6.8 5.9 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF4551 PF15087.1 KPI44562.1 - 4.8 5.4 6.6 6.7 4.9 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Lin-8 PF03353.10 KPI44562.1 - 8.5 5.5 10.4 16 4.6 7.2 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Myotub-related PF06602.9 KPI44563.1 - 1.5e-123 412.0 0.0 2.1e-123 411.6 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 KPI44563.1 - 0.014 15.6 0.0 0.047 13.9 0.0 1.8 1 1 0 1 1 1 0 Tyrosine phosphatase family ABC_trans_N PF14510.1 KPI44563.1 - 0.041 13.9 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal Y_phosphatase PF00102.22 KPI44563.1 - 0.062 12.6 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase TPR_19 PF14559.1 KPI44564.1 - 1.5e-06 28.4 1.4 0.0012 19.0 0.4 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_21 PF09976.4 KPI44564.1 - 0.0008 19.3 1.9 0.011 15.6 0.7 2.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KPI44564.1 - 0.0062 17.0 2.3 17 6.3 0.0 4.5 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KPI44564.1 - 0.042 13.5 0.2 0.15 11.7 0.2 2.0 1 0 0 1 1 1 0 TPR repeat TPR_16 PF13432.1 KPI44564.1 - 1.9 9.2 6.5 0.8 10.4 0.9 3.1 3 1 2 5 5 5 0 Tetratricopeptide repeat DUF2462 PF09495.5 KPI44565.1 - 3.7e-18 66.0 9.2 3.7e-18 66.0 6.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) Lgl_C PF08596.5 KPI44566.1 - 1.9e-114 382.2 0.0 3.7e-114 381.2 0.0 1.5 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 KPI44566.1 - 8.7e-08 31.7 0.3 0.72 9.8 0.0 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 KPI44566.1 - 0.05 11.7 0.0 0.18 9.8 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KPI44566.1 - 0.2 10.3 0.0 11 4.6 0.0 2.8 3 0 0 3 3 3 0 Nup133 N terminal like MRP-L20 PF12824.2 KPI44567.1 - 1.5e-45 155.1 4.5 1.8e-45 154.8 3.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 KPI44567.1 - 0.037 13.8 0.2 0.052 13.3 0.1 1.2 1 0 0 1 1 1 0 Neugrin SMC_N PF02463.14 KPI44569.1 - 1e-65 221.0 12.7 3.8e-35 121.1 6.0 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KPI44569.1 - 8.6e-29 99.9 0.0 3e-28 98.1 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KPI44569.1 - 2.4e-13 50.7 0.4 8.6e-06 25.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain Reo_sigmaC PF04582.7 KPI44569.1 - 6.1e-05 22.3 34.4 0.0029 16.8 2.6 5.3 3 2 2 5 5 5 2 Reovirus sigma C capsid protein AAA_29 PF13555.1 KPI44569.1 - 9.4e-05 21.8 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 KPI44569.1 - 0.0013 17.9 8.9 0.0013 17.9 6.2 7.0 2 2 3 6 6 6 1 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 KPI44569.1 - 0.0025 17.6 8.3 0.0025 17.6 5.8 7.5 2 2 5 8 8 8 2 Tropomyosin like DUF2968 PF11180.3 KPI44569.1 - 0.0055 16.1 5.9 0.0055 16.1 4.1 7.3 4 2 4 8 8 8 1 Protein of unknown function (DUF2968) AAA_13 PF13166.1 KPI44569.1 - 1.7 7.0 97.1 0.15 10.5 4.5 5.8 4 2 2 6 6 6 0 AAA domain AAA_23 PF13476.1 KPI44569.1 - 9.4 6.5 89.9 0.039 14.2 27.0 5.7 2 2 0 2 2 2 0 AAA domain DNA_ligase_A_M PF01068.16 KPI44570.1 - 0.15 11.3 0.0 0.34 10.2 0.0 1.5 2 0 0 2 2 2 0 ATP dependent DNA ligase domain DnaJ PF00226.26 KPI44571.1 - 6.6e-20 70.6 2.4 1.3e-19 69.6 1.7 1.5 1 0 0 1 1 1 1 DnaJ domain Aldo_ket_red PF00248.16 KPI44572.1 - 5.5e-56 189.4 0.0 6.7e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3301 PF11743.3 KPI44572.1 - 0.011 15.2 0.0 0.028 13.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) CoA_binding_2 PF13380.1 KPI44572.1 - 0.11 12.6 0.1 55 3.9 0.0 3.0 2 1 0 3 3 3 0 CoA binding domain DUF998 PF06197.8 KPI44573.1 - 3.4 6.9 22.7 0.68 9.2 12.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF3505 PF12013.3 KPI44574.1 - 0.19 11.9 2.9 3.1 8.0 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3505) Cupin_7 PF12973.2 KPI44575.1 - 6.2e-06 25.9 0.1 9e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.6 KPI44575.1 - 0.038 13.4 0.4 0.065 12.7 0.3 1.5 1 0 0 1 1 1 0 Cupin domain DUF1793 PF08760.6 KPI44576.1 - 1.8e-69 233.0 0.2 3.5e-69 232.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bacteriocin_IIc PF10439.4 KPI44577.1 - 2 8.6 19.8 0.17 11.9 7.2 2.5 1 1 1 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF1604 PF07713.8 KPI44578.1 - 1.7e-30 104.6 5.1 4.1e-30 103.4 1.2 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KPI44578.1 - 1.1e-07 31.4 2.3 3.6e-07 29.8 1.4 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KPI44578.1 - 0.0028 17.4 0.3 0.022 14.5 0.2 2.7 1 1 0 1 1 1 1 DExH-box splicing factor binding site adh_short_C2 PF13561.1 KPI44579.1 - 1.3e-16 61.1 0.1 1.7e-16 60.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI44579.1 - 1.7e-10 41.0 0.1 8.2e-10 38.8 0.1 1.9 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 KPI44579.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KPI44579.1 - 0.0095 15.7 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1183 PF06682.7 KPI44580.1 - 2.8e-91 306.4 1.2 3.3e-91 306.2 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Rick_17kDa_Anti PF05433.10 KPI44580.1 - 0.017 14.7 0.9 0.037 13.6 0.6 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain AA_permease_2 PF13520.1 KPI44581.1 - 3e-59 200.6 50.7 3.8e-59 200.3 35.1 1.1 1 0 0 1 1 1 1 Amino acid permease GFO_IDH_MocA PF01408.17 KPI44581.1 - 1.9e-14 54.2 0.1 3.6e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AA_permease PF00324.16 KPI44581.1 - 2.4e-14 52.5 41.5 3.6e-14 51.9 28.7 1.2 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_6 PF12697.2 KPI44583.1 - 1.4e-19 70.9 0.0 1.8e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI44583.1 - 8.1e-07 28.8 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI44583.1 - 0.00014 21.5 0.0 0.00072 19.1 0.0 2.0 2 1 1 3 3 3 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KPI44583.1 - 0.0096 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KPI44583.1 - 0.028 13.7 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AIG1 PF04548.11 KPI44584.1 - 0.021 13.9 0.1 0.37 9.8 0.0 2.8 3 0 0 3 3 3 0 AIG1 family SET PF00856.23 KPI44586.1 - 2.6e-08 34.3 0.0 1.8e-05 25.1 0.0 2.7 1 1 1 2 2 2 2 SET domain HSF_DNA-bind PF00447.12 KPI44587.1 - 2.2e-38 130.5 0.3 2.2e-38 130.5 0.2 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.19 KPI44587.1 - 4.1e-22 78.3 0.2 8.5e-22 77.2 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Atg14 PF10186.4 KPI44587.1 - 0.14 11.0 2.5 0.24 10.3 1.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 KPI44587.1 - 0.22 11.8 1.6 0.5 10.7 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Abhydrolase_6 PF12697.2 KPI44588.1 - 1.3e-21 77.5 0.4 2.6e-21 76.5 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI44588.1 - 3.7e-11 42.9 0.0 6.2e-11 42.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI44588.1 - 1.7e-05 24.4 0.2 7.9e-05 22.3 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KPI44588.1 - 0.0022 17.8 0.0 0.005 16.6 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase BIR PF00653.16 KPI44589.1 - 1.8e-42 143.6 4.1 7.8e-22 77.4 0.1 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain NAD_binding_2 PF03446.10 KPI44590.1 - 4.4e-29 101.4 0.1 1.1e-28 100.1 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KPI44590.1 - 5.6e-19 68.3 0.4 3.4e-16 59.4 0.0 2.8 2 1 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KPI44590.1 - 3.8e-07 30.4 0.8 8.5e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 KPI44590.1 - 0.00093 18.6 2.1 0.14 11.5 0.9 2.8 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.7 KPI44590.1 - 0.0077 15.6 0.0 0.026 13.8 0.0 1.9 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 KPI44590.1 - 0.0095 15.1 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KPI44590.1 - 0.011 15.4 0.1 0.037 13.6 0.0 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 KPI44590.1 - 0.018 13.8 0.0 0.078 11.7 0.0 1.9 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family UDPG_MGDP_dh_C PF03720.10 KPI44590.1 - 0.035 14.2 0.0 0.52 10.4 0.0 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 KPI44590.1 - 0.25 11.0 1.7 1.3 8.6 0.6 2.4 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GST_N_3 PF13417.1 KPI44592.1 - 4.3e-08 33.2 0.1 7.1e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI44592.1 - 3.2e-05 23.8 0.1 5.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KPI44592.1 - 3.7e-05 23.8 0.0 7.2e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KPI44592.1 - 0.0012 18.7 0.1 0.0029 17.4 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KPI44592.1 - 0.0078 16.6 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ATP-synt_J PF04911.7 KPI44593.1 - 3.1e-09 36.1 0.1 4.7e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 ATP synthase j chain GST_N_3 PF13417.1 KPI44594.1 - 5.6e-11 42.5 0.1 1e-10 41.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KPI44594.1 - 2.4e-07 30.6 0.0 5.8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI44594.1 - 3e-07 30.2 0.5 5.7e-07 29.3 0.3 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KPI44594.1 - 0.00011 22.6 0.5 0.00044 20.6 0.3 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KPI44594.1 - 0.003 17.4 0.0 0.0073 16.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DnaJ PF00226.26 KPI44595.1 - 1.9e-21 75.5 1.5 4.5e-21 74.3 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.23 KPI44596.1 - 0.025 13.9 8.5 0.17 11.2 5.9 2.2 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase HR1 PF02185.11 KPI44598.1 - 0.016 14.9 4.9 0.028 14.1 3.4 1.4 1 0 0 1 1 1 0 Hr1 repeat NDT80_PhoG PF05224.7 KPI44598.1 - 0.022 14.7 0.5 0.055 13.4 0.2 1.8 1 1 0 1 1 1 0 NDT80 / PhoG like DNA-binding family Sugarporin_N PF11471.3 KPI44598.1 - 3.6 7.3 9.7 8.4 6.1 6.7 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF2615 PF11027.3 KPI44599.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) GCIP PF13324.1 KPI44600.1 - 0.2 10.8 4.0 0.26 10.4 2.8 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Cwf_Cwc_15 PF04889.7 KPI44600.1 - 1 8.9 11.3 1.5 8.4 7.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.5 KPI44600.1 - 3 8.1 16.5 5.7 7.2 11.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFIIA PF03153.8 KPI44600.1 - 5 6.9 12.0 6.9 6.4 8.3 1.2 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.17 KPI44601.1 - 3.1e-12 45.9 0.0 7.7e-12 44.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI44601.1 - 2.6e-09 36.9 0.0 5.9e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3458 PF11940.3 KPI44602.1 - 0.073 11.9 1.5 0.19 10.5 0.5 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF3458) UBA PF00627.26 KPI44602.1 - 0.12 12.2 0.2 8.2 6.4 0.0 3.4 3 0 0 3 3 3 0 UBA/TS-N domain Glyco_trans_1_2 PF13524.1 KPI44602.1 - 3.4 7.9 7.7 1 9.6 0.1 3.6 4 1 1 5 5 5 0 Glycosyl transferases group 1 Fungal_trans_2 PF11951.3 KPI44603.1 - 4.7e-07 28.7 0.1 8.8e-07 27.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain YihI PF04220.7 KPI44603.1 - 0.23 10.7 4.3 0.35 10.1 3.0 1.2 1 0 0 1 1 1 0 Der GTPase activator (YihI) Peptidase_C12 PF01088.16 KPI44606.1 - 9.7e-46 155.6 0.0 4.9e-44 150.0 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF3020 PF11223.3 KPI44606.1 - 0.095 13.1 3.5 0.32 11.4 2.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3020) MttA_Hcf106 PF02416.11 KPI44606.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 mttA/Hcf106 family TAF8_C PF10406.4 KPI44607.1 - 9.1e-17 60.8 1.3 1.9e-16 59.8 0.9 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term 2-Hacid_dh_C PF02826.14 KPI44608.1 - 1.1e-53 181.0 0.0 1.5e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KPI44608.1 - 2.1e-25 88.7 0.0 2.4e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KPI44608.1 - 5.5e-06 26.3 0.0 9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KPI44608.1 - 0.027 14.8 0.1 0.1 13.0 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KPI44608.1 - 0.058 13.3 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Fungal_trans_2 PF11951.3 KPI44609.1 - 0.00051 18.7 2.6 0.00051 18.7 1.8 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KPI44610.1 - 1.3e-35 122.7 29.0 1.3e-35 122.7 20.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI44610.1 - 4.1e-09 35.5 16.3 8.9e-08 31.1 11.2 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 KPI44610.1 - 2.5 6.1 10.5 3.7 5.5 7.3 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector Asp PF00026.18 KPI44611.1 - 5.2e-08 32.4 0.3 2.9e-07 30.0 0.2 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Maf PF02545.9 KPI44612.1 - 3.4e-51 173.1 0.0 4.4e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein ILVD_EDD PF00920.16 KPI44614.1 - 3.1e-196 652.8 0.4 3.6e-196 652.6 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family ExoD PF06055.7 KPI44614.1 - 0.043 12.9 0.1 0.082 12.0 0.0 1.4 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD p450 PF00067.17 KPI44615.1 - 3.1e-53 180.9 0.0 1.9e-41 142.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Glycos_transf_2 PF00535.21 KPI44616.1 - 1.2e-29 103.2 0.0 1.4e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KPI44616.1 - 5.5e-17 62.3 0.0 7.2e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KPI44616.1 - 1.7e-06 27.3 0.1 2.9e-06 26.5 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_7N PF13733.1 KPI44616.1 - 0.00047 19.5 0.0 0.00097 18.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_21 PF13506.1 KPI44616.1 - 0.0033 16.7 0.0 0.0056 15.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 NAD_binding_1 PF00175.16 KPI44617.1 - 1e-31 109.7 0.0 2e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KPI44617.1 - 3.3e-22 78.4 0.0 7e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KPI44617.1 - 6.8e-09 35.8 0.0 0.0018 18.1 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KPI44617.1 - 0.00017 21.5 0.0 0.00042 20.2 0.0 1.7 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain zf-C2H2 PF00096.21 KPI44618.1 - 0.0014 18.8 0.4 0.0034 17.6 0.3 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI44618.1 - 0.076 13.3 0.2 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger GFA PF04828.9 KPI44619.1 - 4.6e-10 39.3 0.1 6e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NTP_transf_2 PF01909.18 KPI44620.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain FUSC PF04632.7 KPI44620.1 - 1.7 6.9 9.3 0.24 9.7 0.2 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF2373 PF10180.4 KPI44621.1 - 2.8e-18 65.2 0.6 4.6e-18 64.5 0.4 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) zf-Tim10_DDP PF02953.10 KPI44622.1 - 9.6e-24 82.4 1.4 1.1e-23 82.2 0.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KPI44622.1 - 0.025 14.0 0.8 0.03 13.7 0.6 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) AA_permease_2 PF13520.1 KPI44623.1 - 1.4e-47 162.2 57.3 1.8e-47 161.8 39.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI44623.1 - 2.4e-26 92.1 47.4 3.2e-26 91.7 32.8 1.1 1 0 0 1 1 1 1 Amino acid permease Herpes_US9 PF06072.6 KPI44623.1 - 0.43 10.4 0.0 0.43 10.4 0.0 3.6 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 DUF1212 PF06738.7 KPI44624.1 - 6.7e-44 149.6 15.0 2.2e-40 138.1 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KPI44624.1 - 2.3e-30 105.1 30.1 9.2e-30 103.2 8.6 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3815) GDE_N PF12439.3 KPI44624.1 - 0.16 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal Zn_clus PF00172.13 KPI44625.1 - 9.9e-10 38.1 8.1 1.5e-09 37.5 5.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OrfB_Zn_ribbon PF07282.6 KPI44625.1 - 0.068 12.8 3.5 0.12 12.0 2.4 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain adh_short PF00106.20 KPI44627.1 - 4.1e-17 62.5 1.1 1.9e-16 60.4 0.8 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI44627.1 - 2.3e-10 40.6 0.0 4.8e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI44627.1 - 0.00058 19.5 0.2 0.0024 17.5 0.1 1.9 2 1 0 2 2 2 1 KR domain NAD_binding_2 PF03446.10 KPI44627.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.16 KPI44627.1 - 0.072 12.5 0.1 0.16 11.4 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GST_N_3 PF13417.1 KPI44628.1 - 2.2e-11 43.8 0.0 3.7e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KPI44628.1 - 4.1e-11 42.8 0.0 1.1e-10 41.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI44628.1 - 4.7e-10 39.3 0.1 1.6e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KPI44628.1 - 1.3e-07 31.5 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KPI44628.1 - 0.0091 16.4 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI44628.1 - 0.046 13.6 0.1 0.077 12.8 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tubulin PF00091.20 KPI44629.1 - 1.3e-69 234.3 0.0 1.8e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KPI44629.1 - 2.9e-26 91.9 0.8 7.1e-20 71.3 0.2 2.4 1 1 1 2 2 2 2 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KPI44629.1 - 1.4e-05 25.1 0.0 3.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KPI44629.1 - 0.0035 16.8 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Coa1 PF08695.5 KPI44630.1 - 4.5e-38 129.3 0.0 6.1e-38 128.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 EamA PF00892.15 KPI44630.1 - 0.062 13.3 0.1 0.098 12.6 0.1 1.2 1 0 0 1 1 1 0 EamA-like transporter family CRAL_TRIO PF00650.15 KPI44631.1 - 1.5e-38 131.8 0.0 2.5e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KPI44631.1 - 5.9e-09 35.9 1.7 8.1e-09 35.4 0.1 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KPI44631.1 - 6.5e-05 22.8 0.0 0.00031 20.6 0.0 2.0 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Tropomyosin_1 PF12718.2 KPI44632.1 - 1.3e-05 25.0 13.2 3.1e-05 23.8 9.1 1.6 1 0 0 1 1 1 1 Tropomyosin like TSC22 PF01166.13 KPI44632.1 - 0.0073 16.2 4.0 0.11 12.5 0.0 3.3 3 0 0 3 3 3 1 TSC-22/dip/bun family GAS PF13851.1 KPI44632.1 - 0.014 14.5 11.4 0.029 13.5 6.9 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HALZ PF02183.13 KPI44632.1 - 0.02 14.5 3.7 0.068 12.8 0.0 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper V_ATPase_I PF01496.14 KPI44632.1 - 0.22 9.3 11.7 0.57 7.9 1.5 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 KPI44632.1 - 0.31 10.9 10.6 3.4 7.5 0.6 3.7 3 0 0 3 3 3 0 Basic region leucine zipper IncA PF04156.9 KPI44632.1 - 1.1 8.8 9.3 2.1 7.9 6.5 1.5 1 0 0 1 1 1 0 IncA protein Med9 PF07544.8 KPI44632.1 - 1.2 8.9 9.5 2.3 8.0 0.3 3.3 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF972 PF06156.8 KPI44632.1 - 8.3 6.8 10.1 25 5.2 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Kinetocho_Slk19 PF12709.2 KPI44632.1 - 9.9 6.3 10.6 0.96 9.5 1.8 2.8 2 1 1 3 3 3 0 Central kinetochore-associated TauD PF02668.11 KPI44633.1 - 2e-51 175.1 0.8 2.5e-51 174.8 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SPX PF03105.14 KPI44634.1 - 2.9e-12 46.9 1.9 1.9e-06 27.8 0.1 4.4 3 2 1 4 4 4 2 SPX domain VTC PF09359.5 KPI44634.1 - 1.7e-06 27.2 0.3 1.9e-05 23.8 0.2 2.5 1 1 0 1 1 1 1 VTC domain Amidase PF01425.16 KPI44635.1 - 1.1e-89 301.3 0.0 1.3e-89 301.0 0.0 1.0 1 0 0 1 1 1 1 Amidase DivIC PF04977.10 KPI44636.1 - 3.1 7.3 4.9 0.97 8.9 1.1 1.8 2 0 0 2 2 2 0 Septum formation initiator Cupin_2 PF07883.6 KPI44637.1 - 1.1e-10 40.7 0.3 1.9e-10 40.0 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KPI44637.1 - 6e-07 29.2 0.2 9.7e-07 28.5 0.1 1.4 1 1 1 2 2 2 1 Cupin Cupin_1 PF00190.17 KPI44637.1 - 5.6e-05 22.6 0.0 6.9e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KPI44637.1 - 7.9e-05 22.3 0.1 0.00011 21.8 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 KPI44637.1 - 0.00031 20.0 0.1 0.0023 17.2 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.9 KPI44637.1 - 0.053 13.4 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family RRM_6 PF14259.1 KPI44638.1 - 0.00094 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rogdi_lz PF10259.4 KPI44639.1 - 9.2e-67 225.0 0.0 1.1e-66 224.8 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein UAA PF08449.6 KPI44640.1 - 2e-62 210.8 12.9 4.8e-62 209.6 9.0 1.5 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 KPI44640.1 - 1.9e-05 24.3 7.0 1.9e-05 24.3 4.9 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 KPI44640.1 - 7.7e-05 21.9 2.9 0.01 14.9 0.7 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 KPI44640.1 - 0.00025 21.0 10.1 0.00025 21.0 7.0 3.0 2 2 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 KPI44640.1 - 0.00088 19.4 18.0 0.089 12.9 1.2 2.6 2 1 0 2 2 2 2 Multidrug resistance efflux transporter GTP_EFTU PF00009.22 KPI44642.1 - 1.2e-38 132.4 4.1 6.8e-38 129.9 2.8 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 KPI44642.1 - 3e-11 43.2 1.4 8.2e-06 25.8 0.1 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF-2 PF11987.3 KPI44642.1 - 3.8e-11 42.8 1.3 3.8e-11 42.8 0.9 3.1 2 1 1 3 3 3 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 KPI44642.1 - 9.6e-08 31.9 0.1 2.2e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KPI44642.1 - 1.8e-05 24.0 0.0 3.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.18 KPI44642.1 - 0.00029 20.7 4.1 0.13 12.0 0.2 3.2 2 1 1 3 3 3 2 Dynamin family Miro PF08477.8 KPI44642.1 - 0.001 19.5 0.1 0.0025 18.2 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KPI44642.1 - 0.0014 18.1 0.5 0.0045 16.4 0.4 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation IF2_N PF04760.10 KPI44642.1 - 0.0031 17.1 0.0 0.0071 15.9 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region FeoB_N PF02421.13 KPI44642.1 - 0.0039 16.4 1.0 0.013 14.7 0.7 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 KPI44642.1 - 0.021 14.0 0.3 0.11 11.6 0.2 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.17 KPI44642.1 - 0.044 13.1 0.1 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Ras family Amidohydro_4 PF13147.1 KPI44643.1 - 3.4e-07 30.5 0.3 4.3e-07 30.2 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 KPI44643.1 - 7.8e-07 28.9 0.1 1.6e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KPI44643.1 - 4.9e-05 23.1 0.0 7.1e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family HypD PF01924.11 KPI44643.1 - 0.11 11.1 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase formation hypA family Aldedh PF00171.17 KPI44644.1 - 3e-92 309.3 0.0 1e-89 301.0 0.0 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.13 KPI44645.1 - 8.8e-57 191.9 0.0 1.3e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KPI44645.1 - 0.0031 17.7 16.4 0.13 12.6 2.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI44645.1 - 0.014 15.6 17.3 0.091 13.1 2.7 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2962 PF11176.3 KPI44647.1 - 8.3e-42 142.3 0.8 9.4e-42 142.1 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) DUF4147 PF13660.1 KPI44647.1 - 0.11 11.6 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) HTH_32 PF13565.1 KPI44647.1 - 0.59 10.9 3.6 3.9 8.3 0.2 2.3 2 0 0 2 2 2 0 Homeodomain-like domain REV PF00424.13 KPI44648.1 - 0.26 11.2 9.3 0.8 9.6 2.7 2.7 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) PNK3P PF08645.6 KPI44649.1 - 8.9e-51 171.4 0.0 1.3e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KPI44649.1 - 5.6e-28 97.6 0.0 2.8e-27 95.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KPI44649.1 - 0.00021 20.4 0.0 0.00035 19.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin HAD_2 PF13419.1 KPI44649.1 - 0.039 14.1 0.2 4.1 7.5 0.0 2.9 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase AAA_29 PF13555.1 KPI44649.1 - 0.092 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.5 KPI44649.1 - 0.11 11.6 0.0 14 4.8 0.0 2.5 3 0 0 3 3 3 0 Chromatin associated protein KTI12 DUF258 PF03193.11 KPI44649.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KPI44649.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 KPI44649.1 - 0.15 12.2 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Vps35 PF03635.12 KPI44650.1 - 0 1022.4 0.8 0 1022.2 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Abhydrolase_5 PF12695.2 KPI44651.1 - 5.3e-12 45.7 0.2 9.3e-12 44.9 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 KPI44651.1 - 6.1e-08 31.3 0.2 2.2e-06 26.2 0.2 2.3 2 1 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.2 KPI44651.1 - 2.3e-06 26.7 0.2 7.1e-06 25.0 0.2 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 KPI44651.1 - 1.6e-05 24.9 2.6 3.1e-05 23.9 1.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 KPI44651.1 - 0.0011 17.8 0.4 0.002 16.9 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase Peptidase_S15 PF02129.13 KPI44651.1 - 0.044 13.2 0.0 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Urease_alpha PF00449.15 KPI44652.1 - 3.6e-54 182.0 1.6 4.7e-54 181.6 0.3 1.8 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Amidohydro_1 PF01979.15 KPI44652.1 - 8e-54 183.5 0.4 1.4e-53 182.7 0.3 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_beta PF00699.15 KPI44652.1 - 1.8e-41 140.0 0.1 6.2e-41 138.3 0.0 1.9 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 KPI44652.1 - 1.4e-33 114.8 0.1 2.9e-33 113.8 0.1 1.5 1 0 0 1 1 1 1 Urease, gamma subunit HMG_box PF00505.14 KPI44652.1 - 2.8e-10 40.3 2.2 5.3e-10 39.4 1.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box Amidohydro_3 PF07969.6 KPI44652.1 - 3.5e-06 26.4 0.1 0.00031 20.0 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family HMG_box_2 PF09011.5 KPI44652.1 - 7.4e-05 23.0 2.6 0.00014 22.1 1.8 1.5 1 0 0 1 1 1 1 HMG-box domain Amidohydro_5 PF13594.1 KPI44652.1 - 0.00015 21.5 2.0 0.00051 19.7 1.4 2.0 1 0 0 1 1 1 1 Amidohydrolase Gti1_Pac2 PF09729.4 KPI44653.1 - 8.4e-63 211.2 0.0 1.4e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 Gti1/Pac2 family Ank_2 PF12796.2 KPI44654.1 - 1.9e-33 114.6 3.2 7e-12 45.5 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KPI44654.1 - 1e-28 99.1 9.4 6.7e-11 42.4 0.0 6.5 4 3 4 8 8 8 5 Ankyrin repeats (many copies) SPX PF03105.14 KPI44654.1 - 8.5e-26 91.3 11.4 4.2e-13 49.7 2.4 2.8 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 KPI44654.1 - 3.7e-25 86.4 3.6 4.9e-05 22.9 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 KPI44654.1 - 1.7e-23 80.3 5.1 0.00023 21.0 0.0 8.3 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 KPI44654.1 - 1.7e-17 63.0 7.2 1.8e-07 31.1 0.0 5.8 2 1 5 7 7 7 6 Ankyrin repeats (many copies) GDPD PF03009.12 KPI44654.1 - 3.4e-10 39.8 0.0 1e-09 38.3 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DUF4631 PF15450.1 KPI44654.1 - 0.0082 14.4 1.7 0.028 12.7 0.8 2.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4631) DRAT PF07357.6 KPI44654.1 - 0.028 13.6 0.1 0.076 12.1 0.0 1.6 2 0 0 2 2 2 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) DUF805 PF05656.9 KPI44655.1 - 3 7.7 7.3 5.4 6.8 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF805) PAT1 PF09770.4 KPI44656.1 - 0.12 10.6 2.7 0.14 10.3 1.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PBP1_TM PF14812.1 KPI44656.1 - 2.2 8.6 7.3 2.2 8.6 2.9 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PALP PF00291.20 KPI44657.1 - 1.8e-51 175.1 0.1 2.5e-51 174.7 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PEP_mutase PF13714.1 KPI44657.1 - 1.5e-41 142.1 1.3 2.2e-41 141.6 0.3 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KPI44657.1 - 2e-17 62.6 0.0 3.7e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Isocitrate lyase family 3HCDH_N PF02737.13 KPI44657.1 - 0.02 14.5 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.2 KPI44658.1 - 1.2e-20 74.3 3.7 1.6e-20 73.9 2.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI44658.1 - 4.6e-10 39.4 0.0 8.3e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI44658.1 - 2.6e-09 36.9 0.0 4.2e-09 36.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 KPI44658.1 - 0.0091 15.4 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Thioesterase PF00975.15 KPI44658.1 - 0.044 13.9 0.1 0.073 13.2 0.0 1.3 1 1 0 1 1 1 0 Thioesterase domain p450 PF00067.17 KPI44659.1 - 8e-45 153.2 0.0 9.5e-31 106.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Fungal_trans PF04082.13 KPI44660.1 - 1e-27 96.7 0.5 2.4e-27 95.4 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF72 PF01904.13 KPI44662.1 - 0.0044 16.7 0.3 2.9 7.5 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function DUF72 SHMT PF00464.14 KPI44663.1 - 2.1e-207 688.2 0.0 2.4e-207 688.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 KPI44663.1 - 3.9e-06 26.0 0.0 1.2e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KPI44663.1 - 1.8e-05 23.6 0.0 2.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KPI44663.1 - 0.0016 17.6 0.0 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 KPI44663.1 - 0.092 11.1 0.0 0.24 9.7 0.0 1.6 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain CoA_binding PF02629.14 KPI44664.1 - 8.5e-27 93.5 3.3 1.9e-25 89.2 0.3 2.4 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KPI44664.1 - 1.8e-21 76.3 0.2 3e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KPI44664.1 - 2.1e-07 30.6 0.1 3.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KPI44664.1 - 0.0072 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain UPF0016 PF01169.14 KPI44665.1 - 1.1e-42 143.9 22.4 1.3e-21 76.4 5.3 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DEAD PF00270.24 KPI44667.1 - 1.5e-40 138.4 0.0 8.8e-40 135.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI44667.1 - 2.1e-14 53.1 0.0 2.1e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 KPI44667.1 - 0.0097 15.2 0.0 0.15 11.3 0.0 2.0 2 0 0 2 2 2 1 SecA DEAD-like domain DUF1910 PF08928.5 KPI44667.1 - 0.08 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) ResIII PF04851.10 KPI44667.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ion_trans_2 PF07885.11 KPI44668.1 - 4.8e-23 80.6 26.7 5.1e-16 58.1 7.0 2.8 3 0 0 3 3 3 2 Ion channel zf-CCCH PF00642.19 KPI44669.1 - 0.00011 21.8 1.5 0.00011 21.8 1.1 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NIF3 PF01784.13 KPI44670.1 - 4.7e-52 176.9 0.0 6.3e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF605 PF04652.11 KPI44670.1 - 0.15 11.4 6.6 0.2 11.0 4.6 1.1 1 0 0 1 1 1 0 Vta1 like Transp_cyt_pur PF02133.10 KPI44671.1 - 1.6e-18 66.5 32.2 1.5e-14 53.4 21.3 2.5 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin PHD PF00628.24 KPI44672.1 - 4.9e-11 42.1 7.0 4.9e-11 42.1 4.8 2.5 2 0 0 2 2 2 1 PHD-finger Pkinase PF00069.20 KPI44673.1 - 2.6e-25 89.0 0.0 1.1e-24 86.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI44673.1 - 3.1e-07 29.7 0.9 0.00065 18.8 0.1 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase adh_short_C2 PF13561.1 KPI44674.1 - 6.4e-20 71.9 0.1 7.3e-20 71.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI44674.1 - 0.00029 20.7 0.2 0.00042 20.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Osmo_MPGsynth PF09488.5 KPI44675.1 - 0.02 13.5 0.0 0.026 13.2 0.0 1.1 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) DUF3425 PF11905.3 KPI44677.1 - 2e-22 79.5 4.0 3.6e-22 78.7 1.4 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KPI44677.1 - 0.014 15.3 9.4 0.014 15.3 6.5 2.5 2 1 0 2 2 2 0 bZIP transcription factor DUF3669 PF12417.3 KPI44678.1 - 1.6e-16 59.7 0.2 5.5e-16 58.0 0.2 2.0 1 0 0 1 1 1 1 Zinc finger protein Aspzincin_M35 PF14521.1 KPI44679.1 - 0.056 13.9 0.0 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase AA_permease_2 PF13520.1 KPI44680.1 - 5.7e-40 137.1 52.1 3.2e-31 108.3 20.4 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 KPI44680.1 - 2.3e-19 69.0 46.3 4.7e-17 61.4 19.0 2.0 1 1 1 2 2 2 2 Amino acid permease Pkinase PF00069.20 KPI44681.1 - 2.1e-60 204.0 0.0 2.6e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI44681.1 - 1e-35 123.1 0.0 1.3e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI44681.1 - 1.2e-09 37.5 0.0 1.9e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Fungal_trans PF04082.13 KPI44682.1 - 1.3e-15 56.9 0.0 2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF647 PF04884.9 KPI44684.1 - 2.1e-33 115.6 1.2 2.7e-33 115.2 0.8 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Pkinase PF00069.20 KPI44686.1 - 1.5e-43 148.8 0.0 1.5e-40 139.0 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI44686.1 - 2e-15 56.5 0.0 8.8e-12 44.6 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KPI44686.1 - 0.0045 16.7 1.0 0.042 13.5 0.3 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KPI44686.1 - 0.015 14.3 0.1 0.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Ribosomal_S2 PF00318.15 KPI44687.1 - 1.3e-50 171.5 0.0 2.6e-50 170.5 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S2 Glyco_hydro_72 PF03198.9 KPI44688.1 - 4.1e-135 449.7 8.1 5.1e-135 449.4 5.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KPI44688.1 - 8.1e-14 51.8 0.8 2.5e-13 50.2 0.6 1.9 1 0 0 1 1 1 1 X8 domain DUF4189 PF13827.1 KPI44688.1 - 0.056 13.6 2.3 0.15 12.3 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4189) CFC PF09443.5 KPI44688.1 - 0.073 12.7 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) Pyr_redox_2 PF07992.9 KPI44689.1 - 3e-13 50.1 0.1 7.6e-12 45.5 0.1 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI44689.1 - 1.7e-11 44.3 0.1 2.3e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI44689.1 - 1.3e-07 30.8 6.6 0.00028 19.8 0.0 3.7 3 1 0 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 KPI44689.1 - 9.9e-06 24.6 0.3 0.017 14.0 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KPI44689.1 - 0.00017 21.7 1.0 0.84 9.6 0.0 3.2 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI44689.1 - 0.0014 18.4 3.0 5.8 6.6 0.0 4.1 3 1 1 4 4 4 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KPI44689.1 - 0.041 12.4 1.8 1.7 7.1 0.2 2.7 3 0 0 3 3 3 0 Tryptophan halogenase FAD_oxidored PF12831.2 KPI44689.1 - 0.075 12.0 0.0 0.075 12.0 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase p450 PF00067.17 KPI44690.1 - 3.9e-21 75.0 0.0 9.4e-21 73.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 RF-1 PF00472.15 KPI44691.1 - 1.7e-16 60.0 1.2 2.5e-16 59.4 0.9 1.3 1 0 0 1 1 1 1 RF-1 domain Peptidase_C65 PF10275.4 KPI44692.1 - 0.085 12.1 0.1 0.33 10.2 0.0 1.9 1 1 1 2 2 2 0 Peptidase C65 Otubain MFS_1 PF07690.11 KPI44693.1 - 5.3e-17 61.5 23.8 8.1e-17 60.9 16.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cupin_2 PF07883.6 KPI44694.1 - 5.8e-17 60.9 0.2 1.2e-16 59.9 0.2 1.6 1 0 0 1 1 1 1 Cupin domain LRR19-TM PF15176.1 KPI44694.1 - 0.00017 21.1 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain AraC_binding PF02311.14 KPI44694.1 - 0.00019 21.1 0.0 0.00035 20.2 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Rifin_STEVOR PF02009.11 KPI44694.1 - 0.00023 20.9 0.1 0.0004 20.1 0.1 1.4 1 0 0 1 1 1 1 Rifin/stevor family Protocadherin PF08374.6 KPI44694.1 - 0.0026 17.4 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Protocadherin EutQ PF06249.7 KPI44694.1 - 0.0039 16.7 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Herpes_gE PF02480.11 KPI44694.1 - 0.0055 15.0 0.3 0.0077 14.5 0.1 1.4 1 1 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 KPI44694.1 - 0.015 15.0 0.1 0.022 14.4 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Cupin_1 PF00190.17 KPI44694.1 - 0.017 14.5 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Cupin EphA2_TM PF14575.1 KPI44694.1 - 0.032 14.6 0.0 0.058 13.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_M13 PF01431.16 KPI44694.1 - 0.054 12.6 0.1 0.098 11.8 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M13 Shisa PF13908.1 KPI44694.1 - 0.06 13.5 0.2 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator CENP-C_C PF11699.3 KPI44694.1 - 0.065 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Mif2/CENP-C like Cupin_6 PF12852.2 KPI44694.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Cupin DUF912 PF06024.7 KPI44694.1 - 0.086 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3357 PF11837.3 KPI44694.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) SKG6 PF08693.5 KPI44694.1 - 0.14 11.4 2.2 0.32 10.3 1.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain NLBH PF05211.7 KPI44695.1 - 0.02 14.1 0.9 0.029 13.6 0.6 1.2 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) DASH_Spc34 PF08657.5 KPI44696.1 - 3.5e-47 161.2 2.0 7.5e-26 91.3 0.0 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 DASH_Spc19 PF08287.6 KPI44696.1 - 0.0079 15.8 1.3 0.012 15.2 0.9 1.2 1 0 0 1 1 1 1 Spc19 DUF3584 PF12128.3 KPI44696.1 - 0.02 12.2 1.9 0.026 11.8 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DivIC PF04977.10 KPI44696.1 - 0.051 13.0 2.8 0.17 11.4 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator SusD PF07980.6 KPI44696.1 - 0.061 12.8 0.6 0.088 12.3 0.4 1.2 1 0 0 1 1 1 0 SusD family Hom_end_hint PF05203.11 KPI44696.1 - 0.077 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint DUF4140 PF13600.1 KPI44696.1 - 0.091 13.2 2.9 0.48 10.9 0.6 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Sipho_Gp157 PF05565.6 KPI44696.1 - 0.097 12.2 1.6 0.17 11.4 0.9 1.5 1 1 0 1 1 1 0 Siphovirus Gp157 BLOC1_2 PF10046.4 KPI44696.1 - 0.63 10.2 3.0 8.8 6.5 0.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COesterase PF00135.23 KPI44697.1 - 1.2e-55 189.2 0.0 1.7e-55 188.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI44697.1 - 1.4e-07 31.3 0.3 9.7e-07 28.5 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold SHOCT PF09851.4 KPI44697.1 - 0.021 14.3 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Short C-terminal domain Abhydrolase_2 PF02230.11 KPI44697.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase CENP-O PF09496.5 KPI44699.1 - 1.7e-19 69.8 0.0 6.8e-19 67.9 0.0 2.0 2 1 0 2 2 2 1 Cenp-O kinetochore centromere component DUF869 PF05911.6 KPI44699.1 - 0.0062 14.8 0.5 0.009 14.3 0.3 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) IncA PF04156.9 KPI44699.1 - 0.89 9.1 7.3 0.14 11.7 2.2 1.6 2 0 0 2 2 2 0 IncA protein DivIC PF04977.10 KPI44699.1 - 1.6 8.2 5.5 0.6 9.6 1.4 2.2 2 1 0 2 2 2 0 Septum formation initiator DUF3328 PF11807.3 KPI44700.1 - 1.8e-54 184.7 0.0 2.2e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) UNC-50 PF05216.8 KPI44702.1 - 1.6e-74 249.9 10.4 2.2e-74 249.5 7.2 1.1 1 0 0 1 1 1 1 UNC-50 family DUF2207 PF09972.4 KPI44702.1 - 0.042 12.4 0.1 0.042 12.4 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2721 PF11026.3 KPI44703.1 - 0.091 12.4 4.5 0.17 11.5 0.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Bax1-I PF01027.15 KPI44703.1 - 0.093 12.3 4.5 0.15 11.6 3.1 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF3959 PF13105.1 KPI44703.1 - 0.12 11.6 0.4 0.21 10.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF3936 PF13072.1 KPI44703.1 - 0.13 11.7 0.7 0.3 10.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3936) AMP-binding PF00501.23 KPI44704.1 - 1.6e-58 198.0 0.0 2.2e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI44704.1 - 0.0053 17.6 0.0 0.012 16.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mo25 PF08569.6 KPI44705.1 - 6.2e-86 288.4 1.1 7e-86 288.2 0.8 1.0 1 0 0 1 1 1 1 Mo25-like GOLD_2 PF13897.1 KPI44705.1 - 0.13 12.4 0.5 4.9 7.3 0.1 2.2 1 1 1 2 2 2 0 Golgi-dynamics membrane-trafficking ICL PF00463.16 KPI44706.1 - 1e-266 885.2 0.8 1.5e-266 884.7 0.5 1.2 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KPI44706.1 - 8.7e-12 44.7 0.1 7.6e-11 41.6 0.0 2.1 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Ribosomal_S10 PF00338.17 KPI44707.1 - 2.6e-28 97.6 0.6 3.2e-28 97.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF3328 PF11807.3 KPI44709.1 - 6e-20 71.8 0.0 1.1e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_43 PF04616.9 KPI44709.1 - 2.7e-19 69.3 1.2 3.1e-14 52.7 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Saccharop_dh PF03435.13 KPI44710.1 - 5e-12 45.4 0.0 9.4e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Mis14 PF08641.7 KPI44711.1 - 1.3e-09 38.2 1.2 8.9e-09 35.5 0.8 2.3 1 1 0 1 1 1 1 Kinetochore protein Mis14 like Apolipoprotein PF01442.13 KPI44711.1 - 0.69 9.3 7.7 0.29 10.6 2.0 2.5 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Thiolase_N PF00108.18 KPI44712.1 - 1.7e-64 217.3 0.8 3.8e-64 216.2 0.6 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KPI44712.1 - 1.7e-45 153.3 0.5 4.2e-45 152.1 0.0 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 KPI44712.1 - 0.00037 20.4 0.0 0.0014 18.6 0.0 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 KPI44712.1 - 0.039 13.4 1.7 0.13 11.6 0.9 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Glyco_hydro_92 PF07971.7 KPI44713.1 - 1e-159 532.4 3.2 1.3e-159 532.0 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 CDC45 PF02724.9 KPI44714.1 - 2.7 5.9 5.3 3.7 5.4 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nsp1_C PF05064.8 KPI44716.1 - 4.2e-34 116.6 1.6 4.2e-34 116.6 1.1 1.9 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 KPI44716.1 - 2.7e-06 27.5 210.3 0.00022 21.4 40.1 6.4 1 1 2 3 3 3 2 Nucleoporin FG repeat region ParB PF08775.5 KPI44716.1 - 0.037 14.3 1.2 0.037 14.3 0.8 1.8 2 0 0 2 2 2 0 ParB family ATG16 PF08614.6 KPI44716.1 - 0.27 11.0 7.0 0.19 11.5 1.1 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.7 KPI44716.1 - 0.42 10.4 3.7 0.98 9.2 0.6 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 KPI44716.1 - 0.76 9.6 7.8 1.3 8.8 5.4 1.4 1 0 0 1 1 1 0 Tropomyosin like NPV_P10 PF05531.7 KPI44716.1 - 1.3 9.3 3.9 34 4.7 0.1 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 KPI44716.1 - 1.5 8.9 6.5 11 6.1 1.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 KPI44716.1 - 1.9 7.4 12.2 0.51 9.3 3.3 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 AAA_13 PF13166.1 KPI44716.1 - 3.1 6.1 8.7 0.87 7.9 0.5 2.0 1 1 1 2 2 2 0 AAA domain AAA PF00004.24 KPI44719.1 - 2.6e-16 60.0 0.0 5.3e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KPI44719.1 - 9e-06 25.7 0.0 3.1e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KPI44719.1 - 1.3e-05 26.0 0.0 4.7e-05 24.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KPI44719.1 - 2.2e-05 24.5 0.7 0.0004 20.5 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 KPI44719.1 - 0.0024 17.7 0.0 0.026 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KPI44719.1 - 0.0036 17.0 0.0 0.0082 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KPI44719.1 - 0.0062 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KPI44719.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 KPI44719.1 - 0.026 14.2 0.5 0.07 12.8 0.3 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KPI44719.1 - 0.034 14.4 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.1 KPI44719.1 - 0.037 13.6 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KPI44719.1 - 0.1 11.6 0.1 0.23 10.4 0.0 1.5 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KPI44719.1 - 0.16 12.1 0.0 0.51 10.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Aminotran_1_2 PF00155.16 KPI44720.1 - 1.4e-60 205.1 0.0 1.7e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KPI44720.1 - 0.036 12.3 0.1 0.084 11.1 0.0 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme NAD_binding_10 PF13460.1 KPI44722.1 - 4.1e-10 39.9 0.0 7.4e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KPI44722.1 - 4.4e-05 22.8 0.0 8.1e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KPI44722.1 - 0.006 16.0 0.0 0.83 9.0 0.0 2.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KPI44722.1 - 0.015 14.9 0.1 0.13 11.9 0.0 2.1 1 1 1 2 2 2 0 KR domain adh_short PF00106.20 KPI44722.1 - 0.056 13.3 0.1 0.37 10.6 0.0 2.1 1 1 1 2 2 2 0 short chain dehydrogenase DUF3632 PF12311.3 KPI44723.1 - 5.8e-16 58.8 0.0 3.4e-14 53.0 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) MitMem_reg PF13012.1 KPI44723.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function PH PF00169.24 KPI44724.1 - 4.2e-08 33.3 0.2 1e-07 32.1 0.1 1.7 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 KPI44724.1 - 0.001 18.5 0.0 0.0024 17.3 0.0 1.6 1 0 0 1 1 1 1 GRAM domain PH_11 PF15413.1 KPI44724.1 - 0.12 12.5 1.3 0.84 9.9 0.9 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain DUF692 PF05114.8 KPI44724.1 - 0.17 10.7 0.0 0.41 9.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF692) SAC3_GANP PF03399.11 KPI44725.1 - 0.0011 18.6 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family MIP PF00230.15 KPI44727.1 - 1.2e-42 145.9 11.2 7.2e-24 84.5 1.0 2.1 1 1 1 2 2 2 2 Major intrinsic protein DUF4201 PF13870.1 KPI44728.1 - 0.058 12.8 2.9 0.071 12.5 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Histone_HNS PF00816.16 KPI44728.1 - 0.56 10.7 3.5 0.65 10.5 1.0 2.0 1 1 1 2 2 2 0 H-NS histone family Lge1 PF11488.3 KPI44728.1 - 0.81 9.9 3.0 1.1 9.4 0.7 2.0 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Osmo_CC PF08946.5 KPI44728.1 - 0.99 9.4 5.5 0.89 9.6 2.2 2.2 2 1 0 2 2 2 0 Osmosensory transporter coiled coil FlxA PF14282.1 KPI44728.1 - 1.6 8.6 9.7 2.8 7.9 6.7 1.4 1 0 0 1 1 1 0 FlxA-like protein ACTH_domain PF00976.13 KPI44730.1 - 1.2 9.0 4.8 2.8 7.8 3.3 1.6 1 0 0 1 1 1 0 Corticotropin ACTH domain ABM PF03992.11 KPI44731.1 - 6.4e-06 26.1 0.4 9.4e-06 25.5 0.3 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF718 PF05336.8 KPI44731.1 - 0.078 12.7 0.2 0.12 12.2 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF718) PUA PF01472.15 KPI44732.1 - 7.8e-16 57.5 0.1 1.6e-15 56.5 0.1 1.5 1 1 0 1 1 1 1 PUA domain Myosin_N PF02736.14 KPI44732.1 - 0.089 12.4 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain DUF4443 PF14544.1 KPI44732.1 - 0.15 11.9 0.0 0.52 10.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4443) F-box-like PF12937.2 KPI44733.1 - 7.6e-13 47.9 0.1 1.6e-12 46.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KPI44733.1 - 3.7e-12 44.9 9.1 1.2 9.4 0.0 9.0 10 0 0 10 10 10 3 Leucine Rich repeat F-box PF00646.28 KPI44733.1 - 2.9e-07 29.9 0.5 1.1e-06 28.1 0.1 2.2 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 KPI44733.1 - 7.6e-06 25.4 8.9 0.14 11.7 0.0 5.6 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) PRANC PF09372.5 KPI44733.1 - 0.051 13.5 0.2 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 PRANC domain LRR_1 PF00560.28 KPI44733.1 - 0.16 12.0 21.6 3 8.2 0.1 7.7 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_7 PF13504.1 KPI44733.1 - 5.3 7.6 17.7 28 5.5 0.1 7.6 8 0 0 8 8 8 0 Leucine rich repeat CDP-OH_P_transf PF01066.16 KPI44734.1 - 1.9e-15 56.9 7.1 1.9e-15 56.9 4.9 1.7 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase His_Phos_1 PF00300.17 KPI44735.1 - 6.6e-15 55.5 1.0 1.5e-13 51.1 0.1 2.7 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Amidohydro_1 PF01979.15 KPI44737.1 - 2.1e-38 132.8 0.0 2.9e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KPI44737.1 - 0.00067 19.4 0.3 0.0023 17.7 0.2 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KPI44737.1 - 0.0034 16.6 0.4 0.84 8.7 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family MmgE_PrpD PF03972.9 KPI44739.1 - 6.1e-66 222.4 0.1 7.3e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Nuc_sug_transp PF04142.10 KPI44741.1 - 6.5e-09 35.2 1.4 9.6e-09 34.6 1.0 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KPI44741.1 - 1.9e-06 27.0 7.8 3.1e-06 26.3 5.4 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KPI44741.1 - 9.9e-06 25.6 28.7 0.0024 17.8 4.1 3.4 3 1 1 4 4 4 2 EamA-like transporter family TPT PF03151.11 KPI44741.1 - 0.00052 19.6 18.2 0.00074 19.1 4.4 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family O-antigen_lig PF13425.1 KPI44741.1 - 0.002 18.0 2.4 0.002 18.0 1.7 3.4 3 1 1 4 4 4 1 O-antigen ligase like membrane protein Med18 PF09637.5 KPI44742.1 - 7.1e-26 91.2 0.0 8.4e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Med18 protein MARVEL PF01284.18 KPI44744.1 - 0.0016 18.2 26.7 0.0044 16.8 17.4 2.0 1 1 1 2 2 2 1 Membrane-associating domain DUF417 PF04224.7 KPI44744.1 - 0.012 14.9 0.8 2.4 7.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF417 DUF4006 PF13179.1 KPI44744.1 - 1.7 8.2 3.9 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF4006) DUF4175 PF13779.1 KPI44744.1 - 1.8 6.1 5.0 2.5 5.6 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2839 PF10999.3 KPI44744.1 - 5.4 7.1 6.1 10 6.2 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Sas10_Utp3 PF04000.10 KPI44745.1 - 5.7e-15 55.2 0.5 1.4e-14 54.0 0.2 1.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family HET PF06985.6 KPI44746.1 - 1.6e-21 76.9 6.2 5.1e-18 65.5 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) zf-MYND PF01753.13 KPI44747.1 - 6.8e-10 38.6 3.0 6.8e-10 38.6 2.1 3.1 3 1 0 3 3 3 2 MYND finger Glutaredoxin PF00462.19 KPI44748.1 - 4.2e-20 71.4 0.0 6.5e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF4124 PF13511.1 KPI44748.1 - 0.0024 17.8 0.0 0.0027 17.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4124) DUF836 PF05768.9 KPI44748.1 - 0.003 17.8 0.0 0.0036 17.5 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_2 PF13409.1 KPI44748.1 - 0.0075 16.2 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.1 KPI44748.1 - 0.0078 16.4 0.2 0.033 14.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.1 KPI44748.1 - 0.0081 16.3 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.1 KPI44748.1 - 0.031 13.8 0.0 0.061 12.8 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin TraF PF13728.1 KPI44748.1 - 0.04 13.3 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin PF00085.15 KPI44748.1 - 0.044 13.4 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.15 KPI44748.1 - 0.16 11.4 0.3 0.57 9.6 0.2 1.8 1 1 1 2 2 2 0 DSBA-like thioredoxin domain IBR PF01485.16 KPI44750.1 - 0.91 9.4 3.8 2.4 8.0 2.6 1.7 1 1 0 1 1 1 0 IBR domain MBOAT PF03062.14 KPI44751.1 - 1.4e-43 149.2 0.4 1.4e-43 149.2 0.3 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Polyketide_cyc PF03364.15 KPI44752.1 - 0.0034 17.3 0.0 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 KPI44752.1 - 0.055 13.6 4.4 0.031 14.4 1.0 2.1 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport SdpI PF13630.1 KPI44752.1 - 0.075 12.7 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family DnaJ PF00226.26 KPI44753.1 - 1.6e-25 88.6 0.3 1.6e-25 88.6 0.2 2.1 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 KPI44753.1 - 2.2e-10 40.3 4.7 2.5e-10 40.1 1.6 2.3 1 1 1 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KPI44753.1 - 8e-10 38.5 1.2 8e-10 38.5 0.8 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KPI44753.1 - 2.1e-07 30.9 2.7 0.00097 19.2 1.0 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KPI44753.1 - 1e-05 25.5 6.6 0.012 15.9 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI44753.1 - 0.0025 18.0 3.3 0.46 10.9 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KPI44753.1 - 0.049 13.5 5.9 2.9 7.9 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger CpXC PF14353.1 KPI44753.1 - 0.056 13.4 6.7 0.3 11.0 0.4 3.3 3 0 0 3 3 3 0 CpXC protein Zn-ribbon_8 PF09723.5 KPI44753.1 - 3.1 7.8 4.8 8.4 6.4 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain DUF2175 PF09943.4 KPI44753.1 - 3.9 7.5 6.3 2.5 8.1 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) Med10 PF09748.4 KPI44754.1 - 2.2e-31 108.3 0.2 4.9e-31 107.2 0.1 1.6 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.2 KPI44754.1 - 0.045 13.3 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF4267 PF14087.1 KPI44755.1 - 1.6e-09 37.3 0.3 2e-09 37.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Clp1 PF06807.9 KPI44756.1 - 0.00073 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CorA PF01544.13 KPI44757.1 - 0.0016 17.5 0.0 0.0037 16.3 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3708 PF12501.3 KPI44757.1 - 0.15 11.8 1.0 0.41 10.4 0.6 1.8 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter zf-RING_2 PF13639.1 KPI44758.1 - 4.1e-13 48.9 6.4 1.1e-12 47.5 4.5 1.8 1 0 0 1 1 1 1 Ring finger domain Fungal_trans_2 PF11951.3 KPI44758.1 - 5.6e-09 35.0 8.6 1.9e-08 33.3 5.9 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C3HC4_2 PF13923.1 KPI44758.1 - 4.8e-08 32.8 7.0 1.3e-07 31.5 4.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KPI44758.1 - 3.5e-06 27.0 1.3 1.3e-05 25.1 0.9 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KPI44758.1 - 3.5e-06 26.5 6.2 3.5e-06 26.5 4.3 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI44758.1 - 1.5e-05 24.5 4.8 4.4e-05 23.1 3.3 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KPI44758.1 - 0.0003 20.3 3.3 0.00075 19.1 2.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 KPI44758.1 - 0.00097 18.6 5.7 0.0027 17.1 4.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 KPI44758.1 - 0.0018 18.0 4.0 0.0048 16.7 0.8 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1049 PF06305.6 KPI44758.1 - 0.0045 16.4 0.6 0.0092 15.4 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) zf-RING_UBOX PF13445.1 KPI44758.1 - 0.012 15.2 5.8 0.032 13.9 4.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger TMEM154 PF15102.1 KPI44758.1 - 0.051 13.2 0.0 0.17 11.5 0.0 2.0 1 0 0 1 1 1 0 TMEM154 protein family zf-RING_6 PF14835.1 KPI44758.1 - 0.068 12.9 1.6 2 8.2 2.2 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein FANCL_C PF11793.3 KPI44758.1 - 0.1 12.5 1.8 0.27 11.2 1.2 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 KPI44758.1 - 1.1 9.3 4.2 3.6 7.6 2.9 2.0 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 KPI44758.1 - 6.4 6.7 15.2 0.13 12.1 5.5 2.1 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING LLC1 PF14945.1 KPI44759.1 - 0.1 12.8 0.8 0.16 12.3 0.5 1.4 1 1 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Sugar_tr PF00083.19 KPI44760.1 - 2.3e-132 441.8 28.0 2.6e-132 441.6 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI44760.1 - 9.7e-26 90.3 49.2 2.8e-22 78.9 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 KPI44761.1 - 5.1e-47 160.4 0.0 6.7e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Metallophos PF00149.23 KPI44761.1 - 1e-06 28.2 5.3 6.2e-06 25.7 3.7 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KPI44761.1 - 0.014 15.1 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PAT1 PF09770.4 KPI44762.1 - 0.78 7.9 17.0 0.96 7.6 11.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Abhydrolase_6 PF12697.2 KPI44763.1 - 6.9e-11 42.4 2.1 1.1e-10 41.8 1.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI44763.1 - 9.2e-09 35.1 0.0 1.8e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI44763.1 - 0.036 13.2 0.0 0.087 12.0 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.15 KPI44763.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Sugar_tr PF00083.19 KPI44764.1 - 6e-82 275.6 23.0 6.9e-82 275.4 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI44764.1 - 1.4e-19 70.0 30.4 2.1e-19 69.4 16.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Rpn3_C PF08375.6 KPI44765.1 - 7.3e-25 87.1 0.8 2.1e-24 85.6 0.6 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 KPI44765.1 - 9.1e-12 45.2 0.1 6.9e-11 42.4 0.0 2.4 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KPI44765.1 - 0.00029 20.6 0.6 0.0025 17.5 0.4 2.3 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 DUF2888 PF11135.3 KPI44765.1 - 0.013 15.2 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) PCI_Csn8 PF10075.4 KPI44768.1 - 1.1e-40 138.7 0.0 2.4e-40 137.5 0.0 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 AMP-binding PF00501.23 KPI44768.1 - 1.7e-29 102.4 0.0 3.2e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme SAC3_GANP PF03399.11 KPI44768.1 - 2.7e-21 76.0 0.1 1.3e-20 73.8 0.0 2.0 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family GH3 PF03321.8 KPI44768.1 - 0.032 12.7 0.1 0.051 12.0 0.1 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter DUF951 PF06107.6 KPI44768.1 - 0.074 12.5 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) EHN PF06441.7 KPI44769.1 - 1e-28 99.4 0.1 1.8e-28 98.6 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KPI44769.1 - 9.2e-12 45.3 0.9 1.6e-11 44.5 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI44769.1 - 1.3e-05 24.8 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2183 PF09949.4 KPI44770.1 - 2.6e-31 107.5 0.0 6.7e-31 106.2 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) SecE PF00584.15 KPI44771.1 - 1.1e-12 47.2 0.0 1.3e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Glucan_synthase PF02364.10 KPI44772.1 - 0 1490.1 0.0 0 1489.6 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KPI44772.1 - 1.6e-40 137.6 0.7 4.4e-40 136.2 0.5 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.16 KPI44772.1 - 3.5e-35 121.6 0.0 5e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KPI44772.1 - 0.032 12.5 0.0 0.055 11.7 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme tRNA_m1G_MT PF01746.16 KPI44774.1 - 3.4e-29 101.7 0.0 3.6e-22 78.8 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase TRP PF06011.7 KPI44775.1 - 1.1e-123 413.0 34.0 3.4e-90 302.7 14.4 3.0 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KPI44775.1 - 8e-40 136.1 0.2 1.3e-39 135.5 0.1 1.3 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 KPI44775.1 - 9.7e-05 22.6 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 ML domain IATP PF04568.7 KPI44776.1 - 6e-16 58.3 3.2 1.2e-11 44.4 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial ATPase inhibitor, IATP IncA PF04156.9 KPI44776.1 - 0.003 17.1 0.3 0.003 17.1 0.2 1.2 1 0 0 1 1 1 1 IncA protein RNA_pol_3_Rpc31 PF11705.3 KPI44776.1 - 0.059 13.3 0.1 0.06 13.2 0.1 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 HSBP1 PF06825.7 KPI44776.1 - 0.11 12.0 0.7 0.38 10.3 0.5 1.9 1 1 0 1 1 1 0 Heat shock factor binding protein 1 DivIC PF04977.10 KPI44776.1 - 0.12 11.8 0.5 0.2 11.1 0.4 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4315 PF14193.1 KPI44776.1 - 1.7 8.5 4.8 1 9.2 1.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) bZIP_1 PF00170.16 KPI44776.1 - 6 6.8 8.1 17 5.4 1.7 2.4 2 0 0 2 2 2 0 bZIP transcription factor DAO PF01266.19 KPI44777.1 - 2e-34 119.0 0.2 3.3e-34 118.3 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI44777.1 - 0.0012 18.7 0.1 0.0039 17.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KPI44777.1 - 0.0013 17.6 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KPI44777.1 - 0.0035 17.1 0.1 0.012 15.3 0.1 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KPI44777.1 - 0.004 16.1 0.0 0.0062 15.4 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Mqo PF06039.10 KPI44777.1 - 0.054 11.6 0.0 0.19 9.8 0.0 1.8 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.19 KPI44777.1 - 0.064 12.0 0.1 0.12 11.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 KPI44777.1 - 0.098 12.7 0.0 0.35 10.8 0.0 1.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RRM_1 PF00076.17 KPI44778.1 - 1.2e-08 34.4 0.0 2.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI44778.1 - 2.8e-07 30.4 0.0 4.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI44778.1 - 0.043 13.6 0.1 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_transf_20 PF00982.16 KPI44779.1 - 8.4e-128 426.8 0.0 1.3e-118 396.5 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KPI44779.1 - 2.5e-71 239.3 0.1 8.3e-71 237.6 0.0 1.8 2 0 0 2 2 2 1 Trehalose-phosphatase ADSL_C PF10397.4 KPI44779.1 - 0.0073 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus HAD PF12710.2 KPI44779.1 - 0.13 12.4 0.7 14 5.7 0.0 2.8 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Cutinase PF01083.17 KPI44780.1 - 1e-22 80.7 0.4 1e-22 80.7 0.2 1.7 2 0 0 2 2 2 1 Cutinase PE-PPE PF08237.6 KPI44780.1 - 0.0077 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain Sporozoite_P67 PF05642.6 KPI44780.1 - 0.16 9.8 8.6 0.22 9.3 5.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NPR2 PF06218.6 KPI44780.1 - 0.44 9.1 0.0 0.44 9.1 0.0 1.9 2 0 0 2 2 2 0 Nitrogen permease regulator 2 TRI12 PF06609.8 KPI44781.1 - 1.3e-32 112.7 15.1 4e-32 111.2 9.9 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KPI44781.1 - 4.9e-10 38.6 44.1 4.9e-10 38.6 30.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI44781.1 - 2.3e-06 26.4 13.1 2.3e-06 26.4 9.1 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter Trypan_PARP PF05887.6 KPI44782.1 - 0.33 10.7 54.2 0.032 14.0 10.2 3.7 2 1 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) RNA_pol_Rpb1_5 PF04998.12 KPI44783.1 - 1.3e-81 273.8 0.3 2.8e-81 272.8 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KPI44783.1 - 1.5e-67 226.7 0.2 3.8e-67 225.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 KPI44783.1 - 1.6e-65 221.6 0.1 3.3e-65 220.5 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 KPI44783.1 - 3.9e-37 127.4 0.0 8e-37 126.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KPI44783.1 - 1.2e-27 95.8 0.3 3.3e-27 94.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Chorein_N PF12624.2 KPI44783.1 - 0.19 11.2 0.0 0.47 10.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal region of Chorein, a TM vesicle-mediated sorter Mucin PF01456.12 KPI44783.1 - 0.53 10.0 9.6 8.8 6.0 3.7 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein SH3_9 PF14604.1 KPI44784.1 - 8.7e-10 38.0 0.0 1.9e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KPI44784.1 - 4.9e-09 36.3 0.0 1.5e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 KPI44784.1 - 2.4e-08 33.2 0.0 5.3e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.12 KPI44784.1 - 2.9e-08 33.4 0.1 4.6e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 KPI44784.1 - 8e-07 29.3 0.0 2e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 KPI44784.1 - 0.0013 18.1 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 KPI44784.1 - 0.023 14.8 0.1 0.039 14.1 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF2155 PF09923.4 KPI44784.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2155) PH_8 PF15409.1 KPI44784.1 - 0.05 13.6 0.0 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DUF1195 PF06708.6 KPI44787.1 - 0.59 9.5 3.9 1 8.7 2.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1195) Cuticle_1 PF08140.6 KPI44789.1 - 0.03 14.1 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Crustacean cuticle protein repeat TPR_11 PF13414.1 KPI44790.1 - 3.8e-37 125.7 31.6 1.9e-08 33.8 0.0 12.1 11 1 2 13 13 13 7 TPR repeat TPR_14 PF13428.1 KPI44790.1 - 3.5e-25 86.1 41.0 0.0046 17.4 0.2 16.4 12 4 6 18 18 18 7 Tetratricopeptide repeat TPR_2 PF07719.12 KPI44790.1 - 1.1e-24 84.2 28.0 0.022 14.6 0.0 14.7 18 0 0 18 18 16 6 Tetratricopeptide repeat TPR_19 PF14559.1 KPI44790.1 - 2.3e-22 79.1 41.1 6.2e-08 32.8 1.2 10.5 8 4 3 11 11 10 7 Tetratricopeptide repeat TPR_17 PF13431.1 KPI44790.1 - 2.7e-22 77.0 21.5 0.0034 17.4 0.1 13.7 16 0 0 16 16 14 5 Tetratricopeptide repeat TPR_1 PF00515.23 KPI44790.1 - 3.6e-21 73.8 16.1 0.011 15.2 0.0 12.0 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_12 PF13424.1 KPI44790.1 - 6.8e-21 74.0 33.0 1.4e-05 24.8 0.1 11.2 11 4 4 15 15 14 8 Tetratricopeptide repeat TPR_16 PF13432.1 KPI44790.1 - 1.8e-20 73.0 50.0 3.9e-07 30.5 0.8 12.4 12 3 1 13 13 11 5 Tetratricopeptide repeat TPR_8 PF13181.1 KPI44790.1 - 2.5e-16 58.1 9.5 0.34 10.7 0.0 12.4 14 1 1 15 15 14 4 Tetratricopeptide repeat TPR_9 PF13371.1 KPI44790.1 - 1.9e-10 40.4 13.6 0.12 12.1 0.1 8.5 6 3 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 KPI44790.1 - 2.8e-09 36.0 21.4 0.1 12.4 0.0 10.6 10 1 0 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 KPI44790.1 - 6.4e-08 32.5 20.3 2.1 8.9 0.0 11.9 13 0 0 13 13 11 1 Tetratricopeptide repeat TPR_20 PF14561.1 KPI44790.1 - 0.0054 16.8 29.4 0.1 12.7 0.3 7.6 7 2 1 8 8 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 KPI44790.1 - 0.029 14.7 24.9 3.9 8.1 0.0 10.4 12 0 0 12 12 10 0 Tetratricopeptide repeat TPR_10 PF13374.1 KPI44790.1 - 5.3 7.1 20.6 40 4.3 0.2 7.6 9 0 0 9 9 8 0 Tetratricopeptide repeat zf-RING_2 PF13639.1 KPI44791.1 - 6.1e-05 22.7 6.3 0.00012 21.8 4.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KPI44791.1 - 0.0007 19.2 6.2 0.0012 18.5 4.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KPI44791.1 - 0.013 15.1 0.3 0.034 13.8 0.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.20 KPI44791.1 - 0.033 13.8 7.1 0.059 13.0 4.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI44791.1 - 0.039 13.9 6.6 0.069 13.1 4.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2413 PF10310.4 KPI44793.1 - 4.9e-125 417.8 0.3 2.8e-121 405.4 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 KPI44793.1 - 0.38 10.8 1.9 2.1 8.4 0.0 2.6 2 1 1 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain COesterase PF00135.23 KPI44794.1 - 3.9e-88 296.4 0.0 1.3e-70 238.6 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI44794.1 - 0.00075 19.1 0.3 0.0015 18.1 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold UQ_con PF00179.21 KPI44795.1 - 1.4e-41 141.2 0.0 1.6e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KPI44795.1 - 6.9e-08 32.3 0.0 8.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KPI44795.1 - 0.012 15.4 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 0 RWD domain TerB PF05099.8 KPI44796.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TerB PRANC PF09372.5 KPI44796.1 - 0.078 12.9 0.2 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 PRANC domain Lamp PF01299.12 KPI44797.1 - 0.22 10.6 2.4 0.44 9.6 1.6 1.5 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) THOC7 PF05615.8 KPI44798.1 - 6.6e-13 49.1 4.6 6.9e-13 49.0 2.3 1.8 1 1 1 2 2 2 1 Tho complex subunit 7 TPR_MLP1_2 PF07926.7 KPI44798.1 - 0.056 13.1 0.4 0.19 11.4 0.3 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3560 PF12083.3 KPI44799.1 - 0.027 14.5 1.2 0.043 13.8 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) AFG1_ATPase PF03969.11 KPI44799.1 - 0.034 12.9 0.1 0.047 12.4 0.1 1.1 1 0 0 1 1 1 0 AFG1-like ATPase MtrF PF09472.5 KPI44799.1 - 0.054 12.7 1.2 0.099 11.8 0.8 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) GTP_EFTU PF00009.22 KPI44801.1 - 7.6e-44 149.3 0.0 1.3e-43 148.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KPI44801.1 - 1.7e-27 95.3 0.0 6.2e-27 93.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KPI44801.1 - 2.4e-17 62.5 0.0 6.9e-17 61.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KPI44801.1 - 5.4e-06 26.1 0.0 1.6e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KPI44801.1 - 1.1e-05 25.4 0.0 4.1e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KPI44801.1 - 4.8e-05 23.2 0.1 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KPI44801.1 - 8.9e-05 22.9 0.1 0.00028 21.3 0.1 1.9 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 KPI44801.1 - 0.021 14.1 0.0 0.049 13.0 0.0 1.6 1 0 0 1 1 1 0 Ras family Septin PF00735.13 KPI44801.1 - 0.15 11.0 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Septin Acyltransferase PF01553.16 KPI44802.1 - 1.4e-15 56.8 0.0 2.3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ThiF PF00899.16 KPI44803.1 - 2.3e-38 131.1 0.5 1e-37 128.9 0.1 1.9 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 KPI44803.1 - 1.5e-27 95.1 0.1 2.7e-27 94.3 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 KPI44803.1 - 1.3e-23 82.3 0.7 2.3e-23 81.5 0.5 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KPI44803.1 - 6.5e-13 47.8 2.6 6.5e-13 47.8 1.8 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 KPI44803.1 - 5e-05 23.4 0.0 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 KPI44803.1 - 0.0024 17.4 0.0 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain DAO PF01266.19 KPI44803.1 - 0.031 13.1 0.0 0.069 12.0 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase UPF0052 PF01933.13 KPI44803.1 - 0.039 13.2 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 TrkA_N PF02254.13 KPI44803.1 - 0.047 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 KPI44803.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KPI44803.1 - 0.14 12.3 0.2 0.47 10.7 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Ecm33 PF12454.3 KPI44803.1 - 0.46 10.4 4.3 0.97 9.3 3.0 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein DUF4336 PF14234.1 KPI44805.1 - 3.6e-10 39.4 0.1 8.5e-06 25.1 0.0 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Elongin_A PF06881.6 KPI44806.1 - 2.5e-11 43.9 2.7 5.1e-05 23.6 0.0 2.5 1 1 1 2 2 2 2 RNA polymerase II transcription factor SIII (Elongin) subunit A MFS_1 PF07690.11 KPI44807.1 - 9.5e-20 70.6 30.2 9.8e-16 57.4 23.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ATP-synt_E PF05680.7 KPI44807.1 - 0.00098 19.0 0.6 0.0034 17.3 0.4 1.9 1 0 0 1 1 1 1 ATP synthase E chain RRF PF01765.14 KPI44808.1 - 7.1e-28 97.1 0.2 2.4e-27 95.4 0.1 1.8 1 1 0 1 1 1 1 Ribosome recycling factor DUF3512 PF12024.3 KPI44808.1 - 0.12 11.6 1.4 0.37 10.0 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3512) GSK-3_bind PF05350.7 KPI44808.1 - 0.56 9.6 5.9 0.069 12.5 0.8 1.8 2 0 0 2 2 2 0 Glycogen synthase kinase-3 binding 7tm_2 PF00002.19 KPI44809.1 - 1.6e-06 27.3 8.3 2.5e-06 26.7 5.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 KPI44809.1 - 0.00051 19.0 3.6 0.0012 17.7 2.5 1.6 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor AD PF09793.4 KPI44809.1 - 0.013 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain Cyclin PF08613.6 KPI44810.1 - 6.3e-31 107.8 0.0 8.7e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin AlaDh_PNT_N PF05222.10 KPI44810.1 - 0.03 14.3 0.0 10 6.1 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain Cyclin_N PF00134.18 KPI44810.1 - 0.056 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Ribosomal_L31 PF01197.13 KPI44811.1 - 0.0014 18.6 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L31 p450 PF00067.17 KPI44812.1 - 1.3e-49 169.0 0.0 1.6e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3390 PF11870.3 KPI44812.1 - 0.068 13.1 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) F-box-like PF12937.2 KPI44813.1 - 0.064 12.9 0.1 0.25 11.1 0.1 2.0 2 1 0 2 2 2 0 F-box-like Glyco_hydro_43 PF04616.9 KPI44814.1 - 1.8e-63 214.3 1.7 4.9e-33 114.4 0.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 DUF377 PF04041.8 KPI44814.1 - 0.053 12.2 0.0 1.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF377) GPI-anchored PF10342.4 KPI44815.1 - 8.4e-14 51.8 1.6 8.4e-14 51.8 1.1 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PixA PF12306.3 KPI44815.1 - 0.078 12.8 1.8 0.096 12.5 0.0 1.9 2 0 0 2 2 2 0 Inclusion body protein Pex14_N PF04695.8 KPI44815.1 - 0.35 10.9 6.0 0.8 9.7 4.2 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3827 PF12877.2 KPI44815.1 - 3.5 5.6 7.9 5 5.0 4.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) Macoilin PF09726.4 KPI44815.1 - 7.9 4.6 13.4 9.8 4.3 9.3 1.1 1 0 0 1 1 1 0 Transmembrane protein UQ_con PF00179.21 KPI44816.1 - 1.2e-26 92.8 0.1 3.7e-21 75.0 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UEV PF05743.8 KPI44816.1 - 0.0019 17.8 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 UEV domain Fungal_trans PF04082.13 KPI44817.1 - 0.00069 18.5 1.5 0.0011 17.9 0.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain GAT PF03127.9 KPI44818.1 - 0.0058 16.5 1.9 0.012 15.5 0.2 2.2 1 1 1 2 2 2 1 GAT domain Dor1 PF04124.7 KPI44818.1 - 0.024 13.1 0.5 0.033 12.6 0.3 1.3 1 0 0 1 1 1 0 Dor1-like family AAA_13 PF13166.1 KPI44818.1 - 0.033 12.6 2.2 0.032 12.6 0.9 1.3 1 1 0 1 1 1 0 AAA domain YgaB PF14182.1 KPI44818.1 - 0.057 13.6 0.6 0.14 12.4 0.4 1.6 1 0 0 1 1 1 0 YgaB-like protein ADIP PF11559.3 KPI44818.1 - 0.076 12.9 4.4 0.14 12.0 2.8 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 KPI44818.1 - 0.21 10.7 3.1 0.3 10.2 2.1 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein HET PF06985.6 KPI44819.1 - 1.3e-27 96.6 0.2 1.3e-27 96.6 0.1 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) ADH_zinc_N PF00107.21 KPI44820.1 - 0.0053 16.3 0.7 0.019 14.5 0.2 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI44820.1 - 0.04 14.8 1.4 0.1 13.4 0.0 2.2 2 1 0 2 2 2 0 Zinc-binding dehydrogenase AAA PF00004.24 KPI44821.1 - 1.4e-50 170.9 0.0 2.3e-42 144.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KPI44821.1 - 9.9e-08 31.5 0.0 5.9e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 KPI44821.1 - 1.7e-07 31.3 0.7 4.8e-06 26.6 0.0 3.3 3 0 0 3 3 2 1 AAA ATPase domain AAA_2 PF07724.9 KPI44821.1 - 7.9e-06 25.8 0.0 2.7e-05 24.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KPI44821.1 - 6.6e-05 23.0 0.1 0.0022 18.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KPI44821.1 - 0.00017 21.3 0.0 0.00071 19.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KPI44821.1 - 0.0005 19.5 0.0 0.0021 17.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KPI44821.1 - 0.00065 19.5 0.0 0.0041 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KPI44821.1 - 0.0018 18.4 0.0 0.0088 16.2 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 KPI44821.1 - 0.0023 18.2 0.0 0.051 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KPI44821.1 - 0.0031 17.2 0.0 0.022 14.4 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 KPI44821.1 - 0.0036 17.1 0.1 0.025 14.4 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 KPI44821.1 - 0.0043 17.8 0.0 0.028 15.2 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.1 KPI44821.1 - 0.0067 16.0 0.1 0.042 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Bromodomain PF00439.20 KPI44821.1 - 0.0067 16.3 0.0 0.02 14.7 0.0 1.8 1 0 0 1 1 1 1 Bromodomain TIP49 PF06068.8 KPI44821.1 - 0.0088 14.8 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Sigma54_activat PF00158.21 KPI44821.1 - 0.0088 15.5 0.0 1.4 8.3 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KPI44821.1 - 0.0096 15.9 0.0 0.088 12.8 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.22 KPI44821.1 - 0.01 16.1 0.0 0.045 14.0 0.0 2.2 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 KPI44821.1 - 0.014 14.5 0.1 0.068 12.3 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Torsin PF06309.6 KPI44821.1 - 0.015 15.1 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Torsin PhoH PF02562.11 KPI44821.1 - 0.029 13.5 0.0 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.1 KPI44821.1 - 0.031 14.2 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KPI44821.1 - 0.036 13.7 0.1 0.15 11.6 0.0 2.1 2 1 0 2 2 2 0 NACHT domain RuvB_N PF05496.7 KPI44821.1 - 0.04 12.9 0.0 0.09 11.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus MobB PF03205.9 KPI44821.1 - 0.062 13.0 0.0 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Parvo_NS1 PF01057.12 KPI44821.1 - 0.074 11.9 0.0 0.19 10.5 0.0 1.6 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 AFG1_ATPase PF03969.11 KPI44821.1 - 0.089 11.5 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase AAA_3 PF07726.6 KPI44821.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4554 PF15091.1 KPI44821.1 - 3.2 6.3 5.0 7.6 5.1 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) FlxA PF14282.1 KPI44822.1 - 1.4 8.8 8.7 0.059 13.3 1.7 1.9 2 0 0 2 2 2 0 FlxA-like protein Scytalone_dh PF02982.9 KPI44823.1 - 3e-84 280.4 3.3 3.6e-84 280.1 2.3 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 KPI44823.1 - 7.4e-07 29.1 0.3 9.5e-07 28.7 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain Cupin_7 PF12973.2 KPI44824.1 - 8e-09 35.2 0.1 1e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain DUF4437 PF14499.1 KPI44824.1 - 0.0027 16.6 0.1 0.0027 16.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4437) Cupin_2 PF07883.6 KPI44824.1 - 0.0033 16.9 0.4 0.0058 16.1 0.2 1.4 1 0 0 1 1 1 1 Cupin domain Complex1_LYR_2 PF13233.1 KPI44825.1 - 2.4e-08 34.3 0.5 2.9e-08 34.1 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KPI44825.1 - 5e-05 23.0 0.1 8.5e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KPI44825.1 - 8.9e-05 22.6 0.2 0.00013 22.0 0.1 1.4 1 1 0 1 1 1 1 Complex1_LYR-like DUF3135 PF11333.3 KPI44825.1 - 0.036 14.2 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) SNARE PF05739.14 KPI44826.1 - 0.0013 18.3 0.3 0.0013 18.3 0.2 3.1 2 1 0 2 2 2 1 SNARE domain ATP-synt_E PF05680.7 KPI44826.1 - 3.1 7.8 9.9 0.29 11.1 0.9 2.9 3 0 0 3 3 3 0 ATP synthase E chain Mito_carr PF00153.22 KPI44828.1 - 3.8e-46 154.7 10.5 4.4e-18 64.7 0.1 3.6 3 1 1 4 4 4 3 Mitochondrial carrier protein DRMBL PF07522.9 KPI44830.1 - 1.1e-29 102.7 0.0 2e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KPI44830.1 - 6.6e-10 38.8 0.1 1.9e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Dec-1 PF04624.9 KPI44830.1 - 0.26 10.9 2.7 0.64 9.6 1.8 1.6 1 0 0 1 1 1 0 Dec-1 repeat MFS_1 PF07690.11 KPI44832.1 - 3.5e-31 108.2 34.4 4.6e-31 107.8 23.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF543 PF04418.7 KPI44833.1 - 5.1e-26 90.4 0.0 5.5e-26 90.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Mito_carr PF00153.22 KPI44835.1 - 5.2e-43 144.6 3.8 4.5e-21 74.3 0.1 2.6 3 0 0 3 3 3 2 Mitochondrial carrier protein SPO22 PF08631.5 KPI44836.1 - 3.3e-26 91.9 1.9 2.7e-25 88.9 0.1 3.1 4 0 0 4 4 4 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 KPI44836.1 - 5.7e-07 29.3 6.7 0.031 14.2 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat tRNA-synt_His PF13393.1 KPI44837.1 - 1.5e-35 122.7 0.0 1.2e-29 103.3 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KPI44837.1 - 8.6e-15 54.7 0.0 1.5e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KPI44837.1 - 0.00012 21.9 0.1 0.00026 20.8 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain Ribosomal_60s PF00428.14 KPI44837.1 - 0.045 14.1 0.3 0.12 12.7 0.2 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein CVNH PF08881.5 KPI44838.1 - 3.5e-30 104.2 0.3 6.1e-30 103.5 0.2 1.4 1 0 0 1 1 1 1 CVNH domain Gly-zipper_OmpA PF13436.1 KPI44838.1 - 0.00024 20.7 1.1 0.001 18.7 0.8 2.1 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Rick_17kDa_Anti PF05433.10 KPI44838.1 - 0.00067 19.2 14.1 0.00067 19.2 9.8 2.0 2 0 0 2 2 2 1 Glycine zipper 2TM domain SR-25 PF10500.4 KPI44838.1 - 0.0014 18.1 18.5 0.0024 17.3 12.8 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Gly-zipper_Omp PF13488.1 KPI44838.1 - 0.0027 17.2 11.2 0.0027 17.2 7.8 2.2 3 0 0 3 3 3 1 Glycine zipper Ebp2 PF05890.7 KPI44838.1 - 0.016 14.5 11.5 0.026 13.8 8.0 1.2 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 TFIIF_alpha PF05793.7 KPI44838.1 - 0.26 9.6 11.5 0.39 9.0 7.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF533 PF04391.7 KPI44838.1 - 1.2 8.4 6.7 0.076 12.3 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Rtf2 PF04641.7 KPI44838.1 - 2.3 7.3 8.9 3.3 6.8 6.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C2H2_4 PF13894.1 KPI44840.1 - 0.0077 16.4 0.2 0.2 12.0 0.0 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-SNAP50_C PF12251.3 KPI44840.1 - 0.045 13.1 2.0 0.07 12.5 1.4 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal ADH_zinc_N PF00107.21 KPI44841.1 - 2.3e-11 43.3 0.7 3.9e-11 42.6 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI44841.1 - 8.9e-11 41.5 0.1 4.8e-09 35.9 0.1 2.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KPI44841.1 - 9.8e-07 29.7 0.0 2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KPI44841.1 - 0.017 14.3 0.1 0.027 13.6 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KPI44841.1 - 0.082 12.4 0.2 0.13 11.8 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain EthD PF07110.6 KPI44842.1 - 3.3e-21 76.0 0.0 7.8e-13 49.1 0.0 2.2 2 0 0 2 2 2 2 EthD domain DUF4449 PF14613.1 KPI44843.1 - 1.6e-05 24.9 4.7 1.6e-05 24.8 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) DUF3453 PF11935.3 KPI44843.1 - 0.032 13.6 0.8 1 8.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3453) Tricorn_C1 PF14684.1 KPI44843.1 - 0.14 12.0 0.5 1.3 8.9 0.0 2.6 3 0 0 3 3 3 0 Tricorn protease C1 domain G6PD_C PF02781.11 KPI44844.1 - 2e-134 447.0 0.0 2.8e-134 446.5 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KPI44844.1 - 5.6e-65 219.0 0.1 9.9e-65 218.1 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Sugar_tr PF00083.19 KPI44847.1 - 3.9e-73 246.5 28.7 1.9e-70 237.7 19.9 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI44847.1 - 1.1e-18 67.0 30.0 4.5e-17 61.8 12.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.8 KPI44848.1 - 3.6e-05 23.9 0.2 0.00089 19.3 0.1 2.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.13 KPI44850.1 - 1e-14 54.0 0.5 1e-14 54.0 0.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI44850.1 - 3.6e-05 23.5 6.2 7.2e-05 22.6 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTPase_Cys_C PF12631.2 KPI44850.1 - 0.13 12.6 0.7 0.72 10.3 0.0 2.5 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE DUF377 PF04041.8 KPI44851.1 - 2.6e-46 157.7 0.0 6.2e-46 156.5 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF377) Glyco_hydro_43 PF04616.9 KPI44851.1 - 1.7e-08 33.9 0.4 0.00011 21.3 0.1 3.1 3 1 0 3 3 3 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KPI44851.1 - 1.2e-07 31.3 0.9 4.4e-05 22.9 0.0 3.0 3 0 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain HET PF06985.6 KPI44852.1 - 1.6e-32 112.5 5.0 2.6e-32 111.8 3.5 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ras PF00071.17 KPI44854.1 - 2.9e-53 179.5 0.3 2.5e-52 176.5 0.2 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KPI44854.1 - 6.3e-17 62.1 0.0 8.1e-15 55.3 0.0 2.2 1 1 1 2 2 2 1 Miro-like protein Arf PF00025.16 KPI44854.1 - 0.00013 21.2 0.0 0.00065 18.9 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KPI44854.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KPI44854.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KPI44854.1 - 0.062 12.5 0.0 0.79 8.9 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.1 KPI44854.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 KPI44854.1 - 0.071 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Septin GTP_EFTU PF00009.22 KPI44854.1 - 0.08 12.3 0.0 2.9 7.2 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Nfu_N PF08712.6 KPI44855.1 - 9.3e-27 92.4 0.0 3e-26 90.8 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KPI44855.1 - 2.1e-20 72.2 0.1 3.5e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain MutS_III PF05192.13 KPI44856.1 - 0.044 13.5 3.0 0.083 12.6 2.1 1.5 1 0 0 1 1 1 0 MutS domain III GAT PF03127.9 KPI44856.1 - 0.085 12.8 3.5 0.12 12.3 0.3 2.6 2 1 0 2 2 2 0 GAT domain Flagellin_C PF00700.16 KPI44856.1 - 2.2 8.5 8.4 9 6.5 0.1 3.2 2 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region Pyr_redox_2 PF07992.9 KPI44858.1 - 7.2e-17 61.9 0.2 3.2e-16 59.7 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KPI44858.1 - 3.5e-07 30.4 1.3 0.004 17.2 0.2 2.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI44858.1 - 2.3e-05 24.2 2.2 0.033 13.9 0.0 2.6 2 1 1 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 KPI44858.1 - 0.00068 18.6 0.2 1.1 8.1 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KPI44858.1 - 0.0016 17.9 0.2 0.034 13.7 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 KPI44858.1 - 0.026 14.9 6.7 1.4 9.3 0.9 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 KPI44858.1 - 0.086 11.9 0.4 0.42 9.7 0.0 2.1 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KPI44858.1 - 0.12 12.6 3.3 0.21 11.8 0.0 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding SSFA2_C PF14723.1 KPI44859.1 - 0.049 13.3 0.2 0.095 12.4 0.2 1.5 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus EthD PF07110.6 KPI44860.1 - 2.4e-17 63.6 1.3 3.3e-17 63.1 0.9 1.2 1 0 0 1 1 1 1 EthD domain zf-DHHC PF01529.15 KPI44861.1 - 0.00069 19.0 0.3 0.00087 18.7 0.2 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase PKD_channel PF08016.7 KPI44861.1 - 0.11 10.9 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Polycystin cation channel Ferritin_2 PF13668.1 KPI44862.1 - 3.5e-08 33.4 0.0 5.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Xpo1 PF08389.7 KPI44863.1 - 4.8e-35 120.6 0.6 4.8e-35 120.6 0.4 3.6 4 0 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.17 KPI44863.1 - 0.0037 17.2 1.7 2.3 8.5 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat BP28CT PF08146.7 KPI44863.1 - 0.11 12.2 2.3 1.1 9.0 0.1 3.2 3 0 0 3 3 3 0 BP28CT (NUC211) domain MFS_1 PF07690.11 KPI44864.1 - 1.7e-26 92.8 39.1 1.1e-25 90.1 27.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KPI44864.1 - 0.00013 20.1 3.0 0.039 12.0 0.2 3.3 4 0 0 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family DUF912 PF06024.7 KPI44864.1 - 0.023 14.7 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CcmH PF03918.9 KPI44864.1 - 0.14 11.1 2.6 18 4.2 0.3 3.4 3 0 0 3 3 3 0 Cytochrome C biogenesis protein Fungal_trans_2 PF11951.3 KPI44865.1 - 5.7e-05 21.8 0.1 0.0001 21.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_2 PF13639.1 KPI44866.1 - 0.0098 15.7 1.2 0.0098 15.7 0.9 2.0 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KPI44866.1 - 0.01 15.5 2.3 0.052 13.2 0.4 2.3 2 1 0 2 2 2 0 zinc-RING finger domain Syntaxin-18_N PF10496.4 KPI44866.1 - 0.062 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus Prok-RING_1 PF14446.1 KPI44866.1 - 0.099 12.3 3.0 0.7 9.6 0.0 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.1 KPI44866.1 - 0.6 10.1 0.0 0.6 10.1 0.0 2.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF4448 PF14610.1 KPI44867.1 - 0.00031 20.2 0.0 0.00059 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 KPI44867.1 - 0.021 14.1 0.6 0.044 13.0 0.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MFS_1 PF07690.11 KPI44868.1 - 8.8e-14 50.9 24.7 1.3e-13 50.4 17.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI44868.1 - 8.3e-13 47.7 13.9 1.2e-12 47.2 9.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TspO_MBR PF03073.10 KPI44870.1 - 5.1e-37 126.6 7.1 6.5e-37 126.3 4.0 1.7 1 1 1 2 2 2 1 TspO/MBR family Tautomerase_3 PF14832.1 KPI44871.1 - 3.2e-12 46.6 0.4 1.8e-11 44.1 0.3 2.0 1 1 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 KPI44871.1 - 1.7e-05 24.3 0.0 3.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Tautomerase enzyme zf-C2H2_4 PF13894.1 KPI44872.1 - 1.2e-08 34.6 29.9 0.0009 19.4 0.1 7.3 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI44872.1 - 3.7e-08 33.2 4.0 5.7e-05 23.2 0.1 6.4 7 0 0 7 7 7 2 Zinc finger, C2H2 type Band_7 PF01145.20 KPI44873.1 - 1.6e-16 60.7 0.4 1.6e-16 60.7 0.3 2.7 2 1 0 2 2 2 1 SPFH domain / Band 7 family FAD-oxidase_C PF02913.14 KPI44874.1 - 8.5e-33 113.6 0.0 1.2e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KPI44874.1 - 1.1e-28 99.5 0.1 2.3e-28 98.4 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain SRI PF08236.6 KPI44876.1 - 1.9e-21 75.7 11.5 1.9e-21 75.7 8.0 2.1 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 KPI44876.1 - 3e-21 76.3 0.6 3e-21 76.3 0.4 3.5 2 2 0 2 2 2 1 SET domain WW PF00397.21 KPI44876.1 - 0.0014 18.4 0.2 0.0035 17.1 0.1 1.7 1 0 0 1 1 1 1 WW domain Mak10 PF04112.8 KPI44876.1 - 0.14 11.4 2.0 0.26 10.5 0.9 1.8 2 0 0 2 2 2 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase TMEM171 PF15471.1 KPI44876.1 - 0.34 9.6 1.7 0.79 8.4 1.2 1.6 1 0 0 1 1 1 0 Transmembrane protein family 171 AIPR PF10592.4 KPI44876.1 - 3.3 6.9 8.7 0.46 9.7 3.0 1.7 2 0 0 2 2 2 0 AIPR protein Abhydrolase_6 PF12697.2 KPI44877.1 - 5.3e-15 55.9 0.5 6.1e-13 49.1 0.1 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI44877.1 - 6.3e-08 32.4 0.0 4.9e-06 26.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI44877.1 - 1.9e-07 30.9 0.0 3.7e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI44877.1 - 5.8e-05 22.4 0.1 0.13 11.4 0.0 2.8 3 1 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.13 KPI44877.1 - 0.0011 18.2 0.0 0.026 13.7 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 KPI44877.1 - 0.0069 16.2 0.0 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein FAD_binding_3 PF01494.14 KPI44878.1 - 1.6e-23 83.3 0.2 2.3e-22 79.5 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 KPI44878.1 - 0.0003 19.7 0.0 0.00048 19.0 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 KPI44878.1 - 0.00062 18.7 0.1 0.085 11.7 0.0 2.6 2 1 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.19 KPI44878.1 - 0.0025 16.7 0.0 0.0052 15.7 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KPI44878.1 - 0.02 14.6 0.1 0.14 11.9 0.0 2.2 1 1 1 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 KPI44878.1 - 0.069 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Glyco_hydro_16 PF00722.16 KPI44879.1 - 1.9e-20 72.9 2.6 3.6e-20 72.0 1.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Na_Ca_ex PF01699.19 KPI44880.1 - 1.5e-24 86.2 18.1 1.7e-16 60.1 2.0 2.5 1 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.7 KPI44880.1 - 0.00019 21.2 0.5 0.00075 19.3 0.4 2.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) DUF3169 PF11368.3 KPI44880.1 - 0.032 13.4 2.0 0.14 11.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF4173 PF13777.1 KPI44880.1 - 0.044 13.0 0.5 0.044 13.0 0.3 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4173) DUF3357 PF11837.3 KPI44880.1 - 0.82 9.5 2.3 3.8 7.4 0.1 3.2 2 1 2 4 4 4 0 Domain of unknown function (DUF3357) GalKase_gal_bdg PF10509.4 KPI44882.1 - 0.0046 16.2 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature DUF4381 PF14316.1 KPI44882.1 - 0.038 14.1 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Herpes_gE PF02480.11 KPI44882.1 - 0.045 12.0 0.0 0.062 11.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KPI44882.1 - 0.16 12.3 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 KPI44882.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF1341 PF07071.6 KPI44882.1 - 0.2 11.1 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1341) SSP160 PF06933.6 KPI44882.1 - 0.98 7.3 5.1 1.3 6.8 3.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MFS_1 PF07690.11 KPI44883.1 - 7.7e-31 107.0 28.7 7.7e-31 107.0 19.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KPI44883.1 - 0.017 13.2 1.9 0.036 12.1 1.3 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SMC_N PF02463.14 KPI44885.1 - 1.4e-21 76.7 0.0 3.3e-21 75.5 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KPI44885.1 - 1.1e-11 45.4 55.5 8.1e-10 39.3 21.8 5.0 3 2 0 3 3 2 2 AAA domain AAA_21 PF13304.1 KPI44885.1 - 0.00037 20.5 0.0 0.00092 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KPI44885.1 - 0.00061 19.2 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF812 PF05667.6 KPI44885.1 - 0.0023 16.5 0.6 0.0023 16.5 0.4 4.2 2 2 1 4 4 4 1 Protein of unknown function (DUF812) Reo_sigmaC PF04582.7 KPI44885.1 - 0.0045 16.2 0.1 3.8 6.5 0.0 2.9 3 0 0 3 3 3 2 Reovirus sigma C capsid protein Mnd1 PF03962.10 KPI44885.1 - 0.0083 15.8 1.0 0.0083 15.8 0.7 6.1 3 2 1 5 5 3 1 Mnd1 family CENP-F_leu_zip PF10473.4 KPI44885.1 - 0.017 15.0 0.8 0.017 15.0 0.6 6.5 4 1 1 5 5 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 KPI44885.1 - 0.02 14.6 0.4 0.02 14.6 0.3 6.0 5 1 1 6 6 6 0 Laminin Domain II AAA_25 PF13481.1 KPI44885.1 - 0.021 14.1 2.1 0.031 13.6 0.0 2.4 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.1 KPI44885.1 - 0.027 15.2 0.1 0.027 15.2 0.0 3.8 2 2 0 3 3 3 0 AAA domain AAA_15 PF13175.1 KPI44885.1 - 0.027 13.5 0.3 0.14 11.1 0.2 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 KPI44885.1 - 0.038 13.7 0.6 0.28 10.9 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain BLOC1_2 PF10046.4 KPI44885.1 - 0.11 12.6 0.1 0.11 12.6 0.1 6.3 6 1 0 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 KPI44885.1 - 0.75 8.1 58.4 0.058 11.8 0.5 5.0 4 2 0 4 4 4 0 AAA domain AAA_22 PF13401.1 KPI44885.1 - 2.6 8.1 6.3 3.2 7.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain Baculo_PEP_C PF04513.7 KPI44885.1 - 6.7 6.5 10.4 9.4 6.0 0.0 4.3 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus GPI-anchored PF10342.4 KPI44887.1 - 1.4e-17 63.9 0.1 1.4e-17 63.9 0.1 2.9 1 1 2 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Macoilin PF09726.4 KPI44887.1 - 9.1 4.4 7.4 10 4.2 5.1 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF4066 PF13278.1 KPI44888.1 - 1.6e-17 63.2 0.0 2e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KPI44888.1 - 3.6e-08 32.9 0.0 5.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Ribonuclease PF00545.15 KPI44890.1 - 2.7e-05 24.1 0.0 3.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 ribonuclease Mito_fiss_reg PF05308.6 KPI44890.1 - 8 5.7 10.5 12 5.2 7.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator COPIIcoated_ERV PF07970.7 KPI44891.1 - 9.9e-70 234.6 0.1 1.1e-46 159.1 0.0 2.3 2 0 0 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KPI44891.1 - 7.8e-34 115.5 0.0 2.9e-33 113.6 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) MFS_1 PF07690.11 KPI44892.1 - 4.5e-07 28.9 41.0 4.5e-07 28.9 28.4 2.9 1 1 0 2 2 2 1 Major Facilitator Superfamily bZIP_1 PF00170.16 KPI44894.1 - 0.00051 19.9 4.6 0.0012 18.7 3.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor Myotub-related PF06602.9 KPI44894.1 - 0.13 11.0 0.2 0.18 10.5 0.1 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Med24_N PF11277.3 KPI44894.1 - 0.2 9.1 0.0 0.32 8.4 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal DUF1501 PF07394.7 KPI44894.1 - 0.36 9.6 3.8 0.62 8.8 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF2265 PF10023.4 KPI44894.1 - 0.83 8.7 3.4 1.2 8.1 2.4 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) bZIP_2 PF07716.10 KPI44894.1 - 1.6 8.6 13.4 0.74 9.6 3.6 2.3 2 0 0 2 2 2 0 Basic region leucine zipper PSP1 PF04468.7 KPI44895.1 - 2.7e-29 101.0 1.4 5e-29 100.1 1.0 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF846 PF05832.7 KPI44896.1 - 1.7e-44 150.9 9.7 2.1e-44 150.6 6.7 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Tic20 PF09685.5 KPI44896.1 - 8.5 6.4 15.7 0.88 9.5 1.9 2.2 2 0 0 2 2 2 0 Tic20-like protein zf-C2H2_4 PF13894.1 KPI44897.1 - 0.016 15.5 1.0 0.016 15.5 0.7 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger FMN_dh PF01070.13 KPI44898.1 - 1.8e-119 398.8 0.0 3.2e-119 397.9 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ABC_membrane PF00664.18 KPI44898.1 - 1.5e-71 241.0 33.0 2.4e-36 125.5 9.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KPI44898.1 - 2.5e-62 209.2 0.0 1.7e-33 115.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KPI44898.1 - 2e-12 47.6 0.0 0.014 15.3 0.0 4.3 3 1 0 4 4 4 2 AAA domain ABC_ATPase PF09818.4 KPI44898.1 - 2.7e-11 42.7 0.3 0.00055 18.6 0.0 3.9 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KPI44898.1 - 2.9e-11 43.6 2.4 1.2e-06 28.6 0.1 2.6 2 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 KPI44898.1 - 6.5e-11 41.8 1.6 0.00018 20.7 0.6 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KPI44898.1 - 7.7e-09 35.7 0.2 0.00052 20.1 0.0 3.4 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KPI44898.1 - 1.6e-08 33.8 0.0 0.0025 17.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KPI44898.1 - 1.3e-06 27.8 1.0 0.0065 15.9 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain IMPDH PF00478.20 KPI44898.1 - 1.4e-06 27.4 1.8 1.9e-05 23.7 0.1 2.6 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain SbcCD_C PF13558.1 KPI44898.1 - 1.1e-05 25.2 0.6 0.3 11.0 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 KPI44898.1 - 1.8e-05 25.5 0.0 0.14 12.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KPI44898.1 - 1.8e-05 24.2 0.2 0.18 11.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.1 KPI44898.1 - 2.6e-05 23.8 0.0 0.11 12.0 0.0 3.4 3 1 0 3 3 3 1 AAA domain Glu_synthase PF01645.12 KPI44898.1 - 7.5e-05 21.8 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase AAA_5 PF07728.9 KPI44898.1 - 0.00014 21.6 0.2 0.84 9.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA PF00004.24 KPI44898.1 - 0.00024 21.3 1.4 0.97 9.6 0.0 4.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KPI44898.1 - 0.001 18.9 0.1 1.7 8.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KPI44898.1 - 0.0019 18.1 0.8 1.5 8.7 0.1 2.9 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 KPI44898.1 - 0.0034 17.2 0.1 11 5.9 0.0 3.8 4 0 0 4 4 3 0 AAA domain MobB PF03205.9 KPI44898.1 - 0.0047 16.6 0.1 3.9 7.1 0.0 3.2 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KPI44898.1 - 0.0068 15.8 1.7 3.6 6.9 0.0 3.3 3 1 1 4 4 3 1 AAA-like domain AAA_18 PF13238.1 KPI44898.1 - 0.01 16.1 0.1 8.8 6.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.20 KPI44898.1 - 0.011 15.3 0.4 0.92 8.9 0.0 3.1 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain His_biosynth PF00977.16 KPI44898.1 - 0.011 15.0 0.0 0.054 12.7 0.0 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein MMR_HSR1 PF01926.18 KPI44898.1 - 0.011 15.6 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 KPI44898.1 - 0.012 15.7 0.1 8.4 6.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.12 KPI44898.1 - 0.025 14.1 0.0 1.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Rad17 PF03215.10 KPI44898.1 - 0.065 11.9 0.3 1.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NACHT PF05729.7 KPI44898.1 - 0.084 12.5 0.2 5.2 6.6 0.1 2.6 2 0 0 2 2 2 0 NACHT domain GRAM PF02893.15 KPI44898.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 GRAM domain DUF87 PF01935.12 KPI44898.1 - 0.15 11.8 0.1 3 7.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 Adeno_IVa2 PF02456.10 KPI44898.1 - 0.18 10.4 0.0 0.98 7.9 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_15 PF13175.1 KPI44898.1 - 0.77 8.7 0.0 7.8 5.4 0.0 2.2 3 0 0 3 3 2 0 AAA ATPase domain AAA_23 PF13476.1 KPI44898.1 - 0.83 9.9 0.7 54 4.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain Drf_GBD PF06371.8 KPI44899.1 - 0.0042 16.4 0.9 0.024 13.9 0.2 2.4 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Med13_C PF06333.7 KPI44900.1 - 0.11 10.9 0.3 0.12 10.8 0.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal DUF3824 PF12868.2 KPI44901.1 - 3.7e-05 24.6 66.5 0.0016 19.3 30.4 9.4 7 4 3 10 10 10 3 Domain of unknwon function (DUF3824) Aldo_ket_red PF00248.16 KPI44902.1 - 8.4e-43 146.2 0.1 1e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NDUFA12 PF05071.11 KPI44903.1 - 8.5e-14 51.8 1.8 8.5e-14 51.8 1.2 1.4 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF867 PF05908.6 KPI44904.1 - 0.0095 15.0 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF867) AbfB PF05270.8 KPI44904.1 - 0.032 13.9 0.1 0.037 13.7 0.1 1.1 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B (ABFB) Trans_reg_C PF00486.23 KPI44904.1 - 0.073 12.9 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal ABM PF03992.11 KPI44904.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Myb_DNA-binding PF00249.26 KPI44905.1 - 2e-05 24.5 0.6 4e-05 23.5 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KPI44905.1 - 0.022 14.8 1.9 0.048 13.7 1.3 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain 2-Hacid_dh_C PF02826.14 KPI44906.1 - 2.7e-52 176.4 0.0 3.5e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KPI44906.1 - 1.3e-19 69.9 0.0 1.6e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KPI44906.1 - 0.00017 21.4 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 KPI44906.1 - 0.00045 20.7 0.0 0.001 19.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 KPI44906.1 - 0.051 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KPI44906.1 - 0.088 12.8 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain PRKCSH PF07915.8 KPI44907.1 - 2e-18 66.9 1.0 3.6e-18 66.1 0.1 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 KPI44907.1 - 0.025 14.0 0.1 0.085 12.3 0.0 1.9 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein FMN_bind_2 PF04299.7 KPI44908.1 - 6.5e-44 149.4 0.1 1.4e-43 148.3 0.1 1.5 1 1 0 1 1 1 1 Putative FMN-binding domain SNF2_N PF00176.18 KPI44909.1 - 5.3e-58 196.1 0.2 7.7e-58 195.6 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KPI44909.1 - 1.2e-08 35.0 0.1 3.3e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KPI44909.1 - 9.1e-06 25.2 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1296 PF06972.6 KPI44909.1 - 0.025 14.5 0.2 0.08 12.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) ADH_N PF08240.7 KPI44910.1 - 4e-22 78.0 4.3 8e-22 77.0 3.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI44910.1 - 4.6e-17 61.7 0.2 2e-16 59.7 0.1 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KPI44910.1 - 9.1e-06 24.9 0.2 1.9e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KPI44910.1 - 0.00074 19.1 0.6 0.0015 18.0 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KPI44910.1 - 0.0062 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.10 KPI44910.1 - 0.0089 15.8 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ATP-synt_E PF05680.7 KPI44911.1 - 1.7e-21 75.9 0.0 1.8e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 ATP synthase E chain 4HBT_2 PF13279.1 KPI44912.1 - 2.5e-08 34.3 0.0 3.9e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily BLOC1_2 PF10046.4 KPI44912.1 - 0.078 13.1 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MMR_HSR1 PF01926.18 KPI44913.1 - 8.2e-08 32.2 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KPI44913.1 - 0.00069 18.8 0.0 0.0017 17.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KPI44913.1 - 0.0013 19.1 0.2 0.0055 17.2 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 KPI44913.1 - 0.0041 17.2 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KPI44913.1 - 0.014 16.1 0.0 0.014 16.1 0.0 2.7 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.1 KPI44913.1 - 0.016 15.5 0.0 0.016 15.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.7 KPI44913.1 - 0.032 13.5 0.1 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_24 PF13479.1 KPI44913.1 - 0.034 13.7 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 KPI44913.1 - 0.038 12.8 3.8 0.097 11.4 0.0 2.1 2 0 0 2 2 2 0 MCM2/3/5 family FeoB_N PF02421.13 KPI44913.1 - 0.066 12.4 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B Ras PF00071.17 KPI44913.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Ras family ABC_tran PF00005.22 KPI44913.1 - 0.12 12.6 0.1 0.12 12.6 0.1 2.7 2 2 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 KPI44913.1 - 0.18 11.7 0.0 0.18 11.7 0.0 2.3 2 1 0 2 2 1 0 AAA ATPase domain AAA_33 PF13671.1 KPI44913.1 - 0.67 9.8 6.6 0.92 9.3 0.0 2.9 2 1 2 4 4 4 0 AAA domain AAA_23 PF13476.1 KPI44913.1 - 2.2 8.5 11.4 20 5.4 6.9 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KPI44913.1 - 2.6 7.8 4.9 12 5.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 BTV_NS2 PF04514.7 KPI44913.1 - 3 6.6 16.4 4.2 6.1 11.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Glyoxalase_2 PF12681.2 KPI44914.1 - 4.6e-10 40.0 0.0 6.1e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KPI44914.1 - 0.02 14.8 0.1 0.17 11.8 0.1 2.1 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Toxin_33 PF08121.6 KPI44914.1 - 1.1 8.8 4.0 5.4 6.6 0.4 2.3 2 0 0 2 2 2 0 Waglerin family SpoIIE PF07228.7 KPI44915.1 - 4.2e-13 49.4 0.0 5.1e-12 45.8 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KPI44915.1 - 2.4e-09 36.9 0.0 4.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KPI44915.1 - 6.3e-09 35.6 0.1 0.0016 17.8 0.1 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Methyltransf_23 PF13489.1 KPI44916.1 - 3.1e-17 62.7 0.0 4.1e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI44916.1 - 6.1e-13 49.0 0.0 1.2e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI44916.1 - 4.2e-12 46.6 0.0 6.9e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI44916.1 - 4.4e-12 45.8 0.0 2e-11 43.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI44916.1 - 1.9e-10 41.0 0.0 2e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KPI44916.1 - 6.2e-05 22.1 0.0 8.8e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 KPI44916.1 - 6.7e-05 23.1 0.0 0.00019 21.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KPI44916.1 - 0.00014 21.3 0.0 0.00025 20.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KPI44916.1 - 0.00028 20.3 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 KPI44916.1 - 0.00045 19.6 0.0 0.0018 17.6 0.0 1.8 2 0 0 2 2 2 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 KPI44916.1 - 0.052 12.6 0.0 4.5 6.3 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family tRNA_U5-meth_tr PF05958.6 KPI44916.1 - 0.06 12.0 0.0 0.08 11.6 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TehB PF03848.9 KPI44916.1 - 0.062 12.4 0.0 0.14 11.3 0.0 1.5 2 0 0 2 2 2 0 Tellurite resistance protein TehB PCMT PF01135.14 KPI44916.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KPI44916.1 - 0.088 12.4 0.0 0.21 11.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KPI44916.1 - 0.094 12.7 0.1 0.36 10.8 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain DREV PF05219.7 KPI44916.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase PrmA PF06325.8 KPI44916.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AA_permease_2 PF13520.1 KPI44917.1 - 8.1e-59 199.2 56.6 9.8e-59 198.9 39.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI44917.1 - 5.8e-22 77.6 48.1 7.8e-22 77.2 33.4 1.1 1 0 0 1 1 1 1 Amino acid permease AKAP7_NLS PF10469.4 KPI44919.1 - 9.8e-21 74.4 0.0 3e-14 53.2 0.0 2.2 2 0 0 2 2 2 2 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 KPI44919.1 - 3.1e-08 33.4 0.3 8.2e-08 32.1 0.1 1.8 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 KPI44919.1 - 0.00015 21.6 0.5 0.066 13.1 0.0 3.5 3 0 0 3 3 3 1 LigT like Phosphoesterase SSP160 PF06933.6 KPI44919.1 - 0.35 8.8 2.5 0.55 8.1 1.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 OB_NTP_bind PF07717.11 KPI44921.1 - 1.4e-29 102.1 0.0 3.4e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KPI44921.1 - 1.1e-23 83.2 0.0 1.1e-23 83.2 0.0 2.4 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KPI44921.1 - 1.4e-11 44.0 0.0 3.3e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KPI44921.1 - 1.1e-06 28.3 0.1 2.7e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KPI44921.1 - 5.3e-05 23.3 0.0 0.0002 21.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KPI44921.1 - 0.00032 19.6 0.0 0.00071 18.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 KPI44921.1 - 0.015 15.0 1.7 0.067 12.9 0.0 3.0 4 0 0 4 4 4 0 Part of AAA domain Sigma54_activ_2 PF14532.1 KPI44921.1 - 0.024 14.6 0.0 0.084 12.9 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 KPI44921.1 - 0.043 13.3 0.1 0.28 10.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.17 KPI44921.1 - 0.049 13.0 0.2 0.12 11.7 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 KPI44921.1 - 0.06 13.6 2.5 0.85 9.9 0.1 3.7 3 1 1 4 4 4 0 ABC transporter AAA_23 PF13476.1 KPI44921.1 - 0.28 11.5 0.0 0.28 11.5 0.0 3.1 1 1 0 2 2 1 0 AAA domain dCMP_cyt_deam_1 PF00383.17 KPI44922.1 - 5.1e-08 32.4 1.1 2.2e-07 30.4 0.8 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 KPI44922.1 - 0.00024 21.1 0.1 0.0031 17.5 0.1 2.2 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Frankia_peptide PF14407.1 KPI44922.1 - 0.08 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. LmjF365940-deam PF14421.1 KPI44922.1 - 0.086 12.2 2.6 2.8 7.2 0.1 2.2 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases UPF0261 PF06792.6 KPI44923.1 - 3e-40 137.9 0.1 3.6e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) PRT_C PF08372.5 KPI44925.1 - 0.00037 20.0 2.2 0.24 10.8 0.1 2.9 2 1 1 3 3 3 2 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.12 KPI44925.1 - 0.0033 17.0 2.1 0.76 9.3 0.0 2.3 2 0 0 2 2 2 2 Reticulon Pex24p PF06398.6 KPI44925.1 - 0.032 13.0 3.3 0.055 12.2 2.3 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin WHEP-TRS PF00458.15 KPI44925.1 - 0.083 12.5 0.4 0.4 10.3 0.4 2.1 2 0 0 2 2 2 0 WHEP-TRS domain T_cell_tran_alt PF15128.1 KPI44925.1 - 0.12 11.8 1.1 13 5.3 0.1 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Cupin_2 PF07883.6 KPI44926.1 - 7e-12 44.6 0.2 1.2e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.13 KPI44926.1 - 0.019 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Atg14 PF10186.4 KPI44927.1 - 4.2e-55 186.8 0.0 6.5e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 tRNA-synt_2c PF01411.14 KPI44928.1 - 1.8e-211 703.2 0.0 3e-211 702.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KPI44928.1 - 6.2e-18 64.4 1.4 1.8e-17 62.9 0.9 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CTK3_C PF12350.3 KPI44929.1 - 7.4e-09 35.5 2.2 1.6e-08 34.4 1.5 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus LRR_4 PF12799.2 KPI44929.1 - 8e-08 31.7 11.9 2.9e-06 26.7 2.3 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) TAP_C PF03943.8 KPI44929.1 - 6.6e-06 25.4 1.0 1.1e-05 24.7 0.1 1.8 2 0 0 2 2 2 1 TAP C-terminal domain LRR_6 PF13516.1 KPI44929.1 - 8.3e-05 22.2 3.6 0.03 14.3 0.6 3.2 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.1 KPI44929.1 - 0.00028 20.5 0.6 0.00068 19.3 0.4 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 KPI44929.1 - 0.00038 20.1 1.5 0.26 11.4 0.3 3.4 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_7 PF13504.1 KPI44929.1 - 0.083 13.1 4.9 0.091 13.0 0.4 3.1 4 0 0 4 4 4 0 Leucine rich repeat PAS_9 PF13426.1 KPI44930.1 - 2.8e-18 66.1 0.0 2.8e-17 63.0 0.0 2.3 2 0 0 2 2 2 1 PAS domain RGS PF00615.14 KPI44930.1 - 4.3e-13 49.4 0.1 1.4e-12 47.7 0.0 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain PAS PF00989.19 KPI44930.1 - 1.2e-05 25.0 0.0 3.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 KPI44930.1 - 0.0071 16.4 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 KPI44930.1 - 0.024 14.6 0.0 0.33 11.0 0.0 2.8 3 0 0 3 3 3 0 PAS fold PMT PF02366.13 KPI44931.1 - 2.3e-82 276.0 16.6 4.2e-82 275.1 11.5 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KPI44931.1 - 2.1e-15 56.7 1.2 4.3e-14 52.4 0.2 2.3 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 KPI44931.1 - 0.0074 16.1 13.6 0.0074 16.1 9.4 4.3 6 1 0 6 6 6 2 Dolichyl-phosphate-mannose-protein mannosyltransferase PLA2_B PF01735.13 KPI44932.1 - 2.9e-09 35.6 7.0 3.4e-09 35.4 4.9 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain BRAP2 PF07576.7 KPI44934.1 - 4.7e-23 80.8 0.0 8.6e-23 80.0 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 KPI44934.1 - 3.6e-20 71.8 3.1 1.1e-19 70.2 2.2 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 KPI44934.1 - 9.8e-11 41.3 9.7 9.8e-11 41.3 6.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KPI44934.1 - 1.6e-05 24.4 7.4 3.8e-05 23.2 5.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI44934.1 - 2.1e-05 24.1 6.8 2.1e-05 24.1 4.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KPI44934.1 - 4.1e-05 23.1 5.4 4.1e-05 23.1 3.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI44934.1 - 0.00014 21.8 8.9 0.00014 21.8 6.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KPI44934.1 - 0.00031 20.3 3.9 0.0017 18.0 2.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KPI44934.1 - 0.00094 19.2 5.0 0.0029 17.6 3.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KPI44934.1 - 0.0062 16.3 6.3 0.019 14.8 4.3 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 KPI44934.1 - 0.028 14.2 4.2 0.072 12.8 2.9 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-HC5HC2H PF13771.1 KPI44934.1 - 0.15 12.1 5.8 5.5 7.2 0.3 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain Baculo_RING PF05883.6 KPI44934.1 - 0.21 11.4 1.4 0.54 10.0 1.0 1.6 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain DUF4618 PF15397.1 KPI44934.1 - 0.47 9.7 9.4 0.52 9.5 5.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) zf-RING_4 PF14570.1 KPI44934.1 - 3.2 7.3 10.5 0.34 10.5 4.3 1.7 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain p450 PF00067.17 KPI44935.1 - 1.7e-70 237.8 0.0 1.9e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Helicase_C PF00271.26 KPI44936.1 - 2.4e-08 33.7 0.0 8.6e-08 31.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KPI44936.1 - 1.9e-06 27.4 0.1 3.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3505 PF12013.3 KPI44936.1 - 0.00025 21.2 0.4 0.0008 19.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) ResIII PF04851.10 KPI44936.1 - 0.076 12.8 0.0 1.2 8.8 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1390 PF07150.6 KPI44936.1 - 0.35 10.1 0.3 0.62 9.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) ADH_N PF08240.7 KPI44937.1 - 8.5e-07 28.7 0.5 1.5e-05 24.6 0.1 2.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain RNA_pol_A_bac PF01000.21 KPI44938.1 - 1.3e-15 57.5 0.0 3.1e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KPI44938.1 - 6.5e-14 50.8 0.0 1.5e-13 49.6 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain WD40 PF00400.27 KPI44940.1 - 3.1e-41 137.7 26.3 2.8e-11 42.8 0.2 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 KPI44940.1 - 1.2e-14 53.2 0.6 2.2e-14 52.4 0.4 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like zf-DHHC PF01529.15 KPI44941.1 - 2.9e-35 121.2 2.5 4.2e-35 120.6 1.7 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KPI44941.1 - 0.0079 15.9 0.4 0.083 12.6 1.1 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily DZR PF12773.2 KPI44941.1 - 0.58 10.0 11.0 0.98 9.2 7.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.21 KPI44942.1 - 6.6e-28 95.3 46.3 0.00018 21.6 0.1 9.8 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI44942.1 - 3.9e-18 64.3 41.8 0.0098 16.1 0.3 9.4 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KPI44942.1 - 2.8e-11 43.1 50.7 1.4e-05 25.1 0.6 9.6 10 1 0 10 10 10 5 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KPI44942.1 - 3.8e-09 36.4 11.4 4.1 7.6 0.0 7.3 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KPI44942.1 - 1e-05 25.5 5.2 6.1 7.1 0.0 6.3 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 KPI44942.1 - 2.5e-05 23.8 4.3 2.5 7.8 0.0 4.6 4 0 0 4 4 4 3 zinc-finger of a C2HC-type GAGA PF09237.6 KPI44942.1 - 0.035 13.7 3.4 0.13 11.8 0.0 2.8 3 0 0 3 3 3 0 GAGA factor Ogr_Delta PF04606.7 KPI44942.1 - 0.064 12.9 0.1 0.064 12.9 0.0 3.9 5 0 0 5 5 5 0 Ogr/Delta-like zinc finger HSP70 PF00012.15 KPI44943.1 - 5.4e-187 622.3 7.7 6e-187 622.2 5.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KPI44943.1 - 2.2e-15 56.1 0.1 3.4e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.11 KPI44943.1 - 0.0003 20.4 0.0 0.00058 19.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4473 PF14747.1 KPI44943.1 - 0.28 11.4 4.0 0.63 10.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) ATP-synt_DE PF00401.15 KPI44943.1 - 3.5 7.5 6.3 14 5.6 0.4 3.5 3 1 1 4 4 4 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain PIP5K PF01504.13 KPI44944.1 - 1.2e-82 276.8 0.0 1.7e-82 276.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SGL PF08450.7 KPI44945.1 - 2.7e-42 144.8 0.0 3.6e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 KPI44945.1 - 7.3e-08 31.9 0.0 2.2 8.3 0.0 5.3 5 0 0 5 5 5 3 NHL repeat Str_synth PF03088.11 KPI44945.1 - 3.1e-07 30.3 0.1 0.00051 20.0 0.0 3.4 3 2 0 3 3 3 2 Strictosidine synthase Arylesterase PF01731.15 KPI44945.1 - 1.2e-05 25.1 0.0 0.0017 18.3 0.0 3.7 3 1 1 4 4 4 1 Arylesterase Lactonase PF10282.4 KPI44945.1 - 0.00067 18.8 0.0 0.0014 17.8 0.0 1.5 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Acyl-CoA_dh_1 PF00441.19 KPI44946.1 - 9.9e-25 87.4 0.2 1.6e-24 86.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KPI44946.1 - 2.7e-21 76.2 0.0 4.6e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KPI44946.1 - 1.3e-17 62.9 0.0 2.6e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KPI44946.1 - 2.2e-07 31.1 0.0 3.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MMS19_C PF12460.3 KPI44947.1 - 6.8e-82 275.4 7.7 9e-82 275.0 5.4 1.2 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.1 KPI44947.1 - 7.6e-05 23.0 6.9 0.73 10.4 0.2 4.0 3 0 0 3 3 3 3 HEAT-like repeat HEAT_2 PF13646.1 KPI44947.1 - 7.6e-05 22.9 6.6 1.3 9.4 0.1 3.5 2 1 0 3 3 3 3 HEAT repeats HEAT PF02985.17 KPI44947.1 - 0.094 12.8 6.3 32 4.9 0.1 4.7 5 0 0 5 5 5 0 HEAT repeat Arm PF00514.18 KPI44947.1 - 0.15 11.9 4.2 0.88 9.4 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.20 KPI44948.1 - 2.1e-59 200.7 0.0 3.1e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI44948.1 - 1.8e-36 125.5 0.0 2.1e-34 118.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KPI44948.1 - 4.5e-10 38.9 0.0 1.1e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KPI44948.1 - 0.065 12.9 0.0 0.065 12.9 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Chitin_synth_2 PF03142.10 KPI44950.1 - 7.3e-267 885.9 3.9 7.3e-267 885.9 2.7 2.2 2 1 0 2 2 2 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 KPI44950.1 - 8.7e-14 51.8 0.0 1.3e-11 44.7 0.0 2.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KPI44950.1 - 5.2e-11 42.6 7.3 3.6e-10 39.8 5.0 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 KPI44950.1 - 0.0036 16.5 0.0 0.023 13.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KPI44950.1 - 0.075 12.7 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 UQ_con PF00179.21 KPI44951.1 - 9.9e-24 83.3 0.0 1.4e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KPI44951.1 - 0.0061 16.4 0.1 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 KPI44951.1 - 0.033 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B Pkinase PF00069.20 KPI44952.1 - 2.1e-60 204.1 0.0 3.6e-38 131.2 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KPI44952.1 - 6.9e-27 94.1 0.0 3.5e-21 75.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 KPI44952.1 - 1.8e-12 47.2 0.1 3.9e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 KPI44952.1 - 2.2e-08 33.4 0.0 6.9e-06 25.2 0.0 2.7 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KPI44952.1 - 1.8e-06 27.8 0.0 0.0039 16.9 0.1 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KPI44952.1 - 0.086 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KPI44952.1 - 0.088 11.6 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Fasciclin PF02469.17 KPI44956.1 - 0.00089 19.2 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain DUF3580 PF12117.3 KPI44956.1 - 0.0098 15.8 0.2 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3580) p450 PF00067.17 KPI44958.1 - 3.7e-47 160.9 0.0 4.9e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 JAB PF01398.16 KPI44958.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HET PF06985.6 KPI44959.1 - 1.8e-19 70.3 9.7 1.4e-17 64.1 0.3 2.9 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) tRNA-synt_1 PF00133.17 KPI44960.1 - 7.4e-213 707.8 4.1 4.2e-212 705.3 2.9 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KPI44960.1 - 7.7e-37 126.3 0.1 7.7e-37 126.3 0.0 2.8 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KPI44960.1 - 6.7e-16 57.9 2.3 4.3e-06 25.6 0.1 5.0 2 2 1 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KPI44960.1 - 1.2e-08 34.5 9.6 7.6e-08 31.8 0.0 3.8 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KPI44960.1 - 0.0086 15.2 0.0 0.13 11.3 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain PepSY PF03413.14 KPI44960.1 - 0.024 15.2 1.8 0.054 14.1 0.0 2.6 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain IncA PF04156.9 KPI44960.1 - 2.9 7.4 7.8 0.081 12.5 0.6 1.8 2 0 0 2 2 2 0 IncA protein Ribosomal_L37 PF08561.5 KPI44961.1 - 2e-23 81.7 2.1 8.4e-23 79.7 1.5 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 Acyl_transf_3 PF01757.17 KPI44962.1 - 1.4e-23 83.2 20.5 1.8e-23 82.9 14.2 1.2 1 0 0 1 1 1 1 Acyltransferase family ASFV_J13L PF05568.6 KPI44963.1 - 0.02 14.4 0.1 0.026 14.0 0.0 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein zf-GRF PF06839.7 KPI44964.1 - 8.7e-09 35.1 8.1 1.4e-08 34.4 5.6 1.3 1 0 0 1 1 1 1 GRF zinc finger bZIP_1 PF00170.16 KPI44964.1 - 0.065 13.1 0.3 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor RNA_pol_Rpb6 PF01192.17 KPI44965.1 - 1.1e-23 82.6 0.1 1.9e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 Nop14 PF04147.7 KPI44965.1 - 0.059 11.2 4.5 0.056 11.3 3.1 1.0 1 0 0 1 1 1 0 Nop14-like family IFT57 PF10498.4 KPI44965.1 - 0.47 9.1 3.1 0.52 9.0 2.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2890 PF11081.3 KPI44965.1 - 2.6 8.0 5.5 3.4 7.6 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 KPI44965.1 - 4.2 5.7 9.3 4.6 5.6 6.5 1.0 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 KPI44965.1 - 8.3 5.0 9.6 9.8 4.7 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CBM_4_9 PF02018.12 KPI44966.1 - 0.00012 22.1 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain PAN_4 PF14295.1 KPI44966.1 - 0.0057 16.3 2.3 0.0057 16.3 1.6 1.9 2 0 0 2 2 2 1 PAN domain PLA2_B PF01735.13 KPI44967.1 - 2.9e-69 233.5 0.0 3.9e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Abhydrolase_6 PF12697.2 KPI44968.1 - 1.3e-18 67.7 0.4 1.7e-18 67.3 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI44968.1 - 4.3e-12 46.0 0.0 1.5e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KPI44968.1 - 2.3e-06 27.4 0.0 4.8e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KPI44968.1 - 0.026 13.9 0.0 0.056 12.8 0.0 1.7 1 1 0 1 1 1 0 Putative esterase Ndr PF03096.9 KPI44968.1 - 0.057 11.8 0.0 0.083 11.3 0.0 1.1 1 0 0 1 1 1 0 Ndr family Phosducin PF02114.11 KPI44969.1 - 7.8e-10 37.9 0.0 9.7e-10 37.6 0.0 1.1 1 0 0 1 1 1 1 Phosducin Glycophorin_A PF01102.13 KPI44970.1 - 0.0053 16.5 1.1 0.011 15.4 0.7 1.7 1 1 0 1 1 1 1 Glycophorin A RNA_pol_Rpb2_2 PF04561.9 KPI44970.1 - 0.0093 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 Ctr PF04145.10 KPI44970.1 - 0.033 14.2 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Ctr copper transporter family OAD_gamma PF04277.8 KPI44970.1 - 0.033 14.5 0.0 0.082 13.2 0.0 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain FAM176 PF14851.1 KPI44970.1 - 0.043 13.5 0.2 0.069 12.8 0.1 1.3 1 0 0 1 1 1 0 FAM176 family Herpes_gE PF02480.11 KPI44970.1 - 0.044 12.0 0.0 0.059 11.6 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 KPI44970.1 - 0.12 11.2 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF2215 PF10225.4 KPI44970.1 - 0.15 11.4 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) FAM163 PF15069.1 KPI44970.1 - 2.7 8.5 6.1 0.65 10.5 0.2 2.1 1 1 1 2 2 2 0 FAM163 family RAP1 PF07218.6 KPI44970.1 - 4.6 5.2 4.8 7.6 4.4 3.3 1.3 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MFS_1 PF07690.11 KPI44971.1 - 2.9e-26 92.0 79.7 5.7e-22 77.9 28.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI44971.1 - 0.00025 19.5 31.0 0.027 12.8 13.1 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein G-gamma PF00631.17 KPI44972.1 - 7.2e-23 80.1 0.1 8.3e-23 79.9 0.0 1.1 1 0 0 1 1 1 1 GGL domain RSS_P20 PF11757.3 KPI44972.1 - 0.089 12.9 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like OPA3 PF07047.7 KPI44973.1 - 1.1e-33 115.8 0.2 2.9e-33 114.4 0.2 1.7 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF3844 PF12955.2 KPI44974.1 - 7.1e-34 116.0 3.6 1.1e-33 115.3 2.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 KPI44974.1 - 1.4 9.1 14.7 0.19 11.9 7.1 1.9 2 0 0 2 2 2 0 EGF-like domain Lipase_3 PF01764.20 KPI44975.1 - 8e-13 48.2 0.1 9.5e-12 44.7 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KPI44975.1 - 0.0047 16.6 0.1 0.0083 15.8 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family GHMP_kinases_C PF08544.8 KPI44975.1 - 0.018 15.1 0.2 0.062 13.5 0.1 1.9 1 0 0 1 1 1 0 GHMP kinases C terminal Abhydrolase_6 PF12697.2 KPI44975.1 - 0.023 14.5 2.5 0.06 13.2 1.8 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2048 PF09752.4 KPI44975.1 - 0.033 13.0 0.4 0.057 12.2 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Cutinase PF01083.17 KPI44975.1 - 0.093 12.4 0.1 0.2 11.3 0.0 1.5 2 0 0 2 2 2 0 Cutinase PGAP1 PF07819.8 KPI44975.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.15 KPI44975.1 - 0.14 11.5 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Putative esterase UPF0227 PF05728.7 KPI44975.1 - 0.16 11.6 0.1 0.45 10.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF4514 PF14986.1 KPI44975.1 - 0.22 11.3 1.2 0.41 10.4 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) Exo_endo_phos PF03372.18 KPI44976.1 - 1e-06 28.8 0.1 1.3e-06 28.5 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UQ_con PF00179.21 KPI44977.1 - 4.7e-51 171.8 0.0 5.3e-51 171.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KPI44977.1 - 7.3e-05 22.5 0.0 8.7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KPI44977.1 - 0.0054 16.6 0.0 0.0059 16.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KPI44977.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Pox_A14 PF05767.7 KPI44978.1 - 0.34 10.8 1.4 0.76 9.7 0.9 1.5 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Polysacc_synt_C PF14667.1 KPI44978.1 - 1.4 8.7 13.4 0.05 13.4 4.7 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Glyco_transf_25 PF01755.12 KPI44979.1 - 2.1e-13 50.3 0.2 5.6e-12 45.7 0.1 2.5 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DivIC PF04977.10 KPI44979.1 - 9.7 5.7 9.5 11 5.6 5.6 1.7 1 1 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.16 KPI44980.1 - 2.1e-07 30.7 9.7 5.9e-07 29.3 6.7 1.8 1 1 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.5 KPI44980.1 - 1.6e-05 24.8 0.0 1.6e-05 24.8 0.0 2.4 2 1 1 3 3 3 1 Transcription factor PAP1 TMF_TATA_bd PF12325.3 KPI44980.1 - 0.00088 19.0 2.5 0.0015 18.2 1.7 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding bZIP_Maf PF03131.12 KPI44980.1 - 0.0042 17.3 8.1 0.0042 17.3 5.6 1.5 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.10 KPI44980.1 - 0.02 14.7 12.6 0.03 14.1 8.1 1.7 1 1 1 2 2 2 0 Basic region leucine zipper HOOK PF05622.7 KPI44980.1 - 0.023 12.5 0.8 0.032 12.0 0.5 1.1 1 0 0 1 1 1 0 HOOK protein V_ATPase_I PF01496.14 KPI44980.1 - 0.028 12.2 0.1 0.034 12.0 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.9 KPI44980.1 - 0.045 13.3 2.7 0.084 12.4 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.3 KPI44980.1 - 0.09 12.6 6.9 0.23 11.3 4.8 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KPI44980.1 - 1.9 8.0 5.7 0.23 11.0 1.1 1.5 2 0 0 2 2 2 0 IncA protein Amidohydro_1 PF01979.15 KPI44982.1 - 5.2e-25 88.8 0.1 1.2e-15 57.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KPI44982.1 - 3e-13 49.3 0.1 1.3e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 KPI44982.1 - 3.7e-09 37.0 0.3 0.0002 21.4 0.0 3.2 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KPI44982.1 - 2.6e-07 30.1 0.1 1.1e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Mito_carr PF00153.22 KPI44983.1 - 9.4e-72 236.8 0.2 2.2e-24 84.9 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 KPI44983.1 - 2.3e-11 42.5 4.3 1.3e-05 24.7 0.0 5.6 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.27 KPI44983.1 - 6.4e-11 40.7 2.9 5.8e-06 25.2 0.0 5.0 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 KPI44983.1 - 2.5e-10 40.3 2.8 9.3e-05 22.4 0.3 4.5 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.1 KPI44983.1 - 5.7e-06 25.8 0.5 3.2 7.4 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KPI44983.1 - 2.2e-05 23.5 1.2 0.0086 15.3 0.0 4.2 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.1 KPI44983.1 - 0.012 15.4 0.1 7 6.6 0.0 3.4 3 0 0 3 3 3 0 EF-hand domain EF-hand_like PF09279.6 KPI44983.1 - 0.055 13.4 0.0 5.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like zf-RING_2 PF13639.1 KPI44984.1 - 2.3e-08 33.7 8.8 4.2e-08 32.9 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KPI44984.1 - 4.2e-05 23.1 4.9 7.1e-05 22.4 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI44984.1 - 0.00014 21.4 5.5 0.00023 20.8 3.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KPI44984.1 - 0.0008 19.3 10.0 0.0015 18.5 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI44984.1 - 0.011 15.3 7.5 0.02 14.5 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 KPI44984.1 - 0.063 13.0 8.4 0.18 11.5 5.8 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-HYPF PF07503.7 KPI44984.1 - 0.14 11.5 1.0 0.32 10.4 0.1 2.0 2 0 0 2 2 2 0 HypF finger zf-rbx1 PF12678.2 KPI44984.1 - 0.4 10.8 10.0 1 9.5 7.0 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KPI44984.1 - 1.2 8.9 5.4 2.3 8.0 3.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger SH3_1 PF00018.23 KPI44986.1 - 3e-35 119.3 9.4 1.1e-11 43.9 0.6 4.3 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 KPI44986.1 - 5.2e-35 118.9 0.1 1.1e-34 117.8 0.1 1.6 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 KPI44986.1 - 1.6e-29 101.2 6.1 4.5e-11 42.1 0.2 3.8 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 KPI44986.1 - 6.9e-20 70.2 0.0 4.5e-07 29.2 0.0 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 KPI44986.1 - 0.00016 21.7 2.8 0.9 9.7 0.2 3.6 3 0 0 3 3 3 2 Bacterial SH3 domain DUF1720 PF08226.6 KPI44986.1 - 0.0014 18.6 41.8 0.0014 18.6 29.0 6.5 1 1 4 5 5 5 2 Domain of unknown function (DUF1720) PA_decarbox PF05870.6 KPI44987.1 - 9.2e-08 31.7 0.1 1.3e-07 31.1 0.1 1.4 1 1 0 1 1 1 1 Phenolic acid decarboxylase (PAD) MMR_HSR1 PF01926.18 KPI44988.1 - 0.0011 18.9 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KPI44988.1 - 0.0016 17.6 0.0 0.0032 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KPI44988.1 - 0.021 14.7 0.5 0.11 12.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KPI44988.1 - 0.07 13.4 0.2 1.2 9.4 0.0 2.5 3 0 0 3 3 3 0 ABC transporter AAA_29 PF13555.1 KPI44988.1 - 0.082 12.4 0.0 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4047 PF13256.1 KPI44988.1 - 0.24 11.3 3.5 0.39 10.6 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) IncA PF04156.9 KPI44988.1 - 7.9 6.0 11.1 13 5.3 7.7 1.3 1 0 0 1 1 1 0 IncA protein Sugar_tr PF00083.19 KPI44989.1 - 6.1e-41 140.4 17.1 5.5e-27 94.4 4.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI44989.1 - 4.8e-25 88.0 29.0 1.6e-22 79.7 6.9 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI44989.1 - 5.1e-08 31.7 13.6 9.4e-05 20.9 3.6 3.2 3 0 0 3 3 3 3 MFS/sugar transport protein TBCA PF02970.11 KPI44990.1 - 8.7e-21 73.8 11.2 1.1e-20 73.4 7.5 1.4 1 1 0 1 1 1 1 Tubulin binding cofactor A DUF2570 PF10828.3 KPI44990.1 - 0.071 12.7 4.3 0.19 11.3 2.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Ribosomal_L17 PF01196.14 KPI44990.1 - 0.079 13.5 1.5 0.4 11.2 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L17 Flagellin_N PF00669.15 KPI44990.1 - 0.11 12.3 2.9 0.14 11.9 1.6 1.5 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region IncA PF04156.9 KPI44990.1 - 0.21 11.1 9.8 0.28 10.7 6.8 1.2 1 0 0 1 1 1 0 IncA protein DUF4609 PF15382.1 KPI44990.1 - 0.23 11.1 1.2 0.37 10.5 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) Syntaxin_2 PF14523.1 KPI44990.1 - 0.5 10.4 7.3 0.18 11.8 1.6 2.1 2 0 0 2 2 2 0 Syntaxin-like protein Med9 PF07544.8 KPI44990.1 - 1.2 8.8 9.9 0.58 9.9 3.3 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF2203 PF09969.4 KPI44990.1 - 1.6 9.0 6.0 1.6 8.9 0.9 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) FlxA PF14282.1 KPI44990.1 - 1.6 8.6 8.9 0.23 11.4 1.5 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF4407 PF14362.1 KPI44990.1 - 3.3 6.5 8.7 4 6.3 6.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FliJ PF02050.11 KPI44990.1 - 3.7 7.6 12.3 6.1 6.9 8.5 1.4 1 1 0 1 1 1 0 Flagellar FliJ protein Spectrin PF00435.16 KPI44990.1 - 4 7.7 9.1 3.7 7.9 1.8 2.0 1 1 1 2 2 2 0 Spectrin repeat DivIVA PF05103.8 KPI44990.1 - 4.7 7.2 12.2 6.7 6.7 8.4 1.2 1 0 0 1 1 1 0 DivIVA protein Abhydrolase_3 PF07859.8 KPI44991.1 - 6.2e-23 81.4 0.0 9.1e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KPI44991.1 - 0.15 12.2 0.1 0.72 10.0 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain ERG4_ERG24 PF01222.12 KPI44993.1 - 4.1e-82 276.0 14.6 4.8e-82 275.8 10.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Myb_DNA-binding PF00249.26 KPI44994.1 - 8.7e-09 35.3 0.6 7.6e-08 32.2 0.0 2.5 2 1 1 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KPI44994.1 - 1.4e-08 34.6 1.7 4e-08 33.2 0.2 2.2 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KPI44994.1 - 0.1 12.7 6.7 0.97 9.6 1.2 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Coiled-coil_56 PF09813.4 KPI44995.1 - 3.2e-05 23.8 0.0 3.6e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 ATP-synt PF00231.14 KPI44996.1 - 3.2e-69 233.4 0.4 4.3e-69 233.0 0.3 1.2 1 0 0 1 1 1 1 ATP synthase TPP_enzyme_N PF02776.13 KPI44997.1 - 1.6e-38 131.8 0.1 2.2e-37 128.1 0.0 2.7 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KPI44997.1 - 6.7e-33 113.3 0.1 1.4e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KPI44997.1 - 1.8e-19 69.8 0.1 7.7e-19 67.7 0.1 2.0 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Thiolase_N PF00108.18 KPI44998.1 - 1.2e-98 329.3 0.7 1.6e-98 328.9 0.0 1.6 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KPI44998.1 - 2.5e-46 156.1 1.3 5.7e-46 154.9 0.9 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KPI44998.1 - 4.8e-05 22.9 1.0 4.8e-05 22.9 0.7 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KPI44998.1 - 0.0092 15.6 1.5 0.41 10.3 0.1 2.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.17 KPI44998.1 - 0.03 14.1 0.5 2 8.2 0.6 3.1 2 1 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain PHD PF00628.24 KPI44999.1 - 0.019 14.6 2.3 0.069 12.8 1.6 1.9 1 1 0 1 1 1 0 PHD-finger zf-CSL PF05207.8 KPI45000.1 - 2.7e-22 78.0 0.5 3.8e-22 77.5 0.3 1.2 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 KPI45000.1 - 0.0051 16.7 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Zinc ribbon domain Terminase_GpA PF05876.7 KPI45000.1 - 0.037 12.3 0.1 0.039 12.3 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DUF1675 PF07897.6 KPI45001.1 - 1.4 8.7 9.0 1.6 8.5 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Mob1_phocein PF03637.12 KPI45002.1 - 1.1e-70 236.8 0.0 1.5e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family eIF-3_zeta PF05091.7 KPI45003.1 - 3.2e-173 577.0 5.8 4e-138 461.2 0.5 2.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) WD40 PF00400.27 KPI45004.1 - 7.9e-67 218.9 20.8 1.1e-09 37.8 0.1 11.6 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.7 KPI45004.1 - 2.4e-18 66.0 0.1 4e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 KPI45004.1 - 4e-07 28.5 1.5 0.017 13.2 0.0 4.3 3 1 0 4 4 4 3 Nucleoporin Nup120/160 PAN_4 PF14295.1 KPI45005.1 - 3.5e-07 29.8 1.3 6.5e-07 28.9 0.9 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 KPI45005.1 - 1.5e-05 24.6 0.0 3.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 KPI45005.1 - 0.0011 18.5 0.5 0.0021 17.6 0.3 1.5 1 0 0 1 1 1 1 PAN-like domain TAFII55_N PF04658.8 KPI45006.1 - 2.6e-44 150.5 0.5 7.5e-44 149.0 0.0 2.1 2 0 0 2 2 2 1 TAFII55 protein conserved region Atg14 PF10186.4 KPI45006.1 - 0.12 11.3 2.5 0.25 10.2 1.8 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 KPI45006.1 - 1.4 8.7 4.1 4 7.2 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FSH1 PF03959.8 KPI45007.1 - 2.5e-20 72.8 0.0 1.9e-12 47.1 0.0 2.0 1 1 1 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KPI45007.1 - 0.019 14.3 0.1 0.25 10.7 0.1 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KPI45007.1 - 0.031 14.1 0.1 0.038 13.8 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Vps55 PF04133.9 KPI45007.1 - 0.042 13.5 0.5 2.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting 55 UPF0261 PF06792.6 KPI45008.1 - 2.2e-101 339.2 0.2 2.6e-101 339.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Cation_efflux PF01545.16 KPI45009.1 - 3.7e-57 193.5 0.3 5e-57 193.1 0.2 1.1 1 0 0 1 1 1 1 Cation efflux family TrkH PF02386.11 KPI45009.1 - 0.018 13.6 0.1 0.027 13.0 0.1 1.2 1 0 0 1 1 1 0 Cation transport protein Helicase_C PF00271.26 KPI45011.1 - 2.2e-14 53.0 0.0 5e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain B3_4 PF03483.12 KPI45012.1 - 5.3e-17 61.8 0.0 7e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 B3/4 domain ADH_zinc_N PF00107.21 KPI45014.1 - 8e-09 35.1 0.0 1.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI45014.1 - 2.1e-06 27.4 0.0 1.1e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ImmE5 PF11480.3 KPI45014.1 - 0.0095 15.7 0.0 0.029 14.1 0.0 1.8 2 0 0 2 2 2 1 Colicin-E5 Imm protein Acyl-CoA_dh_1 PF00441.19 KPI45015.1 - 2.8e-28 98.8 0.1 4e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KPI45015.1 - 2.2e-20 71.9 0.1 4e-20 71.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KPI45015.1 - 2.6e-16 60.2 0.5 2.2e-14 53.9 0.0 2.8 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KPI45015.1 - 0.023 14.9 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans_2 PF11951.3 KPI45016.1 - 0.00095 17.8 0.0 0.011 14.3 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain PGA2 PF07543.7 KPI45017.1 - 6.1e-08 32.5 0.2 7.6e-08 32.2 0.1 1.3 1 1 0 1 1 1 1 Protein trafficking PGA2 Ank_2 PF12796.2 KPI45018.1 - 3.5e-12 46.4 0.1 9.6e-12 45.0 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KPI45018.1 - 1.2e-11 44.4 0.3 4e-09 36.4 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KPI45018.1 - 2.7e-10 40.4 1.2 5.4e-06 26.7 0.1 2.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 KPI45018.1 - 1.5e-08 34.0 3.8 6.5e-06 25.7 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 KPI45018.1 - 1.8e-07 30.6 1.3 0.00041 20.3 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat BAH PF01426.13 KPI45019.1 - 0.0013 18.4 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 BAH domain MazG-like PF12643.2 KPI45020.1 - 0.13 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 MazG-like family Aminotran_1_2 PF00155.16 KPI45022.1 - 4.3e-15 55.5 0.0 6.3e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KPI45022.1 - 0.0082 14.7 0.0 0.017 13.7 0.0 1.4 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase ATP-synt_ab PF00006.20 KPI45025.1 - 1.3e-71 240.4 0.0 2.5e-71 239.5 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KPI45025.1 - 1.5e-28 99.5 0.6 8.5e-28 97.1 0.4 2.2 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KPI45025.1 - 9e-17 61.0 3.0 2.3e-16 59.7 2.1 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KPI45025.1 - 0.036 13.9 1.7 0.18 11.6 1.2 2.2 1 1 0 1 1 1 0 HAS barrel domain Tex_N PF09371.5 KPI45025.1 - 0.082 12.2 0.1 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Tex-like protein N-terminal domain AAA_25 PF13481.1 KPI45025.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KPI45026.1 - 5e-50 169.1 0.0 8.8e-44 148.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KPI45026.1 - 8.7e-05 22.5 0.0 0.007 16.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KPI45026.1 - 0.00029 19.9 0.0 0.00066 18.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KPI45026.1 - 0.00032 20.1 0.0 0.0019 17.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KPI45026.1 - 0.00053 20.7 0.0 0.0015 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KPI45026.1 - 0.00075 19.5 0.9 0.022 14.7 0.0 3.1 2 1 1 3 3 2 1 AAA ATPase domain IstB_IS21 PF01695.12 KPI45026.1 - 0.00093 18.6 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Parvo_NS1 PF01057.12 KPI45026.1 - 0.0015 17.4 0.0 0.0028 16.5 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 KPI45026.1 - 0.0017 18.5 0.0 0.0099 16.0 0.0 2.3 2 1 1 3 3 2 1 AAA domain AAA_19 PF13245.1 KPI45026.1 - 0.003 17.2 0.1 0.027 14.1 0.0 2.7 2 1 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 KPI45026.1 - 0.0044 17.1 0.0 0.015 15.4 0.0 2.0 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 KPI45026.1 - 0.0062 15.3 0.0 0.012 14.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_3 PF07726.6 KPI45026.1 - 0.017 14.6 0.0 1.7 8.2 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KPI45026.1 - 0.02 14.6 0.0 0.07 12.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KPI45026.1 - 0.024 13.8 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KPI45026.1 - 0.036 13.1 0.0 0.088 11.9 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 KPI45026.1 - 0.047 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KPI45026.1 - 0.084 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 KPI45026.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 KPI45026.1 - 0.48 8.9 0.0 0.76 8.3 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Methyltransf_23 PF13489.1 KPI45027.1 - 8.4e-24 84.1 0.0 1.2e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI45027.1 - 1.5e-16 60.6 0.0 2.2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI45027.1 - 5.7e-16 58.8 0.0 7.8e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI45027.1 - 3.2e-13 50.2 0.0 4.7e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI45027.1 - 1.3e-12 47.5 0.0 1.7e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI45027.1 - 6.1e-10 39.3 0.0 9.3e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI45027.1 - 1.6e-07 31.3 0.1 1e-06 28.7 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KPI45027.1 - 5.1e-06 25.9 0.0 4.8e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KPI45027.1 - 1.5e-05 24.2 0.0 1.9e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 KPI45027.1 - 0.00086 18.7 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 KPI45027.1 - 0.00087 18.0 0.0 0.0012 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 KPI45027.1 - 0.0015 17.6 0.0 0.0019 17.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KPI45027.1 - 0.043 12.8 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_PK PF05891.7 KPI45027.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DUF2235 PF09994.4 KPI45028.1 - 2.4e-64 217.3 0.0 3.4e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KPI45028.1 - 0.091 12.5 0.0 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family YabP PF07873.6 KPI45029.1 - 0.012 15.1 0.0 0.038 13.5 0.0 1.9 2 0 0 2 2 2 0 YabP family Herpes_LMP1 PF05297.6 KPI45029.1 - 3.3 6.5 7.9 2.3 7.0 3.6 2.0 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Pkinase PF00069.20 KPI45030.1 - 5.3e-42 143.7 0.0 1.2e-41 142.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI45030.1 - 2.3e-23 82.5 0.0 4.2e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI45030.1 - 0.28 10.1 0.0 0.5 9.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Vps53_N PF04100.7 KPI45031.1 - 2.3e-86 289.9 0.0 4.7e-86 288.9 0.0 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.8 KPI45031.1 - 3.2e-08 32.1 0.0 4.6e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 DUF2450 PF10475.4 KPI45031.1 - 1.3e-07 30.8 0.4 2.7e-07 29.7 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 KPI45031.1 - 0.0094 15.8 0.3 0.057 13.2 0.0 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Flagellin_C PF00700.16 KPI45031.1 - 0.02 15.0 4.7 0.036 14.2 2.1 2.3 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region DUF2451 PF10474.4 KPI45031.1 - 0.085 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Beta_elim_lyase PF01212.16 KPI45032.1 - 1.3e-51 175.5 0.0 1.6e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KPI45032.1 - 0.0012 17.2 0.0 0.0016 16.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 KPI45032.1 - 0.0022 16.6 0.0 0.0026 16.3 0.0 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.12 KPI45032.1 - 0.009 15.0 0.0 0.023 13.7 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 KPI45032.1 - 0.072 11.5 0.0 0.079 11.3 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain FGGY_C PF02782.11 KPI45033.1 - 2.7e-20 72.8 0.0 4.1e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KPI45033.1 - 8.2e-18 64.6 0.0 3e-11 43.1 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Alg6_Alg8 PF03155.10 KPI45035.1 - 8.6e-132 440.2 18.5 1.4e-81 274.7 4.4 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Metallophos PF00149.23 KPI45036.1 - 5.1e-38 130.4 0.0 6e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Fungal_trans PF04082.13 KPI45037.1 - 5.7e-10 38.5 0.0 8.6e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Asp PF00026.18 KPI45038.1 - 2.9e-58 197.5 4.6 2.9e-58 197.5 3.2 2.7 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KPI45038.1 - 0.077 12.5 0.0 0.077 12.5 0.0 2.6 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal RPN7 PF10602.4 KPI45039.1 - 4.2e-42 143.5 0.1 7.7e-42 142.6 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KPI45039.1 - 1.7e-12 47.5 0.2 7.3e-12 45.5 0.1 2.1 1 1 0 1 1 1 1 PCI domain TPT PF03151.11 KPI45040.1 - 0.027 14.1 0.4 0.088 12.4 0.3 1.9 1 0 0 1 1 1 0 Triose-phosphate Transporter family MFS_1 PF07690.11 KPI45040.1 - 2.3 6.8 11.0 0.078 11.6 3.3 1.8 2 0 0 2 2 2 0 Major Facilitator Superfamily Methyltransf_16 PF10294.4 KPI45041.1 - 0.00042 19.8 0.0 0.28 10.6 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase CorA PF01544.13 KPI45042.1 - 1.2e-11 44.1 0.1 1.9e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4455 PF14643.1 KPI45042.1 - 0.035 12.7 1.8 0.046 12.3 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Pox_P35 PF03213.9 KPI45042.1 - 1.2 8.0 3.3 2.5 7.0 2.3 1.7 1 1 0 1 1 1 0 Poxvirus P35 protein FAD_binding_4 PF01565.18 KPI45043.1 - 6.1e-20 71.1 0.2 1e-19 70.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KPI45043.1 - 0.00034 20.4 0.1 0.0009 19.0 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like E1-E2_ATPase PF00122.15 KPI45046.1 - 2.2e-66 223.1 1.3 2.2e-66 223.1 0.9 2.7 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KPI45046.1 - 5.6e-23 82.4 0.0 1.7e-22 80.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KPI45046.1 - 2.7e-13 50.5 0.0 6.4e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KPI45046.1 - 8.3e-11 41.2 0.0 1.9e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KPI45046.1 - 0.00027 20.8 0.0 0.00058 19.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KPI45046.1 - 0.0015 18.1 0.1 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase BNR PF02012.15 KPI45047.1 - 2.8e-06 26.3 43.6 1.5 8.9 0.5 11.7 11 0 0 11 11 11 6 BNR/Asp-box repeat CHB_HEX_C_1 PF13290.1 KPI45047.1 - 0.0014 18.3 0.1 6.9 6.5 0.0 4.5 5 0 0 5 5 5 1 Chitobiase/beta-hexosaminidase C-terminal domain DUF2167 PF09935.4 KPI45047.1 - 0.15 10.8 0.8 36 3.0 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2167) CBS PF00571.23 KPI45049.1 - 2e-07 30.6 0.0 0.061 13.1 0.0 3.1 2 1 1 3 3 3 2 CBS domain Remorin_N PF03766.8 KPI45049.1 - 0.059 13.1 0.5 0.13 12.1 0.4 1.5 1 0 0 1 1 1 0 Remorin, N-terminal region adh_short_C2 PF13561.1 KPI45050.1 - 4.7e-30 105.1 0.0 6.5e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI45050.1 - 1.2e-28 100.1 0.2 1.5e-28 99.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI45050.1 - 9.4e-08 31.9 0.1 2.1e-07 30.8 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI45050.1 - 0.00013 21.5 0.3 0.00021 20.7 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI45050.1 - 0.001 19.1 0.2 0.0014 18.6 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KPI45050.1 - 0.029 14.3 0.2 0.054 13.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_3 PF03447.11 KPI45050.1 - 0.09 13.1 0.1 0.51 10.7 0.1 2.1 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KPI45050.1 - 0.14 10.9 1.4 0.49 9.2 0.1 2.0 1 1 0 2 2 2 0 Polysaccharide biosynthesis protein Sel1 PF08238.7 KPI45051.1 - 6.5e-37 125.1 23.9 1.6e-06 28.5 0.1 7.5 7 0 0 7 7 7 7 Sel1 repeat ATP-synt_DE_N PF02823.11 KPI45053.1 - 1.5e-19 69.5 0.1 2.2e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain OMPdecase PF00215.19 KPI45054.1 - 3.4e-72 242.5 0.4 3.9e-72 242.3 0.3 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family POLO_box PF00659.13 KPI45055.1 - 0.00046 20.0 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 POLO box duplicated region MFS_1 PF07690.11 KPI45056.1 - 6.9e-32 110.5 39.3 2.1e-31 108.9 27.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KPI45056.1 - 2.7e-05 22.5 18.8 4.3e-05 21.9 13.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1118 PF06549.7 KPI45056.1 - 0.019 15.1 0.5 0.079 13.1 0.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) Fungal_trans PF04082.13 KPI45058.1 - 6.2e-27 94.1 0.1 1e-26 93.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain BTB PF00651.26 KPI45059.1 - 0.00018 21.4 0.0 0.0012 18.7 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain DUF3597 PF12200.3 KPI45060.1 - 0.026 14.9 1.5 0.026 14.9 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) DUF4366 PF14283.1 KPI45060.1 - 0.09 12.1 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RGS PF00615.14 KPI45061.1 - 2.8e-05 24.1 0.1 0.06 13.4 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain Ribosomal_L15e PF00827.12 KPI45062.1 - 5.7e-91 303.2 13.1 6.5e-91 303.0 9.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 Codanin-1_C PF15296.1 KPI45062.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Codanin-1 C-terminus CH PF00307.26 KPI45063.1 - 1.2e-11 44.6 0.0 2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Ribonuc_L-PSP PF01042.16 KPI45066.1 - 3.7e-31 107.4 0.0 4.7e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP LRR_4 PF12799.2 KPI45067.1 - 6.1e-17 60.8 10.0 1.4e-08 34.1 0.1 3.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) Exo_endo_phos PF03372.18 KPI45067.1 - 1.5e-16 61.1 0.2 2.1e-16 60.6 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.1 KPI45067.1 - 4.3e-08 32.7 1.3 1.1e-07 31.4 0.5 2.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 KPI45067.1 - 1.2e-05 24.7 4.0 0.097 12.7 0.0 4.9 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 KPI45067.1 - 0.0013 18.6 4.9 0.34 11.3 0.0 4.5 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 KPI45067.1 - 0.53 10.5 6.4 3.1 8.1 0.0 4.1 5 0 0 5 5 5 0 Leucine Rich repeat Fungal_trans_2 PF11951.3 KPI45068.1 - 9.9e-50 169.2 0.2 1.5e-49 168.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI45068.1 - 4.2e-06 26.5 11.8 7.1e-06 25.8 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MS_channel PF00924.13 KPI45069.1 - 1.2e-24 86.8 1.4 1.9e-24 86.1 1.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KPI45069.1 - 0.00034 19.6 0.2 0.00082 18.5 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 KPI45069.1 - 0.00052 19.2 0.0 0.0013 18.0 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KPI45069.1 - 0.0008 19.4 0.4 0.0021 18.1 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KPI45069.1 - 0.0014 18.3 0.0 0.005 16.6 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain Adeno_E4_ORF3 PF06931.6 KPI45069.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Mastadenovirus E4 ORF3 protein Sugar_tr PF00083.19 KPI45071.1 - 4e-52 177.3 21.0 4.6e-52 177.0 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI45071.1 - 1.4e-22 79.9 32.3 1.6e-22 79.7 20.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KPI45071.1 - 9.1e-06 24.3 29.3 0.00063 18.2 7.3 4.0 2 2 2 4 4 4 2 MFS/sugar transport protein DUF872 PF05915.7 KPI45071.1 - 0.03 14.1 0.7 0.3 10.9 0.0 2.7 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) YIEGIA PF14045.1 KPI45071.1 - 0.099 11.2 3.3 0.038 12.6 0.3 1.8 2 0 0 2 2 2 0 YIEGIA protein Clostridium_P47 PF06597.6 KPI45071.1 - 0.2 10.1 0.2 0.36 9.3 0.1 1.3 1 0 0 1 1 1 0 Clostridium P-47 protein PepSY_TM_2 PF13703.1 KPI45071.1 - 1.9 8.7 18.3 1 9.6 0.2 4.3 2 1 1 3 3 3 0 PepSY-associated TM helix Endonuc_BglI PF14562.1 KPI45072.1 - 0.069 11.9 0.1 0.089 11.6 0.1 1.1 1 0 0 1 1 1 0 Restriction endonuclease BglI NIR_SIR PF01077.17 KPI45075.1 - 7.3e-29 100.1 0.0 1.2e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Fer2_BFD PF04324.10 KPI45075.1 - 1.7e-12 47.2 3.6 6.8e-10 38.8 2.8 2.5 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.21 KPI45075.1 - 1.4e-08 34.2 0.2 6.8e-08 31.9 0.0 2.3 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain Pyr_redox_2 PF07992.9 KPI45075.1 - 3.5e-08 33.5 0.1 7.7e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 KPI45075.1 - 1e-07 31.5 0.0 3.3e-06 26.7 0.0 3.3 3 1 0 3 3 3 1 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.12 KPI45075.1 - 6.8e-07 28.8 0.0 1.6e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pex19 PF04614.7 KPI45075.1 - 0.0021 17.7 0.1 0.36 10.3 0.0 2.2 2 0 0 2 2 2 2 Pex19 protein family DUF2457 PF10446.4 KPI45076.1 - 0.071 11.8 4.6 0.1 11.3 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PHD PF00628.24 KPI45076.1 - 0.29 10.8 6.1 0.61 9.8 4.2 1.6 1 0 0 1 1 1 0 PHD-finger ORC3_N PF07034.6 KPI45077.1 - 8.7e-15 54.5 2.8 3.1e-11 42.8 0.8 2.5 2 0 0 2 2 2 2 Origin recognition complex (ORC) subunit 3 N-terminus Amino_oxidase PF01593.19 KPI45078.1 - 1e-33 117.1 0.8 8.8e-33 114.0 0.5 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KPI45078.1 - 2.6e-12 46.5 0.3 1.1e-11 44.5 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KPI45078.1 - 2.6e-06 26.5 0.6 5.6e-06 25.5 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KPI45078.1 - 4.4e-06 25.4 0.1 3e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KPI45078.1 - 4.8e-06 25.6 0.4 7.6e-06 25.0 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KPI45078.1 - 1.7e-05 25.0 0.2 0.0027 17.7 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI45078.1 - 3.5e-05 22.9 0.1 5.7e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KPI45078.1 - 5.1e-05 23.2 0.1 8.2e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KPI45078.1 - 0.00039 19.6 0.7 0.00068 18.8 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KPI45078.1 - 0.00045 20.5 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI45078.1 - 0.00063 18.7 0.3 0.00094 18.1 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KPI45078.1 - 0.0024 16.8 0.2 0.0044 16.0 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 KPI45078.1 - 0.0026 16.8 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KPI45078.1 - 0.039 13.7 0.7 0.91 9.2 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Ank_2 PF12796.2 KPI45079.1 - 9.8e-39 131.5 0.0 8.4e-20 70.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) HET PF06985.6 KPI45079.1 - 1.6e-20 73.7 2.6 1.8e-19 70.2 0.3 2.7 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Ank PF00023.25 KPI45079.1 - 8.4e-20 69.5 0.0 2.7e-09 36.3 0.1 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KPI45079.1 - 2.2e-18 64.5 0.0 7.6e-07 28.7 0.1 5.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KPI45079.1 - 5.2e-17 61.8 0.1 2.9e-10 40.3 0.1 4.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KPI45079.1 - 1.5e-16 59.9 0.6 5e-07 29.7 0.1 4.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Clr5 PF14420.1 KPI45079.1 - 1.1e-14 53.9 1.8 3.2e-14 52.5 0.5 2.3 2 0 0 2 2 2 1 Clr5 domain NACHT PF05729.7 KPI45079.1 - 1.7e-06 27.7 0.0 1.2e-05 25.0 0.0 2.4 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 KPI45079.1 - 0.00052 20.1 0.1 0.034 14.2 0.0 3.4 2 1 1 3 3 3 1 AAA domain ResIII PF04851.10 KPI45079.1 - 0.066 13.0 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit APS_kinase PF01583.15 KPI45079.1 - 0.091 12.4 0.1 0.33 10.5 0.1 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase NTPase_1 PF03266.10 KPI45079.1 - 0.12 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 NTPase MFS_1 PF07690.11 KPI45080.1 - 1e-27 96.8 16.0 1e-27 96.8 11.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 KPI45081.1 - 3.6e-23 81.8 34.8 2.7e-12 46.1 6.7 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.3 KPI45081.1 - 6.3e-08 31.5 2.9 1.4e-05 23.8 0.8 2.3 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_2 PF13347.1 KPI45081.1 - 2.8e-06 25.9 18.9 0.00032 19.2 2.0 3.8 3 1 0 3 3 3 3 MFS/sugar transport protein AATase PF07247.7 KPI45082.1 - 1.3e-18 66.7 0.0 1.3e-13 50.3 0.0 2.2 1 1 1 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.15 KPI45082.1 - 0.015 14.1 0.1 0.032 13.0 0.0 1.5 2 0 0 2 2 2 0 Condensation domain adh_short PF00106.20 KPI45085.1 - 5.2e-14 52.5 0.0 6.8e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI45085.1 - 0.0033 17.1 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 KPI45085.1 - 0.029 13.9 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1471 PF07338.8 KPI45085.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) OSCP PF00213.13 KPI45086.1 - 1.6e-41 142.0 0.5 1.8e-41 141.8 0.4 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Ank PF00023.25 KPI45087.1 - 2.2e-39 131.3 1.1 9.1e-11 41.0 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 KPI45087.1 - 1.9e-35 121.0 0.0 1.2e-18 67.1 0.0 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KPI45087.1 - 1.9e-26 89.4 1.7 5.5e-08 32.3 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 KPI45087.1 - 2.8e-24 84.5 3.5 8.7e-08 32.1 0.0 4.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KPI45087.1 - 5.5e-24 84.0 0.7 2.7e-10 40.4 0.1 4.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DIOX_N PF14226.1 KPI45088.1 - 1.4e-15 57.8 0.0 3.4e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI45088.1 - 1.4e-10 41.2 0.0 4.1e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Peptidase_S8 PF00082.17 KPI45089.1 - 2.2e-50 171.4 0.6 3.4e-50 170.7 0.4 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KPI45089.1 - 1.4e-30 104.9 0.6 2.8e-30 103.9 0.4 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain SPC25 PF06703.6 KPI45090.1 - 3.5e-41 140.4 0.0 4.2e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Pkinase PF00069.20 KPI45091.1 - 1.4e-64 217.7 0.0 2e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI45091.1 - 2.9e-29 101.9 0.0 4.9e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KPI45091.1 - 1.3e-10 41.2 0.0 3.3e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KPI45091.1 - 6.1e-06 25.4 0.0 2.8e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KPI45091.1 - 0.004 16.9 0.1 0.049 13.3 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KPI45091.1 - 0.0082 15.2 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KPI45091.1 - 0.062 12.0 0.2 0.092 11.5 0.2 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase P34-Arc PF04045.9 KPI45092.1 - 7.8e-104 346.2 0.6 1.1e-103 345.7 0.4 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc GFO_IDH_MocA PF01408.17 KPI45092.1 - 4.3e-17 62.7 0.1 1.1e-16 61.4 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ARPC4 PF05856.7 KPI45092.1 - 0.011 15.1 0.1 0.038 13.3 0.1 1.9 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) 2OG-FeII_Oxy_2 PF13532.1 KPI45093.1 - 1e-27 97.2 0.0 1.7e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KPI45093.1 - 1.8e-05 24.9 0.0 4.4e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.2 KPI45095.1 - 9.3e-22 78.0 1.9 1.2e-21 77.7 1.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI45095.1 - 2.4e-12 46.8 0.1 3.5e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 KPI45095.1 - 0.00014 21.4 0.1 0.0093 15.4 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase ABC_sub_bind PF04392.7 KPI45095.1 - 0.009 15.0 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter substrate binding protein TrbH PF07283.6 KPI45095.1 - 0.1 12.4 0.0 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 Conjugal transfer protein TrbH Carb_kinase PF01256.12 KPI45096.1 - 8.7e-53 179.0 0.0 1.1e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KPI45096.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.4 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase FAD_binding_3 PF01494.14 KPI45097.1 - 1.5e-06 27.5 4.7 0.00084 18.4 0.1 2.7 2 1 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 KPI45097.1 - 0.00035 20.3 0.3 0.0014 18.4 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KPI45097.1 - 0.0034 17.3 1.6 0.0061 16.5 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI45097.1 - 0.014 15.3 0.7 0.031 14.1 0.5 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI45097.1 - 0.028 12.8 0.4 0.049 12.0 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 KPI45097.1 - 0.034 14.2 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KPI45097.1 - 0.065 12.0 0.0 0.46 9.2 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.17 KPI45097.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KPI45097.1 - 0.46 10.0 2.0 1.1 8.8 0.0 2.4 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain DNA_mis_repair PF01119.14 KPI45098.1 - 8.8e-14 50.9 0.0 1.8e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 KPI45098.1 - 4.4e-11 42.4 0.3 1.1e-10 41.1 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KPI45098.1 - 4e-10 39.4 0.6 9.7e-10 38.2 0.4 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SUI1 PF01253.17 KPI45099.1 - 2.6e-21 75.2 0.2 4.9e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 tRNA_edit PF04073.10 KPI45099.1 - 0.082 12.7 0.9 0.12 12.2 0.6 1.2 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain Amidohydro_1 PF01979.15 KPI45099.1 - 0.15 11.6 0.9 0.25 10.9 0.5 1.3 1 1 0 1 1 1 0 Amidohydrolase family FKBP_N PF01346.13 KPI45099.1 - 6.4 6.8 10.5 17 5.4 3.4 2.3 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase adh_short PF00106.20 KPI45100.1 - 6.9e-16 58.6 0.0 9.9e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI45100.1 - 1.2e-05 25.0 0.0 0.0024 17.5 0.0 2.1 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 KPI45100.1 - 8e-05 22.7 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Bromo_TP PF07524.8 KPI45101.1 - 1.5e-13 50.2 0.6 2.7e-13 49.4 0.1 1.6 2 0 0 2 2 2 1 Bromodomain associated TFIID-31kDa PF02291.10 KPI45101.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF3533 PF12051.3 KPI45102.1 - 7e-95 317.9 6.7 1.2e-94 317.1 4.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3533) DUF4234 PF14018.1 KPI45102.1 - 0.012 15.3 0.3 0.012 15.3 0.2 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4234) DUF641 PF04859.7 KPI45103.1 - 0.0051 16.5 18.4 0.057 13.1 1.6 2.4 2 0 0 2 2 2 2 Plant protein of unknown function (DUF641) Baculo_PEP_C PF04513.7 KPI45103.1 - 0.11 12.2 4.8 0.044 13.6 1.5 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Matrilin_ccoil PF10393.4 KPI45103.1 - 0.35 10.2 4.1 3.1 7.2 0.1 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin ADIP PF11559.3 KPI45103.1 - 1.5 8.7 38.9 0.071 13.0 7.5 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding GTPase_Cys_C PF12631.2 KPI45103.1 - 3.2 8.2 9.4 0.27 11.6 0.4 3.2 2 2 1 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Laminin_I PF06008.9 KPI45104.1 - 0.00014 21.2 1.4 0.00028 20.3 1.0 1.4 1 0 0 1 1 1 1 Laminin Domain I DUF3454 PF11936.3 KPI45104.1 - 2 8.6 10.7 0.53 10.5 0.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3454) Ada_Zn_binding PF02805.11 KPI45105.1 - 2e-24 84.9 6.4 3.5e-24 84.1 4.4 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 KPI45105.1 - 0.028 14.2 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family DUF3576 PF12100.3 KPI45105.1 - 0.076 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) TCR_zetazeta PF11628.3 KPI45105.1 - 0.21 11.0 0.2 0.38 10.2 0.2 1.3 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain CMD PF02627.15 KPI45107.1 - 4.9e-05 23.0 0.0 0.00039 20.1 0.0 2.3 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family p450 PF00067.17 KPI45108.1 - 4.3e-63 213.4 0.0 5.3e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF-6 PF01912.13 KPI45109.1 - 1.1e-80 269.4 0.2 1.4e-80 269.0 0.2 1.2 1 0 0 1 1 1 1 eIF-6 family Cache_1 PF02743.13 KPI45109.1 - 0.094 12.2 0.4 15 5.2 0.0 2.7 3 0 0 3 3 3 0 Cache domain Zip PF02535.17 KPI45110.1 - 3.4e-26 92.0 0.0 3.9e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Yippee-Mis18 PF03226.9 KPI45112.1 - 1.1e-05 25.3 1.1 0.00018 21.4 0.9 2.3 1 1 1 2 2 2 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly KIAA1430 PF13879.1 KPI45112.1 - 0.011 16.1 4.1 0.026 14.9 2.9 1.6 1 0 0 1 1 1 0 KIAA1430 homologue IncA PF04156.9 KPI45112.1 - 0.017 14.6 1.5 0.027 14.0 1.0 1.2 1 0 0 1 1 1 0 IncA protein CHASE3 PF05227.8 KPI45112.1 - 0.36 10.5 7.4 0.65 9.6 5.1 1.3 1 0 0 1 1 1 0 CHASE3 domain DUF972 PF06156.8 KPI45112.1 - 1.4 9.3 5.5 8.1 6.8 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) p450 PF00067.17 KPI45113.1 - 6.3e-50 170.0 0.0 8.8e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.17 KPI45114.1 - 1.4e-44 149.5 0.0 3.7e-22 77.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI45114.1 - 9.1e-33 112.0 0.0 1.1e-16 60.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI45114.1 - 1.1e-19 69.9 0.0 2.5e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 KPI45115.1 - 3.4e-34 118.1 25.0 4.9e-34 117.5 17.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2929 PF11151.3 KPI45115.1 - 0.63 10.1 0.0 0.63 10.1 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2929) Cys_Met_Meta_PP PF01053.15 KPI45116.1 - 8.6e-20 70.3 0.0 1.2e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KPI45116.1 - 2.3e-05 23.5 0.0 3.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Adeno_PX PF05829.7 KPI45116.1 - 0.37 10.3 4.8 0.7 9.4 3.3 1.4 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) HATPase_c_3 PF13589.1 KPI45118.1 - 0.18 11.4 5.3 2 8.0 1.6 2.4 1 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L19e PF01280.15 KPI45118.1 - 8.4 6.1 12.7 0.7 9.6 4.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L19e Methyltransf_2 PF00891.13 KPI45119.1 - 3.6e-41 140.9 0.0 6.2e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KPI45119.1 - 1.5e-05 25.5 0.0 7.4e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 KPI45119.1 - 0.019 14.2 0.0 0.081 12.1 0.0 1.9 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Imm31 PF15595.1 KPI45119.1 - 0.058 13.1 0.5 4.8 6.9 0.0 2.6 1 1 1 2 2 2 0 Immunity protein 31 HECT_2 PF09814.4 KPI45120.1 - 5.4e-47 160.2 0.2 3.1e-30 105.0 0.1 2.0 2 0 0 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding F-box-like PF12937.2 KPI45121.1 - 0.0018 17.9 0.0 0.0089 15.7 0.0 2.1 1 1 0 1 1 1 1 F-box-like Trns_repr_metal PF02583.12 KPI45122.1 - 0.082 13.1 5.9 13 6.0 0.0 3.1 2 1 1 3 3 3 0 Metal-sensitive transcriptional repressor Macoilin PF09726.4 KPI45122.1 - 0.38 8.9 7.2 0.44 8.7 5.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Fmp27_WPPW PF10359.4 KPI45122.1 - 0.66 8.3 5.0 0.81 8.0 3.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Atg14 PF10186.4 KPI45122.1 - 1.1 8.0 8.8 1.7 7.5 6.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3340 PF11818.3 KPI45122.1 - 4.7 7.1 11.2 24 4.8 7.8 1.9 1 1 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) IncA PF04156.9 KPI45122.1 - 8.1 5.9 12.6 13 5.3 8.4 1.7 2 1 0 2 2 2 0 IncA protein Peptidase_M1 PF01433.15 KPI45124.1 - 4e-72 243.4 0.0 5.3e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KPI45124.1 - 1.1e-34 119.0 0.0 2.1e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KPI45124.1 - 6.8e-17 61.7 0.1 1.1e-16 61.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KPI45124.1 - 0.23 11.4 2.8 1.2 9.0 2.0 2.1 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Sugar_tr PF00083.19 KPI45125.1 - 5.1e-82 275.8 19.9 6.8e-82 275.4 13.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI45125.1 - 3.2e-13 49.1 39.4 1.5e-12 46.9 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 KPI45127.1 - 2.5e-17 63.5 0.0 5.3e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI45127.1 - 4.3e-12 45.6 0.0 7.7e-10 38.2 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KPI45127.1 - 1e-11 45.1 0.1 3.3e-05 23.8 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI45127.1 - 1.6e-09 36.5 0.0 2.1e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI45127.1 - 4.2e-08 33.0 0.1 0.00021 21.2 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KPI45127.1 - 9.6e-07 29.1 0.3 0.0049 17.2 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KPI45127.1 - 2.8e-06 26.6 0.3 0.05 12.6 0.3 3.2 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 KPI45127.1 - 1e-05 24.6 0.8 0.02 13.8 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 KPI45127.1 - 1.3e-05 24.4 0.3 0.01 14.9 0.0 2.4 2 0 0 2 2 2 2 Thi4 family Lycopene_cycl PF05834.7 KPI45127.1 - 4.4e-05 22.5 0.2 0.18 10.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.2 KPI45127.1 - 5.8e-05 22.3 0.1 0.0015 17.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI45127.1 - 0.00037 19.4 2.1 0.28 9.9 0.3 3.4 4 0 0 4 4 4 2 FAD binding domain Shikimate_DH PF01488.15 KPI45127.1 - 0.0011 19.1 1.0 0.019 15.0 0.0 3.1 3 1 1 4 4 3 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 KPI45127.1 - 0.0012 17.4 1.9 0.24 9.8 0.8 2.3 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.17 KPI45127.1 - 0.0014 17.5 0.2 1.3 7.8 0.0 2.6 2 0 0 2 2 2 2 Glucose inhibited division protein A IlvN PF07991.7 KPI45127.1 - 0.002 17.5 0.1 0.41 10.0 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain SnoaL_2 PF12680.2 KPI45127.1 - 0.0028 18.0 1.0 0.0061 16.9 0.7 1.5 1 0 0 1 1 1 1 SnoaL-like domain NAD_Gly3P_dh_N PF01210.18 KPI45127.1 - 0.0062 16.2 0.1 0.84 9.3 0.0 2.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 KPI45127.1 - 0.0081 16.1 0.8 0.087 12.8 0.0 2.5 3 0 0 3 3 2 1 TrkA-N domain ThiF PF00899.16 KPI45127.1 - 0.0082 15.9 0.0 0.0082 15.9 0.0 2.3 3 0 0 3 3 1 1 ThiF family NAD_binding_7 PF13241.1 KPI45127.1 - 0.026 14.7 0.0 3 8.1 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 KPI45127.1 - 0.056 13.1 3.2 0.81 9.3 0.1 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KPI45127.1 - 0.06 12.9 2.1 7.5 6.0 0.0 2.5 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.12 KPI45127.1 - 0.075 13.4 1.7 0.43 11.0 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF4440 PF14534.1 KPI45127.1 - 0.078 13.1 0.8 0.41 10.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) AdoHcyase_NAD PF00670.16 KPI45127.1 - 0.13 12.0 0.5 1 9.1 0.0 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.11 KPI45127.1 - 0.15 11.4 1.0 17 4.8 0.2 2.7 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 KPI45127.1 - 0.16 11.0 1.3 0.99 8.5 0.0 2.5 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.20 KPI45128.1 - 5.6e-72 242.0 0.0 8.2e-72 241.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI45128.1 - 2.9e-45 154.3 0.0 4.5e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI45128.1 - 3.5e-08 32.7 0.0 3.5e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KPI45128.1 - 0.09 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3439 PF11921.3 KPI45128.1 - 1.6 8.4 5.7 0.41 10.3 1.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HET PF06985.6 KPI45129.1 - 1.1e-21 77.3 10.9 8.7e-19 68.0 2.3 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Vac7 PF12751.2 KPI45130.1 - 2.1e-115 385.6 9.0 2.1e-115 385.6 6.2 1.6 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 DUF2681 PF10883.3 KPI45131.1 - 0.057 13.6 0.0 0.096 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Auxin_repressed PF05564.7 KPI45131.1 - 1.4 9.5 11.6 2.1 8.9 3.7 2.5 2 1 0 2 2 2 0 Dormancy/auxin associated protein Pro_Al_protease PF02983.9 KPI45132.1 - 0.062 13.2 0.7 0.13 12.2 0.5 1.5 1 0 0 1 1 1 0 Alpha-lytic protease prodomain DUF3453 PF11935.3 KPI45133.1 - 1.5e-62 211.1 0.1 1e-61 208.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) DUF3431 PF11913.3 KPI45134.1 - 1.9e-80 269.5 0.0 2.4e-80 269.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Clr5 PF14420.1 KPI45136.1 - 9.5e-11 41.4 1.1 2.1e-10 40.3 0.0 2.2 2 0 0 2 2 2 1 Clr5 domain TPR_14 PF13428.1 KPI45136.1 - 2.1 9.2 4.9 17 6.3 0.2 4.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 KPI45136.1 - 7.1 6.8 7.1 4 7.5 0.2 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat adh_short PF00106.20 KPI45137.1 - 1.5e-20 73.7 0.3 2.7e-20 72.9 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI45137.1 - 3.9e-13 49.7 0.0 9.5e-13 48.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI45137.1 - 7.2e-09 35.5 0.0 2.1e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI45137.1 - 0.00015 21.8 0.0 0.00034 20.6 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI45137.1 - 0.00061 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI45137.1 - 0.00083 18.1 0.0 0.0012 17.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KPI45137.1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 KPI45137.1 - 0.032 13.1 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.14 KPI45137.1 - 0.099 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Arginase PF00491.16 KPI45138.1 - 6.5e-24 84.6 0.0 7.6e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family Amino_oxidase PF01593.19 KPI45139.1 - 4.8e-38 131.3 0.1 2.3e-37 129.1 0.1 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KPI45139.1 - 6.2e-06 26.1 0.0 1.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KPI45139.1 - 0.018 14.1 0.4 0.032 13.2 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 KPI45139.1 - 0.027 14.5 0.1 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.27 KPI45140.1 - 2.4e-14 52.5 5.0 6.9e-06 25.7 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF2406 PF10295.4 KPI45141.1 - 1.9e-17 63.5 6.1 5.2e-16 58.9 4.2 3.0 1 1 0 1 1 1 1 Uncharacterised protein (DUF2406) AFG1_ATPase PF03969.11 KPI45142.1 - 2.2e-61 207.6 0.0 1.8e-59 201.3 0.0 2.2 2 0 0 2 2 2 1 AFG1-like ATPase GMC_oxred_N PF00732.14 KPI45142.1 - 8.5e-51 172.8 0.0 1.2e-50 172.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI45142.1 - 3.2e-22 79.3 0.0 8.3e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase AAA_5 PF07728.9 KPI45142.1 - 5e-05 23.0 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DAO PF01266.19 KPI45142.1 - 0.0048 15.8 0.0 0.016 14.1 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI45142.1 - 0.0088 14.9 0.2 0.067 12.0 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KPI45142.1 - 0.012 15.6 1.0 0.045 13.7 0.7 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI45142.1 - 0.036 13.9 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AAA_16 PF13191.1 KPI45142.1 - 0.041 13.8 0.1 0.34 10.8 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain VRR_NUC PF08774.6 KPI45143.1 - 6.4e-16 58.2 0.0 1.9e-15 56.6 0.0 1.8 2 0 0 2 2 2 1 VRR-NUC domain DUF1708 PF08101.6 KPI45144.1 - 6.4e-142 473.2 0.0 8.3e-142 472.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF605 PF04652.11 KPI45145.1 - 9.7 5.4 14.3 18 4.5 9.9 1.5 1 0 0 1 1 1 0 Vta1 like IBR PF01485.16 KPI45146.1 - 3.5e-13 49.2 32.9 1.4e-07 31.2 7.2 3.5 2 2 1 3 3 3 2 IBR domain zf-RING_2 PF13639.1 KPI45146.1 - 0.013 15.2 3.4 0.013 15.2 2.4 3.2 3 0 0 3 3 3 0 Ring finger domain zf-RING_5 PF14634.1 KPI45146.1 - 0.017 14.8 3.4 0.017 14.8 2.4 3.2 3 0 0 3 3 3 0 zinc-RING finger domain Peptidase_M35 PF02102.10 KPI45147.1 - 2.1e-05 23.3 0.1 3.2e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Afi1 PF07792.7 KPI45148.1 - 1.3e-59 200.3 0.0 2.4e-59 199.5 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 KPI45148.1 - 3.9e-36 123.2 0.0 9.6e-36 121.9 0.0 1.7 2 0 0 2 2 2 1 Stabilization of polarity axis Avl9 PF09794.4 KPI45148.1 - 2.8e-09 35.9 0.0 0.00096 17.7 0.0 3.8 2 2 1 3 3 3 3 Transport protein Avl9 DUF2347 PF09804.4 KPI45148.1 - 0.00054 19.3 0.0 0.022 14.0 0.0 3.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) PNGaseA PF12222.3 KPI45149.1 - 3.3e-94 316.1 3.6 1.2e-82 278.1 0.7 2.1 1 1 1 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Arf PF00025.16 KPI45149.1 - 3.9e-58 195.5 0.0 5.6e-58 195.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KPI45149.1 - 2e-08 33.3 0.0 1.8e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KPI45149.1 - 9.5e-07 28.1 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KPI45149.1 - 3.8e-06 26.8 0.0 6.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KPI45149.1 - 0.00016 22.1 0.0 0.00031 21.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KPI45149.1 - 0.00053 19.4 0.0 0.0013 18.1 0.0 1.6 2 0 0 2 2 2 1 Ras family Gtr1_RagA PF04670.7 KPI45149.1 - 0.002 17.3 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AA_permease PF00324.16 KPI45150.1 - 1.2e-129 432.7 34.0 1.4e-129 432.5 23.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI45150.1 - 2.8e-39 134.8 36.5 3.9e-39 134.3 25.3 1.1 1 0 0 1 1 1 1 Amino acid permease DIOX_N PF14226.1 KPI45151.1 - 0.068 13.7 0.0 0.12 12.9 0.0 1.5 1 1 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal PhyH PF05721.8 KPI45151.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Methyltransf_28 PF02636.12 KPI45152.1 - 4.2e-35 121.3 0.0 6.8e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RELT PF12606.3 KPI45153.1 - 0.48 9.5 0.8 1.9 7.6 0.5 2.0 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Glyco_hydro_18 PF00704.23 KPI45154.1 - 4.7e-05 23.0 0.0 6.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Phage_CRI PF05144.9 KPI45154.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.3 1 1 0 1 1 1 0 Phage replication protein CRI MFS_1 PF07690.11 KPI45156.1 - 1e-33 116.5 23.7 1e-33 116.5 16.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TIM-br_sig_trns PF09370.5 KPI45157.1 - 9e-122 405.2 0.2 1.3e-121 404.7 0.1 1.2 1 0 0 1 1 1 1 TIM-barrel signal transduction protein ABC_tran PF00005.22 KPI45158.1 - 3.3e-09 37.1 0.0 4.4e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter Telomere_reg-2 PF10193.4 KPI45160.1 - 1.9e-20 73.1 0.1 5.1e-19 68.6 0.0 3.1 2 1 0 2 2 2 1 Telomere length regulation protein Amidase PF01425.16 KPI45161.1 - 6.2e-75 252.7 4.0 7.9e-75 252.3 2.7 1.1 1 0 0 1 1 1 1 Amidase RNA_GG_bind PF10258.4 KPI45161.1 - 0.039 13.6 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 PHAX RNA-binding domain tRNA-synt_2 PF00152.15 KPI45162.1 - 5e-74 249.0 0.0 7.6e-74 248.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 KPI45162.1 - 1.6e-08 33.7 0.0 2.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 KPI45162.1 - 0.00059 19.6 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2401 PF10287.4 KPI45163.1 - 1.5e-75 253.6 0.0 2.5e-75 252.9 0.0 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 KPI45163.1 - 1.8e-23 82.4 0.0 5e-23 81.0 0.0 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) ADH_N PF08240.7 KPI45166.1 - 2.9e-20 72.0 0.3 5.7e-20 71.1 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI45166.1 - 3e-18 65.5 0.1 5.5e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KPI45166.1 - 1.4e-06 27.7 0.5 1.4e-06 27.7 0.4 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.1 KPI45166.1 - 0.0073 17.2 0.0 0.013 16.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 KPI45166.1 - 0.2 11.7 0.5 0.32 11.0 0.4 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CPSF_A PF03178.10 KPI45167.1 - 4.5e-69 232.9 0.0 5.1e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 CPSF A subunit region Adaptin_N PF01602.15 KPI45168.1 - 1.8e-111 373.0 0.1 2.5e-111 372.6 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KPI45168.1 - 1.1e-55 187.5 3.1 2.5e-55 186.4 2.1 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KPI45168.1 - 2.3e-14 53.4 3.8 2.3e-05 24.5 0.0 6.1 2 2 4 6 6 6 5 HEAT repeats HEAT_PBS PF03130.11 KPI45168.1 - 0.018 15.4 0.1 9.2 7.0 0.0 3.6 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat HEAT PF02985.17 KPI45168.1 - 0.025 14.6 9.6 0.58 10.3 0.2 5.3 6 0 0 6 6 6 0 HEAT repeat DUF3730 PF12530.3 KPI45168.1 - 0.031 14.1 0.9 0.17 11.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) HEAT_EZ PF13513.1 KPI45168.1 - 0.048 14.1 3.3 0.14 12.7 0.6 2.9 2 0 0 2 2 2 0 HEAT-like repeat RICTOR_M PF14666.1 KPI45168.1 - 0.5 9.3 2.9 15 4.4 0.0 3.3 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain Asp_protease_2 PF13650.1 KPI45169.1 - 0.014 15.8 0.0 0.037 14.5 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.1 KPI45169.1 - 0.084 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Ribosomal_L29e PF01779.12 KPI45170.1 - 1.9e-08 34.0 0.5 3.6e-08 33.1 0.3 1.5 1 0 0 1 1 1 1 Ribosomal L29e protein family Vps5 PF09325.5 KPI45171.1 - 1.6e-72 243.5 1.5 1.6e-72 243.5 1.1 1.6 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 KPI45171.1 - 7.3e-26 90.1 0.1 1.4e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 KPI45171.1 - 0.027 13.7 0.3 1.1 8.5 0.0 2.2 1 1 1 2 2 2 0 WASP-binding domain of Sorting nexin protein DLH PF01738.13 KPI45173.1 - 2.9e-22 79.0 0.0 3.3e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KPI45173.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI45173.1 - 0.015 14.5 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KPI45173.1 - 0.079 12.3 0.1 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase RhoGAP PF00620.22 KPI45174.1 - 4.2e-35 120.6 0.1 8.3e-35 119.6 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KPI45174.1 - 8e-33 112.3 34.8 7.5e-13 48.3 4.2 4.8 5 0 0 5 5 5 4 LIM domain IDO PF01231.13 KPI45175.1 - 4.2e-146 486.6 0.0 4.9e-146 486.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase KR PF08659.5 KPI45176.1 - 7.3e-62 208.2 0.5 7.3e-62 208.2 0.3 3.7 5 0 0 5 5 5 1 KR domain Acyl_transf_1 PF00698.16 KPI45176.1 - 1.3e-58 198.8 1.3 1.5e-58 198.6 0.2 1.7 2 0 0 2 2 2 1 Acyl transferase domain adh_short PF00106.20 KPI45176.1 - 1.2e-45 155.3 0.3 1.2e-45 155.3 0.2 3.4 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 KPI45176.1 - 3.5e-44 151.1 0.0 7.8e-44 150.0 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 KPI45176.1 - 5.3e-42 144.0 0.0 5e-32 111.3 0.0 2.7 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KPI45176.1 - 4.2e-37 126.6 0.1 1.1e-36 125.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KPI45176.1 - 5.3e-24 84.2 1.5 1.1e-22 80.0 0.1 3.2 4 0 0 4 4 3 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KPI45176.1 - 1.1e-18 67.5 0.0 9.7e-18 64.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI45176.1 - 5.2e-13 48.8 0.0 1.2e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KPI45176.1 - 1.7e-12 48.3 0.3 3.7e-11 44.0 0.0 3.4 4 0 0 4 4 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KPI45176.1 - 3.3e-12 46.4 0.0 8e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI45176.1 - 3.5e-11 43.4 0.0 1.5e-10 41.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI45176.1 - 6e-10 39.6 0.0 3.2e-09 37.3 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 KPI45176.1 - 2.6e-06 27.1 0.1 5.8e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_25 PF13649.1 KPI45176.1 - 6.5e-06 26.4 0.0 2.9e-05 24.3 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI45176.1 - 2.8e-05 23.3 0.0 0.0001 21.4 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 KPI45176.1 - 0.13 11.6 0.0 0.59 9.4 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) DUF3336 PF11815.3 KPI45177.1 - 1.1e-33 115.8 0.8 2.1e-33 114.8 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KPI45177.1 - 6.5e-20 71.9 0.1 2.2e-19 70.2 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase Glyco_hydro_63 PF03200.11 KPI45178.1 - 1.7e-07 29.4 5.4 5.4e-06 24.5 0.2 3.4 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase zf-RING_2 PF13639.1 KPI45179.1 - 2.2e-06 27.4 8.4 3.3e-06 26.8 5.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KPI45179.1 - 2.1e-05 24.0 5.2 3e-05 23.5 3.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI45179.1 - 0.00035 20.2 5.9 0.00055 19.6 4.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KPI45179.1 - 0.0083 16.1 8.3 0.029 14.3 5.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KPI45179.1 - 0.042 13.9 6.0 0.078 13.0 4.2 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 KPI45179.1 - 0.34 10.6 8.2 1.3 8.7 6.1 1.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4206 PF13901.1 KPI45179.1 - 0.36 10.3 4.0 0.54 9.7 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) FANCL_C PF11793.3 KPI45179.1 - 2.4 8.1 7.8 9.7 6.2 5.4 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Pyr_redox_3 PF13738.1 KPI45180.1 - 1.2e-23 84.2 0.0 8.7e-23 81.4 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI45180.1 - 9.1e-08 30.7 0.0 8.6e-07 27.5 0.0 2.3 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KPI45180.1 - 2.6e-06 27.4 0.0 0.036 13.9 0.0 3.4 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI45180.1 - 0.00014 20.8 0.0 0.00067 18.6 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KPI45180.1 - 0.00021 21.1 0.0 0.015 15.1 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KPI45180.1 - 0.00036 20.5 0.1 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KPI45180.1 - 0.00053 20.0 0.0 0.0026 17.8 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KPI45180.1 - 0.013 15.8 1.8 0.037 14.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KPI45180.1 - 0.03 14.5 0.6 0.076 13.2 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_oxidored PF12831.2 KPI45180.1 - 0.04 13.0 0.9 0.1 11.6 0.6 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF498 PF04430.9 KPI45180.1 - 0.07 12.6 0.0 15 5.2 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) FAD_binding_2 PF00890.19 KPI45180.1 - 0.1 11.4 0.3 0.19 10.5 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain DHDPS PF00701.17 KPI45182.1 - 1.5e-39 135.3 0.0 1.9e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 KPI45182.1 - 0.016 14.4 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase AP_endonuc_2 PF01261.19 KPI45182.1 - 0.032 13.4 0.0 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel WD40 PF00400.27 KPI45183.1 - 0.00043 20.0 8.5 1.2 9.1 0.1 5.1 4 1 0 4 4 4 2 WD domain, G-beta repeat PQQ PF01011.16 KPI45183.1 - 0.0094 15.4 0.1 0.036 13.6 0.1 2.0 1 0 0 1 1 1 1 PQQ enzyme repeat Coatomer_WDAD PF04053.9 KPI45183.1 - 0.01 14.6 0.1 0.021 13.6 0.0 1.4 2 0 0 2 2 2 0 Coatomer WD associated region LisH PF08513.6 KPI45183.1 - 0.021 14.5 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 LisH eIF2A PF08662.6 KPI45183.1 - 0.077 12.6 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A p450 PF00067.17 KPI45184.1 - 6e-93 311.8 0.0 7.4e-93 311.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Remorin_N PF03766.8 KPI45185.1 - 0.0083 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Remorin, N-terminal region XPG_I PF00867.13 KPI45187.1 - 2.3e-30 104.4 0.0 6.3e-30 103.0 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KPI45187.1 - 2e-16 60.0 0.0 7.2e-16 58.3 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KPI45187.1 - 1.4e-06 28.4 0.2 1.4e-05 25.2 0.0 2.6 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold TniB PF05621.6 KPI45187.1 - 0.0097 14.7 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein Glyco_trans_2_3 PF13632.1 KPI45188.1 - 1.8e-42 145.2 5.6 1.8e-42 145.2 3.9 2.9 4 1 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KPI45188.1 - 7.3e-08 32.4 0.0 6.6e-06 26.0 0.1 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KPI45188.1 - 0.00095 18.8 0.0 0.0038 16.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KPI45188.1 - 0.0057 15.9 0.0 0.017 14.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 SnoaL_4 PF13577.1 KPI45189.1 - 1.2e-05 25.2 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain p450 PF00067.17 KPI45191.1 - 2.2e-61 207.8 0.0 2.9e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DnaJ PF00226.26 KPI45192.1 - 1.4e-23 82.3 0.8 2.7e-23 81.4 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KPI45192.1 - 1.6e-14 53.6 20.0 2.6e-14 52.9 13.8 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 KPI45192.1 - 2.1e-11 43.5 0.0 7.9e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 KPI45192.1 - 0.034 13.8 8.1 1.1 9.0 0.4 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Abhydrolase_3 PF07859.8 KPI45194.1 - 2.5e-42 144.8 0.0 9.3e-30 103.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 KPI45194.1 - 1.4e-06 27.3 0.0 1.4e-06 27.3 0.0 2.2 2 1 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 KPI45194.1 - 0.0002 20.6 1.8 0.051 12.7 0.0 3.1 2 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KPI45194.1 - 0.0074 16.0 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KPI45194.1 - 0.04 12.4 0.0 0.55 8.6 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF605 PF04652.11 KPI45194.1 - 0.63 9.3 8.8 0.79 9.0 6.1 1.2 1 0 0 1 1 1 0 Vta1 like SIR2 PF02146.12 KPI45195.1 - 5.5e-30 104.4 0.0 8.1e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family zf-H2C2_2 PF13465.1 KPI45199.1 - 3.2e-12 46.0 13.3 3e-06 27.2 0.2 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KPI45199.1 - 1.2e-09 37.8 14.2 1.6e-05 24.9 3.1 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI45199.1 - 5e-08 32.7 9.0 0.00016 21.7 1.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KPI45199.1 - 2.7e-06 27.3 1.5 1.6e-05 24.9 1.0 2.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KPI45199.1 - 1.6e-05 24.8 4.6 9.7e-05 22.3 1.4 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KPI45199.1 - 0.00011 21.9 6.9 0.0032 17.2 1.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KPI45199.1 - 0.043 13.9 1.3 0.043 13.9 0.9 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 KPI45199.1 - 0.4 10.3 3.3 6.1 6.6 0.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.1 KPI45199.1 - 1.2 9.4 6.6 4.1 7.8 1.0 3.1 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.10 KPI45199.1 - 6 6.7 9.2 30 4.4 5.2 2.7 2 1 0 2 2 2 0 BED zinc finger Nuc_sug_transp PF04142.10 KPI45200.1 - 5.4e-80 268.0 17.8 9.3e-80 267.2 12.4 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KPI45200.1 - 1.3e-10 40.7 16.7 2.3e-10 39.9 11.6 1.4 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KPI45200.1 - 1.6e-06 27.8 5.8 1.6e-06 27.8 4.1 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 KPI45200.1 - 4.4e-06 26.8 3.3 4.4e-06 26.8 2.3 3.1 3 1 1 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 KPI45200.1 - 0.00041 20.4 3.8 0.00041 20.4 2.6 2.6 2 1 0 2 2 2 1 EamA-like transporter family Pex24p PF06398.6 KPI45200.1 - 0.1 11.3 0.6 0.27 9.9 0.0 1.9 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF3602 PF12223.3 KPI45201.1 - 4e-13 49.5 8.9 1.3e-12 47.9 2.8 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) MFS_1 PF07690.11 KPI45202.1 - 6.7e-31 107.2 21.0 6.7e-31 107.2 14.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KPI45202.1 - 0.0046 16.7 0.9 0.037 13.8 0.1 2.7 3 0 0 3 3 3 1 MFS_1 like family SNF2_N PF00176.18 KPI45204.1 - 8.9e-64 215.1 0.0 1.4e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KPI45204.1 - 1e-10 41.3 0.0 2.1e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KPI45204.1 - 1.3e-06 28.0 0.1 4.9e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 KPI45204.1 - 0.021 14.5 4.9 0.041 13.6 3.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Endonuclease_7 PF02945.10 KPI45204.1 - 0.041 13.5 1.3 0.11 12.1 0.9 1.8 1 0 0 1 1 1 0 Recombination endonuclease VII zf-C3HC4_2 PF13923.1 KPI45204.1 - 0.17 11.9 1.8 0.42 10.6 1.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Chal_sti_synt_N PF00195.14 KPI45205.1 - 9.9e-26 90.3 0.0 1.3e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 KPI45205.1 - 2.4e-13 50.2 0.0 4.4e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.7 KPI45205.1 - 7.7e-09 35.0 0.3 1.7e-08 33.8 0.2 1.5 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.5 KPI45205.1 - 1.3e-05 24.7 0.2 3.6e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 KPI45205.1 - 0.0094 15.9 0.0 0.052 13.5 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal NPV_P10 PF05531.7 KPI45206.1 - 1.8 8.8 10.3 79 3.6 0.1 5.2 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 KPI45206.1 - 5.9 6.3 13.1 3.5 7.1 0.7 2.8 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) adh_short PF00106.20 KPI45207.1 - 1.2e-15 57.8 0.1 2.8e-15 56.6 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI45207.1 - 0.00015 21.4 0.1 0.00077 19.1 0.1 1.9 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KPI45207.1 - 0.0037 17.0 0.0 0.018 14.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Abhydrolase_6 PF12697.2 KPI45208.1 - 1.7e-16 60.7 1.7 2.6e-15 56.9 0.2 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI45208.1 - 9.7e-12 44.8 0.0 1.9e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KPI45208.1 - 5e-08 32.6 0.1 1.6e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 KPI45208.1 - 9.2e-05 22.1 0.0 0.00033 20.2 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI45208.1 - 0.00033 19.9 0.0 0.1 11.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Acetyltransf_7 PF13508.1 KPI45208.1 - 0.00039 20.5 0.0 0.001 19.1 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Esterase PF00756.15 KPI45208.1 - 0.0014 18.1 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 KPI45208.1 - 0.006 16.1 0.0 0.031 13.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Acetyltransf_1 PF00583.19 KPI45208.1 - 0.0097 15.9 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KPI45208.1 - 0.068 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Abhydrolase_2 PF02230.11 KPI45208.1 - 0.068 12.5 0.0 5.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase zf-met PF12874.2 KPI45209.1 - 0.012 15.8 1.1 3.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF3700 PF12481.3 KPI45209.1 - 0.063 12.4 0.0 0.089 11.9 0.0 1.1 1 0 0 1 1 1 0 Aluminium induced protein HPP PF04982.8 KPI45210.1 - 3.8e-20 71.9 6.0 6.2e-20 71.2 4.1 1.3 1 0 0 1 1 1 1 HPP family DLH PF01738.13 KPI45211.1 - 4.9e-16 58.6 0.0 6.1e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KPI45211.1 - 0.00082 19.1 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI45211.1 - 0.0022 17.5 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans PF04082.13 KPI45212.1 - 2.2e-18 66.0 0.1 2.2e-18 66.0 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI45212.1 - 2.7e-06 27.1 11.4 4.4e-06 26.5 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IncA PF04156.9 KPI45213.1 - 0.0011 18.5 2.6 0.0011 18.5 1.8 1.9 2 0 0 2 2 2 1 IncA protein F-box PF00646.28 KPI45213.1 - 0.0014 18.2 0.0 0.0037 16.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain Fmp27_WPPW PF10359.4 KPI45213.1 - 0.006 15.0 0.9 0.0097 14.3 0.6 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain CCDC155 PF14662.1 KPI45213.1 - 0.0073 15.9 1.9 0.015 14.8 1.3 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Filament PF00038.16 KPI45213.1 - 0.017 14.6 1.4 0.035 13.5 1.0 1.5 1 0 0 1 1 1 0 Intermediate filament protein RmuC PF02646.11 KPI45213.1 - 0.028 13.2 1.7 0.054 12.3 1.2 1.4 1 0 0 1 1 1 0 RmuC family ADIP PF11559.3 KPI45213.1 - 0.078 12.8 2.8 0.22 11.4 1.9 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.6 KPI45213.1 - 0.12 12.0 1.4 0.31 10.7 1.0 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Ax_dynein_light PF10211.4 KPI45213.1 - 0.18 11.5 4.1 0.4 10.5 1.5 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain DUF4200 PF13863.1 KPI45213.1 - 0.28 11.1 5.8 0.049 13.5 1.4 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.4 KPI45213.1 - 0.35 10.7 7.3 0.057 13.2 0.8 2.4 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2205 PF10224.4 KPI45213.1 - 0.36 10.4 3.4 0.15 11.6 0.6 1.7 2 0 0 2 2 1 0 Predicted coiled-coil protein (DUF2205) TBPIP PF07106.8 KPI45213.1 - 0.41 10.1 3.3 0.95 8.9 2.3 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) OmpH PF03938.9 KPI45213.1 - 0.6 10.0 6.3 0.52 10.2 3.0 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Tropomyosin_1 PF12718.2 KPI45213.1 - 0.62 9.9 8.6 0.17 11.7 3.3 1.8 2 0 0 2 2 2 0 Tropomyosin like DUF724 PF05266.9 KPI45213.1 - 1.3 8.6 8.6 0.69 9.5 3.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF4140 PF13600.1 KPI45213.1 - 5.3 7.5 7.5 1.3 9.4 2.4 2.1 3 0 0 3 3 1 0 N-terminal domain of unknown function (DUF4140) Amidohydro_1 PF01979.15 KPI45214.1 - 8.3e-36 124.2 0.7 1.5e-35 123.3 0.5 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KPI45214.1 - 1.8e-07 30.7 0.1 4.7e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KPI45214.1 - 1.8e-06 28.1 0.1 9.4e-05 22.5 0.0 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KPI45214.1 - 4.7e-06 26.3 0.0 1.5e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase DUF2070 PF09843.4 KPI45214.1 - 0.067 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Sugar_tr PF00083.19 KPI45215.1 - 1.3e-78 264.5 29.3 1.6e-78 264.3 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI45215.1 - 2.1e-29 102.3 25.0 2.1e-29 102.3 17.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_28 PF03033.15 KPI45216.1 - 6.8e-18 64.7 0.0 2.6e-17 62.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KPI45216.1 - 1.2e-05 24.0 0.0 1.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 KPI45216.1 - 5.2e-05 23.3 0.0 0.00014 21.9 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain Glyco_tran_28_C PF04101.11 KPI45216.1 - 0.034 13.8 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain But2 PF09792.4 KPI45217.1 - 6.9e-22 77.7 1.8 8.8e-22 77.3 1.2 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Topoisom_I_N PF02919.10 KPI45218.1 - 8.2e-97 322.6 4.5 8.2e-97 322.6 3.1 3.6 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KPI45218.1 - 2.2e-83 278.9 8.5 2.2e-83 278.9 5.9 2.8 2 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KPI45218.1 - 1.1e-32 111.4 0.8 5.7e-32 109.1 0.5 2.4 1 0 0 1 1 1 1 C-terminal topoisomerase domain HLH PF00010.21 KPI45219.1 - 0.0012 18.5 0.0 0.0027 17.3 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PhyH PF05721.8 KPI45221.1 - 4.6e-21 75.8 0.0 6.1e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Serinc PF03348.10 KPI45222.1 - 5.5e-05 22.0 0.1 7.9e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) MARVEL PF01284.18 KPI45222.1 - 0.11 12.3 8.7 0.39 10.5 5.9 2.0 1 1 1 2 2 2 0 Membrane-associating domain LRR_6 PF13516.1 KPI45223.1 - 9.1e-14 49.9 2.7 0.027 14.5 0.0 7.4 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 KPI45223.1 - 8.8e-11 41.1 5.8 0.025 14.2 0.0 6.6 3 2 4 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KPI45223.1 - 1.9e-06 27.1 2.3 16 6.0 0.0 7.1 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.1 KPI45223.1 - 0.00056 19.6 5.6 19 5.1 0.0 5.5 3 2 2 5 5 5 2 Leucine rich repeat LRR_7 PF13504.1 KPI45223.1 - 0.0088 16.0 1.1 1.3e+02 3.5 0.0 6.4 8 0 0 8 8 8 0 Leucine rich repeat Astro_capsid PF03115.9 KPI45223.1 - 0.36 9.0 1.4 0.43 8.7 1.0 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor HAD_2 PF13419.1 KPI45224.1 - 1.2e-23 84.2 0.0 2.3e-23 83.3 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KPI45224.1 - 2.3e-09 37.9 0.0 3.8e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KPI45224.1 - 0.00045 19.8 0.0 0.00085 18.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NUFIP1 PF10453.4 KPI45225.1 - 2.3e-11 43.0 1.7 2.3e-11 43.0 1.1 2.2 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 KPI45225.1 - 3.7e-07 29.6 5.1 8.1e-07 28.5 3.5 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRV_FeS PF05484.6 KPI45225.1 - 0.045 13.3 0.7 0.081 12.5 0.5 1.3 1 0 0 1 1 1 0 LRV protein FeS4 cluster DUF4407 PF14362.1 KPI45225.1 - 7.5 5.4 13.6 12 4.7 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SRF-TF PF00319.13 KPI45226.1 - 6.1e-24 82.9 0.1 9.5e-24 82.3 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1829 PF08862.5 KPI45227.1 - 0.001 19.3 0.1 36 4.7 0.0 5.1 2 1 5 8 8 8 3 Domain of unknown function DUF1829 Pirin PF02678.11 KPI45228.1 - 4.5e-32 110.0 0.2 3.6e-31 107.2 0.1 2.1 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 KPI45228.1 - 2.9e-25 88.3 0.0 6.6e-24 83.9 0.0 2.3 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 KPI45228.1 - 6.2e-06 25.6 0.5 0.0002 20.7 0.2 2.3 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 KPI45228.1 - 0.018 14.3 0.1 0.062 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) EthD PF07110.6 KPI45229.1 - 0.00012 22.9 0.0 0.00019 22.3 0.0 1.4 1 0 0 1 1 1 1 EthD domain MmgE_PrpD PF03972.9 KPI45231.1 - 2.8e-34 118.0 0.1 3.4e-34 117.8 0.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Peroxin-13_N PF04088.8 KPI45232.1 - 1.4e-33 116.0 1.3 2.5e-33 115.2 0.9 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region Lactamase_B_2 PF12706.2 KPI45234.1 - 1.2e-21 77.1 0.0 2.2e-21 76.2 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KPI45234.1 - 5.3e-12 45.7 2.2 2.5e-11 43.5 1.5 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KPI45234.1 - 0.0048 16.5 8.1 0.011 15.3 3.7 2.6 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily End3 PF12761.2 KPI45235.1 - 4e-64 215.8 1.5 5.8e-64 215.3 1.0 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 KPI45235.1 - 2.3e-47 158.9 0.0 3.1e-45 152.1 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KPI45235.1 - 4.3e-08 31.8 0.4 4e-07 28.8 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KPI45235.1 - 2.4e-06 27.0 0.4 2.5e-05 23.7 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 KPI45235.1 - 2.7e-06 27.4 0.2 0.00017 21.6 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 KPI45235.1 - 1.1e-05 24.9 0.3 0.00025 20.6 0.2 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 KPI45235.1 - 0.0011 18.2 0.2 0.0026 17.0 0.2 1.7 1 0 0 1 1 1 1 EF hand CENP-F_leu_zip PF10473.4 KPI45235.1 - 0.027 14.3 1.6 0.027 14.3 1.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 KPI45235.1 - 0.042 13.5 0.9 0.042 13.5 0.6 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF641 PF04859.7 KPI45235.1 - 1.8 8.2 6.6 0.47 10.2 1.3 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Fungal_trans PF04082.13 KPI45236.1 - 0.0044 15.9 0.4 0.0088 14.9 0.0 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KPI45237.1 - 0.08 13.3 24.0 0.36 11.2 0.3 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type 2-Hacid_dh_C PF02826.14 KPI45238.1 - 4.6e-46 156.1 0.0 9.6e-46 155.1 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KPI45238.1 - 0.00058 20.0 0.0 0.0042 17.3 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding XdhC_C PF13478.1 KPI45238.1 - 0.00091 19.5 0.1 0.0023 18.2 0.0 1.7 2 0 0 2 2 2 1 XdhC Rossmann domain ELFV_dehydrog PF00208.16 KPI45238.1 - 0.0017 17.9 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pyr_redox PF00070.22 KPI45238.1 - 0.0042 17.4 0.0 0.0082 16.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh PF00389.25 KPI45238.1 - 0.0046 16.4 0.0 0.013 14.9 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_10 PF13460.1 KPI45238.1 - 0.031 14.3 0.3 0.053 13.5 0.1 1.6 2 0 0 2 2 2 0 NADH(P)-binding AdoHcyase_NAD PF00670.16 KPI45238.1 - 0.034 13.9 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.13 KPI45238.1 - 0.12 12.3 0.0 0.34 10.9 0.0 1.8 1 1 0 1 1 1 0 TrkA-N domain DUF3694 PF12473.3 KPI45239.1 - 6.5e-35 119.8 0.1 1.2e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 KPI45239.1 - 0.00017 21.7 0.0 0.00071 19.7 0.0 2.0 2 0 0 2 2 2 1 PH domain IGF2_C PF08365.6 KPI45239.1 - 0.34 10.7 2.5 0.77 9.5 0.2 2.3 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide NAD_binding_10 PF13460.1 KPI45240.1 - 6.3e-05 23.0 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI45240.1 - 0.0002 20.9 0.0 0.00045 19.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KPI45240.1 - 0.0018 17.2 0.0 0.59 9.0 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KPI45241.1 - 1.5e-06 28.3 0.0 2e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI45241.1 - 0.014 14.8 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ldl_recept_b PF00058.12 KPI45241.1 - 0.063 13.6 0.4 0.13 12.6 0.1 1.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor repeat class B Polysacc_synt_2 PF02719.10 KPI45241.1 - 0.064 12.1 0.0 0.087 11.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 KPI45241.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.3 KPI45242.1 - 0.00048 18.8 0.0 0.00075 18.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Med25_SD1 PF11235.3 KPI45242.1 - 0.036 14.3 3.7 0.066 13.5 2.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 WHG PF13305.1 KPI45242.1 - 0.073 13.6 0.2 6.1 7.4 0.0 2.8 3 0 0 3 3 3 0 WHG domain HSP90 PF00183.13 KPI45243.1 - 2.1e-64 217.8 32.8 3.7e-46 157.6 5.4 3.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.21 KPI45243.1 - 1.2e-11 44.3 0.0 1.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KPI45243.1 - 3.6e-11 42.8 0.2 3.6e-11 42.8 0.2 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF399 PF04187.8 KPI45243.1 - 0.083 12.3 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF399 YqfQ PF14181.1 KPI45243.1 - 3 7.8 7.3 9 6.3 5.1 1.8 1 0 0 1 1 1 0 YqfQ-like protein CENP-B_dimeris PF09026.5 KPI45243.1 - 8.6 6.6 18.4 1.1 9.5 5.0 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GST_C PF00043.20 KPI45244.1 - 1.9e-10 40.5 0.0 3.4e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI45244.1 - 1.3e-07 31.4 0.0 2.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KPI45244.1 - 0.00024 21.5 0.0 0.00045 20.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cys_Met_Meta_PP PF01053.15 KPI45247.1 - 8.6e-135 448.9 0.1 1e-134 448.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RNA_pol_Rbc25 PF08292.7 KPI45247.1 - 7e-30 103.7 0.0 1.1e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KPI45247.1 - 3.5e-15 55.8 0.0 1.2e-14 54.1 0.0 2.0 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Aminotran_1_2 PF00155.16 KPI45247.1 - 5e-09 35.5 0.0 7.8e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KPI45247.1 - 6.9e-07 28.3 0.4 2.8e-06 26.3 0.1 1.9 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KPI45247.1 - 3.6e-06 26.2 0.1 6.1e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KPI45247.1 - 0.0011 18.2 0.0 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 KPI45247.1 - 0.032 12.9 0.1 0.061 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage system P-protein RRM_1 PF00076.17 KPI45248.1 - 1.4e-13 50.2 0.1 7.6e-10 38.2 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI45248.1 - 2.2e-13 49.9 0.5 3.9e-09 36.3 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI45248.1 - 4.4e-12 45.6 0.0 1.7e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4187 PF13821.1 KPI45249.1 - 1.8e-17 62.6 1.6 5.4e-17 61.1 1.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 KPI45249.1 - 1.1e-10 41.1 0.2 2.6e-10 39.8 0.2 1.7 1 0 0 1 1 1 1 G-patch domain Tyrosinase PF00264.15 KPI45250.1 - 8.6e-53 179.7 6.7 1e-52 179.5 4.0 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase AdoHcyase PF05221.12 KPI45251.1 - 3.8e-135 449.0 0.1 4.4e-135 448.8 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KPI45251.1 - 2.3e-83 277.8 2.3 3.6e-83 277.2 1.6 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KPI45251.1 - 2e-06 27.1 0.2 3.9e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KPI45251.1 - 0.0019 17.6 0.2 0.0033 16.8 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ELFV_dehydrog PF00208.16 KPI45251.1 - 0.0044 16.6 0.1 0.0078 15.8 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 KPI45251.1 - 0.024 14.6 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DUF4448 PF14610.1 KPI45251.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SH3_2 PF07653.12 KPI45252.1 - 2.1e-10 39.8 0.0 3.3e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KPI45252.1 - 2.8e-10 39.3 0.0 4.8e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KPI45252.1 - 1.4e-07 30.9 0.0 2.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Peroxin-13_N PF04088.8 KPI45252.1 - 5.9e-06 26.3 0.1 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_3 PF08239.6 KPI45252.1 - 0.022 14.9 0.1 0.054 13.6 0.0 1.7 2 0 0 2 2 2 0 Bacterial SH3 domain hSH3 PF14603.1 KPI45252.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Helically-extended SH3 domain THF_DHG_CYH PF00763.18 KPI45256.1 - 1.1e-18 67.3 0.2 1.7e-18 66.7 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 KPI45256.1 - 3.7e-12 45.6 0.0 3.7e-09 35.8 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HXXSHH PF07586.6 KPI45258.1 - 0.005 15.8 0.3 0.006 15.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1552) MCR_D PF02505.9 KPI45258.1 - 0.059 12.9 0.0 0.061 12.8 0.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D zf-CCCH PF00642.19 KPI45259.1 - 9.3e-18 63.4 29.6 2.4e-06 27.0 0.3 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KPI45259.1 - 1.2e-06 28.2 36.3 0.028 14.3 0.1 6.2 6 0 0 6 6 6 5 Zinc finger C-x8-C-x5-C-x3-H type PPR_1 PF12854.2 KPI45259.1 - 2 7.9 5.2 12 5.4 0.0 3.0 3 0 0 3 3 3 0 PPR repeat Aminotran_5 PF00266.14 KPI45261.1 - 2.4e-12 46.2 0.0 1.7e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DPRP PF04244.8 KPI45261.1 - 0.098 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein DegT_DnrJ_EryC1 PF01041.12 KPI45261.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.13 KPI45262.1 - 7.2e-09 34.8 0.0 1.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI45262.1 - 0.0091 15.8 5.3 0.017 15.0 3.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HR1 PF02185.11 KPI45262.1 - 0.33 10.7 3.8 7.9 6.3 0.1 2.8 3 0 0 3 3 3 0 Hr1 repeat LRR_4 PF12799.2 KPI45263.1 - 5.7e-15 54.5 18.3 3.6e-07 29.6 1.9 5.7 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KPI45263.1 - 1.7e-13 50.1 7.6 1.5e-08 34.2 2.7 4.0 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KPI45263.1 - 2.9e-08 32.6 8.1 0.041 13.8 0.3 6.2 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.1 KPI45263.1 - 0.00013 21.6 12.1 0.46 10.7 0.4 5.2 6 0 0 6 6 6 3 Leucine Rich repeat LRR_7 PF13504.1 KPI45263.1 - 0.00045 19.9 11.7 3.9 8.0 0.0 6.1 7 0 0 7 7 7 3 Leucine rich repeat LRR_9 PF14580.1 KPI45263.1 - 0.051 13.1 2.1 3.4 7.1 0.4 2.5 1 1 1 2 2 2 0 Leucine-rich repeat Amidohydro_2 PF04909.9 KPI45264.1 - 2.1e-39 135.7 0.2 2.6e-39 135.4 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase Cyt-b5 PF00173.23 KPI45265.1 - 1.4e-19 69.6 0.2 1.5e-19 69.5 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 KPI45265.1 - 0.0033 17.3 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H BRX PF08381.6 KPI45265.1 - 0.13 11.3 0.5 0.52 9.4 0.3 2.2 1 1 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 adh_short PF00106.20 KPI45266.1 - 1.7e-30 106.1 1.9 2.6e-30 105.5 1.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI45266.1 - 4.4e-15 56.1 0.1 5.9e-15 55.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI45266.1 - 2.6e-12 46.7 0.7 4e-12 46.1 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI45266.1 - 1.4e-05 24.7 0.1 3.1e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KPI45266.1 - 0.0071 16.1 0.2 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KPI45266.1 - 0.12 11.5 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family VMA21 PF09446.5 KPI45268.1 - 9.5e-05 22.2 11.5 0.0028 17.5 6.6 2.1 1 1 1 2 2 2 2 VMA21-like domain RasGEF PF00617.14 KPI45269.1 - 1.2e-41 142.5 0.0 2.5e-41 141.4 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KPI45269.1 - 1.1e-10 41.5 0.0 2.4e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 KPI45269.1 - 8.2e-07 29.5 0.0 1.8e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KPI45269.1 - 6.4e-05 22.3 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Ras family DUF4551 PF15087.1 KPI45269.1 - 0.64 8.3 0.0 0.64 8.3 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4551) MFS_1 PF07690.11 KPI45271.1 - 1.1e-50 172.3 54.2 9.9e-49 165.9 38.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KPI45271.1 - 8.9e-19 67.1 17.7 1.2e-18 66.7 12.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KPI45271.1 - 1.1e-13 50.6 12.0 1.1e-13 50.6 8.3 3.6 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 KPI45271.1 - 4.5e-06 25.3 5.2 4.5e-06 25.3 3.6 3.1 2 1 0 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 KPI45271.1 - 0.0068 14.5 6.7 0.015 13.4 4.7 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector DUF1180 PF06679.7 KPI45271.1 - 0.041 13.7 2.8 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Phage_Gp23 PF10669.4 KPI45271.1 - 4.4 7.4 7.3 0.21 11.6 1.1 1.7 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Glyco_transf_25 PF01755.12 KPI45272.1 - 2.9e-07 30.3 0.1 5.5e-06 26.1 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) 2-Hacid_dh_C PF02826.14 KPI45273.1 - 6e-40 136.2 0.7 5.7e-23 80.9 0.0 2.8 2 1 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 KPI45273.1 - 0.0025 17.7 0.2 0.056 13.4 0.1 2.3 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KPI45273.1 - 0.041 13.7 0.1 0.087 12.6 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 KPI45273.1 - 0.053 13.3 0.4 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 KPI45273.1 - 0.066 12.5 1.4 0.08 12.3 0.2 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 KPI45273.1 - 0.082 12.5 0.3 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KPI45273.1 - 0.092 12.7 0.4 0.24 11.3 0.3 1.7 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 KPI45273.1 - 0.11 12.4 0.4 0.33 10.8 0.3 1.8 1 0 0 1 1 1 0 short chain dehydrogenase Prenyltransf PF01255.14 KPI45274.1 - 0.028 13.5 0.0 3.6 6.6 0.0 3.0 2 1 0 2 2 2 0 Putative undecaprenyl diphosphate synthase PhyH PF05721.8 KPI45275.1 - 5.7e-08 33.0 0.0 9.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) JmjC PF02373.17 KPI45275.1 - 0.17 12.0 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 JmjC domain, hydroxylase Acetyltransf_1 PF00583.19 KPI45276.1 - 3.1e-18 65.5 0.0 4.3e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KPI45276.1 - 1e-08 34.8 0.0 1.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KPI45276.1 - 1.5e-08 34.6 0.0 2.7e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KPI45276.1 - 1.9e-06 27.9 0.0 2.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KPI45276.1 - 4.7e-05 23.3 0.0 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KPI45276.1 - 8.4e-05 22.4 0.0 0.00014 21.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KPI45276.1 - 0.0032 17.4 0.0 0.0052 16.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain SAS4 PF15460.1 KPI45277.1 - 4.3e-29 100.3 5.1 4.3e-29 100.3 3.5 2.7 3 0 0 3 3 3 1 Something about silencing, SAS, complex subunit 4 Mito_fiss_reg PF05308.6 KPI45277.1 - 0.0019 17.5 0.6 0.0019 17.5 0.4 3.4 3 1 0 3 3 3 2 Mitochondrial fission regulator Urb2 PF10441.4 KPI45278.1 - 5.6e-45 153.6 0.3 1.9e-44 151.9 0.0 2.1 2 0 0 2 2 2 1 Urb2/Npa2 family AAA_16 PF13191.1 KPI45279.1 - 2.4e-06 27.6 3.2 3.4e-06 27.1 0.1 2.6 2 1 1 3 3 3 1 AAA ATPase domain NACHT PF05729.7 KPI45279.1 - 2.6e-06 27.1 0.0 5.6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Cutinase PF01083.17 KPI45279.1 - 0.00055 19.7 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Cutinase AAA_22 PF13401.1 KPI45279.1 - 0.0016 18.5 0.0 0.011 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Abhydrolase_6 PF12697.2 KPI45279.1 - 0.0019 18.0 1.0 0.01 15.7 0.3 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KPI45279.1 - 0.0051 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KPI45279.1 - 0.009 15.3 0.0 0.026 13.8 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DAP3 PF10236.4 KPI45279.1 - 0.052 12.4 0.1 0.45 9.3 0.0 2.3 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Arch_ATPase PF01637.13 KPI45279.1 - 0.076 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase Sulfatase PF00884.18 KPI45280.1 - 2.9e-57 194.2 0.1 4.2e-57 193.6 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 KPI45280.1 - 5.9e-17 61.2 4.1 1.2e-16 60.2 1.8 2.2 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 KPI45280.1 - 2.9e-11 43.2 0.7 1.8e-10 40.6 0.5 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KPI45280.1 - 0.00025 21.3 0.1 0.00096 19.4 0.0 2.0 1 1 1 2 2 2 1 C-terminal region of aryl-sulfatase Metalloenzyme PF01676.13 KPI45280.1 - 0.0046 16.3 0.0 0.36 10.1 0.0 2.4 2 1 0 2 2 2 1 Metalloenzyme superfamily DUF229 PF02995.12 KPI45280.1 - 0.0082 14.6 0.0 0.013 13.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Herpes_capsid PF06112.6 KPI45280.1 - 0.024 14.6 0.1 0.043 13.8 0.1 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF1501 PF07394.7 KPI45280.1 - 0.034 12.9 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Ribosomal_L35Ae PF01247.13 KPI45281.1 - 1.5e-45 152.8 0.4 1.7e-45 152.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KPI45281.1 - 6.1e-05 22.8 0.0 0.042 13.7 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Aminotran_1_2 PF00155.16 KPI45282.1 - 6.8e-45 153.5 0.0 7.5e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KPI45282.1 - 0.0019 17.3 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase NIR_SIR_ferr PF03460.12 KPI45282.1 - 0.017 14.7 0.0 6.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain Aminotran_3 PF00202.16 KPI45282.1 - 0.079 11.7 0.0 0.19 10.5 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-III Grp1_Fun34_YaaH PF01184.14 KPI45283.1 - 1.5e-25 89.7 19.6 1.9e-25 89.4 13.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF962 PF06127.6 KPI45285.1 - 1.2e-26 92.3 0.0 2.1e-26 91.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) 2OG-FeII_Oxy PF03171.15 KPI45286.1 - 0.00059 20.0 0.0 0.0022 18.2 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.8 KPI45287.1 - 1.2e-10 41.7 0.0 2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KPI45287.1 - 1.5e-07 30.3 0.0 0.032 12.7 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) Mcp5_PH PF12814.2 KPI45288.1 - 4.5e-45 152.5 0.2 8.8e-45 151.5 0.1 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 KPI45288.1 - 0.00011 22.0 15.7 0.002 17.8 3.8 2.4 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein Lebercilin PF15619.1 KPI45288.1 - 0.0058 16.0 17.3 0.011 15.2 12.0 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.6 KPI45288.1 - 0.56 8.8 10.4 1.1 7.8 7.1 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.5 KPI45288.1 - 0.78 9.8 6.5 6.4 6.8 0.3 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.3 KPI45288.1 - 0.89 9.4 17.8 0.15 11.9 5.1 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 KPI45288.1 - 4.5 6.2 9.0 8.1 5.3 6.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIVA PF05103.8 KPI45288.1 - 7.8 6.5 13.8 6.5 6.8 2.6 2.5 2 0 0 2 2 2 0 DivIVA protein zf-C2H2_4 PF13894.1 KPI45289.1 - 1.5e-05 24.9 19.8 0.01 16.1 0.5 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI45289.1 - 0.0056 16.9 1.7 0.0056 16.9 1.2 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met2 PF12907.2 KPI45289.1 - 0.026 14.5 2.1 0.026 14.5 1.5 2.7 3 0 0 3 3 3 0 Zinc-binding SurA_N_2 PF13623.1 KPI45290.1 - 0.033 14.1 0.2 0.042 13.8 0.2 1.2 1 0 0 1 1 1 0 SurA N-terminal domain Pox_polyA_pol_C PF12629.2 KPI45290.1 - 0.042 13.5 0.7 0.054 13.2 0.5 1.1 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase C-terminal domain Ring_hydroxyl_B PF00866.13 KPI45290.1 - 0.08 12.6 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Ring hydroxylating beta subunit Glyco_hydro_18 PF00704.23 KPI45291.1 - 2.2e-54 185.1 0.0 2.9e-54 184.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 KPI45291.1 - 0.00012 21.8 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) HET PF06985.6 KPI45292.1 - 1.4e-28 99.7 0.3 2.3e-28 99.0 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Dynamin_N PF00350.18 KPI45293.1 - 7.3e-30 103.9 0.6 8.4e-29 100.5 0.1 2.4 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KPI45293.1 - 7.9e-24 83.9 4.8 4.2e-20 71.7 0.2 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KPI45293.1 - 0.00075 19.4 0.1 0.0069 16.3 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 KPI45293.1 - 0.064 13.1 0.3 0.064 13.1 0.2 3.6 3 1 0 3 3 3 0 Dynamin GTPase effector domain Syntaxin_2 PF14523.1 KPI45293.1 - 0.23 11.5 8.9 0.096 12.7 0.2 3.7 4 0 0 4 4 4 0 Syntaxin-like protein PI-PLC-X PF00388.14 KPI45294.1 - 2.8e-57 192.2 0.0 4.2e-57 191.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KPI45294.1 - 1.3e-34 118.7 0.0 2.4e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain ADH_N PF08240.7 KPI45294.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain PHD PF00628.24 KPI45296.1 - 0.006 16.2 2.6 0.011 15.3 1.8 1.4 1 0 0 1 1 1 1 PHD-finger DUF3052 PF11253.3 KPI45296.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) Pkinase PF00069.20 KPI45298.1 - 1.4e-10 40.8 0.0 8.7e-10 38.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain DSBA PF01323.15 KPI45298.1 - 4.4e-07 29.6 1.0 7.3e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 DSBA-like thioredoxin domain AvrE PF11725.3 KPI45298.1 - 0.41 7.6 6.4 0.58 7.1 4.4 1.1 1 0 0 1 1 1 0 Pathogenicity factor Peptidase_M16 PF00675.15 KPI45298.1 - 0.41 10.3 4.7 13 5.5 0.0 2.8 2 1 0 2 2 2 0 Insulinase (Peptidase family M16) SHS2_Rpb7-N PF03876.12 KPI45299.1 - 3.5e-13 49.4 0.0 5.4e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KPI45299.1 - 3.8e-07 30.0 0.0 6.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain G-alpha PF00503.15 KPI45300.1 - 3.4e-19 68.8 0.0 5.1e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit Thioredoxin PF00085.15 KPI45301.1 - 0.0037 16.9 0.0 0.0044 16.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF3807 PF12720.2 KPI45302.1 - 4.1e-28 98.6 6.3 5.8e-28 98.1 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Spore_coat_CotO PF14153.1 KPI45302.1 - 1.1 8.6 7.8 1.6 8.1 5.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO PBP1_TM PF14812.1 KPI45302.1 - 1.8 8.8 8.0 3.7 7.9 5.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1682 PF07946.9 KPI45302.1 - 6.9 5.4 8.3 9 5.0 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TauD PF02668.11 KPI45303.1 - 6.8e-27 94.7 0.0 9.1e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_4 PF01565.18 KPI45304.1 - 3e-22 78.6 3.4 4.2e-22 78.1 2.4 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KPI45304.1 - 2.3e-09 37.0 0.0 4.5e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like HET PF06985.6 KPI45306.1 - 1.3e-34 119.3 1.0 2.9e-34 118.1 0.7 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Malic_M PF03949.10 KPI45307.1 - 3.5e-85 285.6 0.0 4.3e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KPI45307.1 - 5.9e-58 195.4 0.0 9.7e-58 194.7 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF187 PF02638.10 KPI45307.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 AA_permease_2 PF13520.1 KPI45308.1 - 2.7e-46 158.0 46.9 2e-43 148.5 26.4 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 KPI45308.1 - 9.6e-26 90.1 34.9 9.6e-26 90.1 24.2 1.9 2 0 0 2 2 2 1 Amino acid permease dCMP_cyt_deam_1 PF00383.17 KPI45309.1 - 6.4e-23 80.3 0.1 8.6e-23 79.9 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KPI45309.1 - 3.4e-05 23.7 1.6 0.21 11.4 0.5 2.3 1 1 1 2 2 2 2 Bd3614-like deaminase APOBEC_N PF08210.6 KPI45309.1 - 0.0044 16.6 0.1 0.051 13.1 0.0 2.0 1 1 0 2 2 2 1 APOBEC-like N-terminal domain XOO_2897-deam PF14440.1 KPI45309.1 - 0.011 15.4 0.1 0.019 14.6 0.0 1.5 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase MFS_1 PF07690.11 KPI45310.1 - 1.3e-38 132.6 28.2 1.8e-38 132.1 19.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Complex1_49kDa PF00346.14 KPI45311.1 - 7.4e-129 428.5 0.0 1.2e-128 427.8 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Pkinase PF00069.20 KPI45311.1 - 5.1e-52 176.5 0.4 4.3e-28 98.1 0.2 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KPI45311.1 - 1.8e-25 89.4 0.0 1.4e-19 70.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase DUF1752 PF08550.5 KPI45312.1 - 6.8e-06 25.5 6.8 1.2e-05 24.7 4.7 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Ovate PF04844.8 KPI45313.1 - 0.12 12.1 0.1 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Transcriptional repressor, ovate Glyco_transf_34 PF05637.7 KPI45316.1 - 6.5e-64 215.6 0.4 8.8e-64 215.2 0.3 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family LMBR1 PF04791.11 KPI45317.1 - 6.8e-17 61.2 0.6 6.8e-17 61.2 0.4 2.2 1 1 1 2 2 2 2 LMBR1-like membrane protein stn_TNFRSF12A PF12191.3 KPI45317.1 - 0.4 10.7 3.1 1.1 9.2 0.2 3.0 3 0 0 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF2457 PF10446.4 KPI45318.1 - 7.8e-125 417.1 41.1 7.8e-125 417.1 28.5 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2457) ubiquitin PF00240.18 KPI45319.1 - 2e-24 84.7 0.1 2.2e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KPI45319.1 - 7.1e-16 57.6 0.1 7.8e-16 57.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KPI45319.1 - 0.00024 21.2 0.0 0.00073 19.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 KPI45319.1 - 0.066 13.1 0.0 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF3738 PF12543.3 KPI45320.1 - 0.0078 15.7 1.2 0.0078 15.7 0.8 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3738) DUF1087 PF06465.8 KPI45321.1 - 0.16 11.9 2.7 0.43 10.5 1.9 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) Zip PF02535.17 KPI45321.1 - 0.73 8.7 5.9 1.2 8.0 4.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PI-PLC-X PF00388.14 KPI45322.1 - 1.3e-44 151.1 0.0 2.1e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KPI45322.1 - 7.6e-31 106.5 0.0 1.6e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain FerI PF08151.7 KPI45322.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 FerI (NUC094) domain Kinesin PF00225.18 KPI45323.1 - 7.6e-111 370.0 0.4 1.7e-110 368.8 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain FHA PF00498.21 KPI45323.1 - 1.3e-05 25.1 0.0 0.00012 22.0 0.0 2.5 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.3 KPI45323.1 - 0.0014 18.5 1.4 0.0014 18.5 1.0 2.2 2 0 0 2 2 2 1 Kinesin protein 1B AAA_22 PF13401.1 KPI45323.1 - 0.088 12.9 0.0 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain COPR5 PF15340.1 KPI45323.1 - 1.5 9.1 6.6 23 5.3 0.0 3.2 2 1 1 3 3 3 0 Cooperator of PRMT5 family Sybindin PF04099.7 KPI45324.1 - 4.3e-25 88.0 0.0 5.2e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KPI45324.1 - 0.0082 16.0 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region MMS19_N PF14500.1 KPI45325.1 - 1.5e-89 299.7 0.0 4.2e-89 298.2 0.0 1.7 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 KPI45325.1 - 0.00023 21.3 4.9 0.19 12.0 0.1 4.2 4 1 0 4 4 4 2 HEAT repeats Adaptin_N PF01602.15 KPI45325.1 - 0.0045 15.3 0.7 0.25 9.6 0.1 2.9 3 0 0 3 3 3 1 Adaptin N terminal region IU_nuc_hydro PF01156.14 KPI45326.1 - 3.2e-77 259.8 0.0 3.7e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase 3Beta_HSD PF01073.14 KPI45327.1 - 6.9e-44 149.6 0.0 3.2e-39 134.3 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KPI45327.1 - 7.1e-25 87.8 0.0 1.2e-21 77.3 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KPI45327.1 - 1.2e-14 53.8 0.1 3.5e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 KPI45327.1 - 2.3e-11 43.0 0.7 7e-11 41.5 0.2 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KPI45327.1 - 5e-07 29.9 0.1 6.2e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 KPI45327.1 - 0.00013 21.9 1.3 0.044 13.7 0.2 2.9 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KPI45327.1 - 0.00034 20.3 0.3 0.0087 15.7 0.2 2.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KPI45327.1 - 0.00035 19.5 0.1 0.019 13.8 0.1 2.7 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KPI45327.1 - 0.01 14.8 0.0 0.028 13.3 0.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase Gly_transf_sug PF04488.10 KPI45328.1 - 2.2e-06 27.9 0.0 4.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KPI45328.1 - 0.03 12.8 0.0 0.44 8.9 0.0 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain ELMO_CED12 PF04727.8 KPI45329.1 - 7.8e-40 136.1 0.1 1.2e-39 135.5 0.1 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 KPI45329.1 - 9.5e-06 25.4 0.0 0.00037 20.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) ADH_N PF08240.7 KPI45330.1 - 3.8e-24 84.5 3.5 5.9e-24 83.9 2.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI45330.1 - 6.7e-07 28.9 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI45330.1 - 0.0012 19.7 0.0 0.002 19.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CAP-ZIP_m PF15255.1 KPI45330.1 - 0.081 12.8 0.1 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 WASH complex subunit CAP-Z interacting, central region SprA-related PF12118.3 KPI45331.1 - 0.95 8.7 12.0 1.3 8.2 8.3 1.2 1 0 0 1 1 1 0 SprA-related family Presenilin PF01080.12 KPI45331.1 - 7 5.3 12.8 9.3 4.9 8.9 1.3 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.6 KPI45331.1 - 7.2 4.8 13.6 8.6 4.5 9.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 FAD_binding_4 PF01565.18 KPI45332.1 - 1.6e-22 79.5 2.5 2.6e-22 78.7 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KPI45332.1 - 1.2e-07 31.4 0.2 2.4e-07 30.5 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KPI45332.1 - 0.049 12.7 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Nbl1_Borealin_N PF10444.4 KPI45336.1 - 1.2e-19 69.3 3.5 2e-19 68.6 2.4 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal ZYG-11_interact PF05884.7 KPI45336.1 - 0.038 13.0 0.0 0.086 11.9 0.0 1.5 1 0 0 1 1 1 0 Interactor of ZYG-11 zf-C2H2_6 PF13912.1 KPI45337.1 - 0.001 18.8 2.7 0.14 12.1 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI45337.1 - 0.046 14.0 24.5 0.65 10.4 0.3 5.1 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI45337.1 - 0.12 12.7 18.2 0.14 12.5 0.1 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.2 KPI45337.1 - 0.2 11.9 1.9 7.1 6.9 0.4 3.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type OSTMP1 PF09777.4 KPI45337.1 - 0.29 10.2 8.0 3 6.9 5.5 2.1 1 1 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor DUF4611 PF15387.1 KPI45337.1 - 4.6 7.4 9.3 6.9 6.8 5.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) Zip PF02535.17 KPI45338.1 - 1.5e-16 60.2 1.4 1.9e-16 59.9 0.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter HLH PF00010.21 KPI45339.1 - 5.4e-14 51.6 2.1 6.1e-14 51.4 0.3 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Prefoldin_2 PF01920.15 KPI45339.1 - 0.0077 15.9 2.8 0.015 15.0 1.9 1.5 1 0 0 1 1 1 1 Prefoldin subunit Nup54 PF13874.1 KPI45339.1 - 0.0082 15.8 2.3 0.016 14.8 1.6 1.4 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 FlaC_arch PF05377.6 KPI45339.1 - 0.012 15.5 2.2 0.016 15.1 0.6 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Macoilin PF09726.4 KPI45339.1 - 0.023 13.0 5.1 0.028 12.7 3.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Atg14 PF10186.4 KPI45339.1 - 0.082 11.8 6.2 0.15 10.9 4.3 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Cluap1 PF10234.4 KPI45339.1 - 0.092 11.9 3.4 0.13 11.4 2.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 APG6 PF04111.7 KPI45339.1 - 0.096 11.7 7.0 0.14 11.2 4.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FlxA PF14282.1 KPI45339.1 - 0.1 12.5 10.7 0.092 12.7 6.0 1.9 2 1 0 2 2 2 0 FlxA-like protein IncA PF04156.9 KPI45339.1 - 8.3 5.9 9.7 7 6.2 5.6 1.5 1 1 0 1 1 1 0 IncA protein LSM PF01423.17 KPI45340.1 - 4e-13 48.7 0.6 7.2e-13 47.8 0.4 1.4 1 0 0 1 1 1 1 LSM domain PCI PF01399.22 KPI45341.1 - 2.5e-09 37.4 0.0 2.5e-09 37.4 0.0 3.2 3 0 0 3 3 3 1 PCI domain VWA_3 PF13768.1 KPI45342.1 - 0.0024 17.5 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Aminotran_1_2 PF00155.16 KPI45343.1 - 5.3e-48 163.8 0.0 6.4e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Kdo_hydroxy PF11004.3 KPI45343.1 - 0.0057 15.7 0.0 0.0094 14.9 0.0 1.2 1 0 0 1 1 1 1 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase DUF885 PF05960.6 KPI45343.1 - 0.013 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Sec1 PF00995.18 KPI45344.1 - 1.4e-109 367.3 0.0 4.8e-103 345.7 0.0 2.0 1 1 1 2 2 2 2 Sec1 family Pkinase PF00069.20 KPI45347.1 - 1.5e-50 171.8 0.5 3e-49 167.5 0.3 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI45347.1 - 2.3e-15 56.3 0.1 2.1e-14 53.2 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KPI45347.1 - 7e-07 29.2 0.0 0.0001 22.1 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KPI45347.1 - 0.0022 17.5 0.1 0.0047 16.5 0.1 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KPI45347.1 - 0.028 13.4 0.2 0.045 12.7 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAD_binding_6 PF08030.7 KPI45348.1 - 2.6e-33 115.1 0.0 4.6e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KPI45348.1 - 1.1e-21 76.6 0.0 2.3e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KPI45348.1 - 2.9e-16 59.7 5.9 2.9e-16 59.7 4.1 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KPI45348.1 - 2.2e-05 24.4 0.0 6.2e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KPI45348.1 - 0.045 14.3 0.0 0.54 10.8 0.0 2.7 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain Nnf1 PF03980.9 KPI45349.1 - 1.8e-25 89.0 2.8 2.6e-25 88.5 2.0 1.2 1 0 0 1 1 1 1 Nnf1 DUF4613 PF15390.1 KPI45349.1 - 0.015 13.5 0.2 0.017 13.3 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) UPF0242 PF06785.6 KPI45349.1 - 0.05 12.2 1.6 0.14 10.7 0.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) Syntaxin-6_N PF09177.6 KPI45349.1 - 0.078 13.3 0.3 0.21 12.0 0.2 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal BLOC1_2 PF10046.4 KPI45349.1 - 0.15 12.2 2.2 0.17 12.0 0.5 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4635 PF15466.1 KPI45349.1 - 0.17 11.1 1.3 0.3 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) FliT PF05400.8 KPI45349.1 - 0.89 10.0 7.1 7.4 7.0 4.9 2.3 1 1 0 1 1 1 0 Flagellar protein FliT zf-B_box PF00643.19 KPI45350.1 - 0.0036 17.1 1.7 0.0055 16.5 1.2 1.2 1 0 0 1 1 1 1 B-box zinc finger zf-C3HC4_2 PF13923.1 KPI45350.1 - 0.035 14.1 4.1 0.057 13.4 2.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MFS_1 PF07690.11 KPI45351.1 - 1.2e-25 89.9 12.1 1.6e-25 89.6 8.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-rbx1 PF12678.2 KPI45352.1 - 2.7e-12 46.6 1.1 4.9e-12 45.7 0.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KPI45352.1 - 3.9e-10 39.3 6.2 1.1e-09 37.9 4.3 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KPI45352.1 - 1.6e-06 27.6 3.6 2.8e-06 26.8 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RCR PF12273.3 KPI45352.1 - 1.1e-05 26.0 15.1 9.6e-05 22.9 10.5 2.7 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red zf-RING_5 PF14634.1 KPI45352.1 - 4.3e-05 23.1 4.0 0.00013 21.6 2.9 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KPI45352.1 - 5e-05 23.2 2.4 5e-05 23.2 1.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KPI45352.1 - 5.5e-05 22.7 7.4 0.00054 19.5 5.1 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KPI45352.1 - 0.0001 22.0 0.9 0.0003 20.5 0.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KPI45352.1 - 0.00067 19.3 4.2 0.0016 18.1 2.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger LRRC37AB_C PF14914.1 KPI45352.1 - 0.33 10.3 0.5 0.72 9.2 0.3 1.5 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain zf-C3HC4_4 PF15227.1 KPI45352.1 - 1.6 8.6 6.2 0.17 11.8 1.0 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RTC4 PF14474.1 KPI45353.1 - 5.5e-25 87.7 0.0 9e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain HeLo PF14479.1 KPI45354.1 - 1.5e-07 31.4 0.1 2.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation DUF1993 PF09351.5 KPI45355.1 - 0.51 10.2 5.2 0.27 11.1 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) MMR_HSR1 PF01926.18 KPI45356.1 - 5.1e-09 36.0 0.0 9e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KPI45356.1 - 1.5e-07 30.7 0.0 2.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 KPI45356.1 - 1.5e-05 25.5 0.0 2.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 KPI45356.1 - 0.0013 17.7 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_18 PF13238.1 KPI45356.1 - 0.0014 18.8 0.0 0.0035 17.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 KPI45356.1 - 0.0018 19.0 0.2 0.0038 18.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KPI45356.1 - 0.0018 17.7 0.1 0.8 9.1 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Ras PF00071.17 KPI45356.1 - 0.0022 17.3 0.0 0.0042 16.4 0.0 1.5 1 0 0 1 1 1 1 Ras family MobB PF03205.9 KPI45356.1 - 0.004 16.8 0.1 0.0091 15.7 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KPI45356.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KPI45356.1 - 0.012 15.7 0.0 0.034 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 KPI45356.1 - 0.016 14.6 0.3 0.42 10.0 0.2 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 KPI45356.1 - 0.021 15.1 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 KPI45356.1 - 0.023 14.7 0.2 0.061 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 KPI45356.1 - 0.026 13.9 0.2 0.15 11.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KPI45356.1 - 0.039 13.4 0.7 0.1 12.1 0.5 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.5 KPI45356.1 - 0.051 12.7 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RNA_helicase PF00910.17 KPI45356.1 - 0.093 12.9 0.1 0.28 11.3 0.0 1.9 2 0 0 2 2 1 0 RNA helicase MCM PF00493.18 KPI45356.1 - 0.11 11.2 0.1 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family ArgK PF03308.11 KPI45356.1 - 0.11 11.2 0.3 0.23 10.1 0.2 1.5 1 0 0 1 1 1 0 ArgK protein AAA_28 PF13521.1 KPI45356.1 - 0.13 12.2 2.1 0.2 11.5 0.6 2.0 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KPI45356.1 - 0.13 11.1 0.6 0.24 10.2 0.4 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 KPI45356.1 - 0.17 11.7 0.0 0.61 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KPI45356.1 - 0.18 11.6 0.9 4.5 7.0 0.5 2.4 1 1 1 2 2 2 0 Dynamin family DUF87 PF01935.12 KPI45356.1 - 0.28 10.9 1.0 0.51 10.1 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 Ubiq_cyt_C_chap PF03981.7 KPI45357.1 - 9.8e-30 103.2 0.2 1.8e-29 102.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone HATPase_c_3 PF13589.1 KPI45359.1 - 0.066 12.8 0.7 0.67 9.6 0.0 2.6 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Malic_M PF03949.10 KPI45360.1 - 7.4e-68 228.8 0.0 5.5e-67 225.9 0.0 2.0 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KPI45360.1 - 6.7e-63 211.5 0.0 1.1e-62 210.8 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain KdpC PF02669.10 KPI45360.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Baculo_PEP_C PF04513.7 KPI45362.1 - 0.0035 17.1 1.0 0.0071 16.1 0.1 1.9 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_S41 PF03572.13 KPI45362.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S41 COMP PF11598.3 KPI45364.1 - 3.9 7.6 4.8 22 5.2 1.3 3.0 2 1 0 2 2 2 0 Cartilage oligomeric matrix protein Sds3 PF08598.6 KPI45365.1 - 1.1e-24 87.0 0.8 1.1e-24 87.0 0.6 4.0 2 2 0 2 2 2 1 Sds3-like Linker_histone PF00538.14 KPI45366.1 - 1.2e-25 89.4 0.8 1.2e-25 89.4 0.6 2.0 2 0 0 2 2 2 1 linker histone H1 and H5 family Thioredoxin PF00085.15 KPI45367.1 - 2.9e-31 107.2 0.1 3e-25 87.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 KPI45367.1 - 1.4e-11 44.5 0.0 0.00011 22.0 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KPI45367.1 - 8.9e-09 35.5 0.5 0.0025 18.0 0.2 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KPI45367.1 - 1.6e-06 28.0 0.2 0.0067 16.5 0.0 3.9 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_3 PF13192.1 KPI45367.1 - 0.00037 20.2 0.1 0.93 9.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain TraF PF13728.1 KPI45367.1 - 0.0023 17.4 4.2 0.11 11.9 0.0 3.0 3 0 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_7 PF13899.1 KPI45367.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like ERp29_N PF07912.8 KPI45367.1 - 0.035 14.0 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 ERp29, N-terminal domain HyaE PF07449.6 KPI45367.1 - 0.069 13.0 0.0 0.33 10.8 0.0 2.2 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE EutB PF06751.6 KPI45367.1 - 0.17 10.1 0.0 0.24 9.6 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) Transpos_assoc PF13963.1 KPI45368.1 - 0.0077 16.2 1.2 0.019 14.9 0.9 1.6 1 0 0 1 1 1 1 Transposase-associated domain BTB PF00651.26 KPI45368.1 - 0.011 15.7 0.0 0.23 11.4 0.0 2.6 2 0 0 2 2 2 0 BTB/POZ domain CBFB_NFYA PF02045.10 KPI45369.1 - 4.7e-31 107.1 4.1 8.5e-31 106.2 2.9 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 KPI45369.1 - 0.027 13.4 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein Pal1 PF08316.6 KPI45370.1 - 2.1e-06 28.2 0.1 5.1e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 Pal1 cell morphology protein PEP_mutase PF13714.1 KPI45371.1 - 8.8e-50 169.1 0.1 1.1e-49 168.8 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase EF-hand_7 PF13499.1 KPI45372.1 - 1.1e-09 38.2 0.2 2.5e-06 27.5 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KPI45372.1 - 4.1e-09 35.5 0.0 2.6e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KPI45372.1 - 2.3e-08 32.7 0.0 3.5e-05 22.8 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 KPI45372.1 - 2.1e-07 29.9 1.1 1.8e-05 23.8 0.2 2.8 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 KPI45372.1 - 0.00072 19.1 0.0 0.23 11.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 KPI45372.1 - 0.008 16.0 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain FAM75 PF14650.1 KPI45372.1 - 0.42 9.9 6.5 0.65 9.3 4.5 1.2 1 0 0 1 1 1 0 FAM75 family PX PF00787.19 KPI45373.1 - 9.1e-20 70.5 0.0 1.4e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 PX domain Rotavirus_VP1 PF12289.3 KPI45373.1 - 0.0099 15.4 0.0 0.049 13.2 0.0 2.0 2 0 0 2 2 2 1 Rotavirus VP1 structural protein AA_permease_2 PF13520.1 KPI45374.1 - 1e-31 109.9 33.1 1.2e-31 109.6 23.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI45374.1 - 7.4e-13 47.6 23.9 9.8e-13 47.2 16.6 1.1 1 0 0 1 1 1 1 Amino acid permease Glycos_transf_1 PF00534.15 KPI45376.1 - 4.9e-37 126.9 0.0 1e-36 125.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KPI45376.1 - 9.6e-18 64.6 0.0 2.4e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KPI45376.1 - 3.3e-14 53.3 0.1 1.1e-13 51.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KPI45376.1 - 2.2e-10 40.6 0.0 4.6e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KPI45376.1 - 1.4e-06 28.1 0.0 2.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.1 KPI45376.1 - 0.0062 16.3 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like HTH_17 PF12728.2 KPI45376.1 - 0.035 14.3 0.0 10 6.4 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain CoA_binding_2 PF13380.1 KPI45376.1 - 0.12 12.5 0.0 27 4.9 0.0 3.0 2 1 0 2 2 2 0 CoA binding domain Esterase PF00756.15 KPI45377.1 - 4.7e-46 157.2 0.0 6.2e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 KPI45377.1 - 4.1e-07 29.4 0.0 3.7e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 KPI45377.1 - 9.9e-06 25.3 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KPI45377.1 - 2.9e-05 23.3 0.4 6.1e-05 22.3 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 KPI45377.1 - 8.1e-05 21.2 0.0 0.00011 20.8 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 KPI45377.1 - 0.0004 20.3 0.0 0.00056 19.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KPI45377.1 - 0.0025 16.7 0.0 0.0038 16.1 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.20 KPI45377.1 - 0.0058 16.2 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.11 KPI45377.1 - 0.0089 15.4 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase PGAP1 PF07819.8 KPI45377.1 - 0.011 15.3 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 KPI45377.1 - 0.057 12.9 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1772 PF08592.6 KPI45378.1 - 6.8e-16 58.2 1.2 1.1e-15 57.5 0.8 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Methyltransf_11 PF08241.7 KPI45379.1 - 5e-12 46.1 0.0 1.3e-11 44.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI45379.1 - 1.6e-09 37.6 0.0 2.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI45379.1 - 3.7e-09 36.9 0.0 8.7e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI45379.1 - 6e-08 32.4 0.0 1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI45379.1 - 1.3e-07 31.9 0.0 2.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI45379.1 - 3.8e-07 30.6 0.0 7.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI45379.1 - 2e-05 24.5 0.2 8.1e-05 22.6 0.1 2.0 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KPI45379.1 - 0.026 13.8 0.0 0.39 10.0 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 KPI45379.1 - 0.057 12.4 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Vps8 PF12816.2 KPI45380.1 - 6.8e-60 201.6 0.1 1.4e-59 200.6 0.0 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 KPI45380.1 - 6.5e-05 22.5 0.3 0.027 14.0 0.0 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS RNase_T PF00929.19 KPI45381.1 - 1.1e-21 77.8 0.0 2.4e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Exonuclease A_deaminase PF00962.17 KPI45382.1 - 1.5e-105 352.8 0.1 2.3e-105 352.1 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Fungal_trans PF04082.13 KPI45383.1 - 4.6e-07 28.9 0.6 1.1e-06 27.7 0.0 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain p450 PF00067.17 KPI45384.1 - 2.6e-68 230.6 0.0 3.2e-68 230.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Yip1 PF04893.12 KPI45385.1 - 0.005 16.3 0.3 0.0062 16.0 0.2 1.1 1 0 0 1 1 1 1 Yip1 domain EIIBC-GUT_C PF07663.6 KPI45385.1 - 0.047 13.8 0.3 0.084 13.0 0.2 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II C-terminus RAMP PF04901.8 KPI45385.1 - 0.15 11.8 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Receptor activity modifying family TM2 PF05154.11 KPI45385.1 - 9.1 6.5 7.9 0.92 9.7 1.5 2.3 2 1 0 2 2 2 0 TM2 domain Ribonuc_L-PSP PF01042.16 KPI45387.1 - 5.1e-17 61.7 0.0 6.6e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP NOGCT PF08155.6 KPI45387.1 - 0.12 12.0 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 NOGCT (NUC087) domain adh_short PF00106.20 KPI45388.1 - 3e-09 37.0 0.4 4.3e-09 36.5 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KPI45388.1 - 5.2e-05 22.9 0.0 7.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI45388.1 - 0.089 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding UPF0183 PF03676.9 KPI45389.1 - 1.3e-38 132.6 0.0 8.5e-28 97.0 0.0 3.2 2 2 0 2 2 2 2 Uncharacterised protein family (UPF0183) CorA PF01544.13 KPI45390.1 - 0.00096 18.2 11.1 0.016 14.2 7.7 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Glycos_transf_1 PF00534.15 KPI45391.1 - 3.6e-12 46.0 0.0 6.9e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.3 KPI45391.1 - 0.00013 21.6 0.0 0.00044 19.8 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) Glyco_trans_1_4 PF13692.1 KPI45391.1 - 0.00017 21.7 0.0 0.0005 20.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 ETAA1 PF15350.1 KPI45391.1 - 0.26 9.2 0.5 0.41 8.6 0.4 1.1 1 0 0 1 1 1 0 Ewing's tumour-associated antigen 1 homologue Abhydrolase_6 PF12697.2 KPI45393.1 - 1.1e-12 48.3 0.1 1.3e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI45393.1 - 4.3e-09 36.2 0.0 4.7e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KPI45393.1 - 0.019 14.5 0.1 0.052 13.1 0.1 1.6 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_2 PF02230.11 KPI45393.1 - 0.029 13.7 0.8 0.58 9.5 0.1 2.1 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.15 KPI45393.1 - 0.038 14.2 0.0 0.049 13.8 0.0 1.3 1 1 0 1 1 1 0 Thioesterase domain DUF2305 PF10230.4 KPI45393.1 - 0.069 12.5 0.1 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF2424 PF10340.4 KPI45393.1 - 0.075 11.6 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) GTP_EFTU PF00009.22 KPI45394.1 - 4.5e-44 150.1 0.0 8.7e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KPI45394.1 - 1.3e-20 73.3 0.0 3.4e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 KPI45394.1 - 1.8e-05 24.6 0.1 4.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 KPI45394.1 - 0.0012 18.8 0.1 0.0031 17.5 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 G-alpha PF00503.15 KPI45394.1 - 0.03 13.0 0.8 0.057 12.0 0.5 1.5 1 1 0 1 1 1 0 G-protein alpha subunit RR_TM4-6 PF06459.7 KPI45394.1 - 9.4 6.0 7.5 16 5.2 5.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NAD_Gly3P_dh_N PF01210.18 KPI45395.1 - 2.1e-47 160.7 0.1 7.9e-47 158.8 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KPI45395.1 - 6.7e-43 145.9 0.2 1e-42 145.3 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus RE_LlaMI PF09562.5 KPI45397.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.5 2 0 0 2 2 2 0 LlaMI restriction endonuclease MFS_1 PF07690.11 KPI45398.1 - 4.5e-27 94.6 25.2 4.5e-27 94.6 17.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NMT PF01233.14 KPI45399.1 - 1.5e-73 245.7 0.0 2.5e-73 245.0 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 KPI45399.1 - 6.8e-72 240.8 0.0 1e-71 240.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 KPI45399.1 - 0.00014 21.6 0.1 0.0077 16.0 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain EF-hand_8 PF13833.1 KPI45399.1 - 0.0018 17.8 0.0 0.0062 16.1 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair FR47 PF08445.5 KPI45399.1 - 0.11 12.2 0.0 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_3 PF13302.1 KPI45399.1 - 0.13 12.4 0.2 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_transf_90 PF05686.7 KPI45400.1 - 1.2e-14 53.8 0.0 1e-13 50.7 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 90 Mgm101p PF06420.7 KPI45400.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 AA_permease_2 PF13520.1 KPI45401.1 - 8.8e-38 129.9 12.1 3.3e-20 72.0 1.5 2.8 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 KPI45401.1 - 0.00061 18.2 6.7 0.00061 18.2 4.7 2.6 1 1 1 2 2 2 1 Amino acid permease DUF4231 PF14015.1 KPI45401.1 - 8.5 6.4 12.1 0.28 11.1 0.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) MFS_1 PF07690.11 KPI45402.1 - 1e-31 109.9 14.8 1e-31 109.9 10.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DPBB_1 PF03330.13 KPI45403.1 - 2.5e-10 40.1 0.0 4.3e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KPI45403.1 - 0.073 12.7 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Barwin family Adaptin_N PF01602.15 KPI45404.1 - 1.4e-83 280.9 0.4 1.9e-83 280.5 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region BLVR PF06375.6 KPI45404.1 - 1.1e-05 25.3 0.1 1.1e-05 25.3 0.1 3.1 2 1 0 2 2 2 1 Bovine leukaemia virus receptor (BLVR) Cnd1 PF12717.2 KPI45404.1 - 0.00013 21.8 0.5 0.13 12.1 0.0 2.9 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KPI45404.1 - 0.0055 16.6 8.0 1.6 8.9 0.0 5.6 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 KPI45404.1 - 0.014 15.8 6.2 3.3 8.3 0.0 4.7 5 0 0 5 5 5 0 HEAT-like repeat RTA1 PF04479.8 KPI45405.1 - 3.9e-59 199.8 7.8 5.2e-59 199.4 5.4 1.1 1 0 0 1 1 1 1 RTA1 like protein Kei1 PF08552.6 KPI45405.1 - 0.008 15.8 1.5 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 Caveolin PF01146.12 KPI45405.1 - 0.039 13.5 1.1 0.039 13.5 0.8 2.1 2 0 0 2 2 2 0 Caveolin PalH PF08733.5 KPI45405.1 - 0.35 9.6 6.1 0.057 12.2 1.4 1.7 2 1 0 2 2 2 0 PalH/RIM21 DUF2678 PF10856.3 KPI45405.1 - 0.41 10.3 5.2 0.42 10.3 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2678) MFS_1 PF07690.11 KPI45407.1 - 6.1e-19 67.9 21.7 6.1e-19 67.9 15.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily ArfGap PF01412.13 KPI45408.1 - 5.5e-33 113.2 2.2 8.4e-33 112.6 0.0 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 KPI45408.1 - 1.3e-11 44.5 0.2 3.7e-11 43.1 0.1 1.8 1 0 0 1 1 1 1 PH domain Prenyltrans PF00432.16 KPI45409.1 - 4.9e-53 176.3 5.7 5.1e-12 45.1 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KPI45409.1 - 6.8e-33 113.4 0.0 2.1e-13 50.6 0.0 3.4 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KPI45409.1 - 3.2e-11 43.1 0.0 0.00059 19.8 0.0 3.2 3 0 0 3 3 3 2 Prenyltransferase-like ABC2_membrane PF01061.19 KPI45410.1 - 1.5e-35 122.3 23.7 2.4e-35 121.5 16.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 KPI45410.1 - 7.4e-06 25.2 30.8 7.4e-06 25.2 21.3 2.2 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 KPI45410.1 - 0.0047 15.8 10.2 0.0047 15.8 7.0 2.2 1 1 1 2 2 2 2 ABC-2 family transporter protein DUF4215 PF13948.1 KPI45411.1 - 0.06 13.5 2.5 0.17 12.1 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4215) DUF4448 PF14610.1 KPI45411.1 - 0.083 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Cation_efflux PF01545.16 KPI45413.1 - 5.6e-25 87.9 5.1 4.4e-24 85.0 3.6 1.9 1 1 0 1 1 1 1 Cation efflux family MFS_1 PF07690.11 KPI45414.1 - 4.4e-37 127.6 32.0 6.4e-37 127.0 22.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI45414.1 - 4.2e-08 32.2 10.1 4.2e-08 32.2 7.0 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KPI45414.1 - 6e-05 21.4 4.7 9.4e-05 20.7 3.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TFIIS_C PF01096.13 KPI45415.1 - 1.3e-12 47.0 2.4 1.3e-12 47.0 1.7 2.9 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KPI45415.1 - 0.00026 20.6 3.1 0.00026 20.6 2.2 2.6 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Churchill PF06573.6 KPI45415.1 - 0.0028 17.6 5.3 0.039 13.9 0.1 2.4 2 1 0 2 2 2 1 Churchill protein Baculo_LEF5_C PF11792.3 KPI45415.1 - 0.0031 16.8 3.6 1.1 8.6 0.3 3.4 3 1 0 3 3 3 1 Baculoviridae late expression factor 5 C-terminal domain Lar_restr_allev PF14354.1 KPI45415.1 - 0.0076 16.5 6.3 0.075 13.3 0.3 2.2 2 0 0 2 2 2 1 Restriction alleviation protein Lar Ogr_Delta PF04606.7 KPI45415.1 - 0.014 15.0 3.2 0.014 15.0 2.2 3.1 2 2 0 2 2 1 0 Ogr/Delta-like zinc finger Rpr2 PF04032.11 KPI45415.1 - 0.016 15.0 7.5 0.92 9.4 0.0 2.6 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain A2L_zn_ribbon PF08792.5 KPI45415.1 - 0.032 13.7 8.2 1.8 8.1 0.1 3.4 3 0 0 3 3 3 0 A2L zinc ribbon domain DUF2387 PF09526.5 KPI45415.1 - 0.16 11.8 0.4 0.16 11.8 0.3 2.5 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-ribbon_3 PF13248.1 KPI45415.1 - 0.32 10.2 12.9 3.6 6.9 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-B_box PF00643.19 KPI45415.1 - 0.39 10.6 11.5 9.4 6.2 0.1 4.0 4 0 0 4 4 4 0 B-box zinc finger GFA PF04828.9 KPI45415.1 - 0.48 10.4 0.0 0.48 10.4 0.0 2.7 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Cytochrome_C554 PF13435.1 KPI45415.1 - 0.85 9.6 8.5 0.13 12.3 2.9 1.8 1 1 1 2 2 2 0 Cytochrome c554 and c-prime C1_4 PF07975.7 KPI45415.1 - 0.9 9.5 8.6 5.7 7.0 1.2 2.8 2 2 0 2 2 2 0 TFIIH C1-like domain PHF5 PF03660.9 KPI45415.1 - 1.3 9.0 6.9 0.2 11.7 0.4 2.5 1 1 1 2 2 2 0 PHF5-like protein DUF3268 PF11672.3 KPI45415.1 - 1.7 8.7 6.5 7 6.7 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) Zn_ribbon_recom PF13408.1 KPI45415.1 - 2 8.7 10.2 4.5 7.6 0.8 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DZR PF12773.2 KPI45415.1 - 2.1 8.2 13.6 1.7e+03 -1.1 9.4 3.2 1 1 0 1 1 1 0 Double zinc ribbon Paired_CXXCH_1 PF09699.5 KPI45415.1 - 2.3 7.7 10.4 6.2 6.4 0.1 3.3 4 0 0 4 4 4 0 Doubled CXXCH motif (Paired_CXXCH_1) Zn-ribbon_8 PF09723.5 KPI45415.1 - 3.6 7.6 12.8 7.7 6.5 0.1 3.9 4 0 0 4 4 4 0 Zinc ribbon domain zf-UBP PF02148.14 KPI45415.1 - 4.5 7.4 8.0 3 8.0 0.3 2.6 2 1 1 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C4_Topoisom PF01396.14 KPI45415.1 - 5 6.7 7.0 14 5.2 0.8 3.0 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-P11 PF03854.9 KPI45415.1 - 5.4 6.5 11.0 4.2 6.9 0.2 3.4 4 0 0 4 4 3 0 P-11 zinc finger FYVE PF01363.16 KPI45415.1 - 7.5 6.5 8.9 2.6e+02 1.5 6.1 2.7 1 1 0 1 1 1 0 FYVE zinc finger Kinesin PF00225.18 KPI45416.1 - 8.1e-74 248.3 0.1 9.3e-69 231.6 0.0 3.1 2 1 1 3 3 3 2 Kinesin motor domain DUF4407 PF14362.1 KPI45416.1 - 0.024 13.6 16.2 0.098 11.5 2.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) IncA PF04156.9 KPI45416.1 - 0.12 12.0 16.2 1.1 8.7 0.4 2.4 2 0 0 2 2 2 0 IncA protein DUF342 PF03961.8 KPI45416.1 - 0.25 9.6 8.2 0.23 9.8 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 KPI45416.1 - 2.4 7.7 15.9 1.6 8.3 4.5 2.4 2 0 0 2 2 2 0 Mnd1 family Pkinase PF00069.20 KPI45417.1 - 3.9e-70 235.9 0.0 4.6e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI45417.1 - 3.6e-31 108.1 0.0 6.3e-31 107.3 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI45417.1 - 0.00012 21.1 0.0 0.00023 20.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KPI45417.1 - 0.0075 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 KPI45417.1 - 0.0093 15.7 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KPI45417.1 - 0.091 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PIP5K PF01504.13 KPI45419.1 - 4.1e-57 193.1 0.0 1.1e-56 191.8 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KPI45419.1 - 1.4e-26 93.1 0.1 2.2e-26 92.5 0.1 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Proteasome PF00227.21 KPI45420.1 - 2.7e-49 167.0 0.1 3.4e-49 166.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Cellulase PF00150.13 KPI45421.1 - 5.2e-32 111.1 1.0 5.2e-32 111.1 0.7 1.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 KPI45421.1 - 0.0035 16.5 0.1 0.28 10.2 0.0 2.5 1 1 0 1 1 1 1 Beta-galactosidase Transp_cyt_pur PF02133.10 KPI45422.1 - 5e-101 338.4 39.0 6.3e-101 338.0 27.1 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ubie_methyltran PF01209.13 KPI45423.1 - 9.9e-82 273.5 0.0 1.3e-81 273.1 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KPI45423.1 - 1.9e-18 66.5 0.0 4.2e-18 65.3 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI45423.1 - 4.9e-14 52.5 0.0 1.9e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI45423.1 - 7.3e-12 45.5 0.0 1.4e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI45423.1 - 3.7e-11 43.3 0.0 6.2e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI45423.1 - 1.5e-09 37.7 0.1 2.9e-09 36.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI45423.1 - 2e-09 37.9 0.0 3.5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI45423.1 - 2.3e-06 27.6 0.0 4.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KPI45423.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Na_H_Exchanger PF00999.16 KPI45424.1 - 8e-31 106.9 16.9 1.3e-30 106.1 11.7 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3382 PF11862.3 KPI45424.1 - 0.09 12.6 6.0 0.027 14.3 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) DUF1229 PF06797.6 KPI45424.1 - 0.12 11.1 3.7 0.22 10.3 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) YrhC PF14143.1 KPI45424.1 - 7.9 6.5 8.9 1.4 8.8 0.1 3.9 4 0 0 4 4 4 0 YrhC-like protein adh_short PF00106.20 KPI45426.1 - 9.9e-24 84.1 0.1 1.1e-23 83.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI45426.1 - 2.4e-17 63.5 0.0 2.8e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI45426.1 - 9.4e-13 48.2 0.0 1.4e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KPI45426.1 - 0.0067 15.1 0.1 0.0092 14.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2235 PF09994.4 KPI45427.1 - 6.1e-36 124.2 0.0 1.2e-35 123.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Miro PF08477.8 KPI45427.1 - 3.1e-08 34.1 0.0 9.5e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KPI45427.1 - 6.1e-06 26.1 0.0 2e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 KPI45427.1 - 0.00012 21.2 0.1 0.00039 19.5 0.0 1.8 2 0 0 2 2 2 1 Septin DUF258 PF03193.11 KPI45427.1 - 0.00093 18.4 0.0 0.002 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KPI45427.1 - 0.006 15.7 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Gtr1_RagA PF04670.7 KPI45427.1 - 0.011 14.8 0.1 0.027 13.6 0.1 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region MobB PF03205.9 KPI45427.1 - 0.023 14.4 0.1 0.073 12.7 0.1 1.9 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KPI45427.1 - 0.025 14.8 0.1 0.095 12.9 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 KPI45427.1 - 0.035 13.6 0.0 0.078 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 KPI45427.1 - 0.041 14.0 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 KPI45427.1 - 0.043 14.6 0.0 0.13 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KPI45427.1 - 0.056 13.5 0.0 0.28 11.3 0.0 2.2 1 0 0 1 1 1 0 AAA domain Abhydrolase_5 PF12695.2 KPI45427.1 - 0.094 12.4 0.0 15 5.2 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family Dynamin_N PF00350.18 KPI45427.1 - 0.099 12.4 0.1 0.31 10.8 0.0 1.9 1 0 0 1 1 1 0 Dynamin family ATP_bind_1 PF03029.12 KPI45427.1 - 0.18 11.3 2.5 7.8 5.9 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PAN_1 PF00024.21 KPI45428.1 - 5.9e-06 25.9 5.0 0.17 11.6 0.5 3.4 3 0 0 3 3 3 3 PAN domain SKG6 PF08693.5 KPI45428.1 - 0.0098 15.1 0.2 0.02 14.2 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain adh_short PF00106.20 KPI45429.1 - 1.7e-14 54.0 0.2 3.6e-14 53.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KPI45429.1 - 2.6e-05 23.9 0.0 6.5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KPI45429.1 - 0.063 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 KPI45430.1 - 1.2e-21 77.7 0.0 4.4e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI45430.1 - 1.2e-17 63.3 0.5 5.2e-16 57.9 0.1 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KPI45430.1 - 2.6e-08 33.1 0.4 1.1e-06 27.7 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KPI45430.1 - 5.6e-08 32.6 2.6 5.7e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI45430.1 - 2e-05 24.5 0.0 7.3e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI45430.1 - 0.00054 19.7 0.5 0.028 14.1 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KPI45430.1 - 0.0049 15.8 4.2 0.059 12.2 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 KPI45430.1 - 0.06 12.4 0.1 1.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Thi4 family PP1_bind PF15276.1 KPI45430.1 - 0.22 11.5 0.2 0.52 10.3 0.1 1.5 1 0 0 1 1 1 0 Protein phosphatase 1 binding HI0933_like PF03486.9 KPI45430.1 - 3.8 5.8 4.7 1.2 7.5 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein Anillin PF08174.6 KPI45431.1 - 7.4e-24 84.3 0.0 2.4e-23 82.7 0.0 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 KPI45431.1 - 5.4e-08 32.9 0.0 1.6e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 KPI45431.1 - 0.0033 17.6 0.0 0.0068 16.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 KPI45432.1 - 7.9e-05 22.4 8.6 0.00015 21.4 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KPI45432.1 - 0.047 13.3 6.2 0.082 12.5 4.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI45432.1 - 0.062 13.0 5.9 0.1 12.3 4.1 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KPI45432.1 - 0.18 11.8 6.5 0.35 10.9 4.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) N-SET PF11764.3 KPI45433.1 - 3.2e-38 131.2 0.3 3.2e-38 131.2 0.2 2.9 2 1 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 KPI45433.1 - 3e-25 89.4 0.1 3e-25 89.4 0.1 3.1 2 2 0 2 2 2 1 SET domain SET_assoc PF11767.3 KPI45433.1 - 1e-10 40.7 0.0 2.1e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated RRM_1 PF00076.17 KPI45433.1 - 0.028 14.0 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI45433.1 - 0.03 14.3 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Herpes_UL25 PF01499.11 KPI45433.1 - 4 5.6 8.1 6.9 4.8 5.6 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family Cpn60_TCP1 PF00118.19 KPI45434.1 - 4.1e-133 444.5 8.3 4.9e-133 444.2 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PAD_M PF08527.5 KPI45434.1 - 0.06 12.7 0.1 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain Ppx-GppA PF02541.11 KPI45435.1 - 6.7e-36 123.9 0.0 1.4e-28 99.9 0.0 2.2 2 0 0 2 2 2 2 Ppx/GppA phosphatase family F-box-like PF12937.2 KPI45436.1 - 0.043 13.5 0.3 0.19 11.4 0.2 2.2 1 0 0 1 1 1 0 F-box-like F-box-like_2 PF13013.1 KPI45436.1 - 0.083 12.6 0.5 0.82 9.4 0.0 2.5 2 0 0 2 2 2 0 F-box-like domain adh_short PF00106.20 KPI45437.1 - 3e-30 105.3 0.0 4e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI45437.1 - 5.2e-27 95.1 0.0 6.9e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI45437.1 - 1.9e-12 47.2 0.0 2.6e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KPI45437.1 - 0.0011 18.7 0.1 0.0024 17.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KPI45437.1 - 0.0018 17.4 0.0 0.0027 16.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) TIR_2 PF13676.1 KPI45437.1 - 0.034 14.2 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 TIR domain THF_DHG_CYH_C PF02882.14 KPI45437.1 - 0.12 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Peptidase_M20 PF01546.23 KPI45438.1 - 8e-20 71.1 0.0 1.1e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KPI45438.1 - 2.1e-18 66.1 0.0 3.4e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KPI45438.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Y_phosphatase PF00102.22 KPI45439.1 - 7e-48 163.0 0.0 7.2e-21 74.5 0.0 3.3 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KPI45439.1 - 0.00086 19.5 0.0 0.0029 17.8 0.0 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KPI45439.1 - 0.0018 18.3 0.0 0.0053 16.8 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 KPI45439.1 - 0.044 13.3 0.1 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain PLA2_B PF01735.13 KPI45440.1 - 1.4e-195 650.1 1.0 1.9e-195 649.7 0.7 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Polyketide_cyc2 PF10604.4 KPI45440.1 - 0.0028 17.8 0.0 0.0078 16.3 0.0 1.7 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport UNC-50 PF05216.8 KPI45441.1 - 2e-05 23.9 2.9 2e-05 23.9 2.0 1.7 2 0 0 2 2 2 1 UNC-50 family MARVEL PF01284.18 KPI45441.1 - 5e-05 23.1 14.9 6.5e-05 22.7 10.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF456 PF04306.8 KPI45441.1 - 0.0029 17.6 3.2 0.024 14.6 1.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF456) DUF1469 PF07332.6 KPI45441.1 - 0.025 14.3 2.9 4.7 6.9 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) YbhQ PF11076.3 KPI45441.1 - 0.069 12.7 0.7 8.2 6.0 0.1 2.3 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ DUF3366 PF11846.3 KPI45441.1 - 0.097 12.5 3.5 0.31 10.8 1.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3366) DUF4282 PF14110.1 KPI45441.1 - 0.31 11.2 12.7 1.4 9.1 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4282) Reticulon PF02453.12 KPI45441.1 - 0.77 9.3 0.0 0.77 9.3 0.0 2.6 2 1 1 3 3 3 0 Reticulon SecY PF00344.15 KPI45441.1 - 0.91 8.3 6.0 13 4.5 4.1 2.1 1 1 0 1 1 1 0 SecY translocase zf-DHHC PF01529.15 KPI45441.1 - 1.3 8.3 5.9 18 4.6 4.1 2.1 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF1705 PF08019.7 KPI45441.1 - 1.5 8.3 7.1 0.65 9.4 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) VIT1 PF01988.14 KPI45441.1 - 7.1 6.0 11.6 22 4.4 5.7 2.1 2 0 0 2 2 2 0 VIT family SUR7 PF06687.7 KPI45441.1 - 9.5 5.7 10.7 17 4.9 5.7 2.0 1 1 1 2 2 2 0 SUR7/PalI family DUF3602 PF12223.3 KPI45442.1 - 3.3e-13 49.8 13.6 6.7e-12 45.6 2.6 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) AF1Q PF15017.1 KPI45443.1 - 0.014 15.2 0.8 0.03 14.1 0.6 1.5 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator CHCH PF06747.8 KPI45444.1 - 5.8e-05 22.9 5.2 8.9e-05 22.2 3.6 1.3 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 KPI45444.1 - 0.00044 20.3 1.1 0.00066 19.7 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) UPF0203 PF05254.7 KPI45444.1 - 0.14 12.0 4.4 0.49 10.2 3.1 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 KPI45444.1 - 0.15 11.8 2.4 0.61 9.9 0.2 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3584 PF12128.3 KPI45445.1 - 0.012 12.9 0.1 0.016 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Shisa PF13908.1 KPI45445.1 - 4.2 7.5 8.6 12 6.0 0.4 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator NmrA PF05368.8 KPI45446.1 - 7.4e-23 81.0 0.0 1e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI45446.1 - 7.7e-11 42.3 0.0 1.2e-10 41.7 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KPI45446.1 - 5.6e-07 29.8 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KPI45446.1 - 9.3e-05 21.4 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KPI45446.1 - 0.00019 20.2 0.0 0.00028 19.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KPI45446.1 - 0.012 15.5 0.0 0.04 13.8 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 KPI45446.1 - 0.027 13.8 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KPI45446.1 - 0.027 13.4 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF2062 PF09835.4 KPI45447.1 - 0.016 14.8 0.4 0.032 13.8 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) TFIIA PF03153.8 KPI45448.1 - 5.5 6.7 19.4 0.5 10.2 0.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TLD PF07534.11 KPI45449.1 - 3.8e-12 46.3 0.0 8.6e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 TLD NmrA PF05368.8 KPI45451.1 - 3.3e-14 52.6 0.1 4.6e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KPI45451.1 - 3.9e-14 53.0 0.3 6.9e-14 52.2 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KPI45451.1 - 1.5e-05 25.2 0.1 2.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KPI45451.1 - 2.7e-05 23.0 0.1 7.8e-05 21.5 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KPI45451.1 - 3.3e-05 23.8 0.2 5.7e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 KPI45451.1 - 0.00035 20.0 0.1 0.0015 18.0 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 KPI45451.1 - 0.03 14.2 0.1 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 KPI45451.1 - 0.06 13.7 0.1 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 KPI45451.1 - 0.1 13.1 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NIPSNAP PF07978.8 KPI45452.1 - 2.8e-14 52.9 0.0 7.4e-14 51.5 0.0 1.6 2 0 0 2 2 2 1 NIPSNAP Herpes_LMP1 PF05297.6 KPI45453.1 - 2.9 6.7 8.9 0.28 10.0 2.1 2.3 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) GMC_oxred_N PF00732.14 KPI45454.1 - 1.5e-65 221.3 0.0 1.9e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KPI45454.1 - 5.2e-31 107.8 0.0 1.1e-30 106.7 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KPI45454.1 - 2.2e-12 46.5 0.0 1.4e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI45454.1 - 7.5e-10 38.2 2.0 0.00068 18.6 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KPI45454.1 - 5.7e-06 25.4 0.2 9.6e-06 24.7 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 KPI45454.1 - 1.5e-05 24.0 0.0 0.077 11.8 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KPI45454.1 - 1.6e-05 25.0 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI45454.1 - 4.2e-05 23.4 0.8 0.00014 21.7 0.6 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI45454.1 - 6.1e-05 22.9 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KPI45454.1 - 0.0012 19.2 0.0 0.022 15.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI45454.1 - 0.0089 15.8 0.4 1.2 8.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KPI45454.1 - 0.013 14.6 3.7 2.3 7.1 1.3 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KPI45454.1 - 0.045 12.7 0.0 0.089 11.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KPI45454.1 - 0.05 12.0 0.2 0.085 11.3 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KPI45454.1 - 0.065 12.3 0.3 0.12 11.4 0.2 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 KPI45454.1 - 0.12 12.3 0.2 1.3 9.0 0.0 2.5 2 1 1 3 3 3 0 TrkA-N domain Trp_halogenase PF04820.9 KPI45454.1 - 0.13 10.8 0.3 0.23 10.0 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.1 KPI45454.1 - 0.18 10.7 0.1 0.58 9.0 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Borrelia_lipo_2 PF06238.6 KPI45455.1 - 0.091 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi BBR25 lipoprotein Voltage_CLC PF00654.15 KPI45456.1 - 2.4e-89 299.8 28.2 2.4e-89 299.8 19.6 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KPI45456.1 - 0.0021 17.8 0.0 0.031 14.0 0.0 2.4 2 0 0 2 2 2 1 CBS domain Fungal_trans PF04082.13 KPI45457.1 - 7.4e-11 41.4 2.2 2.5e-10 39.6 0.0 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain CS PF04969.11 KPI45458.1 - 1.6e-16 60.5 0.2 3.1e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 CS domain Na_H_Exchanger PF00999.16 KPI45459.1 - 4.8e-27 94.4 38.9 7e-23 80.7 18.1 2.8 3 0 0 3 3 3 2 Sodium/hydrogen exchanger family HET PF06985.6 KPI45460.1 - 5e-33 114.1 0.2 1.2e-32 112.9 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.8 KPI45460.1 - 0.008 15.1 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Fungal_trans PF04082.13 KPI45461.1 - 0.053 12.3 2.8 0.061 12.1 0.2 2.1 1 1 0 2 2 2 0 Fungal specific transcription factor domain FAD_binding_4 PF01565.18 KPI45462.1 - 2.2e-24 85.4 0.0 5.8e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain DUF4577 PF15145.1 KPI45462.1 - 0.25 11.2 0.1 19 5.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) AAA PF00004.24 KPI45463.1 - 3.1e-20 72.7 0.0 1e-18 67.8 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KPI45463.1 - 0.00042 19.9 0.0 0.0015 18.2 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KPI45463.1 - 0.0013 18.5 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF851 PF05867.6 KPI45463.1 - 0.0013 18.0 0.0 0.0025 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF851) AAA_17 PF13207.1 KPI45463.1 - 0.0015 19.3 0.1 0.0086 16.8 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KPI45463.1 - 0.0018 18.2 1.6 0.026 14.5 0.0 3.2 3 1 1 4 4 4 1 AAA ATPase domain AAA_18 PF13238.1 KPI45463.1 - 0.0027 17.9 0.0 0.04 14.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain KaiC PF06745.8 KPI45463.1 - 0.0037 16.4 0.3 0.0067 15.5 0.2 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 KPI45463.1 - 0.007 15.7 0.0 0.018 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KPI45463.1 - 0.0071 15.4 0.1 0.016 14.3 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 KPI45463.1 - 0.0089 16.1 0.3 0.14 12.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain Zot PF05707.7 KPI45463.1 - 0.013 14.9 0.2 0.27 10.6 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_33 PF13671.1 KPI45463.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KPI45463.1 - 0.024 14.5 0.7 0.16 11.9 0.1 2.5 2 1 1 3 3 3 0 AAA domain AAA_30 PF13604.1 KPI45463.1 - 0.025 14.1 0.1 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KPI45463.1 - 0.025 13.9 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 KPI45463.1 - 0.028 13.6 0.7 0.083 12.0 0.3 1.8 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 KPI45463.1 - 0.043 12.8 0.0 0.095 11.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Vps36_ESCRT-II PF11605.3 KPI45463.1 - 0.095 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 AAA_11 PF13086.1 KPI45463.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KPI45463.1 - 0.2 10.3 0.1 0.3 9.7 0.1 1.2 1 0 0 1 1 1 0 TIP49 C-terminus adh_short PF00106.20 KPI45464.1 - 1.5e-05 24.9 0.4 0.00028 20.8 0.1 3.4 3 1 1 4 4 4 2 short chain dehydrogenase NAD_binding_10 PF13460.1 KPI45464.1 - 0.018 15.0 0.1 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding Exo_endo_phos PF03372.18 KPI45465.1 - 1.2e-07 31.9 0.4 1.9e-07 31.3 0.3 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF346 PF03984.8 KPI45465.1 - 0.019 14.4 0.5 0.054 12.9 0.3 1.8 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) 2Fe-2S_thioredx PF01257.14 KPI45466.1 - 7.4e-60 200.7 0.1 9.3e-60 200.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Taxilin PF09728.4 KPI45468.1 - 4.6e-84 282.1 59.7 4.6e-84 282.1 41.4 2.2 2 1 1 3 3 3 1 Myosin-like coiled-coil protein TMF_DNA_bd PF12329.3 KPI45468.1 - 0.041 13.6 0.9 0.041 13.6 0.6 7.0 4 2 3 7 7 7 0 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KPI45468.1 - 1.4 8.0 6.2 6.6 5.8 0.2 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Amidohydro_1 PF01979.15 KPI45469.1 - 1.4e-17 64.4 0.3 2.3e-17 63.6 0.2 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KPI45469.1 - 9.2e-13 47.8 1.2 2.3e-12 46.5 0.1 2.4 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 KPI45469.1 - 4.4e-08 33.4 2.1 1.9e-05 24.8 1.5 2.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KPI45469.1 - 9.3e-07 28.3 0.0 0.00037 19.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family GTP_EFTU PF00009.22 KPI45471.1 - 7.5e-55 185.2 0.0 1.5e-54 184.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KPI45471.1 - 3.7e-32 109.9 0.0 7.9e-32 108.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KPI45471.1 - 2.7e-21 75.2 0.1 1.3e-20 73.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_IV PF03764.13 KPI45471.1 - 1.4e-16 60.1 0.7 2.9e-09 36.5 0.0 2.5 1 1 1 2 2 2 2 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 KPI45471.1 - 7.7e-13 48.3 0.0 2.8e-12 46.5 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 adh_short PF00106.20 KPI45472.1 - 7e-34 117.1 0.1 8.7e-34 116.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI45472.1 - 4.4e-18 65.9 0.0 5.5e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI45472.1 - 9.9e-14 51.3 0.1 1.3e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KPI45472.1 - 6.1e-10 38.7 0.0 7.7e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KPI45472.1 - 1.7e-05 24.9 0.1 5.8e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI45472.1 - 5.4e-05 22.7 0.1 0.00012 21.5 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KPI45472.1 - 0.0075 16.0 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Abhydrolase_6 PF12697.2 KPI45473.1 - 5.4e-10 39.5 0.0 1.9e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI45473.1 - 1.1e-08 34.9 0.0 3.8e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI45473.1 - 8.6e-05 22.1 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 KPI45473.1 - 0.0025 17.2 0.0 0.0073 15.7 0.0 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 KPI45473.1 - 0.015 15.1 0.1 0.066 13.0 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase Peptidase_S28 PF05577.7 KPI45473.1 - 0.036 12.6 0.0 0.061 11.8 0.0 1.4 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Perm-CXXC PF15629.1 KPI45474.1 - 0.4 10.7 3.6 0.89 9.6 2.5 1.5 1 0 0 1 1 1 0 Permuted single zf-CXXC unit ACC_central PF08326.7 KPI45475.1 - 1.6e-226 753.7 0.0 2e-145 485.7 0.0 2.1 2 0 0 2 2 2 2 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KPI45475.1 - 6.7e-168 559.0 0.0 1.1e-167 558.3 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KPI45475.1 - 4.3e-53 179.7 0.0 8e-53 178.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KPI45475.1 - 2.5e-24 85.5 0.1 4.6e-24 84.6 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KPI45475.1 - 7e-24 83.8 0.0 6e-21 74.4 0.0 3.6 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KPI45475.1 - 6.1e-15 54.6 0.1 1.4e-14 53.4 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KPI45475.1 - 2.6e-12 46.8 0.0 1.2e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KPI45475.1 - 6.9e-09 34.8 0.0 1.5e-06 27.2 0.0 3.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KPI45475.1 - 2.2e-05 23.9 0.0 6.4e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KPI45475.1 - 0.00051 19.9 0.0 0.0019 18.0 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 KPI45475.1 - 0.0021 17.4 0.0 0.0048 16.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KPI45475.1 - 0.046 13.1 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Methyltransf_25 PF13649.1 KPI45476.1 - 4.1e-05 23.8 0.0 7.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI45476.1 - 0.014 15.8 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 4HBT PF03061.17 KPI45477.1 - 8.3e-08 32.2 0.3 1.6e-07 31.3 0.2 1.6 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.1 KPI45477.1 - 0.05 13.3 3.1 0.15 11.7 2.2 1.8 1 1 0 1 1 1 0 Thioesterase-like superfamily BNR PF02012.15 KPI45478.1 - 0.00089 18.7 3.4 1.1 9.3 0.1 3.8 3 0 0 3 3 3 2 BNR/Asp-box repeat MFS_1 PF07690.11 KPI45479.1 - 8.8e-28 97.0 28.9 8.8e-28 97.0 20.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI45479.1 - 3.8e-10 38.9 5.0 3.8e-10 38.9 3.5 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter Zn_clus PF00172.13 KPI45480.1 - 0.0012 18.7 8.2 0.0021 17.9 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KPI45480.1 - 0.0049 15.5 0.0 0.0075 14.9 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain SHR3_chaperone PF08229.6 KPI45481.1 - 1.3e-50 171.0 7.0 3.4e-34 117.5 1.8 2.0 1 1 1 2 2 2 2 ER membrane protein SH3 Tad PF13400.1 KPI45481.1 - 0.31 11.0 2.6 0.69 9.9 0.0 2.4 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like NAD_binding_10 PF13460.1 KPI45482.1 - 2.2e-14 53.8 0.0 3.1e-13 50.1 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KPI45482.1 - 1.1e-06 28.2 0.0 3.7e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KPI45482.1 - 1.6e-05 23.8 0.0 0.00011 20.9 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KPI45482.1 - 0.00039 20.3 0.0 0.0082 16.0 0.0 2.6 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KPI45482.1 - 0.0011 17.9 0.0 0.44 9.4 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 KPI45482.1 - 0.052 12.4 0.0 1.6 7.5 0.0 2.7 3 0 0 3 3 3 0 RmlD substrate binding domain zf-RING_2 PF13639.1 KPI45484.1 - 3.1e-11 42.9 6.3 5.5e-11 42.1 4.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KPI45484.1 - 2.8e-08 33.2 1.0 5.4e-08 32.3 0.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI45484.1 - 3.4e-07 29.8 3.1 5.4e-07 29.2 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KPI45484.1 - 8.7e-07 28.8 4.7 1.7e-06 27.9 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI45484.1 - 1.7e-06 27.5 3.9 3.1e-06 26.7 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KPI45484.1 - 0.00095 19.2 7.5 0.0026 17.8 5.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KPI45484.1 - 0.014 15.0 1.9 0.026 14.2 1.3 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KPI45484.1 - 0.052 13.4 3.0 0.12 12.2 2.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ebola_NP PF05505.7 KPI45484.1 - 0.15 10.1 0.0 0.19 9.7 0.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein FANCL_C PF11793.3 KPI45484.1 - 0.18 11.7 5.7 1.3 9.0 3.5 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-Apc11 PF12861.2 KPI45484.1 - 0.29 10.9 4.3 0.73 9.7 3.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KPI45484.1 - 0.31 11.1 6.6 0.81 9.7 4.6 1.8 1 1 0 1 1 1 0 RING-variant domain DUF588 PF04535.7 KPI45484.1 - 0.48 9.9 3.5 2 7.9 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF588) SAGA-Tad1 PF12767.2 KPI45485.1 - 5.6e-46 157.2 0.0 7.7e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit NADH_u_ox_C PF12853.2 KPI45485.1 - 0.063 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit TENA_THI-4 PF03070.11 KPI45487.1 - 9.6e-12 45.0 0.0 5e-10 39.4 0.0 2.8 1 1 0 1 1 1 1 TENA/THI-4/PQQC family LtrA PF06772.6 KPI45488.1 - 7.7e-20 71.0 21.5 1.3e-19 70.3 14.1 1.8 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) TrbC PF04956.8 KPI45488.1 - 0.083 12.9 0.3 0.083 12.9 0.2 3.2 4 1 0 4 4 4 0 TrbC/VIRB2 family ZZ PF00569.12 KPI45489.1 - 5.4e-06 25.8 9.1 5.4e-06 25.8 6.3 2.8 3 0 0 3 3 3 1 Zinc finger, ZZ type zf-4CXXC_R1 PF10497.4 KPI45489.1 - 0.00018 21.5 9.2 0.00018 21.5 6.4 2.4 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 JmjC PF02373.17 KPI45489.1 - 0.0044 17.2 0.0 0.0091 16.2 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase 2OG-FeII_Oxy_5 PF13759.1 KPI45489.1 - 0.066 13.5 0.1 6.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase FAA_hydrolase PF01557.13 KPI45490.1 - 1.2e-48 165.4 0.0 5.2e-47 160.1 0.0 2.1 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SNF2_N PF00176.18 KPI45491.1 - 1.1e-73 247.6 0.0 1.9e-73 246.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KPI45491.1 - 2.1e-10 40.2 0.0 4.5e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3533 PF12051.3 KPI45491.1 - 0.73 8.5 1.1 1.2 7.8 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Pkinase PF00069.20 KPI45493.1 - 3.5e-57 193.5 0.0 4.3e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI45493.1 - 4.4e-31 107.8 0.0 6.3e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FAD_binding_3 PF01494.14 KPI45494.1 - 9.6e-14 51.1 0.0 1.8e-13 50.2 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI45494.1 - 9.3e-07 28.0 0.0 7.5e-05 21.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KPI45494.1 - 3.3e-05 24.1 0.0 0.0002 21.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KPI45494.1 - 7.8e-05 22.6 0.0 0.00042 20.2 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI45494.1 - 0.00022 21.1 0.1 0.00093 19.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KPI45494.1 - 0.00047 18.7 0.0 0.0011 17.5 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein SE PF08491.5 KPI45494.1 - 0.0071 15.1 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_2 PF00890.19 KPI45494.1 - 0.013 14.3 0.1 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 KPI45494.1 - 0.035 12.7 0.4 4 5.9 0.0 2.9 3 0 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.17 KPI45494.1 - 0.035 12.9 0.1 0.064 12.0 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 KPI45494.1 - 0.058 12.4 4.0 0.1 11.6 1.4 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KPI45494.1 - 0.082 12.5 0.1 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 KPI45494.1 - 0.22 11.5 0.8 0.87 9.6 0.6 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rif1_N PF12231.3 KPI45495.1 - 5.2e-16 58.5 0.3 6.3e-16 58.2 0.2 1.1 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Abhydrolase_3 PF07859.8 KPI45496.1 - 1.1e-17 64.3 0.0 1.5e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI45496.1 - 6.2e-12 45.2 0.0 2e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KPI45496.1 - 1.1e-06 28.4 0.0 2.5e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KPI45496.1 - 1.6e-06 27.1 0.0 2.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.23 KPI45496.1 - 5.1e-05 22.1 0.0 9.7e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Esterase PF00756.15 KPI45496.1 - 0.00055 19.4 0.0 0.0015 17.9 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.6 KPI45496.1 - 0.0014 17.4 0.0 0.002 17.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase AXE1 PF05448.7 KPI45496.1 - 0.0023 16.5 0.0 0.25 9.7 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 KPI45496.1 - 0.0061 16.4 0.0 0.0099 15.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KPI45496.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Pam17 PF08566.5 KPI45498.1 - 5.9e-55 185.6 0.1 7.5e-55 185.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Colicin_V PF02674.11 KPI45498.1 - 0.012 15.5 0.1 0.017 14.9 0.1 1.2 1 0 0 1 1 1 0 Colicin V production protein AtpR PF12966.2 KPI45498.1 - 0.11 12.6 1.4 6.1 7.0 0.1 2.4 2 0 0 2 2 2 0 N-ATPase, AtpR subunit CUE PF02845.11 KPI45499.1 - 0.0048 16.3 0.1 0.014 14.8 0.0 1.8 2 0 0 2 2 2 1 CUE domain MutS_V PF00488.16 KPI45500.1 - 1.8e-85 286.0 0.0 3e-85 285.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KPI45500.1 - 1.5e-37 129.3 0.2 2.7e-37 128.5 0.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KPI45500.1 - 2.1e-29 101.8 0.0 4.3e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KPI45500.1 - 7.6e-08 32.5 0.0 4e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 KPI45500.1 - 0.00046 20.3 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV MFS_1 PF07690.11 KPI45502.1 - 1.5e-32 112.7 17.0 2e-32 112.3 11.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily RNase_T PF00929.19 KPI45503.1 - 5.4e-09 36.5 0.0 8.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease SPT6_acidic PF14632.1 KPI45503.1 - 0.25 11.5 1.6 0.52 10.5 1.1 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 PHO4 PF01384.15 KPI45504.1 - 1.5e-99 332.7 17.5 1.8e-99 332.5 12.1 1.1 1 0 0 1 1 1 1 Phosphate transporter family CAML PF14963.1 KPI45505.1 - 0.067 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand TRIQK PF15168.1 KPI45505.1 - 0.12 12.3 5.9 0.26 11.2 0.1 3.0 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family AMA-1 PF02430.10 KPI45505.1 - 0.18 10.6 1.3 0.21 10.4 0.2 1.5 2 0 0 2 2 2 0 Apical membrane antigen 1 DUF373 PF04123.8 KPI45505.1 - 0.19 10.7 1.2 0.32 9.9 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) MARVEL PF01284.18 KPI45505.1 - 0.2 11.4 12.2 0.11 12.3 6.1 2.2 1 1 1 2 2 2 0 Membrane-associating domain DUF4381 PF14316.1 KPI45505.1 - 0.25 11.4 2.7 6.7 6.8 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Vpu PF00558.14 KPI45505.1 - 5.6 6.5 7.0 1.4 8.5 0.8 2.4 2 0 0 2 2 2 0 Vpu protein AMP-binding PF00501.23 KPI45506.1 - 5.3e-88 295.2 0.0 6.2e-88 294.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI45506.1 - 3.9e-10 40.5 0.1 9.7e-10 39.2 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF605 PF04652.11 KPI45507.1 - 0.043 13.2 15.4 0.055 12.8 10.7 1.0 1 0 0 1 1 1 0 Vta1 like Orbi_NS3 PF01616.11 KPI45508.1 - 0.087 11.7 0.3 0.17 10.8 0.2 1.4 1 0 0 1 1 1 0 Orbivirus NS3 WWbp PF10349.4 KPI45508.1 - 2.4 9.0 9.1 2.9 8.8 4.4 2.0 2 0 0 2 2 2 0 WW-domain ligand protein UCH PF00443.24 KPI45510.1 - 1.7e-23 83.1 0.0 8.1e-23 80.8 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KPI45510.1 - 4.9e-12 45.7 0.5 8.5e-12 45.0 0.3 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KPI45510.1 - 0.00071 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase G-patch_2 PF12656.2 KPI45511.1 - 4.6e-20 71.2 0.3 3.5e-19 68.4 0.2 2.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site DUF3328 PF11807.3 KPI45512.1 - 2e-35 122.4 0.2 2.5e-35 122.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Adeno_E3_CR2 PF02439.10 KPI45514.1 - 0.05 13.1 0.9 0.11 12.1 0.6 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Binary_toxB PF03495.9 KPI45514.1 - 2.6 6.5 5.9 3.6 6.1 4.1 1.2 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA BolA PF01722.13 KPI45515.1 - 2.1e-28 98.0 0.9 2.5e-28 97.8 0.6 1.1 1 0 0 1 1 1 1 BolA-like protein Glyco_transf_22 PF03901.12 KPI45516.1 - 5.4e-80 269.4 8.9 6.8e-80 269.0 6.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Ribosomal_L5_C PF00673.16 KPI45517.1 - 8.9e-23 79.8 0.0 1.2e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KPI45517.1 - 3.7e-21 74.6 0.0 1e-20 73.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 YL1 PF05764.8 KPI45518.1 - 4.5e-44 150.8 34.8 8.3e-44 149.9 24.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.6 KPI45518.1 - 2.6e-10 39.6 0.0 4.8e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain WW PF00397.21 KPI45519.1 - 1.4e-08 34.4 0.6 1.4e-08 34.4 0.4 2.1 2 0 0 2 2 2 1 WW domain PhoD PF09423.5 KPI45519.1 - 0.0022 16.6 0.1 0.0035 15.9 0.1 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase Methyltransf_23 PF13489.1 KPI45520.1 - 2.7e-14 53.2 0.0 4.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI45520.1 - 1.4e-09 38.3 0.0 3.1e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI45520.1 - 2.7e-07 30.9 0.0 7.4e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI45520.1 - 8.8e-06 26.2 0.0 1.3e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI45520.1 - 0.0001 21.9 0.0 0.00035 20.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI45520.1 - 0.012 15.6 0.1 0.032 14.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KPI45520.1 - 0.16 11.0 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Glyco_hydro_16 PF00722.16 KPI45521.1 - 2.4e-09 36.7 0.0 2.4e-09 36.7 0.0 4.0 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 MFS_1 PF07690.11 KPI45522.1 - 7.9e-40 136.6 50.7 7.9e-40 136.6 35.2 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily PUCC PF03209.10 KPI45522.1 - 0.00034 19.4 5.7 0.00034 19.4 3.9 2.8 3 1 0 3 3 3 1 PUCC protein DUF997 PF06196.7 KPI45522.1 - 0.024 14.1 0.6 0.024 14.1 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF997) DLH PF01738.13 KPI45523.1 - 9.4e-30 103.5 0.0 1.3e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KPI45523.1 - 7.1e-06 25.8 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI45523.1 - 0.049 13.1 0.1 0.15 11.6 0.1 1.6 1 1 0 2 2 2 0 alpha/beta hydrolase fold Y_phosphatase3 PF13350.1 KPI45524.1 - 3.7e-29 102.1 0.0 6.5e-28 98.0 0.0 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 KPI45524.1 - 1.3e-08 34.4 0.0 3.2e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KPI45524.1 - 4.2e-06 26.7 0.0 7.7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 KPI45524.1 - 0.00085 18.7 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KPI45524.1 - 0.014 14.9 0.0 0.067 12.7 0.0 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 KPI45524.1 - 0.017 13.9 0.1 0.024 13.4 0.1 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain HATPase_c_3 PF13589.1 KPI45525.1 - 0.0059 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3883 PF13020.1 KPI45525.1 - 0.024 14.3 0.0 0.088 12.5 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) PK_C PF02887.11 KPI45525.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain Iso_dh PF00180.15 KPI45526.1 - 1.3e-95 320.3 0.0 1.7e-94 316.6 0.0 1.9 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Cutinase PF01083.17 KPI45527.1 - 6.1e-56 188.9 0.1 7.2e-56 188.7 0.1 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KPI45527.1 - 0.0005 19.5 0.1 0.00073 19.0 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Lipase_3 PF01764.20 KPI45527.1 - 0.0078 15.8 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 KPI45527.1 - 0.0079 15.5 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 KPI45527.1 - 0.025 14.3 0.1 0.032 14.0 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KPI45527.1 - 0.044 13.2 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KPI45527.1 - 0.074 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Response_reg PF00072.19 KPI45528.1 - 1.8e-22 79.4 0.5 3.3e-14 52.8 0.0 2.8 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.21 KPI45528.1 - 8.3e-20 70.5 0.0 2e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 KPI45528.1 - 1.2e-06 28.8 0.0 3e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 PAS domain HisKA PF00512.20 KPI45528.1 - 1.4e-06 28.2 0.1 1.4e-06 28.2 0.1 2.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 KPI45528.1 - 7e-05 23.3 0.0 0.045 14.2 0.0 2.7 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 KPI45528.1 - 0.00057 19.9 0.0 0.003 17.6 0.0 2.3 1 0 0 1 1 1 1 GAF domain PAS PF00989.19 KPI45528.1 - 0.0044 16.7 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 KPI45528.1 - 0.01 15.8 0.0 0.16 12.0 0.0 2.9 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.1 KPI45528.1 - 0.024 14.5 0.0 0.071 13.0 0.0 1.8 1 0 0 1 1 1 0 PAS domain DUF3812 PF12757.2 KPI45529.1 - 2.3e-37 127.7 15.0 2.3e-37 127.7 10.4 4.9 4 1 0 4 4 4 1 Protein of unknown function (DUF3812) MutS_V PF00488.16 KPI45530.1 - 1.9e-67 227.0 0.2 1.3e-66 224.3 0.1 2.2 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KPI45530.1 - 6.8e-48 163.1 0.0 1.3e-47 162.2 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KPI45530.1 - 4.3e-32 110.4 0.1 9.8e-32 109.3 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 KPI45530.1 - 3.5e-15 55.9 0.6 1.5e-14 53.9 0.4 2.2 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 KPI45530.1 - 5.1e-10 39.5 0.0 1.2e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 KPI45530.1 - 0.01 15.3 0.2 0.01 15.3 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KPI45530.1 - 0.018 15.3 1.7 0.086 13.1 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KPI45530.1 - 0.039 13.9 0.1 2.1 8.2 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Hemagglutinin PF00509.13 KPI45530.1 - 0.062 11.4 0.0 0.1 10.7 0.0 1.2 1 0 0 1 1 1 0 Haemagglutinin AAA_21 PF13304.1 KPI45530.1 - 0.087 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain MCM_N PF14551.1 KPI45531.1 - 0.11 12.9 0.1 0.21 12.0 0.0 1.4 1 1 0 1 1 1 0 MCM N-terminal domain DUF3533 PF12051.3 KPI45532.1 - 6.7e-115 383.8 17.6 7.8e-115 383.6 12.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF3671 PF12420.3 KPI45533.1 - 0.11 12.4 0.8 0.14 12.1 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF4257 PF14074.1 KPI45533.1 - 0.12 12.0 0.5 0.21 11.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) DUF4131 PF13567.1 KPI45533.1 - 2.2 7.6 5.9 3.9 6.8 4.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Herpes_gE PF02480.11 KPI45535.1 - 0.00027 19.3 0.0 0.00029 19.2 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Shisa PF13908.1 KPI45535.1 - 0.064 13.4 0.0 0.11 12.6 0.0 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2254 PF10011.4 KPI45535.1 - 0.15 10.4 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF1049 PF06305.6 KPI45535.1 - 0.21 11.1 1.1 0.32 10.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Glyco_transf_20 PF00982.16 KPI45536.1 - 6.1e-143 476.7 0.0 3.1e-141 471.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 KPI45536.1 - 0.0012 18.3 0.0 0.27 10.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 DUF4440 PF14534.1 KPI45537.1 - 0.028 14.6 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 KPI45537.1 - 0.044 14.1 0.0 0.063 13.6 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain p450 PF00067.17 KPI45539.1 - 1.5e-52 178.6 0.0 2.2e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KPI45540.1 - 2e-29 102.4 17.4 2e-29 102.4 12.0 2.8 3 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KPI45540.1 - 1.3e-09 36.8 11.8 4.2e-09 35.1 8.1 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PfkB PF00294.19 KPI45541.1 - 4.7e-13 48.9 0.0 1.2e-12 47.5 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Ribosomal_L36e PF01158.13 KPI45542.1 - 3.1e-40 136.1 6.6 3.5e-40 135.9 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Bac_rhodopsin PF01036.13 KPI45543.1 - 8e-46 156.1 16.9 9.5e-46 155.8 11.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Wzy_C PF04932.10 KPI45543.1 - 0.0062 16.3 0.2 0.0062 16.3 0.1 2.3 1 1 1 2 2 2 1 O-Antigen ligase DUF4131 PF13567.1 KPI45543.1 - 0.16 11.3 4.6 0.7 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) tRNA-synt_1g PF09334.6 KPI45544.1 - 2e-75 253.8 0.4 3.2e-75 253.2 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KPI45544.1 - 1.7e-12 46.2 0.5 3.8e-08 31.8 0.2 3.0 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KPI45544.1 - 8.5e-05 21.8 0.0 0.00012 21.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Peptidase_C28 PF05408.6 KPI45544.1 - 0.013 14.9 0.1 0.027 13.9 0.0 1.6 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase Peripla_BP_3 PF13377.1 KPI45544.1 - 0.074 13.0 0.0 2.3 8.1 0.0 2.2 1 1 1 2 2 2 0 Periplasmic binding protein-like domain Aminotran_5 PF00266.14 KPI45545.1 - 1.1e-23 83.6 0.0 1.6e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MOSC PF03473.12 KPI45545.1 - 4.6e-20 71.4 0.0 9.6e-20 70.4 0.0 1.6 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 KPI45545.1 - 1.5e-18 66.6 0.0 7e-18 64.4 0.0 2.2 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain Fungal_trans PF04082.13 KPI45546.1 - 1.5e-21 76.4 1.6 4.5e-21 74.8 1.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain CHCH PF06747.8 KPI45546.1 - 0.0019 18.0 0.7 0.0057 16.5 0.3 2.0 2 0 0 2 2 2 1 CHCH domain Luciferase_N PF05295.6 KPI45546.1 - 0.0073 16.0 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 Luciferase/LBP N-terminal domain NatB_MDM20 PF09797.4 KPI45548.1 - 8.7e-34 116.8 0.0 3e-33 115.0 0.0 1.8 1 1 1 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.1 KPI45548.1 - 0.017 15.7 8.5 65 4.5 0.4 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Not1 PF04054.10 KPI45548.1 - 0.076 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 DUF1593 PF07632.6 KPI45549.1 - 2.7e-66 223.5 0.1 3.8e-66 223.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 KPI45549.1 - 0.0055 15.0 0.0 0.0072 14.6 0.0 1.2 1 0 0 1 1 1 1 REJ domain Sirohm_synth_C PF14823.1 KPI45549.1 - 0.14 11.4 1.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal Ecm29 PF13001.2 KPI45550.1 - 7.2e-78 262.2 5.0 2.4e-40 138.4 1.1 2.7 1 1 1 2 2 2 2 Proteasome stabiliser Fungal_trans_2 PF11951.3 KPI45550.1 - 2.7e-13 49.3 4.0 2e-12 46.4 2.8 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain HEAT PF02985.17 KPI45550.1 - 0.00081 19.2 14.7 15 6.0 0.0 9.8 13 0 0 13 13 13 1 HEAT repeat Vac14_Fab1_bd PF12755.2 KPI45550.1 - 0.016 15.5 0.1 9.9 6.6 0.0 4.3 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region SIR2 PF02146.12 KPI45552.1 - 9.3e-38 129.7 0.0 1.4e-24 86.7 0.0 2.1 2 0 0 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.17 KPI45552.1 - 0.05 13.3 0.3 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain EKR PF10371.4 KPI45552.1 - 0.13 11.8 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DAHP_synth_2 PF01474.11 KPI45553.1 - 8.8e-184 610.9 0.0 1e-183 610.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family MFS_1 PF07690.11 KPI45554.1 - 4.4e-07 28.9 32.9 1.2e-06 27.4 20.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 KPI45554.1 - 0.0015 18.0 10.2 0.0039 16.6 2.9 3.2 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 M16C_assoc PF08367.6 KPI45555.1 - 9.4e-52 175.3 0.0 1.8e-51 174.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 KPI45555.1 - 2.5e-26 92.5 0.0 2.5e-15 56.6 0.0 4.0 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KPI45555.1 - 7.6e-06 25.7 0.0 5.4e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Tyrosinase PF00264.15 KPI45556.1 - 1.6e-46 159.2 0.1 2.5e-46 158.6 0.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase COesterase PF00135.23 KPI45557.1 - 1.2e-90 304.7 0.0 1.6e-90 304.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KPI45557.1 - 9.8e-06 25.2 0.0 0.00018 21.1 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KPI45557.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family 4HBT PF03061.17 KPI45557.1 - 0.024 14.7 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily Cullin PF00888.17 KPI45558.1 - 2.4e-42 145.2 0.0 4.2e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 KPI45558.1 - 4.5e-22 78.0 0.0 3.5e-21 75.1 0.0 2.5 3 0 0 3 3 3 1 Anaphase promoting complex (APC) subunit 2 Ribosomal_60s PF00428.14 KPI45558.1 - 0.0045 17.3 5.9 0.0045 17.3 4.1 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein Bcl-2_3 PF15286.1 KPI45558.1 - 0.14 12.6 0.8 1.9 8.9 0.0 2.7 2 1 0 2 2 2 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like VTC PF09359.5 KPI45560.1 - 4.2e-99 331.1 0.0 7e-99 330.3 0.0 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KPI45560.1 - 3.5e-18 66.3 13.7 3.5e-18 66.3 9.5 4.1 3 1 0 3 3 3 1 SPX domain Fungal_trans PF04082.13 KPI45560.1 - 7.7e-16 57.7 0.0 1.4e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF202 PF02656.10 KPI45560.1 - 3.6e-10 39.9 5.5 7.9e-10 38.8 3.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Zn_clus PF00172.13 KPI45560.1 - 0.01 15.7 1.2 0.019 14.8 0.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Evr1_Alr PF04777.8 KPI45561.1 - 2e-25 88.5 1.1 4.1e-25 87.5 0.4 1.6 1 1 1 2 2 2 1 Erv1 / Alr family WBS_methylT PF12589.3 KPI45563.1 - 1e-15 57.9 3.4 1e-15 57.9 2.4 1.6 2 0 0 2 2 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KPI45563.1 - 3.2e-15 56.3 0.0 5.6e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI45563.1 - 1.5e-09 37.6 0.0 2.3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI45563.1 - 1.6e-08 34.5 0.0 2.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI45563.1 - 1.8e-08 34.2 0.0 2.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI45563.1 - 2.1e-08 34.4 0.0 4.5e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI45563.1 - 3.9e-08 33.6 0.0 9.5e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI45563.1 - 2e-07 31.5 0.0 4.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KPI45563.1 - 0.0012 18.4 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KPI45563.1 - 0.004 16.2 0.0 0.013 14.6 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 KPI45563.1 - 0.0043 16.1 0.1 0.014 14.5 0.0 1.9 3 1 0 3 3 3 1 ubiE/COQ5 methyltransferase family AdoMet_MTase PF07757.8 KPI45563.1 - 0.0058 16.7 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase N6_N4_Mtase PF01555.13 KPI45563.1 - 0.014 14.9 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 0 DNA methylase TPMT PF05724.6 KPI45563.1 - 0.093 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MetW PF07021.7 KPI45563.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MRP-L46 PF11788.3 KPI45564.1 - 6.6e-27 94.3 0.0 1.3e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 KPI45564.1 - 2.8e-05 23.7 0.1 6.9e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain Thioredoxin_7 PF13899.1 KPI45565.1 - 6.9e-15 54.8 0.0 1.4e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 KPI45565.1 - 4.7e-09 36.1 0.0 1.5e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.1 KPI45565.1 - 2.3e-07 30.1 0.0 5.2e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Thioredox_DsbH PF03190.10 KPI45565.1 - 0.00024 20.8 0.1 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.1 KPI45565.1 - 0.0014 18.7 0.0 0.003 17.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain DUF3176 PF11374.3 KPI45566.1 - 1.8e-29 101.8 2.9 2e-29 101.6 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) stn_TNFRSF12A PF12191.3 KPI45566.1 - 0.0088 16.0 0.0 0.038 14.0 0.0 2.0 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Peptidase_S10 PF00450.17 KPI45567.1 - 8.6e-55 186.5 1.9 1.8e-48 165.7 0.2 3.0 2 1 0 2 2 2 2 Serine carboxypeptidase Fungal_trans PF04082.13 KPI45568.1 - 8.8e-12 44.4 0.0 1.4e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain BATS PF06968.8 KPI45569.1 - 2e-29 101.2 0.0 6.2e-29 99.6 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 KPI45569.1 - 1e-14 55.0 0.1 1.8e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily DIOX_N PF14226.1 KPI45570.1 - 2.7e-26 92.3 0.3 5.1e-26 91.4 0.2 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KPI45570.1 - 2.4e-22 79.0 0.0 6.8e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 KPI45570.1 - 6.1e-18 64.6 0.1 1e-17 63.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAP3 PF10236.4 KPI45571.1 - 1.7e-72 244.0 0.0 2e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 KPI45571.1 - 0.00037 20.5 0.0 0.00074 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 KPI45571.1 - 0.014 14.3 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 KPI45571.1 - 0.028 14.3 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain MutS_V PF00488.16 KPI45571.1 - 0.082 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 MutS domain V Arch_ATPase PF01637.13 KPI45571.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Cupin_2 PF07883.6 KPI45572.1 - 5.9e-08 32.1 0.0 1.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KPI45572.1 - 0.045 13.1 0.0 0.096 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF1857 PF08982.6 KPI45573.1 - 2.4e-30 105.1 0.0 2.8e-30 104.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) NIPSNAP PF07978.8 KPI45575.1 - 7.3e-28 96.5 0.4 1.5e-24 85.8 0.0 2.0 2 0 0 2 2 2 2 NIPSNAP HhH-GPD PF00730.20 KPI45576.1 - 1.7e-07 31.4 0.0 3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein AA_permease_2 PF13520.1 KPI45577.1 - 2.6e-57 194.2 54.3 3.1e-57 194.0 37.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KPI45577.1 - 1.6e-22 79.5 43.7 2.2e-22 79.0 30.3 1.1 1 0 0 1 1 1 1 Amino acid permease PDR_CDR PF06422.7 KPI45577.1 - 0.19 11.3 1.1 0.5 10.0 0.1 2.3 2 0 0 2 2 2 0 CDR ABC transporter YlaC PF10777.4 KPI45577.1 - 7.6 6.0 7.7 1.6 8.2 0.0 2.9 3 0 0 3 3 3 0 Inner membrane protein YlaC Oxysterol_BP PF01237.13 KPI45578.1 - 1.4e-73 247.3 0.0 1.9e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Peptidase_M24 PF00557.19 KPI45579.1 - 1.4e-46 158.6 0.1 1.7e-46 158.3 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KPI45579.1 - 0.00032 20.5 6.5 0.00073 19.3 4.5 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KPI45579.1 - 0.12 12.0 5.0 0.22 11.2 3.4 1.5 1 0 0 1 1 1 0 HIT zinc finger ATP-cone PF03477.11 KPI45579.1 - 0.16 12.4 0.0 19 5.7 0.0 2.2 2 0 0 2 2 2 0 ATP cone domain Fungal_trans_2 PF11951.3 KPI45581.1 - 1.3e-09 37.1 0.5 3.1e-05 22.7 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Tim17 PF02466.14 KPI45582.1 - 9.1e-29 100.1 5.6 1.2e-28 99.7 3.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3042 PF11240.3 KPI45582.1 - 0.11 12.3 3.4 0.12 12.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) DUF2953 PF11167.3 KPI45582.1 - 0.42 10.5 2.1 4.2 7.3 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) zf-RING_2 PF13639.1 KPI45583.1 - 5.9e-08 32.4 11.2 1.1e-05 25.1 4.7 2.4 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 KPI45583.1 - 0.0005 19.6 4.0 0.0074 15.9 1.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI45583.1 - 0.00059 19.8 7.9 0.0048 16.8 3.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI45583.1 - 0.0012 18.5 8.0 0.0021 17.7 3.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KPI45583.1 - 0.0097 15.5 7.5 0.028 14.0 3.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KPI45583.1 - 0.054 13.5 5.6 0.68 10.0 3.0 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger FANCL_C PF11793.3 KPI45583.1 - 4.4 7.3 11.2 14 5.7 4.1 2.8 3 0 0 3 3 3 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 KPI45583.1 - 5.4 6.9 7.3 19 5.2 2.0 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING SWIB PF02201.13 KPI45585.1 - 3.3e-25 87.5 0.0 5.9e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 KPI45585.1 - 5.8e-10 38.7 0.1 1.2e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 DEK C terminal domain CTF_NFI PF00859.13 KPI45585.1 - 0.013 15.3 2.1 0.016 14.9 1.4 1.3 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region XRCC4 PF06632.7 KPI45585.1 - 0.024 13.5 7.8 0.03 13.1 5.4 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Macoilin PF09726.4 KPI45585.1 - 0.29 9.3 5.0 0.35 9.0 3.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Herpes_DNAp_acc PF04929.7 KPI45585.1 - 0.91 8.4 8.3 1.3 7.8 5.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Phyto_Pns9_10 PF05878.6 KPI45585.1 - 1.2 8.1 4.0 0.95 8.4 1.6 1.7 1 1 1 2 2 2 0 Phytoreovirus nonstructural protein Pns9/Pns10 Glyco_hydro_8 PF01270.12 KPI45586.1 - 0.2 10.3 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 tRNA-synt_2 PF00152.15 KPI45588.1 - 3.7e-85 285.6 0.0 1.5e-46 158.7 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KPI45588.1 - 0.0022 17.6 0.1 0.0055 16.3 0.1 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 KPI45588.1 - 0.031 13.4 0.0 0.18 11.0 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) LUC7 PF03194.10 KPI45589.1 - 5.2e-56 190.0 0.7 4.5e-31 108.2 0.1 2.0 1 1 1 2 2 2 2 LUC7 N_terminus Tom37_C PF11801.3 KPI45590.1 - 1.5e-25 89.9 0.0 3e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 KPI45590.1 - 1.9e-23 82.4 0.8 8.7e-22 77.1 0.0 3.4 4 0 0 4 4 4 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 KPI45590.1 - 0.0033 17.2 0.8 0.01 15.7 0.2 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KPI45590.1 - 0.0037 17.6 0.3 0.012 16.0 0.2 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KPI45590.1 - 0.025 14.5 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_16 PF00722.16 KPI45591.1 - 5.4e-41 139.9 4.9 9.8e-41 139.0 3.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HemX PF04375.9 KPI45591.1 - 0.051 12.1 0.3 0.077 11.5 0.2 1.2 1 0 0 1 1 1 0 HemX Ecl1 PF12855.2 KPI45593.1 - 8.7e-16 56.9 2.5 1.4e-15 56.3 1.8 1.3 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 KPI45593.1 - 0.0016 18.2 1.8 0.0028 17.5 1.2 1.4 1 0 0 1 1 1 1 MYND finger DUF581 PF04570.9 KPI45593.1 - 0.0046 16.2 1.5 0.0092 15.2 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF581) DUF2256 PF10013.4 KPI45593.1 - 0.9 9.3 4.1 0.74 9.6 0.6 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Peptidase_M24 PF00557.19 KPI45594.1 - 1.3e-11 44.4 0.0 2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Fungal_trans_2 PF11951.3 KPI45595.1 - 5.3e-62 209.6 0.1 8e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KPI45595.1 - 3.6e-09 36.3 8.6 6.1e-09 35.6 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UvrD_C PF13361.1 KPI45596.1 - 9.4e-74 248.9 0.1 1.9e-73 247.9 0.0 1.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KPI45596.1 - 6.1e-61 206.4 0.3 6.1e-61 206.4 0.2 2.3 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KPI45596.1 - 2.7e-13 49.9 0.0 7.1e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KPI45596.1 - 4.8e-13 48.6 0.2 2.5e-12 46.3 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 KPI45596.1 - 7.4e-06 25.6 0.9 0.013 15.0 0.0 3.5 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KPI45596.1 - 1.5e-05 24.6 0.0 0.0019 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KPI45596.1 - 4.2e-05 23.0 0.1 0.0032 16.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KPI45596.1 - 0.00058 20.0 0.6 0.37 10.9 0.2 2.6 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 KPI45596.1 - 0.0014 18.2 2.8 0.002 17.7 0.2 2.3 2 1 0 2 2 2 1 AAA domain ZZ PF00569.12 KPI45597.1 - 6.2e-12 44.8 9.7 1.1e-11 44.0 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 KPI45597.1 - 7.1e-11 40.6 1.5 0.00013 21.0 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KPI45597.1 - 1.6e-10 40.9 2.7 6.3e-10 39.0 1.9 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KPI45597.1 - 3e-09 35.9 4.1 0.00012 21.6 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KPI45597.1 - 6.4e-07 28.9 1.1 6.4e-05 22.4 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 KPI45597.1 - 0.02 14.2 1.7 0.27 10.6 0.1 2.9 2 0 0 2 2 2 0 EF hand C1_3 PF07649.7 KPI45597.1 - 3.5 7.7 12.2 6.4 6.9 8.5 1.5 1 0 0 1 1 1 0 C1-like domain zf-B_box PF00643.19 KPI45597.1 - 6.2 6.7 9.8 11 5.9 6.8 1.4 1 0 0 1 1 1 0 B-box zinc finger Cyclase PF04199.8 KPI45598.1 - 2.6e-13 50.0 0.1 4.2e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase HATPase_c_3 PF13589.1 KPI45600.1 - 9.2e-07 28.5 0.0 1.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KPI45600.1 - 0.0045 16.6 0.0 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HET PF06985.6 KPI45601.1 - 2.3e-21 76.4 7.5 2.8e-18 66.3 1.3 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.14 KPI45602.1 - 3.4e-81 273.0 0.0 5.2e-81 272.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KPI45602.1 - 1.5e-41 141.8 0.0 2.7e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 KPI45602.1 - 5.5e-06 25.1 0.1 9.6e-06 24.3 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KPI45602.1 - 7.2e-06 25.2 0.0 0.00031 19.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KPI45602.1 - 2.3e-05 24.3 0.2 6.8e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI45602.1 - 8e-05 21.6 0.2 0.00012 21.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI45602.1 - 0.00039 19.4 0.0 0.0007 18.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KPI45602.1 - 0.00063 18.9 0.1 0.001 18.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KPI45602.1 - 0.015 14.2 0.1 0.024 13.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KPI45602.1 - 0.027 13.3 0.2 0.044 12.6 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KPI45602.1 - 0.035 14.1 0.2 0.064 13.3 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI45602.1 - 0.054 13.5 0.1 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Sugar_tr PF00083.19 KPI45603.1 - 9e-74 248.6 24.7 1.1e-73 248.4 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI45603.1 - 1.9e-19 69.6 40.1 6.4e-12 44.8 21.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.1 KPI45603.1 - 0.16 12.3 1.0 0.21 11.9 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DHH PF01368.15 KPI45604.1 - 2.8e-09 36.7 0.0 5.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 DHH family DHHA2 PF02833.9 KPI45604.1 - 8.4e-05 22.7 0.4 0.00027 21.1 0.3 2.0 1 1 0 1 1 1 1 DHHA2 domain Thioesterase PF00975.15 KPI45604.1 - 0.099 12.8 0.0 0.57 10.3 0.0 2.3 1 1 0 1 1 1 0 Thioesterase domain Orn_Arg_deC_N PF02784.11 KPI45605.1 - 6.4e-74 248.3 0.0 9.3e-74 247.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KPI45605.1 - 3.6e-30 104.0 0.0 6.5e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain MFS_1 PF07690.11 KPI45606.1 - 5.8e-51 173.2 33.2 5.8e-51 173.2 23.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI45606.1 - 4.8e-09 35.3 24.3 1e-07 30.9 16.8 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter SMN PF06003.7 KPI45606.1 - 0.00042 19.5 0.3 0.00063 18.9 0.2 1.1 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) RNB PF00773.14 KPI45607.1 - 4.4e-93 312.1 0.0 6.7e-93 311.5 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 KPI45607.1 - 1.8e-13 50.7 0.1 5.8e-13 49.0 0.1 1.9 1 0 0 1 1 1 1 PIN domain Myc_N PF01056.13 KPI45607.1 - 0.27 10.3 3.6 0.26 10.4 1.5 1.6 2 0 0 2 2 2 0 Myc amino-terminal region RRM_1 PF00076.17 KPI45610.1 - 9.4e-18 63.6 0.1 1.6e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI45610.1 - 3e-12 46.3 0.0 6.1e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI45610.1 - 0.0012 18.6 0.5 0.0022 17.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KPI45610.1 - 0.048 13.1 0.9 0.096 12.1 0.1 1.8 2 0 0 2 2 2 0 Ribonuclease B OB domain PAT1 PF09770.4 KPI45610.1 - 1.2 7.3 11.8 1.4 7.1 8.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DSBA PF01323.15 KPI45611.1 - 3.9e-15 55.9 0.0 1.2e-14 54.3 0.0 1.7 1 1 0 1 1 1 1 DSBA-like thioredoxin domain DUF372 PF04036.7 KPI45611.1 - 0.08 12.4 0.2 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF372) Pescadillo_N PF06732.6 KPI45612.1 - 7.9e-112 373.1 0.4 7.9e-112 373.1 0.3 2.0 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 KPI45612.1 - 5.9e-09 35.9 0.0 2.1e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF3824 PF12868.2 KPI45612.1 - 2.3 9.1 7.6 0.45 11.4 2.0 2.2 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) PEX11 PF05648.9 KPI45612.1 - 4.4 6.5 5.7 22 4.2 0.0 2.4 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Cep57_MT_bd PF06657.8 KPI45613.1 - 0.0056 16.6 0.4 0.0056 16.6 0.3 3.0 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 CH PF00307.26 KPI45614.1 - 7.7e-65 215.7 0.0 1.6e-19 69.9 0.1 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KPI45614.1 - 1.4e-06 28.3 1.2 5.7e-06 26.3 0.4 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KPI45614.1 - 0.00082 18.5 0.5 0.48 9.8 0.0 3.5 3 0 0 3 3 3 1 EF hand CAMSAP_CH PF11971.3 KPI45614.1 - 0.0019 17.8 0.0 2 8.1 0.0 3.5 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_6 PF13405.1 KPI45614.1 - 0.0056 16.4 0.4 0.061 13.2 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain Abhydrolase_3 PF07859.8 KPI45616.1 - 6.2e-41 140.2 0.0 8.3e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KPI45616.1 - 3.4e-07 29.2 0.0 4.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KPI45616.1 - 9.1e-06 25.4 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KPI45616.1 - 0.0004 19.2 0.3 0.007 15.1 0.2 2.0 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KPI45616.1 - 0.013 14.7 0.0 0.17 11.0 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 KPI45616.1 - 0.033 13.0 0.0 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme UPF0175 PF03683.8 KPI45616.1 - 0.05 13.0 0.0 0.091 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) AXE1 PF05448.7 KPI45616.1 - 0.14 10.6 0.0 0.58 8.5 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Sec10 PF07393.6 KPI45617.1 - 2.8e-131 439.0 0.0 9.5e-131 437.2 0.0 1.7 2 0 0 2 2 2 1 Exocyst complex component Sec10 F-box PF00646.28 KPI45617.1 - 0.00013 21.4 0.1 0.00029 20.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KPI45617.1 - 0.00084 19.0 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like DUF2097 PF09870.4 KPI45617.1 - 0.019 15.0 1.0 2.4 8.2 0.0 3.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2097) TUG-UBL1 PF11470.3 KPI45618.1 - 1.1e-25 89.2 0.0 2.1e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 GLUT4 regulating protein TUG DUF1499 PF07386.6 KPI45618.1 - 0.09 12.9 0.4 0.26 11.4 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1499) CorA PF01544.13 KPI45620.1 - 1.9e-15 56.6 0.2 3.2e-15 55.9 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ribosomal_S15 PF00312.17 KPI45620.1 - 0.13 12.0 0.4 0.5 10.1 0.1 2.0 2 0 0 2 2 2 0 Ribosomal protein S15 Fungal_trans_2 PF11951.3 KPI45621.1 - 4.9e-14 51.7 3.9 4.2e-12 45.3 2.6 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.7 KPI45622.1 - 1.3e-25 89.2 0.8 2.8e-25 88.1 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI45622.1 - 2.9e-19 68.9 1.4 4.2e-19 68.3 1.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI45622.1 - 0.007 17.2 0.5 0.013 16.4 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1967 PF09269.6 KPI45622.1 - 0.12 12.0 0.1 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Abhydrolase_4 PF08386.5 KPI45623.1 - 1e-16 60.7 0.0 1.8e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KPI45623.1 - 1.2e-09 38.0 0.1 2.7e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI45623.1 - 3.4e-07 30.3 0.0 6.7e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF4411 PF14367.1 KPI45623.1 - 0.051 13.2 0.1 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) E1-E2_ATPase PF00122.15 KPI45624.1 - 4.9e-64 215.5 5.5 4.9e-64 215.5 3.8 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KPI45624.1 - 1.1e-45 155.4 5.7 1.2e-45 155.2 2.9 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KPI45624.1 - 7.1e-34 118.1 0.0 3.8e-33 115.7 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KPI45624.1 - 4.5e-20 71.4 0.0 9.6e-20 70.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KPI45624.1 - 1.8e-18 65.7 0.0 4.8e-18 64.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KPI45624.1 - 1.8e-17 64.1 0.0 1.2e-16 61.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KPI45624.1 - 1.1e-09 38.3 1.9 1.5e-06 27.9 1.0 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KPI45624.1 - 0.0054 16.9 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KPI45624.1 - 0.066 13.1 0.0 0.25 11.2 0.0 2.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Proteasome_A_N PF10584.4 KPI45624.1 - 0.087 12.1 0.2 0.22 10.9 0.1 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Peptidase_S8 PF00082.17 KPI45625.1 - 3.1e-23 82.3 0.1 4.5e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Subtilase family TPR_12 PF13424.1 KPI45625.1 - 1.2e-06 28.3 1.6 0.06 13.2 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 KPI45625.1 - 0.0023 17.8 0.3 0.22 11.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KPI45625.1 - 0.011 16.1 0.1 0.073 13.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Calponin PF00402.13 KPI45625.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Calponin family repeat Iso_dh PF00180.15 KPI45627.1 - 1.1e-83 281.0 0.0 1.3e-83 280.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase p450 PF00067.17 KPI45628.1 - 1.3e-52 178.8 0.0 2e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF4196 PF13846.1 KPI45628.1 - 0.19 12.0 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) SGL PF08450.7 KPI45629.1 - 1.2e-23 83.7 0.0 2.6e-23 82.6 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 KPI45629.1 - 0.036 14.0 3.8 4.1 7.5 0.0 4.0 4 0 0 4 4 4 0 NHL repeat Arylesterase PF01731.15 KPI45629.1 - 0.077 12.9 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Arylesterase PQQ_3 PF13570.1 KPI45629.1 - 0.45 10.8 5.1 3.7 7.9 0.1 4.0 5 0 0 5 5 5 0 PQQ-like domain TraG-D_C PF12696.2 KPI45630.1 - 0.029 14.2 1.8 0.053 13.3 1.2 1.4 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Kei1 PF08552.6 KPI45630.1 - 0.38 10.3 4.2 0.11 12.0 1.0 1.6 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 LPP20 PF02169.11 KPI45630.1 - 2.7 8.1 9.2 0.13 12.3 2.4 1.7 2 0 0 2 2 2 0 LPP20 lipoprotein Macoilin PF09726.4 KPI45630.1 - 8.5 4.5 8.5 11 4.1 5.9 1.1 1 0 0 1 1 1 0 Transmembrane protein tRNA-synt_1g PF09334.6 KPI45631.1 - 1.7e-12 46.7 0.0 2.7e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KPI45631.1 - 9.4e-06 23.9 0.1 1.9e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KPI45631.1 - 9.6e-05 22.1 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Saf-Nte_pilin PF09460.5 KPI45631.1 - 0.091 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Saf-pilin pilus formation protein Filament PF00038.16 KPI45632.1 - 0.0017 17.8 3.6 0.0017 17.8 2.5 1.8 2 0 0 2 2 2 1 Intermediate filament protein EMP24_GP25L PF01105.19 KPI45632.1 - 0.057 13.1 0.9 0.21 11.3 0.6 1.9 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD TACC PF05010.9 KPI45632.1 - 0.8 9.4 8.0 2.8 7.6 4.8 2.4 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Aa_trans PF01490.13 KPI45633.1 - 3.7e-28 98.1 24.4 5.4e-28 97.5 16.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_C69 PF03577.10 KPI45635.1 - 2e-27 96.1 0.0 2.6e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.11 KPI45635.1 - 0.031 13.7 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Sugar_tr PF00083.19 KPI45636.1 - 7e-71 239.1 23.4 8.2e-71 238.8 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI45636.1 - 3.1e-17 62.3 29.7 3.8e-17 62.0 16.1 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KPI45636.1 - 0.0076 16.0 5.3 0.47 10.2 0.3 3.4 3 0 0 3 3 3 2 MFS_1 like family Mito_carr PF00153.22 KPI45637.1 - 5e-42 141.5 2.3 7.3e-15 54.4 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein GDE_C PF06202.9 KPI45637.1 - 0.14 10.8 0.0 4.1 6.0 0.0 2.3 2 1 0 2 2 2 0 Amylo-alpha-1,6-glucosidase Amidase PF01425.16 KPI45639.1 - 3.5e-93 312.8 0.0 4.1e-93 312.6 0.0 1.0 1 0 0 1 1 1 1 Amidase RQC PF09382.5 KPI45641.1 - 3.9e-25 87.6 0.4 1.2e-24 86.0 0.3 1.9 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 KPI45641.1 - 2.3e-20 72.7 0.2 6.4e-20 71.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI45641.1 - 8.7e-20 70.3 0.0 9.2e-18 63.8 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI45641.1 - 6e-05 22.9 0.2 0.00037 20.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Peptidase_C23 PF05379.6 KPI45641.1 - 0.14 12.1 0.1 0.71 9.8 0.0 2.1 1 1 1 2 2 2 0 Carlavirus endopeptidase HTH_9 PF08221.6 KPI45641.1 - 0.16 11.8 0.5 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Tmemb_55A PF09788.4 KPI45642.1 - 0.041 13.0 0.0 0.082 12.0 0.0 1.6 2 0 0 2 2 2 0 Transmembrane protein 55A Bac_export_3 PF01313.14 KPI45642.1 - 0.23 11.1 1.4 0.33 10.6 0.9 1.2 1 0 0 1 1 1 0 Bacterial export proteins, family 3 ADH_N PF08240.7 KPI45643.1 - 1.2e-28 99.0 0.8 1.9e-28 98.4 0.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KPI45643.1 - 2.5e-07 30.2 0.0 0.00045 19.7 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KPI45643.1 - 0.0028 17.2 0.1 0.0072 15.9 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Methyltransf_18 PF12847.2 KPI45643.1 - 0.061 13.9 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Amidohydro_1 PF01979.15 KPI45645.1 - 3.9e-33 115.5 0.0 5e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KPI45645.1 - 5.7e-08 32.3 0.0 6.8e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KPI45645.1 - 1.7e-07 31.5 0.4 3.1e-06 27.4 0.2 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KPI45645.1 - 0.0032 17.2 0.0 0.0081 15.9 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 KPI45645.1 - 0.013 14.4 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase TauD PF02668.11 KPI45647.1 - 8.4e-20 71.5 0.0 1.1e-19 71.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_114 PF03537.8 KPI45648.1 - 1.6e-17 62.9 0.4 2.8e-17 62.2 0.3 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 ETRAMP PF09716.5 KPI45648.1 - 0.08 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Tir_receptor_C PF07489.6 KPI45648.1 - 0.086 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus CENP-Q PF13094.1 KPI45649.1 - 0.0045 17.0 2.4 0.011 15.8 1.6 1.6 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Jnk-SapK_ap_N PF09744.4 KPI45649.1 - 0.071 13.1 1.0 0.13 12.2 0.7 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF2383 PF09537.5 KPI45649.1 - 0.23 11.7 3.3 15 5.8 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF2383) AAA PF00004.24 KPI45650.1 - 1.3e-55 187.1 0.0 2.2e-43 147.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KPI45650.1 - 5.6e-28 96.8 0.2 1.1e-27 95.8 0.2 1.5 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 KPI45650.1 - 3.7e-13 49.8 1.9 3.3e-07 30.4 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 KPI45650.1 - 1.5e-07 32.2 0.0 0.0099 16.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KPI45650.1 - 2.7e-07 30.5 0.0 0.013 15.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 KPI45650.1 - 2.7e-07 30.3 0.2 0.00028 20.6 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_2 PF07724.9 KPI45650.1 - 1.1e-06 28.7 0.0 0.059 13.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KPI45650.1 - 4.8e-06 26.3 0.0 0.05 13.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KPI45650.1 - 1.7e-05 25.0 0.5 0.36 10.9 0.0 3.5 2 2 1 3 3 3 2 AAA domain AAA_25 PF13481.1 KPI45650.1 - 7.3e-05 22.2 1.5 2.4 7.5 0.1 4.2 2 2 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 KPI45650.1 - 0.00016 21.1 0.0 0.47 9.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.7 KPI45650.1 - 0.00016 20.7 0.0 0.014 14.4 0.0 2.6 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KPI45650.1 - 0.00016 20.5 0.0 0.14 10.8 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 KPI45650.1 - 0.00024 21.3 0.0 0.08 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KPI45650.1 - 0.00027 20.6 0.0 1.1 9.0 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 KPI45650.1 - 0.00034 20.5 0.0 0.91 9.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KPI45650.1 - 0.00065 19.8 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.7 KPI45650.1 - 0.0012 18.0 0.0 0.75 8.8 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin UPF0079 PF02367.12 KPI45650.1 - 0.0061 16.1 0.1 0.24 11.0 0.0 2.9 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 KPI45650.1 - 0.0096 15.8 0.0 3.4 7.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KPI45650.1 - 0.013 14.7 0.0 0.69 9.0 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 KPI45650.1 - 0.034 13.8 0.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 NTPase APS_kinase PF01583.15 KPI45650.1 - 0.04 13.5 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase SKI PF01202.17 KPI45650.1 - 0.067 13.0 0.0 4.6 7.0 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase KTI12 PF08433.5 KPI45650.1 - 0.076 12.2 0.0 0.57 9.3 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Vps4_C PF09336.5 KPI45650.1 - 0.081 12.8 0.1 4 7.3 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain DUF2075 PF09848.4 KPI45650.1 - 0.089 11.7 0.0 4.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 KPI45650.1 - 0.1 11.5 0.1 2.9 6.7 0.0 2.7 2 1 1 3 3 3 0 KAP family P-loop domain KaiC PF06745.8 KPI45650.1 - 0.16 11.0 0.0 9.5 5.2 0.0 2.3 2 0 0 2 2 2 0 KaiC Arch_ATPase PF01637.13 KPI45650.1 - 0.26 10.9 0.0 47 3.5 0.0 2.9 2 1 1 3 3 3 0 Archaeal ATPase RasGEF PF00617.14 KPI45651.1 - 1.4e-54 184.7 1.9 2.8e-54 183.7 1.3 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KPI45651.1 - 2e-15 56.7 0.0 1.4e-14 54.0 0.0 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 KPI45651.1 - 7.5e-06 25.2 0.0 1.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KPI45651.1 - 7.7e-06 25.4 0.0 2.1e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain CHASE3 PF05227.8 KPI45651.1 - 0.031 13.9 0.6 0.16 11.6 0.4 2.3 1 0 0 1 1 1 0 CHASE3 domain Pox_F11 PF04943.7 KPI45651.1 - 0.046 12.5 2.2 0.076 11.8 1.5 1.3 1 0 0 1 1 1 0 Poxvirus F11 protein tRNA-synt_1b PF00579.20 KPI45652.1 - 1.2e-69 234.6 0.0 1.6e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 KPI45652.1 - 0.0004 19.7 0.0 0.00082 18.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain Polysacc_deac_1 PF01522.16 KPI45653.1 - 0.0011 18.6 0.0 0.0024 17.4 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Epimerase PF01370.16 KPI45654.1 - 3.2e-08 33.2 0.0 5.8e-06 25.9 0.0 2.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KPI45654.1 - 0.00043 19.2 0.0 0.0013 17.7 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein DUF3077 PF11275.3 KPI45654.1 - 0.089 12.7 0.3 0.85 9.6 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3077) Amino_oxidase PF01593.19 KPI45655.1 - 6.6e-49 167.1 0.1 9.3e-49 166.6 0.1 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KPI45655.1 - 6.4e-17 61.3 0.5 1.3e-16 60.3 0.1 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI45655.1 - 2.3e-08 33.2 1.1 3.6e-08 32.6 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI45655.1 - 4.5e-08 32.3 0.4 1.3e-07 30.8 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KPI45655.1 - 3.4e-06 26.3 0.3 5.7e-06 25.6 0.2 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KPI45655.1 - 3.9e-06 26.8 0.0 6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI45655.1 - 8.1e-06 24.9 0.0 0.0036 16.2 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KPI45655.1 - 1.4e-05 25.2 0.0 0.00021 21.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KPI45655.1 - 1.8e-05 23.9 0.5 2.6e-05 23.4 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KPI45655.1 - 9.6e-05 21.6 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KPI45655.1 - 0.00013 20.5 0.2 0.00036 19.1 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KPI45655.1 - 0.00078 18.4 0.7 0.0013 17.6 0.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KPI45655.1 - 0.005 17.2 2.0 0.0092 16.3 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KPI45655.1 - 0.088 12.3 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aldedh PF00171.17 KPI45657.1 - 1.7e-184 613.5 0.9 1.9e-184 613.3 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KPI45657.1 - 0.038 13.2 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Pkinase PF00069.20 KPI45658.1 - 4.1e-61 206.4 0.1 5.6e-55 186.2 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KPI45658.1 - 5.5e-41 140.3 0.0 5.5e-39 133.7 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KPI45658.1 - 0.0065 15.4 0.0 3.1 6.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like PAT1 PF09770.4 KPI45658.1 - 2.8 6.0 23.3 4 5.5 16.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDK2AP PF09806.4 KPI45658.1 - 3.3 7.8 14.8 1.9 8.7 3.8 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein HET PF06985.6 KPI45659.1 - 2.7e-20 72.9 0.0 5.2e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Proteasome PF00227.21 KPI45660.1 - 1.4e-27 96.1 0.0 1.7e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Zn_clus PF00172.13 KPI45661.1 - 0.0047 16.7 11.0 0.0084 15.9 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rootletin PF15035.1 KPI45661.1 - 0.21 11.5 0.3 7.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion HAD PF12710.2 KPI45662.1 - 9.1e-09 35.7 0.0 1.3e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KPI45662.1 - 0.00055 19.1 0.0 0.0033 16.6 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.7 KPI45662.1 - 0.00084 18.7 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.21 KPI45662.1 - 0.064 13.6 0.0 0.83 10.0 0.0 2.2 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase PAD_porph PF04371.10 KPI45663.1 - 2.9e-82 276.3 0.0 3.3e-82 276.1 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.12 KPI45663.1 - 0.0048 16.0 0.0 0.01 14.9 0.0 1.6 1 1 0 1 1 1 1 Amidinotransferase SNF2_N PF00176.18 KPI45664.1 - 3.5e-52 177.0 0.0 7.5e-52 175.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 KPI45664.1 - 1.1e-09 37.8 8.9 2.3e-09 36.7 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KPI45664.1 - 7.3e-09 35.3 9.3 1.8e-08 34.0 6.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KPI45664.1 - 7.1e-08 32.0 7.2 1.6e-07 30.8 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI45664.1 - 3.1e-07 30.2 9.5 7.8e-07 29.0 6.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI45664.1 - 1.5e-06 27.8 8.5 3.8e-06 26.5 5.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KPI45664.1 - 1.3e-05 25.2 5.6 3.6e-05 23.7 3.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KPI45664.1 - 0.0015 18.3 7.9 0.0031 17.3 5.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KPI45664.1 - 0.0036 16.9 6.7 0.011 15.4 4.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Baculo_IE-1 PF05290.6 KPI45664.1 - 0.025 14.3 0.3 0.058 13.1 0.2 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.1 KPI45664.1 - 0.12 11.9 4.9 0.29 10.7 3.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KPI45664.1 - 0.22 11.1 7.9 0.53 9.9 5.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 KPI45664.1 - 0.98 8.9 6.3 2.3 7.7 4.4 1.6 1 0 0 1 1 1 0 P-11 zinc finger DAO PF01266.19 KPI45665.1 - 3.6e-13 49.1 6.2 8.8e-13 47.8 4.3 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase DUF3328 PF11807.3 KPI45666.1 - 1.1e-15 57.9 0.5 6.9e-15 55.3 0.3 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) UAF_Rrn10 PF05234.6 KPI45667.1 - 8.7e-05 22.5 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Stimulus_sens_1 PF13756.1 KPI45667.1 - 0.055 13.8 0.1 0.095 13.0 0.0 1.4 1 0 0 1 1 1 0 Stimulus-sensing domain Erv26 PF04148.8 KPI45668.1 - 4.2e-85 284.4 0.0 5e-85 284.1 0.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 A_deaminase PF00962.17 KPI45669.1 - 8.6e-37 126.7 0.0 1.3e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase KdpA PF03814.10 KPI45669.1 - 0.0029 15.6 0.1 0.0045 15.0 0.0 1.1 1 0 0 1 1 1 1 Potassium-transporting ATPase A subunit RRS1 PF04939.7 KPI45671.1 - 9e-43 145.5 0.2 1.1e-42 145.3 0.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Sld5 PF05916.6 KPI45673.1 - 0.00039 20.6 0.0 0.00065 19.9 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Cyclin_N PF00134.18 KPI45674.1 - 9.7e-36 122.1 0.3 2e-35 121.1 0.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KPI45674.1 - 2e-07 30.9 0.6 7.7e-07 29.0 0.4 2.0 1 1 0 1 1 1 1 Cyclin, C-terminal domain ADH_zinc_N PF00107.21 KPI45676.1 - 1.6e-21 76.2 0.5 2.5e-21 75.5 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI45676.1 - 2.7e-14 54.1 0.0 6.5e-14 52.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI45676.1 - 4.1e-11 42.5 0.0 1.2e-10 41.1 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KPI45676.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain YTH PF04146.10 KPI45677.1 - 1.8e-53 179.8 0.0 2.9e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 KPI45677.1 - 4.1e-09 35.9 0.0 7.4e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI45677.1 - 3e-07 30.3 0.0 6.1e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI45677.1 - 8.9e-05 22.2 0.3 0.0018 18.0 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trm112p PF03966.11 KPI45678.1 - 1.1e-10 41.6 0.0 2.8e-10 40.4 0.0 1.6 1 1 0 1 1 1 1 Trm112p-like protein A2L_zn_ribbon PF08792.5 KPI45678.1 - 0.024 14.0 0.1 0.043 13.2 0.1 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.7 KPI45678.1 - 0.036 13.3 0.1 0.078 12.3 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Sugar_tr PF00083.19 KPI45679.1 - 3.3e-75 253.3 15.7 3.9e-75 253.1 10.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI45679.1 - 6.6e-31 107.2 22.4 9.4e-25 87.0 10.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KPI45679.1 - 0.00061 18.1 2.8 0.0013 17.0 2.0 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ABC_tran PF00005.22 KPI45680.1 - 4.5e-27 95.0 0.1 7e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KPI45680.1 - 6.6e-09 36.1 0.0 0.00039 20.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KPI45680.1 - 4.4e-05 22.9 0.0 0.0074 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain RecA PF00154.16 KPI45680.1 - 8.5e-05 21.7 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_29 PF13555.1 KPI45680.1 - 0.00064 19.1 0.1 0.0014 18.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KPI45680.1 - 0.0016 17.6 0.0 0.0033 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 hEGF PF12661.2 KPI45680.1 - 0.0029 17.5 24.8 0.022 14.8 1.1 4.4 4 0 0 4 4 4 2 Human growth factor-like EGF AAA_16 PF13191.1 KPI45680.1 - 0.013 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.14 KPI45680.1 - 0.021 14.0 0.0 0.099 11.8 0.0 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KPI45680.1 - 0.021 14.9 0.0 0.042 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KPI45680.1 - 0.027 13.5 0.0 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 KPI45680.1 - 0.031 15.0 0.0 0.066 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 KPI45680.1 - 0.032 13.0 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 KPI45680.1 - 0.035 14.4 0.0 0.065 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KPI45680.1 - 0.072 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein FtsK_SpoIIIE PF01580.13 KPI45680.1 - 0.11 11.9 0.1 0.39 10.1 0.1 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 KPI45680.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KPI45680.1 - 0.12 12.0 0.1 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.20 KPI45680.1 - 0.15 11.5 0.1 0.5 9.8 0.0 1.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain EGF_2 PF07974.8 KPI45680.1 - 1.4 9.1 34.0 0.067 13.3 1.2 4.1 4 0 0 4 4 4 0 EGF-like domain E1_dh PF00676.15 KPI45681.1 - 3.4e-88 295.2 0.2 4.3e-88 294.9 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KPI45681.1 - 0.0063 16.0 0.2 0.019 14.5 0.1 1.8 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 KPI45681.1 - 0.16 10.8 0.0 0.42 9.5 0.0 1.6 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase N_methyl_2 PF13544.1 KPI45681.1 - 0.19 11.2 0.2 0.47 10.0 0.2 1.7 1 0 0 1 1 1 0 Type IV pilin N-term methylation site GFxxxE Ribosomal_S28e PF01200.13 KPI45682.1 - 2.7e-32 110.3 2.4 2.9e-32 110.2 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e APG6 PF04111.7 KPI45683.1 - 0.96 8.4 15.4 1.8 7.5 10.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 WD40 PF00400.27 KPI45684.1 - 1.7e-88 287.6 23.9 1.2e-15 56.6 0.4 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 KPI45684.1 - 1.6e-06 26.5 7.2 0.31 9.1 0.1 5.4 1 1 4 6 6 6 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 KPI45684.1 - 0.0004 19.5 0.4 1.7 7.6 0.0 3.6 4 1 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 KPI45684.1 - 0.0006 17.7 0.1 0.53 8.0 0.0 2.1 2 0 0 2 2 2 2 IKI3 family NLE PF08154.7 KPI45684.1 - 0.0028 17.6 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain TFIIIC_delta PF12657.2 KPI45684.1 - 0.006 16.3 7.3 5.1 6.7 0.0 5.8 4 2 1 5 5 5 1 Transcription factor IIIC subunit delta N-term PD40 PF07676.7 KPI45684.1 - 0.084 12.5 1.0 3.5 7.3 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 KPI45684.1 - 0.15 11.3 0.5 20 4.6 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PCI PF01399.22 KPI45685.1 - 5.7e-12 45.8 0.0 1.1e-10 41.7 0.0 2.8 2 1 0 2 2 2 1 PCI domain FlgM PF04316.8 KPI45685.1 - 0.12 12.2 3.8 0.41 10.6 2.6 1.9 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM GRP PF07172.6 KPI45685.1 - 1.5 9.3 11.4 3.6 8.1 7.9 1.6 1 0 0 1 1 1 0 Glycine rich protein family FimP PF09766.4 KPI45686.1 - 5e-21 75.1 9.9 8.5e-21 74.4 6.9 1.3 1 0 0 1 1 1 1 Fms-interacting protein Mnd1 PF03962.10 KPI45686.1 - 5.5 6.6 10.6 10 5.7 3.1 2.2 2 0 0 2 2 2 0 Mnd1 family CFEM PF05730.6 KPI45687.1 - 1.7e-08 34.1 15.2 1.7e-08 34.1 10.6 1.9 2 1 0 2 2 2 1 CFEM domain PAN_3 PF08277.7 KPI45687.1 - 0.23 11.1 2.7 22 4.7 1.7 2.3 2 0 0 2 2 2 0 PAN-like domain TIL PF01826.12 KPI45687.1 - 0.36 10.9 9.3 0.3 11.2 5.4 1.6 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain DNA_pol_viral_N PF00242.12 KPI45687.1 - 1.9 7.4 5.9 2.3 7.1 4.1 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Rifin_STEVOR PF02009.11 KPI45687.1 - 3.2 7.3 7.7 4.5 6.8 5.4 1.3 1 0 0 1 1 1 0 Rifin/stevor family DUF2217 PF10265.4 KPI45687.1 - 8.5 5.0 8.7 10 4.7 6.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 KPI45687.1 - 9.9 4.2 12.6 11 4.1 8.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Formyl_trans_N PF00551.14 KPI45688.1 - 1.1e-39 135.8 0.1 1.5e-39 135.3 0.1 1.2 1 0 0 1 1 1 1 Formyl transferase DUF1009 PF06230.6 KPI45688.1 - 0.003 16.9 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1009) Pyr_redox_3 PF13738.1 KPI45689.1 - 1.3e-24 87.3 0.0 2.3e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KPI45689.1 - 2e-13 49.3 0.0 3.6e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KPI45689.1 - 1e-12 47.8 0.0 1.5e-09 37.6 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI45689.1 - 1.2e-10 41.5 0.0 0.00024 21.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI45689.1 - 3.8e-08 32.6 0.2 8.5e-06 24.9 0.0 2.7 2 1 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.1 KPI45689.1 - 3.8e-07 29.3 0.0 1.8e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KPI45689.1 - 9.2e-07 29.1 0.3 0.0052 17.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KPI45689.1 - 2.1e-06 26.8 0.0 0.0025 16.7 0.0 3.6 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KPI45689.1 - 7.3e-05 21.7 0.0 0.0013 17.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 KPI45689.1 - 0.00037 20.2 0.7 0.093 12.4 0.1 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KPI45689.1 - 0.0006 19.5 0.0 0.036 13.7 0.0 2.5 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KPI45689.1 - 0.0019 17.6 1.1 1.6 8.1 0.0 2.9 3 1 1 4 4 4 2 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 KPI45689.1 - 0.0021 18.2 0.0 0.1 12.8 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 KPI45689.1 - 0.0022 17.1 0.2 0.44 9.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.14 KPI45689.1 - 0.019 14.1 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 KPI45689.1 - 0.019 13.4 0.9 2.4 6.5 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.15 KPI45689.1 - 0.02 14.9 0.0 2.9 7.9 0.0 2.5 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 KPI45689.1 - 0.042 13.7 0.0 0.31 10.8 0.0 2.4 4 0 0 4 4 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 KPI45689.1 - 0.059 13.3 0.4 7.3 6.6 0.0 3.0 3 0 0 3 3 3 0 TrkA-N domain GIDA PF01134.17 KPI45689.1 - 0.081 11.7 0.8 19 3.9 0.1 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 KPI45689.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 KPI45689.1 - 0.11 11.5 0.9 0.52 9.2 0.1 2.3 3 0 0 3 3 3 0 FAD binding domain ThiF PF00899.16 KPI45689.1 - 0.21 11.3 2.5 16 5.3 0.0 2.9 3 0 0 3 3 3 0 ThiF family NAD_binding_10 PF13460.1 KPI45689.1 - 0.36 10.8 1.1 3.6 7.5 0.0 2.4 3 0 0 3 3 2 0 NADH(P)-binding MFS_1 PF07690.11 KPI45690.1 - 9.7e-40 136.3 47.8 9.7e-40 136.3 33.2 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI45690.1 - 3e-06 26.0 13.8 3e-06 26.0 9.6 2.8 2 0 0 2 2 2 2 Sugar (and other) transporter DUF4448 PF14610.1 KPI45690.1 - 8.9 5.7 7.6 1.2 8.6 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4448) eIF2A PF08662.6 KPI45692.1 - 2.5e-41 141.5 4.8 3e-37 128.2 1.0 3.6 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 KPI45692.1 - 1.1e-07 31.3 0.0 2.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI45692.1 - 2.2e-06 27.5 0.0 4.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI45692.1 - 4.1e-06 26.5 0.0 9.6e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KPI45692.1 - 0.0025 17.6 0.0 13 5.9 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat p450 PF00067.17 KPI45693.1 - 5e-72 242.8 0.0 6.2e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MSA_2 PF00985.12 KPI45695.1 - 0.84 9.7 3.7 1.1 9.3 2.6 1.1 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family HD PF01966.17 KPI45696.1 - 0.00019 21.4 0.0 0.00036 20.5 0.0 1.5 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 KPI45696.1 - 0.052 12.8 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 HDOD domain Sugar_tr PF00083.19 KPI45697.1 - 9.4e-85 284.8 21.6 1.1e-84 284.6 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI45697.1 - 5.5e-25 87.8 47.1 1.9e-22 79.5 18.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily CoA_binding PF02629.14 KPI45698.1 - 1.7e-20 73.3 0.4 4.4e-20 72.0 0.3 1.7 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 KPI45698.1 - 7.4e-19 67.8 0.5 7.4e-19 67.8 0.4 2.1 3 0 0 3 3 3 1 CoA-ligase Succ_CoA_lig PF13607.1 KPI45698.1 - 1.2e-09 37.8 0.1 2.5e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain p450 PF00067.17 KPI45699.1 - 9.7e-54 182.5 0.0 2.1e-53 181.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 KPI45700.1 - 0.15 11.8 1.8 2.2 8.0 0.1 2.4 2 1 0 2 2 2 0 F-box-like MT0933_antitox PF14013.1 KPI45701.1 - 4.3 7.5 7.6 0.71 10.0 2.5 1.8 2 0 0 2 2 2 0 MT0933-like antitoxin protein DDHD PF02862.12 KPI45702.1 - 4.7e-63 213.0 4.4 6e-62 209.4 0.0 2.9 2 1 0 2 2 2 1 DDHD domain Abhydrolase_5 PF12695.2 KPI45702.1 - 0.045 13.5 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Cutinase PF01083.17 KPI45703.1 - 8.7e-51 172.1 0.3 1e-50 171.9 0.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KPI45703.1 - 0.0027 17.1 0.2 0.0047 16.3 0.1 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.11 KPI45703.1 - 0.015 14.7 0.1 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2974 PF11187.3 KPI45703.1 - 0.034 13.5 0.1 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) VirJ PF06057.6 KPI45703.1 - 0.059 13.1 0.0 0.087 12.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) p450 PF00067.17 KPI45704.1 - 4.5e-59 200.2 0.0 5.6e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_5 PF12695.2 KPI45705.1 - 6.9e-23 81.0 0.0 1e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KPI45705.1 - 2.8e-17 63.3 0.0 5.2e-16 59.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KPI45705.1 - 6.6e-09 34.7 0.0 0.028 12.9 0.0 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 KPI45705.1 - 1e-06 28.5 0.0 2.1e-06 27.4 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 KPI45705.1 - 1.3e-05 24.7 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KPI45705.1 - 6.4e-05 22.4 0.0 0.32 10.3 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase BAAT_C PF08840.6 KPI45705.1 - 0.00019 21.2 0.0 0.0051 16.5 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 KPI45705.1 - 0.00029 20.4 0.0 0.023 14.2 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold DUF818 PF05677.7 KPI45705.1 - 0.00041 19.2 0.0 0.00052 18.8 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.16 KPI45705.1 - 0.002 17.4 0.0 0.009 15.2 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2305 PF10230.4 KPI45705.1 - 0.007 15.8 0.1 0.3 10.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Peptidase_S15 PF02129.13 KPI45705.1 - 0.0072 15.7 0.1 0.58 9.5 0.0 2.3 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 KPI45705.1 - 0.016 14.4 0.0 0.39 9.9 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KPI45705.1 - 0.067 13.0 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase PGAP1 PF07819.8 KPI45705.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Cutinase PF01083.17 KPI45705.1 - 0.094 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.20 KPI45705.1 - 0.11 12.0 0.1 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LSM PF01423.17 KPI45706.1 - 2.9e-20 71.5 0.0 3.7e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain adh_short PF00106.20 KPI45707.1 - 1.8e-21 76.7 0.0 2.2e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI45707.1 - 4.1e-09 36.5 0.0 5.1e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI45707.1 - 4.2e-09 36.3 0.0 9.4e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KPI45707.1 - 1.3e-05 25.3 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KPI45707.1 - 0.0004 19.6 0.1 0.00058 19.0 0.1 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 KPI45707.1 - 0.00046 19.6 0.0 0.0008 18.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KPI45707.1 - 0.011 15.4 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_2 PF03446.10 KPI45707.1 - 0.052 13.3 0.0 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.12 KPI45707.1 - 0.069 12.0 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Saccharop_dh PF03435.13 KPI45707.1 - 0.12 11.3 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase ApbA PF02558.11 KPI45707.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HET PF06985.6 KPI45708.1 - 1.1e-27 96.9 0.0 2e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Stk19 PF10494.4 KPI45709.1 - 3.1e-54 184.0 0.7 3.6e-38 131.3 0.1 2.1 1 1 1 2 2 2 2 Serine-threonine protein kinase 19 Sugar_tr PF00083.19 KPI45710.1 - 3.3e-74 250.0 19.1 4.1e-74 249.7 13.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI45710.1 - 1.1e-20 73.6 42.6 2.4e-18 65.9 21.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Lig_chan PF00060.21 KPI45710.1 - 0.019 14.7 1.2 0.069 12.8 0.8 1.9 1 0 0 1 1 1 0 Ligand-gated ion channel Herpes_UL87 PF03043.9 KPI45710.1 - 0.27 9.5 0.3 0.39 9.0 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family MFS_1_like PF12832.2 KPI45710.1 - 0.27 11.0 6.5 4.7 7.0 0.0 3.5 3 0 0 3 3 3 0 MFS_1 like family SGL PF08450.7 KPI45711.1 - 1.9e-21 76.5 0.1 3.4e-20 72.4 0.1 2.1 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 KPI45711.1 - 0.0058 16.6 0.0 0.034 14.1 0.0 2.3 2 1 0 2 2 2 1 Strictosidine synthase PD40 PF07676.7 KPI45711.1 - 0.019 14.5 1.0 0.13 11.9 0.1 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 KPI45711.1 - 3.8 7.9 12.0 0.44 10.8 0.4 4.3 4 1 0 4 4 4 0 PQQ-like domain Polyketide_cyc PF03364.15 KPI45712.1 - 1.2e-10 41.4 0.0 1.4e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Abhydrolase_2 PF02230.11 KPI45713.1 - 1.5e-30 106.3 0.0 4.9e-21 75.1 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KPI45713.1 - 6.2e-08 32.5 0.0 1.1e-07 31.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KPI45713.1 - 0.00025 20.5 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KPI45713.1 - 0.00059 19.7 0.0 0.0067 16.3 0.1 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF2767 PF10965.3 KPI45713.1 - 0.065 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) ATP11 PF06644.6 KPI45714.1 - 4.7e-79 265.6 0.0 6.1e-79 265.2 0.0 1.1 1 0 0 1 1 1 1 ATP11 protein Proteasome PF00227.21 KPI45718.1 - 1.7e-40 138.3 0.0 2.1e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit RabGAP-TBC PF00566.13 KPI45720.1 - 2.7e-27 95.6 0.0 5.2e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain AAA PF00004.24 KPI45721.1 - 2.2e-14 53.7 0.0 3.4e-06 27.2 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 KPI45721.1 - 1.7e-06 27.8 0.1 1.7e-06 27.8 0.1 1.9 2 0 0 2 2 2 1 BCS1 N terminal AAA_17 PF13207.1 KPI45721.1 - 5.8e-05 23.9 0.1 0.00044 21.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KPI45721.1 - 0.0022 17.0 0.0 0.0052 15.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KPI45721.1 - 0.0063 16.8 0.8 0.089 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KPI45721.1 - 0.0094 15.6 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KPI45721.1 - 0.011 15.5 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KPI45721.1 - 0.012 14.9 0.1 0.038 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KPI45721.1 - 0.024 14.7 0.1 0.29 11.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 KPI45721.1 - 0.03 14.2 0.1 0.6 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 KPI45721.1 - 0.035 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KPI45721.1 - 0.056 13.0 0.0 0.18 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KPI45721.1 - 0.13 12.5 0.9 1.8 8.8 0.1 3.1 3 1 0 3 3 3 0 ABC transporter AAA_24 PF13479.1 KPI45721.1 - 0.95 9.0 6.8 3.9 7.0 0.3 2.8 3 0 0 3 3 3 0 AAA domain zf-MYND PF01753.13 KPI45722.1 - 1.6e-06 27.8 18.8 3e-06 26.9 13.0 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KPI45722.1 - 2 8.3 7.5 1.1 9.1 0.3 3.0 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Complex1_LYR PF05347.10 KPI45723.1 - 1.6e-12 47.0 0.6 3.5e-05 23.4 0.0 2.0 2 0 0 2 2 2 2 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KPI45723.1 - 1.7e-10 40.9 1.1 5.6e-10 39.2 0.8 1.7 1 1 0 1 1 1 1 Complex1_LYR-like INTS5_C PF14838.1 KPI45723.1 - 0.018 13.3 0.0 0.018 13.3 0.0 1.0 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus FAD_binding_3 PF01494.14 KPI45725.1 - 1.5e-15 57.1 0.0 1e-14 54.4 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI45725.1 - 1.9e-09 36.9 1.3 8e-06 24.9 0.2 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI45725.1 - 4.9e-06 26.4 0.4 1.4e-05 25.0 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KPI45725.1 - 4.4e-05 22.5 0.7 0.00011 21.1 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 KPI45725.1 - 0.0001 21.3 0.2 0.00016 20.6 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KPI45725.1 - 0.00047 20.1 0.6 0.0012 18.8 0.4 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI45725.1 - 0.0018 16.7 0.1 0.073 11.5 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KPI45725.1 - 0.0098 15.0 0.7 0.11 11.5 0.4 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KPI45725.1 - 0.012 16.0 0.0 0.067 13.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KPI45725.1 - 0.088 12.4 0.2 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lyase_1 PF00206.15 KPI45728.1 - 1.7e-90 303.3 0.0 2.9e-90 302.6 0.0 1.3 2 0 0 2 2 2 1 Lyase FumaraseC_C PF10415.4 KPI45728.1 - 1e-18 67.0 0.0 2.7e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus adh_short PF00106.20 KPI45729.1 - 1.9e-32 112.5 0.3 2.3e-32 112.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI45729.1 - 6.2e-13 48.8 0.2 9e-13 48.2 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KPI45729.1 - 5.1e-12 46.0 0.0 7e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KPI45729.1 - 0.019 14.3 0.2 0.037 13.4 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KPI45729.1 - 0.11 11.5 0.1 1.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 KPI45729.1 - 0.11 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TPR_11 PF13414.1 KPI45731.1 - 0.00024 20.6 0.1 0.035 13.7 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.1 KPI45731.1 - 0.018 15.2 0.3 0.22 11.8 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat CCDC92 PF14916.1 KPI45731.1 - 0.027 14.0 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Syntaxin-6_N PF09177.6 KPI45731.1 - 0.029 14.7 1.6 0.042 14.2 0.1 2.0 3 0 0 3 3 3 0 Syntaxin 6, N-terminal SpaB_C PF14028.1 KPI45731.1 - 0.064 12.8 0.6 0.078 12.5 0.4 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain Fungal_trans PF04082.13 KPI45732.1 - 1.7e-19 69.7 0.0 2.4e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Plasmid_RAQPRD PF09686.5 KPI45732.1 - 0.014 15.4 0.2 0.045 13.8 0.1 1.8 1 1 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Methyltransf_23 PF13489.1 KPI45733.1 - 1.2e-13 51.1 0.0 2.2e-13 50.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI45733.1 - 4.3e-08 33.5 0.0 9.9e-08 32.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI45733.1 - 7.7e-07 29.6 0.0 1.4e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI45733.1 - 3.9e-06 26.5 0.0 8e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI45733.1 - 6e-05 23.4 0.0 0.00015 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI45733.1 - 8.7e-05 22.8 0.0 0.00018 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KPI45733.1 - 0.004 16.2 0.0 0.0097 14.9 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase CheR PF01739.13 KPI45733.1 - 0.004 16.4 0.0 0.0077 15.5 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 KPI45733.1 - 0.009 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KPI45733.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain SUI1 PF01253.17 KPI45734.1 - 2.6e-22 78.4 4.7 3.9e-22 77.8 3.3 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2717 PF10911.3 KPI45734.1 - 0.043 13.3 0.1 0.093 12.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2717) Ocnus PF05005.10 KPI45734.1 - 0.05 13.4 0.2 0.071 12.9 0.1 1.2 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) DUF77 PF01910.12 KPI45734.1 - 0.061 12.9 0.1 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF77 RPEL PF02755.10 KPI45734.1 - 0.47 9.8 2.8 5.4 6.4 0.1 3.1 3 0 0 3 3 3 0 RPEL repeat WD40 PF00400.27 KPI45736.1 - 3.4e-68 223.2 26.7 2e-09 36.9 0.3 12.2 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.6 KPI45736.1 - 1.5e-41 141.3 0.2 3e-41 140.3 0.1 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 KPI45736.1 - 1.5e-08 33.2 10.9 0.025 12.7 0.2 5.8 2 2 3 5 5 5 5 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KPI45736.1 - 0.012 13.9 0.0 0.65 8.2 0.0 2.6 2 1 0 2 2 2 0 Cytochrome D1 heme domain Utp12 PF04003.7 KPI45736.1 - 0.053 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Dip2/Utp12 Family Herpes_gE PF02480.11 KPI45737.1 - 0.022 13.0 0.0 0.031 12.5 0.0 1.3 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E HemY_N PF07219.8 KPI45737.1 - 0.033 13.7 0.4 0.051 13.1 0.3 1.2 1 0 0 1 1 1 0 HemY protein N-terminus YajC PF02699.10 KPI45737.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit CcoS PF03597.10 KPI45737.1 - 0.17 11.3 0.8 0.24 10.8 0.5 1.2 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Ras PF00071.17 KPI45738.1 - 1.2e-59 200.3 0.5 1.3e-59 200.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KPI45738.1 - 6.3e-20 71.8 0.1 1.2e-19 70.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KPI45738.1 - 2.2e-15 56.3 0.0 2.8e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KPI45738.1 - 4.5e-09 36.0 0.1 8.1e-09 35.1 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KPI45738.1 - 1.1e-07 31.2 0.1 1.3e-07 31.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KPI45738.1 - 9.1e-06 25.6 0.0 1.3e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KPI45738.1 - 0.0043 17.1 0.1 0.91 9.6 0.0 2.5 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 KPI45738.1 - 0.038 13.1 0.3 0.16 11.1 0.0 2.0 2 1 0 3 3 3 0 Protein of unknown function, DUF258 Shikimate_DH PF01488.15 KPI45738.1 - 0.049 13.7 0.0 0.2 11.7 0.0 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase AAA_16 PF13191.1 KPI45738.1 - 0.054 13.4 0.2 0.16 11.8 0.1 1.9 1 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 KPI45738.1 - 0.15 11.9 0.1 0.26 11.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain adh_short_C2 PF13561.1 KPI45739.1 - 9.8e-20 71.3 0.0 8.3e-09 35.5 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KPI45739.1 - 5.8e-19 68.6 2.3 7.3e-18 65.0 1.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KPI45739.1 - 2.8e-08 33.6 1.4 1e-06 28.5 0.1 2.1 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KPI45739.1 - 0.028 14.4 0.5 0.62 10.0 0.3 2.6 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 KPI45739.1 - 0.12 11.7 0.1 3.2 7.1 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Sod_Fe_C PF02777.13 KPI45740.1 - 2.6e-15 56.1 0.3 1.5e-07 31.2 0.2 2.6 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KPI45740.1 - 0.14 12.4 2.9 0.33 11.2 2.0 1.6 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain HEAT PF02985.17 KPI45742.1 - 1.6e-10 40.1 3.5 0.074 13.1 0.0 6.0 5 0 0 5 5 5 4 HEAT repeat Pkinase PF00069.20 KPI45742.1 - 1.9e-08 33.7 0.0 3e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HEAT_2 PF13646.1 KPI45742.1 - 4.9e-06 26.7 0.2 0.0018 18.5 0.1 3.4 1 1 2 3 3 3 2 HEAT repeats Pkinase_Tyr PF07714.12 KPI45742.1 - 5.5e-06 25.6 0.0 1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 KPI45742.1 - 3.3e-05 24.2 0.1 0.53 10.8 0.0 3.2 2 1 0 2 2 2 2 HEAT-like repeat CLASP_N PF12348.3 KPI45742.1 - 0.0022 17.4 0.1 0.078 12.3 0.0 2.6 1 1 2 3 3 3 1 CLASP N terminal Kinase-like PF14531.1 KPI45742.1 - 0.02 13.8 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Adaptin_N PF01602.15 KPI45742.1 - 0.17 10.1 0.1 1.2 7.3 0.1 1.9 1 1 1 2 2 2 0 Adaptin N terminal region GSDH PF07995.6 KPI45744.1 - 5.7e-07 28.9 3.1 1.3e-06 27.7 2.2 1.7 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 KPI45744.1 - 0.0003 20.6 0.0 0.02 14.8 0.0 3.5 3 0 0 3 3 3 1 NHL repeat Tachylectin PF14517.1 KPI45744.1 - 0.0042 16.4 0.6 0.25 10.6 0.0 2.8 3 0 0 3 3 3 1 Tachylectin SBBP PF06739.6 KPI45744.1 - 0.043 13.6 0.1 4.3 7.2 0.0 3.4 4 0 0 4 4 4 0 Beta-propeller repeat Tudor-knot PF11717.3 KPI45745.1 - 0.15 11.8 1.2 0.31 10.7 0.8 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Glycos_transf_1 PF00534.15 KPI45746.1 - 8.1e-22 77.4 0.0 1.5e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KPI45746.1 - 2.2e-11 43.7 1.5 7.4e-11 42.0 1.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KPI45746.1 - 3.7e-11 43.3 0.7 1.6e-10 41.2 0.1 2.1 2 1 1 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KPI45746.1 - 5.5e-08 32.9 0.1 1.7e-07 31.3 0.0 1.9 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KPI45746.1 - 4.9e-06 26.7 1.7 4.9e-06 26.7 1.2 2.3 2 2 1 3 3 3 1 Glycosyl transferase 4-like domain Aminotran_4 PF01063.14 KPI45747.1 - 1.9e-18 66.7 0.0 1.3e-17 64.1 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class IV p450 PF00067.17 KPI45748.1 - 9.9e-69 232.0 0.0 1.2e-68 231.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kelch_3 PF13415.1 KPI45749.1 - 2.8e-31 106.9 13.7 2.5e-09 37.0 0.0 8.0 9 0 0 9 9 9 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KPI45749.1 - 1.2e-26 92.2 13.8 3.6e-07 29.8 0.0 7.1 6 2 0 6 6 6 4 Galactose oxidase, central domain DUF4110 PF13422.1 KPI45749.1 - 1.8e-25 88.5 2.7 1.8e-25 88.5 1.9 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 KPI45749.1 - 1.1e-24 85.4 4.5 1.2e-05 25.2 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 KPI45749.1 - 3.6e-23 81.0 1.6 7e-06 25.8 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 KPI45749.1 - 5.8e-18 63.8 8.4 9.5e-07 28.3 0.1 6.1 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 KPI45749.1 - 3.1e-15 55.4 3.0 2.5e-09 36.5 0.2 5.3 4 1 0 4 4 4 3 Kelch motif Ribosomal_S18 PF01084.15 KPI45750.1 - 6e-16 58.0 1.2 1.2e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S18 DUF3248 PF11609.3 KPI45751.1 - 0.088 12.5 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) FAD_binding_3 PF01494.14 KPI45752.1 - 4.7e-25 88.3 1.0 2.5e-24 86.0 0.7 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI45752.1 - 2e-08 33.5 0.4 0.002 17.1 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 KPI45752.1 - 4.5e-05 22.4 0.0 0.0015 17.4 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.7 KPI45752.1 - 0.00013 20.9 0.9 0.055 12.3 0.3 2.8 2 1 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 KPI45752.1 - 0.0019 18.1 0.0 0.0062 16.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KPI45752.1 - 0.0032 17.8 0.1 1.1 9.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI45752.1 - 0.013 14.3 0.7 1.2 7.9 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain Pyr_redox_2 PF07992.9 KPI45752.1 - 0.032 14.1 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lipase_3 PF01764.20 KPI45753.1 - 1.3e-20 73.4 0.0 1e-18 67.3 0.0 2.3 1 1 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 KPI45753.1 - 0.0011 19.2 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 KPI45753.1 - 0.002 17.8 0.0 0.0059 16.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI45753.1 - 0.0027 17.2 0.0 0.0056 16.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KPI45753.1 - 0.003 17.4 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KPI45753.1 - 0.0049 16.2 0.0 0.055 12.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Esterase PF00756.15 KPI45753.1 - 0.005 16.2 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 KPI45753.1 - 0.034 13.7 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Cutinase PF01083.17 KPI45753.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase 3Beta_HSD PF01073.14 KPI45754.1 - 4.6e-51 173.1 0.0 5.6e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KPI45754.1 - 3.1e-29 102.0 0.2 3.8e-29 101.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KPI45754.1 - 4.3e-14 52.0 0.2 1e-10 41.0 0.1 2.2 1 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 KPI45754.1 - 1.5e-13 50.3 0.0 2.1e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KPI45754.1 - 1.5e-07 31.5 0.0 2.3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KPI45754.1 - 5.1e-06 26.4 0.1 1.2e-05 25.2 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KPI45754.1 - 0.0015 17.5 0.3 0.0051 15.7 0.2 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KPI45754.1 - 0.0018 17.9 0.2 0.0064 16.1 0.2 1.9 1 1 0 1 1 1 1 KR domain ABC_membrane PF00664.18 KPI45755.1 - 1.1e-62 211.9 28.0 2.6e-35 122.1 7.7 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 KPI45755.1 - 1.3e-60 203.6 0.0 2.7e-29 102.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KPI45755.1 - 8e-16 57.9 0.5 8.3e-07 28.4 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KPI45755.1 - 6.5e-09 36.6 0.2 0.012 16.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_21 PF13304.1 KPI45755.1 - 7.6e-09 35.9 0.2 0.016 15.1 0.1 3.8 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KPI45755.1 - 7.7e-09 34.9 2.9 0.001 18.5 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KPI45755.1 - 1.3e-08 35.0 0.4 0.0015 18.5 0.0 3.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KPI45755.1 - 3.3e-08 33.7 0.8 0.0051 16.9 0.0 4.0 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 KPI45755.1 - 6.1e-07 28.7 0.0 0.02 14.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KPI45755.1 - 1.4e-06 27.8 0.0 0.0049 16.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 KPI45755.1 - 1.8e-06 28.2 0.1 0.04 14.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KPI45755.1 - 3.6e-06 25.8 0.3 1.1 7.8 0.0 4.1 4 0 0 4 4 4 3 Predicted ATPase of the ABC class AAA_10 PF12846.2 KPI45755.1 - 9e-06 25.3 6.2 0.036 13.5 0.1 3.5 3 0 0 3 3 3 2 AAA-like domain AAA_33 PF13671.1 KPI45755.1 - 1.9e-05 24.5 0.0 0.11 12.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KPI45755.1 - 2.4e-05 24.7 7.0 0.031 14.6 0.1 2.6 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.16 KPI45755.1 - 0.00056 19.1 0.0 0.099 11.7 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MobB PF03205.9 KPI45755.1 - 0.00064 19.4 0.6 0.19 11.3 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.1 KPI45755.1 - 0.00083 17.9 0.4 0.055 11.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KPI45755.1 - 0.00084 19.0 0.9 1.4 8.6 0.0 4.3 5 0 0 5 5 5 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 KPI45755.1 - 0.0009 19.1 0.5 0.72 9.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 KPI45755.1 - 0.0017 18.2 0.0 1.5 8.7 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF3987 PF13148.1 KPI45755.1 - 0.002 16.7 0.0 0.87 8.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) T2SE PF00437.15 KPI45755.1 - 0.0046 15.9 0.2 0.5 9.2 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 KPI45755.1 - 0.0061 16.1 0.0 7.2 6.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KPI45755.1 - 0.0096 16.0 0.1 7.4 6.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 KPI45755.1 - 0.01 15.3 0.0 6.2 6.2 0.0 2.8 3 0 0 3 3 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KPI45755.1 - 0.011 14.8 0.5 2 7.4 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin NB-ARC PF00931.17 KPI45755.1 - 0.011 14.5 0.0 1.2 7.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.12 KPI45755.1 - 0.011 15.5 5.3 0.59 9.8 0.3 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF87 NACHT PF05729.7 KPI45755.1 - 0.013 15.2 0.0 2.7 7.6 0.0 2.7 2 0 0 2 2 2 0 NACHT domain APS_kinase PF01583.15 KPI45755.1 - 0.015 14.9 0.3 2 8.0 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_14 PF13173.1 KPI45755.1 - 0.029 14.2 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KPI45755.1 - 0.052 12.6 0.8 3.2 6.8 0.0 2.5 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.21 KPI45755.1 - 0.06 12.8 0.0 4 6.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Guanylate_kin PF00625.16 KPI45755.1 - 0.073 12.5 0.1 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase AAA_15 PF13175.1 KPI45755.1 - 0.079 11.9 0.0 17 4.2 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain ATP_bind_1 PF03029.12 KPI45755.1 - 0.11 12.0 0.4 3.5 7.1 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PhoH PF02562.11 KPI45755.1 - 0.11 11.7 0.5 11 5.2 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein Gtr1_RagA PF04670.7 KPI45755.1 - 0.12 11.4 0.1 6 5.9 0.0 2.9 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region Miro PF08477.8 KPI45755.1 - 0.19 12.2 0.0 14 6.2 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 KPI45755.1 - 0.2 11.1 0.6 3.3 7.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain CbiA PF01656.18 KPI45755.1 - 0.23 10.8 0.9 5.4 6.3 0.1 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Arch_ATPase PF01637.13 KPI45755.1 - 0.31 10.7 0.0 29 4.2 0.0 2.6 3 0 0 3 3 2 0 Archaeal ATPase RNA12 PF10443.4 KPI45755.1 - 0.39 9.1 0.0 20 3.5 0.0 2.2 2 0 0 2 2 2 0 RNA12 protein TPR_MLP1_2 PF07926.7 KPI45756.1 - 9.4e-05 22.1 15.4 0.00012 21.8 2.8 2.4 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.4 KPI45756.1 - 0.0036 17.3 12.2 0.0066 16.4 8.4 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Usp PF00582.21 KPI45756.1 - 0.047 13.8 0.1 0.18 11.9 0.1 2.0 1 0 0 1 1 1 0 Universal stress protein family DUF3450 PF11932.3 KPI45756.1 - 0.12 11.5 13.0 0.11 11.7 8.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) APG6 PF04111.7 KPI45756.1 - 0.15 11.0 12.9 0.24 10.3 8.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 KPI45756.1 - 0.28 10.3 15.1 0.73 8.9 10.5 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4140 PF13600.1 KPI45756.1 - 1.1 9.7 7.5 21 5.6 0.1 2.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 KPI45756.1 - 1.2 8.6 20.3 29 4.1 14.1 2.2 1 1 0 1 1 1 0 IncA protein DUF342 PF03961.8 KPI45756.1 - 3.5 5.9 5.7 5.1 5.4 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Atg14 PF10186.4 KPI45756.1 - 3.7 6.4 17.8 9 5.1 12.3 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_S64 PF08192.6 KPI45756.1 - 3.8 5.7 9.6 5.2 5.2 6.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Peptidase_M48 PF01435.13 KPI45757.1 - 6.4e-54 182.8 0.0 9.3e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 KPI45757.1 - 0.0008 18.4 0.6 0.0044 16.0 0.1 2.1 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF2201_N PF13203.1 KPI45757.1 - 0.03 13.4 0.6 0.14 11.3 0.4 1.9 2 0 0 2 2 2 0 Putative metallopeptidase domain Acetyltransf_7 PF13508.1 KPI45758.1 - 0.0013 18.8 0.0 0.0034 17.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KPI45758.1 - 0.0066 16.4 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KPI45758.1 - 0.015 15.1 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NAD_binding_10 PF13460.1 KPI45759.1 - 6.2e-05 23.0 0.0 0.00069 19.6 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KPI45759.1 - 0.0012 17.8 0.9 0.0078 15.1 0.0 2.4 3 1 0 3 3 3 1 Male sterility protein 3Beta_HSD PF01073.14 KPI45759.1 - 0.005 15.5 0.0 1 7.9 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KPI45759.1 - 0.042 13.2 0.0 0.077 12.4 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3074 PF11274.3 KPI45760.1 - 1.2e-30 106.5 0.0 2.5e-30 105.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) Zn_clus PF00172.13 KPI45762.1 - 1e-07 31.7 12.8 2.2e-07 30.6 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mac PF12464.3 KPI45762.1 - 1.7e-07 31.1 2.2 1.7e-07 31.1 1.5 1.9 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep PF00132.19 KPI45762.1 - 3e-07 29.6 9.7 0.0012 18.2 2.9 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KPI45762.1 - 0.00075 19.0 9.5 0.024 14.1 3.2 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase MFS_1 PF07690.11 KPI45763.1 - 2.5e-28 98.7 46.4 2.5e-28 98.7 32.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_11 PF01531.11 KPI45764.1 - 0.12 11.3 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 11 Histidinol_dh PF00815.15 KPI45765.1 - 0.21 10.1 0.7 0.26 9.8 0.5 1.1 1 0 0 1 1 1 0 Histidinol dehydrogenase SYF2 PF08231.7 KPI45766.1 - 2.5e-38 131.5 6.5 5.1e-38 130.5 4.5 1.5 1 0 0 1 1 1 1 SYF2 splicing factor Far-17a_AIG1 PF04750.9 KPI45767.1 - 3.6e-65 218.9 8.8 4.2e-65 218.6 6.1 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF3176 PF11374.3 KPI45768.1 - 5.7e-33 113.1 1.5 1.3e-32 111.9 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Aldose_epim PF01263.15 KPI45770.1 - 5.7e-40 137.2 0.0 6.4e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase PPTA PF01239.17 KPI45772.1 - 2.9e-39 130.7 23.8 4.4e-08 32.1 0.1 6.2 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.1 KPI45772.1 - 3.6 7.1 12.8 30 4.1 0.2 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4219) Abhydrolase_6 PF12697.2 KPI45773.1 - 1e-28 100.7 0.0 1.2e-28 100.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KPI45773.1 - 4.9e-14 52.3 0.0 7.7e-14 51.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KPI45773.1 - 1.4e-12 47.6 0.0 2.8e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KPI45773.1 - 6.7e-09 35.4 0.1 1.5e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KPI45773.1 - 0.0037 16.4 0.0 0.91 8.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KPI45773.1 - 0.013 15.0 0.0 0.98 8.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.15 KPI45773.1 - 0.026 14.7 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 KPI45773.1 - 0.058 12.8 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase BAAT_C PF08840.6 KPI45773.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Glyoxalase_2 PF12681.2 KPI45774.1 - 3.6e-08 33.9 0.0 7.3e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KPI45774.1 - 3.1e-06 27.1 0.3 6e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.13 KPI45774.1 - 0.0013 17.7 0.0 0.0024 16.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cullin PF00888.17 KPI45775.1 - 1.1e-118 397.3 8.8 1.1e-118 397.3 6.1 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 KPI45775.1 - 1.5e-29 101.6 4.2 1.6e-29 101.5 1.4 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain MAP65_ASE1 PF03999.7 KPI45776.1 - 6.7 5.1 5.8 8.3 4.8 4.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Rif1_N PF12231.3 KPI45777.1 - 8e-50 169.8 0.1 1.3e-49 169.1 0.1 1.4 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal SNF2_N PF00176.18 KPI45778.1 - 8.8e-62 208.5 0.4 1.7e-61 207.6 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KPI45778.1 - 7.2e-13 48.2 0.0 2e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KPI45778.1 - 3.6e-06 26.9 0.0 9.2e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 KPI45778.1 - 5.2e-05 22.8 10.7 5.2e-05 22.8 7.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KPI45778.1 - 0.00043 20.0 10.2 0.00043 20.0 7.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KPI45778.1 - 0.0012 18.8 10.0 0.0012 18.8 6.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.1 KPI45778.1 - 0.0014 17.5 0.2 0.0058 15.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 DUF1949 PF09186.6 KPI45778.1 - 0.18 11.3 0.3 0.56 9.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) Zn_Tnp_IS91 PF14319.1 KPI45778.1 - 1.4 8.4 16.1 0.32 10.5 2.3 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_5 PF14634.1 KPI45778.1 - 8.6 6.1 25.9 0.099 12.3 7.6 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-C2H2_4 PF13894.1 KPI45779.1 - 0.00036 20.6 7.5 1.4 9.4 0.1 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KPI45779.1 - 0.044 14.1 1.0 0.044 14.1 0.7 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type KH_1 PF00013.24 KPI45781.1 - 6.3e-05 22.5 0.9 0.00012 21.6 0.6 1.4 1 0 0 1 1 1 1 KH domain FMO-like PF00743.14 KPI45783.1 - 2.6e-23 82.0 0.0 2.4e-07 29.3 0.1 3.3 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KPI45783.1 - 3.2e-13 50.2 0.0 2.2e-06 27.9 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KPI45783.1 - 1.9e-11 43.9 0.3 1.6e-05 24.7 0.0 3.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 KPI45783.1 - 1e-08 34.5 0.1 3.4e-07 29.5 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KPI45783.1 - 1.6e-08 34.7 0.0 0.0047 16.8 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI45783.1 - 2.9e-08 33.6 0.0 8.5e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KPI45783.1 - 4.3e-08 32.6 0.1 0.0066 15.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 KPI45783.1 - 4.4e-05 22.7 3.5 5.7e-05 22.3 0.3 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 KPI45783.1 - 5.3e-05 22.2 0.5 0.17 10.7 0.1 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KPI45783.1 - 6.2e-05 22.1 0.2 0.00013 21.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KPI45783.1 - 0.00067 18.2 0.5 0.0021 16.6 0.4 1.7 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KPI45783.1 - 0.00086 18.2 0.1 0.0024 16.7 0.2 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KPI45783.1 - 0.0031 17.9 1.1 0.0062 16.9 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KPI45783.1 - 0.0054 15.6 0.3 0.017 13.9 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 KPI45783.1 - 0.009 15.6 0.3 0.019 14.6 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KPI45783.1 - 0.022 13.7 0.6 0.044 12.8 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain REV PF00424.13 KPI45783.1 - 0.059 13.2 0.5 0.14 12.0 0.3 1.6 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) ApbA PF02558.11 KPI45783.1 - 0.27 10.6 0.9 0.54 9.6 0.6 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Methyltransf_12 PF08242.7 KPI45785.1 - 2e-13 50.6 0.0 4.7e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KPI45785.1 - 2.2e-13 50.4 0.0 4.4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI45785.1 - 6.2e-12 45.5 0.0 1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI45785.1 - 1.5e-11 44.5 0.0 4.5e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI45785.1 - 1.4e-09 37.7 0.0 2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KPI45785.1 - 2.2e-08 34.6 0.0 4.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KPI45785.1 - 6e-07 28.8 0.0 9.1e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KPI45785.1 - 2.9e-06 27.2 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KPI45785.1 - 6.2e-05 22.0 0.0 0.021 13.7 0.0 2.1 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family MTS PF05175.9 KPI45785.1 - 0.00038 19.8 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KPI45785.1 - 0.0015 17.6 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DUF3419 PF11899.3 KPI45785.1 - 0.0029 16.3 0.0 0.0042 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) TehB PF03848.9 KPI45785.1 - 0.0096 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_8 PF05148.10 KPI45785.1 - 0.016 14.8 0.0 0.12 11.9 0.0 2.2 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_24 PF13578.1 KPI45785.1 - 0.028 15.2 0.0 0.077 13.8 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain TPMT PF05724.6 KPI45785.1 - 0.029 13.7 0.1 0.069 12.5 0.1 1.7 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_28 PF02636.12 KPI45785.1 - 0.033 13.5 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.4 KPI45785.1 - 0.056 12.8 0.0 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DUF1640 PF07798.6 KPI45787.1 - 3.6e-49 167.1 10.8 4.8e-49 166.7 7.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Metal_resist PF13801.1 KPI45787.1 - 4.5 7.2 12.4 0.48 10.4 1.5 2.8 2 1 1 3 3 3 0 Heavy-metal resistance A_deaminase PF00962.17 KPI45788.1 - 2.2e-39 135.2 0.0 2.9e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Tower PF09121.5 KPI45788.1 - 0.12 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Tower DnaJ PF00226.26 KPI45789.1 - 3.1e-11 42.8 1.9 1e-10 41.1 1.3 1.9 1 1 0 1 1 1 1 DnaJ domain PP28 PF10252.4 KPI45789.1 - 0.26 11.3 8.8 3.8 7.5 0.1 2.6 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 DDHD PF02862.12 KPI45789.1 - 1.5 8.5 5.3 3.1 7.5 0.2 2.1 2 0 0 2 2 2 0 DDHD domain TFIIF_alpha PF05793.7 KPI45790.1 - 1.7 6.9 9.6 2.4 6.4 6.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.7 KPI45790.1 - 5.4 6.1 11.4 50 3.0 7.9 2.2 1 1 0 1 1 1 0 SDA1 MFS_1 PF07690.11 KPI45792.1 - 2.2e-27 95.7 24.7 6e-26 90.9 6.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SLX9 PF15341.1 KPI45793.1 - 6.9e-32 110.4 0.8 1e-31 109.9 0.6 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 HrpJ PF07201.6 KPI45793.1 - 0.015 15.3 0.9 0.098 12.6 0.2 2.0 2 0 0 2 2 2 0 HrpJ-like domain MFS_1 PF07690.11 KPI45795.1 - 4.7e-32 111.0 12.5 6.4e-32 110.6 8.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HIG_1_N PF04588.8 KPI45796.1 - 9.6e-23 79.6 0.7 2.5e-22 78.3 0.1 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region PocR PF10114.4 KPI45796.1 - 0.019 14.0 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR Pedibin PF08182.6 KPI45796.1 - 0.25 10.8 2.7 0.41 10.1 1.9 1.3 1 0 0 1 1 1 0 Pedibin/Hym-346 family eIF2_C PF09173.6 KPI45797.1 - 1.7e-36 124.1 0.3 2.8e-36 123.4 0.2 1.4 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KPI45797.1 - 2e-13 50.2 0.7 3.8e-13 49.3 0.5 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 UPF0075 PF03702.9 KPI45798.1 - 2e-79 267.1 0.0 2.4e-79 266.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) DUF427 PF04248.7 KPI45798.1 - 0.014 15.0 0.0 0.072 12.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF427) GCD14_N PF14801.1 KPI45799.1 - 0.16 11.5 0.2 0.32 10.5 0.1 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term zf-C2H2 PF00096.21 KPI45800.1 - 1.7e-14 53.1 17.1 0.0014 18.8 0.0 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI45800.1 - 6.3e-13 48.0 14.6 0.0093 16.2 1.7 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KPI45800.1 - 1.3e-11 44.2 7.4 0.0051 16.9 0.0 5.0 4 1 1 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KPI45800.1 - 5.3e-06 26.1 9.4 0.048 13.5 0.3 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 KPI45800.1 - 5.4e-06 26.4 11.0 0.44 10.8 0.0 4.9 5 0 0 5 5 4 3 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 KPI45800.1 - 1.8e-05 24.7 16.6 0.023 15.0 0.3 4.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.7 KPI45800.1 - 0.00011 22.2 5.1 4.4 7.4 0.0 4.3 4 0 0 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KPI45800.1 - 0.001 19.1 9.1 0.75 9.9 0.1 4.2 3 1 1 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 KPI45800.1 - 0.0019 17.7 16.8 0.034 13.8 0.2 4.0 4 0 0 4 4 4 2 zinc-finger of a C2HC-type zf-DNA_Pol PF08996.5 KPI45800.1 - 0.0048 16.2 3.6 0.32 10.3 0.1 2.2 2 0 0 2 2 2 2 DNA Polymerase alpha zinc finger Sgf11 PF08209.6 KPI45800.1 - 0.0075 15.5 5.2 3.9 6.8 0.1 3.6 3 0 0 3 3 3 1 Sgf11 (transcriptional regulation protein) zf-FPG_IleRS PF06827.9 KPI45800.1 - 0.027 14.1 10.7 0.27 10.9 0.1 3.9 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS zf-AD PF07776.10 KPI45800.1 - 0.042 13.8 0.0 12 5.9 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) ADK_lid PF05191.9 KPI45800.1 - 0.083 12.5 8.4 5.9 6.6 0.0 4.0 4 0 0 4 4 4 0 Adenylate kinase, active site lid Trm112p PF03966.11 KPI45800.1 - 0.13 12.6 8.3 1 9.7 0.4 3.5 2 2 0 2 2 2 0 Trm112p-like protein TFIIS_C PF01096.13 KPI45800.1 - 0.15 11.6 6.9 29 4.4 0.1 4.3 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 KPI45800.1 - 0.17 11.7 20.0 2.4 8.0 0.3 4.2 2 2 2 4 4 4 0 Transposase zinc-ribbon domain FYDLN_acid PF09538.5 KPI45800.1 - 0.17 12.4 13.2 1 9.9 0.2 4.3 3 1 0 3 3 3 0 Protein of unknown function (FYDLN_acid) HypA PF01155.14 KPI45800.1 - 0.58 9.8 5.8 5.3 6.7 0.3 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family FYVE PF01363.16 KPI45800.1 - 1.1 9.1 14.5 0.2 11.5 1.1 2.6 2 1 0 2 2 2 0 FYVE zinc finger zf-ribbon_3 PF13248.1 KPI45800.1 - 1.3 8.2 12.1 4.5 6.6 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.2 KPI45800.1 - 1.5 8.7 15.7 6.3 6.6 2.4 3.0 2 2 0 2 2 2 0 Double zinc ribbon zinc_ribbon_5 PF13719.1 KPI45800.1 - 2.3 7.8 14.3 25 4.5 0.1 4.3 4 0 0 4 4 4 0 zinc-ribbon domain zf-ISL3 PF14690.1 KPI45800.1 - 2.3 8.3 13.0 30 4.7 0.0 4.3 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_4 PF13717.1 KPI45800.1 - 3.1 7.5 14.3 27 4.5 0.3 4.3 4 0 0 4 4 4 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 KPI45800.1 - 5 6.8 14.1 3.1 7.5 2.0 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-AN1 PF01428.11 KPI45800.1 - 7.3 6.5 15.4 19 5.2 0.2 4.3 3 1 1 4 4 4 0 AN1-like Zinc finger Terminase_GpA PF05876.7 KPI45800.1 - 8.3 4.6 10.2 0.088 11.1 0.4 2.0 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) UPF0547 PF10571.4 KPI45800.1 - 8.9 6.1 15.4 18 5.0 0.6 4.4 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 HET PF06985.6 KPI45802.1 - 1.7e-21 76.8 4.3 2.4e-21 76.3 3.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1136 PF06582.7 KPI45803.1 - 0.068 12.8 3.0 0.61 9.8 0.2 2.9 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) Laminin_II PF06009.7 KPI45803.1 - 0.33 10.6 26.2 0.33 10.7 4.4 4.5 3 1 0 4 4 4 0 Laminin Domain II Cep57_CLD PF14073.1 KPI45803.1 - 0.8 9.5 37.6 0.33 10.7 12.3 3.7 2 1 1 3 3 3 0 Centrosome localisation domain of Cep57 AAA_13 PF13166.1 KPI45803.1 - 1.5 7.2 30.1 1 7.7 1.3 3.1 3 1 0 3 3 3 0 AAA domain Fib_alpha PF08702.5 KPI45803.1 - 2.1 8.4 26.1 0.31 11.1 2.0 4.9 3 1 1 5 5 5 0 Fibrinogen alpha/beta chain family Fez1 PF06818.10 KPI45803.1 - 4 7.3 44.7 0.7 9.8 0.3 4.5 3 1 1 4 4 4 0 Fez1 Filament PF00038.16 KPI45803.1 - 4.2 6.7 44.4 4.8 6.5 2.1 4.4 3 1 1 4 4 4 0 Intermediate filament protein DUF1664 PF07889.7 KPI45803.1 - 9.4 6.0 16.1 0.34 10.7 1.8 3.9 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Cation_efflux PF01545.16 KPI45804.1 - 1e-29 103.5 9.8 1.3e-29 103.2 6.8 1.1 1 0 0 1 1 1 1 Cation efflux family adh_short PF00106.20 KPI45805.1 - 2.4e-25 89.3 0.0 3.5e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KPI45805.1 - 6.9e-16 58.7 0.0 8.4e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI45805.1 - 1.8e-07 31.0 0.0 3.6e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KPI45805.1 - 0.0001 21.8 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KPI45805.1 - 0.00051 20.1 0.1 0.00077 19.5 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KPI45805.1 - 0.0016 17.3 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 KPI45805.1 - 0.017 14.3 0.1 0.037 13.2 0.1 1.6 2 0 0 2 2 2 0 NmrA-like family zf-RING_2 PF13639.1 KPI45806.1 - 1.5e-13 50.3 8.0 2.1e-13 49.8 5.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KPI45806.1 - 6.4e-09 35.8 3.6 1.1e-08 35.0 2.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 KPI45806.1 - 1.5e-06 28.0 5.4 2.8e-06 27.1 3.7 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 KPI45806.1 - 6.8e-06 25.8 6.0 2.2e-05 24.1 4.2 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KPI45806.1 - 9.9e-06 25.1 5.3 1.5e-05 24.5 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI45806.1 - 1e-05 25.4 5.3 1.6e-05 24.8 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI45806.1 - 0.00016 21.3 4.3 0.00027 20.6 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KPI45806.1 - 0.0011 18.6 1.4 0.0019 17.8 1.0 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KPI45806.1 - 0.0023 17.5 6.7 0.0042 16.7 4.7 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KPI45806.1 - 0.0039 16.7 7.3 0.0059 16.1 5.0 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KPI45806.1 - 0.031 14.1 4.5 0.045 13.6 0.7 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 KPI45806.1 - 0.14 12.2 7.6 0.22 11.5 5.3 1.3 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.3 KPI45806.1 - 0.15 11.6 1.9 0.29 10.6 1.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.1 KPI45806.1 - 0.43 10.3 6.1 0.21 11.3 1.9 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 KPI45806.1 - 0.95 9.2 7.7 1.6 8.4 5.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-Di19 PF05605.7 KPI45806.1 - 5.7 7.1 7.0 14 5.9 0.3 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding OrfB_Zn_ribbon PF07282.6 KPI45806.1 - 8.5 6.1 6.2 6.5 6.4 1.5 2.1 1 1 1 2 2 2 0 Putative transposase DNA-binding domain DUF904 PF06005.7 KPI45807.1 - 0.043 14.1 5.2 0.98 9.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) ADIP PF11559.3 KPI45807.1 - 2.7 7.8 9.7 11 5.8 0.7 2.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding PIG-U PF06728.8 KPI45808.1 - 1.8e-111 372.7 24.9 2e-111 372.5 17.3 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U MFS_1 PF07690.11 KPI45810.1 - 2.8e-06 26.2 22.1 8.7e-06 24.6 11.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KPI45810.1 - 0.91 7.8 11.2 2.1 6.6 7.7 1.7 1 1 1 2 2 2 0 MFS/sugar transport protein zf-H2C2_2 PF13465.1 KPI45812.1 - 2.5e-13 49.5 18.8 1.7e-06 27.9 1.5 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KPI45812.1 - 2.2e-10 40.2 23.2 0.0098 16.1 0.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KPI45812.1 - 3.8e-08 33.1 21.0 0.0055 16.9 4.0 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 KPI45812.1 - 0.0029 17.6 11.2 0.016 15.3 4.9 2.3 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 KPI45812.1 - 0.0068 16.0 0.8 0.0068 16.0 0.5 2.3 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-RING_3 PF14369.1 KPI45812.1 - 0.03 14.3 3.0 23 5.0 0.0 3.4 3 0 0 3 3 3 0 zinc-finger DZR PF12773.2 KPI45812.1 - 0.11 12.3 6.1 1.6 8.6 4.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_6 PF13912.1 KPI45812.1 - 0.13 12.2 14.1 0.51 10.3 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KPI45812.1 - 0.15 12.2 13.1 0.65 10.2 2.7 3.2 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 KPI45812.1 - 0.19 11.3 4.7 1.6 8.3 0.3 2.7 1 1 1 2 2 2 0 GAGA factor Zn_Tnp_IS1595 PF12760.2 KPI45812.1 - 0.21 11.4 7.9 1.4 8.8 2.5 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 KPI45812.1 - 0.26 11.2 8.4 3.1 7.8 1.8 3.1 1 1 2 3 3 3 0 Zinc ribbon domain zf-C3HC4_3 PF13920.1 KPI45812.1 - 0.32 10.7 4.4 3.1 7.5 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 KPI45812.1 - 0.32 10.4 1.6 9.4 5.7 0.2 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-CHY PF05495.7 KPI45812.1 - 0.54 10.4 7.7 1 9.5 5.4 1.4 1 0 0 1 1 1 0 CHY zinc finger zinc_ribbon_2 PF13240.1 KPI45812.1 - 0.58 9.7 3.9 5.3 6.6 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-CHCC PF10276.4 KPI45812.1 - 0.81 9.5 6.1 2.9 7.8 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger domain zinc-ribbons_6 PF07191.7 KPI45812.1 - 0.83 9.4 4.1 3.1 7.6 1.3 2.3 2 1 0 2 2 2 0 zinc-ribbons OrfB_Zn_ribbon PF07282.6 KPI45812.1 - 2.4 7.8 5.6 17 5.1 1.1 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain FYDLN_acid PF09538.5 KPI45812.1 - 3.2 8.3 4.8 31 5.2 1.5 3.0 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2H2_2 PF12756.2 KPI45812.1 - 4.1 7.5 11.6 3.3 7.8 1.3 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Peptidase_M28 PF04389.12 KPI45814.1 - 7.6e-32 110.4 0.0 1.2e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Na_Ca_ex PF01699.19 KPI45815.1 - 3.6e-49 165.9 39.7 9.7e-27 93.2 4.0 3.3 3 0 0 3 3 3 2 Sodium/calcium exchanger protein FA_desaturase PF00487.19 KPI45815.1 - 0.76 9.1 14.2 0.069 12.5 1.3 3.4 3 0 0 3 3 3 0 Fatty acid desaturase Fcf1 PF04900.7 KPI45816.1 - 6.9e-41 138.4 1.0 1.3e-40 137.5 0.1 1.7 2 0 0 2 2 2 1 Fcf1 Exostosin PF03016.10 KPI45816.1 - 0.04 12.9 0.0 0.054 12.5 0.0 1.1 1 0 0 1 1 1 0 Exostosin family WD40 PF00400.27 KPI45817.1 - 5.4e-39 130.7 6.7 5.9e-07 29.1 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 KPI45817.1 - 0.0027 17.2 0.0 0.009 15.4 0.0 2.0 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 KPI45817.1 - 0.055 11.5 0.0 0.23 9.5 0.0 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 2_5_RNA_ligase2 PF13563.1 KPI45819.1 - 8.8e-05 22.2 0.3 0.00012 21.8 0.2 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily MMR_HSR1 PF01926.18 KPI45820.1 - 7e-09 35.6 0.0 2.1e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KPI45820.1 - 0.0014 17.8 0.0 0.0036 16.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KPI45820.1 - 0.0051 15.9 0.0 0.0051 15.9 0.0 2.5 2 1 0 2 2 2 1 AIG1 family AAA_22 PF13401.1 KPI45820.1 - 0.0056 16.8 2.5 0.01 15.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 KPI45820.1 - 0.033 13.9 0.3 0.033 13.9 0.2 3.3 2 1 0 3 3 3 0 Domain of unknown function DUF87 VanW PF04294.8 KPI45820.1 - 0.085 12.0 0.1 0.21 10.8 0.1 1.6 1 0 0 1 1 1 0 VanW like protein FeoB_N PF02421.13 KPI45820.1 - 0.11 11.7 0.1 0.11 11.7 0.0 2.6 3 1 0 3 3 3 0 Ferrous iron transport protein B ABC_tran PF00005.22 KPI45820.1 - 0.44 10.8 0.0 0.44 10.8 0.0 3.2 2 1 0 2 2 1 0 ABC transporter Miro PF08477.8 KPI45820.1 - 0.46 10.9 3.3 0.54 10.7 0.0 2.8 3 1 0 3 3 3 0 Miro-like protein DUF2721 PF11026.3 KPI45820.1 - 0.47 10.0 0.0 0.47 10.0 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) DUF3584 PF12128.3 KPI45820.1 - 0.63 7.2 39.3 0.96 6.6 27.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_18 PF13238.1 KPI45820.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.3 2 1 2 4 4 3 0 AAA domain DUF572 PF04502.8 KPI45820.1 - 2 7.5 28.7 3.6 6.7 19.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) ATP_bind_1 PF03029.12 KPI45820.1 - 3.3 7.1 11.0 1.7 8.1 0.2 3.7 2 2 2 4 4 4 0 Conserved hypothetical ATP binding protein Fungal_trans PF04082.13 KPI45821.1 - 1.5e-30 105.9 0.0 2.5e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HSP20 PF00011.16 KPI45822.1 - 2.4e-16 59.4 1.5 6.1e-11 42.0 0.0 2.3 2 1 0 2 2 2 2 Hsp20/alpha crystallin family DUF4662 PF15578.1 KPI45822.1 - 0.24 10.9 3.8 0.34 10.4 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) RR_TM4-6 PF06459.7 KPI45822.1 - 0.42 10.4 7.4 0.54 10.0 5.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CMV_1a PF12467.3 KPI45822.1 - 0.61 10.4 9.5 0.63 10.3 6.2 1.3 1 1 0 1 1 1 0 Cucumber mosaic virus 1a protein family DDHD PF02862.12 KPI45822.1 - 1.1 9.0 4.8 1.3 8.7 3.3 1.2 1 0 0 1 1 1 0 DDHD domain ADH_zinc_N PF00107.21 KPI45823.1 - 1.5e-13 50.3 0.0 2e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KPI45823.1 - 0.025 15.4 0.0 0.039 14.8 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase SIS_2 PF13580.1 KPI45823.1 - 0.061 13.0 0.1 7.8 6.2 0.0 2.8 3 0 0 3 3 3 0 SIS domain ESX-1_EspG PF14011.1 KPI45823.1 - 0.097 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 EspG family PIG-S PF10510.4 KPI45824.1 - 1.1e-115 387.3 0.0 1.3e-115 387.0 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein 3H PF02829.9 KPI45824.1 - 0.091 12.7 0.1 0.99 9.4 0.0 2.3 2 0 0 2 2 2 0 3H domain LAMTOR PF15454.1 KPI45825.1 - 8.3e-06 25.9 0.1 3.1e-05 24.1 0.0 2.0 1 1 1 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Kinesin PF00225.18 KPI45827.1 - 1.4e-109 365.8 1.1 1.4e-109 365.8 0.8 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 KPI45827.1 - 2.3e-09 37.5 1.3 2.3e-09 37.5 0.9 6.4 3 2 3 6 6 6 1 Kinesin-associated microtubule-binding Apolipoprotein PF01442.13 KPI45827.1 - 0.0019 17.7 10.1 0.0019 17.7 7.0 4.2 1 1 3 4 4 4 2 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 KPI45827.1 - 0.35 10.6 0.0 0.35 10.6 0.0 6.2 3 1 5 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus CMD PF02627.15 KPI45828.1 - 1.6e-05 24.6 0.0 0.00031 20.5 0.0 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family His_Phos_1 PF00300.17 KPI45829.1 - 7.8e-14 52.0 0.0 2.2e-13 50.5 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ank_2 PF12796.2 KPI45830.1 - 0.0038 17.5 0.0 1.6 9.1 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KPI45830.1 - 0.045 14.2 0.0 4.6 7.8 0.0 3.2 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 KPI45830.1 - 0.1 12.8 0.1 28 5.1 0.0 4.3 4 1 1 5 5 5 0 Ankyrin repeats (many copies) FAD_binding_3 PF01494.14 KPI45831.1 - 8e-13 48.1 0.0 1.3e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI45831.1 - 7e-08 31.7 0.8 8e-05 21.6 0.3 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KPI45831.1 - 1.1e-06 28.5 0.2 2.3e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KPI45831.1 - 0.00049 20.0 1.0 0.0025 17.7 0.9 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KPI45831.1 - 0.0023 16.6 2.8 0.64 8.5 0.5 2.5 2 1 1 3 3 3 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 KPI45831.1 - 0.0024 17.9 0.2 0.018 15.1 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KPI45831.1 - 0.0044 15.9 1.1 0.01 14.6 0.8 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KPI45831.1 - 0.0081 15.7 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 KPI45831.1 - 0.012 14.4 0.1 0.032 13.0 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.13 KPI45831.1 - 0.014 15.0 0.3 0.024 14.3 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KPI45831.1 - 0.015 15.6 0.5 0.04 14.3 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI45831.1 - 0.017 13.6 0.8 0.03 12.8 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 KPI45831.1 - 0.019 14.7 1.8 0.14 11.9 0.7 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding Rossmann-like PF10727.4 KPI45831.1 - 0.032 13.9 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain VPEP PF07589.6 KPI45831.1 - 0.076 12.9 0.3 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 PEP-CTERM motif UDPG_MGDP_dh_N PF03721.9 KPI45831.1 - 0.096 12.0 0.2 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GD_AH_C PF04295.8 KPI45831.1 - 0.13 10.8 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus Lycopene_cycl PF05834.7 KPI45831.1 - 0.17 10.7 0.9 2.1 7.1 0.6 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein Ran-binding PF05508.6 KPI45833.1 - 2e-114 381.5 0.7 2.5e-114 381.2 0.5 1.1 1 0 0 1 1 1 1 RanGTP-binding protein Acetyltransf_2 PF00797.12 KPI45834.1 - 1.2e-38 133.0 0.0 1.5e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase Peptidase_C71 PF12386.3 KPI45834.1 - 0.0067 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Pseudomurein endo-isopeptidase Pei Transglut_core2 PF13369.1 KPI45834.1 - 0.018 14.5 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily Scytalone_dh PF02982.9 KPI45834.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Scytalone dehydratase Transposase_22 PF02994.9 KPI45835.1 - 0.039 12.4 0.1 0.046 12.2 0.1 1.1 1 0 0 1 1 1 0 L1 transposable element NOP5NT PF08156.8 KPI45835.1 - 0.087 12.9 0.3 6.7 6.9 0.0 2.5 1 1 0 2 2 2 0 NOP5NT (NUC127) domain DcpS PF05652.7 KPI45835.1 - 0.09 13.1 0.2 0.2 12.0 0.0 1.6 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal Syja_N PF02383.13 KPI45836.1 - 3.3e-90 302.0 0.0 4.1e-90 301.7 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Acetyltransf_3 PF13302.1 KPI45837.1 - 1.9e-25 89.6 0.0 2.6e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KPI45837.1 - 7.2e-09 35.6 0.0 6.2e-07 29.4 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KPI45837.1 - 4.8e-07 29.7 0.3 4.6e-06 26.5 0.2 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KPI45837.1 - 0.00047 19.8 0.1 0.03 14.0 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.1 KPI45837.1 - 0.071 13.0 0.1 0.9 9.4 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KPI45837.1 - 0.075 13.2 0.1 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease PF00324.16 KPI45838.1 - 3.7e-93 312.4 44.6 4.4e-93 312.2 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KPI45838.1 - 5e-22 78.0 46.2 6.9e-22 77.5 32.0 1.1 1 0 0 1 1 1 1 Amino acid permease YqzM PF14141.1 KPI45838.1 - 3 7.7 5.8 2.7 7.8 0.2 3.1 2 0 0 2 2 2 0 YqzM-like protein Herpes_LMP1 PF05297.6 KPI45838.1 - 4.4 6.1 6.5 10 4.9 4.5 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Proteasome PF00227.21 KPI45840.1 - 2.2e-33 115.1 0.0 2.5e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.20 KPI45842.1 - 1.9e-39 135.3 0.0 1.4e-38 132.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI45842.1 - 1.3e-27 96.5 0.0 1.9e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KPI45842.1 - 0.0065 16.2 0.8 0.021 14.5 0.1 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KPI45842.1 - 0.015 14.2 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KPI45842.1 - 0.22 10.5 0.0 0.46 9.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4279 PF14106.1 KPI45844.1 - 0.0028 17.5 0.0 0.0054 16.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4279) DUF1192 PF06698.6 KPI45844.1 - 0.077 12.8 0.1 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Ric8 PF10165.4 KPI45845.1 - 9.5e-89 298.2 0.0 1.1e-88 297.9 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn ATP-synt_S1 PF05827.7 KPI45846.1 - 1.8e-41 142.3 0.0 2.1e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) MCM2_N PF12619.3 KPI45847.1 - 0.87 9.5 5.8 1.9 8.4 0.3 2.6 3 0 0 3 3 3 0 Mini-chromosome maintenance protein 2 UPF0444 PF15475.1 KPI45848.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 Cytochrom_C1 PF02167.10 KPI45849.1 - 6e-81 271.2 0.0 7.2e-81 271.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KPI45849.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 KPI45849.1 - 0.049 14.4 2.3 0.17 12.7 0.2 2.7 3 1 0 3 3 3 0 Cytochrome c HCNGP PF07818.8 KPI45850.1 - 5.2e-25 87.3 0.0 7.8e-25 86.7 0.0 1.2 1 0 0 1 1 1 1 HCNGP-like protein Fungal_trans_2 PF11951.3 KPI45851.1 - 0.00012 20.8 0.0 0.00017 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRM_1 PF00076.17 KPI45852.1 - 7.4e-08 31.9 0.0 1.8e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KPI45852.1 - 2.5e-05 24.0 0.0 4.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KPI45852.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Methyltransf_PK PF05891.7 KPI45853.1 - 5.2e-63 212.2 0.0 4.1e-49 166.8 0.0 2.0 2 0 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 KPI45853.1 - 2.5e-05 24.8 0.0 4.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KPI45853.1 - 3.6e-05 23.5 0.0 6.4e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain DUF1754 PF08555.5 KPI45853.1 - 0.064 13.8 0.5 0.096 13.2 0.4 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Glyoxalase PF00903.20 KPI45854.1 - 0.0003 20.7 0.0 0.00051 20.0 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KPI45854.1 - 0.0034 17.9 0.0 0.18 12.4 0.0 2.2 1 1 1 2 2 2 1 Glyoxalase-like domain Glyoxalase_3 PF13468.1 KPI45854.1 - 0.028 14.3 0.1 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain Glyco_hydro_61 PF03443.9 KPI45856.1 - 2.8e-43 148.2 0.5 3.9e-43 147.8 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KPI45856.1 - 1.9e-14 53.0 12.8 4.3e-14 51.8 8.9 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Ribosomal_L14 PF00238.14 KPI45857.1 - 3.1e-33 114.1 1.6 3.4e-33 114.0 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PRY PF13765.1 KPI45857.1 - 0.098 12.2 0.0 0.16 11.5 0.0 1.4 1 1 0 1 1 1 0 SPRY-associated domain PemK PF02452.12 KPI45857.1 - 0.11 12.7 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 PemK-like protein Polysacc_synt_4 PF04669.8 KPI45858.1 - 8.5e-21 74.1 0.7 5.6e-20 71.5 0.5 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis p450 PF00067.17 KPI45859.1 - 1.7e-77 260.9 0.0 2.4e-77 260.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ilm1 PF10311.4 KPI45860.1 - 7e-21 74.4 0.2 6.1e-19 68.1 0.1 2.7 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 PQ-loop PF04193.9 KPI45861.1 - 5.1e-25 86.7 4.3 2.5e-15 55.7 0.4 2.5 2 0 0 2 2 2 2 PQ loop repeat BcsB PF03170.8 KPI45861.1 - 0.053 11.5 0.0 0.079 10.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit ATP13 PF12921.2 KPI45862.1 - 0.075 12.3 0.3 6.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ATPase expression MFS_1 PF07690.11 KPI45864.1 - 1.8e-30 105.8 36.6 1.8e-30 105.8 25.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI45864.1 - 1.8e-08 33.4 34.7 4e-08 32.2 24.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Folate_carrier PF01770.13 KPI45864.1 - 0.0028 16.2 0.5 0.0053 15.3 0.3 1.4 1 0 0 1 1 1 1 Reduced folate carrier DUF2611 PF11022.3 KPI45864.1 - 0.019 15.0 0.8 0.069 13.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) Amidase PF01425.16 KPI45865.1 - 2.4e-53 181.5 0.1 7.5e-53 179.9 0.1 1.7 1 1 0 1 1 1 1 Amidase DUF3506 PF12014.3 KPI45867.1 - 8.5e-42 142.1 0.0 3.5e-41 140.1 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) PHD PF00628.24 KPI45868.1 - 3e-17 62.0 16.5 6.8e-11 41.6 6.6 2.5 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.1 KPI45868.1 - 0.00052 19.3 5.8 0.013 14.7 1.3 2.6 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 KPI45868.1 - 0.004 16.4 3.6 0.004 16.4 2.5 2.8 3 0 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.1 KPI45868.1 - 0.0049 16.5 0.9 0.0049 16.5 0.6 2.9 3 0 0 3 3 3 2 Prokaryotic RING finger family 1 C1_1 PF00130.17 KPI45868.1 - 0.013 15.2 8.4 0.48 10.2 1.9 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 KPI45868.1 - 5 7.3 8.0 24 5.1 2.9 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain PAP2 PF01569.16 KPI45869.1 - 2.6e-18 65.9 4.5 2.6e-18 65.9 3.1 2.2 2 1 0 2 2 2 1 PAP2 superfamily MAT1 PF06391.8 KPI45870.1 - 2.7e-25 89.1 8.0 3.7e-25 88.7 5.6 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 KPI45870.1 - 2.2e-05 23.9 7.1 4.1e-05 23.1 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI45870.1 - 0.0017 18.3 8.6 0.003 17.5 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KPI45870.1 - 0.0018 18.0 7.6 0.0034 17.1 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KPI45870.1 - 0.0031 17.2 5.5 0.0061 16.2 3.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KPI45870.1 - 0.0043 16.7 9.2 0.013 15.2 2.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KPI45870.1 - 0.063 13.1 5.0 0.17 11.7 3.5 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KPI45870.1 - 0.24 10.9 5.6 0.57 9.7 3.9 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit HlyIII PF03006.15 KPI45871.1 - 6.7e-56 189.1 15.8 8.3e-56 188.8 10.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related Ribophorin_II PF05817.9 KPI45872.1 - 6.4e-17 61.0 0.0 8.1e-17 60.6 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II F-box-like PF12937.2 KPI45874.1 - 0.00046 19.8 1.1 0.0011 18.6 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KPI45874.1 - 0.046 13.3 0.3 0.1 12.2 0.2 1.6 1 0 0 1 1 1 0 F-box domain GHMP_kinases_N PF00288.21 KPI45875.1 - 8.4e-20 70.6 0.0 2.1e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KPI45875.1 - 1.5e-07 31.4 0.0 3.5e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 KPI45875.1 - 0.00019 20.6 0.2 0.00053 19.1 0.0 1.8 2 0 0 2 2 2 1 Galactokinase galactose-binding signature Glyco_tran_WecB PF03808.8 KPI45875.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family RRN9 PF10680.4 KPI45877.1 - 5e-15 54.9 0.7 1.4e-14 53.5 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor Pex14_N PF04695.8 KPI45877.1 - 0.29 11.1 0.0 0.29 11.1 0.0 3.8 4 1 1 5 5 5 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.17 KPI45878.1 - 8.6e-56 189.2 4.2 9.9e-56 189.0 2.9 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF872 PF05915.7 KPI45878.1 - 0.14 12.0 0.6 15 5.4 0.3 2.8 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) SAP PF02037.22 KPI45879.1 - 3.7e-13 48.6 0.2 7e-13 47.7 0.1 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 KPI45879.1 - 0.024 14.1 0.3 0.058 12.9 0.2 1.7 1 1 0 1 1 1 0 HeH/LEM domain PRCC PF10253.4 KPI45879.1 - 0.43 11.2 7.5 0.65 10.6 5.2 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting ADH_zinc_N PF00107.21 KPI45880.1 - 1.2e-06 28.0 0.0 2.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI45880.1 - 4.3e-06 26.4 0.0 1.8e-05 24.4 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain SGL PF08450.7 KPI45882.1 - 7.1e-50 169.6 0.3 9.9e-50 169.2 0.2 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KPI45882.1 - 0.0023 17.9 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.11 KPI45882.1 - 0.083 12.9 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Strictosidine synthase Amidase PF01425.16 KPI45883.1 - 4.5e-51 174.0 1.0 4.7e-48 164.1 0.7 3.0 1 1 0 1 1 1 1 Amidase Grp1_Fun34_YaaH PF01184.14 KPI45886.1 - 1.2e-84 282.8 19.9 1.5e-84 282.5 13.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Spherulin4 PF12138.3 KPI45888.1 - 2.8e-49 167.8 0.0 2.3e-47 161.5 0.0 2.0 1 1 0 1 1 1 1 Spherulation-specific family 4 ADH_zinc_N_2 PF13602.1 KPI45889.1 - 2.6e-13 50.9 0.0 5e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KPI45889.1 - 4.6e-08 32.6 0.4 6.2e-07 29.0 0.0 2.5 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI45889.1 - 0.0074 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 KPI45889.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PALP PF00291.20 KPI45890.1 - 4.5e-60 203.4 1.9 5.7e-60 203.1 1.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme hDGE_amylase PF14701.1 KPI45891.1 - 2e-172 573.8 0.0 2.8e-172 573.3 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KPI45891.1 - 3.8e-118 394.4 0.0 6.3e-118 393.7 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KPI45891.1 - 7.3e-84 281.0 0.0 1.2e-83 280.2 0.0 1.4 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 KPI45891.1 - 6.5e-29 99.6 0.0 1.3e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 KPI45891.1 - 0.0001 21.8 0.0 0.00066 19.1 0.0 2.0 2 0 0 2 2 2 1 Alpha amylase, catalytic domain 4HBT_3 PF13622.1 KPI45893.1 - 2.1e-43 148.8 0.0 2.6e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Cyclin PF08613.6 KPI45894.1 - 2.1e-32 112.5 5.0 1.2e-13 51.6 0.0 3.4 3 0 0 3 3 3 3 Cyclin DUF934 PF06073.7 KPI45895.1 - 0.055 13.1 0.3 0.081 12.6 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF934) adh_short PF00106.20 KPI45897.1 - 6.5e-20 71.7 1.5 9.1e-14 51.7 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KPI45897.1 - 1.3e-14 54.6 0.2 4e-11 43.1 0.0 2.9 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KPI45897.1 - 3.1e-06 26.9 1.6 0.0023 17.5 0.0 2.1 1 1 1 2 2 2 2 KR domain CorA PF01544.13 KPI45898.1 - 0.0021 17.1 2.4 0.0044 16.1 1.5 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein FAM110_C PF14160.1 KPI45898.1 - 1.9 9.4 5.2 1.1 10.2 0.1 2.8 3 0 0 3 3 3 0 Centrosome-associated C terminus Methyltransf_16 PF10294.4 KPI45899.1 - 4.1e-38 130.5 0.1 8.3e-38 129.5 0.1 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KPI45899.1 - 6.1e-06 26.7 0.0 1.2e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KPI45899.1 - 1e-05 24.9 0.0 1.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KPI45899.1 - 3.5e-05 23.5 0.0 5.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KPI45899.1 - 0.0002 21.8 0.1 0.0006 20.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI45899.1 - 0.00024 21.4 0.0 0.00045 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI45899.1 - 0.00028 20.8 0.0 0.00066 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KPI45899.1 - 0.0017 17.9 0.0 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 KPI45899.1 - 0.017 14.6 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Pkinase PF00069.20 KPI45900.1 - 6.2e-38 130.4 0.0 1.1e-37 129.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 KPI45900.1 - 1.2e-22 80.0 0.2 9.1e-16 57.8 0.1 3.3 2 1 0 2 2 2 2 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 KPI45900.1 - 2.2e-19 69.5 0.0 2.2e-18 66.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Nop53 PF07767.6 KPI45900.1 - 0.021 13.8 11.1 0.037 13.0 7.7 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Telomerase_RBD PF12009.3 KPI45901.1 - 2.3e-37 127.9 0.2 4.5e-37 126.9 0.2 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 KPI45901.1 - 0.012 14.9 0.0 0.035 13.4 0.0 1.7 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.11 KPI45902.1 - 2.5e-33 115.2 14.2 2.5e-33 115.2 9.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2668 PF10873.3 KPI45903.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) Acyl-CoA_dh_1 PF00441.19 KPI45904.1 - 4.9e-32 111.1 3.4 7.2e-32 110.5 0.7 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 KPI45904.1 - 3.9e-20 71.4 0.2 9.9e-20 70.1 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 KPI45904.1 - 2.4e-17 62.1 3.0 8.8e-17 60.3 1.5 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KPI45904.1 - 3.1e-08 34.1 0.0 1.1e-07 32.4 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KPI45904.1 - 0.0026 17.9 0.0 0.0082 16.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cytokin_check_N PF10407.4 KPI45905.1 - 3.5e-08 32.9 0.0 7.6e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus AAA PF00004.24 KPI45906.1 - 5.5e-14 52.5 0.0 1.9e-13 50.7 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KPI45906.1 - 5.4e-12 46.0 1.5 4e-11 43.2 0.2 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KPI45906.1 - 5.9e-10 39.3 0.0 1.7e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KPI45906.1 - 0.00048 20.0 0.0 0.00084 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.6 KPI45906.1 - 0.00077 19.1 0.0 0.0021 17.7 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal Arch_ATPase PF01637.13 KPI45906.1 - 0.0016 18.1 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 KPI45906.1 - 0.006 16.2 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 KPI45906.1 - 0.0071 16.0 0.0 0.032 13.9 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 KPI45906.1 - 0.011 14.6 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 KPI45906.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KPI45906.1 - 0.02 14.7 0.0 0.059 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KPI45906.1 - 0.02 15.6 0.0 0.036 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KPI45906.1 - 0.021 14.3 0.0 0.053 13.0 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 KPI45906.1 - 0.023 13.6 0.0 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF815 PF05673.8 KPI45906.1 - 0.029 13.2 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PIF1 PF05970.9 KPI45906.1 - 0.053 12.4 0.0 0.089 11.7 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_25 PF13481.1 KPI45906.1 - 0.054 12.8 0.0 0.17 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KPI45906.1 - 0.058 12.5 0.0 0.34 10.0 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KPI45906.1 - 0.06 12.7 0.0 0.6 9.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein cobW PF02492.14 KPI45906.1 - 0.097 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 KPI45906.1 - 0.098 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Guanylate_kin PF00625.16 KPI45906.1 - 0.12 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase AAA_18 PF13238.1 KPI45906.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.1 KPI45906.1 - 0.16 10.6 0.0 0.3 9.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain PBP PF01161.15 KPI45907.1 - 1.4e-16 60.6 0.0 2.1e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Mucin PF01456.12 KPI45907.1 - 0.0056 16.4 12.9 0.0056 16.4 8.9 1.8 2 1 0 2 2 2 1 Mucin-like glycoprotein DUF515 PF04415.7 KPI45907.1 - 2.1 6.5 3.9 2.7 6.1 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) TauD PF02668.11 KPI45909.1 - 1.6e-47 162.3 1.3 1.9e-45 155.5 0.9 2.1 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LRR_8 PF13855.1 KPI45910.1 - 1e-09 37.9 5.2 0.0016 18.1 0.1 6.0 5 2 1 6 6 6 2 Leucine rich repeat LRR_1 PF00560.28 KPI45910.1 - 2.6e-05 23.6 3.3 0.25 11.5 0.1 5.6 5 1 0 6 6 6 1 Leucine Rich Repeat LRR_4 PF12799.2 KPI45910.1 - 0.00019 20.9 7.3 0.0093 15.5 0.1 5.6 6 2 1 7 7 7 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KPI45910.1 - 0.00022 20.9 12.1 0.89 9.8 0.1 7.3 10 0 0 10 10 10 1 Leucine Rich repeat LRR_7 PF13504.1 KPI45910.1 - 0.19 12.0 12.4 2.4 8.7 0.2 6.3 8 1 0 8 8 8 0 Leucine rich repeat Borrelia_P83 PF05262.6 KPI45910.1 - 8.7 4.4 16.1 17 3.4 11.2 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein Mo-co_dimer PF03404.11 KPI45911.1 - 4.1e-54 181.7 0.4 8.3e-54 180.7 0.0 1.8 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 KPI45911.1 - 6.2e-48 162.4 0.0 1.1e-47 161.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 KPI45911.1 - 2.9e-29 101.1 0.0 5e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KPI45911.1 - 6.6e-25 87.7 0.0 1.3e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 KPI45911.1 - 5.9e-23 80.4 0.0 1.3e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KPI45911.1 - 0.00057 19.8 0.1 0.16 11.8 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain PH_10 PF15411.1 KPI45912.1 - 3.3e-23 82.0 0.1 6.1e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 KPI45912.1 - 3.1e-11 43.2 0.1 9.9e-11 41.5 0.0 1.9 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 KPI45912.1 - 5.6e-09 35.9 0.0 2.9e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 KPI45912.1 - 1.3e-07 31.2 4.3 2.4e-07 30.4 2.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KPI45912.1 - 0.00012 21.6 3.7 0.00021 20.9 2.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KPI45912.1 - 0.00032 20.3 1.2 0.00054 19.5 0.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI45912.1 - 0.00044 20.2 3.2 0.00082 19.3 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KPI45912.1 - 0.0041 16.7 3.7 0.0076 15.8 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KPI45912.1 - 0.024 14.7 1.1 0.052 13.6 0.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING-like PF08746.6 KPI45912.1 - 0.13 12.2 4.4 0.23 11.4 3.1 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 KPI45912.1 - 1.3 8.9 4.4 2.6 7.9 3.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.24 KPI45912.1 - 2.5 7.8 4.2 4.6 7.0 2.9 1.5 1 0 0 1 1 1 0 PHD-finger SKG6 PF08693.5 KPI45913.1 - 0.0075 15.5 0.2 0.019 14.2 0.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain WD40 PF00400.27 KPI45915.1 - 8.4e-19 66.6 20.0 1e-07 31.5 0.3 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat MFS_1 PF07690.11 KPI45916.1 - 7.1e-17 61.1 31.4 9.1e-15 54.2 21.6 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3353 PF11833.3 KPI45916.1 - 0.1 12.0 4.5 2.9 7.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3353) DUF3185 PF11381.3 KPI45916.1 - 1.5 8.6 6.8 16 5.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) CHAT PF12770.2 KPI45919.1 - 1e-28 100.2 0.1 2.2e-28 99.2 0.1 1.5 1 0 0 1 1 1 1 CHAT domain Peptidase_C50 PF03568.12 KPI45919.1 - 0.014 14.1 0.0 0.029 13.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C50 Ribosomal_L38e PF01781.13 KPI45920.1 - 1.2e-25 89.0 5.8 2.5e-25 87.9 4.0 1.5 1 1 0 1 1 1 1 Ribosomal L38e protein family Epimerase PF01370.16 KPI45921.1 - 1.3e-36 126.1 0.0 2e-35 122.3 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KPI45921.1 - 2e-13 50.0 0.0 3.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit NAD_binding_4 PF07993.7 KPI45921.1 - 1.3e-08 34.1 0.0 5e-08 32.1 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KPI45921.1 - 9e-07 27.8 0.0 0.036 12.7 0.0 2.6 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KPI45921.1 - 4.6e-06 25.7 0.0 4e-05 22.6 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 KPI45921.1 - 0.00057 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KPI45921.1 - 0.0011 18.8 0.1 0.002 18.0 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KPI45921.1 - 0.0054 16.7 0.0 0.2 11.6 0.0 2.6 2 1 0 2 2 2 1 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 KPI45921.1 - 0.047 13.0 0.1 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KPI45921.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KPI45923.1 - 2e-12 46.7 0.0 7.9e-12 44.8 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KPI45923.1 - 1.4e-08 34.4 0.0 4.4e-08 32.8 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KPI45923.1 - 0.0063 16.0 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_M24 PF00557.19 KPI45923.1 - 0.063 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Metallopeptidase family M24 DUF504 PF04457.7 KPI45923.1 - 0.088 12.9 0.0 0.33 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF504) Cnd2 PF05786.9 KPI45924.1 - 1.1e-177 592.8 4.3 1.6e-177 592.3 3.0 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 S-antigen PF05756.6 KPI45924.1 - 0.13 12.2 2.5 0.42 10.6 1.7 1.8 1 0 0 1 1 1 0 S-antigen protein 4HBT PF03061.17 KPI45925.1 - 4e-08 33.2 0.0 6.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Cornichon PF03311.9 KPI45926.1 - 2.8e-54 182.6 12.2 3.1e-54 182.5 8.5 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M50 PF02163.17 KPI45926.1 - 1.4 7.8 5.1 1.7 7.5 3.6 1.2 1 0 0 1 1 1 0 Peptidase family M50 DUF1769 PF08588.5 KPI45927.1 - 1.4e-30 104.9 0.3 3.2e-30 103.8 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) GST_N_3 PF13417.1 KPI45929.1 - 2.6e-14 53.2 0.0 4.9e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KPI45929.1 - 5.3e-10 39.1 0.0 9.6e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KPI45929.1 - 3.6e-08 33.2 0.0 1.3e-07 31.5 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KPI45929.1 - 2e-07 30.7 0.1 8.4e-07 28.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KPI45929.1 - 1.5e-06 28.2 0.0 3.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KPI45929.1 - 0.0014 19.0 0.0 0.0022 18.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 KPI45930.1 - 3.5e-33 114.7 29.3 3.5e-33 114.7 20.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KPI45930.1 - 1.3e-10 40.4 12.8 1.3e-10 40.4 8.8 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter bZIP_1 PF00170.16 KPI45931.1 - 3.7e-11 42.7 15.6 4.8e-11 42.4 9.4 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KPI45931.1 - 0.00015 21.4 11.4 0.00022 20.9 6.6 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 KPI45931.1 - 0.0005 20.3 4.1 0.0013 19.0 2.8 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor Pkinase PF00069.20 KPI45932.1 - 1e-21 77.2 0.0 2e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KPI45932.1 - 2e-08 33.6 0.0 2.1e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DAO PF01266.19 KPI45933.1 - 7.8e-36 123.7 0.0 1.3e-35 122.9 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KPI45933.1 - 0.0029 17.3 0.1 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KPI45933.1 - 0.0031 17.6 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KPI45933.1 - 0.0049 16.8 0.1 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Tropomyosin_1 PF12718.2 KPI45934.1 - 1.6e-44 151.2 40.1 2.1e-44 150.8 27.8 1.2 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 KPI45934.1 - 2.2e-09 36.7 34.8 3.3e-06 26.3 8.9 2.9 1 1 2 3 3 3 2 Tropomyosin bZIP_1 PF00170.16 KPI45934.1 - 0.0015 18.4 35.0 0.4 10.6 3.2 5.1 1 1 4 5 5 5 2 bZIP transcription factor BLOC1_2 PF10046.4 KPI45934.1 - 0.0027 17.8 24.9 0.78 9.9 2.8 3.2 1 1 2 3 3 3 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 KLRAQ PF10205.4 KPI45934.1 - 0.003 17.5 11.7 0.003 17.5 8.1 2.9 1 1 2 3 3 3 1 Predicted coiled-coil domain-containing protein ADIP PF11559.3 KPI45934.1 - 0.0043 16.9 35.4 0.0046 16.8 11.1 2.4 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding WXG100 PF06013.7 KPI45934.1 - 0.0063 16.4 17.2 0.08 12.9 2.6 3.3 2 1 1 3 3 3 2 Proteins of 100 residues with WXG DUF4200 PF13863.1 KPI45934.1 - 0.012 15.5 33.9 0.21 11.5 11.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) ATG16 PF08614.6 KPI45934.1 - 0.012 15.4 32.8 1.2 8.9 8.9 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3086 PF11285.3 KPI45934.1 - 0.013 14.3 17.0 0.008 15.0 9.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) Cep57_CLD_2 PF14197.1 KPI45934.1 - 0.014 15.3 34.6 0.019 14.8 8.1 4.0 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 APG6 PF04111.7 KPI45934.1 - 0.015 14.4 37.6 0.15 11.0 10.8 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 KPI45934.1 - 0.017 15.0 36.9 0.025 14.4 6.2 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 KPI45934.1 - 0.019 14.7 41.2 0.22 11.3 9.5 3.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KPI45934.1 - 0.027 14.0 32.6 0.53 9.8 16.7 2.3 1 1 1 2 2 2 0 IncA protein DUF4140 PF13600.1 KPI45934.1 - 0.028 14.8 24.1 0.04 14.3 3.5 3.0 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Filament PF00038.16 KPI45934.1 - 0.039 13.4 30.0 0.33 10.3 7.7 2.0 1 1 1 2 2 2 0 Intermediate filament protein GAS PF13851.1 KPI45934.1 - 0.046 12.9 33.5 0.12 11.5 23.2 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mod_r PF07200.8 KPI45934.1 - 0.085 12.7 30.9 1.3 8.9 13.7 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IFT46_B_C PF12317.3 KPI45934.1 - 0.1 11.9 11.5 0.013 14.9 4.2 1.8 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Spc7 PF08317.6 KPI45934.1 - 0.11 11.1 31.2 0.016 13.8 13.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein CCDC155 PF14662.1 KPI45934.1 - 0.13 11.8 35.2 0.15 11.6 16.6 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Fib_alpha PF08702.5 KPI45934.1 - 0.14 12.3 21.3 0.48 10.5 5.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PilJ PF13675.1 KPI45934.1 - 0.15 12.3 17.1 0.17 12.1 3.2 2.9 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3287 PF11690.3 KPI45934.1 - 0.2 11.7 17.6 0.091 12.8 0.8 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) FlaC_arch PF05377.6 KPI45934.1 - 0.21 11.5 19.6 0.25 11.2 1.6 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Striatin PF08232.7 KPI45934.1 - 0.27 11.5 29.8 0.54 10.5 12.2 2.3 1 1 1 2 2 2 0 Striatin family Lebercilin PF15619.1 KPI45934.1 - 0.38 10.1 37.5 0.45 9.9 11.0 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HALZ PF02183.13 KPI45934.1 - 0.7 9.6 25.1 2 8.2 1.3 4.6 4 1 0 4 4 4 0 Homeobox associated leucine zipper DUF4600 PF15372.1 KPI45934.1 - 0.83 9.8 25.7 0.92 9.7 1.5 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) DUF4201 PF13870.1 KPI45934.1 - 0.89 8.9 31.0 4.6 6.6 7.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.7 KPI45934.1 - 0.92 9.2 39.5 0.67 9.7 11.5 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.3 KPI45934.1 - 0.97 9.1 33.4 0.25 11.0 9.1 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF2353 PF09789.4 KPI45934.1 - 1.4 8.0 27.3 15 4.7 18.7 2.0 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF812 PF05667.6 KPI45934.1 - 1.9 6.8 27.9 3 6.2 19.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DivIC PF04977.10 KPI45934.1 - 2.1 7.8 32.7 0.55 9.7 4.2 4.3 2 1 2 4 4 4 0 Septum formation initiator Syntaxin-6_N PF09177.6 KPI45934.1 - 2.2 8.7 22.0 2.3 8.6 3.9 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Jnk-SapK_ap_N PF09744.4 KPI45934.1 - 2.2 8.2 31.0 0.074 13.0 14.5 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Nup54 PF13874.1 KPI45934.1 - 2.3 7.8 25.7 7.1 6.2 7.0 2.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 bZIP_2 PF07716.10 KPI45934.1 - 2.4 8.0 35.5 1.1 9.0 1.0 5.4 2 2 3 5 5 5 0 Basic region leucine zipper ERM PF00769.14 KPI45934.1 - 2.5 7.5 39.5 1 8.8 11.9 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HOOK PF05622.7 KPI45934.1 - 2.7 5.6 31.1 9.3 3.9 21.5 1.7 1 1 0 1 1 1 0 HOOK protein DUF1664 PF07889.7 KPI45934.1 - 3 7.6 18.4 4.3 7.1 3.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.7 KPI45934.1 - 3.8 7.2 21.7 0.26 11.0 3.5 2.1 1 1 1 2 2 2 0 Laminin Domain II Vps5 PF09325.5 KPI45934.1 - 4.2 6.5 24.9 0.053 12.7 6.7 2.8 1 1 2 3 3 3 0 Vps5 C terminal like DUF2094 PF09867.4 KPI45934.1 - 4.3 7.2 8.9 2.5 7.9 0.2 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2094) Reo_sigmaC PF04582.7 KPI45934.1 - 4.3 6.4 6.2 12 5.0 0.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4482 PF14818.1 KPI45934.1 - 5.2 7.7 27.0 0.15 12.6 3.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Seryl_tRNA_N PF02403.17 KPI45934.1 - 5.4 7.0 30.9 4.5 7.3 7.2 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF724 PF05266.9 KPI45934.1 - 6 6.4 31.5 3.5 7.2 7.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF3584 PF12128.3 KPI45934.1 - 6.5 3.9 33.6 12 3.0 23.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF972 PF06156.8 KPI45934.1 - 6.6 7.1 30.3 4.8 7.5 1.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) HSP70 PF00012.15 KPI45934.1 - 9.3 4.0 22.2 5.4 4.7 14.3 1.3 1 1 0 1 1 1 0 Hsp70 protein Glyco_hydro_47 PF01532.15 KPI45935.1 - 3.4e-148 494.0 0.4 4.1e-148 493.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 bZIP_2 PF07716.10 KPI45937.1 - 1.4e-05 24.7 7.4 2.4e-05 24.0 5.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KPI45937.1 - 0.017 15.3 5.2 0.031 14.5 3.6 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.16 KPI45937.1 - 0.047 13.6 6.8 0.076 12.9 4.7 1.3 1 0 0 1 1 1 0 bZIP transcription factor Arrestin_N PF00339.24 KPI45938.1 - 3e-13 49.8 0.0 1.1e-12 48.0 0.0 1.9 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.10 KPI45938.1 - 0.15 10.8 0.0 0.66 8.7 0.0 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 IBR PF01485.16 KPI45939.1 - 0.00014 21.6 7.8 0.00014 21.6 5.4 4.8 4 2 1 5 5 5 2 IBR domain zf-RING_4 PF14570.1 KPI45939.1 - 0.016 14.8 2.6 0.016 14.8 1.8 5.1 5 1 0 5 5 5 0 RING/Ubox like zinc-binding domain INSIG PF07281.7 KPI45940.1 - 3.9e-16 58.9 0.0 5.1e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) Glyco_hydro_16 PF00722.16 KPI45941.1 - 2e-40 138.0 4.6 3.4e-40 137.3 3.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF423 PF04241.10 KPI45943.1 - 3.2e-13 49.3 1.2 5.9e-13 48.5 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF423) RhoGAP PF00620.22 KPI45944.1 - 4e-13 49.2 0.6 9.5e-13 48.0 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KPI45944.1 - 1.2e-12 47.8 0.1 3.4e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 KPI45944.1 - 2.9e-09 36.5 0.0 5.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) IGR PF09597.5 KPI45945.1 - 4e-20 71.4 0.6 6.7e-20 70.7 0.4 1.4 1 0 0 1 1 1 1 IGR protein motif Amidase PF01425.16 KPI45946.1 - 3.8e-69 233.6 0.4 6.7e-68 229.5 0.2 2.1 1 1 0 1 1 1 1 Amidase WD40 PF00400.27 KPI45947.1 - 5.2e-37 124.4 29.5 3.5e-05 23.5 1.8 11.1 11 0 0 11 11 11 10 WD domain, G-beta repeat CAP PF00188.21 KPI45948.1 - 6.1e-17 62.2 0.5 1.2e-16 61.2 0.4 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MCM PF00493.18 KPI45949.1 - 1e-132 442.0 0.0 4.4e-132 439.9 0.0 1.8 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KPI45949.1 - 1.1e-29 103.3 0.2 3.6e-29 101.7 0.1 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KPI45949.1 - 4.8e-07 29.1 0.0 5.3e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KPI45949.1 - 7.1e-06 25.7 0.0 3.5e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KPI45949.1 - 0.047 13.2 0.0 0.17 11.4 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MutS_V PF00488.16 KPI45950.1 - 3e-71 239.5 0.1 4.8e-71 238.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KPI45950.1 - 6.1e-30 104.5 0.7 6.1e-30 104.5 0.5 2.1 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 KPI45950.1 - 2.9e-10 40.2 0.1 7.5e-10 38.8 0.0 1.8 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 KPI45950.1 - 2.6e-09 37.2 0.1 8e-09 35.6 0.1 1.8 1 0 0 1 1 1 1 MutS domain II AAA_22 PF13401.1 KPI45950.1 - 0.11 12.6 0.0 0.39 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain RhoGAP PF00620.22 KPI45952.1 - 1.3e-39 135.2 0.9 2.9e-39 134.1 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 KPI45952.1 - 1.4e-10 41.2 0.0 2.9e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KPI45952.1 - 0.0002 21.6 1.2 0.0004 20.6 0.1 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 KPI45952.1 - 0.23 11.5 0.1 0.77 9.8 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain DUF221 PF02714.10 KPI45953.1 - 1.9e-92 309.5 19.9 1.9e-92 309.5 13.8 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KPI45953.1 - 1.3e-39 135.2 1.5 1.3e-39 135.2 1.1 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KPI45953.1 - 1.7e-19 70.1 0.7 2.9e-19 69.3 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 KPI45953.1 - 2e-05 24.4 0.0 0.23 11.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Isochorismatase PF00857.15 KPI45954.1 - 9.8e-24 84.2 0.2 1.2e-23 83.9 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family SET PF00856.23 KPI45956.1 - 8.2e-13 48.9 0.1 6.7e-11 42.7 0.0 2.7 2 0 0 2 2 2 2 SET domain BTB PF00651.26 KPI45957.1 - 2.5e-09 37.1 0.0 8.1e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain BNR PF02012.15 KPI45958.1 - 6.1e-11 40.4 15.9 0.18 11.7 0.2 6.1 5 0 0 5 5 5 5 BNR/Asp-box repeat BNR_2 PF13088.1 KPI45958.1 - 0.00071 18.9 3.9 2.9 7.0 0.4 3.6 1 1 0 2 2 2 1 BNR repeat-like domain Mo-co_dimer PF03404.11 KPI45958.1 - 0.021 14.4 7.9 6.7 6.3 0.0 4.6 3 2 2 5 5 5 0 Mo-co oxidoreductase dimerisation domain UBA_4 PF14555.1 KPI45959.1 - 0.12 11.9 1.8 7.4 6.2 0.0 2.6 2 0 0 2 2 2 0 UBA-like domain YEATS PF03366.11 KPI45960.1 - 6.9e-17 60.9 0.2 1.3e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 YEATS family AICARFT_IMPCHas PF01808.13 KPI45961.1 - 2.4e-85 286.4 0.8 1.3e-63 215.0 0.0 2.1 2 0 0 2 2 2 2 AICARFT/IMPCHase bienzyme MGS PF02142.17 KPI45961.1 - 3.1e-23 81.5 0.0 5.7e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain GFA PF04828.9 KPI45963.1 - 5.9e-19 67.8 0.3 9.5e-19 67.1 0.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.11 KPI45963.1 - 0.14 11.8 2.4 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Prim_Zn_Ribbon PF08273.7 KPI45963.1 - 0.64 10.1 0.0 0.64 10.1 0.0 3.0 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase Auto_anti-p27 PF06677.7 KPI45963.1 - 0.69 9.7 0.0 0.69 9.7 0.0 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) HCV_NS5a_1a PF08300.8 KPI45963.1 - 3.1 7.7 7.1 0.6 10.0 1.8 2.1 2 1 1 3 3 3 0 Hepatitis C virus non-structural 5a zinc finger domain Sulfotransfer_3 PF13469.1 KPI45964.1 - 0.00016 22.6 0.3 0.00023 22.1 0.2 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sugar_tr PF00083.19 KPI45965.1 - 1.4e-79 267.8 23.4 1.6e-79 267.5 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI45965.1 - 2.5e-16 59.3 31.7 2.5e-16 59.3 22.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 KPI45966.1 - 3e-18 66.3 9.4 1.4e-16 60.8 2.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.27 KPI45968.1 - 0.0029 17.4 18.8 0.53 10.2 1.1 8.2 9 1 1 10 10 10 2 WD domain, G-beta repeat TFIIF_alpha PF05793.7 KPI45968.1 - 0.11 10.8 1.9 0.18 10.1 1.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Fungal_trans_2 PF11951.3 KPI45969.1 - 4.3e-06 25.5 0.3 6e-06 25.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cut8_N PF14482.1 KPI45971.1 - 1.8 8.6 7.8 0.68 9.9 0.1 2.8 2 1 0 2 2 2 0 Cut8 proteasome-binding domain Frag1 PF10277.4 KPI45972.1 - 2.3e-46 157.9 17.2 2.7e-46 157.7 11.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family WD40 PF00400.27 KPI45973.1 - 3.2e-30 102.9 8.6 1.5e-06 27.8 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KPI45973.1 - 0.022 13.5 0.0 0.16 10.7 0.0 2.1 2 1 0 2 2 2 0 Nup133 N terminal like Med5 PF08689.5 KPI45974.1 - 1.8e-77 261.0 0.0 9.4e-77 258.6 0.0 2.0 2 1 0 2 2 2 1 Mediator complex subunit Med5 DUF89 PF01937.14 KPI45975.1 - 9.9e-106 353.5 1.0 1.1e-105 353.3 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Fasciclin PF02469.17 KPI45976.1 - 1.2e-43 148.1 0.4 1.2e-26 93.1 0.4 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF348 PF03990.9 KPI45976.1 - 0.1 12.1 0.7 0.23 11.0 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF348) PALP PF00291.20 KPI45977.1 - 8e-73 245.3 0.3 1e-72 244.9 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KPI45977.1 - 2.7e-45 151.8 0.0 1e-21 76.3 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase BTK PF00779.14 KPI45981.1 - 0.00084 18.9 7.4 1.4 8.5 0.1 3.2 3 0 0 3 3 3 3 BTK motif Nodulin_late PF07127.6 KPI45981.1 - 0.0024 17.9 0.6 6.4 6.9 0.0 3.0 3 0 0 3 3 3 2 Late nodulin protein Trypan_PARP PF05887.6 KPI45981.1 - 0.0095 15.7 34.1 0.17 11.7 23.9 1.9 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) Abhydrolase_3 PF07859.8 KPI45982.1 - 9.1e-41 139.7 0.1 5.3e-32 111.1 0.1 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KPI45982.1 - 1.7e-15 56.6 0.0 3.1e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 KPI45982.1 - 0.00024 19.9 0.5 0.022 13.4 0.0 2.5 3 0 0 3 3 3 2 Carboxylesterase family Abhydrolase_5 PF12695.2 KPI45982.1 - 0.0005 19.8 0.1 0.0027 17.4 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family SUR7 PF06687.7 KPI45983.1 - 4.3e-42 144.0 16.3 5.3e-42 143.7 11.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 KPI45983.1 - 0.00084 19.2 6.4 0.00084 19.2 4.5 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 DUF3899 PF13038.1 KPI45983.1 - 0.026 14.6 4.4 4.4 7.5 0.8 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) Shisa PF13908.1 KPI45983.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.7 3 1 1 4 4 4 0 Wnt and FGF inhibitory regulator YwiC PF14256.1 KPI45983.1 - 0.22 11.5 8.7 0.22 11.6 4.7 1.9 2 0 0 2 2 2 0 YwiC-like protein DUF4131 PF13567.1 KPI45983.1 - 8.5 5.7 8.9 17 4.7 4.5 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) WD40 PF00400.27 KPI45984.1 - 1.7e-30 103.7 6.4 1.2e-07 31.2 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 KPI45984.1 - 2.4e-17 62.7 0.0 4.3e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Glycohydro_20b2 PF14845.1 KPI45985.1 - 3.9e-21 76.0 0.0 4.9e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KPI45985.1 - 1.9e-08 34.8 0.5 4.5e-08 33.6 0.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Form_Nir_trans PF01226.12 KPI45986.1 - 2.3e-55 187.2 20.7 2.6e-55 187.0 14.3 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Acetyltransf_1 PF00583.19 KPI45987.1 - 1.5e-14 53.7 0.1 2.7e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KPI45987.1 - 1.9e-06 27.5 0.1 3.6e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KPI45987.1 - 0.00037 20.5 0.0 0.00057 19.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KPI45987.1 - 0.0057 16.7 0.0 0.0094 16.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KPI45987.1 - 0.012 15.5 0.1 0.018 14.8 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acyl_transf_3 PF01757.17 KPI45988.1 - 2.7e-27 95.4 24.8 2e-26 92.6 17.2 2.1 1 1 0 1 1 1 1 Acyltransferase family Proteasome PF00227.21 KPI45989.1 - 2.5e-47 160.6 0.5 3e-47 160.3 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit RhaA PF06134.6 KPI45992.1 - 0.1 11.4 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 L-rhamnose isomerase (RhaA) Glyco_transf_20 PF00982.16 KPI45993.1 - 8.9e-137 456.4 0.1 2.2e-134 448.5 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KPI45993.1 - 3.4e-36 124.3 0.0 6.1e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase zf-LYAR PF08790.6 KPI45994.1 - 7.7e-14 51.0 3.0 7.7e-14 51.0 2.1 2.2 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DUF3176 PF11374.3 KPI45995.1 - 8.9e-09 35.2 2.3 2.1e-08 34.0 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) AMP-binding PF00501.23 KPI45996.1 - 9.4e-69 231.7 0.0 1.1e-68 231.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI45996.1 - 4.4e-15 56.3 0.1 1.4e-14 54.8 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Beta-lactamase PF00144.19 KPI45999.1 - 2.5e-23 82.6 0.2 3e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase FLO_LFY PF01698.11 KPI46000.1 - 0.73 8.6 4.4 0.81 8.4 3.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein C2 PF00168.25 KPI46001.1 - 2e-10 40.3 0.0 3.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain Nop25 PF09805.4 KPI46002.1 - 8.8e-28 97.0 11.9 8.8e-28 97.0 8.3 2.3 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) Mitofilin PF09731.4 KPI46003.1 - 1.8e-129 433.0 18.3 7e-129 431.1 12.7 1.7 1 1 0 1 1 1 1 Mitochondrial inner membrane protein 4HB_MCP_1 PF12729.2 KPI46003.1 - 3.3 7.0 8.5 6.3 6.0 5.9 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction OmpH PF03938.9 KPI46003.1 - 4.2 7.2 15.6 1.4 8.8 7.0 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CDC37_N PF03234.9 KPI46003.1 - 5.1 7.3 12.2 0.81 9.9 5.4 2.0 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding TMF_DNA_bd PF12329.3 KPI46004.1 - 0.27 11.0 6.7 0.38 10.5 1.8 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding YlqD PF11068.3 KPI46004.1 - 2.6 8.0 11.6 0.94 9.5 3.7 2.4 2 0 0 2 2 2 0 YlqD protein DUF1705 PF08019.7 KPI46005.1 - 4.7 6.6 12.2 3.3 7.2 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1705) Dsl1_C PF11989.3 KPI46006.1 - 1.1e-06 28.0 1.8 1.8e-06 27.3 0.2 2.2 2 1 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal DUF2046 PF09755.4 KPI46006.1 - 0.00016 20.7 0.3 0.00028 19.8 0.2 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Tup_N PF08581.5 KPI46006.1 - 0.00026 21.0 1.0 0.0065 16.6 0.2 3.2 2 0 0 2 2 2 1 Tup N-terminal LOH1CR12 PF10158.4 KPI46006.1 - 0.054 13.2 0.4 0.27 11.0 0.1 2.4 2 0 0 2 2 2 0 Tumour suppressor protein Seryl_tRNA_N PF02403.17 KPI46006.1 - 0.18 11.8 3.6 0.56 10.2 0.3 3.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Aldolase_II PF00596.16 KPI46007.1 - 2.5e-44 151.0 1.0 4.8e-44 150.1 0.7 1.5 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Transketolase_N PF00456.16 KPI46008.1 - 4e-117 390.7 0.0 7.4e-117 389.8 0.0 1.4 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KPI46008.1 - 3.2e-42 144.0 0.2 6.4e-42 143.0 0.1 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 KPI46008.1 - 3.7e-07 29.3 0.0 4e-06 25.9 0.0 2.1 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 KPI46008.1 - 3.6e-06 26.9 0.0 1.3e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.15 KPI46008.1 - 0.062 12.0 0.1 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component Melibiase PF02065.13 KPI46009.1 - 2.1e-30 105.7 0.0 1.4e-15 56.9 0.0 2.1 1 1 1 2 2 2 2 Melibiase SsgA PF04686.7 KPI46009.1 - 0.071 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA p450 PF00067.17 KPI46010.1 - 4.9e-60 203.3 0.0 6.7e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase PF00903.20 KPI46011.1 - 7.6e-24 84.1 1.5 9.5e-16 57.9 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KPI46011.1 - 1.3e-16 60.5 0.4 5e-07 29.6 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KPI46011.1 - 2.8e-12 47.1 0.1 1.3e-06 28.9 0.0 2.8 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 KPI46011.1 - 1.1e-08 35.1 1.6 0.0015 18.5 0.6 3.9 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KPI46011.1 - 1.2e-08 34.9 0.4 1.1e-05 25.3 0.2 3.1 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal HSA PF07529.8 KPI46012.1 - 2.9e-16 58.9 2.4 2.9e-16 58.9 1.6 3.0 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.1 KPI46012.1 - 8.2e-14 51.4 0.3 2.9e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KPI46012.1 - 0.0068 16.4 0.0 0.02 14.9 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Peptidase_M19 PF01244.16 KPI46013.1 - 2.4e-93 312.5 0.0 2.8e-93 312.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amino_oxidase PF01593.19 KPI46014.1 - 1e-31 110.5 0.0 5.5e-30 104.8 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KPI46014.1 - 4.1e-10 39.5 0.0 1.3e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 KPI46014.1 - 0.00015 21.3 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KPI46014.1 - 0.00015 21.8 0.0 0.00031 20.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KPI46014.1 - 0.00036 19.1 0.2 0.00067 18.2 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KPI46014.1 - 0.00058 19.0 0.2 0.00091 18.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KPI46014.1 - 0.018 13.8 0.5 0.028 13.2 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 KPI46014.1 - 0.051 13.3 0.2 9.4 5.9 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 KPI46014.1 - 0.073 13.4 0.1 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KPI46014.1 - 0.078 12.0 0.4 0.14 11.2 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 KPI46014.1 - 0.11 12.3 0.4 2.4 7.9 0.5 2.1 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GTP_EFTU PF00009.22 KPI46015.1 - 2.6e-33 115.0 0.0 4.4e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KPI46015.1 - 0.0046 16.8 0.0 0.0094 15.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KPI46015.1 - 0.042 13.6 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Dynamin family CTP_transf_2 PF01467.21 KPI46016.1 - 0.0033 17.4 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 KPI46016.1 - 0.18 11.4 1.1 0.44 10.1 0.5 1.8 1 1 1 2 2 2 0 FAD synthetase BSD PF03909.12 KPI46017.1 - 2.4e-13 49.6 0.1 4.6e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 BSD domain DUF2868 PF11067.3 KPI46017.1 - 1.4 8.0 7.6 1.7 7.7 2.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2868) Suf PF05843.9 KPI46017.1 - 7.4 6.2 7.1 0.41 10.3 0.4 2.0 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) Peptidase_M24 PF00557.19 KPI46018.1 - 3.9e-38 131.1 0.0 5.1e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 GPI-anchored PF10342.4 KPI46018.1 - 0.023 15.1 0.1 0.069 13.6 0.0 1.8 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ufd2P_core PF10408.4 KPI46019.1 - 0.044 12.0 1.1 0.064 11.4 0.8 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core TORC_N PF12884.2 KPI46019.1 - 0.076 13.5 5.0 0.11 13.0 1.5 2.7 2 0 0 2 2 2 0 Transducer of regulated CREB activity, N terminus Sugar_tr PF00083.19 KPI46020.1 - 1.7e-28 99.4 41.5 1.1e-14 53.8 17.7 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KPI46020.1 - 3.8e-06 25.8 51.3 0.00045 19.0 2.9 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily p450 PF00067.17 KPI46021.1 - 3.4e-56 190.6 0.0 4.2e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AP_endonuc_2 PF01261.19 KPI46022.1 - 4.4e-25 88.2 0.1 6.6e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MFS_1 PF07690.11 KPI46023.1 - 2.6e-07 29.7 46.4 0.0021 16.8 30.8 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily Herpes_gE PF02480.11 KPI46023.1 - 0.34 9.1 1.1 0.35 9.0 0.0 1.5 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E FAA_hydrolase PF01557.13 KPI46025.1 - 2.8e-44 151.1 0.0 3.9e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KPI46025.1 - 4.6e-26 90.9 0.0 1.1e-24 86.4 0.0 2.2 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal RhoGAP PF00620.22 KPI46028.1 - 6.1e-30 103.8 0.0 1e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Peptidase_C48 PF02902.14 KPI46029.1 - 2e-15 56.9 0.2 6.5e-15 55.3 0.2 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Methyltransf_4 PF02390.12 KPI46030.1 - 9.9e-41 138.9 0.0 1.6e-39 135.0 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KPI46030.1 - 2e-05 25.1 0.0 3.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KPI46030.1 - 0.0032 17.8 0.0 0.012 16.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KPI46030.1 - 0.026 14.5 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KPI46030.1 - 0.031 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KPI46030.1 - 0.065 13.7 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 KPI46030.1 - 0.13 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Fungal_trans PF04082.13 KPI46031.1 - 5.4e-05 22.1 0.0 8.7e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain EVE PF01878.13 KPI46032.1 - 8.9e-47 158.7 0.4 8.9e-47 158.7 0.3 1.5 2 0 0 2 2 2 1 EVE domain LSM PF01423.17 KPI46033.1 - 3.8e-20 71.1 0.0 4.7e-20 70.9 0.0 1.0 1 0 0 1 1 1 1 LSM domain HD PF01966.17 KPI46034.1 - 2.6e-05 24.2 0.0 3.7e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 HD domain SWI-SNF_Ssr4 PF08549.5 KPI46035.1 - 4.1e-117 392.2 44.9 2.9e-56 191.1 22.5 4.7 1 1 2 3 3 3 3 Fungal domain of unknown function (DUF1750) tRNA-synt_1b PF00579.20 KPI46036.1 - 3.4e-62 210.2 0.0 4.3e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) End_N_terminal PF12218.3 KPI46036.1 - 0.035 13.5 0.0 0.075 12.5 0.0 1.6 1 1 0 1 1 1 0 N terminal extension of bacteriophage endosialidase NACHT PF05729.7 KPI46037.1 - 2.3e-10 40.3 0.1 4.6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain zf-C2H2 PF00096.21 KPI46037.1 - 6.9e-09 35.5 21.4 0.0014 18.8 1.2 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type AAA_16 PF13191.1 KPI46037.1 - 8.9e-09 35.5 0.1 9.9e-08 32.1 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain zf-C2H2_4 PF13894.1 KPI46037.1 - 3e-08 33.4 17.6 0.077 13.3 1.2 5.1 5 0 0 5 5 4 4 C2H2-type zinc finger AAA_22 PF13401.1 KPI46037.1 - 7.2e-05 22.9 0.0 0.00024 21.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain zf-C2H2_jaz PF12171.3 KPI46037.1 - 0.00016 21.7 11.4 0.37 10.9 1.2 4.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KPI46037.1 - 0.00019 21.5 9.1 0.4 10.9 0.3 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 KPI46037.1 - 0.0033 17.0 1.6 0.17 11.5 0.2 2.9 2 0 0 2 2 2 1 zinc-finger of a C2HC-type DUF2075 PF09848.4 KPI46037.1 - 0.0094 14.9 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 KPI46037.1 - 0.011 15.8 0.1 0.042 14.0 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) zf-H2C2_2 PF13465.1 KPI46037.1 - 0.021 15.0 0.5 0.021 15.0 0.4 5.6 6 0 0 6 6 5 0 Zinc-finger double domain AAA_14 PF13173.1 KPI46037.1 - 0.054 13.3 0.0 0.47 10.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KPI46037.1 - 0.055 12.3 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 KPI46037.1 - 0.061 13.0 0.1 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 KPI46037.1 - 0.077 13.8 0.0 0.5 11.1 0.0 2.6 1 0 0 1 1 1 0 AAA domain Zn_ribbon_recom PF13408.1 KPI46037.1 - 0.16 12.2 1.4 0.48 10.7 0.9 1.8 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain NTPase_1 PF03266.10 KPI46037.1 - 0.17 11.5 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 NTPase zf-DNL PF05180.7 KPI46037.1 - 0.21 11.2 2.9 0.61 9.8 0.5 2.6 3 0 0 3 3 3 0 DNL zinc finger Aminotran_1_2 PF00155.16 KPI46039.1 - 7.6e-44 150.1 0.0 9.2e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KPI46039.1 - 8.1e-11 41.2 0.0 2.3e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KPI46039.1 - 1.2e-10 40.9 0.0 2.8e-10 39.7 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KPI46039.1 - 5.5e-09 34.7 0.0 8.5e-09 34.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KPI46039.1 - 2e-06 27.1 0.0 5e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 KPI46039.1 - 0.028 13.0 0.1 0.08 11.5 0.0 1.6 1 1 0 1 1 1 0 Allinase Met_gamma_lyase PF06838.6 KPI46039.1 - 0.11 10.7 0.0 0.34 9.1 0.0 1.7 2 0 0 2 2 2 0 Methionine gamma-lyase RTA1 PF04479.8 KPI46040.1 - 1.9e-42 145.2 3.3 2.7e-42 144.8 2.3 1.1 1 0 0 1 1 1 1 RTA1 like protein DctQ PF04290.7 KPI46040.1 - 1.9 8.2 15.7 0.63 9.8 1.9 3.3 2 2 2 4 4 4 0 Tripartite ATP-independent periplasmic transporters, DctQ component CorA PF01544.13 KPI46041.1 - 0.00035 19.7 0.7 0.00069 18.7 0.0 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein PK PF00224.16 KPI46042.1 - 3.8e-166 551.9 2.0 4.8e-166 551.6 1.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KPI46042.1 - 3.1e-28 97.6 0.0 7.4e-28 96.4 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KPI46042.1 - 0.00011 21.1 0.3 0.00019 20.3 0.2 1.4 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 KPI46042.1 - 0.045 12.6 0.0 0.2 10.4 0.0 1.8 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Calcipressin PF04847.7 KPI46042.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Calcipressin SNF5 PF04855.7 KPI46043.1 - 3.3e-69 233.0 0.3 6.6e-69 232.0 0.2 1.5 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Totivirus_coat PF05518.6 KPI46043.1 - 4.1 5.0 7.3 6.2 4.5 5.1 1.2 1 0 0 1 1 1 0 Totivirus coat protein TMEM154 PF15102.1 KPI46044.1 - 0.0043 16.7 0.6 0.022 14.4 0.0 2.4 2 0 0 2 2 2 1 TMEM154 protein family DUF1191 PF06697.7 KPI46044.1 - 0.019 13.7 0.0 0.036 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DNA_pol_A_exo1 PF01612.15 KPI46044.1 - 0.081 12.4 0.1 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 3'-5' exonuclease DUF3094 PF11293.3 KPI46044.1 - 0.41 10.1 2.7 0.96 8.9 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) TrbL PF04610.9 KPI46044.1 - 0.58 9.8 2.2 0.93 9.1 1.5 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein HET PF06985.6 KPI46045.1 - 2.5e-24 85.9 0.1 1.7e-23 83.3 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 KPI46046.1 - 5.2e-31 107.6 28.9 1.3e-30 106.3 20.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KPI46046.1 - 2.6e-05 22.8 14.0 0.00036 19.0 9.4 2.7 1 1 1 2 2 2 1 MFS/sugar transport protein DUF3169 PF11368.3 KPI46046.1 - 0.08 12.1 0.1 0.08 12.1 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) PMM PF03332.8 KPI46047.1 - 1.1e-96 322.6 0.0 1.3e-96 322.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KPI46047.1 - 0.00091 18.8 0.0 0.019 14.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 KPI46047.1 - 0.11 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein HisG PF01634.13 KPI46049.1 - 6.8e-52 175.3 0.1 1.1e-51 174.5 0.1 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 KPI46049.1 - 6.2e-27 93.3 0.5 1.4e-26 92.1 0.4 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 KPI46049.1 - 0.00064 19.3 0.1 0.0013 18.4 0.0 1.6 1 1 0 1 1 1 1 NMT1/THI5 like DnaJ PF00226.26 KPI46050.1 - 4.9e-21 74.2 1.4 8.7e-21 73.4 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain Gly-zipper_OmpA PF13436.1 KPI46050.1 - 0.00013 21.6 0.7 0.00026 20.6 0.5 1.6 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain DUF456 PF04306.8 KPI46050.1 - 0.036 14.1 0.5 0.058 13.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.4 KPI46050.1 - 0.1 12.7 6.3 0.21 11.7 4.3 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.10 KPI46050.1 - 0.15 11.7 16.6 1.4 8.6 2.9 2.5 1 1 1 2 2 2 0 Glycine zipper 2TM domain DUF1183 PF06682.7 KPI46050.1 - 0.3 10.6 4.5 0.52 9.8 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Gly-zipper_Omp PF13488.1 KPI46050.1 - 0.86 9.2 14.4 2.5 7.7 9.8 1.9 1 1 1 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.1 KPI46050.1 - 0.92 9.0 16.2 0.7 9.4 9.5 2.0 1 1 1 2 2 2 0 YMGG-like Gly-zipper Sugar_tr PF00083.19 KPI46051.1 - 1e-70 238.5 23.6 1.3e-70 238.2 16.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KPI46051.1 - 3.9e-21 75.1 19.5 3.9e-21 75.1 13.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Macoilin PF09726.4 KPI46052.1 - 0.044 12.0 11.4 0.059 11.6 7.9 1.1 1 0 0 1 1 1 0 Transmembrane protein MFS_1 PF07690.11 KPI46053.1 - 5.6e-31 107.5 16.8 6.7e-31 107.2 11.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Zip PF02535.17 KPI46053.1 - 0.072 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SSF PF00474.12 KPI46054.1 - 4.2e-19 68.4 20.5 7.1e-19 67.7 14.2 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family zf-RING_2 PF13639.1 KPI46055.1 - 2.1e-06 27.4 4.0 2.1e-06 27.4 2.8 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KPI46055.1 - 7.9e-06 25.4 2.1 1.9e-05 24.2 1.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KPI46055.1 - 1.6e-05 24.5 3.6 3.8e-05 23.3 2.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KPI46055.1 - 2.6e-05 24.2 2.1 6.4e-05 22.9 1.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KPI46055.1 - 0.00029 20.4 4.2 0.00065 19.2 2.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KPI46055.1 - 0.00038 20.4 4.4 0.00085 19.3 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KPI46055.1 - 0.021 14.6 5.3 0.13 12.1 3.7 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KPI46055.1 - 0.33 11.0 8.1 0.93 9.5 5.6 1.8 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 KPI46055.1 - 0.5 10.0 9.2 0.4 10.4 4.3 2.3 2 0 0 2 2 2 0 PHD-finger zf-C3HC4_4 PF15227.1 KPI46055.1 - 0.92 9.4 3.4 0.53 10.2 0.7 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING AMP-binding PF00501.23 KPI46057.1 - 7e-67 225.6 0.0 9.5e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KPI46057.1 - 8e-11 42.7 0.1 1.6e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Amidohydro_2 PF04909.9 KPI46058.1 - 9.6e-33 113.8 0.0 1.3e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase DEAD PF00270.24 KPI46059.1 - 1e-31 109.6 0.1 1.9e-31 108.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KPI46059.1 - 2.2e-16 59.4 0.1 8.3e-16 57.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KPI46059.1 - 5.5e-05 22.1 0.0 8.7e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KPI46059.1 - 0.001 18.9 0.0 0.0024 17.7 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SopE_GEF PF07487.8 KPI46059.1 - 0.0023 17.9 0.0 0.31 10.9 0.0 2.3 2 0 0 2 2 2 1 SopE GEF domain Isochorismatase PF00857.15 KPI46060.1 - 7.4e-31 107.4 0.0 8.5e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family NAPRTase PF04095.11 KPI46061.1 - 1e-52 178.8 0.0 1.4e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family ThiF PF00899.16 KPI46062.1 - 4.4e-35 120.4 0.0 1.1e-34 119.2 0.0 1.7 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KPI46062.1 - 6.7e-17 60.8 0.6 2e-16 59.3 0.4 1.9 1 1 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 KPI46062.1 - 4.7e-07 30.1 0.0 9.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain ApbA PF02558.11 KPI46062.1 - 0.09 12.2 0.4 0.23 10.8 0.1 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Aa_trans PF01490.13 KPI46063.1 - 7.6e-82 274.9 30.8 8.8e-82 274.7 21.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Transglut_core PF01841.14 KPI46064.1 - 9.4e-16 58.0 1.5 2.1e-15 56.9 1.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.10 KPI46064.1 - 3.1e-15 55.8 2.0 5.6e-15 54.9 1.4 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Prefoldin_3 PF13758.1 KPI46066.1 - 6.4e-22 77.1 0.4 2.5e-21 75.3 0.1 2.2 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 KPI46066.1 - 6e-17 62.3 0.0 6e-17 62.3 0.0 4.9 5 1 0 5 5 5 1 Domain of unknown function (DUF3835) YL1 PF05764.8 KPI46066.1 - 0.00044 19.9 7.4 0.00044 19.9 5.2 2.7 2 1 1 3 3 3 1 YL1 nuclear protein GlutR_N PF05201.10 KPI46066.1 - 0.013 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain CCDC66 PF15236.1 KPI46066.1 - 0.28 10.8 0.0 0.28 10.8 0.0 3.0 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 66 ATP-grasp_2 PF08442.5 KPI46067.1 - 3e-61 206.3 0.0 4.4e-61 205.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KPI46067.1 - 3.2e-18 65.7 1.9 7.5e-18 64.5 1.3 1.7 1 1 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KPI46067.1 - 6.6e-13 48.3 0.0 1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KPI46067.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain PhyH PF05721.8 KPI46069.1 - 9.8e-24 84.5 0.0 1.9e-23 83.6 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KPI46069.1 - 0.025 13.0 0.0 0.033 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_2 PF13532.1 KPI46069.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Velvet PF11754.3 KPI46070.1 - 1.1e-58 198.2 0.0 1.6e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 Velvet factor MFS_1 PF07690.11 KPI46071.1 - 9.1e-30 103.5 27.7 1e-29 103.3 19.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PRA1 PF03208.14 KPI46072.1 - 1.3e-41 141.4 1.2 1.5e-41 141.3 0.8 1.0 1 0 0 1 1 1 1 PRA1 family protein Phage_holin_4 PF05105.7 KPI46072.1 - 0.04 13.6 0.9 0.11 12.1 0.0 2.0 1 1 0 2 2 2 0 Holin family SLAC1 PF03595.12 KPI46073.1 - 7.9e-81 271.2 54.6 9.1e-81 271.0 37.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DAD PF02109.11 KPI46073.1 - 6.5 6.8 10.2 0.29 11.1 1.5 2.5 2 0 0 2 2 2 0 DAD family DUF3671 PF12420.3 KPI46073.1 - 8.9 6.3 12.3 7.3 6.6 0.9 3.6 3 0 0 3 3 3 0 Protein of unknown function DAHP_synth_1 PF00793.15 KPI46074.1 - 1.6e-94 315.6 0.0 2.8e-94 314.8 0.0 1.3 1 0 0 1 1 1 1 DAHP synthetase I family Peptidase_M16_C PF05193.16 KPI46074.1 - 4.5e-24 85.1 0.0 6.3e-18 65.1 0.0 3.1 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KPI46074.1 - 0.0007 19.3 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Elongin_A PF06881.6 KPI46074.1 - 0.17 12.2 1.0 0.41 11.0 0.7 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A M16C_assoc PF08367.6 KPI46074.1 - 0.48 9.2 5.1 0.23 10.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase M16C associated bZIP_1 PF00170.16 KPI46075.1 - 0.0001 22.1 2.2 0.00034 20.5 1.6 1.9 1 0 0 1 1 1 1 bZIP transcription factor Zn_clus PF00172.13 KPI46075.1 - 0.015 15.1 8.8 0.049 13.5 6.1 1.9 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.10 KPI46075.1 - 0.1 12.4 5.6 1.1 9.1 3.9 2.6 1 1 0 1 1 1 0 Basic region leucine zipper zf-RING_2 PF13639.1 KPI46076.1 - 1.7e-08 34.1 4.3 3.8e-08 33.0 3.0 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 KPI46076.1 - 0.0003 20.6 5.4 0.0003 20.6 3.7 2.1 2 1 0 2 2 2 1 FANCL C-terminal domain zf-rbx1 PF12678.2 KPI46076.1 - 0.0015 18.5 3.1 0.0015 18.5 2.1 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger SWIM PF04434.12 KPI46076.1 - 0.0054 16.1 0.1 0.0096 15.3 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_4 PF14570.1 KPI46076.1 - 0.013 15.0 5.8 0.029 13.9 4.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KPI46076.1 - 0.013 15.2 2.3 0.013 15.2 1.6 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KPI46076.1 - 0.015 15.2 5.1 0.033 14.1 3.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KPI46076.1 - 0.04 13.5 4.8 0.14 11.8 3.3 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 KPI46076.1 - 0.05 13.2 6.7 0.11 12.2 4.6 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.1 KPI46076.1 - 0.13 11.9 4.7 0.49 10.1 3.4 1.9 1 1 1 2 2 2 0 zinc-RING finger domain C1_1 PF00130.17 KPI46076.1 - 0.85 9.3 6.9 0.9 9.3 1.5 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SCRL PF06876.7 KPI46076.1 - 2.1 8.3 7.3 0.61 10.0 0.9 2.3 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein Proteasome PF00227.21 KPI46077.1 - 9.2e-33 113.1 0.4 4.7e-32 110.8 0.3 1.9 1 1 0 1 1 1 1 Proteasome subunit Cylicin_N PF15241.1 KPI46078.1 - 0.23 11.3 1.5 0.8 9.6 0.2 2.0 1 1 1 2 2 2 0 Cylicin N-terminus Zn_clus PF00172.13 KPI46079.1 - 0.0014 18.4 2.9 0.0034 17.2 2.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HATPase_c PF02518.21 KPI46080.1 - 7e-21 74.0 0.0 1.3e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KPI46080.1 - 4.6e-15 55.6 0.2 9.1e-13 48.1 0.1 3.4 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KPI46080.1 - 8.5e-07 28.8 0.0 2.2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HSL_N PF06350.7 KPI46080.1 - 0.098 11.7 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus Apolipoprotein PF01442.13 KPI46080.1 - 0.14 11.6 0.2 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Tyrosinase PF00264.15 KPI46081.1 - 2.8e-19 70.1 1.8 4e-19 69.6 1.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Pro_isomerase PF00160.16 KPI46082.1 - 3.7e-48 163.6 0.0 7.4e-48 162.6 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KPI46082.1 - 3e-11 42.7 0.0 0.015 15.1 0.0 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat G_glu_transpept PF01019.16 KPI46083.1 - 3.4e-157 524.0 0.9 3.9e-157 523.8 0.7 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase WD40 PF00400.27 KPI46084.1 - 6.7e-16 57.4 7.5 4.6e-06 26.2 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Pro-kuma_activ PF09286.6 KPI46085.1 - 3.9e-42 143.6 0.1 6.3e-42 143.0 0.1 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KPI46085.1 - 1.6e-11 43.8 0.2 2.2e-10 40.1 0.0 2.2 2 0 0 2 2 2 1 Subtilase family Nucleo_P87 PF07267.6 KPI46086.1 - 0.2 10.3 2.6 0.41 9.2 1.8 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RRN3 PF05327.6 KPI46086.1 - 1 7.3 2.8 1.5 6.8 1.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1764 PF08576.5 KPI46086.1 - 1.1 10.1 6.7 4.6 8.0 4.6 2.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Glyco_hydro_20 PF00728.17 KPI46088.1 - 4.1e-82 276.1 0.2 4.9e-82 275.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DnaJ PF00226.26 KPI46089.1 - 7.8e-06 25.5 0.0 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain MFS_1 PF07690.11 KPI46090.1 - 1.4e-48 165.4 46.1 1e-47 162.5 32.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KPI46090.1 - 3.7e-14 51.8 16.6 5e-14 51.4 11.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CN_hydrolase PF00795.17 KPI46092.1 - 3.7e-21 75.3 0.0 7.9e-21 74.2 0.0 1.5 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase tRNA-synt_1 PF00133.17 KPI46093.1 - 2.3e-160 534.5 0.0 3e-160 534.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KPI46093.1 - 5.8e-23 81.3 0.2 1.1e-22 80.4 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KPI46093.1 - 2.4e-22 79.1 0.0 1.7e-12 46.7 0.0 3.5 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KPI46093.1 - 0.0067 15.5 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 KPI46093.1 - 0.18 11.0 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.9 KPI46093.1 - 0.47 10.1 3.7 0.99 9.1 0.3 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF3357 PF11837.3 KPI46094.1 - 0.14 12.0 0.3 0.61 9.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) S-methyl_trans PF02574.11 KPI46095.1 - 1.7e-34 119.5 0.0 2.6e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Aldo_ket_red PF00248.16 KPI46096.1 - 3.9e-50 170.2 0.0 4.6e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_75 PF07335.6 KPI46096.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 Glyco_hydro_11 PF00457.12 KPI46098.1 - 3.3e-75 251.4 22.3 3.9e-75 251.2 15.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Acetyltransf_1 PF00583.19 KPI46099.1 - 2.3e-13 49.9 0.0 3.6e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KPI46099.1 - 0.00096 19.2 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KPI46099.1 - 0.0092 16.1 0.0 0.012 15.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KPI46099.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 KPI46099.1 - 0.029 14.5 0.0 0.053 13.6 0.0 1.6 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain ABC_membrane PF00664.18 KPI46100.1 - 4.9e-46 157.3 30.9 2.5e-32 112.3 12.3 2.5 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 KPI46100.1 - 2.7e-45 154.0 0.0 7.6e-26 91.0 0.0 2.9 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KPI46100.1 - 7.9e-08 32.5 0.4 0.15 11.9 0.1 4.3 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.14 KPI46100.1 - 9.5e-08 31.5 3.8 0.0032 16.7 1.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KPI46100.1 - 1.6e-06 28.0 0.3 0.036 14.0 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KPI46100.1 - 5.9e-06 26.7 0.3 0.11 12.9 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KPI46100.1 - 1.2e-05 24.7 0.2 0.16 11.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KPI46100.1 - 4.3e-05 24.3 2.7 0.45 11.3 0.9 3.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KPI46100.1 - 6.1e-05 23.0 1.8 0.088 12.7 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain Zeta_toxin PF06414.7 KPI46100.1 - 0.00034 19.7 0.1 0.2 10.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_10 PF12846.2 KPI46100.1 - 0.00035 20.1 0.9 0.83 9.0 0.2 3.2 3 0 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 KPI46100.1 - 0.00038 20.6 0.6 1.2 9.2 0.1 3.6 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 KPI46100.1 - 0.0012 18.0 0.3 1.5 8.0 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ArgK PF03308.11 KPI46100.1 - 0.0019 17.0 1.9 0.48 9.1 0.2 2.4 2 0 0 2 2 2 2 ArgK protein AAA_25 PF13481.1 KPI46100.1 - 0.0052 16.1 0.0 0.97 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KPI46100.1 - 0.0055 17.0 1.5 1.2 9.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 KPI46100.1 - 0.0066 15.1 1.1 0.16 10.5 0.1 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_15 PF13175.1 KPI46100.1 - 0.0073 15.3 0.1 1.9 7.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 KPI46100.1 - 0.0087 15.7 0.8 0.9 9.2 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KPI46100.1 - 0.011 14.6 1.2 0.29 10.0 0.1 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein Dynamin_N PF00350.18 KPI46100.1 - 0.011 15.5 3.6 0.41 10.4 0.1 2.8 2 0 0 2 2 2 0 Dynamin family CbiA PF01656.18 KPI46100.1 - 0.035 13.5 0.3 1.6 8.1 0.0 3.0 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.12 KPI46100.1 - 0.041 13.4 1.5 3.6 7.0 0.3 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.1 KPI46100.1 - 0.047 13.2 4.9 1.8 8.0 0.5 2.8 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 KPI46100.1 - 0.056 13.1 0.4 0.48 10.0 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 KPI46100.1 - 0.074 13.0 2.8 0.2 11.6 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.1 KPI46100.1 - 0.088 13.1 10.7 0.52 10.6 0.1 3.2 4 0 0 4 4 3 0 AAA domain PduV-EutP PF10662.4 KPI46100.1 - 0.18 11.3 1.3 1.8 8.0 0.2 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 KPI46100.1 - 0.24 11.1 7.2 0.18 11.5 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF87 cobW PF02492.14 KPI46100.1 - 0.24 10.8 1.9 1.4 8.3 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 KPI46100.1 - 3.7 6.9 6.3 11 5.3 0.0 2.9 2 1 1 3 3 3 0 FtsK/SpoIIIE family FAD_binding_2 PF00890.19 KPI46101.1 - 1.1e-46 159.5 1.4 2.7e-46 158.2 1.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KPI46101.1 - 1.6e-13 50.2 0.1 1.1e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KPI46101.1 - 1.2e-09 37.1 0.0 0.0029 16.1 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.1 KPI46101.1 - 3.8e-06 27.1 0.0 8.9e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KPI46101.1 - 1.2e-05 24.4 0.0 5.9e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 KPI46101.1 - 4.5e-05 22.5 0.2 1.7 7.4 0.0 3.1 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KPI46101.1 - 0.00012 22.0 0.3 0.00097 19.0 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KPI46101.1 - 0.00032 19.4 0.9 0.019 13.6 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.1 KPI46101.1 - 0.0024 17.6 0.1 0.01 15.5 0.0 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.12 KPI46101.1 - 0.0036 16.4 0.0 0.0076 15.3 0.0 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KPI46101.1 - 0.021 14.8 0.0 0.079 13.0 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KPI46101.1 - 0.059 12.4 0.1 0.074 12.1 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KPI46101.1 - 0.16 12.4 0.2 17 5.9 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KPI46101.1 - 0.23 10.3 0.0 1.6 7.5 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Methyltransf_28 PF02636.12 KPI46102.1 - 0.064 12.6 0.1 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ribonuc_2-5A PF06479.7 KPI46102.1 - 0.11 12.3 0.6 0.26 11.1 0.2 1.7 1 1 1 2 2 2 0 Ribonuclease 2-5A Cytochrome_C7 PF14522.1 KPI46102.1 - 2.2 7.9 6.3 5.3 6.7 4.4 1.7 1 1 0 1 1 1 0 Cytochrome c7 FAD-oxidase_C PF02913.14 KPI46104.1 - 1.4e-16 60.6 0.0 1.9e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain APG5 PF04106.7 KPI46105.1 - 9.2e-51 172.1 0.0 1.1e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 MFS_1 PF07690.11 KPI46106.1 - 3.2e-39 134.6 82.0 1.6e-32 112.5 35.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3753 PF12575.3 KPI46106.1 - 2.8 7.7 5.7 22 4.9 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) NMO PF03060.10 KPI46108.1 - 6.2e-68 229.3 3.3 7.9e-68 229.0 2.3 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KPI46108.1 - 1.7e-05 23.9 0.1 0.00015 20.8 0.1 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KPI46108.1 - 0.06 12.1 2.8 0.11 11.3 1.9 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Radial_spoke_3 PF06098.6 KPI46108.1 - 0.21 10.5 0.1 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 PEP-utilizers PF00391.18 KPI46108.1 - 0.3 10.6 4.5 0.16 11.5 0.3 2.5 3 0 0 3 3 3 0 PEP-utilising enzyme, mobile domain DNA_pol_E_B PF04042.11 KPI46109.1 - 2.7e-45 154.2 0.0 3.5e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PepX_C PF08530.5 KPI46110.1 - 4.9e-24 85.4 0.7 1.1e-23 84.2 0.3 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 KPI46110.1 - 4.5e-18 65.6 0.1 1.1e-09 38.1 0.0 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 KPI46110.1 - 0.012 15.4 0.1 0.12 12.1 0.1 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family