# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- FAD_binding_4 PF01565.23 EON95592.1 - 8.8e-23 80.6 6.1 2.4e-22 79.2 6.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EON95592.1 - 4.2e-09 36.4 0.0 1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Lipase_2 PF01674.18 EON95592.1 - 0.14 11.6 0.1 0.7 9.4 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 2) DUF3292 PF11696.8 EON95593.1 - 1.1e-66 225.7 0.6 5.7e-66 223.3 0.6 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) GRAM PF02893.20 EON95593.1 - 0.0092 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 GRAM domain PH_TFIIH PF08567.11 EON95593.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain SNF2_N PF00176.23 EON95594.1 - 4.9e-47 160.3 0.0 9.4e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 EON95594.1 - 1.2e-27 95.8 4.6 1.2e-27 95.8 4.6 2.2 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 EON95594.1 - 6.5e-20 71.5 0.0 1.1e-18 67.6 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EON95594.1 - 7.9e-07 28.5 0.6 2.2e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EON95594.1 - 2.4e-06 27.6 0.0 2.5e-05 24.4 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EON95594.1 - 8.2e-05 22.4 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SEC-C PF02810.15 EON95594.1 - 3.1 7.8 9.7 6.9 6.7 9.7 1.6 1 0 0 1 1 1 0 SEC-C motif Glyco_transf_28 PF03033.20 EON95595.1 - 3.6e-08 33.5 0.0 1.2e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain p450 PF00067.22 EON95597.1 - 3.5e-48 164.5 0.0 1.6e-47 162.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 G-alpha PF00503.20 EON95598.1 - 4.1e-110 368.3 0.3 4.8e-110 368.1 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EON95598.1 - 1.3e-13 50.8 0.9 2e-08 33.9 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EON95598.1 - 0.00013 21.4 1.2 0.01 15.2 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 EON95598.1 - 0.0031 16.9 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Roc PF08477.13 EON95598.1 - 0.024 14.9 0.2 6.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 EON95598.1 - 0.042 13.4 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EON95598.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MF_alpha_N PF05436.11 EON95599.1 - 0.19 11.6 0.4 0.34 10.8 0.3 1.5 1 1 0 1 1 1 0 Mating factor alpha precursor N-terminus CN_hydrolase PF00795.22 EON95600.1 - 7.4e-58 195.9 0.0 8.4e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LCM PF04072.14 EON95600.1 - 0.047 13.6 0.0 7.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Leucine carboxyl methyltransferase CMAS PF02353.20 EON95601.1 - 2.3e-18 66.5 0.0 6.7e-16 58.4 0.0 2.1 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EON95601.1 - 1.1e-16 61.2 0.1 2.6e-16 60.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON95601.1 - 1.3e-14 54.6 0.4 3.6e-13 50.0 0.4 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON95601.1 - 1.5e-13 50.9 0.0 2.3e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON95601.1 - 2.9e-13 49.9 0.4 1.4e-11 44.4 0.4 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON95601.1 - 3.9e-13 50.0 0.0 8.4e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EON95601.1 - 0.00018 21.1 0.1 0.0057 16.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.12 EON95601.1 - 0.00028 20.6 0.2 0.0016 18.1 0.2 2.0 1 1 1 2 2 2 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 EON95601.1 - 0.0012 18.3 0.1 0.0089 15.4 0.1 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EON95601.1 - 0.0015 18.4 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 EON95601.1 - 0.0036 16.7 0.0 0.007 15.8 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 EON95601.1 - 0.0077 16.2 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EON95601.1 - 0.0091 15.5 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 FtsJ PF01728.19 EON95601.1 - 0.024 14.8 0.0 0.041 14.0 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_PK PF05891.12 EON95601.1 - 0.035 13.6 0.2 0.11 12.0 0.2 1.7 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase ADH_zinc_N PF00107.26 EON95601.1 - 0.047 13.7 0.1 0.32 11.0 0.1 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Peptidase_M1 PF01433.20 EON95602.1 - 1.2e-43 149.2 0.2 1.8e-43 148.6 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EON95602.1 - 3.2e-38 130.3 0.0 5.6e-38 129.5 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EON95602.1 - 2.3e-28 99.7 0.2 4.2e-28 98.8 0.2 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 EON95602.1 - 0.015 15.0 0.2 0.59 9.8 0.2 3.1 3 1 0 3 3 3 0 Peptidase MA superfamily Glyco_hydro_3_C PF01915.22 EON95603.1 - 4.2e-39 134.6 0.0 1.4e-38 132.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EON95603.1 - 9.3e-38 130.4 0.0 1.4e-37 129.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EON95603.1 - 2.2e-22 78.9 0.1 3.8e-22 78.2 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Kinesin PF00225.23 EON95604.1 - 8.1e-108 360.3 1.7 1.4e-107 359.5 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 EON95604.1 - 1.1e-35 123.4 19.3 9.6e-31 107.3 0.2 3.8 3 1 1 4 4 4 2 Kinesin-associated Microtub_bd PF16796.5 EON95604.1 - 4.2e-23 81.9 0.0 1.4e-22 80.3 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 EON95604.1 - 2.6e-07 31.0 0.2 1.2e-06 28.9 0.2 2.3 1 0 0 1 1 1 1 Kinesin protein 1B DUF3694 PF12473.8 EON95604.1 - 6.4e-07 30.2 0.5 6e-06 27.0 0.0 2.7 2 1 0 2 2 2 1 Kinesin protein FHA PF00498.26 EON95604.1 - 0.0001 22.6 0.0 0.0019 18.5 0.0 3.0 3 0 0 3 3 3 1 FHA domain PH PF00169.29 EON95604.1 - 0.018 15.5 0.0 6.5 7.3 0.0 2.8 2 0 0 2 2 2 0 PH domain Yop-YscD_cpl PF16697.5 EON95604.1 - 0.02 15.2 0.0 0.19 12.1 0.0 2.4 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain V_ATPase_I PF01496.19 EON95604.1 - 2.9 5.7 10.1 4.3 5.1 6.1 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4065 PF13274.6 EON95604.1 - 8.1 7.4 6.5 11 6.9 2.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) Uds1 PF15456.6 EON95605.1 - 1.8e-32 112.3 7.7 5.2e-32 110.7 7.7 1.9 1 0 0 1 1 1 1 Up-regulated During Septation Stathmin PF00836.19 EON95605.1 - 2.6 8.0 6.0 0.38 10.7 0.5 2.4 2 0 0 2 2 2 0 Stathmin family Spermine_synth PF01564.17 EON95606.1 - 2.2e-74 249.0 0.0 3.5e-74 248.3 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EON95606.1 - 1.7e-22 79.1 0.1 2.8e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EON95606.1 - 3.6e-05 24.4 0.0 6.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON95606.1 - 0.0011 19.7 0.2 0.0076 17.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.16 EON95606.1 - 0.0076 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_24 PF13578.6 EON95606.1 - 0.079 14.0 0.0 0.17 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EON95606.1 - 0.082 12.2 0.1 0.16 11.3 0.1 1.6 1 1 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 EON95606.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain ECH_1 PF00378.20 EON95607.1 - 1.2e-39 136.2 0.4 2.3e-31 109.0 0.0 3.2 3 0 0 3 3 3 3 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON95607.1 - 1.8e-24 86.9 0.2 3.5e-21 76.1 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase FAD_binding_4 PF01565.23 EON95608.1 - 2.2e-19 69.6 0.9 4.1e-19 68.7 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EON95608.1 - 9.9e-10 38.4 1.0 2.4e-09 37.2 1.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF1989 PF09347.10 EON95609.1 - 1.9e-39 135.0 0.0 2.3e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) HET PF06985.11 EON95610.1 - 2.8e-29 102.3 0.2 4.3e-29 101.7 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Beta-lactamase PF00144.24 EON95611.1 - 5.1e-40 137.7 0.1 7e-40 137.3 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase adh_short PF00106.25 EON95612.1 - 4.4e-24 85.0 0.0 3.2e-19 69.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON95612.1 - 1.4e-10 41.2 0.0 1e-08 35.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON95612.1 - 0.00011 22.1 0.2 0.00021 21.2 0.2 1.3 1 0 0 1 1 1 1 KR domain LamB_YcsF PF03746.16 EON95613.1 - 7.6e-76 254.9 0.0 9.3e-76 254.6 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family RGS PF00615.19 EON95614.1 - 1.7e-05 25.0 0.0 0.0015 18.8 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain ADH_zinc_N PF00107.26 EON95616.1 - 7.4e-08 32.4 0.0 1.4e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON95616.1 - 6e-05 22.9 0.1 9.5e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fungal_trans_2 PF11951.8 EON95617.1 - 7.8e-06 24.9 0.0 8.8e-06 24.8 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.21 EON95618.1 - 7.8e-78 262.2 34.2 9.2e-78 261.9 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON95618.1 - 4.5e-26 91.7 35.7 5.5e-26 91.4 35.7 1.1 1 0 0 1 1 1 1 Amino acid permease FMO-like PF00743.19 EON95619.1 - 4.4e-10 38.6 0.0 3e-09 35.8 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EON95619.1 - 1e-07 32.1 0.0 2.4e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EON95619.1 - 0.0013 18.0 0.0 0.58 9.3 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EON95619.1 - 0.0016 18.4 0.1 0.077 13.0 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EON95619.1 - 0.0084 15.4 0.0 0.59 9.3 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EON95619.1 - 0.01 15.1 0.0 0.13 11.5 0.0 2.3 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.6 EON95619.1 - 0.015 14.5 0.0 1.1 8.4 0.0 3.0 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) IlvN PF07991.12 EON95619.1 - 0.05 13.2 0.6 0.25 10.9 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 EON95619.1 - 0.15 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 EON95619.1 - 0.18 10.5 0.7 5.4 5.6 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein Acetyltransf_8 PF13523.6 EON95620.1 - 3.8e-35 120.7 0.2 5.7e-35 120.1 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SGL PF08450.12 EON95621.1 - 0.00019 21.1 0.1 0.08 12.5 0.1 2.5 3 0 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Sugar_tr PF00083.24 EON95622.1 - 4.6e-20 71.9 16.5 7.3e-10 38.3 8.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EON95622.1 - 1e-07 31.2 17.6 1.6e-06 27.3 17.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3792 PF12670.7 EON95622.1 - 0.01 16.0 5.3 0.01 16.0 5.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) PrgI PF12666.7 EON95622.1 - 0.046 14.4 0.1 0.046 14.4 0.1 2.4 1 1 1 2 2 2 0 PrgI family protein PEN-2 PF10251.9 EON95622.1 - 0.11 12.9 4.9 4.7 7.7 0.8 2.6 2 1 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase Wzy_C PF04932.15 EON95622.1 - 9.4 5.8 14.0 0.6 9.7 3.5 2.1 1 1 1 2 2 2 0 O-Antigen ligase Aldose_epim PF01263.20 EON95623.1 - 1.4e-34 119.8 0.1 2e-34 119.3 0.1 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Sugar_tr PF00083.24 EON95624.1 - 7.1e-78 262.5 21.2 8.2e-78 262.3 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON95624.1 - 2.7e-19 69.3 28.9 2.7e-19 69.3 28.9 2.1 2 1 1 3 3 3 2 Major Facilitator Superfamily SRPRB PF09439.10 EON95624.1 - 0.096 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1741 PF08427.10 EON95625.1 - 2.6e-90 302.1 0.9 5.5e-90 301.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Orai-1 PF07856.12 EON95626.1 - 0.00095 18.9 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Mediator of CRAC channel activity CHCH PF06747.13 EON95626.1 - 0.62 10.3 3.8 7.1 6.9 0.3 2.5 2 0 0 2 2 2 0 CHCH domain Cmc1 PF08583.10 EON95626.1 - 1.7 8.7 12.0 0.98 9.5 3.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like FAP PF07174.11 EON95627.1 - 0.029 13.9 1.2 0.041 13.3 1.2 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Protamine_like PF06382.11 EON95627.1 - 0.16 12.2 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 Protamine and protamine like Sulfate_transp PF00916.20 EON95628.1 - 5.8e-77 259.0 9.9 7.9e-77 258.5 9.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EON95628.1 - 1.6e-08 34.2 0.0 2.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EON95628.1 - 0.031 14.6 1.1 0.064 13.6 0.1 2.1 2 0 0 2 2 2 0 STAS domain DUF1700 PF08006.11 EON95628.1 - 2.2 7.8 8.4 0.5 9.9 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) MFS_1 PF07690.16 EON95629.1 - 4.7e-30 104.7 56.7 3.3e-22 78.9 19.0 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON95629.1 - 4.8e-09 35.6 7.8 4.8e-09 35.6 7.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Ysc84 PF04366.12 EON95630.1 - 3.2e-47 159.5 0.1 5.1e-47 158.8 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator UNC-93 PF05978.16 EON95631.1 - 1.5e-12 47.5 2.3 5.5e-12 45.7 2.3 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EON95631.1 - 6.6e-12 45.0 35.6 6.6e-12 45.0 35.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EON95631.1 - 0.042 12.7 6.8 0.041 12.7 3.1 2.5 1 1 0 2 2 2 0 MFS_1 like family DUF1304 PF06993.12 EON95631.1 - 8 6.5 12.7 0.059 13.4 2.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1304) MgsA_C PF12002.8 EON95632.1 - 7.7e-59 198.4 0.0 1.3e-58 197.7 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EON95632.1 - 4.8e-24 84.5 0.1 9.8e-24 83.5 0.1 1.5 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EON95632.1 - 7.2e-14 52.3 0.1 1.6e-13 51.2 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EON95632.1 - 9.6e-09 35.2 0.0 1.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 EON95632.1 - 7.7e-06 25.7 0.1 0.00022 21.0 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 EON95632.1 - 1.3e-05 25.7 1.3 0.015 15.7 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 EON95632.1 - 2e-05 24.1 0.2 0.032 13.6 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EON95632.1 - 4.2e-05 23.6 0.0 0.00039 20.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EON95632.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EON95632.1 - 0.0014 18.9 0.5 0.0096 16.2 0.4 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EON95632.1 - 0.0048 16.1 0.0 0.008 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 EON95632.1 - 0.006 16.9 0.2 0.097 13.0 0.2 2.3 1 1 1 2 2 2 1 AAA domain ResIII PF04851.15 EON95632.1 - 0.009 16.0 0.5 0.37 10.8 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit TIP49 PF06068.13 EON95632.1 - 0.0097 15.1 0.1 0.024 13.8 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 EON95632.1 - 0.019 14.8 0.0 0.062 13.2 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNF220 PF15926.5 EON95632.1 - 0.026 14.2 0.5 0.21 11.2 0.2 2.0 1 1 1 2 2 2 0 E3 ubiquitin-protein ligase RNF220 Sigma54_activ_2 PF14532.6 EON95632.1 - 0.037 14.2 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain SKI PF01202.22 EON95632.1 - 0.039 14.1 0.1 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 Shikimate kinase CPT PF07931.12 EON95632.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.6 EON95632.1 - 0.068 12.9 0.6 0.26 11.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_2 PF07724.14 EON95632.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 EON95632.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EON95632.1 - 0.095 12.5 0.1 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EON95632.1 - 0.11 13.0 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EON95632.1 - 0.12 12.9 0.1 0.54 10.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter TniB PF05621.11 EON95632.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_28 PF13521.6 EON95632.1 - 0.3 11.3 1.4 1.2 9.4 1.4 2.0 1 1 0 1 1 1 0 AAA domain adh_short PF00106.25 EON95634.1 - 7.8e-23 80.9 0.1 1.6e-16 60.4 0.0 2.3 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON95634.1 - 1.9e-17 63.6 0.2 2.6e-16 59.9 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON95634.1 - 0.031 14.2 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 KR domain MFS_1 PF07690.16 EON95635.1 - 7.1e-37 127.1 33.4 1.1e-36 126.5 31.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EON95635.1 - 0.0016 17.4 12.5 0.0033 16.3 12.5 1.6 1 0 0 1 1 1 1 MFS_1 like family ESSS PF10183.9 EON95635.1 - 0.07 13.3 0.1 2.3 8.5 0.0 2.6 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2070 PF09843.9 EON95635.1 - 6.3 5.0 16.3 0.3 9.3 5.7 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Methyltransf_23 PF13489.6 EON95636.1 - 1.2e-05 25.2 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AIG1 PF04548.16 EON95637.1 - 0.022 14.1 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 AIG1 family Mito_fiss_reg PF05308.11 EON95637.1 - 1.5 8.9 6.5 1.1 9.3 3.9 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator LRR_9 PF14580.6 EON95638.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat MFS_1 PF07690.16 EON95639.1 - 5.4e-24 84.8 46.2 5.4e-24 84.8 46.2 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EON95639.1 - 7.3e-12 44.5 14.4 1.5e-11 43.4 14.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HpcH_HpaI PF03328.14 EON95640.1 - 4.2e-34 117.6 0.0 5.5e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF4267 PF14087.6 EON95641.1 - 1e-26 93.2 3.8 1.2e-26 92.9 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) KR PF08659.10 EON95642.1 - 2e-39 135.4 0.0 5.2e-39 134.0 0.0 1.8 2 0 0 2 2 2 1 KR domain Methyltransf_12 PF08242.12 EON95642.1 - 1e-19 71.1 0.0 3e-19 69.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON95642.1 - 6.5e-15 55.4 0.0 1.4e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON95642.1 - 9.5e-14 51.9 0.0 1.8e-12 47.8 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON95642.1 - 2.6e-11 43.5 0.0 5.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON95642.1 - 9.2e-11 42.3 0.0 2.5e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EON95642.1 - 4.5e-09 36.1 0.0 1.7e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 EON95642.1 - 6e-09 36.1 0.2 2.2e-08 34.3 0.1 2.2 2 0 0 2 2 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 EON95642.1 - 1.3e-06 27.9 0.0 2.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EON95642.1 - 0.00035 20.2 0.0 0.0008 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EON95642.1 - 0.002 17.8 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_33 PF10017.9 EON95642.1 - 0.0025 17.0 0.0 0.0045 16.2 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent RrnaAD PF00398.20 EON95642.1 - 0.012 14.7 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 EON95642.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EON95642.1 - 0.077 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase NNMT_PNMT_TEMT PF01234.17 EON95642.1 - 0.17 11.1 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Glyco_hydro_114 PF03537.13 EON95643.1 - 4.2e-80 268.4 0.1 4.7e-80 268.2 0.1 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 AA_permease PF00324.21 EON95644.1 - 8.9e-114 380.7 45.3 1.1e-113 380.4 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON95644.1 - 1.3e-28 100.0 50.1 1.8e-28 99.5 50.0 1.3 1 1 0 1 1 1 1 Amino acid permease TNFR_16_TM PF18422.1 EON95644.1 - 0.11 12.4 1.1 0.31 11.0 1.1 1.7 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Sod_Fe_C PF02777.18 EON95645.1 - 2.5e-37 127.1 0.1 3.7e-37 126.6 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EON95645.1 - 3.6e-31 107.5 0.2 6.2e-31 106.7 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF5042 PF16445.5 EON95645.1 - 0.029 12.8 0.0 0.039 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5042) ABC_tran PF00005.27 EON95646.1 - 6.2e-07 30.0 0.0 1.1e-06 29.2 0.0 1.5 2 0 0 2 2 2 1 ABC transporter Aldedh PF00171.22 EON95647.1 - 5.3e-93 312.0 0.8 5.9e-93 311.9 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EON95647.1 - 8.7e-05 22.1 0.0 0.016 14.7 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Gelsolin PF00626.22 EON95649.1 - 4.4e-36 122.6 0.1 1.6e-12 47.2 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat ADH_zinc_N PF00107.26 EON95650.1 - 4.9e-21 75.1 0.0 7.2e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON95650.1 - 1.4e-15 58.5 0.0 2.4e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON95650.1 - 5.1e-08 32.8 0.0 2.3e-07 30.7 0.0 2.1 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 EON95651.1 - 6.5e-15 55.3 0.1 7.3e-14 51.8 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EON95651.1 - 2.4e-08 34.1 0.1 3.8e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EON95651.1 - 2.7e-08 33.6 0.0 1.6e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EON95651.1 - 2.8e-08 33.2 0.0 1.8e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EON95651.1 - 2.7e-07 29.9 0.0 4.1e-07 29.3 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EON95651.1 - 8.3e-07 28.8 0.0 1.8e-06 27.7 0.1 1.5 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EON95651.1 - 1.9e-05 24.2 0.4 0.1 12.0 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON95651.1 - 0.047 13.2 0.3 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON95651.1 - 0.11 12.4 0.4 0.43 10.5 0.4 1.9 1 1 0 1 1 1 0 KR domain DUF1456 PF07308.13 EON95651.1 - 0.12 12.7 0.0 6.6 7.1 0.0 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1456) Amidohydro_2 PF04909.14 EON95652.1 - 1.9e-37 129.6 0.4 2.6e-37 129.2 0.4 1.3 1 0 0 1 1 1 1 Amidohydrolase FcoT PF10862.8 EON95652.1 - 0.15 11.6 0.3 2 8.0 0.2 2.3 1 1 1 2 2 2 0 FcoT-like thioesterase domain AcetylCoA_hydro PF02550.15 EON95653.1 - 2.9e-47 161.2 0.0 4.7e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 EON95653.1 - 5.9e-40 136.7 0.0 8.6e-40 136.2 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Cellulase PF00150.18 EON95654.1 - 2.6e-32 112.4 0.0 3.7e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_6 PF12697.7 EON95655.1 - 1.1e-06 29.5 1.3 1.3e-06 29.2 1.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON95655.1 - 1.4e-06 28.2 0.5 2.4e-06 27.4 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON95655.1 - 6.7e-06 25.5 0.1 1.1e-05 24.8 0.1 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Fungal_lectin PF07938.12 EON95656.1 - 2.6e-06 27.0 0.5 0.01 15.3 0.2 2.6 1 1 1 2 2 2 2 Fungal fucose-specific lectin Lipase_GDSL_2 PF13472.6 EON95657.1 - 0.00046 20.6 0.0 0.00061 20.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Aminotran_3 PF00202.21 EON95658.1 - 3.5e-46 157.7 0.2 1.1e-44 152.8 0.2 2.2 1 1 0 1 1 1 1 Aminotransferase class-III Epimerase PF01370.21 EON95660.1 - 0.00012 21.6 0.0 0.00023 20.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EON95660.1 - 0.11 11.7 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein NmrA PF05368.13 EON95661.1 - 1.3e-31 110.0 0.0 1.6e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EON95661.1 - 1.3e-18 67.5 0.0 2e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EON95661.1 - 3.7e-06 26.6 0.0 1.4e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EON95661.1 - 0.00054 19.5 0.0 0.0017 17.9 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EON95661.1 - 0.053 12.9 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 EON95661.1 - 0.086 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.19 EON95661.1 - 0.13 11.3 0.0 0.31 10.0 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glycos_transf_1 PF00534.20 EON95662.1 - 1.1e-24 86.9 0.0 2.1e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EON95662.1 - 9.3e-15 55.2 0.0 1.5e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EON95662.1 - 0.0017 18.7 0.0 0.0056 17.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cellulase PF00150.18 EON95663.1 - 1.9e-28 99.7 0.5 2.8e-28 99.2 0.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Alpha-amylase PF00128.24 EON95664.1 - 2e-99 333.4 0.2 2.6e-99 333.0 0.2 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain adh_short PF00106.25 EON95665.1 - 1.5e-39 135.5 0.0 2.4e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON95665.1 - 6.7e-22 78.2 0.0 9.3e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON95665.1 - 1.2e-06 28.5 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EON95665.1 - 0.00052 20.5 0.3 0.0013 19.3 0.3 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 EON95665.1 - 0.00075 19.0 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EON95665.1 - 0.002 17.3 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EON95665.1 - 0.0029 17.1 0.2 0.0042 16.5 0.2 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EON95665.1 - 0.0033 17.5 0.0 0.0055 16.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EON95665.1 - 0.012 15.9 0.1 0.026 14.8 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 EON95665.1 - 0.015 15.2 0.5 0.059 13.3 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.24 EON95666.1 - 6e-92 308.9 18.4 7e-92 308.6 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON95666.1 - 7.9e-30 104.0 22.0 2.5e-28 99.0 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EON95666.1 - 0.00017 20.2 4.2 0.00017 20.2 4.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EON95666.1 - 0.0073 14.7 8.5 0.026 12.8 2.1 2.6 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family PTR2 PF00854.21 EON95666.1 - 4.3 6.1 15.6 1.9 7.2 2.0 3.2 2 1 1 3 3 3 0 POT family Neurensin PF14927.6 EON95666.1 - 6 6.6 6.8 2.6 7.8 1.0 2.8 3 0 0 3 3 3 0 Neurensin Sugar_tr PF00083.24 EON95667.1 - 1.8e-13 50.2 18.0 2.1e-13 50.0 18.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON95667.1 - 4.4e-06 25.9 9.0 5.7e-06 25.5 9.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1761 PF08570.10 EON95667.1 - 3.7 7.8 12.8 0.46 10.8 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) Pec_lyase_C PF00544.19 EON95669.1 - 4e-39 134.4 4.3 5.2e-39 134.0 4.3 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EON95669.1 - 0.0033 17.3 5.8 0.15 11.9 5.7 2.3 1 1 0 1 1 1 1 Right handed beta helix region AA_permease PF00324.21 EON95671.1 - 3.9e-149 497.3 34.3 4.5e-149 497.1 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON95671.1 - 4.8e-39 134.4 39.5 6.9e-39 133.9 39.5 1.2 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.25 EON95672.1 - 7.8e-23 80.9 0.3 1e-17 64.3 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON95672.1 - 5.2e-14 52.4 0.3 4e-10 39.6 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON95672.1 - 7e-05 22.8 0.1 0.00011 22.1 0.1 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EON95672.1 - 0.046 14.3 0.0 13 6.5 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SDF PF00375.18 EON95673.1 - 1.1e-72 245.3 17.6 1.2e-72 245.1 17.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Kei1 PF08552.11 EON95673.1 - 0.039 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 adh_short PF00106.25 EON95674.1 - 3.9e-20 72.1 0.7 1.8e-18 66.7 0.6 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EON95674.1 - 7.4e-11 42.3 0.4 9.8e-11 41.9 0.4 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EON95674.1 - 4.2e-10 39.6 2.7 4.8e-10 39.4 1.4 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 EON95674.1 - 0.01 15.0 0.5 0.56 9.3 0.5 2.1 1 1 0 1 1 1 0 Male sterility protein PIN PF01850.21 EON95674.1 - 0.06 13.8 0.2 0.14 12.7 0.1 1.6 2 0 0 2 2 2 0 PIN domain Activator-TraM PF11657.8 EON95674.1 - 0.1 12.4 0.8 0.18 11.7 0.3 1.6 1 1 1 2 2 2 0 Transcriptional activator TraM DSPc PF00782.20 EON95675.1 - 1.6e-12 47.4 0.0 8.5e-05 22.4 0.0 3.2 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EON95675.1 - 0.0026 18.0 0.0 0.03 14.6 0.0 2.1 2 0 0 2 2 2 1 Rit1 DUSP-like domain adh_short PF00106.25 EON95676.1 - 3.3e-19 69.1 0.2 3.6e-19 69.0 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON95676.1 - 9.3e-12 45.0 0.1 1e-11 44.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON95676.1 - 1.2e-07 31.8 0.1 1.3e-07 31.7 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON95676.1 - 3.7e-05 23.3 0.2 5.1e-05 22.9 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EON95676.1 - 8.6e-05 22.5 0.1 0.00011 22.2 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Hydrolase PF00702.26 EON95676.1 - 0.0021 18.4 0.2 0.0037 17.6 0.2 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase SH3_9 PF14604.6 EON95677.1 - 3e-07 30.2 0.0 5.8e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EON95677.1 - 1.7e-05 24.4 0.0 3.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EON95677.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Sugar_tr PF00083.24 EON95678.1 - 1.4e-89 301.1 22.9 1.6e-89 300.9 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON95678.1 - 7.2e-26 90.9 36.1 3.5e-22 78.8 11.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EON95678.1 - 1.7e-09 36.7 1.0 1.7e-09 36.7 1.0 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) HET PF06985.11 EON95679.1 - 0.16 12.3 0.1 0.16 12.3 0.1 2.4 3 1 0 3 3 3 0 Heterokaryon incompatibility protein (HET) Med18 PF09637.10 EON95680.1 - 1.4e-28 100.4 0.0 1.7e-28 100.2 0.0 1.0 1 0 0 1 1 1 1 Med18 protein Vfa1 PF08432.10 EON95681.1 - 1.4e-29 103.7 22.7 1.6e-29 103.5 22.7 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Rtf2 PF04641.12 EON95681.1 - 0.0038 16.6 16.7 0.0041 16.5 16.7 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger DUF4746 PF15928.5 EON95681.1 - 0.017 14.5 15.0 0.018 14.5 15.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PPL5 PF18168.1 EON95681.1 - 0.026 13.8 12.6 0.029 13.7 12.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 XRN_M PF17846.1 EON95681.1 - 0.048 12.6 8.8 0.056 12.4 8.8 1.0 1 0 0 1 1 1 0 Xrn1 helical domain RR_TM4-6 PF06459.12 EON95681.1 - 0.088 12.6 19.2 0.1 12.4 19.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 EON95681.1 - 0.093 12.9 4.8 0.097 12.8 4.8 1.1 1 0 0 1 1 1 0 DDHD domain NPR3 PF03666.13 EON95681.1 - 0.13 11.0 16.3 0.15 10.8 16.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAPS PF04499.15 EON95681.1 - 0.32 9.7 14.2 0.34 9.6 14.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SID-1_RNA_chan PF13965.6 EON95681.1 - 0.36 9.2 2.3 0.38 9.1 2.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SLC12 PF03522.15 EON95681.1 - 0.48 9.4 13.2 0.53 9.2 13.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 NOA36 PF06524.12 EON95681.1 - 0.5 9.6 18.7 0.61 9.4 18.7 1.2 1 0 0 1 1 1 0 NOA36 protein MAJIN PF15077.6 EON95681.1 - 0.62 9.8 10.8 0.73 9.6 10.8 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF5308 PF17233.2 EON95681.1 - 0.99 9.6 5.2 1.6 9.0 5.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Presenilin PF01080.17 EON95681.1 - 1.4 7.6 16.0 1.7 7.3 16.0 1.0 1 0 0 1 1 1 0 Presenilin DUF1168 PF06658.12 EON95681.1 - 2.1 8.1 37.9 2.7 7.8 37.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF908 PF06012.12 EON95681.1 - 2.2 7.6 8.3 2.5 7.5 8.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SpoIIP PF07454.11 EON95681.1 - 2.4 7.6 18.3 3.2 7.2 18.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) VIR_N PF15912.5 EON95681.1 - 2.8 7.5 13.8 3 7.4 13.8 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal GCD14 PF08704.10 EON95681.1 - 5 6.7 9.4 6.3 6.4 9.4 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF2722 PF10846.8 EON95681.1 - 6 5.7 17.4 6.8 5.5 17.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2076 PF09849.9 EON95681.1 - 6.5 6.7 14.3 8.1 6.4 14.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF5427 PF10310.9 EON95681.1 - 7.3 5.4 21.1 8.6 5.2 21.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Membralin PF09746.9 EON95681.1 - 7.7 5.4 6.4 8.5 5.3 6.4 1.1 1 0 0 1 1 1 0 Tumour-associated protein Zip PF02535.22 EON95681.1 - 8.2 5.5 12.5 9.7 5.3 12.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 EON95681.1 - 9 6.2 17.7 11 5.9 17.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A U79_P34 PF03064.16 EON95681.1 - 9.2 5.6 27.3 11 5.3 27.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Serinc PF03348.15 EON95681.1 - 9.3 5.1 7.4 10 4.9 7.4 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) MCM_bind PF09739.9 EON95681.1 - 9.5 4.5 16.6 11 4.3 16.6 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NmrA PF05368.13 EON95682.1 - 2.5e-24 86.1 0.0 6e-24 84.9 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EON95682.1 - 2.3e-11 43.9 0.0 8e-11 42.2 0.0 1.9 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EON95682.1 - 0.0044 16.5 0.0 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EON95682.1 - 0.08 13.4 0.0 0.16 12.4 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain LigB PF02900.18 EON95683.1 - 2.9e-32 111.8 0.0 4e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PNK3P PF08645.11 EON95684.1 - 6.9e-56 188.4 0.0 1.2e-55 187.6 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EON95684.1 - 4e-27 95.1 0.0 8.8e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EON95684.1 - 0.0024 17.4 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 TsaE PF02367.17 EON95684.1 - 0.032 14.2 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EON95684.1 - 0.035 13.4 0.0 0.087 12.1 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 EON95684.1 - 0.093 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 EON95684.1 - 0.17 12.2 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.12 EON95685.1 - 8.2e-05 22.7 0.7 0.25 11.4 0.0 3.0 1 1 2 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus Sugar_tr PF00083.24 EON95686.1 - 6.2e-27 94.6 15.4 7e-27 94.4 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON95686.1 - 2.4e-09 36.6 10.5 2.8e-09 36.4 10.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Pex14_N PF04695.13 EON95686.1 - 0.011 16.5 0.2 0.017 15.8 0.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FA_desaturase PF00487.24 EON95686.1 - 0.071 12.9 2.1 0.1 12.4 2.1 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DUF1673 PF07895.11 EON95686.1 - 0.23 11.2 3.0 0.36 10.5 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) S36_mt PF10937.8 EON95687.1 - 1.1e-42 146.3 2.2 1.4e-42 145.9 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial Pectate_lyase_3 PF12708.7 EON95688.1 - 4.6e-60 203.1 20.1 5e-37 127.8 4.5 4.4 3 1 1 4 4 4 3 Pectate lyase superfamily protein End_N_terminal PF12218.8 EON95688.1 - 6.1e-06 25.8 1.3 0.081 12.6 0.4 3.2 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Varsurf_PPLC PF03490.13 EON95688.1 - 0.0017 18.3 0.3 0.0052 16.7 0.3 1.9 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C TerB_C PF15615.6 EON95688.1 - 0.13 12.6 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 TerB-C domain Peptidase_C14 PF00656.22 EON95689.1 - 9.9e-62 209.1 0.0 1.3e-61 208.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EON95689.1 - 0.2 11.6 0.3 1.8 8.5 0.0 2.5 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Cupin_1 PF00190.22 EON95690.1 - 3.4e-41 140.3 0.0 3.6e-21 75.4 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EON95690.1 - 2.9e-26 91.0 1.6 2.8e-13 49.4 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EON95690.1 - 5e-09 35.7 0.0 0.0004 20.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EON95690.1 - 2.2e-07 30.9 0.2 0.00092 19.1 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 EON95690.1 - 0.00081 19.3 0.0 0.052 13.4 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.12 EON95690.1 - 0.031 13.9 0.0 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase ARD PF03079.14 EON95690.1 - 0.043 14.0 0.8 1.5 9.0 0.1 2.3 2 0 0 2 2 2 0 ARD/ARD' family MFS_1 PF07690.16 EON95691.1 - 4.3e-22 78.5 32.9 7.2e-17 61.3 11.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON95691.1 - 7e-10 38.3 14.8 1.2e-09 37.6 14.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter DTHCT PF08070.11 EON95692.1 - 0.078 13.7 13.0 0.12 13.1 13.0 1.3 1 0 0 1 1 1 0 DTHCT (NUC029) region Roughex PF06020.11 EON95692.1 - 2.1 7.4 5.7 2.5 7.1 5.7 1.1 1 0 0 1 1 1 0 Drosophila roughex protein MRI PF15325.6 EON95692.1 - 5.7 8.1 8.0 9 7.4 8.0 1.3 1 0 0 1 1 1 0 Modulator of retrovirus infection MFS_1 PF07690.16 EON95694.1 - 3.9e-28 98.4 18.4 4.8e-28 98.1 18.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON95694.1 - 1.3e-08 34.1 6.7 1.8e-07 30.4 0.6 3.2 2 1 2 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.13 EON95694.1 - 4.7e-07 28.6 5.1 4.7e-07 28.6 5.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ArabFuran-catal PF09206.11 EON95695.1 - 1.9e-145 484.1 13.5 2.2e-145 483.9 13.5 1.0 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 EON95695.1 - 1.4e-10 41.3 0.0 2.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain APH PF01636.23 EON95696.1 - 1.6e-13 51.1 0.0 2.5e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EON95696.1 - 0.096 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 EON95696.1 - 0.23 10.7 0.0 1.7 7.9 0.0 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase Methyltransf_31 PF13847.6 EON95697.1 - 2.1e-22 79.5 0.0 2.9e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON95697.1 - 1.9e-21 76.6 0.0 3.2e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON95697.1 - 3.5e-20 72.5 0.0 5.4e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON95697.1 - 5.6e-17 62.1 0.0 8.3e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON95697.1 - 1e-13 51.9 0.0 1.6e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON95697.1 - 5e-10 39.1 0.0 7e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EON95697.1 - 4.2e-07 29.7 0.0 7.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EON95697.1 - 1.1e-05 25.0 0.0 2.8e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.19 EON95697.1 - 1.9e-05 24.5 0.0 2.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 EON95697.1 - 0.00011 22.2 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EON95697.1 - 0.00016 21.3 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_9 PF08003.11 EON95697.1 - 0.00024 20.1 0.0 0.00036 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EON95697.1 - 0.0011 18.4 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 EON95697.1 - 0.0014 18.3 0.0 0.0048 16.5 0.0 1.7 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 EON95697.1 - 0.0023 17.9 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EON95697.1 - 0.0058 16.1 0.0 0.0082 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 EON95697.1 - 0.021 13.9 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.16 EON95697.1 - 0.065 11.8 0.0 0.24 9.9 0.0 1.7 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.11 EON95697.1 - 0.07 12.7 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 Nodulation protein S (NodS) PBP PF01161.20 EON95698.1 - 1.9e-16 60.6 0.0 2.3e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ABC_tran PF00005.27 EON95700.1 - 1.6e-30 106.4 0.1 2.2e-30 105.9 0.1 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON95700.1 - 9.1e-08 32.3 0.4 0.00017 21.5 0.0 2.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON95700.1 - 8.5e-06 25.4 1.9 0.0041 16.6 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 EON95700.1 - 0.0038 17.3 1.0 0.0085 16.2 0.7 1.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_29 PF13555.6 EON95700.1 - 0.041 13.6 0.3 0.096 12.4 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EON95700.1 - 0.068 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 EON95700.1 - 0.1 12.7 0.1 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase MDD_C PF18376.1 EON95701.1 - 3.9e-63 212.6 0.0 5.9e-63 212.0 0.0 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EON95701.1 - 6.1e-10 39.2 2.4 9.3e-09 35.4 0.8 2.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF3248 PF11609.8 EON95701.1 - 0.079 12.9 0.2 3.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3248) Fe-S_biosyn PF01521.20 EON95702.1 - 2e-16 60.2 0.0 2.5e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis CPT_N PF16484.5 EON95702.1 - 0.024 14.6 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus Ndc1_Nup PF09531.10 EON95702.1 - 0.39 9.3 2.9 0.38 9.4 2.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MGC-24 PF05283.11 EON95702.1 - 6.5 7.2 9.1 9.2 6.7 9.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glyco_transf_54 PF04666.13 EON95703.1 - 1.3e-16 60.4 0.4 1.7e-13 50.1 0.3 3.0 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region YbhQ PF11076.8 EON95703.1 - 0.12 12.4 0.6 0.2 11.7 0.6 1.3 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ DUF2198 PF09964.9 EON95703.1 - 9.2 6.4 7.8 2.8 8.1 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) Abhydrolase_3 PF07859.13 EON95704.1 - 1.8e-29 103.1 0.0 2.7e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON95704.1 - 9.2e-05 23.1 2.5 0.00011 22.9 2.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EON95704.1 - 0.035 14.2 0.1 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Thioesterase domain COesterase PF00135.28 EON95704.1 - 0.097 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DUF3445 PF11927.8 EON95706.1 - 2.2e-61 207.4 0.0 2.5e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Alk_phosphatase PF00245.20 EON95707.1 - 3.7e-85 286.4 0.0 4.4e-85 286.1 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase adh_short PF00106.25 EON95710.1 - 2.2e-05 24.0 0.1 0.00022 20.8 0.0 2.1 1 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON95710.1 - 0.065 12.8 0.3 0.82 9.2 0.0 2.1 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase DUF647 PF04884.14 EON95711.1 - 1.9e-99 332.2 1.3 2.4e-99 331.8 1.3 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Rtt106 PF08512.12 EON95712.1 - 7.7e-31 106.4 0.0 1.6e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like bPH_2 PF03703.14 EON95712.1 - 0.00088 19.4 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial PH domain PH_18 PF18469.1 EON95712.1 - 0.0038 17.2 0.0 0.04 13.9 0.0 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain Paf1 PF03985.13 EON95712.1 - 5.3 5.9 14.2 7.4 5.5 14.2 1.2 1 0 0 1 1 1 0 Paf1 HhH-GPD PF00730.25 EON95713.1 - 3.6e-20 72.4 0.0 2.2e-19 69.9 0.0 2.0 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 EON95713.1 - 2.9e-13 49.8 0.0 8.9e-13 48.2 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain Beta-lactamase PF00144.24 EON95713.1 - 1.7e-07 30.8 0.0 3.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase HHH PF00633.23 EON95713.1 - 2.1e-05 24.1 0.1 5.6e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif DnaA_N PF11638.8 EON95713.1 - 0.14 12.0 0.3 1.3 8.9 0.1 2.2 2 0 0 2 2 2 0 DnaA N-terminal domain FMO-like PF00743.19 EON95714.1 - 3.6e-59 200.6 0.0 1.7e-51 175.3 0.0 2.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EON95714.1 - 1.3e-15 57.5 1.5 9e-12 44.9 0.0 3.3 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EON95714.1 - 1.4e-12 47.5 0.0 2e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON95714.1 - 2.7e-09 36.7 0.1 2.1e-07 30.4 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EON95714.1 - 1.1e-06 28.8 0.0 2.5e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EON95714.1 - 4.9e-05 23.1 0.0 0.17 11.5 0.1 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EON95714.1 - 5.9e-05 23.5 1.7 0.023 15.2 0.3 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EON95714.1 - 9.4e-05 22.4 0.6 1.9 8.5 0.0 4.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EON95714.1 - 0.016 15.3 0.3 1.5 8.8 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 EON95714.1 - 0.035 13.7 0.0 5 6.7 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 EON95714.1 - 0.04 14.4 0.0 4.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding NOD2_WH PF17779.1 EON95714.1 - 0.048 14.0 0.0 0.089 13.1 0.0 1.4 1 0 0 1 1 1 0 NOD2 winged helix domain FAD_binding_3 PF01494.19 EON95714.1 - 0.058 12.6 0.0 0.058 12.6 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.19 EON95714.1 - 0.094 12.1 0.1 13 5.1 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 EON95714.1 - 0.095 11.9 0.2 0.26 10.5 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Spherulin4 PF12138.8 EON95716.1 - 9.2e-71 238.3 0.0 1e-70 238.1 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Pyr_redox_2 PF07992.14 EON95717.1 - 3.1e-32 112.0 0.1 3.8e-32 111.7 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON95717.1 - 6.5e-11 42.6 0.3 1.3e-07 32.1 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EON95717.1 - 0.0021 18.1 0.7 18 5.3 0.0 3.7 3 1 1 4 4 4 3 FAD-NAD(P)-binding NADPH_Ox PF08414.10 EON95718.1 - 0.088 13.2 1.1 0.36 11.2 1.1 1.8 1 1 0 1 1 1 0 Respiratory burst NADPH oxidase WD40 PF00400.32 EON95719.1 - 5.8e-52 172.5 15.6 6.9e-09 36.2 0.9 8.6 8 2 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON95719.1 - 1.4e-11 44.5 0.0 0.0014 18.9 0.0 4.7 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EON95719.1 - 5.1e-08 32.0 0.0 0.0016 17.2 0.0 3.5 4 0 0 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EON95719.1 - 1.8e-05 23.7 0.0 0.2 10.4 0.0 3.2 3 0 0 3 3 3 3 Nup133 N terminal like Cytochrom_D1 PF02239.16 EON95719.1 - 0.15 10.6 0.0 3.2 6.2 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain Globin PF00042.22 EON95720.1 - 4.9e-09 36.7 0.0 8.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.21 EON95720.1 - 1.8e-08 35.0 0.0 3.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EON95720.1 - 3.8e-07 30.4 0.0 8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 EON95720.1 - 8.6e-05 22.5 0.1 0.0002 21.3 0.0 1.5 1 1 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 EON95720.1 - 0.0012 19.0 0.1 0.52 10.4 0.0 3.1 2 1 1 3 3 3 1 Ferric reductase NAD binding domain p450 PF00067.22 EON95721.1 - 2.4e-81 273.8 0.0 2.9e-81 273.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PsaF PF17550.2 EON95721.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function Sugar_tr PF00083.24 EON95722.1 - 2.4e-33 115.7 6.4 4.5e-28 98.3 0.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EON95722.1 - 0.00093 18.2 7.6 0.008 15.1 4.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF438 PF04282.13 EON95722.1 - 0.31 11.0 2.2 20 5.2 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF438) SdpI PF13630.6 EON95722.1 - 5.9 7.1 6.1 1 9.5 0.1 2.5 1 1 1 2 2 2 0 SdpI/YhfL protein family FAD_binding_4 PF01565.23 EON95724.1 - 6.3e-20 71.3 0.4 1.3e-19 70.3 0.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EON95724.1 - 0.0085 16.2 0.1 0.02 15.0 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like AftA_N PF12250.8 EON95724.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal PhyH PF05721.13 EON95725.1 - 3e-17 63.6 0.0 3.9e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.16 EON95725.1 - 0.014 15.2 0.2 0.84 9.4 0.0 2.2 2 0 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.24 EON95726.1 - 3.4e-106 355.8 14.5 4.1e-106 355.6 14.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON95726.1 - 8.9e-26 90.6 42.8 2.6e-23 82.5 20.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 EON95726.1 - 0.0093 14.9 0.2 0.0093 14.9 0.2 1.7 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM OPT PF03169.15 EON95727.1 - 2.4e-176 588.0 49.1 2.7e-176 587.8 49.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Holin_SPP1 PF04688.13 EON95727.1 - 8 6.7 7.0 6.9 6.9 1.7 3.5 3 0 0 3 3 3 0 SPP1 phage holin RasGEF PF00617.19 EON95728.1 - 8.5e-51 172.6 0.0 1.2e-50 172.2 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EON95728.1 - 0.068 13.4 0.0 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 RasGEF N-terminal motif adh_short PF00106.25 EON95729.1 - 3.2e-32 111.6 0.0 3.8e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON95729.1 - 5.9e-18 65.3 0.0 7.5e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON95729.1 - 4.8e-07 29.9 0.1 1.4e-06 28.3 0.1 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EON95729.1 - 8.3e-06 25.4 0.0 1.2e-05 24.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EON95729.1 - 0.0047 16.8 0.0 0.0072 16.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding ApbA PF02558.16 EON95729.1 - 0.021 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 EON95729.1 - 0.026 14.8 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 EON95729.1 - 0.043 14.0 0.0 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EON95729.1 - 0.054 13.6 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EON95729.1 - 0.1 13.2 0.0 0.38 11.4 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AA_permease PF00324.21 EON95730.1 - 1.5e-80 271.1 25.7 1.8e-80 270.8 25.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON95730.1 - 5.3e-24 84.8 25.0 6.4e-24 84.6 25.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4077 PF13295.6 EON95730.1 - 0.0015 18.5 3.1 0.003 17.5 3.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4077) GH131_N PF18271.1 EON95731.1 - 1.4e-59 201.9 1.6 1.7e-59 201.6 1.6 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CLASP_N PF12348.8 EON95732.1 - 2e-07 30.8 0.0 1.4e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.22 EON95732.1 - 4.2e-06 26.6 1.6 1.2 9.6 0.1 5.6 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 EON95732.1 - 3.8e-05 23.8 0.0 0.016 15.3 0.0 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 TAN PF11640.8 EON95732.1 - 0.0038 17.4 0.1 0.014 15.5 0.1 2.0 1 1 0 1 1 1 1 Telomere-length maintenance and DNA damage repair Adaptin_N PF01602.20 EON95732.1 - 0.006 15.2 0.2 3.9 5.9 0.0 2.7 2 1 1 3 3 3 2 Adaptin N terminal region HALZ PF02183.18 EON95732.1 - 0.026 14.7 9.6 0.053 13.8 3.5 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper GHMP_kinases_C PF08544.13 EON95732.1 - 0.072 13.5 1.3 6.9 7.1 0.3 3.2 2 1 0 2 2 2 0 GHMP kinases C terminal CCDC144C PF14915.6 EON95732.1 - 0.19 10.8 8.7 0.36 9.9 8.7 1.4 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region NYD-SP28_assoc PF14775.6 EON95732.1 - 0.29 11.3 1.0 1.2 9.3 0.4 2.4 1 1 0 1 1 1 0 Sperm tail C-terminal domain DUF812 PF05667.11 EON95732.1 - 2.8 6.7 7.8 5.6 5.7 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SHE3 PF17078.5 EON95732.1 - 3.8 7.2 7.3 8.7 6.0 7.3 1.5 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_1 PF00170.21 EON95732.1 - 7 6.8 9.6 3 8.0 1.3 3.9 4 0 0 4 4 4 0 bZIP transcription factor Dioxygenase_N PF04444.14 EON95734.1 - 5.6e-26 90.2 0.2 8.6e-26 89.6 0.2 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Dioxygenase_C PF00775.21 EON95734.1 - 2e-21 76.3 0.0 2.9e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase CarboxypepD_reg PF13620.6 EON95734.1 - 0.00082 19.6 0.0 0.0017 18.5 0.0 1.5 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF1992 PF09350.10 EON95735.1 - 6.5e-21 74.3 0.3 2.1e-20 72.6 0.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) SAPS PF04499.15 EON95736.1 - 2.6e-188 626.8 2.1 1.5e-187 624.3 0.0 2.7 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein Sld5 PF05916.11 EON95737.1 - 2.8e-19 69.6 0.0 5.7e-19 68.6 0.0 1.5 2 0 0 2 2 2 1 GINS complex protein FAD_binding_4 PF01565.23 EON95738.1 - 1.4e-21 76.7 0.0 2.9e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Aldo_ket_red PF00248.21 EON95739.1 - 1.3e-51 175.6 0.0 5.4e-51 173.5 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1286 PF06939.11 EON95740.1 - 0.0096 16.2 0.4 0.16 12.2 0.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1286) HET PF06985.11 EON95741.1 - 6.6e-22 78.4 0.6 1.1e-21 77.8 0.6 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.6 EON95742.1 - 8.9e-52 176.0 0.0 1e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON95742.1 - 2.6e-41 141.3 0.0 3e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON95742.1 - 4.5e-07 29.9 0.1 6.2e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EON95742.1 - 0.0022 17.4 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EON95742.1 - 0.015 14.8 0.0 0.031 13.7 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EON95742.1 - 0.24 11.3 1.5 0.4 10.5 1.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Aldo_ket_red PF00248.21 EON95744.1 - 4.6e-28 98.3 0.0 5.1e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GCFC PF07842.12 EON95745.1 - 3e-79 266.5 9.1 3e-79 266.5 9.1 1.9 1 1 1 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EON95745.1 - 1.1e-14 54.0 2.1 3.1e-14 52.6 2.1 1.8 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 EON95745.1 - 2.7e-11 43.8 13.9 2.7e-11 43.8 13.9 2.8 2 1 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 EON95745.1 - 2.2e-07 30.9 0.7 2.2e-07 30.9 0.7 2.3 3 0 0 3 3 3 1 G-patch domain FUSC PF04632.12 EON95745.1 - 0.14 10.6 3.1 0.22 10.0 3.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nop14 PF04147.12 EON95745.1 - 7 4.7 22.1 1.6 6.9 4.6 2.3 2 0 0 2 2 2 0 Nop14-like family SUZ PF12752.7 EON95745.1 - 7.8 7.3 12.0 0.29 11.9 0.2 3.5 3 0 0 3 3 3 0 SUZ domain Fungal_trans_2 PF11951.8 EON95746.1 - 5.7e-16 58.3 0.0 1e-15 57.5 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EON95746.1 - 8.6e-08 32.2 8.7 8.6e-08 32.2 8.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 EON95747.1 - 8e-22 78.2 0.0 1.3e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 EON95749.1 - 0.0032 16.5 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyto_heme_lyase PF01265.17 EON95750.1 - 2.3e-40 139.0 10.0 7.9e-39 134.0 10.0 2.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase WW PF00397.26 EON95751.1 - 1.1e-06 28.6 3.3 2.5e-06 27.4 3.3 1.7 1 0 0 1 1 1 1 WW domain KinB_sensor PF16767.5 EON95751.1 - 0.014 15.8 3.8 0.024 15.1 3.8 1.2 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB DUF2076 PF09849.9 EON95751.1 - 0.1 12.6 14.8 0.22 11.5 14.8 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4404 PF14357.6 EON95751.1 - 0.45 11.2 5.2 0.85 10.3 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) TPR_2 PF07719.17 EON95751.1 - 1.1 9.5 5.7 4.3 7.7 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EON95751.1 - 5.2 7.1 7.1 1.3 9.0 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat LisH_TPL PF17814.1 EON95752.1 - 0.036 13.7 0.1 0.24 11.1 0.0 2.2 1 1 1 2 2 2 0 LisH-like dimerisation domain LisH PF08513.11 EON95752.1 - 0.087 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 LisH DUF3870 PF12986.7 EON95753.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) FAD_binding_3 PF01494.19 EON95754.1 - 1.2e-21 77.3 0.1 4.1e-10 39.5 0.1 2.4 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EON95754.1 - 1.6e-08 34.1 1.3 1.2e-05 24.7 0.4 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON95754.1 - 1.4e-07 31.6 0.3 3.3e-07 30.4 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EON95754.1 - 3.6e-07 29.6 0.7 6.1e-07 28.9 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EON95754.1 - 1.5e-06 27.8 0.2 2.2e-06 27.3 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EON95754.1 - 1.6e-06 27.1 0.1 2.3e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EON95754.1 - 3.4e-06 27.5 0.1 1.6e-05 25.3 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EON95754.1 - 6.3e-06 26.0 1.2 5.9e-05 22.8 0.3 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EON95754.1 - 2.6e-05 23.7 0.1 0.038 13.3 0.1 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 EON95754.1 - 0.00023 20.1 0.9 0.00045 19.2 0.2 1.7 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 EON95754.1 - 0.00065 19.0 0.0 0.00099 18.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EON95754.1 - 0.0009 18.4 0.9 0.0014 17.8 0.9 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EON95754.1 - 0.0012 18.2 0.1 0.002 17.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EON95754.1 - 0.0033 16.7 0.2 0.0054 16.1 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EON95754.1 - 0.013 14.6 0.3 0.013 14.6 0.3 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein Glyco_trans_4_4 PF13579.6 EON95754.1 - 0.022 15.2 1.1 2.5 8.5 0.1 2.4 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain NAD_binding_7 PF13241.6 EON95754.1 - 0.023 15.1 0.1 0.049 14.1 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 EON95754.1 - 0.077 12.6 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glu_dehyd_C PF16912.5 EON95754.1 - 0.12 11.8 0.1 0.21 11.1 0.1 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 EON95754.1 - 0.13 11.9 0.2 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain YjeF_N PF03853.15 EON95754.1 - 0.13 12.1 0.1 0.45 10.4 0.1 1.8 2 0 0 2 2 2 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 EON95754.1 - 0.19 11.6 0.2 0.31 10.9 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EON95754.1 - 0.23 11.4 0.8 0.72 9.8 0.2 2.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Fungal_trans PF04082.18 EON95755.1 - 1.5e-11 43.9 0.0 2.8e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Xan_ur_permease PF00860.20 EON95756.1 - 1.2e-23 83.5 28.9 1e-13 50.8 9.6 3.2 3 0 0 3 3 3 3 Permease family MFS_MOT1 PF16983.5 EON95756.1 - 0.62 10.5 15.7 0.042 14.2 5.3 2.8 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Med26 PF08711.11 EON95757.1 - 1e-10 41.5 0.0 2.4e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Glyco_hydro_61 PF03443.14 EON95758.1 - 1.3e-53 182.0 1.3 1.5e-53 181.8 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ldi PF18566.1 EON95759.1 - 2.1e-33 116.2 0.0 2.4e-22 79.9 0.0 2.1 1 1 1 2 2 2 2 Linalool dehydratase/isomerase Sterol_MT_C PF08498.10 EON95760.1 - 7.8e-27 93.4 0.5 1.6e-26 92.4 0.5 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EON95760.1 - 3.1e-20 72.6 0.0 6.1e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON95760.1 - 5.6e-19 68.6 0.0 1.2e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON95760.1 - 1.1e-17 64.3 0.0 1.5e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON95760.1 - 5.9e-12 45.7 0.0 9e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON95760.1 - 8.9e-11 42.4 0.1 2.7e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EON95760.1 - 1.1e-10 41.3 0.0 1.6e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EON95760.1 - 2.1e-10 40.3 0.0 3.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EON95760.1 - 0.00041 20.2 0.0 0.00068 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EON95760.1 - 0.00054 19.5 0.0 0.0012 18.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EON95760.1 - 0.0007 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 EON95760.1 - 0.0034 17.0 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.20 EON95760.1 - 0.0063 15.6 0.0 0.009 15.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 EON95760.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain NodS PF05401.11 EON95760.1 - 0.075 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) FAM177 PF14774.6 EON95760.1 - 0.082 13.3 0.6 0.32 11.4 0.2 2.0 2 0 0 2 2 2 0 FAM177 family MetW PF07021.12 EON95760.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 EON95760.1 - 0.16 11.5 0.0 0.37 10.2 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase RRM_1 PF00076.22 EON95761.1 - 2.4e-10 40.1 0.0 4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EON95761.1 - 0.00025 20.9 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EON95761.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 EON95761.1 - 0.0024 17.8 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Brr6_like_C_C PF10104.9 EON95762.1 - 6.9e-43 145.6 0.9 8.9e-43 145.3 0.9 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Transket_pyr PF02779.24 EON95764.1 - 1.2e-45 155.4 0.0 1.7e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EON95764.1 - 3.6e-35 120.5 0.1 1.1e-34 119.0 0.1 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain Aminotran_5 PF00266.19 EON95764.1 - 0.039 12.9 0.0 0.071 12.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V FtsA PF14450.6 EON95764.1 - 0.071 13.5 0.0 0.23 11.9 0.0 1.8 2 0 0 2 2 2 0 Cell division protein FtsA Spore_IV_A PF09547.10 EON95764.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Y_phosphatase3 PF13350.6 EON95765.1 - 3.9e-59 200.4 0.0 4.5e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EON95765.1 - 5.2e-05 22.9 0.0 7.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EON95765.1 - 0.0011 18.6 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EON95765.1 - 0.034 14.0 0.0 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 EON95765.1 - 0.088 11.7 0.1 0.17 10.8 0.1 1.4 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Pex16 PF08610.10 EON95766.1 - 1.7e-141 471.1 0.0 1.9e-141 470.9 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) bZIP_2 PF07716.15 EON95767.1 - 1.1e-07 31.8 12.3 2.2e-07 30.9 12.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EON95767.1 - 0.00018 21.6 15.6 0.0003 20.8 15.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EON95767.1 - 0.064 13.8 11.1 0.11 13.0 11.1 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Phytase-like PF13449.6 EON95768.1 - 1.2e-35 123.9 0.0 1.6e-35 123.4 0.0 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.11 EON95768.1 - 0.11 11.8 0.0 3 7.0 0.0 2.4 2 0 0 2 2 2 0 SdiA-regulated GST_N_2 PF13409.6 EON95769.1 - 1.5e-15 57.2 0.0 3.8e-15 55.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EON95769.1 - 6e-15 55.4 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EON95769.1 - 3.6e-13 49.6 0.0 6.2e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EON95769.1 - 0.00034 20.8 0.0 0.00059 20.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.6 EON95769.1 - 0.0049 17.0 0.0 0.0081 16.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EON95769.1 - 0.008 16.2 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SWIRM PF04433.17 EON95770.1 - 4.9e-14 52.4 0.0 3.1e-12 46.7 0.0 2.3 2 0 0 2 2 2 2 SWIRM domain B277 PF17623.2 EON95771.1 - 0.14 11.3 0.6 0.15 11.1 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF899 PF05988.12 EON95772.1 - 1.9e-70 236.8 0.0 2.3e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA PF00578.21 EON95772.1 - 2.8e-05 24.0 0.0 4.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EON95772.1 - 0.04 13.6 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Redoxin DUF1691 PF07950.11 EON95773.1 - 5.3e-37 126.8 10.9 1.4e-32 112.6 5.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Aldo_ket_red PF00248.21 EON95774.1 - 2e-66 224.2 0.0 2.5e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_zinc_N PF00107.26 EON95775.1 - 1.1e-21 77.1 1.3 1.5e-21 76.7 0.3 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON95775.1 - 5.2e-21 74.6 0.6 9.3e-21 73.8 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EON95775.1 - 9.9e-06 26.6 0.2 2.1e-05 25.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RAC_head PF16717.5 EON95776.1 - 1e-31 109.8 4.5 1e-31 109.8 4.5 3.6 3 1 1 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 EON95776.1 - 3.3e-19 68.8 2.2 3.3e-19 68.8 2.2 2.6 2 0 0 2 2 2 1 DnaJ domain TraH PF06122.11 EON95776.1 - 0.42 9.8 4.5 0.68 9.2 4.5 1.3 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein PP-binding PF00550.25 EON95777.1 - 2.4e-07 31.0 0.1 4.2e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site Complex1_LYR PF05347.15 EON95778.1 - 0.00011 22.1 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EON95778.1 - 0.017 15.8 0.0 0.049 14.4 0.0 1.6 1 1 1 2 2 2 0 Complex1_LYR-like Complex1_LYR_1 PF13232.6 EON95778.1 - 0.15 12.7 0.3 0.21 12.2 0.3 1.4 1 1 0 1 1 1 0 Complex1_LYR-like DSHCT PF08148.12 EON95779.1 - 4.5e-53 179.3 0.3 9.9e-53 178.2 0.3 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EON95779.1 - 6.5e-40 136.1 0.0 1.3e-38 131.8 0.0 2.4 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 EON95779.1 - 3e-31 109.3 0.1 6.2e-31 108.3 0.1 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EON95779.1 - 3.9e-18 65.8 0.0 1.1e-17 64.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON95779.1 - 6.5e-06 26.5 0.0 2e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON95779.1 - 4.7e-05 23.5 0.2 0.00031 20.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C2H2_jaz PF12171.8 EON95780.1 - 1.1e-07 32.0 3.7 1.7e-07 31.3 3.7 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EON95780.1 - 0.00014 22.1 0.9 0.00023 21.4 0.9 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EON95780.1 - 0.022 15.1 0.3 0.035 14.4 0.3 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EON95780.1 - 0.081 13.4 0.8 0.14 12.7 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EON95780.1 - 0.12 13.3 0.3 0.22 12.4 0.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger DUF2057 PF09829.9 EON95780.1 - 0.18 11.9 0.1 0.28 11.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) zf-DBF PF07535.12 EON95780.1 - 0.3 11.2 2.4 0.54 10.4 2.4 1.4 1 0 0 1 1 1 0 DBF zinc finger MFS_1 PF07690.16 EON95781.1 - 3.8e-30 105.0 8.8 4.3e-30 104.8 8.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON95781.1 - 1e-10 41.1 5.5 1.4e-10 40.6 5.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EON95781.1 - 0.00054 19.4 1.6 0.00069 19.0 1.6 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Acetyltransf_10 PF13673.7 EON95782.1 - 2.6e-10 40.3 0.0 3.4e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON95782.1 - 8.8e-08 32.4 0.0 1.2e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON95782.1 - 5e-07 30.1 0.0 7.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EON95782.1 - 5.2e-06 26.3 0.0 6.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EON95782.1 - 0.00012 22.2 0.0 0.00015 21.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EON95782.1 - 0.0013 18.8 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase adh_short PF00106.25 EON95783.1 - 9.8e-23 80.6 0.1 5.9e-16 58.5 0.1 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON95783.1 - 1.8e-14 53.9 0.1 3.1e-11 43.3 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EON95783.1 - 1.8e-05 24.3 0.0 0.0034 16.9 0.1 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EON95783.1 - 0.0031 17.1 0.2 0.0049 16.5 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family NADH-u_ox-rdase PF10785.9 EON95784.1 - 4e-30 104.3 0.1 6.9e-30 103.6 0.1 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 EON95784.1 - 2.3e-26 91.6 0.1 3.3e-26 91.1 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Snf7 PF03357.21 EON95785.1 - 2.5e-07 30.4 28.6 2.5e-07 30.4 28.6 1.6 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 EON95785.1 - 0.056 13.4 10.5 0.089 12.7 10.5 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway 3-dmu-9_3-mt PF06983.13 EON95785.1 - 0.47 11.0 4.7 0.32 11.5 2.5 1.9 1 1 0 1 1 1 0 3-demethylubiquinone-9 3-methyltransferase CEL_III_C PF18054.1 EON95785.1 - 0.75 9.8 10.0 0.48 10.5 7.4 1.8 1 1 1 2 2 2 0 CEL-III C-terminal RFamide_26RFa PF11109.8 EON95785.1 - 1.3 9.6 13.3 0.2 12.2 1.9 2.2 1 1 1 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 adh_short PF00106.25 EON95786.1 - 2.8e-42 144.4 1.1 4e-42 143.9 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON95786.1 - 1.7e-39 135.8 1.1 2.5e-39 135.2 1.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON95786.1 - 2.6e-08 34.0 2.2 3.8e-08 33.4 0.6 1.9 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 EON95786.1 - 0.0036 17.3 0.1 0.0065 16.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 EON95786.1 - 0.0064 16.6 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Tubulin_C PF03953.17 EON95787.1 - 0.0037 17.4 0.1 0.015 15.5 0.0 2.1 3 0 0 3 3 3 1 Tubulin C-terminal domain DUF4944 PF16302.5 EON95787.1 - 0.17 12.0 0.1 2.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4944) YscO PF07321.12 EON95787.1 - 1 9.3 11.2 7.7 6.5 3.0 3.1 3 0 0 3 3 3 0 Type III secretion protein YscO TPR_MLP1_2 PF07926.12 EON95787.1 - 7.6 6.6 8.2 13 5.8 0.3 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein OEP PF02321.18 EON95788.1 - 0.021 14.7 3.2 0.033 14.0 3.2 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein DUF5536 PF17688.1 EON95788.1 - 0.037 13.9 6.0 0.046 13.6 6.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5536) Bot1p PF12298.8 EON95789.1 - 2.4e-52 177.6 2.3 2.6e-52 177.5 1.9 1.3 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein DUF3071 PF11268.8 EON95789.1 - 0.059 13.4 0.5 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3071) DUF4334 PF14232.6 EON95790.1 - 1.9e-28 98.2 1.6 2.2e-28 98.0 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4334) GXWXG PF14231.6 EON95790.1 - 6.6e-28 96.6 0.5 9.8e-28 96.0 0.5 1.3 1 0 0 1 1 1 1 GXWXG protein Myosin_tail_1 PF01576.19 EON95791.1 - 1.2e-07 30.0 63.7 3.3e-06 25.3 44.7 2.1 1 1 1 2 2 2 2 Myosin tail Fez1 PF06818.15 EON95791.1 - 2.5e-06 28.1 54.5 0.00069 20.1 8.5 4.2 1 1 1 3 3 3 2 Fez1 Spc7 PF08317.11 EON95791.1 - 8.4e-06 24.9 66.9 0.004 16.1 22.7 3.8 1 1 2 3 3 3 3 Spc7 kinetochore protein Filament PF00038.21 EON95791.1 - 0.00024 20.8 56.2 0.04 13.5 12.6 4.1 1 1 3 4 4 4 3 Intermediate filament protein AAA_13 PF13166.6 EON95791.1 - 0.00033 19.5 24.4 0.00033 19.5 24.4 2.3 1 1 1 2 2 2 1 AAA domain Baculo_PEP_C PF04513.12 EON95791.1 - 0.0017 18.4 32.8 0.019 15.0 10.9 4.8 2 1 5 7 7 6 3 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 EON95791.1 - 0.0018 18.5 70.3 0.2 11.9 17.9 4.8 1 1 1 3 3 3 1 Autophagy protein 16 (ATG16) DUF5082 PF16888.5 EON95791.1 - 0.0023 18.2 40.7 0.095 13.0 14.9 5.6 1 1 4 5 5 5 1 Domain of unknown function (DUF5082) CALCOCO1 PF07888.11 EON95791.1 - 0.0025 16.7 39.3 0.0025 16.7 39.3 2.5 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like Rootletin PF15035.6 EON95791.1 - 0.0029 17.6 55.3 0.036 14.1 14.5 4.9 1 1 3 4 4 4 1 Ciliary rootlet component, centrosome cohesion BRE1 PF08647.11 EON95791.1 - 0.0054 16.8 64.2 0.48 10.5 4.4 6.9 1 1 5 6 6 6 3 BRE1 E3 ubiquitin ligase CENP-F_leu_zip PF10473.9 EON95791.1 - 0.0085 16.1 5.3 0.0085 16.1 5.3 4.9 1 1 4 5 5 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HrpB7 PF09486.10 EON95791.1 - 0.017 15.5 13.1 0.017 15.5 13.1 3.8 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 EON95791.1 - 0.023 14.7 34.7 0.12 12.4 3.0 5.1 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) MAD PF05557.13 EON95791.1 - 0.037 12.4 58.6 1.7 6.9 17.5 3.4 1 1 2 3 3 3 0 Mitotic checkpoint protein Atg14 PF10186.9 EON95791.1 - 0.045 12.8 50.9 0.025 13.7 12.6 3.4 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 EON95791.1 - 0.076 12.5 56.2 0.033 13.7 26.9 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 HMMR_N PF15905.5 EON95791.1 - 0.088 12.3 64.3 0.013 15.0 42.9 2.9 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal NPV_P10 PF05531.12 EON95791.1 - 0.14 12.6 31.9 0.12 12.8 1.5 5.9 4 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.8 EON95791.1 - 0.16 9.4 54.2 0.1 10.1 39.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) APG6_N PF17675.1 EON95791.1 - 0.36 11.4 80.3 0.056 14.0 14.8 5.5 1 1 1 2 2 1 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 EON95791.1 - 0.49 10.4 70.6 1.9 8.6 14.4 4.9 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Cast PF10174.9 EON95791.1 - 0.58 8.3 59.5 0.029 12.6 43.7 2.7 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone DUF4201 PF13870.6 EON95791.1 - 0.96 9.2 50.4 0.76 9.5 10.0 5.7 1 1 4 5 5 5 0 Domain of unknown function (DUF4201) DHR10 PF18595.1 EON95791.1 - 1.9 8.6 64.0 0.059 13.4 12.7 4.9 1 1 4 5 5 5 0 Designed helical repeat protein 10 domain DUF812 PF05667.11 EON95791.1 - 2.3 7.0 50.2 30 3.3 48.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) FPP PF05911.11 EON95791.1 - 2.4 6.2 59.2 0.64 8.1 6.5 3.7 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil TolA_bind_tri PF16331.5 EON95791.1 - 2.4 8.3 34.8 2 8.6 2.5 5.2 2 2 3 5 5 5 0 TolA binding protein trimerisation UPF0242 PF06785.11 EON95791.1 - 2.7 8.0 64.7 6.8 6.7 36.1 4.5 2 1 2 4 4 3 0 Uncharacterised protein family (UPF0242) N-terminus COMP PF11598.8 EON95791.1 - 3.6 8.1 9.2 0.55 10.7 0.6 3.4 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein Phage_connect_1 PF05135.13 EON95791.1 - 3.8 8.1 15.5 0.093 13.2 3.9 3.9 3 1 1 4 4 2 0 Phage gp6-like head-tail connector protein MscS_porin PF12795.7 EON95791.1 - 4.5 6.7 62.1 0.022 14.3 10.2 3.7 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain DUF724 PF05266.14 EON95791.1 - 4.5 7.0 52.2 0.1 12.4 15.2 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF724) COG5 PF10392.9 EON95791.1 - 5 7.3 29.0 0.51 10.5 6.1 4.1 1 1 3 4 4 4 0 Golgi transport complex subunit 5 GAS PF13851.6 EON95791.1 - 7.3 5.9 59.1 0.61 9.4 11.3 3.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Glyoxalase PF00903.25 EON95793.1 - 1.5e-09 38.1 0.3 6.7e-07 29.6 0.3 2.2 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EON95793.1 - 0.11 12.8 0.1 3.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short PF00106.25 EON95794.1 - 2e-16 60.1 0.1 2.2e-16 59.9 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON95794.1 - 6.2e-14 52.1 0.1 7.8e-14 51.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON95794.1 - 7.3e-09 35.8 0.1 9.1e-09 35.5 0.1 1.0 1 0 0 1 1 1 1 KR domain PhrC_PhrF PF11131.8 EON95794.1 - 0.1 12.2 0.0 0.32 10.6 0.0 1.8 1 0 0 1 1 1 0 Rap-phr extracellular signalling ADIP PF11559.8 EON95795.1 - 0.0075 16.4 9.4 0.0075 16.4 9.4 3.4 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 EON95795.1 - 0.037 14.1 1.8 0.037 14.1 1.8 4.2 3 1 1 4 4 4 0 bZIP transcription factor DivIVA PF05103.13 EON95795.1 - 0.039 14.0 22.0 6.7 6.8 17.1 3.4 2 1 0 2 2 2 0 DivIVA protein Tropomyosin PF00261.20 EON95795.1 - 0.081 12.3 27.7 0.026 13.9 16.2 2.8 1 1 1 2 2 2 0 Tropomyosin PKcGMP_CC PF16808.5 EON95795.1 - 0.11 12.4 0.3 0.11 12.4 0.3 4.3 5 0 0 5 5 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF5082 PF16888.5 EON95795.1 - 0.12 12.6 20.6 0.18 12.1 9.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) THP2 PF09432.10 EON95795.1 - 0.14 12.2 5.5 0.27 11.3 0.2 2.8 3 0 0 3 3 3 0 Tho complex subunit THP2 TMF_TATA_bd PF12325.8 EON95795.1 - 0.46 10.7 32.3 0.76 10.0 6.7 4.1 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 EON95795.1 - 0.53 9.5 30.3 0.056 12.7 8.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) Striatin PF08232.12 EON95795.1 - 0.68 10.5 21.9 3.1 8.4 5.1 3.3 1 1 1 2 2 2 0 Striatin family ATG16 PF08614.11 EON95795.1 - 1.2 9.3 36.9 0.21 11.8 11.9 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) ERM PF00769.19 EON95795.1 - 1.3 8.8 37.0 1.4e+02 2.1 36.3 2.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Fib_alpha PF08702.10 EON95795.1 - 1.6 8.9 16.8 0.55 10.4 3.4 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Leu_zip PF15294.6 EON95795.1 - 1.7 8.1 22.5 1.9 8.0 14.9 2.5 1 1 1 2 2 2 0 Leucine zipper Med9 PF07544.13 EON95795.1 - 2.5 8.3 18.0 0.08 13.0 3.3 4.1 2 1 3 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 V_ATPase_I PF01496.19 EON95795.1 - 2.7 5.8 17.0 1.6 6.5 7.0 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family KASH_CCD PF14662.6 EON95795.1 - 3.9 7.3 26.3 1.3 8.8 11.5 3.1 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH SHE3 PF17078.5 EON95795.1 - 4.1 7.0 18.5 0.32 10.7 4.0 2.8 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Lectin_N PF03954.14 EON95795.1 - 4.6 7.0 13.3 0.68 9.7 0.7 3.1 2 1 2 4 4 4 0 Hepatic lectin, N-terminal domain Nuc_N PF14448.6 EON95795.1 - 4.7 7.2 5.9 3.7 7.5 0.1 3.0 3 1 0 3 3 3 0 Nuclease N terminal HALZ PF02183.18 EON95795.1 - 5 7.4 12.1 14 6.0 0.8 4.1 3 1 1 4 4 4 0 Homeobox associated leucine zipper Tropomyosin_1 PF12718.7 EON95795.1 - 5.7 7.1 31.3 5.6 7.1 9.3 3.0 1 1 2 3 3 3 0 Tropomyosin like CHD5 PF04420.14 EON95795.1 - 6 6.7 6.6 4.9 7.0 4.5 2.0 1 1 1 2 2 2 0 CHD5-like protein DUF4472 PF14739.6 EON95795.1 - 8 7.3 26.3 2.5 8.9 7.3 3.5 2 1 2 4 4 3 0 Domain of unknown function (DUF4472) adh_short_C2 PF13561.6 EON95796.1 - 2e-39 135.5 0.0 4e-39 134.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON95796.1 - 8.4e-39 133.0 0.0 1.4e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON95796.1 - 9e-11 42.0 0.3 1.7e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 EON95796.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 EON95796.1 - 0.014 15.4 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EON95796.1 - 0.025 13.9 0.1 0.047 13.0 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 EON95796.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family WASH-7_C PF14746.6 EON95797.1 - 0.0022 17.7 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal Vma12 PF11712.8 EON95797.1 - 5 7.2 4.9 3.4 7.7 0.9 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Aldedh PF00171.22 EON95798.1 - 2.8e-45 154.7 0.0 3.1e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pyr_redox_2 PF07992.14 EON95799.1 - 9.7e-53 179.3 2.8 1.4e-52 178.8 2.8 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EON95799.1 - 2.7e-15 56.1 0.0 6.7e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 EON95799.1 - 1.9e-13 50.7 0.1 1.9e-13 50.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON95799.1 - 1.2e-08 34.6 0.1 0.0041 16.4 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 EON95799.1 - 3.9e-06 27.3 0.0 9.9e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.6 EON95799.1 - 0.00032 20.0 0.1 0.68 9.0 0.0 2.4 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EON95799.1 - 0.0096 14.7 1.5 2.7 6.6 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein DUF1188 PF06690.11 EON95799.1 - 0.037 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) NAD_binding_9 PF13454.6 EON95799.1 - 0.041 13.9 3.0 5.5 7.0 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EON95799.1 - 0.17 12.3 0.5 16 6.0 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Glyco_hydro_28 PF00295.17 EON95800.1 - 4e-116 387.6 21.5 4.7e-116 387.4 21.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 E1-E2_ATPase PF00122.20 EON95801.1 - 1e-47 162.0 0.0 8.5e-47 159.0 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EON95801.1 - 1.3e-32 113.9 0.0 2.3e-32 113.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EON95801.1 - 2e-30 105.0 0.2 4.8e-13 49.3 0.0 3.5 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EON95801.1 - 0.00069 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Caveolin PF01146.17 EON95801.1 - 0.14 12.1 4.8 1.8 8.5 0.4 2.5 2 0 0 2 2 2 0 Caveolin HAD PF12710.7 EON95801.1 - 0.14 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DAO PF01266.24 EON95802.1 - 6.1e-40 137.9 1.8 7.5e-40 137.6 1.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 EON95802.1 - 1.8e-11 43.8 0.0 6.4e-11 42.0 0.0 2.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.6 EON95802.1 - 2.6e-08 34.0 0.2 5.6e-08 32.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EON95802.1 - 6.3e-07 28.9 0.2 5.8e-06 25.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON95802.1 - 3.9e-06 26.2 0.2 5.5e-06 25.7 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EON95802.1 - 6.4e-06 25.6 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EON95802.1 - 1.9e-05 24.2 0.2 0.0014 18.1 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EON95802.1 - 6.2e-05 22.4 0.4 0.00012 21.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EON95802.1 - 0.00013 21.4 0.1 0.00024 20.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON95802.1 - 0.00014 22.4 0.2 0.00036 21.0 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EON95802.1 - 0.00036 19.9 0.1 0.0012 18.3 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EON95802.1 - 0.0066 15.5 0.2 0.16 11.0 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.6 EON95802.1 - 0.021 14.0 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EON95802.1 - 0.028 13.1 0.1 0.044 12.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 EON95802.1 - 0.13 11.4 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ADH_N PF08240.12 EON95803.1 - 8.4e-28 96.4 2.4 1.6e-27 95.5 2.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON95803.1 - 2.9e-19 69.3 0.0 4.8e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EON95803.1 - 0.015 14.6 0.1 0.026 13.8 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain POR PF01558.18 EON95803.1 - 0.062 13.4 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase ELFV_dehydrog PF00208.21 EON95803.1 - 0.1 12.3 0.3 0.16 11.7 0.3 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_zinc_N_2 PF13602.6 EON95803.1 - 0.1 13.6 0.0 0.24 12.5 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Abhydrolase_1 PF00561.20 EON95804.1 - 3.3e-24 85.9 0.1 1e-23 84.3 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EON95804.1 - 5.2e-08 32.9 0.0 7.6e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 TAP-like protein 2-Hacid_dh_C PF02826.19 EON95805.1 - 1.9e-50 170.7 0.0 2.9e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EON95805.1 - 0.0022 18.5 0.1 0.0039 17.8 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EON95805.1 - 0.0081 16.3 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EON95805.1 - 0.043 13.4 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Gly_rich_SFCGS PF14272.6 EON95805.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Glycine-rich SFCGS Ammonium_transp PF00909.21 EON95806.1 - 2.6e-80 270.1 11.0 3e-80 269.9 11.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SepZ PF06066.11 EON95806.1 - 0.092 13.0 0.3 0.24 11.6 0.3 1.7 1 0 0 1 1 1 0 SepZ Transgly_assoc PF04226.13 EON95806.1 - 8 6.8 11.4 0.19 12.0 1.2 3.1 2 1 1 3 3 3 0 Transglycosylase associated protein Baculo_PEP_C PF04513.12 EON95807.1 - 5.8 7.0 7.8 0.25 11.4 1.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus adh_short_C2 PF13561.6 EON95808.1 - 1.3e-06 28.1 0.0 1.3e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peptidase_M14 PF00246.24 EON95809.1 - 5.7e-59 200.3 0.0 2.7e-32 112.7 0.0 2.4 3 0 0 3 3 3 2 Zinc carboxypeptidase Propep_M14 PF02244.16 EON95809.1 - 0.073 13.5 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Isochorismatase PF00857.20 EON95810.1 - 3.5e-10 40.3 0.0 1.6e-08 34.9 0.0 2.6 2 1 0 2 2 2 1 Isochorismatase family Arginase PF00491.21 EON95811.1 - 6.9e-70 235.7 0.1 7.6e-70 235.6 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EON95811.1 - 0.089 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain p450 PF00067.22 EON95812.1 - 1.3e-75 254.9 0.0 1.6e-75 254.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Corona_S1 PF01600.16 EON95812.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Coronavirus S1 glycoprotein NmrA PF05368.13 EON95813.1 - 1.5e-21 77.1 0.0 1.7e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EON95813.1 - 1e-06 28.8 0.0 1.6e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Pribosyltran PF00156.27 EON95814.1 - 9.6e-18 64.2 0.9 1.3e-17 63.7 0.9 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Holin_9 PF16936.5 EON95814.1 - 0.027 14.6 6.4 1.3 9.2 2.8 2.9 2 1 1 3 3 3 0 Putative holin UPRTase PF14681.6 EON95814.1 - 0.034 13.6 0.1 0.1 12.0 0.1 1.8 1 1 0 1 1 1 0 Uracil phosphoribosyltransferase ADH_zinc_N PF00107.26 EON95814.1 - 0.064 13.2 0.0 0.094 12.7 0.0 1.4 1 1 0 1 1 1 0 Zinc-binding dehydrogenase PS-DH PF14765.6 EON95815.1 - 1.1e-63 215.2 0.0 1.6e-63 214.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EON95815.1 - 7e-57 192.2 0.1 3.7e-56 189.9 0.0 2.2 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EON95815.1 - 1.8e-56 192.0 0.0 2.9e-56 191.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EON95815.1 - 9.5e-36 122.4 0.1 2.2e-35 121.2 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EON95815.1 - 2.2e-25 89.3 0.0 5e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EON95815.1 - 2.7e-16 60.1 0.0 8.7e-16 58.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EON95815.1 - 1.9e-15 57.0 0.0 6.5e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON95815.1 - 4.7e-15 56.8 0.0 2.1e-13 51.5 0.0 3.1 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EON95815.1 - 1.1e-11 44.9 0.0 2.9e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON95815.1 - 6e-10 39.7 0.0 2e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EON95815.1 - 3e-08 33.4 0.0 8e-07 28.7 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_11 PF08241.12 EON95815.1 - 1.6e-07 31.9 0.0 6.6e-07 29.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ketoacyl-synt PF00109.26 EON95815.1 - 6.4e-07 29.2 0.0 1.5e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_31 PF13847.6 EON95815.1 - 1.3e-06 28.3 0.0 3.1e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EON95815.1 - 2.1e-06 28.0 0.1 6.9e-06 26.3 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EON95815.1 - 6.1e-06 26.1 0.1 1.6e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 EON95815.1 - 0.00017 21.3 0.0 0.00088 18.9 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase SAT PF16073.5 EON95815.1 - 0.011 15.5 0.0 0.045 13.5 0.0 1.9 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Ubie_methyltran PF01209.18 EON95815.1 - 0.11 11.7 0.0 0.36 10.1 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Phage_tail_2 PF06199.11 EON95817.1 - 0.038 14.1 0.1 0.05 13.7 0.1 1.2 1 0 0 1 1 1 0 Phage tail tube protein Acyl_transf_3 PF01757.22 EON95818.1 - 5.5e-30 104.6 13.7 7.6e-30 104.1 13.7 1.3 1 0 0 1 1 1 1 Acyltransferase family DUF5134 PF17197.4 EON95818.1 - 0.011 15.7 0.9 0.041 13.8 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) DUF418 PF04235.12 EON95818.1 - 0.035 14.0 0.4 0.035 14.0 0.4 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF418) PGPGW PF09656.10 EON95818.1 - 0.07 12.7 1.0 0.25 10.9 0.1 2.4 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) Aldo_ket_red PF00248.21 EON95819.1 - 1.2e-59 201.9 0.0 1.6e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Metal_resist PF13801.6 EON95819.1 - 0.086 13.0 0.2 0.17 12.1 0.2 1.4 1 0 0 1 1 1 0 Heavy-metal resistance WSC PF01822.19 EON95820.1 - 5.2e-11 42.6 6.1 1.9e-10 40.8 6.1 2.1 1 0 0 1 1 1 1 WSC domain Ribonuc_L-PSP PF01042.21 EON95821.1 - 2.1e-17 63.3 0.0 2.6e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP NOGCT PF08155.11 EON95821.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 NOGCT (NUC087) domain ADH_N PF08240.12 EON95822.1 - 6.6e-16 58.1 0.1 3.5e-15 55.8 0.1 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON95822.1 - 3e-08 33.7 1.5 1.6e-07 31.3 0.1 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EON95822.1 - 0.0025 17.3 0.1 0.012 15.1 0.0 1.9 1 1 1 2 2 2 1 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 EON95822.1 - 0.073 12.1 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 EON95822.1 - 0.077 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EON95822.1 - 0.17 10.6 0.0 0.26 9.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein CRAL_TRIO_N PF03765.15 EON95823.1 - 4.5e-06 26.8 0.0 9.5e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.20 EON95823.1 - 5.6e-05 22.9 0.1 0.00019 21.2 0.0 1.8 1 1 1 2 2 2 1 CRAL/TRIO domain DMA PF03474.14 EON95823.1 - 0.15 11.7 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 DMRTA motif Dioxygenase_C PF00775.21 EON95824.1 - 1.6e-09 37.5 0.0 2.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Pkinase PF00069.25 EON95825.1 - 5.8e-74 248.8 0.0 8.8e-74 248.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON95825.1 - 8.3e-38 130.1 0.0 2e-37 128.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EON95825.1 - 0.00026 20.4 0.6 0.54 9.5 0.0 2.7 2 1 0 3 3 3 2 Kinase-like Haspin_kinase PF12330.8 EON95825.1 - 0.00055 19.0 0.0 0.00081 18.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EON95825.1 - 0.02 13.7 2.4 0.025 13.4 0.0 2.2 3 0 0 3 3 3 0 Fungal protein kinase APH PF01636.23 EON95825.1 - 0.023 14.6 0.1 0.091 12.7 0.1 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family Amidohydro_3 PF07969.11 EON95826.1 - 1.5e-53 183.0 0.4 1.7e-53 182.8 0.4 1.0 1 0 0 1 1 1 1 Amidohydrolase family DUF4129 PF13559.6 EON95826.1 - 0.68 10.2 3.5 17 5.8 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4129) adh_short PF00106.25 EON95827.1 - 1.4e-36 125.8 0.1 1.7e-36 125.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON95827.1 - 7.8e-27 94.3 0.0 1.4e-26 93.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON95827.1 - 5.1e-13 49.3 0.0 7e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON95827.1 - 1.2e-05 25.0 0.1 4.5e-05 23.0 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EON95827.1 - 5.6e-05 22.4 0.0 7.7e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EON95827.1 - 0.012 15.1 0.1 0.021 14.2 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 EON95827.1 - 0.025 13.9 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) p450 PF00067.22 EON95828.1 - 5.1e-30 104.6 0.0 6.2e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 JAB PF01398.21 EON95829.1 - 1.6e-32 112.0 0.0 2.7e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EON95829.1 - 5.4e-12 46.1 0.6 1e-11 45.2 0.6 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EON95829.1 - 2.2e-07 30.7 0.0 3.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Sugar_tr PF00083.24 EON95830.1 - 9.4e-72 242.3 21.5 1.1e-71 242.1 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON95830.1 - 4.8e-17 61.9 30.2 3.7e-15 55.7 26.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RNase_PH PF01138.21 EON95831.1 - 7.4e-34 117.1 0.2 1.1e-33 116.6 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EON95831.1 - 0.0043 17.1 0.1 0.0084 16.1 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Hist_deacetyl PF00850.19 EON95833.1 - 1.7e-79 267.5 0.1 3.7e-79 266.4 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain Fungal_trans PF04082.18 EON95834.1 - 6.4e-19 68.0 0.6 8.1e-19 67.7 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Suv3_N PF18114.1 EON95834.1 - 0.078 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Suv3 helical N-terminal domain VCBS PF13517.6 EON95836.1 - 2.1e-27 95.5 41.6 6e-12 46.0 1.8 7.9 3 2 4 8 8 8 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 EON95836.1 - 4.5e-05 22.9 8.6 0.4 10.0 0.1 5.8 3 2 3 6 6 6 3 Insecticide toxin TcdB middle/N-terminal region Chitin_bind_1 PF00187.19 EON95836.1 - 0.00019 21.8 14.5 0.00068 20.1 14.5 2.0 1 0 0 1 1 1 1 Chitin recognition protein FG-GAP PF01839.23 EON95836.1 - 0.069 13.3 23.7 0.91 9.7 1.2 5.6 5 0 0 5 5 5 0 FG-GAP repeat COesterase PF00135.28 EON95837.1 - 1.2e-67 229.0 0.3 1.8e-67 228.4 0.3 1.1 1 0 0 1 1 1 1 Carboxylesterase family DUF423 PF04241.15 EON95837.1 - 2.5e-20 72.4 0.2 2.5e-20 72.4 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF423) Abhydrolase_3 PF07859.13 EON95837.1 - 1.4e-12 48.0 0.1 5.3e-12 46.0 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EON95837.1 - 0.0021 17.6 0.7 0.0039 16.7 0.7 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Thioredoxin PF00085.20 EON95838.1 - 3.8e-30 103.9 0.0 1.9e-24 85.6 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 EON95838.1 - 2.7e-06 27.0 0.0 0.00023 20.6 0.0 2.9 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EON95838.1 - 3.9e-05 24.1 0.4 0.03 14.8 0.4 2.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EON95838.1 - 0.003 17.9 0.0 0.54 10.6 0.0 3.1 3 1 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 EON95838.1 - 0.0037 17.2 0.1 0.042 13.8 0.0 2.3 2 0 0 2 2 2 1 AhpC/TSA family ERp29_N PF07912.13 EON95838.1 - 0.0083 16.3 0.0 0.041 14.0 0.0 2.0 2 0 0 2 2 2 1 ERp29, N-terminal domain Thioredoxin_7 PF13899.6 EON95838.1 - 0.013 15.6 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like QSOX_Trx1 PF18108.1 EON95838.1 - 0.07 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 QSOX Trx-like domain CP12 PF02672.15 EON95838.1 - 0.076 13.8 0.3 1.3 9.8 0.0 2.8 2 0 0 2 2 2 0 CP12 domain CCDC53 PF10152.9 EON95838.1 - 0.14 12.6 8.2 0.14 12.6 0.7 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TraF PF13728.6 EON95838.1 - 0.32 10.8 0.0 0.32 10.8 0.0 3.8 4 0 0 4 4 4 0 F plasmid transfer operon protein NAD_binding_10 PF13460.6 EON95839.1 - 0.017 15.0 0.0 0.041 13.8 0.0 1.6 1 1 1 2 2 2 0 NAD(P)H-binding NAD_binding_4 PF07993.12 EON95839.1 - 0.041 13.0 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein DUF1120 PF06551.12 EON95839.1 - 0.092 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) DXP_reductoisom PF02670.16 EON95839.1 - 0.14 12.8 0.1 0.19 12.4 0.1 1.4 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase MFS_1 PF07690.16 EON95840.1 - 6e-16 58.3 42.3 1.6e-15 56.9 41.2 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Transp_cyt_pur PF02133.15 EON95841.1 - 4.2e-30 104.9 5.7 4.9e-30 104.7 5.7 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CTV_P6 PF06706.11 EON95841.1 - 1.2 8.9 6.7 1.1 9.0 1.4 2.5 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein WD40 PF00400.32 EON95843.1 - 2.5e-09 37.6 10.7 3.4e-05 24.5 0.3 5.6 6 1 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON95843.1 - 2.9e-06 27.5 0.1 0.0034 17.7 0.1 3.9 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Rib PF08428.10 EON95843.1 - 0.12 12.4 0.1 0.33 11.0 0.1 1.7 1 0 0 1 1 1 0 Rib/alpha-like repeat MFS_1 PF07690.16 EON95844.1 - 7.7e-05 21.8 22.2 0.00043 19.3 22.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EON95844.1 - 0.42 9.4 7.0 3.7 6.3 0.3 2.8 3 0 0 3 3 3 0 MFS_1 like family Vta1 PF04652.16 EON95845.1 - 2.1e-55 186.7 1.2 2.5e-55 186.4 1.2 1.1 1 0 0 1 1 1 1 Vta1 like adh_short PF00106.25 EON95847.1 - 8e-30 103.7 0.0 1e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON95847.1 - 1.3e-26 93.7 0.1 2.4e-25 89.4 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON95847.1 - 4.1e-06 26.8 0.0 7.6e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 KR domain TerD PF02342.18 EON95847.1 - 0.14 11.6 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 TerD domain Pkinase PF00069.25 EON95849.1 - 1.5e-24 86.8 0.0 7.9e-23 81.1 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON95849.1 - 1.7e-10 40.6 0.0 0.00022 20.6 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase adh_short_C2 PF13561.6 EON95851.1 - 6.2e-50 169.9 0.2 7.5e-50 169.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON95851.1 - 1.7e-41 141.8 0.0 2.1e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON95851.1 - 4e-14 52.9 0.2 5.6e-14 52.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON95851.1 - 0.0043 16.6 0.0 0.0059 16.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF134 PF02001.16 EON95851.1 - 0.023 15.2 0.5 9.1 6.9 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function DUF134 DIOX_N PF14226.6 EON95852.1 - 7.9e-30 104.0 0.0 1.1e-29 103.5 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Epimerase PF01370.21 EON95853.1 - 3.7e-16 59.3 0.0 5.9e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EON95853.1 - 3.5e-10 39.4 0.0 4.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EON95853.1 - 2.2e-09 36.9 0.0 3.9e-07 29.5 0.1 2.6 2 1 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EON95853.1 - 5.9e-09 35.8 0.1 2e-08 34.1 0.1 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EON95853.1 - 5.7e-08 32.9 0.0 1e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 EON95853.1 - 1.4e-05 25.1 0.0 2.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EON95853.1 - 0.00061 19.0 0.0 0.00083 18.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EON95853.1 - 0.0019 17.7 0.0 0.0036 16.8 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 EON95853.1 - 0.005 16.4 0.9 0.016 14.7 0.4 2.1 2 1 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 EON95853.1 - 0.024 13.7 0.0 0.055 12.6 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain OPT PF03169.15 EON95854.1 - 1.4e-84 284.9 45.5 1.6e-84 284.7 45.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Menin PF05053.13 EON95854.1 - 0.28 9.5 0.1 0.43 8.9 0.1 1.2 1 0 0 1 1 1 0 Menin Peptidase_M14 PF00246.24 EON95855.1 - 1.5e-39 136.5 1.1 2.2e-39 136.0 1.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase MFS_1 PF07690.16 EON95857.1 - 2.1e-19 69.7 64.9 7.5e-13 48.1 37.9 2.9 1 1 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 EON95858.1 - 8.6e-35 120.4 0.0 1.2e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON95858.1 - 3e-18 66.0 0.0 7e-18 64.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EON95858.1 - 9.4e-05 21.9 0.0 0.00022 20.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 EON95858.1 - 0.17 11.4 0.1 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase GRDP-like PF07173.12 EON95860.1 - 1.7e-15 57.9 2.2 4.6e-12 46.8 0.0 2.9 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like PhnA_Zn_Ribbon PF08274.12 EON95860.1 - 0.068 13.1 0.1 0.6 10.1 0.0 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-CSL PF05207.13 EON95860.1 - 0.16 11.7 0.2 20 5.0 0.0 2.4 2 0 0 2 2 2 0 CSL zinc finger FAD_binding_4 PF01565.23 EON95861.1 - 6e-22 77.9 0.9 9.1e-22 77.3 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_C PF05199.13 EON95862.1 - 8.5e-26 91.2 0.0 1.1e-25 90.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EON95862.1 - 1.1e-05 25.0 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase HHH_5 PF14520.6 EON95862.1 - 0.05 14.2 0.1 9.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain PDR_CDR PF06422.12 EON95863.1 - 3.1e-31 107.1 0.0 5.9e-31 106.2 0.0 1.4 1 0 0 1 1 1 1 CDR ABC transporter ABC_tran PF00005.27 EON95863.1 - 1.9e-17 64.0 0.0 2.9e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON95863.1 - 5.2e-05 23.2 0.0 0.24 11.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EON95863.1 - 6.9e-05 22.5 0.0 0.00027 20.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EON95863.1 - 0.0002 21.3 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane PF01061.24 EON95863.1 - 0.00048 19.6 1.2 0.00091 18.7 0.4 1.7 2 0 0 2 2 2 1 ABC-2 type transporter AAA_33 PF13671.6 EON95863.1 - 0.0008 19.6 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EON95863.1 - 0.00081 19.9 0.0 0.0018 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EON95863.1 - 0.001 18.5 0.0 0.053 13.0 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EON95863.1 - 0.001 19.4 0.3 0.0019 18.6 0.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EON95863.1 - 0.0035 17.0 0.2 0.007 16.1 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.6 EON95863.1 - 0.059 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EON95863.1 - 0.077 12.6 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EON95863.1 - 0.084 13.4 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EON95863.1 - 0.16 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Acetyltransf_3 PF13302.7 EON95864.1 - 3.4e-13 50.5 0.0 4.8e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON95864.1 - 1.6e-10 41.2 0.0 2.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON95864.1 - 0.00015 22.1 0.0 0.00025 21.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EON95864.1 - 0.029 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FMN_red PF03358.15 EON95865.1 - 3.9e-32 111.2 0.0 5.1e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EON95865.1 - 1.2e-08 34.9 0.0 1.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Methyltransf_2 PF00891.18 EON95867.1 - 2e-18 66.5 0.0 3.5e-18 65.7 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain NIF PF03031.18 EON95868.1 - 1e-38 132.5 0.0 1.5e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Neuromodulin_N PF10580.9 EON95868.1 - 0.12 12.2 1.4 0.25 11.2 1.4 1.5 1 0 0 1 1 1 0 Gap junction protein N-terminal region PMSR PF01625.21 EON95870.1 - 1.5e-62 210.3 1.7 1.8e-62 210.0 1.7 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Sugar_tr PF00083.24 EON95871.1 - 1.8e-83 281.0 15.5 2.1e-83 280.7 15.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON95871.1 - 1.7e-32 112.8 42.5 2.2e-29 102.5 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 EON95871.1 - 0.36 11.4 4.7 1.1 9.9 4.7 1.9 1 0 0 1 1 1 0 Phage holin family 2 Pro_dh PF01619.18 EON95872.1 - 3.4e-69 233.6 0.0 4e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Proline dehydrogenase SnoaL PF07366.12 EON95873.1 - 4.9e-12 45.7 0.0 9.7e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EON95873.1 - 4.7e-06 27.2 0.1 1.9e-05 25.3 0.1 2.0 1 0 0 1 1 1 1 SnoaL-like domain TEX29 PF15839.5 EON95874.1 - 0.13 12.8 0.0 0.38 11.4 0.0 1.8 1 0 0 1 1 1 0 Testis-expressed sequence 29 protein DUF3792 PF12670.7 EON95874.1 - 0.34 11.1 9.0 0.27 11.4 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Sugar_tr PF00083.24 EON95875.1 - 7.3e-96 321.8 25.5 8.6e-96 321.5 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON95875.1 - 6.8e-19 68.0 53.2 2.6e-18 66.1 27.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 EON95875.1 - 0.0065 16.3 3.1 1.4 8.6 0.2 2.8 3 0 0 3 3 3 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LapA_dom PF06305.11 EON95875.1 - 0.32 10.8 4.6 5.7 6.8 0.2 3.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Phage_holin_3_2 PF04550.12 EON95875.1 - 2.9 8.5 9.1 0.79 10.3 1.8 3.7 3 1 0 3 3 3 0 Phage holin family 2 MFS_1 PF07690.16 EON95876.1 - 9.6e-41 139.9 27.4 9.6e-41 139.9 27.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON95876.1 - 5.8e-15 55.1 18.2 9.5e-15 54.4 18.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MatE PF01554.18 EON95877.1 - 8.8e-49 165.3 34.7 8.5e-36 123.0 10.4 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EON95877.1 - 0.0029 17.7 12.1 0.0029 17.7 12.1 4.0 2 1 1 3 3 3 1 Polysaccharide biosynthesis C-terminal domain DUF5389 PF17364.2 EON95877.1 - 0.063 13.3 1.4 0.17 12.0 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5389) Bax1-I PF01027.20 EON95878.1 - 1.6e-34 119.6 13.0 4.7e-34 118.0 9.9 2.0 2 0 0 2 2 2 2 Inhibitor of apoptosis-promoting Bax1 MFS_1 PF07690.16 EON95881.1 - 1.9e-11 43.5 12.2 2.2e-11 43.3 12.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON95881.1 - 3.8e-08 32.6 0.0 4.2e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Cactin_mid PF10312.9 EON95882.1 - 3e-65 219.7 7.4 4.5e-65 219.1 7.4 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 EON95882.1 - 3.4e-58 195.0 5.6 6.1e-58 194.2 5.6 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF1087 PF06465.13 EON95882.1 - 0.0099 15.9 5.0 0.071 13.2 0.6 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1087) SF3A2 PF16835.5 EON95882.1 - 0.033 14.5 0.0 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) MFS_1 PF07690.16 EON95883.1 - 5.9e-09 35.3 6.4 4.3e-08 32.5 2.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PALP PF00291.25 EON95884.1 - 4.6e-42 144.4 0.2 5.5e-42 144.2 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Sugar_tr PF00083.24 EON95885.1 - 8.8e-57 192.9 4.3 1.1e-56 192.6 4.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON95885.1 - 1e-11 44.4 9.6 1e-11 44.4 9.6 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Phage_CP76 PF06892.11 EON95885.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) Glyco_hydro_28 PF00295.17 EON95886.1 - 5.2e-50 170.4 6.2 8e-50 169.7 6.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 RPE65 PF03055.15 EON95887.1 - 3.8e-96 323.1 0.0 4.6e-96 322.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein GFO_IDH_MocA PF01408.22 EON95888.1 - 7.7e-18 65.5 0.1 1.4e-17 64.6 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EON95888.1 - 0.02 15.6 0.0 0.054 14.2 0.1 1.7 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EON95888.1 - 0.036 14.6 0.0 0.11 13.1 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_25 PF13649.6 EON95888.1 - 0.071 13.8 0.0 0.15 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Aldo_ket_red PF00248.21 EON95889.1 - 9e-61 205.6 0.0 1.1e-60 205.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 EON95891.1 - 2.4e-15 56.3 0.0 3.6e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EON95892.1 - 2.1e-20 73.0 19.4 1.7e-13 50.3 12.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_5_1 PF06946.11 EON95892.1 - 4.7 7.7 8.6 2.3 8.6 0.7 2.4 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 Bac_rhamnosid6H PF17389.2 EON95893.1 - 3.1e-74 250.3 0.0 3.7e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 EON95893.1 - 8e-25 86.4 0.0 1.5e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain cNMP_binding PF00027.29 EON95894.1 - 3e-35 120.2 0.0 3.9e-18 65.3 0.0 2.5 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain cNMPbd_u2 PF16643.5 EON95894.1 - 0.054 14.0 1.1 0.067 13.6 0.1 1.7 2 0 0 2 2 2 0 Unstructured region on cNMP-binding protein Sugar_tr PF00083.24 EON95895.1 - 7.7e-117 390.9 22.7 8.8e-117 390.7 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON95895.1 - 6.6e-25 87.8 29.7 1.8e-16 60.0 7.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily AA_permease_2 PF13520.6 EON95896.1 - 1.8e-62 211.6 56.2 2.2e-62 211.3 56.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EON95896.1 - 3.3e-25 88.6 48.5 4.6e-25 88.2 48.5 1.1 1 0 0 1 1 1 1 Amino acid permease ADH_zinc_N PF00107.26 EON95897.1 - 4.4e-16 59.0 0.0 8.2e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON95897.1 - 1.8e-13 51.7 0.0 2.6e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EON95897.1 - 8.9e-05 22.1 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N PF08240.12 EON95897.1 - 0.0017 18.2 0.2 0.13 12.1 0.0 2.7 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain CGI-121 PF08617.10 EON95898.1 - 6.8e-50 169.3 0.0 7.8e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Zeta_toxin PF06414.12 EON95898.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin VPS38 PF17649.1 EON95899.1 - 4.8e-13 48.8 0.3 1.6e-09 37.2 0.1 3.1 3 0 0 3 3 3 2 Vacuolar protein sorting 38 Atg14 PF10186.9 EON95899.1 - 1.2e-12 47.6 11.1 4.8e-09 35.7 0.0 2.5 3 0 0 3 3 3 2 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2630 PF10944.8 EON95899.1 - 0.26 11.7 5.0 0.59 10.6 5.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Sugar_tr PF00083.24 EON95900.1 - 2.2e-59 201.5 27.0 2.6e-59 201.3 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON95900.1 - 1.1e-12 47.6 38.3 5.6e-12 45.3 34.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_7 PF03441.14 EON95901.1 - 1.2e-83 279.6 0.6 2.2e-83 278.7 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EON95901.1 - 3.3e-39 134.5 0.0 5.4e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.26 EON95901.1 - 0.038 14.5 0.0 0.098 13.2 0.0 1.7 1 0 0 1 1 1 0 Universal stress protein family Tim17 PF02466.19 EON95902.1 - 0.00067 20.0 1.5 0.0011 19.3 1.5 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TRI12 PF06609.13 EON95903.1 - 1.1e-21 77.0 4.6 1.3e-21 76.7 4.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EON95904.1 - 1.4e-10 40.7 17.3 1.7e-10 40.4 17.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EON95904.1 - 0.00068 18.6 7.4 0.00096 18.1 7.4 1.1 1 0 0 1 1 1 1 MFS_1 like family Zn_clus PF00172.18 EON95905.1 - 2.7e-09 37.0 11.2 4.1e-09 36.4 11.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DivIC PF04977.15 EON95905.1 - 0.23 11.2 0.2 0.54 10.1 0.2 1.5 1 0 0 1 1 1 0 Septum formation initiator RAP1 PF07218.11 EON95905.1 - 0.32 9.2 3.4 0.42 8.9 3.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Aldedh PF00171.22 EON95906.1 - 1.1e-118 396.7 0.0 1.2e-118 396.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.16 EON95907.1 - 9.3e-31 107.0 24.5 9.3e-31 107.0 24.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Nucleopor_Nup85 PF07575.13 EON95907.1 - 0.22 10.0 0.4 0.33 9.5 0.4 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin PhaG_MnhG_YufB PF03334.14 EON95907.1 - 0.28 11.4 4.1 19 5.6 0.0 3.5 2 1 1 3 3 3 0 Na+/H+ antiporter subunit Ribosomal_S21e PF01249.18 EON95908.1 - 6.2e-42 141.6 0.1 6.9e-42 141.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e p450 PF00067.22 EON95909.1 - 2.3e-52 178.3 0.0 7.2e-46 156.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Med31 PF05669.12 EON95910.1 - 2.5e-37 126.8 3.8 3.1e-37 126.5 3.8 1.0 1 0 0 1 1 1 1 SOH1 T3SSipB PF16535.5 EON95911.1 - 0.95 9.9 9.9 0.037 14.5 2.6 2.4 2 1 0 2 2 2 0 Type III cell invasion protein SipB Fez1 PF06818.15 EON95911.1 - 6.4 7.2 23.9 15 5.9 16.6 2.9 1 1 1 2 2 2 0 Fez1 TPR_MLP1_2 PF07926.12 EON95912.1 - 0.0032 17.5 46.3 0.32 11.1 19.6 3.4 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein ERM PF00769.19 EON95912.1 - 0.0043 16.9 17.1 0.0043 16.9 17.1 2.5 2 1 0 2 2 2 2 Ezrin/radixin/moesin family Bacillus_HBL PF05791.11 EON95912.1 - 0.063 13.1 16.2 0.21 11.4 6.2 2.7 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF3584 PF12128.8 EON95912.1 - 0.16 9.5 33.4 0.19 9.2 33.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Vac_Fusion PF02346.16 EON95912.1 - 0.56 9.9 3.8 43 3.8 0.0 4.1 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 GAS PF13851.6 EON95912.1 - 1 8.6 33.5 0.016 14.6 13.1 2.6 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 EON95912.1 - 1.2 8.6 34.1 1.3 8.5 19.7 3.0 2 1 1 3 3 3 0 Intermediate filament protein Jnk-SapK_ap_N PF09744.9 EON95912.1 - 1.6 8.9 38.9 0.74 10.0 13.8 3.8 1 1 2 4 4 4 0 JNK_SAPK-associated protein-1 Histidinol_dh PF00815.20 EON95912.1 - 3.8 6.4 7.6 2.5 7.0 0.2 2.2 2 0 0 2 2 2 0 Histidinol dehydrogenase DUF3450 PF11932.8 EON95912.1 - 4.8 6.4 33.6 1.7 7.9 16.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 EON95912.1 - 9 5.5 34.1 1.8e+04 -5.5 34.1 2.6 1 1 0 1 1 0 0 Domain of unknown function (DUF4407) RTC PF01137.21 EON95913.1 - 8.3e-41 139.6 0.0 2.7e-40 137.9 0.0 1.8 2 1 0 2 2 2 1 RNA 3'-terminal phosphate cyclase DUF3754 PF12576.8 EON95913.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) adh_short PF00106.25 EON95914.1 - 1.8e-12 47.1 0.0 2.7e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON95914.1 - 2.2e-06 27.4 0.0 0.00014 21.5 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.19 EON95914.1 - 0.2 11.0 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Myosin_head PF00063.21 EON95916.1 - 3.4e-266 884.8 0.0 7.6e-266 883.7 0.0 1.6 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 EON95916.1 - 6.4e-13 48.3 0.1 1.7e-12 46.9 0.1 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 EON95916.1 - 1.8e-12 46.0 264.7 7.1e-09 34.1 176.3 7.6 1 1 1 3 3 3 2 Myosin tail AAA_22 PF13401.6 EON95916.1 - 0.14 12.4 0.0 0.14 12.4 0.0 5.6 6 1 0 6 6 6 0 AAA domain ComZ PF10815.8 EON95917.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 ComZ NAT PF04768.13 EON95918.1 - 1e-52 178.2 0.2 2.9e-52 176.8 0.1 1.8 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 EON95918.1 - 6.4e-30 104.1 0.0 3.3e-29 101.8 0.0 2.3 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 EON95918.1 - 7.6e-29 101.0 0.0 3.2e-28 99.0 0.0 1.9 2 0 0 2 2 2 1 Amino acid kinase family Hexokinase_2 PF03727.16 EON95919.1 - 2.4e-75 253.1 0.0 3.2e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EON95919.1 - 4.9e-74 248.5 0.0 7.8e-74 247.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Metallophos PF00149.28 EON95920.1 - 1.1e-11 45.7 0.2 1.6e-11 45.1 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EON95920.1 - 2.6e-09 37.5 0.3 3.8e-07 30.4 0.1 3.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_A22B PF04258.13 EON95921.1 - 2e-59 201.5 5.4 9.1e-40 137.0 0.6 2.1 2 0 0 2 2 2 2 Signal peptide peptidase Pro-kuma_activ PF09286.11 EON95925.1 - 5.3e-47 159.7 1.4 9.7e-47 158.8 0.9 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EON95925.1 - 0.00015 21.2 4.0 0.00032 20.1 4.0 1.5 1 0 0 1 1 1 1 Subtilase family QRPTase_C PF01729.19 EON95926.1 - 8.5e-55 185.1 0.1 1e-54 184.8 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EON95926.1 - 1.4e-17 63.5 0.0 8.8e-17 61.0 0.0 2.3 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain KDGP_aldolase PF07071.11 EON95926.1 - 0.013 15.3 0.6 0.028 14.2 0.1 1.9 3 0 0 3 3 3 0 KDGP aldolase IGPS PF00218.21 EON95926.1 - 0.098 11.8 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase 4HBT_3 PF13622.6 EON95927.1 - 1.1e-53 183.0 0.5 1.4e-53 182.7 0.5 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EON95927.1 - 2.9e-11 43.3 0.0 9.4e-05 22.3 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase Thaumatin PF00314.17 EON95928.1 - 6.2e-59 199.2 3.7 7.8e-59 198.9 3.7 1.1 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 EON95928.1 - 0.04 13.2 0.1 6 6.0 0.0 2.2 2 0 0 2 2 2 0 Beta-1,3-glucanase B_lectin PF01453.24 EON95929.1 - 0.093 13.3 0.0 0.37 11.3 0.0 2.0 1 1 1 2 2 2 0 D-mannose binding lectin RSF PF14876.6 EON95929.1 - 0.093 11.7 0.1 0.35 9.8 0.0 1.8 1 1 1 2 2 2 0 Respiratory growth transcriptional regulator adh_short PF00106.25 EON95930.1 - 1.8e-14 53.7 0.0 2e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON95930.1 - 1.5e-08 34.5 0.1 1.3e-07 31.4 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON95930.1 - 6.2e-06 26.2 0.1 9.2e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Oxysterol_BP PF01237.18 EON95931.1 - 7.6e-134 446.2 0.1 4.1e-133 443.8 0.0 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.7 EON95931.1 - 4.9e-19 68.7 0.0 7.2e-09 36.1 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EON95931.1 - 5.9e-17 61.5 0.3 4.5e-10 39.6 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EON95931.1 - 6.3e-16 58.0 0.4 2.7e-05 24.4 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EON95931.1 - 3.5e-14 52.9 0.1 6.7e-08 32.9 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EON95931.1 - 1.3e-12 46.7 0.1 0.0011 19.3 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.29 EON95931.1 - 1.8e-12 47.7 0.9 4.5e-12 46.4 0.9 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EON95931.1 - 6.5e-08 32.7 0.6 1.5e-07 31.5 0.6 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EON95931.1 - 2.5e-05 24.7 2.1 6.6e-05 23.3 2.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DndB PF14072.6 EON95931.1 - 0.045 13.0 0.2 0.089 12.0 0.2 1.4 1 0 0 1 1 1 0 DNA-sulfur modification-associated Annexin PF00191.20 EON95932.1 - 2.8e-19 68.9 0.1 2.5e-06 27.5 0.0 4.4 4 0 0 4 4 4 4 Annexin DUF5617 PF18493.1 EON95932.1 - 0.012 15.6 0.4 0.033 14.3 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) Acetyltransf_1 PF00583.25 EON95933.1 - 0.00039 20.6 0.0 0.00095 19.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON95933.1 - 0.023 15.1 0.0 0.037 14.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AIRS PF00586.24 EON95933.1 - 0.053 14.2 0.4 0.13 12.9 0.4 1.7 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain ORC6 PF05460.13 EON95934.1 - 0.16 11.2 14.4 0.25 10.6 14.4 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf_UBZ PF18439.1 EON95934.1 - 0.19 11.3 2.1 1.9 8.1 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Sgf11 PF08209.11 EON95934.1 - 1.4 8.5 7.6 0.16 11.5 3.1 1.7 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) MFS_5 PF05631.14 EON95935.1 - 8.8e-66 222.2 6.4 1.3e-65 221.7 6.4 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EON95935.1 - 2.2e-15 56.5 23.8 4.3e-15 55.5 23.8 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4337 PF14235.6 EON95935.1 - 0.024 14.8 0.2 0.066 13.3 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Ank_3 PF13606.6 EON95936.1 - 1.3e-09 37.5 0.0 0.0028 18.0 0.0 3.8 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EON95936.1 - 3.2e-07 30.8 0.0 1.5e-06 28.7 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EON95936.1 - 6.2e-06 26.7 0.0 0.00032 21.2 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EON95936.1 - 7.8e-05 23.0 0.1 0.79 10.3 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EON95936.1 - 0.00068 19.9 0.2 0.98 9.8 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Radical_SAM PF04055.21 EON95937.1 - 1.3e-13 51.7 0.0 1.9e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily TFIIE_beta PF02186.15 EON95937.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 TFIIE beta subunit core domain Pro_isomerase PF00160.21 EON95938.1 - 1.9e-55 187.5 0.0 2.1e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AMP-binding PF00501.28 EON95939.1 - 2.6e-86 289.9 0.0 3.4e-86 289.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON95939.1 - 5.2e-20 72.2 0.0 1.3e-19 71.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 EON95940.1 - 6.6e-12 45.8 3.5 0.017 16.0 0.0 5.3 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 EON95940.1 - 0.00019 20.2 0.3 0.00031 19.5 0.3 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EON95940.1 - 0.00061 20.2 0.5 0.44 11.1 0.0 4.1 3 1 1 4 4 4 1 PQQ-like domain ANAPC4_WD40 PF12894.7 EON95940.1 - 0.0031 17.8 0.1 6.6 7.1 0.0 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EON95940.1 - 0.24 10.7 0.0 1.3 8.3 0.0 2.1 2 1 0 2 2 2 0 WD40-like domain ACPS PF01648.20 EON95941.1 - 2.7e-09 37.2 0.0 4.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Synaptobrevin PF00957.21 EON95943.1 - 2.8e-33 113.6 0.9 3.1e-33 113.4 0.9 1.0 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 EON95943.1 - 0.06 14.0 0.1 0.12 13.1 0.1 1.5 1 1 0 1 1 1 0 AT-hook-containing transcription factor MCU PF04678.13 EON95943.1 - 0.07 13.2 0.0 0.082 13.0 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter ThiF PF00899.21 EON95944.1 - 2.2e-42 145.1 0.0 3.5e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EON95944.1 - 1.1e-05 25.7 0.1 2.9e-05 24.3 0.1 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 EON95944.1 - 0.007 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 EON95944.1 - 0.025 14.8 0.1 0.071 13.4 0.1 1.8 1 0 0 1 1 1 0 TrkA-N domain Melibiase_2 PF16499.5 EON95944.1 - 0.068 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha galactosidase A ApbA PF02558.16 EON95944.1 - 0.17 11.5 0.2 0.4 10.3 0.2 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA EMC1_C PF07774.13 EON95945.1 - 8.3e-78 260.9 0.0 1.6e-77 260.0 0.0 1.5 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EON95945.1 - 2.6e-25 89.4 9.3 3.7e-22 79.1 4.1 3.0 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.21 EON95945.1 - 8.8e-07 28.6 3.4 0.00049 19.9 0.0 5.5 6 0 0 6 6 6 1 PQQ enzyme repeat zf-C3H1 PF10650.9 EON95947.1 - 1.1e-09 37.9 4.2 1.9e-09 37.1 4.2 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain zf-CCCH PF00642.24 EON95947.1 - 0.0092 15.9 0.5 0.014 15.3 0.5 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4191 PF13829.6 EON95947.1 - 0.12 11.8 0.1 0.17 11.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) zf_CCCH_4 PF18345.1 EON95947.1 - 0.25 11.5 0.2 0.44 10.7 0.2 1.3 1 0 0 1 1 1 0 Zinc finger domain APG6_N PF17675.1 EON95947.1 - 1.2 9.7 6.8 3.2 8.3 6.8 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region TFIIS_C PF01096.18 EON95948.1 - 2.9e-21 75.0 2.8 2.9e-21 75.0 2.8 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EON95948.1 - 5.7e-10 38.9 3.4 1.7e-09 37.4 0.4 2.5 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit IBR PF01485.21 EON95948.1 - 0.00035 20.8 7.2 0.23 11.7 2.2 2.3 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain Baculo_LEF5_C PF11792.8 EON95948.1 - 0.072 12.8 0.5 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Desulfoferrod_N PF06397.12 EON95948.1 - 0.17 11.5 2.3 2 8.1 0.2 2.4 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-H2C2_2 PF13465.6 EON95948.1 - 0.73 10.4 12.4 1.6 9.3 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger double domain UPF0547 PF10571.9 EON95948.1 - 1.2 9.3 11.1 4.9 7.3 0.3 3.4 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zinc_ribbon_4 PF13717.6 EON95948.1 - 1.3 9.0 10.8 1.3 9.0 0.4 3.6 3 1 1 4 4 4 0 zinc-ribbon domain zf-3CxxC_2 PF17180.4 EON95948.1 - 1.5 9.6 7.1 9.9 7.0 1.1 2.5 2 1 0 2 2 2 0 Zinc-binding domain zf-RING_12 PF17976.1 EON95948.1 - 2.1 8.7 6.4 1 9.7 0.2 2.6 1 1 2 3 3 3 0 RING/Ubox like zinc-binding domain PhnA_Zn_Ribbon PF08274.12 EON95948.1 - 2.9 7.9 6.4 12 5.9 0.3 3.2 3 1 0 3 3 3 0 PhnA Zinc-Ribbon zf-ribbon_3 PF13248.6 EON95948.1 - 3.3 7.3 0.0 3.3 7.3 0.0 3.4 4 0 0 4 4 4 0 zinc-ribbon domain Gly_transf_sug PF04488.15 EON95949.1 - 1.4e-14 54.5 0.0 2.8e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif HSP70 PF00012.20 EON95950.1 - 2.4e-11 42.5 0.3 8.7e-10 37.4 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EON95950.1 - 0.023 13.5 0.1 0.14 10.9 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein CFEM PF05730.11 EON95951.1 - 1.6e-10 40.9 10.9 3e-10 40.1 10.9 1.4 1 0 0 1 1 1 1 CFEM domain RAP1 PF07218.11 EON95951.1 - 9.8 4.3 8.0 11 4.1 8.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Abhydrolase_3 PF07859.13 EON95952.1 - 9.6e-56 189.0 0.3 1.2e-55 188.6 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EON95952.1 - 3.2e-13 49.3 0.0 5.3e-13 48.6 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EON95952.1 - 9.3e-06 25.3 0.0 2.3e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 EON95952.1 - 1.1e-05 24.5 0.7 6.3e-05 22.0 0.7 1.9 1 1 0 1 1 1 1 Carboxylesterase family Thioesterase PF00975.20 EON95952.1 - 0.0019 18.4 0.1 0.007 16.5 0.1 1.9 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_2 PF02230.16 EON95952.1 - 0.0034 17.2 0.0 0.17 11.6 0.0 2.5 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 EON95952.1 - 0.024 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3844 PF12955.7 EON95954.1 - 7.6e-36 122.4 1.1 1.2e-35 121.8 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) ADAM_CR PF08516.12 EON95954.1 - 0.025 15.0 2.0 0.045 14.2 2.0 1.3 1 0 0 1 1 1 0 ADAM cysteine-rich EGF_3 PF12947.7 EON95954.1 - 0.37 11.0 7.9 0.7 10.1 7.9 1.5 1 0 0 1 1 1 0 EGF domain Zn_clus PF00172.18 EON95955.1 - 1.8e-10 40.8 12.2 3.5e-10 39.8 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EON95955.1 - 8e-05 21.8 0.2 0.00013 21.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-RRPl_C4 PF17026.5 EON95955.1 - 0.66 10.1 9.2 0.42 10.7 5.4 2.1 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type MFS_1 PF07690.16 EON95956.1 - 1.1e-34 119.9 34.1 1.4e-34 119.6 34.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EON95956.1 - 7.6e-07 28.7 22.0 2.6e-06 27.0 9.5 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Vps8 PF12816.7 EON95957.1 - 4.7e-76 254.7 0.3 4.8e-75 251.4 0.1 2.4 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EON95957.1 - 1.4e-05 25.0 0.3 0.24 11.3 0.0 3.5 3 0 0 3 3 3 2 Region in Clathrin and VPS Peptidase_M28 PF04389.17 EON95958.1 - 7.9e-38 130.1 0.0 1.2e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EON95958.1 - 2.8e-11 43.3 0.1 5.9e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EON95958.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ENTH PF01417.20 EON95959.1 - 3.4e-46 156.3 0.2 4.7e-46 155.9 0.2 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EON95959.1 - 4.7e-05 22.5 0.1 6.4e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 ANTH domain MitoNEET_N PF10660.9 EON95959.1 - 0.2 11.7 0.1 0.42 10.7 0.1 1.4 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus LSM PF01423.22 EON95960.1 - 1.6e-21 75.8 0.3 1.8e-21 75.6 0.3 1.0 1 0 0 1 1 1 1 LSM domain Sugar_tr PF00083.24 EON95961.1 - 6.1e-96 322.0 21.1 3.8e-89 299.6 15.8 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter PrpF PF04303.13 EON95961.1 - 1.1e-41 143.0 0.0 2.4e-40 138.6 0.0 2.1 2 0 0 2 2 2 1 PrpF protein MFS_1 PF07690.16 EON95961.1 - 8.2e-27 94.0 25.2 1.1e-26 93.6 24.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily SecE PF00584.20 EON95961.1 - 0.079 12.9 0.1 0.079 12.9 0.1 3.2 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex adh_short PF00106.25 EON95962.1 - 1.1e-36 126.1 0.3 1.3e-36 125.9 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON95962.1 - 7.1e-31 107.6 0.4 8.8e-31 107.3 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON95962.1 - 1.7e-08 34.6 4.5 8.5e-08 32.3 4.5 1.9 1 1 0 1 1 1 1 KR domain HI0933_like PF03486.14 EON95962.1 - 0.053 12.2 0.4 0.088 11.5 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein FMO-like PF00743.19 EON95963.1 - 1.5e-63 215.0 0.0 6e-63 213.1 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EON95963.1 - 9.9e-18 64.4 0.0 2.1e-14 53.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EON95963.1 - 1.7e-16 60.4 0.0 1.7e-13 50.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON95963.1 - 2.6e-11 43.3 0.0 7.9e-11 41.7 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EON95963.1 - 1.1e-05 25.2 0.1 1.1 8.7 0.0 3.5 3 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EON95963.1 - 0.00022 21.7 0.0 0.46 11.1 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON95963.1 - 0.00071 19.7 0.2 0.0031 17.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 EON95963.1 - 0.0028 17.7 0.1 2 8.4 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EON95963.1 - 0.0029 16.9 0.1 0.81 8.9 0.1 2.8 2 1 1 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.19 EON95963.1 - 0.0062 15.9 0.2 1 8.7 0.1 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EON95963.1 - 0.0087 16.5 0.0 2.7 8.5 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding ApbA PF02558.16 EON95963.1 - 0.012 15.3 0.0 0.53 9.9 0.0 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 EON95963.1 - 0.065 12.5 0.0 9.6 5.4 0.0 2.2 2 0 0 2 2 2 0 Thi4 family ThiF PF00899.21 EON95963.1 - 0.077 12.3 2.3 1.7 8.0 0.0 2.9 2 1 1 3 3 3 0 ThiF family Glu_dehyd_C PF16912.5 EON95963.1 - 0.096 12.2 0.3 1.8 8.0 0.0 2.7 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus IlvN PF07991.12 EON95963.1 - 0.15 11.6 0.1 8.8 5.9 0.0 3.0 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_9 PF13454.6 EON95963.1 - 0.18 11.8 2.2 37 4.3 0.2 3.5 3 1 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EON95963.1 - 0.23 10.7 0.8 0.48 9.7 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UNC-93 PF05978.16 EON95964.1 - 3e-16 59.5 9.5 8.3e-16 58.1 9.5 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EON95964.1 - 8e-15 54.6 32.2 8e-15 54.6 32.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 EON95965.1 - 1.3e-16 60.5 14.3 1.3e-16 60.5 14.3 2.3 3 0 0 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON95965.1 - 1.2e-08 34.3 1.5 1.2e-08 34.3 1.5 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter ASCH PF04266.14 EON95966.1 - 5e-09 36.7 0.0 6.6e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 ASCH domain DUF5111 PF17138.4 EON95966.1 - 0.14 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5111) PTR2 PF00854.21 EON95967.1 - 2.4e-79 267.0 7.3 3.3e-79 266.6 7.3 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EON95967.1 - 1.2e-11 44.2 22.0 8.7e-10 38.0 20.6 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily FMO-like PF00743.19 EON95968.1 - 1.2e-15 57.0 0.1 1.1e-12 47.2 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EON95968.1 - 8.6e-10 38.7 0.0 8.6e-10 38.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3Beta_HSD PF01073.19 EON95968.1 - 3.6e-08 32.7 0.0 7.2e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EON95968.1 - 1.2e-07 31.8 1.2 4e-07 30.1 0.3 2.1 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EON95968.1 - 2e-07 30.7 0.0 7.4e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EON95968.1 - 8.1e-07 28.5 0.0 1.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein K_oxygenase PF13434.6 EON95968.1 - 8.3e-07 28.4 0.0 0.00026 20.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EON95968.1 - 8.5e-07 28.5 0.0 1.5e-05 24.3 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON95968.1 - 2.2e-05 23.9 0.6 0.00015 21.1 0.1 2.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EON95968.1 - 0.0004 20.1 2.0 0.72 9.4 0.1 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase GDP_Man_Dehyd PF16363.5 EON95968.1 - 0.0091 15.4 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short_C2 PF13561.6 EON95969.1 - 2.2e-54 184.5 1.7 2.7e-54 184.2 1.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON95969.1 - 7.4e-43 146.3 3.2 9.1e-43 146.0 3.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON95969.1 - 3.8e-13 49.8 0.5 5.8e-13 49.1 0.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EON95969.1 - 0.012 15.5 0.6 0.018 14.9 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EON95969.1 - 0.017 15.2 1.9 0.11 12.5 0.7 2.3 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.21 EON95969.1 - 0.021 14.3 0.3 0.68 9.3 0.3 2.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 EON95969.1 - 0.028 14.3 0.3 0.056 13.3 0.3 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Sacchrp_dh_NADP PF03435.18 EON95969.1 - 0.052 13.8 0.1 0.096 12.9 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Cas_Cas02710 PF09670.10 EON95969.1 - 0.19 10.5 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) ADH_zinc_N PF00107.26 EON95970.1 - 3.7e-16 59.3 0.0 7.2e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON95970.1 - 8.6e-13 49.5 0.0 1.4e-12 48.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON95970.1 - 2.1e-05 24.4 0.1 0.00042 20.2 0.0 2.7 1 1 2 3 3 3 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 EON95970.1 - 0.021 14.3 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CMAS PF02353.20 EON95973.1 - 1.4e-62 211.4 0.1 1.8e-62 211.2 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EON95973.1 - 1.7e-11 44.6 0.0 3.7e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON95973.1 - 2e-10 41.2 0.0 4.3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON95973.1 - 8.1e-10 38.8 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON95973.1 - 1.7e-07 31.9 0.0 2.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON95973.1 - 2.9e-05 23.9 0.0 4.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EON95973.1 - 0.0014 18.2 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 EON95973.1 - 0.028 14.0 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 EON95973.1 - 0.032 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EON95973.1 - 0.051 13.6 0.0 0.079 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EON95973.1 - 0.051 13.3 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MARVEL PF01284.23 EON95974.1 - 3.1e-05 24.0 12.8 0.00013 22.0 11.7 2.0 1 1 1 2 2 2 1 Membrane-associating domain EBV-NA1 PF02905.14 EON95974.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain AC_N PF16214.5 EON95974.1 - 0.96 8.5 3.9 1.7 7.7 3.9 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF2070 PF09843.9 EON95974.1 - 9.6 4.4 8.3 12 4.0 8.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Beta-lactamase PF00144.24 EON95975.1 - 2.1e-30 106.1 0.6 3.2e-30 105.5 0.6 1.2 1 0 0 1 1 1 1 Beta-lactamase Acetyltransf_10 PF13673.7 EON95976.1 - 1.5e-08 34.6 0.0 2e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON95976.1 - 1.3e-06 28.7 0.0 1.6e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON95976.1 - 9.9e-06 25.9 0.0 1.4e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 EON95979.1 - 2.4e-07 30.0 25.4 2.4e-07 30.0 25.4 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EON95979.1 - 3.5e-06 26.8 2.3 3.5e-06 26.8 2.3 1.8 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 EON95979.1 - 1.8 7.3 16.6 0.021 13.7 8.1 2.0 3 0 0 3 3 3 0 Sugar (and other) transporter Sugar_tr PF00083.24 EON95980.1 - 2.3e-91 306.9 16.7 2.7e-91 306.7 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON95980.1 - 8.4e-30 103.9 12.9 8.4e-30 103.9 12.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Myelin_PLP PF01275.19 EON95980.1 - 0.043 13.7 3.9 0.12 12.3 3.9 1.7 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) DUF998 PF06197.13 EON95980.1 - 0.44 10.1 9.0 0.18 11.4 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Pro_isomerase PF00160.21 EON95981.1 - 6.2e-43 146.8 0.1 6.9e-43 146.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HMG-CoA_red PF00368.18 EON95982.1 - 2.8e-139 464.2 2.1 3.7e-139 463.8 2.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 EON95982.1 - 3.3e-51 173.2 2.5 5.6e-51 172.5 2.5 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 EON95982.1 - 4.8e-12 46.0 5.7 3e-11 43.4 5.7 2.2 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EON95982.1 - 7.2e-05 21.1 4.3 7.2e-05 21.1 4.3 1.5 2 0 0 2 2 2 1 Patched family DUF2198 PF09964.9 EON95982.1 - 0.069 13.2 0.8 0.23 11.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) fn3_5 PF06280.12 EON95983.1 - 0.036 14.8 4.3 0.17 12.6 0.0 3.2 3 0 0 3 3 3 0 Fn3-like domain Glyco_hydro_2_C PF02836.17 EON95984.1 - 2.5e-109 365.1 0.0 3.4e-109 364.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 EON95984.1 - 1.9e-53 181.6 0.0 3.5e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 EON95984.1 - 1.3e-47 161.8 0.4 2.8e-47 160.8 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 EON95984.1 - 2.1e-15 57.3 0.1 4.2e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4981 PF16353.5 EON95984.1 - 1.5e-06 28.6 0.1 5.5e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_42 PF02449.15 EON95984.1 - 0.022 14.1 0.1 0.04 13.3 0.1 1.3 1 0 0 1 1 1 0 Beta-galactosidase Sugar_tr PF00083.24 EON95985.1 - 1.7e-74 251.3 23.3 2e-74 251.1 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON95985.1 - 4.7e-22 78.4 28.9 3.6e-15 55.8 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EON95985.1 - 0.00049 18.7 1.8 0.00049 18.7 1.8 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) PEP_mutase PF13714.6 EON95986.1 - 4.4e-73 245.7 1.1 5.3e-73 245.4 1.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EON95986.1 - 0.00017 20.3 0.2 0.00033 19.3 0.2 1.5 2 0 0 2 2 2 1 Isocitrate lyase family Pantoate_transf PF02548.15 EON95986.1 - 0.0017 17.8 0.5 0.096 12.1 0.1 2.5 1 1 1 2 2 2 1 Ketopantoate hydroxymethyltransferase PucR PF07905.11 EON95986.1 - 0.032 14.5 0.0 3.1 8.1 0.0 2.4 1 1 0 2 2 2 0 Purine catabolism regulatory protein-like family Aldo_ket_red PF00248.21 EON95987.1 - 5.7e-73 245.7 0.0 6.5e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Meth_synt_2 PF01717.18 EON95988.1 - 1.8e-09 37.3 0.0 3.5e-06 26.5 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EON95988.1 - 0.0076 15.8 0.0 0.022 14.3 0.0 1.7 2 0 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain TPR_1 PF00515.28 EON95989.1 - 2.8e-41 137.7 32.7 2.7e-06 26.9 0.1 10.0 10 0 0 10 10 10 8 Tetratricopeptide repeat STI1 PF17830.1 EON95989.1 - 2e-36 123.7 11.7 1.2e-19 69.9 1.2 2.9 2 0 0 2 2 2 2 STI1 domain TPR_2 PF07719.17 EON95989.1 - 3.9e-34 114.0 33.3 1.6e-05 24.6 0.1 10.1 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 EON95989.1 - 1.8e-22 78.7 17.1 0.00045 19.9 1.0 7.7 6 1 1 7 7 7 6 TPR repeat TPR_8 PF13181.6 EON95989.1 - 4e-15 54.7 29.1 0.0004 20.4 0.2 8.4 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 EON95989.1 - 7.4e-15 55.0 12.8 1.2e-09 38.3 0.4 5.7 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EON95989.1 - 4.7e-14 52.8 15.8 0.0013 19.3 0.0 6.6 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 EON95989.1 - 1.1e-13 50.7 16.8 0.035 14.9 0.0 8.7 5 3 4 9 9 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 EON95989.1 - 6.5e-13 48.1 8.2 0.37 11.3 0.2 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 EON95989.1 - 6.6e-13 47.7 5.8 0.00045 20.0 0.0 6.4 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EON95989.1 - 2e-12 47.4 13.6 0.018 15.6 0.0 6.7 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 EON95989.1 - 7e-11 42.1 0.9 0.0004 20.5 0.1 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EON95989.1 - 1.7e-08 34.1 5.8 0.21 11.5 0.1 6.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 EON95989.1 - 0.0013 19.3 19.6 0.34 11.6 0.0 7.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EON95989.1 - 0.002 17.6 1.1 0.0039 16.6 0.0 2.0 3 0 0 3 3 3 1 MalT-like TPR region TetR_C_15 PF17918.1 EON95989.1 - 0.081 13.7 3.5 0.26 12.1 3.0 2.1 2 0 0 2 2 1 0 Tetracyclin repressor-like, C-terminal domain ANAPC3 PF12895.7 EON95989.1 - 0.18 12.0 9.9 2.3 8.5 1.6 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 EON95989.1 - 0.4 10.8 14.3 5.2 7.2 0.2 5.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF5113 PF17140.4 EON95989.1 - 0.9 9.3 10.6 1.9 8.3 0.1 3.8 4 1 1 5 5 5 0 Domain of unknown function (DUF5113) TOM20_plant PF06552.12 EON95989.1 - 1.2 8.9 5.3 2.8 7.6 0.2 3.3 3 0 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.6 EON95989.1 - 1.6 8.9 8.5 69 3.6 0.1 5.4 7 0 0 7 7 5 0 Fis1 C-terminal tetratricopeptide repeat DUF5486 PF17588.2 EON95989.1 - 1.6 8.6 6.4 4.7 7.2 1.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5486) DUF357 PF04010.13 EON95989.1 - 1.9 8.6 7.2 0.23 11.6 0.4 3.2 3 1 1 4 4 3 0 Protein of unknown function (DUF357) TPR_3 PF07720.12 EON95989.1 - 3.8 7.6 8.6 13 5.9 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat XPC-binding PF09280.11 EON95989.1 - 8.6 6.2 7.9 7.9 6.3 0.6 3.4 3 0 0 3 3 3 0 XPC-binding domain Pectate_lyase PF03211.13 EON95990.1 - 1.5e-78 263.0 13.2 1.8e-78 262.8 13.2 1.1 1 0 0 1 1 1 1 Pectate lyase AA_permease PF00324.21 EON95991.1 - 3.6e-99 332.5 38.3 4.6e-99 332.2 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON95991.1 - 3.6e-34 118.3 41.2 4.7e-34 117.9 41.2 1.2 1 0 0 1 1 1 1 Amino acid permease peroxidase PF00141.23 EON95992.1 - 1.9e-25 89.9 0.0 2.7e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Hemerythrin PF01814.23 EON95993.1 - 5.5e-08 33.5 0.9 7.3e-08 33.1 0.9 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Methyltransf_23 PF13489.6 EON95994.1 - 5.9e-12 45.7 0.0 1.9e-11 44.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Lactamase_B PF00753.27 EON95994.1 - 3.7e-07 30.4 0.6 3.6e-06 27.1 0.6 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Methyltransf_31 PF13847.6 EON95994.1 - 0.00036 20.3 0.0 0.089 12.6 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EON95994.1 - 0.00059 20.5 0.2 1.7 9.4 0.0 3.0 2 1 1 3 3 3 2 Methyltransferase domain Lactamase_B_2 PF12706.7 EON95994.1 - 0.0042 16.6 0.2 0.0071 15.9 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MTS PF05175.14 EON95994.1 - 0.16 11.5 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain 2-Hacid_dh_C PF02826.19 EON95995.1 - 6.3e-46 156.0 0.0 3.1e-45 153.7 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EON95995.1 - 4.2e-08 32.9 0.0 5.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EON95995.1 - 0.054 13.7 0.1 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase T6SS_VipA PF05591.12 EON95995.1 - 0.056 13.3 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 AOC_like PF18678.1 EON95995.1 - 0.057 13.0 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain IlvN PF07991.12 EON95995.1 - 0.07 12.7 0.2 0.24 10.9 0.1 1.8 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ras PF00071.22 EON95996.1 - 5.2e-43 146.5 0.0 8.1e-43 145.8 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EON95996.1 - 2.6e-30 105.1 0.0 3.6e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EON95996.1 - 7.9e-12 45.0 0.0 2.3e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EON95996.1 - 0.00017 21.0 0.0 0.00024 20.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EON95996.1 - 0.00069 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EON95996.1 - 0.014 15.0 0.0 0.033 13.7 0.0 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EON95996.1 - 0.037 13.5 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 EON95996.1 - 0.044 14.0 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EON95996.1 - 0.05 13.5 0.0 0.35 10.8 0.0 2.1 1 1 1 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EON95996.1 - 0.064 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EON95996.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EON95996.1 - 0.079 12.9 0.1 0.37 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EON95996.1 - 0.15 12.3 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EON95996.1 - 0.16 12.3 0.1 0.38 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EON95996.1 - 0.18 11.5 0.0 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PIG-P PF08510.12 EON95997.1 - 1.5e-53 179.9 1.0 2e-53 179.5 1.0 1.2 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 EON95997.1 - 0.081 13.2 9.5 0.13 12.6 9.5 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Phage_holin_3_6 PF07332.11 EON95997.1 - 0.22 11.6 0.7 0.31 11.1 0.7 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Rab5ip PF07019.12 EON95997.1 - 1.3 9.7 6.4 0.82 10.3 4.8 1.5 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) Glyco_hydro_3 PF00933.21 EON95998.1 - 5e-40 137.8 0.0 7.8e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EON95998.1 - 8.1e-37 127.2 0.0 1.5e-36 126.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EON95998.1 - 1.3e-18 66.9 0.1 2.3e-18 66.1 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Aldo_ket_red PF00248.21 EON96000.1 - 7.2e-65 219.1 0.0 8.7e-65 218.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mitofilin PF09731.9 EON96002.1 - 8e-157 523.8 12.9 2e-156 522.5 12.9 1.6 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Mur_ligase_M PF08245.12 EON96002.1 - 0.033 14.2 0.0 0.15 12.0 0.0 2.1 2 1 0 2 2 2 0 Mur ligase middle domain Mur_ligase_C PF02875.21 EON96002.1 - 0.049 13.9 0.4 0.49 10.7 0.0 2.9 4 0 0 4 4 4 0 Mur ligase family, glutamate ligase domain WXG100 PF06013.12 EON96002.1 - 0.52 10.6 3.1 2.8 8.2 0.8 3.3 2 1 1 3 3 3 0 Proteins of 100 residues with WXG HsbA PF12296.8 EON96002.1 - 0.66 10.4 3.9 6.1 7.3 0.2 3.5 3 0 0 3 3 3 0 Hydrophobic surface binding protein A DUF2362 PF10154.9 EON96002.1 - 0.77 8.6 4.8 1.2 8.0 4.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Apolipoprotein PF01442.18 EON96002.1 - 1.3 8.9 15.4 3.5 7.5 15.4 1.7 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain MFS_1 PF07690.16 EON96003.1 - 2.5e-44 151.6 57.6 7e-43 146.9 57.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EON96003.1 - 8e-19 67.5 19.9 1.1e-18 67.0 19.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EON96003.1 - 4.3e-15 55.5 9.1 4.3e-15 55.5 9.1 3.4 2 1 1 3 3 3 2 Sugar (and other) transporter DUF5378 PF17349.2 EON96003.1 - 0.011 15.1 1.2 0.026 13.9 1.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Fungal_trans_2 PF11951.8 EON96004.1 - 1.5e-56 191.9 0.8 2.8e-56 191.0 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EON96004.1 - 6.5e-07 29.4 4.6 1.1e-06 28.6 4.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FerA PF08165.11 EON96004.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 FerA (NUC095) domain Podoplanin PF05808.11 EON96005.1 - 7.4e-05 22.9 0.1 0.00011 22.3 0.1 1.3 1 0 0 1 1 1 1 Podoplanin Amnionless PF14828.6 EON96005.1 - 0.00027 19.9 0.0 0.00035 19.5 0.0 1.1 1 0 0 1 1 1 1 Amnionless VSP PF03302.13 EON96005.1 - 0.00037 19.5 0.3 0.00043 19.3 0.3 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.10 EON96005.1 - 0.0012 18.2 1.1 0.0024 17.3 1.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 EON96005.1 - 0.026 14.4 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Trp_oprn_chp PF09534.10 EON96005.1 - 0.039 13.8 0.1 0.051 13.4 0.1 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Nitrate_red_gam PF02665.14 EON96005.1 - 0.053 13.1 0.4 0.077 12.5 0.4 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF4381 PF14316.6 EON96005.1 - 0.083 13.1 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 EON96005.1 - 0.084 13.8 0.0 0.15 13.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5305 PF17231.2 EON96005.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Gram_pos_anchor PF00746.21 EON96005.1 - 0.42 10.6 2.0 1.1 9.2 2.0 1.8 1 1 0 1 1 1 0 LPXTG cell wall anchor motif DUF2613 PF11021.8 EON96005.1 - 4.1 7.6 13.2 1.2 9.3 7.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2613) Cerato-platanin PF07249.12 EON96006.1 - 3.1e-06 27.3 0.1 9.5e-06 25.7 0.1 1.8 1 0 0 1 1 1 1 Cerato-platanin BUD22 PF09073.10 EON96006.1 - 0.39 10.0 2.6 0.63 9.3 2.6 1.3 1 0 0 1 1 1 0 BUD22 GREB1 PF15782.5 EON96006.1 - 1.3 6.0 9.5 1.6 5.7 9.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Aa_trans PF01490.18 EON96008.1 - 1.2e-79 268.0 27.2 1.4e-79 267.8 27.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sugar_tr PF00083.24 EON96009.1 - 6.8e-31 107.6 17.0 7.6e-31 107.5 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2070 PF09843.9 EON96009.1 - 0.083 11.2 3.8 0.1 10.9 3.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TPR_12 PF13424.6 EON96010.1 - 2.5e-11 43.7 11.5 0.0049 17.1 0.2 5.5 4 2 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EON96010.1 - 4.3e-05 23.2 8.5 3.1 7.8 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EON96010.1 - 4.4e-05 23.3 12.6 0.00082 19.3 0.2 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EON96010.1 - 5.9e-05 23.0 6.3 0.075 13.3 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EON96010.1 - 0.0002 21.2 0.9 8.6 6.7 0.2 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_16 PF13191.6 EON96010.1 - 0.00057 20.3 0.0 0.0057 17.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain TPR_19 PF14559.6 EON96010.1 - 0.011 16.2 5.5 0.1 13.1 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EON96010.1 - 0.015 15.7 1.3 8.3 6.8 0.1 4.1 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EON96010.1 - 0.036 14.9 0.2 38 5.5 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EON96010.1 - 0.036 14.7 2.5 1.9 9.2 0.4 3.6 5 0 0 5 5 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EON96010.1 - 0.046 13.8 1.1 3 8.0 0.2 3.0 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 EON96010.1 - 0.059 14.0 0.8 69 4.4 0.0 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat NB-ARC PF00931.22 EON96010.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ParA PF10609.9 EON96010.1 - 0.21 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase TPR_1 PF00515.28 EON96010.1 - 3 7.8 12.4 1.5 8.8 0.5 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EON96010.1 - 8 7.1 8.4 28 5.4 0.3 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat FAD_binding_4 PF01565.23 EON96011.1 - 5.4e-17 61.8 0.7 8.3e-17 61.2 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EON96011.1 - 5.2e-06 26.5 0.0 9.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Bac_rhamnosid6H PF17389.2 EON96012.1 - 7.7e-69 232.5 1.2 1.1e-68 232.1 1.2 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 EON96012.1 - 9.3e-39 133.0 5.8 2.1e-19 70.0 1.0 2.9 3 0 0 3 3 3 2 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 EON96012.1 - 2.9e-18 65.7 0.0 8.2e-18 64.3 0.0 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 EON96012.1 - 1.9e-16 59.6 0.1 4e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF608 PF04685.13 EON96012.1 - 0.034 13.3 0.1 0.054 12.7 0.1 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region SseC PF04888.12 EON96013.1 - 0.0054 16.4 1.6 0.0069 16.0 1.6 1.1 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family DUF917 PF06032.12 EON96013.1 - 0.026 13.4 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) PIG-Y PF15159.6 EON96013.1 - 0.12 13.4 0.1 0.29 12.1 0.1 1.7 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y RPA_C PF08784.11 EON96013.1 - 0.36 11.5 1.8 28 5.4 0.2 2.3 1 1 1 2 2 2 0 Replication protein A C terminal Tape_meas_lam_C PF09718.10 EON96013.1 - 4.7 7.4 11.2 2.6 8.3 3.9 3.0 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ArsB PF02040.15 EON96014.1 - 5.9e-10 39.0 14.7 9.3e-08 31.8 7.4 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein NAD_binding_10 PF13460.6 EON96015.1 - 8.3e-08 32.3 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EON96015.1 - 6.9e-07 29.0 0.0 0.0012 18.4 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EON96015.1 - 3.2e-06 26.9 0.0 4.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 EON96015.1 - 0.00061 20.2 0.0 0.0015 18.9 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EON96015.1 - 0.0091 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 EON96015.1 - 0.017 14.6 0.0 0.65 9.3 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EON96015.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RNA_pol_Rpc34 PF05158.12 EON96016.1 - 1.2e-109 366.8 0.0 1.6e-109 366.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 EON96016.1 - 0.0012 19.5 0.0 0.011 16.4 0.0 2.4 2 1 0 2 2 2 1 Replication protein A C terminal HTH_34 PF13601.6 EON96016.1 - 0.0062 16.7 0.1 0.025 14.7 0.0 2.0 2 0 0 2 2 2 1 Winged helix DNA-binding domain Ribosomal_S25 PF03297.15 EON96016.1 - 0.09 13.0 0.0 0.09 13.0 0.0 2.8 3 0 0 3 3 3 0 S25 ribosomal protein ADH_N PF08240.12 EON96017.1 - 8e-32 109.4 0.1 8e-32 109.4 0.1 1.9 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON96017.1 - 5.6e-21 74.9 0.2 9e-21 74.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EON96017.1 - 1.3e-07 31.3 0.8 2.1e-07 30.6 0.8 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EON96017.1 - 6e-06 27.4 0.0 1.6e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EON96017.1 - 0.00017 21.0 0.9 0.00025 20.4 0.9 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 EON96017.1 - 0.017 14.4 0.4 0.033 13.4 0.3 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON96017.1 - 0.058 12.1 0.5 0.083 11.6 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 EON96017.1 - 0.083 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.21 EON96017.1 - 0.14 12.2 0.4 2.8 8.0 0.4 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Aldo_ket_red PF00248.21 EON96018.1 - 1.4e-50 172.1 0.0 1.6e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phosphoesterase PF04185.14 EON96019.1 - 2.7e-59 201.1 1.1 5.6e-59 200.1 1.1 1.4 1 1 0 1 1 1 1 Phosphoesterase family Mannosidase_ig PF17786.1 EON96020.1 - 1.4e-15 57.7 1.3 2.6e-15 56.8 0.2 2.1 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EON96020.1 - 1.8e-12 47.9 0.9 3.9e-12 46.8 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EON96020.1 - 5.9e-08 32.8 0.0 1.5e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Ig_mannosidase PF17753.1 EON96020.1 - 0.00023 20.8 0.0 0.00076 19.2 0.0 1.9 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 EON96020.1 - 0.0036 16.5 0.1 0.011 14.9 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF3632 PF12311.8 EON96021.1 - 3.8e-33 115.4 3.3 4.5e-31 108.6 3.3 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) NmrA PF05368.13 EON96022.1 - 9.4e-24 84.3 0.2 1.4e-23 83.7 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EON96022.1 - 1.1e-21 77.5 0.1 1.6e-21 77.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EON96022.1 - 0.00014 21.4 0.3 0.00049 19.6 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EON96022.1 - 0.004 17.4 0.4 0.041 14.1 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EON96022.1 - 0.028 13.4 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EON96022.1 - 0.042 13.7 0.1 0.065 13.1 0.1 1.4 1 1 0 1 1 1 0 KR domain Phage_Integr_2 PF13009.6 EON96022.1 - 0.088 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative phage integrase Polysacc_synt_2 PF02719.15 EON96022.1 - 0.13 11.4 0.4 1.2 8.2 0.1 2.4 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.18 EON96023.1 - 3.4e-07 29.6 0.1 5.2e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Syja_N PF02383.18 EON96024.1 - 3.6e-90 302.5 0.0 4.6e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Mur_ligase_M PF08245.12 EON96025.1 - 0.00029 20.9 0.1 0.0048 16.9 0.1 2.7 1 1 0 1 1 1 1 Mur ligase middle domain His_Phos_2 PF00328.22 EON96026.1 - 1.2e-09 38.1 0.0 1.3e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Isochorismatase PF00857.20 EON96027.1 - 3.1e-24 86.1 0.5 3.6e-24 85.9 0.5 1.1 1 0 0 1 1 1 1 Isochorismatase family Pigment_DH PF06324.11 EON96027.1 - 0.13 12.4 1.4 0.25 11.5 1.4 1.4 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) Actin PF00022.19 EON96028.1 - 3.6e-146 486.9 0.0 4.1e-146 486.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EON96028.1 - 0.00025 20.0 0.0 0.12 11.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein DUF1583 PF07622.11 EON96029.1 - 0.077 11.7 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) Tannase PF07519.11 EON96030.1 - 2.6e-116 389.3 0.7 3e-116 389.1 0.7 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 EON96030.1 - 0.015 14.5 0.0 0.18 11.0 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Aldo_ket_red PF00248.21 EON96031.1 - 4.5e-67 226.3 0.0 5.7e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AA_permease_2 PF13520.6 EON96032.1 - 8.7e-41 140.1 42.3 1.3e-40 139.5 42.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EON96032.1 - 1.2e-24 86.8 36.3 1.5e-24 86.4 36.3 1.1 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.8 EON96032.1 - 0.17 11.7 0.2 0.36 10.7 0.2 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Ras PF00071.22 EON96033.1 - 2.3e-58 196.4 0.1 2.7e-58 196.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EON96033.1 - 4.5e-36 123.7 0.1 9e-36 122.7 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EON96033.1 - 8.3e-15 54.7 0.0 9.8e-15 54.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EON96033.1 - 9.7e-07 28.4 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EON96033.1 - 2.8e-06 27.4 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EON96033.1 - 4e-06 26.5 0.0 5.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EON96033.1 - 2.8e-05 24.1 0.8 0.11 12.3 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EON96033.1 - 0.018 15.4 0.2 0.035 14.5 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 EON96033.1 - 0.099 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 EON96033.1 - 0.13 12.5 0.0 4.8 7.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain Abhydrolase_3 PF07859.13 EON96034.1 - 7.6e-64 215.4 0.0 9.6e-64 215.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EON96034.1 - 4.3e-06 25.8 0.0 8.5e-06 24.9 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EON96034.1 - 9.2e-06 25.3 0.0 3.2e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 EON96034.1 - 2.3e-05 23.5 0.1 0.00023 20.2 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase2 PF12740.7 EON96034.1 - 0.00022 20.3 0.0 0.00032 19.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 EON96034.1 - 0.0038 17.9 0.0 0.0068 17.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PhzC-PhzF PF02567.16 EON96034.1 - 0.18 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein adh_short_C2 PF13561.6 EON96035.1 - 4.1e-60 203.3 3.0 4.9e-60 203.0 3.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON96035.1 - 8.2e-48 162.5 4.7 1e-47 162.2 4.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON96035.1 - 4.6e-11 43.0 1.9 6.6e-11 42.4 1.9 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON96035.1 - 1.5e-06 27.9 0.3 3.5e-06 26.7 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family End_tail_spike PF12219.8 EON96035.1 - 0.0044 17.1 0.1 0.0098 16.0 0.0 1.5 1 1 0 1 1 1 1 Catalytic domain of bacteriophage endosialidase Transketolase_C PF02780.20 EON96035.1 - 0.18 11.7 3.4 0.67 9.8 1.4 2.7 2 2 0 2 2 2 0 Transketolase, C-terminal domain SET PF00856.28 EON96036.1 - 1.3e-19 71.2 0.0 6.7e-19 68.9 0.0 2.2 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 EON96036.1 - 3.4e-06 26.7 13.2 0.0022 18.0 4.6 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EON96036.1 - 0.0017 18.4 7.5 0.11 12.7 2.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EON96036.1 - 0.012 15.4 12.2 0.75 9.7 3.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SAF PF08666.12 EON96036.1 - 0.036 14.7 0.0 8.2 7.1 0.0 2.5 2 0 0 2 2 2 0 SAF domain TPR_12 PF13424.6 EON96036.1 - 0.19 12.1 8.2 9.5 6.6 4.6 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EON96036.1 - 0.6 10.3 3.5 12 6.2 0.6 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EON96036.1 - 5.4 7.7 14.8 0.93 10.2 2.3 3.3 2 1 2 4 4 4 0 Tetratricopeptide repeat Ysc84 PF04366.12 EON96037.1 - 1.4e-53 180.0 0.0 3e-53 178.9 0.0 1.6 1 1 0 1 1 1 1 Las17-binding protein actin regulator Band_7 PF01145.25 EON96039.1 - 2.3e-12 47.3 1.3 2.3e-12 47.3 1.3 3.5 2 2 0 2 2 2 1 SPFH domain / Band 7 family ABC_tran PF00005.27 EON96040.1 - 6e-08 33.3 0.2 5.8e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter DUF4440 PF14534.6 EON96041.1 - 2.5e-06 27.8 0.0 3.2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) JmjC PF02373.22 EON96042.1 - 1.6e-37 128.4 0.4 4.1e-37 127.1 0.4 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 EON96042.1 - 8.5e-21 74.2 5.3 2e-20 73.0 5.3 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EON96042.1 - 5.5e-20 71.4 5.8 5.5e-20 71.4 5.8 2.5 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 EON96042.1 - 8.3e-15 54.5 0.3 1.7e-14 53.4 0.3 1.6 1 0 0 1 1 1 1 jmjN domain CENP-B_dimeris PF09026.10 EON96042.1 - 0.03 14.7 0.7 0.03 14.7 0.7 3.8 3 1 0 3 3 3 0 Centromere protein B dimerisation domain DUF604 PF04646.12 EON96043.1 - 1e-07 31.6 0.0 7.4e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF604 Fringe PF02434.16 EON96043.1 - 1.1e-05 25.0 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Fringe-like RasGAP_C PF03836.15 EON96043.1 - 0.08 13.1 1.6 0.14 12.3 1.6 1.3 1 0 0 1 1 1 0 RasGAP C-terminus Peptidase_M1 PF01433.20 EON96044.1 - 8.8e-81 270.6 1.7 1.4e-80 270.0 1.7 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EON96044.1 - 1.1e-80 271.5 0.0 1.5e-79 267.8 0.0 2.4 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EON96044.1 - 2.5e-45 155.0 1.6 5.9e-45 153.7 1.1 1.9 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 EON96044.1 - 0.008 16.2 0.3 0.052 13.5 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2808) VID27 PF08553.10 EON96044.1 - 0.024 13.7 0.1 0.051 12.6 0.1 1.4 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain DUF45 PF01863.17 EON96044.1 - 0.025 14.6 0.1 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF45 Ank_2 PF12796.7 EON96045.1 - 1.9e-30 105.3 6.4 2.7e-12 47.1 0.0 4.3 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EON96045.1 - 2.8e-25 88.0 10.6 5.5e-07 29.7 0.1 6.2 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EON96045.1 - 1.4e-24 86.1 6.7 1.7e-06 28.5 0.1 6.2 3 3 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EON96045.1 - 3.7e-20 71.4 8.6 2.7e-06 27.5 0.0 6.6 6 1 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EON96045.1 - 2.2e-19 67.5 5.1 0.018 15.6 0.0 7.3 8 0 0 8 8 8 5 Ankyrin repeat DUF1843 PF08898.10 EON96045.1 - 0.02 15.4 0.1 13 6.4 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) ARGLU PF15346.6 EON96046.1 - 0.0095 15.8 5.6 0.0095 15.8 5.6 1.9 2 0 0 2 2 2 1 Arginine and glutamate-rich 1 Enolase_N PF03952.16 EON96046.1 - 0.044 14.0 0.9 0.53 10.5 0.1 2.4 2 0 0 2 2 2 0 Enolase, N-terminal domain DUF4404 PF14357.6 EON96046.1 - 0.36 11.5 14.0 0.047 14.3 8.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Prominin PF05478.11 EON96046.1 - 0.52 8.2 4.2 0.81 7.6 4.2 1.2 1 0 0 1 1 1 0 Prominin GRP PF07172.11 EON96046.1 - 2.9 8.7 19.6 0.78 10.5 14.9 2.4 2 0 0 2 2 2 0 Glycine rich protein family Peptidase_S8 PF00082.22 EON96047.1 - 2.2e-24 86.3 1.8 5.6e-23 81.6 1.8 2.1 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EON96047.1 - 7.7e-07 29.8 0.0 1.5e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain An_peroxidase PF03098.15 EON96048.1 - 2.1e-30 105.8 0.5 4.1e-18 65.3 1.7 5.0 1 1 1 2 2 2 2 Animal haem peroxidase Tcp11 PF05794.13 EON96049.1 - 1.1e-101 341.1 0.2 1.1e-101 341.1 0.2 2.8 3 0 0 3 3 3 1 T-complex protein 11 IQ PF00612.27 EON96049.1 - 0.19 11.6 1.6 0.82 9.6 1.6 2.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif UPF0242 PF06785.11 EON96049.1 - 0.47 10.5 9.7 1.1 9.3 9.7 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus 3Beta_HSD PF01073.19 EON96050.1 - 4.6e-09 35.7 0.0 7.9e-09 34.9 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EON96050.1 - 9e-08 31.9 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EON96050.1 - 8.7e-06 25.7 0.0 1.9e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EON96050.1 - 3e-05 23.3 0.0 6.5e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 EON96050.1 - 0.04 13.8 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 KR domain CoA_trans PF01144.23 EON96050.1 - 0.13 11.6 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Coenzyme A transferase Glyco_hydro_61 PF03443.14 EON96051.1 - 1.5e-66 224.3 0.8 2.4e-66 223.6 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 EON96051.1 - 0.096 13.3 0.3 0.18 12.5 0.3 1.4 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading FAD_binding_4 PF01565.23 EON96052.1 - 1.1e-21 77.0 1.0 4.4e-21 75.1 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EON96052.1 - 0.0018 18.3 0.6 0.018 15.1 0.1 2.9 3 0 0 3 3 3 1 Berberine and berberine like GMC_oxred_C PF05199.13 EON96053.1 - 3.5e-31 108.7 0.0 4.6e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Phosphoesterase PF04185.14 EON96054.1 - 1.7e-28 99.8 0.6 1.2e-27 97.1 0.5 2.1 1 1 1 2 2 2 1 Phosphoesterase family Phage_X PF05155.15 EON96054.1 - 0.16 12.4 0.2 2.1 8.8 0.0 2.6 3 0 0 3 3 3 0 Phage X family Glyco_hydro_31 PF01055.26 EON96055.1 - 5.5e-61 207.1 3.6 7e-61 206.7 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 PhyH PF05721.13 EON96056.1 - 1.1e-11 45.5 0.0 2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.18 EON96057.1 - 2.5e-12 46.4 2.0 3.2e-12 46.0 1.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EON96057.1 - 7.7e-08 32.3 7.5 2e-07 31.0 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 EON96058.1 - 3.2e-37 128.4 0.0 3.5e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 EON96059.1 - 1.1e-61 209.1 20.1 9.3e-41 140.1 11.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EON96059.1 - 5.8e-11 41.9 7.5 5.8e-11 41.9 7.5 3.2 2 2 1 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 EON96059.1 - 3.3e-05 22.5 10.1 0.00044 18.8 0.1 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EON96059.1 - 0.00019 20.4 0.4 0.0037 16.2 2.1 2.2 2 1 0 2 2 2 1 MFS_1 like family TPR_10 PF13374.6 EON96060.1 - 0.0066 16.3 0.8 1.9 8.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EON96060.1 - 0.0078 16.5 0.2 4.7 7.6 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR PF01535.20 EON96060.1 - 0.013 15.7 0.1 2.2 8.7 0.0 3.5 3 0 0 3 3 3 0 PPR repeat Prefoldin_2 PF01920.20 EON96061.1 - 1.1e-25 89.6 6.9 1.5e-25 89.2 6.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF1690 PF07956.11 EON96061.1 - 0.0026 18.2 5.6 0.0039 17.6 5.4 1.3 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) Syntaxin-6_N PF09177.11 EON96061.1 - 0.038 14.6 3.9 2.2 8.9 1.0 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF2019 PF09450.10 EON96061.1 - 0.046 13.7 1.2 0.83 9.6 0.3 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF2019) PI3K_P85_iSH2 PF16454.5 EON96061.1 - 0.081 12.5 8.3 0.46 10.1 8.3 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain MtrG PF04210.13 EON96061.1 - 0.13 12.1 0.2 0.13 12.1 0.2 1.8 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G ABC_tran_CTD PF16326.5 EON96061.1 - 0.24 11.7 0.3 0.24 11.7 0.3 2.7 2 1 0 2 2 2 0 ABC transporter C-terminal domain DASH_Dam1 PF08653.10 EON96061.1 - 0.85 9.5 3.0 0.67 9.8 0.3 2.1 2 1 0 2 2 2 0 DASH complex subunit Dam1 DivIC PF04977.15 EON96061.1 - 1.1 9.1 10.1 2.2 8.1 0.5 2.2 2 0 0 2 2 2 0 Septum formation initiator BRO1 PF03097.18 EON96062.1 - 2.4e-123 411.8 0.0 3.7e-123 411.2 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EON96062.1 - 5.3e-90 301.7 0.0 5.3e-90 301.7 0.0 1.8 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV Lysyl_oxidase PF01186.17 EON96062.1 - 0.1 12.2 1.1 0.17 11.5 1.1 1.3 1 0 0 1 1 1 0 Lysyl oxidase MFS_1 PF07690.16 EON96063.1 - 9.9e-16 57.6 24.6 9.9e-16 57.6 24.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON96063.1 - 7.7e-06 25.0 4.8 7.7e-06 25.0 4.8 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter S_4TM PF18159.1 EON96063.1 - 5.6 6.2 4.9 0.7 9.1 0.5 1.7 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain MFS_1 PF07690.16 EON96064.1 - 2.5e-37 128.6 25.1 2.5e-37 128.6 25.1 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_4 PF01063.19 EON96065.1 - 2.8e-17 63.3 0.0 4e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV SHR-BD PF06650.12 EON96066.1 - 1.9e-103 345.6 0.0 1.8e-99 332.5 0.0 2.9 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 EON96066.1 - 9e-95 316.6 23.2 9.1e-92 306.7 1.6 6.6 6 1 0 6 6 6 2 Repeating coiled region of VPS13 VPS13 PF16908.5 EON96066.1 - 7.5e-86 287.8 9.0 7.7e-86 287.7 0.0 4.3 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EON96066.1 - 6.8e-76 254.0 2.3 1.4e-69 233.4 0.1 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EON96066.1 - 1.3e-40 138.1 0.1 5.6e-40 136.1 0.1 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EON96066.1 - 1.5e-07 31.7 0.1 1.4e-06 28.6 0.0 2.5 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain OPT PF03169.15 EON96067.1 - 6.7e-131 437.9 43.9 2.1e-108 363.6 33.3 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein adh_short PF00106.25 EON96068.1 - 1.6e-50 171.3 0.1 2.1e-50 170.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON96068.1 - 2.1e-37 129.0 0.0 2.6e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON96068.1 - 7.4e-13 48.8 0.0 1e-12 48.4 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EON96068.1 - 1.4e-07 31.6 0.2 2.7e-07 30.7 0.2 1.5 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EON96068.1 - 1.5e-05 24.3 0.1 2.1e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EON96068.1 - 0.00051 19.6 0.0 0.00078 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EON96068.1 - 0.0055 16.3 0.1 0.0087 15.6 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.26 EON96068.1 - 0.018 15.0 0.6 0.053 13.5 0.1 2.2 2 1 1 3 3 3 0 Zinc-binding dehydrogenase F420_oxidored PF03807.17 EON96068.1 - 0.097 13.3 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.10 EON96068.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF3429 PF11911.8 EON96069.1 - 1.2e-44 152.1 11.5 1.5e-44 151.8 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) HTH_36 PF13730.6 EON96069.1 - 0.021 14.8 0.0 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Iron_permease PF04120.12 EON96069.1 - 0.24 11.2 1.0 0.48 10.2 1.0 1.5 1 0 0 1 1 1 0 Low affinity iron permease LIM_bind PF01803.16 EON96069.1 - 2.8 7.4 6.0 5 6.6 6.0 1.4 1 0 0 1 1 1 0 LIM-domain binding protein WD40 PF00400.32 EON96070.1 - 2.4e-27 94.6 9.1 0.0001 23.0 0.0 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 EON96070.1 - 3.7e-14 52.3 1.5 3.7e-14 52.3 1.5 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EON96070.1 - 8.5e-07 28.7 1.1 1.9e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 EON96070.1 - 8.7e-05 22.8 0.1 0.78 10.1 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 EON96070.1 - 0.006 16.5 0.2 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 F-box Nup160 PF11715.8 EON96070.1 - 0.017 13.8 0.0 0.096 11.3 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 WD40_like PF17005.5 EON96070.1 - 0.15 11.3 0.1 2.9 7.1 0.0 2.5 2 1 0 2 2 2 0 WD40-like domain MgtE_N PF03448.17 EON96070.1 - 0.2 12.3 0.0 0.47 11.1 0.0 1.6 1 0 0 1 1 1 0 MgtE intracellular N domain Acetyltransf_7 PF13508.7 EON96071.1 - 4e-05 23.9 0.0 6.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EON96071.1 - 0.0003 20.7 0.0 0.00051 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON96071.1 - 0.0028 17.9 0.0 0.0039 17.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EON96071.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EON96071.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 EON96071.1 - 0.2 11.6 0.0 0.55 10.2 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Mannosyl_trans3 PF11051.8 EON96072.1 - 2.4e-31 109.1 0.1 6e-22 78.3 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative Asp_Glu_race PF01177.22 EON96073.1 - 2.8e-46 158.2 0.1 3.4e-46 157.9 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase AroM PF07302.11 EON96073.1 - 0.013 14.9 0.4 1.6 8.0 0.0 2.5 2 1 1 3 3 3 0 AroM protein Pantoate_transf PF02548.15 EON96073.1 - 0.022 14.1 1.1 0.043 13.2 0.2 2.0 2 1 0 2 2 2 0 Ketopantoate hydroxymethyltransferase Amdase PF17645.1 EON96073.1 - 0.069 12.8 0.2 4.5 6.8 0.1 2.5 2 1 0 2 2 2 0 Arylmalonate decarboxylase Actin PF00022.19 EON96074.1 - 9.5e-71 238.5 0.0 1.8e-70 237.6 0.0 1.4 1 1 0 1 1 1 1 Actin Peptidase_S10 PF00450.22 EON96075.1 - 2.6e-70 238.0 0.0 6.4e-70 236.6 0.0 1.5 1 1 1 2 2 2 1 Serine carboxypeptidase TauD PF02668.16 EON96077.1 - 8.2e-13 48.8 0.0 1e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF962 PF06127.11 EON96078.1 - 0.16 12.1 2.5 4.4 7.5 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF962) FtsX PF02687.21 EON96078.1 - 2 9.0 10.5 0.46 11.0 4.2 2.3 2 0 0 2 2 2 0 FtsX-like permease family FAD_binding_4 PF01565.23 EON96079.1 - 1.9e-24 86.0 0.3 3.2e-24 85.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain TauD PF02668.16 EON96081.1 - 9.9e-11 41.9 0.2 1.3e-10 41.6 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EON96081.1 - 0.00049 19.3 0.1 0.00068 18.8 0.1 1.1 1 0 0 1 1 1 1 CsiD FAIM1 PF06905.13 EON96081.1 - 0.06 13.1 0.0 2.3 7.9 0.0 2.0 1 1 1 2 2 2 0 Fas apoptotic inhibitory molecule (FAIM1) DUF4091 PF13320.6 EON96082.1 - 0.013 15.7 0.1 0.31 11.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4091) Snf7 PF03357.21 EON96083.1 - 1.4e-44 151.8 12.2 1.7e-44 151.4 12.2 1.1 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 EON96083.1 - 0.0045 17.4 6.6 0.35 11.4 1.1 3.2 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein Alpha-2-MRAP_C PF06401.11 EON96083.1 - 0.0059 16.6 4.1 0.021 14.8 3.6 1.8 1 1 1 2 2 2 1 Alpha-2-macroglobulin RAP, C-terminal domain CLZ PF16526.5 EON96083.1 - 0.0086 16.4 8.3 0.5 10.8 0.0 3.6 3 1 1 4 4 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF848 PF05852.11 EON96083.1 - 0.018 15.1 5.7 0.028 14.5 5.0 1.7 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) XhlA PF10779.9 EON96083.1 - 0.056 13.7 9.2 0.34 11.2 0.0 3.6 2 1 1 3 3 3 0 Haemolysin XhlA CENP-F_leu_zip PF10473.9 EON96083.1 - 0.06 13.4 9.2 1.3 9.0 9.9 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.6 EON96083.1 - 0.15 12.1 13.4 0.22 11.6 11.6 2.0 1 1 2 3 3 3 0 FlxA-like protein Prominin PF05478.11 EON96083.1 - 0.21 9.5 4.1 0.26 9.2 4.1 1.1 1 0 0 1 1 1 0 Prominin EMP24_GP25L PF01105.24 EON96083.1 - 0.22 11.5 4.7 6.1 6.7 2.6 2.3 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD FliD_C PF07195.12 EON96083.1 - 0.28 10.6 0.0 0.28 10.6 0.0 2.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus FlaC_arch PF05377.11 EON96083.1 - 0.33 11.4 11.1 0.96 9.9 0.0 3.8 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) Mod_r PF07200.13 EON96083.1 - 0.37 10.9 8.0 0.31 11.1 5.7 1.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2205 PF10224.9 EON96083.1 - 0.39 10.7 7.8 1.4 8.9 5.1 3.0 2 1 1 3 3 3 0 Short coiled-coil protein FUSC PF04632.12 EON96083.1 - 0.49 8.9 3.1 2.3 6.6 0.7 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family Wtap PF17098.5 EON96083.1 - 0.54 10.2 7.3 2.4 8.1 7.3 2.0 1 1 0 1 1 1 0 WTAP/Mum2p family ABC_tran_CTD PF16326.5 EON96083.1 - 1.4 9.2 12.7 3.5 7.9 0.0 3.5 1 1 2 3 3 3 0 ABC transporter C-terminal domain Atg14 PF10186.9 EON96083.1 - 4.8 6.2 7.7 10 5.1 7.7 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Aldo_ket_red PF00248.21 EON96085.1 - 2.8e-69 233.5 0.0 3.6e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BioW PF03744.13 EON96086.1 - 0.035 13.7 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase Amidohydro_1 PF01979.20 EON96087.1 - 2.2e-33 116.0 0.0 2.6e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EON96087.1 - 1.6e-09 37.8 0.4 4.4e-08 33.0 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family Asparaginase_2 PF01112.18 EON96089.1 - 1.8e-69 234.1 8.4 2.4e-69 233.7 8.4 1.1 1 0 0 1 1 1 1 Asparaginase RANK_CRD_2 PF18278.1 EON96089.1 - 0.091 12.9 0.5 0.091 12.9 0.5 1.9 2 0 0 2 2 2 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 MatE PF01554.18 EON96090.1 - 1.9e-33 115.4 25.7 2.8e-20 72.6 12.6 3.0 2 1 1 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EON96090.1 - 0.0055 16.8 7.0 0.0055 16.8 7.0 3.2 1 1 1 3 3 3 2 Polysaccharide biosynthesis C-terminal domain NCBP3 PF10309.9 EON96091.1 - 1.3e-17 63.4 0.1 2.5e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RRM_occluded PF16842.5 EON96091.1 - 0.15 12.0 0.1 0.37 10.7 0.1 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif ABC_membrane PF00664.23 EON96092.1 - 2e-53 181.8 10.8 2.6e-53 181.4 10.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EON96092.1 - 3.4e-33 115.0 0.0 1e-32 113.5 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EON96092.1 - 1.6e-05 24.5 0.0 0.00055 19.4 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EON96092.1 - 0.0015 18.8 0.1 0.0096 16.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EON96092.1 - 0.0093 16.4 0.2 0.12 12.9 0.2 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EON96092.1 - 0.011 15.5 0.1 0.026 14.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EON96092.1 - 0.015 15.1 0.1 0.45 10.2 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 EON96092.1 - 0.03 14.3 0.1 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EON96092.1 - 0.047 14.1 2.2 0.071 13.5 0.2 2.4 3 1 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 EON96092.1 - 0.11 13.0 0.3 0.39 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 EON96092.1 - 0.13 12.4 0.0 0.74 9.9 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain SbcCD_C PF13558.6 EON96092.1 - 0.14 12.4 1.4 2 8.7 1.4 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Ribosomal_S3Ae PF01015.18 EON96093.1 - 2.7e-89 298.1 1.3 3.3e-89 297.8 1.3 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 EON96093.1 - 0.021 15.3 0.1 0.08 13.5 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor SUI1 NEMO PF11577.8 EON96093.1 - 0.066 13.2 1.3 0.41 10.7 0.0 2.5 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Abhydro_lipase PF04083.16 EON96093.1 - 0.18 11.4 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DNA_pol_B_palm PF14792.6 EON96094.1 - 1.6e-21 76.7 0.1 4.3e-21 75.2 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EON96094.1 - 1e-20 73.7 0.1 2.6e-20 72.4 0.1 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EON96094.1 - 1.2e-19 69.9 0.7 3.7e-19 68.3 0.7 1.9 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 EON96094.1 - 2.1e-11 44.0 0.1 4.1e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 EON96094.1 - 0.05 13.9 0.4 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Nucleotidyltransferase domain DnaJ PF00226.31 EON96095.1 - 1.2e-20 73.4 0.5 3.8e-20 71.8 0.5 2.0 1 0 0 1 1 1 1 DnaJ domain Fibrillarin PF01269.17 EON96096.1 - 5.4e-104 346.2 0.0 6.7e-104 346.0 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EON96096.1 - 1.8e-05 24.5 0.0 2.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 EON96096.1 - 0.049 13.3 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 EON96096.1 - 0.096 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GFO_IDH_MocA PF01408.22 EON96097.1 - 8.2e-22 78.3 0.0 1.3e-21 77.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EON96097.1 - 4.8e-06 26.6 0.0 8.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EON96097.1 - 0.019 15.6 0.0 0.034 14.8 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain AAA_33 PF13671.6 EON96097.1 - 0.06 13.5 0.0 0.16 12.1 0.0 1.5 1 1 1 2 2 2 0 AAA domain FAD_binding_3 PF01494.19 EON96098.1 - 4.4e-75 253.1 0.0 5.6e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EON96098.1 - 1.6e-06 27.9 0.1 0.018 14.6 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EON96098.1 - 0.0002 21.5 0.0 0.00046 20.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EON96098.1 - 0.004 15.9 0.0 0.41 9.3 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 EON96098.1 - 0.0047 16.2 0.0 0.22 10.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON96098.1 - 0.027 13.6 0.1 0.5 9.4 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 EON96098.1 - 0.077 12.2 0.1 0.31 10.2 0.0 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EON96098.1 - 0.081 12.0 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox PF00070.27 EON96098.1 - 0.2 12.2 0.3 0.84 10.2 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HNH_2 PF13391.6 EON96099.1 - 0.013 15.7 0.0 0.029 14.5 0.0 1.7 1 0 0 1 1 1 0 HNH endonuclease CLP_protease PF00574.23 EON96100.1 - 2.5e-51 174.1 0.2 3.1e-51 173.9 0.2 1.1 1 0 0 1 1 1 1 Clp protease Peptidase_M22 PF00814.25 EON96101.1 - 9.9e-81 271.4 0.0 1.2e-80 271.1 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EON96101.1 - 0.19 11.4 0.0 1.5 8.4 0.0 2.0 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus UPRTase PF14681.6 EON96102.1 - 1.4e-78 263.1 0.0 1.8e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EON96102.1 - 0.005 16.4 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Glyco_hydro_3_C PF01915.22 EON96103.1 - 1.1e-50 172.4 0.0 1.6e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EON96103.1 - 2.1e-24 85.4 0.0 3.5e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 EON96103.1 - 3.4e-24 85.8 0.0 6.2e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Vps39_2 PF10367.9 EON96104.1 - 1.1e-08 35.5 0.0 2.9e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 EON96104.1 - 0.0012 19.1 0.0 0.012 15.9 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Katanin_con80 PF13925.6 EON96104.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 con80 domain of Katanin NAP PF00956.18 EON96105.1 - 8e-101 336.8 11.5 8e-101 336.8 11.5 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Nop14 PF04147.12 EON96105.1 - 4.6 5.3 33.2 0.36 9.0 21.7 2.1 2 0 0 2 2 2 0 Nop14-like family Sec23_trunk PF04811.15 EON96106.1 - 1e-80 270.9 0.0 1.4e-80 270.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EON96106.1 - 2.5e-30 105.1 0.2 5.3e-30 104.0 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EON96106.1 - 1.5e-25 89.0 0.1 4.5e-25 87.5 0.1 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EON96106.1 - 6.1e-16 58.2 6.1 1.2e-15 57.3 6.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EON96106.1 - 4.9e-12 45.6 0.0 1.3e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EON96106.1 - 0.042 13.2 1.0 0.09 12.2 0.1 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Spt4 PF06093.13 EON96107.1 - 9.7e-32 108.9 0.0 1.2e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.11 EON96107.1 - 0.15 12.0 0.2 0.41 10.7 0.1 1.8 1 1 1 2 2 2 0 Coronavirus gene 5 protein DNA_primase_lrg PF04104.14 EON96108.1 - 2.6e-83 279.5 0.0 4e-83 278.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Methyltransf_23 PF13489.6 EON96109.1 - 2e-06 27.8 0.0 3.4e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON96109.1 - 0.00086 19.1 0.0 0.78 9.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EON96109.1 - 0.032 14.9 0.0 0.26 12.0 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Kin17_mid PF10357.9 EON96110.1 - 1.2e-52 177.1 1.1 1.2e-52 177.1 1.1 2.2 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 EON96110.1 - 7.5e-06 26.1 0.5 2.3e-05 24.5 0.2 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EON96110.1 - 0.00011 22.4 2.1 0.00018 21.8 1.0 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EON96110.1 - 0.00058 20.1 2.6 0.0011 19.3 0.3 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF5105 PF17118.5 EON96110.1 - 0.029 14.2 0.0 0.087 12.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5105) DUF3906 PF13046.6 EON96110.1 - 0.069 13.2 0.1 0.5 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) Menin PF05053.13 EON96110.1 - 0.17 10.2 9.9 0.23 9.8 9.9 1.1 1 0 0 1 1 1 0 Menin 2-Hacid_dh_C PF02826.19 EON96111.1 - 8e-53 178.4 0.0 1.2e-52 177.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EON96111.1 - 8.1e-36 122.6 0.0 1e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EON96111.1 - 0.00074 19.7 0.1 0.0014 18.8 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EON96111.1 - 0.0082 16.2 0.2 0.022 14.8 0.0 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 EON96111.1 - 0.031 13.8 0.0 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 EON96111.1 - 0.049 14.1 0.0 0.26 11.8 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain ACT PF01842.25 EON96111.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 ACT domain 3HCDH_N PF02737.18 EON96111.1 - 0.13 12.1 1.3 3.9 7.3 0.5 2.7 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_18 PF13238.6 EON96112.1 - 2e-27 96.3 1.0 4.5e-27 95.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EON96112.1 - 2.5e-08 34.5 0.1 1.4e-07 32.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain ADK PF00406.22 EON96112.1 - 7.8e-06 26.1 0.1 0.0083 16.2 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA PF00004.29 EON96112.1 - 6e-05 23.5 0.0 0.00086 19.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EON96112.1 - 0.0001 22.5 0.2 0.0088 16.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 EON96112.1 - 0.00018 21.8 0.3 0.0018 18.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 EON96112.1 - 0.0009 19.4 0.5 0.0042 17.2 0.5 1.8 1 1 0 1 1 1 1 Shikimate kinase NTPase_1 PF03266.15 EON96112.1 - 0.0025 17.7 0.8 0.0056 16.6 0.2 1.9 2 0 0 2 2 2 1 NTPase Thymidylate_kin PF02223.17 EON96112.1 - 0.0051 16.5 0.2 2.9 7.5 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Hydin_ADK PF17213.3 EON96112.1 - 0.0086 16.4 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain AAA_22 PF13401.6 EON96112.1 - 0.016 15.5 0.5 0.057 13.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 EON96112.1 - 0.02 14.3 0.2 0.079 12.4 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 dNK PF01712.19 EON96112.1 - 0.026 14.4 3.7 2.4 7.9 0.2 2.1 1 1 0 2 2 2 0 Deoxynucleoside kinase AAA_16 PF13191.6 EON96112.1 - 0.052 13.9 0.2 0.079 13.3 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EON96112.1 - 0.063 13.0 2.9 1.8 8.3 0.5 2.8 2 1 1 3 3 3 0 AAA domain RuvB_N PF05496.12 EON96112.1 - 0.071 12.9 0.3 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EON96112.1 - 0.088 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 EON96112.1 - 0.16 12.5 1.3 0.74 10.3 1.3 2.0 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 EON96112.1 - 0.25 11.5 0.5 0.84 9.7 0.5 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EON96112.1 - 0.43 10.3 2.8 0.32 10.7 0.5 2.1 2 2 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EON96112.1 - 0.78 10.1 3.6 0.41 11.0 0.9 2.0 2 1 1 3 3 3 0 AAA domain MAPEG PF01124.18 EON96113.1 - 1.1e-21 77.0 0.2 1.4e-21 76.8 0.2 1.1 1 0 0 1 1 1 1 MAPEG family CTD_bind PF04818.13 EON96114.1 - 2.1e-13 50.9 0.1 5.9e-13 49.4 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. MCD_N PF17408.2 EON96114.1 - 0.0017 18.4 0.1 0.0048 17.0 0.1 1.7 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain CREPT PF16566.5 EON96114.1 - 0.016 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Enkurin PF13864.6 EON96114.1 - 0.1 13.0 0.9 15 6.1 0.0 2.5 2 0 0 2 2 2 0 Calmodulin-binding EPL1 PF10513.9 EON96116.1 - 1.9e-21 77.1 1.5 1.9e-21 77.1 1.5 2.0 2 0 0 2 2 2 1 Enhancer of polycomb-like IF3_C PF00707.22 EON96116.1 - 0.58 10.2 4.7 2.8 8.0 0.3 3.1 3 0 0 3 3 3 0 Translation initiation factor IF-3, C-terminal domain Beta-lactamase PF00144.24 EON96117.1 - 7.2e-09 35.3 0.2 1.2e-08 34.6 0.1 1.4 2 0 0 2 2 2 1 Beta-lactamase F-box PF00646.33 EON96119.1 - 0.15 12.0 0.0 0.42 10.6 0.0 1.8 1 0 0 1 1 1 0 F-box domain EntA_Immun PF08951.10 EON96119.1 - 1.8 9.0 5.7 1.7 9.1 0.6 3.1 3 0 0 3 3 3 0 Enterocin A Immunity Sugar_tr PF00083.24 EON96120.1 - 2.9e-39 135.2 0.9 3.3e-39 135.0 0.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON96120.1 - 1.6e-17 63.5 2.3 2e-17 63.1 2.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_5 PF05631.14 EON96120.1 - 0.0019 17.2 0.4 0.003 16.6 0.4 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 EON96120.1 - 0.047 12.5 4.1 0.033 13.0 2.6 1.4 2 0 0 2 2 2 0 MFS_1 like family Ribosomal_L11_N PF03946.14 EON96121.1 - 7e-25 86.6 0.3 1.2e-24 85.9 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EON96121.1 - 2.7e-16 59.8 0.2 5.1e-16 58.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Met_asp_mut_E PF06368.11 EON96121.1 - 0.012 14.1 0.4 0.015 13.8 0.4 1.0 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) ROS_MUCR PF05443.11 EON96121.1 - 0.068 13.2 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein NIF PF03031.18 EON96122.1 - 4.9e-20 71.9 0.0 6.2e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Elf1 PF05129.13 EON96123.1 - 0.029 14.4 0.1 0.029 14.4 0.1 2.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like ILVD_EDD PF00920.21 EON96124.1 - 6.8e-211 701.4 0.1 7.8e-211 701.2 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Peptidase_C12 PF01088.21 EON96127.1 - 2.6e-68 229.9 0.0 3.2e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EON96127.1 - 2.4e-10 40.1 0.1 5.5e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Glyco_hydro_47 PF01532.20 EON96128.1 - 5e-172 572.9 0.0 5.8e-172 572.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Sugar_tr PF00083.24 EON96129.1 - 2.2e-05 23.5 0.7 2.4e-05 23.4 0.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Lipoxygenase PF00305.19 EON96129.1 - 0.14 10.5 0.0 0.15 10.4 0.0 1.0 1 0 0 1 1 1 0 Lipoxygenase PspC PF04024.12 EON96129.1 - 0.73 9.7 3.6 1 9.2 3.6 1.4 1 1 0 1 1 1 0 PspC domain MIP PF00230.20 EON96130.1 - 3.4e-33 115.3 12.1 4e-33 115.0 12.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein Abhydrolase_1 PF00561.20 EON96132.1 - 1e-17 64.6 0.0 6.3e-17 62.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON96132.1 - 3.7e-10 40.8 0.1 5.4e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON96132.1 - 5.8e-07 29.0 0.0 8.6e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EON96132.1 - 0.00065 19.9 0.0 0.00092 19.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 EON96132.1 - 0.00075 19.2 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 EON96132.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Ndr PF03096.14 EON96132.1 - 0.018 13.8 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family Lipase_3 PF01764.25 EON96132.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 EON96132.1 - 0.18 10.7 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Clathrin_lg_ch PF01086.17 EON96133.1 - 7.1e-75 252.0 6.8 8e-75 251.8 6.8 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF4407 PF14362.6 EON96133.1 - 2.4 7.5 5.4 1 8.7 2.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SNARE PF05739.19 EON96134.1 - 1.8e-15 56.7 0.4 3.7e-15 55.6 0.4 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EON96134.1 - 4.6e-05 23.2 10.1 0.0043 16.7 0.4 2.3 2 0 0 2 2 2 2 Syntaxin DASH_Dad4 PF08650.10 EON96134.1 - 0.049 13.6 0.4 2 8.5 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad4 MCPsignal PF00015.21 EON96134.1 - 0.086 12.6 7.2 0.25 11.2 0.5 2.8 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Fer2_BFD PF04324.15 EON96134.1 - 0.16 12.4 0.2 0.43 11.0 0.2 1.7 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain Syntaxin_2 PF14523.6 EON96134.1 - 0.27 11.6 8.5 2 8.8 2.4 2.6 2 1 0 2 2 2 0 Syntaxin-like protein DNA_repr_REX1B PF14966.6 EON96134.1 - 0.5 11.1 3.8 0.37 11.5 0.4 2.4 2 1 0 2 2 2 0 DNA repair REX1-B ATP-cone PF03477.16 EON96134.1 - 0.64 10.6 7.9 0.82 10.3 0.6 3.0 3 0 0 3 3 3 0 ATP cone domain SlyX PF04102.12 EON96134.1 - 2.5 8.8 10.8 1.6 9.4 0.3 3.5 2 2 1 3 3 3 0 SlyX DUF3958 PF13125.6 EON96134.1 - 4.4 7.5 8.0 1.1 9.4 3.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) MFS_1 PF07690.16 EON96135.1 - 8.6e-18 64.4 10.3 1e-17 64.1 10.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily RRM_DME PF15628.6 EON96136.1 - 0.011 15.9 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 RRM in Demeter Xan_ur_permease PF00860.20 EON96137.1 - 2.7e-31 108.6 24.4 7.2e-17 61.2 7.0 3.2 3 1 0 3 3 3 3 Permease family Pox_A32 PF04665.12 EON96137.1 - 0.19 11.2 0.3 0.3 10.5 0.3 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein CASP_C PF08172.12 EON96138.1 - 2.5e-93 312.0 0.0 2.5e-93 312.0 0.0 3.2 3 0 0 3 3 3 1 CASP C terminal MscS_porin PF12795.7 EON96138.1 - 0.00047 19.8 54.4 0.031 13.8 1.4 4.5 4 1 0 4 4 4 3 Mechanosensitive ion channel porin domain bZIP_2 PF07716.15 EON96138.1 - 0.0032 17.5 4.0 0.0032 17.5 4.0 8.2 6 3 2 9 9 8 1 Basic region leucine zipper LMBR1 PF04791.16 EON96138.1 - 0.039 12.9 0.1 0.039 12.9 0.1 3.0 2 1 0 2 2 1 0 LMBR1-like membrane protein UPF0184 PF03670.13 EON96138.1 - 0.056 13.8 0.4 0.056 13.8 0.4 3.7 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0184) ZapB PF06005.12 EON96138.1 - 0.08 13.4 0.3 0.08 13.4 0.3 6.7 6 1 1 7 7 7 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 EON96138.1 - 0.082 13.0 68.1 0.058 13.5 8.3 6.8 5 1 1 6 6 6 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 EON96138.1 - 0.37 11.0 64.7 0.52 10.5 0.1 6.3 2 1 2 5 5 5 0 Autophagy protein 16 (ATG16) Metal_resist PF13801.6 EON96138.1 - 0.54 10.5 0.0 0.54 10.5 0.0 4.4 4 1 1 5 5 5 0 Heavy-metal resistance SKA1 PF07160.12 EON96138.1 - 0.79 9.5 29.2 2.3 8.0 1.2 4.6 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 1 DUF4482 PF14818.6 EON96138.1 - 1.1 10.1 0.0 1.1 10.1 0.0 5.4 4 1 2 6 6 5 0 Domain of unknown function (DUF4482) ERM PF00769.19 EON96138.1 - 1.4 8.7 57.3 0.046 13.5 6.1 5.0 3 1 2 5 5 5 0 Ezrin/radixin/moesin family ADIP PF11559.8 EON96138.1 - 1.7 8.7 67.4 0.07 13.2 7.0 7.1 5 1 2 7 7 7 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 EON96138.1 - 2.8 7.4 51.5 3.2 7.3 8.6 3.8 3 1 1 4 4 4 0 Intermediate filament protein SOGA PF11365.8 EON96138.1 - 5.5 8.2 38.4 0.27 12.4 4.0 5.9 2 1 4 6 6 6 0 Protein SOGA SMODS PF18144.1 EON96138.1 - 5.7 7.1 7.4 1.1 9.4 0.1 3.3 3 1 0 3 3 3 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain DUF3584 PF12128.8 EON96138.1 - 6.2 4.2 52.9 0.25 8.8 8.7 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3584) DUF4200 PF13863.6 EON96138.1 - 7.7 6.9 51.5 3.9 7.9 1.5 6.0 4 1 2 6 6 6 0 Domain of unknown function (DUF4200) Ribosomal_L22 PF00237.19 EON96139.1 - 1e-40 138.1 0.1 1.5e-40 137.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e LTD PF00932.19 EON96139.1 - 0.12 12.8 0.0 0.19 12.1 0.0 1.4 1 1 0 1 1 1 0 Lamin Tail Domain HSP90 PF00183.18 EON96140.1 - 1.1e-221 737.3 28.3 1.4e-221 736.9 28.3 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EON96140.1 - 8.3e-16 58.5 0.1 1.5e-15 57.6 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EON96140.1 - 4.4e-10 39.5 0.2 1.3e-09 38.0 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 EON96140.1 - 0.055 13.5 0.3 0.2 11.7 0.3 1.9 1 0 0 1 1 1 0 Tumour suppressor protein DUF1676 PF07898.13 EON96140.1 - 0.77 9.8 4.0 0.52 10.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) EF-hand_1 PF00036.32 EON96141.1 - 1.1e-36 121.7 14.8 9.2e-10 37.4 0.9 5.1 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 EON96141.1 - 7.4e-35 118.6 7.0 2.9e-15 55.8 0.6 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 EON96141.1 - 4.5e-33 113.5 5.6 4.9e-19 68.6 2.2 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EON96141.1 - 7.1e-25 84.8 12.3 9.5e-09 34.5 0.0 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 EON96141.1 - 3.2e-23 80.1 9.0 1.2e-05 24.6 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EON96141.1 - 1.5e-13 50.9 0.7 1.7e-06 28.2 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EON96141.1 - 2.6e-08 33.7 1.7 0.00097 19.1 0.3 2.5 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EON96141.1 - 8.4e-08 32.5 0.2 0.002 18.4 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 EON96141.1 - 1.5e-06 28.1 0.1 0.0095 15.9 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EON96141.1 - 2.4e-05 24.3 2.0 3e-05 24.0 0.2 2.1 3 0 0 3 3 2 1 Ca2+ insensitive EF hand TerB PF05099.13 EON96141.1 - 9.3e-05 22.4 1.5 0.094 12.7 0.2 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB EF-hand_11 PF08976.11 EON96141.1 - 0.00026 21.8 0.1 0.0028 18.5 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain RNA_pol_Rpb4 PF03874.16 EON96141.1 - 0.00073 19.9 0.7 0.66 10.3 0.2 2.8 2 1 0 2 2 2 2 RNA polymerase Rpb4 DUF5580 PF17743.1 EON96141.1 - 0.0073 14.9 0.0 0.0077 14.8 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Dockerin_1 PF00404.18 EON96141.1 - 0.0086 16.2 6.7 0.46 10.7 0.8 3.0 1 1 2 3 3 3 2 Dockerin type I domain SurA_N_2 PF13623.6 EON96141.1 - 0.013 15.3 1.1 0.55 10.1 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain Caleosin PF05042.13 EON96141.1 - 0.016 15.1 1.0 19 5.2 0.0 3.6 1 1 3 4 4 4 0 Caleosin related protein Poly_export PF02563.16 EON96141.1 - 0.033 14.4 0.0 0.32 11.3 0.0 2.4 2 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein RuvA_C PF07499.13 EON96141.1 - 0.087 13.3 0.1 10 6.7 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 EON96141.1 - 0.16 12.1 0.3 1.4 9.1 0.0 2.2 1 1 0 2 2 2 0 Transcription factor MotA, activation domain DUF5132 PF17195.4 EON96141.1 - 0.2 11.8 0.5 23 5.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Excalibur PF05901.11 EON96141.1 - 4 8.1 5.4 88 3.8 0.0 3.7 4 0 0 4 4 4 0 Excalibur calcium-binding domain Abhydrolase_6 PF12697.7 EON96142.1 - 2e-08 35.1 0.0 2.3e-08 34.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family EF1G PF00647.19 EON96143.1 - 7.7e-43 144.9 0.0 1.4e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 EON96143.1 - 1.4e-15 57.2 0.0 4.3e-15 55.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EON96143.1 - 1.5e-10 41.0 0.2 4.4e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EON96143.1 - 2e-08 34.5 0.1 1.1e-07 32.1 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EON96143.1 - 1e-05 25.7 0.0 3.4e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EON96143.1 - 0.00043 20.6 0.0 0.00093 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EON96143.1 - 0.043 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NACHT_N PF17100.5 EON96144.1 - 3.3e-54 184.1 2.0 3.3e-54 184.1 2.0 2.7 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase Ank_4 PF13637.6 EON96144.1 - 2.7e-14 53.3 0.1 1.1e-06 29.0 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EON96144.1 - 3.1e-11 43.7 0.0 2.5e-05 24.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EON96144.1 - 2.8e-09 37.0 0.0 0.00068 20.0 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EON96144.1 - 4.6e-07 30.0 0.0 0.00029 21.1 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) AAA_16 PF13191.6 EON96144.1 - 2.3e-06 28.1 1.1 2.2e-05 24.9 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain Ank_3 PF13606.6 EON96144.1 - 5e-05 23.4 0.0 0.69 10.7 0.0 4.5 4 0 0 4 4 3 1 Ankyrin repeat AAA_22 PF13401.6 EON96144.1 - 0.0062 16.8 0.1 0.03 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain VSG_B PF13206.6 EON96144.1 - 0.044 13.1 8.9 0.079 12.2 8.9 1.4 1 0 0 1 1 1 0 Trypanosomal VSG domain AAA_18 PF13238.6 EON96144.1 - 0.23 12.0 2.0 1.5 9.4 0.1 3.1 2 1 0 2 2 2 0 AAA domain DUF2730 PF10805.8 EON96144.1 - 0.31 11.1 6.0 0.53 10.4 3.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DALR_1 PF05746.15 EON96144.1 - 0.33 11.2 4.2 0.4 10.9 2.4 2.2 2 0 0 2 2 2 0 DALR anticodon binding domain TF_AP-2 PF03299.14 EON96144.1 - 1.4 8.8 6.4 4.2 7.3 6.4 1.7 1 0 0 1 1 1 0 Transcription factor AP-2 PIN_8 PF18476.1 EON96144.1 - 8.6 6.1 13.2 4.6 7.0 9.3 2.4 2 1 0 2 2 2 0 PIN like domain Sec7 PF01369.20 EON96145.1 - 5.7e-21 75.0 0.3 8.4e-21 74.5 0.3 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 EON96145.1 - 2.5e-05 24.7 0.1 9.2e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 PH domain RNA_pol_3_Rpc31 PF11705.8 EON96145.1 - 0.00074 19.8 4.7 0.0017 18.7 4.7 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PH_9 PF15410.6 EON96145.1 - 0.00094 19.5 0.1 0.0019 18.5 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain NOA36 PF06524.12 EON96145.1 - 3.5 6.9 5.5 5.7 6.2 5.5 1.2 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 EON96145.1 - 6.5 5.8 7.5 11 5.1 7.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-B_dimeris PF09026.10 EON96145.1 - 7.3 7.1 12.1 18 5.8 12.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Myosin_head PF00063.21 EON96146.1 - 9.4e-260 863.5 0.4 1.4e-259 862.9 0.4 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 EON96146.1 - 4.7e-27 94.3 2.6 3.2e-26 91.6 2.6 2.6 1 0 0 1 1 1 1 DIL domain IQ PF00612.27 EON96146.1 - 8.1e-15 53.2 36.6 9.8e-05 21.8 0.8 7.1 6 0 0 6 6 6 5 IQ calmodulin-binding motif GAS PF13851.6 EON96146.1 - 0.00078 18.8 12.5 0.00078 18.8 12.5 2.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Myosin_N PF02736.19 EON96146.1 - 0.00091 19.0 1.7 0.0021 17.8 1.7 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain ERM PF00769.19 EON96146.1 - 0.0036 17.2 21.4 0.011 15.6 21.4 1.8 1 0 0 1 1 1 1 Ezrin/radixin/moesin family AAA_22 PF13401.6 EON96146.1 - 0.0038 17.5 0.0 0.014 15.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain CENP-F_leu_zip PF10473.9 EON96146.1 - 0.006 16.6 20.9 0.13 12.2 3.0 2.7 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.11 EON96146.1 - 0.0086 15.0 21.1 0.016 14.1 21.1 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_16 PF13191.6 EON96146.1 - 0.013 15.9 0.5 0.18 12.1 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain Fez1 PF06818.15 EON96146.1 - 0.027 14.9 19.3 0.075 13.5 8.4 2.6 1 1 1 2 2 2 0 Fez1 FlaC_arch PF05377.11 EON96146.1 - 0.031 14.7 0.6 0.031 14.7 0.6 4.5 3 1 0 4 4 4 0 Flagella accessory protein C (FlaC) HSF_DNA-bind PF00447.17 EON96146.1 - 0.069 13.8 0.4 0.35 11.5 0.4 2.2 1 0 0 1 1 1 0 HSF-type DNA-binding DUF4136 PF13590.6 EON96146.1 - 0.41 11.2 5.0 1 9.9 0.7 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4136) ATG16 PF08614.11 EON96146.1 - 0.78 9.9 28.4 2 8.6 5.9 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 EON96146.1 - 0.98 9.9 28.3 0.39 11.2 19.1 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region Sec34 PF04136.15 EON96146.1 - 1 9.2 6.8 0.36 10.7 2.6 2.3 1 1 1 2 2 2 0 Sec34-like family Baculo_PEP_C PF04513.12 EON96146.1 - 1.6 8.8 12.0 1.9 8.6 8.5 3.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.11 EON96146.1 - 2.1 8.1 13.7 0.46 10.3 7.4 2.6 1 1 2 3 3 3 0 Phage minor structural protein GP20 BST2 PF16716.5 EON96146.1 - 3.8 8.2 18.7 0.52 10.9 2.7 3.8 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 BRE1 PF08647.11 EON96146.1 - 7.4 6.7 21.3 17 5.6 4.1 3.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase AA_kinase PF00696.28 EON96147.1 - 8.7e-32 110.6 0.5 2.3e-30 106.0 0.1 2.7 2 1 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 EON96147.1 - 3.4e-15 55.5 0.3 3e-08 33.3 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 EON96147.1 - 2e-13 49.9 3.6 3.3e-10 39.6 0.3 2.6 2 0 0 2 2 2 2 ACT domain DUF2808 PF10989.8 EON96147.1 - 0.22 11.5 0.6 0.49 10.4 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) Kinesin PF00225.23 EON96148.1 - 2.6e-104 348.7 0.5 2.6e-104 348.7 0.5 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EON96148.1 - 1.9e-54 183.7 0.2 1.1e-53 181.2 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding DEAD PF00270.29 EON96148.1 - 0.0079 16.0 0.9 3.3 7.4 0.1 2.9 1 1 1 2 2 2 2 DEAD/DEAH box helicase AAA_16 PF13191.6 EON96148.1 - 0.21 12.0 0.0 0.21 12.0 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EON96148.1 - 1.3 9.3 6.9 0.61 10.4 0.5 3.2 2 1 0 2 2 2 0 AAA domain WEMBL PF05701.11 EON96148.1 - 1.8 7.2 45.2 0.041 12.6 34.5 2.1 2 0 0 2 2 2 0 Weak chloroplast movement under blue light Baculo_PEP_C PF04513.12 EON96148.1 - 4.6 7.3 8.9 19 5.3 1.7 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GTP_CH_N PF12471.8 EON96149.1 - 1.6e-92 308.5 0.0 2.3e-92 308.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EON96149.1 - 2e-15 56.8 0.0 3e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II zf-C2H2 PF00096.26 EON96150.1 - 8.9e-06 25.9 18.8 0.21 12.1 1.2 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type TT_ORF2 PF02957.15 EON96150.1 - 0.021 15.8 2.1 0.058 14.3 2.1 1.7 1 0 0 1 1 1 0 TT viral ORF2 zf-TAZ PF02135.16 EON96150.1 - 0.14 12.6 3.8 0.27 11.7 1.6 2.1 2 0 0 2 2 2 0 TAZ zinc finger zf-C2HE PF16278.5 EON96150.1 - 0.14 12.6 1.1 6.5 7.3 0.2 2.6 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_4 PF13894.6 EON96150.1 - 0.17 12.8 20.6 0.43 11.5 0.9 4.8 4 1 0 4 4 4 0 C2H2-type zinc finger Acyltransferase PF01553.21 EON96151.1 - 0.0029 17.2 0.0 0.0084 15.7 0.0 1.7 1 1 0 1 1 1 1 Acyltransferase BAG6 PF12057.8 EON96151.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 BCL2-associated athanogene 6 Ham1p_like PF01725.16 EON96152.1 - 5e-59 199.4 0.0 5.7e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family p450 PF00067.22 EON96153.1 - 0.003 16.4 0.0 0.028 13.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 DUF4702 PF15774.5 EON96153.1 - 0.056 12.4 0.0 0.096 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) Methyltransf_16 PF10294.9 EON96154.1 - 1e-11 44.9 0.0 1.5e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EON96154.1 - 0.0084 15.5 0.0 0.016 14.6 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Peptidase_C78 PF07910.13 EON96155.1 - 4.9e-67 225.5 0.0 8.3e-67 224.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C47 PF05543.13 EON96155.1 - 0.022 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Staphopain peptidase C47 zf-Di19 PF05605.12 EON96155.1 - 0.044 14.1 0.4 0.39 11.1 0.0 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EON96155.1 - 0.1 13.5 0.3 3.1 8.9 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Ku_C PF03730.14 EON96155.1 - 0.15 12.8 0.2 0.38 11.5 0.1 1.8 1 1 0 1 1 1 0 Ku70/Ku80 C-terminal arm Peptidase_C39_2 PF13529.6 EON96155.1 - 0.16 12.5 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase_C39 like family MBOAT PF03062.19 EON96156.1 - 7.1e-43 147.3 11.3 2.2e-42 145.7 4.6 2.1 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Pkinase PF00069.25 EON96157.1 - 7.8e-43 146.7 0.0 2.2e-41 142.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON96157.1 - 1.4e-25 90.1 0.0 5.7e-25 88.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EON96157.1 - 0.013 14.3 0.3 0.022 13.6 0.3 1.4 1 1 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EON96157.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EON96157.1 - 0.051 12.9 0.4 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family AMPK1_CBM PF16561.5 EON96158.1 - 2.1e-26 91.9 0.0 3.7e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EON96158.1 - 1.6e-25 89.1 1.7 1.6e-25 89.1 1.7 2.4 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain DUF4663 PF15668.5 EON96158.1 - 0.19 10.8 0.0 0.19 10.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4663) Ras PF00071.22 EON96159.1 - 1.8e-29 102.4 0.5 7.9e-24 84.1 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 EON96159.1 - 0.0024 18.1 0.1 0.0063 16.7 0.1 1.7 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase HNOBA PF07701.14 EON96159.1 - 0.088 12.2 0.2 0.16 11.4 0.1 1.2 1 1 0 1 1 1 0 Heme NO binding associated Arf PF00025.21 EON96159.1 - 0.1 12.0 0.0 0.32 10.4 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EON96159.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 2 0 0 2 2 2 0 RsgA GTPase EF-hand_1 PF00036.32 EON96160.1 - 2.5e-27 92.3 12.5 2.2e-07 29.9 0.8 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EON96160.1 - 3.9e-23 81.7 6.6 2.7e-14 53.4 1.4 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EON96160.1 - 2.9e-20 70.4 7.7 4.2e-05 23.1 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EON96160.1 - 2.4e-18 64.7 11.8 1.6e-06 27.4 0.4 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 EON96160.1 - 1.1e-13 50.8 10.2 0.00012 21.8 0.5 4.2 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EON96160.1 - 5e-07 30.0 0.1 0.0012 19.1 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EON96160.1 - 2e-06 27.7 6.9 0.002 18.1 0.5 3.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EON96160.1 - 0.028 14.6 1.2 0.11 12.7 0.8 2.3 1 1 0 1 1 1 0 Dockerin type I domain TFIIE_alpha PF02002.17 EON96161.1 - 3.2e-18 65.5 0.1 6.1e-18 64.6 0.1 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit zf-FPG_IleRS PF06827.14 EON96161.1 - 0.071 13.0 1.4 5 7.1 0.1 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-CCHC_2 PF13696.6 EON96161.1 - 0.077 12.8 1.9 0.34 10.8 0.1 2.2 2 0 0 2 2 2 0 Zinc knuckle zinc-ribbons_6 PF07191.12 EON96161.1 - 0.083 12.9 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbons zf_UBZ PF18439.1 EON96161.1 - 0.13 11.9 1.4 11 5.7 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-Dof PF02701.15 EON96161.1 - 0.14 12.4 0.5 0.34 11.1 0.5 1.6 1 1 0 1 1 1 0 Dof domain, zinc finger Peptidase_S28 PF05577.12 EON96162.1 - 0.098 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 TPR_MLP1_2 PF07926.12 EON96163.1 - 0.076 13.1 0.9 0.22 11.6 0.1 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PPP5 PF08321.12 EON96164.1 - 8.3e-33 112.5 0.5 2.5e-32 111.0 0.1 2.0 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 EON96164.1 - 2.1e-32 113.3 0.1 3.1e-32 112.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 EON96164.1 - 3.4e-15 55.1 2.4 0.0018 18.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EON96164.1 - 2.7e-11 42.7 2.0 0.039 14.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EON96164.1 - 2e-08 33.8 6.3 0.00092 18.9 0.3 2.5 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 EON96164.1 - 5e-05 23.4 1.5 0.0041 17.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EON96164.1 - 0.00018 21.6 0.1 0.063 13.4 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EON96164.1 - 0.00028 20.8 1.5 1.4 9.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EON96164.1 - 0.016 15.7 1.0 16 6.1 0.0 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EON96164.1 - 0.035 14.9 0.1 14 6.9 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EON96164.1 - 0.46 11.2 4.2 4 8.2 0.3 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Fe_dep_repr_C PF02742.15 EON96165.1 - 1.5 9.0 4.6 0.41 10.7 0.9 2.1 2 1 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain Amidase PF01425.21 EON96166.1 - 1.8e-46 159.0 0.0 1.1e-43 149.9 0.0 2.1 2 0 0 2 2 2 2 Amidase ABC1 PF03109.16 EON96167.1 - 8.5e-33 113.0 0.0 1.6e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EON96167.1 - 0.0019 17.6 0.0 0.012 15.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain RRP36 PF06102.12 EON96168.1 - 8.2e-54 182.0 33.8 9.2e-54 181.9 33.8 1.0 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 BPL_N PF09825.9 EON96168.1 - 0.23 10.5 4.3 0.26 10.3 4.3 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal 7tm_2 PF00002.24 EON96169.1 - 0.00012 21.5 6.1 0.00012 21.5 6.1 1.9 2 1 0 2 2 2 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 EON96169.1 - 0.0021 17.4 8.8 0.0047 16.3 2.1 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 EON96169.1 - 0.14 11.5 8.8 0.24 10.7 8.8 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx DUF3455 PF11937.8 EON96170.1 - 2.8e-47 161.0 0.2 4e-47 160.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 EON96170.1 - 0.053 13.7 3.3 0.13 12.4 2.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2990) Pkinase PF00069.25 EON96171.1 - 2.1e-50 171.5 0.0 2.5e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON96171.1 - 2.6e-28 99.0 0.0 3.3e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EON96171.1 - 0.006 15.6 0.0 0.01 14.8 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EON96171.1 - 0.016 14.0 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EON96171.1 - 0.021 14.1 0.0 0.21 10.9 0.0 2.2 2 1 0 2 2 2 0 Kinase-like FAD_binding_3 PF01494.19 EON96172.1 - 1.2e-29 103.6 0.0 4.2e-29 101.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EON96172.1 - 1.8e-09 37.3 0.0 3.1e-07 30.0 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EON96172.1 - 1e-06 28.2 0.5 0.00018 20.8 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EON96172.1 - 3.4e-06 26.4 0.1 6.2e-05 22.2 0.3 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 EON96172.1 - 8.5e-06 25.6 0.1 2.2e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON96172.1 - 0.00012 21.3 0.6 0.011 14.9 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EON96172.1 - 0.00014 22.1 0.1 0.00032 20.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EON96172.1 - 0.0031 16.3 0.1 0.021 13.5 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EON96172.1 - 0.019 14.2 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EON96172.1 - 0.046 14.3 0.6 0.11 13.1 0.3 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EON96172.1 - 0.081 12.3 0.4 0.16 11.3 0.4 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EON96172.1 - 0.16 11.0 0.5 0.27 10.3 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 EON96172.1 - 0.23 11.3 0.1 0.38 10.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EON96172.1 - 0.23 11.4 0.6 13 5.7 0.7 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ribosomal_S9 PF00380.19 EON96173.1 - 2.9e-41 140.8 0.6 4.6e-41 140.1 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Adaptin_N PF01602.20 EON96174.1 - 2.1e-143 478.7 0.6 2.5e-143 478.4 0.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EON96174.1 - 1.3e-17 64.1 0.1 4e-17 62.5 0.1 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.6 EON96174.1 - 5e-07 30.0 1.5 0.029 14.7 0.0 4.5 3 2 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 EON96174.1 - 5.8e-07 29.7 7.0 0.00036 20.6 0.0 4.0 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF3730 PF12530.8 EON96174.1 - 4e-05 23.3 0.0 0.00027 20.6 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3730) HEAT PF02985.22 EON96174.1 - 0.0027 17.8 1.0 6.6 7.3 0.1 4.2 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 EON96174.1 - 0.019 15.5 0.4 26 5.4 0.0 4.4 3 1 1 4 4 4 0 HEAT-like repeat Cohesin_HEAT PF12765.7 EON96174.1 - 0.23 11.8 0.9 0.57 10.5 0.2 2.2 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion P5-ATPase PF12409.8 EON96175.1 - 8.4e-41 139.0 1.0 5.2e-40 136.4 0.0 2.4 2 0 0 2 2 2 1 P5-type ATPase cation transporter CMAS PF02353.20 EON96175.1 - 3.5e-35 121.6 0.7 6.6e-35 120.7 0.7 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase E1-E2_ATPase PF00122.20 EON96175.1 - 1.1e-28 100.0 0.1 1.2e-27 96.6 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Methyltransf_11 PF08241.12 EON96175.1 - 5.5e-16 59.0 0.0 1.5e-15 57.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON96175.1 - 1.8e-15 57.4 0.0 4.4e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON96175.1 - 4.6e-13 49.2 0.0 8.9e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Hydrolase PF00702.26 EON96175.1 - 4.8e-13 49.9 0.0 1.3e-05 25.6 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Methyltransf_12 PF08242.12 EON96175.1 - 5.9e-09 36.6 0.0 1.6e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON96175.1 - 1.9e-08 34.4 0.0 4.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cation_ATPase_C PF00689.21 EON96175.1 - 1.2e-07 31.7 4.7 3.2e-07 30.2 4.7 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Ubie_methyltran PF01209.18 EON96175.1 - 1.7e-06 27.5 0.0 3.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EON96175.1 - 5e-06 26.2 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.12 EON96175.1 - 0.0026 17.6 0.0 0.0077 16.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 EON96175.1 - 0.0026 17.2 0.0 0.0062 16.0 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.19 EON96175.1 - 0.0027 17.5 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cation_ATPase_N PF00690.26 EON96175.1 - 0.0037 16.9 0.0 0.0077 15.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EON96175.1 - 0.0081 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) TehB PF03848.14 EON96175.1 - 0.015 14.7 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF308 PF03729.13 EON96175.1 - 0.017 15.5 3.3 0.069 13.5 3.3 2.1 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) Methyltr_RsmB-F PF01189.17 EON96175.1 - 0.029 14.0 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F GidB PF02527.15 EON96175.1 - 0.062 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G FTO_CTD PF12934.7 EON96175.1 - 0.14 11.9 1.0 0.3 10.8 1.0 1.4 1 0 0 1 1 1 0 FTO C-terminal domain CBP_BcsF PF11120.8 EON96175.1 - 6.3 7.0 6.3 4.7 7.4 0.3 2.9 3 0 0 3 3 2 0 Cellulose biosynthesis protein BcsF DUF604 PF04646.12 EON96176.1 - 5.6e-12 45.6 0.1 3.8e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF604 Fringe PF02434.16 EON96176.1 - 2e-05 24.2 0.1 5e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 Fringe-like ETF PF01012.21 EON96176.1 - 0.055 13.4 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Electron transfer flavoprotein domain DUF3309 PF11752.8 EON96176.1 - 8.4 6.5 5.5 1.4 9.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) DUF640 PF04852.12 EON96177.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF640) Glyco_hydro_76 PF03663.14 EON96178.1 - 5.7e-39 134.7 30.0 7.8e-39 134.2 30.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EON96178.1 - 0.00045 19.4 10.3 0.014 14.5 0.0 3.1 1 1 2 3 3 3 3 Glycosyl Hydrolase Family 88 HPP PF04982.13 EON96178.1 - 0.036 14.3 0.2 0.094 12.9 0.2 1.8 1 0 0 1 1 1 0 HPP family MFS_1 PF07690.16 EON96179.1 - 4.1e-12 45.7 1.9 4.1e-12 45.7 1.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1211 PF06736.11 EON96179.1 - 0.51 10.8 6.3 5.4 7.5 0.7 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1211) DUF3821 PF12863.7 EON96180.1 - 0.013 15.4 0.3 0.024 14.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) Utp11 PF03998.13 EON96180.1 - 0.023 14.7 0.7 0.037 13.9 0.7 1.2 1 0 0 1 1 1 0 Utp11 protein Tom22 PF04281.13 EON96181.1 - 1.7e-48 163.9 0.2 1.9e-48 163.7 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Methyltransf_23 PF13489.6 EON96182.1 - 3.1e-08 33.6 0.0 5.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON96182.1 - 3e-05 23.9 0.0 4.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON96182.1 - 0.0041 17.8 0.0 0.0089 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON96182.1 - 0.13 13.0 0.0 0.46 11.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain ArAE_2_N PF10337.9 EON96183.1 - 5.2e-35 121.4 11.7 5.2e-35 121.4 11.7 3.9 2 1 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EON96183.1 - 4e-20 72.2 14.3 4e-20 72.2 14.3 3.1 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 EON96183.1 - 1.3e-10 41.5 0.0 4.9e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 EON96183.1 - 0.043 12.7 10.3 2.4 6.9 9.4 2.5 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF4211 PF13926.6 EON96184.1 - 4.8e-48 162.9 0.3 1.1e-46 158.4 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) CaM_bdg_C0 PF10562.9 EON96184.1 - 0.56 10.3 6.3 0.21 11.7 2.9 2.1 2 0 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit AXE1 PF05448.12 EON96185.1 - 0.0018 17.0 0.0 0.0054 15.4 0.0 1.6 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 EON96185.1 - 0.0096 15.4 0.0 0.019 14.4 0.0 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EON96185.1 - 0.19 11.2 0.1 0.39 10.1 0.1 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family OmpH PF03938.14 EON96186.1 - 1 9.7 8.4 2.1 8.7 8.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Aminotran_1_2 PF00155.21 EON96187.1 - 3e-60 204.3 0.0 3.6e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EON96187.1 - 0.017 14.1 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EON96187.1 - 0.074 11.6 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EON96187.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EON96187.1 - 0.15 11.3 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Zn_clus PF00172.18 EON96188.1 - 2.9e-07 30.5 12.1 4.7e-07 29.8 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SHOCT PF09851.9 EON96188.1 - 0.22 11.3 0.3 0.49 10.2 0.3 1.6 1 0 0 1 1 1 0 Short C-terminal domain CorA PF01544.18 EON96189.1 - 4.2e-14 52.5 0.1 6.6e-14 51.9 0.1 1.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Phage_holin_3_6 PF07332.11 EON96189.1 - 0.022 14.8 0.3 0.044 13.8 0.3 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4231 PF14015.6 EON96189.1 - 0.23 12.0 0.9 4 8.0 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) SAM_2 PF07647.17 EON96191.1 - 3.4e-16 59.1 0.0 6.4e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EON96191.1 - 1.1e-15 57.8 0.0 2.1e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EON96191.1 - 8.6e-10 39.1 0.0 1.8e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 EON96191.1 - 0.0045 16.9 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Dynamin_N PF00350.23 EON96192.1 - 1.4e-17 64.2 0.7 1.9e-16 60.5 0.0 2.4 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EON96192.1 - 2.9e-10 40.2 0.1 2.7e-09 37.1 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EON96192.1 - 4.4e-07 29.6 0.4 1.4e-05 24.8 0.4 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EON96192.1 - 0.0028 17.6 0.3 1.6 8.6 0.0 3.0 2 1 1 3 3 3 1 RsgA GTPase cobW PF02492.19 EON96192.1 - 0.0094 15.6 0.7 0.27 10.8 0.7 2.9 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PMEI PF04043.15 EON96192.1 - 0.038 14.3 0.1 0.089 13.1 0.1 1.6 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor AAA_18 PF13238.6 EON96192.1 - 0.048 14.2 0.4 0.26 11.8 0.0 2.5 4 0 0 4 4 2 0 AAA domain TsaE PF02367.17 EON96192.1 - 0.057 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FH2 PF02181.23 EON96192.1 - 0.064 12.4 1.9 0.06 12.5 0.5 1.6 2 0 0 2 2 2 0 Formin Homology 2 Domain DUF2408 PF10303.9 EON96192.1 - 0.066 13.8 2.6 0.13 12.8 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) AAA_29 PF13555.6 EON96192.1 - 0.096 12.5 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EON96192.1 - 0.1 12.9 0.1 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 EON96192.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain SKA1 PF07160.12 EON96192.1 - 0.39 10.5 4.3 0.49 10.2 0.3 2.4 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 FlaC_arch PF05377.11 EON96192.1 - 0.65 10.4 3.2 9.4 6.7 2.3 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Snf7 PF03357.21 EON96193.1 - 1.9e-37 128.6 17.6 4.4e-37 127.3 17.6 1.5 2 0 0 2 2 2 1 Snf7 HSCB_C PF07743.13 EON96193.1 - 0.011 16.2 2.1 0.011 16.2 2.1 2.9 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Ist1 PF03398.14 EON96193.1 - 0.031 14.2 7.5 0.05 13.5 7.5 1.3 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway RHH_8 PF17723.1 EON96193.1 - 0.16 12.1 4.7 0.57 10.4 0.1 2.5 1 1 2 3 3 3 0 Ribbon-Helix-Helix transcriptional regulator family Importin_rep_3 PF18806.1 EON96193.1 - 0.19 11.8 0.5 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Importin 13 repeat YojJ PF10372.9 EON96193.1 - 3.5 7.8 7.3 3.8 7.7 0.1 3.4 3 1 1 4 4 4 0 Bacterial membrane-spanning protein N-terminus zf-C2H2_4 PF13894.6 EON96195.1 - 6.8e-08 32.7 2.1 0.0042 17.8 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EON96195.1 - 1.7e-06 28.2 3.1 0.0073 16.7 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EON96195.1 - 0.11 12.5 1.3 1.5 8.9 0.4 2.3 1 1 1 2 2 2 0 C2H2-type zinc finger Ima1_N PF09779.9 EON96195.1 - 0.15 12.9 0.4 0.37 11.7 0.4 1.7 1 1 0 1 1 1 0 Ima1 N-terminal domain SesA PF17107.5 EON96196.1 - 7.9e-29 100.3 0.7 1e-28 100.0 0.7 1.1 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 EON96196.1 - 0.00051 19.5 0.1 0.00071 19.0 0.1 1.3 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins COG6 PF06419.11 EON96196.1 - 0.036 12.3 0.2 0.083 11.1 0.2 1.5 1 1 0 1 1 1 0 Conserved oligomeric complex COG6 DUF3567 PF12091.8 EON96196.1 - 0.054 13.6 0.2 15 5.8 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3567) AAA_16 PF13191.6 EON96196.1 - 0.054 13.9 0.4 0.76 10.1 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain DUF935 PF06074.12 EON96196.1 - 0.063 12.0 0.1 0.077 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Nbl1_Borealin_N PF10444.9 EON96196.1 - 0.092 12.4 0.1 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Rsa3 PF14615.6 EON96196.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 Ribosome-assembly protein 3 DivIC PF04977.15 EON96197.1 - 0.077 12.8 0.3 0.17 11.6 0.3 1.6 1 0 0 1 1 1 0 Septum formation initiator MFS_1 PF07690.16 EON96198.1 - 5.9e-44 150.4 43.5 5.9e-44 150.4 43.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EON96198.1 - 8.4e-14 50.9 26.0 1.2e-13 50.4 26.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Kinesin PF00225.23 EON96199.1 - 1.3e-116 389.1 0.0 1.8e-116 388.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EON96199.1 - 2.7e-27 95.5 0.5 7.6e-27 94.1 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding AAA_33 PF13671.6 EON96199.1 - 0.014 15.5 0.1 0.1 12.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain Herpes_UL14 PF03580.14 EON96199.1 - 0.018 15.3 2.0 0.048 13.9 2.0 1.8 1 0 0 1 1 1 0 Herpesvirus UL14-like protein AAA PF00004.29 EON96199.1 - 0.055 13.9 1.9 0.7 10.3 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Cation_efflux PF01545.21 EON96200.1 - 0.14 11.9 0.1 0.17 11.6 0.1 1.1 1 0 0 1 1 1 0 Cation efflux family p450 PF00067.22 EON96201.1 - 6.2e-42 143.9 0.0 1.7e-41 142.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 EON96201.1 - 1.6e-20 73.6 0.0 3.2e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON96201.1 - 3.7e-11 43.6 0.0 9.8e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON96201.1 - 6.7e-08 33.1 0.0 2.1e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON96201.1 - 1.3e-05 25.0 0.0 0.00027 20.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON96201.1 - 4e-05 24.3 0.0 0.00016 22.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON96201.1 - 0.0011 18.4 0.0 0.029 13.7 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EON96201.1 - 0.2 11.2 0.0 0.63 9.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain NRDD PF13597.6 EON96203.1 - 5.8e-175 583.3 0.0 7.4e-175 582.9 0.0 1.1 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase Radical_SAM PF04055.21 EON96203.1 - 4.9e-15 56.3 0.1 1.3e-14 55.0 0.1 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 EON96203.1 - 7.8e-09 35.7 0.0 2.6e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 EON96203.1 - 1e-06 29.1 0.0 3.4e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain PADR1 PF08063.12 EON96203.1 - 0.1 12.4 2.0 0.35 10.7 0.3 2.3 2 0 0 2 2 2 0 PADR1 (NUC008) domain Pentapeptide_4 PF13599.6 EON96204.1 - 0.0026 17.9 1.1 0.19 11.9 0.2 2.6 2 1 0 2 2 2 1 Pentapeptide repeats (9 copies) Beta_helix PF13229.6 EON96204.1 - 0.0051 16.7 9.1 0.29 11.0 9.4 2.1 1 1 0 1 1 1 1 Right handed beta helix region Pentapeptide PF00805.22 EON96204.1 - 0.099 12.3 1.2 1.8 8.3 0.0 3.1 4 0 0 4 4 4 0 Pentapeptide repeats (8 copies) CfAFP PF05264.11 EON96204.1 - 1.7 8.6 9.5 2.5 8.1 4.9 2.5 1 1 1 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) Acetyltransf_10 PF13673.7 EON96206.1 - 4.1e-08 33.2 0.0 5.4e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON96206.1 - 9.7e-08 32.3 0.0 2e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON96206.1 - 2.7e-05 24.5 0.0 3.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cation_ATPase_C PF00689.21 EON96207.1 - 1.1e-46 158.8 1.5 1.1e-46 158.8 1.5 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EON96207.1 - 6.4e-37 126.8 0.5 6.4e-37 126.8 0.5 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EON96207.1 - 4.6e-22 77.9 0.0 1e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EON96207.1 - 4.8e-19 69.5 0.9 1.5e-18 67.9 0.9 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EON96207.1 - 7.2e-08 32.0 0.0 4.4e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EON96207.1 - 2.6e-06 27.4 0.6 6.5e-05 22.8 0.6 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 EON96207.1 - 0.012 14.5 1.1 0.023 13.6 0.6 1.8 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Abhydrolase_9_N PF15420.6 EON96207.1 - 2.9 7.8 7.6 5.9 6.8 0.3 3.0 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus MFS_1 PF07690.16 EON96208.1 - 2.7e-18 66.0 34.7 2.7e-11 43.0 17.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AIRC PF00731.20 EON96210.1 - 1.6e-59 199.8 2.9 2.7e-59 199.0 1.8 2.1 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 EON96210.1 - 1.5e-50 171.1 0.1 3.7e-50 169.9 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain PurK_C PF17769.1 EON96210.1 - 4.7e-14 51.8 0.0 9.9e-14 50.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EON96210.1 - 1.8e-07 30.9 0.1 4.6e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus PrpR_N PF06506.11 EON96210.1 - 0.0053 16.4 0.4 0.16 11.6 0.0 2.5 2 0 0 2 2 2 1 Propionate catabolism activator XdhC_C PF13478.6 EON96210.1 - 0.0082 16.7 0.2 0.29 11.7 0.1 2.5 2 0 0 2 2 2 1 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 EON96210.1 - 0.017 14.5 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Siah-Interact_N PF09032.11 EON96210.1 - 0.15 12.4 0.5 0.55 10.6 0.0 2.1 2 0 0 2 2 2 0 Siah interacting protein, N terminal Sugar_tr PF00083.24 EON96211.1 - 3.9e-21 75.4 4.5 4.6e-21 75.2 4.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON96211.1 - 8.7e-17 61.1 5.2 1e-16 60.8 5.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EON96211.1 - 1.4e-06 27.0 0.3 1.6e-06 26.9 0.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EON96211.1 - 0.002 16.8 2.6 0.002 16.8 2.6 1.3 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 EON96211.1 - 0.0044 15.9 1.3 0.0051 15.7 1.3 1.1 1 0 0 1 1 1 1 MFS_1 like family Glyco_hydro_2_C PF02836.17 EON96212.1 - 3.6e-83 279.2 0.2 5.1e-83 278.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 EON96212.1 - 9.4e-37 126.5 0.1 1.7e-36 125.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 EON96212.1 - 6.8e-12 46.0 0.0 1.9e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 SKG6 PF08693.10 EON96213.1 - 3.7e-07 29.4 2.7 8.2e-07 28.3 2.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 EON96213.1 - 0.0053 15.7 4.3 0.0053 15.7 4.3 2.1 1 1 0 2 2 2 1 Giardia variant-specific surface protein MLANA PF14991.6 EON96213.1 - 0.015 15.6 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A DUF4448 PF14610.6 EON96213.1 - 0.074 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PTP_tm PF18861.1 EON96213.1 - 0.34 10.9 1.8 0.53 10.2 1.8 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Glyco_hydro_12 PF01670.16 EON96214.1 - 8.3e-24 84.8 5.7 6.1e-23 81.9 5.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 PetL PF05115.14 EON96214.1 - 0.17 11.9 0.6 0.39 10.7 0.6 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) MFS_1 PF07690.16 EON96216.1 - 1.7e-06 27.2 37.7 1e-05 24.7 35.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EON96216.1 - 7.7e-06 24.6 11.2 1e-05 24.2 11.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Antimicrobial_1 PF08018.11 EON96216.1 - 0.034 14.3 0.6 0.098 12.8 0.6 1.9 1 0 0 1 1 1 0 Frog antimicrobial peptide TauD PF02668.16 EON96217.1 - 1.8e-32 113.2 0.0 2.5e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1479 PF07350.12 EON96218.1 - 3.9e-125 417.9 0.0 4.4e-125 417.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Sugar_tr PF00083.24 EON96219.1 - 2.2e-12 46.6 0.3 2.4e-12 46.5 0.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter adh_short PF00106.25 EON96220.1 - 1.7e-18 66.8 0.0 2.5e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON96220.1 - 8e-13 48.5 0.0 1.6e-12 47.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EON96220.1 - 7.3e-07 29.3 0.0 1.4e-06 28.3 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EON96220.1 - 3e-05 23.6 0.0 5.3e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EON96220.1 - 0.00014 21.8 0.2 0.00024 21.1 0.2 1.3 1 0 0 1 1 1 1 KR domain Glyco_transf_9 PF01075.17 EON96220.1 - 0.0094 15.3 0.2 0.013 14.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Glyco_transf_4 PF13439.6 EON96220.1 - 0.057 13.4 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 DNA_pol_lambd_f PF10391.9 EON96220.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Preseq_ALAS PF09029.10 EON96221.1 - 0.0087 16.5 3.0 0.21 12.1 0.4 2.5 1 1 0 2 2 2 1 5-aminolevulinate synthase presequence DUF5423 PF17461.2 EON96221.1 - 0.17 10.7 0.1 0.26 10.1 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) PDR_CDR PF06422.12 EON96221.1 - 0.92 9.5 5.3 34 4.4 0.0 4.2 5 0 0 5 5 5 0 CDR ABC transporter DUF4512 PF14975.6 EON96221.1 - 3.2 8.6 6.1 18 6.2 0.4 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4512) zf-ANAPC11 PF12861.7 EON96221.1 - 3.2 7.9 5.7 0.71 10.0 0.9 2.5 2 2 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ribosomal_L14 PF00238.19 EON96222.1 - 2.9e-33 114.5 0.0 3.5e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e adh_short PF00106.25 EON96223.1 - 2.6e-38 131.5 0.5 6e-38 130.3 0.5 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON96223.1 - 1.1e-28 100.4 1.4 1.9e-28 99.6 1.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON96223.1 - 2.4e-12 47.1 0.4 4.8e-12 46.2 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EON96223.1 - 6.2e-07 29.1 0.1 1.3e-06 28.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EON96223.1 - 2.4e-05 23.9 1.0 0.00016 21.2 1.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EON96223.1 - 7.9e-05 22.6 2.3 0.00017 21.5 2.3 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EON96223.1 - 0.0023 18.2 0.8 0.006 16.9 0.3 1.9 1 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EON96223.1 - 0.04 14.5 1.3 0.088 13.4 1.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent p450 PF00067.22 EON96224.1 - 1e-55 189.3 0.0 2.8e-54 184.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF5427 PF10310.9 EON96225.1 - 1.4e-184 614.4 0.0 1.6e-184 614.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 EON96225.1 - 0.033 14.4 0.2 0.083 13.1 0.2 1.6 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain AflR PF08493.10 EON96225.1 - 0.037 13.5 0.5 0.057 12.9 0.5 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein SARAF PF06682.12 EON96225.1 - 1.1 8.8 5.3 2 8.0 5.3 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis MFS_1 PF07690.16 EON96226.1 - 3.9e-36 124.7 38.7 4.9e-36 124.4 38.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily NAD_binding_10 PF13460.6 EON96227.1 - 2.3e-26 92.8 0.3 3.1e-26 92.4 0.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EON96227.1 - 1.5e-08 34.4 0.0 1.7e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Vmethyltransf_C PF08456.10 EON96227.1 - 0.041 13.5 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Viral methyltransferase C-terminal DUF3818 PF12825.7 EON96228.1 - 2.7e-58 197.6 0.8 3.6e-37 128.2 0.2 2.3 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EON96228.1 - 2.1e-38 131.2 0.0 6.7e-38 129.6 0.0 1.9 2 0 0 2 2 2 1 PX-associated DUF3944 PF13099.6 EON96228.1 - 0.0039 17.0 0.1 0.0081 16.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3944) Sugar_tr PF00083.24 EON96229.1 - 1.2e-75 255.1 21.7 1.4e-75 254.9 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON96229.1 - 3e-28 98.8 27.1 4.6e-28 98.2 27.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EON96229.1 - 1.5e-07 30.2 5.1 1.2e-05 23.9 0.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EON96229.1 - 0.00014 20.6 27.5 0.0023 16.6 1.9 3.1 2 1 0 3 3 3 2 MFS/sugar transport protein 7tm_1 PF00001.21 EON96229.1 - 0.0052 16.2 1.1 0.011 15.0 1.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) WIYLD PF10440.9 EON96229.1 - 0.12 12.2 0.1 0.35 10.7 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain HET PF06985.11 EON96230.1 - 2.9e-36 125.0 0.0 4.8e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Caprin-1_dimer PF18293.1 EON96231.1 - 0.096 13.2 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Caprin-1 dimerization domain Aldolase_II PF00596.21 EON96233.1 - 4e-38 131.2 0.0 5e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Malic_M PF03949.15 EON96234.1 - 5.1e-89 297.9 0.0 8.5e-89 297.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EON96234.1 - 1.9e-66 223.3 0.0 3.1e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain AAA PF00004.29 EON96235.1 - 3.6e-16 59.8 0.0 6.7e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EON96235.1 - 0.082 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Glyco_tranf_2_3 PF13641.6 EON96236.1 - 9.8e-19 68.2 0.0 1.5e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EON96236.1 - 2.3e-17 63.6 0.1 2.3e-17 63.6 0.1 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EON96236.1 - 2.1e-14 53.7 0.0 3.6e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EON96236.1 - 4.6e-13 49.0 0.0 7.2e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 EON96236.1 - 1.1e-12 47.4 2.3 1.3e-09 37.2 0.5 3.0 1 1 2 3 3 3 2 Cellulose synthase Chitin_synth_2 PF03142.15 EON96236.1 - 0.019 13.6 0.1 0.19 10.3 0.0 2.2 2 0 0 2 2 2 0 Chitin synthase CDP-OH_P_transf PF01066.21 EON96237.1 - 0.085 13.6 0.0 0.17 12.7 0.0 1.5 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase ATG27 PF09451.10 EON96239.1 - 2.7e-99 332.3 0.0 3.3e-99 332.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EON96239.1 - 0.0027 17.8 0.0 0.8 9.8 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat adh_short PF00106.25 EON96240.1 - 9e-24 84.0 0.0 1.1e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON96240.1 - 5.5e-19 68.6 0.0 6.8e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TAF4 PF05236.14 EON96241.1 - 6.1e-28 98.4 8.2 1.3e-21 77.6 6.1 2.3 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family CDP-OH_P_transf PF01066.21 EON96242.1 - 1.8e-12 47.8 0.3 1.8e-12 47.8 0.3 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Ribonuc_red_lgC PF02867.15 EON96243.1 - 3e-193 643.1 0.0 3.8e-193 642.8 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EON96243.1 - 2.4e-24 85.2 0.0 5.4e-24 84.0 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EON96243.1 - 1e-13 51.6 0.0 2.2e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain VWA PF00092.28 EON96245.1 - 2e-07 31.4 0.0 5.8e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EON96245.1 - 6.3e-05 23.6 0.0 0.00018 22.1 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Aminotran_3 PF00202.21 EON96246.1 - 4.5e-109 364.8 0.0 5.6e-109 364.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EON96248.1 - 1.7e-31 109.7 0.0 5.5e-30 104.8 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II CPSF73-100_C PF11718.8 EON96249.1 - 1.4e-87 292.8 0.1 2e-87 292.3 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EON96249.1 - 1.2e-30 106.0 0.0 2.7e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 EON96249.1 - 1.5e-13 50.5 0.0 2.9e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 EON96249.1 - 5.2e-12 45.6 0.1 1.3e-11 44.3 0.1 1.7 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EON96249.1 - 1.9e-05 24.8 0.1 0.12 12.4 0.0 2.5 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 EON96249.1 - 0.0019 18.1 0.1 0.0019 18.1 0.1 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain CHB_HEX_C PF03174.13 EON96249.1 - 0.15 12.1 0.0 1.2 9.2 0.0 2.5 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain Beta_lactamase3 PF17030.5 EON96249.1 - 0.16 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative beta-lactamase-like family A_deaminase PF00962.22 EON96250.1 - 1.2e-75 254.9 0.0 1.4e-75 254.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Apolipoprotein PF01442.18 EON96251.1 - 3.2e-05 23.9 0.8 3.2e-05 23.9 0.8 8.0 4 4 2 6 6 6 1 Apolipoprotein A1/A4/E domain Inhibitor_I34 PF10466.9 EON96251.1 - 0.45 11.2 2.8 1 10.0 0.2 3.1 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 NPV_P10 PF05531.12 EON96251.1 - 2.5 8.6 23.6 4.5 7.8 0.1 7.7 3 2 2 6 6 6 0 Nucleopolyhedrovirus P10 protein Pyridoxal_deC PF00282.19 EON96253.1 - 3.1e-71 240.1 0.0 7.3e-71 238.9 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Lyase_1 PF00206.20 EON96254.1 - 0.049 13.0 0.2 0.078 12.4 0.2 1.2 1 0 0 1 1 1 0 Lyase LRR_4 PF12799.7 EON96255.1 - 2.5e-32 110.4 30.2 4.9e-06 26.8 2.8 8.4 6 2 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EON96255.1 - 5e-27 93.4 29.3 5.1e-09 35.8 3.6 6.0 5 1 2 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 EON96255.1 - 2.9e-10 39.9 20.4 0.0054 16.3 4.1 5.8 1 1 5 6 6 6 6 Leucine-rich repeat LRR_6 PF13516.6 EON96255.1 - 1e-06 28.3 27.8 1.9 8.7 0.1 10.0 10 0 0 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.33 EON96255.1 - 4.1e-05 23.6 31.7 14 6.7 0.1 11.0 10 2 0 10 10 10 3 Leucine Rich Repeat Adaptin_N PF01602.20 EON96256.1 - 7.5e-117 391.0 8.2 9.2e-117 390.8 8.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EON96256.1 - 1.9e-47 160.1 0.0 5.3e-47 158.7 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EON96256.1 - 8.2e-15 55.1 0.0 1.5e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Xpo1 PF08389.12 EON96256.1 - 0.42 10.7 2.5 3.7 7.6 0.1 3.0 3 0 0 3 3 3 0 Exportin 1-like protein Clathrin PF00637.20 EON96257.1 - 6e-25 87.8 5.2 2.9e-23 82.3 0.9 3.3 2 1 1 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.8 EON96257.1 - 2.1e-22 79.1 0.2 5.7e-22 77.7 0.2 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EON96257.1 - 1.8e-06 27.9 5.6 3.5e-06 26.9 5.6 1.5 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 EON96257.1 - 0.00012 21.9 4.9 0.00026 20.8 4.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.6 EON96257.1 - 0.00027 20.5 0.6 0.00063 19.4 0.1 2.0 2 0 0 2 2 1 1 TPR repeat zf-RING_5 PF14634.6 EON96257.1 - 0.0022 17.9 4.9 0.0043 17.0 4.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_14 PF13428.6 EON96257.1 - 0.0059 17.3 0.1 9.7 7.3 0.0 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 EON96257.1 - 0.0065 16.8 4.5 0.016 15.5 4.5 1.7 1 0 0 1 1 1 1 Ring finger domain DUF4810 PF16068.5 EON96257.1 - 0.029 14.9 1.1 17 6.0 0.1 3.4 3 0 0 3 3 2 0 Domain of unknown function (DUF4810) ANAPC3 PF12895.7 EON96257.1 - 0.03 14.5 4.7 2.8 8.2 0.2 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-RING_UBOX PF13445.6 EON96257.1 - 0.035 14.1 4.2 0.093 12.8 4.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 EON96257.1 - 0.074 13.4 3.3 0.16 12.3 3.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain WD40 PF00400.32 EON96257.1 - 0.13 13.2 0.5 7.7 7.6 0.1 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-C3HC4 PF00097.25 EON96257.1 - 0.14 12.1 3.1 0.32 10.9 3.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EON96257.1 - 0.14 12.2 2.3 0.32 11.1 2.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_2 PF07719.17 EON96257.1 - 0.27 11.5 3.7 0.74 10.1 0.0 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EON96257.1 - 0.85 10.2 4.9 3.3 8.3 0.6 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EON96257.1 - 1.5 9.2 5.4 2.7 8.3 0.3 3.2 3 1 0 3 3 2 0 Tetratricopeptide repeat zf-RING_10 PF16685.5 EON96257.1 - 1.7 8.8 5.7 2.9 8.1 2.8 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 TPR_8 PF13181.6 EON96257.1 - 2.7 8.4 5.3 3 8.3 0.1 3.6 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 EON96257.1 - 3.6 7.7 6.0 10 6.2 1.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Het-C PF07217.11 EON96259.1 - 2.2e-285 947.6 0.0 2.7e-285 947.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C SET PF00856.28 EON96260.1 - 0.021 15.2 0.0 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 SET domain P16-Arc PF04699.14 EON96262.1 - 1.9e-32 112.8 0.0 2.3e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) TFIID-18kDa PF02269.16 EON96263.1 - 1.1e-17 63.8 0.0 1.5e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EON96263.1 - 0.0018 18.2 0.0 0.003 17.5 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 EON96263.1 - 0.0052 17.1 0.0 0.0087 16.4 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EON96263.1 - 0.0064 16.6 0.0 0.0087 16.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EON96263.1 - 0.0064 16.8 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EON96263.1 - 0.11 12.9 0.1 0.24 11.8 0.0 1.6 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 PARP PF00644.20 EON96264.1 - 3.5e-14 52.9 0.0 6.7e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 EON96264.1 - 8e-07 28.8 0.0 1.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Spt20 PF12090.8 EON96265.1 - 3e-05 23.8 0.3 3e-05 23.8 0.3 7.4 3 1 3 6 6 6 2 Spt20 family GEN1_C PF18380.1 EON96266.1 - 1.1e-29 103.3 0.0 4e-29 101.6 0.0 2.0 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 EON96266.1 - 5.8e-26 90.7 0.0 2e-25 88.9 0.0 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EON96266.1 - 4.3e-08 33.6 0.0 1e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain PP2C PF00481.21 EON96268.1 - 4.8e-38 131.3 0.0 6.3e-32 111.2 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EON96268.1 - 0.0012 18.6 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C RRM_1 PF00076.22 EON96269.1 - 9e-41 137.5 0.8 1.9e-19 69.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EON96269.1 - 1.2e-23 84.0 0.2 4.4e-23 82.2 0.2 2.1 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 EON96269.1 - 0.002 18.0 0.0 0.34 10.8 0.0 3.2 3 1 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EON96269.1 - 0.0037 17.3 2.6 0.15 12.2 0.0 3.3 3 2 1 4 4 4 1 RNA binding motif RRM_5 PF13893.6 EON96269.1 - 0.014 15.0 0.0 0.041 13.5 0.0 1.8 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 EON96269.1 - 0.022 14.6 0.2 15 5.4 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF1866) RRM_7 PF16367.5 EON96269.1 - 0.031 14.4 0.0 2.2 8.5 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif DUF4078 PF13300.6 EON96269.1 - 0.13 12.6 2.4 41 4.6 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4078) Ala_racemase_N PF01168.20 EON96270.1 - 4.9e-23 81.9 0.1 5.6e-23 81.7 0.1 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain tRNA-synt_2b PF00587.25 EON96271.1 - 1.6e-20 73.8 0.0 2.7e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EON96271.1 - 3.8e-09 36.8 3.0 1.6e-08 34.8 3.0 1.9 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Methyltransf_11 PF08241.12 EON96272.1 - 9e-10 39.1 0.0 1.5e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON96272.1 - 8.2e-09 35.5 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON96272.1 - 5.4e-06 27.0 0.0 9.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON96272.1 - 1.4e-05 25.8 0.0 2.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON96272.1 - 0.0001 22.1 0.0 0.00024 20.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON96272.1 - 0.0048 16.3 0.0 0.012 14.9 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_7 PF03492.15 EON96272.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase DLH PF01738.18 EON96273.1 - 2.1e-10 40.5 0.0 2.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family SWIB PF02201.18 EON96274.1 - 9.2e-23 79.9 0.0 1.7e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Mito_carr PF00153.27 EON96275.1 - 1.3e-42 143.6 10.1 2.8e-16 59.2 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HTH_38 PF13936.6 EON96276.1 - 1.8e-07 30.8 1.4 0.00071 19.3 0.1 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_24 PF13412.6 EON96276.1 - 5.9e-06 25.8 5.7 0.0017 17.9 0.1 3.1 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_32 PF13565.6 EON96276.1 - 9e-06 26.2 2.6 0.0011 19.6 1.2 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 EON96276.1 - 5.5e-05 22.8 0.4 0.019 14.8 0.0 2.8 2 1 1 3 3 3 1 Homeodomain-like domain MarR_2 PF12802.7 EON96276.1 - 0.0004 20.2 2.4 0.71 9.8 0.9 3.1 2 1 0 2 2 2 2 MarR family HTH_5 PF01022.20 EON96276.1 - 0.00057 19.7 0.3 0.16 11.9 0.3 2.7 2 1 0 2 2 2 1 Bacterial regulatory protein, arsR family PAX PF00292.18 EON96276.1 - 0.00079 19.4 0.0 0.0059 16.5 0.0 1.9 1 1 1 2 2 2 1 'Paired box' domain HTH_AsnC-type PF13404.6 EON96276.1 - 0.0015 18.3 0.1 0.0015 18.3 0.1 2.3 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain MarR PF01047.22 EON96276.1 - 0.003 17.4 2.3 2.5 8.1 0.0 3.3 2 1 0 2 2 2 1 MarR family GerE PF00196.19 EON96276.1 - 0.0035 16.8 0.1 0.13 11.8 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EON96276.1 - 0.0052 16.4 0.0 0.18 11.5 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON96276.1 - 0.0056 16.2 2.3 0.13 11.8 0.3 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_29 PF13551.6 EON96276.1 - 0.0075 16.3 2.0 0.44 10.6 0.1 3.0 3 0 0 3 3 3 1 Winged helix-turn helix HTH_28 PF13518.6 EON96276.1 - 0.012 15.7 0.1 0.092 12.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain YhdB PF14148.6 EON96276.1 - 0.06 13.5 0.3 0.094 12.8 0.3 1.3 1 0 0 1 1 1 0 YhdB-like protein HTH_Tnp_ISL3 PF13542.6 EON96276.1 - 0.09 12.2 0.0 14 5.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Mg_chelatase_C PF13335.6 EON96276.1 - 0.11 13.2 2.3 1.5 9.5 0.0 2.7 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal HTH_11 PF08279.12 EON96276.1 - 0.35 10.9 5.1 6.8 6.7 2.1 3.0 2 1 0 2 2 2 0 HTH domain Sfi1 PF08457.10 EON96277.1 - 1.3e-35 123.0 27.5 1.6e-35 122.7 27.5 1.0 1 0 0 1 1 1 1 Sfi1 spindle body protein V_ATPase_I PF01496.19 EON96278.1 - 0 1042.0 0.1 0 1041.8 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TMEM174 PF15029.6 EON96278.1 - 0.13 12.0 1.3 0.24 11.1 1.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 174 Nup54 PF13874.6 EON96278.1 - 0.25 11.4 2.2 3.3 7.8 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 CheZ PF04344.13 EON96278.1 - 0.31 10.9 2.7 0.67 9.8 0.1 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ DivIC PF04977.15 EON96278.1 - 1.3 8.8 4.0 1.4 8.7 0.0 2.9 3 0 0 3 3 3 0 Septum formation initiator ATP-synt_Eps PF04627.13 EON96279.1 - 1.2e-21 76.4 0.2 1.2e-21 76.4 0.2 1.4 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Tcp11 PF05794.13 EON96280.1 - 1.7e-93 314.1 0.0 2.4e-93 313.6 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 Alpha-amylase PF00128.24 EON96281.1 - 1.1e-22 81.0 3.3 3.8e-22 79.3 3.3 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 EON96281.1 - 1.4e-07 30.2 1.6 0.012 13.8 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 EON96281.1 - 0.0017 18.5 0.1 0.0068 16.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1939) Hexapep PF00132.24 EON96283.1 - 2.6e-07 30.1 0.8 0.0029 17.3 0.1 3.4 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EON96283.1 - 7.2e-05 21.9 1.5 0.00019 20.5 1.5 1.6 1 1 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 EON96283.1 - 0.0003 19.1 0.4 0.0026 16.0 0.5 1.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EON96283.1 - 0.055 13.2 3.9 3.1 7.6 0.1 3.2 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase OMPdecase PF00215.24 EON96284.1 - 5e-101 337.0 0.0 6.2e-101 336.7 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Uds1 PF15456.6 EON96285.1 - 3e-42 143.9 7.7 3e-42 143.9 7.7 6.6 3 1 3 6 6 6 1 Up-regulated During Septation TMF_DNA_bd PF12329.8 EON96285.1 - 0.0058 16.6 8.9 0.0058 16.6 8.9 9.1 7 1 4 11 11 11 2 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 EON96285.1 - 0.011 16.2 16.7 0.011 16.2 16.7 6.1 2 1 3 6 6 6 0 Fez1 CENP-F_C_Rb_bdg PF10490.9 EON96285.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Img2 PF05046.14 EON96285.1 - 0.57 10.5 3.8 1.4 9.3 0.1 3.4 3 0 0 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) DUF1098 PF06497.11 EON96285.1 - 0.92 10.0 3.6 2.7 8.5 3.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1098) Dynactin PF12455.8 EON96286.1 - 4.6e-113 377.2 9.9 4.6e-113 377.2 9.9 3.4 5 0 0 5 5 5 1 Dynein associated protein DUF3138 PF11336.8 EON96286.1 - 0.6 8.7 3.6 1.5 7.3 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MHC_II_beta PF00969.19 EON96286.1 - 1 9.5 3.2 20 5.4 0.1 3.3 3 0 0 3 3 3 0 Class II histocompatibility antigen, beta domain DUF2443 PF10398.9 EON96286.1 - 3.3 7.8 8.9 0.54 10.3 0.3 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2443) MAD PF05557.13 EON96286.1 - 4.4 5.5 77.3 1 7.7 12.5 4.9 2 2 2 4 4 4 0 Mitotic checkpoint protein TatD_DNase PF01026.21 EON96287.1 - 8.2e-50 169.5 0.3 1.7e-49 168.5 0.3 1.5 1 1 0 1 1 1 1 TatD related DNase Coilin_N PF15862.5 EON96287.1 - 0.1 12.4 0.3 0.45 10.3 0.1 1.9 2 0 0 2 2 2 0 Coilin N-terminus tRNA-synt_1 PF00133.22 EON96288.1 - 1.1e-220 734.0 0.0 1.6e-220 733.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EON96288.1 - 1.5e-25 89.9 0.0 7.1e-25 87.7 0.0 2.1 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EON96288.1 - 3.1e-14 52.5 0.0 9.8e-05 21.3 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EON96288.1 - 0.0096 15.3 0.0 0.038 13.3 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 EON96288.1 - 0.054 13.0 0.2 0.12 11.8 0.2 1.6 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 CFEM PF05730.11 EON96291.1 - 3.8e-13 49.3 8.0 6.8e-13 48.5 8.0 1.4 1 0 0 1 1 1 1 CFEM domain Ribosomal_L26 PF16906.5 EON96292.1 - 7.2e-39 132.1 3.4 9.3e-39 131.8 3.4 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EON96292.1 - 5.1e-07 29.4 1.1 1.6e-06 27.9 1.1 1.8 1 0 0 1 1 1 1 KOW motif bZIP_2 PF07716.15 EON96293.1 - 1.7e-11 44.0 12.2 3e-11 43.2 12.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EON96293.1 - 0.011 15.9 10.5 0.02 15.0 10.5 1.5 1 0 0 1 1 1 0 bZIP transcription factor GIT_CC PF16559.5 EON96293.1 - 0.018 14.9 2.8 0.043 13.7 2.8 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor XhlA PF10779.9 EON96293.1 - 0.022 15.0 4.0 0.022 15.0 4.0 1.8 2 0 0 2 2 2 0 Haemolysin XhlA LCD1 PF09798.9 EON96293.1 - 0.027 13.0 3.1 0.031 12.8 3.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein TSC22 PF01166.18 EON96293.1 - 0.082 13.2 1.2 0.19 12.0 1.2 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 EON96293.1 - 0.091 12.6 1.7 0.17 11.7 1.7 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region APC_u14 PF16635.5 EON96293.1 - 0.67 10.5 7.3 0.071 13.7 1.9 2.1 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr bZIP_1 PF00170.21 EON96294.1 - 4.3e-09 36.3 7.7 9.3e-09 35.3 7.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EON96294.1 - 0.0016 18.5 8.4 0.0016 18.5 8.4 2.3 2 0 0 2 2 2 1 Basic region leucine zipper DivIC PF04977.15 EON96294.1 - 3.1 7.6 11.1 1.5 8.6 0.3 2.5 2 0 0 2 2 2 0 Septum formation initiator ECH_1 PF00378.20 EON96295.1 - 2.4e-18 66.4 0.0 3.1e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON96295.1 - 1.8e-08 34.3 0.0 2.1e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EON96295.1 - 0.0048 16.9 0.0 2.1 8.3 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 ING PF12998.7 EON96296.1 - 1.5e-09 38.3 0.0 2.9e-05 24.6 0.0 2.6 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EON96296.1 - 2.7e-06 27.2 8.0 4.5e-06 26.5 8.0 1.4 1 0 0 1 1 1 1 PHD-finger Orbi_VP5 PF00901.17 EON96296.1 - 0.011 14.2 0.6 0.015 13.7 0.6 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 zf-HC5HC2H PF13771.6 EON96296.1 - 0.014 15.6 2.5 0.032 14.5 2.5 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PBP1_TM PF14812.6 EON96296.1 - 0.42 11.0 4.0 6.6 7.2 1.6 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_M16 PF00675.20 EON96297.1 - 4.9e-17 62.3 0.1 8.9e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EON96297.1 - 5.4e-16 59.1 0.0 1e-15 58.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain MscS_porin PF12795.7 EON96298.1 - 0.0035 16.9 7.8 0.0058 16.2 7.8 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain SKA1 PF07160.12 EON96298.1 - 0.061 13.2 1.8 0.094 12.6 1.8 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Replicase PF03090.17 EON96298.1 - 0.083 12.7 0.0 0.32 10.8 0.0 1.9 1 1 1 2 2 2 0 Replicase family Spc7 PF08317.11 EON96298.1 - 0.11 11.4 9.1 0.24 10.3 9.1 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 EON96298.1 - 0.37 11.0 4.3 0.76 9.9 4.3 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Nsp1_C PF05064.13 EON96298.1 - 0.38 10.6 7.4 0.73 9.7 6.9 1.7 1 1 0 1 1 1 0 Nsp1-like C-terminal region Golgin_A5 PF09787.9 EON96298.1 - 0.48 9.8 9.3 1.1 8.6 9.3 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 Seryl_tRNA_N PF02403.22 EON96298.1 - 1 9.6 6.0 0.36 11.1 1.8 2.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Sec2p PF06428.11 EON96298.1 - 1.1 9.2 13.7 6.7 6.8 8.0 2.5 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Spc24 PF08286.11 EON96298.1 - 5.7 7.2 7.3 17 5.7 7.3 1.9 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 FTR1 PF03239.14 EON96299.1 - 6.2e-79 265.3 10.3 7.3e-79 265.1 10.3 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Comm PF15957.5 EON96299.1 - 0.088 13.2 0.3 5.2 7.4 0.0 2.7 2 0 0 2 2 2 0 Commissureless DUF5363 PF17320.2 EON96299.1 - 0.17 11.8 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5363) Ferlin_C PF16165.5 EON96299.1 - 0.21 11.5 0.7 0.56 10.1 0.0 2.1 2 0 0 2 2 2 0 Ferlin C-terminus Mak10 PF04112.13 EON96300.1 - 7.4e-26 90.7 0.0 9.9e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase TIP49 PF06068.13 EON96301.1 - 3.2e-166 552.8 0.1 3.9e-166 552.5 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EON96301.1 - 1.2e-23 83.0 0.1 3.6e-23 81.5 0.1 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EON96301.1 - 2.9e-11 43.9 0.2 8.7e-07 29.4 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EON96301.1 - 1.1e-09 38.2 0.2 6.8e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EON96301.1 - 7.7e-05 23.0 0.2 0.082 13.2 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EON96301.1 - 0.00054 20.3 2.0 0.11 12.8 0.2 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EON96301.1 - 0.00062 20.2 0.1 0.0059 17.0 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 EON96301.1 - 0.00089 19.5 0.1 0.0025 18.1 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EON96301.1 - 0.0031 17.5 0.1 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EON96301.1 - 0.0091 15.4 0.2 0.38 10.1 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EON96301.1 - 0.01 16.4 0.0 0.03 14.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EON96301.1 - 0.011 15.3 0.2 0.068 12.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EON96301.1 - 0.014 15.1 0.1 1.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EON96301.1 - 0.023 13.9 0.2 0.062 12.6 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin DnaB_C PF03796.15 EON96301.1 - 0.025 13.9 0.0 0.073 12.4 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 EON96301.1 - 0.032 14.0 0.1 0.066 12.9 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EON96301.1 - 0.05 13.3 0.2 3.2 7.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EON96301.1 - 0.055 12.7 0.1 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TFIID-31kDa PF02291.15 EON96301.1 - 0.16 12.0 0.0 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Cupin_2 PF07883.11 EON96302.1 - 2.7e-07 30.2 0.0 5.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Ribosomal_L2_C PF03947.18 EON96302.1 - 0.0044 17.2 0.0 0.006 16.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Cupin_1 PF00190.22 EON96302.1 - 0.043 13.4 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 EON96302.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) CN_hydrolase PF00795.22 EON96303.1 - 5.8e-36 124.2 0.0 3.5e-31 108.5 0.0 2.2 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase Anophelin PF10731.9 EON96304.1 - 1.6 8.6 6.3 0.85 9.5 1.4 2.8 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito RTA1 PF04479.13 EON96305.1 - 1e-11 44.9 0.1 1.5e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4096 PF13340.6 EON96305.1 - 0.0019 18.4 0.0 0.63 10.3 0.0 2.4 1 1 1 2 2 2 2 Putative transposase of IS4/5 family (DUF4096) Cu-oxidase_2 PF07731.14 EON96306.1 - 4.6e-42 143.0 1.0 5.5e-38 129.8 0.2 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EON96306.1 - 1.7e-39 135.5 0.2 4.6e-36 124.3 0.1 2.9 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EON96306.1 - 1.3e-23 83.2 1.6 1.2e-19 70.4 0.3 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 EON96306.1 - 0.00076 19.6 0.0 12 6.1 0.0 3.6 3 0 0 3 3 3 2 Cupredoxin-like domain Pkinase PF00069.25 EON96307.1 - 3.4e-50 170.9 0.0 6.2e-34 117.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EON96307.1 - 2.3e-21 76.2 0.1 1.5e-19 70.3 0.1 3.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EON96307.1 - 0.00012 21.5 0.0 0.00044 19.6 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EON96307.1 - 0.00038 20.5 0.2 0.0048 16.8 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Mito_carr PF00153.27 EON96308.1 - 2.8e-30 104.1 0.5 2e-15 56.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.18 EON96309.1 - 2.8e-07 30.5 12.6 4.6e-07 29.8 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EON96309.1 - 6.9e-07 28.6 0.0 1.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain LRR_6 PF13516.6 EON96310.1 - 0.0034 17.3 0.1 15 5.9 0.0 4.6 4 0 0 4 4 4 1 Leucine Rich repeat F-box-like PF12937.7 EON96310.1 - 0.0086 15.9 0.4 0.029 14.2 0.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EON96310.1 - 0.13 12.7 2.1 3.8 8.1 0.0 4.1 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Glycos_transf_1 PF00534.20 EON96311.1 - 8e-34 116.6 0.0 2.6e-32 111.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EON96311.1 - 2.2e-18 66.8 0.0 3.7e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EON96311.1 - 2.7e-16 60.2 0.4 6.5e-16 59.0 0.4 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EON96311.1 - 1.2e-07 32.3 12.0 1.5e-07 32.0 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 EON96311.1 - 7.2e-05 22.9 0.2 0.064 13.3 0.0 2.5 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus Glyco_trans_1_2 PF13524.6 EON96311.1 - 0.0011 19.3 0.0 0.0027 18.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DOCK_N PF16172.5 EON96312.1 - 1.4e-128 429.0 0.0 2.4e-128 428.3 0.0 1.4 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 EON96312.1 - 1.6e-36 126.0 0.0 3.1e-36 125.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 EON96312.1 - 1.5e-30 106.4 3.3 7.4e-30 104.1 3.3 2.0 1 1 0 1 1 1 1 Dock homology region 2 SH3_1 PF00018.28 EON96312.1 - 7.4e-06 25.5 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EON96312.1 - 0.00029 20.6 0.1 0.00096 19.0 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain ScsC_N PF18312.1 EON96312.1 - 0.022 14.6 0.1 0.071 12.9 0.1 2.0 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain SH3_2 PF07653.17 EON96312.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.8 1 1 0 1 1 1 0 Variant SH3 domain Mito_carr PF00153.27 EON96313.1 - 2.6e-51 171.5 4.6 9.9e-17 60.7 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.16 EON96313.1 - 0.075 13.0 0.1 0.24 11.4 0.1 1.9 1 0 0 1 1 1 0 UcrQ family Abhydrolase_3 PF07859.13 EON96314.1 - 1e-34 120.3 0.0 2.2e-24 86.5 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EON96314.1 - 0.057 12.3 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Lipase_3 PF01764.25 EON96314.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) SRP19 PF01922.17 EON96315.1 - 1e-33 116.1 0.0 1.7e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein RNA_pol_Rpc82 PF05645.13 EON96316.1 - 3.3e-46 158.2 0.0 1.4e-45 156.0 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 EON96316.1 - 5.5e-19 68.0 0.1 3.6e-18 65.4 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 EON96316.1 - 7e-05 22.6 2.0 0.022 14.6 0.0 3.7 3 1 1 4 4 4 2 TFIIE alpha subunit zf-C2H2 PF00096.26 EON96317.1 - 2.5e-06 27.6 14.1 0.0099 16.3 2.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EON96317.1 - 0.023 15.5 10.6 1.3 10.0 2.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EON96317.1 - 0.039 14.4 4.0 0.039 14.4 4.0 2.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.15 EON96317.1 - 0.23 11.5 3.8 0.23 11.5 2.3 1.8 1 1 1 2 2 2 0 BED zinc finger MFS_1 PF07690.16 EON96318.1 - 2e-15 56.6 28.4 2e-15 56.6 28.4 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 EON96318.1 - 0.00016 21.3 5.0 0.00016 21.3 5.0 2.6 2 1 0 2 2 2 1 Nodulin-like HKR_ArcB_TM PF18415.1 EON96318.1 - 5.3 7.9 8.9 1.3 9.9 0.9 3.4 3 0 0 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain Mo25 PF08569.11 EON96319.1 - 2e-122 408.7 0.0 2.4e-122 408.4 0.0 1.0 1 0 0 1 1 1 1 Mo25-like Cyt-b5 PF00173.28 EON96321.1 - 2.2e-18 66.1 2.1 2.8e-18 65.8 0.2 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EON96321.1 - 4.2e-12 46.5 18.7 8.7e-12 45.5 18.7 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 EON96321.1 - 0.0043 17.3 0.1 0.01 16.0 0.0 1.6 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region COX14 PF14880.6 EON96321.1 - 0.042 13.7 1.3 0.054 13.4 0.2 1.8 2 0 0 2 2 2 0 Cytochrome oxidase c assembly MS_channel PF00924.18 EON96322.1 - 9.8e-19 67.7 2.7 2.3e-18 66.5 2.7 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.6 EON96322.1 - 0.0076 16.7 0.0 0.024 15.1 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EON96322.1 - 0.019 14.5 0.3 0.019 14.5 0.3 2.0 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 EON96322.1 - 0.02 14.4 0.1 0.02 14.4 0.1 2.0 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 EON96322.1 - 0.058 13.4 0.0 0.27 11.3 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain Bac_export_2 PF01312.19 EON96322.1 - 3.7 6.7 5.2 7.9 5.6 0.2 2.3 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family Chorismate_synt PF01264.21 EON96323.1 - 1.4e-139 464.4 0.0 1.6e-139 464.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Glyco_hydro_12 PF01670.16 EON96324.1 - 1e-46 159.6 14.2 1.2e-46 159.4 14.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Phage_holin_5_1 PF06946.11 EON96324.1 - 1.9 8.9 7.0 0.34 11.3 1.1 2.4 1 1 1 2 2 2 0 Bacteriophage A118-like holin, Hol118 HALZ PF02183.18 EON96325.1 - 0.11 12.8 1.0 0.11 12.8 1.0 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Jnk-SapK_ap_N PF09744.9 EON96325.1 - 0.22 11.7 9.9 0.21 11.8 3.4 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 G-gamma PF00631.22 EON96325.1 - 0.23 11.5 2.5 12 6.0 0.1 2.7 2 0 0 2 2 2 0 GGL domain SlyX PF04102.12 EON96325.1 - 0.6 10.8 5.7 3.6 8.3 0.1 3.4 3 1 0 3 3 3 0 SlyX DUF1192 PF06698.11 EON96325.1 - 5.5 7.1 11.1 19 5.4 2.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) zinc_ribbon_15 PF17032.5 EON96327.1 - 0.19 12.5 5.9 1.1 10.1 1.0 2.9 2 2 1 3 3 3 0 zinc-ribbon family DZR PF12773.7 EON96327.1 - 1 9.4 7.2 3.9 7.6 0.1 3.5 3 1 0 3 3 3 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 EON96327.1 - 8.4 6.4 8.1 25 4.9 0.2 3.6 4 0 0 4 4 4 0 Putative transposase DNA-binding domain Glyco_hydro_28 PF00295.17 EON96328.1 - 8e-10 38.3 1.9 1.7e-09 37.2 1.9 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 EON96328.1 - 0.00071 19.5 3.8 0.00071 19.5 3.8 2.9 1 1 1 2 2 2 2 Right handed beta helix region OstA_2 PF13100.6 EON96328.1 - 0.045 13.3 0.0 0.71 9.5 0.0 2.4 2 0 0 2 2 2 0 OstA-like protein TFR_dimer PF04253.15 EON96329.1 - 8.5e-33 113.0 1.1 3.9e-32 110.9 0.0 2.7 3 0 0 3 3 3 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EON96329.1 - 5.9e-22 78.3 0.0 1.4e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EON96329.1 - 3.7e-13 49.3 0.1 7.1e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EON96329.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Nicastrin PF05450.15 EON96329.1 - 0.19 11.2 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 Nicastrin Glucos_trans_II PF14264.6 EON96330.1 - 0.04 13.3 0.3 0.062 12.6 0.3 1.3 1 0 0 1 1 1 0 Glucosyl transferase GtrII DUF2975 PF11188.8 EON96330.1 - 0.44 10.4 2.3 10 6.0 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2975) PAT1 PF09770.9 EON96331.1 - 0 1331.9 0.9 0 1331.7 0.9 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 GDH_N PF12466.8 EON96331.1 - 0.04 14.1 0.9 0.13 12.5 0.9 1.8 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal Egh16-like PF11327.8 EON96332.1 - 1.5e-70 237.3 9.6 1.9e-70 237.1 9.6 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor Tail_VII PF17091.5 EON96332.1 - 0.27 11.1 1.9 0.65 9.9 1.9 1.6 1 0 0 1 1 1 0 Inovirus G7P protein MFS_1 PF07690.16 EON96333.1 - 1e-24 87.2 50.2 1.1e-15 57.4 24.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HAD PF12710.7 EON96334.1 - 1e-22 81.5 0.0 1.4e-22 81.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EON96334.1 - 0.019 14.4 0.1 0.18 11.2 0.1 2.1 1 1 0 1 1 1 0 Putative Phosphatase UMPH-1 PF05822.12 EON96334.1 - 0.023 14.2 0.0 0.07 12.6 0.0 1.8 1 1 1 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Sec62 PF03839.16 EON96335.1 - 6.4e-71 238.3 1.5 6.4e-71 238.3 1.5 1.7 2 0 0 2 2 2 1 Translocation protein Sec62 TFIIA PF03153.13 EON96335.1 - 2.8 7.8 10.5 2.9 7.8 10.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Adaptin_N PF01602.20 EON96336.1 - 1.1e-101 341.0 0.0 1.3e-101 340.8 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EON96336.1 - 6e-15 55.7 0.2 1.7e-13 50.9 0.0 3.0 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EON96336.1 - 8.7e-14 51.7 2.1 1.3e-05 25.5 0.0 5.2 3 2 3 6 6 6 6 HEAT repeats HEAT PF02985.22 EON96336.1 - 1.7e-09 37.1 1.4 0.03 14.6 0.0 6.4 7 0 0 7 7 6 2 HEAT repeat HEAT_EZ PF13513.6 EON96336.1 - 8.7e-06 26.1 4.5 0.045 14.3 0.0 5.3 5 1 1 6 6 6 1 HEAT-like repeat Cohesin_HEAT PF12765.7 EON96336.1 - 0.00053 20.2 1.7 0.021 15.1 0.0 3.2 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion VHS PF00790.19 EON96336.1 - 0.047 13.5 0.3 19 5.1 0.0 3.1 3 0 0 3 3 3 0 VHS domain CLASP_N PF12348.8 EON96336.1 - 0.12 11.9 0.1 8.1 5.9 0.0 3.2 3 0 0 3 3 3 0 CLASP N terminal EH_Signature PF15611.6 EON96336.1 - 0.15 11.5 0.1 0.76 9.1 0.0 1.9 2 0 0 2 2 2 0 EH_Signature domain Cnd3 PF12719.7 EON96336.1 - 0.19 10.9 0.5 1.8 7.7 0.1 2.7 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain RNA_pol_3_Rpc31 PF11705.8 EON96336.1 - 4.3 7.5 20.1 6.5 6.9 20.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 EON96336.1 - 5.5 6.3 21.7 7.9 5.8 21.7 1.1 1 0 0 1 1 1 0 SDA1 TFIIB PF00382.19 EON96338.1 - 1.6e-25 88.9 0.7 1.1e-14 54.2 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EON96338.1 - 1e-21 77.2 11.5 1e-21 77.1 5.4 2.6 2 0 0 2 2 2 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 EON96338.1 - 0.00061 19.5 0.3 0.15 11.8 0.1 2.4 1 1 1 2 2 2 2 Cyclin, N-terminal domain Ribosom_S12_S23 PF00164.25 EON96339.1 - 4.4e-29 100.4 0.5 5.1e-29 100.2 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 LDcluster4 PF18306.1 EON96339.1 - 0.03 13.9 0.2 0.33 10.5 0.1 2.0 1 1 1 2 2 2 0 SLOG cluster4 family Ribosomal_S12 PF17487.2 EON96339.1 - 0.24 12.2 0.0 0.65 10.8 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein S12 Fungal_trans_2 PF11951.8 EON96340.1 - 1.9e-06 27.0 0.2 3.2e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cu-oxidase_2 PF07731.14 EON96341.1 - 2.1e-40 137.6 0.1 6.4e-40 136.1 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EON96341.1 - 3.4e-34 118.3 0.2 7.5e-34 117.1 0.0 1.6 2 0 0 2 2 2 1 Multicopper oxidase AA_permease_2 PF13520.6 EON96342.1 - 5.9e-11 41.8 10.6 7.2e-11 41.6 10.6 1.1 1 0 0 1 1 1 1 Amino acid permease Sensor PF13796.6 EON96342.1 - 3.4 7.7 11.8 6.4 6.8 4.7 2.0 2 0 0 2 2 2 0 Putative sensor DUF1129 PF06570.11 EON96342.1 - 6 6.3 8.8 6.8 6.1 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) KilA-N PF04383.13 EON96343.1 - 0.048 13.5 0.0 0.53 10.1 0.0 2.2 1 1 1 2 2 2 0 KilA-N domain DUF917 PF06032.12 EON96344.1 - 1.4e-110 369.4 2.8 3e-109 365.1 0.7 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 EON96344.1 - 0.0032 16.8 0.6 0.087 12.1 0.0 3.0 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase EBP PF05241.12 EON96345.1 - 8.5e-46 155.6 4.2 9.3e-46 155.5 4.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF924 PF06041.11 EON96346.1 - 9.4e-21 74.7 0.0 1.4e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) DUF596 PF04591.12 EON96346.1 - 0.014 15.5 0.1 0.04 14.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF596 Lipase_GDSL PF00657.22 EON96347.1 - 5.2e-10 39.6 0.0 7.7e-10 39.1 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EON96347.1 - 4.2e-06 27.3 3.5 1.4e-05 25.6 3.5 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lon_C PF05362.13 EON96348.1 - 3.3e-65 219.5 0.0 5.9e-65 218.7 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EON96348.1 - 2.9e-33 115.5 0.7 6.6e-33 114.4 0.2 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EON96348.1 - 5.4e-22 78.6 0.0 1.9e-21 76.9 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 EON96348.1 - 5.4e-08 32.7 0.1 1.8e-07 31.1 0.0 1.9 2 0 0 2 2 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 EON96348.1 - 5.4e-07 29.7 0.0 1.3e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EON96348.1 - 7.5e-07 29.4 0.0 4.2e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EON96348.1 - 4.8e-05 23.6 0.0 0.00073 19.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EON96348.1 - 4.9e-05 23.1 0.2 0.00066 19.5 0.0 2.9 5 0 0 5 5 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 EON96348.1 - 6.3e-05 22.1 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 EON96348.1 - 0.00025 21.5 1.0 0.0019 18.6 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EON96348.1 - 0.0069 16.9 0.2 0.07 13.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 EON96348.1 - 0.0085 16.1 0.0 0.038 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EON96348.1 - 0.022 14.5 0.0 0.098 12.4 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EON96348.1 - 0.037 14.4 0.0 0.16 12.4 0.0 2.2 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EON96348.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EON96348.1 - 0.048 13.6 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 EON96348.1 - 0.079 12.5 0.7 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EON96348.1 - 0.089 12.7 0.2 1.6 8.6 0.0 2.5 1 1 1 2 2 2 0 NTPase DNTTIP1_dimer PF18192.1 EON96348.1 - 0.089 13.1 0.8 5.1 7.5 0.2 3.2 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain ABC_tran PF00005.27 EON96348.1 - 1.1 9.7 4.5 0.87 10.1 0.0 2.8 3 0 0 3 3 3 0 ABC transporter PI31_Prot_N PF11566.8 EON96349.1 - 9.2e-32 110.1 0.1 1.2e-31 109.8 0.1 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EON96349.1 - 1.3e-18 68.0 18.4 1.3e-18 68.0 18.4 3.4 3 1 1 4 4 4 1 PI31 proteasome regulator PLDc_2 PF13091.6 EON96350.1 - 2e-16 60.1 0.0 4.7e-06 26.5 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 EON96350.1 - 5.2e-13 48.6 2.2 4.6e-06 26.6 0.1 2.8 3 0 0 3 3 3 2 Phospholipase D Active site motif Glyco_hydro_76 PF03663.14 EON96352.1 - 4.3e-130 434.5 10.6 4.9e-130 434.3 10.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 HAD_2 PF13419.6 EON96353.1 - 1.4e-08 35.1 0.0 1.7e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EON96353.1 - 3.9e-08 33.8 0.0 4.4e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribonuclease_T2 PF00445.18 EON96354.1 - 4.5e-26 92.2 0.0 5.2e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family DUF4240 PF14024.6 EON96354.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) FA_hydroxylase PF04116.13 EON96355.1 - 3.7e-09 37.0 0.9 3.7e-09 37.0 0.9 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Mpv17_PMP22 PF04117.12 EON96356.1 - 1.7e-21 76.2 0.2 1.7e-21 76.2 0.2 2.5 3 0 0 3 3 3 1 Mpv17 / PMP22 family Pkinase PF00069.25 EON96357.1 - 2.7e-14 53.2 0.7 1.4e-13 50.9 0.2 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON96357.1 - 8.8e-14 51.4 0.0 2e-12 47.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PLAC8 PF04749.17 EON96358.1 - 5.2e-22 78.7 9.0 6.5e-22 78.4 9.0 1.1 1 0 0 1 1 1 1 PLAC8 family DUF5525 PF17663.1 EON96358.1 - 0.8 7.7 8.1 0.94 7.5 8.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) DSS1_SEM1 PF05160.13 EON96359.1 - 4.6e-24 84.2 17.3 6.6e-24 83.7 17.3 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Cwf_Cwc_15 PF04889.12 EON96359.1 - 0.32 10.7 13.7 0.34 10.6 13.7 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nuf2 PF03800.14 EON96360.1 - 4.5e-40 137.0 0.3 1.5e-39 135.3 0.0 2.1 2 0 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 EON96360.1 - 5.1e-36 123.3 22.3 5.1e-36 123.3 22.3 4.2 4 1 0 4 4 4 1 Designed helical repeat protein 10 domain DUF3584 PF12128.8 EON96360.1 - 0.0026 15.4 38.3 0.0042 14.7 38.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Bacillus_HBL PF05791.11 EON96360.1 - 1.7 8.4 20.3 0.33 10.8 5.7 3.4 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Atg14 PF10186.9 EON96360.1 - 3 6.9 45.4 3.6 6.6 23.8 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Leu_zip PF15294.6 EON96360.1 - 9.1 5.7 45.1 0.58 9.6 23.0 2.3 1 1 0 2 2 2 0 Leucine zipper eIF-1a PF01176.19 EON96361.1 - 7.2e-22 77.0 0.1 1e-21 76.5 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Cytochrom_C PF00034.21 EON96362.1 - 8.9 7.5 11.2 0.27 12.4 1.9 3.2 3 1 0 3 3 3 0 Cytochrome c PGK PF00162.19 EON96363.1 - 1.9e-151 504.3 1.4 2.1e-151 504.2 1.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 EON96363.1 - 6.3e-05 22.9 0.3 0.012 15.6 0.0 3.4 3 2 0 3 3 3 1 PA domain DUF3530 PF12048.8 EON96363.1 - 0.0042 16.5 0.0 0.0067 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Peripla_BP_4 PF13407.6 EON96363.1 - 0.0045 16.6 1.9 0.01 15.4 1.9 1.5 1 0 0 1 1 1 1 Periplasmic binding protein domain Inositol_P PF00459.25 EON96364.1 - 5.7e-34 117.9 0.0 2.5e-33 115.8 0.0 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family Bep_C_terminal PF17841.1 EON96364.1 - 0.081 13.2 0.2 0.2 11.9 0.2 1.7 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) Metallophos PF00149.28 EON96365.1 - 9.1e-36 124.3 0.6 1.2e-35 123.9 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EON96365.1 - 0.037 14.5 0.2 0.094 13.2 0.2 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EON96365.1 - 0.062 13.5 0.0 0.099 12.8 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain BTB PF00651.31 EON96366.1 - 1.6e-07 31.6 0.0 4.3e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 EON96366.1 - 0.21 11.8 0.0 2 8.7 0.0 2.3 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Glyco_transf_15 PF01793.16 EON96367.1 - 6e-134 446.4 7.2 7.4e-134 446.1 7.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CDI PF02234.19 EON96367.1 - 0.44 10.8 3.5 0.29 11.3 0.6 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor Vps35 PF03635.17 EON96368.1 - 2.4e-292 971.9 0.0 1.8e-176 588.8 0.0 2.0 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 35 Cupin_1 PF00190.22 EON96369.1 - 1.4e-38 131.8 0.0 4.4e-19 68.6 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EON96369.1 - 3.4e-24 84.4 2.4 8.6e-13 47.8 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EON96369.1 - 1.7e-06 27.6 0.1 0.032 13.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EON96369.1 - 0.004 17.1 0.7 1.2 9.0 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Thioredoxin PF00085.20 EON96370.1 - 4.4e-42 142.2 0.0 5.4e-24 84.1 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EON96370.1 - 2.7e-10 40.5 0.0 2.8e-05 24.1 0.0 4.2 3 1 2 5 5 5 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EON96370.1 - 7.1e-07 29.7 1.6 0.24 11.8 0.1 4.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EON96370.1 - 9e-06 25.9 0.1 0.066 13.6 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 EON96370.1 - 2.1e-05 24.1 0.0 0.2 10.9 0.0 3.0 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EON96370.1 - 0.00046 20.3 0.6 0.78 10.0 0.2 3.8 3 1 0 3 3 3 2 Thioredoxin-like TraF PF13728.6 EON96370.1 - 0.0035 17.2 0.1 0.058 13.2 0.0 2.5 2 0 0 2 2 2 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 EON96370.1 - 0.013 15.4 3.3 0.6 10.0 0.1 3.5 3 1 1 4 4 4 0 AhpC/TSA family 7TM_GPCR_Srh PF10318.9 EON96370.1 - 0.055 12.5 0.0 0.093 11.7 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh TrbC_Ftype PF09673.10 EON96370.1 - 0.29 11.2 0.9 1.5 8.9 0.0 2.5 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin assembly protein HsbA PF12296.8 EON96372.1 - 1.2e-28 100.0 8.9 1.2e-28 100.0 8.9 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Peptidase_S24 PF00717.23 EON96373.1 - 4e-07 29.9 0.0 5.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Ldh_2 PF02615.14 EON96374.1 - 2.2e-126 421.6 0.8 2.4e-126 421.4 0.8 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase DUF3808 PF10300.9 EON96375.1 - 2e-125 419.2 0.0 2.6e-125 418.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.6 EON96375.1 - 0.0018 18.7 4.7 0.73 10.4 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF1039 PF06287.11 EON96375.1 - 0.0042 17.5 0.1 0.014 15.8 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1039) TPR_16 PF13432.6 EON96375.1 - 0.13 13.0 4.5 1.1 10.0 0.9 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EON96375.1 - 0.24 12.3 3.6 9.9 7.3 0.2 4.0 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EON96375.1 - 0.99 9.8 3.4 94 3.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Amidase PF01425.21 EON96376.1 - 4.1e-88 296.3 0.0 1.6e-87 294.4 0.0 1.8 1 1 0 1 1 1 1 Amidase IBN_N PF03810.19 EON96377.1 - 2.5e-12 46.5 0.0 2.6e-11 43.3 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EON96377.1 - 0.0047 17.0 0.0 0.52 10.4 0.0 3.9 4 0 0 4 4 4 1 Exportin 1-like protein Cse1 PF08506.10 EON96377.1 - 0.024 13.4 0.0 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Cse1 Ipi1_N PF12333.8 EON96377.1 - 0.088 13.4 0.0 0.39 11.3 0.0 2.1 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation DNA_topoisoIV PF00521.20 EON96378.1 - 1.5e-121 406.3 0.5 2.8e-121 405.4 0.1 1.7 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EON96378.1 - 3e-48 163.3 3.0 3e-48 163.3 3.0 2.4 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EON96378.1 - 4e-24 85.0 1.4 8.1e-24 84.0 1.4 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EON96378.1 - 1.4e-13 51.3 0.1 3.6e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EON96378.1 - 2.9e-06 27.4 0.0 1.8e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 Toprim domain HATPase_c_3 PF13589.6 EON96378.1 - 0.0017 18.2 0.4 0.005 16.7 0.4 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Spem1 PF15670.5 EON96378.1 - 1.3 8.5 8.8 0.16 11.5 1.2 2.6 2 0 0 2 2 2 0 Spermatid maturation protein 1 AT_hook PF02178.19 EON96378.1 - 6.6 7.0 14.4 14 5.9 4.7 3.3 2 0 0 2 2 2 0 AT hook motif RTA1 PF04479.13 EON96379.1 - 7.3e-70 234.8 4.5 9.6e-70 234.4 4.5 1.1 1 0 0 1 1 1 1 RTA1 like protein T4SS_CagC PF16943.5 EON96379.1 - 1.5 9.0 9.0 6 7.1 0.3 3.0 3 0 0 3 3 3 0 Cag pathogenicity island, type IV secretory system G_glu_transpept PF01019.21 EON96380.1 - 1.9e-78 264.5 0.1 2.1e-78 264.3 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase HORMA PF02301.18 EON96383.1 - 1.3e-07 31.5 0.0 4.6e-06 26.4 0.0 2.4 1 1 0 1 1 1 1 HORMA domain Sigma70_ner PF04546.13 EON96383.1 - 0.09 12.6 7.0 0.13 12.2 7.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region TFIIA PF03153.13 EON96383.1 - 0.19 11.7 4.9 0.27 11.2 4.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 EON96383.1 - 1.1 7.5 4.1 1.2 7.3 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Roughex PF06020.11 EON96383.1 - 1.6 7.7 4.7 2.3 7.2 4.7 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Nop14 PF04147.12 EON96383.1 - 1.7 6.7 10.0 2.1 6.4 10.0 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EON96383.1 - 2.6 6.0 19.3 3.4 5.6 19.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC27 PF09507.10 EON96383.1 - 4.3 6.6 8.4 0.23 10.8 3.2 1.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 TRAP_alpha PF03896.16 EON96383.1 - 7 5.8 5.8 9.6 5.3 5.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit KH_1 PF00013.29 EON96384.1 - 3.1e-25 87.8 3.5 1.7e-06 27.8 0.1 6.7 7 0 0 7 7 7 5 KH domain DUF4661 PF15576.6 EON96385.1 - 0.016 15.1 2.3 0.023 14.6 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DLH PF01738.18 EON96385.1 - 0.03 13.9 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EON96385.1 - 0.059 12.8 0.0 0.15 11.5 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family baeRF_family12 PF18856.1 EON96385.1 - 0.2 12.3 0.3 0.2 12.3 0.3 2.0 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 PBP PF01161.20 EON96386.1 - 1.4e-15 57.8 0.0 1.7e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Sugar_tr PF00083.24 EON96387.1 - 7.5e-104 348.1 21.5 8.5e-104 347.9 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON96387.1 - 9.6e-25 87.2 30.1 6.6e-19 68.0 8.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EON96387.1 - 0.00019 20.1 24.9 0.00033 19.3 7.1 2.8 2 2 1 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 EON96387.1 - 0.0016 16.8 10.1 0.0056 15.0 1.6 3.1 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Med21 PF11221.8 EON96388.1 - 1.5e-48 164.7 9.1 1.6e-48 164.6 9.1 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex GAS PF13851.6 EON96388.1 - 0.00013 21.4 5.9 0.12 11.7 0.1 2.1 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding DUF4455 PF14643.6 EON96388.1 - 0.0093 14.7 1.3 0.0093 14.7 1.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4455) Med9 PF07544.13 EON96388.1 - 0.012 15.7 1.3 0.012 15.7 1.3 3.0 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 BST2 PF16716.5 EON96388.1 - 0.028 15.0 4.3 5.8 7.6 3.5 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 CtIP_N PF10482.9 EON96388.1 - 0.11 12.6 4.4 0.22 11.6 1.7 2.2 1 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain TMF_DNA_bd PF12329.8 EON96388.1 - 0.23 11.5 12.4 0.034 14.2 7.9 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 EON96388.1 - 0.4 10.9 4.0 0.62 10.2 2.0 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 EON96388.1 - 0.49 10.9 10.4 1 9.9 10.4 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region TRI12 PF06609.13 EON96390.1 - 4.2e-08 32.1 14.8 5.4e-08 31.7 14.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EON96390.1 - 0.0074 15.3 49.5 0.11 11.4 34.1 3.2 1 1 2 3 3 3 3 Major Facilitator Superfamily Pox_A14 PF05767.12 EON96390.1 - 0.027 14.6 2.2 0.027 14.6 2.2 2.4 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF3959 PF13105.6 EON96390.1 - 0.51 9.8 6.7 0.068 12.7 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3959) She9_MDM33 PF05546.11 EON96391.1 - 1.3e-79 266.6 5.3 1.8e-79 266.1 5.3 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family BCAS2 PF05700.11 EON96391.1 - 0.0033 17.2 2.0 0.0033 17.2 2.0 2.6 1 1 1 3 3 3 1 Breast carcinoma amplified sequence 2 (BCAS2) FliD_N PF02465.18 EON96391.1 - 0.005 17.5 1.1 0.23 12.1 1.6 2.2 2 0 0 2 2 2 1 Flagellar hook-associated protein 2 N-terminus Serine_rich PF08824.10 EON96391.1 - 0.0066 16.5 2.6 0.67 9.9 0.6 2.4 2 1 0 2 2 2 1 Serine rich protein interaction domain DUF4763 PF15960.5 EON96391.1 - 0.1 11.9 0.5 0.19 11.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Filament PF00038.21 EON96391.1 - 0.28 10.7 4.2 0.11 12.1 0.8 1.8 2 0 0 2 2 2 0 Intermediate filament protein HIP1_clath_bdg PF16515.5 EON96391.1 - 0.29 11.8 6.3 4.2 8.0 1.3 2.8 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CDPS PF16715.5 EON96391.1 - 0.33 10.6 3.5 0.37 10.4 1.0 2.1 2 0 0 2 2 2 0 Cyclodipeptide synthase TMF_TATA_bd PF12325.8 EON96391.1 - 0.37 11.0 3.8 1.6 9.0 1.5 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PRKG1_interact PF15898.5 EON96391.1 - 0.41 11.6 4.2 11 6.9 2.9 2.5 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Tropomyosin_1 PF12718.7 EON96391.1 - 1.7 8.8 6.7 0.1 12.8 1.0 1.9 2 1 0 2 2 2 0 Tropomyosin like ZapB PF06005.12 EON96391.1 - 2.1 8.9 6.8 0.95 10.0 0.4 3.0 3 0 0 3 3 3 0 Cell division protein ZapB Metal_resist PF13801.6 EON96391.1 - 2.5 8.3 19.9 1.6 8.9 0.9 3.3 3 1 1 4 4 4 0 Heavy-metal resistance YscO PF07321.12 EON96391.1 - 2.7 7.9 13.3 0.19 11.7 0.5 3.1 3 0 0 3 3 3 0 Type III secretion protein YscO DUF4407 PF14362.6 EON96391.1 - 2.9 7.2 13.4 10 5.4 13.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FliJ PF02050.16 EON96391.1 - 3.2 8.0 8.6 0.15 12.3 0.6 2.6 3 0 0 3 3 3 0 Flagellar FliJ protein CENP-H PF05837.12 EON96391.1 - 7 7.1 9.2 3.7 8.0 4.0 2.8 3 1 0 3 3 3 0 Centromere protein H (CENP-H) Sugar_tr PF00083.24 EON96392.1 - 3.7e-70 237.0 15.8 4.2e-70 236.9 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON96392.1 - 9.2e-20 70.9 12.8 1.3e-19 70.3 12.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Thioredoxin PF00085.20 EON96393.1 - 3.9e-27 94.3 0.0 4.9e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EON96393.1 - 4.9e-07 30.2 0.1 1.5e-06 28.6 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EON96393.1 - 1.3e-05 25.0 0.0 1.4e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EON96393.1 - 7.3e-05 23.0 0.0 0.075 13.4 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 EON96393.1 - 0.00029 20.3 0.0 0.00034 20.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Phosducin PF02114.16 EON96393.1 - 0.00053 19.0 0.0 0.00065 18.7 0.0 1.0 1 0 0 1 1 1 1 Phosducin Redoxin PF08534.10 EON96393.1 - 0.012 15.3 0.3 0.44 10.3 0.3 2.1 1 1 1 2 2 2 0 Redoxin Glutaredoxin PF00462.24 EON96393.1 - 0.018 15.3 0.1 0.042 14.1 0.1 1.7 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_7 PF13899.6 EON96393.1 - 0.052 13.7 0.1 0.077 13.2 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 EON96393.1 - 0.072 13.0 0.1 0.15 12.0 0.1 1.6 1 1 1 2 2 2 0 AhpC/TSA family PAP_central PF04928.17 EON96394.1 - 3.3e-20 72.1 0.0 5.3e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain MJ1316 PF04457.12 EON96394.1 - 1.6e-19 70.4 0.2 4e-19 69.1 0.2 1.7 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain NTP_transf_2 PF01909.23 EON96394.1 - 8.1e-05 22.8 0.0 0.00022 21.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain 2_5_RNA_ligase2 PF13563.6 EON96394.1 - 0.00015 21.7 0.0 0.00035 20.5 0.0 1.7 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Exo_endo_phos PF03372.23 EON96394.1 - 0.00022 20.8 0.0 0.00059 19.4 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RPN2_C PF18004.1 EON96394.1 - 0.013 15.5 1.2 0.023 14.6 1.2 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CCDC106 PF15794.5 EON96394.1 - 0.16 11.6 0.2 0.29 10.8 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 EON96394.1 - 2.2 6.4 3.9 3.3 5.9 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1349 PF07081.11 EON96395.1 - 6.4e-25 87.9 0.0 8.6e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Asp PF00026.23 EON96397.1 - 0.0024 17.3 0.0 0.0024 17.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF5326 PF17260.2 EON96398.1 - 0.0028 17.8 0.3 0.0053 16.9 0.3 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5326) AA_permease PF00324.21 EON96399.1 - 8.2e-125 417.1 42.7 9.6e-125 416.9 42.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON96399.1 - 2.4e-29 102.5 47.5 2.8e-29 102.2 47.5 1.0 1 0 0 1 1 1 1 Amino acid permease GCR PF02155.15 EON96399.1 - 0.063 12.3 0.3 0.096 11.7 0.3 1.1 1 0 0 1 1 1 0 Glucocorticoid receptor WW PF00397.26 EON96400.1 - 7.6e-13 48.3 0.4 1.7e-12 47.2 0.4 1.7 1 0 0 1 1 1 1 WW domain KinB_sensor PF16767.5 EON96400.1 - 0.39 11.2 3.3 0.33 11.4 1.6 1.6 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB DUF2076 PF09849.9 EON96400.1 - 1.8 8.5 24.3 0.0082 16.2 6.6 2.3 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) RNA_pol_Rpc4 PF05132.14 EON96400.1 - 10 6.6 10.6 3.2 8.2 1.1 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 PhoLip_ATPase_C PF16212.5 EON96401.1 - 2.8e-68 230.4 14.1 5.3e-68 229.5 14.1 1.4 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EON96401.1 - 3.6e-20 71.4 1.1 7.3e-20 70.4 0.0 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EON96401.1 - 4.5e-13 50.0 0.0 5.2e-08 33.4 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EON96401.1 - 5.5e-07 29.3 0.0 1.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 EON96401.1 - 0.0001 22.3 0.0 0.0013 18.8 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EON96401.1 - 0.016 14.9 0.0 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TMEM164 PF14808.6 EON96401.1 - 0.08 12.3 0.1 0.19 11.0 0.1 1.6 2 0 0 2 2 2 0 TMEM164 family MFS_1 PF07690.16 EON96402.1 - 1.9e-35 122.4 23.5 7.2e-29 100.8 2.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON96402.1 - 2.8e-12 46.2 7.2 2.1e-11 43.4 0.3 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EON96402.1 - 3.5 6.4 19.2 0.067 12.0 4.3 2.7 1 1 2 3 3 3 0 MFS_1 like family Pkinase PF00069.25 EON96403.1 - 5.5e-60 203.0 0.0 1.2e-59 201.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON96403.1 - 8.9e-36 123.5 0.0 1.5e-35 122.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 EON96403.1 - 1.7e-25 88.9 19.8 1.1e-13 51.0 6.0 2.7 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 EON96403.1 - 7.6e-21 73.8 28.3 1.4e-12 47.3 9.7 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 EON96403.1 - 3.3e-14 53.3 1.0 1.1e-13 51.6 1.0 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 EON96403.1 - 8.5e-05 22.8 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain Caskin-Pro-rich PF16907.5 EON96403.1 - 0.022 15.3 1.0 0.022 15.3 1.0 3.5 4 0 0 4 4 4 0 Proline rich region of Caskin proteins Kinase-like PF14531.6 EON96403.1 - 0.038 13.3 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EON96403.1 - 0.15 11.0 0.0 0.3 10.0 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain zf-RING_9 PF13901.6 EON96403.1 - 5.8 6.8 21.6 3.6 7.5 6.4 2.5 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Sin_N PF04801.13 EON96404.1 - 7e-09 35.4 0.0 1.5e-08 34.3 0.0 1.5 2 1 0 2 2 2 1 Sin-like protein conserved region TPR_1 PF00515.28 EON96405.1 - 7.4e-07 28.7 8.2 0.0032 17.2 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EON96405.1 - 2.4e-05 24.7 2.0 8.8e-05 22.9 2.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EON96405.1 - 2.9e-05 23.9 6.6 0.45 10.8 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EON96405.1 - 0.046 14.1 3.0 0.14 12.6 0.4 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EON96405.1 - 0.088 12.5 0.9 0.3 10.8 0.3 2.2 2 0 0 2 2 2 0 TPR repeat ANAPC3 PF12895.7 EON96405.1 - 0.2 11.9 2.5 0.61 10.4 2.5 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EON96405.1 - 0.28 12.1 1.8 2 9.4 0.7 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EON96405.1 - 0.46 10.8 2.2 22 5.6 0.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat ACBP PF00887.19 EON96406.1 - 3.7e-24 84.7 1.9 4.2e-24 84.6 1.9 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein SUR7 PF06687.12 EON96407.1 - 1.9e-25 89.7 10.1 2.4e-25 89.4 10.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 EON96407.1 - 0.0042 17.0 3.5 0.0042 17.0 3.5 1.7 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Trep_Strep PF09605.10 EON96407.1 - 0.01 15.9 1.5 0.01 15.9 1.5 2.1 2 0 0 2 2 2 1 Hypothetical bacterial integral membrane protein (Trep_Strep) ERGIC_N PF13850.6 EON96407.1 - 0.3 11.5 1.9 1.3 9.4 0.1 2.3 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF1218 PF06749.12 EON96407.1 - 2.1 8.9 9.9 0.16 12.6 1.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) TauD PF02668.16 EON96408.1 - 2.2e-30 106.4 0.2 3.9e-30 105.6 0.2 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2922 PF11148.8 EON96408.1 - 0.16 11.7 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) Tad PF13400.6 EON96409.1 - 0.11 12.8 4.3 0.18 12.1 4.3 1.3 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like FeoB_associated PF12669.7 EON96409.1 - 0.15 12.5 2.3 0.26 11.7 2.3 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein PMP1_2 PF08114.11 EON96409.1 - 9 6.1 7.7 0.68 9.7 2.6 1.8 2 0 0 2 2 2 0 ATPase proteolipid family TauD PF02668.16 EON96410.1 - 1.5e-15 57.7 0.1 2e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lipase_GDSL_2 PF13472.6 EON96412.1 - 7.5e-16 59.0 0.5 9.3e-16 58.7 0.5 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EON96412.1 - 1.6e-10 41.3 0.2 1.8e-10 41.1 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EON96412.1 - 4.7e-05 23.6 0.1 5.8e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SASA PF03629.18 EON96412.1 - 0.023 14.4 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate esterase, sialic acid-specific acetylesterase TFIIA PF03153.13 EON96413.1 - 0.44 10.5 31.7 0.64 10.0 31.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 EON96413.1 - 2.5 7.2 16.9 2.8 7.0 16.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PAT1 PF09770.9 EON96413.1 - 8.4 4.5 19.0 13 3.9 19.0 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ALG3 PF05208.13 EON96414.1 - 2.1e-140 468.2 13.6 2.8e-140 467.8 13.6 1.1 1 0 0 1 1 1 1 ALG3 protein DAO PF01266.24 EON96414.1 - 6.1e-29 101.7 0.0 8.1e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON96414.1 - 0.00048 19.3 0.0 0.00081 18.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EON96414.1 - 0.002 18.3 0.1 0.0058 16.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EON96414.1 - 0.0038 16.5 0.0 0.0057 15.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EON96414.1 - 0.0047 16.2 0.1 0.0092 15.2 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EON96414.1 - 0.026 15.1 0.0 0.058 14.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON96414.1 - 0.028 13.1 0.2 0.041 12.6 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein AAA_lid_4 PF17864.1 EON96414.1 - 0.037 13.8 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 RuvB AAA lid domain AlaDh_PNT_C PF01262.21 EON96414.1 - 0.043 13.1 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EON96414.1 - 0.11 11.6 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 EON96414.1 - 0.16 11.6 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 EON96414.1 - 0.26 10.5 0.0 0.62 9.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Transp_cyt_pur PF02133.15 EON96415.1 - 8.7e-55 186.2 20.1 1.1e-54 186.0 20.1 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Acetyltransf_1 PF00583.25 EON96416.1 - 3.1e-07 30.6 0.0 3.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EON96416.1 - 2.8e-06 27.2 0.0 4.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EON96416.1 - 2.6e-05 24.2 0.0 3.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EON96416.1 - 0.0044 17.4 0.0 0.006 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NAD_binding_2 PF03446.15 EON96417.1 - 2.2e-38 131.9 0.1 3.3e-38 131.4 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EON96417.1 - 6.3e-30 103.9 0.2 1.4e-29 102.8 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 EON96417.1 - 4.4e-06 25.8 0.0 6.5e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 EON96417.1 - 4.9e-06 27.0 0.0 1.3e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 EON96417.1 - 2.9e-05 24.9 0.0 8e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 EON96417.1 - 0.013 15.8 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EON96417.1 - 0.051 13.5 0.3 0.22 11.4 0.3 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RRF PF01765.19 EON96417.1 - 0.19 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosome recycling factor Peptidase_M20 PF01546.28 EON96418.1 - 2.3e-32 112.4 0.0 3.4e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EON96418.1 - 2.6e-12 46.6 0.0 9.8e-12 44.8 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EON96418.1 - 0.0014 18.4 0.0 0.0058 16.3 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M28 Reticulon PF02453.17 EON96419.1 - 2.6e-34 118.5 4.4 3.5e-34 118.0 4.4 1.2 1 0 0 1 1 1 1 Reticulon Rho_GDI PF02115.17 EON96420.1 - 6.8e-62 208.7 0.1 1.3e-61 207.8 0.1 1.5 1 1 0 1 1 1 1 RHO protein GDP dissociation inhibitor Transp_cyt_pur PF02133.15 EON96421.1 - 9.1e-23 80.7 35.1 2.2e-22 79.5 35.1 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RabGAP-TBC PF00566.18 EON96422.1 - 3.4e-50 170.7 0.0 9.9e-50 169.2 0.0 1.9 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CpXC PF14353.6 EON96422.1 - 0.078 13.0 0.0 0.32 11.1 0.0 2.0 1 0 0 1 1 1 0 CpXC protein DUF1664 PF07889.12 EON96422.1 - 0.17 11.9 4.8 0.069 13.2 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TerB PF05099.13 EON96423.1 - 0.045 13.7 0.7 0.068 13.1 0.7 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TerB Inositol_P PF00459.25 EON96424.1 - 2.6e-64 217.4 0.0 3e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DIOX_N PF14226.6 EON96425.1 - 1.6e-17 64.4 0.0 3.2e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EON96425.1 - 1.3e-16 60.9 0.0 2.5e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.15 EON96426.1 - 3.8e-89 299.5 35.6 5.2e-89 299.0 35.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Aminotran_1_2 PF00155.21 EON96427.1 - 1.6e-62 211.8 0.0 2e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Acyl-CoA_dh_1 PF00441.24 EON96428.1 - 9.8e-37 126.5 3.8 1.6e-36 125.8 3.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON96428.1 - 7.4e-29 100.7 0.1 1.8e-28 99.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON96428.1 - 2.3e-23 82.2 0.0 4.2e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON96428.1 - 8.8e-18 64.9 1.0 1.4e-17 64.3 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EON96428.1 - 6.9e-05 22.6 0.1 0.00019 21.2 0.1 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Nup160 PF11715.8 EON96429.1 - 0.058 12.0 0.0 0.071 11.7 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Transp_cyt_pur PF02133.15 EON96430.1 - 1.9e-60 204.9 19.3 2.3e-60 204.7 19.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 EON96431.1 - 1.4e-26 93.3 23.2 2.1e-26 92.7 23.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON96431.1 - 0.24 10.2 26.2 2 7.2 5.1 3.2 1 1 2 3 3 3 0 Sugar (and other) transporter Peptidase_S8 PF00082.22 EON96432.1 - 2.8e-31 108.9 9.9 6.7e-31 107.6 9.8 1.6 1 1 0 1 1 1 1 Subtilase family GMC_oxred_N PF00732.19 EON96433.1 - 1.3e-29 103.5 0.1 1.4e-25 90.3 0.1 2.8 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EON96433.1 - 7.8e-29 101.1 0.0 1.3e-28 100.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EON96433.1 - 7.6e-05 22.1 0.1 0.0021 17.4 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON96433.1 - 0.0013 19.0 0.1 0.0046 17.2 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EON96433.1 - 0.0057 15.8 1.9 0.023 13.8 0.7 2.3 2 1 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EON96433.1 - 0.028 13.5 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EON96433.1 - 0.029 13.6 0.1 2.6 7.2 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EON96433.1 - 0.071 12.3 0.5 0.11 11.7 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 EON96433.1 - 0.71 9.4 6.0 7.4 6.0 0.1 2.7 2 1 0 3 3 3 0 FAD dependent oxidoreductase Vps62 PF06101.11 EON96434.1 - 8.5e-08 30.9 2.2 0.0002 19.8 0.2 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 PC_rep PF01851.22 EON96435.1 - 2.1e-08 34.2 0.1 0.015 15.8 0.0 4.8 4 0 0 4 4 4 3 Proteasome/cyclosome repeat CsiD PF08943.10 EON96435.1 - 0.021 13.9 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 CsiD RGS PF00615.19 EON96436.1 - 2e-08 34.5 0.0 3.8e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain peroxidase PF00141.23 EON96437.1 - 9.8e-87 290.4 0.0 1e-47 162.7 0.0 2.2 2 0 0 2 2 2 2 Peroxidase GST_C_3 PF14497.6 EON96437.1 - 0.036 14.2 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 EON96438.1 - 3e-32 111.9 25.3 3e-32 111.9 25.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.9 EON96438.1 - 0.14 12.4 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_1 PF07690.16 EON96439.1 - 1.1e-22 80.5 31.1 4.6e-18 65.3 10.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily COX14 PF14880.6 EON96439.1 - 0.036 13.9 0.0 0.036 13.9 0.0 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF3754 PF12576.8 EON96439.1 - 0.041 13.8 1.9 6.1 6.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) OSTbeta PF15048.6 EON96439.1 - 0.28 11.3 0.9 0.69 10.1 0.0 1.9 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein COX2_TM PF02790.15 EON96439.1 - 2.6 8.2 6.2 8.7 6.6 0.1 3.0 4 0 0 4 4 4 0 Cytochrome C oxidase subunit II, transmembrane domain zf-HC2 PF13490.6 EON96440.1 - 0.091 13.0 3.8 0.27 11.5 0.4 2.3 2 0 0 2 2 2 0 Putative zinc-finger Amidohydro_1 PF01979.20 EON96441.1 - 1.7e-17 63.8 0.2 1.3e-13 51.0 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EON96441.1 - 8.4e-13 48.6 0.4 2.3e-07 30.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.16 EON96442.1 - 1.2e-31 109.9 44.0 1.7e-30 106.2 39.7 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Clathrin PF00637.20 EON96443.1 - 1.1e-21 77.2 0.5 1.2e-19 70.6 0.6 3.3 4 1 0 4 4 4 1 Region in Clathrin and VPS CENP-B_dimeris PF09026.10 EON96443.1 - 0.00074 19.9 2.6 0.00074 19.9 2.6 3.0 3 0 0 3 3 3 1 Centromere protein B dimerisation domain Vps39_1 PF10366.9 EON96443.1 - 0.00074 19.8 0.1 0.044 14.1 0.0 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.6 EON96443.1 - 0.11 12.5 1.5 0.25 11.3 1.5 1.6 1 1 0 1 1 1 0 zinc-RING finger domain C1_1 PF00130.22 EON96443.1 - 0.2 11.5 0.3 0.38 10.7 0.3 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) WD40_like PF17005.5 EON96443.1 - 0.21 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain Coatomer_WDAD PF04053.14 EON96443.1 - 0.24 10.4 0.2 19 4.1 0.0 2.5 3 0 0 3 3 3 0 Coatomer WD associated region zf-rbx1 PF12678.7 EON96443.1 - 0.26 11.6 0.8 0.77 10.1 0.8 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EON96443.1 - 0.56 10.0 1.7 1.2 8.9 1.7 1.6 1 0 0 1 1 1 0 RING-like zinc finger BUD22 PF09073.10 EON96443.1 - 2.4 7.4 16.2 0.024 14.0 1.3 3.0 3 0 0 3 3 3 0 BUD22 DNA_pol_phi PF04931.13 EON96443.1 - 4.6 5.2 15.7 8.5 4.3 15.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi Eapp_C PF10238.9 EON96443.1 - 8.5 6.4 7.8 0.4 10.7 0.7 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein IDO PF01231.18 EON96446.1 - 3.8e-115 385.1 0.0 4.3e-115 385.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Aminotran_5 PF00266.19 EON96447.1 - 3.9e-07 29.4 0.0 3.6e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EON96447.1 - 0.038 13.3 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AAA PF00004.29 EON96448.1 - 7.5e-45 152.6 0.0 2.5e-44 150.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EON96448.1 - 2.3e-16 59.3 0.3 9e-09 35.0 0.0 3.1 4 0 0 4 4 4 2 AAA+ lid domain RuvB_N PF05496.12 EON96448.1 - 0.0017 18.1 0.0 0.0045 16.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EON96448.1 - 0.003 18.0 5.9 0.044 14.2 0.1 3.1 2 2 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 EON96448.1 - 0.011 15.3 0.1 0.53 9.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EON96448.1 - 0.012 16.0 1.1 0.82 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 EON96448.1 - 0.017 15.2 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EON96448.1 - 0.022 14.9 0.0 0.066 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EON96448.1 - 0.058 13.7 0.1 2 8.7 0.2 2.7 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 EON96448.1 - 0.089 12.8 0.0 0.53 10.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EON96448.1 - 0.11 11.8 0.1 0.31 10.4 0.1 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RRS1 PF04939.12 EON96449.1 - 1.4e-57 194.1 2.9 1.6e-57 193.9 2.9 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) IBR PF01485.21 EON96450.1 - 0.017 15.3 11.3 0.056 13.7 11.3 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain RhoGAP PF00620.27 EON96451.1 - 5.3e-27 94.5 0.0 1e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Aminotran_1_2 PF00155.21 EON96452.1 - 2.3e-36 125.8 0.0 2.5e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Med2 PF11214.8 EON96452.1 - 0.19 11.9 0.0 1 9.6 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 2 Sugar_tr PF00083.24 EON96453.1 - 6e-85 285.8 13.5 6.8e-85 285.6 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON96453.1 - 1.6e-30 106.3 39.9 1.2e-28 100.0 18.9 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EON96453.1 - 3.3e-05 22.5 0.4 3.3e-05 22.5 0.4 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MutS_V PF00488.21 EON96454.1 - 9e-70 234.5 0.7 4.6e-69 232.2 0.1 2.3 2 1 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EON96454.1 - 4e-36 125.1 0.8 8.3e-36 124.0 0.8 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EON96454.1 - 9.1e-29 100.0 0.0 2.1e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EON96454.1 - 5.9e-11 42.8 0.0 1.7e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EON96454.1 - 2.8e-05 24.4 0.0 0.00012 22.3 0.0 2.2 2 0 0 2 2 2 1 MutS family domain IV DUF4911 PF16256.5 EON96454.1 - 0.029 14.3 0.0 0.07 13.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) Myelin-PO_C PF10570.9 EON96454.1 - 1 9.8 4.4 1.2 9.6 0.0 3.0 3 0 0 3 3 3 0 Myelin-PO cytoplasmic C-term p65 binding region MCM PF00493.23 EON96455.1 - 3.3e-104 346.9 0.4 5.6e-104 346.1 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EON96455.1 - 3.5e-32 110.9 0.2 7.2e-32 109.9 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EON96455.1 - 1.8e-20 73.1 1.0 4.2e-20 72.0 1.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EON96455.1 - 2.8e-16 60.0 1.6 2.8e-16 60.0 1.6 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EON96455.1 - 1.5e-07 31.0 0.0 1.5e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EON96455.1 - 1.6e-06 28.1 0.1 1.4e-05 25.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 EON96455.1 - 0.0032 17.3 3.1 0.0059 16.4 1.1 2.5 1 1 1 2 2 2 1 AAA lid domain AAA_3 PF07726.11 EON96455.1 - 0.015 15.1 0.0 0.05 13.5 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 EON96455.1 - 0.042 14.5 0.8 0.042 14.5 0.8 2.9 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI C-terminal Alg6_Alg8 PF03155.15 EON96457.1 - 1.6e-91 307.7 16.4 6.6e-82 276.0 13.6 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family MFS_1 PF07690.16 EON96458.1 - 4.9e-35 121.1 47.2 3.7e-27 95.2 21.1 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EON96458.1 - 2.4e-05 23.4 26.8 6.2e-05 22.0 5.4 3.2 1 1 1 2 2 2 2 Sugar (and other) transporter TMPIT PF07851.13 EON96458.1 - 1.1 8.4 2.6 2 7.6 2.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein Sugar_tr PF00083.24 EON96459.1 - 1.3e-48 166.0 25.1 2.9e-35 122.0 11.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EON96459.1 - 5.4e-17 61.7 24.8 2e-10 40.2 7.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4410 PF14366.6 EON96459.1 - 0.14 12.1 0.3 17 5.3 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4410) Prenyltrans PF00432.21 EON96460.1 - 2.7e-58 193.4 3.8 7.1e-12 44.8 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EON96460.1 - 0.0009 18.4 0.0 0.13 11.3 0.0 3.3 2 1 2 4 4 4 1 Squalene-hopene cyclase N-terminal domain DAP3 PF10236.9 EON96461.1 - 7.5e-95 317.7 0.0 9.7e-95 317.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 EON96461.1 - 0.033 14.6 0.0 0.084 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain RSRP PF17069.5 EON96461.1 - 0.077 12.6 0.6 0.12 11.9 0.6 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 FAA_hydrolase PF01557.18 EON96462.1 - 1.4e-59 201.5 0.0 2.1e-59 200.8 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 EON96462.1 - 0.018 15.5 0.1 0.031 14.7 0.1 1.4 1 0 0 1 1 1 0 Type II transport protein GspH GatB_N PF02934.15 EON96463.1 - 9.8e-96 320.3 0.0 1.5e-95 319.7 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EON96463.1 - 4.2e-10 39.7 0.0 1.4e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 GatB domain Lactamase_B PF00753.27 EON96465.1 - 5.9e-09 36.2 0.1 7.8e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Clp_N PF02861.20 EON96465.1 - 0.064 13.4 0.0 6.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component Abhydrolase_1 PF00561.20 EON96466.1 - 1.5e-18 67.4 0.0 1.7e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON96466.1 - 7.2e-09 36.6 0.0 8.8e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON96466.1 - 1.9e-08 33.9 0.0 3.1e-08 33.2 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EON96466.1 - 0.00032 20.8 0.0 0.00059 19.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 EON96466.1 - 0.014 15.0 0.0 0.039 13.6 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Thioesterase PF00975.20 EON96466.1 - 0.016 15.3 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Palm_thioest PF02089.15 EON96466.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PGAP1 PF07819.13 EON96466.1 - 0.17 11.6 0.0 6 6.5 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein MFS_1 PF07690.16 EON96469.1 - 7.8e-35 120.4 25.7 7.8e-35 120.4 25.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON96469.1 - 4.3e-05 22.6 22.2 0.015 14.2 24.1 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter DUF3377 PF11857.8 EON96469.1 - 0.77 9.7 5.8 0.94 9.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) CRPA PF05745.11 EON96469.1 - 4.4 7.3 7.4 0.33 11.0 1.2 2.2 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Aldedh PF00171.22 EON96470.1 - 7e-180 598.5 0.4 7.9e-180 598.3 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EON96470.1 - 0.00041 19.5 0.0 0.00073 18.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 EON96470.1 - 0.029 13.8 0.1 3 7.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF4785 PF16024.5 EON96470.1 - 0.097 11.4 0.1 0.53 9.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4785) Peptidase_S8 PF00082.22 EON96471.1 - 1.2e-11 44.4 0.1 2.7e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EON96471.1 - 6.9e-06 26.7 0.0 2.2e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Fn3-like domain Transp_cyt_pur PF02133.15 EON96472.1 - 5.3e-30 104.6 37.4 8.4e-30 103.9 37.4 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin p450 PF00067.22 EON96473.1 - 6.3e-39 134.0 0.5 1.9e-26 92.8 0.1 2.4 2 1 0 2 2 2 2 Cytochrome P450 Glyco_hydro_31 PF01055.26 EON96474.1 - 4e-90 303.1 0.2 5.1e-90 302.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EON96474.1 - 1.1e-12 48.0 0.0 5e-12 46.0 0.0 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like ADH_zinc_N PF00107.26 EON96475.1 - 1.9e-12 47.3 0.0 3.2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON96475.1 - 8.9e-11 41.6 4.4 1.8e-10 40.7 4.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 EON96475.1 - 5.9e-05 22.5 0.1 9.4e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EON96475.1 - 0.00063 19.1 0.2 0.00099 18.5 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 EON96475.1 - 0.04 14.1 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ank_4 PF13637.6 EON96479.1 - 9.7e-10 38.8 0.0 6e-07 29.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EON96479.1 - 5.4e-08 33.3 0.0 1.2e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Helo_like_N PF17111.5 EON96479.1 - 7.2e-05 22.3 1.7 0.00012 21.6 0.8 1.8 1 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Ank_5 PF13857.6 EON96479.1 - 8.5e-05 22.8 0.0 0.0043 17.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EON96479.1 - 8.9e-05 22.8 0.1 0.031 14.7 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat zf-AD PF07776.15 EON96479.1 - 0.0016 18.6 0.1 0.0039 17.4 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger associated domain (zf-AD) Ank_3 PF13606.6 EON96479.1 - 0.018 15.5 0.0 8.1 7.4 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat F-box PF00646.33 EON96480.1 - 2.8e-07 30.2 0.0 4.4e-06 26.4 0.0 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EON96480.1 - 6.5e-05 22.8 0.2 6.5e-05 22.8 0.2 3.1 3 0 0 3 3 3 1 F-box-like Sugar_tr PF00083.24 EON96481.1 - 7.1e-74 249.3 27.7 1.1e-73 248.7 27.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON96481.1 - 6.3e-21 74.7 23.2 2.4e-20 72.8 18.9 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily YwiC PF14256.6 EON96481.1 - 0.12 12.7 0.2 0.12 12.7 0.2 2.9 3 1 0 3 3 3 0 YwiC-like protein TRI12 PF06609.13 EON96481.1 - 2.4 6.5 13.0 0.01 14.3 2.3 2.2 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Acyl-CoA_dh_1 PF00441.24 EON96482.1 - 6.4e-30 104.3 2.4 6.4e-30 104.3 2.4 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON96482.1 - 3.4e-20 72.0 0.0 7.4e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EON96482.1 - 3e-16 60.1 0.2 6.5e-16 59.0 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EON96482.1 - 3.6e-14 53.2 4.2 1.4e-13 51.2 2.2 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain adh_short_C2 PF13561.6 EON96483.1 - 4.1e-64 216.3 0.6 4.8e-64 216.1 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON96483.1 - 1.2e-40 139.1 0.5 1.4e-40 138.8 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON96483.1 - 9.4e-15 55.0 0.1 1.4e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 EON96483.1 - 0.032 14.3 0.3 0.08 13.1 0.3 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus YjeF_N PF03853.15 EON96483.1 - 0.1 12.5 0.1 0.27 11.1 0.1 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus Hexapep PF00132.24 EON96484.1 - 3.6e-12 45.5 12.8 2.5e-09 36.5 4.8 3.1 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EON96484.1 - 3.8e-07 29.7 10.4 4.2e-05 23.2 4.7 2.6 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 EON96484.1 - 0.15 12.4 0.1 0.27 11.5 0.1 1.4 1 0 0 1 1 1 0 Maltose acetyltransferase Transp_cyt_pur PF02133.15 EON96485.1 - 1.5e-59 202.0 12.2 1.7e-59 201.7 12.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Abhydrolase_3 PF07859.13 EON96486.1 - 2.1e-46 158.5 0.0 2.9e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EON96486.1 - 2.1e-08 33.5 0.0 8.7e-08 31.5 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EON96486.1 - 1.2e-05 24.9 0.0 0.018 14.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EON96486.1 - 0.00017 22.3 0.6 0.00028 21.5 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EON96486.1 - 0.034 14.0 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.18 EON96486.1 - 0.038 13.6 0.0 1.8 8.1 0.0 2.5 2 1 0 2 2 2 0 Dienelactone hydrolase family AXE1 PF05448.12 EON96486.1 - 0.18 10.4 0.0 0.83 8.3 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF4605 PF15378.6 EON96487.1 - 0.11 12.3 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4605) Peptidase_S28 PF05577.12 EON96488.1 - 1.3e-44 152.7 0.7 2.9e-44 151.6 0.7 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 NMT1 PF09084.11 EON96489.1 - 2.7e-12 47.1 0.0 3.5e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_3 PF16868.5 EON96489.1 - 2e-06 27.4 0.1 5.9e-06 25.9 0.1 1.6 1 1 1 2 2 2 1 NMT1-like family SBP_bac_3 PF00497.20 EON96489.1 - 2.6e-05 23.8 0.0 3.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 EON96489.1 - 0.00082 19.0 0.0 0.00099 18.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein OpuAC PF04069.12 EON96489.1 - 0.0097 15.5 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system FMO-like PF00743.19 EON96491.1 - 5.8e-25 87.7 0.0 7.8e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EON96491.1 - 6e-12 45.4 0.0 9.6e-12 44.8 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON96491.1 - 2.2e-09 37.0 0.0 1.2e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EON96491.1 - 1.9e-08 33.9 0.0 2.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON96491.1 - 5.8e-05 23.2 0.0 0.00032 20.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EON96491.1 - 5.8e-05 23.1 0.0 0.0011 19.0 0.0 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 EON96491.1 - 0.0014 18.3 0.0 2.1 7.8 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EON96491.1 - 0.011 15.0 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 EON96491.1 - 0.074 12.3 0.1 2.2 7.4 0.1 2.2 2 1 0 2 2 2 0 FAD binding domain Glu_dehyd_C PF16912.5 EON96491.1 - 0.084 12.3 0.0 4.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 EON96491.1 - 0.14 12.2 0.1 2.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Laminin_II PF06009.12 EON96492.1 - 0.0059 16.6 15.2 0.035 14.1 10.2 2.4 1 1 1 2 2 2 1 Laminin Domain II Lebercilin PF15619.6 EON96492.1 - 0.0066 16.1 13.2 0.0066 16.1 13.2 2.3 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Apo-CIII PF05778.12 EON96492.1 - 0.08 12.6 0.5 0.39 10.4 0.2 2.3 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) AAA_13 PF13166.6 EON96492.1 - 0.32 9.6 15.7 0.49 9.0 15.7 1.3 1 0 0 1 1 1 0 AAA domain TMCO5 PF14992.6 EON96492.1 - 0.53 9.8 17.6 0.87 9.1 17.6 1.3 1 0 0 1 1 1 0 TMCO5 family Neur_chan_memb PF02932.16 EON96492.1 - 0.56 10.2 8.6 0.85 9.6 8.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FUSC PF04632.12 EON96492.1 - 0.96 7.9 6.9 1.4 7.3 6.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 EON96492.1 - 2.3 7.5 14.3 3.5 6.9 14.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cauli_AT PF03233.13 EON96492.1 - 2.7 7.9 12.7 2.1 8.3 6.5 2.5 2 1 0 2 2 2 0 Aphid transmission protein GvpL_GvpF PF06386.11 EON96492.1 - 4.1 7.3 16.2 8.1 6.3 16.2 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Fez1 PF06818.15 EON96492.1 - 4.2 7.8 25.5 8.4 6.8 25.5 1.6 1 1 0 1 1 1 0 Fez1 DUF1664 PF07889.12 EON96492.1 - 5.7 7.0 13.3 0.28 11.2 5.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 EON96492.1 - 6.9 5.7 18.4 3.2 6.8 15.4 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 EON96492.1 - 7.1 6.8 35.2 2.5 8.3 17.4 2.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 EON96492.1 - 8.5 6.9 34.4 1.9 9.0 10.1 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 EON96492.1 - 8.8 4.1 13.8 11 3.7 13.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CC2-LZ PF16516.5 EON96492.1 - 9.7 6.6 24.2 0.44 10.9 4.3 3.0 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator SUZ PF12752.7 EON96493.1 - 0.49 11.2 3.2 1 10.2 3.2 1.5 1 0 0 1 1 1 0 SUZ domain PCI PF01399.27 EON96494.1 - 1.9e-11 44.4 0.0 1.8e-10 41.3 0.0 2.4 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 EON96494.1 - 0.00034 20.4 0.2 0.00034 20.4 0.2 1.8 2 1 0 2 2 2 1 26S proteasome subunit RPN7 TPR_12 PF13424.6 EON96495.1 - 6e-18 64.9 10.7 1.7e-05 25.0 1.1 8.6 7 1 0 7 7 7 4 Tetratricopeptide repeat AAA_22 PF13401.6 EON96495.1 - 2.5e-06 27.8 0.1 1.6e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EON96495.1 - 5e-06 27.0 0.0 2e-05 25.0 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EON96495.1 - 4.6e-05 23.4 0.1 0.00036 20.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain TPR_10 PF13374.6 EON96495.1 - 0.0033 17.3 6.0 9 6.3 0.5 6.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 EON96495.1 - 0.004 17.8 0.7 8.3 7.5 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF5039 PF16442.5 EON96495.1 - 0.02 14.5 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5039) FtsA PF14450.6 EON96495.1 - 0.16 12.4 0.0 0.87 10.0 0.0 2.3 2 0 0 2 2 2 0 Cell division protein FtsA TPR_2 PF07719.17 EON96495.1 - 1.2 9.4 3.6 1.3e+02 3.0 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat eIF-3_zeta PF05091.12 EON96496.1 - 3.7e-210 699.3 0.0 4.5e-210 699.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 EON96496.1 - 0.013 15.2 0.1 0.036 13.8 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF569) Proteasome PF00227.26 EON96498.1 - 1.4e-26 93.2 0.1 2.3e-26 92.5 0.1 1.3 1 1 0 1 1 1 1 Proteasome subunit MurJ PF03023.14 EON96498.1 - 0.072 11.7 0.0 0.095 11.3 0.0 1.1 1 0 0 1 1 1 0 Lipid II flippase MurJ TRI12 PF06609.13 EON96499.1 - 1.6e-23 83.0 4.8 1.9e-23 82.7 4.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EON96499.1 - 0.00013 21.0 15.7 0.00013 21.0 15.7 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2628 PF10947.8 EON96499.1 - 6.7 7.1 8.6 19 5.7 4.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) adh_short PF00106.25 EON96500.1 - 2.5e-38 131.5 0.0 3.6e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON96500.1 - 2.7e-31 108.9 0.0 4.4e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON96500.1 - 5.1e-07 29.8 0.0 1.4e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON96500.1 - 9.2e-05 22.0 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 EON96500.1 - 0.0092 16.7 0.0 0.041 14.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain 3HCDH_N PF02737.18 EON96500.1 - 0.023 14.6 0.1 0.04 13.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LpxI_N PF17930.1 EON96500.1 - 0.038 13.9 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 LpxI N-terminal domain TrkA_N PF02254.18 EON96500.1 - 0.043 14.1 0.0 0.077 13.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain DFP PF04127.15 EON96500.1 - 0.051 13.4 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein HSCB_C PF07743.13 EON96501.1 - 1.2e-20 73.7 8.0 1.2e-20 73.7 8.0 1.7 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EON96501.1 - 0.0047 17.0 0.4 0.062 13.4 0.4 2.4 1 1 0 1 1 1 1 DnaJ domain Utp14 PF04615.13 EON96501.1 - 0.011 14.3 0.9 0.014 14.0 0.9 1.1 1 0 0 1 1 1 0 Utp14 protein FBPase PF00316.20 EON96501.1 - 0.03 13.8 0.1 0.043 13.3 0.1 1.2 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain NUDIX PF00293.28 EON96502.1 - 2.4e-14 53.5 0.8 2.1e-13 50.4 0.1 2.3 1 1 2 3 3 3 1 NUDIX domain Egh16-like PF11327.8 EON96503.1 - 5.3e-44 150.8 7.2 7e-44 150.4 7.2 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor HemeBinding_Shp PF11545.8 EON96503.1 - 0.00049 20.1 0.1 0.00087 19.3 0.1 1.4 1 0 0 1 1 1 1 Cell surface heme-binding protein Shp MFS_1 PF07690.16 EON96504.1 - 0.00018 20.5 0.2 0.00018 20.5 0.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Orbi_VP3 PF01700.16 EON96504.1 - 0.11 10.4 0.0 0.12 10.3 0.0 1.1 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein Sugar_tr PF00083.24 EON96505.1 - 2.6e-27 95.8 29.7 1.9e-15 56.7 12.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Helicase_C PF00271.31 EON96506.1 - 0.014 15.7 0.2 0.21 11.9 0.2 2.3 1 1 0 1 1 1 0 Helicase conserved C-terminal domain Apolipoprotein PF01442.18 EON96507.1 - 2.2e-05 24.4 18.2 0.002 18.0 10.4 3.5 1 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 EON96507.1 - 0.0039 17.4 4.4 18 5.7 0.1 4.8 4 1 1 5 5 5 1 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 EON96507.1 - 0.33 8.9 1.1 0.61 8.0 0.4 1.8 1 1 0 1 1 1 0 Prominin DUF883 PF05957.13 EON96507.1 - 0.77 10.4 18.7 25 5.6 1.5 5.7 3 1 3 6 6 6 0 Bacterial protein of unknown function (DUF883) Phasin PF05597.11 EON96507.1 - 0.78 9.7 17.1 1.5 8.9 0.8 4.6 3 1 3 6 6 6 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HisKA_3 PF07730.13 EON96507.1 - 3.3 8.3 5.9 31 5.2 0.1 4.5 4 1 1 5 5 5 0 Histidine kinase DUF3712 PF12505.8 EON96508.1 - 5.7e-30 104.1 6.0 2e-29 102.4 2.5 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) DUF805 PF05656.14 EON96508.1 - 0.019 15.3 0.1 0.036 14.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF1053 PF06327.14 EON96508.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) Chordopox_A35R PF05989.12 EON96508.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A35R protein Oxidoreduct_C PF16490.5 EON96508.1 - 0.09 12.5 0.2 1.3 8.7 0.0 2.0 2 0 0 2 2 2 0 Putative oxidoreductase C terminal domain AAA PF00004.29 EON96509.1 - 7.1e-43 146.2 0.0 1.2e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EON96509.1 - 5.1e-12 45.6 0.1 2.3e-10 40.3 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EON96509.1 - 1.3e-10 40.9 0.1 2.5e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EON96509.1 - 6.7e-08 33.1 0.0 6.7e-05 23.3 0.1 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 EON96509.1 - 1.9e-06 28.1 0.0 9.2e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EON96509.1 - 2.2e-06 27.7 0.1 3.8e-05 23.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EON96509.1 - 7.1e-06 25.9 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EON96509.1 - 0.00022 21.5 0.1 0.006 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 EON96509.1 - 0.00034 19.9 0.0 0.00087 18.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EON96509.1 - 0.00035 21.1 0.2 0.0025 18.3 0.0 2.4 3 1 0 3 3 2 1 AAA domain AAA_7 PF12775.7 EON96509.1 - 0.0012 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EON96509.1 - 0.0021 17.3 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EON96509.1 - 0.0041 17.3 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EON96509.1 - 0.0043 16.5 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EON96509.1 - 0.0044 17.0 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EON96509.1 - 0.0054 16.5 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EON96509.1 - 0.0059 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 EON96509.1 - 0.0071 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EON96509.1 - 0.0084 15.8 0.0 0.028 14.1 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain eIF-1a PF01176.19 EON96509.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 AAA_3 PF07726.11 EON96509.1 - 0.013 15.3 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EON96509.1 - 0.019 14.7 0.0 0.057 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EON96509.1 - 0.023 14.5 0.5 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EON96509.1 - 0.037 13.7 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EON96509.1 - 0.038 13.3 0.6 0.14 11.4 0.0 2.2 3 0 0 3 3 3 0 KaiC Prot_ATP_OB_N PF17758.1 EON96509.1 - 0.047 13.4 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain NACHT PF05729.12 EON96509.1 - 0.056 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 EON96509.1 - 0.063 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Occludin_ELL PF07303.13 EON96509.1 - 0.072 13.8 0.1 0.19 12.5 0.1 1.7 1 0 0 1 1 1 0 Occludin homology domain AAA_25 PF13481.6 EON96509.1 - 0.087 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EON96509.1 - 0.089 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EON96509.1 - 0.1 11.8 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Thymidylate_kin PF02223.17 EON96509.1 - 0.12 12.1 0.0 3.8 7.2 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase Parvo_NS1 PF01057.17 EON96509.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF4200 PF13863.6 EON96509.1 - 1 9.8 5.5 0.16 12.4 1.4 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) Sugar_tr PF00083.24 EON96510.1 - 4.3e-72 243.4 22.3 4.8e-72 243.2 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON96510.1 - 1.4e-08 34.0 24.5 1.4e-08 34.0 24.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Dyp_perox PF04261.12 EON96511.1 - 2.4e-87 293.0 0.0 2.8e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family p450 PF00067.22 EON96512.1 - 3.4e-68 230.5 0.0 4.3e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EON96513.1 - 9.5e-16 57.7 51.4 7.1e-08 31.8 19.1 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EON96513.1 - 1.7e-08 33.4 22.4 2.7e-08 32.7 22.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FUN14 PF04930.15 EON96513.1 - 1 9.8 4.8 4.5 7.7 4.8 2.1 1 0 0 1 1 1 0 FUN14 family SIS PF01380.22 EON96514.1 - 1.7e-60 202.6 0.1 6.1e-32 110.2 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EON96514.1 - 3.5e-17 62.8 0.0 7.4e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EON96514.1 - 3e-10 40.1 0.0 6.9e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EON96514.1 - 0.0043 16.0 0.0 0.0071 15.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Lipase_GDSL_2 PF13472.6 EON96515.1 - 5.4e-22 79.0 0.0 6.8e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EON96515.1 - 1e-08 35.4 0.0 1.8e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Abhydrolase_6 PF12697.7 EON96517.1 - 3.1e-15 57.4 0.1 4.2e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON96517.1 - 5.8e-10 39.2 0.1 2.8e-09 37.0 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON96517.1 - 3.7e-09 36.2 0.0 1.6e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EON96517.1 - 0.014 14.8 0.0 0.042 13.3 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family UPF0227 PF05728.12 EON96517.1 - 0.021 14.8 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) BAAT_C PF08840.11 EON96517.1 - 0.039 13.9 0.1 0.61 10.0 0.0 2.4 2 1 1 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.8 EON96517.1 - 0.099 12.2 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) FMN_dh PF01070.18 EON96518.1 - 1.8e-104 349.5 0.0 2.3e-104 349.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EON96518.1 - 1.8e-19 69.6 0.0 4e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EON96518.1 - 2.9e-06 26.7 0.1 4.3e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EON96518.1 - 1.6e-05 24.1 0.0 3.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EON96518.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 EON96518.1 - 0.031 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family NMO PF03060.15 EON96518.1 - 0.037 13.4 0.2 0.063 12.7 0.2 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Bac_luciferase PF00296.20 EON96519.1 - 1.2e-30 107.1 0.0 2.1e-27 96.4 0.0 2.2 1 1 1 2 2 2 2 Luciferase-like monooxygenase FAD_binding_4 PF01565.23 EON96520.1 - 2.5e-21 75.9 8.0 1.2e-20 73.7 3.8 2.5 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.12 EON96520.1 - 6.5e-13 48.6 0.7 1.9e-12 47.1 0.2 2.1 2 0 0 2 2 2 1 Berberine and berberine like S100PBPR PF15427.6 EON96521.1 - 0.096 11.9 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 S100P-binding protein DUF1993 PF09351.10 EON96522.1 - 4.5e-30 104.9 0.2 4.9e-30 104.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) MFS_1 PF07690.16 EON96523.1 - 1.9e-26 92.8 26.5 1.9e-26 92.8 26.5 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON96523.1 - 0.0011 17.9 36.4 0.036 12.9 13.5 3.5 2 2 1 3 3 3 2 Sugar (and other) transporter Phage_holin_7_1 PF16081.5 EON96523.1 - 4.4 7.5 6.6 6.2 7.0 0.4 2.5 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF2985 PF11204.8 EON96525.1 - 5.6e-21 74.5 4.8 5.6e-21 74.5 4.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Proton_antipo_C PF01010.19 EON96525.1 - 0.17 11.5 0.3 0.97 9.0 0.0 2.0 2 0 0 2 2 2 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus DHDPS PF00701.22 EON96526.1 - 2.2e-40 138.2 0.0 2.6e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Transp_cyt_pur PF02133.15 EON96527.1 - 1.5e-11 43.8 22.1 4.6e-08 32.3 11.3 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin SWIB PF02201.18 EON96528.1 - 8.5e-26 89.6 0.2 1.2e-24 86.0 0.2 2.6 1 1 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 EON96528.1 - 2.2e-15 56.3 0.9 4e-15 55.5 0.3 1.8 2 0 0 2 2 2 1 DEK C terminal domain DTHCT PF08070.11 EON96528.1 - 0.0058 17.4 2.7 0.0058 17.4 2.7 2.4 1 1 1 2 2 2 1 DTHCT (NUC029) region Evr1_Alr PF04777.13 EON96529.1 - 7.2e-26 90.6 0.0 1.1e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Proteasome PF00227.26 EON96530.1 - 1.5e-47 161.6 0.3 1.7e-47 161.4 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Flavodoxin_1 PF00258.25 EON96530.1 - 0.094 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin Ribonuc_2-5A PF06479.12 EON96531.1 - 4.7e-46 156.1 0.0 1.2e-45 154.8 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.25 EON96531.1 - 2.8e-44 151.5 0.0 6.7e-42 143.7 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON96531.1 - 7.2e-22 77.9 0.0 3.7e-20 72.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 EON96531.1 - 1.5e-06 27.9 0.0 0.001 18.9 0.0 3.0 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.6 EON96531.1 - 1.6e-05 24.6 0.1 0.00017 21.3 0.1 2.2 1 1 1 2 2 2 1 PQQ-like domain Pkinase_fungal PF17667.1 EON96531.1 - 0.00091 18.1 0.0 0.0022 16.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EON96531.1 - 0.0019 18.2 0.5 0.0057 16.6 0.5 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EON96531.1 - 0.0069 15.8 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EON96531.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Neur_chan_memb PF02932.16 EON96531.1 - 0.14 12.2 2.1 0.15 12.1 0.4 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region GMC_oxred_N PF00732.19 EON96532.1 - 6.7e-60 203.0 0.0 9.4e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EON96532.1 - 9.6e-29 100.8 0.0 1.7e-28 99.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EON96532.1 - 8.9e-06 25.0 0.6 9e-05 21.7 0.4 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EON96532.1 - 8.7e-05 22.7 1.2 0.00041 20.5 0.4 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EON96532.1 - 0.00046 19.4 1.4 0.0023 17.1 1.4 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EON96532.1 - 0.0027 17.4 1.4 0.017 14.7 1.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EON96532.1 - 0.0094 15.2 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EON96532.1 - 0.036 13.3 0.5 0.3 10.3 0.5 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EON96532.1 - 0.059 12.6 0.2 0.11 11.7 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase C2 PF00168.30 EON96533.1 - 1.6e-11 44.4 0.0 3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain OPT PF03169.15 EON96534.1 - 5e-14 51.9 2.2 6.7e-14 51.5 2.2 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MFS_1 PF07690.16 EON96535.1 - 8.9e-14 51.2 29.5 8.1e-10 38.1 20.8 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON96535.1 - 1.8 7.3 25.9 0.037 12.9 2.0 3.5 3 1 1 4 4 4 0 Sugar (and other) transporter AA_permease PF00324.21 EON96536.1 - 3.8e-135 451.2 34.9 4.3e-135 451.0 34.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON96536.1 - 5.8e-36 124.2 38.4 7.6e-36 123.8 38.4 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.25 EON96537.1 - 6.6e-28 97.5 0.0 8.2e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON96537.1 - 7.9e-17 61.6 0.0 8.6e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EON96537.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.3 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Sugar_tr PF00083.24 EON96538.1 - 1.3e-86 291.3 31.0 1.5e-86 291.1 31.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON96538.1 - 1.8e-30 106.1 59.7 1.3e-28 100.0 30.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3917 PF13055.6 EON96538.1 - 0.038 14.4 0.6 0.038 14.4 0.6 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3917) DUF1980 PF09323.10 EON96538.1 - 0.5 10.3 2.9 2.2 8.1 2.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) SepZ PF06066.11 EON96538.1 - 2 8.7 8.3 2.7 8.2 4.5 2.8 2 1 1 3 3 3 0 SepZ FA_desaturase PF00487.24 EON96541.1 - 1.4e-18 67.6 14.6 1.4e-18 67.6 14.6 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EON96541.1 - 5.2e-17 61.7 0.1 1.3e-16 60.5 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TAP42 PF04177.12 EON96542.1 - 2.8e-113 378.3 0.0 3.2e-113 378.1 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family HAT PF02184.16 EON96542.1 - 0.016 15.1 0.1 0.035 14.1 0.1 1.5 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat ELM2 PF01448.24 EON96542.1 - 0.017 15.8 0.0 0.11 13.2 0.0 2.3 2 0 0 2 2 2 0 ELM2 domain Fungal_trans PF04082.18 EON96543.1 - 1e-20 73.9 1.0 1.3e-20 73.6 0.4 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain T4_deiodinase PF00837.17 EON96543.1 - 0.11 11.8 0.2 0.33 10.2 0.1 1.9 1 1 1 2 2 2 0 Iodothyronine deiodinase GTP_EFTU PF00009.27 EON96544.1 - 7.4e-35 120.3 1.8 8.5e-35 120.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EON96544.1 - 9.9e-20 70.6 0.0 2.4e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 EON96544.1 - 2e-09 37.2 0.4 9.2e-09 35.1 0.4 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 EON96544.1 - 8.3e-08 32.5 0.1 8.3e-08 32.5 0.1 4.0 5 0 0 5 5 5 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EON96544.1 - 2.4e-07 30.8 0.1 1.1e-05 25.5 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 EON96544.1 - 0.00089 19.5 0.0 0.0032 17.7 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EON96544.1 - 0.0069 16.2 1.9 0.0078 16.0 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein TrkA_C PF02080.21 EON96544.1 - 0.039 13.8 0.8 11 5.9 0.0 3.3 3 0 0 3 3 3 0 TrkA-C domain EMP70 PF02990.16 EON96545.1 - 9.1e-206 684.5 0.2 1.2e-205 684.2 0.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 MecA_N PF05223.11 EON96545.1 - 0.061 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain GDI PF00996.18 EON96547.1 - 9.2e-190 630.7 0.0 1e-189 630.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor eIF-5a PF01287.20 EON96548.1 - 4.8e-29 100.3 1.9 6.6e-29 99.8 1.9 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Response_reg PF00072.24 EON96548.1 - 0.018 15.2 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 Response regulator receiver domain EFP_N PF08207.12 EON96548.1 - 0.018 15.1 0.8 0.04 13.9 0.0 2.0 3 0 0 3 3 3 0 Elongation factor P (EF-P) KOW-like domain NCA2 PF08637.10 EON96549.1 - 1.5e-109 365.6 0.0 2e-109 365.3 0.0 1.1 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TMEM171 PF15471.6 EON96549.1 - 0.12 11.4 0.1 0.27 10.2 0.3 1.4 2 0 0 2 2 2 0 Transmembrane protein family 171 Ras PF00071.22 EON96550.1 - 2.4e-64 215.8 0.0 2.9e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EON96550.1 - 8e-34 116.4 0.0 1.3e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EON96550.1 - 4.8e-13 48.9 0.0 6.1e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EON96550.1 - 1.1e-05 25.1 0.1 2.3e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EON96550.1 - 0.00036 20.0 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EON96550.1 - 0.0027 17.8 0.0 0.0068 16.5 0.0 1.6 1 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EON96550.1 - 0.0029 17.6 0.2 2.1 8.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EON96550.1 - 0.027 13.9 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MCM PF00493.23 EON96550.1 - 0.032 13.3 0.0 0.081 12.0 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain FeoB_N PF02421.18 EON96550.1 - 0.056 13.0 0.0 0.28 10.7 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.29 EON96550.1 - 0.092 13.2 0.0 9.1 6.7 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EON96550.1 - 0.095 12.4 0.3 0.33 10.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EON96550.1 - 0.12 12.6 0.1 0.45 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EON96550.1 - 0.19 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DASH_Dad4 PF08650.10 EON96551.1 - 1.4e-33 114.6 7.1 1.6e-33 114.5 7.1 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.10 EON96551.1 - 0.62 10.3 5.4 5.7 7.2 5.3 2.0 1 1 0 1 1 1 0 DASH complex subunit Dad1 Eaf7 PF07904.13 EON96552.1 - 1.8e-26 92.6 0.1 1.8e-26 92.6 0.1 2.7 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 DASH_Ask1 PF08655.10 EON96552.1 - 2.1e-21 75.5 0.2 3.8e-21 74.7 0.2 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 CLN3 PF02487.17 EON96552.1 - 0.39 9.7 1.3 0.62 9.0 1.3 1.2 1 0 0 1 1 1 0 CLN3 protein CDC45 PF02724.14 EON96552.1 - 0.87 7.8 13.7 1.4 7.1 13.7 1.4 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EON96552.1 - 2.6 6.0 17.2 4 5.4 17.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 EON96552.1 - 2.6 7.4 23.4 0.23 10.8 18.5 1.7 2 0 0 2 2 2 0 SDA1 DUF4746 PF15928.5 EON96552.1 - 5.4 6.4 17.1 7.3 5.9 15.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Merozoite_SPAM PF07133.11 EON96552.1 - 7.7 6.5 24.7 0.11 12.5 17.3 1.6 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) MIF4G PF02854.19 EON96553.1 - 2.5e-55 187.4 0.0 1.2e-25 90.4 0.0 3.6 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 EON96553.1 - 1.7e-27 96.8 6.0 1.7e-27 96.8 6.0 2.8 3 0 0 3 3 3 1 Up-frameshift suppressor 2 MMR_HSR1 PF01926.23 EON96554.1 - 3.7e-08 33.4 0.0 5.1e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Sec63 PF02889.16 EON96555.1 - 5e-137 455.2 0.0 1.5e-81 273.3 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EON96555.1 - 2.6e-37 128.3 0.6 3.2e-25 88.9 0.3 3.5 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 EON96555.1 - 2.1e-15 57.1 0.0 2.8e-08 33.9 0.1 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EON96555.1 - 6.9e-15 55.4 0.1 4.9e-06 26.9 0.0 4.0 3 1 0 3 3 3 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 EON96555.1 - 3.6e-05 23.6 1.7 0.027 14.2 0.2 2.9 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 EON96555.1 - 5.7e-05 23.5 1.0 0.0029 17.9 0.5 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EON96555.1 - 0.0062 16.8 1.1 0.5 10.6 0.7 3.4 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 EON96555.1 - 0.021 13.9 0.0 0.93 8.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 EON96555.1 - 0.05 13.3 0.0 18 5.0 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein ABC_tran_CTD PF16326.5 EON96556.1 - 0.00041 20.5 2.6 0.00041 20.5 2.6 6.1 4 2 2 6 6 6 2 ABC transporter C-terminal domain DUF4239 PF14023.6 EON96556.1 - 2.4 7.8 9.7 14 5.4 1.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4239) Pribosyltran PF00156.27 EON96557.1 - 1.7e-17 63.4 0.8 2.6e-17 62.8 0.8 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EON96557.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase TatD_DNase PF01026.21 EON96559.1 - 6.9e-30 104.3 0.0 1.1e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Bul1_C PF04426.12 EON96561.1 - 2.5e-05 23.8 0.0 6.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Bul1 C terminus Arrestin_C PF02752.22 EON96561.1 - 0.0012 19.4 0.8 0.14 12.6 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EON96561.1 - 0.0012 18.9 0.0 0.0042 17.1 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_N PF04425.12 EON96561.1 - 0.0025 16.7 0.1 0.023 13.5 0.0 2.5 2 1 0 2 2 2 1 Bul1 N terminus DUF3251 PF11622.8 EON96561.1 - 0.029 14.0 0.1 0.065 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) SNF2_N PF00176.23 EON96563.1 - 1.8e-54 184.8 0.1 2.6e-54 184.3 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EON96563.1 - 1.6e-14 54.2 0.0 3.3e-13 50.0 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EON96563.1 - 1.6e-05 24.7 2.4 3.3e-05 23.8 2.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.29 EON96563.1 - 4.4e-05 23.3 0.0 8.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EON96563.1 - 0.00026 21.0 0.0 0.0023 18.0 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EON96563.1 - 0.004 16.4 0.0 0.0076 15.5 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Prok-RING_4 PF14447.6 EON96563.1 - 0.19 11.6 4.7 2.1 8.2 4.7 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EON96563.1 - 0.58 10.1 4.8 2.6 8.0 4.9 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fer4_10 PF13237.6 EON96563.1 - 0.83 9.8 2.9 2.8 8.1 0.5 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain PI-PLC-X PF00388.19 EON96564.1 - 0.00026 20.6 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain AF-4 PF05110.13 EON96564.1 - 0.89 7.6 1.7 1.1 7.2 1.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Yip1 PF04893.17 EON96566.1 - 2.6e-12 46.8 9.8 3.7e-12 46.3 9.8 1.4 1 0 0 1 1 1 1 Yip1 domain DUF2070 PF09843.9 EON96566.1 - 1.3 7.2 6.2 1.6 6.9 6.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Herpes_BTRF1 PF04682.12 EON96567.1 - 0.19 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region PAXNEB PF05625.11 EON96567.1 - 0.56 9.3 3.6 4.2 6.4 0.1 2.4 1 1 1 2 2 2 0 PAXNEB protein Peptidase_C12 PF01088.21 EON96568.1 - 5.8e-55 186.3 0.0 6.9e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 cNMP_binding PF00027.29 EON96569.1 - 4.9e-29 100.2 0.0 2.4e-15 56.3 0.1 5.6 6 0 0 6 6 6 3 Cyclic nucleotide-binding domain Patatin PF01734.22 EON96569.1 - 4e-15 56.5 8.8 1.5e-14 54.7 6.2 2.9 2 1 0 2 2 2 1 Patatin-like phospholipase p450 PF00067.22 EON96570.1 - 3.4e-51 174.4 0.0 6.8e-51 173.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 RNA_pol_Rpb5_C PF01191.19 EON96571.1 - 1e-33 115.0 1.1 2.8e-33 113.6 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EON96571.1 - 2.6e-28 98.4 0.0 4.2e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EON96571.1 - 2.8e-05 24.1 0.0 8.2e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Restriction endonuclease Mrr_cat_2 PF13156.6 EON96571.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease SE PF08491.10 EON96573.1 - 5.5e-89 297.9 0.0 6.8e-89 297.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EON96573.1 - 0.08 12.2 0.0 0.23 10.6 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Citrate_bind PF16114.5 EON96573.1 - 0.096 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding Ribonuclease_3 PF00636.26 EON96574.1 - 2.1e-45 153.6 0.2 2e-21 76.6 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EON96574.1 - 1.6e-25 89.7 0.0 2.1e-10 40.8 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 EON96574.1 - 4.6e-24 84.4 0.9 3.2e-22 78.5 0.1 3.4 4 0 0 4 4 4 1 Dicer dimerisation domain Helicase_C PF00271.31 EON96574.1 - 2.7e-13 50.2 0.3 2.5e-12 47.1 0.3 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON96574.1 - 1.9e-12 47.6 1.3 5.6e-12 46.0 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EON96574.1 - 8.4e-09 35.4 0.0 1.9e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 EON96574.1 - 0.0018 18.9 0.0 0.77 10.5 0.0 3.1 2 0 0 2 2 2 1 Double-stranded RNA binding motif AAA_22 PF13401.6 EON96574.1 - 0.011 16.0 0.0 0.05 13.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain Phage_int_SAM_3 PF14659.6 EON96574.1 - 0.027 14.8 0.0 13 6.1 0.0 3.1 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Rhodanese PF00581.20 EON96575.1 - 2.5e-14 53.7 0.0 3e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain Yip1 PF04893.17 EON96576.1 - 3.2e-11 43.2 18.1 5.9e-11 42.4 18.1 1.5 1 1 0 1 1 1 1 Yip1 domain GCP_N_terminal PF17681.1 EON96577.1 - 1.2e-53 182.7 0.1 2.8e-53 181.5 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EON96577.1 - 2.9e-39 135.3 1.1 1.3e-22 80.7 0.8 2.4 1 1 1 2 2 2 2 Gamma tubulin complex component C-terminal AAA PF00004.29 EON96578.1 - 1.8e-54 183.7 0.0 9.4e-41 139.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EON96578.1 - 4.2e-12 45.7 0.0 6.2e-10 38.7 0.2 2.8 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 EON96578.1 - 1.5e-06 28.7 0.4 0.67 10.3 0.0 4.3 2 2 1 4 4 4 1 AAA ATPase domain RuvB_N PF05496.12 EON96578.1 - 2.9e-05 23.9 0.0 0.00014 21.6 0.0 2.1 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EON96578.1 - 3e-05 24.1 0.0 0.056 13.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 EON96578.1 - 3.7e-05 24.0 4.7 3.6 7.9 0.2 5.0 3 2 2 5 5 5 1 AAA domain AAA_5 PF07728.14 EON96578.1 - 0.00011 22.2 2.0 0.087 12.8 0.0 4.0 3 2 1 4 4 4 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EON96578.1 - 0.00013 22.3 0.0 0.069 13.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EON96578.1 - 0.00016 21.3 0.6 1.1 8.8 0.0 3.5 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.6 EON96578.1 - 0.00018 21.7 0.0 1.6 8.9 0.0 3.7 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 EON96578.1 - 0.00047 20.1 5.8 0.16 11.9 0.8 3.6 2 1 1 3 3 3 1 NACHT domain RNA_helicase PF00910.22 EON96578.1 - 0.00074 19.9 0.0 1.9 8.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Sigma54_activ_2 PF14532.6 EON96578.1 - 0.003 17.7 0.0 0.15 12.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EON96578.1 - 0.0032 16.9 0.3 0.35 10.2 0.1 2.9 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EON96578.1 - 0.004 17.3 0.0 0.032 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 EON96578.1 - 0.0045 16.9 0.0 0.06 13.3 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain TsaE PF02367.17 EON96578.1 - 0.01 15.8 0.1 7.5 6.6 0.0 3.2 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 EON96578.1 - 0.023 14.5 0.0 9.9 5.8 0.0 2.7 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 EON96578.1 - 0.043 13.7 0.0 4 7.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EON96578.1 - 0.044 13.5 0.5 1.1 8.9 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EON96578.1 - 0.08 13.5 0.0 26 5.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 EON96578.1 - 0.11 11.6 0.3 0.63 9.2 0.2 2.2 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 CDC48_N PF02359.18 EON96578.1 - 0.14 12.3 0.0 0.61 10.3 0.0 2.1 2 0 0 2 2 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_17 PF13207.6 EON96578.1 - 0.18 12.2 0.2 49 4.3 0.0 3.3 2 1 0 2 2 2 0 AAA domain Zip PF02535.22 EON96579.1 - 4.1e-49 167.6 11.9 8.1e-49 166.6 11.9 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter PNP_phzG_C PF10590.9 EON96580.1 - 3.4e-21 75.0 1.8 3.4e-21 75.0 1.8 2.4 2 1 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EON96580.1 - 2.5e-18 66.0 0.0 4.2e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 EON96580.1 - 0.0036 17.9 0.1 0.0077 16.8 0.1 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Asp_protease PF09668.10 EON96581.1 - 2.5e-58 195.3 0.1 3.5e-58 194.8 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EON96581.1 - 2.8e-23 82.3 0.1 6.3e-23 81.2 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EON96581.1 - 1.3e-11 44.9 0.2 3.8e-11 43.5 0.1 1.8 2 0 0 2 2 2 1 Aspartyl protease UBA PF00627.31 EON96581.1 - 1.4e-09 37.7 0.2 2.8e-09 36.7 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 EON96581.1 - 4.8e-09 35.9 0.1 1e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.11 EON96581.1 - 0.0001 22.1 0.0 0.00019 21.2 0.0 1.4 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 EON96581.1 - 0.00066 19.9 0.0 0.0019 18.5 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.6 EON96581.1 - 0.0056 16.5 0.2 0.012 15.5 0.2 1.6 1 0 0 1 1 1 1 UBA-like domain UN_NPL4 PF11543.8 EON96581.1 - 0.096 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Fungal_trans_2 PF11951.8 EON96582.1 - 0.0036 16.2 0.1 0.0049 15.7 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glycos_transf_2 PF00535.26 EON96583.1 - 5.1e-25 88.2 0.0 8.5e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON96583.1 - 6.9e-10 39.2 0.5 5e-08 33.1 0.1 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EON96583.1 - 7.9e-05 22.3 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EON96583.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Vps52 PF04129.12 EON96584.1 - 6.2e-67 226.5 0.0 6.9e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family PI3_PI4_kinase PF00454.27 EON96585.1 - 4e-44 151.3 0.0 6e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Synaptobrevin PF00957.21 EON96588.1 - 1.3e-31 108.3 0.3 1.6e-31 107.9 0.3 1.1 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EON96588.1 - 8.4e-28 96.2 0.0 1.2e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain DEAD PF00270.29 EON96589.1 - 1.2e-27 96.8 0.0 2.2e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 EON96589.1 - 2.4e-20 73.1 0.1 6.3e-20 71.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 EON96589.1 - 1.1e-11 45.0 0.0 7e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON96589.1 - 1.3e-07 31.8 0.0 2.5e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 EON96589.1 - 0.0042 17.4 0.0 0.0099 16.2 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like MRP-L47 PF06984.13 EON96590.1 - 1.5e-20 73.1 0.3 1.5e-20 73.1 0.3 1.6 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Herpes_UL3 PF03369.13 EON96590.1 - 0.13 12.8 0.2 0.27 11.8 0.2 1.5 1 0 0 1 1 1 0 Herpesvirus UL3 protein Pyridox_oxase_2 PF12766.7 EON96591.1 - 4.4e-20 72.1 0.0 6.7e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RabGAP-TBC PF00566.18 EON96592.1 - 7.3e-13 48.7 0.0 9.9e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ETC_C1_NDUFA5 PF04716.14 EON96593.1 - 1.8e-28 98.1 1.7 2.1e-26 91.5 0.0 2.4 2 0 0 2 2 2 2 ETC complex I subunit conserved region Ku_PK_bind PF08785.11 EON96593.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Ku C terminal domain like Proteasome PF00227.26 EON96594.1 - 2.8e-57 193.3 0.1 3.5e-57 193.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EON96594.1 - 1.6e-12 46.9 0.0 3.6e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature YL1_C PF08265.11 EON96595.1 - 7.1e-17 60.9 0.2 1.1e-16 60.2 0.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain ubiquitin PF00240.23 EON96596.1 - 3.8e-34 116.3 0.6 4.9e-34 115.9 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 EON96596.1 - 1.8e-31 107.8 10.1 2.7e-31 107.2 10.1 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 EON96596.1 - 2.2e-16 59.4 0.7 3e-16 59.0 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EON96596.1 - 2.1e-05 24.9 0.1 7.4e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EON96596.1 - 0.0036 17.6 0.0 0.0055 17.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EON96596.1 - 0.0038 17.1 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EON96596.1 - 0.0077 16.3 0.1 0.016 15.3 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EON96596.1 - 0.014 15.4 1.0 4.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 EON96596.1 - 0.029 14.9 0.1 0.035 14.7 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EON96596.1 - 0.082 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain HSP70 PF00012.20 EON96597.1 - 1e-163 545.8 11.4 1e-163 545.8 11.4 2.8 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EON96597.1 - 2.4e-10 39.8 0.0 6.2e-09 35.1 0.0 2.3 2 0 0 2 2 2 1 MreB/Mbl protein Trans_reg_C PF00486.28 EON96597.1 - 0.13 12.4 0.0 0.51 10.4 0.0 2.0 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Methyltr_RsmB-F PF01189.17 EON96598.1 - 1.6e-33 116.0 0.0 1.2e-25 90.3 0.0 3.1 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EON96598.1 - 0.17 12.0 0.0 0.63 10.1 0.0 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase Profilin PF00235.19 EON96599.1 - 2.4e-43 147.5 0.8 2.7e-43 147.3 0.8 1.0 1 0 0 1 1 1 1 Profilin RD3 PF14473.6 EON96600.1 - 0.002 18.0 0.8 0.0029 17.4 0.8 1.3 1 0 0 1 1 1 1 RD3 protein Zip PF02535.22 EON96600.1 - 0.12 11.6 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 EON96600.1 - 0.16 12.0 0.7 0.18 11.8 0.7 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EIF4E-T PF10477.9 EON96600.1 - 3.7 6.3 17.0 4.9 5.9 17.0 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Amidohydro_1 PF01979.20 EON96602.1 - 5e-40 137.9 0.1 7.8e-40 137.2 0.1 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EON96602.1 - 6.3e-07 29.2 3.6 9.7e-05 22.0 0.3 2.8 2 1 0 2 2 2 2 Amidohydrolase family YdiH PF15930.5 EON96602.1 - 0.0027 17.8 0.0 0.0069 16.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function Pyridoxal_deC PF00282.19 EON96603.1 - 2.6e-64 217.3 0.0 3.4e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF1382 PF07131.11 EON96603.1 - 0.033 14.2 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) Got1 PF04178.12 EON96604.1 - 6.7e-16 58.7 8.6 8.4e-16 58.4 8.6 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Synaptobrevin PF00957.21 EON96605.1 - 3.5e-14 52.3 0.5 5.4e-14 51.7 0.5 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EON96605.1 - 1.9e-10 40.7 0.0 3.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Herpes_UL36 PF03586.13 EON96605.1 - 0.13 11.5 0.0 3 7.1 0.0 2.3 2 1 0 2 2 2 0 Herpesvirus UL36 tegument protein G-patch PF01585.23 EON96606.1 - 5.3e-07 29.4 0.3 8.9e-07 28.7 0.3 1.4 1 0 0 1 1 1 1 G-patch domain Guanylin PF02058.15 EON96606.1 - 0.053 14.0 1.6 0.07 13.6 0.1 1.9 2 0 0 2 2 2 0 Guanylin precursor SMK-1 PF04802.15 EON96607.1 - 5.8e-85 284.0 1.7 5.8e-85 284.0 1.7 2.4 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 YqgF PF14639.6 EON96607.1 - 0.3 10.9 1.6 2.4 8.0 0.0 3.2 4 0 0 4 4 4 0 Holliday-junction resolvase-like of SPT6 Chitin_synth_2 PF03142.15 EON96608.1 - 3.3e-18 65.6 2.3 5.4e-18 64.9 2.3 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EON96608.1 - 2.7e-11 43.8 10.3 2.9e-10 40.4 9.5 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EON96608.1 - 0.0043 17.0 0.3 0.0076 16.2 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_hydro_17 PF00332.18 EON96609.1 - 1.8e-08 34.3 0.8 3.1e-08 33.6 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Ran_BP1 PF00638.18 EON96610.1 - 1.7e-12 47.7 5.3 2.9e-06 27.5 0.2 2.9 3 0 0 3 3 3 2 RanBP1 domain NOG1_N PF17835.1 EON96611.1 - 2.3e-49 167.5 0.0 2.3e-49 167.5 0.0 2.1 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOGCT PF08155.11 EON96611.1 - 9e-27 92.8 1.6 1.8e-26 91.8 1.6 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 EON96611.1 - 1.5e-25 88.7 0.4 3.4e-25 87.6 0.4 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EON96611.1 - 2.8e-15 56.4 0.0 6.5e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EON96611.1 - 6e-09 35.6 0.0 1.3e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EON96611.1 - 0.0013 18.8 0.7 0.96 9.5 0.0 3.2 3 0 0 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 EON96611.1 - 0.0014 18.6 2.0 0.33 10.8 0.1 3.9 4 1 0 4 4 4 1 RsgA GTPase Gtr1_RagA PF04670.12 EON96611.1 - 0.032 13.6 0.5 0.079 12.3 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EON96611.1 - 0.06 13.7 4.6 0.18 12.2 0.0 3.5 3 1 2 5 5 5 0 AAA ATPase domain AAA_18 PF13238.6 EON96611.1 - 0.089 13.3 0.0 2.2 8.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF1690 PF07956.11 EON96611.1 - 1.4 9.4 8.0 5.3 7.5 0.0 3.1 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) SUV3_C PF12513.8 EON96612.1 - 4.8e-18 64.8 1.8 1.2e-17 63.6 1.8 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 EON96612.1 - 1.2e-12 47.4 0.1 2.7e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 EON96612.1 - 7.1e-08 32.8 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mo-co_dimer PF03404.16 EON96613.1 - 7.2e-60 201.0 0.1 1.5e-59 199.9 0.1 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 EON96613.1 - 6.7e-58 195.1 0.0 1.2e-57 194.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 EON96613.1 - 1.1e-32 112.3 0.0 2e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EON96613.1 - 1.8e-26 92.9 0.0 6.7e-26 91.1 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 EON96613.1 - 3.1e-22 78.5 0.0 5.7e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EON96613.1 - 0.01 16.0 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Acetyltransf_10 PF13673.7 EON96614.1 - 3.7e-10 39.8 0.0 4.8e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON96614.1 - 9.8e-08 32.2 0.0 1.6e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON96614.1 - 7.5e-07 29.5 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EON96614.1 - 0.0078 16.3 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EON96614.1 - 0.059 13.5 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase YqeY PF09424.10 EON96615.1 - 1.3e-24 86.9 6.3 1.6e-24 86.6 6.3 1.1 1 0 0 1 1 1 1 Yqey-like protein Actin PF00022.19 EON96616.1 - 6.7e-53 179.8 0.0 1.4e-32 112.8 0.0 2.5 2 1 0 2 2 2 2 Actin adh_short PF00106.25 EON96617.1 - 1.5e-15 57.2 0.0 8.8e-12 44.9 0.0 2.9 3 1 1 4 4 4 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON96617.1 - 6.3e-06 25.9 0.0 9.6e-05 22.0 0.0 2.5 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON96617.1 - 2.4e-05 24.3 0.1 0.00011 22.2 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EON96617.1 - 0.00057 19.4 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NACHT_N PF17100.5 EON96617.1 - 2.7 7.8 9.5 4.9 6.9 9.5 1.4 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase Spc24 PF08286.11 EON96618.1 - 3.7e-39 133.2 4.1 4.3e-37 126.6 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 V_ATPase_I PF01496.19 EON96618.1 - 0.0036 15.3 0.9 0.0036 15.3 0.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TMCO5 PF14992.6 EON96618.1 - 0.01 15.4 4.0 0.013 15.1 4.0 1.1 1 0 0 1 1 1 0 TMCO5 family Nsp1_C PF05064.13 EON96618.1 - 0.014 15.2 6.2 0.72 9.7 1.3 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region Vps5 PF09325.10 EON96618.1 - 0.034 13.7 4.1 0.05 13.2 4.1 1.3 1 0 0 1 1 1 0 Vps5 C terminal like DUF2203 PF09969.9 EON96618.1 - 0.038 14.7 2.3 0.065 13.9 2.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) FlaC_arch PF05377.11 EON96618.1 - 0.04 14.3 1.0 0.31 11.5 0.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) BRE1 PF08647.11 EON96618.1 - 0.046 13.8 6.9 0.082 13.0 6.9 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase MAGSP PF03082.14 EON96618.1 - 0.065 12.8 2.6 0.096 12.3 2.6 1.2 1 0 0 1 1 1 0 Male accessory gland secretory protein Exonuc_VII_L PF02601.15 EON96618.1 - 0.07 12.7 3.4 0.086 12.4 3.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit AATF-Che1 PF13339.6 EON96618.1 - 0.11 13.1 4.0 0.17 12.6 4.0 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Scaffolding_pro PF11418.8 EON96618.1 - 0.31 11.6 3.1 7.4 7.2 1.2 2.6 1 1 2 3 3 3 0 Phi29 scaffolding protein DUF724 PF05266.14 EON96618.1 - 0.39 10.5 6.2 0.58 10.0 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Rop-like PF05082.13 EON96618.1 - 0.39 10.6 4.9 3.2 7.6 0.5 2.3 2 0 0 2 2 2 0 Rop-like Prefoldin_2 PF01920.20 EON96618.1 - 0.46 10.5 7.4 1.6 8.7 2.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF948 PF06103.11 EON96618.1 - 0.54 10.5 4.3 2.3 8.5 1.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1690 PF07956.11 EON96618.1 - 0.57 10.6 8.6 1.1 9.7 8.5 1.5 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF4337 PF14235.6 EON96618.1 - 0.8 9.8 5.7 1.2 9.3 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3138 PF11336.8 EON96618.1 - 1.4 7.5 3.8 1.6 7.2 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CcmH PF03918.14 EON96618.1 - 2.3 7.5 5.1 1.4 8.2 0.9 2.0 1 1 1 2 2 2 0 Cytochrome C biogenesis protein CLZ PF16526.5 EON96618.1 - 2.8 8.4 9.0 4.9 7.6 2.0 2.7 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels APG6_N PF17675.1 EON96618.1 - 2.9 8.4 13.1 7.2 7.2 12.8 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region RmuC PF02646.16 EON96618.1 - 3.1 6.9 9.3 1.2 8.2 4.2 2.1 1 1 1 2 2 2 0 RmuC family Uso1_p115_C PF04871.13 EON96618.1 - 5.2 7.5 12.8 10 6.5 0.5 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region XhlA PF10779.9 EON96618.1 - 5.3 7.3 6.2 3.8 7.8 1.4 2.2 2 0 0 2 2 2 0 Haemolysin XhlA SlyX PF04102.12 EON96618.1 - 5.9 7.6 8.2 18 6.1 0.3 2.6 1 1 0 2 2 2 0 SlyX DASH_Dam1 PF08653.10 EON96618.1 - 6.2 6.7 9.4 2 8.3 0.6 3.7 4 0 0 4 4 4 0 DASH complex subunit Dam1 DASH_Hsk3 PF08227.11 EON96618.1 - 8 6.9 11.8 8.1 6.9 1.2 2.5 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like FA_hydroxylase PF04116.13 EON96620.1 - 1.4e-26 93.4 16.5 1.4e-26 93.4 16.5 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Fis1_TPR_C PF14853.6 EON96621.1 - 1.6e-25 88.9 1.7 2.9e-25 88.1 1.7 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EON96621.1 - 6.2e-17 61.0 0.0 1.1e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EON96621.1 - 0.01 15.9 1.5 0.01 15.9 1.5 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.6 EON96622.1 - 5.2e-06 26.6 11.4 7.9e-06 26.1 1.1 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EON96622.1 - 0.00028 21.5 15.1 0.027 15.3 5.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 EON96622.1 - 0.00029 21.1 4.5 0.00051 20.3 4.5 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 EON96622.1 - 0.039 14.2 3.1 3.9 7.9 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EON96622.1 - 0.079 13.5 14.6 0.16 12.5 7.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type EIF_2_alpha PF07541.12 EON96623.1 - 5.5e-38 129.6 0.0 1.1e-37 128.7 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EON96623.1 - 4.6e-12 46.1 0.5 9.4e-12 45.1 0.5 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Ribonuclease_T2 PF00445.18 EON96624.1 - 2.9e-30 105.9 0.9 4.4e-30 105.3 0.9 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Na_Ca_ex PF01699.24 EON96626.1 - 4.1e-25 88.5 27.1 4.4e-13 49.5 8.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein 7tm_7 PF08395.12 EON96626.1 - 0.00071 18.9 1.5 0.00088 18.6 0.0 1.8 2 0 0 2 2 2 1 7tm Chemosensory receptor MIG-14_Wnt-bd PF06664.12 EON96626.1 - 0.005 16.1 7.5 0.04 13.2 7.5 2.2 1 1 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF1298 PF06974.13 EON96626.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) Otopetrin PF03189.13 EON96626.1 - 0.089 11.6 1.4 0.19 10.5 1.4 1.5 1 0 0 1 1 1 0 Otopetrin ArAE_2_N PF10337.9 EON96626.1 - 7.4 5.5 10.9 6.2 5.7 4.9 2.3 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal Methyltransf_8 PF05148.15 EON96627.1 - 2.5e-58 197.5 0.2 1e-55 189.0 0.0 3.3 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EON96627.1 - 1.4e-06 28.8 0.0 8e-06 26.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON96627.1 - 6.6e-05 23.5 0.1 0.0054 17.4 0.1 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON96627.1 - 0.023 14.5 0.0 3 7.6 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain tRNA-synt_1g PF09334.11 EON96627.1 - 0.036 12.8 0.0 0.065 12.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (M) Methyltransf_32 PF13679.6 EON96627.1 - 0.14 12.1 0.0 0.14 12.1 0.0 3.0 2 1 0 2 2 1 0 Methyltransferase domain MTS PF05175.14 EON96627.1 - 0.14 11.7 0.0 9.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain SR-25 PF10500.9 EON96627.1 - 0.21 11.2 31.5 0.55 9.8 31.5 1.8 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SOBP PF15279.6 EON96627.1 - 0.36 11.4 18.8 0.55 10.8 18.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Presenilin PF01080.17 EON96627.1 - 3.6 6.3 17.9 5.6 5.6 17.9 1.3 1 0 0 1 1 1 0 Presenilin SAGA-Tad1 PF12767.7 EON96627.1 - 7.9 6.1 16.8 14 5.4 16.8 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Peptidase_S30 PF01577.16 EON96627.1 - 8.1 6.0 20.9 15 5.1 20.9 1.5 1 0 0 1 1 1 0 Potyvirus P1 protease SpoIIIAH PF12685.7 EON96627.1 - 9.8 5.9 18.8 20 4.9 15.9 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein CPSase_L_D2 PF02786.17 EON96628.1 - 1e-112 374.8 0.2 1.5e-83 279.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 EON96628.1 - 7.9e-47 159.5 0.0 1.8e-46 158.3 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EON96628.1 - 1.2e-46 157.7 0.0 2.8e-46 156.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 EON96628.1 - 2.1e-42 144.6 0.0 4.5e-42 143.6 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 EON96628.1 - 1.9e-39 134.8 0.0 4.2e-39 133.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EON96628.1 - 7.9e-29 100.8 0.0 2.3e-28 99.3 0.0 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 EON96628.1 - 3.5e-22 78.4 0.0 1.7e-21 76.2 0.0 2.3 2 0 0 2 2 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 EON96628.1 - 7.6e-17 61.5 0.9 3.9e-08 33.1 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EON96628.1 - 1.4e-16 60.6 0.1 1.9e-08 34.1 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EON96628.1 - 5.7e-10 39.0 0.0 4.5e-05 23.2 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 EON96628.1 - 2.8e-06 27.2 0.2 0.00022 21.1 0.2 2.6 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EON96628.1 - 1.6e-05 24.8 0.0 0.067 13.0 0.0 4.2 4 0 0 4 4 4 1 DJ-1/PfpI family ATP-grasp_3 PF02655.14 EON96628.1 - 1.6e-05 25.0 0.3 0.094 12.8 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 EON96628.1 - 0.0018 18.1 0.1 1.1 8.9 0.0 2.9 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Transglut_core PF01841.19 EON96629.1 - 3.2e-12 46.9 0.2 6.8e-12 45.8 0.2 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily RRM_1 PF00076.22 EON96630.1 - 1.4e-32 111.3 0.0 2.2e-15 56.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 EON96630.1 - 0.0024 17.5 0.3 1.8 8.3 0.1 2.5 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_7 PF16367.5 EON96630.1 - 0.003 17.6 0.1 1.1 9.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 EON96630.1 - 0.0055 16.3 0.0 0.049 13.2 0.0 2.1 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EON96630.1 - 0.026 14.7 0.0 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter 2-Hacid_dh_C PF02826.19 EON96631.1 - 6.3e-52 175.5 0.0 1.1e-51 174.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EON96631.1 - 2e-16 59.9 0.0 2.8e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EON96631.1 - 0.0003 21.0 0.0 0.00082 19.6 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 EON96631.1 - 0.0085 15.4 0.1 0.39 10.0 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain SNRNP27 PF08648.12 EON96632.1 - 4.8e-28 97.0 1.7 9.9e-28 96.0 1.7 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins TFIIA PF03153.13 EON96632.1 - 0.63 10.0 5.3 0.79 9.7 5.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UQ_con PF00179.26 EON96633.1 - 4e-50 169.1 0.0 4.6e-50 168.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EON96633.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B PhoLip_ATPase_C PF16212.5 EON96634.1 - 5.9e-48 163.8 8.1 9e-48 163.2 8.1 1.2 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EON96634.1 - 1.4e-15 58.1 0.2 5e-09 36.7 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EON96634.1 - 7.1e-06 26.0 0.0 0.0005 20.1 0.0 2.8 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EON96634.1 - 0.00051 19.9 0.0 0.001 18.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_L28e PF01778.17 EON96635.1 - 5.8e-37 127.0 2.0 1.2e-36 126.0 2.0 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 EON96635.1 - 8.1e-30 103.4 16.8 8.1e-30 103.4 16.8 2.9 2 1 0 2 2 2 1 Mak16 protein C-terminal region TFIIA PF03153.13 EON96635.1 - 0.00044 20.4 8.6 0.00056 20.0 8.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 EON96635.1 - 0.0034 16.8 20.1 0.0046 16.4 20.1 1.2 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 EON96635.1 - 0.015 15.1 1.1 0.025 14.4 1.1 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain FCH PF00611.23 EON96635.1 - 0.57 10.5 6.2 1.8 8.9 0.6 2.5 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain SDA1 PF05285.12 EON96635.1 - 1.7 8.0 31.6 2.5 7.5 31.6 1.3 1 0 0 1 1 1 0 SDA1 MIF4G_like PF09088.11 EON96636.1 - 1.2e-89 299.2 1.0 1.7e-89 298.6 1.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EON96636.1 - 4.9e-73 245.9 0.0 7.2e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 MIF4G like PsaN PF05479.11 EON96636.1 - 0.13 12.5 0.4 0.3 11.3 0.4 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) CLPTM1 PF05602.12 EON96637.1 - 6.3e-157 523.0 0.0 7.6e-157 522.7 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) His_Phos_2 PF00328.22 EON96638.1 - 6.4e-33 114.6 0.0 9.7e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) tRNA-synt_1 PF00133.22 EON96639.1 - 3.2e-45 154.5 4.2 1.6e-17 63.0 0.2 6.2 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EON96639.1 - 1.6e-43 148.4 0.0 4.3e-43 147.0 0.0 1.7 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EON96639.1 - 1.5e-29 103.0 0.0 8.4e-21 74.2 0.0 4.2 3 1 1 4 4 4 4 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EON96639.1 - 5.4e-13 49.2 0.1 1.4e-12 47.9 0.1 1.6 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EON96639.1 - 0.0018 17.7 0.0 0.96 8.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Med10 PF09748.9 EON96639.1 - 0.052 13.5 0.1 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex Dynamin_M PF01031.20 EON96640.1 - 2e-99 332.4 0.0 3.5e-99 331.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EON96640.1 - 1.7e-56 190.9 0.0 3.5e-56 189.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EON96640.1 - 6.9e-30 103.1 8.4 7e-30 103.0 6.0 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EON96640.1 - 4.8e-05 23.4 0.2 0.00052 20.1 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2226 PF09987.9 EON96640.1 - 0.03 13.7 0.1 7.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2226) AAA_15 PF13175.6 EON96640.1 - 0.032 13.9 0.8 2.6 7.7 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain Actin PF00022.19 EON96641.1 - 1.3e-150 501.5 0.0 5.2e-150 499.6 0.0 1.7 1 1 0 1 1 1 1 Actin SMI1_KNR4 PF09346.10 EON96642.1 - 3.5e-31 108.4 0.0 5.8e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Sec16_C PF12931.7 EON96643.1 - 2.3e-101 339.5 0.0 3.5e-101 338.8 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 EON96643.1 - 2.3e-23 83.0 1.9 2e-18 67.1 0.1 2.9 1 1 1 2 2 2 2 Vesicle coat trafficking protein Sec16 mid-region DUF4892 PF16234.5 EON96643.1 - 0.041 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4892) Nup96 PF12110.8 EON96643.1 - 0.06 12.5 0.1 2.3 7.3 0.1 2.2 2 0 0 2 2 2 0 Nuclear protein 96 zf-RING_2 PF13639.6 EON96644.1 - 1.4e-09 38.1 2.2 1.4e-09 38.1 2.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EON96644.1 - 1.8e-07 30.9 1.4 1.8e-07 30.9 1.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EON96644.1 - 1.8e-06 27.7 6.5 5.4e-06 26.2 3.2 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EON96644.1 - 5.9e-06 26.1 1.2 5.9e-06 26.1 1.2 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 EON96644.1 - 9.2e-06 25.9 2.1 9.2e-06 25.9 2.1 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EON96644.1 - 3.2e-05 23.9 7.0 7.3e-05 22.7 0.2 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EON96644.1 - 3.6e-05 23.5 4.2 3.6e-05 23.5 4.2 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EON96644.1 - 0.00044 20.3 0.8 0.00044 20.3 0.8 1.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EON96644.1 - 0.00055 19.7 10.0 0.015 15.1 1.3 3.1 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EON96644.1 - 0.031 14.0 0.4 0.031 14.0 0.4 2.6 2 2 0 2 2 2 0 RING-like zinc finger YdjO PF14169.6 EON96644.1 - 0.043 13.6 2.1 9.6 6.0 0.0 3.1 3 0 0 3 3 3 0 Cold-inducible protein YdjO HCV_NS4a PF01006.20 EON96644.1 - 0.075 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a zf-C3HC4_4 PF15227.6 EON96644.1 - 0.13 12.5 0.3 0.13 12.5 0.3 2.9 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EON96644.1 - 0.15 11.9 1.9 0.37 10.7 1.9 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_9 PF14369.6 EON96644.1 - 0.43 10.9 4.4 39 4.6 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon zf-RING_4 PF14570.6 EON96644.1 - 0.61 9.9 7.3 0.14 12.0 2.4 2.3 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.10 EON96644.1 - 3.2 7.9 7.5 18 5.5 0.4 3.2 3 0 0 3 3 3 0 Zinc ribbon domain Trypan_PARP PF05887.11 EON96644.1 - 4.1 7.4 14.1 7.5 6.5 14.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-LITAF-like PF10601.9 EON96644.1 - 5.9 7.2 7.1 2 8.7 3.0 2.1 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain zf-Di19 PF05605.12 EON96644.1 - 6.1 7.2 8.9 27 5.2 0.1 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding RecR PF02132.15 EON96644.1 - 8 6.1 7.3 6.7 6.4 0.1 2.9 3 0 0 3 3 3 0 RecR protein zinc-ribbons_6 PF07191.12 EON96644.1 - 9.8 6.2 6.9 1.6 8.7 2.9 1.8 2 0 0 2 2 2 0 zinc-ribbons Glyco_hydro_63 PF03200.16 EON96645.1 - 1.5e-174 581.4 5.3 3e-174 580.4 0.9 2.7 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EON96645.1 - 2.3e-87 292.9 0.1 7.3e-87 291.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EON96645.1 - 0.00026 19.9 0.0 0.00046 19.1 0.0 1.3 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 EON96645.1 - 0.018 14.0 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase DER1 PF04511.15 EON96646.1 - 1.3e-05 25.2 0.2 1.5e-05 25.0 0.2 1.0 1 0 0 1 1 1 1 Der1-like family AA_permease_2 PF13520.6 EON96647.1 - 1.2e-60 205.5 42.4 1.6e-60 205.1 42.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EON96647.1 - 8.3e-26 90.6 29.9 8.3e-26 90.6 29.9 1.9 2 0 0 2 2 2 1 Amino acid permease UPF0220 PF05255.11 EON96648.1 - 5.4e-67 224.5 3.1 6.1e-67 224.3 3.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF5337 PF17272.2 EON96648.1 - 0.69 9.8 4.6 0.41 10.5 1.0 2.3 1 1 2 3 3 3 0 Family of unknown function (DUF5337) DUF3341 PF11821.8 EON96648.1 - 0.73 9.5 6.9 0.055 13.1 1.7 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3341) LTV PF04180.14 EON96649.1 - 4.9e-113 378.7 13.0 5.6e-113 378.6 13.0 1.0 1 0 0 1 1 1 1 Low temperature viability protein RabGAP-TBC PF00566.18 EON96650.1 - 6.5e-39 133.8 1.2 1.2e-38 133.0 1.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 EON96650.1 - 1.7e-07 30.9 0.0 0.007 15.9 0.0 3.2 3 0 0 3 3 3 2 Rab-binding domain (RBD) IATP PF04568.12 EON96650.1 - 0.2 12.1 0.9 0.54 10.7 0.9 1.7 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Proteasome PF00227.26 EON96651.1 - 3.8e-51 173.3 0.1 4.8e-51 172.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EON96651.1 - 2.2e-11 43.2 0.2 3.7e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ArgJ PF01960.18 EON96652.1 - 8e-146 485.6 0.8 9.2e-146 485.4 0.8 1.0 1 0 0 1 1 1 1 ArgJ family Fes1 PF08609.10 EON96653.1 - 2.3e-30 105.3 2.3 2.8e-30 105.1 0.5 2.0 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 EON96653.1 - 3.8e-06 26.7 0.1 0.042 14.1 0.0 3.1 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 EON96653.1 - 3.4e-05 24.2 0.1 0.019 15.5 0.0 3.2 2 1 1 3 3 3 2 HEAT-like repeat Arm PF00514.23 EON96653.1 - 4.9e-05 23.2 0.0 0.12 12.5 0.0 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EON96653.1 - 6.2e-05 23.3 0.1 0.0005 20.4 0.0 2.3 2 1 0 2 2 2 1 HEAT repeats adh_short_C2 PF13561.6 EON96654.1 - 1.5e-45 155.6 0.4 6.5e-29 101.1 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON96654.1 - 2.7e-31 108.6 0.2 2.3e-16 59.8 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 EON96654.1 - 1.9e-07 31.2 0.1 2.7e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EON96654.1 - 1.3e-05 24.5 0.0 1.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ThiF PF00899.21 EON96654.1 - 0.013 14.8 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 ThiF family Epimerase PF01370.21 EON96654.1 - 0.056 12.9 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Med6 PF04934.14 EON96655.1 - 1.8e-37 128.1 0.1 2.5e-37 127.6 0.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component zf-C2H2 PF00096.26 EON96656.1 - 3.3e-05 24.1 10.2 0.044 14.2 0.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EON96656.1 - 0.037 14.5 13.5 0.052 14.0 4.8 3.4 3 1 0 3 3 3 0 Zinc-finger double domain SpdB PF05122.13 EON96656.1 - 0.071 13.3 1.3 0.22 11.7 0.7 2.2 2 0 0 2 2 2 0 Mobile element transfer protein zf-H2C2_5 PF13909.6 EON96656.1 - 0.072 12.9 6.3 0.086 12.6 1.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain OrsD PF12013.8 EON96656.1 - 0.15 12.5 2.3 0.21 12.0 0.2 2.2 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 EON96656.1 - 0.15 12.9 8.9 5.9 8.0 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EON96656.1 - 0.2 11.8 2.5 0.29 11.3 2.5 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger DUF3684 PF12449.8 EON96657.1 - 0 1518.6 0.0 0 1518.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 EON96657.1 - 4.5e-05 23.3 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2156 PF09924.9 EON96657.1 - 0.03 13.3 2.8 0.057 12.4 2.8 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) Reprolysin_5 PF13688.6 EON96657.1 - 0.043 14.0 0.6 0.091 12.9 0.6 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Fe_dep_repr_C PF02742.15 EON96657.1 - 0.18 11.9 1.2 1.7 8.8 0.1 2.9 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain FH2 PF02181.23 EON96658.1 - 9.7e-85 284.9 9.3 9.7e-85 284.9 9.3 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EON96658.1 - 8.6e-61 204.8 0.0 3.7e-60 202.7 0.0 2.2 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EON96658.1 - 9.1e-55 185.3 6.0 8.3e-54 182.2 1.4 3.1 2 1 1 3 3 3 2 Diaphanous FH3 Domain Dna2 PF08696.11 EON96658.1 - 0.47 10.2 2.7 0.34 10.7 0.2 2.1 2 0 0 2 2 2 0 DNA replication factor Dna2 Pkinase PF00069.25 EON96659.1 - 4.6e-65 219.6 0.0 5.3e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON96659.1 - 1.1e-25 90.4 0.0 1.4e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EON96659.1 - 1.6e-06 27.7 0.0 8.8e-06 25.2 0.0 1.9 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 EON96659.1 - 0.002 18.1 0.1 0.011 15.7 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1229 PF06797.11 EON96659.1 - 0.0051 17.0 0.2 0.008 16.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1229) Kdo PF06293.14 EON96659.1 - 0.092 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EON96659.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EON96659.1 - 0.11 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase adh_short PF00106.25 EON96660.1 - 2.7e-20 72.7 0.1 5.1e-16 58.7 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON96660.1 - 1.6e-09 37.7 0.1 3e-07 30.2 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON96660.1 - 2.8e-06 27.4 0.1 4.3e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Hus1 PF04005.12 EON96661.1 - 4.1e-87 292.0 0.0 4.6e-87 291.8 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Cyclase PF04199.13 EON96662.1 - 1.1e-12 48.3 0.0 1.6e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Vps55 PF04133.14 EON96663.1 - 4.2e-47 158.9 8.0 4.8e-47 158.7 8.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 WD40 PF00400.32 EON96664.1 - 1.1e-13 51.4 1.3 2e-06 28.4 0.3 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat CLTH PF10607.9 EON96664.1 - 0.0014 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain ANAPC4_WD40 PF12894.7 EON96664.1 - 0.0021 18.3 0.1 0.25 11.6 0.1 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 EON96664.1 - 0.085 12.6 0.4 1.3 8.7 0.1 2.4 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Glyco_hydro_18 PF00704.28 EON96665.1 - 2.6e-15 57.0 0.0 4.6e-15 56.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.25 EON96666.1 - 5.5e-70 235.7 0.0 7.3e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON96666.1 - 2.2e-49 168.1 0.0 3e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EON96666.1 - 7.6e-06 25.0 0.0 1.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EON96666.1 - 1.9e-05 24.2 0.0 7.7e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EON96666.1 - 0.15 11.0 0.0 0.66 8.9 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain AMP-binding PF00501.28 EON96667.1 - 9.6e-59 199.0 0.0 1.8e-58 198.1 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EON96667.1 - 4e-54 183.5 0.0 1e-50 172.3 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EON96667.1 - 3.2e-12 46.4 0.0 9.8e-12 44.8 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EON96667.1 - 4.9e-09 35.6 0.0 9.9e-09 34.6 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 EON96667.1 - 1.6e-07 31.6 0.0 3.7e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EON96667.1 - 2.7e-05 25.1 0.0 0.00024 22.0 0.0 2.6 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 EON96667.1 - 0.00034 20.5 0.0 0.00091 19.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EON96667.1 - 0.0022 17.5 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EON96667.1 - 0.015 14.4 0.0 0.093 11.8 0.0 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 EON96667.1 - 0.022 14.3 0.1 0.039 13.5 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family DUF3384 PF11864.8 EON96668.1 - 6e-150 500.3 3.4 6e-150 500.3 3.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 EON96668.1 - 7.6e-53 178.8 0.0 1.9e-52 177.5 0.0 1.7 2 0 0 2 2 2 1 Rap/ran-GAP Tuberin PF03542.16 EON96668.1 - 3.5e-40 138.2 1.5 2.1e-35 122.5 0.0 3.5 3 0 0 3 3 3 2 Tuberin ComR_TPR PF18710.1 EON96668.1 - 0.35 10.4 1.5 5 6.6 0.2 2.4 2 0 0 2 2 2 0 ComR tetratricopeptide LSM PF01423.22 EON96669.1 - 7.7e-17 60.7 0.2 1.1e-16 60.2 0.2 1.3 1 0 0 1 1 1 1 LSM domain Ribosomal_S21e PF01249.18 EON96669.1 - 0.04 14.0 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S21e HA2 PF04408.23 EON96670.1 - 5.2e-23 81.4 2.0 5.3e-22 78.2 0.0 2.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EON96670.1 - 5.1e-13 49.3 0.0 4.7e-12 46.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EON96670.1 - 1.3e-12 47.9 0.0 2.9e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EON96670.1 - 1.4e-06 28.2 0.1 5.1e-06 26.4 0.1 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EON96670.1 - 0.00029 21.1 0.0 0.00094 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EON96670.1 - 0.00078 19.8 0.0 0.0019 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EON96670.1 - 0.0014 17.7 0.0 0.007 15.5 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein UPF0240 PF06784.11 EON96670.1 - 0.0071 16.4 4.3 0.015 15.4 4.3 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) AAA_30 PF13604.6 EON96670.1 - 0.016 14.9 0.3 0.041 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EON96670.1 - 0.02 14.3 0.0 0.059 12.8 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein FtsK_SpoIIIE PF01580.18 EON96670.1 - 0.037 13.4 0.2 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATPase PF06745.13 EON96670.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 EON96670.1 - 0.084 13.4 0.0 0.43 11.1 0.0 2.3 1 0 0 1 1 1 0 AAA domain DUF4614 PF15391.6 EON96670.1 - 4.3 7.3 10.7 11 6.0 10.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF1996 PF09362.10 EON96671.1 - 5.6e-80 268.7 0.1 7.5e-80 268.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) adh_short PF00106.25 EON96672.1 - 1.9e-18 66.7 0.1 2.9e-18 66.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON96672.1 - 7.2e-15 55.2 0.0 9.8e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EON96672.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Longin PF13774.6 EON96673.1 - 3.2e-26 91.2 0.1 6.1e-26 90.3 0.1 1.5 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EON96673.1 - 8.6e-15 54.3 0.1 1.7e-14 53.4 0.0 1.5 2 0 0 2 2 2 1 Synaptobrevin DUF5435 PF17503.2 EON96673.1 - 0.027 14.2 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5435) SLM4 PF16818.5 EON96673.1 - 0.15 12.0 1.1 1.1 9.2 0.1 2.5 1 1 1 3 3 3 0 Protein SLM4 DUF4404 PF14357.6 EON96673.1 - 0.23 12.1 0.9 12 6.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF1664 PF07889.12 EON96673.1 - 0.76 9.8 5.6 0.53 10.3 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) RF-1 PF00472.20 EON96675.1 - 3.8e-15 55.8 5.5 5.1e-15 55.4 5.5 1.1 1 0 0 1 1 1 1 RF-1 domain MMR_HSR1 PF01926.23 EON96676.1 - 1.2e-16 60.8 0.5 3.9e-15 55.9 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EON96676.1 - 1.6e-08 34.2 0.4 5.9e-06 25.9 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EON96676.1 - 4.2e-06 26.8 0.0 0.00087 19.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 EON96676.1 - 0.0021 17.4 0.1 0.0037 16.6 0.1 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EON96676.1 - 0.0052 16.9 2.2 0.12 12.4 0.5 3.1 3 1 1 4 4 4 1 Dynamin family TRAP_alpha PF03896.16 EON96676.1 - 0.085 12.0 2.4 0.34 10.1 3.1 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF5523 PF17661.1 EON96676.1 - 0.1 12.3 6.3 0.27 10.9 6.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5523) ASXH PF13919.6 EON96677.1 - 1.4e-39 135.3 4.3 2.7e-39 134.4 3.0 1.9 2 0 0 2 2 2 1 Asx homology domain Phosphoesterase PF04185.14 EON96678.1 - 4e-73 246.7 5.0 5e-73 246.3 5.0 1.1 1 0 0 1 1 1 1 Phosphoesterase family Lysine_decarbox PF03641.14 EON96679.1 - 1.9e-30 105.7 0.0 2.7e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EON96679.1 - 1e-05 25.1 2.5 6.1e-05 22.7 2.4 2.0 1 1 0 1 1 1 1 SLOG cluster4 family Aminotran_5 PF00266.19 EON96680.1 - 1.7e-31 109.5 0.0 6.8e-18 64.8 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V ABC_tran PF00005.27 EON96681.1 - 7.5e-15 55.7 0.0 8.2e-14 52.3 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON96681.1 - 7e-12 45.8 0.1 0.00014 21.8 0.2 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 EON96681.1 - 0.0011 16.7 0.1 0.0014 16.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 EON96681.1 - 0.0017 18.1 0.1 0.0032 17.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EON96681.1 - 0.0038 16.7 0.0 2.2 7.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EON96681.1 - 0.0085 16.6 0.0 0.013 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EON96681.1 - 0.024 14.9 1.2 0.043 14.1 0.4 1.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EON96681.1 - 0.029 14.1 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 EON96681.1 - 0.031 14.7 0.9 0.085 13.2 0.9 1.8 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 EON96681.1 - 0.052 13.3 0.1 0.077 12.7 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 EON96681.1 - 0.078 13.4 0.0 0.23 11.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EON96681.1 - 0.084 12.4 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EON96681.1 - 0.085 13.1 0.1 0.25 11.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EON96681.1 - 0.089 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase Arf PF00025.21 EON96681.1 - 0.11 12.0 0.3 0.25 10.8 0.3 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family SRP54 PF00448.22 EON96681.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 EON96681.1 - 0.13 10.8 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EON96681.1 - 0.15 12.3 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EON96681.1 - 0.2 11.6 0.2 0.33 10.8 0.2 1.3 1 0 0 1 1 1 0 NACHT domain SPT_ssu-like PF11779.8 EON96682.1 - 1.5e-20 72.5 7.7 2.2e-20 72.0 7.7 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Sec8_exocyst PF04048.14 EON96683.1 - 1.2e-46 158.1 0.0 3.2e-46 156.7 0.0 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EON96683.1 - 4.5e-09 36.0 0.4 1e-08 34.9 0.4 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex WD40 PF00400.32 EON96684.1 - 8e-12 45.5 0.0 0.077 13.9 0.1 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON96684.1 - 2.6e-05 24.4 0.1 3.2 8.1 0.0 4.0 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EON96684.1 - 0.0043 16.1 0.0 0.2 10.6 0.0 2.4 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4596 PF15363.6 EON96684.1 - 0.032 14.4 0.1 0.067 13.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) Chorismate_bind PF00425.18 EON96685.1 - 4.2e-52 177.3 0.1 4.9e-52 177.1 0.1 1.0 1 0 0 1 1 1 1 chorismate binding enzyme CAS_CSE1 PF03378.15 EON96687.1 - 5.1e-185 615.2 0.0 1.3e-184 613.9 0.0 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 EON96687.1 - 1.3e-155 517.8 0.4 3.7e-155 516.3 1.0 1.4 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.19 EON96687.1 - 1.9e-12 46.9 0.1 5.2e-12 45.5 0.1 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EON96687.1 - 0.0035 17.4 1.0 0.032 14.3 0.1 3.1 3 0 0 3 3 3 1 Exportin 1-like protein DUF1529 PF07485.11 EON96687.1 - 0.0036 17.2 0.0 0.0095 15.8 0.0 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1259) TRAPPC9-Trs120 PF08626.11 EON96688.1 - 1.8e-194 648.4 0.0 2e-194 648.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Ribosomal_L5_C PF00673.21 EON96689.1 - 4.8e-28 97.2 0.0 8.8e-28 96.3 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EON96689.1 - 3.2e-08 33.8 0.0 5.2e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Urm1 PF09138.11 EON96690.1 - 1e-33 115.5 0.0 1.2e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EON96690.1 - 0.0075 16.9 0.0 0.0094 16.6 0.0 1.2 1 0 0 1 1 1 1 ThiS family DnaJ PF00226.31 EON96691.1 - 0.058 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain CoA_transf_3 PF02515.17 EON96692.1 - 9.7e-70 235.5 0.0 1.2e-69 235.2 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Transp_cyt_pur PF02133.15 EON96694.1 - 7.9e-07 28.2 0.4 8.8e-07 28.0 0.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sulfotransfer_4 PF17784.1 EON96695.1 - 1.1e-21 77.7 1.3 2.2e-17 63.6 0.5 2.0 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EON96695.1 - 0.002 18.6 0.1 0.0028 18.1 0.1 1.3 1 1 0 1 1 1 1 Sulfotransferase family Transp_cyt_pur PF02133.15 EON96696.1 - 1.1e-16 60.7 4.7 1.2e-16 60.5 4.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2236 PF09995.9 EON96698.1 - 8.4e-11 42.5 2.8 1.1e-10 42.1 2.8 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) adh_short PF00106.25 EON96701.1 - 0.00026 20.5 0.0 0.00032 20.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON96701.1 - 0.065 12.8 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.19 EON96701.1 - 0.13 11.6 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain p450 PF00067.22 EON96703.1 - 3.4e-41 141.5 0.2 2e-24 86.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF3328 PF11807.8 EON96705.1 - 4.2e-21 75.8 0.3 7.1e-21 75.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TPP_enzyme_N PF02776.18 EON96706.1 - 7.6e-36 123.3 0.0 1.6e-34 119.0 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EON96706.1 - 1.3e-24 86.7 0.2 3.4e-23 82.1 0.0 3.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EON96706.1 - 2.1e-23 82.6 0.0 4.5e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Sugar_tr PF00083.24 EON96707.1 - 1.7e-79 267.8 24.6 1.9e-79 267.7 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON96707.1 - 4.1e-16 58.9 51.2 2.6e-15 56.2 28.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.21 EON96708.1 - 6.9e-41 140.4 1.8 1e-40 139.8 1.8 1.2 1 0 0 1 1 1 1 POT family CcmH PF03918.14 EON96708.1 - 0.1 11.9 0.0 0.43 9.9 0.0 1.9 2 0 0 2 2 2 0 Cytochrome C biogenesis protein adh_short PF00106.25 EON96709.1 - 4.2e-40 137.3 0.0 5.9e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON96709.1 - 8.9e-23 81.1 0.0 1.2e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON96709.1 - 2.6e-07 30.7 0.1 5.7e-07 29.6 0.1 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EON96709.1 - 0.00061 19.7 0.0 0.0011 18.9 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding LytR_C PF13399.6 EON96709.1 - 0.0083 17.1 0.3 0.018 16.0 0.3 1.5 1 0 0 1 1 1 1 LytR cell envelope-related transcriptional attenuator Polysacc_synt_2 PF02719.15 EON96709.1 - 0.016 14.4 0.1 0.021 13.9 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 EON96709.1 - 0.016 15.1 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 EON96709.1 - 0.051 13.5 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF4038 PF13204.6 EON96709.1 - 0.059 13.0 0.0 0.095 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Shikimate_DH PF01488.20 EON96709.1 - 0.059 13.4 0.1 0.15 12.1 0.1 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_tran_WecB PF03808.13 EON96709.1 - 0.069 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Sacchrp_dh_NADP PF03435.18 EON96709.1 - 0.075 13.3 0.1 0.23 11.7 0.1 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EON96709.1 - 0.16 12.6 0.0 0.33 11.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Myb_DNA-binding PF00249.31 EON96710.1 - 1.8e-09 37.6 0.0 9.4e-09 35.3 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM PF04433.17 EON96710.1 - 1.5e-06 28.5 0.0 4.8e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain SHOCT PF09851.9 EON96710.1 - 0.026 14.2 0.6 0.1 12.4 0.6 2.1 1 0 0 1 1 1 0 Short C-terminal domain Mt_ATP-synt_D PF05873.12 EON96710.1 - 0.4 10.5 4.1 1.8 8.4 0.3 2.7 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) TPR_1 PF00515.28 EON96711.1 - 0.00076 19.2 1.2 0.45 10.4 2.9 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EON96711.1 - 0.0017 18.6 0.4 0.0035 17.6 0.4 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EON96711.1 - 0.0018 18.7 2.2 0.0022 18.5 1.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 EON96711.1 - 0.002 18.9 6.3 0.002 18.9 6.3 1.7 2 0 0 2 2 2 1 CHIP N-terminal tetratricopeptide repeat domain TPR_2 PF07719.17 EON96711.1 - 0.002 18.1 4.0 0.018 15.1 3.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EON96711.1 - 0.0052 17.0 0.2 0.011 16.1 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EON96711.1 - 0.027 14.5 0.5 0.28 11.3 0.3 2.2 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat U-box PF04564.15 EON96711.1 - 0.054 13.7 0.1 0.094 12.9 0.1 1.4 1 0 0 1 1 1 0 U-box domain TPR_14 PF13428.6 EON96711.1 - 0.21 12.5 1.8 0.55 11.2 0.7 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat PhyH PF05721.13 EON96712.1 - 4.1e-17 63.1 0.0 5.1e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) GalP_UDP_transf PF01087.22 EON96713.1 - 1.3e-71 240.8 0.1 1.1e-70 237.8 0.0 2.0 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 EON96713.1 - 1.1e-58 197.7 0.0 2e-58 196.8 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 EON96713.1 - 1.1e-05 26.1 0.0 0.00051 20.7 0.0 2.5 2 1 0 2 2 2 1 HIT domain HTH_ParB PF17762.1 EON96713.1 - 0.023 14.5 0.2 0.042 13.6 0.2 1.4 1 0 0 1 1 1 0 HTH domain found in ParB protein WG_beta_rep PF14903.6 EON96713.1 - 0.16 12.2 0.1 0.43 10.9 0.1 1.7 1 0 0 1 1 1 0 WG containing repeat FAD_binding_4 PF01565.23 EON96715.1 - 2.8e-20 72.5 0.4 4.2e-20 71.9 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EON96715.1 - 0.012 15.7 1.4 0.018 15.2 0.2 2.0 2 0 0 2 2 2 0 Berberine and berberine like ECH_1 PF00378.20 EON96716.1 - 3.5e-54 183.8 0.0 5e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON96716.1 - 2.8e-27 96.1 0.0 9.1e-27 94.4 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase adh_short_C2 PF13561.6 EON96717.1 - 2.7e-41 141.7 3.3 6.3e-30 104.5 2.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON96717.1 - 3.9e-31 108.0 2.7 5.5e-31 107.6 2.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 EON96717.1 - 0.032 14.1 1.9 0.038 13.9 0.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 EON96717.1 - 0.062 14.0 0.1 0.14 12.9 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S8 PF00082.22 EON96718.1 - 3.3e-18 66.0 0.1 8.9e-15 54.7 0.1 2.4 2 1 0 2 2 2 2 Subtilase family DNA_ligase_C PF17879.1 EON96718.1 - 0.018 15.1 0.1 3.7 7.6 0.0 2.5 2 0 0 2 2 2 0 DNA ligase C-terminal domain PHO4 PF01384.20 EON96719.1 - 1.2e-59 202.1 0.5 1.4e-59 201.9 0.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family MFS_1 PF07690.16 EON96720.1 - 7.9e-17 61.2 15.7 1.9e-08 33.7 5.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EON96720.1 - 0.0026 16.7 3.5 0.0037 16.2 3.5 1.2 1 0 0 1 1 1 1 MFS_1 like family Glyco_hydro_28 PF00295.17 EON96721.1 - 5.2e-34 117.8 0.4 8.7e-19 67.7 0.6 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 PWI PF01480.17 EON96722.1 - 4.7e-14 52.4 1.4 7.2e-14 51.9 0.1 2.0 2 0 0 2 2 2 1 PWI domain Mg_trans_NIPA PF05653.14 EON96724.1 - 1.9e-89 299.7 27.7 2.6e-89 299.2 27.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EON96724.1 - 2.1e-05 24.7 7.6 2.1e-05 24.7 7.6 3.1 3 0 0 3 3 3 1 EamA-like transporter family DUF5362 PF17319.2 EON96724.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5362) DUF805 PF05656.14 EON96724.1 - 0.45 11.0 13.6 1.1 9.7 3.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF805) USP19_linker PF16602.5 EON96724.1 - 1.5 9.4 6.9 2 9.0 0.2 3.2 3 0 0 3 3 3 0 Linker region of USP19 deubiquitinase DUF3433 PF11915.8 EON96725.1 - 2.9e-19 69.3 5.8 2.9e-19 69.3 5.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) Nucleoporin_N PF08801.11 EON96726.1 - 1.9e-93 313.6 0.0 2.5e-93 313.2 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EON96726.1 - 1.1e-51 176.3 0.4 4.2e-50 171.1 0.0 2.0 1 1 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal DUF1824 PF08854.10 EON96726.1 - 0.073 13.0 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) ABC_membrane PF00664.23 EON96727.1 - 4e-83 279.2 25.9 4.4e-48 164.3 15.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EON96727.1 - 1e-30 107.1 0.2 3.6e-30 105.3 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EON96727.1 - 6.8e-07 28.9 2.2 0.0001 21.9 2.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EON96727.1 - 0.0013 18.4 0.3 0.0036 17.0 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EON96727.1 - 0.0028 16.5 0.1 0.23 10.2 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_15 PF13175.6 EON96727.1 - 0.02 14.6 0.1 0.058 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 EON96727.1 - 0.041 13.7 0.1 0.13 12.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EON96727.1 - 0.054 13.9 0.0 0.15 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EON96727.1 - 0.057 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 EON96727.1 - 0.058 13.9 0.3 0.15 12.5 0.3 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EON96727.1 - 0.062 13.6 0.3 0.52 10.6 0.3 2.2 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EON96727.1 - 0.57 10.4 3.4 1.8 8.9 0.2 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Abhydrolase_1 PF00561.20 EON96728.1 - 5.3e-11 42.6 0.0 4.1e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON96728.1 - 8.5e-09 36.3 0.0 2.3e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON96728.1 - 1.8e-06 27.4 0.0 1.4e-05 24.5 0.0 2.2 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DUF4286 PF14114.6 EON96728.1 - 6.3e-05 23.4 0.0 0.041 14.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4286) Esterase PF00756.20 EON96728.1 - 0.0028 17.3 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase EthD PF07110.11 EON96728.1 - 0.0029 18.7 0.0 0.3 12.3 0.0 2.6 2 0 0 2 2 2 1 EthD domain Abhydrolase_2 PF02230.16 EON96728.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Pho88 PF10032.9 EON96729.1 - 1.1e-83 279.0 0.1 1.3e-83 278.8 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) TMEMspv1-c74-12 PF11044.8 EON96729.1 - 0.62 10.1 3.3 0.83 9.7 0.1 2.6 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein XPA_C PF05181.12 EON96730.1 - 7.8e-25 86.6 1.7 7.8e-25 86.6 1.7 1.9 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.18 EON96730.1 - 0.018 15.1 10.0 0.018 15.1 10.0 2.3 3 0 0 3 3 3 0 XPA protein N-terminal ArfGap PF01412.18 EON96730.1 - 1.7 8.7 7.8 0.21 11.7 2.8 2.0 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Striatin PF08232.12 EON96731.1 - 4.9e-42 144.1 7.7 9.2e-42 143.3 7.7 1.5 1 0 0 1 1 1 1 Striatin family WD40 PF00400.32 EON96731.1 - 6.5e-23 80.6 19.3 1.3e-05 25.8 0.0 7.7 8 1 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON96731.1 - 0.00033 20.9 0.0 0.81 10.0 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EON96731.1 - 0.11 11.4 0.0 0.96 8.3 0.0 2.3 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4482 PF14818.6 EON96731.1 - 7.5 7.4 9.2 1.9 9.4 5.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) MFS_1 PF07690.16 EON96732.1 - 1.3e-30 106.5 18.8 1.6e-30 106.2 18.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON96732.1 - 3.8e-13 49.1 2.3 5.5e-13 48.6 2.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EON96732.1 - 0.00046 18.7 4.9 0.00064 18.3 4.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UL42 PF17638.2 EON96732.1 - 0.065 13.2 0.2 0.18 11.8 0.2 1.7 1 0 0 1 1 1 0 HCMV UL42 Transp_cyt_pur PF02133.15 EON96734.1 - 1.9e-14 53.3 4.1 2.4e-14 53.0 4.1 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sugar_tr PF00083.24 EON96735.1 - 1.5e-76 258.1 28.3 1.7e-76 257.9 28.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON96735.1 - 3.3e-21 75.6 31.6 3e-17 62.6 9.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EON96735.1 - 1.3 7.7 24.2 0.91 8.3 8.7 2.6 2 1 1 3 3 3 0 MFS_1 like family FAD_binding_4 PF01565.23 EON96736.1 - 8.7e-11 41.7 0.2 1.6e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EON96736.1 - 0.025 14.7 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like CFEM PF05730.11 EON96737.1 - 2.9e-11 43.3 4.5 2.9e-11 43.3 4.5 2.8 3 1 0 3 3 3 1 CFEM domain RdRP PF05183.12 EON96738.1 - 2.8e-165 551.3 0.0 1.5e-152 509.3 0.0 2.0 1 1 1 2 2 2 2 RNA dependent RNA polymerase NAD_binding_8 PF13450.6 EON96739.1 - 1.2e-12 47.8 0.0 2.4e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EON96739.1 - 3.5e-09 36.5 0.4 6.3e-09 35.7 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EON96739.1 - 5.7e-09 35.8 0.0 8.7e-05 22.0 0.0 2.1 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EON96739.1 - 3.3e-06 26.4 0.3 4.6e-06 26.0 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EON96739.1 - 3.8e-06 25.9 0.1 6.4e-06 25.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EON96739.1 - 4.3e-05 23.3 0.5 6.9e-05 22.6 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON96739.1 - 0.00021 20.6 0.0 0.00035 19.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON96739.1 - 0.00044 19.6 0.0 0.0007 18.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EON96739.1 - 0.00074 19.2 0.2 0.0023 17.6 0.2 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 EON96739.1 - 0.0011 19.5 0.0 0.0025 18.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EON96739.1 - 0.0013 18.1 0.2 0.0018 17.6 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EON96739.1 - 0.0033 16.7 0.0 0.0058 15.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EON96739.1 - 0.0059 15.7 0.1 0.0094 15.1 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A DpaA_N PF16924.5 EON96739.1 - 0.027 14.5 0.0 4.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain NAD_binding_9 PF13454.6 EON96739.1 - 0.086 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EON96739.1 - 0.1 11.5 0.1 0.16 10.8 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.23 EON96739.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus peroxidase PF00141.23 EON96740.1 - 8.7e-30 104.1 0.0 1.4e-29 103.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 EON96740.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Fungal peroxidase extension region Amidase PF01425.21 EON96741.1 - 1.8e-67 228.2 0.3 2.6e-67 227.7 0.3 1.1 1 0 0 1 1 1 1 Amidase R3H PF01424.22 EON96742.1 - 3.6e-11 42.9 0.0 6.8e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 EON96742.1 - 6.4e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 EON96742.1 - 0.19 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif 2 Abhydrolase_6 PF12697.7 EON96743.1 - 1.4e-13 51.9 0.8 1.9e-13 51.6 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON96743.1 - 7.4e-12 45.5 0.1 4.1e-07 29.9 0.0 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON96743.1 - 1e-10 41.3 0.0 1.6e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EON96743.1 - 0.0049 15.6 0.0 0.026 13.2 0.0 1.9 1 1 0 1 1 1 1 Ndr family Ribosomal_S19 PF00203.21 EON96745.1 - 1.8e-27 95.0 0.0 2.1e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Ge1_WD40 PF16529.5 EON96746.1 - 0.15 11.0 0.0 1.5 7.7 0.0 2.5 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2294 PF10057.9 EON96746.1 - 0.25 11.5 1.4 1.6 8.9 0.2 2.6 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) YpjP PF14005.6 EON96746.1 - 0.66 10.0 7.3 1.4 9.0 0.2 3.8 2 1 1 3 3 3 0 YpjP-like protein HEAT_2 PF13646.6 EON96746.1 - 8.4 6.9 9.3 6 7.3 5.1 2.8 2 0 0 2 2 2 0 HEAT repeats ANAPC10 PF03256.16 EON96747.1 - 1.8e-06 27.7 0.0 2.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) adh_short PF00106.25 EON96748.1 - 4.3e-42 143.8 0.0 5.5e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON96748.1 - 1.3e-26 93.6 0.0 1.8e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON96748.1 - 1.8e-07 31.3 0.1 4.2e-07 30.1 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EON96748.1 - 0.00014 21.4 0.1 0.00046 19.7 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EON96748.1 - 0.0007 19.5 0.0 0.00084 19.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EON96748.1 - 0.041 13.4 0.4 0.098 12.2 0.2 1.7 2 0 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.17 EON96748.1 - 0.041 13.0 0.1 0.059 12.5 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EON96748.1 - 0.06 12.5 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EON96748.1 - 0.08 12.3 0.1 0.24 10.8 0.1 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase OST3_OST6 PF04756.13 EON96748.1 - 0.1 12.0 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF3842 PF12953.7 EON96748.1 - 0.17 12.3 1.8 0.32 11.4 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3842) Peptidase_S8 PF00082.22 EON96749.1 - 1.5e-45 155.8 3.3 2.4e-45 155.1 3.3 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EON96749.1 - 5.7e-11 43.1 0.0 1.2e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain Cellulase PF00150.18 EON96750.1 - 1.4e-52 178.8 5.5 1.8e-52 178.5 5.5 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 EON96750.1 - 0.00072 19.3 0.1 0.00092 18.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) EthD PF07110.11 EON96751.1 - 0.0023 19.1 0.0 0.0026 18.9 0.0 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 EON96751.1 - 0.034 14.6 0.0 0.036 14.5 0.0 1.2 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase DNA_pol_A_exoN PF18305.1 EON96751.1 - 0.1 12.9 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain Mre11_DNA_bind PF04152.14 EON96752.1 - 8.2e-52 175.9 1.7 8.2e-52 175.9 1.7 2.1 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EON96752.1 - 3.7e-16 60.3 2.7 8.2e-16 59.1 2.3 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EON96752.1 - 1.1e-05 25.7 0.0 6e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain BC10 PF06726.12 EON96753.1 - 3.5e-17 62.4 11.2 6e-17 61.6 11.2 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Transp_cyt_pur PF02133.15 EON96754.1 - 1e-44 153.0 14.9 1.4e-44 152.6 14.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Peptidase_C47 PF05543.13 EON96754.1 - 0.0065 16.1 0.3 0.012 15.3 0.3 1.3 1 0 0 1 1 1 1 Staphopain peptidase C47 ANAPC10 PF03256.16 EON96755.1 - 3.1e-23 82.4 0.0 3.6e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) GTP_CH_N PF12471.8 EON96756.1 - 3.7e-89 297.6 0.0 5.1e-89 297.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EON96756.1 - 1.8e-17 63.4 0.0 3.3e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II PhyH PF05721.13 EON96757.1 - 1.1e-14 55.3 0.0 1.4e-14 54.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Na_Ca_ex PF01699.24 EON96758.1 - 1.4e-22 80.3 28.7 7.6e-16 58.4 12.0 3.6 4 0 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 EON96758.1 - 6.4e-18 65.2 11.4 6.4e-18 65.2 11.4 3.8 6 0 0 6 6 6 1 Inner membrane component domain Y_phosphatase PF00102.27 EON96759.1 - 1e-58 198.7 0.0 1.2e-33 116.6 0.0 3.8 3 1 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.20 EON96759.1 - 2e-12 47.6 0.0 6.8e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 EON96759.1 - 0.023 14.5 0.1 0.054 13.3 0.1 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EON96759.1 - 0.036 14.0 0.1 0.079 12.9 0.1 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family MFS_1 PF07690.16 EON96760.1 - 5.1e-10 38.8 25.3 5.7e-09 35.4 25.3 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily SNAPc_SNAP43 PF09808.9 EON96760.1 - 0.042 13.8 0.3 0.075 13.0 0.1 1.5 1 1 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DUF687 PF05095.12 EON96760.1 - 0.066 11.7 0.2 0.095 11.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF687) S_4TM PF18159.1 EON96760.1 - 0.12 11.6 1.3 0.56 9.4 0.6 2.1 1 1 1 2 2 2 0 SMODS-associating 4TM effector domain DUF2140 PF09911.9 EON96760.1 - 0.14 11.7 0.2 0.26 10.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) HlyIII PF03006.20 EON96760.1 - 1.8 8.2 14.2 0.68 9.6 8.1 2.2 2 1 0 2 2 2 0 Haemolysin-III related Histone PF00125.24 EON96761.1 - 4.6e-18 65.9 0.0 5.9e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EON96761.1 - 9.7e-13 47.6 0.1 2.5e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EON96761.1 - 2.6e-05 24.4 0.0 3.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone AAA PF00004.29 EON96762.1 - 7.6e-44 149.3 0.0 1.3e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EON96762.1 - 2.2e-14 53.0 0.0 4.3e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EON96762.1 - 1.1e-07 31.9 0.0 2.7e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EON96762.1 - 1.3e-07 31.9 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EON96762.1 - 4.4e-06 27.2 0.0 0.00011 22.6 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 EON96762.1 - 2.4e-05 24.2 2.5 6.4e-05 22.8 2.5 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EON96762.1 - 2.5e-05 24.6 0.2 0.006 16.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EON96762.1 - 5.8e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EON96762.1 - 0.00063 20.3 0.0 0.019 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EON96762.1 - 0.001 18.4 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EON96762.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EON96762.1 - 0.0028 17.4 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EON96762.1 - 0.0032 17.3 0.0 0.01 15.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_OB_N PF17758.1 EON96762.1 - 0.0053 16.4 0.1 0.018 14.7 0.1 1.9 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain Mg_chelatase PF01078.21 EON96762.1 - 0.008 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EON96762.1 - 0.0085 15.5 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 KaiC TsaE PF02367.17 EON96762.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EON96762.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EON96762.1 - 0.021 14.0 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EON96762.1 - 0.023 14.4 0.0 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EON96762.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EON96762.1 - 0.029 13.8 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 EON96762.1 - 0.032 14.3 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EON96762.1 - 0.032 13.9 0.0 0.1 12.3 0.0 1.8 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 EON96762.1 - 0.034 14.5 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase HR1 PF02185.16 EON96762.1 - 0.051 13.7 1.0 0.13 12.4 1.0 1.7 1 0 0 1 1 1 0 Hr1 repeat AAA_25 PF13481.6 EON96762.1 - 0.054 13.1 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EON96762.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.9 EON96762.1 - 0.067 13.5 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Zeta_toxin PF06414.12 EON96762.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Phosphoesterase PF04185.14 EON96763.1 - 4.8e-34 118.1 2.9 2.9e-33 115.5 2.8 1.9 1 1 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.23 EON96763.1 - 0.025 14.0 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Sulfatase SMYLE_N PF18615.1 EON96763.1 - 0.073 12.6 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain TFIID_30kDa PF03540.13 EON96764.1 - 2e-25 88.5 0.4 3.2e-25 87.8 0.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TAF4 PF05236.14 EON96764.1 - 0.24 11.1 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Rep_fac_C PF08542.11 EON96765.1 - 5.2e-16 58.8 0.0 1.4e-15 57.5 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EON96765.1 - 1e-15 58.3 0.0 1.7e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EON96765.1 - 2.3e-12 47.0 0.0 9.1e-12 45.0 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EON96765.1 - 1.8e-09 37.8 0.0 3.3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 EON96765.1 - 3.1e-07 30.3 0.0 5.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EON96765.1 - 1.9e-06 28.2 0.0 4.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EON96765.1 - 2.1e-06 27.8 0.1 0.00015 21.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EON96765.1 - 2.6e-06 27.9 0.0 1.1e-05 25.9 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EON96765.1 - 1.3e-05 25.3 0.4 5.3e-05 23.2 0.1 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EON96765.1 - 1.9e-05 24.4 0.0 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EON96765.1 - 7.2e-05 23.2 0.0 0.00018 21.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EON96765.1 - 0.00014 21.2 0.0 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EON96765.1 - 0.00019 21.2 0.0 0.00061 19.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 EON96765.1 - 0.00024 20.8 0.0 0.00043 20.0 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 EON96765.1 - 0.0004 20.4 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 EON96765.1 - 0.00054 19.8 0.0 0.00097 19.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 EON96765.1 - 0.00088 18.7 0.1 0.0056 16.1 0.1 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EON96765.1 - 0.0011 18.8 0.1 0.0054 16.6 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EON96765.1 - 0.0012 18.3 0.0 0.41 10.1 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein AAA_18 PF13238.6 EON96765.1 - 0.0032 18.0 0.0 0.0054 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EON96765.1 - 0.0034 17.4 0.0 0.052 13.5 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.6 EON96765.1 - 0.0035 17.6 0.0 0.0062 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EON96765.1 - 0.0082 15.6 0.0 0.065 12.6 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein DEAD PF00270.29 EON96765.1 - 0.013 15.3 0.1 0.095 12.5 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_7 PF12775.7 EON96765.1 - 0.021 14.3 0.0 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 EON96765.1 - 0.036 13.3 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 EON96765.1 - 0.046 13.3 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EON96765.1 - 0.096 13.1 0.0 0.2 12.0 0.0 1.7 1 1 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 EON96765.1 - 0.15 11.9 0.0 0.35 10.8 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NTP_transf_6 PF06042.11 EON96766.1 - 5.9e-53 179.0 0.0 7.1e-53 178.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase Glyco_hydro_75 PF07335.11 EON96767.1 - 9.1e-59 198.4 0.1 1.1e-58 198.2 0.1 1.0 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 DUF1688 PF07958.11 EON96768.1 - 8.9e-165 548.5 0.0 1e-164 548.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) AAA_2 PF07724.14 EON96768.1 - 0.097 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Methyltransf_23 PF13489.6 EON96769.1 - 4.4e-19 68.9 0.0 6e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON96769.1 - 2e-14 54.1 0.0 9.2e-14 51.9 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON96769.1 - 9.5e-14 51.8 0.0 1.8e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON96769.1 - 1.2e-09 38.8 0.0 1.8e-08 35.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON96769.1 - 1.7e-09 37.6 0.0 0.0011 18.8 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 EON96769.1 - 2.4e-05 23.8 0.0 0.00059 19.2 0.0 2.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EON96769.1 - 0.00064 19.2 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EON96769.1 - 0.0047 16.5 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EON96769.1 - 0.0094 15.7 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 EON96769.1 - 0.022 14.0 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 EON96769.1 - 0.038 14.1 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 EON96769.1 - 0.047 13.1 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Glyco_hydro_3_C PF01915.22 EON96770.1 - 1.4e-38 132.9 0.0 5.6e-38 130.9 0.0 2.1 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EON96770.1 - 6.5e-37 127.6 0.0 1.1e-36 126.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EON96770.1 - 2.6e-25 88.3 0.4 4.5e-25 87.5 0.4 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain V_ATPase_I PF01496.19 EON96771.1 - 0.14 10.0 12.1 0.42 8.5 12.1 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3209 PF11483.8 EON96771.1 - 2.6 8.5 5.7 1.2 9.6 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3209) adh_short PF00106.25 EON96772.1 - 3.7e-27 95.0 0.0 5.1e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON96772.1 - 6.9e-20 71.6 0.0 9.5e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON96772.1 - 6.7e-05 22.9 0.0 9.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF3216 PF11505.8 EON96772.1 - 0.089 13.0 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) SLD5_C PF16922.5 EON96774.1 - 1.2e-12 47.8 0.0 2e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EON96774.1 - 1.9e-08 34.7 0.5 1.2e-07 32.2 0.3 2.1 2 0 0 2 2 2 1 GINS complex protein TRPM_tetra PF16519.5 EON96774.1 - 0.033 14.3 0.3 0.064 13.4 0.3 1.5 1 0 0 1 1 1 0 Tetramerisation domain of TRPM DUF2290 PF10053.9 EON96774.1 - 0.085 12.3 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2290) RPW8 PF05659.11 EON96774.1 - 0.16 11.7 0.1 0.38 10.4 0.1 1.7 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 VDE PF07137.11 EON96775.1 - 0.046 13.2 4.6 0.064 12.8 4.6 1.3 1 0 0 1 1 1 0 VDE lipocalin domain zf-Tim10_DDP PF02953.15 EON96775.1 - 4.3 7.1 6.7 0.59 9.8 0.2 2.5 1 1 2 3 3 3 0 Tim10/DDP family zinc finger F-box PF00646.33 EON96776.1 - 5.2e-06 26.2 1.7 1.1e-05 25.2 1.7 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EON96776.1 - 0.0012 18.7 2.0 0.0017 18.2 0.7 2.0 2 0 0 2 2 2 1 F-box-like Ecl1 PF12855.7 EON96776.1 - 0.54 11.4 4.3 1.6 9.8 4.3 1.8 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Glyco_hydro_79C PF16862.5 EON96777.1 - 2.6e-15 57.1 0.1 6.8e-15 55.8 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain adh_short PF00106.25 EON96778.1 - 1.4e-30 106.2 0.0 3.6e-30 104.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON96778.1 - 1.2e-19 70.8 0.0 1.4e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON96778.1 - 1.2e-12 48.1 0.2 1.9e-12 47.5 0.2 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EON96778.1 - 0.00071 19.1 0.0 0.00092 18.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EON96778.1 - 0.0053 16.2 0.0 0.0077 15.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EON96778.1 - 0.0094 15.9 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EON96778.1 - 0.036 13.2 0.2 0.059 12.5 0.2 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Aldolase_II PF00596.21 EON96779.1 - 2.9e-40 138.2 0.0 4.1e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Aldedh PF00171.22 EON96780.1 - 5.7e-135 450.4 0.1 6.7e-135 450.2 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EON96780.1 - 0.061 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) FAD_binding_3 PF01494.19 EON96781.1 - 8.4e-80 268.6 0.0 1e-79 268.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EON96781.1 - 2.2e-29 102.6 0.0 4.2e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EON96781.1 - 6.9e-07 28.8 0.0 0.00031 20.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON96781.1 - 1e-05 26.0 0.0 0.0022 18.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON96781.1 - 0.00015 20.6 0.2 0.00026 19.8 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 EON96781.1 - 0.0005 19.2 0.5 0.0011 18.1 0.2 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EON96781.1 - 0.00055 20.1 0.1 0.0013 18.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EON96781.1 - 0.002 17.5 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EON96781.1 - 0.0028 17.3 0.0 0.014 15.0 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EON96781.1 - 0.0047 16.1 0.1 0.0091 15.1 0.0 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 EON96781.1 - 0.0057 15.5 0.0 0.0093 14.9 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.24 EON96781.1 - 0.011 14.8 0.1 0.021 13.9 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain XdhC_C PF13478.6 EON96781.1 - 0.018 15.5 0.0 0.043 14.3 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.14 EON96781.1 - 0.019 14.5 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EON96781.1 - 0.021 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 EON96781.1 - 0.028 13.8 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.6 EON96781.1 - 0.032 13.5 0.0 0.066 12.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EON96781.1 - 0.039 13.3 0.4 0.076 12.3 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 EON96781.1 - 0.052 12.8 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EON96781.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding SE PF08491.10 EON96781.1 - 0.18 10.8 0.0 0.39 9.7 0.0 1.5 1 1 0 1 1 1 0 Squalene epoxidase Calreticulin PF00262.18 EON96783.1 - 2.6e-166 553.0 18.2 3.4e-166 552.6 18.2 1.2 1 0 0 1 1 1 1 Calreticulin family SseC PF04888.12 EON96783.1 - 0.0066 16.1 1.6 0.0066 16.1 1.6 1.6 2 0 0 2 2 2 1 Secretion system effector C (SseC) like family DUF1911 PF08929.10 EON96783.1 - 0.051 14.4 0.5 0.52 11.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1911) NAD_binding_4 PF07993.12 EON96784.1 - 3.9e-13 49.2 0.3 3.3e-08 33.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 EON96784.1 - 4.5e-11 42.3 0.0 7.1e-11 41.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EON96784.1 - 8.7e-11 41.7 0.1 4.5e-10 39.4 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EON96784.1 - 7e-10 39.1 0.1 1.1e-09 38.4 0.1 1.3 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EON96784.1 - 2e-06 27.5 0.3 2.9e-06 27.0 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EON96784.1 - 0.00013 21.5 0.0 0.0003 20.3 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EON96784.1 - 0.00034 20.6 0.5 2.1 8.2 0.1 3.1 3 0 0 3 3 3 1 KR domain Polysacc_synt_2 PF02719.15 EON96784.1 - 0.0047 16.1 0.0 0.0078 15.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Polysacc_lyase PF14099.6 EON96784.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide lyase ATP11 PF06644.11 EON96785.1 - 2.4e-103 345.6 0.0 2.8e-103 345.5 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein DUF3827 PF12877.7 EON96785.1 - 0.038 12.4 0.0 0.05 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) TPR_14 PF13428.6 EON96786.1 - 2.6e-05 24.6 0.3 0.85 10.6 0.0 5.9 5 2 3 8 8 8 1 Tetratricopeptide repeat Suf PF05843.14 EON96786.1 - 0.00017 21.7 12.4 0.46 10.4 0.2 3.8 3 1 1 4 4 4 3 Suppressor of forked protein (Suf) Prefoldin PF02996.17 EON96787.1 - 4.5e-24 84.7 0.1 6.4e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Cep57_MT_bd PF06657.13 EON96787.1 - 0.0085 16.5 0.3 0.017 15.6 0.3 1.5 1 0 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 Fib_alpha PF08702.10 EON96787.1 - 0.023 14.9 0.2 4.3 7.5 0.0 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GIT_CC PF16559.5 EON96787.1 - 0.023 14.6 2.1 0.034 14.0 0.8 1.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DASH_Dam1 PF08653.10 EON96787.1 - 0.023 14.5 0.2 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 Prefoldin_2 PF01920.20 EON96787.1 - 0.023 14.6 0.7 5.8 6.9 0.4 2.2 2 0 0 2 2 2 0 Prefoldin subunit UvsW PF11637.8 EON96787.1 - 0.028 14.5 0.1 0.072 13.2 0.1 1.7 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW Fzo_mitofusin PF04799.13 EON96787.1 - 0.033 13.8 0.4 3.7 7.1 0.1 2.1 2 0 0 2 2 2 0 fzo-like conserved region DUF1664 PF07889.12 EON96787.1 - 0.063 13.3 1.9 1.6 8.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ApoO PF09769.9 EON96787.1 - 0.2 11.6 0.2 5.5 7.0 0.1 2.1 2 0 0 2 2 2 0 Apolipoprotein O Tektin PF03148.14 EON96787.1 - 0.36 9.5 2.3 3.1 6.5 0.4 2.0 2 0 0 2 2 2 0 Tektin family DUF3852 PF12963.7 EON96788.1 - 0.62 10.4 3.0 1.3 9.4 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3852) KH_1 PF00013.29 EON96789.1 - 2.6e-42 142.5 6.9 3.2e-18 65.3 0.7 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EON96789.1 - 4.6e-13 48.8 4.6 0.0046 16.7 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EON96789.1 - 1.4e-06 28.1 0.6 0.31 10.9 0.1 3.5 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 EON96789.1 - 3.7e-05 23.6 0.0 0.0097 15.9 0.0 2.8 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 EON96789.1 - 0.0029 17.7 11.1 0.34 11.0 0.3 3.7 4 0 0 4 4 4 2 NusA-like KH domain Lipase_3 PF01764.25 EON96790.1 - 4.4e-29 101.2 0.0 6.2e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EON96790.1 - 6.3e-06 25.6 0.0 9.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON96790.1 - 0.00016 22.3 0.1 0.00023 21.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EON96790.1 - 0.0048 17.0 0.0 0.0078 16.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF2974 PF11187.8 EON96790.1 - 0.0052 16.4 0.2 0.049 13.2 0.0 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 EON96790.1 - 0.053 13.2 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EON96790.1 - 0.068 12.9 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 EON96790.1 - 0.28 10.6 0.0 0.42 10.1 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) BTB PF00651.31 EON96791.1 - 0.012 15.8 0.1 0.036 14.3 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain ABC_transp_aux PF09822.9 EON96791.1 - 0.017 14.6 0.0 0.053 13.0 0.0 1.7 2 0 0 2 2 2 0 ABC-type uncharacterized transport system Dynamin_M PF01031.20 EON96792.1 - 4.3e-111 370.7 0.0 9.1e-111 369.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EON96792.1 - 5.7e-56 189.2 0.5 1.4e-55 187.9 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 EON96792.1 - 4.9e-31 106.7 1.6 1.6e-30 105.1 1.6 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EON96792.1 - 4.4e-05 23.5 0.2 0.00058 19.9 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Cu-oxidase_3 PF07732.15 EON96793.1 - 1.9e-42 144.0 0.9 1.9e-42 144.0 0.9 3.1 4 1 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EON96793.1 - 1.6e-37 128.3 0.5 1.1e-32 112.6 0.0 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EON96793.1 - 1.6e-27 96.6 0.0 3.6e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase LapA_dom PF06305.11 EON96793.1 - 0.5 10.2 1.4 1 9.2 1.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain CLLAC PF15675.5 EON96793.1 - 1.4 8.6 5.8 2.3 7.9 5.8 1.3 1 0 0 1 1 1 0 CLLAC-motif containing domain DUF1752 PF08550.10 EON96794.1 - 1.8e-13 50.1 3.8 4.5e-13 48.8 3.8 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF4611 PF15387.6 EON96794.1 - 0.072 13.3 5.0 0.36 11.1 0.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) GHL13 PF14883.6 EON96794.1 - 0.19 10.8 0.4 10 5.1 0.1 2.6 3 0 0 3 3 3 0 Hypothetical glycosyl hydrolase family 13 PBP1_TM PF14812.6 EON96794.1 - 2.1 8.8 6.5 15 6.0 0.4 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Abhydrolase_6 PF12697.7 EON96795.1 - 9.5e-16 59.1 0.4 1.2e-15 58.7 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON96795.1 - 0.00057 19.6 0.1 0.0016 18.1 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON96795.1 - 0.023 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Sep15_SelM PF08806.11 EON96795.1 - 0.23 11.6 0.1 4.2 7.6 0.0 2.6 2 1 1 3 3 3 0 Sep15/SelM redox domain Glyco_hydro_15 PF00723.21 EON96796.1 - 7e-51 173.4 0.0 3.2e-48 164.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 SBDS PF01172.18 EON96797.1 - 6.5e-25 87.0 0.5 7.8e-25 86.8 0.5 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF4827 PF16109.5 EON96797.1 - 0.012 15.6 0.2 0.016 15.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4827) CENP-P PF13096.6 EON96797.1 - 0.056 13.1 0.0 0.077 12.7 0.0 1.1 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P RNA_ligase PF09414.10 EON96798.1 - 3.3e-32 112.0 0.0 4.5e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 RNA ligase RNA_lig_T4_1 PF09511.10 EON96798.1 - 0.033 14.0 0.0 0.066 13.1 0.0 1.5 1 1 0 1 1 1 0 RNA ligase RWD PF05773.22 EON96799.1 - 3.9e-16 59.4 0.1 6.8e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 EON96799.1 - 8.2e-07 29.4 6.1 1.7e-06 28.4 6.1 1.5 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF2852 PF11014.8 EON96799.1 - 0.01 16.0 1.9 0.016 15.4 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) MPM1 PF17234.2 EON96799.1 - 2 8.6 4.7 3.1 8.0 4.3 1.5 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 PMT PF02366.18 EON96800.1 - 3.9e-82 275.5 15.3 7.1e-82 274.7 15.3 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EON96800.1 - 4.2e-69 232.1 8.1 4.2e-69 232.1 8.1 3.2 4 1 0 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EON96800.1 - 4e-20 72.4 4.6 8.9e-20 71.3 1.2 1.8 1 1 1 2 2 2 2 MIR domain p450 PF00067.22 EON96801.1 - 3.3e-72 243.7 0.0 6.1e-72 242.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 VWA_2 PF13519.6 EON96802.1 - 5.4e-27 94.5 1.5 7.1e-27 94.2 0.1 1.9 2 1 1 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 EON96802.1 - 2e-10 41.2 0.3 2.7e-10 40.8 0.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 EON96802.1 - 1.4e-07 31.5 0.0 2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 EON96802.1 - 0.0075 16.1 1.1 0.022 14.6 1.1 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif DNA_pol3_a_NII PF11490.8 EON96802.1 - 0.18 11.7 4.0 0.12 12.3 1.7 1.8 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II FYDLN_acid PF09538.10 EON96802.1 - 2.4 8.9 9.8 6.3 7.5 9.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Pkinase PF00069.25 EON96803.1 - 5.4e-67 225.9 0.0 7.6e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON96803.1 - 1.2e-38 132.8 0.0 1.8e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EON96803.1 - 1.9e-07 30.7 0.0 1.2e-06 28.0 0.0 2.0 1 1 1 2 2 2 1 Kinase-like POLO_box PF00659.18 EON96803.1 - 1.3e-06 28.5 0.1 0.00088 19.4 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.14 EON96803.1 - 0.00048 19.5 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EON96803.1 - 0.0049 15.7 0.3 0.012 14.4 0.1 1.7 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EON96803.1 - 0.13 11.1 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain CBF PF03914.17 EON96804.1 - 7.7e-54 182.3 1.8 9.3e-54 182.0 0.1 2.2 2 0 0 2 2 2 1 CBF/Mak21 family Mo25 PF08569.11 EON96804.1 - 0.046 13.1 0.5 0.096 12.0 0.0 1.7 2 0 0 2 2 2 0 Mo25-like BUD22 PF09073.10 EON96804.1 - 0.052 12.9 45.5 0.057 12.7 15.4 2.7 2 0 0 2 2 2 0 BUD22 DUF2789 PF10982.8 EON96804.1 - 0.21 11.7 1.1 14 5.9 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2789) Nbl1_Borealin_N PF10444.9 EON96805.1 - 2.1e-20 72.1 5.2 2.9e-20 71.6 5.2 1.2 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Peptidase_S10 PF00450.22 EON96806.1 - 8.9e-18 64.9 0.0 1e-17 64.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase tRNA-synt_2b PF00587.25 EON96807.1 - 6.9e-27 94.6 0.0 5.5e-26 91.6 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EON96807.1 - 3e-08 33.7 0.0 5.3e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain TPR_8 PF13181.6 EON96808.1 - 2.2e-09 36.8 0.2 0.00015 21.7 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EON96808.1 - 6e-09 36.3 13.5 0.00059 20.3 3.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EON96808.1 - 1.3e-08 34.3 4.4 0.003 17.6 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EON96808.1 - 1.6e-08 35.1 17.7 0.0042 17.7 6.5 4.8 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EON96808.1 - 1.6e-07 31.5 10.7 0.0037 17.5 0.0 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EON96808.1 - 7.5e-07 28.8 3.9 0.0046 16.9 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EON96808.1 - 0.00039 20.6 0.9 0.052 13.8 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EON96808.1 - 0.00041 20.1 0.1 0.042 13.7 0.1 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EON96808.1 - 0.0085 16.8 23.7 0.066 14.1 0.1 5.8 5 3 1 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EON96808.1 - 0.0091 16.1 14.2 0.37 11.0 0.0 5.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 EON96808.1 - 7.9 6.5 11.5 8.2 6.4 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat FAM27 PF15832.5 EON96809.1 - 2.5 8.7 16.5 2.3 8.8 0.6 2.4 2 0 0 2 2 2 0 FAM27 D and E protein family Choline_kinase PF01633.20 EON96810.1 - 3.1e-53 180.5 0.0 1.9e-52 177.9 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EON96810.1 - 2.3e-11 44.1 0.4 6.8e-11 42.5 0.4 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EON96810.1 - 0.0003 20.2 0.0 0.0009 18.6 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EON96810.1 - 0.065 12.1 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kin_N PF04428.14 EON96810.1 - 0.11 12.2 0.0 0.92 9.2 0.0 2.1 2 0 0 2 2 2 0 Choline kinase N terminus LRR_6 PF13516.6 EON96811.1 - 3.2e-10 39.2 12.3 0.00022 21.0 0.0 6.9 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 EON96811.1 - 3.3e-07 30.5 13.7 0.08 13.4 0.0 5.3 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EON96811.1 - 4.7e-06 26.4 1.9 7.5 7.5 0.1 5.7 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 EON96811.1 - 1.7e-05 24.5 12.4 0.59 9.9 0.1 5.2 3 1 0 4 4 4 3 Leucine rich repeat V-ATPase_C PF03223.15 EON96812.1 - 1.5e-125 419.5 0.0 1.8e-125 419.2 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.15 EON96812.1 - 0.028 15.1 0.3 0.077 13.6 0.1 1.8 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain RRM_1 PF00076.22 EON96813.1 - 1.2e-41 140.3 0.1 1.1e-20 73.1 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EON96813.1 - 0.013 15.6 0.1 1.5 9.0 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif RRM_Rrp7 PF17799.1 EON96813.1 - 0.023 14.5 0.7 0.93 9.3 0.0 3.1 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain Keratin_2_head PF16208.5 EON96813.1 - 0.3 11.2 34.7 0.87 9.7 34.7 1.8 1 0 0 1 1 1 0 Keratin type II head Baculo_PEP_C PF04513.12 EON96815.1 - 2.3e-05 24.5 6.0 0.0029 17.6 1.1 2.4 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 EON96815.1 - 0.18 12.3 5.1 0.17 12.3 0.8 2.5 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-K PF11802.8 EON96816.1 - 4.1e-13 49.5 1.1 2.6e-06 27.2 2.8 2.3 2 0 0 2 2 2 2 Centromere-associated protein K BAR_3 PF16746.5 EON96816.1 - 0.0053 16.5 3.6 0.0053 16.5 3.6 1.7 2 0 0 2 2 2 1 BAR domain of APPL family SpoU_sub_bind PF08032.12 EON96816.1 - 0.02 15.2 1.3 0.042 14.1 0.0 2.1 2 1 1 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding PIN_8 PF18476.1 EON96816.1 - 0.12 12.2 12.6 0.054 13.3 8.2 2.1 1 1 1 2 2 2 0 PIN like domain Borrelia_REV PF03978.13 EON96816.1 - 2.3 8.2 7.6 7.9 6.4 0.5 2.5 1 1 1 2 2 2 0 Borrelia burgdorferi REV protein DUF1664 PF07889.12 EON96816.1 - 2.8 8.0 6.8 0.47 10.5 1.6 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 EON96816.1 - 4.2 8.0 9.1 4.3 8.0 0.8 3.7 2 1 2 4 4 4 0 Syntaxin 6, N-terminal Atg14 PF10186.9 EON96816.1 - 6.1 5.8 12.4 0.28 10.2 6.4 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-H2C2_2 PF13465.6 EON96817.1 - 2e-06 27.9 10.0 3.4e-06 27.2 1.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EON96817.1 - 2.3e-05 24.2 0.5 0.063 13.3 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EON96817.1 - 2.6e-05 24.4 0.3 2.6e-05 24.4 0.3 3.5 3 1 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 EON96817.1 - 7.8e-05 23.2 10.6 0.15 12.7 0.0 3.6 3 1 1 4 4 4 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 EON96817.1 - 0.0038 18.0 7.5 0.012 16.3 0.3 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger TSCPD PF12637.7 EON96817.1 - 0.083 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 TSCPD domain zf-H2C2_5 PF13909.6 EON96817.1 - 0.47 10.3 1.9 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain CPL PF08144.11 EON96818.1 - 1.2e-45 155.4 0.0 2.6e-44 151.0 0.0 2.9 3 0 0 3 3 3 1 CPL (NUC119) domain Hexokinase_1 PF00349.21 EON96818.1 - 0.0088 16.0 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Hexokinase DUF3206 PF11472.8 EON96818.1 - 0.056 13.4 0.0 2.8 7.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3206) TraH_2 PF06871.11 EON96818.1 - 5.6 6.6 6.0 1.4 8.5 0.1 2.2 2 0 0 2 2 2 0 TraH_2 Proteasome PF00227.26 EON96819.1 - 4.9e-39 133.8 0.0 5.7e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Atg14 PF10186.9 EON96820.1 - 0.079 12.0 9.7 0.13 11.4 9.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 La PF05383.17 EON96821.1 - 3.3e-16 59.1 0.1 5.4e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 La domain FMO-like PF00743.19 EON96822.1 - 2.5e-10 39.4 0.3 7.6e-09 34.5 0.1 2.7 2 2 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EON96822.1 - 2.8e-09 37.1 0.0 1.2e-08 35.0 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EON96822.1 - 0.00081 18.7 0.0 0.031 13.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON96822.1 - 0.018 14.2 0.0 1.3 8.1 0.0 3.0 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EON96822.1 - 0.069 12.4 0.0 0.75 9.0 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FMN_dh PF01070.18 EON96823.1 - 1.5e-110 369.6 0.0 1.9e-110 369.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 EON96823.1 - 4.7e-07 29.5 0.7 6.9e-07 29.0 0.7 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 EON96823.1 - 5.7e-05 22.4 0.2 8.9e-05 21.8 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 EON96823.1 - 6.7e-05 22.3 0.2 0.1 11.9 0.3 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EON96823.1 - 0.00031 19.9 1.8 0.00062 18.9 0.8 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain IGPS PF00218.21 EON96823.1 - 0.018 14.2 0.0 0.041 13.1 0.0 1.5 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 EON96823.1 - 0.019 14.5 0.1 0.13 11.7 0.0 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein ABC_tran PF00005.27 EON96824.1 - 3e-34 118.5 0.0 4.6e-16 59.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 EON96824.1 - 8.2e-14 51.1 5.2 8.2e-14 51.1 5.2 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 EON96824.1 - 2.7e-12 46.6 0.8 0.00023 20.7 0.1 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EON96824.1 - 2.6e-10 40.6 8.4 0.087 12.6 0.1 4.4 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EON96824.1 - 3.2e-06 27.6 0.0 0.049 14.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 EON96824.1 - 1.5e-05 24.9 0.3 0.14 11.9 0.0 3.2 3 1 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EON96824.1 - 2e-05 24.9 0.0 0.004 17.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EON96824.1 - 2.5e-05 24.7 0.0 0.024 15.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Fer4 PF00037.27 EON96824.1 - 6.6e-05 22.5 2.8 6.6e-05 22.5 2.8 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_10 PF13237.6 EON96824.1 - 0.00017 21.7 8.8 0.0064 16.6 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_18 PF13238.6 EON96824.1 - 0.00034 21.2 0.1 1.6 9.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 EON96824.1 - 0.00037 20.4 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EON96824.1 - 0.00042 20.0 0.1 0.47 10.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Rad17 PF03215.15 EON96824.1 - 0.0005 20.0 0.2 0.059 13.3 0.0 2.8 2 1 1 3 3 3 1 Rad17 P-loop domain RNA_helicase PF00910.22 EON96824.1 - 0.00067 20.0 0.5 0.32 11.4 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_24 PF13479.6 EON96824.1 - 0.00094 18.9 0.1 0.26 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EON96824.1 - 0.00099 18.8 2.5 0.045 13.4 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_6 PF12837.7 EON96824.1 - 0.0021 18.1 12.0 0.0034 17.4 1.6 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain NACHT PF05729.12 EON96824.1 - 0.0021 18.0 1.0 0.21 11.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Fer4_21 PF14697.6 EON96824.1 - 0.0025 17.9 10.8 0.0053 16.9 10.8 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 EON96824.1 - 0.0027 17.4 0.3 3.8 7.1 0.0 2.9 3 0 0 3 3 2 2 Thymidylate kinase AAA_23 PF13476.6 EON96824.1 - 0.0029 18.1 3.8 0.052 14.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EON96824.1 - 0.0042 16.3 0.0 0.27 10.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 EON96824.1 - 0.0044 17.2 0.1 0.63 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EON96824.1 - 0.0063 16.5 0.0 0.065 13.2 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 EON96824.1 - 0.0072 15.0 0.0 0.0072 15.0 0.0 2.7 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.14 EON96824.1 - 0.012 15.6 0.6 0.4 10.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EON96824.1 - 0.014 14.9 0.3 0.25 10.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Fer4_7 PF12838.7 EON96824.1 - 0.015 15.9 7.1 0.018 15.7 0.4 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_30 PF13604.6 EON96824.1 - 0.02 14.6 0.1 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EON96824.1 - 0.023 14.9 0.6 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EON96824.1 - 0.083 12.8 1.3 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 NTPase Fer4_16 PF13484.6 EON96824.1 - 0.083 13.8 0.3 0.083 13.8 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 EON96824.1 - 0.084 13.1 10.7 0.18 12.0 10.7 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain VirE PF05272.11 EON96824.1 - 0.14 11.9 0.0 8 6.1 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_17 PF13534.6 EON96824.1 - 0.15 12.6 0.2 0.15 12.6 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_14 PF13173.6 EON96824.1 - 0.17 11.9 0.6 24 5.0 0.0 3.2 2 1 0 3 3 3 0 AAA domain Fer4_8 PF13183.6 EON96824.1 - 0.2 12.1 0.2 0.2 12.1 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain PduV-EutP PF10662.9 EON96824.1 - 0.32 10.7 4.0 0.66 9.7 0.1 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EON96824.1 - 0.33 11.0 1.6 24 5.0 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase CLP1_P PF16575.5 EON96824.1 - 0.35 10.6 1.2 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Fer4_2 PF12797.7 EON96824.1 - 2.1 8.6 9.6 0.31 11.2 1.0 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Methyltransf_16 PF10294.9 EON96825.1 - 0.0097 15.7 0.0 0.059 13.1 0.0 2.0 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EON96825.1 - 0.18 11.6 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ATP_sub_h PF10775.9 EON96826.1 - 9.1e-26 89.7 1.0 1.4e-25 89.1 1.0 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h Formyl_trans_N PF00551.19 EON96827.1 - 2.2e-40 138.3 0.0 3e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Lum_binding PF00677.17 EON96828.1 - 1.1e-46 156.7 2.1 6.1e-23 80.6 0.2 2.1 2 0 0 2 2 2 2 Lumazine binding domain Methyltransf_11 PF08241.12 EON96829.1 - 5.2e-14 52.7 0.0 1.3e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON96829.1 - 1.2e-07 32.3 0.0 3e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON96829.1 - 4.8e-05 23.3 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON96829.1 - 0.00088 20.0 0.0 0.0019 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON96829.1 - 0.025 13.9 0.0 0.063 12.6 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 EON96829.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_31 PF13847.6 EON96829.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 EON96830.1 - 1.6e-69 234.2 0.0 2e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON96830.1 - 1.1e-31 110.0 0.0 1.6e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EON96830.1 - 0.0014 19.3 0.7 0.0041 17.8 0.7 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EON96830.1 - 0.0034 16.4 0.0 0.005 15.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EON96830.1 - 0.049 12.4 0.0 0.086 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EON96830.1 - 0.071 12.4 0.1 0.18 11.1 0.0 1.7 1 1 1 2 2 2 0 Kinase-like APH PF01636.23 EON96830.1 - 0.17 11.7 0.2 1.8 8.4 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family dNK PF01712.19 EON96831.1 - 0.044 13.6 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 Deoxynucleoside kinase E1-E2_ATPase PF00122.20 EON96832.1 - 4.6e-50 169.7 5.4 8.9e-50 168.7 1.6 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EON96832.1 - 1e-45 155.7 8.0 1.1e-45 155.6 6.6 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EON96832.1 - 2.3e-24 86.9 0.3 4.2e-20 72.9 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EON96832.1 - 2e-20 72.6 0.0 3.7e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EON96832.1 - 2.1e-17 62.6 0.0 5.5e-17 61.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EON96832.1 - 2.2e-08 34.2 0.9 5.6e-06 26.3 0.9 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EON96832.1 - 1.6e-05 25.4 0.0 6.5e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ABC_tran PF00005.27 EON96833.1 - 1.7e-55 187.3 0.0 2.6e-32 112.2 0.0 3.2 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EON96833.1 - 1.3e-38 133.2 20.2 1.6e-27 96.9 12.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EON96833.1 - 2.2e-08 33.8 1.6 0.025 14.0 0.1 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EON96833.1 - 4.2e-07 30.3 0.4 2.1 8.6 0.0 4.8 5 0 0 5 5 4 2 AAA domain AAA_29 PF13555.6 EON96833.1 - 1.8e-06 27.6 0.3 0.045 13.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EON96833.1 - 2.7e-06 28.0 0.2 0.0091 16.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EON96833.1 - 3.6e-05 23.4 0.2 0.38 10.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 EON96833.1 - 5.6e-05 23.4 4.6 0.0064 16.6 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 EON96833.1 - 0.00012 22.2 0.2 0.091 12.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EON96833.1 - 0.00012 22.0 0.0 0.35 10.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EON96833.1 - 0.00015 21.7 5.0 0.64 9.8 0.2 4.2 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 EON96833.1 - 0.00055 19.1 0.6 0.13 11.3 0.1 2.9 3 0 0 3 3 3 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 EON96833.1 - 0.0047 16.2 0.1 0.55 9.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.22 EON96833.1 - 0.0053 16.0 1.0 1.4 8.1 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain NACHT PF05729.12 EON96833.1 - 0.021 14.7 1.2 1.2 9.1 0.3 2.5 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 EON96833.1 - 0.044 13.5 0.3 15 5.2 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_15 PF13175.6 EON96833.1 - 0.054 13.2 1.3 3.6 7.2 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain MeaB PF03308.16 EON96833.1 - 0.061 12.3 0.1 0.71 8.8 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Sigma54_activat PF00158.26 EON96833.1 - 0.062 13.0 0.0 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EON96833.1 - 0.093 12.2 0.3 8.6 5.8 0.0 2.9 3 0 0 3 3 3 0 P-loop containing dynein motor region DUF2075 PF09848.9 EON96833.1 - 0.094 11.9 1.0 0.6 9.3 0.1 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EON96833.1 - 0.14 12.5 9.3 3.2 8.1 0.6 3.9 3 1 1 4 4 4 0 AAA ATPase domain ABC_tran PF00005.27 EON96834.1 - 3.3e-35 121.6 0.0 6.6e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EON96834.1 - 9.9e-22 77.9 11.1 1.3e-21 77.5 11.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EON96834.1 - 2e-05 24.1 0.0 9.7e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EON96834.1 - 0.0027 17.5 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EON96834.1 - 0.005 16.8 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 EON96834.1 - 0.0057 16.5 0.1 0.015 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 EON96834.1 - 0.015 14.6 0.0 0.039 13.2 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 EON96834.1 - 0.018 15.0 0.1 0.037 13.9 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_23 PF13476.6 EON96834.1 - 0.038 14.5 0.1 0.075 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EON96834.1 - 0.043 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EON96834.1 - 0.079 13.2 0.0 0.22 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EON96834.1 - 0.14 12.4 0.2 1 9.7 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 EON96834.1 - 0.17 11.5 0.0 0.42 10.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain HSP20 PF00011.21 EON96835.1 - 6.7e-19 67.9 0.2 1.4e-13 50.8 0.1 2.6 2 1 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EON96835.1 - 4.3e-06 26.2 0.0 0.0038 16.7 0.0 2.2 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Ribosomal_L36e PF01158.18 EON96836.1 - 8.5e-42 141.3 5.6 9.6e-42 141.2 5.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e MRP-L28 PF09812.9 EON96836.1 - 0.056 13.6 1.8 0.05 13.7 1.0 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L28 PBS_linker_poly PF00427.21 EON96836.1 - 0.078 13.0 0.1 0.089 12.8 0.1 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide SUI1 PF01253.22 EON96837.1 - 1e-25 90.1 0.5 2.4e-25 88.8 0.5 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.14 EON96837.1 - 0.00077 19.7 0.6 0.0017 18.6 0.2 1.8 2 1 0 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) TnpV PF14198.6 EON96837.1 - 0.023 14.7 0.2 0.044 13.8 0.2 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpV SpoIIE PF07228.12 EON96838.1 - 7.7e-11 42.3 0.1 3.4e-10 40.1 0.1 1.8 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EON96838.1 - 2.9e-09 36.9 0.0 4.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 EON96838.1 - 1.9e-06 27.7 0.0 0.02 14.6 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C RRM_1 PF00076.22 EON96839.1 - 9.8e-16 57.3 0.0 2.1e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Stm1_N PF09598.10 EON96839.1 - 0.03 15.2 4.9 0.03 15.2 4.9 3.4 4 0 0 4 4 4 0 Stm1 Ras PF00071.22 EON96840.1 - 3.6e-49 166.5 0.0 4.4e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EON96840.1 - 9e-30 103.4 0.1 2.2e-29 102.1 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EON96840.1 - 1.3e-10 41.0 0.0 1.7e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EON96840.1 - 0.00018 21.5 0.0 0.00032 20.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EON96840.1 - 0.00055 20.3 0.1 0.003 17.9 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 EON96840.1 - 0.0022 17.4 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 EON96840.1 - 0.018 14.5 0.1 0.033 13.6 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 EON96840.1 - 0.019 14.1 2.4 0.88 8.7 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit RsgA_GTPase PF03193.16 EON96840.1 - 0.02 14.8 0.1 5.4 6.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 EON96840.1 - 0.024 14.2 0.1 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 EON96840.1 - 0.058 13.4 0.1 0.12 12.3 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EON96840.1 - 0.061 13.1 0.1 0.098 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EON96840.1 - 0.084 12.3 0.0 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EON96840.1 - 0.093 13.1 0.1 0.2 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 EON96840.1 - 0.1 12.7 0.2 0.21 11.8 0.2 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EON96840.1 - 0.18 11.1 0.3 0.26 10.6 0.3 1.2 1 0 0 1 1 1 0 KaiC Septin PF00735.18 EON96840.1 - 0.18 11.1 0.6 0.25 10.6 0.1 1.5 2 0 0 2 2 2 0 Septin Cytochrom_C1 PF02167.15 EON96841.1 - 4.3e-93 311.0 0.0 5.3e-93 310.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EON96841.1 - 0.0092 16.3 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III 4HBT PF03061.22 EON96842.1 - 7.9e-10 39.0 0.0 1.6e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily SR-25 PF10500.9 EON96843.1 - 0.013 15.1 1.5 0.013 15.1 1.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3439 PF11921.8 EON96843.1 - 0.055 13.4 11.4 0.12 12.3 11.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 EON96843.1 - 0.074 11.3 12.5 0.1 10.8 12.5 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3807 PF12720.7 EON96843.1 - 0.082 13.2 38.2 0.44 10.8 26.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) BAF1_ABF1 PF04684.13 EON96843.1 - 0.088 11.9 22.6 0.11 11.6 22.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NST1 PF13945.6 EON96843.1 - 0.12 12.5 44.2 0.46 10.6 30.3 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator TFIIA PF03153.13 EON96843.1 - 0.24 11.3 41.5 0.32 10.9 41.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_polI_A34 PF08208.11 EON96843.1 - 0.68 10.0 39.6 0.08 13.0 4.1 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Sec62 PF03839.16 EON96843.1 - 2.8 7.4 27.7 1.9 7.9 19.5 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 FAM76 PF16046.5 EON96843.1 - 3.5 6.9 31.6 3 7.1 21.4 2.1 2 0 0 2 2 2 0 FAM76 protein PTPRCAP PF15713.5 EON96843.1 - 6.1 7.1 33.4 2 8.7 0.2 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated NARP1 PF12569.8 EON96843.1 - 6.3 5.6 37.8 1.3 7.8 2.1 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF1764 PF08576.10 EON96843.1 - 6.6 7.7 36.4 7.7 7.5 4.0 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Sporozoite_P67 PF05642.11 EON96843.1 - 8.5 4.3 27.9 0.036 12.2 4.9 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen adh_short_C2 PF13561.6 EON96844.1 - 1.7e-55 188.2 0.0 2.3e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON96844.1 - 8.6e-43 146.1 0.0 1.1e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON96844.1 - 3.5e-12 46.6 0.0 4.6e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EON96844.1 - 0.082 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) PALP PF00291.25 EON96844.1 - 0.086 12.2 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF4205 PF13898.6 EON96844.1 - 0.1 11.5 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) RNase_PH PF01138.21 EON96845.1 - 1e-10 42.2 0.0 1.8e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EON96845.1 - 0.003 17.5 0.0 0.0056 16.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 zf-Nse PF11789.8 EON96846.1 - 0.082 12.7 1.0 0.26 11.1 0.1 2.3 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit NAD_kinase PF01513.21 EON96847.1 - 3.2e-80 269.5 0.0 4.2e-80 269.1 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase GlutR_dimer PF00745.20 EON96847.1 - 0.049 14.1 0.8 0.11 12.9 0.8 1.6 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain ABC_membrane PF00664.23 EON96848.1 - 9.8e-81 271.4 36.7 1.3e-45 156.2 14.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EON96848.1 - 7.7e-64 214.3 0.0 9.7e-32 110.3 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EON96848.1 - 3e-12 46.4 10.6 0.00017 21.1 4.1 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EON96848.1 - 1.7e-09 38.1 0.1 0.0078 16.5 0.0 4.2 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.6 EON96848.1 - 5.5e-08 32.4 1.4 0.001 18.7 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EON96848.1 - 1.5e-06 27.3 0.4 0.061 12.1 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 EON96848.1 - 2.8e-06 27.4 0.0 0.033 14.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 EON96848.1 - 3.3e-06 27.0 0.4 0.056 13.1 0.1 3.3 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.6 EON96848.1 - 3.6e-06 27.6 1.1 0.023 15.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 EON96848.1 - 7.5e-06 26.4 2.7 0.1 13.0 0.3 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 EON96848.1 - 9.1e-06 25.6 0.0 0.026 14.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EON96848.1 - 1.3e-05 25.2 0.2 0.17 11.7 0.1 3.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EON96848.1 - 0.00031 20.4 0.8 1.2 8.7 0.1 3.2 4 0 0 4 4 2 2 AAA domain SbcCD_C PF13558.6 EON96848.1 - 0.00081 19.6 2.6 1.3 9.4 0.2 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 EON96848.1 - 0.0024 17.6 0.0 1 9.0 0.0 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 EON96848.1 - 0.0029 17.6 0.0 3.7 7.5 0.0 3.3 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EON96848.1 - 0.0031 17.0 0.0 2.4 7.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 EON96848.1 - 0.01 16.0 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EON96848.1 - 0.012 16.0 2.5 39 4.7 0.2 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EON96848.1 - 0.012 16.1 0.0 8.8 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EON96848.1 - 0.012 15.4 0.1 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 EON96848.1 - 0.018 14.4 0.0 0.85 8.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF3987 PF13148.6 EON96848.1 - 0.028 13.4 0.3 0.09 11.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_24 PF13479.6 EON96848.1 - 0.037 13.7 0.2 12 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EON96848.1 - 0.047 13.3 0.1 6.4 6.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.17 EON96848.1 - 0.06 13.4 0.4 5.8 7.0 0.1 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_14 PF13173.6 EON96848.1 - 0.06 13.4 0.0 5.6 7.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EON96848.1 - 0.097 12.9 0.0 10 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EON96848.1 - 0.13 11.4 0.1 6.2 5.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Roc PF08477.13 EON96848.1 - 0.17 12.1 0.1 16 5.8 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 EON96848.1 - 0.19 11.6 0.0 6.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain TM_helix PF05552.12 EON96848.1 - 0.2 11.6 9.7 4.6 7.3 1.9 3.7 3 0 0 3 3 3 0 Conserved TM helix DUF3094 PF11293.8 EON96848.1 - 0.94 9.2 4.1 24 4.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) Methyltransf_25 PF13649.6 EON96849.1 - 2.1e-10 41.1 0.0 4.5e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EON96849.1 - 8.2e-10 38.5 0.0 1.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EON96849.1 - 3.9e-09 36.5 0.0 5.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON96849.1 - 5.8e-07 30.1 0.0 1.5e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EON96849.1 - 1.2e-05 24.4 0.1 1.9e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 EON96849.1 - 0.00011 22.2 0.1 0.00018 21.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON96849.1 - 0.00014 21.8 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EON96849.1 - 0.00059 19.2 0.0 0.00082 18.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5_C PF17286.2 EON96849.1 - 0.0018 18.2 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_12 PF08242.12 EON96849.1 - 0.002 18.9 0.0 0.0033 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EON96849.1 - 0.006 16.1 0.1 0.0088 15.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.16 EON96849.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 EON96849.1 - 0.039 13.9 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EON96849.1 - 0.074 12.4 0.5 0.16 11.2 0.3 1.7 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.15 EON96849.1 - 0.14 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 HAT PF02184.16 EON96850.1 - 1.7e-30 104.6 61.8 3.8e-15 55.6 2.3 13.8 15 0 0 15 15 15 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EON96850.1 - 8.1e-27 91.6 24.0 9.6e-05 22.9 0.3 11.8 7 3 6 13 13 13 6 Tetratricopeptide repeat TPR_19 PF14559.6 EON96850.1 - 4.4e-25 88.0 0.2 2.6e-07 31.1 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat Suf PF05843.14 EON96850.1 - 2.5e-16 60.5 19.9 0.011 15.8 2.7 7.0 3 1 2 5 5 5 4 Suppressor of forked protein (Suf) TPR_15 PF13429.6 EON96850.1 - 2.4e-10 40.1 10.1 0.15 11.2 0.1 6.3 2 1 3 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EON96850.1 - 6.4e-09 35.3 0.4 0.34 11.2 0.0 6.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EON96850.1 - 1.1e-07 31.9 0.7 0.29 11.3 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EON96850.1 - 2.6e-07 30.8 16.8 3.3 8.5 0.0 8.9 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 EON96850.1 - 3.5e-07 30.8 10.2 1.9 9.2 0.2 7.8 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 EON96850.1 - 1.9e-06 27.5 21.4 0.24 11.6 0.1 9.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 EON96850.1 - 3.8e-06 26.9 3.4 2.9 8.5 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EON96850.1 - 0.00042 19.9 0.0 7.8 6.3 0.0 4.0 4 0 0 4 4 4 1 TPR repeat TPR_12 PF13424.6 EON96850.1 - 0.0025 18.1 13.7 6.6 7.1 0.0 7.7 10 0 0 10 10 9 1 Tetratricopeptide repeat NRDE-2 PF08424.10 EON96850.1 - 0.0067 15.6 29.8 1 8.4 0.8 6.4 3 3 3 6 6 6 4 NRDE-2, necessary for RNA interference TPR_1 PF00515.28 EON96850.1 - 0.013 15.3 7.5 3.9 7.5 0.0 6.1 8 0 0 8 8 7 0 Tetratricopeptide repeat TAtT PF16811.5 EON96850.1 - 0.092 12.0 9.2 1.1 8.5 0.2 4.6 3 1 0 3 3 3 0 TRAP transporter T-component U3_assoc_6 PF08640.11 EON96850.1 - 0.21 11.7 28.5 0.64 10.1 0.7 7.9 7 2 2 9 9 9 0 U3 small nucleolar RNA-associated protein 6 Fis1_TPR_C PF14853.6 EON96850.1 - 0.68 10.1 10.7 36 4.5 0.0 5.9 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Oxysterol_BP PF01237.18 EON96851.1 - 1.2e-77 261.3 0.0 4.7e-75 252.8 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein RNB PF00773.19 EON96852.1 - 6.8e-45 153.8 0.0 2.3e-29 102.8 0.0 2.8 3 0 0 3 3 3 2 RNB domain HrcA PF01628.21 EON96852.1 - 0.04 13.8 0.0 5 7.0 0.0 2.2 1 1 0 2 2 2 0 HrcA protein C terminal domain Retrotran_gag_2 PF14223.6 EON96852.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Fer2_3 PF13085.6 EON96853.1 - 1.9e-33 114.7 0.0 3.1e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EON96853.1 - 1.4e-08 35.1 6.1 1.4e-08 35.1 6.1 2.3 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EON96853.1 - 7.8e-08 32.7 7.9 7.8e-08 32.7 7.9 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EON96853.1 - 2.1e-07 30.9 3.0 2.1e-07 30.9 3.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EON96853.1 - 0.0021 17.9 2.7 0.0032 17.4 0.3 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 EON96853.1 - 0.0051 17.4 5.1 0.0051 17.4 5.1 2.5 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 EON96853.1 - 0.021 15.0 0.3 0.66 10.2 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.8 EON96853.1 - 0.1 13.2 0.9 0.1 13.2 0.9 2.1 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_9 PF13187.6 EON96853.1 - 0.52 10.5 11.2 3.1 8.1 9.3 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain Cyclin_N PF00134.23 EON96854.1 - 9.4e-11 41.6 0.5 2.8e-10 40.0 0.2 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EON96854.1 - 0.0042 17.2 0.0 0.073 13.2 0.0 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain U62_UL91 PF17442.2 EON96854.1 - 0.1 12.6 0.2 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Functional domain of U62 and UL91 proteins TFIIB PF00382.19 EON96854.1 - 0.12 12.4 0.1 0.46 10.6 0.1 1.9 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Nup84_Nup100 PF04121.13 EON96855.1 - 8.7e-190 632.4 0.1 1.1e-189 632.1 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Phage_TAC_2 PF06894.11 EON96855.1 - 0.039 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G TMF_TATA_bd PF12325.8 EON96856.1 - 0.0037 17.5 4.0 0.0037 17.5 4.0 8.5 5 3 3 8 8 8 3 TATA element modulatory factor 1 TATA binding DUF2521 PF10730.9 EON96856.1 - 0.02 14.9 0.2 0.18 11.8 0.2 2.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) tRNA-synt_1_2 PF13603.6 EON96856.1 - 0.086 12.3 0.0 0.26 10.8 0.0 1.8 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Filament PF00038.21 EON96856.1 - 3 7.3 88.6 2.2 7.8 2.6 7.0 3 1 3 6 6 6 0 Intermediate filament protein Myb_DNA-bind_6 PF13921.6 EON96857.1 - 9.5e-05 22.6 0.3 0.00017 21.8 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EON96857.1 - 0.053 13.7 1.4 0.1 12.8 1.4 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Rap1_C PF11626.8 EON96857.1 - 0.23 11.6 1.6 0.18 11.9 0.2 1.7 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-GRF PF06839.12 EON96858.1 - 1.1e-07 31.9 3.9 1.8e-07 31.2 3.9 1.4 1 0 0 1 1 1 1 GRF zinc finger Csm1_N PF18504.1 EON96858.1 - 0.026 14.9 0.5 0.064 13.6 0.5 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF995 PF06191.12 EON96858.1 - 0.64 9.7 3.0 0.5 10.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF995) SIR2 PF02146.17 EON96859.1 - 1.1e-25 90.6 0.0 3.7e-25 88.9 0.0 1.8 1 1 0 1 1 1 1 Sir2 family Med3 PF11593.8 EON96859.1 - 0.24 10.6 10.1 0.37 9.9 10.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sugar_tr PF00083.24 EON96860.1 - 1.6e-31 109.7 27.7 4.6e-18 65.3 8.6 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EON96860.1 - 2.8e-22 79.1 19.3 1.1e-13 50.9 11.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 EON96860.1 - 5.4 6.6 10.8 5.4 6.6 2.6 3.5 4 1 1 5 5 5 0 Domain of unknown function (DUF4131) Nop14 PF04147.12 EON96861.1 - 0.11 10.7 13.5 0.18 10.0 13.5 1.3 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EON96861.1 - 0.25 9.4 10.8 0.37 8.9 10.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Importin_rep_6 PF18829.1 EON96861.1 - 0.81 9.8 5.0 1.5 9.0 5.0 1.4 1 0 0 1 1 1 0 Importin repeat 6 RXT2_N PF08595.11 EON96861.1 - 0.86 9.6 10.9 0.12 12.4 5.5 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Peptidase_S64 PF08192.11 EON96861.1 - 2.9 6.3 7.2 4.5 5.7 7.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 PTPRCAP PF15713.5 EON96861.1 - 4.9 7.4 14.6 1.4 9.2 7.7 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated PTPA PF03095.15 EON96862.1 - 2.3e-114 381.9 0.0 2.6e-114 381.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein WD40 PF00400.32 EON96863.1 - 1.9e-17 63.3 7.1 0.0021 18.8 0.1 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON96863.1 - 2.4e-15 56.6 0.1 0.0063 16.8 0.0 5.8 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EON96863.1 - 2.8e-05 24.1 0.2 0.2 11.5 0.1 3.2 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.11 EON96863.1 - 0.0094 15.1 0.0 0.79 8.7 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1513) Coatomer_WDAD PF04053.14 EON96863.1 - 0.013 14.6 0.0 0.028 13.5 0.0 1.6 1 1 0 1 1 1 0 Coatomer WD associated region WD40_like PF17005.5 EON96863.1 - 0.023 14.0 0.0 0.2 10.9 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain Nup160 PF11715.8 EON96863.1 - 0.04 12.6 0.3 0.15 10.7 0.1 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 ELYS-bb PF16687.5 EON96863.1 - 0.12 11.0 0.0 0.27 9.8 0.0 1.5 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin Cytochrom_D1 PF02239.16 EON96863.1 - 0.13 10.8 0.0 11 4.5 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain SLS PF14611.6 EON96864.1 - 0.034 14.0 0.1 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator RPN5_C PF18098.1 EON96864.1 - 0.11 12.7 0.2 3.2 7.9 0.0 3.0 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN5 C-terminal domain AAA_lid_1 PF17857.1 EON96865.1 - 0.21 11.9 0.0 23 5.3 0.0 2.2 1 1 1 2 2 2 0 AAA+ lid domain Mod_r PF07200.13 EON96866.1 - 7.9e-37 126.6 3.5 9.3e-37 126.4 3.5 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein ERCC4 PF02732.15 EON96867.1 - 1e-24 87.5 0.0 1.8e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain Phage_holin_6_1 PF09682.10 EON96867.1 - 0.12 12.8 1.0 3.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) SH3_9 PF14604.6 EON96868.1 - 5.6e-28 96.5 4.1 3.6e-13 49.1 0.4 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EON96868.1 - 2.8e-27 94.1 6.9 1e-13 50.6 0.6 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EON96868.1 - 3.2e-17 61.9 0.0 1.6e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 EON96868.1 - 1.5e-15 57.1 0.0 4.1e-15 55.6 0.0 1.7 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein Ferritin_2 PF13668.6 EON96869.1 - 2.4e-27 95.8 4.1 3.5e-24 85.6 1.2 2.7 3 0 0 3 3 3 2 Ferritin-like domain Pkinase PF00069.25 EON96870.1 - 7.8e-69 232.0 0.0 9.9e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON96870.1 - 2.2e-31 109.1 0.0 3e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EON96870.1 - 3.9e-14 53.1 1.0 1.1e-13 51.7 1.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EON96870.1 - 1.3e-09 37.8 0.0 5.8e-09 35.7 0.0 1.8 1 1 0 2 2 2 1 Kinase-like C2 PF00168.30 EON96870.1 - 1.4e-08 34.9 0.0 3.5e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 EON96870.1 - 0.00075 18.5 0.5 0.0022 17.0 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Adeno_E3_15_3 PF03307.14 EON96870.1 - 0.0035 17.3 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 Adenovirus 15.3kD protein in E3 region Kdo PF06293.14 EON96870.1 - 0.0061 15.9 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EON96870.1 - 0.02 14.5 0.6 2.9 7.5 0.0 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EON96870.1 - 0.031 13.8 0.2 0.054 13.1 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EON96870.1 - 0.05 13.5 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fe_hyd_lg_C PF02906.14 EON96871.1 - 5.5e-11 42.6 0.0 7.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Sec10 PF07393.11 EON96872.1 - 4.7e-224 745.9 1.6 6.4e-224 745.5 1.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Baculo_PEP_C PF04513.12 EON96872.1 - 8.2 6.5 7.5 2.4 8.2 1.6 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus LAM_C PF12544.8 EON96873.1 - 0.00026 21.2 0.1 0.00061 20.0 0.1 1.6 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.21 EON96873.1 - 0.0021 18.4 0.0 0.0057 17.0 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily AltA1 PF16541.5 EON96874.1 - 0.0026 18.6 4.1 0.0051 17.7 3.8 1.5 1 1 0 1 1 1 1 Alternaria alternata allergen 1 TLV_coat PF00429.19 EON96874.1 - 0.012 14.3 3.2 0.013 14.2 3.2 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Pkinase PF00069.25 EON96875.1 - 9.1e-68 228.5 0.0 1.9e-67 227.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON96875.1 - 2.4e-37 128.7 0.0 4e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EON96875.1 - 0.00031 20.2 0.0 0.00065 19.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EON96875.1 - 0.0014 17.5 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EON96875.1 - 0.0019 18.1 0.0 0.0059 16.6 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EON96875.1 - 0.011 15.1 0.5 0.08 12.3 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EON96875.1 - 0.089 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 6PGD PF00393.19 EON96877.1 - 1.5e-126 421.6 0.0 1.9e-126 421.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EON96877.1 - 6.1e-50 169.5 0.0 9.5e-50 168.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EON96877.1 - 0.082 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 EON96877.1 - 0.12 12.6 0.0 0.36 11.1 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PGK PF00162.19 EON96877.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase C2 PF00168.30 EON96879.1 - 2.4e-84 278.3 0.1 1.1e-21 77.1 0.0 5.5 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 EON96879.1 - 2.2e-05 24.0 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain MLVIN_C PF18697.1 EON96879.1 - 0.11 12.6 0.1 1.9 8.7 0.0 2.6 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain TUG-UBL1 PF11470.8 EON96880.1 - 3.7e-26 91.1 0.2 9.5e-26 89.8 0.0 1.8 2 0 0 2 2 2 1 TUG ubiquitin-like domain RBD PF02196.15 EON96880.1 - 0.056 13.5 0.2 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Raf-like Ras-binding domain WD40 PF00400.32 EON96884.1 - 4e-39 131.9 21.9 2.2e-08 34.6 1.5 7.8 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON96884.1 - 3.3e-16 59.4 1.3 0.031 14.6 0.0 6.2 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 EON96884.1 - 6.5e-15 54.4 1.4 1.6e-14 53.2 1.4 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 EON96884.1 - 0.026 13.5 0.0 38 3.1 0.0 4.0 2 1 3 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EON96884.1 - 0.059 12.7 0.0 26 4.0 0.0 3.4 4 0 0 4 4 4 0 WD40-like domain Nbas_N PF15492.6 EON96884.1 - 0.08 12.3 0.1 18 4.5 0.0 2.6 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 EON96884.1 - 0.18 10.5 0.2 14 4.3 0.0 2.2 1 1 0 2 2 2 0 Nup133 N terminal like cwf18 PF08315.12 EON96884.1 - 0.25 12.0 1.7 0.41 11.3 1.7 1.3 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor NPR3 PF03666.13 EON96886.1 - 1.9e-146 488.5 0.0 1.9e-146 488.5 0.0 2.1 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 ER_lumen_recept PF00810.18 EON96888.1 - 0.019 15.8 0.9 0.034 15.0 0.9 1.5 1 1 0 1 1 1 0 ER lumen protein retaining receptor Med16 PF11635.8 EON96889.1 - 5.9e-30 103.9 0.1 7.9e-30 103.5 0.1 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 Gemini_AL1_M PF08283.11 EON96890.1 - 0.032 14.3 0.1 0.072 13.2 0.1 1.5 1 0 0 1 1 1 0 Geminivirus rep protein central domain LSM PF01423.22 EON96891.1 - 1e-20 73.2 0.1 1.1e-20 73.0 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EON96891.1 - 8.5e-05 22.6 0.1 0.0001 22.4 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EON96891.1 - 0.00034 20.7 0.2 0.0004 20.4 0.2 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain Hfq PF17209.3 EON96891.1 - 0.095 12.4 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Hfq protein CHCH PF06747.13 EON96893.1 - 1.7e-05 24.8 2.5 2.4e-05 24.3 2.5 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 EON96893.1 - 0.0022 18.3 2.7 0.025 14.9 3.1 1.9 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 EON96893.1 - 0.0036 17.6 4.3 0.14 12.6 0.8 2.1 1 1 1 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) TAFII55_N PF04658.13 EON96894.1 - 2.1e-49 167.3 0.4 4e-49 166.4 0.4 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region PCNA_N PF00705.18 EON96895.1 - 4.8e-58 194.4 4.2 5.8e-58 194.1 3.4 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EON96895.1 - 2.6e-49 166.6 0.0 7.3e-49 165.2 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 EON96895.1 - 5.1e-09 35.9 0.1 6.3e-09 35.6 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 EON96895.1 - 1.1e-06 27.9 0.5 4.1e-05 22.8 0.5 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 EON96895.1 - 0.00012 21.3 0.1 0.00032 19.9 0.1 1.8 1 1 0 1 1 1 1 Hus1-like protein Cmc1 PF08583.10 EON96896.1 - 8.4e-18 64.2 4.4 9.7e-18 64.0 4.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 EON96896.1 - 0.39 10.8 3.3 7.4 6.7 0.1 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, HATPase_c_3 PF13589.6 EON96897.1 - 4e-11 42.9 0.0 7e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 EON96897.1 - 6.4e-08 32.3 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 EON96897.1 - 2.1e-05 25.0 0.0 3.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pro_isomerase PF00160.21 EON96898.1 - 6.2e-51 172.8 0.1 1.4e-50 171.7 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EON96898.1 - 1.7e-08 34.9 0.0 0.00036 21.3 0.0 4.8 4 1 1 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON96898.1 - 0.0052 17.0 0.0 0.17 12.2 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EON96898.1 - 0.019 13.9 0.2 0.073 12.0 0.1 1.9 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DAHP_synth_1 PF00793.20 EON96899.1 - 5.1e-100 333.9 0.0 6.3e-100 333.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family SRP-alpha_N PF04086.13 EON96900.1 - 2 8.3 6.5 2.2 8.1 6.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RRN3 PF05327.11 EON96901.1 - 1.1e-174 582.1 0.0 1.1e-174 582.1 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 IBN_N PF03810.19 EON96901.1 - 0.06 13.3 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Importin-beta N-terminal domain zf-CCCH PF00642.24 EON96902.1 - 2.9e-08 33.4 20.0 3e-07 30.2 2.5 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EON96902.1 - 0.0058 16.7 3.3 0.0058 16.7 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain RRM_1 PF00076.22 EON96902.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 EON96902.1 - 0.022 15.5 3.9 0.48 11.1 0.2 2.4 2 0 0 2 2 2 0 Torus domain SCRG1 PF15224.6 EON96902.1 - 0.095 12.8 3.6 0.11 12.6 0.1 2.3 2 0 0 2 2 2 0 Scrapie-responsive protein 1 zf-CCCH_3 PF15663.5 EON96902.1 - 0.12 12.6 4.4 0.19 11.9 1.0 2.3 2 0 0 2 2 2 0 Zinc-finger containing family CBFD_NFYB_HMF PF00808.23 EON96903.1 - 4.6e-26 90.9 1.4 8.5e-26 90.0 1.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EON96903.1 - 7.7e-07 29.5 0.2 1.8e-06 28.3 0.2 1.7 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 EON96903.1 - 0.0016 18.4 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EON96903.1 - 0.0025 17.8 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 EON96903.1 - 0.021 14.9 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 EON96903.1 - 0.089 13.3 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A SIKE PF05769.11 EON96903.1 - 0.097 12.6 0.1 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 SIKE family MFS_1 PF07690.16 EON96906.1 - 2.4e-20 72.8 47.4 3.2e-20 72.4 46.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Phos_pyr_kin PF08543.12 EON96907.1 - 2.1e-12 47.0 0.0 3.3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EON96907.1 - 2.1e-07 30.6 0.2 6.8e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 pfkB family carbohydrate kinase HobA PF12163.8 EON96907.1 - 0.009 15.6 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 DNA replication regulator LIM PF00412.22 EON96908.1 - 8.9e-22 77.1 29.4 2.3e-08 34.2 5.7 3.6 4 0 0 4 4 4 3 LIM domain DUF2321 PF10083.9 EON96908.1 - 0.028 14.0 0.3 0.028 14.0 0.3 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-dskA_traR PF01258.17 EON96908.1 - 0.078 12.9 0.3 0.078 12.9 0.3 4.8 6 0 0 6 6 6 0 Prokaryotic dksA/traR C4-type zinc finger DZR PF12773.7 EON96908.1 - 9 6.4 29.6 13 5.9 9.4 4.5 1 1 2 3 3 3 0 Double zinc ribbon DNA_pol_B_palm PF14792.6 EON96909.1 - 9.7e-36 122.4 0.0 1.7e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EON96909.1 - 6.1e-24 84.0 0.2 2.5e-23 82.0 0.2 2.1 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EON96909.1 - 2.3e-19 68.9 0.2 5.3e-19 67.8 0.2 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 EON96909.1 - 6.5e-18 64.9 0.1 4.1e-17 62.3 0.1 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 EON96909.1 - 0.012 16.0 0.0 0.028 14.8 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain NTP_transf_2 PF01909.23 EON96909.1 - 0.014 15.7 0.1 0.032 14.5 0.1 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain Methyltransf_11 PF08241.12 EON96910.1 - 4.2e-12 46.5 0.0 8.4e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON96910.1 - 1.6e-11 44.7 0.0 3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON96910.1 - 0.00039 20.3 0.0 0.00052 19.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON96910.1 - 0.00041 21.0 0.0 0.0014 19.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 EON96910.1 - 0.002 17.6 0.0 0.063 12.8 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase NodS PF05401.11 EON96910.1 - 0.0021 17.7 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.20 EON96910.1 - 0.0037 16.4 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 EON96910.1 - 0.009 15.8 0.0 0.016 15.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON96910.1 - 0.016 14.5 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 EON96910.1 - 0.068 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) RNA_pol_Rpb4 PF03874.16 EON96911.1 - 9.7e-17 61.4 6.6 5.1e-16 59.1 6.6 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb4 ZnuA PF01297.17 EON96911.1 - 0.11 11.9 1.1 0.14 11.6 1.1 1.1 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Fungal_trans_2 PF11951.8 EON96912.1 - 2.6e-49 168.1 4.8 3.9e-41 141.1 0.3 2.0 1 1 1 2 2 2 2 Fungal specific transcription factor domain Dus PF01207.17 EON96914.1 - 4.3e-26 91.8 0.0 8.6e-26 90.7 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Sel1 PF08238.12 EON96915.1 - 1.5e-41 139.9 29.6 5.4e-06 26.9 0.1 7.5 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 EON96915.1 - 0.012 16.2 3.4 2.8 8.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EON96915.1 - 0.056 13.7 0.1 0.65 10.3 0.0 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DMRL_synthase PF00885.19 EON96916.1 - 6e-56 188.2 0.0 7.6e-56 187.9 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase HLH PF00010.26 EON96917.1 - 5.3e-13 48.7 0.0 3.7e-12 46.0 0.0 2.2 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3734 PF12536.8 EON96917.1 - 0.03 14.6 1.0 5.2 7.5 0.3 2.4 2 0 0 2 2 2 0 Patatin phospholipase Trs65 PF12735.7 EON96918.1 - 3.4e-132 440.7 0.0 4.2e-132 440.4 0.0 1.1 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Glutaredoxin PF00462.24 EON96919.1 - 6.7e-19 67.9 0.0 4.3e-17 62.1 0.0 2.6 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EON96919.1 - 3.9e-14 52.5 0.1 1.4e-13 50.7 0.0 1.9 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 EON96919.1 - 0.0054 17.0 0.0 4.7 7.6 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_3 PF13192.6 EON96919.1 - 0.0078 16.2 0.0 0.19 11.8 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin domain Disulph_isomer PF06491.11 EON96919.1 - 0.026 14.7 0.0 5.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Disulphide isomerase HyaE PF07449.11 EON96919.1 - 0.072 13.1 0.0 0.8 9.7 0.0 2.2 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE AMP-binding PF00501.28 EON96920.1 - 2.3e-94 316.4 0.0 3.8e-94 315.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON96920.1 - 3.2e-15 56.9 0.6 7.5e-15 55.7 0.6 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FF PF01846.19 EON96921.1 - 2.3e-52 175.0 11.6 4.1e-15 55.7 0.1 7.1 6 1 0 6 6 6 5 FF domain WW PF00397.26 EON96921.1 - 4.4e-18 65.1 16.1 6.2e-10 39.0 2.1 2.6 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 EON96921.1 - 0.021 15.5 10.7 1.3 9.7 0.1 4.8 6 0 0 6 6 6 0 p190-A and -B Rho GAPs FF domain Nrf1_DNA-bind PF10491.9 EON96921.1 - 0.048 13.3 0.6 0.19 11.4 0.2 2.1 2 0 0 2 2 2 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 VPS53_C PF16854.5 EON96921.1 - 0.096 12.6 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus Glyco_hyd_101C PF17451.2 EON96921.1 - 0.54 10.5 8.2 3.2 8.0 0.3 2.8 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Vezatin PF12632.7 EON96922.1 - 1.4e-76 257.6 0.0 2.3e-76 256.9 0.0 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF4203 PF13886.6 EON96922.1 - 0.032 13.9 1.4 0.051 13.3 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) UCR_14kD PF02271.16 EON96922.1 - 0.062 13.3 0.6 1.1 9.2 0.0 2.7 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex 14kD subunit T5orf172 PF10544.9 EON96924.1 - 0.11 13.0 0.6 0.19 12.3 0.6 1.4 1 0 0 1 1 1 0 T5orf172 domain Ammonium_transp PF00909.21 EON96925.1 - 3.9e-117 391.3 30.3 4.5e-117 391.1 30.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Proteasome PF00227.26 EON96926.1 - 5.4e-28 97.8 0.2 1.7e-27 96.2 0.4 1.7 2 1 0 2 2 2 1 Proteasome subunit Rad60-SLD PF11976.8 EON96927.1 - 2.2e-18 65.8 0.1 2.8e-18 65.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EON96927.1 - 8.5e-12 44.7 0.1 1e-11 44.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family SNF2_N PF00176.23 EON96928.1 - 4.4e-56 190.1 0.0 7.3e-56 189.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 EON96928.1 - 9.1e-26 89.5 3.7 1.3e-16 60.3 0.4 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 EON96928.1 - 7.6e-20 71.3 0.1 2.4e-19 69.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 EON96928.1 - 9e-15 54.9 0.4 5.6e-14 52.4 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) HDA2-3 PF11496.8 EON96928.1 - 1.1e-07 31.3 0.1 4e-07 29.5 0.1 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EON96928.1 - 2.1e-06 27.8 0.0 9e-06 25.8 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 EON96928.1 - 0.0005 20.4 0.1 0.0005 20.4 0.1 6.5 6 2 2 8 8 8 2 Chromodomain helicase DNA-binding domain 1 CHDCT2 PF08074.11 EON96928.1 - 0.032 14.4 0.3 0.23 11.6 0.0 2.6 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain SLIDE PF09111.10 EON96928.1 - 0.29 11.2 0.0 0.29 11.2 0.0 3.6 4 0 0 4 4 4 0 SLIDE YTH PF04146.15 EON96929.1 - 3.4e-63 212.5 0.0 5.6e-63 211.8 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 EON96929.1 - 0.042 13.7 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop PF01798.18 EON96930.1 - 3.3e-72 242.7 0.0 4.9e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EON96930.1 - 4.5e-44 150.2 1.7 1.2e-43 148.9 1.7 1.8 1 0 0 1 1 1 1 Prp31 C terminal domain Glyco_hydro_18 PF00704.28 EON96931.1 - 2.7e-77 260.6 5.9 3.1e-77 260.4 5.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PI3_PI4_kinase PF00454.27 EON96933.1 - 6e-39 134.3 0.1 1.2e-36 126.8 0.1 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EON96933.1 - 3.6e-23 81.9 0.1 9.9e-23 80.5 0.1 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Acetate_kinase PF00871.17 EON96934.1 - 1.9e-88 296.8 0.0 2.3e-88 296.5 0.0 1.1 1 0 0 1 1 1 1 Acetokinase family APS_kinase PF01583.20 EON96935.1 - 1.8e-72 242.4 0.0 2.9e-72 241.7 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EON96935.1 - 9.1e-06 25.9 0.0 1.8e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EON96935.1 - 0.00013 22.5 0.0 0.00019 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EON96935.1 - 0.00087 18.8 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 EON96935.1 - 0.019 15.4 0.0 0.027 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 EON96935.1 - 0.088 12.5 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 EON96935.1 - 0.093 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain 6PF2K PF01591.18 EON96935.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase G-alpha PF00503.20 EON96935.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit DUF463 PF04317.12 EON96935.1 - 0.17 10.7 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 BTB PF00651.31 EON96936.1 - 1.2e-09 38.3 0.1 1.5e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 BTB/POZ domain dUTPase PF00692.19 EON96937.1 - 6e-46 155.3 0.0 6.8e-46 155.1 0.0 1.0 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 EON96937.1 - 0.015 14.1 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) 14-3-3 PF00244.20 EON96938.1 - 2.3e-107 357.6 1.9 2.7e-107 357.3 1.9 1.0 1 0 0 1 1 1 1 14-3-3 protein MdcE PF06833.11 EON96939.1 - 0.065 12.7 0.4 0.09 12.3 0.4 1.2 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) DUF4395 PF14340.6 EON96939.1 - 0.22 11.9 5.0 0.075 13.4 1.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4395) DUF4149 PF13664.6 EON96939.1 - 1.1 9.7 7.0 0.2 12.0 2.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) DUF2415 PF10313.9 EON96940.1 - 0.0015 18.4 0.0 0.0037 17.1 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 EON96940.1 - 0.023 15.5 0.3 0.17 12.8 0.4 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Fungal_trans PF04082.18 EON96941.1 - 4.1e-15 55.5 0.2 6e-15 55.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Patatin PF01734.22 EON96942.1 - 4.5e-09 36.8 0.0 8.2e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase GPI-anchored PF10342.9 EON96943.1 - 6.5e-16 58.9 0.8 6.5e-16 58.9 0.8 2.8 2 1 0 2 2 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 EON96943.1 - 0.22 10.7 24.2 0.25 10.5 24.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein SAPS PF04499.15 EON96943.1 - 0.5 9.1 3.0 0.53 9.0 3.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GREB1 PF15782.5 EON96943.1 - 0.75 6.8 10.1 0.77 6.8 10.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Menin PF05053.13 EON96943.1 - 0.8 8.0 8.6 0.97 7.7 8.6 1.1 1 0 0 1 1 1 0 Menin Plasmodium_Vir PF05795.11 EON96943.1 - 1.4 8.3 9.0 1.6 8.1 9.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF572 PF04502.13 EON96943.1 - 1.8 8.1 6.3 2.3 7.7 6.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Lin-8 PF03353.15 EON96943.1 - 2.2 7.8 6.2 2.9 7.3 6.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 EON96943.1 - 3.3 6.2 19.5 4 5.9 19.5 1.1 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 EON96943.1 - 7.8 4.6 23.9 9.1 4.4 23.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Apt1 PF10351.9 EON96943.1 - 8.1 5.2 20.0 9.9 4.9 20.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PGM_PMM_I PF02878.16 EON96944.1 - 2.4e-18 66.2 0.3 5.8e-08 32.5 0.1 2.8 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EON96944.1 - 7.5e-12 45.3 0.4 3e-11 43.3 0.4 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 EON96944.1 - 0.00067 19.8 0.1 0.0072 16.5 0.1 2.6 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EON96944.1 - 0.023 15.3 0.6 1.5 9.4 0.4 3.6 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF1484 PF07363.11 EON96944.1 - 0.16 13.0 0.1 0.37 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) HTH_31 PF13560.6 EON96944.1 - 0.49 10.8 1.9 0.84 10.0 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain Chitin_synth_2 PF03142.15 EON96945.1 - 3.4e-294 976.3 0.4 5.5e-294 975.6 0.4 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EON96945.1 - 9.7e-13 48.5 7.8 9.7e-13 48.5 7.8 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EON96945.1 - 1.7e-11 44.4 0.2 2.7e-10 40.5 0.0 2.8 4 0 0 4 4 4 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EON96945.1 - 0.00048 19.7 0.0 0.025 14.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cyt-b5 PF00173.28 EON96945.1 - 0.00077 19.6 0.0 2.1 8.6 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 EON96945.1 - 0.03 14.1 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF3139 PF11337.8 EON96945.1 - 0.25 12.0 1.1 1.1 10.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Dus PF01207.17 EON96946.1 - 1.8e-42 145.5 0.0 7.2e-42 143.5 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Ligase_CoA PF00549.19 EON96947.1 - 4.2e-36 124.1 5.5 1.9e-19 70.0 0.4 2.4 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 EON96947.1 - 2.7e-13 50.4 0.3 8.8e-13 48.8 0.3 2.0 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 EON96947.1 - 2.1e-12 47.0 0.6 5.7e-09 35.9 0.1 2.4 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.10 EON96947.1 - 0.0008 19.0 0.0 0.0022 17.6 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain HTH_Tnp_ISL3 PF13542.6 EON96947.1 - 0.13 11.7 0.1 0.38 10.2 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 EON96947.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Kri1 PF05178.12 EON96948.1 - 0.98 10.0 8.3 19 5.9 7.1 2.7 2 1 0 2 2 2 0 KRI1-like family PGBA_C PF15437.6 EON96948.1 - 1 9.8 12.9 0.39 11.1 4.3 2.4 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal ELMO_CED12 PF04727.13 EON96949.1 - 9.7e-53 178.9 0.0 3.4e-52 177.1 0.0 1.8 2 0 0 2 2 2 1 ELMO/CED-12 family PH_12 PF16457.5 EON96949.1 - 7.2e-41 139.9 0.1 1.4e-40 139.0 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 EON96949.1 - 2.2e-14 53.7 0.0 4.8e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) peroxidase PF00141.23 EON96950.1 - 1.1e-47 162.7 0.0 2.5e-47 161.5 0.0 1.6 2 0 0 2 2 2 1 Peroxidase Xpo1 PF08389.12 EON96951.1 - 0.057 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Exportin 1-like protein Arginosuc_synth PF00764.19 EON96952.1 - 2.8e-144 481.2 0.0 3.5e-144 480.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase TRP PF06011.12 EON96953.1 - 4.5e-149 496.8 20.2 5.5e-149 496.5 20.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EON96953.1 - 7.2e-39 133.3 2.5 1.5e-38 132.3 2.5 1.6 1 0 0 1 1 1 1 ML-like domain Ribonuc_L-PSP PF01042.21 EON96954.1 - 8.7e-41 138.7 0.2 1.1e-40 138.4 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Exo_endo_phos PF03372.23 EON96955.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_hydro_63 PF03200.16 EON96956.1 - 3.2e-142 474.7 0.0 3.9e-142 474.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EON96956.1 - 2.6e-30 106.2 0.0 4.8e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain MFS_1 PF07690.16 EON96957.1 - 1e-10 41.1 45.4 2.2e-10 40.0 45.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2263 PF10021.9 EON96958.1 - 1.6e-18 67.5 0.0 3.9e-18 66.2 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 EON96958.1 - 0.1 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Macro domain Aldo_ket_red PF00248.21 EON96959.1 - 9.7e-45 153.0 0.0 1.1e-44 152.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DIOX_N PF14226.6 EON96961.1 - 6.5e-26 91.4 0.0 9.8e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EON96961.1 - 8.8e-20 71.1 0.0 1.6e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Clat_adaptor_s PF01217.20 EON96962.1 - 2.2e-41 141.1 0.0 5.3e-41 139.9 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Guanylate_kin PF00625.21 EON96963.1 - 0.13 12.0 3.3 0.29 10.8 3.3 1.6 1 0 0 1 1 1 0 Guanylate kinase tRNA-synt_1 PF00133.22 EON96964.1 - 9.1e-39 133.2 0.0 5.5e-27 94.3 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EON96964.1 - 1.2e-16 60.4 0.2 4.7e-10 38.8 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EON96964.1 - 1e-13 51.5 2.1 1.4e-13 51.0 1.3 1.7 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EON96964.1 - 5.4e-07 29.3 0.0 9.7e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain IpaB_EvcA PF03278.13 EON96964.1 - 0.0026 17.5 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 IpaB/EvcA family YxiJ PF14176.6 EON96964.1 - 0.054 14.0 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 YxiJ-like protein Transp_cyt_pur PF02133.15 EON96965.1 - 1.5e-23 83.3 9.9 2.9e-19 69.2 8.5 2.1 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Cyt-b5 PF00173.28 EON96966.1 - 6.6e-11 42.2 0.0 1.1e-10 41.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain OGFr_N PF04664.13 EON96966.1 - 0.095 12.2 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region adh_short_C2 PF13561.6 EON96967.1 - 1e-43 149.6 0.0 1.2e-43 149.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON96967.1 - 1.2e-43 148.8 0.0 1.5e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON96967.1 - 5e-10 39.6 0.1 7.2e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON96967.1 - 7.1e-05 22.4 0.0 0.00015 21.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EON96967.1 - 0.00026 20.9 0.0 0.0006 19.8 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EON96967.1 - 0.00033 20.1 0.0 0.00078 18.9 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Ldh_1_N PF00056.23 EON96967.1 - 0.015 15.4 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EON96967.1 - 0.034 13.3 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Aldo_ket_red PF00248.21 EON96968.1 - 8.1e-63 212.3 0.0 9.1e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cupredoxin_1 PF13473.6 EON96969.1 - 0.011 15.9 0.1 0.024 14.7 0.1 1.6 1 0 0 1 1 1 0 Cupredoxin-like domain Cu_bind_like PF02298.17 EON96969.1 - 0.029 14.4 0.2 0.061 13.3 0.2 1.6 1 1 0 1 1 1 0 Plastocyanin-like domain MGC-24 PF05283.11 EON96969.1 - 0.96 9.9 7.2 0.43 11.0 4.5 1.8 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ribosomal_S7 PF00177.21 EON96970.1 - 3.6e-37 127.3 1.5 4.7e-37 126.9 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Peptidase_M24 PF00557.24 EON96971.1 - 8.1e-19 68.1 0.0 1e-18 67.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 HSP70 PF00012.20 EON96972.1 - 1.2e-13 50.1 0.0 3.6e-11 42.0 0.0 2.4 2 1 1 3 3 3 2 Hsp70 protein NTP_transf_7 PF07984.12 EON96972.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase DUF2958 PF11171.8 EON96972.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) Peptidase_M22 PF00814.25 EON96972.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family Glyco_hydro_10 PF00331.20 EON96973.1 - 8.2e-86 288.0 0.0 9.4e-86 287.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 MFS_1 PF07690.16 EON96974.1 - 8.7e-14 51.2 19.9 8.7e-14 51.2 19.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily NmrA PF05368.13 EON96975.1 - 3.8e-36 124.8 0.0 4.9e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EON96975.1 - 1.7e-17 63.9 0.1 2.1e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EON96975.1 - 5.1e-07 29.4 0.0 2.4e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EON96975.1 - 8.5e-05 21.7 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EON96975.1 - 0.00098 18.6 0.1 0.0035 16.8 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EON96975.1 - 0.0019 18.1 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EON96975.1 - 0.006 16.0 0.0 0.0096 15.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EON96975.1 - 0.0069 15.6 0.0 0.033 13.4 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 EON96975.1 - 0.03 13.4 0.2 0.19 10.8 0.2 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 EON96975.1 - 0.077 13.1 0.1 0.2 11.8 0.1 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NADH-UOR_E PF16514.5 EON96975.1 - 0.15 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 putative NADH-ubiquinone oxidoreductase chain E MFS_1 PF07690.16 EON96976.1 - 2.8e-34 118.6 71.8 1.3e-26 93.4 33.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tubulin PF00091.25 EON96977.1 - 4.1e-67 226.2 0.0 6e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EON96977.1 - 1.2e-49 167.6 0.1 2e-49 166.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EON96977.1 - 0.0021 17.8 0.0 0.0054 16.4 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Ribosomal_S25 PF03297.15 EON96978.1 - 6.8e-39 132.1 4.0 7.4e-39 132.0 4.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein RNA_pol_Rpc34 PF05158.12 EON96978.1 - 0.03 13.7 0.2 0.048 13.1 0.1 1.3 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit HTH_24 PF13412.6 EON96978.1 - 0.034 13.7 0.1 0.053 13.1 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 EON96978.1 - 0.041 13.8 0.0 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.7 EON96978.1 - 0.05 13.5 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 MarR family EF-hand_4 PF12763.7 EON96979.1 - 1.4e-32 111.7 0.0 3.7e-12 46.1 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EON96979.1 - 2.4e-08 34.3 0.0 0.0018 18.7 0.1 4.4 4 0 0 4 4 4 1 EF-hand domain pair UBA PF00627.31 EON96979.1 - 1.9e-06 27.6 0.1 4.5e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 EON96979.1 - 1.2e-05 24.5 0.0 17 5.2 0.0 5.1 5 0 0 5 5 5 0 EF hand EF-hand_6 PF13405.6 EON96979.1 - 0.00015 21.4 0.2 3 8.0 0.0 4.3 5 0 0 5 5 4 1 EF-hand domain EF-hand_8 PF13833.6 EON96979.1 - 0.00087 19.1 0.0 1.6 8.7 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain pair Spc7 PF08317.11 EON96979.1 - 0.007 15.3 34.6 0.086 11.7 20.8 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein Macoilin PF09726.9 EON96979.1 - 0.0092 14.6 18.4 0.018 13.6 18.4 1.4 1 0 0 1 1 1 1 Macoilin family TMF_TATA_bd PF12325.8 EON96979.1 - 0.071 13.3 29.7 1.6 9.0 13.4 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 EON96979.1 - 0.079 12.3 34.6 0.44 9.9 12.2 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 EON96979.1 - 0.21 9.1 30.7 0.29 8.6 30.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 EON96979.1 - 0.41 10.7 15.5 0.036 14.1 6.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FUSC PF04632.12 EON96979.1 - 0.87 8.0 9.7 1.5 7.3 9.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-F_leu_zip PF10473.9 EON96979.1 - 0.92 9.5 33.8 0.072 13.1 15.9 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 EON96979.1 - 0.95 10.4 31.4 1 10.3 11.5 3.5 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Rab5-bind PF09311.11 EON96979.1 - 1.5 8.2 27.3 9.9 5.4 27.4 2.1 1 1 0 1 1 1 0 Rabaptin-like protein TolA_bind_tri PF16331.5 EON96979.1 - 2.6 8.2 34.5 0.3 11.2 8.4 4.5 1 1 3 4 4 4 0 TolA binding protein trimerisation Bap31_Bap29_C PF18035.1 EON96979.1 - 2.7 8.1 16.9 0.6 10.2 0.2 3.7 4 0 0 4 4 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain APG6_N PF17675.1 EON96979.1 - 2.8 8.5 38.7 32 5.0 15.9 3.3 1 1 1 2 2 1 0 Apg6 coiled-coil region SOGA PF11365.8 EON96979.1 - 3 9.1 16.4 4.7 8.4 1.1 3.4 2 1 1 3 3 3 0 Protein SOGA ADIP PF11559.8 EON96979.1 - 3.8 7.6 40.6 1.3 9.1 13.0 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.6 EON96979.1 - 3.9 6.0 22.5 5.9 5.4 22.5 1.2 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.12 EON96979.1 - 5 7.2 39.2 5.6 7.0 24.5 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 EON96979.1 - 5.9 6.1 35.7 1.4 8.2 12.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Golgin_A5 PF09787.9 EON96979.1 - 6.1 6.2 31.3 0.16 11.4 19.0 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 Frataxin_Cyay PF01491.16 EON96981.1 - 5.5e-38 129.4 0.0 6.9e-38 129.0 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain KASH_CCD PF14662.6 EON96982.1 - 0.0028 17.5 7.5 0.0079 16.0 7.5 1.8 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 EON96982.1 - 0.021 15.0 3.8 0.021 15.0 3.8 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 EON96982.1 - 0.026 14.8 9.0 0.21 12.0 0.5 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain WASH-7_C PF14746.6 EON96982.1 - 0.04 13.6 4.6 0.26 11.0 4.3 2.3 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal End3 PF12761.7 EON96982.1 - 0.049 13.8 8.8 0.096 12.8 8.8 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF4618 PF15397.6 EON96982.1 - 0.072 12.5 8.3 0.037 13.4 5.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) FapA PF03961.13 EON96982.1 - 0.34 9.5 4.2 0.6 8.7 4.2 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fez1 PF06818.15 EON96982.1 - 0.48 10.8 14.2 0.31 11.5 9.7 2.5 1 1 1 2 2 2 0 Fez1 LTXXQ PF07813.12 EON96982.1 - 0.8 10.5 9.3 0.055 14.2 2.8 2.3 2 0 0 2 2 2 0 LTXXQ motif family protein SlyX PF04102.12 EON96982.1 - 1.6 9.4 5.7 18 6.0 2.5 2.9 2 0 0 2 2 2 0 SlyX CENP-H PF05837.12 EON96982.1 - 3.1 8.2 9.1 4.8 7.6 0.2 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) FlaC_arch PF05377.11 EON96982.1 - 3.7 8.0 5.9 19 5.7 0.1 3.6 4 0 0 4 4 2 0 Flagella accessory protein C (FlaC) DUF1640 PF07798.11 EON96982.1 - 4.2 7.4 9.4 8.8 6.3 9.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF5595 PF18077.1 EON96982.1 - 6 7.0 7.1 1.9 8.6 3.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) DEAD PF00270.29 EON96983.1 - 1.3e-30 106.5 0.2 3e-14 53.2 0.1 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EON96983.1 - 6.2e-23 81.3 0.0 1.6e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON96983.1 - 0.00047 20.2 0.0 0.00047 20.2 0.0 2.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit CENP-X PF09415.10 EON96984.1 - 9.2e-26 90.0 0.1 1.9e-25 89.0 0.1 1.5 1 0 0 1 1 1 1 CENP-S associating Centromere protein X DUF688 PF05097.12 EON96984.1 - 0.058 12.6 0.5 0.067 12.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) PBP1_TM PF14812.6 EON96984.1 - 0.11 12.9 1.8 0.17 12.2 1.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CBFD_NFYB_HMF PF00808.23 EON96984.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Acetyltransf_1 PF00583.25 EON96987.1 - 1.2e-05 25.5 0.0 9.8e-05 22.6 0.0 2.4 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EON96987.1 - 0.0002 21.3 0.0 0.31 11.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EON96987.1 - 0.00041 20.7 0.0 0.0012 19.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 EON96987.1 - 0.0047 17.6 0.0 6.3 7.6 0.0 3.0 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain AstA PF04958.12 EON96987.1 - 0.19 10.3 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit DUF4246 PF14033.6 EON96988.1 - 9e-182 605.2 0.0 1.1e-181 605.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EON96988.1 - 0.029 14.8 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase IBR PF01485.21 EON96989.1 - 1.8e-13 50.5 6.8 1e-11 44.9 3.1 2.3 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain Zn-ribbon_8 PF09723.10 EON96989.1 - 0.66 10.1 4.8 9.1 6.5 0.1 2.9 2 1 0 2 2 2 0 Zinc ribbon domain Lar_restr_allev PF14354.6 EON96989.1 - 0.96 9.9 9.5 44 4.6 0.2 3.9 2 1 0 2 2 2 0 Restriction alleviation protein Lar Methyltransf_25 PF13649.6 EON96990.1 - 5.1e-09 36.7 0.0 1.5e-08 35.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON96990.1 - 7.9e-07 29.0 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EON96990.1 - 1e-06 28.7 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 EON96990.1 - 1.1e-05 25.9 0.0 3.2e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON96990.1 - 8.2e-05 22.5 0.0 0.00034 20.5 0.0 2.1 1 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON96990.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EON96990.1 - 0.00053 20.7 0.0 0.0014 19.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EON96990.1 - 0.00094 20.2 0.0 0.0033 18.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 EON96990.1 - 0.0015 17.7 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.17 EON96990.1 - 0.025 14.1 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.20 EON96990.1 - 0.042 13.1 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase NodS PF05401.11 EON96990.1 - 0.08 12.5 0.0 0.2 11.3 0.0 1.8 1 1 0 1 1 1 0 Nodulation protein S (NodS) Glyco_hydro_16 PF00722.21 EON96991.1 - 1.1e-06 28.3 0.6 1.6e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 PIGA PF08288.12 EON96992.1 - 6.5e-45 151.7 3.0 2.4e-44 149.9 1.0 2.4 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EON96992.1 - 5.7e-28 98.0 0.3 8.7e-28 97.4 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EON96992.1 - 3.7e-27 94.9 0.0 5.7e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EON96992.1 - 9e-23 81.2 0.1 1.9e-22 80.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EON96992.1 - 2.6e-12 47.5 0.0 4.8e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EON96992.1 - 0.00017 21.9 0.0 0.00089 19.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EON96992.1 - 0.00053 20.0 0.1 0.001 19.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Mito_carr PF00153.27 EON96993.1 - 2.2e-68 226.2 4.9 1.4e-24 85.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldo_ket_red PF00248.21 EON96994.1 - 1.4e-27 96.6 0.0 1.6e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PSDC PF12588.8 EON96995.1 - 1.2e-45 154.9 0.0 4.4e-45 153.1 0.0 1.8 1 1 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EON96995.1 - 4.7e-37 127.5 0.0 8.3e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 EON96995.1 - 0.0017 18.1 0.5 0.36 10.7 0.2 2.4 2 0 0 2 2 2 2 Biotin-lipoyl like PTS_EIIA_1 PF00358.20 EON96995.1 - 0.022 14.5 0.3 0.065 13.0 0.3 1.8 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Biotin_lipoyl PF00364.22 EON96995.1 - 0.056 13.3 0.0 2.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Biotin-requiring enzyme GFA PF04828.14 EON96996.1 - 4.8e-13 49.3 0.0 5.5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.16 EON96996.1 - 0.0049 16.7 0.1 0.0096 15.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit Auto_anti-p27 PF06677.12 EON96996.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) UNC-93 PF05978.16 EON96997.1 - 1.5e-07 31.3 3.7 4.5e-07 29.7 3.7 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 LAB_N PF07578.11 EON96997.1 - 0.0061 16.6 0.4 0.026 14.6 0.1 2.3 2 0 0 2 2 2 1 Lipid A Biosynthesis N-terminal domain DUF4013 PF13197.6 EON96997.1 - 0.015 15.2 2.4 0.015 15.2 2.4 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF4013) Peptidase_S15 PF02129.18 EON96998.1 - 2.9e-50 171.4 0.4 3.9e-50 170.9 0.4 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 EON96998.1 - 2.4e-42 145.4 0.0 4.5e-42 144.5 0.0 1.4 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 EON96998.1 - 1.4e-09 37.6 0.0 5.6e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EON96998.1 - 4.5e-09 36.3 0.1 2.2e-08 34.1 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EON96998.1 - 2.3e-07 30.5 0.4 1e-06 28.4 0.0 2.1 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EON96998.1 - 1.1e-06 29.4 0.6 2.5e-06 28.3 0.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EON96998.1 - 0.012 15.2 0.0 0.093 12.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Methyltransf_25 PF13649.6 EON96999.1 - 2.2e-13 50.7 0.0 6.8e-13 49.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON96999.1 - 2.3e-11 44.2 0.0 6.8e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EON96999.1 - 2.6e-11 43.4 0.0 5.3e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EON96999.1 - 3.3e-09 36.7 0.0 6.6e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EON96999.1 - 4.1e-07 30.0 0.1 7.8e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EON96999.1 - 1e-06 28.4 0.2 1.9e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EON96999.1 - 1.3e-06 28.4 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EON96999.1 - 1.8e-05 24.2 0.0 3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EON96999.1 - 9.1e-05 23.1 0.0 0.00028 21.6 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Met_10 PF02475.16 EON96999.1 - 0.00074 19.3 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 EON96999.1 - 0.0026 17.5 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EON96999.1 - 0.004 16.9 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_9 PF08003.11 EON96999.1 - 0.0046 15.9 0.0 0.0075 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 EON96999.1 - 0.0097 15.3 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_24 PF13578.6 EON96999.1 - 0.0097 16.9 0.0 0.034 15.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON96999.1 - 0.035 13.4 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 EON96999.1 - 0.091 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 EON96999.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_2 PF00891.18 EON96999.1 - 0.16 11.3 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain DUF4763 PF15960.5 EON96999.1 - 0.35 10.2 0.8 0.52 9.6 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) NAD_binding_8 PF13450.6 EON97000.1 - 1.8e-11 44.1 0.1 3e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EON97000.1 - 8.8e-09 35.2 0.0 5.9e-08 32.4 0.0 1.8 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 EON97000.1 - 0.0025 17.5 0.1 0.003 17.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON97000.1 - 0.0041 16.4 0.0 0.0053 16.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EON97000.1 - 0.014 14.7 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON97000.1 - 0.015 14.4 0.0 0.04 13.0 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 EON97000.1 - 0.017 15.1 0.0 0.066 13.2 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EON97000.1 - 0.12 11.0 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein zf-C2H2 PF00096.26 EON97001.1 - 1.1e-10 41.3 12.9 0.0056 17.1 1.3 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EON97001.1 - 2.6e-05 24.7 9.3 0.84 10.6 1.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 EON97001.1 - 5.6 7.3 6.9 2.3 8.6 1.3 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rav1p_C PF12234.8 EON97002.1 - 2.2e-135 452.6 3.8 9.9e-128 427.3 3.3 2.0 1 1 1 2 2 2 2 RAVE protein 1 C terminal DUF627 PF04781.12 EON97002.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) V-SNARE PF05008.15 EON97003.1 - 3.1e-24 85.2 0.6 3.1e-24 85.2 0.6 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EON97003.1 - 1.2e-17 63.9 3.1 1.2e-17 63.9 3.1 2.4 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus FAM76 PF16046.5 EON97003.1 - 0.16 11.3 0.6 0.21 10.9 0.0 1.5 2 0 0 2 2 2 0 FAM76 protein Exonuc_VII_L PF02601.15 EON97003.1 - 1.3 8.5 6.7 2.4 7.7 6.7 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit AA_permease PF00324.21 EON97004.1 - 1.4e-80 271.2 16.7 2.1e-80 270.6 16.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON97004.1 - 3.5e-22 78.8 23.4 4.2e-22 78.6 23.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF974 PF06159.13 EON97005.1 - 4.1e-82 275.7 0.0 5.8e-82 275.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) KH_1 PF00013.29 EON97005.1 - 1.3e-10 40.9 0.0 7.2e-08 32.1 0.0 2.5 2 0 0 2 2 2 2 KH domain MMR_HSR1 PF01926.23 EON97006.1 - 6.5e-05 23.0 0.0 0.64 10.1 0.0 2.8 3 0 0 3 3 3 2 50S ribosome-binding GTPase EPSP_synthase PF00275.20 EON97007.1 - 1.4e-128 429.2 0.0 2e-128 428.7 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EON97007.1 - 6.6e-102 340.1 0.0 9.9e-102 339.6 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EON97007.1 - 2.9e-57 194.6 0.0 4.7e-57 193.9 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EON97007.1 - 3.8e-35 121.4 0.0 3.1e-33 115.1 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EON97007.1 - 3.5e-25 88.0 0.0 8e-25 86.9 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 EON97007.1 - 2e-08 34.3 0.0 3.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 EON97007.1 - 0.00012 22.2 0.0 0.00058 19.9 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 EON97007.1 - 0.00016 21.4 0.3 0.00037 20.2 0.3 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain AAA_18 PF13238.6 EON97007.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EON97007.1 - 0.2 11.9 0.0 0.57 10.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3712 PF12505.8 EON97008.1 - 9.1e-08 32.4 0.3 1.1e-06 29.0 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 EON97008.1 - 0.0012 19.3 0.4 1.3 9.6 0.0 4.5 4 1 0 4 4 4 1 Late embryogenesis abundant protein ALS_ss_C PF10369.9 EON97009.1 - 1.7e-15 56.9 0.0 2.6e-14 53.2 0.0 2.5 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 EON97009.1 - 2.4e-15 56.0 0.1 4.4e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EON97009.1 - 1.6e-08 34.3 0.0 2.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 EON97009.1 - 0.081 12.9 0.0 21 5.2 0.0 2.5 2 0 0 2 2 2 0 ACT domain Uteroglobin PF01099.17 EON97010.1 - 0.0097 16.2 0.3 0.15 12.4 0.1 2.5 2 0 0 2 2 2 1 Uteroglobin family RVT_1 PF00078.27 EON97010.1 - 0.075 12.5 0.0 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) PPI_Ypi1 PF07491.11 EON97011.1 - 7.4e-23 80.2 6.6 4.1e-22 77.8 6.6 2.2 1 1 0 1 1 1 1 Protein phosphatase inhibitor AF-4 PF05110.13 EON97011.1 - 0.00045 18.5 4.4 0.00069 17.9 4.4 1.4 1 0 0 1 1 1 1 AF-4 proto-oncoprotein DENN PF02141.21 EON97012.1 - 8e-18 65.0 0.0 1.4e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EON97012.1 - 4.8e-14 52.8 0.0 9.1e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 uDENN domain OTCace PF00185.24 EON97013.1 - 3.8e-44 150.5 0.0 4.7e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EON97013.1 - 2.5e-10 40.6 0.0 4.2e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain XRN_M PF17846.1 EON97014.1 - 1.9e-138 462.2 0.1 9.8e-138 459.8 0.0 2.1 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 EON97014.1 - 3.4e-100 334.4 0.0 9.7e-100 333.0 0.0 1.8 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_2 PF13696.6 EON97014.1 - 0.065 13.1 1.7 0.14 12.0 1.7 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF726 PF05277.12 EON97015.1 - 9e-89 297.8 0.5 3.1e-67 227.0 0.1 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF726) PaaA_PaaC PF05138.12 EON97015.1 - 0.09 11.9 0.3 0.24 10.6 0.1 1.7 2 0 0 2 2 2 0 Phenylacetic acid catabolic protein NUC173 PF08161.12 EON97016.1 - 1.7e-81 272.8 0.0 9.2e-78 260.6 0.0 2.8 3 0 0 3 3 3 2 NUC173 domain DUF3384 PF11864.8 EON97016.1 - 0.036 13.0 0.1 0.47 9.3 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3384) CtaG_Cox11 PF04442.14 EON97017.1 - 1.1e-60 204.1 0.0 1.3e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 L51_S25_CI-B8 PF05047.16 EON97018.1 - 1.3e-20 73.0 0.0 2.3e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain GTP_CH_N PF12471.8 EON97018.1 - 0.038 13.7 0.1 0.043 13.6 0.1 1.1 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal Uso1_p115_head PF04869.14 EON97019.1 - 2.6e-119 398.0 0.0 5e-119 397.0 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EON97019.1 - 1.7e-20 73.6 23.5 1.7e-20 73.6 23.5 3.3 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Effector_1 PF04518.12 EON97019.1 - 6 5.9 17.3 0.12 11.4 6.5 2.4 1 1 1 2 2 2 0 Effector from type III secretion system NPV_P10 PF05531.12 EON97019.1 - 8.2 7.0 6.2 52 4.4 0.2 3.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.8 EON97020.1 - 0.024 13.9 20.3 0.22 10.8 15.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Herpes_UL6 PF01763.16 EON97020.1 - 0.19 10.2 4.3 0.33 9.4 4.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like Fib_alpha PF08702.10 EON97020.1 - 1.3 9.2 17.6 1.5 9.0 6.1 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Tweety PF04906.13 EON97020.1 - 1.5 7.4 3.2 2.3 6.8 3.2 1.1 1 0 0 1 1 1 0 Tweety FemAB PF02388.16 EON97020.1 - 3.2 6.5 8.4 5.1 5.8 8.4 1.3 1 0 0 1 1 1 0 FemAB family Asp-B-Hydro_N PF05279.11 EON97020.1 - 6.2 6.8 16.4 12 5.9 16.4 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF16 PF01519.16 EON97020.1 - 6.2 7.4 10.9 3.3 8.2 7.7 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 Arrestin_N PF00339.29 EON97021.1 - 1.4e-14 54.3 0.0 3.3e-10 40.2 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Vps62 PF06101.11 EON97022.1 - 2.9e-08 32.5 1.1 1.1e-07 30.6 0.4 1.9 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 DUF1302 PF06980.11 EON97022.1 - 0.15 10.6 0.1 0.24 10.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) Med19 PF10278.9 EON97023.1 - 4 7.4 7.5 1.2e+02 2.6 7.5 2.4 1 1 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Asp_protease_2 PF13650.6 EON97024.1 - 4e-05 24.2 0.0 6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EON97024.1 - 0.0011 19.5 0.0 0.0015 19.0 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Ribosomal_L7Ae PF01248.26 EON97025.1 - 6.6e-24 83.5 0.0 7.5e-24 83.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family UcrQ PF02939.16 EON97026.1 - 6e-37 125.4 1.1 7.2e-37 125.2 1.1 1.1 1 0 0 1 1 1 1 UcrQ family Vac7 PF12751.7 EON97027.1 - 6.6e-44 150.9 0.3 8.3e-44 150.6 0.3 1.1 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 zf-AN1 PF01428.16 EON97028.1 - 1e-11 44.8 8.6 1e-11 44.8 8.6 1.7 2 0 0 2 2 2 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 EON97028.1 - 0.23 11.8 4.8 0.44 10.9 4.8 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain RrnaAD PF00398.20 EON97029.1 - 6.5e-53 179.5 0.0 1.3e-52 178.5 0.0 1.4 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EON97029.1 - 1.2e-07 32.4 0.0 3e-07 31.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON97029.1 - 1e-05 26.1 0.0 2.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EON97029.1 - 0.00051 19.4 0.0 0.0008 18.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EON97029.1 - 0.00075 20.2 0.0 0.0033 18.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EON97029.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EON97029.1 - 0.012 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 EON97029.1 - 0.023 14.3 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 EON97029.1 - 0.032 14.0 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DREV PF05219.12 EON97029.1 - 0.068 12.3 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_23 PF13489.6 EON97029.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AAA_lid_4 PF17864.1 EON97029.1 - 0.076 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 RuvB AAA lid domain UPF0020 PF01170.18 EON97029.1 - 0.088 12.5 0.0 2.1 8.0 0.0 2.3 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 CHORD PF04968.12 EON97030.1 - 0.17 12.6 7.1 0.11 13.2 1.2 2.4 1 1 1 2 2 2 0 CHORD Band_7 PF01145.25 EON97031.1 - 7.5e-24 84.7 8.9 1.8e-23 83.5 8.9 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EON97031.1 - 0.00019 20.6 5.9 0.00026 20.2 5.9 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF3103 PF11301.8 EON97031.1 - 0.038 12.8 0.6 0.06 12.1 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3103) ADH_N PF08240.12 EON97032.1 - 4.5e-26 90.9 2.0 1.1e-25 89.6 2.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON97032.1 - 1.3e-19 70.5 0.3 2.6e-19 69.5 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EON97032.1 - 0.0011 18.4 0.4 0.0019 17.5 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 EON97032.1 - 0.003 17.1 0.1 0.0063 16.0 0.1 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EON97032.1 - 0.084 13.9 0.0 0.19 12.8 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Imm70 PF15601.6 EON97032.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 70 2-Hacid_dh_C PF02826.19 EON97032.1 - 0.19 11.1 0.1 0.3 10.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF676 PF05057.14 EON97033.1 - 5.8e-52 176.4 0.0 8.2e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EON97033.1 - 1.3e-05 26.0 0.4 7.3e-05 23.5 0.4 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EON97033.1 - 9.9e-05 22.3 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EON97033.1 - 0.022 14.5 0.1 0.096 12.4 0.1 1.9 1 1 0 1 1 1 0 PGAP1-like protein Lipase_2 PF01674.18 EON97033.1 - 0.095 12.2 0.0 0.16 11.5 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 2) Ribosomal_L16 PF00252.18 EON97034.1 - 1.6e-44 151.1 0.1 2e-44 150.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e HhH-GPD PF00730.25 EON97035.1 - 1.6e-17 63.9 0.0 2.6e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EON97035.1 - 3.6e-08 32.9 0.0 9.8e-08 31.5 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif APH PF01636.23 EON97036.1 - 3.6e-16 59.8 0.5 5.2e-16 59.3 0.1 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EON97036.1 - 0.00011 21.9 0.2 0.044 13.4 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.20 EON97036.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 EON97036.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase SH3_1 PF00018.28 EON97038.1 - 5.2e-14 51.6 0.1 1.1e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain BAR PF03114.18 EON97038.1 - 7.3e-12 45.4 0.4 9.7e-12 45.0 0.4 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 EON97038.1 - 9.5e-11 41.4 0.0 1.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EON97038.1 - 7.3e-10 38.4 0.0 1.4e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 EON97038.1 - 0.016 14.4 0.3 0.025 13.7 0.3 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Mito_fiss_reg PF05308.11 EON97038.1 - 0.02 15.0 0.3 0.03 14.4 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3104 PF11302.8 EON97038.1 - 0.066 13.0 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Pil1 PF13805.6 EON97038.1 - 0.068 12.6 1.5 0.1 12.0 1.5 1.2 1 0 0 1 1 1 0 Eisosome component PIL1 dCMP_cyt_deam_1 PF00383.23 EON97039.1 - 9.1e-22 76.8 0.0 2.9e-21 75.2 0.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EON97039.1 - 3e-17 62.6 0.1 2e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 EON97039.1 - 0.0087 16.1 4.7 0.038 14.1 0.0 3.1 4 0 0 4 4 4 1 Bd3614-like deaminase DUF5396 PF17374.2 EON97039.1 - 0.027 12.4 0.1 0.047 11.5 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5396) Macoilin PF09726.9 EON97039.1 - 2.7 6.4 5.3 4.4 5.7 5.3 1.3 1 0 0 1 1 1 0 Macoilin family DUF2052 PF09747.9 EON97042.1 - 4.4e-30 105.3 17.3 1.9e-15 57.5 1.7 2.1 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) MARVEL PF01284.23 EON97043.1 - 0.00013 22.0 17.5 0.00069 19.7 15.5 2.1 1 1 1 2 2 2 2 Membrane-associating domain VIT1 PF01988.19 EON97043.1 - 0.071 13.0 2.1 0.081 12.8 1.8 1.3 1 1 0 1 1 1 0 VIT family Acetyltransf_1 PF00583.25 EON97044.1 - 7.2e-12 45.6 0.1 9.2e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON97044.1 - 3.6e-08 33.7 0.5 5.5e-08 33.1 0.5 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EON97044.1 - 8.5e-08 32.2 0.1 1.1e-07 31.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ferredoxin_N PF16947.5 EON97044.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of 4Fe-4S ferredoxin iron-sulfur binding adh_short_C2 PF13561.6 EON97045.1 - 6.1e-27 94.7 0.0 6.9e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON97045.1 - 2.8e-20 72.6 0.1 3.2e-20 72.4 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase HypA PF01155.19 EON97047.1 - 0.12 12.4 0.7 0.27 11.3 0.7 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Serglycin PF04360.12 EON97047.1 - 0.13 12.2 0.9 0.23 11.4 0.9 1.4 1 0 0 1 1 1 0 Serglycin Zn_ribbon_SprT PF17283.2 EON97047.1 - 8.4 6.4 7.0 72 3.4 3.4 3.4 2 1 0 2 2 2 0 SprT-like zinc ribbon domain GFA PF04828.14 EON97048.1 - 5.1e-08 33.1 2.6 8e-07 29.3 0.1 2.6 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF1100 PF06500.11 EON97049.1 - 4.1e-07 29.1 0.0 5.9e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Esterase PF00756.20 EON97049.1 - 0.0038 16.9 0.0 0.031 13.9 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 EON97049.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EON97049.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family UBX PF00789.20 EON97050.1 - 8.1e-10 38.8 0.0 1.9e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain SUB1_ProdP9 PF18213.1 EON97050.1 - 0.03 14.2 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 DUF2880 PF11082.8 EON97050.1 - 0.036 14.4 1.0 0.072 13.4 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2880) K_channel_TID PF07941.11 EON97050.1 - 3.2 8.3 8.0 7.3 7.1 8.0 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF1682 PF07946.14 EON97050.1 - 8 5.6 9.1 16 4.6 9.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) LSM PF01423.22 EON97052.1 - 1.3e-20 72.8 0.2 1.7e-20 72.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 EON97052.1 - 0.004 17.7 11.8 0.0069 16.9 11.8 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 DUF150_C PF17384.2 EON97052.1 - 0.024 14.8 0.1 0.042 14.0 0.1 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain SET PF00856.28 EON97054.1 - 5.8e-16 59.3 0.9 5.8e-16 59.3 0.9 2.5 2 1 0 2 2 2 1 SET domain AWS PF17907.1 EON97054.1 - 4e-07 29.9 8.7 1.1e-06 28.6 8.7 1.7 1 0 0 1 1 1 1 AWS domain Zn_clus PF00172.18 EON97057.1 - 0.087 13.0 8.1 0.15 12.2 8.1 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_43 PF04616.14 EON97058.1 - 2.8e-27 95.8 4.3 7.2e-26 91.2 4.3 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Peptidase_S9_N PF02897.15 EON97058.1 - 0.075 11.8 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Aldo_ket_red PF00248.21 EON97060.1 - 3e-42 144.8 0.1 1.6e-40 139.1 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family APH PF01636.23 EON97062.1 - 5e-09 36.4 0.0 6.6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EON97062.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aldedh PF00171.22 EON97063.1 - 1.7e-76 257.6 0.0 1.9e-76 257.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF35_N PF12172.8 EON97063.1 - 0.2 11.6 0.1 0.36 10.7 0.1 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DAO PF01266.24 EON97064.1 - 6.4e-22 78.6 0.0 8.1e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Cas_csx3 PF09620.10 EON97065.1 - 0.0069 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_csx3) ADH_N PF08240.12 EON97066.1 - 7.1e-18 64.5 0.5 3.8e-17 62.1 0.5 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON97066.1 - 8.5e-07 29.0 0.1 1.4e-05 25.1 0.1 2.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EON97066.1 - 0.0008 18.9 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus HMGL-like PF00682.19 EON97067.1 - 1.1e-32 113.6 0.2 1.3e-32 113.4 0.2 1.1 1 0 0 1 1 1 1 HMGL-like DUF362 PF04015.12 EON97067.1 - 0.069 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF362) Myb_DNA-binding PF00249.31 EON97068.1 - 2.5e-06 27.6 0.0 5.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Tyrosinase PF00264.20 EON97069.1 - 6.5e-34 118.2 2.7 1.4e-33 117.0 2.7 1.6 1 1 0 1 1 1 1 Common central domain of tyrosinase DS PF01916.17 EON97070.1 - 5.8e-124 413.0 0.0 7.2e-124 412.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase MFS_1 PF07690.16 EON97071.1 - 9.6e-41 139.9 27.2 9.6e-41 139.9 27.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Tweety PF04906.13 EON97071.1 - 0.23 10.1 2.6 0.54 8.9 2.6 1.6 1 0 0 1 1 1 0 Tweety Amidohydro_3 PF07969.11 EON97072.1 - 8.1e-15 55.2 0.3 1.1e-11 44.9 0.0 3.2 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 EON97072.1 - 1.6e-12 47.4 0.0 2.4e-11 43.6 0.0 2.5 3 0 0 3 3 3 1 Amidohydrolase family Eno-Rase_NADH_b PF12242.8 EON97072.1 - 0.034 13.9 0.1 0.1 12.3 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SBF PF01758.16 EON97073.1 - 1.9e-29 102.8 9.0 1.4e-19 70.6 1.4 2.3 1 1 1 2 2 2 2 Sodium Bile acid symporter family zf-C2H2_6 PF13912.6 EON97073.1 - 0.2 11.7 0.1 0.35 10.9 0.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger HKR_ArcB_TM PF18415.1 EON97073.1 - 1.6 9.6 9.8 3.9 8.3 0.4 2.9 3 0 0 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain Iso_dh PF00180.20 EON97074.1 - 1.2e-99 333.7 0.0 1.4e-99 333.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Peptidase_M24 PF00557.24 EON97075.1 - 2.5e-47 161.3 0.1 3e-47 161.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EON97075.1 - 3.1e-22 78.6 9.3 6.3e-22 77.6 9.3 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EON97075.1 - 0.00033 20.7 6.9 0.0008 19.4 6.9 1.7 1 0 0 1 1 1 1 MYND finger MutS_V PF00488.21 EON97076.1 - 8.9e-67 224.8 0.3 1.6e-66 224.0 0.3 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EON97076.1 - 4.9e-41 141.1 0.2 1.1e-40 139.9 0.2 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EON97076.1 - 1.6e-32 112.1 0.0 3.3e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EON97076.1 - 1.8e-14 54.2 0.0 5.6e-14 52.6 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EON97076.1 - 1.5e-11 44.5 0.2 3.3e-11 43.4 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV FAD_binding_3 PF01494.19 EON97076.1 - 2.6e-11 43.4 0.0 8.2e-11 41.7 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain AAA_23 PF13476.6 EON97076.1 - 0.0095 16.5 1.6 0.015 15.8 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EON97076.1 - 0.05 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 EON97076.1 - 0.054 13.3 0.2 0.15 11.9 0.2 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 EON97076.1 - 0.1 12.2 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 EON97076.1 - 4.6 5.4 9.1 5.5 5.2 7.7 1.8 2 0 0 2 2 2 0 CDC45-like protein Abhydrolase_1 PF00561.20 EON97080.1 - 2.2e-06 27.5 0.0 3e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Egh16-like PF11327.8 EON97081.1 - 1.8e-51 175.2 12.9 1.8e-51 175.2 12.9 2.1 2 0 0 2 2 2 1 Egh16-like virulence factor Izumo-Ig PF16706.5 EON97081.1 - 0.079 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Hydrolase_4 PF12146.8 EON97082.1 - 1.9e-11 43.7 0.8 2.1e-10 40.3 0.8 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON97082.1 - 2.5e-10 41.3 1.4 2.5e-10 41.3 1.4 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON97082.1 - 1.2e-09 38.2 1.0 1.7e-09 37.7 1.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.12 EON97082.1 - 0.0048 15.9 0.0 0.0067 15.4 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 EON97082.1 - 0.0075 16.1 0.4 0.028 14.2 0.1 1.9 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EON97082.1 - 0.017 15.0 1.2 0.032 14.1 1.2 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.22 EON97082.1 - 0.15 12.0 0.1 0.23 11.4 0.1 1.2 1 0 0 1 1 1 0 Cutinase Abhydrolase_1 PF00561.20 EON97083.1 - 3.1e-05 23.8 0.0 7.5e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON97083.1 - 0.00012 21.4 0.0 0.00052 19.4 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON97083.1 - 0.00019 22.1 0.0 0.00025 21.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EON97083.1 - 0.027 14.6 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein gpD PF02925.16 EON97083.1 - 0.055 13.4 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage scaffolding protein D Polyketide_cyc2 PF10604.9 EON97085.1 - 0.0015 18.8 0.2 0.0019 18.5 0.2 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport fn3 PF00041.21 EON97086.1 - 4.9e-17 62.1 0.5 1.5e-07 31.7 0.1 2.8 3 0 0 3 3 3 2 Fibronectin type III domain Lipase_GDSL_2 PF13472.6 EON97086.1 - 5.2e-10 40.0 3.6 2.3e-09 37.9 0.5 2.7 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EON97086.1 - 2.6e-05 24.3 0.0 5.4e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FAD_binding_3 PF01494.19 EON97087.1 - 2.5e-21 76.3 0.0 3.2e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EON97087.1 - 3.3e-06 26.6 0.0 6.8e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON97087.1 - 1.9e-05 24.8 0.1 7e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EON97087.1 - 9.2e-05 22.2 0.0 0.00058 19.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EON97087.1 - 0.00041 20.8 0.0 0.0016 18.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EON97087.1 - 0.00064 19.1 0.0 0.00093 18.5 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EON97087.1 - 0.0022 17.2 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.10 EON97087.1 - 0.0028 16.8 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase HI0933_like PF03486.14 EON97087.1 - 0.0028 16.4 0.0 0.0039 15.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 EON97087.1 - 0.0073 15.7 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EON97087.1 - 0.023 14.6 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 EON97087.1 - 0.058 12.2 0.1 0.35 9.7 0.1 2.1 3 0 0 3 3 3 0 Tryptophan halogenase NMT_C PF02799.15 EON97088.1 - 1.6e-85 285.9 0.0 2.5e-85 285.3 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EON97088.1 - 7.7e-72 240.4 0.2 2.2e-71 238.8 0.0 1.8 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EON97088.1 - 5.2e-06 26.6 0.1 0.00037 20.6 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON97088.1 - 0.0032 17.7 0.1 0.0091 16.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EON97088.1 - 0.021 15.5 0.1 0.061 14.0 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1576 PF07613.11 EON97088.1 - 0.029 13.9 0.0 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1576) Cornichon PF03311.14 EON97089.1 - 1e-49 167.9 11.0 1.2e-49 167.7 11.0 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.32 EON97090.1 - 5.4e-33 112.5 8.6 9.7e-07 29.4 0.2 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON97090.1 - 2.3e-14 53.5 0.1 6.2e-06 26.4 0.1 4.0 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EON97090.1 - 0.0032 17.4 0.6 0.16 11.9 0.2 2.7 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 EON97090.1 - 0.0068 15.5 0.2 0.026 13.6 0.2 1.8 1 1 1 2 2 2 2 Coatomer WD associated region DUF3638 PF12340.8 EON97092.1 - 1.2e-84 283.2 1.0 1.8e-60 204.1 0.1 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EON97092.1 - 4.3e-16 58.0 0.2 8.5e-16 57.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Spore_YpjB PF09577.10 EON97092.1 - 0.085 12.7 0.0 0.55 10.0 0.0 2.1 1 1 1 2 2 2 0 Sporulation protein YpjB (SpoYpjB) MFS_1 PF07690.16 EON97093.1 - 2.7e-26 92.3 12.3 3.2e-26 92.1 12.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON97093.1 - 8.9e-06 24.8 7.4 1.2e-05 24.4 7.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Bac_luciferase PF00296.20 EON97094.1 - 5.9e-72 242.8 0.4 7.3e-72 242.4 0.4 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Bac_luciferase PF00296.20 EON97095.1 - 1.2e-20 74.2 0.3 2.2e-20 73.3 0.3 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 EON97095.1 - 2.1e-08 33.5 8.2 1.3e-07 30.9 8.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Aldo_ket_red PF00248.21 EON97096.1 - 1.4e-34 119.6 0.0 1.6e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pec_lyase_C PF00544.19 EON97097.1 - 2.7e-13 50.0 13.1 6e-13 48.9 7.7 2.7 2 1 0 2 2 2 1 Pectate lyase Beta_helix PF13229.6 EON97097.1 - 0.0008 19.3 21.6 0.011 15.6 20.2 2.4 1 1 1 2 2 2 2 Right handed beta helix region CfAFP PF05264.11 EON97097.1 - 0.056 13.4 0.1 0.056 13.4 0.1 2.9 3 0 0 3 3 3 0 Choristoneura fumiferana antifreeze protein (CfAFP) ADH_N PF08240.12 EON97098.1 - 3.5e-25 88.0 2.2 5.7e-25 87.3 2.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON97098.1 - 3.8e-18 65.7 0.0 7.5e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON97098.1 - 4.7e-09 37.4 0.0 7.4e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EON97098.1 - 0.00097 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EON97098.1 - 0.0044 16.4 0.0 0.0066 15.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ran_BP1 PF00638.18 EON97099.1 - 5.1e-50 168.8 1.1 8.2e-50 168.2 1.1 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 EON97099.1 - 0.00088 19.2 0.2 0.0032 17.4 0.2 1.8 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 EON97099.1 - 0.012 15.9 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 VID27 PH-like domain PS-DH PF14765.6 EON97099.1 - 0.059 12.6 0.2 0.12 11.6 0.1 1.5 2 0 0 2 2 2 0 Polyketide synthase dehydratase GrpB PF04229.14 EON97100.1 - 5.1e-50 169.8 0.0 6.1e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 GrpB protein Phosducin PF02114.16 EON97101.1 - 4.7e-11 42.1 3.5 2.2e-10 39.9 0.1 2.7 2 1 0 2 2 2 1 Phosducin WD40 PF00400.32 EON97102.1 - 1.6e-37 126.9 19.1 3.1e-07 31.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON97102.1 - 3.6e-14 52.8 0.1 0.00026 21.2 0.1 4.6 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EON97102.1 - 0.0001 22.3 0.0 0.11 12.4 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EON97102.1 - 0.00014 21.0 0.1 1.1 8.2 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EON97102.1 - 0.0015 17.9 0.0 0.094 12.0 0.0 2.9 2 1 1 4 4 4 1 WD40-like domain Glyco_hydro_18 PF00704.28 EON97103.1 - 5.9e-69 233.2 1.0 8.7e-69 232.6 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DNA_ligase_A_M PF01068.21 EON97104.1 - 2.1e-46 158.2 0.0 6.6e-46 156.5 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EON97104.1 - 2.4e-42 145.2 0.0 4.6e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 EON97104.1 - 8e-16 58.8 0.0 1.9e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 RNA ligase BRCT_2 PF16589.5 EON97104.1 - 2.8e-15 56.5 0.0 9.4e-09 35.6 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 EON97104.1 - 8.8e-15 55.1 0.0 3.6e-14 53.2 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_IV PF11411.8 EON97104.1 - 5.8e-05 23.1 0.0 0.00015 21.8 0.0 1.8 1 0 0 1 1 1 1 DNA ligase IV LIG3_BRCT PF16759.5 EON97104.1 - 0.0001 22.5 1.2 0.038 14.3 0.3 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain BRCT PF00533.26 EON97104.1 - 0.0011 19.3 0.0 0.14 12.5 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain NIBRIN_BRCT_II PF16508.5 EON97104.1 - 0.0013 19.0 0.2 0.0054 17.0 0.0 2.1 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein mRNA_cap_enzyme PF01331.19 EON97104.1 - 0.035 13.9 0.0 6.4 6.6 0.0 2.5 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain Polysacc_deac_1 PF01522.21 EON97105.1 - 3.7e-12 46.2 0.0 6.4e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Abhydrolase_1 PF00561.20 EON97106.1 - 2.9e-10 40.2 0.0 4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON97106.1 - 0.0028 16.9 0.0 0.004 16.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON97106.1 - 0.0061 17.2 0.0 0.0092 16.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EON97106.1 - 0.083 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Ndr family Transp_cyt_pur PF02133.15 EON97107.1 - 1.2e-42 146.3 8.2 1.4e-42 146.0 8.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin YEATS PF03366.16 EON97108.1 - 2.2e-20 72.4 0.1 5.8e-20 71.1 0.1 1.8 1 0 0 1 1 1 1 YEATS family BET PF17035.5 EON97108.1 - 0.0094 16.1 0.2 0.019 15.1 0.2 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Peptidase_S10 PF00450.22 EON97109.1 - 8.2e-75 252.8 0.0 1.1e-74 252.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase EspB PF05802.11 EON97110.1 - 0.051 13.6 4.4 2.4 8.1 0.1 2.4 2 0 0 2 2 2 0 Enterobacterial EspB protein CREPT PF16566.5 EON97110.1 - 0.2 11.8 1.4 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour UPRTase PF14681.6 EON97111.1 - 3.7e-71 238.9 0.0 1.4e-70 236.9 0.0 1.7 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EON97111.1 - 0.0051 16.3 0.0 0.015 14.8 0.0 1.8 3 0 0 3 3 3 1 Phosphoribosyl transferase domain TMP-TENI PF02581.17 EON97111.1 - 0.13 11.6 0.2 2.7 7.3 0.1 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase Amidase PF01425.21 EON97112.1 - 2.4e-72 244.3 0.0 3.9e-72 243.6 0.0 1.3 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 EON97114.1 - 8e-13 48.0 20.5 1.9e-10 40.2 7.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EON97114.1 - 2.5e-11 42.7 4.6 1.7e-10 40.0 4.8 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) 7TMR-DISM_7TM PF07695.11 EON97114.1 - 0.014 15.3 4.2 0.014 15.3 4.2 2.0 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF5325 PF17259.2 EON97114.1 - 0.086 12.7 0.2 0.086 12.7 0.2 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5325) Sensor PF13796.6 EON97114.1 - 3 7.9 13.1 1.9 8.5 4.1 2.8 3 1 0 3 3 3 0 Putative sensor DUF2207 PF09972.9 EON97114.1 - 8 5.1 12.2 0.083 11.6 0.9 2.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) Oxidored_FMN PF00724.20 EON97115.1 - 1.4e-95 320.5 0.0 1.8e-95 320.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PRAI PF00697.22 EON97115.1 - 0.038 13.7 0.0 0.087 12.6 0.0 1.5 2 0 0 2 2 2 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Tautomerase PF01361.21 EON97115.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme AP_endonuc_2 PF01261.24 EON97115.1 - 0.098 12.1 0.1 1.4 8.3 0.0 2.4 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel DUF4449 PF14613.6 EON97116.1 - 1.3e-69 233.5 4.6 1.3e-69 233.5 4.6 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Prp18 PF02840.15 EON97116.1 - 0.00051 20.1 4.9 0.084 12.9 0.0 3.5 1 1 2 3 3 3 2 Prp18 domain MRP-S28 PF10213.9 EON97116.1 - 0.084 13.3 0.1 0.084 13.3 0.1 3.2 4 0 0 4 4 4 0 Mitochondrial ribosomal subunit protein JHBP PF06585.11 EON97116.1 - 0.13 11.4 2.4 1 8.5 2.4 2.3 1 1 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) DUF4404 PF14357.6 EON97116.1 - 2 9.1 7.9 8.4 7.1 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) FAD_binding_4 PF01565.23 EON97117.1 - 0.00032 20.5 0.7 0.00058 19.6 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EON97117.1 - 0.012 15.7 0.1 0.024 14.7 0.1 1.5 1 0 0 1 1 1 0 Berberine and berberine like Glyco_hydro_1 PF00232.18 EON97118.1 - 1.6e-45 155.3 0.2 2.3e-38 131.8 0.1 2.5 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 Cellulase PF00150.18 EON97118.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.16 EON97119.1 - 2.3e-13 49.8 36.6 3.8e-13 49.1 36.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EON97119.1 - 1.6e-11 44.2 7.7 1.6e-11 44.2 7.7 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Na_Ca_ex PF01699.24 EON97120.1 - 4.9e-39 133.7 40.9 4.1e-20 72.3 17.9 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MutS_V PF00488.21 EON97120.1 - 4.8e-26 92.0 0.0 8.7e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EON97120.1 - 5.5e-26 92.0 0.8 1.4e-25 90.6 0.8 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 EON97120.1 - 2.1e-05 24.9 0.0 0.00011 22.4 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EON97120.1 - 0.00018 21.8 0.0 0.00033 20.9 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV RNA_ligase PF09414.10 EON97121.1 - 8e-29 101.0 0.0 1.5e-28 100.2 0.0 1.4 1 0 0 1 1 1 1 RNA ligase Dynamin_N PF00350.23 EON97122.1 - 8.9e-31 107.2 0.1 2.4e-30 105.8 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 EON97122.1 - 1e-14 54.5 0.0 8.9e-13 48.1 0.0 2.5 2 1 0 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.23 EON97122.1 - 2.1e-05 24.5 0.0 6e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase MLTR_LBD PF17765.1 EON97122.1 - 0.068 13.3 0.7 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain Metal_resist PF13801.6 EON97122.1 - 0.087 13.0 0.6 0.51 10.5 0.0 2.7 2 0 0 2 2 2 0 Heavy-metal resistance AAA_23 PF13476.6 EON97122.1 - 0.15 12.5 1.5 2.1 8.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 EON97122.1 - 0.17 12.1 0.0 0.8 9.9 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ADH_zinc_N PF00107.26 EON97123.1 - 1.3e-24 86.6 0.0 2.3e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON97123.1 - 6e-21 75.9 0.0 1.5e-20 74.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON97123.1 - 1.3e-06 28.3 0.2 3.2e-06 27.0 0.2 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PhyH PF05721.13 EON97124.1 - 1.3e-11 45.2 0.0 1.9e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF917 PF06032.12 EON97125.1 - 2.9e-106 355.2 0.8 5.3e-106 354.4 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 EON97125.1 - 3.2e-08 33.2 5.5 0.00091 18.6 1.4 2.7 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase COesterase PF00135.28 EON97126.1 - 1.4e-70 238.6 0.0 2.1e-70 238.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EON97126.1 - 1.4e-05 25.1 0.0 3.1e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyoxalase PF00903.25 EON97127.1 - 5.9e-05 23.3 0.2 0.00027 21.1 0.0 2.1 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GMC_oxred_C PF05199.13 EON97128.1 - 6.1e-40 137.1 0.0 9.9e-40 136.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EON97128.1 - 3.5e-37 128.4 0.0 6.2e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Beta-lactamase PF00144.24 EON97129.1 - 1.5e-43 149.3 0.1 2.1e-43 148.9 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EON97129.1 - 4.9e-13 49.4 0.0 1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) DUF2235 PF09994.9 EON97130.1 - 7.8e-87 291.3 0.1 1.9e-86 290.0 0.1 1.6 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BetaGal_dom2 PF10435.9 EON97131.1 - 1.7e-60 204.0 8.4 2.7e-60 203.3 6.5 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 EON97131.1 - 1.1e-59 200.0 5.0 4.7e-32 110.9 0.1 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 EON97131.1 - 8.5e-24 82.9 0.1 2.3e-23 81.6 0.1 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_35 PF01301.19 EON97131.1 - 4.3e-18 66.0 0.4 2.5e-15 56.9 2.8 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 35 Fil_haemagg_2 PF13332.6 EON97131.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Hemagglutinin repeat PhyH PF05721.13 EON97133.1 - 0.019 15.2 0.3 0.066 13.5 0.3 2.0 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) adh_short PF00106.25 EON97134.1 - 1.9e-40 138.4 0.2 3.1e-40 137.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON97134.1 - 1.1e-24 87.3 0.1 7.6e-24 84.6 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 EON97134.1 - 0.00011 21.9 0.1 0.001 18.7 0.2 2.0 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 EON97134.1 - 0.0013 18.3 0.2 0.0039 16.7 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EON97134.1 - 0.0022 17.9 0.4 0.0062 16.5 0.4 1.6 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EON97134.1 - 0.12 12.1 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Aldo_ket_red PF00248.21 EON97135.1 - 2.5e-29 102.4 0.0 4.4e-22 78.6 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family FAD_binding_3 PF01494.19 EON97136.1 - 3.8e-15 56.0 1.3 1.6e-13 50.7 1.3 2.2 1 1 0 1 1 1 1 FAD binding domain Aminotran_4 PF01063.19 EON97137.1 - 3.1e-23 82.8 0.0 3.8e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV SepSecS PF05889.13 EON97137.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Clr5 PF14420.6 EON97138.1 - 4.1e-19 68.6 3.0 9.3e-19 67.4 2.2 2.1 2 0 0 2 2 2 1 Clr5 domain DUF5021 PF16424.5 EON97138.1 - 0.12 12.3 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5021) FTR1 PF03239.14 EON97139.1 - 0.045 12.9 0.0 0.052 12.7 0.0 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family RSN1_7TM PF02714.15 EON97141.1 - 8.2e-81 271.3 21.4 1.3e-80 270.6 21.4 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EON97141.1 - 3.9e-40 137.9 0.0 5.7e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EON97141.1 - 3.7e-36 124.2 0.3 3.7e-36 124.2 0.3 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Alpha-amylase PF00128.24 EON97142.1 - 2e-11 44.1 0.0 2.6e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CFEM PF05730.11 EON97143.1 - 1.2e-13 51.0 10.6 1.2e-13 51.0 10.6 1.5 2 0 0 2 2 2 1 CFEM domain WD40 PF00400.32 EON97144.1 - 6.3e-59 194.6 30.0 8.9e-10 39.0 0.5 9.3 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON97144.1 - 3.8e-24 84.8 5.8 0.00041 20.6 0.0 7.0 4 2 3 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EON97144.1 - 1.1e-08 35.2 0.3 0.0045 16.9 0.0 3.9 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EON97144.1 - 1.3e-08 34.2 0.0 1 8.3 0.0 5.2 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EON97144.1 - 7.7e-06 24.8 0.2 0.13 10.9 0.0 4.1 4 0 0 4 4 4 1 Nucleoporin Nup120/160 PD40 PF07676.12 EON97144.1 - 2.2e-05 24.2 0.3 2.4 8.2 0.0 4.2 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EON97144.1 - 0.00082 18.8 0.0 0.73 9.1 0.0 3.4 4 0 0 4 4 4 1 WD40-like domain Nbas_N PF15492.6 EON97144.1 - 0.005 16.2 0.3 9 5.5 0.0 4.0 4 2 1 5 5 5 1 Neuroblastoma-amplified sequence, N terminal NLE PF08154.12 EON97144.1 - 0.0098 16.4 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain PQQ_3 PF13570.6 EON97144.1 - 0.041 14.4 1.7 4.1 8.0 0.2 4.5 5 1 1 6 6 6 0 PQQ-like domain DUF5046 PF16465.5 EON97144.1 - 0.046 13.2 0.1 13 5.1 0.0 3.6 2 1 1 4 4 4 0 Domain of unknown function (DUF5046) DPPIV_N PF00930.21 EON97144.1 - 0.086 11.6 0.4 3.2 6.4 0.0 2.9 4 0 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.9 EON97144.1 - 1.9 8.3 3.6 11 5.8 0.0 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Glyco_transf_20 PF00982.21 EON97145.1 - 2.5e-165 550.7 0.1 3.8e-165 550.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EON97145.1 - 7.9e-45 152.8 0.0 1.3e-44 152.1 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 EON97145.1 - 0.1 12.3 0.3 0.2 11.3 0.3 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain MFS_1 PF07690.16 EON97146.1 - 1.8e-13 50.2 38.7 4.1e-07 29.3 22.6 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily S1FA PF04689.13 EON97146.1 - 4.4 7.5 5.4 7.3 6.8 0.3 3.3 3 0 0 3 3 3 0 DNA binding protein S1FA FAA_hydrolase PF01557.18 EON97147.1 - 1.5e-62 211.1 0.0 2.2e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Colipase PF01114.18 EON97148.1 - 0.018 14.7 3.8 0.03 14.0 3.8 1.4 1 0 0 1 1 1 0 Colipase, N-terminal domain PepSY_2 PF13670.6 EON97148.1 - 0.78 9.8 4.9 8.9 6.4 0.5 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain GFA PF04828.14 EON97149.1 - 4.1e-11 43.1 2.3 4.1e-11 43.1 2.3 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PhyH PF05721.13 EON97150.1 - 2e-13 51.1 0.0 3.1e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RHH_5 PF07878.11 EON97150.1 - 0.15 12.0 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 K_trans PF02705.16 EON97152.1 - 3e-180 600.3 17.9 3.5e-180 600.0 17.9 1.0 1 0 0 1 1 1 1 K+ potassium transporter Glyco_hydro_3_C PF01915.22 EON97153.1 - 5.3e-49 166.9 0.0 9e-49 166.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EON97153.1 - 3.2e-22 79.3 0.1 5.5e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EON97153.1 - 1.2e-12 47.8 0.3 2.3e-12 46.8 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EON97153.1 - 9.8e-09 35.2 0.1 5.8e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 PA14 domain GLEYA PF10528.9 EON97154.1 - 1.4e-26 92.7 3.3 1.4e-26 92.7 3.3 1.8 2 0 0 2 2 2 1 GLEYA domain PA14 PF07691.12 EON97154.1 - 0.021 14.6 0.1 0.048 13.5 0.1 1.6 1 0 0 1 1 1 0 PA14 domain Ank PF00023.30 EON97157.1 - 0.03 14.8 0.1 1.5 9.4 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat AAA_12 PF13087.6 EON97158.1 - 2.2e-38 131.9 0.2 4.6e-38 130.8 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EON97158.1 - 7.9e-23 81.6 0.0 3.2e-22 79.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EON97158.1 - 7.5e-08 32.8 1.5 9.9e-07 29.2 0.3 2.8 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EON97158.1 - 5.7e-07 29.1 1.3 0.0098 15.2 0.0 2.6 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EON97158.1 - 7.5e-05 22.5 1.2 0.0041 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EON97158.1 - 0.012 15.6 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 EON97158.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 EON97158.1 - 0.16 11.7 0.1 20 4.8 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EON97158.1 - 0.19 12.0 0.6 1.1 9.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain GH131_N PF18271.1 EON97159.1 - 0.15 11.7 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycoside hydrolase 131 catalytic N-terminal domain adh_short_C2 PF13561.6 EON97161.1 - 7.1e-17 61.7 0.1 9e-17 61.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON97161.1 - 2.6e-16 59.7 0.0 4.4e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase HTH_39 PF14090.6 EON97162.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Amidase PF01425.21 EON97163.1 - 1.9e-35 122.7 2.0 2e-28 99.6 1.2 2.6 1 1 1 2 2 2 2 Amidase VbhA PF18495.1 EON97163.1 - 0.052 13.4 0.0 0.5 10.3 0.0 2.3 2 0 0 2 2 2 0 Antitoxin VbhA Collar PF07484.12 EON97163.1 - 0.058 13.4 0.0 4 7.5 0.0 2.7 2 0 0 2 2 2 0 Phage Tail Collar Domain DHDPS PF00701.22 EON97164.1 - 1.5e-41 142.1 0.0 1.8e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fructosamin_kin PF03881.14 EON97165.1 - 1.4e-30 106.5 0.0 1.7e-30 106.2 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EON97165.1 - 0.0001 22.3 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EON97165.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF3463 PF11946.8 EON97165.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) Cyclin_N PF00134.23 EON97166.1 - 2.5e-15 56.4 0.0 4e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EON97166.1 - 1.2e-07 32.2 0.1 1.2e-07 32.2 0.1 2.4 2 2 0 2 2 2 1 Cyclin Apt1 PF10351.9 EON97166.1 - 0.0026 16.7 0.9 0.0035 16.3 0.9 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Herpes_capsid PF06112.11 EON97166.1 - 1.3 9.0 10.5 2.6 8.1 10.5 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein MAGE_N PF12440.8 EON97166.1 - 5.9 7.6 16.5 15 6.3 16.5 1.6 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Cupin_2 PF07883.11 EON97167.1 - 1.5e-13 50.3 1.6 7.7e-13 48.0 0.1 2.5 2 1 1 3 3 3 1 Cupin domain Cupin_1 PF00190.22 EON97167.1 - 2.7e-06 27.1 0.0 3.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 EON97167.1 - 1.7e-05 24.4 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) 3-HAO PF06052.12 EON97167.1 - 0.00043 19.9 0.0 0.00046 19.8 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase EutQ PF06249.12 EON97167.1 - 0.0034 17.1 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_7 PF12973.7 EON97167.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 ChrR Cupin-like domain Cupin_6 PF12852.7 EON97167.1 - 0.028 14.2 0.0 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 Cupin Pirin PF02678.16 EON97167.1 - 0.034 14.1 0.1 0.042 13.8 0.1 1.2 1 0 0 1 1 1 0 Pirin ARD PF03079.14 EON97167.1 - 0.045 13.9 0.1 0.058 13.6 0.1 1.3 1 0 0 1 1 1 0 ARD/ARD' family AraC_binding PF02311.19 EON97167.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Fungal_trans_2 PF11951.8 EON97169.1 - 3e-18 65.8 0.9 3.8e-18 65.5 0.9 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 EON97170.1 - 5.2e-70 235.8 0.0 6.7e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON97170.1 - 4.1e-30 104.9 0.0 5.4e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EON97170.1 - 0.0011 18.4 0.0 0.0022 17.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EON97170.1 - 0.01 14.8 0.0 0.13 11.2 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 EON97170.1 - 0.011 15.7 0.1 0.02 14.8 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family WSC PF01822.19 EON97171.1 - 2.9e-36 123.5 23.6 6.8e-20 71.1 8.4 3.8 3 1 0 3 3 3 2 WSC domain Apt1 PF10351.9 EON97171.1 - 0.32 9.8 8.5 0.46 9.3 8.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 EON97171.1 - 1.1 9.1 11.6 1.7 8.5 11.6 1.3 1 0 0 1 1 1 0 SPX domain Hid1 PF12722.7 EON97171.1 - 8 4.5 9.1 12 3.8 9.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAD_binding_4 PF01565.23 EON97172.1 - 5.8e-25 87.7 0.3 1.1e-24 86.7 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EON97172.1 - 0.17 12.0 0.1 0.43 10.7 0.1 1.7 1 0 0 1 1 1 0 Berberine and berberine like Hira PF07569.11 EON97173.1 - 7.5e-89 297.2 0.1 3.3e-88 295.2 0.0 2.0 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 EON97173.1 - 1.6e-30 104.7 23.6 5.4e-05 23.9 0.0 9.4 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON97173.1 - 9.5e-14 51.5 0.1 0.061 13.6 0.0 6.2 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EON97173.1 - 9.8e-12 44.4 0.8 2.2e-11 43.3 0.8 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 EON97173.1 - 3.6e-06 26.8 1.1 1.9 8.5 0.3 4.7 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EON97173.1 - 9.2e-06 24.8 0.3 0.095 11.6 0.0 4.8 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1996 PF09362.10 EON97174.1 - 5e-12 46.3 1.6 5e-12 46.3 1.6 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Amidase PF01425.21 EON97175.1 - 2.6e-70 237.6 0.0 2.4e-69 234.4 0.0 1.9 1 1 0 1 1 1 1 Amidase HEAT_EZ PF13513.6 EON97176.1 - 3e-18 65.9 21.2 7.9e-06 26.3 0.0 10.9 11 2 1 12 12 10 3 HEAT-like repeat HEAT_2 PF13646.6 EON97176.1 - 8.5e-18 64.5 18.6 0.0006 20.2 0.0 10.1 5 4 6 11 11 11 5 HEAT repeats HEAT PF02985.22 EON97176.1 - 1.4e-14 53.0 6.8 0.0072 16.5 0.0 9.9 11 0 0 11 11 11 2 HEAT repeat Adaptin_N PF01602.20 EON97176.1 - 1.6e-10 40.2 0.8 0.015 13.9 0.0 5.1 5 1 0 5 5 5 3 Adaptin N terminal region IBN_N PF03810.19 EON97176.1 - 3.4e-10 39.7 1.6 5.1e-07 29.5 0.0 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 EON97176.1 - 7.4e-10 39.3 0.1 0.0072 16.9 0.0 5.3 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region Arm PF00514.23 EON97176.1 - 1.6e-08 34.3 5.9 0.33 11.1 0.0 8.2 9 0 0 9 9 8 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EON97176.1 - 2.6e-08 34.1 6.7 0.00016 21.7 0.0 4.5 4 2 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EON97176.1 - 4.3e-05 22.8 3.3 0.14 11.3 0.4 3.9 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 EON97176.1 - 6.5e-05 22.6 0.7 0.15 11.6 0.0 4.1 5 1 1 6 6 6 2 CLASP N terminal ParcG PF10274.9 EON97176.1 - 0.00017 21.8 0.8 0.059 13.5 0.2 3.7 4 0 0 4 4 4 1 Parkin co-regulated protein INTS5_C PF14838.6 EON97176.1 - 0.00017 20.4 0.4 0.09 11.4 0.3 3.2 3 0 0 3 3 3 2 Integrator complex subunit 5 C-terminus UME PF08064.13 EON97176.1 - 0.00022 21.1 0.0 0.035 14.0 0.1 3.6 3 0 0 3 3 3 1 UME (NUC010) domain DRIM PF07539.12 EON97176.1 - 0.00059 18.3 6.8 0.073 11.4 0.9 4.0 2 2 0 3 3 3 2 Down-regulated in metastasis RIX1 PF08167.12 EON97176.1 - 0.001 18.8 0.0 3.5 7.3 0.0 3.8 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis TIP120 PF08623.10 EON97176.1 - 0.0016 18.2 0.8 0.11 12.3 0.0 3.5 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) V-ATPase_H_C PF11698.8 EON97176.1 - 0.0075 16.4 1.0 2.8 8.1 0.0 4.8 5 1 0 5 5 4 1 V-ATPase subunit H RTP1_C1 PF10363.9 EON97176.1 - 0.024 14.8 0.2 3.5 7.8 0.0 4.1 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 EON97176.1 - 0.14 11.7 1.0 8.3 5.8 0.0 3.9 5 1 0 5 5 5 0 Tti2 family FlaF PF07309.11 EON97176.1 - 0.18 11.8 1.0 3.1 7.8 0.0 3.3 3 0 0 3 3 3 0 Flagellar protein FlaF YukD PF08817.10 EON97176.1 - 0.25 12.0 2.0 27 5.6 0.0 4.5 4 0 0 4 4 4 0 WXG100 protein secretion system (Wss), protein YukD p450 PF00067.22 EON97177.1 - 1.2e-59 202.3 0.0 1.6e-59 201.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HECT PF00632.25 EON97178.1 - 3.1e-73 246.9 0.0 5e-73 246.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 EON97178.1 - 0.00021 21.2 1.1 2.4 8.3 0.0 5.4 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat BUD22 PF09073.10 EON97178.1 - 2.6 7.3 30.6 0.38 10.0 0.9 2.9 3 0 0 3 3 3 0 BUD22 Zds_C PF08632.10 EON97179.1 - 2.8e-28 97.4 0.8 5.1e-28 96.6 0.8 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2076 PF09849.9 EON97179.1 - 0.13 12.3 0.2 0.13 12.3 0.2 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) SUIM_assoc PF16619.5 EON97179.1 - 0.99 9.5 22.4 0.065 13.3 14.8 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Atrophin-1 PF03154.15 EON97179.1 - 3.7 5.7 16.7 0.023 13.0 5.6 2.1 2 0 0 2 2 2 0 Atrophin-1 family DUF5308 PF17233.2 EON97179.1 - 10 6.4 18.6 0.21 11.8 3.0 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5308) MFS_1 PF07690.16 EON97180.1 - 7.9e-18 64.5 5.4 9.9e-18 64.2 5.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Thiol_cytolys_C PF17440.2 EON97180.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Thiol-activated cytolysin beta sandwich domain Rap1_C PF11626.8 EON97181.1 - 7.4e-22 77.2 0.0 1.1e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain FlgO PF17680.1 EON97182.1 - 0.13 12.0 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 FlgO protein Ubie_methyltran PF01209.18 EON97183.1 - 2.3e-72 243.1 0.0 2.9e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EON97183.1 - 7.3e-15 55.5 0.0 2.2e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON97183.1 - 7.4e-13 49.0 0.0 3.3e-12 46.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON97183.1 - 1.9e-09 38.2 0.0 3.3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON97183.1 - 2.4e-09 37.2 0.0 3.3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON97183.1 - 2.8e-07 30.5 0.0 4.4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain HCMV_UL124 PF17609.2 EON97183.1 - 0.018 15.2 0.2 0.039 14.1 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function MTS PF05175.14 EON97183.1 - 0.053 13.1 0.0 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_8 PF05148.15 EON97183.1 - 0.12 12.3 0.0 0.69 9.7 0.0 2.0 1 1 0 2 2 2 0 Hypothetical methyltransferase FF PF01846.19 EON97184.1 - 7.6e-10 38.8 9.4 9e-09 35.4 0.2 3.7 3 0 0 3 3 3 1 FF domain WW PF00397.26 EON97184.1 - 9.2e-10 38.4 2.0 2.5e-09 37.0 2.0 1.8 1 0 0 1 1 1 1 WW domain DUF5641 PF18701.1 EON97184.1 - 0.18 12.0 2.2 0.27 11.4 0.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5641) Tho2 PF11262.8 EON97184.1 - 0.74 9.0 9.0 0.056 12.6 3.2 1.8 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 GBP_C PF02841.14 EON97184.1 - 6.6 6.0 12.4 15 4.9 12.4 1.5 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Bac_rhamnosid6H PF17389.2 EON97185.1 - 3.5e-13 49.5 2.0 6e-11 42.2 1.1 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 EON97185.1 - 7.9e-07 28.8 0.0 2.2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF1923 PF09083.10 EON97185.1 - 0.091 12.5 0.6 3.6 7.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1923) MARVEL PF01284.23 EON97186.1 - 2.7e-07 30.7 14.6 7.2e-07 29.3 10.9 2.1 1 1 0 2 2 2 1 Membrane-associating domain Auxin_inducible PF02519.14 EON97186.1 - 0.091 12.9 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Auxin responsive protein TFIIA PF03153.13 EON97186.1 - 1.5 8.7 22.5 1.8 8.5 22.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit KAR9 PF08580.10 EON97186.1 - 2.4 6.6 8.1 3.1 6.2 8.1 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF747 PF05346.11 EON97187.1 - 5e-95 318.6 0.3 7e-77 259.0 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic membrane protein family Sugar_tr PF00083.24 EON97188.1 - 8.7e-87 291.8 15.2 1e-86 291.7 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON97188.1 - 4.7e-31 108.0 16.4 7e-31 107.4 16.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EON97188.1 - 9.7e-07 27.7 11.5 6.2e-05 21.7 1.7 2.6 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 EON97188.1 - 0.00017 20.2 4.4 0.00085 17.9 0.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 EON97188.1 - 0.00017 20.5 2.1 0.00017 20.5 2.1 2.2 2 0 0 2 2 2 2 POT family MFS_1_like PF12832.7 EON97188.1 - 0.014 14.2 0.1 0.014 14.2 0.1 2.3 2 1 0 2 2 2 0 MFS_1 like family UNC-93 PF05978.16 EON97188.1 - 0.044 13.5 6.7 0.033 13.9 2.4 2.3 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 adh_short PF00106.25 EON97189.1 - 6.9e-40 136.6 1.2 1.5e-39 135.4 1.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON97189.1 - 2.4e-38 132.0 0.5 5.7e-38 130.8 0.5 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON97189.1 - 1.7e-08 34.6 1.3 2.8e-08 33.9 1.3 1.5 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EON97189.1 - 0.071 13.0 1.5 0.11 12.4 1.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EON97189.1 - 0.12 11.9 1.5 0.089 12.2 0.3 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family OEP PF02321.18 EON97190.1 - 0.027 14.3 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein TraQ PF09679.10 EON97190.1 - 0.08 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Pro_CA PF00484.19 EON97191.1 - 1.4e-11 44.9 0.0 0.00015 22.0 0.0 2.1 1 1 1 2 2 2 2 Carbonic anhydrase Prefoldin_2 PF01920.20 EON97191.1 - 0.028 14.4 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Prefoldin subunit Complex1_LYR_2 PF13233.6 EON97193.1 - 2.8e-23 82.4 0.1 3.4e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EON97193.1 - 0.0047 16.9 0.2 0.0081 16.2 0.2 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Oxidored_molyb PF00174.19 EON97194.1 - 2.3e-43 147.8 0.0 3.2e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EON97194.1 - 3.4e-21 75.7 1.1 5.7e-21 75.0 1.1 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Ank_2 PF12796.7 EON97195.1 - 6.6e-18 65.1 0.4 1.3e-10 41.7 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EON97195.1 - 2.1e-15 55.3 1.1 9.4e-05 22.5 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EON97195.1 - 2.2e-15 56.3 6.7 2.5e-06 27.7 0.7 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EON97195.1 - 6e-13 49.0 0.8 1.7e-07 31.6 0.3 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EON97195.1 - 2.3e-11 43.7 6.0 5e-06 26.7 0.7 4.1 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Amidase PF01425.21 EON97196.1 - 2e-19 69.9 0.4 3.1e-18 66.0 0.1 2.1 2 0 0 2 2 2 2 Amidase Aha1_N PF09229.11 EON97197.1 - 2e-42 144.7 2.0 3e-42 144.1 2.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EON97197.1 - 2.3e-21 76.3 0.7 5.6e-21 75.1 0.3 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Peptidase_S58 PF03576.14 EON97198.1 - 8.7e-115 383.3 2.7 1e-114 383.1 2.7 1.1 1 0 0 1 1 1 1 Peptidase family S58 DarA_N PF18788.1 EON97198.1 - 0.073 13.2 0.1 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 Defence against restriction A N-terminal MFS_1 PF07690.16 EON97199.1 - 6e-24 84.6 15.7 7.5e-24 84.3 15.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EON97199.1 - 3.7e-10 38.9 4.1 4.2e-10 38.7 4.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EON97199.1 - 0.00079 18.4 8.0 0.001 18.0 6.8 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter DUF5392 PF17370.2 EON97199.1 - 0.44 10.6 1.3 20 5.3 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5392) DLH PF01738.18 EON97200.1 - 1.1e-22 80.7 0.0 1.2e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF604 PF04646.12 EON97201.1 - 1.5e-11 44.2 0.3 3.4e-11 43.0 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF604 Fringe PF02434.16 EON97201.1 - 2.5e-08 33.7 0.0 6.1e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 Fringe-like PIR PF00399.19 EON97202.1 - 8.9e-07 28.3 31.7 0.00056 19.4 0.8 5.1 5 0 0 5 5 5 4 Yeast PIR protein repeat zf-U1 PF06220.12 EON97203.1 - 4.8e-08 32.7 0.6 9.2e-08 31.7 0.6 1.5 1 0 0 1 1 1 1 U1 zinc finger Acetyltransf_2 PF00797.17 EON97204.1 - 3.9e-16 59.6 0.0 4.9e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase MFS_1 PF07690.16 EON97205.1 - 2.4e-21 76.0 26.3 2.3e-12 46.5 7.9 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily MMR_HSR1 PF01926.23 EON97206.1 - 2.5e-16 59.8 0.0 5e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EON97206.1 - 3.3e-09 36.6 0.0 9.2e-09 35.1 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EON97206.1 - 8.3e-05 22.2 0.0 0.0036 16.9 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EON97206.1 - 0.00013 21.9 0.1 0.0077 16.2 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EON97206.1 - 0.0023 18.0 0.0 0.099 12.7 0.1 2.2 2 0 0 2 2 2 1 Dynamin family TniB PF05621.11 EON97206.1 - 0.0064 15.9 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein ABC_tran PF00005.27 EON97206.1 - 0.0081 16.7 0.1 0.017 15.7 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EON97206.1 - 0.017 14.9 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EON97206.1 - 0.2 11.9 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF5090 PF17009.5 EON97207.1 - 3.5 7.6 5.7 3.9 7.4 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Dynamin_N PF00350.23 EON97208.1 - 1.1e-23 84.1 0.0 5.9e-23 81.8 0.0 2.1 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EON97208.1 - 1e-11 44.6 0.0 1.7e-07 30.8 0.0 2.9 2 1 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EON97208.1 - 0.0027 17.8 0.0 0.033 14.2 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EON97208.1 - 0.073 13.6 0.6 0.22 12.0 0.1 2.1 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 EON97208.1 - 0.084 12.6 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arm_3 PF16186.5 EON97208.1 - 0.086 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Atypical Arm repeat AAA_21 PF13304.6 EON97208.1 - 0.14 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 EON97208.1 - 0.17 11.4 0.0 6 6.4 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF3106 PF11304.8 EON97208.1 - 7.6 7.1 11.7 0.65 10.5 3.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) PhyH PF05721.13 EON97210.1 - 8.3e-14 52.3 0.0 1.1e-13 51.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EON97210.1 - 0.0077 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase NTP_transferase PF00483.23 EON97211.1 - 4e-30 105.2 0.0 5.1e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EON97211.1 - 1.4e-09 37.3 6.4 4e-06 26.3 0.0 3.8 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EON97211.1 - 1e-05 26.0 0.0 1.5e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EON97211.1 - 0.041 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2OG-FeII_Oxy_2 PF13532.6 EON97213.1 - 3.1e-31 109.1 0.0 7.7e-31 107.8 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily IF-2B PF01008.17 EON97214.1 - 7.5e-21 74.6 0.2 4.2e-15 55.7 0.0 2.3 2 1 0 2 2 2 2 Initiation factor 2 subunit family NUDIX PF00293.28 EON97214.1 - 1.2e-09 38.3 0.3 2.7e-09 37.2 0.3 1.5 1 0 0 1 1 1 1 NUDIX domain DUF1870 PF08965.10 EON97214.1 - 0.079 13.0 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) BSP PF04450.12 EON97215.1 - 0.00042 20.2 0.0 0.00073 19.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase of plants and bacteria DUF5106 PF17127.4 EON97215.1 - 0.11 12.8 1.8 2 8.7 1.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5106) PDZ_6 PF17820.1 EON97215.1 - 0.14 12.0 0.1 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 PDZ domain DUF1264 PF06884.11 EON97216.1 - 1.4e-44 151.7 0.5 1.6e-44 151.5 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) ASCH PF04266.14 EON97217.1 - 0.0044 17.6 0.0 0.0067 17.0 0.0 1.3 1 0 0 1 1 1 1 ASCH domain Fe-ADH PF00465.19 EON97218.1 - 4.5e-98 328.4 0.0 5.6e-98 328.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EON97218.1 - 2.6e-15 56.8 0.0 2.7e-12 46.9 0.0 2.3 2 1 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 EON97218.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein DNA_photolyase PF00875.18 EON97218.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 DNA photolyase Fucose_iso_N1 PF07881.12 EON97218.1 - 0.16 11.9 0.1 0.4 10.5 0.1 1.6 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain Sec3_C PF09763.9 EON97219.1 - 1.3e-240 800.6 0.6 1.6e-240 800.3 0.6 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 EON97219.1 - 1.3e-30 105.4 0.0 2.7e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 EON97219.1 - 0.00033 20.9 2.8 0.0014 18.9 0.0 3.3 4 0 0 4 4 4 1 Sec3 exocyst complex subunit L_biotic_typeA PF04604.13 EON97219.1 - 0.053 13.4 0.0 0.21 11.5 0.0 2.0 1 0 0 1 1 1 0 Type-A lantibiotic Vps52 PF04129.12 EON97219.1 - 0.39 9.4 2.9 0.39 9.4 0.3 2.1 2 0 0 2 2 2 0 Vps52 / Sac2 family DUF2433 PF10360.9 EON97220.1 - 1.2e-48 164.3 0.0 1.8e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 EON97220.1 - 0.00025 21.6 0.0 0.00064 20.3 0.0 1.8 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EON97220.1 - 0.011 15.9 0.1 0.027 14.6 0.1 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PRCC PF10253.9 EON97220.1 - 0.18 12.5 10.0 0.42 11.4 10.0 1.6 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting TFIIA PF03153.13 EON97220.1 - 5.7 6.8 7.2 0.69 9.8 3.1 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit K_oxygenase PF13434.6 EON97221.1 - 7.6e-87 291.6 0.0 7.7e-85 285.0 0.0 2.0 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EON97221.1 - 6e-08 32.3 0.0 7.7e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON97221.1 - 2.3e-06 27.1 0.0 0.00018 20.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EON97223.1 - 1.6e-43 148.1 0.1 5.4e-43 146.4 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EON97223.1 - 1.9e-11 43.8 0.0 2.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 EON97223.1 - 0.00014 22.0 0.1 0.00022 21.3 0.1 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 EON97223.1 - 0.00067 19.0 0.1 0.0011 18.3 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 EON97223.1 - 0.0021 18.9 0.0 0.0053 17.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_2 PF03446.15 EON97223.1 - 0.003 17.7 0.1 0.0054 16.9 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EON97223.1 - 0.019 14.5 0.1 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_C PF03720.15 EON97223.1 - 0.08 13.4 0.0 0.4 11.1 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain F420_oxidored PF03807.17 EON97223.1 - 0.11 13.0 0.2 0.22 12.1 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1771 PF08590.10 EON97224.1 - 0.00099 19.4 7.3 0.0029 17.9 7.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.16 EON97224.1 - 0.0014 18.3 0.1 0.0025 17.5 0.1 1.4 1 0 0 1 1 1 1 CUE domain Smr PF01713.21 EON97224.1 - 0.0033 17.8 0.1 0.0095 16.3 0.1 1.7 1 0 0 1 1 1 1 Smr domain Pex19 PF04614.12 EON97224.1 - 0.026 14.3 0.1 0.047 13.5 0.1 1.4 1 0 0 1 1 1 0 Pex19 protein family Acetyltransf_1 PF00583.25 EON97225.1 - 7.2e-09 35.9 0.0 1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON97225.1 - 1.9e-08 34.6 0.0 2.9e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EON97225.1 - 2.4e-07 30.8 0.0 1.4e-06 28.3 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EON97225.1 - 0.00067 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EON97225.1 - 0.0011 19.6 0.0 0.0014 19.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3626 PF12294.8 EON97225.1 - 0.1 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) E1_dh PF00676.20 EON97226.1 - 4.4e-90 301.7 0.0 5.2e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EON97226.1 - 0.00095 19.0 0.0 0.018 14.8 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EON97226.1 - 0.033 13.4 0.0 0.089 12.0 0.0 1.7 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase CAP59_mtransfer PF11735.8 EON97227.1 - 4.8e-57 193.4 0.0 6.1e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 NPC1_N PF16414.5 EON97228.1 - 1.8e-83 279.9 8.4 2.6e-83 279.3 8.4 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 EON97228.1 - 2.2e-73 247.7 16.6 3.2e-72 243.8 16.6 2.1 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 EON97228.1 - 4.1e-51 172.8 4.5 4.1e-51 172.8 4.5 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 EON97228.1 - 7e-07 28.5 28.4 6.2e-05 22.1 6.6 2.5 2 0 0 2 2 2 2 MMPL family Folate_rec PF03024.14 EON97228.1 - 5.2e-06 26.4 3.4 1.1e-05 25.4 3.4 1.5 1 0 0 1 1 1 1 Folate receptor family Sugar_tr PF00083.24 EON97229.1 - 5.6e-74 249.6 21.3 6.6e-74 249.4 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON97229.1 - 6.2e-23 81.3 28.3 6.7e-17 61.4 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2441 PF10386.9 EON97232.1 - 0.12 12.3 0.2 0.15 12.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2441) TPPII_N PF12583.8 EON97234.1 - 1.5 9.4 9.2 2 9.0 9.2 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Na_Ca_ex PF01699.24 EON97235.1 - 2.6e-22 79.4 6.8 3.2e-22 79.1 6.8 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF4079 PF13301.6 EON97235.1 - 0.0045 17.1 2.3 0.0073 16.5 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) MARVEL PF01284.23 EON97235.1 - 0.0047 17.0 1.8 0.0067 16.5 1.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain Tubulin PF00091.25 EON97236.1 - 1.7e-63 214.4 0.0 2.3e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EON97236.1 - 6.3e-45 152.4 0.0 9.6e-45 151.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EON97236.1 - 0.00014 21.6 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF726 PF05277.12 EON97237.1 - 3e-127 424.3 3.8 4.2e-127 423.8 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) CAP_GLY PF01302.25 EON97238.1 - 8.9e-20 70.5 0.1 1.6e-19 69.7 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 EON97238.1 - 1.7e-08 34.6 17.7 0.024 15.1 4.4 5.3 4 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EON97238.1 - 4.3e-07 29.6 16.7 0.00091 18.9 7.4 4.8 3 1 3 6 6 6 4 Leucine rich repeat LRR_6 PF13516.6 EON97238.1 - 9.8e-05 22.1 11.5 1.7 8.9 0.2 5.4 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 EON97238.1 - 0.00059 19.4 1.4 0.36 10.3 0.6 3.0 2 2 1 3 3 3 2 Leucine-rich repeat RNase_HII PF01351.18 EON97238.1 - 0.021 14.7 0.1 0.049 13.5 0.1 1.6 1 0 0 1 1 1 0 Ribonuclease HII LRR_1 PF00560.33 EON97238.1 - 0.24 12.1 10.1 31 5.6 0.0 5.7 6 1 0 6 6 6 0 Leucine Rich Repeat DUF3453 PF11935.8 EON97239.1 - 9.8e-20 71.2 1.3 1.4e-16 60.8 0.2 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF3453) RHH_1 PF01402.21 EON97239.1 - 0.098 12.6 0.4 2.7 8.0 0.0 2.9 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family T-box PF00907.22 EON97239.1 - 0.18 12.0 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 T-box VSP PF03302.13 EON97240.1 - 6.3e-05 22.0 1.4 9.3e-05 21.4 1.4 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Rax2 PF12768.7 EON97240.1 - 0.00077 19.0 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Mid2 PF04478.12 EON97240.1 - 0.036 13.9 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.10 EON97240.1 - 0.037 13.4 0.6 0.095 12.1 0.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TFIIA PF03153.13 EON97240.1 - 8.8 6.2 8.1 19 5.1 8.1 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AA_permease PF00324.21 EON97241.1 - 1.1e-145 485.9 31.7 1.4e-145 485.6 31.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON97241.1 - 1e-38 133.3 33.5 1.3e-38 133.0 33.5 1.1 1 0 0 1 1 1 1 Amino acid permease WTF PF03303.13 EON97241.1 - 0.037 13.8 2.9 0.068 12.9 2.9 1.4 1 0 0 1 1 1 0 WTF protein DUF4781 PF16013.5 EON97241.1 - 0.079 11.8 0.2 0.17 10.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Fungal_trans PF04082.18 EON97242.1 - 2.3e-22 79.3 0.0 3.2e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hamartin PF04388.12 EON97243.1 - 0.18 10.4 14.8 0.19 10.3 14.8 1.1 1 0 0 1 1 1 0 Hamartin protein Nucleo_P87 PF07267.11 EON97243.1 - 5.8 5.7 6.6 6.3 5.5 6.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF948 PF06103.11 EON97244.1 - 0.48 10.7 9.0 8.9 6.7 0.5 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF730 PF05325.11 EON97244.1 - 0.88 9.6 7.1 20 5.2 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF730) DUF3253 PF11625.8 EON97244.1 - 2.8 8.2 11.0 2.6 8.3 3.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3253) Baculo_PEP_C PF04513.12 EON97244.1 - 4.1 7.4 5.7 1.9 8.5 2.2 2.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus P4Ha_N PF08336.11 EON97244.1 - 4.5 7.3 14.6 0.33 11.0 3.6 2.8 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region YtxH PF12732.7 EON97244.1 - 6.2 7.4 10.7 1.8 9.1 0.1 2.9 3 0 0 3 3 3 0 YtxH-like protein PRKCSH-like PF12999.7 EON97244.1 - 7.9 6.2 10.7 0.88 9.3 5.0 2.1 1 1 0 2 2 2 0 Glucosidase II beta subunit-like SHR3_chaperone PF08229.11 EON97245.1 - 7.6e-76 253.3 0.0 8.6e-76 253.1 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 RRM_1 PF00076.22 EON97247.1 - 4.9e-12 45.5 0.0 1.2e-07 31.5 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Flot PF15975.5 EON97247.1 - 0.036 14.3 0.1 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 Flotillin CP12 PF02672.15 EON97247.1 - 0.31 11.8 4.4 0.94 10.3 4.4 1.8 1 0 0 1 1 1 0 CP12 domain CDC45 PF02724.14 EON97247.1 - 6.1 5.0 17.1 10 4.3 17.1 1.4 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EON97247.1 - 6.2 5.2 10.9 10 4.5 10.9 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MaoC_dehydratas PF01575.19 EON97248.1 - 6.8e-22 77.3 0.0 1e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EON97248.1 - 0.014 15.5 0.0 0.47 10.6 0.0 2.4 2 1 0 2 2 2 0 N-terminal half of MaoC dehydratase Sds3 PF08598.11 EON97249.1 - 4.1e-18 66.2 6.1 4.1e-18 66.2 6.1 3.6 2 2 0 2 2 2 1 Sds3-like SpoIIE PF07228.12 EON97250.1 - 0.00028 20.9 0.0 0.0021 18.0 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EON97250.1 - 0.0012 18.5 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C APOC4 PF15119.6 EON97250.1 - 0.095 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein C4 PP2C PF00481.21 EON97250.1 - 0.18 11.4 0.0 1.8 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein phosphatase 2C Serglycin PF04360.12 EON97251.1 - 0.052 13.5 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Serglycin Flot PF15975.5 EON97251.1 - 0.063 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Flotillin ATG101 PF07855.12 EON97251.1 - 0.1 12.6 0.5 1.7 8.6 0.2 2.4 2 0 0 2 2 2 0 Autophagy-related protein 101 Presenilin PF01080.17 EON97252.1 - 4.2 6.0 6.1 3 6.5 0.7 2.1 2 0 0 2 2 2 0 Presenilin HAMP PF00672.25 EON97255.1 - 9.8e-42 141.1 16.7 7.1e-08 32.7 0.2 7.9 6 1 1 7 7 7 6 HAMP domain HATPase_c PF02518.26 EON97255.1 - 8.9e-32 109.9 0.1 3.4e-31 108.0 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EON97255.1 - 1.3e-27 96.2 1.8 8.3e-27 93.6 1.0 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EON97255.1 - 2e-16 59.7 3.9 5.7e-16 58.3 0.6 3.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Syntaxin_2 PF14523.6 EON97255.1 - 5.5e-07 29.9 15.9 3 8.3 0.0 7.8 4 3 2 7 7 6 4 Syntaxin-like protein DUF948 PF06103.11 EON97255.1 - 0.00015 22.0 44.2 0.22 11.8 0.5 9.2 4 1 2 6 6 6 2 Bacterial protein of unknown function (DUF948) DUF4279 PF14106.6 EON97255.1 - 0.00089 19.4 0.0 17 5.6 0.0 5.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4279) Fib_alpha PF08702.10 EON97255.1 - 0.0034 17.6 28.8 0.056 13.6 0.7 6.6 6 1 0 6 6 6 2 Fibrinogen alpha/beta chain family DUF3829 PF12889.7 EON97255.1 - 0.011 15.2 10.0 0.63 9.5 0.1 4.6 4 2 1 5 5 5 0 Protein of unknown function (DUF3829) DUF4795 PF16043.5 EON97255.1 - 0.036 13.7 26.0 0.02 14.5 1.3 5.7 1 1 3 5 5 5 0 Domain of unknown function (DUF4795) GhoS PF11080.8 EON97255.1 - 0.079 12.9 2.2 2.4 8.2 0.0 3.7 3 0 0 3 3 3 0 Endoribonuclease GhoS BORCS6 PF10157.9 EON97255.1 - 0.26 11.5 8.6 14 5.9 0.1 5.2 3 2 2 5 5 5 0 BLOC-1-related complex sub-unit 6 GLE1 PF07817.13 EON97255.1 - 0.64 9.2 12.7 12 5.0 0.0 4.9 3 1 3 6 6 6 0 GLE1-like protein Chitin_bind_4 PF00379.23 EON97256.1 - 0.079 13.5 0.1 0.18 12.4 0.1 1.5 1 0 0 1 1 1 0 Insect cuticle protein ATP-synt_E PF05680.12 EON97257.1 - 1.2e-25 89.6 0.5 1.3e-25 89.5 0.5 1.0 1 0 0 1 1 1 1 ATP synthase E chain DUF1542 PF07564.11 EON97257.1 - 0.031 14.4 3.6 0.05 13.7 3.6 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1542) Drf_GBD PF06371.13 EON97257.1 - 0.096 12.2 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain adh_short PF00106.25 EON97258.1 - 2.8e-22 79.2 0.0 4.6e-21 75.2 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON97258.1 - 4.1e-18 65.8 0.4 4.3e-09 36.3 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EON97258.1 - 0.00079 19.0 0.3 0.017 14.6 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EON97258.1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 EON97258.1 - 0.024 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding KR PF08659.10 EON97258.1 - 0.06 13.3 0.0 0.12 12.2 0.0 1.5 2 0 0 2 2 2 0 KR domain SnoaL PF07366.12 EON97259.1 - 8.7e-24 83.7 0.0 1e-16 60.9 0.0 2.5 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EON97259.1 - 2.6e-16 60.1 0.1 1.5e-11 44.8 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like domain Aldo_ket_red PF00248.21 EON97260.1 - 1.7e-53 181.7 0.0 2.1e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.32 EON97261.1 - 3.7e-14 52.9 9.6 0.011 16.6 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON97261.1 - 6.1e-07 29.6 0.3 0.0025 18.1 0.2 3.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EON97261.1 - 8e-06 24.8 4.7 9e-05 21.3 2.2 3.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EON97261.1 - 0.14 10.8 0.1 9.1 4.9 0.0 2.9 2 1 0 2 2 2 0 Nup133 N terminal like HET PF06985.11 EON97262.1 - 3.5e-14 53.4 0.0 7.1e-12 45.9 0.0 2.5 1 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) SnoaL PF07366.12 EON97263.1 - 0.00023 21.0 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EON97263.1 - 0.078 13.6 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain Pkinase PF00069.25 EON97264.1 - 2.5e-47 161.5 0.0 3.9e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON97264.1 - 2.7e-26 92.4 0.0 4.3e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EON97264.1 - 1.1e-09 38.5 0.0 2.3e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 EON97264.1 - 0.0039 16.6 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yop-YscD_cpl PF16697.5 EON97264.1 - 0.0045 17.3 0.0 0.0099 16.2 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 EON97264.1 - 0.025 13.3 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EON97264.1 - 0.041 13.8 0.0 4.9 7.0 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EON97264.1 - 0.38 9.7 3.9 2.7 6.9 3.9 2.0 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-C2H2 PF00096.26 EON97265.1 - 0.0078 16.6 2.7 0.0078 16.6 2.7 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 EON97265.1 - 0.038 13.8 0.4 0.038 13.8 0.4 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain WD40 PF00400.32 EON97266.1 - 1.8e-08 34.8 6.5 0.4 11.6 0.9 6.6 6 1 0 6 6 6 3 WD domain, G-beta repeat SnoaL_2 PF12680.7 EON97267.1 - 0.038 14.6 0.0 0.093 13.4 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain Cupin_2 PF07883.11 EON97268.1 - 3.4e-08 33.1 0.0 4.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EON97268.1 - 0.0021 18.0 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 EON97268.1 - 0.043 13.5 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 EON97268.1 - 0.046 13.6 0.0 0.057 13.3 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase HMGL-like PF00682.19 EON97269.1 - 0.043 13.4 0.1 0.071 12.7 0.1 1.3 1 0 0 1 1 1 0 HMGL-like HpcH_HpaI PF03328.14 EON97270.1 - 5.4e-34 117.2 0.0 1.1e-33 116.3 0.0 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EON97270.1 - 1.8e-11 43.8 0.0 2.3e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Coiled-coil_56 PF09813.9 EON97271.1 - 3.8e-05 23.7 0.0 3.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 TPR_12 PF13424.6 EON97272.1 - 0.0002 21.6 1.8 0.00035 20.8 0.9 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat T2SSF PF00482.23 EON97272.1 - 0.067 13.1 0.1 0.12 12.3 0.1 1.4 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F TPR_14 PF13428.6 EON97272.1 - 1.1 10.3 5.7 3.2 8.8 3.7 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.22 EON97273.1 - 7.4e-08 32.1 0.0 1.6e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EON97273.1 - 3.7e-05 23.3 0.0 5.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 EON97273.1 - 0.0057 16.4 0.4 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 Calcipressin ChaC PF04752.12 EON97274.1 - 6.4e-33 114.3 0.0 8.8e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Cys_Met_Meta_PP PF01053.20 EON97275.1 - 1.9e-58 197.8 0.0 3.5e-58 197.0 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EON97275.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II RTA1 PF04479.13 EON97276.1 - 4.4e-64 215.9 17.1 4.4e-64 215.9 17.1 1.9 2 0 0 2 2 2 1 RTA1 like protein Caveolin PF01146.17 EON97276.1 - 0.62 10.0 5.0 0.71 9.8 0.6 2.6 2 0 0 2 2 2 0 Caveolin Hep_59 PF07052.11 EON97277.1 - 1.8e-07 31.8 0.1 1.8e-07 31.8 0.1 2.4 2 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 HisG PF01634.18 EON97278.1 - 1.4e-55 187.6 0.1 2.4e-55 186.9 0.1 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EON97278.1 - 7.2e-29 99.7 0.1 1.7e-28 98.6 0.1 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain DUF3837 PF12939.7 EON97278.1 - 0.045 14.2 0.0 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) NMT1 PF09084.11 EON97278.1 - 0.15 12.0 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 NMT1/THI5 like KDZ PF18758.1 EON97278.1 - 0.19 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase PRIMA1 PF16101.5 EON97279.1 - 0.82 9.7 4.6 1.4 9.0 4.6 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TMEM154 PF15102.6 EON97280.1 - 0.0007 19.5 0.9 0.0013 18.7 0.9 1.4 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.11 EON97280.1 - 0.0071 16.5 2.1 0.014 15.5 2.1 1.5 1 0 0 1 1 1 1 Podoplanin TMEM51 PF15345.6 EON97280.1 - 0.023 14.6 0.1 0.042 13.7 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 DUF5305 PF17231.2 EON97280.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5305) EphA2_TM PF14575.6 EON97280.1 - 0.1 13.5 0.0 0.24 12.3 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 EON97280.1 - 0.1 12.0 1.6 0.24 10.9 1.6 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Granulin PF00396.18 EON97280.1 - 0.16 12.4 30.9 1.4 9.3 5.9 3.8 2 1 1 3 3 3 0 Granulin DAP10 PF07213.11 EON97280.1 - 0.23 11.4 2.1 0.27 11.2 0.6 1.9 2 0 0 2 2 2 0 DAP10 membrane protein Lustrin_cystein PF14625.6 EON97280.1 - 3.5 8.1 25.4 0.7 10.3 2.7 3.7 3 1 0 3 3 3 0 Lustrin, cysteine-rich repeated domain WD40 PF00400.32 EON97281.1 - 1e-16 61.0 11.3 0.0023 18.7 0.2 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON97281.1 - 1.3e-06 28.6 0.0 0.025 14.9 0.0 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EON97281.1 - 0.0013 18.6 0.0 1.4 8.9 0.0 3.3 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat adh_short_C2 PF13561.6 EON97282.1 - 3.1e-49 167.6 0.0 3.5e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON97282.1 - 2e-35 122.0 0.0 2.5e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON97282.1 - 4.8e-10 39.6 0.0 7.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Avian_gp85 PF03708.14 EON97282.1 - 0.18 11.0 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Avian retrovirus envelope protein, gp85 Polysacc_deac_1 PF01522.21 EON97283.1 - 1.7e-25 89.3 0.0 2.8e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 EON97283.1 - 0.0015 17.8 0.0 0.0036 16.5 0.0 1.6 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase GFRP PF06399.13 EON97283.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Fcf1 PF04900.12 EON97284.1 - 1.8e-34 118.1 0.1 3.6e-34 117.1 0.1 1.5 1 0 0 1 1 1 1 Fcf1 YL1 PF05764.13 EON97284.1 - 0.29 11.2 24.2 0.4 10.8 24.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Dicty_REP PF05086.12 EON97284.1 - 5.8 4.8 6.4 6 4.7 6.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDC45 PF02724.14 EON97284.1 - 9.1 4.4 15.5 12 4.0 15.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Cnd2 PF05786.14 EON97285.1 - 0 1036.7 4.3 0 1036.4 4.3 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EON97285.1 - 0.01 16.1 2.7 0.011 16.0 0.0 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal SDA1 PF05285.12 EON97285.1 - 0.22 10.9 10.1 0.44 9.9 10.1 1.5 1 0 0 1 1 1 0 SDA1 zf-RING_2 PF13639.6 EON97286.1 - 0.00087 19.6 7.1 0.00087 19.6 7.1 2.8 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 EON97286.1 - 0.011 15.6 6.6 0.011 15.6 6.6 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Rhodanese_C PF12368.8 EON97286.1 - 0.42 11.0 12.8 1.9 8.9 1.0 2.6 2 1 0 2 2 2 0 Rhodanase C-terminal zf-C3HC4_3 PF13920.6 EON97286.1 - 1 9.3 18.3 0.17 11.8 4.9 2.8 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 EON97286.1 - 3.9 7.7 17.1 9.5 6.4 5.6 2.5 1 1 1 2 2 2 0 Zinc-binding RING-finger MGC-24 PF05283.11 EON97287.1 - 0.54 10.7 13.9 0.79 10.2 13.9 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Sporozoite_P67 PF05642.11 EON97287.1 - 0.77 7.8 9.2 0.88 7.6 9.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GASA PF02704.14 EON97287.1 - 4.2 7.6 9.6 6.7 6.9 9.6 1.3 1 0 0 1 1 1 0 Gibberellin regulated protein STT3 PF02516.14 EON97288.1 - 2.6e-144 481.8 31.1 1.7e-139 465.9 28.9 2.2 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit MadM PF03818.13 EON97288.1 - 0.013 15.4 1.6 0.67 9.9 0.2 3.0 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit Aldo_ket_red PF00248.21 EON97289.1 - 4.8e-60 203.2 0.0 5.8e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2187 PF09953.9 EON97289.1 - 0.11 12.6 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) PI-PLC-X PF00388.19 EON97290.1 - 1.1e-09 38.1 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain HA2 PF04408.23 EON97291.1 - 1.2e-20 73.8 0.0 1.2e-20 73.8 0.0 3.3 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EON97291.1 - 2.6e-17 63.0 0.0 1.3e-16 60.7 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EON97291.1 - 3.2e-13 50.0 0.0 8.3e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EON97291.1 - 1.1e-07 31.8 0.0 2.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EON97291.1 - 5.4e-05 23.5 0.1 0.00016 22.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EON97291.1 - 7.8e-05 22.1 0.0 0.00018 20.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EON97291.1 - 0.00082 19.7 0.1 0.0021 18.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON97291.1 - 0.00096 18.9 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EON97291.1 - 0.0025 17.8 0.0 0.84 9.6 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EON97291.1 - 0.0027 16.8 0.0 0.0073 15.4 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 EON97291.1 - 0.011 15.4 0.2 0.03 13.9 0.2 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 EON97291.1 - 0.026 14.5 0.1 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_7 PF12775.7 EON97291.1 - 0.035 13.6 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EON97291.1 - 0.042 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 EON97291.1 - 0.044 13.8 0.1 0.26 11.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EON97291.1 - 0.05 13.8 0.7 0.3 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EON97291.1 - 0.085 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 EON97291.1 - 0.093 13.3 0.0 0.32 11.5 0.0 1.9 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 EON97291.1 - 0.12 12.0 0.1 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RRM_1 PF00076.22 EON97292.1 - 5.3e-23 80.6 0.1 6.8e-23 80.3 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EON97292.1 - 0.0016 18.5 0.0 0.0032 17.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 EON97292.1 - 0.043 13.7 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif PH PF00169.29 EON97293.1 - 9.9e-09 35.7 1.0 2.1e-07 31.4 0.0 2.6 2 1 0 2 2 2 1 PH domain PH_9 PF15410.6 EON97293.1 - 0.00037 20.9 0.0 0.00089 19.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DUF846 PF05832.12 EON97295.1 - 2.2e-51 173.6 4.5 2.7e-51 173.3 4.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Glyco_hydro_47 PF01532.20 EON97296.1 - 1.2e-169 565.1 0.2 1.5e-169 564.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Fungal_trans_2 PF11951.8 EON97297.1 - 1.6e-88 297.2 0.0 1.9e-88 296.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2613 PF11021.8 EON97298.1 - 0.018 15.1 0.4 0.033 14.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) ANTH PF07651.16 EON97299.1 - 0.11 11.5 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 ANTH domain Abhydrolase_1 PF00561.20 EON97301.1 - 1.1e-21 77.6 0.1 3.8e-21 75.9 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON97301.1 - 1e-16 62.2 0.0 1.5e-16 61.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON97301.1 - 1.9e-14 53.5 0.0 7.7e-14 51.5 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 EON97301.1 - 3.1e-06 26.4 0.0 5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.20 EON97301.1 - 0.00012 22.3 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.21 EON97301.1 - 0.00037 20.0 0.0 0.0081 15.7 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ndr PF03096.14 EON97301.1 - 0.0048 15.6 0.0 0.17 10.6 0.0 2.1 2 0 0 2 2 2 1 Ndr family DLH PF01738.18 EON97301.1 - 0.0089 15.6 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase PF07224.11 EON97301.1 - 0.05 12.6 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Esterase PF00756.20 EON97301.1 - 0.052 13.2 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Peptidase_S10 PF00450.22 EON97301.1 - 0.19 11.1 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase Pyr_redox_3 PF13738.6 EON97304.1 - 3.8e-18 65.8 0.0 1.4e-16 60.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON97304.1 - 3.2e-14 52.8 0.0 1.8e-11 43.8 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 EON97304.1 - 8.4e-13 47.6 0.0 3.4e-10 39.0 0.0 2.9 3 1 0 4 4 4 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EON97304.1 - 1.2e-12 47.7 0.0 1.6e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON97304.1 - 2.9e-05 24.2 0.0 0.00011 22.3 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EON97304.1 - 3.1e-05 24.0 0.6 0.016 15.2 0.2 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EON97304.1 - 8.6e-05 22.3 0.0 0.066 12.8 0.0 3.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 EON97304.1 - 0.00017 20.9 0.4 0.00047 19.5 0.0 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EON97304.1 - 0.011 14.5 0.1 0.55 8.9 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox PF00070.27 EON97304.1 - 0.026 15.1 1.7 3.1 8.4 0.4 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON97304.1 - 0.056 12.5 0.1 9.9 5.1 0.0 3.2 4 0 0 4 4 4 0 Glucose inhibited division protein A HTH_32 PF13565.6 EON97305.1 - 0.22 12.1 2.7 4.8 7.9 0.1 3.0 2 0 0 2 2 2 0 Homeodomain-like domain EF-hand_1 PF00036.32 EON97306.1 - 1.1e-25 87.1 8.9 2.7e-06 26.5 0.0 5.4 5 1 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 EON97306.1 - 3.1e-21 73.4 7.9 4e-05 23.2 0.1 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 EON97306.1 - 3.1e-21 75.6 6.7 5.8e-08 33.1 0.0 3.9 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EON97306.1 - 4.7e-19 68.0 10.4 1.2e-09 37.8 0.0 4.4 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 EON97306.1 - 9e-16 56.6 5.4 4.3e-05 22.8 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EON97306.1 - 0.091 13.1 2.0 0.7 10.3 0.0 3.2 4 0 0 4 4 4 0 EF-hand domain GUN4 PF05419.12 EON97306.1 - 0.13 12.4 0.0 0.86 9.7 0.0 1.9 2 0 0 2 2 2 0 GUN4-like EAP30 PF04157.16 EON97306.1 - 0.21 10.8 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family Sod_Fe_C PF02777.18 EON97307.1 - 1.1e-12 48.0 0.0 1.6e-05 25.0 0.0 2.3 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Rota_Capsid_VP6 PF00980.17 EON97307.1 - 0.2 10.6 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Rotavirus major capsid protein VP6 Sugar_tr PF00083.24 EON97308.1 - 2.4e-52 178.3 4.9 2.7e-52 178.1 4.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON97308.1 - 7.3e-05 21.8 21.2 0.00016 20.7 20.0 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3021 PF11457.8 EON97308.1 - 0.71 10.2 14.2 0.83 10.0 13.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) ADH_zinc_N PF00107.26 EON97309.1 - 2.4e-17 63.1 0.6 5.7e-16 58.7 0.0 2.5 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON97309.1 - 6.3e-14 51.8 11.0 5.8e-13 48.7 8.5 2.6 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 EON97309.1 - 0.00028 20.3 0.1 0.00047 19.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EON97309.1 - 0.049 12.9 0.1 0.082 12.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short_C2 PF13561.6 EON97310.1 - 7.1e-29 101.0 0.1 3.8e-23 82.3 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON97310.1 - 1.6e-28 99.6 0.0 2e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON97310.1 - 0.00019 21.4 0.1 0.00032 20.6 0.1 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 EON97311.1 - 1.1e-14 54.5 0.1 1.6e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON97311.1 - 6.7e-12 45.3 0.4 3.3e-11 43.0 0.6 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EON97311.1 - 1e-06 28.4 0.3 5.3e-06 26.1 0.2 2.0 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 EON97311.1 - 0.0089 15.3 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EON97311.1 - 0.025 14.8 0.2 0.043 14.1 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain Pilus_CpaD PF09476.10 EON97311.1 - 0.032 14.0 0.1 0.05 13.3 0.1 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) ADH_zinc_N_2 PF13602.6 EON97311.1 - 0.066 14.3 0.0 0.13 13.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 EON97311.1 - 0.14 11.7 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FMO-like PF00743.19 EON97312.1 - 2.4e-26 92.3 0.0 1.4e-23 83.2 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EON97312.1 - 1.2e-21 77.3 0.0 3.7e-20 72.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EON97312.1 - 1.1e-18 67.5 0.0 1.5e-15 57.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON97312.1 - 8.8e-14 51.4 0.0 2.3e-08 33.6 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EON97312.1 - 1.9e-07 31.5 0.1 0.027 15.0 0.1 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EON97312.1 - 3.3e-07 29.9 0.1 0.0015 17.9 0.1 3.1 2 1 1 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.19 EON97312.1 - 1.5e-06 27.7 0.1 0.024 14.0 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EON97312.1 - 2.6e-06 27.6 0.0 0.00021 21.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EON97312.1 - 7.9e-06 25.9 0.6 0.48 10.4 0.0 3.8 3 1 1 4 4 4 2 FAD-NAD(P)-binding HI0933_like PF03486.14 EON97312.1 - 2.2e-05 23.4 0.1 0.0037 16.0 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 EON97312.1 - 6.3e-05 22.2 0.0 0.13 11.4 0.0 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A Shikimate_DH PF01488.20 EON97312.1 - 0.00023 21.3 0.1 0.72 9.9 0.0 3.0 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EON97312.1 - 0.0003 21.0 1.0 0.046 14.0 0.0 3.0 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_7 PF13241.6 EON97312.1 - 0.00045 20.6 0.0 0.08 13.4 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EON97312.1 - 0.00059 19.2 0.0 0.093 12.0 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EON97312.1 - 0.00062 19.7 0.1 0.27 11.1 0.1 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 EON97312.1 - 0.0007 19.2 0.2 0.016 14.8 0.1 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_2 PF00890.24 EON97312.1 - 0.0026 16.9 0.0 0.044 12.9 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EON97312.1 - 0.005 15.9 0.0 0.53 9.3 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein F420_oxidored PF03807.17 EON97312.1 - 0.0063 17.1 0.0 28 5.4 0.0 3.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EON97312.1 - 0.0066 16.1 0.0 2.1 8.0 0.0 2.6 2 1 1 3 3 3 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 EON97312.1 - 0.011 15.9 0.1 4.5 7.4 0.0 2.4 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Thi4 PF01946.17 EON97312.1 - 0.036 13.3 0.2 3.1 7.0 0.0 3.2 4 0 0 4 4 4 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 EON97312.1 - 0.037 13.6 0.2 0.37 10.3 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF498 PF04430.14 EON97312.1 - 0.04 14.0 0.0 0.69 10.0 0.0 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF498/DUF598) ELFV_dehydrog PF00208.21 EON97312.1 - 0.05 13.3 0.2 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DAO PF01266.24 EON97312.1 - 0.061 12.9 0.0 0.75 9.3 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase SnoaL_2 PF12680.7 EON97312.1 - 0.064 13.9 1.2 0.43 11.2 0.0 2.6 3 0 0 3 3 2 0 SnoaL-like domain NAD_Gly3P_dh_N PF01210.23 EON97312.1 - 0.16 12.0 0.1 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.21 EON97312.1 - 0.16 11.3 0.0 21 4.4 0.0 2.3 2 0 0 2 2 2 0 ThiF family Collagen PF01391.18 EON97312.1 - 2.4 8.0 7.9 0.29 10.9 3.1 1.9 2 0 0 2 2 1 0 Collagen triple helix repeat (20 copies) ADH_zinc_N PF00107.26 EON97313.1 - 2.4e-28 98.7 0.5 4.9e-28 97.7 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON97313.1 - 5.1e-17 63.2 0.0 3.4e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON97313.1 - 3.7e-05 23.6 0.1 0.00014 21.8 0.1 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EON97313.1 - 0.0013 18.1 0.1 0.002 17.5 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EON97313.1 - 0.0031 17.8 0.0 0.006 16.8 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.21 EON97313.1 - 0.008 15.9 0.1 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 EON97313.1 - 0.038 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldolase_II PF00596.21 EON97314.1 - 2.7e-48 164.4 0.5 3.5e-48 164.0 0.5 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain zf-MYND PF01753.18 EON97315.1 - 1e-10 41.5 12.5 1.7e-10 40.8 12.5 1.4 1 0 0 1 1 1 1 MYND finger Acetyltransf_9 PF13527.7 EON97316.1 - 0.027 14.6 0.1 0.07 13.2 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PDCD2_C PF04194.13 EON97317.1 - 8e-48 162.8 0.4 2.5e-46 157.9 0.0 2.5 3 0 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain zf-C2H2 PF00096.26 EON97318.1 - 2.2e-10 40.4 17.6 9.2e-05 22.7 5.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EON97318.1 - 1.2e-07 31.8 11.3 0.0011 19.3 1.9 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EON97318.1 - 3.6e-06 27.4 15.4 0.033 15.0 4.3 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EON97318.1 - 0.00046 19.9 6.3 0.01 15.6 1.1 2.5 2 0 0 2 2 2 2 zinc-finger C2H2-type EspB_PE PF18625.1 EON97318.1 - 0.23 12.0 0.4 0.47 11.0 0.4 1.5 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain zf-UBR PF02207.20 EON97318.1 - 0.88 9.8 5.9 1.7 8.8 5.9 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) AT_hook PF02178.19 EON97318.1 - 0.96 9.5 5.2 2.9 8.1 5.2 1.9 1 0 0 1 1 1 0 AT hook motif C1_4 PF07975.12 EON97318.1 - 1.4 9.2 5.5 3 8.2 5.5 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_6 PF13912.6 EON97318.1 - 2.7 8.1 8.1 5.4 7.1 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 EON97318.1 - 9.4 6.2 8.5 97 3.0 8.5 2.4 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Peptidase_S8 PF00082.22 EON97319.1 - 2.7e-39 135.2 3.5 1.8e-21 76.7 0.7 2.2 1 1 1 2 2 2 2 Subtilase family CBS PF00571.28 EON97320.1 - 4e-34 116.9 6.8 4.8e-09 36.5 0.0 5.4 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 EON97320.1 - 1.3e-08 34.7 0.1 5.6e-08 32.6 0.0 2.2 2 1 0 2 2 2 1 PB1 domain Alpha-mann_mid PF09261.11 EON97320.1 - 0.15 12.2 1.6 0.36 11.0 0.2 2.3 2 1 0 2 2 2 0 Alpha mannosidase middle domain FMN_dh PF01070.18 EON97321.1 - 5.8e-121 403.8 0.0 6.8e-121 403.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EON97321.1 - 1.6e-05 24.1 0.1 6.8e-05 22.0 0.0 1.9 1 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 EON97321.1 - 3.3e-05 23.3 0.0 0.39 10.0 0.0 3.1 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 EON97321.1 - 0.00091 18.5 0.0 0.0018 17.5 0.0 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EON97321.1 - 0.0015 18.1 0.1 0.1 12.1 0.0 2.9 3 1 0 4 4 4 1 Histidine biosynthesis protein Bac_luciferase PF00296.20 EON97321.1 - 0.0073 15.8 0.1 0.72 9.2 0.1 2.3 2 0 0 2 2 2 2 Luciferase-like monooxygenase Glyco_transf_20 PF00982.21 EON97322.1 - 8.8e-150 499.5 0.0 1.2e-149 499.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EON97322.1 - 3.7e-70 235.7 0.0 1.1e-69 234.2 0.0 1.8 2 0 0 2 2 2 1 Trehalose-phosphatase VID27 PF08553.10 EON97323.1 - 3.7e-192 638.1 0.1 5.2e-192 637.6 0.1 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EON97323.1 - 8.3e-77 256.9 0.5 8.3e-77 256.9 0.5 2.4 2 0 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 EON97323.1 - 2.5e-44 150.0 1.4 4.4e-44 149.2 0.6 1.8 2 0 0 2 2 2 1 VID27 PH-like domain RasGAP PF00616.19 EON97324.1 - 8.7e-60 202.0 0.1 4.7e-59 199.6 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EON97324.1 - 3.9e-29 101.5 6.5 3.9e-29 101.5 6.5 2.5 2 0 0 2 2 2 1 RasGAP C-terminus DNA_ligase_A_M PF01068.21 EON97325.1 - 4.8e-50 170.0 0.2 5.1e-48 163.4 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EON97325.1 - 3.9e-35 121.7 0.0 1.1e-34 120.2 0.0 1.8 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EON97325.1 - 1e-19 70.9 0.0 3.2e-19 69.3 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EON97325.1 - 7.7e-05 23.1 0.0 0.00018 21.8 0.0 1.6 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 EON97325.1 - 0.0075 16.1 0.7 4 7.2 0.0 2.6 2 1 1 3 3 3 2 mRNA capping enzyme, catalytic domain Adaptin_N PF01602.20 EON97326.1 - 2.3e-138 462.0 2.7 3.2e-138 461.6 2.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EON97326.1 - 1e-63 214.2 1.7 6.4e-61 205.1 0.1 2.7 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EON97326.1 - 1.7e-17 63.5 0.1 5.2e-08 33.2 0.0 4.9 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.22 EON97326.1 - 4e-10 39.1 6.3 0.023 14.9 0.0 6.6 9 0 0 9 9 8 2 HEAT repeat HEAT_EZ PF13513.6 EON97326.1 - 7e-05 23.2 0.1 0.64 10.6 0.0 4.7 3 1 1 4 4 4 1 HEAT-like repeat UNC45-central PF11701.8 EON97326.1 - 7.5e-05 22.7 1.1 0.04 13.9 0.0 2.8 3 0 0 3 3 3 2 Myosin-binding striated muscle assembly central RIX1 PF08167.12 EON97326.1 - 0.015 15.0 0.1 9.6 5.9 0.0 3.1 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis Arm PF00514.23 EON97326.1 - 0.018 15.0 0.7 16 5.7 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EON97326.1 - 0.035 14.1 0.1 2.6 8.1 0.0 3.1 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.8 EON97326.1 - 0.051 13.1 0.1 2.2 7.8 0.0 3.1 2 1 1 3 3 3 0 CLASP N terminal RTP1_C1 PF10363.9 EON97326.1 - 0.081 13.1 0.3 5.1 7.3 0.0 3.7 2 2 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Pyr_redox_3 PF13738.6 EON97327.1 - 9.3e-16 57.9 0.0 3.5e-15 56.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EON97327.1 - 1.5e-11 43.4 0.0 4.6e-11 41.8 0.0 1.7 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EON97327.1 - 1.9e-11 43.7 0.0 6.5e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EON97327.1 - 5.4e-06 25.9 0.0 9.2e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON97327.1 - 9.6e-05 22.5 0.0 0.00027 21.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EON97327.1 - 0.0011 18.9 0.2 0.021 14.8 0.2 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 EON97327.1 - 0.0045 16.3 0.1 0.0097 15.2 0.0 1.6 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EON97327.1 - 0.0063 16.1 0.0 3.6 7.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EON97327.1 - 0.014 14.2 0.1 2 7.0 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 EON97327.1 - 0.11 11.5 0.1 8.3 5.4 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Glyco_hydro_106 PF17132.4 EON97328.1 - 8.7e-36 123.5 4.5 6.4e-27 94.2 0.2 2.3 1 1 1 2 2 2 2 alpha-L-rhamnosidase Glyco_hydro_2_N PF02837.18 EON97328.1 - 0.0021 18.0 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain RPAP1_C PF08620.10 EON97329.1 - 1.2e-26 92.6 0.0 1.9e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EON97329.1 - 9.3e-20 70.1 2.8 2e-19 69.1 2.8 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal HEAT PF02985.22 EON97329.1 - 0.056 13.7 0.1 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 HEAT repeat DUF1996 PF09362.10 EON97330.1 - 9.6e-59 199.2 0.2 1.6e-58 198.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HUN PF08729.10 EON97331.1 - 1.4e-07 31.3 0.6 2.7e-07 30.5 0.6 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain zf-H2C2 PF09337.10 EON97332.1 - 2e-10 40.7 0.8 4.1e-10 39.7 0.8 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 EON97332.1 - 2.3e-06 27.6 0.3 4.2e-06 26.8 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_4 PF13420.7 EON97332.1 - 2.5e-05 24.5 0.0 4.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON97332.1 - 0.0003 21.0 0.0 0.00054 20.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EON97332.1 - 0.0091 16.7 0.0 0.029 15.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Alpha-amylase PF00128.24 EON97333.1 - 4.8e-76 256.5 0.0 7.9e-76 255.8 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EON97333.1 - 0.0063 16.6 0.0 0.05 13.7 0.0 2.4 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain Glyco_transf_20 PF00982.21 EON97334.1 - 4.5e-198 658.7 0.0 5.2e-198 658.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 EON97334.1 - 0.0011 19.4 0.0 0.0023 18.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 CSN8_PSD8_EIF3K PF10075.9 EON97335.1 - 1.2e-42 145.3 0.1 1.7e-42 144.8 0.1 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Sugar_tr PF00083.24 EON97336.1 - 5.6e-101 338.6 18.6 6.4e-101 338.4 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON97336.1 - 2.8e-22 79.1 25.0 5.3e-19 68.3 7.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EON97336.1 - 0.0022 16.5 0.5 0.0022 16.5 0.5 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) EBP PF05241.12 EON97336.1 - 0.034 13.6 8.8 1.3 8.5 2.6 2.4 2 0 0 2 2 2 0 Emopamil binding protein Sugar_tr PF00083.24 EON97337.1 - 3.7e-78 263.4 15.7 4.2e-78 263.2 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Phage_holin_6_1 PF09682.10 EON97337.1 - 0.54 10.7 3.8 6.1 7.3 0.0 3.1 3 0 0 3 3 3 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Cpn60_TCP1 PF00118.24 EON97338.1 - 3e-163 544.0 0.6 3.4e-163 543.8 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 EON97338.1 - 0.029 12.9 0.0 0.043 12.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Cpn60_TCP1 PF00118.24 EON97339.1 - 2.5e-153 511.3 6.9 2.9e-153 511.1 6.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 EON97339.1 - 0.033 13.4 0.3 0.08 12.2 0.3 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PNTB_4TM PF12769.7 EON97339.1 - 0.13 12.7 0.2 0.54 10.8 0.0 2.1 3 0 0 3 3 3 0 4TM region of pyridine nucleotide transhydrogenase, mitoch GNAT_acetyltran PF12746.7 EON97339.1 - 0.24 10.9 2.6 0.15 11.6 0.2 1.8 2 0 0 2 2 2 0 GNAT acetyltransferase DEK_C PF08766.11 EON97340.1 - 0.00034 20.5 0.1 0.0016 18.3 0.0 2.2 2 0 0 2 2 2 1 DEK C terminal domain Peptidase_M57 PF12388.8 EON97341.1 - 2.6e-07 30.5 0.0 3.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_5 PF13688.6 EON97341.1 - 2.8e-06 27.6 0.2 3.9e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 EON97341.1 - 3e-05 23.9 0.2 6e-05 22.9 0.2 1.5 1 1 0 1 1 1 1 Matrixin Peptidase_M43 PF05572.13 EON97341.1 - 5.3e-05 23.2 0.2 7.8e-05 22.6 0.2 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.6 EON97341.1 - 0.00018 21.5 0.1 0.00023 21.1 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EON97341.1 - 0.00037 21.0 0.2 0.00055 20.4 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EON97341.1 - 0.00066 19.4 0.0 0.00095 18.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 EON97341.1 - 0.0037 17.4 0.0 0.0087 16.2 0.0 1.6 1 1 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family DUF4953 PF16313.5 EON97341.1 - 0.0048 16.2 0.0 0.0076 15.5 0.0 1.2 1 0 0 1 1 1 1 Met-zincin Peptidase_M66 PF10462.9 EON97341.1 - 0.096 11.6 0.7 0.15 11.0 0.7 1.2 1 0 0 1 1 1 0 Peptidase M66 Zincin_1 PF06262.11 EON97341.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Zincin-like metallopeptidase Astacin PF01400.24 EON97341.1 - 0.19 11.3 0.1 0.4 10.3 0.1 1.5 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) TauD PF02668.16 EON97343.1 - 7.6e-59 199.7 1.0 9.1e-59 199.4 1.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1479 PF07350.12 EON97344.1 - 6.1e-53 180.1 0.0 1.6e-52 178.7 0.0 1.5 1 1 1 2 2 2 2 Protein of unknown function (DUF1479) Aldose_epim PF01263.20 EON97345.1 - 2.6e-61 207.5 0.0 3.4e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Sugar_tr PF00083.24 EON97346.1 - 2.9e-79 267.0 15.9 3.6e-79 266.7 15.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON97346.1 - 2.7e-20 72.6 30.5 1.2e-14 54.1 16.7 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EON97346.1 - 0.0031 16.0 0.5 0.0031 16.0 0.5 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EON97346.1 - 0.0036 16.2 1.3 0.0036 16.2 1.3 2.9 2 1 1 3 3 3 1 MFS_1 like family AMP-binding PF00501.28 EON97347.1 - 1.5e-42 145.7 0.2 1.7e-20 73.0 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 EON97347.1 - 8.8e-12 45.2 0.0 1.9e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_4 PF07993.12 EON97347.1 - 0.00014 21.1 0.5 0.00023 20.4 0.5 1.3 1 0 0 1 1 1 1 Male sterility protein ApbA PF02558.16 EON97348.1 - 5.3e-28 97.6 0.1 7.1e-28 97.2 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EON97348.1 - 9.3e-27 93.7 0.0 1.4e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Aminotran_3 PF00202.21 EON97349.1 - 4.6e-52 177.0 0.4 5.9e-52 176.7 0.4 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF1744 PF08490.12 EON97350.1 - 4.8e-157 522.7 0.0 7e-157 522.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EON97350.1 - 7.2e-79 265.4 0.7 1.1e-78 264.7 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EON97350.1 - 9.8e-15 54.2 0.0 2e-12 46.6 0.0 2.7 2 1 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EON97350.1 - 1.7e-08 34.4 0.1 4.7e-08 33.0 0.1 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EON97350.1 - 1.2e-05 25.3 0.0 5.8e-05 23.1 0.0 2.2 2 1 0 2 2 2 1 RNase_H superfamily adh_short PF00106.25 EON97351.1 - 1.1e-07 31.6 0.0 1.1e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EON97351.1 - 0.0018 18.2 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Ribosomal_S2 PF00318.20 EON97352.1 - 1.8e-65 220.2 0.4 2.8e-64 216.3 0.4 2.2 1 1 0 1 1 1 1 Ribosomal protein S2 Prenylcys_lyase PF07156.14 EON97353.1 - 3.1e-91 306.2 0.0 4.1e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 EON97353.1 - 4.3e-12 46.1 0.0 8.9e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EON97353.1 - 1.7e-10 40.8 0.0 2.3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EON97353.1 - 2.8e-06 27.2 0.2 5.2e-05 23.0 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON97353.1 - 0.0077 15.5 0.1 0.36 10.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 EON97353.1 - 0.02 13.7 0.1 0.85 8.3 0.0 2.2 2 0 0 2 2 2 0 MCRA family NAD_binding_9 PF13454.6 EON97353.1 - 0.025 14.6 0.1 0.091 12.7 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 EON97353.1 - 0.08 12.2 0.1 0.37 10.0 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 EON97353.1 - 0.085 13.4 0.1 8.9 7.0 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AD PF09793.9 EON97353.1 - 0.12 12.5 0.1 0.28 11.3 0.1 1.6 1 0 0 1 1 1 0 Anticodon-binding domain DUF924 PF06041.11 EON97354.1 - 5.2e-06 26.7 0.0 7.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) PQQ_2 PF13360.6 EON97355.1 - 4.1e-12 46.2 0.1 0.00017 21.3 0.8 3.4 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 EON97355.1 - 1.4e-07 31.8 17.8 0.51 10.9 0.0 7.3 7 1 0 7 7 7 4 PQQ-like domain PQQ PF01011.21 EON97355.1 - 2.9e-07 30.1 2.3 0.024 14.6 0.1 6.1 6 0 0 6 6 6 1 PQQ enzyme repeat Pro-kuma_activ PF09286.11 EON97356.1 - 1.8e-24 86.6 0.1 3.4e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Amino_oxidase PF01593.24 EON97357.1 - 4.4e-55 187.8 0.1 5.5e-55 187.4 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.21 EON97357.1 - 2e-17 63.3 0.0 3.4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.6 EON97357.1 - 4.9e-13 49.1 0.3 1.3e-12 47.8 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EON97357.1 - 2e-07 30.5 1.2 3.5e-07 29.7 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EON97357.1 - 3.5e-07 29.7 0.3 6.4e-07 28.9 0.3 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EON97357.1 - 5.2e-07 29.6 0.9 1.4e-05 24.8 0.9 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EON97357.1 - 1e-05 25.1 1.1 1.4e-05 24.6 1.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON97357.1 - 6.7e-05 22.3 0.3 0.00084 18.7 0.4 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON97357.1 - 0.00019 20.3 1.0 0.0004 19.2 0.7 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EON97357.1 - 0.00048 19.3 0.4 0.0009 18.4 0.3 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EON97357.1 - 0.00089 18.4 1.0 0.027 13.5 0.9 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 EON97357.1 - 0.0045 16.3 0.4 0.007 15.7 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EON97357.1 - 0.0082 16.7 0.1 0.017 15.6 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON97357.1 - 0.0093 15.3 0.0 0.062 12.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EON97357.1 - 0.055 12.8 0.2 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AA_permease PF00324.21 EON97358.1 - 5.2e-68 229.8 35.3 4.3e-67 226.8 26.5 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 EON97358.1 - 7.9e-22 77.7 31.8 1.1e-21 77.3 28.0 1.9 1 1 1 2 2 2 2 Amino acid permease SP24 PF16504.5 EON97359.1 - 0.04 13.9 0.3 0.078 13.0 0.3 1.4 1 0 0 1 1 1 0 Putative virion membrane protein of plant and insect virus MFS_1 PF07690.16 EON97360.1 - 5.7e-11 41.9 37.4 4.4e-08 32.4 5.1 3.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EON97360.1 - 4.2e-07 28.8 9.3 4.2e-07 28.8 9.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EON97360.1 - 0.00021 19.7 16.9 0.00051 18.5 0.6 3.2 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family HlyIII PF03006.20 EON97360.1 - 0.00067 19.4 1.2 0.00067 19.4 1.2 2.9 4 0 0 4 4 4 1 Haemolysin-III related MFS_3 PF05977.13 EON97360.1 - 0.004 15.6 1.0 0.004 15.6 1.0 2.9 3 0 0 3 3 3 1 Transmembrane secretion effector Pam17 PF08566.10 EON97360.1 - 0.024 14.5 0.1 0.053 13.4 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 CrgA PF06781.12 EON97360.1 - 0.097 12.7 2.0 0.92 9.6 0.1 3.1 1 1 1 2 2 2 0 Cell division protein CrgA SHR3_chaperone PF08229.11 EON97360.1 - 0.22 10.4 2.7 8.8 5.3 0.2 2.7 2 0 0 2 2 2 0 ER membrane protein SH3 PRA1 PF03208.19 EON97360.1 - 4 7.1 11.7 15 5.2 5.0 3.1 2 1 0 2 2 2 0 PRA1 family protein MFS_1 PF07690.16 EON97361.1 - 8.8e-15 54.5 61.6 1.6e-13 50.4 58.1 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EON97361.1 - 2.3e-05 23.0 21.1 3.5e-05 22.4 19.4 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3043 PF11241.8 EON97361.1 - 6.5 6.7 8.5 27 4.7 2.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3043) adh_short PF00106.25 EON97362.1 - 1.9e-20 73.2 0.0 7.3e-18 64.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON97362.1 - 7.5e-10 38.8 0.0 1.3e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON97362.1 - 4.4e-06 26.7 0.0 6.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON97362.1 - 0.0017 17.8 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family p450 PF00067.22 EON97363.1 - 2e-40 138.9 0.0 2.5e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TAXi_C PF14541.6 EON97363.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Peptidase_M14 PF00246.24 EON97364.1 - 7.2e-39 134.3 0.2 1e-38 133.8 0.2 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Toxin_YhaV PF11663.8 EON97364.1 - 0.06 13.4 0.0 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 Toxin with endonuclease activity, of toxin-antitoxin system Cupin_2 PF07883.11 EON97365.1 - 1.1e-07 31.4 0.0 1.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 EON97365.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Nop14 PF04147.12 EON97366.1 - 5.1 5.2 6.0 5.7 5.0 6.0 1.0 1 0 0 1 1 1 0 Nop14-like family Hydantoinase_B PF02538.14 EON97367.1 - 3.4e-177 590.0 0.1 1.8e-149 498.5 0.0 2.1 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EON97367.1 - 1.5e-98 329.6 0.1 3.2e-98 328.6 0.1 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EON97367.1 - 3.3e-61 206.1 0.4 1.1e-59 201.1 0.0 2.5 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.9 EON97367.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature MFS_2 PF13347.6 EON97368.1 - 0.013 14.1 4.3 0.018 13.6 4.3 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein AA_permease PF00324.21 EON97369.1 - 6.7e-121 404.2 43.3 8.1e-121 403.9 43.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON97369.1 - 6.2e-30 104.4 46.3 7.8e-30 104.0 46.3 1.1 1 0 0 1 1 1 1 Amino acid permease S_4TM PF18159.1 EON97369.1 - 0.054 12.8 0.1 0.2 10.9 0.1 1.9 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Transp_cyt_pur PF02133.15 EON97370.1 - 4.3e-46 157.6 14.3 4.9e-46 157.4 14.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2443 PF10398.9 EON97370.1 - 0.032 14.3 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) FAA_hydrolase PF01557.18 EON97372.1 - 1e-50 172.4 0.0 1.6e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EON97372.1 - 1.2e-32 112.3 0.0 2.3e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Acetyltransf_1 PF00583.25 EON97372.1 - 2.3e-09 37.5 0.1 5.9e-09 36.2 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON97372.1 - 6.1e-09 36.2 0.2 1.4e-08 35.1 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EON97372.1 - 3.5e-08 33.5 0.0 6.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EON97372.1 - 0.00066 19.6 0.1 0.0017 18.2 0.1 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EON97372.1 - 0.025 14.7 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EON97372.1 - 0.03 14.4 0.1 0.084 13.0 0.0 1.8 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain TOC159_MAD PF11886.8 EON97373.1 - 0.02 13.8 0.1 0.031 13.2 0.1 1.2 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain zf-C2H2_4 PF13894.6 EON97373.1 - 0.14 13.0 1.5 1.1 10.3 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EON97373.1 - 0.17 12.4 1.7 0.4 11.2 0.3 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type MFS_1 PF07690.16 EON97374.1 - 5.6e-06 25.5 16.2 1e-05 24.6 12.8 2.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Orf78 PF06024.12 EON97374.1 - 0.017 15.4 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 Orf78 (ac78) DUF4131 PF13567.6 EON97374.1 - 0.17 11.6 4.7 7.1 6.3 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) SLATT_fungal PF18142.1 EON97375.1 - 2.2e-33 114.8 2.9 3.7e-33 114.1 0.0 2.3 2 1 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain DUF2046 PF09755.9 EON97375.1 - 0.0013 18.0 1.3 0.0023 17.2 1.3 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Mer2 PF09074.10 EON97375.1 - 0.016 15.0 2.2 0.02 14.7 1.2 1.6 1 1 0 1 1 1 0 Mer2 Chal_sti_synt_N PF00195.19 EON97375.1 - 0.028 13.8 0.2 0.081 12.3 0.2 1.7 2 0 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain DUF4795 PF16043.5 EON97375.1 - 0.098 12.3 4.6 0.065 12.8 3.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) ApoLp-III PF07464.11 EON97375.1 - 0.29 11.2 3.0 5.1 7.2 1.1 2.9 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Focal_AT PF03623.13 EON97375.1 - 0.79 9.7 4.3 3.1 7.8 1.6 2.6 2 1 0 2 2 2 0 Focal adhesion targeting region Pdase_M17_N2 PF18295.1 EON97375.1 - 0.93 9.8 0.0 0.93 9.8 0.0 2.4 3 1 0 3 3 3 0 M17 aminopeptidase N-terminal domain 2 DUF883 PF05957.13 EON97375.1 - 1.5 9.5 7.5 9.1 7.0 3.0 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Catalase PF00199.19 EON97376.1 - 8.1e-126 420.2 5.7 8e-123 410.3 5.7 2.2 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EON97376.1 - 3.6e-13 49.5 0.6 2.3e-12 46.9 0.1 2.5 2 0 0 2 2 2 1 Catalase-related immune-responsive Cellulase PF00150.18 EON97377.1 - 1.5e-40 139.4 0.5 2e-35 122.6 0.4 2.1 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Peptidase_S10 PF00450.22 EON97378.1 - 8e-40 137.5 8.1 2.5e-39 135.9 8.1 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase GMC_oxred_N PF00732.19 EON97379.1 - 6.7e-54 183.3 0.0 1.2e-53 182.4 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EON97379.1 - 1.6e-35 122.8 0.0 2.3e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EON97379.1 - 2.6e-07 30.5 0.0 5.4e-06 26.2 0.1 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON97379.1 - 1.2e-06 27.9 0.6 0.0032 16.6 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EON97379.1 - 7.8e-05 21.9 0.7 0.00012 21.3 0.7 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EON97379.1 - 0.0003 20.9 0.0 0.00071 19.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EON97379.1 - 0.0016 17.7 0.1 0.003 16.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EON97379.1 - 0.0062 15.8 0.6 0.024 13.9 0.1 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON97379.1 - 0.028 13.7 0.0 0.36 10.1 0.0 2.3 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON97379.1 - 0.24 10.4 0.9 0.48 9.5 0.4 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A COesterase PF00135.28 EON97380.1 - 3.5e-78 263.7 0.7 9e-72 242.6 0.3 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EON97380.1 - 8e-10 38.9 0.0 1.4e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold MccV PF17508.2 EON97380.1 - 0.25 11.9 2.6 3.9 8.1 0.2 3.2 2 1 1 3 3 3 0 Microcin V bacteriocin PTR2 PF00854.21 EON97381.1 - 2.1e-69 234.2 5.6 1.7e-65 221.4 4.4 2.3 1 1 1 2 2 2 2 POT family OPT PF03169.15 EON97382.1 - 8e-144 480.6 46.1 9e-144 480.4 46.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Sugar_tr PF00083.24 EON97383.1 - 9e-40 136.9 18.5 1e-39 136.7 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON97383.1 - 0.0066 15.4 22.8 0.015 14.3 22.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DAO PF01266.24 EON97384.1 - 2.9e-15 56.7 0.1 1.9e-08 34.3 0.0 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EON97384.1 - 0.0077 16.8 1.4 0.019 15.5 1.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON97384.1 - 0.015 15.5 0.7 0.037 14.3 0.2 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EON97384.1 - 0.025 13.8 0.5 0.06 12.6 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EON97384.1 - 0.23 10.7 0.7 0.61 9.3 0.1 1.8 2 0 0 2 2 2 0 Thi4 family DUF4201 PF13870.6 EON97385.1 - 1.1e-06 28.5 76.8 0.00024 20.9 6.0 6.9 1 1 6 7 7 7 3 Domain of unknown function (DUF4201) ERM PF00769.19 EON97385.1 - 4.5e-06 26.7 50.7 4.5e-06 26.7 50.7 3.8 1 1 2 3 3 2 1 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.12 EON97385.1 - 7.9e-06 26.0 132.5 0.0093 16.0 17.6 6.4 1 1 3 5 5 5 4 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 EON97385.1 - 3.6e-05 23.8 103.9 0.015 15.4 25.9 7.0 1 1 5 6 6 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.19 EON97385.1 - 0.00046 18.2 68.1 0.00046 18.2 68.1 2.1 1 1 1 2 2 2 2 Myosin tail DUF1664 PF07889.12 EON97385.1 - 0.00054 20.0 61.4 0.0032 17.5 2.8 6.4 3 1 4 7 7 7 4 Protein of unknown function (DUF1664) LPP PF04728.13 EON97385.1 - 0.00067 20.0 83.5 0.012 16.0 1.6 10.6 6 3 3 10 10 10 5 Lipoprotein leucine-zipper Spc7 PF08317.11 EON97385.1 - 0.00089 18.2 111.5 0.076 11.9 19.9 5.3 1 1 4 5 5 5 3 Spc7 kinetochore protein Fez1 PF06818.15 EON97385.1 - 0.0052 17.3 94.5 0.14 12.6 25.3 4.8 1 1 4 5 5 5 4 Fez1 CortBP2 PF09727.9 EON97385.1 - 0.0068 16.3 20.2 0.0068 16.3 20.2 5.1 1 1 3 4 4 3 1 Cortactin-binding protein-2 FAM184 PF15665.5 EON97385.1 - 0.0097 15.7 21.9 0.0097 15.7 21.9 4.9 1 1 3 4 4 3 2 Family with sequence similarity 184, A and B DUF4407 PF14362.6 EON97385.1 - 0.058 12.7 106.2 0.013 14.8 19.9 4.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) DUF812 PF05667.11 EON97385.1 - 0.064 12.1 101.9 0.013 14.4 30.5 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF812) Filament PF00038.21 EON97385.1 - 0.07 12.7 84.9 1.1 8.7 46.2 5.7 1 1 3 4 4 4 0 Intermediate filament protein Pox_A_type_inc PF04508.12 EON97385.1 - 0.11 12.4 9.7 2.8 7.9 1.7 4.9 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Tup_N PF08581.10 EON97385.1 - 0.11 12.8 0.3 0.11 12.8 0.3 8.6 4 3 3 8 8 8 0 Tup N-terminal GAS PF13851.6 EON97385.1 - 0.16 11.3 95.9 1.5 8.2 25.7 5.5 1 1 4 5 5 5 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 EON97385.1 - 0.41 10.8 57.6 0.088 13.0 9.2 5.6 1 1 2 5 5 5 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 EON97385.1 - 1.7 8.8 102.5 3.7 7.6 3.8 8.3 1 1 5 6 6 6 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.12 EON97385.1 - 2 8.5 47.9 0.11 12.5 4.1 5.5 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 EON97385.1 - 5.9 6.3 89.2 0.033 13.6 16.0 4.4 1 1 3 4 4 4 0 Golgin subfamily A member 5 TMF_TATA_bd PF12325.8 EON97385.1 - 6.4 7.0 90.7 0.1 12.8 9.3 8.0 1 1 6 8 8 7 0 TATA element modulatory factor 1 TATA binding p450 PF00067.22 EON97386.1 - 9.5e-61 205.9 0.0 1.2e-60 205.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LodA_C PF18417.1 EON97386.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 L-lysine epsilon oxidase C-terminal domain Peptidase_S10 PF00450.22 EON97387.1 - 1.7e-86 291.2 0.0 4.4e-86 289.9 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase Hydantoinase_B PF02538.14 EON97388.1 - 2.5e-216 719.1 0.1 3.3e-216 718.7 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EON97388.1 - 1.1e-101 339.9 0.2 9.6e-101 336.9 0.0 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EON97388.1 - 9e-64 214.4 0.2 4e-62 209.1 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region adh_short_C2 PF13561.6 EON97390.1 - 1.6e-52 178.4 0.7 1.6e-52 178.4 0.7 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON97390.1 - 1.3e-46 158.5 1.1 1.3e-46 158.5 1.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.12 EON97390.1 - 2.2e-31 108.0 0.7 2.2e-31 108.0 0.7 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON97390.1 - 5.5e-23 81.4 0.5 5.5e-23 81.4 0.5 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KR PF08659.10 EON97390.1 - 7.6e-12 45.5 1.3 1.4e-11 44.7 1.3 1.4 1 0 0 1 1 1 1 KR domain Glu_dehyd_C PF16912.5 EON97390.1 - 1.5e-06 27.8 0.1 1.4e-05 24.7 0.1 2.3 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EON97390.1 - 1.3e-05 26.2 0.0 0.00011 23.3 0.0 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EON97390.1 - 0.00035 21.2 0.1 0.0022 18.7 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.21 EON97390.1 - 0.029 13.8 0.1 0.062 12.8 0.1 1.7 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EON97390.1 - 0.042 13.2 0.6 1.7 8.0 0.0 2.7 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_31 PF13847.6 EON97390.1 - 0.047 13.5 0.1 0.12 12.1 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 EON97390.1 - 0.054 12.8 0.1 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EON97390.1 - 0.06 12.9 0.3 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CMAS PF02353.20 EON97390.1 - 0.06 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EON97390.1 - 0.087 13.5 0.0 0.24 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Pre-PUA PF17832.1 EON97391.1 - 7.5e-22 77.8 0.6 1.1e-21 77.3 0.6 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EON97391.1 - 4.2e-13 49.1 0.2 1.3e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 PUA domain DUF1947 PF09183.10 EON97391.1 - 0.059 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Sulfatase PF00884.23 EON97392.1 - 1.6e-77 261.0 0.0 1.9e-77 260.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EON97392.1 - 6.2e-05 22.7 0.0 0.27 10.8 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 EON97392.1 - 0.0022 18.2 0.3 0.0096 16.2 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4976) DUF4994 PF16385.5 EON97392.1 - 0.0029 17.5 0.2 0.019 14.9 0.3 2.3 2 1 0 2 2 2 1 Domain of unknown function Sulfatase_C PF14707.6 EON97392.1 - 0.0094 16.7 0.1 0.42 11.3 0.1 2.6 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase TPR_2 PF07719.17 EON97393.1 - 1.5e-06 27.9 0.1 0.0065 16.5 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EON97393.1 - 2e-05 24.2 0.1 4.6e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 EON97393.1 - 0.00012 21.7 0.5 0.033 14.0 0.0 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EON97393.1 - 0.00046 20.4 0.0 0.0016 18.7 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EON97393.1 - 0.033 14.2 0.1 16 5.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Med2 PF11214.8 EON97393.1 - 0.14 12.4 3.0 0.09 12.9 0.6 1.9 2 0 0 2 2 2 0 Mediator complex subunit 2 Nab6_mRNP_bdg PF10567.9 EON97393.1 - 0.15 11.6 1.2 0.21 11.0 1.2 1.3 1 1 0 1 1 1 0 RNA-recognition motif DASH_Dad2 PF08654.10 EON97393.1 - 0.22 12.0 4.6 0.23 11.9 2.7 2.1 2 1 0 2 2 2 0 DASH complex subunit Dad2 AAA_23 PF13476.6 EON97393.1 - 8 6.9 9.0 2.7 8.5 6.3 1.5 2 0 0 2 2 2 0 AAA domain p450 PF00067.22 EON97394.1 - 8.5e-81 272.0 0.0 1e-80 271.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zeta_toxin PF06414.12 EON97394.1 - 0.083 12.2 0.1 0.99 8.6 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Arm PF00514.23 EON97396.1 - 1.3e-75 247.4 31.6 3.9e-13 49.0 0.2 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EON97396.1 - 3.4e-20 72.1 13.9 0.00014 22.3 0.2 7.8 6 2 2 8 8 7 5 HEAT-like repeat HEAT_2 PF13646.6 EON97396.1 - 2.1e-17 63.3 9.7 0.0004 20.7 0.1 7.1 3 2 3 7 7 7 5 HEAT repeats HEAT PF02985.22 EON97396.1 - 2.5e-15 55.3 16.1 0.068 13.5 0.3 8.6 10 0 0 10 10 8 5 HEAT repeat Arm_2 PF04826.13 EON97396.1 - 9.2e-13 48.2 5.6 3.8e-08 33.1 2.2 2.6 1 1 1 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 EON97396.1 - 8.5e-12 44.4 10.6 1.7e-07 30.2 0.5 3.1 2 1 2 4 4 4 2 Adaptin N terminal region KAP PF05804.12 EON97396.1 - 1.3e-10 40.2 0.6 2.7e-10 39.1 0.6 1.5 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 EON97396.1 - 8.4e-09 35.1 3.0 0.00013 21.4 1.4 3.5 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 EON97396.1 - 1.2e-05 25.4 9.8 0.045 13.8 0.1 5.0 2 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 EON97396.1 - 0.00012 22.1 7.4 1.3 9.0 0.0 4.3 2 1 3 5 5 5 3 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 EON97396.1 - 0.00023 21.2 2.7 13 5.9 0.1 4.9 2 1 5 7 7 7 0 V-ATPase subunit H IFRD PF05004.13 EON97396.1 - 0.00039 19.6 2.5 1.4 8.0 0.3 3.9 2 1 1 3 3 3 2 Interferon-related developmental regulator (IFRD) HEAT_PBS PF03130.16 EON97396.1 - 0.00087 19.8 6.0 7.3 7.6 0.4 6.8 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat DUF5578 PF17741.1 EON97396.1 - 0.0012 18.3 7.2 1.6 8.1 0.0 4.7 1 1 3 5 5 5 2 Family of unknown function (DUF5578) Atx10homo_assoc PF09759.9 EON97396.1 - 0.029 14.4 6.9 3.1 7.9 0.3 4.6 3 2 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain Vac14_Fab1_bd PF12755.7 EON97396.1 - 0.033 14.8 0.1 2.5 8.8 0.1 3.4 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region Vpu PF00558.19 EON97396.1 - 0.049 13.4 0.4 0.17 11.6 0.1 2.0 2 0 0 2 2 2 0 Vpu protein UNC45-central PF11701.8 EON97396.1 - 0.084 12.8 4.8 4.5 7.2 0.1 3.7 3 2 0 4 4 4 0 Myosin-binding striated muscle assembly central Fringe PF02434.16 EON97397.1 - 6.1e-07 29.1 1.3 1e-05 25.2 1.3 2.2 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 EON97397.1 - 0.002 18.0 2.9 0.0066 16.3 2.9 1.8 1 0 0 1 1 1 1 PAN domain AAA PF00004.29 EON97398.1 - 7.9e-40 136.3 0.0 1.8e-39 135.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EON97398.1 - 1.7e-18 66.3 0.1 3.4e-18 65.3 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EON97398.1 - 1.8e-07 30.8 0.0 4.4e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EON97398.1 - 0.00012 22.5 1.7 0.018 15.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EON97398.1 - 0.00017 21.6 0.6 0.00067 19.7 0.1 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EON97398.1 - 0.00035 20.3 0.0 0.00087 19.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EON97398.1 - 0.0016 18.6 0.2 0.01 16.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EON97398.1 - 0.0048 17.2 3.7 0.077 13.3 0.0 3.1 3 1 1 4 4 4 1 AAA domain PhoH PF02562.16 EON97398.1 - 0.0055 16.2 0.2 0.077 12.4 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 EON97398.1 - 0.0079 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EON97398.1 - 0.011 14.9 0.0 0.025 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 EON97398.1 - 0.014 15.5 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EON97398.1 - 0.073 12.8 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EON97398.1 - 0.1 12.1 0.0 0.3 10.6 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 EON97398.1 - 0.17 11.6 3.2 0.56 9.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain SAF PF08666.12 EON97399.1 - 1.2e-06 29.0 0.0 2.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 SAF domain GFO_IDH_MocA PF01408.22 EON97399.1 - 8.6e-05 23.3 0.0 0.00028 21.7 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EON97399.1 - 0.00011 22.9 0.1 0.00055 20.6 0.1 2.2 2 1 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 EON97399.1 - 0.16 12.3 0.0 0.95 9.8 0.0 2.3 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Aminotran_3 PF00202.21 EON97400.1 - 2.2e-27 95.8 0.1 2.5e-27 95.6 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Cys_Met_Meta_PP PF01053.20 EON97400.1 - 0.21 10.1 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_transf_8 PF01501.20 EON97401.1 - 3.4e-22 79.3 0.0 6.8e-21 75.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EON97401.1 - 0.0028 17.1 0.0 0.0053 16.2 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative COMPASS-Shg1 PF05205.12 EON97403.1 - 2e-26 92.7 0.0 6.8e-26 90.9 0.0 2.0 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Chitin_synth_2 PF03142.15 EON97404.1 - 1.7e-232 772.7 0.1 2.4e-232 772.3 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 EON97404.1 - 4.1e-16 58.9 0.6 7.4e-12 45.3 0.1 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 EON97404.1 - 9.4e-16 57.5 0.7 7e-15 54.7 1.2 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EON97404.1 - 1.1e-13 51.5 2.8 1.1e-13 51.5 2.8 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EON97404.1 - 1.3e-12 48.1 0.0 5.1e-12 46.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 EON97404.1 - 3.5e-07 28.9 0.0 8.7e-07 27.6 0.0 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 EON97404.1 - 7.6e-05 22.2 0.1 0.0032 17.0 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EON97404.1 - 0.0011 18.8 0.0 0.2 11.4 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Homeodomain PF00046.29 EON97405.1 - 1.8e-19 69.3 4.3 3.4e-19 68.4 4.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EON97405.1 - 0.0016 18.3 0.5 0.0048 16.8 0.5 1.8 1 0 0 1 1 1 1 Homeobox KN domain Hamartin PF04388.12 EON97405.1 - 1.4 7.5 7.4 2.4 6.7 7.4 1.3 1 0 0 1 1 1 0 Hamartin protein Ndc1_Nup PF09531.10 EON97405.1 - 7.8 5.1 7.1 13 4.4 7.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ish1 PF10281.9 EON97406.1 - 8.7e-91 297.9 21.5 1.3e-13 51.0 0.1 8.7 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.27 EON97406.1 - 4.2e-11 42.3 0.0 0.22 11.3 0.0 7.6 8 0 0 8 8 8 3 SAP domain Slx4 PF09494.10 EON97406.1 - 1.3e-06 28.2 0.6 17 5.4 0.0 6.5 6 1 0 6 6 6 1 Slx4 endonuclease HeH PF12949.7 EON97406.1 - 3.9e-06 26.5 3.4 1.5 8.6 0.0 7.3 8 1 0 8 8 8 1 HeH/LEM domain SWIRM PF04433.17 EON97406.1 - 0.013 15.9 0.0 0.71 10.3 0.0 3.1 2 0 0 2 2 2 0 SWIRM domain Thymopoietin PF08198.11 EON97406.1 - 0.041 13.5 0.0 1 9.0 0.0 3.0 4 0 0 4 4 4 0 Thymopoietin protein SAM_2 PF07647.17 EON97406.1 - 0.13 12.4 1.8 2.3 8.4 0.0 3.6 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) Sep15_SelM PF08806.11 EON97406.1 - 0.2 11.9 0.7 21 5.4 0.0 4.0 5 0 0 5 5 5 0 Sep15/SelM redox domain LEA_4 PF02987.16 EON97406.1 - 0.31 11.2 0.1 0.31 11.2 0.1 5.8 6 0 0 6 6 6 0 Late embryogenesis abundant protein DUF2795 PF11387.8 EON97406.1 - 2.2 8.6 4.1 13 6.0 0.2 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2795) F-box PF00646.33 EON97407.1 - 4.8e-07 29.5 0.1 1.3e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EON97407.1 - 4e-06 26.6 0.1 9.9e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 EON97407.1 - 0.017 15.1 0.0 0.076 13.0 0.0 2.1 2 0 0 2 2 2 0 F-box-like domain Dynactin_p22 PF07426.11 EON97407.1 - 0.018 14.9 1.0 0.056 13.3 0.5 2.1 2 0 0 2 2 2 0 Dynactin subunit p22 Muted PF14942.6 EON97407.1 - 0.094 13.1 1.6 0.3 11.4 1.6 1.8 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein YqzE PF14038.6 EON97407.1 - 0.15 12.1 2.6 0.7 9.9 0.0 3.1 4 0 0 4 4 4 0 YqzE-like protein Seryl_tRNA_N PF02403.22 EON97407.1 - 0.46 10.7 10.1 0.06 13.6 4.5 2.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.25 EON97408.1 - 6.9e-59 199.3 0.1 1.1e-57 195.4 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON97408.1 - 2.1e-27 96.0 0.2 3.7e-21 75.6 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EON97408.1 - 1.7e-05 23.9 0.1 2.8e-05 23.2 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EON97408.1 - 0.00015 21.8 0.3 0.023 14.6 0.3 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EON97408.1 - 0.00031 20.2 0.2 0.0012 18.3 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EON97408.1 - 0.00066 19.1 0.3 0.0015 17.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EON97408.1 - 0.053 12.6 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EON97408.1 - 0.38 10.3 3.1 0.45 10.1 0.1 2.1 2 0 0 2 2 2 0 RIO1 family Solute_trans_a PF03619.16 EON97410.1 - 5.3e-100 334.3 10.0 6.4e-100 334.1 10.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha E1_DerP2_DerF2 PF02221.15 EON97411.1 - 1.4e-26 93.5 0.3 1.6e-26 93.3 0.3 1.1 1 0 0 1 1 1 1 ML domain ABM PF03992.16 EON97412.1 - 0.0023 18.0 2.6 0.069 13.3 0.0 3.1 3 1 0 3 3 3 1 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.11 EON97412.1 - 0.013 15.8 0.3 0.034 14.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) Cu-oxidase_2 PF07731.14 EON97413.1 - 8.5e-25 87.1 1.0 1.6e-24 86.2 1.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase Hemerythrin PF01814.23 EON97414.1 - 3.1e-08 34.3 0.2 4.4e-08 33.8 0.2 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain ORC6 PF05460.13 EON97415.1 - 0.0018 17.7 3.5 0.002 17.5 3.5 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) RR_TM4-6 PF06459.12 EON97415.1 - 0.46 10.3 6.2 0.51 10.1 6.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF908 PF06012.12 EON97415.1 - 9.8 5.5 6.7 14 5.0 6.7 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) CBFD_NFYB_HMF PF00808.23 EON97416.1 - 4.1e-09 36.6 0.0 7.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EON97416.1 - 0.031 14.6 0.1 0.057 13.8 0.1 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 SpoIID PF08486.10 EON97416.1 - 0.16 12.5 1.0 0.25 11.9 0.7 1.6 1 1 0 1 1 1 0 Stage II sporulation protein Fungal_trans PF04082.18 EON97417.1 - 1.8e-27 96.0 0.2 4.5e-27 94.7 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EON97417.1 - 1.5e-10 41.0 11.5 2.8e-10 40.1 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain efThoc1 PF11957.8 EON97417.1 - 0.0046 15.7 0.1 0.01 14.5 0.1 1.5 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor ATP11 PF06644.11 EON97417.1 - 6.5 6.5 8.0 0.26 11.1 2.3 1.5 2 0 0 2 2 2 0 ATP11 protein Glyco_hydro_92 PF07971.12 EON97419.1 - 1.5e-75 254.9 2.8 5.3e-62 210.3 0.2 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EON97419.1 - 1e-23 84.5 0.0 1.7e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Glyco_hydro_20 PF00728.22 EON97420.1 - 2.4e-97 326.5 0.3 3e-97 326.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EON97420.1 - 4.4e-27 95.4 0.1 7.6e-27 94.6 0.1 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EON97420.1 - 0.0018 19.1 0.0 0.0046 17.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 PGI PF00342.19 EON97421.1 - 8.7e-224 743.6 0.5 1e-223 743.4 0.5 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase MFS_1 PF07690.16 EON97422.1 - 7.7e-44 150.1 44.8 1.3e-43 149.3 44.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON97422.1 - 1.9e-18 66.6 25.1 5.8e-18 65.0 8.7 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EON97422.1 - 0.0018 16.8 20.3 0.003 16.0 20.3 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4516 PF14990.6 EON97422.1 - 1.9 8.3 4.9 0.54 10.0 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) Hydantoinase_B PF02538.14 EON97423.1 - 1.2e-189 631.1 4.9 3.8e-120 401.7 0.0 2.1 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EON97423.1 - 6.5e-104 347.3 0.0 6.1e-102 340.8 0.0 2.2 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EON97423.1 - 5.3e-55 185.9 0.6 4.8e-53 179.5 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Nipped-B_C PF12830.7 EON97424.1 - 7.2e-50 169.6 3.3 9.1e-48 162.7 2.5 2.7 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EON97424.1 - 2.1e-08 34.3 7.9 2.5e-08 34.0 0.2 3.7 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 EON97424.1 - 1.5e-07 31.0 1.2 0.015 15.5 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.20 EON97424.1 - 8.5e-07 27.9 1.1 1.3e-05 24.0 0.0 3.0 4 0 0 4 4 4 1 Adaptin N terminal region Cnd1 PF12717.7 EON97424.1 - 0.00082 19.5 0.7 0.073 13.1 0.0 3.0 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EON97424.1 - 0.073 12.2 3.8 0.048 12.8 0.3 2.4 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal Cnd3 PF12719.7 EON97424.1 - 0.076 12.2 0.0 3.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain YL1 PF05764.13 EON97424.1 - 0.082 13.0 4.3 0.17 12.0 4.3 1.4 1 0 0 1 1 1 0 YL1 nuclear protein HEAT_EZ PF13513.6 EON97424.1 - 0.093 13.3 0.0 9 6.9 0.0 3.3 2 0 0 2 2 2 0 HEAT-like repeat DUF4942 PF13708.6 EON97424.1 - 0.14 12.2 0.0 0.66 9.9 0.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4942) GCP_C_terminal PF04130.13 EON97424.1 - 0.4 10.1 2.8 4.7 6.6 0.3 2.6 3 0 0 3 3 3 0 Gamma tubulin complex component C-terminal AT_hook PF02178.19 EON97424.1 - 8.8 6.6 10.7 0.34 10.9 4.2 2.2 2 0 0 2 2 2 0 AT hook motif GST_C_3 PF14497.6 EON97425.1 - 1.4e-05 25.2 0.0 2.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EON97425.1 - 0.00065 19.7 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EON97425.1 - 0.0038 17.6 0.2 0.032 14.7 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EON97425.1 - 0.031 14.5 0.1 0.14 12.4 0.0 2.0 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EON97425.1 - 0.041 14.2 0.0 0.073 13.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 EON97425.1 - 0.15 12.6 0.0 0.26 11.9 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SLATT_fungal PF18142.1 EON97426.1 - 9.9e-34 115.9 0.2 1.3e-33 115.5 0.2 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Phage_holin_3_6 PF07332.11 EON97426.1 - 0.002 18.1 0.0 0.0031 17.5 0.0 1.2 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III HD_5 PF13487.6 EON97426.1 - 0.037 14.3 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 HD domain Trp_oprn_chp PF09534.10 EON97426.1 - 0.47 10.2 2.9 3.7 7.3 2.9 2.1 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FMN_dh PF01070.18 EON97427.1 - 6.2e-120 400.4 0.1 7.7e-120 400.1 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EON97427.1 - 1.7e-18 66.5 0.1 2.1e-15 56.6 0.1 2.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EON97427.1 - 2.7e-08 33.4 0.0 4.4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EON97427.1 - 9.5e-05 21.6 1.3 0.00043 19.4 0.0 2.3 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EON97427.1 - 0.00096 18.6 0.1 0.0017 17.9 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 EON97427.1 - 0.0069 15.9 0.9 0.28 10.6 0.1 2.3 1 1 0 2 2 2 1 Histidine biosynthesis protein G3P_antiterm PF04309.12 EON97427.1 - 0.013 14.9 0.0 0.38 10.2 0.0 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator ThiG PF05690.14 EON97427.1 - 0.018 14.4 0.1 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG ECH_2 PF16113.5 EON97428.1 - 4.4e-130 434.0 0.0 9.4e-130 433.0 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EON97428.1 - 2.8e-28 98.9 0.1 7e-28 97.6 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase GCV_H PF01597.19 EON97429.1 - 3.6e-33 114.1 0.9 4.2e-33 113.8 0.9 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Glyco_transf_17 PF04724.13 EON97430.1 - 1.7e-45 155.6 0.4 1e-44 153.0 0.4 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 17 DUF5615 PF18480.1 EON97431.1 - 0.13 12.0 0.2 0.37 10.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) BCDHK_Adom3 PF10436.9 EON97432.1 - 1.8e-45 154.7 0.0 2.6e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EON97432.1 - 4.9e-12 46.3 0.0 2e-11 44.4 0.0 2.0 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ACT_7 PF13840.6 EON97434.1 - 3.7e-06 26.6 0.0 4.5e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 ACT domain LpxD PF04613.14 EON97434.1 - 0.045 13.5 0.1 0.06 13.1 0.1 1.3 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD TIP120 PF08623.10 EON97435.1 - 9.1e-72 240.3 12.4 5.1e-69 231.3 0.0 5.5 5 1 2 7 7 7 2 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 EON97435.1 - 1.5e-12 47.7 20.1 0.059 13.8 0.1 9.1 10 1 0 10 10 8 4 HEAT repeats HEAT PF02985.22 EON97435.1 - 1.2e-11 43.8 30.1 0.12 12.7 0.1 12.4 14 0 0 14 14 12 4 HEAT repeat RTP1_C1 PF10363.9 EON97435.1 - 5.4e-09 36.2 18.7 0.0081 16.3 0.2 8.3 8 1 1 9 9 9 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EON97435.1 - 6.3e-08 32.5 2.6 0.53 9.8 0.1 5.1 3 1 1 4 4 4 3 CLASP N terminal Vac14_Fab1_bd PF12755.7 EON97435.1 - 7.7e-05 23.2 6.3 11 6.8 0.0 6.5 6 3 1 7 7 6 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EON97435.1 - 0.00023 21.2 20.0 0.0041 17.2 0.4 5.5 5 1 1 6 6 5 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 EON97435.1 - 0.00064 19.0 0.7 7.1 5.7 0.0 5.2 6 0 0 6 6 6 1 Nuclear condensing complex subunits, C-term domain V-ATPase_H_C PF11698.8 EON97435.1 - 0.0016 18.5 1.8 5.5 7.1 0.1 4.1 3 1 0 3 3 3 2 V-ATPase subunit H HEAT_EZ PF13513.6 EON97435.1 - 0.0021 18.5 23.2 2.9 8.5 0.0 11.6 13 1 1 14 14 12 1 HEAT-like repeat RasGEF_N_2 PF14663.6 EON97435.1 - 0.0035 17.7 0.9 0.77 10.2 0.0 4.1 4 0 0 4 4 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RIX1 PF08167.12 EON97435.1 - 0.0044 16.8 0.1 3.5 7.3 0.0 4.1 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis DUF720 PF05302.11 EON97435.1 - 0.0052 16.6 0.2 1.8 8.4 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF720) DUF3437 PF11919.8 EON97435.1 - 0.018 14.9 0.7 71 3.4 0.0 5.0 6 0 0 6 6 6 0 Domain of unknown function (DUF3437) DUF5578 PF17741.1 EON97435.1 - 0.049 13.0 1.6 0.51 9.7 0.1 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5578) PUL PF08324.11 EON97435.1 - 0.081 12.2 2.1 0.86 8.8 1.5 2.6 2 1 0 2 2 2 0 PUL domain DUF1308 PF07000.11 EON97435.1 - 0.14 12.1 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) DUF3361 PF11841.8 EON97435.1 - 0.33 10.9 5.3 11 5.9 0.2 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) DUF1512 PF07431.12 EON97435.1 - 0.37 9.8 2.0 2.5 7.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1512) HEAT_PBS PF03130.16 EON97435.1 - 0.76 10.6 5.3 22 6.1 0.1 5.5 6 0 0 6 6 3 0 PBS lyase HEAT-like repeat MMS19_C PF12460.8 EON97435.1 - 0.82 8.7 14.9 1.3 8.1 0.0 5.4 7 1 1 8 8 8 0 RNAPII transcription regulator C-terminal adh_short PF00106.25 EON97436.1 - 1.6e-13 50.6 0.1 2.1e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON97436.1 - 7.2e-12 45.4 0.1 9.5e-12 45.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON97436.1 - 5.9e-09 36.1 0.0 9.5e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EON97436.1 - 0.0066 15.6 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein IF-2B PF01008.17 EON97437.1 - 7.7e-45 153.3 0.1 1.9e-44 152.0 0.1 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family CDC45 PF02724.14 EON97438.1 - 2.7e-93 313.4 33.2 1.7e-61 208.4 22.3 4.0 1 1 1 2 2 2 2 CDC45-like protein DUF3340 PF11818.8 EON97438.1 - 0.014 15.6 9.3 0.028 14.6 9.3 1.4 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) BUD22 PF09073.10 EON97438.1 - 0.034 13.5 12.8 0.048 13.0 12.8 1.1 1 0 0 1 1 1 0 BUD22 FAM60A PF15396.6 EON97438.1 - 0.09 12.8 1.6 0.13 12.2 1.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Cwf_Cwc_15 PF04889.12 EON97438.1 - 0.51 10.0 19.2 0.81 9.4 19.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 EON97438.1 - 2.1 8.5 17.3 3.4 7.9 17.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NPR3 PF03666.13 EON97438.1 - 2.4 6.9 7.3 3.8 6.2 7.3 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Vfa1 PF08432.10 EON97438.1 - 2.8 8.2 10.2 4.2 7.7 10.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Egh16-like PF11327.8 EON97439.1 - 7.7e-54 182.9 7.4 9.5e-54 182.6 7.4 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor adh_short_C2 PF13561.6 EON97440.1 - 3.3e-37 128.3 0.0 3.7e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON97440.1 - 8.3e-18 64.5 0.0 1.1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Aldo_ket_red PF00248.21 EON97441.1 - 1.8e-66 224.3 0.0 2.2e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MMS19_N PF14500.6 EON97441.1 - 0.2 11.2 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Dak1 PF02733.17 EON97442.1 - 1.1e-101 339.9 7.2 1.5e-101 339.4 7.2 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EON97442.1 - 2.1e-44 151.5 0.1 4.4e-44 150.4 0.1 1.6 1 0 0 1 1 1 1 DAK2 domain CLASP_N PF12348.8 EON97443.1 - 1.2e-131 437.1 0.6 8.4e-87 290.5 0.0 2.4 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 EON97443.1 - 5.8e-06 26.1 0.2 1.3 9.5 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EON97443.1 - 0.00046 20.5 0.6 1.2 9.5 0.1 4.9 5 1 0 6 6 6 1 HEAT repeats Cnd1 PF12717.7 EON97443.1 - 0.007 16.4 0.0 1.5 8.9 0.0 3.4 2 2 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EON97443.1 - 0.0088 14.7 0.1 0.043 12.4 0.0 2.2 2 0 0 2 2 2 1 Adaptin N terminal region DUF4704 PF15787.5 EON97443.1 - 0.036 13.3 0.0 5.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) DUF2999 PF11212.8 EON97443.1 - 0.083 13.2 0.1 0.5 10.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2999) AMP-binding PF00501.28 EON97444.1 - 7.8e-96 321.2 0.0 1.2e-95 320.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON97444.1 - 0.00049 21.0 0.3 0.0017 19.3 0.3 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1729 PF08354.10 EON97445.1 - 2.9e-159 529.7 0.0 4.3e-159 529.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EON97445.1 - 1.3e-90 304.1 0.0 1.1e-87 294.5 0.0 3.1 3 0 0 3 3 3 2 Acyl transferase domain FAS_meander PF17951.1 EON97445.1 - 1.7e-54 183.6 0.1 4.7e-54 182.2 0.1 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 EON97445.1 - 1.8e-39 134.7 0.0 5.9e-39 133.0 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 EON97445.1 - 4.9e-39 132.7 0.0 1.3e-38 131.3 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 EON97445.1 - 3e-35 122.1 0.0 7.5e-35 120.8 0.0 1.7 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 EON97445.1 - 4.9e-23 81.7 0.0 1.5e-22 80.1 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.15 EON97445.1 - 0.044 13.2 0.0 2 7.7 0.0 2.4 2 0 0 2 2 2 0 Nitronate monooxygenase DNA_pol_E_B PF04042.16 EON97446.1 - 5.7e-50 169.6 0.0 7.5e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EON97446.1 - 2.1e-40 137.9 0.0 3.2e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain CDI PF02234.19 EON97446.1 - 0.078 13.2 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor PRA-PH PF01503.17 EON97447.1 - 0.057 13.9 0.0 0.078 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase RCC1 PF00415.18 EON97448.1 - 1.8e-54 182.1 9.4 6e-11 42.8 0.0 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EON97448.1 - 4.3e-30 102.9 34.4 5.5e-09 35.6 0.7 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Arylsulfotran_2 PF14269.6 EON97448.1 - 0.12 11.7 0.2 0.52 9.6 0.1 2.0 2 0 0 2 2 2 0 Arylsulfotransferase (ASST) DHDPS PF00701.22 EON97449.1 - 1.4e-31 109.3 0.0 1.6e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Peptidase_M19 PF01244.21 EON97450.1 - 5.3e-93 311.7 0.0 6.1e-93 311.5 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Acetyltransf_3 PF13302.7 EON97452.1 - 4.5e-19 69.5 0.0 5.5e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EON97452.1 - 0.00018 21.4 0.0 0.29 11.1 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_8 PF13523.6 EON97452.1 - 0.00022 20.9 0.0 0.036 13.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON97452.1 - 0.13 12.5 0.0 3.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Fungal_trans PF04082.18 EON97453.1 - 1.1e-68 231.1 0.1 1.5e-68 230.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nop52 PF05997.12 EON97454.1 - 1.4e-59 201.5 0.0 1.7e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 IFT46_B_C PF12317.8 EON97454.1 - 0.0094 15.7 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal HEAT PF02985.22 EON97454.1 - 0.069 13.4 0.1 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat DEAD PF00270.29 EON97455.1 - 6.6e-40 136.7 0.0 1e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON97455.1 - 3.9e-31 107.7 0.2 3.7e-30 104.5 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON97455.1 - 0.00087 19.3 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GLTP PF08718.11 EON97456.1 - 4.4e-48 163.3 0.0 7e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Ribosomal_L4 PF00573.22 EON97457.1 - 7.8e-49 166.0 0.0 1e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family TnsE_C PF18623.1 EON97457.1 - 0.081 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 TnsE C-terminal domain PALP PF00291.25 EON97458.1 - 1.6e-40 139.3 0.2 2e-40 139.1 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ank_4 PF13637.6 EON97459.1 - 6.3e-42 141.4 7.6 5.3e-05 23.7 0.1 12.3 10 3 3 13 13 13 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 EON97459.1 - 4.6e-41 139.3 3.4 5.4e-08 33.3 0.6 8.0 6 2 3 9 9 9 7 Ankyrin repeats (3 copies) Ank PF00023.30 EON97459.1 - 1e-30 104.8 7.4 0.0012 19.2 0.0 11.6 11 0 0 11 11 11 7 Ankyrin repeat Ank_3 PF13606.6 EON97459.1 - 2.8e-28 94.8 12.2 3.5e-05 23.8 0.0 13.6 14 0 0 14 14 14 6 Ankyrin repeat Ank_5 PF13857.6 EON97459.1 - 4.2e-23 81.1 14.9 3.5e-05 24.0 0.0 8.9 8 2 2 10 10 10 5 Ankyrin repeats (many copies) F-box-like PF12937.7 EON97459.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like Esterase PF00756.20 EON97459.1 - 0.09 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative esterase DUF4210 PF13915.6 EON97460.1 - 5.2e-33 113.4 0.1 1.2e-32 112.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 EON97460.1 - 5.8e-23 80.8 0.8 1.1e-22 79.9 0.8 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis Hydrophobin_2 PF06766.11 EON97461.1 - 7.7e-27 93.0 9.4 1e-26 92.6 9.4 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Ribosomal_S13 PF00416.22 EON97462.1 - 6e-17 62.2 0.3 1.2e-14 54.8 0.3 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 PRP1_N PF06424.12 EON97463.1 - 0.034 14.5 0.0 0.052 14.0 0.0 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal MFS_1 PF07690.16 EON97464.1 - 3.1e-37 128.3 27.0 3.1e-37 128.3 27.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5090 PF17009.5 EON97464.1 - 0.023 14.7 0.3 0.061 13.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Trp_oprn_chp PF09534.10 EON97464.1 - 1.6 8.5 5.9 11 5.8 0.2 2.6 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TauD PF02668.16 EON97465.1 - 3.3e-21 76.3 0.0 4.5e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family F_bP_aldolase PF01116.20 EON97466.1 - 6.3e-87 291.6 0.2 7.1e-87 291.4 0.2 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II AA_permease PF00324.21 EON97467.1 - 1.8e-26 92.8 23.9 6.5e-24 84.4 20.4 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 EON97467.1 - 5.2e-11 42.0 24.1 9.8e-11 41.1 24.1 1.6 1 1 0 1 1 1 1 Amino acid permease ORC2 PF04084.14 EON97468.1 - 4.8e-107 357.7 0.0 6e-107 357.4 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 NMD3 PF04981.13 EON97469.1 - 3e-79 265.9 1.3 5.6e-79 265.0 1.3 1.4 1 0 0 1 1 1 1 NMD3 family Mit_ribos_Mrp51 PF11709.8 EON97470.1 - 7.4e-98 328.5 0.0 9.5e-98 328.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit FAD_binding_3 PF01494.19 EON97471.1 - 5.6e-16 58.7 0.1 7.6e-12 45.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EON97471.1 - 1.6e-07 31.3 0.2 0.0083 15.7 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON97471.1 - 2.8e-07 30.0 0.1 0.00045 19.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON97471.1 - 0.00013 22.1 0.0 0.0003 20.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EON97471.1 - 0.008 14.9 0.0 0.1 11.3 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 EON97471.1 - 0.017 14.3 0.4 0.065 12.3 0.3 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 EON97471.1 - 0.027 13.7 0.0 0.076 12.2 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EON97471.1 - 0.034 14.1 0.0 0.08 12.9 0.0 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 EON97471.1 - 0.047 12.9 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EON97471.1 - 0.12 13.0 0.0 0.69 10.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EON97471.1 - 0.13 11.0 0.2 1.1 8.0 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 EON97471.1 - 0.16 11.0 0.5 3 6.8 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein TRI12 PF06609.13 EON97472.1 - 2.1e-10 39.7 3.5 2.5e-10 39.4 3.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EON97472.1 - 0.00016 20.7 15.8 0.0036 16.3 15.8 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 EON97472.1 - 0.74 9.9 6.6 0.17 12.0 0.6 2.4 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4131 PF13567.6 EON97472.1 - 1.7 8.3 3.7 7.8 6.1 3.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) FAD_binding_3 PF01494.19 EON97473.1 - 7.9e-23 81.2 0.1 1.5e-22 80.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EON97473.1 - 2.6e-08 33.8 8.3 0.0031 17.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EON97473.1 - 1.7e-07 31.4 1.5 4.5e-07 30.0 1.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EON97473.1 - 1.1e-06 28.0 1.0 0.0043 16.2 6.6 2.1 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EON97473.1 - 6.9e-06 25.5 1.9 2.2e-05 23.8 1.9 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EON97473.1 - 2.3e-05 23.9 4.3 0.026 13.8 2.3 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EON97473.1 - 3.5e-05 22.7 2.3 9.6e-05 21.3 2.3 1.6 1 1 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 EON97473.1 - 7.8e-05 22.2 1.2 0.00012 21.5 1.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EON97473.1 - 0.00015 20.8 5.0 0.00068 18.6 2.5 2.4 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 EON97473.1 - 0.00018 22.0 1.9 0.00074 20.0 0.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON97473.1 - 0.0038 16.5 5.4 0.17 11.1 5.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON97473.1 - 0.005 16.0 1.7 0.0076 15.4 1.7 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EON97473.1 - 0.017 14.4 5.7 0.078 12.3 2.9 2.6 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Rossmann-like PF10727.9 EON97473.1 - 0.093 12.6 0.4 0.2 11.5 0.4 1.5 1 0 0 1 1 1 0 Rossmann-like domain Thi4 PF01946.17 EON97473.1 - 0.17 11.1 1.1 0.3 10.3 1.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EON97473.1 - 0.32 10.0 2.3 1.1 8.2 2.3 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EON97473.1 - 0.71 9.9 5.1 6.9 6.6 0.9 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Kelch_3 PF13415.6 EON97474.1 - 2.5e-13 49.9 7.6 0.0011 19.2 0.6 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.6 EON97474.1 - 5.5e-12 45.5 5.5 0.0068 16.4 0.7 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EON97474.1 - 1.1e-09 38.1 10.0 5.6e-07 29.4 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 EON97474.1 - 1.5e-05 25.1 6.2 0.13 12.6 0.4 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 EON97474.1 - 0.00012 21.6 8.2 0.074 12.6 0.3 4.5 4 0 0 4 4 4 2 Kelch motif Fungal_trans_2 PF11951.8 EON97476.1 - 1.2e-05 24.3 0.0 1.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EON97476.1 - 0.00023 21.2 2.5 0.00045 20.3 2.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transglut_core PF01841.19 EON97477.1 - 0.0005 20.5 0.0 0.0012 19.3 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily CzcE PF16986.5 EON97477.1 - 0.012 15.9 0.2 0.028 14.7 0.0 1.8 2 0 0 2 2 2 0 Heavy-metal resistance protein CzcE Gln_amidase PF15644.6 EON97477.1 - 0.013 16.5 0.0 0.022 15.7 0.0 1.5 1 0 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase CoA_transf_3 PF02515.17 EON97478.1 - 4.4e-120 401.2 0.0 5e-120 401.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III PPR_2 PF13041.6 EON97479.1 - 8.7e-41 137.9 15.5 1.6e-08 34.6 0.0 13.5 10 5 6 16 16 16 5 PPR repeat family PPR_3 PF13812.6 EON97479.1 - 9.4e-33 112.1 1.1 0.0025 17.8 0.0 11.3 7 3 5 13 13 13 7 Pentatricopeptide repeat domain PPR PF01535.20 EON97479.1 - 9.9e-23 78.8 27.8 0.0012 19.0 0.1 13.5 17 0 0 17 17 16 6 PPR repeat PPR_1 PF12854.7 EON97479.1 - 1.6e-21 75.7 3.4 1.4e-07 31.1 0.0 9.9 12 0 0 12 12 12 4 PPR repeat PPR_long PF17177.4 EON97479.1 - 2.2e-16 59.8 13.7 8.5e-08 31.8 0.3 6.3 4 2 2 6 6 6 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 EON97479.1 - 8.7e-05 22.9 0.0 0.002 18.5 0.0 3.0 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 EON97479.1 - 0.0039 17.0 0.7 0.069 13.0 0.1 3.3 3 1 1 4 4 4 1 Mitochondrial ATPase expression SelB-wing_2 PF09106.11 EON97479.1 - 0.051 13.8 0.0 2.4 8.4 0.0 4.1 6 0 0 6 6 5 0 Elongation factor SelB, winged helix DUF3835 PF12927.7 EON97479.1 - 0.15 12.9 0.2 17 6.3 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) DUF3562 PF12085.8 EON97479.1 - 0.18 11.4 0.6 33 4.2 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3562) DUF4129 PF13559.6 EON97479.1 - 7.3 6.9 6.7 37 4.7 0.7 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4129) ATP-synt_F PF01990.17 EON97480.1 - 6.3e-34 116.2 0.0 8e-34 115.8 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit MTHFR PF02219.17 EON97481.1 - 8.9e-114 379.6 0.0 2.4e-113 378.2 0.0 1.6 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase Sec7 PF01369.20 EON97481.1 - 0.098 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Sec7 domain Glyco_hydro_28 PF00295.17 EON97482.1 - 1.1e-23 83.8 13.8 3.9e-23 82.0 13.8 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 UDPGT PF00201.18 EON97482.1 - 0.11 11.2 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Pyr_redox_3 PF13738.6 EON97483.1 - 5.4e-18 65.3 0.0 2.6e-15 56.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EON97483.1 - 3e-16 59.0 0.0 1e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EON97483.1 - 2.2e-15 56.7 0.0 4.9e-12 45.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON97483.1 - 1.9e-08 33.8 0.2 1e-06 28.2 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EON97483.1 - 0.00022 21.4 0.0 0.0014 18.8 0.0 2.4 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EON97483.1 - 0.00022 21.7 0.2 1.1 9.9 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EON97483.1 - 0.0007 18.9 0.0 0.26 10.5 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain TrkA_N PF02254.18 EON97483.1 - 0.018 15.3 0.1 8.8 6.6 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain IlvN PF07991.12 EON97483.1 - 0.046 13.3 0.1 0.14 11.7 0.1 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Cuticle_1 PF08140.11 EON97483.1 - 0.048 13.7 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Crustacean cuticle protein repeat GIDA PF01134.22 EON97483.1 - 0.094 11.8 0.0 12 4.8 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 EON97483.1 - 0.099 12.0 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mur_ligase PF01225.25 EON97483.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, catalytic domain Shikimate_DH PF01488.20 EON97483.1 - 0.15 12.2 0.0 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EON97483.1 - 0.2 11.5 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DEP PF00610.21 EON97484.1 - 8.2e-14 51.4 0.0 1.8e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 EON97484.1 - 6.8e-11 42.3 0.4 8e-10 38.9 0.0 2.7 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Med4 PF10018.9 EON97484.1 - 4.6e-05 23.2 0.2 4.6e-05 23.2 0.2 2.2 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 BAR PF03114.18 EON97484.1 - 0.022 14.4 4.3 0.03 14.0 0.6 2.3 2 0 0 2 2 2 0 BAR domain DUF5343 PF17278.2 EON97484.1 - 0.071 13.2 0.3 0.18 11.9 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5343) KIP1 PF07765.12 EON97484.1 - 0.09 12.9 1.2 9.3 6.5 0.0 3.7 4 0 0 4 4 4 0 KIP1-like protein DUF4771 PF15995.5 EON97484.1 - 3.5 7.9 7.6 1.7 8.9 0.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4771) TMF_DNA_bd PF12329.8 EON97484.1 - 6.6 6.8 8.2 6.3 6.9 1.0 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PBP PF01161.20 EON97485.1 - 7.4e-07 29.5 0.0 1.2e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Cyclase PF04199.13 EON97486.1 - 2.5e-15 56.9 0.0 3.2e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Methyltransf_23 PF13489.6 EON97487.1 - 2.7e-20 72.9 0.0 3.2e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON97487.1 - 2e-14 54.1 0.0 5.1e-14 52.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON97487.1 - 1e-12 48.5 0.0 2e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON97487.1 - 6.6e-08 32.5 0.0 0.0057 16.5 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EON97487.1 - 1.1e-07 32.5 0.0 1.7e-06 28.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON97487.1 - 1.4e-06 27.8 0.0 0.027 13.8 0.0 2.4 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EON97487.1 - 0.00038 20.0 0.0 0.00046 19.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EON97487.1 - 0.0019 17.7 0.0 0.0054 16.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EON97487.1 - 0.011 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 EON97487.1 - 0.013 15.2 0.0 0.045 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF938) FtsJ PF01728.19 EON97487.1 - 0.032 14.3 0.0 0.071 13.2 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase PCMT PF01135.19 EON97487.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Glyco_hydro_32C PF08244.12 EON97488.1 - 4.5e-19 69.0 0.1 7.5e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 EON97488.1 - 2e-17 63.7 0.0 3.7e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Methyltransf_32 PF13679.6 EON97489.1 - 4.1e-23 82.1 0.0 7.8e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 EON97490.1 - 6.6e-32 110.8 25.8 6.6e-32 110.8 25.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON97490.1 - 1.5e-12 47.2 19.3 1.2e-11 44.2 19.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter SoxG PF04268.12 EON97491.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family Sugar_tr PF00083.24 EON97492.1 - 5.3e-82 276.1 26.8 7.1e-67 226.2 9.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EON97492.1 - 6.7e-19 68.0 36.1 2.7e-09 36.4 1.6 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1 PF07690.16 EON97493.1 - 2.4e-38 132.0 49.3 2e-36 125.7 49.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EON97493.1 - 5.1e-10 38.4 22.0 7.4e-10 37.9 22.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EON97493.1 - 6.6e-10 38.4 9.9 6.6e-10 38.4 9.9 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter ATG22 PF11700.8 EON97493.1 - 0.61 8.6 24.3 0.17 10.5 14.5 3.4 3 1 0 3 3 3 0 Vacuole effluxer Atg22 like Aldo_ket_red PF00248.21 EON97494.1 - 2.9e-41 141.6 0.0 3.9e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family 4HBT PF03061.22 EON97495.1 - 0.01 16.1 0.8 0.22 11.9 0.1 2.3 2 0 0 2 2 2 0 Thioesterase superfamily MFS_1 PF07690.16 EON97496.1 - 7.6e-18 64.6 6.0 3.3e-16 59.2 3.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON97496.1 - 2.7e-16 59.5 12.7 3.4e-16 59.2 5.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 EON97496.1 - 0.0007 18.3 5.1 0.00099 17.8 5.1 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein Phage_holin_2_4 PF16082.5 EON97496.1 - 0.13 12.0 0.4 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Pex2_Pex12 PF04757.14 EON97497.1 - 6.6e-52 176.3 4.8 8.5e-52 176.0 4.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 EON97497.1 - 0.0017 18.1 2.0 0.0028 17.5 2.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EON97497.1 - 0.0089 15.8 2.8 0.016 15.1 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EON97497.1 - 0.011 16.1 3.3 0.018 15.3 3.3 1.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 EON97497.1 - 0.023 14.8 2.1 0.038 14.1 2.1 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EON97497.1 - 0.24 11.3 3.3 0.44 10.5 3.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_76 PF03663.14 EON97498.1 - 1.1e-152 508.8 16.8 1.3e-152 508.6 16.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EON97498.1 - 0.00081 18.6 5.9 0.11 11.6 0.4 3.1 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 RNA_lig_T4_1 PF09511.10 EON97499.1 - 6.6e-86 287.7 0.0 1.4e-85 286.7 0.0 1.6 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 EON97499.1 - 4.8e-54 182.9 0.1 1.1e-53 181.8 0.1 1.6 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 EON97499.1 - 8.6e-54 182.7 0.5 1.4e-53 182.0 0.5 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_18 PF13238.6 EON97499.1 - 0.0028 18.2 0.2 0.044 14.3 0.2 3.0 1 1 0 1 1 1 1 AAA domain RNA_ligase PF09414.10 EON97499.1 - 0.023 15.0 0.0 0.063 13.6 0.0 1.8 1 0 0 1 1 1 0 RNA ligase Peptidase_M41 PF01434.18 EON97500.1 - 3e-68 229.5 0.0 4.9e-68 228.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EON97500.1 - 1.5e-43 148.4 0.0 3.5e-43 147.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EON97500.1 - 2.2e-11 43.4 0.2 5.6e-11 42.1 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EON97500.1 - 1.2e-08 35.3 0.0 2.8e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_16 PF13191.6 EON97500.1 - 0.003 18.0 0.3 0.15 12.4 0.2 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.6 EON97500.1 - 0.0033 17.8 0.9 0.35 11.3 0.0 3.6 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 EON97500.1 - 0.0039 17.2 0.0 0.014 15.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EON97500.1 - 0.0049 17.1 0.1 1.1 9.5 0.1 2.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EON97500.1 - 0.0066 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 EON97500.1 - 0.0092 15.7 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EON97500.1 - 0.026 14.6 0.0 0.081 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EON97500.1 - 0.038 13.7 0.2 0.11 12.2 0.0 1.8 2 1 0 2 2 2 0 IstB-like ATP binding protein Inhibitor_I78 PF11720.8 EON97501.1 - 1.9e-10 40.6 0.0 2.4e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 EON97501.1 - 0.015 16.0 0.0 0.022 15.4 0.0 1.3 1 0 0 1 1 1 0 Potato inhibitor I family Ras PF00071.22 EON97502.1 - 1.4e-31 109.2 0.1 1.8e-31 108.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EON97502.1 - 4.3e-24 85.0 0.1 7.5e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EON97502.1 - 1.4e-06 27.9 0.1 1.8e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EON97502.1 - 0.00022 20.7 0.1 0.00029 20.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 EON97502.1 - 0.002 17.0 0.3 0.16 10.8 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) DUF4603 PF15376.6 EON97503.1 - 0.069 10.6 0.0 0.079 10.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Sec5 PF15469.6 EON97504.1 - 9.1e-39 133.2 0.0 4e-38 131.1 0.0 2.1 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 EON97504.1 - 8.1e-06 25.8 0.5 0.00042 20.3 0.0 3.1 2 0 0 2 2 2 1 Vps51/Vps67 Sec15 PF04091.12 EON97504.1 - 0.0014 18.1 0.2 0.0027 17.2 0.2 1.4 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like DUF1932 PF09130.11 EON97504.1 - 0.064 13.2 0.1 0.26 11.3 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) GATA PF00320.27 EON97505.1 - 0.00017 21.1 6.1 0.019 14.5 1.9 2.6 2 0 0 2 2 2 2 GATA zinc finger Flavin_Reduct PF01613.18 EON97506.1 - 3.7e-16 59.6 0.0 4.9e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF4261 PF14080.6 EON97506.1 - 0.051 13.7 0.0 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4261) Glyco_hydro_3 PF00933.21 EON97508.1 - 4.2e-19 69.1 0.0 6e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DUF4926 PF16277.5 EON97509.1 - 0.082 12.3 0.0 0.33 10.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) UPF0086 PF01868.16 EON97510.1 - 5.9e-31 106.2 0.3 9e-31 105.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Hamartin PF04388.12 EON97511.1 - 1.2 7.7 12.2 1.7 7.2 12.2 1.2 1 0 0 1 1 1 0 Hamartin protein FAM60A PF15396.6 EON97511.1 - 5.8 6.9 11.7 23 4.9 11.7 1.9 1 1 0 1 1 1 0 Protein Family FAM60A Rrn6 PF10214.9 EON97511.1 - 6.6 5.1 14.5 7.9 4.8 14.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor V_ATPase_I PF01496.19 EON97511.1 - 8.4 4.2 9.9 11 3.7 9.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Borrelia_P83 PF05262.11 EON97511.1 - 9.3 4.6 22.1 12 4.2 22.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein BTB PF00651.31 EON97512.1 - 1.5e-05 25.2 0.0 3.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF966 PF06136.13 EON97512.1 - 0.069 12.9 13.4 0.099 12.3 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) NAD_binding_11 PF14833.6 EON97513.1 - 2e-38 131.4 0.1 1.4e-24 86.6 0.0 2.9 2 1 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 EON97513.1 - 6e-34 117.5 0.2 9.9e-34 116.8 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EON97513.1 - 0.0007 20.1 0.0 0.0018 18.8 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EON97513.1 - 0.0028 17.5 0.2 0.006 16.5 0.2 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EON97513.1 - 0.014 15.0 0.1 0.049 13.3 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Ribosomal_L22 PF00237.19 EON97513.1 - 0.13 12.5 0.0 18 5.7 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e Mago_nashi PF02792.14 EON97514.1 - 2.8e-72 241.5 0.6 3.1e-72 241.3 0.6 1.0 1 0 0 1 1 1 1 Mago nashi protein HSP70 PF00012.20 EON97515.1 - 4.9e-267 887.0 15.7 5.7e-267 886.8 15.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EON97515.1 - 1.2e-14 53.9 4.7 7.5e-13 48.0 1.0 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EON97515.1 - 5.9e-05 22.9 0.2 0.00061 19.6 0.1 2.4 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 EON97515.1 - 0.0047 16.2 3.2 0.14 11.4 0.1 3.4 3 1 1 4 4 4 1 StbA protein DUF4363 PF14276.6 EON97515.1 - 0.4 10.8 6.8 0.88 9.7 6.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Melibiase_2 PF16499.5 EON97516.1 - 2.6e-06 26.8 2.1 2.4e-05 23.7 0.9 2.4 1 1 1 2 2 2 1 Alpha galactosidase A Glyco_hydro_31 PF01055.26 EON97516.1 - 0.0011 18.3 0.1 0.0014 17.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_hydro_15 PF00723.21 EON97517.1 - 8.5e-81 272.0 0.1 1.1e-80 271.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EON97517.1 - 1e-20 73.4 0.6 2.2e-20 72.4 0.6 1.6 1 0 0 1 1 1 1 Starch binding domain Pyr_redox_2 PF07992.14 EON97518.1 - 6.7e-05 22.3 0.2 0.0015 17.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON97518.1 - 0.0032 17.7 1.0 0.011 15.9 1.0 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EON97518.1 - 0.0053 16.1 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 EON97518.1 - 0.057 12.6 0.3 0.17 11.1 0.3 1.8 1 1 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EON97518.1 - 0.085 11.9 0.3 0.63 9.0 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein zf-CCHH PF10283.9 EON97518.1 - 0.09 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 PBZ domain HI0933_like PF03486.14 EON97518.1 - 0.27 9.9 0.8 5.1 5.7 0.4 2.1 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 EON97518.1 - 0.32 10.5 1.7 0.59 9.7 1.7 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase MFS_1 PF07690.16 EON97519.1 - 3.5e-37 128.1 29.8 3.5e-37 128.1 29.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Epimerase PF01370.21 EON97520.1 - 1.9e-15 57.0 0.0 2.5e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EON97520.1 - 6.6e-08 32.7 0.5 1.1e-07 31.9 0.5 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EON97520.1 - 9.5e-08 31.4 0.1 1.3e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EON97520.1 - 7.4e-07 28.9 0.1 0.00013 21.5 0.1 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EON97520.1 - 9.6e-07 28.2 0.3 2.6e-06 26.8 0.3 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 EON97520.1 - 1.9e-06 27.6 0.6 2.9e-06 27.0 0.3 1.5 2 0 0 2 2 2 1 NmrA-like family TrkA_N PF02254.18 EON97520.1 - 0.00016 21.9 0.1 0.00035 20.8 0.1 1.7 1 1 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EON97520.1 - 0.00068 19.9 0.3 0.0014 18.9 0.3 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 EON97520.1 - 0.00086 18.8 0.2 0.019 14.4 0.1 2.3 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EON97520.1 - 0.0014 17.8 0.9 0.003 16.8 0.4 1.8 2 1 1 3 3 3 1 Male sterility protein Lipase_3 PF01764.25 EON97521.1 - 1.1e-33 116.1 0.0 1.8e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EON97521.1 - 2.8e-05 23.5 0.0 4.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON97521.1 - 0.00075 20.2 0.1 0.001 19.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase3_N PF03893.16 EON97521.1 - 0.014 15.4 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 Lipase 3 N-terminal region Abhydrolase_8 PF06259.12 EON97521.1 - 0.02 14.5 0.1 0.04 13.6 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF2974 PF11187.8 EON97521.1 - 0.25 10.8 0.8 1.3 8.5 0.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) GTP_EFTU PF00009.27 EON97522.1 - 3.4e-66 222.5 0.2 5e-66 221.9 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EON97522.1 - 3.3e-33 114.0 0.0 9.7e-33 112.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EON97522.1 - 2.9e-22 78.5 0.0 8e-21 73.9 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EON97522.1 - 2.1e-12 47.3 0.1 7.2e-12 45.5 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EON97522.1 - 1.6e-11 44.1 0.0 4.5e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EON97522.1 - 0.0017 18.4 0.2 0.0043 17.1 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SF3A2 PF16835.5 EON97523.1 - 2.4e-35 120.8 0.1 3.6e-35 120.2 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EON97523.1 - 3.9e-06 27.1 0.9 7.1e-06 26.2 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 EON97523.1 - 8.9e-05 22.4 0.2 0.00014 21.8 0.2 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 EON97523.1 - 0.07 12.7 1.5 0.12 12.0 1.5 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Adaptin_N PF01602.20 EON97524.1 - 2.7e-94 316.6 7.1 4.5e-94 315.9 7.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 EON97524.1 - 3.6e-59 198.7 0.2 7.7e-59 197.6 0.2 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 EON97524.1 - 3.1e-57 192.1 0.0 8.1e-57 190.7 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 EON97524.1 - 1.1e-13 51.5 2.4 3.4e-10 40.2 0.0 3.0 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EON97524.1 - 1.3e-09 38.4 2.0 0.0003 21.1 0.0 5.3 2 2 3 5 5 5 2 HEAT repeats Coatomer_g_Cpla PF16381.5 EON97524.1 - 0.00041 20.5 0.0 0.0011 19.1 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform AP4E_app_platf PF14807.6 EON97524.1 - 0.0037 17.6 0.4 0.012 15.9 0.4 2.0 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform HEAT PF02985.22 EON97524.1 - 0.0039 17.3 2.2 3.3 8.2 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat DUF5578 PF17741.1 EON97524.1 - 0.0092 15.4 1.4 2.3 7.6 0.1 2.6 2 0 0 2 2 2 2 Family of unknown function (DUF5578) DAGK_cat PF00781.24 EON97525.1 - 1.5e-23 82.8 0.0 2.4e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PRKCSH-like PF12999.7 EON97525.1 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Glyco_hydro_71 PF03659.14 EON97526.1 - 6.9e-102 341.1 14.2 2.1e-88 296.7 9.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 71 Glyco_hydro_3_C PF01915.22 EON97527.1 - 1.1e-45 156.1 0.0 3.2e-45 154.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EON97527.1 - 5.9e-23 80.8 0.1 1.2e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 EON97527.1 - 6.8e-16 58.5 0.0 1e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain CARDB PF07705.11 EON97527.1 - 0.027 14.7 0.0 0.062 13.6 0.0 1.6 1 0 0 1 1 1 0 CARDB 3HCDH_N PF02737.18 EON97528.1 - 1.3e-52 178.3 0.1 1.7e-52 177.9 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EON97528.1 - 4.8e-33 113.7 0.0 9.4e-33 112.7 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 EON97528.1 - 0.00099 19.4 0.1 0.0026 18.0 0.1 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 EON97528.1 - 0.0065 16.7 0.2 0.016 15.4 0.1 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.24 EON97528.1 - 0.035 13.7 0.1 0.05 13.2 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON97528.1 - 0.04 13.1 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EON97528.1 - 0.09 12.3 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 EON97528.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EON97528.1 - 1.1 9.9 3.5 1.6 9.4 1.8 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF1996 PF09362.10 EON97529.1 - 7.2e-12 45.8 1.7 1.1e-11 45.2 1.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) BCS1_N PF08740.11 EON97530.1 - 6.9e-28 97.9 0.4 1.4e-27 96.9 0.0 1.6 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 EON97530.1 - 6.4e-17 62.2 0.0 1.6e-07 31.8 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EON97530.1 - 0.00073 19.3 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 EON97530.1 - 0.015 15.1 1.1 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EON97530.1 - 0.021 15.2 0.1 0.069 13.5 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EON97530.1 - 0.04 13.9 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EON97530.1 - 0.043 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EON97530.1 - 0.06 12.7 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 EON97530.1 - 0.088 13.0 0.3 0.23 11.6 0.3 2.1 1 1 0 1 1 1 0 AAA domain Gram_pos_anchor PF00746.21 EON97531.1 - 0.17 11.9 1.1 0.4 10.7 0.2 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Adeno_E3_CR2 PF02439.15 EON97531.1 - 1.9 8.3 4.1 0.88 9.4 0.1 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Nefa_Nip30_N PF10187.9 EON97533.1 - 3.2e-30 104.6 10.8 3.2e-30 104.6 10.8 2.7 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 VIT1 PF01988.19 EON97533.1 - 0.4 10.5 3.3 0.66 9.8 3.3 1.4 1 0 0 1 1 1 0 VIT family Opacity PF02462.15 EON97534.1 - 0.057 13.5 0.5 0.16 12.1 0.1 1.9 2 0 0 2 2 2 0 Opacity family porin protein Zw10 PF06248.13 EON97535.1 - 2.9e-11 42.6 5.4 3.3e-06 26.0 2.9 2.4 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 EON97535.1 - 9.4e-05 22.2 0.1 0.00028 20.6 0.1 1.8 1 1 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Com_YlbF PF06133.11 EON97535.1 - 0.058 14.0 2.3 0.29 11.7 2.3 2.3 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA FIVAR PF07554.13 EON97535.1 - 0.82 10.5 3.7 2.9 8.7 1.1 3.1 1 1 1 2 2 2 0 FIVAR domain ThiF PF00899.21 EON97536.1 - 6.9e-113 376.0 0.0 5.8e-76 255.1 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EON97536.1 - 2.9e-92 309.1 1.8 4.4e-92 308.6 1.8 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 EON97536.1 - 1.3e-32 112.3 0.1 1.2e-31 109.2 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin fold domain E1_FCCH PF16190.5 EON97536.1 - 3.9e-32 110.3 0.1 9.1e-32 109.1 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 EON97536.1 - 5.2e-26 90.6 1.4 1.1e-25 89.6 0.5 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 EON97536.1 - 0.051 14.0 0.0 1.2 9.6 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding SH3_1 PF00018.28 EON97537.1 - 4.1e-09 35.9 0.2 1.2e-08 34.4 0.2 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EON97537.1 - 7.8e-08 32.1 0.3 2e-07 30.8 0.3 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EON97537.1 - 8.6e-07 28.6 0.0 2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Herpes_UL25 PF01499.16 EON97537.1 - 2.2 6.7 4.4 4.6 5.6 4.4 1.4 1 0 0 1 1 1 0 Herpesvirus UL25 family MFS_1 PF07690.16 EON97538.1 - 4.8e-08 32.3 3.4 5e-08 32.3 3.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5090 PF17009.5 EON97538.1 - 0.0065 16.5 1.2 0.05 13.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5090) NDUF_B8 PF05821.11 EON97538.1 - 0.05 13.5 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) ATP-synt_F PF01990.17 EON97539.1 - 0.021 15.1 0.2 0.035 14.4 0.2 1.3 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit Exotox-A_target PF09102.10 EON97539.1 - 0.042 13.8 1.9 0.082 12.9 1.9 1.4 1 0 0 1 1 1 0 Exotoxin A, targeting PepSY_TM PF03929.16 EON97539.1 - 0.15 11.7 0.0 11 5.6 0.0 2.3 2 0 0 2 2 2 0 PepSY-associated TM region adh_short PF00106.25 EON97540.1 - 7.1e-35 120.2 0.1 9.4e-35 119.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON97540.1 - 1.6e-23 83.5 0.0 2e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EON97540.1 - 0.00012 22.0 0.1 0.00023 21.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 EON97540.1 - 0.00021 20.8 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 EON97540.1 - 0.00026 21.0 0.5 0.00047 20.1 0.2 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KR PF08659.10 EON97540.1 - 0.002 18.1 0.2 0.0032 17.4 0.2 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EON97540.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 EON97540.1 - 0.041 13.3 0.0 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EON97540.1 - 0.051 14.2 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 EON97540.1 - 0.094 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain PGP_phosphatase PF09419.10 EON97541.1 - 6.1e-65 217.9 0.0 7.1e-65 217.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EON97541.1 - 4e-05 23.6 0.0 6.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like eIF3g PF12353.8 EON97542.1 - 5.6e-45 152.8 2.6 1e-44 151.9 2.6 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EON97542.1 - 2.8e-15 55.9 0.0 4.9e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 EON97542.1 - 0.016 15.5 0.2 0.032 14.6 0.2 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 RRM_occluded PF16842.5 EON97542.1 - 0.14 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif Methyltransf_23 PF13489.6 EON97543.1 - 9.1e-10 38.6 0.0 1.4e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON97543.1 - 9.1e-07 29.5 0.0 1.7e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON97543.1 - 9.7e-06 25.5 0.0 5.7e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON97543.1 - 0.00032 21.3 0.0 0.00062 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON97543.1 - 0.00045 20.9 0.0 0.0026 18.5 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 EON97543.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 EON97543.1 - 0.026 14.1 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 EON97543.1 - 0.03 13.7 0.0 0.33 10.3 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EON97543.1 - 0.055 13.6 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase UPF0020 PF01170.18 EON97544.1 - 1.8e-07 31.0 0.1 0.00068 19.4 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Sugar_tr PF00083.24 EON97545.1 - 5.3e-73 246.4 19.5 6e-73 246.2 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON97545.1 - 1.3e-11 44.1 16.7 1.3e-11 44.1 16.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4225 PF13988.6 EON97545.1 - 0.29 10.7 1.5 0.54 9.8 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) TMEM18 PF14770.6 EON97545.1 - 0.73 9.8 4.4 0.33 11.0 1.3 2.0 2 0 0 2 2 2 0 Transmembrane protein 18 Orn_Arg_deC_N PF02784.16 EON97547.1 - 1.6e-85 286.4 0.0 2.2e-85 286.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EON97547.1 - 7.4e-19 67.8 0.0 1.1e-18 67.3 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain MFS_1 PF07690.16 EON97548.1 - 1.5e-30 106.3 30.2 1.5e-30 106.3 30.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily UPF0715 PF17094.5 EON97548.1 - 0.31 11.6 4.3 0.17 12.5 0.7 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0715) Nop16 PF09420.10 EON97549.1 - 6.5e-65 219.1 2.0 7.5e-65 218.9 2.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 p450 PF00067.22 EON97550.1 - 6.1e-36 124.1 0.0 7.9e-36 123.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M16_C PF05193.21 EON97551.1 - 5.1e-19 69.0 0.0 3.7e-16 59.7 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EON97551.1 - 3.7e-07 30.2 0.0 4e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) RXT2_N PF08595.11 EON97551.1 - 0.0059 16.6 1.8 0.012 15.7 1.8 1.4 1 0 0 1 1 1 1 RXT2-like, N-terminal M16C_assoc PF08367.11 EON97551.1 - 0.038 13.1 5.8 0.23 10.5 5.7 2.1 1 1 0 1 1 1 0 Peptidase M16C associated Sporozoite_P67 PF05642.11 EON97551.1 - 0.058 11.5 4.2 0.086 10.9 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YlbD_coat PF14071.6 EON97551.1 - 0.11 12.7 5.2 0.43 10.8 5.2 2.0 1 0 0 1 1 1 0 Putative coat protein Sigma70_ner PF04546.13 EON97551.1 - 0.64 9.9 9.5 0.2 11.5 4.3 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.14 EON97551.1 - 1.1 7.5 5.2 1.5 7.0 5.2 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EON97551.1 - 5.2 6.3 14.6 7.4 5.8 14.6 1.2 1 0 0 1 1 1 0 NOA36 protein Dak1 PF02733.17 EON97552.1 - 1.4e-100 336.2 0.0 1.9e-100 335.8 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EON97552.1 - 9e-43 146.2 2.1 9e-43 146.2 2.1 1.9 2 0 0 2 2 2 1 DAK2 domain Peptidase_S24 PF00717.23 EON97553.1 - 9.7e-07 28.7 0.4 1.7e-06 27.9 0.4 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EON97553.1 - 5.4e-06 26.2 0.0 0.00044 20.0 0.0 2.6 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Anemone_cytotox PF06369.12 EON97554.1 - 0.063 12.9 0.2 0.1 12.2 0.1 1.3 1 1 0 1 1 1 0 Sea anemone cytotoxic protein Anoctamin PF04547.12 EON97555.1 - 2.1e-120 402.6 10.6 2.6e-120 402.3 10.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DER1 PF04511.15 EON97555.1 - 0.0064 16.4 3.3 0.019 14.9 3.3 1.8 1 0 0 1 1 1 1 Der1-like family MARVEL PF01284.23 EON97556.1 - 6.3e-10 39.2 5.8 8.7e-10 38.8 5.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4281 PF14108.6 EON97556.1 - 6.2e-05 23.4 1.7 0.00011 22.6 1.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) YtpI PF14007.6 EON97556.1 - 0.019 15.1 0.2 0.031 14.4 0.2 1.3 1 0 0 1 1 1 0 YtpI-like protein DUF5134 PF17197.4 EON97556.1 - 0.061 13.2 0.4 0.09 12.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) Voltage_CLC PF00654.20 EON97557.1 - 9.2e-88 294.8 28.2 9.2e-88 294.8 28.2 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EON97557.1 - 1.4e-10 41.4 0.1 5.7e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain Rox3 PF08633.10 EON97558.1 - 7.2e-71 238.7 0.2 9.8e-71 238.3 0.2 1.1 1 0 0 1 1 1 1 Rox3 mediator complex subunit Aldedh PF00171.22 EON97559.1 - 6.6e-130 433.7 0.0 8.1e-130 433.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EON97559.1 - 0.00047 19.3 0.0 0.0012 18.0 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 EON97559.1 - 0.1 12.0 0.0 3.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) GMC_oxred_C PF05199.13 EON97560.1 - 1.7e-31 109.7 0.0 2.6e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EON97560.1 - 1.4e-26 93.5 0.0 4.6e-18 65.6 0.0 3.1 3 0 0 3 3 3 2 GMC oxidoreductase NAD_binding_8 PF13450.6 EON97560.1 - 1.8e-05 24.9 0.1 7e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EON97560.1 - 8.1e-05 22.0 0.0 0.00041 19.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON97560.1 - 0.00052 19.4 0.0 0.67 9.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON97560.1 - 0.0058 15.8 0.0 0.015 14.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EON97560.1 - 0.015 14.6 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EON97560.1 - 0.028 13.1 0.0 0.053 12.2 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 EON97560.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Nif11 PF07862.11 EON97561.1 - 1.9 8.9 4.0 8.9 6.7 0.6 3.7 4 1 0 4 4 4 0 Nif11 domain Vac_ImportDeg PF09783.9 EON97562.1 - 5.7e-61 205.0 0.9 6.8e-61 204.8 0.9 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein Dala_Dala_lig_C PF07478.13 EON97562.1 - 0.05 13.1 0.0 0.067 12.7 0.0 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus MFS_1 PF07690.16 EON97563.1 - 0.031 13.2 0.1 0.037 13.0 0.1 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Serglycin PF04360.12 EON97564.1 - 0.027 14.4 0.6 0.042 13.8 0.6 1.3 1 0 0 1 1 1 0 Serglycin SR-25 PF10500.9 EON97564.1 - 0.054 13.1 6.4 0.088 12.4 6.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SNF2_N PF00176.23 EON97565.1 - 2.2e-49 168.0 0.1 6.9e-48 163.1 0.1 2.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EON97565.1 - 4.1e-09 36.8 0.0 1.5e-08 34.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON97565.1 - 1.3e-08 35.0 0.2 7.5e-08 32.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EON97565.1 - 9.8e-05 22.2 15.5 9.8e-05 22.2 15.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 EON97565.1 - 0.00079 18.4 0.0 0.002 17.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-RING_2 PF13639.6 EON97565.1 - 0.0022 18.3 15.7 0.0022 18.3 15.7 2.4 2 0 0 2 2 2 1 Ring finger domain FAM176 PF14851.6 EON97565.1 - 0.023 14.3 0.2 0.023 14.3 0.2 2.3 2 1 1 3 3 3 0 FAM176 family AT_hook PF02178.19 EON97565.1 - 0.031 14.1 14.9 0.4 10.7 4.5 3.2 2 0 0 2 2 2 0 AT hook motif DUF3246 PF11596.8 EON97565.1 - 10 5.5 18.6 0.068 12.6 4.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3246) Amidohydro_2 PF04909.14 EON97566.1 - 3e-44 152.0 0.1 3.7e-44 151.7 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase GHMP_kinases_N PF00288.26 EON97567.1 - 5.2e-16 58.6 1.5 1.2e-15 57.5 1.5 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EON97567.1 - 2.6e-10 40.5 0.1 8.3e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal DUF2196 PF09962.9 EON97567.1 - 0.029 14.3 0.0 7.4 6.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2196) NAP PF00956.18 EON97568.1 - 1.2e-29 103.4 2.6 1.5e-28 99.7 2.5 2.0 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Cwf_Cwc_15 PF04889.12 EON97568.1 - 0.0038 17.0 3.2 0.0038 17.0 3.2 2.3 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Cir_N PF10197.9 EON97568.1 - 0.031 14.4 0.1 0.031 14.4 0.1 2.9 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR CENP-B_dimeris PF09026.10 EON97568.1 - 0.68 10.3 18.6 0.77 10.2 7.4 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 EON97568.1 - 4 7.9 16.0 1.1 9.6 5.2 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 EON97568.1 - 6.1 4.8 19.5 9.1 4.2 19.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAT PF02259.23 EON97569.1 - 3.5e-74 250.1 11.6 4.8e-74 249.6 9.9 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EON97569.1 - 3.6e-33 115.4 0.0 1.2e-31 110.5 0.1 2.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase AMP-binding PF00501.28 EON97569.1 - 1.7e-17 63.2 0.0 3.2e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EON97569.1 - 9.3e-06 25.5 0.8 2.7e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus HEAT PF02985.22 EON97569.1 - 0.078 13.3 2.2 4.2 7.9 0.1 4.4 4 0 0 4 4 4 0 HEAT repeat AAA_32 PF13654.6 EON97569.1 - 0.092 11.5 0.0 0.23 10.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_8 PF13181.6 EON97569.1 - 0.14 12.4 4.2 0.24 11.7 0.4 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EON97569.1 - 2.4 8.7 3.9 37 5.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EON97569.1 - 4.4 7.7 12.1 5.9 7.3 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Aa_trans PF01490.18 EON97570.1 - 4e-86 289.3 33.4 4.9e-86 289.0 33.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RNA_pol_L_2 PF13656.6 EON97570.1 - 1.2e-21 76.2 0.0 2.1e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EON97570.1 - 9.7e-06 24.9 0.0 4.4e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MitoNEET_N PF10660.9 EON97570.1 - 0.31 11.1 5.3 7.7 6.6 0.6 3.4 3 0 0 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus TFIIB PF00382.19 EON97571.1 - 9.2e-35 118.5 0.8 3.9e-20 71.7 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EON97571.1 - 5.7e-10 38.5 1.4 1e-09 37.8 1.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 EON97571.1 - 9.8e-05 22.4 0.0 0.021 14.9 0.0 2.3 1 1 1 2 2 2 1 Cyclin, C-terminal domain RB_B PF01857.20 EON97571.1 - 0.0067 16.5 0.2 0.017 15.2 0.0 1.7 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain HTH_5 PF01022.20 EON97571.1 - 0.0099 15.7 0.0 0.69 9.8 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_Tnp_ISL3 PF13542.6 EON97571.1 - 0.029 13.8 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DUF2815 PF10991.8 EON97571.1 - 0.059 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) Sigma70_r4 PF04545.16 EON97571.1 - 0.064 12.8 0.0 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 Cyclin_N PF00134.23 EON97571.1 - 0.096 12.4 0.7 2.1 8.1 0.0 2.6 2 1 0 2 2 2 0 Cyclin, N-terminal domain Rrf2 PF02082.20 EON97571.1 - 0.11 12.8 0.0 16 6.0 0.0 2.8 2 1 1 3 3 3 0 Transcriptional regulator Sigma70_r4_2 PF08281.12 EON97571.1 - 0.12 12.0 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 PALP PF00291.25 EON97572.1 - 8.5e-45 153.4 2.3 1e-44 153.1 2.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Adeno_shaft PF00608.17 EON97572.1 - 0.035 13.9 0.2 0.091 12.6 0.2 1.6 1 0 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) Pantoate_ligase PF02569.15 EON97573.1 - 7.2e-92 307.4 0.0 9.4e-92 307.0 0.0 1.1 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase STAS PF01740.21 EON97574.1 - 5.5e-08 32.5 0.0 7.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EON97574.1 - 0.0047 17.2 0.0 0.0094 16.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain LSM PF01423.22 EON97575.1 - 6.5e-18 64.2 0.1 8.8e-18 63.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EON97575.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Inhibitor_I9 PF05922.16 EON97576.1 - 1.9e-13 50.9 0.1 3e-13 50.2 0.1 1.3 1 1 0 1 1 1 1 Peptidase inhibitor I9 GGACT PF06094.12 EON97577.1 - 8.9e-17 61.8 0.0 1.2e-16 61.4 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like cobW PF02492.19 EON97579.1 - 4.7e-42 143.6 0.0 6.5e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EON97579.1 - 0.00059 19.7 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 EON97579.1 - 0.0037 17.0 0.0 0.0079 16.0 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EON97579.1 - 0.011 16.0 0.0 0.028 14.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EON97579.1 - 0.014 14.6 0.1 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 EON97579.1 - 0.026 14.3 0.1 0.33 10.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AbiEi_3 PF11459.8 EON97579.1 - 0.034 13.8 0.0 0.32 10.7 0.0 2.3 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system AAA_16 PF13191.6 EON97579.1 - 0.036 14.4 0.0 0.089 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EON97579.1 - 0.051 13.5 0.0 5.3 6.9 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase TrwB_AAD_bind PF10412.9 EON97579.1 - 0.073 12.0 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF4598 PF15370.6 EON97579.1 - 0.082 13.4 0.3 3 8.4 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4598) NTPase_1 PF03266.15 EON97579.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 EON97579.1 - 0.091 12.8 0.1 0.34 11.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 EON97579.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 EON97579.1 - 0.14 12.1 0.0 0.71 9.7 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF463 PF04317.12 EON97579.1 - 0.17 10.8 0.1 0.29 10.0 0.1 1.4 1 0 0 1 1 1 0 YcjX-like family, DUF463 CRC_subunit PF08624.10 EON97580.1 - 6.4e-52 175.6 0.0 1.2e-51 174.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit DUF4746 PF15928.5 EON97580.1 - 0.6 9.5 10.4 1.1 8.6 10.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 EON97580.1 - 1.8 6.7 3.3 2.5 6.3 3.3 1.1 1 0 0 1 1 1 0 CDC45-like protein FoP_duplication PF13865.6 EON97580.1 - 2.2 8.9 7.1 0.6 10.7 3.2 2.0 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 NMO PF03060.15 EON97581.1 - 3.3e-49 168.1 0.3 4.8e-49 167.5 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EON97581.1 - 5.5e-08 32.2 0.4 1.4e-06 27.6 0.2 2.3 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EON97581.1 - 7.2e-05 22.0 1.8 0.00017 20.8 1.7 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase TPR_1 PF00515.28 EON97583.1 - 4.4e-30 102.3 5.5 5.5e-05 22.8 0.5 9.8 9 0 0 9 9 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EON97583.1 - 1e-29 102.5 15.8 3.2e-23 81.7 0.3 5.5 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EON97583.1 - 4e-28 95.2 16.4 0.00058 19.8 0.2 10.7 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_19 PF14559.6 EON97583.1 - 1.4e-24 86.3 10.7 0.0014 19.1 0.1 7.7 5 2 3 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 EON97583.1 - 6.3e-21 74.5 15.0 3.9e-08 33.5 0.1 8.6 7 2 0 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 EON97583.1 - 7.5e-21 73.0 13.9 0.0013 19.4 0.1 9.6 5 3 6 11 11 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 EON97583.1 - 4.8e-19 66.9 5.7 0.0078 16.4 0.1 9.8 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 EON97583.1 - 6.6e-16 58.7 11.8 0.00043 20.9 0.0 7.8 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EON97583.1 - 8.5e-13 47.4 14.7 0.12 12.5 0.0 9.3 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 EON97583.1 - 1.9e-10 40.3 4.9 0.21 11.3 0.0 7.8 7 1 2 9 9 9 3 TPR repeat TPR_10 PF13374.6 EON97583.1 - 6.6e-10 38.5 10.9 0.18 11.7 0.2 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 EON97583.1 - 3.9e-08 33.4 15.6 0.96 10.2 0.2 8.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 EON97583.1 - 6.7e-06 26.2 11.4 0.016 15.3 0.3 6.2 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 EON97583.1 - 8.2e-06 25.2 5.3 0.098 11.9 0.1 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat RPN7 PF10602.9 EON97583.1 - 0.00058 19.6 0.6 1.4 8.6 0.0 4.1 3 1 1 4 4 4 1 26S proteasome subunit RPN7 MIT PF04212.18 EON97583.1 - 0.017 15.2 1.3 27 4.9 0.0 4.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 EON97583.1 - 0.022 15.1 9.0 56 4.4 0.0 7.6 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_21 PF09976.9 EON97583.1 - 0.05 13.3 4.2 6.4 6.4 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 EON97583.1 - 0.093 13.4 6.0 7.7 7.5 0.0 5.6 7 0 0 7 7 4 0 Tetratricopeptide repeat PPR PF01535.20 EON97583.1 - 0.1 12.9 1.1 68 4.0 0.0 4.8 5 0 0 5 5 4 0 PPR repeat SHNi-TPR PF10516.9 EON97583.1 - 0.11 12.0 0.4 4.6 6.8 0.0 3.5 4 0 0 4 4 4 0 SHNi-TPR TEX29 PF15839.5 EON97583.1 - 0.4 11.3 1.4 13 6.5 0.3 2.5 1 1 1 2 2 2 0 Testis-expressed sequence 29 protein PLDc PF00614.22 EON97584.1 - 8.2e-15 54.3 0.8 2.7e-07 30.5 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EON97584.1 - 4.2e-14 52.6 0.0 3.1e-05 23.9 0.0 4.3 4 0 0 4 4 4 3 PLD-like domain WD40 PF00400.32 EON97585.1 - 1e-22 80.0 14.6 2.1e-08 34.7 0.3 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat NLE PF08154.12 EON97585.1 - 1.6e-16 60.6 0.2 2.9e-16 59.7 0.2 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 EON97585.1 - 3.3e-05 22.7 2.4 0.006 15.3 0.1 3.6 1 1 2 4 4 4 1 Nucleoporin Nup120/160 DUF3943 PF13084.6 EON97585.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) CDC45 PF02724.14 EON97586.1 - 2.9e-67 227.4 0.0 3.3e-67 227.2 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Haem_degrading PF03928.14 EON97587.1 - 2.5e-33 114.6 0.0 3.1e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading FAS_I_H PF18314.1 EON97588.1 - 1.8e-77 259.6 0.6 5.5e-77 258.0 0.0 2.2 3 0 0 3 3 3 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 EON97588.1 - 3.2e-75 251.9 0.0 5.9e-75 251.1 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 EON97588.1 - 1.7e-21 77.0 0.1 3.3e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 EON97588.1 - 5.2e-19 68.5 0.1 1.6e-18 66.9 0.0 1.9 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EON97588.1 - 2.7e-11 43.5 0.0 7e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EON97588.1 - 0.0022 17.9 0.0 0.0087 16.0 0.0 2.1 1 0 0 1 1 1 1 KR domain CUE PF02845.16 EON97589.1 - 2.6e-08 33.4 0.0 4.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain WSC PF01822.19 EON97590.1 - 1.2e-12 47.9 7.0 1.2e-12 47.9 7.0 3.1 3 1 0 3 3 3 1 WSC domain Glyco_hydro_16 PF00722.21 EON97590.1 - 1.6e-05 24.4 0.2 8.6e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 TSLP PF15216.6 EON97590.1 - 2.4 8.5 5.7 0.44 10.8 1.9 1.6 2 0 0 2 2 2 0 Thymic stromal lymphopoietin Esterase_phd PF10503.9 EON97591.1 - 0.00066 19.2 0.2 0.0011 18.5 0.2 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase LSM PF01423.22 EON97592.1 - 2.9e-22 78.1 0.1 3.3e-22 78.0 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EON97592.1 - 0.1 12.8 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain AAA PF00004.29 EON97593.1 - 2.4e-11 44.2 0.0 5e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EON97593.1 - 3.3e-06 27.4 0.0 9.9e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EON97593.1 - 9.1e-06 25.7 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EON97593.1 - 7.5e-05 22.5 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EON97593.1 - 0.00015 21.7 0.0 0.00044 20.2 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 EON97593.1 - 0.00042 20.5 0.4 0.0019 18.4 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 EON97593.1 - 0.0013 18.8 0.0 0.0041 17.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EON97593.1 - 0.0022 18.4 0.4 0.011 16.2 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EON97593.1 - 0.0072 16.1 0.5 0.032 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EON97593.1 - 0.022 14.6 0.0 0.084 12.8 0.0 2.1 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 EON97593.1 - 0.054 14.0 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EON97593.1 - 0.065 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 EON97593.1 - 0.081 13.3 0.7 1.1 9.5 0.3 2.8 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EON97593.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 EON97593.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EON97593.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain MT0933_antitox PF14013.6 EON97594.1 - 0.39 11.1 5.5 4.7 7.6 5.5 2.5 1 1 0 1 1 1 0 MT0933-like antitoxin protein Methyltransf_3 PF01596.17 EON97595.1 - 2.7e-12 46.3 0.0 4.6e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EON97595.1 - 1.6e-11 45.1 0.0 4.2e-11 43.8 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Glycos_transf_3 PF00591.21 EON97596.1 - 1.4e-59 201.8 0.0 2.5e-59 200.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EON97596.1 - 3.4e-12 46.0 0.0 7.9e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain SGTA_dimer PF16546.5 EON97597.1 - 1.1e-26 92.4 0.4 2e-26 91.5 0.4 1.5 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 EON97597.1 - 5.3e-16 57.4 10.0 8.3e-07 28.7 0.7 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EON97597.1 - 5.3e-16 57.7 12.6 5.4e-08 32.3 1.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EON97597.1 - 3e-09 36.4 8.9 3.3e-05 23.5 2.9 3.4 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.6 EON97597.1 - 1.4e-08 35.2 22.0 2.8e-08 34.2 7.9 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EON97597.1 - 1.7e-08 34.0 10.4 0.022 14.9 0.2 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EON97597.1 - 1.8e-07 31.4 8.5 0.031 15.1 2.1 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EON97597.1 - 2.2e-07 31.1 4.7 7e-07 29.4 2.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EON97597.1 - 1.9e-06 27.8 6.0 0.00076 19.7 0.8 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EON97597.1 - 2.5e-06 27.9 8.1 8.6e-05 23.0 2.7 3.3 1 1 1 2 2 2 2 Tetratricopeptide repeat STI1 PF17830.1 EON97597.1 - 3e-05 23.9 10.8 0.00092 19.1 7.0 3.0 3 0 0 3 3 3 1 STI1 domain BTAD PF03704.17 EON97597.1 - 0.00015 22.2 1.2 0.14 12.6 0.1 2.3 1 1 1 2 2 2 2 Bacterial transcriptional activator domain TPR_10 PF13374.6 EON97597.1 - 0.00035 20.3 6.6 0.029 14.2 0.8 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EON97597.1 - 0.00036 20.3 0.9 0.027 14.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EON97597.1 - 0.0051 16.9 0.7 0.075 13.2 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EON97597.1 - 0.017 15.7 7.5 0.44 11.3 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat XPC-binding PF09280.11 EON97597.1 - 0.039 13.7 1.2 0.076 12.8 0.8 1.7 2 0 0 2 2 2 0 XPC-binding domain Wzy_C_2 PF11846.8 EON97597.1 - 0.38 10.7 1.8 0.59 10.0 1.8 1.3 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DnaJ_C PF01556.18 EON97598.1 - 9e-39 132.9 0.0 1.2e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EON97598.1 - 6.3e-25 87.1 1.9 9.1e-25 86.6 1.9 1.2 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EON97598.1 - 9.5e-11 41.9 21.1 2e-10 40.9 21.1 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EON97598.1 - 0.072 13.1 14.1 0.59 10.1 2.6 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EON97598.1 - 0.64 10.1 9.5 1.7 8.7 1.1 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrome_C7 PF14522.6 EON97598.1 - 0.85 9.7 9.6 2 8.4 0.4 2.5 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c DZR PF12773.7 EON97598.1 - 4.1 7.5 8.5 4.5 7.4 1.3 2.2 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 EON97598.1 - 8.9 6.4 7.0 38 4.4 7.3 1.8 1 1 1 2 2 2 0 zinc-ribbons Cyclin PF08613.11 EON97599.1 - 1.8e-09 38.2 0.0 3.9e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin RSN1_7TM PF02714.15 EON97599.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate Rep_fac-A_3 PF08661.11 EON97600.1 - 7.4e-21 74.5 0.0 8.2e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 IF3_C PF00707.22 EON97601.1 - 2.3e-11 43.5 1.5 3.9e-11 42.8 1.5 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 EON97601.1 - 1.2e-06 28.3 1.1 3.9e-06 26.6 0.8 1.8 1 1 1 2 2 2 1 Mitochondrial translation initiation factor DUF3563 PF12086.8 EON97601.1 - 0.097 12.4 0.3 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3563) Peptidase_M48_N PF16491.5 EON97602.1 - 2.5e-65 219.8 7.5 2.5e-65 219.8 7.5 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EON97602.1 - 4.4e-45 153.9 0.0 8.8e-45 152.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 EON97602.1 - 0.0089 15.3 0.1 0.02 14.1 0.1 1.5 1 0 0 1 1 1 1 BlaR1 peptidase M56 PPTA PF01239.22 EON97603.1 - 4.5e-37 124.7 12.5 7.4e-07 28.7 0.1 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_7 PF13176.6 EON97603.1 - 0.003 17.5 1.6 1.3 9.2 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TauD PF02668.16 EON97604.1 - 1.1e-51 176.2 0.1 1.3e-51 175.9 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Integrin_b_cyt PF08725.11 EON97604.1 - 0.23 11.2 0.4 0.54 10.0 0.0 1.8 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain TauD PF02668.16 EON97605.1 - 7e-64 216.2 0.8 9e-64 215.8 0.8 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4291 PF14124.6 EON97607.1 - 1.1e-70 237.2 0.2 1.4e-70 236.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) tRNA-synt_1g PF09334.11 EON97608.1 - 1.9e-99 333.1 0.2 1e-97 327.4 0.2 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EON97608.1 - 2e-25 89.1 7.0 7e-10 37.8 0.2 3.9 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EON97608.1 - 3.2e-10 39.8 0.0 7.9e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 EON97608.1 - 0.00053 20.0 0.0 0.0031 17.5 0.1 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA DUF5331 PF17265.2 EON97608.1 - 0.018 14.8 0.1 0.036 13.8 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5331) Acyltransferase PF01553.21 EON97609.1 - 1.1e-15 57.5 0.0 2e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Sugar_tr PF00083.24 EON97610.1 - 1.6e-115 386.6 20.6 1.8e-115 386.4 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON97610.1 - 7.8e-25 87.5 22.9 7.8e-25 87.5 22.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_5 PF05631.14 EON97610.1 - 0.0051 15.8 0.8 0.0051 15.8 0.8 1.9 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Cyt-b5 PF00173.28 EON97612.1 - 4.6e-13 49.1 0.0 7.6e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RPAP2_Rtr1 PF04181.13 EON97613.1 - 1.1e-22 80.1 0.2 2.1e-22 79.2 0.2 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family Pro_CA PF00484.19 EON97614.1 - 9.3e-51 172.2 0.0 9.3e-51 172.2 0.0 1.4 2 0 0 2 2 2 1 Carbonic anhydrase PNP_UDP_1 PF01048.20 EON97614.1 - 0.052 12.8 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphorylase superfamily PRK PF00485.18 EON97615.1 - 3.4e-06 26.9 0.0 5.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 EON97615.1 - 4.9e-06 25.9 0.0 8.5e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 EON97615.1 - 3e-05 24.6 0.0 9.1e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EON97615.1 - 6.9e-05 22.6 0.1 0.00017 21.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EON97615.1 - 0.00016 22.1 0.0 0.00026 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EON97615.1 - 0.00018 21.9 0.0 0.00036 20.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EON97615.1 - 0.00022 20.5 0.0 0.00044 19.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 EON97615.1 - 0.00024 21.5 0.0 0.00036 20.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 EON97615.1 - 0.00036 20.5 0.0 0.0046 17.0 0.0 2.1 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EON97615.1 - 0.00051 20.2 0.1 0.0029 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EON97615.1 - 0.0013 19.1 0.0 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EON97615.1 - 0.0013 19.2 0.1 0.014 15.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EON97615.1 - 0.0036 16.9 0.0 0.0074 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EON97615.1 - 0.0039 16.9 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EON97615.1 - 0.0049 16.8 0.0 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA_5 PF07728.14 EON97615.1 - 0.0065 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EON97615.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.6 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.6 EON97615.1 - 0.02 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EON97615.1 - 0.021 13.9 0.0 0.039 13.0 0.0 1.4 2 0 0 2 2 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 EON97615.1 - 0.021 15.3 0.0 0.046 14.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 EON97615.1 - 0.027 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CPT PF07931.12 EON97615.1 - 0.028 14.3 0.1 0.28 11.0 0.1 2.2 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein cobW PF02492.19 EON97615.1 - 0.028 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EON97615.1 - 0.044 13.3 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 EON97615.1 - 0.049 13.5 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 EON97615.1 - 0.052 13.5 0.0 0.079 12.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 EON97615.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EON97615.1 - 0.06 13.1 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Torsin PF06309.11 EON97615.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Torsin RuvB_N PF05496.12 EON97615.1 - 0.072 12.8 0.1 0.15 11.8 0.0 1.5 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 EON97615.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain RNA_helicase PF00910.22 EON97615.1 - 0.075 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.10 EON97615.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TIP49 PF06068.13 EON97615.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Cytidylate_kin PF02224.18 EON97615.1 - 0.19 11.5 0.0 0.19 11.5 0.0 1.5 2 0 0 2 2 1 0 Cytidylate kinase Parvo_NS1 PF01057.17 EON97615.1 - 0.24 10.5 0.0 0.4 9.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 zf-BED PF02892.15 EON97616.1 - 0.0097 15.9 0.6 0.022 14.8 0.2 1.9 2 0 0 2 2 2 1 BED zinc finger Zn_clus PF00172.18 EON97616.1 - 0.02 15.0 5.9 0.047 13.8 5.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_6 PF13912.6 EON97616.1 - 0.023 14.7 2.5 0.45 10.6 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger TF_Zn_Ribbon PF08271.12 EON97616.1 - 0.11 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding SUIM_assoc PF16619.5 EON97616.1 - 2.7 8.1 6.8 0.54 10.4 0.1 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 GST_N_2 PF13409.6 EON97617.1 - 2.2e-22 79.1 0.2 8.2e-22 77.3 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EON97617.1 - 7.4e-14 51.5 0.0 1.7e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EON97617.1 - 7.1e-06 26.4 0.0 0.00017 21.9 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EON97617.1 - 1.5e-05 25.1 0.0 4e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EON97617.1 - 0.00047 20.3 0.0 0.0011 19.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PhetRS_B1 PF18262.1 EON97617.1 - 0.0073 16.5 0.1 0.014 15.6 0.1 1.4 1 0 0 1 1 1 1 Phe-tRNA synthetase beta subunit B1 domain Tropomyosin_1 PF12718.7 EON97617.1 - 0.13 12.4 0.2 0.21 11.8 0.2 1.2 1 0 0 1 1 1 0 Tropomyosin like Aldo_ket_red PF00248.21 EON97618.1 - 2.7e-38 131.9 0.1 3.7e-37 128.1 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family GHMP_kinases_N PF00288.26 EON97620.1 - 2.8e-15 56.3 0.0 6.1e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EON97620.1 - 2.7e-09 37.3 0.0 6.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EON97620.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Arylsulfotran_2 PF14269.6 EON97621.1 - 9.7e-35 120.4 0.1 1.4e-22 80.5 0.4 2.2 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EON97621.1 - 6.3e-07 28.6 0.1 5e-06 25.7 0.2 2.2 2 1 0 2 2 2 1 Arylsulfotransferase (ASST) DUF5305 PF17231.2 EON97622.1 - 0.00077 18.9 0.2 0.0031 16.9 0.1 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5305) DUF4366 PF14283.6 EON97622.1 - 0.016 15.3 1.7 0.049 13.7 1.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) PTP_tm PF18861.1 EON97622.1 - 0.023 14.7 0.0 0.071 13.1 0.0 1.8 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Stevor PF17410.2 EON97622.1 - 0.044 13.3 0.7 0.076 12.5 0.7 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Orf78 PF06024.12 EON97622.1 - 0.044 14.1 0.4 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Orf78 (ac78) DUF4448 PF14610.6 EON97622.1 - 0.045 13.5 0.1 0.064 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SKG6 PF08693.10 EON97622.1 - 0.05 13.0 2.5 0.15 11.5 1.5 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain CD34_antigen PF06365.12 EON97622.1 - 0.083 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Amnionless PF14828.6 EON97622.1 - 0.097 11.5 0.5 0.15 10.9 0.5 1.2 1 0 0 1 1 1 0 Amnionless LapA_dom PF06305.11 EON97622.1 - 0.16 11.8 0.3 4.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4293 PF14126.6 EON97622.1 - 0.17 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) RIFIN PF02009.16 EON97622.1 - 0.46 10.3 4.0 1.2 8.9 4.0 1.6 1 1 0 1 1 1 0 Rifin Gram_pos_anchor PF00746.21 EON97622.1 - 0.64 10.0 5.2 0.81 9.7 0.4 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Podoplanin PF05808.11 EON97622.1 - 0.87 9.7 23.6 12 6.0 21.7 2.7 2 1 0 2 2 2 0 Podoplanin DUF4512 PF14975.6 EON97622.1 - 1.8 9.4 10.5 0.086 13.6 2.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) DUF2613 PF11021.8 EON97622.1 - 4.8 7.4 15.8 3.3 7.9 2.9 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2613) RhoGAP PF00620.27 EON97623.1 - 3.1e-46 157.0 0.1 3.1e-46 157.0 0.1 2.6 2 2 0 2 2 2 1 RhoGAP domain IFT20 PF14931.6 EON97623.1 - 0.57 10.4 12.7 0.075 13.2 5.2 2.5 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF4407 PF14362.6 EON97623.1 - 1.5 8.1 10.1 2.6 7.3 10.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 EON97623.1 - 1.5 9.3 15.9 11 6.5 15.9 2.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Fez1 PF06818.15 EON97623.1 - 2.2 8.7 14.2 4.9 7.6 14.2 1.5 1 0 0 1 1 1 0 Fez1 GIT_CC PF16559.5 EON97623.1 - 2.4 8.1 7.4 6.4 6.7 0.4 3.4 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_TATA_bd PF12325.8 EON97623.1 - 2.6 8.3 14.1 0.99 9.6 5.1 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.9 EON97623.1 - 4.4 6.3 8.7 9 5.3 8.3 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.9 EON97623.1 - 4.4 7.5 15.8 2.4 8.4 5.5 2.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Tim54 PF11711.8 EON97624.1 - 2.9e-140 467.3 3.3 2.9e-93 312.6 0.1 2.0 1 1 1 2 2 2 2 Inner membrane protein import complex subunit Tim54 Iso_dh PF00180.20 EON97625.1 - 8.6e-99 331.0 0.0 1.1e-98 330.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 EON97625.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 RRM_1 PF00076.22 EON97626.1 - 1.3e-08 34.5 0.0 1e-06 28.5 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SnoaL_2 PF12680.7 EON97627.1 - 1.5e-07 32.0 0.2 1.8e-07 31.7 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 EON97627.1 - 0.00039 20.7 0.1 0.00052 20.3 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EON97627.1 - 0.0011 19.3 0.1 0.0014 19.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 EON97627.1 - 0.0037 17.4 0.0 0.0066 16.6 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain UCH PF00443.29 EON97628.1 - 3.5e-33 115.2 0.0 6.8e-33 114.2 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EON97628.1 - 1e-05 25.3 0.0 0.00027 20.7 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L38e PF01781.18 EON97629.1 - 1e-32 112.0 5.6 1.3e-32 111.7 5.6 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Cyclophil_like2 PF18050.1 EON97629.1 - 0.023 14.6 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Cyclophilin-like family WD40 PF00400.32 EON97630.1 - 8.2e-12 45.5 2.3 0.00027 21.7 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON97630.1 - 0.0022 18.2 0.1 6.8 7.1 0.0 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EON97630.1 - 0.009 15.0 0.0 2.3 7.1 0.0 2.4 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2252 PF10009.9 EON97630.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) MFS_1 PF07690.16 EON97631.1 - 2.4e-27 95.8 26.3 6.9e-27 94.3 24.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 EON97632.1 - 2.8e-36 125.1 0.0 7e-36 123.9 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain YvbH_ext PF11724.8 EON97632.1 - 0.078 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 YvbH-like oligomerisation region Glyco_hydro_18 PF00704.28 EON97633.1 - 6.2e-16 59.0 1.3 3.2e-15 56.7 1.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.25 EON97634.1 - 3.8e-70 236.3 0.0 5.2e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON97634.1 - 1.7e-33 116.0 0.0 2.4e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EON97634.1 - 8.2e-13 48.8 2.7 1e-12 48.5 1.3 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EON97634.1 - 3.3e-06 26.3 0.1 4.8e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 EON97634.1 - 0.0029 17.9 0.0 0.007 16.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 EON97634.1 - 0.015 14.6 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 EON97634.1 - 0.07 12.7 0.1 0.85 9.2 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EON97634.1 - 0.16 11.3 0.1 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans PF04082.18 EON97635.1 - 1.1e-21 77.1 0.0 1.9e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EON97635.1 - 6.6e-09 35.8 11.4 1.2e-08 35.0 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TEX15 PF15326.6 EON97635.1 - 0.15 11.8 0.1 0.24 11.1 0.1 1.2 1 0 0 1 1 1 0 Testis expressed sequence 15 Taxilin PF09728.9 EON97636.1 - 5.7e-93 311.5 69.9 9.4e-93 310.8 69.9 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein TMF_TATA_bd PF12325.8 EON97636.1 - 0.002 18.3 65.3 0.66 10.2 12.0 4.5 2 2 2 4 4 4 4 TATA element modulatory factor 1 TATA binding SurA_N_2 PF13623.6 EON97637.1 - 0.025 14.5 1.2 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 SurA N-terminal domain DUF21 PF01595.20 EON97637.1 - 0.77 9.4 8.4 1.3 8.7 8.4 1.3 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain TF_Otx PF03529.13 EON97637.1 - 1.6 9.2 6.7 0.77 10.2 1.9 2.3 2 0 0 2 2 2 0 Otx1 transcription factor M16C_assoc PF08367.11 EON97638.1 - 7.3e-85 284.1 0.1 1.1e-84 283.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EON97638.1 - 1.7e-30 106.4 0.0 1.3e-20 74.2 0.0 3.2 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EON97638.1 - 2.1e-08 34.3 0.0 2.2e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) UvrA_inter PF17760.1 EON97638.1 - 0.13 12.3 0.1 1.6 8.8 0.1 2.3 2 0 0 2 2 2 0 UvrA interaction domain HHH_8 PF14716.6 EON97638.1 - 0.14 12.6 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain DAO PF01266.24 EON97639.1 - 1.2e-68 232.4 1.3 1.4e-68 232.1 1.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON97639.1 - 4.6e-06 26.1 2.6 0.011 15.0 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON97639.1 - 9e-06 26.2 0.3 0.15 12.6 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON97639.1 - 6.2e-05 23.2 0.4 0.00018 21.7 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 EON97639.1 - 0.00022 20.2 2.1 0.26 10.0 0.3 2.1 2 0 0 2 2 2 2 MCRA family Trp_halogenase PF04820.14 EON97639.1 - 0.0004 19.4 2.1 0.0013 17.7 0.3 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Amino_oxidase PF01593.24 EON97639.1 - 0.0019 17.5 0.2 0.0033 16.8 0.2 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase GMC_oxred_N PF00732.19 EON97639.1 - 0.0023 17.4 0.2 0.23 10.8 0.1 2.2 2 0 0 2 2 2 1 GMC oxidoreductase Mqo PF06039.15 EON97639.1 - 0.0031 16.1 0.1 0.76 8.3 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Sacchrp_dh_NADP PF03435.18 EON97639.1 - 0.0042 17.4 0.3 0.022 15.0 0.1 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 EON97639.1 - 0.02 14.2 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Vut_1 PF02592.15 EON97641.1 - 0.4 11.0 5.5 1 9.7 0.1 2.7 3 1 0 3 3 3 0 Putative vitamin uptake transporter Brix PF04427.18 EON97642.1 - 6.6e-48 163.4 0.0 1.1e-47 162.6 0.0 1.4 1 0 0 1 1 1 1 Brix domain CNDH2_C PF16858.5 EON97642.1 - 0.043 13.7 10.2 0.061 13.2 10.2 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Vfa1 PF08432.10 EON97642.1 - 1.5 9.1 11.9 3.2 8.0 11.9 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PPL5 PF18168.1 EON97642.1 - 8.7 5.5 11.0 5.3 6.2 8.9 1.6 2 0 0 2 2 2 0 Prim-pol family 5 Abhydrolase_6 PF12697.7 EON97643.1 - 1.1e-18 68.7 8.6 1.3e-18 68.4 8.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON97643.1 - 8.6e-17 61.6 0.2 1.7e-14 54.1 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON97643.1 - 1.1e-16 60.9 0.1 2.1e-16 59.9 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 EON97643.1 - 0.0004 19.0 0.0 0.0027 16.3 0.0 1.9 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_4 PF08386.10 EON97643.1 - 0.003 17.6 0.0 0.0053 16.8 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Ndr PF03096.14 EON97643.1 - 0.018 13.8 0.0 3.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Ndr family Abhydrolase_3 PF07859.13 EON97643.1 - 0.022 14.6 0.9 0.48 10.3 0.9 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EON97643.1 - 0.041 13.5 0.3 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 EON97643.1 - 0.14 12.0 0.1 0.71 9.6 0.1 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Bac_rhamnosid6H PF17389.2 EON97644.1 - 1.6e-92 310.4 0.1 2e-92 310.1 0.1 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 EON97644.1 - 7.1e-56 188.7 0.0 1.1e-55 188.1 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid_C PF17390.2 EON97644.1 - 4.2e-17 61.7 0.0 2.1e-16 59.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid PF05592.11 EON97644.1 - 3.9e-16 58.9 0.0 7e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain SRP68 PF16969.5 EON97645.1 - 1.9e-210 700.7 8.5 2.1e-210 700.5 8.5 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 Peptidase_S39 PF02122.15 EON97645.1 - 0.031 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase S39 Cytochrom_B562 PF07361.11 EON97645.1 - 0.42 11.3 2.1 11 6.7 0.4 2.9 2 0 0 2 2 2 0 Cytochrome b562 MFS_1 PF07690.16 EON97646.1 - 9.9e-23 80.6 18.8 9.9e-23 80.6 18.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily CPP1-like PF11833.8 EON97646.1 - 0.17 11.6 4.8 6.4 6.4 0.0 2.6 1 1 2 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like TPT PF03151.16 EON97650.1 - 7.2e-16 58.4 13.6 1e-15 57.9 13.6 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EON97650.1 - 0.0038 17.4 27.2 0.096 12.9 15.0 2.8 3 0 0 3 3 3 2 EamA-like transporter family DUF2070 PF09843.9 EON97650.1 - 0.46 8.7 12.3 0.7 8.1 12.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ras PF00071.22 EON97651.1 - 3.9e-39 133.8 0.0 7.5e-37 126.4 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EON97651.1 - 3.5e-30 104.7 0.0 4.9e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EON97651.1 - 2.5e-09 36.8 0.0 3.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EON97651.1 - 0.00054 20.0 0.0 0.00089 19.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EON97651.1 - 0.02 14.3 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EON97651.1 - 0.021 15.2 0.0 0.032 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EON97651.1 - 0.047 13.7 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EON97651.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DLIC PF05783.11 EON97651.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RTP1_C2 PF10304.9 EON97651.1 - 0.16 11.7 0.3 0.28 10.9 0.3 1.4 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 AAA_28 PF13521.6 EON97651.1 - 0.49 10.6 1.9 0.94 9.7 0.1 2.2 3 0 0 3 3 3 0 AAA domain DAO PF01266.24 EON97652.1 - 1.2e-60 206.0 1.9 1.3e-60 205.8 1.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.15 EON97652.1 - 0.0011 17.6 0.1 1.5 7.3 0.1 2.7 3 0 0 3 3 3 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.6 EON97652.1 - 0.0019 18.4 0.8 0.0046 17.1 0.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EON97652.1 - 0.0043 16.3 0.7 0.4 9.9 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EON97652.1 - 0.032 13.5 0.1 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EON97652.1 - 0.035 13.3 0.1 0.07 12.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 EON97652.1 - 0.05 12.9 2.3 0.42 9.9 2.3 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EON97652.1 - 0.3 10.1 0.6 0.58 9.1 0.6 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EON97652.1 - 1 8.4 4.5 1.4 7.9 4.5 1.3 1 1 0 1 1 1 0 FAD binding domain Aldo_ket_red PF00248.21 EON97653.1 - 0.00048 19.4 0.0 0.00061 19.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ammonium_transp PF00909.21 EON97654.1 - 1.3e-70 238.1 29.5 1.5e-70 238.0 29.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Glyco_transf_22 PF03901.17 EON97655.1 - 5.1e-84 282.9 9.3 5.9e-84 282.7 9.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family CBS PF00571.28 EON97656.1 - 6.4e-25 87.4 8.0 5.3e-11 42.8 0.4 4.3 4 0 0 4 4 4 4 CBS domain GSHPx PF00255.19 EON97657.1 - 3e-41 139.4 0.1 3.8e-41 139.0 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 EON97657.1 - 0.00022 21.0 0.0 0.00049 19.8 0.0 1.6 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.21 EON97657.1 - 0.00054 19.9 0.1 0.0013 18.7 0.0 1.7 2 1 0 2 2 2 1 AhpC/TSA family DUF4174 PF13778.6 EON97657.1 - 0.01 16.3 0.0 0.021 15.3 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4174) TIMELESS PF04821.14 EON97658.1 - 9.4e-87 290.8 1.1 1.7e-86 289.9 0.1 2.1 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 EON97658.1 - 2.7e-33 116.0 36.2 2.7e-33 116.0 36.2 3.8 2 1 0 2 2 2 1 Timeless protein C terminal region LacAB_rpiB PF02502.18 EON97659.1 - 3.2e-43 147.1 0.3 3.7e-43 146.9 0.3 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Acetyltransf_1 PF00583.25 EON97660.1 - 2e-10 40.9 0.0 2.5e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EON97660.1 - 1.3e-08 34.9 0.0 1.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EON97660.1 - 5e-06 26.9 0.0 8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EON97660.1 - 0.0013 18.8 0.1 0.01 15.9 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EON97660.1 - 0.17 11.9 0.0 0.39 10.7 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein WSC PF01822.19 EON97661.1 - 2.8e-21 75.5 17.2 1.3e-17 63.7 12.1 2.1 2 0 0 2 2 2 2 WSC domain PRKCSH_1 PF13015.6 EON97661.1 - 0.063 13.0 1.3 1 9.0 0.4 2.3 2 1 0 2 2 2 0 Glucosidase II beta subunit-like protein Glycos_transf_4 PF00953.21 EON97662.1 - 5.9e-31 107.6 13.4 5.9e-31 107.6 13.4 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF1754 PF08555.10 EON97663.1 - 4.4e-11 43.4 18.2 7.1e-11 42.8 18.2 1.4 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) MSA_2 PF00985.17 EON97663.1 - 0.017 15.5 4.9 0.023 15.0 4.9 1.2 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family CDC27 PF09507.10 EON97663.1 - 0.042 13.2 17.6 0.048 13.1 17.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Glutaredoxin2_C PF04399.13 EON97663.1 - 0.13 12.1 0.5 0.24 11.2 0.5 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain HCO3_cotransp PF00955.21 EON97664.1 - 3.2e-86 290.2 12.8 7.1e-46 157.1 6.7 2.0 1 1 1 2 2 2 2 HCO3- transporter family TNFR_16_TM PF18422.1 EON97664.1 - 0.051 13.5 0.6 0.24 11.4 0.6 2.2 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain SBD_N PF07005.11 EON97665.1 - 9.7e-63 211.9 0.1 1.4e-62 211.4 0.1 1.2 1 0 0 1 1 1 1 Sugar-binding N-terminal domain NBD_C PF17042.5 EON97665.1 - 6.8e-42 143.9 0.1 1.6e-41 142.6 0.0 1.7 2 0 0 2 2 2 1 Nucleotide-binding C-terminal domain MCPsignal PF00015.21 EON97665.1 - 0.0053 16.6 0.9 0.01 15.7 0.9 1.4 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1561 PF07598.11 EON97665.1 - 0.063 11.5 0.0 0.086 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) NARP1 PF12569.8 EON97666.1 - 2.3e-196 653.7 30.1 5.8e-196 652.4 19.4 2.6 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.6 EON97666.1 - 1.4e-16 60.8 27.5 0.0022 18.6 0.0 9.5 8 1 1 9 9 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EON97666.1 - 1.9e-16 59.3 20.2 0.014 16.2 0.0 11.0 7 4 5 12 12 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 EON97666.1 - 8.7e-16 58.2 32.3 0.0017 18.8 0.1 8.7 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 EON97666.1 - 1e-15 56.5 31.4 0.00062 19.7 0.1 11.4 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_11 PF13414.6 EON97666.1 - 9.3e-13 47.6 13.4 0.0006 19.4 0.0 6.2 6 0 0 6 6 5 4 TPR repeat TPR_17 PF13431.6 EON97666.1 - 8.4e-11 41.5 13.9 0.0032 17.8 0.0 8.4 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EON97666.1 - 1.2e-10 41.4 12.3 0.003 17.8 0.8 5.4 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EON97666.1 - 3e-10 40.1 10.3 0.0022 18.1 0.3 6.3 5 2 1 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EON97666.1 - 1.8e-09 37.5 8.8 0.07 13.2 0.1 6.0 6 0 0 6 6 5 4 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 EON97666.1 - 2.1e-09 37.5 18.7 0.019 15.2 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 EON97666.1 - 5e-09 35.6 30.7 3.8e-05 23.3 0.2 8.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 EON97666.1 - 5.9e-08 32.3 22.5 0.00053 20.0 0.1 8.1 9 0 0 9 9 8 3 Tetratricopeptide repeat DUF913 PF06025.12 EON97666.1 - 0.0069 15.4 0.6 0.013 14.5 0.6 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) TPR_10 PF13374.6 EON97666.1 - 0.018 14.9 13.2 3.7 7.6 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 EON97666.1 - 0.02 14.9 1.8 1.3 9.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EON97666.1 - 0.2 12.4 17.2 24 5.8 1.8 7.4 8 1 0 8 8 6 0 Tetratricopeptide repeat Presenilin PF01080.17 EON97666.1 - 2.2 6.9 4.2 4.1 6.1 4.2 1.3 1 0 0 1 1 1 0 Presenilin TPR_4 PF07721.14 EON97666.1 - 4.5 8.2 10.8 3.9 8.4 0.2 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EON97666.1 - 7.6 7.0 13.6 42 4.6 0.1 5.0 5 0 0 5 5 5 0 Alkyl sulfatase dimerisation adh_short PF00106.25 EON97667.1 - 1.8e-23 83.1 0.0 4.3e-19 68.7 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON97667.1 - 3.2e-13 49.8 0.0 2.4e-12 46.9 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON97667.1 - 1.2e-06 28.5 0.1 3.1e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 KR domain PEMT PF04191.13 EON97668.1 - 5.2e-57 190.8 8.6 5.4e-36 123.2 0.8 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase HEAT_2 PF13646.6 EON97668.1 - 2.9e-25 88.5 5.7 7.8e-12 45.4 0.4 3.7 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 EON97668.1 - 2.9e-16 58.4 3.9 0.051 14.3 0.2 6.8 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EON97668.1 - 0.0022 18.1 6.2 6.9 7.2 0.0 6.0 6 0 0 6 6 6 1 HEAT repeat HECW_N PF16562.5 EON97668.1 - 0.014 15.2 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 HEAT_EZ PF13513.6 EON97668.1 - 7.3 7.2 8.7 6.4 7.4 0.1 4.3 4 1 1 5 5 5 0 HEAT-like repeat rRNA_processing PF08524.11 EON97669.1 - 0.00017 21.6 31.6 0.058 13.4 31.6 2.1 1 1 0 1 1 1 1 rRNA processing Chitin_synth_2 PF03142.15 EON97670.1 - 3.5e-252 837.7 1.8 8.6e-252 836.4 2.1 1.4 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.21 EON97670.1 - 6.1e-72 242.9 0.0 7.6e-71 239.3 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 EON97670.1 - 3e-17 62.3 0.0 1.3e-16 60.2 0.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 EON97670.1 - 4.3e-14 52.4 0.4 2.1e-10 40.6 0.1 3.0 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 EON97670.1 - 6.7e-12 45.7 6.0 6.7e-12 45.7 6.0 2.0 2 0 0 2 2 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EON97670.1 - 1.3e-10 41.6 0.1 9.9e-10 38.7 0.1 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EON97670.1 - 1.6e-05 24.8 0.0 0.013 15.3 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_16 PF13191.6 EON97670.1 - 0.0095 16.3 0.2 0.034 14.5 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain DUF1622 PF07784.11 EON97670.1 - 0.027 14.4 0.7 14 5.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1622) AAA_7 PF12775.7 EON97670.1 - 0.036 13.6 0.1 0.078 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 EON97670.1 - 0.06 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 EON97670.1 - 0.072 13.4 0.3 0.28 11.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain Glyco_transf_21 PF13506.6 EON97670.1 - 0.078 12.4 0.4 0.41 10.1 0.4 2.1 1 1 0 1 1 1 0 Glycosyl transferase family 21 AAA_29 PF13555.6 EON97670.1 - 0.14 11.9 0.1 0.43 10.3 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.10 EON97670.1 - 0.16 11.4 0.5 0.58 9.6 0.5 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit GFO_IDH_MocA PF01408.22 EON97671.1 - 2.1e-11 44.7 1.8 1.1e-10 42.4 1.8 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EON97671.1 - 0.0064 17.1 0.1 0.015 16.0 0.1 1.7 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain PNTB PF02233.16 EON97672.1 - 2.2e-160 534.5 27.5 2.2e-160 534.5 27.5 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EON97672.1 - 7.5e-74 247.6 1.4 8.7e-74 247.4 0.1 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EON97672.1 - 9.5e-50 168.4 0.3 2.2e-49 167.2 0.1 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EON97672.1 - 1.7e-29 102.1 2.4 1.7e-29 102.1 2.4 5.7 4 2 0 5 5 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EON97672.1 - 0.0034 16.8 0.1 1 8.7 0.0 3.2 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 EON97672.1 - 0.004 17.1 0.1 0.031 14.2 0.1 2.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 EON97672.1 - 0.014 14.7 0.1 0.029 13.6 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 EON97672.1 - 0.094 12.4 0.3 0.81 9.4 0.4 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fumerase PF05681.14 EON97672.1 - 0.13 11.6 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) AcetylCoA_hyd_C PF13336.6 EON97672.1 - 0.14 12.1 0.3 9.6 6.1 0.4 2.4 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain Git3 PF11710.8 EON97672.1 - 0.45 10.3 1.6 0.43 10.3 0.2 1.6 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 NAD_binding_8 PF13450.6 EON97672.1 - 7.6 6.8 9.3 1.2 9.5 2.9 3.1 3 1 0 3 3 2 0 NAD(P)-binding Rossmann-like domain DUF2235 PF09994.9 EON97673.1 - 4.3e-40 137.9 0.2 5e-40 137.7 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Methyltransf_16 PF10294.9 EON97674.1 - 8e-11 42.0 0.0 1.6e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase SLC12 PF03522.15 EON97675.1 - 2e-12 46.9 0.1 2.3e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 Solute carrier family 12 SAP130_C PF16014.5 EON97675.1 - 0.084 12.0 0.5 0.12 11.5 0.5 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus 3HCDH_N PF02737.18 EON97677.1 - 7.4e-19 68.3 0.0 1.2e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EON97677.1 - 9.5e-14 51.8 0.0 1.6e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF1772 PF08592.11 EON97678.1 - 0.00017 22.0 8.7 0.00064 20.0 8.7 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) FAD_binding_2 PF00890.24 EON97680.1 - 9.9e-40 136.9 0.0 3.4e-39 135.1 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EON97680.1 - 1.3e-12 48.0 1.4 1.1e-11 44.9 1.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EON97680.1 - 1.3e-10 41.3 1.3 1.9e-10 40.7 1.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EON97680.1 - 3.2e-07 29.4 1.0 8.2e-06 24.8 0.2 2.5 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_2 PF07992.14 EON97680.1 - 1.9e-05 24.1 0.3 9.6e-05 21.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON97680.1 - 6.5e-05 23.1 2.6 0.00018 21.7 2.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EON97680.1 - 6.7e-05 22.1 7.9 0.00053 19.2 6.9 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EON97680.1 - 0.001 19.6 1.2 0.24 12.0 1.4 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EON97680.1 - 0.0049 16.1 4.2 0.0093 15.2 4.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 EON97680.1 - 0.005 16.1 0.9 0.018 14.3 0.7 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EON97680.1 - 0.0055 16.0 1.3 0.012 14.9 1.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EON97680.1 - 0.039 13.2 6.5 0.33 10.2 4.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EON97680.1 - 4.7 6.1 6.9 2.8 6.9 3.1 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein Alk_phosphatase PF00245.20 EON97681.1 - 3.3e-66 224.0 0.0 1.5e-65 221.8 0.0 1.8 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 EON97681.1 - 6.3e-06 25.8 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EON97681.1 - 9e-06 25.5 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EON97681.1 - 0.014 14.0 0.2 0.024 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF1501 PF07394.12 EON97681.1 - 0.18 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) GMC_oxred_N PF00732.19 EON97682.1 - 2.8e-25 89.3 0.0 3.4e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 EON97682.1 - 0.0011 18.3 0.3 0.0024 17.2 0.0 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EON97682.1 - 0.0045 17.2 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EON97682.1 - 0.033 13.3 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 EON97682.1 - 0.034 13.7 0.0 0.066 12.8 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EON97682.1 - 0.06 12.4 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EON97682.1 - 0.12 11.6 0.1 0.17 11.1 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EON97682.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 EON97682.1 - 0.14 10.9 0.0 0.24 10.0 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_4 PF01565.23 EON97683.1 - 3e-36 124.2 4.1 3e-36 124.2 4.1 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EON97683.1 - 2.3e-05 24.4 0.3 5.2e-05 23.3 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_76 PF03663.14 EON97684.1 - 5.5e-139 463.7 12.0 6.4e-139 463.5 12.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EON97684.1 - 0.75 8.8 10.3 0.57 9.2 0.4 3.2 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 DNA_pol3_alpha PF07733.12 EON97685.1 - 0.3 10.7 6.3 0.38 10.3 6.3 1.1 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha NTPase domain BSP PF04450.12 EON97687.1 - 2.9e-80 269.0 0.0 3.4e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_M91 PF14891.6 EON97687.1 - 0.051 13.9 0.0 0.089 13.1 0.0 1.4 1 0 0 1 1 1 0 Effector protein Amidohydro_1 PF01979.20 EON97688.1 - 2.6e-79 267.0 0.0 3e-79 266.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EON97688.1 - 6.9e-11 42.3 1.5 1.2e-08 34.9 0.1 2.1 1 1 0 2 2 2 2 Amidohydrolase family Ribosomal_S17e PF00833.18 EON97689.1 - 5.5e-60 200.7 0.4 6.6e-60 200.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S17 DUF1757 PF08560.10 EON97690.1 - 0.017 15.2 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) PhoLip_ATPase_C PF16212.5 EON97691.1 - 4.3e-76 256.0 16.9 4.3e-76 256.0 16.9 1.6 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EON97691.1 - 4.1e-13 50.1 0.0 5.2e-06 26.9 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EON97691.1 - 1.8e-12 47.2 0.0 7.9e-11 41.9 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EON97691.1 - 7e-10 38.7 0.1 7e-10 38.7 0.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EON97691.1 - 0.00038 20.3 0.0 0.002 17.9 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EON97691.1 - 0.02 15.0 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DctQ PF04290.12 EON97691.1 - 2.2 8.2 10.0 0.052 13.5 0.6 2.6 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Methyltransf_2 PF00891.18 EON97692.1 - 8.4e-21 74.2 0.0 1.2e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 EON97692.1 - 0.0045 17.0 0.0 0.054 13.5 0.0 2.3 2 0 0 2 2 2 1 Dimerisation domain TIM PF00121.18 EON97693.1 - 4.6e-51 173.5 0.0 5.3e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase p450 PF00067.22 EON97694.1 - 8.6e-34 117.1 0.0 1.1e-33 116.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SR-25 PF10500.9 EON97695.1 - 0.0065 16.1 8.9 0.013 15.1 8.9 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein GATA PF00320.27 EON97695.1 - 0.014 15.0 0.6 0.014 15.0 0.6 2.2 2 0 0 2 2 2 0 GATA zinc finger AMP_N PF05195.16 EON97695.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain DUF4428 PF14471.6 EON97695.1 - 0.12 12.3 1.1 0.35 10.8 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) AAA_23 PF13476.6 EON97695.1 - 0.73 10.3 6.6 1.6 9.2 6.6 1.5 1 0 0 1 1 1 0 AAA domain Paramyxo_ncap PF00973.19 EON97695.1 - 7.4 5.4 9.9 12 4.7 9.9 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Metallophos PF00149.28 EON97696.1 - 1.5e-07 32.1 6.7 7e-07 30.0 6.7 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EON97696.1 - 0.00014 22.1 1.5 0.00035 20.8 1.5 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cu-oxidase PF00394.22 EON97697.1 - 2.1e-32 112.4 0.1 8.1e-32 110.5 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EON97697.1 - 5.5e-14 52.2 1.0 3.3e-13 49.7 0.2 2.3 2 0 0 2 2 2 1 Multicopper oxidase DNA_pol_A_exo1 PF01612.20 EON97699.1 - 1.6e-14 54.0 0.0 2.3e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Cyclase_polyket PF04673.12 EON97699.1 - 0.053 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Polyketide synthesis cyclase EF-hand_7 PF13499.6 EON97700.1 - 3.3e-25 88.3 8.9 2.8e-16 59.7 1.3 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EON97700.1 - 1.5e-24 83.7 5.1 3.8e-06 26.4 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_1 PF00036.32 EON97700.1 - 3e-24 82.7 14.3 3.2e-08 32.5 0.2 4.8 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 EON97700.1 - 2.6e-17 61.5 14.1 3.8e-05 23.0 0.1 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 EON97700.1 - 6.6e-14 51.5 13.0 3e-05 23.8 1.0 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EON97700.1 - 3.8e-09 36.4 8.5 0.0046 16.9 0.2 4.0 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EON97700.1 - 5.7e-05 23.4 0.7 0.0086 16.4 0.1 2.9 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EON97700.1 - 0.00076 19.8 3.6 0.84 10.0 0.5 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 EON97700.1 - 0.02 13.8 0.6 2 7.2 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) Staphylokinase PF02821.16 EON97700.1 - 0.08 13.4 0.0 20 5.6 0.0 2.5 1 1 1 2 2 2 0 Staphylokinase/Streptokinase family EF-hand_14 PF17959.1 EON97700.1 - 0.13 12.6 3.1 6.8 7.1 0.0 3.6 3 1 0 3 3 3 0 EF-hand domain EF-hand_10 PF14788.6 EON97700.1 - 0.19 11.6 5.7 0.44 10.4 0.1 3.6 5 0 0 5 5 5 0 EF hand Caleosin PF05042.13 EON97700.1 - 0.23 11.4 2.7 36 4.2 0.0 3.5 2 1 2 4 4 4 0 Caleosin related protein BRE PF06113.12 EON97701.1 - 0.014 14.3 0.1 0.023 13.6 0.1 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) peroxidase PF00141.23 EON97702.1 - 2.4e-19 69.9 0.0 4e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4246 PF14033.6 EON97703.1 - 3.4e-183 609.9 2.7 4.1e-183 609.6 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EON97703.1 - 0.0082 16.5 0.0 0.049 14.0 0.0 2.2 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase HSP70 PF00012.20 EON97704.1 - 9.7e-08 30.7 0.0 2.3e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EON97704.1 - 0.083 11.7 0.1 0.17 10.7 0.1 1.5 1 0 0 1 1 1 0 MreB/Mbl protein HAD_2 PF13419.6 EON97705.1 - 1.7e-13 51.1 0.0 7e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EON97705.1 - 7.5e-07 29.6 0.0 3.2e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EON97705.1 - 0.002 18.1 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Porphobil_deam PF01379.20 EON97706.1 - 2.2e-72 242.9 0.0 2.9e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EON97706.1 - 1.2e-17 64.1 0.1 2.2e-17 63.2 0.1 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain F-box-like PF12937.7 EON97707.1 - 0.015 15.2 0.7 0.04 13.8 0.7 1.8 1 0 0 1 1 1 0 F-box-like RIBIOP_C PF04950.12 EON97708.1 - 3.2e-94 315.6 0.1 3.2e-94 315.6 0.1 2.2 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EON97708.1 - 8.3e-28 96.3 0.1 3.8e-27 94.2 0.0 2.3 3 0 0 3 3 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 EON97708.1 - 4.1e-05 23.9 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EON97708.1 - 8.6e-05 23.0 0.0 0.00027 21.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EON97708.1 - 0.00039 21.0 1.2 0.0023 18.4 0.0 2.8 3 0 0 3 3 2 1 ABC transporter AAA PF00004.29 EON97708.1 - 0.00057 20.3 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EON97708.1 - 0.00065 19.7 0.0 0.0017 18.3 0.0 1.8 1 1 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.23 EON97708.1 - 0.00084 19.4 0.1 0.0028 17.7 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EON97708.1 - 0.00084 18.9 1.3 0.09 12.3 0.0 2.7 2 1 1 3 3 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 EON97708.1 - 0.0011 19.1 0.4 0.0035 17.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain PduV-EutP PF10662.9 EON97708.1 - 0.0024 17.7 0.0 0.0062 16.3 0.0 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 EON97708.1 - 0.006 16.9 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 EON97708.1 - 0.0097 15.8 0.5 0.54 10.2 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 EON97708.1 - 0.012 14.8 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 EON97708.1 - 0.013 16.1 13.6 0.042 14.4 0.0 4.4 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 EON97708.1 - 0.013 15.9 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EON97708.1 - 0.014 15.4 0.4 0.042 13.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 EON97708.1 - 0.014 15.1 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EON97708.1 - 0.015 14.9 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 EON97708.1 - 0.023 14.9 0.0 0.077 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 EON97708.1 - 0.027 14.4 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_7 PF12775.7 EON97708.1 - 0.04 13.4 0.0 0.14 11.7 0.0 1.9 1 0 0 1 1 1 0 P-loop containing dynein motor region Roc PF08477.13 EON97708.1 - 0.048 13.9 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 EON97708.1 - 0.048 13.6 0.2 0.1 12.5 0.2 1.5 1 0 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 EON97708.1 - 0.051 13.5 0.0 0.21 11.5 0.0 2.0 1 0 0 1 1 1 0 RsgA GTPase SRPRB PF09439.10 EON97708.1 - 0.076 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 EON97708.1 - 0.079 13.0 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EON97708.1 - 0.084 12.4 0.0 0.28 10.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 EON97708.1 - 0.098 12.6 0.1 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain Wzy_C_2 PF11846.8 EON97708.1 - 0.22 11.5 0.4 0.4 10.6 0.4 1.3 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal Ank_5 PF13857.6 EON97709.1 - 8.5e-11 41.9 0.0 5e-07 29.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EON97709.1 - 5.9e-05 23.5 0.0 0.00027 21.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EON97709.1 - 0.0003 21.3 0.0 0.00067 20.2 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EON97709.1 - 0.0063 16.9 0.0 0.042 14.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat DNA_ligase_A_N PF04675.14 EON97709.1 - 0.031 14.6 0.0 0.044 14.1 0.0 1.2 1 0 0 1 1 1 0 DNA ligase N terminus GalKase_gal_bdg PF10509.9 EON97710.1 - 1.1e-21 76.1 0.1 2e-21 75.2 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EON97710.1 - 2.2e-13 50.2 1.6 6.7e-13 48.7 1.6 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EON97710.1 - 7.6e-13 48.6 0.1 2.6e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal GP57 PF17594.2 EON97710.1 - 0.023 14.4 0.1 0.22 11.3 0.0 2.5 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 HTH_23 PF13384.6 EON97710.1 - 0.15 11.9 0.0 0.41 10.5 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4 PF04545.16 EON97710.1 - 0.15 11.6 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 DUF1223 PF06764.11 EON97711.1 - 5.9e-54 183.2 0.0 7.2e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) SH3_9 PF14604.6 EON97712.1 - 0.032 14.1 0.0 0.59 10.0 0.0 2.8 2 1 0 2 2 2 0 Variant SH3 domain PWI PF01480.17 EON97713.1 - 1.2e-08 35.1 0.0 2.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 EON97713.1 - 4.8e-06 26.3 0.5 5.6e-05 22.9 0.2 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EON97713.1 - 6.8e-05 22.8 0.1 0.00099 19.1 0.1 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 EON97713.1 - 0.0016 18.4 3.4 0.0029 17.6 3.4 1.4 1 0 0 1 1 1 1 Zinc finger domain LRS4 PF10422.9 EON97713.1 - 0.018 14.6 2.7 0.03 13.9 2.7 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 RRM_occluded PF16842.5 EON97713.1 - 0.037 13.9 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif zf-CCCH PF00642.24 EON97713.1 - 0.097 12.6 3.5 0.17 11.8 3.5 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EON97713.1 - 4.3 8.1 5.5 0.7 10.6 0.2 2.2 2 0 0 2 2 2 0 Torus domain PHM7_cyt PF14703.6 EON97713.1 - 7.2 6.8 8.2 2.6 8.2 0.0 3.0 3 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 EON97713.1 - 7.6 6.6 9.8 13 5.9 0.0 3.3 3 0 0 3 3 3 0 RNA binding motif Pkinase PF00069.25 EON97714.1 - 1.8e-13 50.5 0.0 5.1e-13 49.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON97714.1 - 3.9e-09 36.2 0.0 0.00019 20.8 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EON97714.1 - 0.094 11.7 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1996 PF09362.10 EON97715.1 - 3.3e-72 243.3 3.7 4.4e-72 242.9 3.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Lys PF00062.20 EON97715.1 - 0.069 13.4 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family Aconitase PF00330.20 EON97717.1 - 5.4e-162 540.0 0.0 6.6e-162 539.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EON97717.1 - 5.9e-41 139.9 0.0 1.1e-40 139.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Amidohydro_1 PF01979.20 EON97719.1 - 1.1e-17 64.4 0.0 7.3e-16 58.4 0.0 2.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EON97719.1 - 1.7e-10 41.0 0.1 1.3e-05 24.9 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.20 EON97719.1 - 0.048 14.0 0.0 0.13 12.6 0.1 1.7 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain FKBP_C PF00254.28 EON97720.1 - 1.3e-27 95.9 0.0 1.7e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NMT1 PF09084.11 EON97721.1 - 1e-11 45.2 0.0 1.5e-11 44.7 0.0 1.3 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EON97721.1 - 0.0059 16.3 0.0 0.022 14.4 0.0 1.8 2 0 0 2 2 2 1 NMT1-like family Se-cys_synth_N PF12390.8 EON97721.1 - 0.29 11.4 1.8 98 3.3 0.1 3.5 4 0 0 4 4 4 0 Selenocysteine synthase N terminal AA_permease_2 PF13520.6 EON97722.1 - 1.7e-88 297.3 36.1 1.7e-88 297.3 36.1 1.2 1 1 0 1 1 1 1 Amino acid permease Nucleos_tra2_C PF07662.13 EON97723.1 - 4.4e-73 245.5 1.1 4.4e-73 245.5 1.1 2.6 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EON97723.1 - 1.3e-21 77.0 3.6 1.3e-21 77.0 3.6 2.6 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus ATP1G1_PLM_MAT8 PF02038.16 EON97723.1 - 2.6 7.5 5.4 2 7.9 2.8 2.1 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Gate PF07670.14 EON97723.1 - 8 6.8 16.2 0.99 9.7 7.9 3.3 2 1 0 2 2 2 0 Nucleoside recognition DbpA PF03880.15 EON97724.1 - 0.0018 18.2 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 DbpA RNA binding domain UPF0261 PF06792.11 EON97725.1 - 8.7e-143 476.1 0.1 9.8e-143 475.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) DUF2218 PF09981.9 EON97725.1 - 0.057 13.8 0.0 0.18 12.2 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) Kdo PF06293.14 EON97728.1 - 4.3e-07 29.5 0.0 7.9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EON97728.1 - 1.2e-06 28.6 0.7 0.00032 20.7 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 EON97728.1 - 1.2e-05 25.0 0.0 2.5e-05 24.0 0.0 1.4 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 EON97728.1 - 0.00073 19.2 0.5 0.41 10.2 0.2 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase Pkinase PF00069.25 EON97728.1 - 0.0072 15.7 0.0 0.021 14.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain WaaY PF06176.11 EON97728.1 - 0.043 13.4 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Cyto_heme_lyase PF01265.17 EON97729.1 - 4.4e-116 387.6 0.6 4.8e-116 387.4 0.6 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase PRKCSH-like PF12999.7 EON97730.1 - 5.9e-38 130.4 11.6 1.9e-22 79.9 0.7 3.3 4 1 0 4 4 4 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EON97730.1 - 5.5e-31 107.3 0.6 5.5e-31 107.3 0.6 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 EON97730.1 - 1.6e-10 41.9 1.1 4.7e-10 40.3 1.1 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DFF-C PF09033.10 EON97730.1 - 0.00021 21.2 3.6 0.00046 20.1 0.4 2.4 2 0 0 2 2 2 1 DNA Fragmentation factor 45kDa, C terminal domain DUF773 PF05600.12 EON97730.1 - 0.0025 16.6 3.0 0.0054 15.5 3.0 1.5 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 ATG27 PF09451.10 EON97730.1 - 0.016 15.1 0.7 0.016 15.1 0.7 2.1 2 0 0 2 2 2 0 Autophagy-related protein 27 Mod_r PF07200.13 EON97730.1 - 0.021 14.9 12.5 0.023 14.8 0.4 2.9 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Prefoldin_2 PF01920.20 EON97730.1 - 0.031 14.2 16.5 0.22 11.5 6.9 3.4 3 0 0 3 3 3 0 Prefoldin subunit FliD_C PF07195.12 EON97730.1 - 0.095 12.1 4.1 1.2 8.5 0.7 2.8 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Fib_alpha PF08702.10 EON97730.1 - 0.21 11.8 3.1 5 7.3 0.2 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 EON97730.1 - 0.21 12.1 4.8 0.39 11.2 0.1 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 EON97730.1 - 0.37 11.1 8.1 2 8.8 0.5 2.7 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Snapin_Pallidin PF14712.6 EON97730.1 - 0.49 10.8 7.8 0.9 10.0 0.1 3.2 3 0 0 3 3 3 0 Snapin/Pallidin Spc24 PF08286.11 EON97730.1 - 0.52 10.6 7.9 0.87 9.9 0.5 3.1 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 GAS PF13851.6 EON97730.1 - 0.69 9.2 15.7 0.055 12.8 5.4 2.4 3 0 0 3 3 2 0 Growth-arrest specific micro-tubule binding DUF684 PF05075.14 EON97730.1 - 1 8.3 3.9 0.23 10.4 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF684) Filament PF00038.21 EON97730.1 - 1.2 8.7 18.3 1.1 8.7 6.6 2.5 3 0 0 3 3 3 0 Intermediate filament protein DUF3584 PF12128.8 EON97730.1 - 2.1 5.7 15.5 0.066 10.7 9.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF4200 PF13863.6 EON97730.1 - 2.3 8.7 24.7 0.38 11.2 12.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.11 EON97730.1 - 2.4 8.8 8.4 35 5.0 0.2 3.2 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Sec34 PF04136.15 EON97730.1 - 3.5 7.5 6.1 16 5.4 0.0 2.6 3 0 0 3 3 3 0 Sec34-like family Rab5-bind PF09311.11 EON97730.1 - 5.1 6.4 13.3 0.26 10.7 3.9 2.4 3 0 0 3 3 3 0 Rabaptin-like protein YabA PF06156.13 EON97730.1 - 7 7.4 7.5 21 5.8 1.8 2.7 3 0 0 3 3 2 0 Initiation control protein YabA DUF4407 PF14362.6 EON97730.1 - 8.2 5.7 18.3 37 3.5 17.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) FliD_N PF02465.18 EON97730.1 - 9.3 7.0 7.6 51 4.7 0.1 3.2 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF2721 PF11026.8 EON97730.1 - 9.7 6.1 5.4 3.2 7.6 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Acetyltransf_3 PF13302.7 EON97731.1 - 3e-13 50.6 0.0 3.9e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON97731.1 - 6.5e-13 48.9 0.0 1e-12 48.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EON97731.1 - 1.1e-06 28.8 0.0 1.5e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EON97731.1 - 1.3e-06 28.7 0.0 1.9e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EON97731.1 - 0.00042 20.2 0.0 0.0016 18.4 0.0 1.9 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 EON97731.1 - 0.006 16.3 0.0 0.013 15.2 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MPLKIP PF15502.6 EON97731.1 - 0.025 14.8 0.2 0.058 13.6 0.2 1.6 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein PEP_hydrolase PF09370.10 EON97733.1 - 7.3e-136 451.6 0.5 8.3e-136 451.4 0.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NMO PF03060.15 EON97733.1 - 0.00015 21.2 0.2 0.00021 20.8 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase L_protein_N PF15518.6 EON97733.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 L protein N-terminus Pectate_lyase_3 PF12708.7 EON97734.1 - 6.1e-103 343.3 12.1 3.8e-88 294.9 1.5 2.9 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EON97734.1 - 1.8e-07 30.7 1.3 0.0098 15.6 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase RtxA PF07634.11 EON97734.1 - 0.013 16.0 0.9 8.2 7.2 0.0 3.8 3 0 0 3 3 3 0 RtxA repeat Aldo_ket_red PF00248.21 EON97735.1 - 1.2e-70 238.0 0.0 1.5e-70 237.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RhgB_N PF09284.10 EON97736.1 - 7.7e-73 245.1 0.3 7.7e-73 245.1 0.3 1.6 2 0 0 2 2 2 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 EON97736.1 - 1.8e-43 148.3 0.1 7.1e-43 146.3 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 EON97736.1 - 8e-24 83.2 7.1 8e-24 83.2 7.1 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 EON97736.1 - 0.0003 21.0 10.2 0.00043 20.5 5.6 3.0 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EON97736.1 - 0.0096 15.9 1.2 0.021 14.8 0.4 2.0 2 0 0 2 2 2 1 CarboxypepD_reg-like domain PEGA PF08308.11 EON97736.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 PEGA domain DUF2012 PF09430.10 EON97736.1 - 0.092 12.9 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) DUF1735 PF08522.10 EON97736.1 - 0.095 13.3 1.4 3.2 8.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1735) Sugar_tr PF00083.24 EON97737.1 - 4.4e-53 180.7 2.6 2.7e-51 174.9 2.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter Folate_carrier PF01770.18 EON97737.1 - 0.098 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier FAT PF02259.23 EON97738.1 - 1.4e-129 432.3 0.7 1.4e-129 432.3 0.7 1.8 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.8 EON97738.1 - 4.1e-75 251.1 1.7 2.4e-68 229.1 0.0 4.9 5 1 0 5 5 5 3 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.27 EON97738.1 - 4.2e-74 249.5 0.1 7.8e-74 248.6 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 EON97738.1 - 1.5e-44 150.4 1.5 7.3e-44 148.2 0.1 3.1 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT PF02985.22 EON97738.1 - 3.3e-17 61.1 16.5 0.0014 18.7 0.0 12.0 12 0 0 12 12 11 3 HEAT repeat HEAT_2 PF13646.6 EON97738.1 - 5.9e-17 61.8 6.3 0.0022 18.3 0.0 8.7 9 1 0 9 9 9 3 HEAT repeats FATC PF02260.20 EON97738.1 - 4.3e-13 48.8 0.1 1.7e-12 46.9 0.1 2.1 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.6 EON97738.1 - 1.3e-09 38.4 19.8 0.0037 17.7 0.1 10.5 8 4 4 12 12 10 2 HEAT-like repeat Cnd1 PF12717.7 EON97738.1 - 8.4e-07 29.2 4.8 0.021 14.9 0.0 6.2 4 2 3 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EON97738.1 - 7e-06 24.9 3.1 0.08 11.5 0.0 4.6 3 3 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.8 EON97738.1 - 0.00012 21.8 1.0 1.5 8.3 0.0 5.7 6 1 1 7 7 7 1 CLASP N terminal RICTOR_N PF14664.6 EON97738.1 - 0.011 14.7 1.7 0.46 9.4 0.0 3.5 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term VirDNA-topo-I_N PF09266.10 EON97738.1 - 0.023 14.8 0.1 0.063 13.4 0.1 1.7 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal Sec7_N PF12783.7 EON97738.1 - 0.034 14.0 3.8 2.4 8.1 0.0 5.0 5 0 0 5 5 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF383 PF04063.14 EON97738.1 - 0.089 12.4 1.0 4.4 6.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF383) DUF3730 PF12530.8 EON97738.1 - 0.094 12.3 0.2 29 4.1 0.0 4.1 3 1 2 5 5 5 0 Protein of unknown function (DUF3730) GCIP PF13324.6 EON97739.1 - 6.7e-21 75.1 0.0 2.3e-20 73.3 0.0 1.9 2 1 0 2 2 2 1 Grap2 and cyclin-D-interacting RRN3 PF05327.11 EON97739.1 - 0.0056 15.3 0.1 0.0081 14.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 EON97739.1 - 0.0095 15.8 2.4 0.01 15.8 0.6 1.9 2 0 0 2 2 2 1 Sigma-70, non-essential region Pox_Ag35 PF03286.14 EON97739.1 - 0.021 14.6 3.8 0.056 13.2 2.8 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.10 EON97739.1 - 0.22 11.9 9.8 1 9.8 9.5 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 EON97739.1 - 0.33 11.2 3.9 0.78 10.0 3.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Uso1_p115_C PF04871.13 EON97739.1 - 0.77 10.1 9.7 2 8.8 9.7 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region SnoaL_2 PF12680.7 EON97740.1 - 0.00016 22.2 0.7 0.00046 20.8 0.7 1.7 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 EON97740.1 - 0.00046 20.3 2.2 0.00086 19.4 2.2 1.5 1 0 0 1 1 1 1 SnoaL-like domain ING PF12998.7 EON97740.1 - 0.00072 20.1 0.0 0.0089 16.6 0.0 2.5 1 1 1 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding CENP-B_dimeris PF09026.10 EON97740.1 - 0.11 12.9 2.3 13 6.2 1.0 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TRAM1 PF08390.11 EON97741.1 - 1e-24 85.9 0.0 3e-24 84.4 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.16 EON97741.1 - 1.2e-22 80.6 26.1 1.2e-22 80.6 26.1 2.9 2 2 0 2 2 2 1 TLC domain DUF4408 PF14364.6 EON97741.1 - 0.0053 16.5 0.2 0.017 14.9 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4408) MA3 PF02847.17 EON97742.1 - 5.6e-23 81.1 0.1 1.8e-22 79.4 0.0 1.9 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 EON97742.1 - 6.2e-13 48.9 0.3 6.2e-13 48.9 0.3 1.9 2 0 0 2 2 2 1 MIF4G domain Glyco_hydro_16 PF00722.21 EON97744.1 - 1.8e-11 43.8 0.7 2.9e-11 43.2 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 ABC_tran PF00005.27 EON97746.1 - 4.1e-18 66.2 0.0 7.3e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EON97746.1 - 7.8e-15 55.3 0.1 1.1e-14 54.8 0.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EON97746.1 - 4.7e-06 26.2 0.1 5.9e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EON97746.1 - 0.0026 18.0 0.3 0.068 13.4 0.3 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Methyltransf_25 PF13649.6 EON97747.1 - 1.8e-07 31.8 0.0 2.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON97747.1 - 5e-07 30.3 0.0 7.9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 EON97747.1 - 0.0021 16.7 0.0 0.0029 16.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 EON97747.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EON97747.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Dus PF01207.17 EON97748.1 - 1.3e-56 192.0 0.0 9.7e-56 189.1 0.0 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) CBP4 PF07960.11 EON97748.1 - 4 7.3 7.8 5.4 6.9 5.0 2.3 2 0 0 2 2 2 0 CBP4 STb_secrete PF09075.10 EON97750.1 - 0.063 13.3 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory PalH PF08733.10 EON97751.1 - 4.9e-118 393.9 0.0 5.6e-118 393.7 0.0 1.0 1 0 0 1 1 1 1 PalH/RIM21 DUF4231 PF14015.6 EON97751.1 - 0.2 12.2 5.6 28 5.2 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) CAAD PF14159.6 EON97751.1 - 0.3 11.0 3.2 0.33 10.8 0.2 2.6 1 1 2 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DPM2 PF07297.12 EON97752.1 - 7.8e-29 99.8 2.2 9e-29 99.6 2.2 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) COX14 PF14880.6 EON97752.1 - 0.00074 19.3 0.8 0.027 14.3 0.0 2.0 2 0 0 2 2 2 1 Cytochrome oxidase c assembly PIG-P PF08510.12 EON97752.1 - 0.0017 18.2 1.3 0.0019 18.1 1.3 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 EON97752.1 - 0.0031 17.6 5.7 0.011 15.8 5.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4229) LapA_dom PF06305.11 EON97752.1 - 0.0094 15.7 0.2 0.0094 15.7 0.2 1.8 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain CBF PF03914.17 EON97753.1 - 8.6e-35 120.3 0.3 2.7e-34 118.7 0.2 1.9 1 1 0 1 1 1 1 CBF/Mak21 family Ribosomal_L6 PF00347.23 EON97754.1 - 6.5e-28 97.2 11.2 7.2e-15 55.4 3.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DHDPS PF00701.22 EON97755.1 - 2.9e-45 154.2 0.0 3.3e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Herpes_UL46 PF03387.14 EON97755.1 - 0.18 10.5 0.1 0.26 10.0 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL46 protein HAD PF12710.7 EON97756.1 - 2.1e-06 28.3 0.0 7.1e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 EON97756.1 - 0.14 11.9 0.0 2.3 8.0 0.0 2.5 2 1 0 2 2 2 0 NLI interacting factor-like phosphatase APH PF01636.23 EON97757.1 - 5.3e-44 150.9 0.0 1.3e-43 149.7 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EON97757.1 - 0.00014 21.3 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 EON97757.1 - 0.0025 17.4 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EON97757.1 - 0.0032 17.1 0.0 0.039 13.5 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.14 EON97757.1 - 0.082 12.1 0.0 0.55 9.4 0.0 2.1 1 1 0 1 1 1 0 Fructosamine kinase DUF1679 PF07914.11 EON97757.1 - 0.093 11.6 0.0 2 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Kdo PF06293.14 EON97757.1 - 0.13 11.6 0.0 0.34 10.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rax2 PF12768.7 EON97758.1 - 1.8e-76 256.4 0.3 1.1e-74 250.6 0.0 3.4 3 0 0 3 3 3 1 Cortical protein marker for cell polarity Syndecan PF01034.20 EON97758.1 - 0.16 11.9 2.1 0.35 10.8 2.1 1.5 1 0 0 1 1 1 0 Syndecan domain Reg_prop PF07494.11 EON97758.1 - 4.6 7.8 13.6 10 6.7 0.1 6.4 8 0 0 8 8 8 0 Two component regulator propeller Cullin PF00888.22 EON97759.1 - 6.3e-22 77.9 0.0 1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 EON97759.1 - 2.5e-21 75.9 0.2 7.3e-21 74.4 0.2 1.9 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 zf-C2H2 PF00096.26 EON97760.1 - 0.0021 18.4 3.7 0.25 11.9 0.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EON97760.1 - 0.016 16.0 2.0 6.4 7.9 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 EON97760.1 - 0.061 12.8 0.1 0.14 11.6 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EON97760.1 - 0.1 12.7 0.2 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain bZIP_1 PF00170.21 EON97761.1 - 6.1e-10 39.1 17.3 7.3e-09 35.6 16.0 2.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 EON97761.1 - 5.8e-06 26.7 16.5 1.6e-05 25.3 16.5 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 EON97761.1 - 0.0003 20.8 21.6 0.0069 16.5 20.2 2.9 2 1 0 2 2 2 1 Basic region leucine zipper DUF3584 PF12128.8 EON97761.1 - 0.016 12.8 11.7 0.021 12.4 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Ins134_P3_kin PF05770.11 EON97761.1 - 0.045 13.3 0.2 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain FapA PF03961.13 EON97761.1 - 0.09 11.4 12.5 0.13 10.9 12.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A KASH_CCD PF14662.6 EON97761.1 - 0.19 11.5 21.2 0.37 10.6 21.2 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DDE_Tnp_ISL3 PF01610.17 EON97761.1 - 0.43 10.3 7.5 0.81 9.4 7.5 1.4 1 0 0 1 1 1 0 Transposase UPF0242 PF06785.11 EON97761.1 - 1.4 8.9 22.7 2.4 8.2 22.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ARD PF03079.14 EON97761.1 - 1.6 8.9 9.1 3.5 7.8 9.1 1.5 1 0 0 1 1 1 0 ARD/ARD' family 5_nucleotid PF05761.14 EON97761.1 - 2.1 7.2 9.5 3.2 6.6 9.5 1.3 1 0 0 1 1 1 0 5' nucleotidase family UBA_e1_thiolCys PF10585.9 EON97761.1 - 9.8 6.0 12.2 2.1 8.2 8.5 1.7 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Tim17 PF02466.19 EON97762.1 - 1.2e-12 48.2 0.3 2e-12 47.5 0.2 1.4 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family SPC25 PF06703.11 EON97763.1 - 4e-56 189.3 0.1 5e-56 189.0 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) adh_short PF00106.25 EON97764.1 - 4.2e-30 104.7 3.0 5.8e-30 104.2 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON97764.1 - 1.9e-27 96.4 2.8 2.7e-27 95.8 2.8 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON97764.1 - 7.1e-13 48.9 0.5 9.5e-13 48.4 0.5 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EON97764.1 - 3.3e-10 39.6 0.3 4.1e-10 39.3 0.3 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EON97764.1 - 0.00023 20.7 0.3 0.00076 19.0 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EON97764.1 - 0.0012 19.1 1.0 0.041 14.1 2.4 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EON97764.1 - 0.0044 17.1 0.4 0.0095 16.0 0.4 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.8 EON97764.1 - 0.041 13.7 0.4 0.081 12.7 0.4 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pkinase PF00069.25 EON97765.1 - 1.5e-44 152.4 0.2 1.8e-35 122.6 0.1 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EON97765.1 - 6.6e-18 64.9 0.1 5.4e-17 61.9 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EON97765.1 - 2e-05 24.7 0.0 0.018 15.0 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EON97765.1 - 5e-05 22.8 0.3 0.069 12.4 0.1 3.0 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.22 EON97765.1 - 0.0034 17.0 0.5 0.055 13.1 0.0 2.1 1 1 1 2 2 2 1 RIO1 family FTA2 PF13095.6 EON97765.1 - 0.18 11.4 0.1 2.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ribul_P_3_epim PF00834.19 EON97766.1 - 3.6e-63 212.6 0.0 1.5e-62 210.5 0.0 1.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 EON97766.1 - 0.077 12.6 0.1 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family P34-Arc PF04045.14 EON97767.1 - 1.8e-104 348.7 0.2 2.7e-104 348.1 0.2 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc SNase PF00565.17 EON97767.1 - 1.2e-21 77.2 0.0 3.3e-21 75.8 0.0 1.8 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Rad51 PF08423.11 EON97768.1 - 5.1e-127 422.4 0.0 6.2e-127 422.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EON97768.1 - 2.5e-08 33.7 0.0 3.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 EON97768.1 - 3.7e-08 33.2 0.0 5.2e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 EON97768.1 - 3.2e-05 24.5 1.5 6.9e-05 23.4 0.4 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 EON97768.1 - 3.4e-05 23.3 0.1 9.7e-05 21.8 0.1 1.8 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 EON97768.1 - 0.025 13.9 0.1 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 EON97768.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 EON97768.1 - 0.099 12.7 0.2 0.59 10.2 0.1 2.2 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain PAXNEB PF05625.11 EON97768.1 - 0.19 10.8 0.3 0.84 8.7 0.0 1.9 2 0 0 2 2 2 0 PAXNEB protein GCV_T PF01571.21 EON97769.1 - 2.6e-83 279.3 0.0 3.2e-83 279.0 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EON97769.1 - 7.8e-24 83.4 0.2 1.5e-23 82.5 0.2 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF3659 PF12396.8 EON97769.1 - 0.16 11.9 0.8 0.25 11.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) TFIIF_beta_N PF17683.1 EON97770.1 - 2.2e-31 109.3 0.1 5.7e-31 108.0 0.0 1.7 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 EON97770.1 - 2.4e-27 94.9 0.1 3.9e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 EON97770.1 - 0.014 16.3 0.2 0.027 15.3 0.1 1.6 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tox-ART-HYD1 PF15633.6 EON97770.1 - 0.069 13.8 0.2 1.3 9.7 0.0 2.3 1 1 1 2 2 2 0 HYD1 signature containing ADP-ribosyltransferase Aminotran_5 PF00266.19 EON97771.1 - 7.8e-61 206.1 0.1 1.6e-60 205.0 0.1 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EON97771.1 - 1.1e-06 27.4 0.0 1.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EON97771.1 - 2.8e-05 23.5 0.1 0.00011 21.6 0.1 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Ofd1_CTDD PF10637.9 EON97772.1 - 4.3e-93 311.3 0.0 1e-88 297.0 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EON97772.1 - 2.6e-25 88.9 0.0 1.9e-24 86.1 0.0 2.4 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EON97772.1 - 1.5e-11 45.0 0.0 3.3e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkr1 PF08636.10 EON97773.1 - 4.2e-34 116.5 2.4 5.6e-34 116.1 2.4 1.1 1 0 0 1 1 1 1 ER protein Pkr1 OAD_gamma PF04277.13 EON97773.1 - 0.38 11.4 2.4 0.46 11.1 0.6 2.1 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain NAD_binding_10 PF13460.6 EON97774.1 - 9.9e-12 45.1 0.3 2.9e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EON97774.1 - 1.4e-11 44.4 0.0 1.8e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EON97774.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EON97774.1 - 0.0011 19.2 0.0 0.0027 18.0 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain V-ATPase_H_N PF03224.14 EON97775.1 - 2e-78 263.9 0.0 2.7e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EON97775.1 - 5.2e-35 120.1 0.0 2.7e-34 117.8 0.0 2.2 2 0 0 2 2 2 1 V-ATPase subunit H Med4 PF10018.9 EON97775.1 - 0.05 13.3 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Glycophorin_A PF01102.18 EON97777.1 - 0.0018 18.5 0.1 0.0037 17.5 0.1 1.5 1 0 0 1 1 1 1 Glycophorin A SKG6 PF08693.10 EON97777.1 - 0.011 15.2 2.5 0.028 13.8 2.5 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Amnionless PF14828.6 EON97777.1 - 0.068 12.0 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Amnionless Nup160 PF11715.8 EON97778.1 - 2.3e-96 323.6 0.1 3.2e-96 323.1 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 EMC3_TMCO1 PF01956.16 EON97779.1 - 1.9e-45 154.7 0.9 2.6e-45 154.2 0.9 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Ribosomal_L21p PF00829.21 EON97780.1 - 1e-14 54.6 0.0 1.3e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein MMS19_N PF14500.6 EON97781.1 - 8.7e-57 192.7 0.0 1.5e-56 191.9 0.0 1.3 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II CRM1_C PF08767.11 EON97781.1 - 0.013 14.7 0.4 0.052 12.7 0.1 2.0 2 1 0 2 2 2 0 CRM1 C terminal BORCS7 PF16088.5 EON97781.1 - 0.064 13.5 0.0 0.24 11.7 0.0 1.9 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 Questin_oxidase PF14027.6 EON97782.1 - 1.2e-97 327.5 0.4 1.5e-97 327.2 0.4 1.1 1 0 0 1 1 1 1 Questin oxidase-like AMPK1_CBM PF16561.5 EON97782.1 - 0.051 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase zf-met PF12874.7 EON97783.1 - 4.9e-06 26.7 1.3 1.3e-05 25.4 1.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EON97783.1 - 6.7e-06 26.3 4.5 1.5e-05 25.1 4.5 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EON97783.1 - 1.3e-05 25.4 3.1 0.16 12.5 1.4 2.5 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 EON97783.1 - 4.5e-05 23.3 2.4 8.2e-05 22.5 2.4 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EON97783.1 - 0.00027 21.2 2.4 0.00076 19.7 2.4 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EON97783.1 - 0.00029 21.4 3.2 0.00089 19.9 3.2 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EON97783.1 - 0.0047 17.2 0.2 0.0082 16.5 0.2 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Metallophos PF00149.28 EON97784.1 - 3.9e-11 43.8 0.7 7.9e-11 42.8 0.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AP3D1 PF06375.11 EON97784.1 - 0.042 14.1 18.8 2.8 8.1 2.0 3.3 3 0 0 3 3 3 0 AP-3 complex subunit delta-1 Ydc2-catalyt PF09159.10 EON97784.1 - 2.2 7.9 8.4 0.23 11.1 3.0 1.9 2 0 0 2 2 2 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Mt_ATP-synt_B PF05405.14 EON97785.1 - 6.4e-53 178.7 6.9 9.9e-53 178.1 6.9 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Tli4_N PF18443.1 EON97785.1 - 0.021 15.2 0.6 0.037 14.4 0.6 1.4 1 0 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain Dak2 PF02734.17 EON97785.1 - 0.24 11.3 2.7 1.3 8.9 2.7 2.1 1 1 0 1 1 1 0 DAK2 domain Ehrlichia_rpt PF09528.10 EON97785.1 - 1.8 8.1 5.8 0.26 10.8 1.1 2.0 2 0 0 2 2 2 0 Ehrlichia tandem repeat (Ehrlichia_rpt) zf-CCCH PF00642.24 EON97786.1 - 2e-06 27.6 27.3 0.0013 18.6 0.1 5.6 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EON97786.1 - 0.0048 16.7 0.0 0.0048 16.7 0.0 4.8 5 1 0 5 5 5 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EON97786.1 - 0.0095 16.0 1.1 0.0095 16.0 1.1 6.0 5 1 0 5 5 5 2 Zinc finger domain zf-CCCH_3 PF15663.5 EON97786.1 - 0.012 15.8 2.0 0.012 15.8 2.0 3.6 1 1 2 3 3 3 0 Zinc-finger containing family NUFIP1 PF10453.9 EON97787.1 - 1.3e-09 37.7 0.0 5.5e-09 35.7 0.0 2.0 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf_CCCH_4 PF18345.1 EON97787.1 - 0.027 14.5 6.8 0.04 14.0 6.8 1.3 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 EON97787.1 - 0.028 14.3 4.4 0.043 13.7 4.4 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4355 PF14265.6 EON97787.1 - 0.03 14.6 6.1 0.1 12.8 6.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) PIEZO PF15917.5 EON97787.1 - 0.12 11.9 5.8 0.22 11.0 5.8 1.3 1 0 0 1 1 1 0 Piezo CCDC-167 PF15188.6 EON97787.1 - 0.55 10.6 3.3 3.4 8.1 3.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 CSRNP_N PF16019.5 EON97787.1 - 6.4 6.6 7.7 0.47 10.3 1.6 2.1 3 0 0 3 3 3 0 Cysteine/serine-rich nuclear protein N-terminus PRKG1_interact PF15898.5 EON97787.1 - 6.7 7.7 11.6 0.79 10.7 6.6 2.0 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain SlyX PF04102.12 EON97787.1 - 7.8 7.2 8.0 1.7 9.3 3.6 2.2 2 0 0 2 2 2 0 SlyX RNA_pol_Rbc25 PF08292.12 EON97788.1 - 1e-33 116.3 0.7 3.3e-33 114.7 0.7 1.8 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EON97788.1 - 2.2e-14 53.5 0.0 3.7e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EON97788.1 - 0.0024 18.2 0.2 0.013 15.8 0.0 2.1 2 0 0 2 2 2 1 S1 RNA binding domain Xrn1_D3 PF18194.1 EON97788.1 - 0.14 12.3 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Exoribonuclease 1 Domain-3 THF_DHG_CYH PF00763.23 EON97789.1 - 1.9e-27 95.9 0.3 2.9e-27 95.2 0.3 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EON97789.1 - 2.6e-14 52.8 0.0 4.6e-09 35.8 0.0 2.5 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Peptidase_Mx1 PF15890.5 EON97790.1 - 0.0069 15.8 0.1 0.015 14.7 0.1 1.5 1 1 0 1 1 1 1 Putative zinc-binding metallo-peptidase Ribosomal_60s PF00428.19 EON97792.1 - 3.9e-26 91.5 10.4 4.5e-26 91.3 10.4 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 EON97792.1 - 0.0026 18.0 0.0 0.0044 17.3 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain UBA_6 PF18039.1 EON97792.1 - 0.035 14.0 0.4 0.064 13.2 0.1 1.6 2 0 0 2 2 2 0 UBA-like domain DUF3824 PF12868.7 EON97792.1 - 0.6 10.8 3.3 0.78 10.4 3.3 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Rad17 PF03215.15 EON97793.1 - 6.6e-24 84.8 0.0 1.3e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EON97793.1 - 0.013 15.9 0.0 0.038 14.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EON97793.1 - 0.02 14.6 0.1 0.042 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EON97793.1 - 0.024 14.6 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EON97793.1 - 0.024 15.0 0.1 0.068 13.6 0.1 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EON97793.1 - 0.19 12.1 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_6 PF12774.7 EON97793.1 - 0.25 10.3 0.0 0.42 9.5 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region DUF4349 PF14257.6 EON97794.1 - 0.1 12.0 0.8 0.2 11.1 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) GTA_holin_3TM PF11351.8 EON97794.1 - 2.4 8.7 3.9 0.97 10.0 0.2 2.1 1 1 1 2 2 2 0 Holin of 3TMs, for gene-transfer release SPT2 PF08243.11 EON97795.1 - 6.3e-10 39.6 28.3 6.3e-10 39.6 28.3 2.7 2 1 0 2 2 2 1 SPT2 chromatin protein Sigma70_ner PF04546.13 EON97796.1 - 1.1 9.1 3.8 2.1 8.2 3.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 EON97796.1 - 4.5 5.5 9.2 6.7 4.9 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein GEN1_C PF18380.1 EON97796.1 - 8.1 7.4 6.8 34 5.4 4.3 2.7 3 0 0 3 3 3 0 Holliday junction resolvase Gen1 C-terminal domain LSM PF01423.22 EON97797.1 - 1.2e-18 66.6 0.0 1.5e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EON97797.1 - 0.00012 22.1 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain CPP1-like PF11833.8 EON97798.1 - 0.15 11.7 1.1 0.2 11.3 1.1 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like WD40 PF00400.32 EON97799.1 - 2.7e-40 135.6 25.2 1.3e-05 25.9 0.3 10.7 10 1 0 10 10 10 9 WD domain, G-beta repeat Utp12 PF04003.12 EON97799.1 - 1.4e-18 67.1 0.2 4.5e-18 65.5 0.2 1.7 2 0 0 2 2 2 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EON97799.1 - 1.3e-13 51.0 8.4 0.005 17.1 0.1 7.6 6 3 3 9 9 8 4 Anaphase-promoting complex subunit 4 WD40 domain FMO-like PF00743.19 EON97799.1 - 1.9e-10 39.8 0.1 4e-10 38.7 0.1 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EON97799.1 - 1e-06 28.1 0.0 3.1e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EON97799.1 - 2.4e-06 27.1 0.0 8.3e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase WD40_like PF17005.5 EON97799.1 - 5.8e-05 22.6 0.1 1.4 8.2 0.0 3.3 3 0 0 3 3 3 3 WD40-like domain DUF5601 PF18151.1 EON97799.1 - 0.00058 20.1 0.3 0.0024 18.1 0.1 2.2 2 0 0 2 2 1 1 Domain of unknown function (DUF5601) Nup160 PF11715.8 EON97799.1 - 0.00085 18.1 2.4 0.33 9.6 0.1 4.4 4 1 1 5 5 5 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EON97799.1 - 0.0011 17.8 0.6 0.099 11.4 0.1 3.1 2 1 0 3 3 3 1 Nup133 N terminal like eIF2A PF08662.11 EON97799.1 - 0.011 15.7 0.1 0.74 9.7 0.0 3.7 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EON97799.1 - 0.012 14.5 6.0 2.6 6.9 0.0 4.8 4 1 1 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EON97799.1 - 0.044 12.1 0.0 7.2 4.8 0.0 2.3 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 EON97799.1 - 0.16 11.7 0.3 1.8 8.3 0.0 2.7 2 0 0 2 2 2 0 TUP1-like enhancer of split CAP59_mtransfer PF11735.8 EON97800.1 - 4.1e-83 278.8 0.0 5.3e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Vps26 PF03643.15 EON97801.1 - 1.6e-130 434.1 0.7 1.8e-130 433.9 0.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EON97801.1 - 0.00021 21.4 0.6 0.5 10.4 0.0 3.5 2 1 2 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EON97801.1 - 0.006 17.0 0.0 0.085 13.3 0.0 2.3 1 1 2 3 3 3 1 Arrestin (or S-antigen), C-terminal domain IL17R_D_N PF16742.5 EON97801.1 - 0.067 13.2 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Ribosomal_S8e PF01201.22 EON97802.1 - 1.3e-45 154.9 1.8 2e-45 154.4 1.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e Red1 PF07964.11 EON97802.1 - 0.14 10.4 4.4 0.16 10.2 4.4 1.0 1 0 0 1 1 1 0 Rec10 / Red1 CBF PF03914.17 EON97803.1 - 6.7e-29 101.1 3.2 7.8e-29 100.9 0.0 2.5 2 1 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.11 EON97803.1 - 3.3e-27 94.8 0.4 1.3e-26 92.9 0.1 2.3 2 0 0 2 2 2 1 Nucleolar complex-associated protein DUF2115 PF09888.9 EON97803.1 - 0.25 11.8 0.8 14 6.2 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) CAF1A PF12253.8 EON97803.1 - 3.1 8.1 14.2 0.28 11.4 1.7 3.6 3 0 0 3 3 3 0 Chromatin assembly factor 1 subunit A BP28CT PF08146.12 EON97804.1 - 8.4e-47 158.9 0.9 3.8e-46 156.8 0.9 2.3 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EON97804.1 - 4.9e-26 91.4 2.6 4.9e-26 91.4 2.6 5.3 4 1 2 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 EON97804.1 - 1.9e-06 27.6 8.8 0.041 14.1 0.0 6.0 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EON97804.1 - 0.0025 18.2 14.8 0.26 11.7 0.5 5.5 6 0 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 EON97804.1 - 0.2 12.2 19.8 4.8 7.8 0.3 6.9 7 2 0 7 7 7 0 HEAT-like repeat DUF3517 PF12030.8 EON97805.1 - 1.9e-114 382.1 1.4 1.7e-113 379.0 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3517) UCH PF00443.29 EON97805.1 - 1.1e-31 110.3 0.3 1.1e-30 107.0 0.2 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EON97805.1 - 1.5e-16 60.9 1.3 1.8e-14 54.1 0.0 2.8 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PCP PF02429.15 EON97805.1 - 0.08 13.3 0.1 0.22 11.9 0.1 1.7 1 0 0 1 1 1 0 Peridinin-chlorophyll A binding protein Pox_A3L PF05288.11 EON97805.1 - 0.19 11.8 5.2 0.097 12.7 0.3 3.0 3 0 0 3 3 3 0 Poxvirus A3L Protein DUF2508 PF10704.9 EON97805.1 - 0.47 10.6 1.9 7.8 6.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) Pyr_redox_2 PF07992.14 EON97806.1 - 2.1e-44 152.0 0.0 2.7e-39 135.2 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON97806.1 - 3.2e-14 53.3 0.0 1.5e-12 47.9 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON97806.1 - 0.00064 19.1 0.0 0.88 8.8 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON97806.1 - 0.012 15.8 0.0 7 7.0 0.0 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EON97806.1 - 0.014 15.0 0.5 1 8.9 0.0 3.2 3 1 1 4 4 4 0 FAD dependent oxidoreductase Dehydratase_hem PF13816.6 EON97808.1 - 1.7e-88 297.0 0.0 1.9e-88 296.8 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase Trep_Strep PF09605.10 EON97809.1 - 0.0066 16.4 0.1 0.0092 16.0 0.1 1.2 1 0 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF4231 PF14015.6 EON97809.1 - 0.014 15.9 0.3 0.023 15.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF4381 PF14316.6 EON97809.1 - 0.024 14.9 0.8 0.029 14.6 0.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) UL42 PF17638.2 EON97809.1 - 0.051 13.6 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 HCMV UL42 Vezatin PF12632.7 EON97809.1 - 0.093 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes UPF0370 PF13980.6 EON97809.1 - 0.15 12.1 4.2 0.24 11.5 4.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) TRI12 PF06609.13 EON97810.1 - 1e-45 156.3 23.3 1.2e-45 156.1 23.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EON97810.1 - 1.4e-15 57.1 36.4 2.2e-15 56.5 33.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily hDGE_amylase PF14701.6 EON97811.1 - 2.6e-177 590.3 0.0 3.3e-177 590.0 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EON97811.1 - 6.4e-116 387.4 0.0 1.3e-115 386.4 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EON97811.1 - 4.6e-90 301.7 0.0 1.3e-89 300.2 0.0 1.8 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EON97811.1 - 9.1e-28 96.2 0.1 2.2e-27 95.0 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Ribosomal_L5_C PF00673.21 EON97812.1 - 1.5e-21 76.4 0.0 2.1e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EON97812.1 - 2.4e-20 72.6 0.0 7.2e-20 71.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Sugar_tr PF00083.24 EON97813.1 - 2.6e-132 441.9 23.6 3e-132 441.7 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON97813.1 - 2.2e-18 66.3 38.1 2.1e-15 56.5 22.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily CPSase_L_D2 PF02786.17 EON97814.1 - 6.3e-82 274.2 0.5 1e-81 273.5 0.5 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EON97814.1 - 1.2e-68 230.8 0.0 2.3e-68 229.9 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain HMGL-like PF00682.19 EON97814.1 - 5.6e-27 95.0 0.0 9.9e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_carb_N PF00289.22 EON97814.1 - 1.7e-21 76.8 0.0 3.7e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 EON97814.1 - 7e-19 67.4 3.3 8.6e-19 67.2 1.6 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_carb_C PF02785.19 EON97814.1 - 1.6e-13 50.6 0.0 4.5e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EON97814.1 - 1.8e-11 44.0 0.0 3.5e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EON97814.1 - 2.6e-10 40.0 0.2 7.7e-07 28.9 0.1 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 EON97814.1 - 1.6e-08 34.3 0.1 3.4e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EON97814.1 - 5.2e-06 26.6 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EON97814.1 - 4.1e-05 23.3 0.1 0.00015 21.5 0.1 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 EON97814.1 - 0.00011 21.5 0.1 0.07 12.3 0.0 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 EON97814.1 - 0.00043 19.9 0.2 0.001 18.7 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EON97814.1 - 0.0008 19.2 0.0 0.0058 16.4 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 EON97814.1 - 0.0076 15.5 0.0 0.029 13.6 0.0 1.9 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 EON97814.1 - 0.0083 16.8 0.2 11 6.8 0.0 3.2 4 0 0 4 4 2 0 HlyD family secretion protein DUF2118 PF09891.9 EON97814.1 - 0.033 14.1 0.0 0.12 12.3 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) ATPgrasp_YheCD PF14398.6 EON97814.1 - 0.043 13.1 0.0 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 YheC/D like ATP-grasp NQRA PF05896.11 EON97814.1 - 0.058 12.8 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GCV_H PF01597.19 EON97814.1 - 0.084 12.8 0.4 0.42 10.5 0.1 2.3 2 0 0 2 2 2 0 Glycine cleavage H-protein QRPTase_N PF02749.16 EON97814.1 - 0.15 12.1 0.1 1.6 8.8 0.0 2.5 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain MFS_1 PF07690.16 EON97815.1 - 7.3e-41 140.3 52.3 7.3e-41 140.3 52.3 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EON97815.1 - 6.7e-18 64.4 16.6 1.1e-17 63.7 16.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EON97815.1 - 8.3e-13 48.0 12.6 8.3e-13 48.0 12.6 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter MPC PF03650.13 EON97816.1 - 4.5e-35 120.1 0.0 7.4e-35 119.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers LSM PF01423.22 EON97816.1 - 2.3e-18 65.6 0.0 3.7e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 LSM domain AIG2_2 PF13772.6 EON97817.1 - 5.5e-06 26.7 0.0 3.7e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 AIG2-like family FAD_binding_3 PF01494.19 EON97818.1 - 1e-09 38.1 0.8 0.043 13.1 0.1 3.3 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 EON97818.1 - 0.00019 21.1 0.7 0.00076 19.2 0.3 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EON97818.1 - 0.00052 20.2 0.2 0.0012 19.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EON97818.1 - 0.0022 17.3 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EON97818.1 - 0.0026 17.8 0.1 0.0057 16.7 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EON97818.1 - 0.095 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON97818.1 - 0.11 11.2 0.3 0.16 10.6 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EON97818.1 - 0.2 10.8 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EON97818.1 - 0.28 11.7 0.5 0.63 10.6 0.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 EON97819.1 - 3.6e-44 150.5 0.0 1.7e-43 148.3 0.0 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EON97819.1 - 1.4e-43 148.6 0.5 2.2e-43 148.0 0.5 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K_oxygenase PF13434.6 EON97819.1 - 0.032 13.4 0.1 0.05 12.7 0.1 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF4440 PF14534.6 EON97820.1 - 6.6e-06 26.5 0.0 9.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 EON97820.1 - 0.0022 18.6 0.0 0.003 18.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain RHD_DNA_bind PF00554.22 EON97820.1 - 0.027 14.4 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Rel homology DNA-binding domain NTF2 PF02136.20 EON97820.1 - 0.03 14.9 0.0 0.051 14.1 0.0 1.4 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain AA_permease_2 PF13520.6 EON97821.1 - 1.6e-63 215.1 18.4 1.9e-63 214.8 18.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EON97821.1 - 5.1e-10 38.6 13.3 5.6e-10 38.4 13.3 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.25 EON97822.1 - 8.6e-08 31.9 0.0 2.5e-05 23.8 0.0 2.4 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON97822.1 - 1.9e-05 24.3 0.0 3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EON97822.1 - 0.012 15.5 0.0 0.027 14.3 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 EON97822.1 - 0.018 14.5 0.0 0.066 12.7 0.0 1.8 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.19 EON97822.1 - 0.026 13.8 0.3 0.041 13.1 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain RmlD_sub_bind PF04321.17 EON97822.1 - 0.055 12.6 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 EON97822.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.18 EON97822.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ABC_tran PF00005.27 EON97823.1 - 3.6e-37 127.9 0.0 1.2e-25 90.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EON97823.1 - 1.8e-22 80.3 14.3 1.8e-22 80.3 14.3 1.4 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EON97823.1 - 1.3e-12 47.6 0.6 1.6e-05 24.4 0.0 3.1 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EON97823.1 - 0.00033 20.6 0.0 0.22 11.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 EON97823.1 - 0.00065 19.5 0.3 3.3 7.4 0.0 3.7 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_25 PF13481.6 EON97823.1 - 0.0049 16.5 0.0 0.0099 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EON97823.1 - 0.0056 16.9 0.1 0.034 14.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EON97823.1 - 0.014 14.5 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EON97823.1 - 0.014 15.1 1.9 0.018 14.8 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EON97823.1 - 0.023 14.1 0.0 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 EON97823.1 - 0.026 14.7 0.0 9.1 6.6 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATPase PF06745.13 EON97823.1 - 0.032 13.6 0.0 0.084 12.2 0.0 1.7 1 0 0 1 1 1 0 KaiC MMR_HSR1 PF01926.23 EON97823.1 - 0.032 14.3 0.0 0.092 12.8 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EON97823.1 - 0.054 13.9 0.9 0.19 12.1 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain NACHT PF05729.12 EON97823.1 - 0.058 13.3 0.3 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.17 EON97823.1 - 0.083 13.0 0.3 0.17 12.0 0.3 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain IIGP PF05049.13 EON97823.1 - 0.086 11.9 1.2 0.84 8.6 0.1 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DUF2075 PF09848.9 EON97823.1 - 0.13 11.4 0.3 0.37 10.0 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SGL PF08450.12 EON97825.1 - 1.9e-06 27.7 0.3 2.7e-06 27.2 0.1 1.4 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Glyco_transf_54 PF04666.13 EON97826.1 - 3.7e-05 22.8 0.0 0.00029 19.8 0.0 2.2 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region MatE PF01554.18 EON97827.1 - 2.4e-29 102.0 5.5 3.8e-29 101.4 5.5 1.2 1 0 0 1 1 1 1 MatE GPI-anchored PF10342.9 EON97828.1 - 2.4e-17 63.4 2.7 2.4e-17 63.4 2.7 1.5 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4512 PF14975.6 EON97828.1 - 0.0089 16.8 0.2 0.015 16.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4512) TRI12 PF06609.13 EON97829.1 - 9.1e-52 176.3 22.3 1.1e-51 175.9 22.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EON97829.1 - 2.3e-25 89.3 54.4 3.4e-24 85.4 54.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON97829.1 - 2.6e-09 36.5 6.9 2.6e-09 36.5 6.9 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter SDA1 PF05285.12 EON97830.1 - 1.6e-90 304.1 53.3 2.2e-89 300.3 42.9 3.1 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 EON97830.1 - 2.1e-23 82.4 0.0 5.8e-23 81.0 0.0 1.8 1 0 0 1 1 1 1 NUC130/3NT domain DUF2277 PF10041.9 EON97830.1 - 0.013 15.9 0.7 0.99 9.8 0.2 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) DIOX_N PF14226.6 EON97831.1 - 4e-23 82.4 0.0 5.4e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Fungal_trans PF04082.18 EON97832.1 - 2.1e-10 40.1 0.0 3.3e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_6 PF13480.7 EON97832.1 - 0.13 12.5 0.0 2.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Fringe PF02434.16 EON97833.1 - 4.1e-05 23.2 2.5 0.00043 19.8 2.5 2.2 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 EON97833.1 - 0.056 13.3 0.1 0.23 11.2 0.1 2.1 1 1 0 1 1 1 0 Galactosyltransferase Arginase PF00491.21 EON97834.1 - 2.3e-75 253.7 0.0 3e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EON97834.1 - 0.05 13.8 0.1 0.085 13.1 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain KR PF08659.10 EON97835.1 - 3.9e-41 140.9 0.2 6.8e-41 140.2 0.2 1.4 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 EON97835.1 - 9.9e-09 35.4 0.2 3e-08 33.9 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 EON97835.1 - 0.00023 20.7 0.1 0.00049 19.6 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON97835.1 - 0.0019 17.8 0.2 0.0033 17.0 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GMC_oxred_N PF00732.19 EON97836.1 - 2.1e-27 96.3 0.1 3e-27 95.8 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EON97836.1 - 1.1e-22 81.1 0.0 2.1e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EON97836.1 - 0.00028 20.1 0.0 0.00036 19.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Ribosomal_S7e PF01251.18 EON97837.1 - 1.1e-80 269.7 0.1 1.3e-80 269.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e PX PF00787.24 EON97838.1 - 1.4e-15 57.3 0.0 2.3e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 PX domain DUF745 PF05335.13 EON97838.1 - 0.011 15.5 4.5 0.054 13.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Syntaxin-6_N PF09177.11 EON97838.1 - 0.16 12.5 2.8 15 6.2 0.0 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal KxDL PF10241.9 EON97838.1 - 8.2 6.8 6.6 1.5 9.2 2.9 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein adh_short PF00106.25 EON97839.1 - 6e-35 120.5 0.0 8.1e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON97839.1 - 4.5e-17 62.4 0.0 6e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON97839.1 - 2.2e-05 24.5 0.1 0.00015 21.8 0.0 2.0 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 EON97839.1 - 0.019 15.2 0.0 0.17 12.2 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EON97839.1 - 0.028 13.5 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EON97839.1 - 0.028 14.3 0.0 0.071 13.0 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H-binding LIP PF03583.14 EON97840.1 - 9e-53 179.4 0.1 3.2e-52 177.6 0.1 1.7 1 1 0 1 1 1 1 Secretory lipase Flavin_Reduct PF01613.18 EON97842.1 - 4.8e-17 62.4 0.0 7e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain MFS_1 PF07690.16 EON97843.1 - 3.9e-30 105.0 18.8 4.7e-16 58.7 12.6 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily LapA_dom PF06305.11 EON97843.1 - 0.16 11.8 0.0 0.16 11.8 0.0 3.7 4 1 0 4 4 4 0 Lipopolysaccharide assembly protein A domain AMP-binding PF00501.28 EON97844.1 - 8.8e-69 232.1 0.0 7.4e-36 123.6 0.0 4.0 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 EON97844.1 - 1.1e-11 45.5 0.0 2.9e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 EON97844.1 - 0.0048 16.9 0.8 0.0048 16.9 0.8 1.8 2 0 0 2 2 2 1 Gas vesicle protein G RBM1CTR PF08081.11 EON97844.1 - 0.057 13.5 1.1 0.18 11.9 1.1 1.8 1 0 0 1 1 1 0 RBM1CTR (NUC064) family DEAD PF00270.29 EON97845.1 - 7.4e-47 159.4 0.1 1.5e-46 158.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON97845.1 - 6.6e-29 100.5 0.1 1.2e-27 96.4 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 EON97845.1 - 0.0068 15.2 0.7 0.033 13.0 0.0 2.3 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 RNAse_A_bac PF18431.1 EON97845.1 - 3.5 8.6 5.6 2.5 9.1 2.4 2.4 2 1 1 3 3 3 0 Bacterial CdiA-CT RNAse A domain Iso_dh PF00180.20 EON97846.1 - 1e-86 291.2 0.0 1.2e-86 291.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.16 EON97847.1 - 2.9e-10 39.6 29.1 2.9e-10 39.6 29.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EON97847.1 - 6e-08 32.6 2.9 6e-08 32.6 2.9 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 EON97847.1 - 1.1e-07 31.1 8.1 1.1e-07 31.1 8.1 2.5 3 1 0 3 3 3 1 Sugar (and other) transporter ATPase_gene1 PF09527.10 EON97847.1 - 1.5 9.0 13.3 0.76 10.0 2.4 3.3 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Methyltransf_2 PF00891.18 EON97848.1 - 4.3e-28 98.1 0.1 2.9e-27 95.4 0.0 2.1 1 1 1 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 EON97848.1 - 6.9e-10 38.8 0.1 2e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Dimerisation domain Dimerisation PF08100.11 EON97848.1 - 0.00023 21.1 0.0 0.00058 19.8 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain TFIIE_beta PF02186.15 EON97848.1 - 0.026 14.8 0.0 1.2 9.5 0.0 2.6 2 0 0 2 2 2 0 TFIIE beta subunit core domain tRNA-synt_2 PF00152.20 EON97849.1 - 5.6e-71 239.2 0.0 8.7e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 EON97849.1 - 1.5e-15 57.0 0.1 2.2e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 EON97849.1 - 1.7e-06 27.9 0.0 3.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Phage_H_T_join PF05521.11 EON97849.1 - 0.045 14.3 0.1 0.17 12.4 0.1 1.9 2 0 0 2 2 2 0 Phage head-tail joining protein DDRGK PF09756.9 EON97849.1 - 4.7 6.8 12.8 9.6 5.7 12.8 1.4 1 0 0 1 1 1 0 DDRGK domain PDEase_II PF02112.15 EON97850.1 - 1.4e-06 27.7 0.0 1.7e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II EBP PF05241.12 EON97851.1 - 0.46 9.9 9.5 1.1 8.7 9.5 1.9 1 1 0 1 1 1 0 Emopamil binding protein EB1 PF03271.17 EON97852.1 - 2.2e-17 63.0 2.1 4.6e-17 62.0 2.1 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EON97852.1 - 6.4e-08 32.8 0.3 1.1e-07 32.0 0.3 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 EON97852.1 - 0.089 12.9 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 CH-like domain in sperm protein Annexin PF00191.20 EON97853.1 - 8.9e-50 166.6 4.9 1.4e-13 50.7 0.1 4.3 4 0 0 4 4 4 4 Annexin UPF0254 PF06787.11 EON97853.1 - 0.015 15.1 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) TPR_8 PF13181.6 EON97853.1 - 0.017 15.3 0.1 0.1 12.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2255 PF10012.9 EON97853.1 - 0.11 12.6 1.3 0.43 10.8 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2255) DUF2019 PF09450.10 EON97853.1 - 0.12 12.3 4.7 0.35 10.8 0.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF2019) Sugar_tr PF00083.24 EON97854.1 - 7.7e-68 229.4 15.8 1.1e-49 169.6 2.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EON97854.1 - 2.3e-16 59.7 16.1 2.7e-10 39.7 4.8 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Fig1 PF12351.8 EON97854.1 - 0.25 11.2 6.2 0.066 13.1 0.8 2.3 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Phage_holin_7_1 PF16081.5 EON97854.1 - 1.4 9.1 4.6 0.99 9.6 2.3 1.9 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Sulfotransfer_4 PF17784.1 EON97855.1 - 1.3e-18 67.6 0.0 1.3e-18 67.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EON97855.1 - 0.065 13.6 0.0 0.074 13.4 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase family ATP-grasp_3 PF02655.14 EON97856.1 - 0.008 16.2 0.0 0.047 13.7 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 EON97856.1 - 0.11 12.1 0.1 0.63 9.6 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain p450 PF00067.22 EON97858.1 - 7e-10 38.2 0.0 9.3e-10 37.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.14 EON97859.1 - 3.7e-22 78.9 0.1 8.1e-22 77.8 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON97859.1 - 7.1e-06 25.5 0.6 0.0078 15.5 0.1 3.0 2 2 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EON97859.1 - 8.9e-06 25.8 1.2 0.13 12.3 0.3 2.6 1 1 1 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EON97859.1 - 1.8e-05 24.0 2.1 0.0023 17.1 0.1 3.0 1 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.14 EON97859.1 - 4.9e-05 22.2 0.0 0.017 13.9 0.0 2.7 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.6 EON97859.1 - 0.00017 21.8 1.1 0.00039 20.6 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EON97859.1 - 0.00024 20.8 0.7 0.0007 19.3 0.5 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EON97859.1 - 0.003 16.9 0.9 0.0074 15.6 0.5 1.9 1 1 1 2 2 2 1 FAD binding domain GIDA PF01134.22 EON97859.1 - 0.0076 15.4 1.5 0.23 10.5 0.4 2.9 2 1 1 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EON97859.1 - 0.01 14.9 0.1 0.028 13.5 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 EON97859.1 - 0.03 13.5 0.2 0.075 12.3 0.1 1.6 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.6 EON97859.1 - 0.13 11.3 0.0 6.8 5.7 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF4448 PF14610.6 EON97860.1 - 0.045 13.5 0.5 4 7.2 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) 7tm_3 PF00003.22 EON97860.1 - 0.048 13.4 5.0 0.2 11.4 0.1 1.9 1 1 1 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF2678 PF10856.8 EON97860.1 - 0.085 12.8 1.0 0.31 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) DUF4131 PF13567.6 EON97860.1 - 0.087 12.5 0.1 0.13 11.9 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) TMEM132D_C PF15706.5 EON97860.1 - 0.17 11.6 1.3 0.23 11.3 0.0 1.8 2 1 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Ribosomal_L36 PF00444.18 EON97861.1 - 0.12 12.6 2.4 5.9 7.2 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein L36 p450 PF00067.22 EON97862.1 - 1.3e-39 136.2 0.0 1.5e-39 136.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mannosidase_ig PF17786.1 EON97863.1 - 4.8e-15 55.9 0.5 2.2e-14 53.8 0.3 2.1 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 EON97863.1 - 6.8e-13 48.2 0.0 1.3e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Ig-fold domain AUDH_Cupin PF18637.1 EON97864.1 - 5.5e-63 211.7 1.1 7.4e-63 211.3 1.1 1.2 1 0 0 1 1 1 1 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain PBP3 PF18056.1 EON97864.1 - 6e-33 113.3 0.0 8.6e-33 112.8 0.0 1.2 1 0 0 1 1 1 1 Penicillin Binding Protein 3 Domain Condensation PF00668.20 EON97865.1 - 0.00059 18.6 0.0 0.00066 18.5 0.0 1.1 1 0 0 1 1 1 1 Condensation domain PUB_1 PF18486.1 EON97865.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain 2OG-FeII_Oxy PF03171.20 EON97866.1 - 2.6e-16 59.9 0.0 4.5e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EON97866.1 - 3.1e-16 60.2 0.0 4.4e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF2070 PF09843.9 EON97867.1 - 0.016 13.6 2.6 0.022 13.1 2.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) adh_short PF00106.25 EON97868.1 - 5.5e-13 48.8 0.1 8.3e-13 48.2 0.1 1.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON97868.1 - 3.4e-09 36.6 0.0 4.7e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON97868.1 - 0.017 15.0 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 KR domain AA_permease PF00324.21 EON97870.1 - 2.4e-67 227.6 36.2 1.5e-44 152.4 15.8 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 EON97870.1 - 2.3e-13 49.8 12.7 2.3e-13 49.8 12.7 2.1 1 1 1 2 2 2 1 Amino acid permease DUF2101 PF09874.9 EON97870.1 - 0.14 11.8 2.8 0.22 11.2 1.8 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2101) MFS_1 PF07690.16 EON97871.1 - 2.1e-29 102.5 58.7 8.4e-23 80.8 37.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Vma12 PF11712.8 EON97871.1 - 4.6 7.3 10.1 18 5.4 5.7 2.4 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PAP2_3 PF14378.6 EON97873.1 - 3.8e-38 131.1 8.1 5e-28 98.1 1.7 2.3 2 0 0 2 2 2 2 PAP2 superfamily PAP2 PF01569.21 EON97873.1 - 0.00079 19.2 5.7 0.00081 19.2 2.5 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 EON97873.1 - 0.052 14.1 3.9 0.071 13.7 1.1 2.5 2 1 0 2 2 2 0 PAP2 superfamily C-terminal Alpha-amylase PF00128.24 EON97874.1 - 1e-19 71.3 0.0 5.3e-19 69.0 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 EON97874.1 - 7.8e-10 39.1 0.2 2.5e-09 37.5 0.1 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Yeast-kill-tox PF09207.11 EON97874.1 - 2.9 8.6 6.6 0.74 10.5 1.0 2.8 2 1 0 2 2 2 0 Yeast killer toxin Aldo_ket_red PF00248.21 EON97875.1 - 1e-43 149.6 0.0 1.3e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Imm61 PF15598.6 EON97875.1 - 0.021 14.7 0.0 0.079 12.9 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 61 Glyco_hydro_31 PF01055.26 EON97876.1 - 2.4e-100 336.8 3.1 5.2e-100 335.7 3.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EON97876.1 - 1e-07 32.2 1.1 3.4e-07 30.5 1.1 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 EON97876.1 - 1.7e-05 25.0 0.4 0.0016 18.7 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF5110) Dynactin_p62 PF05502.13 EON97877.1 - 1.4e-218 726.5 0.0 1.7e-218 726.2 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family Spot_14 PF07084.12 EON97877.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 DUF1996 PF09362.10 EON97878.1 - 1.1e-16 61.6 1.1 1.6e-16 61.1 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AphA_like PF14557.6 EON97879.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator Amino_oxidase PF01593.24 EON97880.1 - 9.8e-06 25.1 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase LpoB PF13036.6 EON97880.1 - 0.18 11.8 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB G6PD_C PF02781.16 EON97881.1 - 1.3e-114 382.3 0.0 1.8e-114 381.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EON97881.1 - 8.1e-61 205.7 0.0 1.4e-60 204.9 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.8 EON97881.1 - 0.015 15.0 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) Cyclin_N PF00134.23 EON97882.1 - 6.9e-45 151.9 0.0 2.3e-44 150.2 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EON97882.1 - 3.5e-34 117.4 0.0 6.5e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain HEPN_Toprim_N PF18871.1 EON97882.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 DEAD PF00270.29 EON97883.1 - 4.5e-21 75.4 0.0 1.8e-20 73.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON97883.1 - 1.2e-20 73.9 0.4 1.2e-15 57.8 0.0 3.9 3 1 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EON97883.1 - 1.6e-18 67.2 5.5 5e-18 65.6 5.5 1.9 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 EON97883.1 - 4.9e-12 45.6 0.1 9.5e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 RQC domain ResIII PF04851.15 EON97883.1 - 1.3e-05 25.3 0.0 4.7e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HRDC PF00570.23 EON97883.1 - 2.3e-05 24.3 0.0 5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 HRDC domain SNF2_N PF00176.23 EON97883.1 - 0.016 13.9 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain PAP2 PF01569.21 EON97884.1 - 2.7e-23 82.2 9.1 1.6e-22 79.8 6.8 2.7 2 1 0 2 2 2 1 PAP2 superfamily SseC PF04888.12 EON97884.1 - 0.2 11.2 0.4 0.33 10.5 0.4 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Mad3_BUB1_I PF08311.12 EON97885.1 - 2.4e-43 147.1 0.5 4.9e-43 146.0 0.5 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 EON97885.1 - 1.1e-08 34.8 0.0 5.7e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Mad3_BUB1_II PF08171.11 EON97885.1 - 5.5e-08 32.8 0.0 5.3e-07 29.7 0.0 2.5 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.17 EON97885.1 - 0.00072 18.9 0.0 0.0033 16.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.16 EON97886.1 - 2.8e-24 85.7 46.6 5.5e-23 81.5 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily tRNA-synt_1 PF00133.22 EON97887.1 - 3.5e-220 732.3 0.7 3.8e-219 728.9 0.7 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EON97887.1 - 6e-30 104.2 0.1 1.6e-29 102.8 0.1 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EON97887.1 - 3.4e-17 62.3 0.1 2.7e-06 26.4 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EON97887.1 - 3.2e-12 46.4 7.5 1.8e-10 40.6 0.0 2.9 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 EON97887.1 - 0.00093 19.4 2.8 0.00093 19.4 2.8 2.8 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 EON97887.1 - 0.021 14.2 0.0 0.53 9.6 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain PepSY PF03413.19 EON97887.1 - 0.17 12.5 1.9 0.43 11.2 0.0 2.7 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Thioredoxin PF00085.20 EON97889.1 - 1.6e-63 211.1 4.6 1e-31 108.9 0.3 3.7 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 EON97889.1 - 9.6e-51 172.3 2.2 6.2e-37 127.3 0.8 3.5 2 2 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EON97889.1 - 1.5e-10 41.2 0.0 0.033 14.5 0.0 4.5 3 1 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 EON97889.1 - 4.9e-10 39.2 0.9 0.0011 18.4 0.0 3.0 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EON97889.1 - 6e-09 36.0 0.2 0.0011 19.1 0.0 3.7 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EON97889.1 - 7.4e-09 36.0 1.7 0.00051 20.5 0.1 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain Calsequestrin PF01216.17 EON97889.1 - 7.8e-08 31.7 0.8 7.8e-08 31.7 0.8 1.9 2 1 0 2 2 2 1 Calsequestrin AhpC-TSA PF00578.21 EON97889.1 - 9.1e-08 32.1 1.4 0.011 15.6 0.1 3.5 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 EON97889.1 - 1e-07 31.7 2.9 0.0062 16.3 0.0 3.5 3 0 0 3 3 3 3 Redoxin ERp29_N PF07912.13 EON97889.1 - 7.9e-05 22.8 0.8 1.2 9.3 0.0 4.0 3 1 0 3 3 3 1 ERp29, N-terminal domain DSBA PF01323.20 EON97889.1 - 0.026 14.3 0.2 10 5.8 0.0 3.7 3 1 0 3 3 3 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 EON97889.1 - 0.027 14.5 1.3 0.093 12.8 0.1 2.5 3 0 0 3 3 3 0 Thioredoxin domain Thioredoxin_4 PF13462.6 EON97889.1 - 0.046 13.9 6.3 1.1 9.4 0.2 4.0 4 2 0 4 4 4 0 Thioredoxin SHD1 PF03983.12 EON97890.1 - 1.7e-35 120.6 0.0 3e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 EON97890.1 - 2.2e-35 120.0 9.6 5.1e-13 48.4 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 EON97890.1 - 4.3e-34 116.1 10.1 1.2e-11 44.3 0.3 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 EON97890.1 - 6.9e-24 83.3 0.1 8.8e-08 31.7 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.11 EON97890.1 - 5.9e-06 26.5 4.3 0.048 13.9 0.6 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain SAM_4 PF18017.1 EON97890.1 - 0.00039 20.3 0.0 0.00094 19.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 EON97890.1 - 0.0012 18.9 0.0 0.22 11.6 0.0 3.1 3 0 0 3 3 3 1 SH3 domain DUF4192 PF13830.6 EON97890.1 - 0.0022 18.1 0.6 0.0022 18.1 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4192) Rpp20 PF12328.8 EON97890.1 - 0.068 13.1 1.1 0.15 12.0 1.0 1.6 1 1 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P UQ_con PF00179.26 EON97891.1 - 2.3e-25 88.9 0.0 2.7e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EON97891.1 - 6.7e-06 25.8 0.0 8.7e-06 25.5 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EON97891.1 - 0.0049 16.7 0.1 0.0064 16.4 0.1 1.2 1 0 0 1 1 1 1 UEV domain Prok-E2_A PF14457.6 EON97891.1 - 0.069 12.8 0.0 0.089 12.4 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family A RWD PF05773.22 EON97891.1 - 0.11 12.7 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain F-box-like PF12937.7 EON97893.1 - 0.0003 20.6 0.2 0.00062 19.6 0.2 1.5 1 0 0 1 1 1 1 F-box-like Ribosomal_L2_C PF03947.18 EON97894.1 - 3.4e-47 159.8 1.6 5.2e-47 159.2 0.7 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EON97894.1 - 3.7e-26 90.9 0.6 7.2e-26 90.0 0.6 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain HTH_17 PF12728.7 EON97894.1 - 0.04 14.1 0.1 0.093 12.9 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain ATP-synt PF00231.19 EON97895.1 - 3.2e-80 269.8 5.3 3.9e-80 269.6 5.3 1.0 1 0 0 1 1 1 1 ATP synthase COesterase PF00135.28 EON97896.1 - 2.7e-45 155.2 0.0 3.3e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EON97896.1 - 4.4e-06 26.7 0.2 0.00024 21.0 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EON97896.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family ERAP1_C PF11838.8 EON97897.1 - 1.4e-87 294.2 0.0 1.2e-86 291.1 0.0 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EON97897.1 - 2.1e-84 282.4 0.9 3.6e-84 281.7 0.9 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EON97897.1 - 5e-54 183.3 0.3 8.2e-54 182.6 0.3 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Methyltransf_2 PF00891.18 EON97897.1 - 0.045 13.0 0.0 6.2 6.1 0.0 3.4 4 0 0 4 4 4 0 O-methyltransferase domain FAA_hydrolase PF01557.18 EON97898.1 - 9.1e-50 169.3 0.0 1.1e-49 169.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Prefoldin_2 PF01920.20 EON97899.1 - 9.5e-22 77.0 0.5 1.2e-21 76.7 0.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Fib_alpha PF08702.10 EON97899.1 - 0.26 11.5 3.6 0.33 11.1 0.1 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Uso1_p115_C PF04871.13 EON97899.1 - 0.65 10.4 5.2 5.9 7.3 5.2 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1932 PF09130.11 EON97900.1 - 4.4e-22 77.8 0.2 9.9e-22 76.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 EON97900.1 - 1.7e-08 34.8 0.0 3.2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EON97900.1 - 9.4e-08 32.5 0.2 2.8e-07 31.0 0.2 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EON97900.1 - 0.00097 18.5 0.1 0.0017 17.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EON97900.1 - 0.0074 16.2 0.3 0.019 14.9 0.1 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SSTK-IP PF15836.5 EON97900.1 - 0.0091 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 SSTK-interacting protein, TSSK6-activating co-chaperone protein PDH PF02153.17 EON97900.1 - 0.027 13.5 0.1 0.038 13.0 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase 3-HAO PF06052.12 EON97901.1 - 2.7e-66 221.9 0.0 3.1e-66 221.7 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EON97901.1 - 1.5e-06 27.8 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Cupin domain DZR PF12773.7 EON97901.1 - 0.00091 19.2 2.7 0.0015 18.5 2.7 1.4 1 0 0 1 1 1 1 Double zinc ribbon Cupin_1 PF00190.22 EON97901.1 - 0.0011 18.5 0.1 0.0017 18.0 0.1 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 EON97901.1 - 0.0019 18.1 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain C1_1 PF00130.22 EON97901.1 - 0.065 13.1 2.4 0.79 9.7 0.6 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 EON97901.1 - 0.18 11.9 2.0 0.42 10.8 0.3 2.1 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 EON97901.1 - 1.9 9.3 5.8 3.8 8.3 0.5 2.2 1 1 1 2 2 2 0 zinc-ribbon family BAH PF01426.18 EON97902.1 - 4.5e-05 23.3 0.1 0.0001 22.2 0.1 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 EON97902.1 - 0.003 17.4 2.7 0.0077 16.1 2.7 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EON97902.1 - 0.01 16.1 0.6 0.025 14.8 0.1 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-RING-like PF08746.11 EON97902.1 - 0.049 14.0 0.9 0.11 12.9 0.9 1.5 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 EON97902.1 - 0.15 12.3 1.6 0.34 11.1 1.6 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Topoisom_I_N PF02919.15 EON97903.1 - 3.9e-95 317.4 3.8 3.9e-95 317.4 3.8 2.7 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 EON97903.1 - 6.9e-95 316.7 7.0 6.9e-95 316.7 7.0 1.8 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 EON97903.1 - 5.9e-30 103.0 0.4 2.1e-29 101.2 0.4 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain Csm1_N PF18504.1 EON97903.1 - 5.1 7.5 10.2 3.1 8.2 5.1 3.1 2 0 0 2 2 2 0 Csm1 N-terminal domain BLOC1_2 PF10046.9 EON97903.1 - 9.4 6.6 10.0 11 6.5 1.0 3.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 adh_short_C2 PF13561.6 EON97904.1 - 3.4e-38 131.5 1.1 4.5e-38 131.1 1.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON97904.1 - 3.4e-37 127.8 0.1 4.3e-37 127.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON97904.1 - 7.5e-12 45.5 1.1 1e-11 45.1 1.1 1.1 1 0 0 1 1 1 1 KR domain RhaA PF06134.11 EON97904.1 - 0.017 14.3 0.0 0.043 12.9 0.0 1.6 2 0 0 2 2 2 0 L-rhamnose isomerase (RhaA) 3HCDH_N PF02737.18 EON97904.1 - 0.14 12.0 1.2 0.28 11.1 0.2 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SNARE_assoc PF09335.11 EON97905.1 - 1.5e-17 64.2 10.8 4.5e-17 62.6 4.6 2.9 3 0 0 3 3 3 1 SNARE associated Golgi protein MRI PF15325.6 EON97905.1 - 0.091 13.9 3.6 0.19 12.8 1.2 2.1 2 0 0 2 2 2 0 Modulator of retrovirus infection Chordopox_L2 PF05803.12 EON97905.1 - 0.1 12.4 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Chordopoxvirus L2 protein E1-E2_ATPase PF00122.20 EON97905.1 - 9.9 5.6 6.2 96 2.4 6.2 2.2 1 1 0 1 1 1 0 E1-E2 ATPase A_deaminase PF00962.22 EON97906.1 - 1.3e-123 412.5 0.2 1.9e-123 412.0 0.2 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.11 EON97906.1 - 1.3e-73 247.9 9.3 1.1e-48 166.0 3.3 2.2 1 1 1 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.15 EON97906.1 - 0.029 13.5 0.2 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Nucleotide-sugar transporter EamA PF00892.20 EON97906.1 - 5.3 7.2 20.7 7.3 6.8 10.3 3.1 2 1 0 2 2 2 0 EamA-like transporter family Mito_carr PF00153.27 EON97907.1 - 2.6e-46 155.5 1.8 1.2e-16 60.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Hydrolase_4 PF12146.8 EON97908.1 - 2.8e-13 49.7 0.2 1.7e-12 47.2 0.1 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON97908.1 - 4e-11 44.0 7.9 6.3e-11 43.3 7.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON97908.1 - 1.1e-10 41.6 0.0 2e-10 40.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EON97908.1 - 0.024 14.3 0.1 0.037 13.7 0.1 1.2 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 EON97908.1 - 0.31 11.1 0.8 1.2 9.2 0.9 1.8 2 0 0 2 2 2 0 Thioesterase domain Pkinase PF00069.25 EON97909.1 - 1.7e-69 234.2 0.0 2.4e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON97909.1 - 6.2e-34 117.4 0.1 1.2e-33 116.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EON97909.1 - 7.2e-06 25.5 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EON97909.1 - 0.0027 17.1 0.0 0.0064 15.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EON97909.1 - 0.0095 15.5 0.0 0.078 12.5 0.0 2.4 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Aminotran_1_2 PF00155.21 EON97910.1 - 3.6e-18 65.9 0.0 4.5e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EON97910.1 - 1.8e-05 23.8 0.0 4.4e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 EON97910.1 - 0.052 12.8 0.0 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF202 PF02656.15 EON97911.1 - 0.00017 21.9 3.4 0.00017 21.9 3.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Yos1 PF08571.10 EON97912.1 - 2.3e-24 85.4 0.0 2.8e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Yos1-like Sec1 PF00995.23 EON97913.1 - 1.2e-129 434.2 0.0 1.4e-129 434.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SIS PF01380.22 EON97913.1 - 0.071 13.0 0.0 6.1 6.7 0.0 2.6 3 0 0 3 3 3 0 SIS domain RsfS PF02410.15 EON97913.1 - 0.15 12.5 0.1 0.59 10.6 0.0 2.0 2 0 0 2 2 2 0 Ribosomal silencing factor during starvation PP2C PF00481.21 EON97914.1 - 6.7e-57 193.0 0.0 1.1e-56 192.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 EON97914.1 - 5.9e-38 128.4 51.0 3.4e-11 42.7 0.1 9.1 3 3 5 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 EON97914.1 - 1.9e-28 98.1 58.8 0.00013 22.2 0.4 10.6 5 2 5 11 11 11 10 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 EON97914.1 - 5.5e-27 94.6 0.0 6e-26 91.2 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.33 EON97914.1 - 5.9e-11 41.3 34.7 2.1 9.2 0.1 13.8 12 2 0 12 12 12 4 Leucine Rich Repeat LRR_9 PF14580.6 EON97914.1 - 0.00079 19.0 19.0 0.19 11.2 0.8 4.5 1 1 4 5 5 5 5 Leucine-rich repeat RA PF00788.23 EON97914.1 - 0.0009 19.8 0.0 0.0031 18.1 0.1 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_5 PF13306.6 EON97914.1 - 0.51 10.3 2.1 18 5.3 0.0 3.7 2 1 2 5 5 5 0 BspA type Leucine rich repeat region (6 copies) EXS PF03124.14 EON97916.1 - 2e-111 372.5 14.8 2.3e-111 372.3 14.8 1.0 1 0 0 1 1 1 1 EXS family ADC PF06314.11 EON97917.1 - 9.3e-15 54.8 0.0 1.6e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) FAD_binding_3 PF01494.19 EON97917.1 - 3.7e-14 52.8 0.0 5.6e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EON97917.1 - 0.0047 16.3 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase AP_endonuc_2 PF01261.24 EON97918.1 - 4.6e-35 121.0 0.1 6.5e-35 120.5 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel GPI-anchored PF10342.9 EON97919.1 - 2.7e-22 79.3 0.2 2.7e-22 79.3 0.2 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 EON97919.1 - 4.6e-05 23.3 0.0 6.7e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) CorA PF01544.18 EON97921.1 - 4.3e-14 52.5 3.4 1.2e-13 51.1 2.9 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein p450 PF00067.22 EON97922.1 - 1.8e-55 188.6 0.0 5.5e-46 157.3 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Herpes_DNAp_acc PF04929.12 EON97923.1 - 0.02 13.9 4.3 1.9 7.4 1.5 2.3 2 0 0 2 2 2 0 Herpes DNA replication accessory factor DUF1771 PF08590.10 EON97924.1 - 1.2e-15 57.6 10.5 3.1e-15 56.3 10.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EON97924.1 - 1.1e-07 32.1 0.0 4.5e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Smr domain HBS1_N PF08938.10 EON97924.1 - 0.0044 17.3 0.0 0.018 15.3 0.0 2.0 2 0 0 2 2 2 1 HBS1 N-terminus TRAM_LAG1_CLN8 PF03798.16 EON97925.1 - 6.2e-49 166.4 16.2 6.2e-49 166.4 16.2 1.5 2 0 0 2 2 2 1 TLC domain DUF2388 PF09498.10 EON97925.1 - 0.12 12.3 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) Glyco_hydro_10 PF00331.20 EON97926.1 - 1.8e-105 352.6 0.2 2e-105 352.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Taxilin PF09728.9 EON97927.1 - 0.087 12.0 1.6 0.12 11.6 1.6 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein bZIP_1 PF00170.21 EON97927.1 - 0.15 12.2 7.6 0.77 9.9 7.6 2.0 1 1 0 1 1 1 0 bZIP transcription factor zf-HIT PF04438.16 EON97928.1 - 5.9e-10 38.8 4.7 8.6e-10 38.3 4.7 1.3 1 0 0 1 1 1 1 HIT zinc finger DHC_N1 PF08385.12 EON97928.1 - 0.079 11.6 1.5 0.098 11.3 1.5 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Epimerase PF01370.21 EON97929.1 - 4.5e-18 65.6 0.0 5.8e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EON97929.1 - 3.1e-08 33.1 0.0 4.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EON97929.1 - 0.00024 20.6 0.0 0.00034 20.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EON97929.1 - 0.00053 19.1 0.0 0.002 17.2 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EON97929.1 - 0.006 16.8 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EON97929.1 - 0.15 12.3 0.0 0.42 10.9 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain NUDIX PF00293.28 EON97930.1 - 1.4e-10 41.4 0.2 1.2e-09 38.3 0.0 2.3 2 1 0 2 2 2 1 NUDIX domain Imm5 PF14423.6 EON97930.1 - 0.16 12.2 1.4 0.23 11.7 0.2 1.8 2 0 0 2 2 2 0 Immunity protein Imm5 Med14 PF08638.11 EON97931.1 - 1.1e-66 224.0 0.1 2.5e-66 222.8 0.1 1.7 1 0 0 1 1 1 1 Mediator complex subunit MED14 Glyco_hydro_20 PF00728.22 EON97932.1 - 1.8e-84 284.1 0.0 2.2e-84 283.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EON97932.1 - 3.7e-23 82.7 0.0 8.7e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EON97932.1 - 0.0021 18.8 0.0 0.0039 18.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 UCH PF00443.29 EON97934.1 - 4.1e-53 180.5 0.0 7.1e-53 179.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EON97934.1 - 5.1e-26 92.0 0.5 5.6e-19 68.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EON97934.1 - 3.1 7.2 13.1 0.32 10.4 1.8 2.9 3 1 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase WSC PF01822.19 EON97935.1 - 2.8e-87 287.0 92.7 6.4e-19 67.9 14.7 5.8 6 0 0 6 6 6 5 WSC domain Glyoxal_oxid_N PF07250.11 EON97935.1 - 6.2e-28 97.6 0.0 1.5e-27 96.4 0.0 1.6 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EON97935.1 - 3.1e-20 72.3 0.0 1.2e-19 70.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Macro_2 PF14519.6 EON97935.1 - 0.043 13.1 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 Macro-like domain Kelch_6 PF13964.6 EON97935.1 - 0.65 10.4 6.9 1.6 9.1 0.0 4.5 4 0 0 4 4 4 0 Kelch motif DUF937 PF06078.11 EON97936.1 - 0.0019 18.8 19.2 0.0028 18.3 19.2 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF937) DUF5316 PF17247.2 EON97936.1 - 5.8 7.0 7.2 0.52 10.3 2.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5316) Creatininase PF02633.14 EON97937.1 - 0.89 9.0 4.9 1.5 8.2 4.8 1.5 1 1 0 1 1 1 0 Creatinine amidohydrolase RRM_1 PF00076.22 EON97938.1 - 1.7e-17 63.0 0.0 2.6e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EON97938.1 - 1.7e-06 28.5 14.7 1.7e-06 28.5 14.7 4.1 2 2 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Methyltransf_15 PF09445.10 EON97939.1 - 6.9e-47 159.1 0.0 9.7e-47 158.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 EON97939.1 - 0.00053 19.7 0.0 0.00089 18.9 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 EON97939.1 - 0.00087 19.1 0.0 0.00094 19.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein tRNA_U5-meth_tr PF05958.11 EON97939.1 - 0.002 17.2 0.0 0.0024 16.9 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase UPF0020 PF01170.18 EON97939.1 - 0.004 16.8 0.0 0.0074 16.0 0.0 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.14 EON97939.1 - 0.053 13.1 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain CK_II_beta PF01214.18 EON97940.1 - 2.7e-76 255.5 0.1 4.6e-76 254.7 0.1 1.4 1 0 0 1 1 1 1 Casein kinase II regulatory subunit GST_N_3 PF13417.6 EON97940.1 - 9e-21 74.1 0.0 1.8e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EON97940.1 - 1.2e-16 60.8 0.0 2.7e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EON97940.1 - 2e-09 37.7 0.0 8.2e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EON97940.1 - 0.00025 21.0 1.6 0.00038 20.4 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EON97940.1 - 0.015 15.5 0.3 0.06 13.6 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin DUF5053 PF16476.5 EON97940.1 - 0.11 12.2 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) GST_C_5 PF16865.5 EON97940.1 - 0.14 12.8 0.0 0.34 11.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Acetyltransf_7 PF13508.7 EON97941.1 - 2.3e-06 27.9 0.0 3.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON97941.1 - 1.9e-05 24.9 0.0 2.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EON97941.1 - 2.1e-05 24.5 0.0 3.7e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EON97941.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein MFS_1 PF07690.16 EON97942.1 - 1.3e-31 109.9 25.8 1.3e-31 109.9 25.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON97942.1 - 5.7e-14 51.8 14.9 5.7e-14 51.8 14.9 3.1 3 1 0 3 3 3 1 Sugar (and other) transporter DUF5314 PF17241.2 EON97942.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5314) KAR9 PF08580.10 EON97943.1 - 2.2e-162 542.1 0.0 2.7e-162 541.8 0.0 1.0 1 0 0 1 1 1 1 Yeast cortical protein KAR9 PLU-1 PF08429.11 EON97943.1 - 0.015 14.5 2.1 0.52 9.4 0.0 3.0 2 1 0 3 3 3 0 PLU-1-like protein Fib_alpha PF08702.10 EON97943.1 - 0.043 14.0 0.7 8.6 6.5 0.0 3.5 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family DNA_photolyase PF00875.18 EON97943.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 DNA photolyase DEC-1_N PF04625.13 EON97943.1 - 0.17 10.8 6.8 0.32 9.9 6.8 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Prefoldin_2 PF01920.20 EON97943.1 - 4 7.4 8.9 10 6.2 0.3 3.9 4 0 0 4 4 4 0 Prefoldin subunit WD40 PF00400.32 EON97944.1 - 3.5e-46 154.2 14.1 2.2e-09 37.7 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON97944.1 - 9.2e-06 25.9 0.3 1.9 8.9 0.0 4.5 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EON97944.1 - 0.0032 16.2 2.3 3.8 6.0 0.0 3.8 1 1 3 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EON97944.1 - 0.073 12.4 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 WD40-like domain tRNA-synt_His PF13393.6 EON97946.1 - 1.4e-37 129.7 0.0 5.8e-31 107.9 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EON97946.1 - 3.5e-12 46.3 0.0 7.6e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.20 EON97946.1 - 0.0019 17.4 0.0 3.3 6.7 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.7 EON97946.1 - 0.0082 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs Mito_carr PF00153.27 EON97947.1 - 4.2e-47 158.0 7.3 1e-17 63.9 0.4 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 EON97948.1 - 5.3e-13 49.2 3.4 0.12 13.3 0.3 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF2020 PF09449.10 EON97948.1 - 0.053 13.4 0.2 2 8.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2020) adh_short PF00106.25 EON97949.1 - 1.8e-10 40.6 0.0 1e-09 38.2 0.0 2.1 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.10 EON97949.1 - 4.5e-07 29.9 0.0 7.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EON97949.1 - 8.9e-06 25.4 0.0 1.3e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Amino_oxidase PF01593.24 EON97951.1 - 3.2e-67 227.8 0.0 4.4e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HMG_box PF00505.19 EON97951.1 - 6.1e-07 29.8 10.0 3.5e-06 27.3 5.1 2.8 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EON97951.1 - 4.6e-06 27.1 3.7 4.6e-06 27.1 3.7 1.7 2 0 0 2 2 2 1 HMG-box domain PGA2 PF07543.12 EON97951.1 - 0.51 10.3 5.3 0.92 9.5 5.3 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 MFS_1 PF07690.16 EON97952.1 - 1.7e-15 56.8 13.6 2.2e-15 56.5 13.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON97952.1 - 2.6e-05 23.3 2.6 5.6e-05 22.2 2.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.18 EON97953.1 - 1.7e-07 30.6 0.0 3.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EON97953.1 - 1.7e-07 31.3 10.8 3.1e-07 30.4 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 EON97953.1 - 0.017 15.5 0.1 0.05 14.1 0.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type CH PF00307.31 EON97954.1 - 0.011 15.9 0.0 0.066 13.4 0.0 2.0 2 0 0 2 2 2 0 Calponin homology (CH) domain DUF1275 PF06912.11 EON97955.1 - 1.2e-28 100.4 13.5 1.4e-28 100.2 13.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4257 PF14074.6 EON97955.1 - 0.045 13.9 0.9 0.23 11.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) FA_desaturase PF00487.24 EON97955.1 - 1.8 8.4 6.9 0.84 9.4 3.7 1.9 1 1 1 2 2 2 0 Fatty acid desaturase DUF4131 PF13567.6 EON97955.1 - 2.7 7.6 12.7 6.8 6.3 3.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) RTA1 PF04479.13 EON97956.1 - 1.5e-26 93.3 7.1 1.8e-26 93.1 7.1 1.1 1 0 0 1 1 1 1 RTA1 like protein Pex2_Pex12 PF04757.14 EON97957.1 - 1.1e-45 155.9 3.4 1.4e-45 155.7 3.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 EON97957.1 - 6.7e-11 42.3 9.5 1e-10 41.7 9.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EON97957.1 - 8.1e-11 41.6 8.1 1.3e-10 41.0 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EON97957.1 - 2e-10 40.4 5.8 2.9e-10 39.8 5.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EON97957.1 - 2.6e-09 36.8 6.5 4e-09 36.2 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EON97957.1 - 1.3e-07 31.4 5.5 2.2e-07 30.7 5.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EON97957.1 - 4.3e-07 29.8 7.3 8.5e-07 28.9 7.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EON97957.1 - 1.2e-06 28.3 6.5 1.8e-06 27.7 6.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EON97957.1 - 2.3e-06 27.8 7.2 4.4e-06 26.9 7.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EON97957.1 - 4.6e-06 26.7 7.9 7.3e-06 26.0 7.9 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EON97957.1 - 0.00027 20.7 2.5 0.00056 19.7 2.5 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 EON97957.1 - 0.00056 20.0 5.1 0.00091 19.3 5.1 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-Nse PF11789.8 EON97957.1 - 0.0049 16.7 0.8 0.0083 15.9 0.8 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Sterol_MT_C PF08498.10 EON97957.1 - 0.06 13.7 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Sterol methyltransferase C-terminal zf-RING_4 PF14570.6 EON97957.1 - 0.084 12.7 6.2 0.17 11.7 6.2 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EON97957.1 - 0.3 11.1 3.5 0.51 10.4 3.0 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EON97957.1 - 0.87 9.3 5.8 1.8 8.3 5.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF4110 PF13422.6 EON97958.1 - 2.4e-31 107.7 0.3 2.4e-31 107.7 0.3 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.6 EON97958.1 - 6.3e-23 80.5 13.5 6.4e-08 32.7 0.0 5.7 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EON97958.1 - 3.8e-18 65.0 1.7 5.2e-07 29.5 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 EON97958.1 - 1.2e-17 63.6 23.1 2.5e-06 27.4 0.0 6.6 7 2 1 8 8 8 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EON97958.1 - 2.9e-15 55.9 1.7 0.00022 21.4 0.1 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EON97958.1 - 1.9e-13 49.8 1.4 0.019 14.9 0.0 5.9 5 1 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EON97958.1 - 1.7e-10 40.3 1.4 0.0012 18.4 0.0 4.8 4 1 0 4 4 4 3 Kelch motif PI3K_1B_p101 PF10486.9 EON97958.1 - 0.23 9.2 7.6 0.41 8.4 7.6 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit zf-CCCH_2 PF14608.6 EON97959.1 - 6.9e-12 45.4 55.6 8.1e-06 26.1 10.6 5.5 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 EON97959.1 - 0.0078 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Cupin_8 PF13621.6 EON97960.1 - 7.5e-18 65.2 0.2 2.9e-16 59.9 0.2 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EON97960.1 - 3.8e-10 40.2 0.1 1.3e-09 38.5 0.1 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase TFIIF_alpha PF05793.12 EON97960.1 - 0.13 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cupin_4 PF08007.12 EON97960.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Glyco_transf_22 PF03901.17 EON97961.1 - 4.6e-42 144.7 23.7 6.4e-42 144.2 23.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family R3H PF01424.22 EON97962.1 - 9e-18 64.0 0.2 1.5e-17 63.3 0.2 1.4 1 0 0 1 1 1 1 R3H domain DEAD PF00270.29 EON97963.1 - 7.7e-46 156.1 1.6 1.2e-45 155.4 1.6 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON97963.1 - 2.7e-32 111.4 0.4 8.8e-31 106.5 0.0 2.9 2 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON97963.1 - 2.6e-06 27.5 0.0 4.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EON97963.1 - 0.00019 21.2 0.2 0.00039 20.2 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EON97963.1 - 0.00059 20.2 2.1 0.0022 18.3 0.8 2.2 2 1 0 2 2 2 1 AAA domain IL17R_D_N PF16742.5 EON97963.1 - 0.014 15.5 0.0 0.037 14.1 0.0 1.7 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D AAA_22 PF13401.6 EON97963.1 - 0.014 15.7 0.5 0.063 13.6 0.5 2.1 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 EON97963.1 - 0.045 13.3 0.2 0.067 12.7 0.2 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.14 EON97963.1 - 0.05 13.6 0.1 0.22 11.5 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 EON97963.1 - 0.051 13.4 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Helicase CMS1 PF14617.6 EON97963.1 - 0.068 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit fragilysinNterm PF16376.5 EON97963.1 - 0.094 12.5 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin DAD PF02109.16 EON97964.1 - 1.8e-44 150.5 1.9 2.1e-44 150.3 1.9 1.1 1 0 0 1 1 1 1 DAD family F_actin_cap_B PF01115.17 EON97965.1 - 2.7e-103 344.7 0.0 3.1e-103 344.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit DUF1295 PF06966.12 EON97967.1 - 3e-12 46.6 1.9 8e-12 45.2 1.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 EON97967.1 - 2.6e-05 23.2 2.9 0.00011 21.1 2.9 1.9 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 EON97967.1 - 0.1 13.0 0.2 0.51 10.8 0.1 2.1 1 1 1 2 2 2 0 Phospholipid methyltransferase Peptidase_S9 PF00326.21 EON97968.1 - 1.2e-51 175.3 0.0 2.5e-51 174.2 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family PD40 PF07676.12 EON97968.1 - 4.6e-05 23.2 0.0 0.00018 21.3 0.0 2.1 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat PWI PF01480.17 EON97969.1 - 7.5e-31 106.3 0.1 1.2e-30 105.6 0.1 1.3 1 0 0 1 1 1 1 PWI domain DUF1282 PF06930.12 EON97970.1 - 0.0018 18.1 0.4 0.0019 18.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) SVM_signal PF12113.8 EON97970.1 - 0.0031 17.4 2.0 0.005 16.7 2.0 1.3 1 0 0 1 1 1 1 SVM protein signal sequence AA_permease_2 PF13520.6 EON97970.1 - 0.0097 14.8 0.2 0.012 14.5 0.2 1.0 1 0 0 1 1 1 1 Amino acid permease Yip1 PF04893.17 EON97970.1 - 0.017 14.8 1.4 0.02 14.6 1.4 1.1 1 0 0 1 1 1 0 Yip1 domain DUF4064 PF13273.6 EON97970.1 - 0.27 11.5 5.1 2.2 8.6 1.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Glyco_hydro_16 PF00722.21 EON97971.1 - 8.5e-43 145.9 1.2 8.5e-43 145.9 1.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF3602 PF12223.8 EON97972.1 - 5e-24 84.7 12.5 3.5e-23 82.0 5.7 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) AbrB_C PF18277.1 EON97972.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 AbrB C-terminal domain TMF_TATA_bd PF12325.8 EON97973.1 - 1.5e-40 138.0 8.7 1.5e-40 138.0 8.7 5.3 2 1 2 5 5 5 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EON97973.1 - 7.2e-08 32.3 5.5 7.2e-08 32.3 5.5 8.6 2 2 7 9 9 9 2 TATA element modulatory factor 1 DNA binding GAS PF13851.6 EON97973.1 - 0.0054 16.1 75.5 0.018 14.4 19.8 4.7 3 2 1 4 4 4 4 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 EON97973.1 - 0.0076 16.3 26.4 0.0076 16.3 26.4 5.7 2 2 2 5 5 5 2 TPR/MLP1/MLP2-like protein HIP1_clath_bdg PF16515.5 EON97973.1 - 0.0095 16.5 9.0 0.0095 16.5 9.0 6.7 1 1 6 7 7 7 1 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 EON97973.1 - 0.012 15.9 14.5 0.012 15.9 14.5 4.6 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) BRE1 PF08647.11 EON97973.1 - 0.025 14.6 1.2 0.025 14.6 1.2 7.1 3 1 3 7 7 7 0 BRE1 E3 ubiquitin ligase Filament PF00038.21 EON97973.1 - 0.039 13.5 66.7 0.082 12.5 47.7 3.2 2 1 1 3 3 3 0 Intermediate filament protein KxDL PF10241.9 EON97973.1 - 1 9.7 44.5 2 8.7 5.5 7.1 2 1 5 7 7 7 0 Uncharacterized conserved protein Baculo_PEP_C PF04513.12 EON97973.1 - 1.7 8.6 22.9 1.4 9.0 0.6 4.4 2 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus FOLN PF09289.10 EON97974.1 - 0.048 13.9 0.5 0.12 12.6 0.5 1.7 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain Mon1 PF03164.14 EON97975.1 - 2.8e-153 510.8 0.0 3.2e-153 510.6 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 MMgT PF10270.9 EON97976.1 - 4.8e-36 123.1 0.0 5.6e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter WLM PF08325.10 EON97977.1 - 2.5e-28 99.5 2.1 3.4e-28 99.0 0.5 2.0 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.17 EON97977.1 - 2.6e-08 34.2 2.2 3.1e-08 33.9 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function DUF45 Spt5_N PF11942.8 EON97977.1 - 0.14 13.1 7.6 0.065 14.2 2.8 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Hydrolase_4 PF12146.8 EON97978.1 - 8.2e-19 67.8 0.0 1.7e-13 50.4 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EON97978.1 - 2.4e-12 47.0 0.1 2.8e-08 33.8 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 EON97978.1 - 2.7e-06 26.3 0.1 0.12 11.0 0.0 3.0 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 EON97978.1 - 4.5e-05 23.2 0.0 0.00021 21.0 0.0 2.0 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DUF818 PF05677.12 EON97978.1 - 9.3e-05 21.5 0.0 0.00013 21.1 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 EON97978.1 - 0.00014 21.5 0.0 0.0022 17.6 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EON97978.1 - 0.00021 22.0 0.0 0.00048 20.8 0.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EON97978.1 - 0.0004 19.9 0.0 0.0056 16.2 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EON97978.1 - 0.0015 18.4 0.0 0.48 10.2 0.0 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase BAAT_C PF08840.11 EON97978.1 - 0.0022 17.9 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 EON97978.1 - 0.061 12.9 0.0 5 6.6 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 EON97978.1 - 0.087 12.7 0.0 0.15 11.9 0.0 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EON97978.1 - 0.18 11.6 0.0 0.64 9.8 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.20 EON97978.1 - 0.2 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Cupin_2 PF07883.11 EON97979.1 - 2e-08 33.8 0.0 3.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Cupin domain SNF2_N PF00176.23 EON97980.1 - 3.5e-52 177.3 0.0 5.5e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EON97980.1 - 1.4e-16 60.8 0.1 1e-15 58.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON97980.1 - 7.2e-09 35.9 0.0 2.1e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EON97980.1 - 1.8e-05 24.1 0.0 3.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 EON97980.1 - 0.0002 21.2 0.0 0.00048 19.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 EON97980.1 - 0.071 12.7 0.5 0.51 9.9 0.2 2.2 2 0 0 2 2 2 0 DEAD_2 MCPVI PF02993.14 EON97980.1 - 3.3 7.5 8.3 0.31 10.8 1.3 2.6 2 0 0 2 2 2 0 Minor capsid protein VI DUF2406 PF10295.9 EON97981.1 - 1e-27 96.6 0.2 1e-27 96.6 0.2 2.7 3 0 0 3 3 3 1 Uncharacterised protein (DUF2406) TFIIA PF03153.13 EON97981.1 - 8.1 6.3 24.8 0.074 13.0 11.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L35Ae PF01247.18 EON97982.1 - 1.6e-41 140.4 0.3 1.8e-41 140.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EON97982.1 - 0.0002 21.5 0.0 0.25 11.6 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.9 EON97982.1 - 0.11 12.2 1.0 0.69 9.7 0.1 2.2 2 0 0 2 2 2 0 Putative transposon-encoded protein (DUF2080) Enolase_C PF00113.22 EON97983.1 - 6.6e-153 508.2 0.1 8.6e-153 507.8 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EON97983.1 - 1.3e-57 193.6 0.3 2.6e-57 192.6 0.1 1.6 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EON97983.1 - 3.3e-06 26.8 0.0 6.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EON97983.1 - 0.016 14.4 0.3 0.71 9.0 0.1 2.6 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus TauD PF02668.16 EON97984.1 - 2.9e-19 69.9 0.1 3.5e-19 69.6 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1257 PF06868.11 EON97984.1 - 0.027 14.7 0.1 0.58 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1257) Hydrolase_4 PF12146.8 EON97985.1 - 1.4e-05 24.5 0.0 4.3e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EON97985.1 - 0.00012 21.9 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EON97985.1 - 0.002 17.6 0.0 0.034 13.6 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family NuA4 PF09340.10 EON97987.1 - 3.4e-26 90.9 0.1 6.5e-26 90.0 0.1 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DUF4726 PF15855.5 EON97987.1 - 0.43 10.8 0.0 0.43 10.8 0.0 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4726) Ank_2 PF12796.7 EON97988.1 - 2.4e-53 178.6 0.1 3.7e-14 53.1 0.0 10.3 8 2 1 10 10 10 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EON97988.1 - 8.7e-37 125.0 0.0 1.1e-05 25.9 0.0 12.5 10 4 4 14 14 14 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EON97988.1 - 2e-35 116.8 4.1 0.0017 18.7 0.0 13.3 15 0 0 15 15 15 6 Ankyrin repeat Ank_5 PF13857.6 EON97988.1 - 1.3e-34 117.8 0.4 0.0014 18.9 0.0 10.9 10 1 1 11 11 11 7 Ankyrin repeats (many copies) Ank PF00023.30 EON97988.1 - 2.5e-24 84.6 14.8 0.0031 17.9 0.0 11.6 14 0 0 14 14 14 6 Ankyrin repeat DUF4980 PF16352.5 EON97988.1 - 0.14 12.2 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4980) Ion_trans PF00520.31 EON97989.1 - 2.8e-92 308.4 83.3 9.7e-32 110.1 19.3 4.1 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 EON97989.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated JSRP PF15312.6 EON97989.1 - 0.13 12.1 0.0 0.41 10.6 0.0 1.8 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein VMA21 PF09446.10 EON97990.1 - 1.4e-14 53.9 11.9 2e-14 53.4 11.9 1.3 1 0 0 1 1 1 1 VMA21-like domain adh_short_C2 PF13561.6 EON97991.1 - 1.4e-27 96.8 0.0 1.3e-26 93.6 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON97991.1 - 7.1e-17 61.5 0.0 1.4e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase dCMP_cyt_deam_1 PF00383.23 EON97991.1 - 4.5e-14 52.2 1.0 7e-14 51.5 0.2 1.7 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EON97991.1 - 3.9e-07 30.3 2.0 5.6e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EON97991.1 - 0.062 12.9 0.6 2.3 7.8 0.0 2.2 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases RNA_polI_A34 PF08208.11 EON97993.1 - 8.5e-27 94.6 14.3 8.5e-27 94.6 14.3 6.1 2 2 1 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 SR-25 PF10500.9 EON97994.1 - 6.1 6.4 12.2 8.1 6.0 12.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Drc1-Sld2 PF11719.8 EON97995.1 - 1.8e-102 344.2 26.8 2.1e-102 344.0 26.8 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein CRAL_TRIO PF00650.20 EON97996.1 - 1.2e-37 129.1 0.0 2.1e-37 128.3 0.0 1.4 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EON97996.1 - 4.2e-07 30.0 0.3 1.3e-06 28.4 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EON97996.1 - 0.0048 17.0 0.0 0.0087 16.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 EON97996.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Sugar_tr PF00083.24 EON97997.1 - 3.3e-42 144.9 20.9 7.4e-42 143.7 20.9 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON97997.1 - 4.8e-16 58.6 24.0 4.8e-16 58.6 24.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily AAA PF00004.29 EON97998.1 - 2e-45 154.4 0.2 7.7e-45 152.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EON97998.1 - 1.2e-10 41.1 0.1 7.6e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EON97998.1 - 2.3e-08 34.1 0.7 6.6e-08 32.6 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EON97998.1 - 5.3e-08 33.2 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EON97998.1 - 2.9e-07 31.0 0.6 3.7e-05 24.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 EON97998.1 - 3.2e-06 26.5 0.0 6.9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EON97998.1 - 3.3e-05 24.2 0.9 0.0088 16.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EON97998.1 - 0.00024 20.9 0.0 0.00073 19.3 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EON97998.1 - 0.00049 20.7 0.0 0.0013 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EON97998.1 - 0.00062 20.0 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EON97998.1 - 0.00084 18.9 0.1 0.0032 17.0 0.1 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EON97998.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_lid_3 PF17862.1 EON97998.1 - 0.0013 18.5 0.0 0.0031 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain TsaE PF02367.17 EON97998.1 - 0.0014 18.6 0.0 0.019 15.0 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EON97998.1 - 0.0017 18.4 0.2 0.0078 16.3 0.0 2.1 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 EON97998.1 - 0.0022 18.3 0.0 0.0046 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 EON97998.1 - 0.003 17.5 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_3 PF07726.11 EON97998.1 - 0.0056 16.5 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EON97998.1 - 0.006 16.5 0.5 0.11 12.4 0.0 2.7 2 1 1 3 3 3 1 NACHT domain AAA_30 PF13604.6 EON97998.1 - 0.0062 16.3 1.5 0.013 15.2 0.1 2.2 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EON97998.1 - 0.0072 15.7 0.2 0.016 14.6 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EON97998.1 - 0.0083 16.3 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EON97998.1 - 0.0094 15.7 0.0 0.03 14.0 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Viral_Hsp90 PF03225.14 EON97998.1 - 0.013 14.1 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue TniB PF05621.11 EON97998.1 - 0.013 14.9 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 EON97998.1 - 0.02 14.6 0.2 0.055 13.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 EON97998.1 - 0.028 13.8 0.8 0.56 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.6 EON97998.1 - 0.036 13.9 0.1 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 EON97998.1 - 0.04 13.8 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase_2 PF01637.18 EON97998.1 - 0.048 13.6 1.2 0.34 10.8 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AFG1_ATPase PF03969.16 EON97998.1 - 0.049 12.5 0.1 0.13 11.1 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase Sigma54_activat PF00158.26 EON97998.1 - 0.067 12.9 0.2 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 EON97998.1 - 0.072 12.7 1.2 0.19 11.2 0.3 2.1 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EON97998.1 - 0.083 12.2 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 EON97998.1 - 0.13 12.6 0.1 0.37 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EON97998.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EON97998.1 - 0.15 12.6 1.2 7 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain SPACA9 PF15120.6 EON97998.1 - 0.16 11.8 1.0 14 5.4 0.0 2.2 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 AAA_29 PF13555.6 EON97998.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 EON97998.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Bromodomain PF00439.25 EON97999.1 - 6.1e-19 67.9 1.8 7.8e-19 67.5 0.2 2.0 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 EON97999.1 - 4.1e-10 39.5 0.0 1.1e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Bromodomain associated PBP1_TM PF14812.6 EON97999.1 - 2.5 8.5 14.9 0.084 13.2 1.0 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.16 EON98000.1 - 6.7e-14 51.6 21.3 4.2e-13 49.0 21.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily RCC1 PF00415.18 EON98001.1 - 1.2e-29 102.6 2.5 2.4e-07 31.2 0.0 7.1 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EON98001.1 - 3e-12 46.0 25.7 6e-10 38.7 0.0 7.0 8 0 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat Mito_carr PF00153.27 EON98002.1 - 8e-58 192.4 2.3 2.4e-21 75.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec34 PF04136.15 EON98003.1 - 9.8e-37 126.1 0.1 2.4e-36 124.8 0.1 1.7 1 0 0 1 1 1 1 Sec34-like family SKA2 PF16740.5 EON98003.1 - 0.11 12.2 3.7 2.2 8.1 0.1 2.9 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Exonuc_VII_L PF02601.15 EON98003.1 - 0.44 10.1 5.3 0.38 10.3 1.0 2.5 3 0 0 3 3 3 0 Exonuclease VII, large subunit TFIID_20kDa PF03847.13 EON98004.1 - 3.3e-18 66.0 0.0 5.3e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 EON98004.1 - 0.029 14.7 0.0 0.097 13.0 0.0 1.9 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RRM_1 PF00076.22 EON98005.1 - 2.4e-12 46.5 0.0 3.9e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EON98005.1 - 2e-06 27.4 0.0 3.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EON98005.1 - 0.017 15.0 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 EON98005.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif DSBA PF01323.20 EON98006.1 - 2.4e-38 131.9 0.0 2.7e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 EON98006.1 - 0.0013 18.4 0.0 0.087 12.5 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_4 PF13462.6 EON98006.1 - 0.0044 17.2 0.0 0.0081 16.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EON98006.1 - 0.0052 17.2 0.0 1 9.8 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EON98006.1 - 0.011 15.8 0.1 0.44 10.6 0.0 2.5 3 0 0 3 3 3 0 Thioredoxin domain HypD PF01924.16 EON98006.1 - 0.15 11.1 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family Mis14 PF08641.12 EON98007.1 - 4.4e-20 72.3 0.4 1.3e-19 70.8 0.1 1.9 2 0 0 2 2 2 1 Kinetochore protein Mis14 like PAP2_3 PF14378.6 EON98008.1 - 8.1e-23 81.1 11.8 8.1e-23 81.1 11.8 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EON98008.1 - 3.8e-08 33.2 8.4 3.8e-08 33.2 8.4 3.0 1 1 1 3 3 3 1 PAP2 superfamily Y_phosphatase PF00102.27 EON98010.1 - 3.9e-47 160.8 0.1 2.2e-45 155.1 0.1 2.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EON98010.1 - 0.0031 17.6 0.4 0.029 14.5 0.0 2.7 3 1 1 4 4 4 1 Inositol hexakisphosphate DSPc PF00782.20 EON98010.1 - 0.012 15.4 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EON98010.1 - 0.042 13.8 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Prefoldin PF02996.17 EON98011.1 - 3.9e-35 120.4 0.0 6.2e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 EON98011.1 - 0.00084 19.3 0.0 0.061 13.3 0.0 2.5 2 0 0 2 2 2 1 Prefoldin subunit End3 PF12761.7 EON98011.1 - 0.021 15.0 0.3 0.4 10.8 0.0 2.3 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 KxDL PF10241.9 EON98011.1 - 0.042 14.1 0.2 5.5 7.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein SlyX PF04102.12 EON98011.1 - 0.18 12.5 1.8 2.6 8.7 0.0 2.8 3 1 0 3 3 3 0 SlyX Pkinase PF00069.25 EON98012.1 - 4.2e-71 239.4 0.0 5.1e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON98012.1 - 1.6e-28 99.7 0.0 2e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EON98012.1 - 5.5e-07 29.2 0.0 7.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EON98012.1 - 0.00011 21.1 0.0 0.00018 20.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EON98012.1 - 0.00061 19.8 0.1 0.00097 19.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EON98012.1 - 0.00069 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Lgl_C PF08596.10 EON98013.1 - 2.8e-55 187.6 0.0 8.1e-44 149.9 0.0 2.3 1 1 1 2 2 2 2 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 EON98013.1 - 2e-07 31.6 0.4 0.0082 17.0 0.1 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON98013.1 - 0.00016 21.9 0.0 0.22 11.9 0.0 3.7 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EON98013.1 - 0.021 14.2 0.0 0.051 12.9 0.0 1.6 1 0 0 1 1 1 0 WD40-like domain Glyco_hydro_47 PF01532.20 EON98016.1 - 2.8e-178 593.5 0.0 3.7e-178 593.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_43 PF04616.14 EON98017.1 - 9.6e-19 67.8 3.9 9.6e-19 67.8 3.9 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Phage_Orf51 PF06194.11 EON98017.1 - 0.034 14.2 0.1 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 Phage Conserved Open Reading Frame 51 FRQ PF09421.10 EON98018.1 - 2.6e-48 164.8 6.3 3e-48 164.6 6.3 1.0 1 0 0 1 1 1 1 Frequency clock protein IL31 PF15209.6 EON98018.1 - 0.14 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Interleukin 31 SOG2 PF10428.9 EON98018.1 - 0.92 8.6 9.3 1 8.5 9.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Amidohydro_1 PF01979.20 EON98019.1 - 2.3e-23 83.0 0.1 7.4e-14 51.8 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EON98019.1 - 2.2e-13 50.5 1.2 2.5e-08 33.9 0.4 2.4 2 1 0 2 2 2 2 Amidohydrolase family Retro_M PF02813.14 EON98019.1 - 0.12 12.8 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 Retroviral M domain Ribonuc_L-PSP PF01042.21 EON98020.1 - 1.9e-29 102.1 0.0 3.2e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP LETM1 PF07766.13 EON98020.1 - 1.4e-08 34.5 0.0 6.8e-08 32.2 0.0 1.9 1 1 0 2 2 2 1 LETM1-like protein EssA PF10661.9 EON98020.1 - 0.13 12.1 0.4 0.64 9.8 0.1 1.9 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA RINT1_TIP1 PF04437.13 EON98022.1 - 1.8e-187 624.2 0.6 2.7e-187 623.6 0.0 1.6 2 0 0 2 2 2 1 RINT-1 / TIP-1 family CRISPR_Cse2 PF09485.10 EON98022.1 - 0.0068 16.9 2.6 0.0068 16.9 2.6 2.2 2 0 0 2 2 2 1 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF4164 PF13747.6 EON98022.1 - 0.27 11.5 9.4 0.32 11.3 4.3 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Glyco_hydro_3_C PF01915.22 EON98023.1 - 1.8e-53 181.5 0.1 3.5e-53 180.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EON98023.1 - 2.4e-35 122.4 0.0 3.6e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EON98023.1 - 2.1e-12 47.0 0.2 5.1e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain Fig1 PF12351.8 EON98024.1 - 5.2e-59 199.3 3.7 5.2e-59 199.3 3.7 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 EON98024.1 - 6.9e-09 35.6 7.9 9.5e-09 35.2 7.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 EON98024.1 - 9.9e-05 21.5 6.4 0.00011 21.4 6.4 1.3 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF898) B12-binding PF02310.19 EON98024.1 - 0.031 14.3 0.0 0.48 10.5 0.0 2.4 3 0 0 3 3 3 0 B12 binding domain DUF2207 PF09972.9 EON98024.1 - 4.2 6.0 15.0 0.67 8.6 0.2 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) VanZ PF04892.12 EON98025.1 - 1.5e-06 28.9 4.3 2.8e-06 28.0 4.3 1.4 1 1 0 1 1 1 1 VanZ like family Antimicrobial20 PF08256.11 EON98025.1 - 0.1 13.1 0.1 0.23 12.1 0.1 1.6 1 0 0 1 1 1 0 Aurein-like antibiotic peptide RseC_MucC PF04246.12 EON98025.1 - 0.46 10.5 1.8 4.3 7.3 1.1 2.2 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Ferric_reduct PF01794.19 EON98026.1 - 6.2e-19 68.3 11.7 1.6e-18 67.0 11.7 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EON98026.1 - 5.4e-16 59.1 0.0 7.7e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EON98026.1 - 1.2e-05 25.9 0.0 0.23 12.1 0.0 2.4 1 1 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 EON98026.1 - 0.00013 22.0 0.0 0.00052 20.1 0.0 2.0 1 1 0 1 1 1 1 FAD-binding domain COX15-CtaA PF02628.15 EON98026.1 - 0.025 13.7 6.6 0.057 12.5 6.6 1.5 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein VWA_CoxE PF05762.14 EON98026.1 - 0.073 12.4 0.9 0.16 11.3 0.9 1.5 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein DASH_Spc34 PF08657.10 EON98027.1 - 2.5e-52 178.2 0.0 3e-26 92.8 0.0 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 UPF0242 PF06785.11 EON98027.1 - 0.081 13.0 0.6 0.11 12.5 0.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Acyl-CoA_dh_2 PF08028.11 EON98028.1 - 4.5e-06 27.0 0.5 6e-06 26.6 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON98028.1 - 1.1e-05 25.5 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Rpn3_C PF08375.11 EON98029.1 - 6.9e-26 90.5 1.7 1.9e-25 89.1 1.7 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EON98029.1 - 5.8e-21 75.0 0.4 5.1e-20 71.9 0.0 2.6 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 EON98029.1 - 0.0077 16.3 0.1 0.025 14.7 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EON98029.1 - 0.37 11.0 2.6 1.5 9.1 1.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Cas1_AcylT PF07779.12 EON98030.1 - 9.4e-84 282.0 6.8 1.2e-83 281.6 6.8 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 EON98030.1 - 6e-05 22.9 0.0 9.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p MFS_1 PF07690.16 EON98031.1 - 1.6e-37 129.2 45.3 1.6e-37 129.2 45.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3817 PF12823.7 EON98031.1 - 5.8 7.8 12.1 0.15 12.9 1.9 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) MFS_1 PF07690.16 EON98032.1 - 9.9e-33 113.5 16.9 9.9e-33 113.5 16.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON98032.1 - 1e-05 24.6 6.9 1e-05 24.6 6.9 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EON98032.1 - 0.00095 17.6 1.2 0.0014 17.0 1.2 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EON98032.1 - 0.21 10.4 10.7 0.7 8.7 3.9 2.4 2 0 0 2 2 2 0 MFS_1 like family DUF3267 PF11667.8 EON98032.1 - 0.3 11.4 3.8 2.7 8.3 0.2 3.2 3 0 0 3 3 3 0 Putative zincin peptidase DUF456 PF04306.13 EON98032.1 - 5.5 7.3 18.0 0.18 12.1 4.4 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF456) UPF0172 PF03665.13 EON98033.1 - 0.019 15.0 0.1 0.025 14.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) AAA_2 PF07724.14 EON98033.1 - 0.082 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) CLTH PF10607.9 EON98034.1 - 1.1e-35 122.7 0.0 1.9e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EON98034.1 - 1.5e-05 24.7 0.1 3.8e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 LisH zf-Di19 PF05605.12 EON98034.1 - 0.17 12.2 2.2 0.3 11.4 0.8 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Phe_ZIP PF08916.11 EON98034.1 - 0.23 12.2 0.5 0.56 11.0 0.5 1.7 1 0 0 1 1 1 0 Phenylalanine zipper Aminotran_3 PF00202.21 EON98035.1 - 5.1e-120 400.8 0.0 5.8e-120 400.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EON98035.1 - 0.0032 16.8 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EON98035.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II TPR_1 PF00515.28 EON98036.1 - 9.1e-34 113.9 12.8 7.3e-07 28.8 0.3 6.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 EON98036.1 - 1.1e-29 100.1 13.0 5.3e-06 26.1 0.0 6.7 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EON98036.1 - 6.3e-22 77.0 13.1 7e-08 32.0 3.3 7.8 2 1 6 8 8 8 4 TPR repeat TPR_8 PF13181.6 EON98036.1 - 3.4e-21 73.6 13.5 5.6e-06 26.2 0.0 7.1 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 EON98036.1 - 1.2e-17 63.9 10.5 0.0014 18.9 0.1 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 EON98036.1 - 5.6e-16 57.9 11.2 0.0029 18.3 0.0 6.6 1 1 6 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 EON98036.1 - 1.5e-15 56.3 9.8 0.01 16.2 0.9 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EON98036.1 - 3e-14 53.3 18.0 1.5e-06 28.7 5.3 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EON98036.1 - 1.4e-13 51.2 15.6 3.7e-07 30.7 1.2 4.4 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EON98036.1 - 2.1e-13 49.3 11.5 0.012 15.6 0.0 5.5 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 EON98036.1 - 7.7e-12 45.0 10.7 0.021 15.4 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EON98036.1 - 2e-09 37.5 2.7 0.023 14.8 1.1 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EON98036.1 - 5e-07 29.9 16.2 0.00017 21.7 6.2 3.5 1 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 EON98036.1 - 4.7e-06 27.1 0.6 12 6.7 0.0 4.6 4 0 0 4 4 4 0 Sel1 repeat MIT PF04212.18 EON98036.1 - 0.00026 21.0 11.4 6.6 6.9 0.1 5.2 4 1 1 5 5 5 1 MIT (microtubule interacting and transport) domain TPR_15 PF13429.6 EON98036.1 - 0.00091 18.5 12.4 0.031 13.5 0.8 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EON98036.1 - 0.0026 17.2 9.8 0.2 11.0 0.4 3.2 1 1 2 3 3 3 2 MalT-like TPR region PknG_TPR PF16918.5 EON98036.1 - 0.017 13.9 0.2 0.017 13.9 0.2 2.0 1 1 1 2 2 2 0 Protein kinase G tetratricopeptide repeat SRP68 PF16969.5 EON98036.1 - 0.026 13.5 9.2 0.22 10.5 2.3 2.3 1 1 0 2 2 2 0 RNA-binding signal recognition particle 68 DUF2225 PF09986.9 EON98036.1 - 0.026 14.2 8.1 0.61 9.8 0.3 2.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_20 PF14561.6 EON98036.1 - 0.064 13.6 7.0 0.86 10.0 2.8 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat APP_E2 PF12925.7 EON98036.1 - 0.092 12.5 7.9 1 9.1 0.2 3.0 1 1 1 3 3 3 0 E2 domain of amyloid precursor protein CCP_MauG PF03150.14 EON98036.1 - 0.23 12.1 1.1 4 8.1 0.1 2.4 2 1 0 2 2 2 0 Di-haem cytochrome c peroxidase TPR_10 PF13374.6 EON98036.1 - 0.26 11.2 9.8 14 5.7 0.7 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 EON98036.1 - 1.4 9.0 14.3 8.9 6.4 0.1 4.4 4 1 0 4 4 3 0 Tetratricopeptide repeat Homeobox_KN PF05920.11 EON98037.1 - 6.8e-22 77.1 0.6 1.3e-21 76.2 0.6 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EON98037.1 - 1.1e-08 34.8 1.0 2e-08 34.0 1.0 1.4 1 0 0 1 1 1 1 Homeodomain Tubulin_3 PF14881.6 EON98038.1 - 1.3e-82 275.8 0.1 1.9e-82 275.3 0.1 1.2 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 EON98038.1 - 7.9e-12 45.5 0.0 3.2e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain DUF719 PF05334.13 EON98038.1 - 5.3 7.2 5.2 80 3.4 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF719) HEAT PF02985.22 EON98039.1 - 5.9e-35 116.3 14.8 0.015 15.5 0.0 13.2 13 1 1 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 EON98039.1 - 6e-28 97.1 5.0 0.0016 18.8 0.0 8.8 3 3 6 9 9 9 8 HEAT repeats HEAT_EZ PF13513.6 EON98039.1 - 1.3e-13 51.2 2.5 0.011 16.3 0.1 8.3 8 2 2 10 10 9 2 HEAT-like repeat Cnd1 PF12717.7 EON98039.1 - 2.2e-12 47.3 12.5 2.3e-05 24.5 0.1 6.1 4 2 2 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EON98039.1 - 3.2e-10 40.5 5.8 0.028 15.0 0.1 7.2 4 1 5 9 9 9 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EON98039.1 - 1.7e-07 30.2 8.5 0.0061 15.2 0.2 5.0 3 2 3 6 6 6 3 Adaptin N terminal region CLASP_N PF12348.8 EON98039.1 - 2.3e-07 30.6 1.2 0.21 11.2 0.0 4.6 4 1 1 5 5 5 3 CLASP N terminal RTP1_C1 PF10363.9 EON98039.1 - 6.5e-06 26.3 5.3 0.61 10.3 0.3 5.2 4 1 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 Proteasom_PSMB PF10508.9 EON98039.1 - 0.053 12.0 3.8 0.27 9.7 0.1 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit DUF4864 PF16156.5 EON98039.1 - 0.11 13.1 1.0 1.6 9.5 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4864) Arm PF00514.23 EON98039.1 - 0.13 12.3 3.3 6.8 6.9 0.0 3.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat IFRD PF05004.13 EON98039.1 - 0.63 9.1 2.8 2.8 6.9 0.1 3.2 3 2 1 4 4 4 0 Interferon-related developmental regulator (IFRD) AAA_2 PF07724.14 EON98040.1 - 1.1e-46 159.0 0.0 3.4e-45 154.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EON98040.1 - 2.4e-34 117.4 12.9 1.2e-33 115.1 3.3 3.7 3 0 0 3 3 3 1 AAA lid domain AAA PF00004.29 EON98040.1 - 8.1e-27 94.2 0.0 2.1e-14 54.1 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EON98040.1 - 2.1e-24 85.4 0.6 1.3e-23 82.8 0.6 2.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EON98040.1 - 7.6e-16 58.4 0.0 5.5e-10 39.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EON98040.1 - 1.8e-13 51.2 6.4 3.3e-06 27.6 0.1 5.7 4 2 1 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 EON98040.1 - 6.4e-13 49.2 0.4 8.9e-05 22.8 0.0 4.7 3 2 1 4 4 3 2 AAA domain Sigma54_activat PF00158.26 EON98040.1 - 5.3e-09 36.0 0.0 2.3e-05 24.2 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 EON98040.1 - 1.4e-06 28.4 0.0 0.16 12.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 EON98040.1 - 3.7e-06 26.6 0.0 0.015 14.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 EON98040.1 - 3.8e-06 26.8 0.0 0.072 12.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Clp_N PF02861.20 EON98040.1 - 4.9e-06 26.6 4.1 0.00064 19.8 0.1 3.9 3 0 0 3 3 3 1 Clp amino terminal domain, pathogenicity island component AAA_18 PF13238.6 EON98040.1 - 6.2e-06 26.8 0.2 0.15 12.7 0.0 3.5 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 EON98040.1 - 7.4e-06 25.5 0.1 0.17 11.2 0.1 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EON98040.1 - 1.2e-05 25.5 0.0 0.27 11.4 0.0 3.2 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 EON98040.1 - 2.7e-05 24.2 5.6 0.056 13.4 0.1 4.7 4 1 0 4 4 3 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EON98040.1 - 6.9e-05 23.2 0.0 0.56 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 EON98040.1 - 0.00014 22.1 2.0 0.5 10.6 0.0 3.6 4 0 0 4 4 2 2 AAA domain RuvB_N PF05496.12 EON98040.1 - 0.00029 20.6 1.5 5.2 6.8 0.7 4.3 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EON98040.1 - 0.00032 20.6 0.0 1.6 8.6 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EON98040.1 - 0.00036 20.3 0.0 1.1 9.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EON98040.1 - 0.00036 20.3 0.0 0.56 9.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EON98040.1 - 0.00036 20.5 0.0 0.44 10.6 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EON98040.1 - 0.00046 20.1 0.0 0.56 10.1 0.0 3.0 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EON98040.1 - 0.00066 20.2 0.2 0.94 10.0 0.0 3.3 3 0 0 3 3 2 1 ABC transporter AAA_19 PF13245.6 EON98040.1 - 0.00082 19.7 2.7 0.34 11.3 0.1 4.0 5 1 0 5 5 3 1 AAA domain T2SSE PF00437.20 EON98040.1 - 0.0018 17.4 0.0 0.061 12.4 0.0 2.7 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 EON98040.1 - 0.0019 17.9 0.0 2 8.2 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain GAS PF13851.6 EON98040.1 - 0.0026 17.1 6.4 0.0091 15.4 6.4 1.9 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ResIII PF04851.15 EON98040.1 - 0.0032 17.5 0.0 0.87 9.6 0.0 3.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit NACHT PF05729.12 EON98040.1 - 0.0042 17.0 0.0 0.42 10.5 0.0 2.9 2 0 0 2 2 2 1 NACHT domain Roc PF08477.13 EON98040.1 - 0.0073 16.5 0.0 2.3 8.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Torsin PF06309.11 EON98040.1 - 0.0085 16.2 0.0 0.042 13.9 0.0 2.0 2 0 0 2 2 2 1 Torsin NTPase_1 PF03266.15 EON98040.1 - 0.012 15.5 0.1 0.33 10.9 0.0 3.0 3 0 0 3 3 2 0 NTPase Zeta_toxin PF06414.12 EON98040.1 - 0.013 14.8 0.0 1.4 8.2 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.15 EON98040.1 - 0.013 15.4 0.0 6.8 6.6 0.0 2.8 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 EON98040.1 - 0.021 14.5 0.0 4.4 6.9 0.0 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Macoilin PF09726.9 EON98040.1 - 0.038 12.6 7.1 0.072 11.7 7.1 1.4 1 0 0 1 1 1 0 Macoilin family V_ATPase_I PF01496.19 EON98040.1 - 0.057 11.3 1.4 0.12 10.2 1.4 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF815 PF05673.13 EON98040.1 - 0.059 12.5 0.0 4.6 6.3 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 EON98040.1 - 0.11 12.2 0.0 10 5.8 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EON98040.1 - 0.12 12.1 0.0 7.1 6.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 EON98040.1 - 0.13 11.9 3.0 5.4 6.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain Cep57_CLD_2 PF14197.6 EON98040.1 - 0.27 11.3 7.7 1 9.5 7.7 2.0 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 AAA_23 PF13476.6 EON98040.1 - 0.37 11.3 0.0 0.37 11.3 0.0 4.7 5 1 0 5 5 3 0 AAA domain CHDCT2 PF08074.11 EON98040.1 - 0.96 9.6 4.8 2.2 8.4 0.1 3.3 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain Spc7 PF08317.11 EON98040.1 - 1.5 7.6 10.3 3.5 6.4 10.3 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Ras PF00071.22 EON98042.1 - 6.6e-58 194.9 0.0 7.7e-58 194.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EON98042.1 - 3.4e-34 117.6 0.0 4.9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EON98042.1 - 1.8e-13 50.3 0.0 3.2e-13 49.5 0.0 1.3 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EON98042.1 - 5.9e-05 22.7 0.0 9.3e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EON98042.1 - 8e-05 22.7 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EON98042.1 - 0.00014 21.3 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EON98042.1 - 0.00095 19.6 0.0 0.0012 19.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EON98042.1 - 0.051 13.5 0.0 1.9 8.4 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase CAF1 PF04857.20 EON98043.1 - 3.1e-23 82.5 0.0 9.9e-11 41.4 0.0 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease RFX_DNA_binding PF02257.15 EON98043.1 - 0.15 12.7 0.0 0.49 11.1 0.0 1.9 2 0 0 2 2 2 0 RFX DNA-binding domain Amidohydro_3 PF07969.11 EON98044.1 - 1.1e-11 45.0 0.3 3.9e-11 43.1 0.2 1.8 1 1 1 2 2 2 1 Amidohydrolase family Amidohydro_1 PF01979.20 EON98044.1 - 2e-11 43.8 0.0 6.7e-11 42.1 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Ferric_reduct PF01794.19 EON98045.1 - 8.7e-23 80.8 10.5 1.3e-22 80.2 9.5 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EON98045.1 - 1.5e-19 70.6 0.0 9.8e-11 42.0 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EON98045.1 - 1.3e-13 51.0 0.0 1.9e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain Zeta_toxin PF06414.12 EON98047.1 - 4.1e-54 182.9 0.0 5.6e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 EON98047.1 - 0.00015 22.0 0.0 0.00033 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EON98047.1 - 0.0011 18.7 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 EON98047.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EON98047.1 - 0.032 14.5 0.0 0.079 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 EON98047.1 - 0.033 14.1 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Microtubule binding AAA_5 PF07728.14 EON98047.1 - 0.045 13.7 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 EON98047.1 - 0.057 13.4 0.1 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 EON98047.1 - 0.14 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Nup188_C PF18378.1 EON98048.1 - 6.1e-156 518.9 0.1 8.3e-156 518.5 0.1 1.2 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain CDC37_N PF03234.14 EON98049.1 - 1e-50 171.9 0.7 1e-50 171.9 0.7 3.3 3 1 1 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EON98049.1 - 8.7e-43 145.0 0.1 1.9e-42 143.9 0.1 1.6 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EON98049.1 - 1.4e-33 114.9 4.7 1.4e-33 114.9 4.7 2.6 2 0 0 2 2 2 1 Cdc37 C terminal domain Spectrin PF00435.21 EON98049.1 - 0.0048 17.4 1.2 0.0048 17.4 1.2 2.9 3 0 0 3 3 3 1 Spectrin repeat hGDE_central PF14702.6 EON98049.1 - 0.02 14.6 0.1 0.06 13.0 0.1 1.8 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme DUF948 PF06103.11 EON98049.1 - 6.5 7.1 5.2 7.2 6.9 0.2 3.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) AhpC-TSA_2 PF13911.6 EON98050.1 - 7.7e-07 29.2 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EON98050.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Rtf2 PF04641.12 EON98050.1 - 0.088 12.2 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger KTI12 PF08433.10 EON98051.1 - 2.1e-67 227.4 0.0 3.3e-67 226.8 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EON98051.1 - 0.00025 21.2 0.4 0.00054 20.1 0.4 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EON98051.1 - 0.0024 18.2 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EON98051.1 - 0.0067 17.0 0.2 0.029 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain ThiF PF00899.21 EON98052.1 - 5.8e-28 97.9 0.0 7.8e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family NUDIX_2 PF13869.6 EON98054.1 - 6.9e-79 263.8 0.0 8.4e-79 263.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase CLU PF13236.6 EON98055.1 - 1.6e-77 260.3 0.0 2.7e-77 259.5 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EON98055.1 - 1.6e-53 181.3 0.0 3.9e-53 180.1 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EON98055.1 - 1.1e-28 99.3 9.7 7.3e-13 48.6 0.1 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EON98055.1 - 2.1e-25 87.8 2.2 1.9e-06 27.5 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat CLU_N PF15044.6 EON98055.1 - 1.9e-23 82.6 0.1 4.8e-23 81.3 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_8 PF13181.6 EON98055.1 - 4e-07 29.7 5.7 0.01 16.0 0.3 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EON98055.1 - 0.00012 21.9 9.6 0.27 11.5 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF727 PF05303.12 EON98055.1 - 0.0087 16.1 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_17 PF13431.6 EON98055.1 - 0.085 13.3 2.3 93 3.8 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EON98055.1 - 0.089 12.9 2.8 4.2 7.6 0.0 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EON98055.1 - 0.13 12.1 2.0 18 5.3 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EON98055.1 - 0.14 11.5 6.4 0.45 9.8 5.8 1.8 1 1 0 1 1 1 0 MalT-like TPR region Yippee-Mis18 PF03226.14 EON98056.1 - 9.7e-17 61.1 0.5 1.1e-16 61.0 0.5 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EON98056.1 - 0.0013 19.0 1.4 0.0019 18.4 1.4 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I Kri1 PF05178.12 EON98057.1 - 2.6e-30 105.0 20.5 2.6e-30 105.0 20.5 4.8 4 2 1 5 5 5 1 KRI1-like family Kri1_C PF12936.7 EON98057.1 - 4.9e-29 100.4 0.3 4.9e-29 100.4 0.3 3.5 3 1 0 3 3 3 1 KRI1-like family C-terminal PVL_ORF50 PF07768.11 EON98057.1 - 0.5 10.7 0.1 0.5 10.7 0.1 4.5 3 1 1 5 5 5 0 PVL ORF-50-like family SMC_N PF02463.19 EON98058.1 - 2.6e-62 210.1 0.0 4.2e-62 209.5 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EON98058.1 - 2.5e-24 85.8 0.0 7.8e-24 84.2 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EON98058.1 - 1.4e-20 74.6 3.0 1.4e-20 74.6 3.0 6.9 2 2 2 4 4 1 1 AAA domain AAA_15 PF13175.6 EON98058.1 - 6e-16 59.1 3.4 6e-16 59.1 3.4 4.4 2 2 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 EON98058.1 - 1.5e-15 57.8 6.9 1.9e-07 31.2 0.9 3.2 2 2 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EON98058.1 - 0.0039 16.9 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.6 EON98058.1 - 0.0047 16.3 5.9 0.0047 16.3 5.9 7.4 3 2 3 6 6 4 1 Growth-arrest specific micro-tubule binding Arteri_GP4 PF02497.15 EON98058.1 - 0.0053 16.9 0.0 0.023 14.8 0.0 1.9 2 0 0 2 2 2 1 Arterivirus glycoprotein SbcCD_C PF13558.6 EON98058.1 - 0.0069 16.6 0.0 0.022 15.0 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EON98058.1 - 0.38 11.3 0.0 0.38 11.3 0.0 6.8 3 2 0 3 3 1 0 ABC transporter EDR1 PF14381.6 EON98058.1 - 1.2 8.9 9.2 0.21 11.3 2.8 3.0 3 0 0 3 3 3 0 Ethylene-responsive protein kinase Le-CTR1 CCP_MauG PF03150.14 EON98058.1 - 5.6 7.6 6.8 31 5.2 0.0 4.1 3 1 1 4 4 4 0 Di-haem cytochrome c peroxidase PCI PF01399.27 EON98058.1 - 7.3 7.2 7.6 4.5 7.8 0.3 3.6 1 1 2 3 3 3 0 PCI domain Prp18 PF02840.15 EON98059.1 - 1.3e-53 180.9 0.0 1.3e-53 180.9 0.0 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 EON98059.1 - 1.1e-11 44.0 3.2 1.1e-11 44.0 3.2 2.8 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like DUF1308 PF07000.11 EON98059.1 - 0.01 15.8 1.8 0.02 14.8 1.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) DUF966 PF06136.13 EON98059.1 - 0.059 13.1 10.2 0.077 12.7 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DDHD PF02862.17 EON98059.1 - 0.071 13.3 1.9 0.08 13.1 1.9 1.2 1 0 0 1 1 1 0 DDHD domain Nop14 PF04147.12 EON98059.1 - 0.21 9.8 23.8 0.26 9.5 23.8 1.1 1 0 0 1 1 1 0 Nop14-like family Selenoprotein_S PF06936.11 EON98059.1 - 0.74 9.6 14.4 1.3 8.8 14.4 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) Dsh_C PF12316.8 EON98059.1 - 0.84 10.0 9.0 1.3 9.4 9.0 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CDC27 PF09507.10 EON98059.1 - 2.2 7.6 21.8 3.1 7.1 21.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1996 PF09362.10 EON98060.1 - 1.4e-49 169.2 1.1 2e-49 168.7 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 EON98060.1 - 5.7e-18 64.9 9.9 1.5e-17 63.6 9.9 1.8 1 0 0 1 1 1 1 WSC domain DUF4766 PF15973.5 EON98060.1 - 0.04 14.5 4.2 0.039 14.5 2.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4766) ATF7IP_BD PF16788.5 EON98061.1 - 3.8 7.5 5.6 7.6 6.6 5.6 1.4 1 0 0 1 1 1 0 ATF-interacting protein binding domain tRNA_synthFbeta PF17759.1 EON98062.1 - 1.4e-45 155.4 0.0 2.1e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EON98062.1 - 5e-31 106.8 0.8 5.8e-30 103.4 0.1 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EON98062.1 - 1.2e-25 90.2 0.1 2e-25 89.5 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EON98062.1 - 1.2e-18 67.1 0.0 1.8e-15 57.0 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetase B5 domain PEP_mutase PF13714.6 EON98063.1 - 1.4e-43 149.1 4.6 1.6e-43 148.9 4.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EON98063.1 - 2.7e-18 65.8 1.7 3.4e-18 65.4 1.7 1.1 1 0 0 1 1 1 1 Isocitrate lyase family EIIBC-GUT_N PF03612.14 EON98063.1 - 0.039 13.7 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus ANAPC3 PF12895.7 EON98064.1 - 1.8e-23 82.5 5.6 3.8e-23 81.5 2.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EON98064.1 - 1.3e-06 28.6 2.3 0.0055 17.0 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EON98064.1 - 3.4e-05 23.6 6.7 0.013 15.6 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EON98064.1 - 6.4e-05 23.5 2.2 0.85 10.3 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EON98064.1 - 8e-05 23.1 5.9 0.1 13.5 0.0 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EON98064.1 - 8.8e-05 22.9 0.5 0.57 10.9 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EON98064.1 - 9.9e-05 22.3 5.3 0.023 14.9 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EON98064.1 - 0.00014 21.6 1.9 0.0047 16.7 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EON98064.1 - 0.0033 17.9 2.2 0.25 11.9 0.3 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EON98064.1 - 0.026 14.5 0.3 5.1 7.4 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Pro_isomerase PF00160.21 EON98065.1 - 4.1e-50 170.1 0.1 7.6e-50 169.3 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 EON98065.1 - 1.5e-05 25.1 0.0 5.7e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-NOSIP PF15906.5 EON98065.1 - 0.00047 20.2 0.0 0.0015 18.6 0.0 1.9 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein RRM_1 PF00076.22 EON98066.1 - 4.6e-16 58.4 0.0 6.6e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GST_N PF02798.20 EON98067.1 - 2.9e-13 50.0 0.0 5.3e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EON98067.1 - 1.9e-09 37.8 0.0 3.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EON98067.1 - 1.3e-07 31.7 0.0 2.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EON98067.1 - 2.6e-07 30.8 0.0 5.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EON98067.1 - 7.5e-05 22.7 0.0 0.0002 21.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EON98067.1 - 0.0011 19.1 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EON98067.1 - 0.17 12.6 0.0 0.49 11.2 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Peptidase_M24 PF00557.24 EON98068.1 - 1.5e-57 194.7 0.2 2.1e-57 194.2 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EON98068.1 - 2.7e-21 75.6 0.0 9.7e-21 73.8 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain SAM_2 PF07647.17 EON98069.1 - 2.6e-09 37.0 0.1 4.9e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EON98069.1 - 6.4e-05 23.3 0.3 0.00013 22.4 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 EON98069.1 - 0.011 15.8 0.3 0.029 14.5 0.2 1.7 2 0 0 2 2 2 0 IGR protein motif DUF4508 PF14969.6 EON98069.1 - 0.1 12.9 0.1 0.28 11.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Nop25 PF09805.9 EON98070.1 - 0.041 14.3 5.7 0.075 13.5 5.7 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CSRNP_N PF16019.5 EON98070.1 - 0.2 11.6 1.5 0.32 10.9 1.5 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Ndc1_Nup PF09531.10 EON98070.1 - 7.1 5.2 6.6 27 3.3 4.9 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup PI3_PI4_kinase PF00454.27 EON98071.1 - 6.9e-35 121.0 0.0 5.8e-34 118.0 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 EON98071.1 - 0.03 13.6 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) CXCR4_N PF12109.8 EON98071.1 - 0.09 13.0 0.1 0.97 9.7 0.0 2.5 2 0 0 2 2 2 0 CXCR4 Chemokine receptor N terminal SBDS_C PF09377.10 EON98072.1 - 3.5e-46 156.0 0.0 5.4e-46 155.4 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EON98072.1 - 3.5e-34 116.7 0.1 6.5e-34 115.9 0.1 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XAF1_C PF18608.1 EON98073.1 - 0.043 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 XIAP-associated factor 1 C-terminal domain DUF3397 PF11877.8 EON98074.1 - 0.4 10.9 11.5 0.086 13.1 2.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3397) CBP_BcsF PF11120.8 EON98074.1 - 1.2 9.3 6.5 0.4 10.8 0.3 2.7 2 1 0 2 2 2 0 Cellulose biosynthesis protein BcsF DUF1772 PF08592.11 EON98074.1 - 5.7 7.2 7.4 6.9 7.0 1.2 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) RhoGAP PF00620.27 EON98075.1 - 9.7e-39 132.6 0.0 1.5e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Pkinase PF00069.25 EON98076.1 - 2.8e-09 36.7 0.7 4.1e-09 36.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON98076.1 - 0.00038 19.8 0.0 0.00038 19.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase LpxI_C PF06230.11 EON98076.1 - 0.17 11.7 3.9 0.12 12.3 0.4 2.3 2 1 0 2 2 2 0 LpxI C-terminal domain Defensin_propep PF00879.18 EON98076.1 - 2.4 8.5 8.4 6.3 7.2 8.4 1.6 1 0 0 1 1 1 0 Defensin propeptide Rtf2 PF04641.12 EON98076.1 - 4.2 6.6 11.1 5.7 6.2 11.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Casc1_N PF15927.5 EON98076.1 - 6.9 6.3 15.1 10 5.7 15.1 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Ribosomal_S13 PF00416.22 EON98077.1 - 4.4e-56 188.8 3.2 5.1e-56 188.6 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EON98077.1 - 0.017 13.9 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.9 EON98077.1 - 0.13 12.7 0.4 0.34 11.4 0.4 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Methyltransf_28 PF02636.17 EON98078.1 - 2.6e-47 161.7 0.0 2.1e-32 112.8 0.0 2.1 1 1 1 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase Gtr1_RagA PF04670.12 EON98079.1 - 2e-52 177.9 0.2 2.4e-52 177.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF3982 PF13138.6 EON98080.1 - 0.15 11.9 0.2 0.36 10.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3982) CdvA PF18822.1 EON98082.1 - 0.0031 17.3 0.3 0.0076 16.1 0.1 1.7 2 0 0 2 2 2 1 CdvA-like coiled-coil domain FAD_binding_6 PF00970.24 EON98083.1 - 6.3e-30 103.5 0.0 9.8e-30 102.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EON98083.1 - 3e-27 95.4 0.0 4.4e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EON98083.1 - 0.00033 20.8 0.0 0.028 14.5 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF639 PF04842.12 EON98083.1 - 0.21 11.0 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Lung_7-TM_R PF06814.13 EON98085.1 - 1.4e-69 234.6 18.5 1.8e-69 234.3 18.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor EMP24_GP25L PF01105.24 EON98085.1 - 0.19 11.7 0.1 0.39 10.6 0.1 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF1980 PF09323.10 EON98085.1 - 1.5 8.7 4.4 1 9.2 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) FtsH_ext PF06480.15 EON98085.1 - 4.5 7.7 4.7 1.4 9.3 0.8 2.2 2 0 0 2 2 2 0 FtsH Extracellular Alg6_Alg8 PF03155.15 EON98086.1 - 2.2e-177 590.9 25.9 2.6e-177 590.7 25.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Peptidase_S10 PF00450.22 EON98087.1 - 2.8e-130 435.5 0.2 3.5e-130 435.2 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 EON98087.1 - 5.6e-19 68.9 0.2 1.3e-18 67.7 0.2 1.6 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Herpes_UL73 PF03554.13 EON98089.1 - 0.25 11.4 2.5 0.74 9.9 0.1 2.6 2 1 1 3 3 3 0 UL73 viral envelope glycoprotein His_biosynth PF00977.21 EON98090.1 - 1.8e-36 125.7 0.0 2.2e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 EON98090.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family M20_dimer PF07687.14 EON98091.1 - 4.2e-13 49.2 0.0 9.7e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EON98091.1 - 3.2e-10 40.1 0.1 4.8e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 MFS_1 PF07690.16 EON98092.1 - 1.4e-32 113.0 26.7 2.2e-32 112.4 26.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Acyl_transf_3 PF01757.22 EON98092.1 - 2.8 6.9 37.2 0.085 11.9 14.5 2.8 2 1 1 3 3 3 0 Acyltransferase family Lectin_leg-like PF03388.13 EON98093.1 - 3.6e-22 78.8 0.0 6.1e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family Baculo_PEP_C PF04513.12 EON98093.1 - 0.019 15.0 1.2 0.054 13.5 1.2 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spore_YpjB PF09577.10 EON98093.1 - 0.068 13.0 0.2 0.39 10.5 0.0 1.9 1 1 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) Not3 PF04065.15 EON98093.1 - 0.076 12.4 0.9 0.11 11.9 0.9 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Leu_zip PF15294.6 EON98093.1 - 0.2 11.2 3.8 0.29 10.6 3.8 1.1 1 0 0 1 1 1 0 Leucine zipper Atg14 PF10186.9 EON98093.1 - 0.25 10.4 2.3 0.35 9.9 2.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Kelch_2 PF07646.15 EON98093.1 - 1 9.5 3.2 12 6.1 0.3 2.5 2 0 0 2 2 2 0 Kelch motif TolA_bind_tri PF16331.5 EON98093.1 - 2.2 8.4 5.1 4.7 7.4 0.1 3.1 3 0 0 3 3 3 0 TolA binding protein trimerisation K_trans PF02705.16 EON98094.1 - 1.3e-181 604.8 13.3 1.6e-181 604.4 13.3 1.1 1 0 0 1 1 1 1 K+ potassium transporter zf-Tim10_DDP PF02953.15 EON98095.1 - 2.3e-19 68.8 5.4 3e-19 68.4 5.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2431 PF10354.9 EON98096.1 - 1.1e-65 221.0 0.0 1.4e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Laminin_I PF06008.14 EON98097.1 - 0.01 15.6 7.5 0.016 14.9 7.5 1.3 1 0 0 1 1 1 0 Laminin Domain I Golgin_A5 PF09787.9 EON98097.1 - 0.017 14.6 12.3 0.024 14.1 12.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 ADIP PF11559.8 EON98097.1 - 0.027 14.5 6.4 0.062 13.4 6.4 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 EON98097.1 - 0.06 12.9 2.0 0.081 12.5 2.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit YscO PF07321.12 EON98097.1 - 0.081 12.9 18.7 1.6 8.6 16.8 2.2 2 0 0 2 2 2 0 Type III secretion protein YscO Med9 PF07544.13 EON98097.1 - 0.22 11.7 4.0 0.22 11.6 1.8 2.0 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 UPF0242 PF06785.11 EON98097.1 - 0.46 10.6 4.8 0.88 9.6 4.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1682 PF07946.14 EON98097.1 - 0.56 9.4 9.6 0.79 8.9 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Atg14 PF10186.9 EON98097.1 - 0.57 9.2 6.9 1 8.4 6.9 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EON98097.1 - 0.85 8.8 4.4 1.2 8.3 4.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein Phage_GP20 PF06810.11 EON98097.1 - 1.1 9.1 8.6 1.1 9.1 7.3 1.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 SlyX PF04102.12 EON98097.1 - 2.5 8.8 7.1 25 5.6 3.9 3.0 3 1 0 3 3 3 0 SlyX GBP_C PF02841.14 EON98097.1 - 2.6 7.3 12.9 4 6.8 12.9 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain ZapB PF06005.12 EON98097.1 - 6.5 7.3 0.0 6.5 7.3 0.0 3.2 2 1 1 3 3 2 0 Cell division protein ZapB Nup188 PF10487.9 EON98098.1 - 5.7e-16 57.7 1.0 9.1e-16 57.0 1.0 1.3 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Pro-kuma_activ PF09286.11 EON98099.1 - 2.2e-31 109.1 0.0 3.1e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Titin_Ig-rpts PF06582.12 EON98099.1 - 0.36 10.8 1.9 22 5.1 0.0 3.0 3 0 0 3 3 3 0 Titin repeat Rhodanese PF00581.20 EON98100.1 - 3.9e-08 33.8 0.0 9.8e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain DUF4125 PF13526.6 EON98100.1 - 0.079 12.6 1.1 0.14 11.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4125) Glyco_transf_22 PF03901.17 EON98101.1 - 3.5e-14 52.9 0.5 4.2e-14 52.6 0.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family LigD_N PF13298.6 EON98101.1 - 0.097 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) Adap_comp_sub PF00928.21 EON98102.1 - 6.9e-19 68.2 0.0 9.1e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EON98102.1 - 5.5e-08 32.8 0.1 9.2e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 EON98102.1 - 0.0065 16.9 0.4 0.013 15.9 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) UPF0047 PF01894.17 EON98103.1 - 1.1e-36 125.5 0.0 1.7e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Peptidase_C2 PF00648.21 EON98104.1 - 9.4e-28 97.1 0.0 1.4e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EON98104.1 - 6.2e-10 39.5 0.0 0.0017 18.6 0.0 3.5 3 0 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.18 EON98104.1 - 0.0019 18.2 2.9 0.0033 17.5 2.9 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF1490 PF07371.12 EON98104.1 - 0.33 11.1 1.8 0.73 10.0 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) PIG-X PF08320.12 EON98105.1 - 8.2e-69 231.7 0.0 1.4e-68 231.0 0.0 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 E1-E2_ATPase PF00122.20 EON98106.1 - 2.5e-39 134.7 6.2 1.1e-38 132.6 0.3 3.6 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EON98106.1 - 5.1e-18 66.1 0.0 1.1e-17 65.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EON98106.1 - 1.8e-10 40.4 0.0 5.3e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EON98106.1 - 0.003 17.3 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EON98106.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) AphA_like PF14557.6 EON98106.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator BRE1 PF08647.11 EON98107.1 - 9.8e-28 96.1 9.8 9.8e-28 96.1 9.8 6.0 4 2 1 5 5 3 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 EON98107.1 - 9.3e-09 35.0 7.0 1.4e-08 34.4 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EON98107.1 - 1.4e-08 34.4 7.6 2.5e-08 33.6 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EON98107.1 - 2.2e-08 33.8 9.2 3.9e-08 33.0 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EON98107.1 - 6.1e-08 32.4 6.8 1e-07 31.7 6.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EON98107.1 - 2.5e-07 30.5 9.5 4.2e-07 29.8 9.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EON98107.1 - 1.7e-06 28.3 7.9 2.7e-06 27.6 7.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EON98107.1 - 2.4e-06 27.4 8.0 5.1e-06 26.4 8.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EON98107.1 - 0.00043 20.4 6.5 0.00087 19.4 6.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING JIP_LZII PF16471.5 EON98107.1 - 0.0019 18.3 3.5 0.0019 18.3 3.5 6.4 6 2 2 8 8 7 1 JNK-interacting protein leucine zipper II Prefoldin_2 PF01920.20 EON98107.1 - 0.0065 16.4 9.0 0.0065 16.4 9.0 7.5 6 3 1 7 7 7 1 Prefoldin subunit zf-RING_6 PF14835.6 EON98107.1 - 0.0066 16.3 3.6 0.013 15.3 3.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 EON98107.1 - 0.018 15.4 6.1 0.073 13.4 6.1 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain DivIC PF04977.15 EON98107.1 - 0.022 14.5 1.5 0.022 14.5 1.5 8.9 4 2 5 10 10 9 0 Septum formation initiator zf-C2H2_6 PF13912.6 EON98107.1 - 0.16 12.0 1.7 0.38 10.8 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zinc-ribbons_6 PF07191.12 EON98107.1 - 1.4 9.0 6.2 1.2 9.2 2.3 2.2 1 1 1 2 2 2 0 zinc-ribbons zf-RING_4 PF14570.6 EON98107.1 - 1.4 8.8 5.8 7.8 6.4 6.3 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C2H2_jaz PF12171.8 EON98107.1 - 1.7 9.0 7.2 6.9 7.1 0.4 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-RING_11 PF17123.5 EON98107.1 - 2.3 8.0 4.1 5.4 6.9 4.1 1.7 1 0 0 1 1 1 0 RING-like zinc finger FYVE PF01363.21 EON98107.1 - 4.2 7.6 11.0 48 4.2 11.2 2.3 1 1 1 2 2 2 0 FYVE zinc finger TPR_8 PF13181.6 EON98108.1 - 4.1e-15 54.7 9.8 0.0036 17.4 0.0 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 EON98108.1 - 5.9e-10 39.6 15.0 0.037 14.7 1.8 6.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EON98108.1 - 2.9e-09 36.7 4.0 0.034 14.5 0.1 7.6 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EON98108.1 - 7e-09 35.1 28.8 0.0057 16.7 0.0 9.5 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_14 PF13428.6 EON98108.1 - 8.5e-08 32.4 18.3 0.26 12.2 0.0 9.8 9 1 1 10 10 9 1 Tetratricopeptide repeat TPR_20 PF14561.6 EON98108.1 - 5.8e-07 29.8 13.0 0.017 15.5 1.8 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EON98108.1 - 5.9e-07 29.1 7.3 0.29 10.8 0.0 5.3 5 1 1 6 6 6 3 TPR repeat TPR_1 PF00515.28 EON98108.1 - 4e-06 26.4 20.5 0.025 14.4 0.0 6.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 EON98108.1 - 6.3e-05 22.7 8.0 0.092 12.8 1.6 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EON98108.1 - 0.0036 17.8 17.8 6 7.5 0.3 7.3 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 EON98108.1 - 0.0038 17.4 10.7 0.77 10.0 0.1 6.2 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EON98108.1 - 0.0085 16.7 15.5 0.37 11.5 0.2 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 EON98108.1 - 0.01 16.1 16.4 1.2 9.5 0.8 6.3 6 1 1 7 7 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EON98108.1 - 0.76 10.2 3.7 18 5.8 0.1 3.5 4 0 0 4 4 2 0 Alkyl sulfatase dimerisation ANAPC3 PF12895.7 EON98108.1 - 4.9 7.5 21.9 3.5 7.9 0.1 6.8 8 1 0 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 Ribosomal_S3_C PF00189.20 EON98109.1 - 8.4e-25 87.1 0.2 5.4e-24 84.5 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EON98109.1 - 5.6e-12 45.3 0.1 1.1e-11 44.4 0.1 1.5 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 EON98109.1 - 0.077 12.8 0.2 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 Coilin N-terminus UN_NPL4 PF11543.8 EON98109.1 - 0.097 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Aminotran_3 PF00202.21 EON98110.1 - 1.5e-118 396.0 0.0 1.7e-118 395.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EON98110.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Mito_carr PF00153.27 EON98111.1 - 3e-51 171.3 0.3 1.4e-16 60.2 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein PAP_central PF04928.17 EON98112.1 - 5e-107 356.5 0.0 6.7e-107 356.1 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EON98112.1 - 1.1e-64 217.2 0.3 2.1e-64 216.3 0.3 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EON98112.1 - 1.1e-10 41.7 0.0 2.4e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Peptidase_S49 PF01343.18 EON98112.1 - 0.0068 16.4 0.1 0.018 15.0 0.1 1.7 1 0 0 1 1 1 1 Peptidase family S49 TM1586_NiRdase PF14512.6 EON98112.1 - 0.055 13.0 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative TM nitroreductase Sedlin_N PF04628.13 EON98113.1 - 3.3e-44 150.2 0.0 3.8e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EON98113.1 - 0.00085 19.3 0.1 0.037 13.9 0.0 2.1 1 1 1 2 2 2 1 Sybindin-like family DUF1801 PF08818.11 EON98113.1 - 0.064 13.8 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DU1801) IGPS PF00218.21 EON98114.1 - 1.2e-97 326.1 0.0 2.6e-97 325.0 0.0 1.6 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 EON98114.1 - 8.6e-47 159.4 0.0 2.3e-46 157.9 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 EON98114.1 - 8.9e-41 139.8 1.0 3.6e-40 137.8 0.0 2.3 2 0 0 2 2 2 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 EON98114.1 - 0.00014 21.6 0.2 0.00054 19.8 0.2 1.9 1 1 0 1 1 1 1 Peptidase C26 BRCT_2 PF16589.5 EON98114.1 - 0.00018 21.8 0.1 0.00045 20.6 0.1 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EON98114.1 - 0.00068 19.9 0.0 0.0019 18.5 0.0 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain QRPTase_C PF01729.19 EON98114.1 - 0.0094 15.7 1.3 0.073 12.8 0.1 2.7 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain BRCT PF00533.26 EON98114.1 - 0.079 13.4 0.0 0.26 11.7 0.0 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain FMN_dh PF01070.18 EON98114.1 - 0.082 11.9 0.1 0.24 10.4 0.2 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase DEAD PF00270.29 EON98115.1 - 1.1e-38 132.7 0.4 2.1e-38 131.9 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON98115.1 - 1.3e-31 109.2 0.2 8.1e-30 103.4 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON98115.1 - 5.6e-06 26.5 0.5 1.1e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FAM110_C PF14160.6 EON98115.1 - 0.044 14.8 0.1 6.6 7.9 0.0 2.5 2 0 0 2 2 2 0 Centrosome-associated C terminus CMS1 PF14617.6 EON98115.1 - 0.66 9.3 9.0 0.37 10.1 0.1 2.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit CENP-T_C PF15511.6 EON98116.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EON98116.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EON98116.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EON98116.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EON98116.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EON98116.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EON98116.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EON98116.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 EON98116.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Peptidase_M16_M PF16187.5 EON98117.1 - 6e-102 340.7 0.7 1e-101 339.9 0.7 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 EON98117.1 - 4.2e-42 144.2 0.1 7e-22 78.3 0.0 3.5 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EON98117.1 - 3e-33 114.9 1.0 2e-32 112.3 0.0 2.6 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) DUF1451 PF07295.11 EON98117.1 - 3.6 7.6 8.8 0.44 10.6 2.2 2.6 2 1 1 3 3 3 0 Zinc-ribbon containing domain NDUF_B4 PF07225.12 EON98118.1 - 4.2e-05 23.4 0.1 4.2e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) HOOK PF05622.12 EON98119.1 - 0.038 12.1 18.0 0.068 11.3 18.0 1.3 1 1 0 1 1 1 0 HOOK protein GldM_N PF12081.8 EON98119.1 - 0.052 13.6 10.3 0.55 10.3 4.8 2.1 1 1 1 2 2 2 0 GldM N-terminal domain Jnk-SapK_ap_N PF09744.9 EON98119.1 - 0.076 13.2 20.6 0.049 13.8 13.5 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TLE_N PF03920.15 EON98119.1 - 0.11 12.6 2.3 0.13 12.4 1.3 1.7 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain DUF2617 PF10936.8 EON98119.1 - 0.14 12.2 1.2 0.37 10.8 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF2617 SlyX PF04102.12 EON98119.1 - 0.28 11.8 0.2 0.28 11.8 0.2 3.5 4 0 0 4 4 3 0 SlyX FAM167 PF11652.8 EON98119.1 - 0.4 11.2 3.7 1.9 9.0 0.5 3.0 3 1 1 4 4 4 0 FAM167 DUF2420 PF10336.9 EON98119.1 - 0.41 10.7 2.9 1 9.4 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2420) Fzo_mitofusin PF04799.13 EON98119.1 - 0.69 9.4 10.6 0.96 9.0 2.5 2.7 1 1 2 3 3 3 0 fzo-like conserved region Phage_GPO PF05929.11 EON98119.1 - 1.1 8.8 13.3 1 8.9 6.8 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.6 EON98119.1 - 2.3 7.5 11.6 13 5.0 11.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Cytochrom_C_2 PF01322.20 EON98119.1 - 3 8.8 8.4 3.8 8.4 5.3 2.2 1 1 0 2 2 2 0 Cytochrome C' PRKG1_interact PF15898.5 EON98119.1 - 4.3 8.3 20.5 3.6 8.6 10.4 2.9 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Exonuc_VII_L PF02601.15 EON98119.1 - 4.4 6.8 13.3 5.9 6.4 13.3 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit TnpV PF14198.6 EON98119.1 - 8.9 6.3 9.3 33 4.5 0.3 2.6 1 1 1 2 2 2 0 Transposon-encoded protein TnpV Mg_trans_NIPA PF05653.14 EON98120.1 - 4e-101 338.0 13.8 4.8e-101 337.8 13.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EON98120.1 - 9.4e-07 29.1 29.5 6e-05 23.2 6.6 3.1 3 0 0 3 3 3 3 EamA-like transporter family MARVEL PF01284.23 EON98120.1 - 0.86 9.6 13.1 28 4.7 1.1 2.6 1 1 1 2 2 2 0 Membrane-associating domain AgrB PF04647.15 EON98120.1 - 1.1 8.5 15.9 0.88 8.9 7.0 3.2 1 1 3 4 4 4 0 Accessory gene regulator B Acyl_transf_3 PF01757.22 EON98120.1 - 6.3 5.8 16.6 70 2.3 13.1 2.3 1 1 1 2 2 2 0 Acyltransferase family DUF4293 PF14126.6 EON98120.1 - 8 6.7 10.7 7.4 6.8 9.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Methyltr_RsmB-F PF01189.17 EON98121.1 - 9.6e-16 58.0 0.0 5.8e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F UCH PF00443.29 EON98122.1 - 4.9e-54 183.5 0.0 7.3e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EON98122.1 - 6e-08 32.6 0.0 0.00041 20.0 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Septin PF00735.18 EON98123.1 - 1.1e-09 38.0 0.0 2.6e-08 33.5 0.0 2.1 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EON98123.1 - 0.00035 20.6 0.0 0.0011 19.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EON98123.1 - 0.0027 18.1 0.0 0.011 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EON98123.1 - 0.013 15.4 0.0 0.035 14.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 EON98123.1 - 0.018 15.1 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 EON98123.1 - 0.018 15.3 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 EON98123.1 - 0.022 15.2 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EON98123.1 - 0.022 14.6 0.0 0.079 12.9 0.0 1.9 2 0 0 2 2 1 0 RsgA GTPase DUF815 PF05673.13 EON98123.1 - 0.024 13.8 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MCM PF00493.23 EON98123.1 - 0.029 13.5 0.0 0.091 11.8 0.0 1.8 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 EON98123.1 - 0.037 14.5 0.0 0.088 13.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EON98123.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EON98123.1 - 0.08 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 EON98123.1 - 0.11 12.2 0.4 0.41 10.4 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain SPATA6 PF14909.6 EON98123.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.6 2 0 0 2 2 1 0 Spermatogenesis-assoc protein 6 Sigma54_activat PF00158.26 EON98123.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Hpr_kinase_C PF07475.12 EON98123.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain DUF1899 PF08953.11 EON98124.1 - 8.3e-35 118.5 0.1 1.6e-34 117.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EON98124.1 - 3.1e-19 68.6 0.1 5.8e-19 67.7 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EON98124.1 - 8.2e-18 64.5 5.9 3.1e-05 24.7 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON98124.1 - 8.3e-07 29.2 0.0 0.0029 17.9 0.0 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EON98124.1 - 0.0035 16.1 0.1 0.15 10.7 0.1 2.2 1 1 1 2 2 2 1 Nucleoporin Nup120/160 eIF2A PF08662.11 EON98124.1 - 0.021 14.7 0.0 1.5 8.6 0.0 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Spc7 PF08317.11 EON98124.1 - 0.16 10.8 5.5 0.099 11.5 3.2 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF16 PF01519.16 EON98124.1 - 0.29 11.6 2.7 0.68 10.4 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 TMPIT PF07851.13 EON98124.1 - 1.4 8.1 2.3 2.1 7.5 2.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein HrpB7 PF09486.10 EON98124.1 - 2.7 8.4 10.9 0.97 9.8 2.5 2.7 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF2985 PF11204.8 EON98125.1 - 1.4e-38 130.9 1.1 1.4e-38 130.9 1.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Phage_holin_3_6 PF07332.11 EON98125.1 - 0.44 10.6 2.4 0.79 9.8 0.0 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III FHA PF00498.26 EON98126.1 - 3e-12 46.7 0.1 7.3e-12 45.5 0.0 1.7 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EON98126.1 - 5.3e-05 23.5 0.0 0.00024 21.4 0.0 2.0 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain MR_MLE_C PF13378.6 EON98127.1 - 2.1e-56 191.0 0.6 5.1e-56 189.7 0.1 1.9 2 0 0 2 2 2 1 Enolase C-terminal domain-like WD40 PF00400.32 EON98127.1 - 1.9e-11 44.3 12.1 0.0047 17.7 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON98127.1 - 0.00016 21.9 0.0 2.6 8.4 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Sporozoite_P67 PF05642.11 EON98127.1 - 0.032 12.3 3.5 0.067 11.3 3.5 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ge1_WD40 PF16529.5 EON98127.1 - 0.12 11.3 0.0 1.4 7.8 0.0 2.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cwf_Cwc_15 PF04889.12 EON98127.1 - 0.29 10.8 7.2 0.48 10.1 7.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Astro_capsid_p PF12226.8 EON98127.1 - 3.1 6.9 6.1 4.6 6.3 6.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pes-10 PF07149.11 EON98127.1 - 5.4 6.0 5.3 8.7 5.3 5.3 1.2 1 0 0 1 1 1 0 Pes-10 SRI PF08236.11 EON98128.1 - 1.7e-21 76.2 12.9 5.3e-21 74.6 12.9 1.9 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 EON98128.1 - 2.7e-18 66.9 0.1 2.7e-18 66.9 0.1 4.3 4 2 0 4 4 4 1 SET domain AWS PF17907.1 EON98128.1 - 3.8e-13 49.2 11.9 3.8e-13 49.2 11.9 2.3 2 0 0 2 2 2 1 AWS domain WW PF00397.26 EON98128.1 - 9.1e-06 25.7 0.7 2.1e-05 24.5 0.7 1.7 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 EON98128.1 - 1.3e-05 25.1 0.3 5.5e-05 23.1 0.3 2.2 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF3519 PF12033.8 EON98128.1 - 4.1 7.9 7.7 3.2 8.2 1.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) RPN7 PF10602.9 EON98131.1 - 1.1e-44 152.1 0.1 2.1e-44 151.3 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EON98131.1 - 1.9e-15 57.3 0.1 4.8e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 PCI domain XkdW PF09636.10 EON98131.1 - 0.11 12.6 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 XkdW protein TPR_16 PF13432.6 EON98131.1 - 0.13 13.0 2.7 18 6.1 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat eIF-6 PF01912.18 EON98132.1 - 7.3e-81 270.3 1.0 1.1e-80 269.7 1.0 1.2 1 0 0 1 1 1 1 eIF-6 family CBFD_NFYB_HMF PF00808.23 EON98133.1 - 6.4e-13 48.8 2.0 1e-12 48.2 2.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EON98133.1 - 0.0075 16.6 0.2 0.0075 16.6 0.2 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 EON98133.1 - 0.046 13.8 1.5 0.068 13.3 1.5 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region ANAPC4 PF12896.7 EON98134.1 - 1.1e-45 155.7 0.0 1.6e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Fungal_trans PF04082.18 EON98135.1 - 2.9e-20 72.4 0.0 5.6e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Myb_DNA-bind_7 PF15963.5 EON98136.1 - 2.4e-22 78.6 5.7 2.7e-22 78.4 1.2 2.5 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EON98136.1 - 6.1e-08 32.7 0.0 1.4e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EON98136.1 - 0.00053 20.2 0.1 0.0013 19.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EON98136.1 - 0.039 14.2 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 DHC PF09626.10 EON98136.1 - 0.069 14.0 0.2 0.2 12.6 0.1 1.8 2 0 0 2 2 2 0 Dihaem cytochrome c WAC_Acf1_DNA_bd PF10537.9 EON98137.1 - 2.8e-41 140.1 0.0 9.9e-41 138.4 0.0 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EON98137.1 - 2.7e-18 66.3 0.2 2.7e-18 66.3 0.2 3.4 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EON98137.1 - 2.7e-17 62.8 0.2 4.6e-17 62.1 0.2 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 EON98137.1 - 7.1e-10 38.2 0.2 4.1e-09 35.8 0.0 2.5 3 0 0 3 3 3 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF4407 PF14362.6 EON98137.1 - 3.6 6.9 17.3 6 6.1 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) adh_short_C2 PF13561.6 EON98138.1 - 2.1e-44 151.8 0.0 3.1e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON98138.1 - 4.3e-36 124.2 0.0 6.4e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase GST_N_3 PF13417.6 EON98138.1 - 2e-12 47.3 0.0 4.2e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EON98138.1 - 1.1e-11 44.8 0.0 2.6e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain KR PF08659.10 EON98138.1 - 1.3e-08 35.0 0.0 2.7e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 KR domain GST_N_2 PF13409.6 EON98138.1 - 2.8e-08 33.9 0.1 5.4e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EON98138.1 - 1.2e-06 28.8 0.0 2.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EON98138.1 - 7.4e-06 26.1 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EON98138.1 - 0.032 14.3 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EON98138.1 - 0.041 14.2 0.0 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein Epimerase PF01370.21 EON98138.1 - 0.052 13.0 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GST_N_4 PF17172.4 EON98138.1 - 0.17 12.7 0.0 0.55 11.0 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Aminotran_3 PF00202.21 EON98139.1 - 6.1e-52 176.6 0.0 7.4e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF3535 PF12054.8 EON98140.1 - 5.5e-133 444.4 2.5 1.2e-131 440.0 2.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EON98140.1 - 1.9e-67 227.4 0.0 4.9e-67 226.1 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EON98140.1 - 3.3e-19 69.3 0.0 9.3e-19 67.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 EON98140.1 - 2.9e-17 61.3 2.9 0.011 15.9 0.0 8.8 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 EON98140.1 - 1.2e-09 38.4 3.7 0.00026 21.3 0.0 6.9 7 0 0 7 7 7 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EON98140.1 - 2.6e-08 34.4 0.6 0.23 12.1 0.0 4.1 2 1 1 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EON98140.1 - 0.00012 22.5 8.1 6 7.5 0.0 8.0 10 0 0 10 10 10 2 HEAT-like repeat CLASP_N PF12348.8 EON98140.1 - 0.01 15.4 0.4 3.2 7.2 0.4 3.3 3 1 0 3 3 3 0 CLASP N terminal ERCC3_RAD25_C PF16203.5 EON98140.1 - 0.062 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Adaptin_N PF01602.20 EON98140.1 - 0.1 11.2 4.5 0.8 8.2 0.3 3.5 4 1 1 5 5 5 0 Adaptin N terminal region Anillin PF08174.11 EON98141.1 - 1.6e-15 57.8 0.2 6e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.29 EON98141.1 - 1.8e-08 34.8 0.0 6.5e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 PH domain Sulfotransfer_3 PF13469.6 EON98142.1 - 4.5e-06 27.2 0.0 4.1e-05 24.1 0.0 2.4 1 1 0 1 1 1 1 Sulfotransferase family SNF2_N PF00176.23 EON98143.1 - 8.6e-74 248.3 1.2 8.6e-74 248.3 1.2 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EON98143.1 - 7.3e-22 77.8 0.1 8.1e-19 68.0 0.0 3.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 EON98143.1 - 4e-21 74.9 0.2 1.4e-20 73.1 0.2 2.0 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 EON98143.1 - 1.4e-19 70.1 14.2 1.4e-19 70.1 14.2 5.6 6 0 0 6 6 6 1 HSA SnAC PF14619.6 EON98143.1 - 4.3e-14 52.9 0.4 4.3e-14 52.9 0.4 3.8 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 EON98143.1 - 5.5e-13 48.4 4.9 5.5e-13 48.4 4.9 2.6 2 0 0 2 2 2 1 QLQ ResIII PF04851.15 EON98143.1 - 1.3e-10 41.5 0.0 1.3e-10 41.5 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RBR PF17208.3 EON98143.1 - 0.13 12.9 8.7 0.14 12.9 6.2 2.5 1 1 0 1 1 1 0 RNA binding Region DUF4602 PF15375.6 EON98144.1 - 2.4e-08 34.4 10.3 8.5e-08 32.6 10.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) Myotub-related PF06602.14 EON98145.1 - 4.2e-150 499.5 0.0 5.2e-150 499.2 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EON98145.1 - 0.096 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF3543 PF12063.8 EON98146.1 - 1.8e-97 325.7 1.1 2.6e-97 325.2 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 EON98146.1 - 2.1e-38 132.2 0.0 3.7e-38 131.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON98146.1 - 8.9e-24 84.2 0.0 1.8e-23 83.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EON98146.1 - 0.079 12.9 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family ALMT PF11744.8 EON98147.1 - 5.9 5.6 10.6 0.042 12.7 2.0 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter Peptidase_C50 PF03568.17 EON98148.1 - 6e-170 565.6 0.0 7.2e-170 565.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 EON98148.1 - 8.7e-07 28.6 0.0 8e-05 22.2 0.0 2.2 1 1 0 1 1 1 1 CHAT domain STE PF02200.16 EON98149.1 - 2.2e-56 189.0 0.1 3.3e-56 188.4 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 EON98149.1 - 0.00057 20.2 3.0 0.56 10.8 0.4 2.7 1 1 1 2 2 2 2 Zinc finger, C2H2 type zf-C3HC4_3 PF13920.6 EON98150.1 - 0.0012 18.6 12.4 0.0018 18.1 12.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EON98150.1 - 0.067 13.1 6.2 0.11 12.4 6.2 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein ADH_N PF08240.12 EON98151.1 - 2.3e-17 62.9 1.5 7.8e-17 61.1 1.5 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON98151.1 - 9.4e-17 61.2 0.0 1.9e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EON98151.1 - 1.9e-06 27.5 0.0 3.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EON98151.1 - 0.0054 16.0 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_assoc PF13823.6 EON98151.1 - 0.0083 16.0 0.1 0.019 14.9 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 EON98151.1 - 0.035 15.2 0.0 0.081 14.0 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase EamA PF00892.20 EON98152.1 - 1.9e-10 41.1 25.2 4.1e-05 23.8 12.3 2.5 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EON98152.1 - 6.6e-09 35.4 0.1 1e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 EON98152.1 - 9.1e-05 21.9 0.9 9.1e-05 21.9 0.9 1.8 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.11 EON98152.1 - 0.0016 17.7 4.0 0.003 16.8 4.0 1.3 1 0 0 1 1 1 1 UAA transporter family DUF423 PF04241.15 EON98152.1 - 0.74 10.1 7.4 0.85 9.9 1.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF423) ABC_membrane PF00664.23 EON98153.1 - 2.3e-82 276.7 34.3 2.2e-45 155.5 6.6 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EON98153.1 - 3.6e-51 173.3 0.1 2e-29 102.9 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EON98153.1 - 2.9e-10 39.9 3.2 0.0033 16.9 0.1 4.1 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain MTABC_N PF16185.5 EON98153.1 - 4.2e-06 26.4 10.4 1.3e-05 24.9 10.4 1.8 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region MMR_HSR1 PF01926.23 EON98153.1 - 5.3e-06 26.5 0.1 0.11 12.6 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EON98153.1 - 8.2e-06 25.8 0.1 0.013 15.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EON98153.1 - 0.0004 20.8 0.4 0.03 14.7 0.2 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EON98153.1 - 0.00083 19.9 0.2 0.15 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EON98153.1 - 0.0014 18.4 1.3 0.12 12.1 0.0 3.1 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EON98153.1 - 0.0054 16.8 1.1 0.47 10.5 0.1 2.6 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 EON98153.1 - 0.0059 16.7 0.8 0.42 10.7 0.4 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_15 PF13175.6 EON98153.1 - 0.012 15.3 0.1 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 EON98153.1 - 0.018 14.8 0.2 4.6 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EON98153.1 - 0.035 14.4 0.8 21 5.4 0.2 3.3 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EON98153.1 - 0.05 14.0 0.0 12 6.4 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_29 PF13555.6 EON98153.1 - 0.055 13.2 5.0 3 7.7 0.0 3.0 3 0 0 3 3 2 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EON98153.1 - 0.063 13.0 0.5 2.9 7.6 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein NACHT PF05729.12 EON98153.1 - 0.085 12.8 2.0 0.24 11.3 0.1 2.6 3 0 0 3 3 3 0 NACHT domain FtsK_SpoIIIE PF01580.18 EON98153.1 - 0.12 11.7 0.1 12 5.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 EON98153.1 - 0.12 11.9 0.1 16 5.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 EON98153.1 - 0.13 11.3 0.4 0.75 8.8 0.2 2.1 2 1 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 EON98153.1 - 0.13 12.4 0.1 31 4.8 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase HLH PF00010.26 EON98154.1 - 3.1e-12 46.3 0.3 6.1e-12 45.3 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SAP130_C PF16014.5 EON98154.1 - 0.0034 16.5 3.2 0.004 16.3 3.2 1.1 1 0 0 1 1 1 1 Histone deacetylase complex subunit SAP130 C-terminus GIT1_C PF12205.8 EON98154.1 - 0.026 14.7 1.2 0.25 11.4 1.2 2.2 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF3450 PF11932.8 EON98154.1 - 0.043 13.1 0.4 0.043 13.1 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Pox_A30L_A26L PF06086.12 EON98154.1 - 0.19 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein Adeno_PIX PF03955.14 EON98154.1 - 0.79 9.9 8.4 0.38 10.9 5.6 1.9 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF2420 PF10336.9 EON98155.1 - 1.6e-06 28.1 0.0 2.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Methyltransf_31 PF13847.6 EON98156.1 - 2.2e-14 53.5 0.0 5.7e-14 52.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON98156.1 - 4.1e-09 37.0 0.0 1.6e-08 35.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON98156.1 - 5.8e-09 36.6 0.0 1.5e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON98156.1 - 4.7e-08 33.0 0.0 1.4e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON98156.1 - 3.1e-07 30.9 0.0 1.2e-06 29.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 EON98156.1 - 0.00012 22.4 0.0 0.00025 21.3 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MTS PF05175.14 EON98156.1 - 0.00046 19.8 0.0 0.00076 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EON98156.1 - 0.00078 19.5 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EON98156.1 - 0.023 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 EON98156.1 - 0.067 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EON98156.1 - 0.24 10.8 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Cation_efflux PF01545.21 EON98157.1 - 6.7e-50 169.6 4.3 1.3e-49 168.7 4.3 1.5 1 0 0 1 1 1 1 Cation efflux family FGGY_C PF02782.16 EON98157.1 - 2.8e-25 89.2 0.0 5.5e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Abhydrolase_3 PF07859.13 EON98157.1 - 2.2e-19 70.2 0.1 3.9e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EON98157.1 - 7.6e-17 61.2 0.0 1.2e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase FGGY_N PF00370.21 EON98157.1 - 4.5e-13 49.3 0.0 1.4e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain ZT_dimer PF16916.5 EON98157.1 - 0.00014 21.9 0.1 0.00028 21.0 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter COesterase PF00135.28 EON98157.1 - 0.11 11.3 0.6 0.55 9.0 0.6 1.9 1 1 0 1 1 1 0 Carboxylesterase family L31 PF09784.9 EON98158.1 - 1.1e-46 157.4 1.9 1.2e-46 157.3 1.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 JAKMIP_CC3 PF16034.5 EON98158.1 - 0.029 14.3 0.3 0.036 14.0 0.3 1.1 1 0 0 1 1 1 0 JAKMIP CC3 domain DUF3716 PF12511.8 EON98159.1 - 3.4e-05 23.8 0.0 5.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Filament PF00038.21 EON98160.1 - 0.0071 16.0 6.0 0.012 15.2 6.0 1.3 1 0 0 1 1 1 1 Intermediate filament protein MscS_porin PF12795.7 EON98160.1 - 0.029 13.9 7.1 0.046 13.3 7.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain TPD52 PF04201.15 EON98160.1 - 0.035 13.7 0.5 0.08 12.6 0.5 1.6 1 0 0 1 1 1 0 Tumour protein D52 family FAM76 PF16046.5 EON98160.1 - 0.35 10.2 1.5 0.71 9.2 1.5 1.4 1 0 0 1 1 1 0 FAM76 protein UPF0242 PF06785.11 EON98160.1 - 9.1 6.3 9.3 19 5.3 9.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus IBN_N PF03810.19 EON98161.1 - 2.5e-14 52.9 6.2 6.4e-13 48.4 0.1 4.0 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.10 EON98161.1 - 1.7e-09 37.0 0.0 4.7e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 EON98161.1 - 1.6e-05 25.0 5.9 4.1e-05 23.7 0.1 3.9 5 0 0 5 5 5 1 Exportin 1-like protein RIX1 PF08167.12 EON98161.1 - 0.0028 17.4 0.7 2.4 7.9 0.0 4.4 5 1 0 5 5 5 1 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 EON98161.1 - 0.038 14.6 0.7 5 7.8 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EON98161.1 - 0.22 11.5 1.9 0.36 10.9 0.1 2.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EON98161.1 - 1.5 9.3 4.4 1.4 9.3 0.1 3.3 3 0 0 3 3 3 0 HEAT repeat IMS PF00817.20 EON98162.1 - 5.3e-32 110.9 0.0 1.5e-31 109.4 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 EON98162.1 - 1.5e-09 38.5 0.0 3.8e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EON98162.1 - 0.0073 16.6 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif PMT PF02366.18 EON98163.1 - 4.3e-79 265.5 16.9 8.4e-79 264.6 16.9 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EON98163.1 - 1.3e-68 230.6 13.7 1.3e-68 230.6 13.7 2.4 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EON98163.1 - 2.5e-49 167.7 0.0 4.3e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 MIR domain Gamma-thionin PF00304.20 EON98164.1 - 4.4 7.7 8.7 7.6 6.9 8.3 1.6 1 1 0 1 1 1 0 Gamma-thionin family UCH PF00443.29 EON98165.1 - 9.7e-50 169.4 0.0 1.2e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EON98165.1 - 3.9e-13 48.9 0.2 3.2e-12 46.0 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin family UCH_1 PF13423.6 EON98165.1 - 3e-12 46.8 5.1 2.2e-10 40.7 5.1 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TBK1_ULD PF18396.1 EON98165.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain PNP_UDP_1 PF01048.20 EON98166.1 - 0.00064 19.1 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily PRP21_like_P PF12230.8 EON98167.1 - 3.8e-59 200.2 7.9 9e-59 199.0 7.9 1.6 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EON98167.1 - 8.5e-37 124.9 2.0 2.5e-18 65.8 0.1 2.9 3 0 0 3 3 3 2 Surp module Peptidase_S7 PF00949.21 EON98167.1 - 0.0037 17.1 0.0 0.0091 15.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease zf_UBZ PF18439.1 EON98167.1 - 0.0041 16.7 0.4 0.0074 15.9 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Trypsin_2 PF13365.6 EON98167.1 - 0.027 15.4 6.5 0.99 10.3 2.4 4.0 3 1 0 3 3 3 0 Trypsin-like peptidase domain TrmO_C PF18389.1 EON98167.1 - 0.03 14.4 0.0 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 TrmO C-terminal domain Peptidase_S3 PF00944.19 EON98167.1 - 0.11 12.3 0.3 0.24 11.2 0.1 1.6 2 0 0 2 2 2 0 Alphavirus core protein Mito_carr PF00153.27 EON98168.1 - 7.5e-72 237.3 2.4 3e-24 84.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EON98168.1 - 0.0014 18.8 0.0 1.5 9.1 0.0 3.4 4 0 0 4 4 4 1 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Serine_protease PF18405.1 EON98168.1 - 0.0029 16.8 3.8 0.051 12.7 0.2 2.9 1 1 2 4 4 4 2 Gammaproteobacterial serine protease ART PF01129.18 EON98168.1 - 0.046 13.0 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase LPD37 PF18853.1 EON98169.1 - 0.029 13.9 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 37 Sec2p PF06428.11 EON98170.1 - 1.2e-29 102.1 28.3 4.4e-29 100.3 21.6 2.5 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p T3SS_needle_F PF09392.10 EON98170.1 - 2.6 8.3 7.3 2.8 8.2 2.1 3.0 1 1 1 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Med9 PF07544.13 EON98170.1 - 4.1 7.6 18.3 0.27 11.3 0.5 3.1 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF3123 PF11321.8 EON98170.1 - 6.4 7.5 0.0 6.4 7.5 0.0 3.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3123) Methyltransf_23 PF13489.6 EON98171.1 - 1.1e-08 35.1 0.0 1.8e-08 34.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON98171.1 - 1.9e-05 25.3 0.5 0.00069 20.2 0.2 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON98171.1 - 0.00052 20.7 0.2 1.1 10.0 0.0 2.7 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EON98171.1 - 0.0015 18.3 0.0 1.7 8.5 0.1 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EON98171.1 - 0.0063 17.2 0.1 0.099 13.4 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON98171.1 - 0.0079 15.5 0.0 0.35 10.2 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Oxidored_FMN PF00724.20 EON98171.1 - 0.014 14.7 0.1 0.019 14.2 0.1 1.1 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family adh_short PF00106.25 EON98172.1 - 5.1e-33 114.2 4.2 7.9e-33 113.6 4.2 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON98172.1 - 1.3e-27 96.9 7.9 3.7e-27 95.4 7.9 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON98172.1 - 1.1e-10 41.7 1.9 7.5e-10 39.0 1.9 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EON98172.1 - 0.0018 17.8 0.4 0.0021 17.6 0.4 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EON98172.1 - 0.0034 16.6 0.1 0.0045 16.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein LAP2alpha PF11560.8 EON98172.1 - 0.047 13.1 1.5 0.056 12.9 1.0 1.4 1 1 0 1 1 1 0 Lamina-associated polypeptide 2 alpha Pectate_lyase_3 PF12708.7 EON98175.1 - 5.4e-28 98.3 13.9 9.6e-16 58.3 0.5 4.7 4 1 1 5 5 5 3 Pectate lyase superfamily protein End_N_terminal PF12218.8 EON98175.1 - 0.011 15.4 0.1 0.042 13.6 0.1 2.1 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase ARPC4 PF05856.12 EON98177.1 - 5.7e-75 250.5 3.3 6.8e-75 250.3 3.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) AAA_16 PF13191.6 EON98178.1 - 0.00033 21.1 0.0 0.48 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 EON98178.1 - 0.00075 19.7 0.1 0.0074 16.4 0.1 2.1 1 1 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 EON98178.1 - 0.0035 17.6 0.0 0.71 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EON98178.1 - 0.012 14.9 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.18 EON98178.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF853 PF05872.12 EON98178.1 - 0.065 11.8 0.0 0.2 10.2 0.0 1.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) BSD PF03909.17 EON98180.1 - 0.0044 17.0 24.4 0.67 10.0 0.2 5.8 2 2 5 7 7 7 4 BSD domain Baculo_PEP_C PF04513.12 EON98180.1 - 0.076 13.1 8.6 1.9 8.5 1.1 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FPRL1_inhibitor PF16104.5 EON98180.1 - 3.7 7.7 12.4 9.5 6.4 0.5 3.6 1 1 4 5 5 5 0 Formyl peptide receptor-like 1 inhibitory protein Pkinase PF00069.25 EON98182.1 - 1.9e-51 175.0 0.0 2.7e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON98182.1 - 3.5e-26 92.0 0.1 2.2e-24 86.2 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EON98182.1 - 0.0013 17.6 0.0 0.0013 17.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 EON98182.1 - 0.015 14.9 0.7 1.8 8.1 0.1 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EON98182.1 - 0.037 13.3 0.1 0.068 12.5 0.1 1.3 1 0 0 1 1 1 0 Kinase-like His_Phos_1 PF00300.22 EON98183.1 - 9.4e-34 116.8 0.5 3.6e-18 66.0 0.2 2.2 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Peptidase_S7 PF00949.21 EON98184.1 - 0.0019 18.0 0.1 0.0037 17.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Trypsin_2 PF13365.6 EON98184.1 - 0.021 15.7 0.0 0.76 10.7 0.0 2.3 2 0 0 2 2 2 0 Trypsin-like peptidase domain DUF31 PF01732.16 EON98184.1 - 0.034 13.7 0.1 0.06 12.9 0.1 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S32 PF05579.13 EON98184.1 - 0.15 11.2 0.0 0.44 9.7 0.0 1.7 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 PX PF00787.24 EON98185.1 - 2.7e-25 88.5 0.0 3.1e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 PX domain CBM_20 PF00686.19 EON98186.1 - 3.7e-17 62.0 0.2 6.8e-17 61.2 0.2 1.4 1 0 0 1 1 1 1 Starch binding domain Response_reg PF00072.24 EON98187.1 - 2.4e-20 72.8 0.0 2.6e-14 53.3 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain DUF2000 PF09391.10 EON98187.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) JAB PF01398.21 EON98190.1 - 4.9e-05 23.3 0.2 0.0013 18.7 0.2 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Imm68 PF15583.6 EON98191.1 - 0.071 13.3 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 Immunity protein 68 Mito_carr PF00153.27 EON98192.1 - 7.9e-45 150.7 8.9 1.3e-18 66.7 0.5 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EON98192.1 - 0.047 12.8 3.0 0.5 9.5 0.3 2.2 2 0 0 2 2 2 0 Gammaproteobacterial serine protease 2-Hacid_dh_C PF02826.19 EON98193.1 - 7.4e-55 185.1 0.0 1.1e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EON98193.1 - 1.1e-21 76.9 0.0 1.4e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EON98193.1 - 3.4e-05 24.1 0.0 5.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase PF05221.17 EON98194.1 - 3.2e-131 436.9 0.0 2.1e-74 250.3 0.2 2.1 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EON98194.1 - 1.1e-82 275.9 3.4 1.9e-82 275.1 3.4 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EON98194.1 - 6e-06 25.7 0.2 1.2e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 EON98194.1 - 0.032 14.0 0.5 0.075 12.7 0.4 1.7 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.12 EON98194.1 - 0.039 13.5 0.4 0.072 12.7 0.4 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EON98194.1 - 0.092 13.0 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain RNA_Me_trans PF04252.13 EON98195.1 - 1.2e-49 168.6 0.1 1.1e-27 97.0 0.0 2.0 1 1 1 2 2 2 2 Predicted SAM-dependent RNA methyltransferase MARVEL PF01284.23 EON98196.1 - 3.1e-19 69.4 13.9 3.7e-19 69.2 13.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain 7TM_GPCR_Srx PF10328.9 EON98196.1 - 0.0038 16.9 1.0 0.0047 16.6 1.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx ABC2_membrane_5 PF13346.6 EON98196.1 - 0.053 13.1 4.5 0.063 12.8 4.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Pox_A14 PF05767.12 EON98196.1 - 0.076 13.2 0.1 0.17 12.0 0.1 1.7 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 MRC1 PF09444.10 EON98197.1 - 7.9e-44 149.7 20.0 7.9e-44 149.7 20.0 8.3 7 2 1 9 9 9 1 MRC1-like domain APG5 PF04106.12 EON98198.1 - 3.4e-43 147.9 0.0 6.1e-43 147.0 0.0 1.5 1 1 0 1 1 1 1 Autophagy protein Apg5 GCP_C_terminal PF04130.13 EON98199.1 - 2e-99 332.9 0.0 3.2e-99 332.3 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EON98199.1 - 5.9e-84 282.3 0.0 1.8e-83 280.7 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal APG17 PF04108.12 EON98199.1 - 0.065 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF3921 PF13060.6 EON98199.1 - 0.17 12.0 0.0 0.44 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) SAGA-Tad1 PF12767.7 EON98200.1 - 7.9e-40 137.1 0.0 9.6e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit RGS PF00615.19 EON98202.1 - 0.0013 19.0 0.0 0.014 15.6 0.0 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain MFS_Mycoplasma PF07672.13 EON98202.1 - 0.0024 17.2 2.3 0.0024 17.2 2.3 1.5 2 0 0 2 2 2 1 Mycoplasma MFS transporter UNC-93 PF05978.16 EON98202.1 - 2.2 8.0 5.8 0.28 10.9 0.2 2.2 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 DHO_dh PF01180.21 EON98203.1 - 6.4e-20 71.5 0.0 9.5e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PUL PF08324.11 EON98204.1 - 7.8e-75 251.7 0.3 1.2e-74 251.0 0.3 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EON98204.1 - 1.7e-44 150.7 0.3 2.9e-44 149.9 0.3 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EON98204.1 - 1.8e-30 104.5 9.4 3.3e-06 27.7 0.0 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_3 PF13570.6 EON98204.1 - 0.011 16.2 0.8 0.27 11.8 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain ANAPC4_WD40 PF12894.7 EON98204.1 - 0.018 15.3 0.2 16 5.9 0.0 4.1 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EON98204.1 - 0.018 15.1 0.0 2.1 8.4 0.0 3.2 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 EON98204.1 - 0.033 12.9 0.1 4.1 6.0 0.0 2.4 1 1 0 2 2 2 0 Nup133 N terminal like WD40_like PF17005.5 EON98204.1 - 0.078 12.3 0.0 0.22 10.8 0.0 1.8 1 0 0 1 1 1 0 WD40-like domain HLH PF00010.26 EON98205.1 - 3.8e-17 62.0 0.0 6.6e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.21 EON98205.1 - 0.019 15.0 0.2 0.17 12.0 0.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor TSC22 PF01166.18 EON98205.1 - 0.066 13.5 0.2 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family ZapB PF06005.12 EON98205.1 - 0.081 13.4 0.0 11 6.6 0.1 2.5 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_2 PF07716.15 EON98205.1 - 0.46 10.6 0.1 0.46 10.6 0.1 2.7 3 0 0 3 3 3 0 Basic region leucine zipper DUF5521 PF17659.1 EON98205.1 - 0.7 7.7 2.1 0.9 7.3 2.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) DUF4692 PF15763.5 EON98205.1 - 0.77 10.2 7.2 1.5 9.3 7.2 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) WD40 PF00400.32 EON98206.1 - 8.8e-19 67.5 6.8 1.6e-07 31.9 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON98206.1 - 0.00067 19.9 0.0 0.21 11.9 0.0 3.8 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EON98206.1 - 0.002 17.1 0.0 0.097 11.6 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Amidase PF01425.21 EON98207.1 - 2.5e-28 99.2 0.1 3.7e-28 98.7 0.1 1.2 1 0 0 1 1 1 1 Amidase HNH_4 PF13395.6 EON98207.1 - 0.066 13.1 0.3 4.6 7.2 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease DUF1524 PF07510.11 EON98207.1 - 0.079 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) VIT PF08487.10 EON98208.1 - 1e-34 119.1 0.2 1.3e-33 115.5 0.0 2.6 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EON98208.1 - 3.7e-26 91.9 0.0 8.7e-26 90.7 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 EON98208.1 - 1.1e-12 47.6 0.1 2.2e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 EON98208.1 - 3.7e-11 43.6 0.0 6.4e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EON98208.1 - 7.5e-10 39.4 0.0 2e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EON98208.1 - 0.044 13.2 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Mtr2 PF10429.9 EON98209.1 - 0.0089 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 ATG16 PF08614.11 EON98210.1 - 0.0001 22.6 0.0 0.0004 20.7 0.0 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 EON98210.1 - 0.0026 17.8 0.1 0.55 10.3 0.0 2.1 1 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 EON98210.1 - 0.0039 17.6 2.8 0.43 11.1 2.8 2.4 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 EON98210.1 - 0.013 15.5 0.7 0.013 15.5 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 EON98210.1 - 0.015 15.3 0.4 0.015 15.3 0.4 1.7 2 0 0 2 2 2 0 Laminin Domain II DUF948 PF06103.11 EON98210.1 - 0.037 14.3 1.3 0.073 13.3 1.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) LemA PF04011.12 EON98210.1 - 0.06 13.2 2.6 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 LemA family DUF2730 PF10805.8 EON98210.1 - 0.094 12.8 0.1 5.8 7.1 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) Focal_AT PF03623.13 EON98210.1 - 0.3 11.1 5.3 1.4 8.9 0.1 2.2 2 0 0 2 2 2 0 Focal adhesion targeting region FAM25 PF15825.5 EON98210.1 - 1.5 9.3 6.2 0.25 11.7 1.2 2.1 2 1 0 2 2 2 0 FAM25 family Abhydrolase_6 PF12697.7 EON98211.1 - 3.5e-12 47.4 0.4 4.2e-12 47.1 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family OPT PF03169.15 EON98212.1 - 0.00017 20.4 0.2 0.00021 20.1 0.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FlgM PF04316.13 EON98212.1 - 0.049 14.0 0.0 0.14 12.5 0.0 1.8 1 1 0 1 1 1 0 Anti-sigma-28 factor, FlgM RRM_Rrp7 PF17799.1 EON98212.1 - 0.11 12.4 0.3 0.14 11.9 0.3 1.2 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain zinc_ribbon_10 PF10058.9 EON98213.1 - 1.1e-18 66.7 0.1 2e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein CCDC-167 PF15188.6 EON98213.1 - 0.0095 16.3 0.1 0.031 14.6 0.0 1.8 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 167 DUF3611 PF12263.8 EON98213.1 - 0.061 13.2 0.2 0.092 12.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) zf-RanBP PF00641.18 EON98213.1 - 0.16 11.3 2.4 0.16 11.3 0.2 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others SlyX PF04102.12 EON98213.1 - 0.28 11.8 0.7 1.1 10.0 0.0 2.2 2 0 0 2 2 2 0 SlyX WD40 PF00400.32 EON98214.1 - 3.7e-11 43.4 4.2 0.35 11.8 0.0 6.9 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON98214.1 - 0.037 14.3 0.0 30 5.0 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIF_alpha PF05793.12 EON98214.1 - 0.52 8.8 22.9 0.87 8.1 22.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 EON98214.1 - 4.6 5.4 12.6 5.8 5.1 12.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Sugar_tr PF00083.24 EON98216.1 - 1.2e-11 44.2 5.5 1.3e-11 44.0 5.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON98216.1 - 5.4e-07 28.9 12.1 6.8e-07 28.5 12.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ADH_zinc_N_2 PF13602.6 EON98217.1 - 2.3e-29 103.1 0.0 5.1e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EON98217.1 - 5.2e-16 58.8 0.1 1.2e-15 57.7 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON98217.1 - 2.8e-06 27.2 0.2 0.00046 20.0 0.0 2.6 1 1 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain SRR1 PF07985.12 EON98218.1 - 2.5e-10 40.2 0.5 4.7e-09 36.2 0.5 2.5 1 1 0 1 1 1 1 SRR1 Lipase_GDSL_2 PF13472.6 EON98220.1 - 2.4e-13 50.9 1.7 5.4e-13 49.7 1.7 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family VCBS PF13517.6 EON98220.1 - 4.8e-13 49.5 22.7 3.2e-10 40.5 4.8 5.2 3 1 1 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Aerolysin PF01117.20 EON98220.1 - 0.00043 19.6 0.0 0.00094 18.5 0.0 1.5 1 0 0 1 1 1 1 Aerolysin toxin Ntox34 PF15606.6 EON98220.1 - 0.0031 17.6 0.4 0.059 13.5 0.1 2.6 2 0 0 2 2 2 1 Bacterial toxin 34 Lipase_GDSL PF00657.22 EON98220.1 - 0.0051 16.8 0.1 0.014 15.4 0.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF1522 PF07482.11 EON98220.1 - 0.61 10.4 5.5 0.25 11.7 0.4 3.0 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1522) AAA_12 PF13087.6 EON98222.1 - 1.2e-36 126.2 0.0 2.6e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EON98222.1 - 1.1e-25 90.9 0.0 3.3e-25 89.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON98222.1 - 1.5e-09 37.8 0.2 1.8e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EON98222.1 - 3.9e-09 37.0 0.0 4.3e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EON98222.1 - 0.00086 19.1 0.0 0.32 10.7 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EON98222.1 - 0.0039 16.7 0.0 0.0083 15.6 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.15 EON98222.1 - 0.04 13.9 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Rav1p_C PF12234.8 EON98222.1 - 0.084 11.3 0.1 0.12 10.7 0.1 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal UvrD-helicase PF00580.21 EON98222.1 - 0.11 12.0 1.8 0.29 10.6 0.2 2.5 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 EON98222.1 - 0.11 11.7 0.1 0.27 10.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF1993 PF09351.10 EON98224.1 - 5.8e-52 176.1 0.0 6.4e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) MFS_1 PF07690.16 EON98225.1 - 3.1e-30 105.3 25.3 3.1e-30 105.3 25.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EON98225.1 - 9.8e-09 35.0 4.3 9.8e-09 35.0 4.3 2.2 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB 2TM PF13239.6 EON98225.1 - 0.23 11.8 0.1 0.23 11.8 0.1 4.2 3 2 1 4 4 4 0 2TM domain zf-RING_2 PF13639.6 EON98227.1 - 1.6e-08 34.7 4.6 1.6e-08 34.7 4.6 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EON98227.1 - 0.00016 21.6 1.7 0.00058 19.8 1.7 2.1 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_1 PF14446.6 EON98227.1 - 0.00031 20.6 4.6 0.005 16.7 1.6 2.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 EON98227.1 - 0.00087 19.0 5.3 0.003 17.3 5.3 2.0 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 EON98227.1 - 0.0012 19.0 3.8 0.0012 19.0 3.8 2.2 2 0 0 2 2 2 1 FANCL C-terminal domain PHD PF00628.29 EON98227.1 - 0.0021 17.9 5.1 0.0046 16.8 5.1 1.6 1 0 0 1 1 1 1 PHD-finger zf-ANAPC11 PF12861.7 EON98227.1 - 0.01 15.8 1.7 0.01 15.8 1.7 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EON98227.1 - 0.017 15.1 4.7 0.017 15.1 4.7 2.8 3 0 0 3 3 3 0 zinc-RING finger domain RINGv PF12906.7 EON98227.1 - 0.052 13.7 6.6 0.13 12.4 6.6 1.7 1 0 0 1 1 1 0 RING-variant domain zf-rbx1 PF12678.7 EON98227.1 - 1.7 9.0 11.3 0.14 12.4 4.5 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain GRIP PF01465.20 EON98228.1 - 1.6e-15 56.7 0.1 3.5e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 GRIP domain GAS PF13851.6 EON98228.1 - 0.00035 20.0 143.2 0.055 12.8 11.3 9.2 3 2 7 10 10 10 5 Growth-arrest specific micro-tubule binding DUF812 PF05667.11 EON98228.1 - 0.00058 18.9 29.0 0.00058 18.9 29.0 5.2 1 1 4 5 5 5 3 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 EON98228.1 - 0.00077 19.5 158.9 0.013 15.5 17.9 9.7 3 2 6 9 9 8 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 EON98228.1 - 0.00078 18.9 12.9 0.00078 18.9 12.9 6.9 1 1 5 6 6 5 2 Domain of unknown function (DUF4407) DUF4201 PF13870.6 EON98228.1 - 0.0014 18.4 0.2 0.0014 18.4 0.2 9.6 3 2 6 9 9 9 3 Domain of unknown function (DUF4201) MscS_porin PF12795.7 EON98228.1 - 0.0014 18.2 0.3 0.0014 18.2 0.3 8.0 3 2 3 6 6 5 2 Mechanosensitive ion channel porin domain TolA_bind_tri PF16331.5 EON98228.1 - 0.0026 17.8 13.0 0.0077 16.3 6.8 10.7 5 4 5 10 10 10 3 TolA binding protein trimerisation TMF_DNA_bd PF12329.8 EON98228.1 - 0.0031 17.5 6.8 0.0031 17.5 6.8 14.1 4 2 10 14 14 13 2 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 EON98228.1 - 0.0051 16.9 21.3 0.0051 16.9 21.3 10.0 3 2 5 9 9 9 4 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 EON98228.1 - 0.009 16.1 14.2 0.009 16.1 14.2 9.4 3 2 7 10 10 10 4 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 EON98228.1 - 0.021 14.6 0.6 0.021 14.6 0.6 14.8 7 4 10 18 18 18 0 Septum formation initiator Fez1 PF06818.15 EON98228.1 - 0.036 14.5 146.6 0.27 11.7 2.4 8.2 3 2 6 9 9 9 0 Fez1 APG6_N PF17675.1 EON98228.1 - 0.037 14.6 184.3 0.7 10.4 19.3 10.8 3 2 8 11 11 10 0 Apg6 coiled-coil region Spc7 PF08317.11 EON98228.1 - 0.21 10.5 153.6 0.014 14.3 20.4 8.5 3 2 5 8 8 8 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 EON98228.1 - 0.54 10.1 122.5 0.041 13.7 6.7 10.3 3 2 6 10 10 9 0 Phage minor structural protein GP20 Filament PF00038.21 EON98228.1 - 0.92 9.0 138.2 0.73 9.4 2.0 8.9 3 2 4 7 7 7 0 Intermediate filament protein Glyco_hydro_17 PF00332.18 EON98229.1 - 1.3e-12 47.9 2.7 1.4e-07 31.5 0.2 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF2140 PF09911.9 EON98229.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) Cellulase PF00150.18 EON98230.1 - 3.9e-53 180.7 1.4 4.9e-53 180.4 1.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 EON98230.1 - 1.7e-13 50.3 17.9 1.7e-13 50.3 17.9 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain DUF1479 PF07350.12 EON98231.1 - 7.9e-148 492.6 0.0 9.7e-148 492.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) TPP_enzyme_C PF02775.21 EON98234.1 - 2.8e-21 75.9 0.0 4.3e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EON98234.1 - 1.3e-12 47.6 0.0 6.3e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 EON98234.1 - 6.3e-12 45.4 0.0 1.9e-10 40.6 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Glyco_hyd_65N_2 PF14498.6 EON98236.1 - 3.1e-25 89.4 0.1 4e-18 66.2 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65, N-terminal domain VCBS PF13517.6 EON98237.1 - 1.1e-19 70.7 41.4 4.6e-10 39.9 3.2 6.9 3 2 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella NUT PF12881.7 EON98237.1 - 0.17 10.3 3.7 0.23 9.8 3.7 1.1 1 0 0 1 1 1 0 NUT protein TcdB_toxin_midN PF12256.8 EON98237.1 - 1.1 8.6 13.5 0.83 9.0 0.0 5.0 3 2 2 5 5 5 0 Insecticide toxin TcdB middle/N-terminal region RIO1 PF01163.22 EON98238.1 - 1.1e-68 230.6 1.0 1.4e-68 230.2 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 EON98238.1 - 0.01 14.6 0.3 0.01 14.6 0.3 1.8 2 0 0 2 2 2 0 Fungal protein kinase Glyco_hydro_1 PF00232.18 EON98239.1 - 2.5e-138 461.3 3.3 3.1e-138 461.0 3.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 VIT1 PF01988.19 EON98240.1 - 1e-64 218.4 0.3 1e-64 218.4 0.3 1.6 2 0 0 2 2 2 1 VIT family Beta-lactamase PF00144.24 EON98241.1 - 8.9e-49 166.5 0.1 1.2e-48 166.1 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Microvir_J PF04726.13 EON98241.1 - 0.31 11.1 0.5 0.77 9.8 0.2 1.7 2 0 0 2 2 2 0 Microvirus J protein p450 PF00067.22 EON98242.1 - 0.00026 19.9 0.0 0.00028 19.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AATase PF07247.12 EON98243.1 - 0.12 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Alcohol acetyltransferase Pro-kuma_activ PF09286.11 EON98244.1 - 2.2e-22 79.9 0.1 4.5e-22 78.9 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EON98244.1 - 0.001 18.4 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Goodbye PF17109.5 EON98245.1 - 8.4e-15 55.3 0.0 3.9e-14 53.1 0.0 2.3 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 EON98245.1 - 0.00027 20.9 0.3 0.0015 18.5 0.0 2.5 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 EON98245.1 - 0.0004 20.7 0.4 0.05 13.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EON98245.1 - 0.0012 19.3 0.9 0.016 15.6 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 EON98245.1 - 0.0019 18.5 0.0 0.006 17.0 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Dioxygenase_N PF04444.14 EON98245.1 - 0.0021 17.9 0.7 0.023 14.6 0.3 2.4 2 0 0 2 2 2 1 Catechol dioxygenase N terminus NTPase_1 PF03266.15 EON98245.1 - 0.043 13.7 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 NTPase TPR_2 PF07719.17 EON98245.1 - 0.047 13.8 3.3 64 4.0 0.1 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.10 EON98245.1 - 0.095 13.1 4.3 0.26 11.7 4.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AAA_19 PF13245.6 EON98245.1 - 0.12 12.7 0.0 0.83 10.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain HR1 PF02185.16 EON98245.1 - 0.31 11.2 3.9 0.55 10.4 0.3 3.2 3 0 0 3 3 3 0 Hr1 repeat DUF4215 PF13948.6 EON98246.1 - 0.0058 17.0 2.5 0.0087 16.5 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4215) Plasmodium_Vir PF05795.11 EON98246.1 - 0.44 9.9 1.4 0.52 9.7 1.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Hamartin PF04388.12 EON98246.1 - 0.79 8.3 9.0 0.91 8.1 9.0 1.0 1 0 0 1 1 1 0 Hamartin protein CBM_21 PF03370.13 EON98248.1 - 7.7e-36 122.7 0.3 1.2e-35 122.1 0.3 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EON98248.1 - 2.2e-12 47.4 0.8 4.1e-12 46.5 0.8 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Tyrosinase PF00264.20 EON98249.1 - 1.1e-54 186.1 1.7 1.4e-54 185.7 1.7 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase APG17 PF04108.12 EON98250.1 - 3.9e-139 464.2 5.3 4.4e-139 464.0 5.3 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Med30 PF11315.8 EON98250.1 - 0.03 14.5 2.2 0.34 11.1 0.2 3.1 4 0 0 4 4 4 0 Mediator complex subunit 30 EzrA PF06160.12 EON98250.1 - 0.099 10.8 6.0 0.16 10.1 2.7 2.4 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA DUF4358 PF14270.6 EON98250.1 - 0.12 12.6 1.8 0.19 12.0 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Syntaxin-6_N PF09177.11 EON98250.1 - 0.15 12.6 2.8 6.9 7.3 0.2 3.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Prominin PF05478.11 EON98250.1 - 0.22 9.4 1.5 7.4 4.4 0.3 2.1 2 0 0 2 2 2 0 Prominin P_C10 PF14974.6 EON98250.1 - 0.24 11.5 1.3 1.2 9.3 0.0 2.6 3 0 0 3 3 3 0 Protein C10 DUF4795 PF16043.5 EON98250.1 - 0.44 10.1 7.1 0.11 12.1 0.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) FlgN PF05130.12 EON98250.1 - 0.55 10.7 2.6 26 5.3 0.0 3.1 2 2 1 3 3 3 0 FlgN protein DASH_Duo1 PF08651.10 EON98250.1 - 0.56 10.0 2.3 64 3.4 0.1 3.6 4 0 0 4 4 4 0 DASH complex subunit Duo1 V_ATPase_I PF01496.19 EON98250.1 - 1.4 6.7 5.2 3.2 5.6 1.4 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 EON98250.1 - 1.6 8.8 6.0 8.9 6.4 0.2 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Peptidase_M24 PF00557.24 EON98251.1 - 3.1e-57 193.7 0.0 4.3e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EON98251.1 - 2.7e-24 85.2 0.0 5.3e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HET PF06985.11 EON98253.1 - 0.014 15.8 2.3 0.092 13.1 2.5 2.1 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) TIR_2 PF13676.6 EON98253.1 - 0.036 14.7 0.0 0.067 13.8 0.0 1.4 1 0 0 1 1 1 0 TIR domain Peptidase_M48_N PF16491.5 EON98253.1 - 1.1 9.2 5.1 1.9 8.4 5.1 1.3 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices Catalase PF00199.19 EON98254.1 - 1.2e-169 564.4 0.2 1.6e-169 564.1 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EON98254.1 - 1.8e-18 66.5 0.1 4.2e-18 65.3 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.24 EON98254.1 - 6.6e-09 35.8 0.0 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 EON98254.1 - 8.5e-09 35.2 0.3 2e-08 34.0 0.3 1.7 1 1 0 1 1 1 1 C-terminal domain found in long catalases AA_permease PF00324.21 EON98255.1 - 2.3e-110 369.5 39.8 2.9e-110 369.1 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON98255.1 - 1.2e-32 113.3 44.4 1.6e-32 112.9 44.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4231 PF14015.6 EON98255.1 - 0.51 10.8 4.2 4.5 7.8 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Peptidase_M14 PF00246.24 EON98256.1 - 2.8e-85 286.6 0.2 3.3e-85 286.4 0.2 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase MFS_1 PF07690.16 EON98258.1 - 2.3e-44 151.8 40.4 2.3e-44 151.8 40.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EON98258.1 - 1.6e-15 56.6 10.3 1.6e-15 56.6 10.3 1.7 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) EpuA PF11772.8 EON98258.1 - 0.82 9.4 0.0 0.82 9.4 0.0 3.2 3 0 0 3 3 3 0 DNA-directed RNA polymerase subunit beta Phage_holin_2_4 PF16082.5 EON98259.1 - 0.0087 15.8 4.9 0.016 14.9 4.9 1.4 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like TraL PF07178.11 EON98259.1 - 0.028 14.9 0.1 0.052 14.0 0.1 1.4 1 0 0 1 1 1 0 TraL protein Amnionless PF14828.6 EON98259.1 - 0.092 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless TraT PF05818.12 EON98259.1 - 1.5 8.4 6.6 2.6 7.7 6.6 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein GMC_oxred_N PF00732.19 EON98260.1 - 7.6e-58 196.2 0.0 9.7e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EON98260.1 - 1.2e-28 100.5 0.0 4.1e-28 98.7 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EON98260.1 - 2.3e-06 27.0 0.1 0.0011 18.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EON98260.1 - 4.4e-06 26.0 0.4 8.1e-06 25.1 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EON98260.1 - 0.00022 21.4 0.1 0.00081 19.6 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EON98260.1 - 0.00025 20.3 0.8 0.00051 19.4 0.1 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EON98260.1 - 0.0014 17.4 0.6 0.025 13.3 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EON98260.1 - 0.0015 18.2 0.2 0.0087 15.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON98260.1 - 0.0016 17.7 0.1 0.011 15.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON98260.1 - 0.0046 16.2 2.6 0.13 11.5 0.5 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EON98260.1 - 0.04 13.2 0.0 0.088 12.0 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 EON98260.1 - 0.045 14.0 0.1 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain DUF4097 PF13349.6 EON98260.1 - 0.077 12.3 0.0 0.16 11.2 0.0 1.6 1 1 0 1 1 1 0 Putative adhesin Cyclin PF08613.11 EON98261.1 - 3.1e-44 151.2 0.0 4.4e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin XFP_N PF09364.10 EON98263.1 - 2.7e-120 401.5 0.0 3.6e-120 401.1 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 EON98263.1 - 1.1e-77 260.1 0.0 2e-77 259.2 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 EON98263.1 - 6.9e-77 257.1 0.0 1.1e-76 256.5 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 EON98263.1 - 0.0004 20.2 0.3 0.0037 17.1 0.1 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.20 EON98263.1 - 0.085 12.7 0.2 1.7 8.5 0.2 2.4 1 1 1 2 2 2 0 Transketolase, C-terminal domain Amidase PF01425.21 EON98264.1 - 3.9e-39 134.9 0.1 3e-15 56.2 0.0 3.1 1 1 2 3 3 3 3 Amidase Ank_2 PF12796.7 EON98265.1 - 2.1e-21 76.3 0.5 8.9e-07 29.4 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EON98265.1 - 7.1e-14 51.5 1.0 0.003 17.9 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EON98265.1 - 1.2e-13 49.9 0.3 0.011 16.2 0.0 5.4 4 1 1 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EON98265.1 - 1.7e-13 50.8 1.0 7.4e-05 23.2 0.1 4.5 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EON98265.1 - 3.7e-07 30.3 0.2 0.0066 16.7 0.0 4.0 2 1 1 4 4 4 2 Ankyrin repeats (many copies) DUF924 PF06041.11 EON98266.1 - 4.4e-56 189.9 0.0 5.3e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) SnoaL_2 PF12680.7 EON98267.1 - 0.0021 18.7 0.0 0.0028 18.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain UDPGT PF00201.18 EON98269.1 - 1.8e-14 53.4 0.0 2.7e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Cation_ATPase_C PF00689.21 EON98270.1 - 3.3e-48 163.8 8.9 3.3e-48 163.8 8.9 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EON98270.1 - 1.8e-35 122.1 0.3 1.8e-35 122.1 0.3 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EON98270.1 - 3.8e-22 79.6 0.8 1e-21 78.2 0.8 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EON98270.1 - 1.1e-19 70.3 0.0 2.3e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EON98270.1 - 9.8e-12 44.4 0.1 7.6e-10 38.3 0.0 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EON98270.1 - 0.00014 21.7 0.3 0.00085 19.1 0.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EON98270.1 - 0.18 12.2 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FAD_binding_4 PF01565.23 EON98271.1 - 1.5e-20 73.3 1.8 3.2e-20 72.3 1.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EON98271.1 - 3.3e-12 46.3 0.1 5.3e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Berberine and berberine like Pectate_lyase PF03211.13 EON98272.1 - 2.7e-87 291.6 11.4 3e-87 291.4 11.4 1.0 1 0 0 1 1 1 1 Pectate lyase HATPase_c PF02518.26 EON98273.1 - 3.9e-20 72.4 0.0 7.4e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EON98273.1 - 3.9e-16 59.2 0.0 1.1e-15 57.8 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EON98273.1 - 3.8e-11 42.9 0.4 3.8e-11 42.9 0.4 2.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 EON98273.1 - 0.00043 20.9 0.0 0.0027 18.3 0.0 2.4 3 0 0 3 3 3 1 GAF domain GAF_2 PF13185.6 EON98273.1 - 0.0022 18.3 0.0 0.0073 16.6 0.0 2.0 1 0 0 1 1 1 1 GAF domain DUF2325 PF10087.9 EON98273.1 - 0.061 13.4 0.3 0.12 12.5 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Ferritin_2 PF13668.6 EON98274.1 - 1.7e-14 54.1 0.0 8.4e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 Ferritin-like domain SET PF00856.28 EON98275.1 - 4.2e-10 40.3 0.0 7.6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 SET domain adh_short PF00106.25 EON98276.1 - 1.7e-12 47.3 0.2 7.1e-12 45.2 0.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON98276.1 - 1.5e-11 44.4 1.0 5e-11 42.6 1.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Lon_C PF05362.13 EON98276.1 - 0.08 12.5 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Lon protease (S16) C-terminal proteolytic domain PUD1_2 PF18457.1 EON98276.1 - 0.16 11.9 0.1 0.23 11.4 0.1 1.2 1 0 0 1 1 1 0 Up-Regulated in long-lived daf-2 Transp_cyt_pur PF02133.15 EON98277.1 - 6e-114 381.2 36.8 6.9e-114 381.0 36.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Hydantoinase_B PF02538.14 EON98278.1 - 6.1e-42 143.7 7.5 6.6e-42 143.6 7.5 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Methyltransf_25 PF13649.6 EON98279.1 - 4.9e-11 43.2 0.0 7e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON98279.1 - 2.4e-09 37.7 0.0 3.4e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON98279.1 - 4.4e-07 30.6 0.0 6.7e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON98279.1 - 1.2e-05 24.8 0.0 1.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EON98279.1 - 4.1e-05 23.4 0.0 5.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON98279.1 - 0.00011 22.1 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EON98279.1 - 0.0043 16.6 0.0 0.0083 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 EON98279.1 - 0.014 14.9 0.0 0.037 13.5 0.0 1.6 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase NodS PF05401.11 EON98279.1 - 0.036 13.7 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Cons_hypoth95 PF03602.15 EON98279.1 - 0.057 13.1 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 NNMT_PNMT_TEMT PF01234.17 EON98279.1 - 0.069 12.3 0.0 0.13 11.4 0.0 1.5 1 1 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_2 PF00891.18 EON98279.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain BES1_N PF05687.13 EON98280.1 - 0.13 12.7 0.5 0.19 12.1 0.5 1.2 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal TraW_N PF12477.8 EON98280.1 - 2.3 8.3 6.0 15 5.7 0.1 2.5 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal PG_binding_1 PF01471.18 EON98285.1 - 2.2e-09 37.4 0.0 3.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 EON98285.1 - 0.0066 16.7 0.0 0.25 11.6 0.0 2.2 1 1 1 2 2 2 2 Predicted Peptidoglycan domain Aldo_ket_red PF00248.21 EON98286.1 - 2.7e-53 181.1 0.0 3.1e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BBE PF08031.12 EON98287.1 - 6.7e-13 48.5 0.4 6.7e-13 48.5 0.4 2.1 2 1 0 2 2 2 1 Berberine and berberine like Transferase PF02458.15 EON98288.1 - 4.2e-12 45.5 0.0 3.5e-07 29.2 0.0 2.9 3 0 0 3 3 3 3 Transferase family Cu_amine_oxid PF01179.20 EON98289.1 - 1.4e-82 277.8 1.6 1.6e-82 277.6 1.6 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cupin_2 PF07883.11 EON98290.1 - 5.5e-16 58.0 0.6 9.8e-16 57.2 0.6 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EON98290.1 - 2.2e-08 33.8 0.2 3.5e-08 33.2 0.2 1.3 1 1 0 1 1 1 1 Cupin AraC_binding PF02311.19 EON98290.1 - 3.9e-08 33.3 0.1 5.4e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.7 EON98290.1 - 0.0011 18.8 0.0 0.0026 17.5 0.0 1.6 1 1 1 2 2 2 1 Cupin CENP-C_C PF11699.8 EON98290.1 - 0.065 13.5 0.0 0.097 12.9 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like EutQ PF06249.12 EON98290.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ DMSP_lyase PF16867.5 EON98290.1 - 0.11 12.1 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Oxidored_FMN PF00724.20 EON98291.1 - 8.5e-64 216.0 0.0 1.1e-63 215.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EON98291.1 - 0.13 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) AA_permease PF00324.21 EON98292.1 - 6.5e-143 476.8 42.0 1.1e-142 476.0 42.0 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON98292.1 - 4.6e-42 144.3 39.5 5.7e-42 144.0 39.5 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.18 EON98293.1 - 0.0002 20.5 0.0 0.00044 19.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C33 PF05412.12 EON98293.1 - 0.058 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase Glyco_hydro_30 PF02055.16 EON98294.1 - 2e-37 129.0 2.8 3e-37 128.4 2.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 EON98294.1 - 3e-08 33.7 0.2 9.3e-08 32.2 0.2 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 EON98294.1 - 3.7e-06 26.4 0.7 7.1e-06 25.5 0.7 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EON98294.1 - 2e-05 24.4 0.1 3.9e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 AtuA PF07287.11 EON98296.1 - 7.6e-129 429.4 0.4 9.2e-129 429.1 0.4 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA tRNA-synt_2b PF00587.25 EON98297.1 - 4.1e-33 114.8 0.0 1.6e-31 109.7 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EON98297.1 - 2e-07 31.0 0.0 3.5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain AA_kinase PF00696.28 EON98297.1 - 0.18 11.4 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 Amino acid kinase family Ada3 PF10198.9 EON98298.1 - 2.1e-55 186.5 0.0 3.2e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 DUF1772 PF08592.11 EON98299.1 - 4.9e-31 107.9 1.4 6.5e-31 107.5 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Utp11 PF03998.13 EON98300.1 - 1.6e-65 221.5 19.2 1.8e-65 221.3 19.2 1.0 1 0 0 1 1 1 1 Utp11 protein DUF3577 PF12101.8 EON98300.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) DNA_pol_phi PF04931.13 EON98300.1 - 1.7 6.7 14.2 2.3 6.2 14.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 EON98300.1 - 3.4 6.1 8.1 4.3 5.8 8.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 VPS28 PF03997.12 EON98301.1 - 5.4e-69 231.7 0.0 6.2e-69 231.5 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein HMG_box PF00505.19 EON98303.1 - 1.7e-07 31.5 0.1 4.3e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EON98303.1 - 4.2e-05 24.0 0.8 0.0001 22.8 0.0 2.1 2 0 0 2 2 2 1 HMG-box domain Maf PF02545.14 EON98305.1 - 6.6e-50 169.2 0.1 7.9e-50 168.9 0.1 1.1 1 0 0 1 1 1 1 Maf-like protein Pal1 PF08316.11 EON98306.1 - 9.6e-11 42.6 0.7 3.7e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 Pal1 cell morphology protein LNS2 PF08235.13 EON98307.1 - 1.1e-92 309.6 0.0 1.7e-92 309.0 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EON98307.1 - 2.9e-41 139.6 0.0 6.2e-41 138.5 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 EON98307.1 - 0.018 14.7 0.0 0.84 9.2 0.0 2.8 4 0 0 4 4 4 0 HAD superfamily, subfamily IIIB (Acid phosphatase) ubiquitin PF00240.23 EON98308.1 - 5.9e-19 67.6 0.0 8e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EON98308.1 - 1.3e-06 28.2 0.0 3.4e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 EON98308.1 - 3.6e-06 26.7 0.0 5.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EON98308.1 - 0.00019 21.5 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EON98308.1 - 0.0097 16.5 0.0 0.017 15.7 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain GET2 PF08690.10 EON98308.1 - 0.039 13.6 0.0 0.039 13.6 0.0 2.0 2 0 0 2 2 2 0 GET complex subunit GET2 HOIP-UBA PF16678.5 EON98308.1 - 0.066 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair CKS PF01111.19 EON98310.1 - 8.4e-32 109.3 2.4 1.4e-31 108.5 2.4 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF2921 PF11145.8 EON98310.1 - 0.18 9.6 0.0 0.18 9.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-CCCH PF00642.24 EON98311.1 - 5.4e-25 86.7 32.8 7.1e-07 29.0 0.4 5.4 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EON98311.1 - 2.2e-22 78.3 33.1 1.2e-06 28.3 1.9 5.3 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 EON98311.1 - 4e-12 46.8 24.5 0.00012 22.7 0.6 5.3 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 EON98311.1 - 1.4e-10 40.7 35.5 1e-05 25.2 0.4 5.6 5 1 0 5 5 5 5 CCCH-type zinc finger zf-C3H1 PF10650.9 EON98311.1 - 0.009 15.7 10.1 0.5 10.2 1.2 3.8 3 0 0 3 3 3 2 Putative zinc-finger domain zf-CCCH_3 PF15663.5 EON98311.1 - 0.3 11.3 15.3 1.8 8.8 3.3 3.1 1 1 1 2 2 2 0 Zinc-finger containing family GRP PF07172.11 EON98311.1 - 1.1 10.0 16.5 0.43 11.3 13.4 1.8 2 0 0 2 2 2 0 Glycine rich protein family WD40 PF00400.32 EON98312.1 - 1.5e-14 54.1 6.9 1.7e-05 25.5 0.2 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON98312.1 - 1.3e-09 38.2 1.5 0.0024 18.1 0.0 5.2 3 3 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EON98312.1 - 0.00015 21.7 0.0 0.17 11.7 0.0 3.2 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A MFS_1 PF07690.16 EON98313.1 - 1.7e-14 53.5 33.6 1.7e-14 53.5 33.6 3.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EON98313.1 - 3.1e-10 39.1 7.7 9.7e-10 37.5 7.7 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TFIID-31kDa PF02291.15 EON98314.1 - 7.8e-40 135.7 0.0 1e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit fn3 PF00041.21 EON98315.1 - 7.6e-07 29.4 0.2 3e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III domain Pet191_N PF10203.9 EON98315.1 - 0.096 13.0 0.8 0.18 12.1 0.8 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF2407_C PF13373.6 EON98315.1 - 2.4 8.4 6.6 7.1 6.8 6.6 1.8 1 0 0 1 1 1 0 DUF2407 C-terminal domain DAO PF01266.24 EON98316.1 - 1.3e-31 110.4 0.0 1.6e-31 110.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EON98316.1 - 2.2e-06 28.1 0.1 5.9e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EON98316.1 - 6.9e-05 22.2 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON98316.1 - 0.00051 19.2 0.0 0.00078 18.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EON98316.1 - 0.0023 17.3 0.2 0.0039 16.5 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 EON98316.1 - 0.0035 17.0 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 EON98316.1 - 0.0047 17.4 0.0 0.0084 16.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EON98316.1 - 0.0074 15.6 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EON98316.1 - 0.0085 16.3 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EON98316.1 - 0.01 15.0 0.1 0.023 13.8 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EON98316.1 - 0.011 15.0 0.2 0.02 14.1 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EON98316.1 - 0.048 13.5 0.3 0.076 12.9 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EON98316.1 - 0.058 12.1 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 EON98316.1 - 0.058 13.0 0.3 0.092 12.3 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 EON98316.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain tRNA-synt_1b PF00579.25 EON98317.1 - 2e-57 194.7 0.0 2.5e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EON98317.1 - 8.8e-50 167.5 0.0 1.4e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain HR1 PF02185.16 EON98317.1 - 0.047 13.8 0.5 7.8 6.7 0.1 2.5 2 0 0 2 2 2 0 Hr1 repeat Noc2 PF03715.13 EON98318.1 - 6.5e-128 426.2 0.0 1.3e-127 425.1 0.0 1.5 1 0 0 1 1 1 1 Noc2p family RNase_T PF00929.24 EON98319.1 - 0.062 13.8 2.2 1.3 9.6 0.2 2.2 1 1 0 2 2 2 0 Exonuclease DUF1366 PF07104.11 EON98319.1 - 1.4 8.6 8.6 0.16 11.7 2.5 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1366) UPF0242 PF06785.11 EON98319.1 - 2.4 8.2 6.9 1.6 8.8 1.9 2.4 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus EMC3_TMCO1 PF01956.16 EON98319.1 - 6.3 6.5 5.5 6.4 6.5 1.0 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like HVSL PF09749.9 EON98320.1 - 3.3e-84 282.1 0.0 3.8e-84 281.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 EON98320.1 - 0.027 14.4 0.0 0.074 13.0 0.0 1.7 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily Pribosyltran PF00156.27 EON98321.1 - 3.2e-15 56.0 0.0 4.6e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EON98321.1 - 0.0083 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Amidohydro_1 PF01979.20 EON98322.1 - 4.3e-78 263.0 0.3 7.1e-78 262.3 0.3 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 EON98322.1 - 5.3e-55 184.9 4.1 1.1e-54 183.9 1.6 2.3 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 EON98322.1 - 1.1e-41 140.8 0.2 1.9e-41 140.0 0.2 1.4 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 EON98322.1 - 4.2e-22 78.3 0.1 3.4e-21 75.4 0.0 2.4 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_3 PF07969.11 EON98322.1 - 3.4e-09 36.7 0.1 1.5e-05 24.7 0.0 2.3 1 1 1 2 2 2 2 Amidohydrolase family Pyr_redox_2 PF07992.14 EON98324.1 - 4.8e-50 170.4 0.4 6.2e-50 170.1 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON98324.1 - 3e-20 72.5 1.5 6.5e-18 65.1 0.5 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON98324.1 - 5.1e-19 68.7 0.3 2.2e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON98324.1 - 9.8e-06 25.7 0.2 0.019 15.2 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 EON98324.1 - 2e-05 25.0 0.1 0.0087 16.5 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EON98324.1 - 7.2e-05 22.2 1.1 1.7 7.8 0.0 3.1 2 1 1 3 3 3 3 FAD binding domain Thi4 PF01946.17 EON98324.1 - 7.3e-05 22.1 0.1 0.00045 19.5 0.0 2.1 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EON98324.1 - 0.002 17.3 5.3 0.34 9.9 0.3 3.9 3 1 1 4 4 4 1 Glucose inhibited division protein A DAO PF01266.24 EON98324.1 - 0.0024 17.5 0.5 8.4 5.9 0.2 3.2 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EON98324.1 - 0.0025 17.2 0.2 0.028 13.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON98324.1 - 0.0031 16.7 5.5 0.21 10.6 0.5 3.1 3 1 0 4 4 4 2 FAD binding domain K_oxygenase PF13434.6 EON98324.1 - 0.0057 15.8 0.1 0.3 10.2 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 EON98324.1 - 0.027 14.6 1.3 8.8 6.4 0.0 2.9 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 EON98324.1 - 0.033 12.9 1.2 2.5 6.7 0.1 3.1 2 1 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.14 EON98324.1 - 0.12 11.2 0.2 0.43 9.4 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase ERO1 PF04137.15 EON98325.1 - 2.3e-135 451.4 0.0 3.2e-135 450.9 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Cytochrom_B558a PF05038.13 EON98326.1 - 0.0033 17.0 0.1 0.0062 16.1 0.1 1.4 1 0 0 1 1 1 1 Cytochrome Cytochrome b558 alpha-subunit TMEM239 PF15841.5 EON98326.1 - 0.063 13.2 5.4 0.28 11.1 1.2 2.5 2 0 0 2 2 2 0 Transmembrane protein 239 family Glyco_hydro_45 PF02015.16 EON98327.1 - 4.8e-74 248.8 19.7 5.8e-74 248.6 19.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 CssAB PF16831.5 EON98327.1 - 0.043 14.2 0.1 0.071 13.5 0.1 1.4 1 0 0 1 1 1 0 CS6 fimbrial subunits A and B, Coli surface antigen 6 ADH_zinc_N PF00107.26 EON98328.1 - 0.00013 22.0 0.1 0.00036 20.5 0.1 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EON98328.1 - 0.0046 16.3 2.5 0.0046 16.3 2.5 1.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.6 EON98328.1 - 0.038 13.9 0.2 0.058 13.3 0.2 1.3 1 0 0 1 1 1 0 NAD(P)H-binding ELFV_dehydrog PF00208.21 EON98328.1 - 0.059 13.1 0.1 0.097 12.4 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Polysacc_synt_2 PF02719.15 EON98328.1 - 0.15 11.1 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CybS PF05328.12 EON98329.1 - 3e-52 175.8 0.0 3.8e-52 175.5 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Sdh_cyt PF01127.22 EON98329.1 - 0.0036 17.3 0.7 0.038 14.0 0.1 2.0 1 1 1 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit HLH PF00010.26 EON98330.1 - 4e-08 33.1 0.0 8.5e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain BRCT_2 PF16589.5 EON98330.1 - 0.059 13.8 0.2 0.15 12.5 0.1 1.7 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain DUF3006 PF11213.8 EON98330.1 - 0.62 10.3 4.5 8.6 6.7 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3006) Cmc1 PF08583.10 EON98332.1 - 5.6e-12 45.5 0.2 5.6e-12 45.5 0.2 2.8 4 0 0 4 4 4 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF501 PF04417.12 EON98332.1 - 3.4 7.5 6.0 12 5.7 6.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF501) HSP70 PF00012.20 EON98333.1 - 1.8e-228 759.6 8.2 2e-228 759.5 8.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EON98333.1 - 9.4e-18 64.1 0.4 1e-16 60.7 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EON98333.1 - 0.00037 20.3 0.0 0.00079 19.2 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EON98333.1 - 0.032 14.6 1.6 18 5.8 0.0 3.5 3 0 0 3 3 3 0 Cell division protein FtsA DDR PF08841.10 EON98333.1 - 0.041 12.9 0.3 0.38 9.7 0.1 2.2 2 1 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain MMM1 PF10296.9 EON98334.1 - 2.4e-05 23.5 0.0 5.1e-05 22.5 0.0 1.4 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Neil1-DNA_bind PF09292.10 EON98335.1 - 0.59 10.1 3.1 0.74 9.8 0.3 2.3 2 0 0 2 2 2 0 Endonuclease VIII-like 1, DNA bind DUF3419 PF11899.8 EON98336.1 - 2.2e-165 550.6 0.0 2.8e-165 550.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 EON98336.1 - 1.8e-15 57.2 0.0 2.8e-14 53.3 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON98336.1 - 2.9e-09 37.6 0.0 1.1e-08 35.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON98336.1 - 5.6e-09 36.6 0.0 6.9e-07 29.9 0.0 3.6 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON98336.1 - 8.7e-09 35.3 0.0 7.7e-08 32.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON98336.1 - 5.4e-07 30.2 0.0 7e-05 23.4 0.0 3.7 4 0 0 4 4 4 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON98336.1 - 1e-05 25.0 0.0 0.00091 18.6 0.0 2.7 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EON98336.1 - 0.0011 18.8 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_28 PF02636.17 EON98336.1 - 0.13 11.9 0.0 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 EON98336.1 - 0.14 11.6 0.0 0.91 9.0 0.0 2.3 3 0 0 3 3 3 0 Putative methyltransferase PIP5K PF01504.18 EON98337.1 - 5.2e-35 121.0 0.2 3.1e-26 92.2 0.3 2.9 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EON98337.1 - 8e-20 70.9 0.0 1.2e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Aldedh PF00171.22 EON98338.1 - 1.3e-67 228.3 0.0 1.5e-67 228.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Bromodomain PF00439.25 EON98339.1 - 4.1e-36 122.9 0.9 3.9e-18 65.3 0.2 2.5 2 0 0 2 2 2 2 Bromodomain XhlA PF10779.9 EON98339.1 - 0.11 12.8 1.1 0.2 11.9 0.1 2.0 2 0 0 2 2 2 0 Haemolysin XhlA BUD22 PF09073.10 EON98339.1 - 0.13 11.6 8.9 0.19 11.0 8.9 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EON98339.1 - 0.14 10.4 8.7 0.18 10.0 8.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EON98339.1 - 0.3 9.3 4.6 0.43 8.8 4.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 EON98339.1 - 1.3 8.7 8.1 2.6 7.8 8.1 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FYDLN_acid PF09538.10 EON98339.1 - 2.7 8.7 14.7 10 6.9 14.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) IBN_N PF03810.19 EON98340.1 - 7.6e-15 54.6 0.6 5.9e-14 51.7 0.0 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EON98340.1 - 7.8e-05 22.8 0.3 0.0016 18.5 0.0 3.1 2 0 0 2 2 2 1 Exportin 1-like protein HET PF06985.11 EON98341.1 - 2e-30 106.1 0.0 2.4e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1930 PF09122.10 EON98341.1 - 0.022 14.8 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1930) Histidinol_dh PF00815.20 EON98342.1 - 9.5e-136 453.0 5.6 1.4e-135 452.5 5.6 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 EON98342.1 - 5.1e-25 87.1 0.1 9.9e-25 86.2 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EON98342.1 - 4.8e-13 49.4 0.9 1.2e-12 48.1 0.1 2.2 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Glyco_hydro_47 PF01532.20 EON98344.1 - 1.2e-83 281.6 0.0 1.8e-83 281.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GH43_C2 PF17851.1 EON98345.1 - 7.2e-23 81.4 0.4 9.7e-23 80.9 0.4 1.1 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain adh_short_C2 PF13561.6 EON98347.1 - 1.6e-54 185.0 0.5 1.8e-54 184.8 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON98347.1 - 1.7e-42 145.1 0.1 2.1e-42 144.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON98347.1 - 1.1e-08 35.2 0.1 1.5e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 KR domain PALP PF00291.25 EON98347.1 - 0.0043 16.5 0.2 0.0064 15.9 0.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribosomal_L12 PF00542.19 EON98347.1 - 0.055 13.8 0.8 0.11 12.9 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain DUF1776 PF08643.10 EON98348.1 - 3.6e-108 361.4 0.0 5e-108 361.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 EON98348.1 - 0.0087 15.5 0.0 0.031 13.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase ING PF12998.7 EON98348.1 - 0.065 13.8 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding RNA_pol_Rpb1_1 PF04997.12 EON98349.1 - 3.6e-107 358.3 0.0 6.3e-107 357.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EON98349.1 - 5.9e-100 334.1 0.0 1.1e-99 333.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EON98349.1 - 1.5e-76 256.2 0.0 3.5e-76 255.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EON98349.1 - 2.6e-64 216.6 0.8 4.6e-64 215.8 0.8 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EON98349.1 - 2.7e-48 163.9 0.0 6.7e-48 162.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EON98349.1 - 2.6e-47 160.2 8.1 5.8e-47 159.1 8.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EON98349.1 - 1.5e-36 124.6 0.0 3.2e-36 123.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 F-box PF00646.33 EON98350.1 - 0.066 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 F-box domain NPR2 PF06218.11 EON98351.1 - 1.3e-127 426.2 2.8 1.4e-106 356.9 1.2 2.3 1 1 1 2 2 2 2 Nitrogen permease regulator 2 ANAPC4 PF12896.7 EON98351.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 RGS12_usC PF16612.5 EON98352.1 - 0.28 11.6 6.3 3.4 8.1 0.5 3.2 2 1 1 3 3 3 0 C-terminal unstructured region of RGS12 Het-C PF07217.11 EON98353.1 - 6.1e-243 807.4 0.1 7.2e-243 807.2 0.1 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Methyltransf_25 PF13649.6 EON98354.1 - 5.8e-12 46.2 0.0 8.7e-11 42.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON98354.1 - 9.6e-10 38.5 0.0 1.7e-09 37.6 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON98354.1 - 1.1e-08 35.6 0.0 5.4e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON98354.1 - 3.5e-07 30.9 0.0 7.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON98354.1 - 0.0019 18.0 0.0 0.004 17.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Vps53_N PF04100.12 EON98355.1 - 4.8e-102 341.8 0.9 1e-101 340.7 0.9 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2451 PF10474.9 EON98355.1 - 4.2e-07 30.0 0.1 9.7e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) RINT1_TIP1 PF04437.13 EON98355.1 - 1.2e-05 24.4 0.1 0.01 14.8 0.0 2.6 3 0 0 3 3 3 2 RINT-1 / TIP-1 family Vps54_N PF10475.9 EON98355.1 - 0.0001 21.7 4.0 0.0002 20.8 4.0 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 EON98355.1 - 0.0014 17.3 1.6 0.0014 17.3 1.6 1.7 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 DUF3510 PF12022.8 EON98355.1 - 0.0061 16.9 0.2 0.052 13.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) Spc7 PF08317.11 EON98355.1 - 0.0077 15.1 1.6 0.015 14.2 1.6 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF5082 PF16888.5 EON98355.1 - 0.0087 16.3 3.5 1.6 9.0 0.2 2.8 3 0 0 3 3 2 2 Domain of unknown function (DUF5082) Sec15 PF04091.12 EON98355.1 - 0.038 13.4 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like DUF1664 PF07889.12 EON98355.1 - 0.051 13.6 0.2 0.16 12.0 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2939 PF11159.8 EON98355.1 - 0.11 13.0 0.1 1.9 8.9 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) Thg1C PF14413.6 EON98356.1 - 2.9e-23 82.3 2.0 3.5e-23 82.1 2.0 1.1 1 0 0 1 1 1 1 Thg1 C terminal domain DUF848 PF05852.11 EON98357.1 - 0.048 13.8 2.1 0.1 12.7 0.5 2.3 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) RIX1 PF08167.12 EON98357.1 - 0.1 12.3 1.3 0.18 11.5 0.3 1.8 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Glyco_hydro_47 PF01532.20 EON98358.1 - 1.5e-179 597.7 0.1 1.8e-179 597.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Amidase PF01425.21 EON98359.1 - 3.4e-95 319.7 0.0 6e-95 318.8 0.0 1.4 1 1 0 1 1 1 1 Amidase NB-ARC PF00931.22 EON98359.1 - 0.18 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain 2OG-FeII_Oxy PF03171.20 EON98360.1 - 9.8e-15 54.9 0.0 1.7e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Headcase PF16002.5 EON98360.1 - 0.21 11.0 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Headcase protein 2OG-FeII_Oxy_3 PF13640.6 EON98361.1 - 5e-07 30.5 0.0 1e-06 29.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 EON98362.1 - 1.7e-28 99.5 29.8 1.7e-28 99.5 29.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON98362.1 - 1.8e-11 43.6 10.3 1.8e-11 43.6 10.3 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter Phage_holin_5_2 PF16079.5 EON98362.1 - 7.2 7.0 17.2 1.9 8.9 0.2 5.0 5 0 0 5 5 5 0 Phage holin family Hol44, in holin superfamily V OPT PF03169.15 EON98363.1 - 7.2e-120 401.5 37.6 8.4e-120 401.2 37.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SNARE_assoc PF09335.11 EON98363.1 - 0.28 11.7 12.4 0.48 10.9 4.2 3.8 3 0 0 3 3 3 0 SNARE associated Golgi protein CrgA PF06781.12 EON98363.1 - 1.8 8.7 5.0 1 9.5 0.2 2.9 3 0 0 3 3 3 0 Cell division protein CrgA TPT PF03151.16 EON98364.1 - 1.6e-25 90.0 23.3 2e-25 89.8 23.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EON98364.1 - 6e-05 22.4 20.4 0.001 18.4 20.4 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EON98364.1 - 2.1 8.5 39.8 0.53 10.4 12.4 2.5 3 0 0 3 3 3 0 EamA-like transporter family Acyl-CoA_dh_1 PF00441.24 EON98365.1 - 1.9e-30 106.1 2.4 2.7e-30 105.6 2.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON98365.1 - 1e-21 76.9 0.2 2e-21 76.0 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EON98365.1 - 1e-08 35.8 0.4 3.2e-07 31.0 0.0 2.9 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EON98365.1 - 4.7e-06 26.9 0.2 7.3e-06 26.3 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain LamB_YcsF PF03746.16 EON98366.1 - 1.8e-58 198.0 0.0 2e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family DUF2274 PF10038.9 EON98368.1 - 0.22 12.0 0.2 2.3 8.7 0.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2274) DUF417 PF04224.12 EON98368.1 - 1.2 8.7 6.1 0.31 10.6 1.8 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF417 EthD PF07110.11 EON98369.1 - 4.3e-23 82.3 1.5 5.3e-23 82.0 1.5 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 EON98369.1 - 0.00023 21.6 0.2 0.00043 20.7 0.2 1.5 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase AMP-binding PF00501.28 EON98370.1 - 8.4e-29 100.4 0.2 1e-28 100.1 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON98370.1 - 4.3e-16 59.7 0.0 7.5e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNase_Zc3h12a PF11977.8 EON98370.1 - 0.2 11.4 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Methyltransf_23 PF13489.6 EON98371.1 - 4.5e-13 49.4 0.0 6.9e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON98371.1 - 1e-07 31.9 0.0 3.3e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON98371.1 - 1.2e-05 26.0 0.0 6.7e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON98371.1 - 0.00011 22.8 0.0 0.00024 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON98371.1 - 0.00028 21.5 0.0 0.00056 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EON98371.1 - 0.042 13.3 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Acetyltransf_1 PF00583.25 EON98372.1 - 9.5e-05 22.6 0.0 0.00018 21.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON98372.1 - 0.00053 20.4 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EON98372.1 - 0.00098 19.1 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CT_C_D PF02682.16 EON98374.1 - 5.1e-25 88.4 0.0 8.8e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_lipoyl PF00364.22 EON98374.1 - 4.9e-10 39.1 4.4 5.4e-10 39.0 1.2 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EON98374.1 - 6e-05 22.8 1.0 0.0091 15.8 0.2 2.3 1 1 1 2 2 2 2 Biotin-lipoyl like Cep57_CLD PF14073.6 EON98374.1 - 0.06 13.4 1.0 0.098 12.7 1.0 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 EMP24_GP25L PF01105.24 EON98374.1 - 0.07 13.1 0.3 2.3 8.1 0.3 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Lebercilin PF15619.6 EON98374.1 - 0.077 12.7 0.5 0.12 12.0 0.5 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease CT_A_B PF02626.15 EON98374.1 - 0.13 11.9 0.0 0.59 9.7 0.0 2.0 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain A and B adh_short PF00106.25 EON98375.1 - 1.3e-85 285.7 13.1 1.1e-44 152.3 1.4 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON98375.1 - 1.6e-64 217.6 11.4 4e-34 118.2 0.9 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EON98375.1 - 3.6e-27 94.4 0.0 8.2e-27 93.2 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 EON98375.1 - 5.4e-25 88.3 6.8 1.2e-13 51.3 2.1 2.5 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 EON98375.1 - 4.8e-08 33.2 0.0 0.00026 21.1 0.0 2.6 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 EON98375.1 - 0.0078 15.5 2.4 0.54 9.6 0.3 2.6 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 EON98375.1 - 0.067 12.6 1.4 0.25 10.8 0.2 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 EON98375.1 - 0.076 13.1 4.9 1.4 9.0 0.5 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MFS_1 PF07690.16 EON98376.1 - 1.5e-21 76.8 4.5 1.5e-21 76.8 4.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Voltage_CLC PF00654.20 EON98376.1 - 0.013 14.8 17.9 0.021 14.1 13.0 2.1 2 0 0 2 2 2 0 Voltage gated chloride channel Glyco_hydro_cc PF11790.8 EON98377.1 - 4.8e-65 219.5 0.6 5.7e-65 219.2 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core CorA PF01544.18 EON98379.1 - 0.0015 17.9 5.5 0.0041 16.5 5.4 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein 7TM_GPCR_Srw PF10324.9 EON98379.1 - 0.085 12.1 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw ELYS PF13934.6 EON98380.1 - 1.8e-71 240.6 0.1 2.2e-71 240.4 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly NmrA PF05368.13 EON98381.1 - 8e-17 61.6 0.3 1.1e-16 61.1 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EON98381.1 - 2.5e-15 56.8 0.9 3.5e-15 56.4 0.7 1.4 1 1 0 1 1 1 1 NAD(P)H-binding DFP PF04127.15 EON98381.1 - 0.00017 21.5 2.6 0.25 11.1 0.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Semialdhyde_dh PF01118.24 EON98381.1 - 0.0002 21.8 1.8 0.0051 17.2 0.9 2.5 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EON98381.1 - 0.00093 18.7 0.2 0.0019 17.7 0.2 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EON98381.1 - 0.02 14.4 0.2 0.04 13.4 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.12 EON98381.1 - 0.034 13.3 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein DapB_N PF01113.20 EON98381.1 - 0.037 14.1 0.1 0.074 13.2 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3HCDH_N PF02737.18 EON98381.1 - 0.074 12.9 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 EON98382.1 - 1.4e-40 139.3 0.0 1.8e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON98382.1 - 6.8e-26 91.5 0.0 9.3e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HMGL-like PF00682.19 EON98382.1 - 8.4e-25 87.8 0.0 1.3e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 HMGL-like K_oxygenase PF13434.6 EON98383.1 - 1.9e-07 30.6 0.0 0.00014 21.1 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 EON98383.1 - 5.1e-07 28.5 0.0 9.9e-05 20.9 0.0 2.4 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EON98383.1 - 0.00021 21.5 0.1 0.00074 19.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EON98383.1 - 0.0013 18.1 0.0 0.099 11.9 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EON98383.1 - 0.023 14.1 0.0 0.053 12.9 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF498 PF04430.14 EON98383.1 - 0.05 13.7 0.0 18 5.4 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF498/DUF598) Shikimate_DH PF01488.20 EON98383.1 - 0.091 12.8 0.0 0.43 10.6 0.0 2.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 EON98383.1 - 0.1 12.6 0.0 26 4.8 0.0 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding SprB PF13573.6 EON98383.1 - 1.1 9.1 6.9 0.15 11.8 1.4 2.2 2 0 0 2 2 2 0 SprB repeat adh_short PF00106.25 EON98384.1 - 4.8e-38 130.6 0.0 6.4e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON98384.1 - 2.3e-28 99.3 0.0 3.1e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON98384.1 - 6.3e-05 23.0 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 EON98384.1 - 0.025 14.6 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EON98384.1 - 0.056 14.0 0.1 0.11 13.1 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 EON98384.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4064 PF13273.6 EON98385.1 - 0.64 10.3 16.7 1.3 9.3 3.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) Pyr_redox_3 PF13738.6 EON98386.1 - 6.5e-20 71.6 0.0 4.2e-17 62.4 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EON98386.1 - 2e-16 59.5 0.0 4.8e-12 45.1 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EON98386.1 - 3.9e-15 55.9 0.0 1.8e-12 47.1 0.0 2.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON98386.1 - 5.2e-09 35.7 0.4 1.9e-06 27.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EON98386.1 - 1e-05 25.0 0.3 0.006 15.9 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 EON98386.1 - 1.5e-05 25.4 0.7 0.31 11.6 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON98386.1 - 0.00024 20.3 0.2 4.4 6.3 0.0 3.1 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EON98386.1 - 0.00026 21.2 0.3 0.015 15.5 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EON98386.1 - 0.0019 17.9 1.1 0.037 13.6 1.1 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 EON98386.1 - 0.002 17.5 0.0 0.22 10.9 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EON98386.1 - 0.0042 17.1 0.1 0.21 11.6 0.0 2.5 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EON98386.1 - 0.013 15.9 0.1 0.24 11.9 0.1 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 EON98386.1 - 0.032 14.1 0.3 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EON98386.1 - 0.042 13.5 0.3 0.69 9.6 0.0 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 EON98386.1 - 0.077 12.2 0.1 3.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Thi4 family THF_DHG_CYH_C PF02882.19 EON98386.1 - 0.19 11.0 0.2 2.1 7.6 0.1 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.12 EON98386.1 - 0.19 10.7 0.1 0.9 8.5 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 EON98386.1 - 0.21 11.8 0.4 6.4 7.1 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain Thiolase_C PF02803.18 EON98387.1 - 1.7e-10 40.6 0.4 2.7e-09 36.7 0.4 2.3 1 1 1 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 EON98387.1 - 2.1e-10 40.4 0.1 1.6e-08 34.2 0.0 2.9 2 1 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EON98387.1 - 5.2e-06 26.2 0.0 7.6e-05 22.5 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EON98387.1 - 0.00017 21.3 0.1 0.00038 20.1 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EON98387.1 - 0.067 13.2 0.0 0.52 10.3 0.0 2.2 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain DUF3208 PF11482.8 EON98387.1 - 0.18 12.1 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) SnoaL_2 PF12680.7 EON98388.1 - 0.00013 22.6 0.0 0.00015 22.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EON98388.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase DUF5597 PF18120.1 EON98389.1 - 8.4e-29 100.4 0.1 1.3e-28 99.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 EON98389.1 - 3.9e-12 46.2 0.0 6.1e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 EON98389.1 - 8.4e-08 32.2 0.0 7.9e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.20 EON98389.1 - 0.2 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 adh_short_C2 PF13561.6 EON98390.1 - 1.7e-53 181.6 0.0 2.1e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON98390.1 - 1.4e-48 164.9 0.2 1.8e-48 164.6 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON98390.1 - 1.2e-13 51.3 0.1 1.7e-13 50.9 0.1 1.1 1 0 0 1 1 1 1 KR domain AlaDh_PNT_C PF01262.21 EON98390.1 - 0.039 13.2 1.1 0.1 11.9 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 EON98390.1 - 0.048 14.4 0.0 0.082 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 EON98390.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Epimerase PF01370.21 EON98390.1 - 0.14 11.6 0.3 1.2 8.5 0.3 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EON98390.1 - 0.17 11.8 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CoA_transf_3 PF02515.17 EON98391.1 - 9.8e-102 340.8 0.0 1.2e-101 340.5 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Peptidase_M19 PF01244.21 EON98392.1 - 4.6e-46 157.5 0.1 5.2e-46 157.3 0.1 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF3071 PF11268.8 EON98392.1 - 0.083 13.0 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) COesterase PF00135.28 EON98393.1 - 2.1e-22 79.7 0.0 3.5e-22 79.0 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family CN_hydrolase PF00795.22 EON98394.1 - 8.4e-39 133.5 0.0 1e-38 133.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AMP-binding PF00501.28 EON98395.1 - 2.9e-16 59.1 0.5 2e-13 49.8 0.0 2.3 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EON98395.1 - 1.3e-05 26.0 0.1 2.7e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.24 EON98396.1 - 1.5e-65 221.9 20.4 1.9e-65 221.5 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON98396.1 - 8.3e-16 57.8 52.5 9.7e-10 37.9 35.6 2.3 1 1 2 3 3 3 3 Major Facilitator Superfamily ABC_tran PF00005.27 EON98397.1 - 3e-65 218.9 0.0 3.8e-32 111.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EON98397.1 - 1.1e-39 136.8 16.1 1.6e-39 136.3 16.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EON98397.1 - 1.2e-16 60.8 1.1 8.8e-05 22.0 0.0 4.3 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EON98397.1 - 5.2e-09 35.7 0.2 0.0033 17.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EON98397.1 - 2.5e-06 28.1 0.9 0.015 15.8 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_21 PF13304.6 EON98397.1 - 4.7e-06 26.6 0.8 0.22 11.3 0.0 3.6 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 EON98397.1 - 1.5e-05 25.2 2.4 0.0064 16.6 0.0 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain DUF3987 PF13148.6 EON98397.1 - 4.1e-05 22.8 0.1 0.37 9.8 0.0 2.8 3 0 0 3 3 2 2 Protein of unknown function (DUF3987) AAA_22 PF13401.6 EON98397.1 - 4.9e-05 23.6 2.0 0.38 11.0 0.3 3.8 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EON98397.1 - 5e-05 23.8 6.6 0.13 12.6 1.9 3.2 2 2 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 EON98397.1 - 5.6e-05 22.5 0.0 0.051 12.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 EON98397.1 - 5.6e-05 23.1 0.1 0.59 10.0 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 EON98397.1 - 8.8e-05 21.5 1.7 0.019 13.8 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA PF00004.29 EON98397.1 - 0.00011 22.6 0.2 5.9 7.3 0.0 4.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EON98397.1 - 0.00013 21.7 6.6 0.059 13.1 0.2 3.9 3 1 0 3 3 3 1 AAA domain APS_kinase PF01583.20 EON98397.1 - 0.00018 21.4 0.0 0.062 13.2 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.6 EON98397.1 - 0.0016 18.6 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EON98397.1 - 0.0018 18.3 0.0 4.1 7.4 0.0 3.3 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EON98397.1 - 0.0018 18.8 0.1 2.4 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EON98397.1 - 0.0018 18.5 3.8 2.1 8.6 0.4 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Cytidylate_kin PF02224.18 EON98397.1 - 0.01 15.6 0.9 0.81 9.4 0.1 2.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_27 PF13514.6 EON98397.1 - 0.034 13.7 0.0 1.6 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EON98397.1 - 0.042 13.6 0.0 8.9 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain Tex_YqgF PF16921.5 EON98397.1 - 0.05 14.1 0.2 0.13 12.7 0.2 1.7 1 0 0 1 1 1 0 Tex protein YqgF-like domain AAA_7 PF12775.7 EON98397.1 - 0.053 13.0 0.3 3.2 7.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EON98397.1 - 0.053 12.9 0.0 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family PRK PF00485.18 EON98397.1 - 0.057 13.2 0.1 7.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 EON98397.1 - 0.059 12.9 2.9 2.5 7.6 0.0 3.6 4 0 0 4 4 4 0 AAA domain ATP-synt_ab PF00006.25 EON98397.1 - 0.071 12.8 0.0 0.86 9.2 0.0 2.5 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 EON98397.1 - 0.074 13.1 0.2 22 5.1 0.1 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rad17 PF03215.15 EON98397.1 - 0.074 13.0 0.0 24 4.8 0.0 2.9 4 0 0 4 4 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 EON98397.1 - 0.077 13.4 0.1 23 5.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Gtr1_RagA PF04670.12 EON98397.1 - 0.078 12.3 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region NB-ARC PF00931.22 EON98397.1 - 0.085 12.0 0.2 12 4.9 0.0 2.5 3 0 0 3 3 2 0 NB-ARC domain Mg_chelatase PF01078.21 EON98397.1 - 0.087 12.2 0.1 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 EON98397.1 - 0.15 11.5 0.1 30 3.9 0.0 3.6 4 0 0 4 4 4 0 Bacterial TniB protein HopA1 PF17914.1 EON98397.1 - 0.15 11.8 0.9 0.57 9.9 0.2 2.0 2 0 0 2 2 2 0 HopA1 effector protein family AAA_15 PF13175.6 EON98397.1 - 0.16 11.7 0.2 1.9 8.1 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain ATP_bind_1 PF03029.17 EON98397.1 - 0.23 11.2 0.7 20 4.9 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Tannase PF07519.11 EON98398.1 - 9.1e-102 341.4 0.5 1.5e-101 340.7 0.5 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase Inhibitor_I9 PF05922.16 EON98399.1 - 2.1e-19 70.0 0.0 3.6e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 EON98399.1 - 1.8e-06 27.5 0.3 2.9e-06 26.7 0.3 1.3 1 1 0 1 1 1 1 Subtilase family Glyco_hydro_17 PF00332.18 EON98400.1 - 2.4e-07 30.6 0.4 3.2e-07 30.2 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 ADH_zinc_N PF00107.26 EON98401.1 - 2.4e-11 43.7 0.0 4.7e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON98401.1 - 2.7e-06 27.2 0.0 7.4e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AA_permease PF00324.21 EON98403.1 - 8.8e-102 341.1 28.0 1.1e-101 340.9 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON98403.1 - 5.9e-32 111.0 29.9 7.1e-32 110.8 29.9 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0014 PF03649.13 EON98403.1 - 7.1 5.9 12.1 1.8 7.9 0.0 3.6 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0014) DUF3619 PF12279.8 EON98404.1 - 0.1 12.9 0.5 0.3 11.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) MFS_1 PF07690.16 EON98404.1 - 0.28 10.1 10.2 0.088 11.7 6.8 1.7 2 0 0 2 2 2 0 Major Facilitator Superfamily Amidohydro_1 PF01979.20 EON98405.1 - 5.6e-23 81.8 0.0 1.5e-22 80.4 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EON98405.1 - 1e-17 64.8 0.1 4.6e-08 33.0 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.20 EON98405.1 - 0.022 15.1 1.8 0.15 12.4 0.7 2.7 2 1 1 3 3 3 0 Urease alpha-subunit, N-terminal domain Methyltransf_25 PF13649.6 EON98406.1 - 9.3e-17 61.5 0.0 1.7e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON98406.1 - 1.2e-14 54.5 0.0 1.8e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON98406.1 - 9.3e-12 45.4 0.0 1.4e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON98406.1 - 2.2e-08 34.7 0.0 3.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON98406.1 - 8.3e-07 28.9 0.0 1.8e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EON98406.1 - 5.8e-06 25.9 0.0 7.6e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 EON98406.1 - 4.7e-05 22.8 0.0 6.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EON98406.1 - 6.7e-05 22.5 0.0 0.00018 21.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.11 EON98406.1 - 0.00017 21.3 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_19 PF04672.12 EON98406.1 - 0.00022 20.8 0.0 0.19 11.2 0.0 2.1 1 1 1 2 2 2 2 S-adenosyl methyltransferase PCMT PF01135.19 EON98406.1 - 0.00071 19.4 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FmrO PF07091.11 EON98406.1 - 0.0047 16.5 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) UDPG_MGDP_dh_N PF03721.14 EON98406.1 - 0.011 15.3 0.1 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_PK PF05891.12 EON98406.1 - 0.012 15.1 0.0 0.027 14.0 0.0 1.5 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase Peripla_BP_4 PF13407.6 EON98406.1 - 0.02 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain MetW PF07021.12 EON98406.1 - 0.022 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW N2227 PF07942.12 EON98406.1 - 0.037 13.2 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein Ubie_methyltran PF01209.18 EON98406.1 - 0.042 13.2 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EON98406.1 - 0.095 12.8 0.0 0.19 11.8 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Mur_ligase PF01225.25 EON98406.1 - 0.11 12.9 0.0 0.36 11.2 0.0 1.8 2 0 0 2 2 2 0 Mur ligase family, catalytic domain Methyltransf_9 PF08003.11 EON98406.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 EON98406.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 EON98406.1 - 0.18 11.7 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_A4 PF01828.17 EON98407.1 - 5.1e-82 274.4 16.4 6.2e-82 274.1 16.4 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF1098 PF06497.11 EON98407.1 - 0.058 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1098) APH PF01636.23 EON98408.1 - 6e-09 36.2 0.0 8.9e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EON98408.1 - 8.1e-08 31.9 0.0 2.2e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EON98408.1 - 0.0059 15.5 0.0 0.0084 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Acyl-CoA_dh_1 PF00441.24 EON98409.1 - 3.1e-38 131.3 2.6 4.3e-38 130.9 1.9 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON98409.1 - 5.5e-16 58.6 0.1 1.3e-15 57.3 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON98409.1 - 1.1e-12 48.4 0.9 1.8e-12 47.7 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON98409.1 - 2.6e-09 37.7 0.0 2.4e-08 34.6 0.0 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 EON98409.1 - 0.033 13.8 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal APH PF01636.23 EON98410.1 - 1e-27 97.6 0.0 1.3e-27 97.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EON98410.1 - 0.0062 16.1 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 2 RIO1 family Acyl-CoA_dh_1 PF00441.24 EON98411.1 - 3.3e-33 115.0 2.2 5.3e-33 114.3 2.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON98411.1 - 1.9e-26 92.9 0.0 3.8e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON98411.1 - 4.3e-19 68.5 0.0 7.3e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON98411.1 - 7.7e-14 52.1 0.1 2.6e-13 50.4 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Glucosaminidase PF01832.20 EON98411.1 - 0.018 15.5 0.1 0.076 13.5 0.0 2.0 2 0 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase ANAPC15 PF15243.6 EON98412.1 - 0.012 16.0 4.1 0.026 14.9 4.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 ATP-cone PF03477.16 EON98412.1 - 0.029 14.9 0.1 0.094 13.3 0.1 1.8 1 0 0 1 1 1 0 ATP cone domain DUF2796 PF10986.8 EON98412.1 - 0.13 12.2 1.0 0.22 11.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Fungal_trans PF04082.18 EON98413.1 - 8.8e-22 77.4 0.3 1.3e-21 76.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Arrestin_C PF02752.22 EON98414.1 - 0.002 18.6 0.0 1.3 9.4 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain SnoaL_4 PF13577.6 EON98415.1 - 7.9e-22 77.7 1.3 9.7e-22 77.4 1.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 EON98415.1 - 8.3e-05 23.2 1.6 0.00013 22.5 1.6 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EON98415.1 - 0.054 13.9 0.8 0.079 13.4 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Binary_toxB PF03495.14 EON98416.1 - 0.017 15.3 1.2 0.072 13.3 0.1 2.5 2 0 0 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain TSP_3 PF02412.18 EON98416.1 - 0.13 12.0 1.1 3.2 7.5 0.1 2.8 2 0 0 2 2 2 0 Thrombospondin type 3 repeat MFS_1 PF07690.16 EON98417.1 - 7e-32 110.7 29.7 7e-32 110.7 29.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily ABC2_membrane PF01061.24 EON98418.1 - 6.3e-39 133.6 20.9 8.5e-39 133.1 20.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EON98418.1 - 3.3e-16 60.0 0.3 5.6e-16 59.3 0.1 1.5 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 EON98418.1 - 5.3e-06 26.5 0.3 0.037 13.8 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EON98418.1 - 1.3e-05 25.7 0.0 2.8e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EON98418.1 - 2.1e-05 24.7 0.0 4.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EON98418.1 - 0.00012 22.5 0.1 0.00023 21.6 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EON98418.1 - 0.00013 21.9 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EON98418.1 - 0.00043 19.8 0.1 0.036 13.5 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EON98418.1 - 0.0006 20.1 0.1 0.0017 18.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EON98418.1 - 0.0026 17.4 0.1 0.0048 16.5 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EON98418.1 - 0.0061 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EON98418.1 - 0.0071 16.6 0.5 0.049 13.9 0.1 2.5 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 EON98418.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 EON98418.1 - 0.012 15.3 0.0 0.043 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EON98418.1 - 0.017 14.8 0.1 0.04 13.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EON98418.1 - 0.021 14.9 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.6 EON98418.1 - 0.039 14.4 0.0 0.093 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EON98418.1 - 0.04 13.8 0.2 0.088 12.7 0.2 1.6 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.23 EON98418.1 - 0.047 13.8 0.1 0.62 10.1 0.0 2.2 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 EON98418.1 - 0.071 12.5 0.1 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.18 EON98418.1 - 0.073 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Septin FliG_C PF01706.16 EON98418.1 - 0.094 12.9 0.0 0.64 10.2 0.0 2.3 2 0 0 2 2 2 0 FliG C-terminal domain PduV-EutP PF10662.9 EON98418.1 - 0.11 12.2 0.2 0.25 11.1 0.2 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation APS_kinase PF01583.20 EON98418.1 - 0.13 12.2 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_13 PF13166.6 EON98418.1 - 0.14 10.8 0.4 1.5 7.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EON98418.1 - 0.19 11.3 0.1 0.33 10.5 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B GMC_oxred_N PF00732.19 EON98419.1 - 1.4e-77 261.0 0.0 2.2e-77 260.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EON98419.1 - 7.6e-34 117.3 0.0 1.7e-33 116.2 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EON98419.1 - 0.00015 21.0 0.1 0.00022 20.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EON98419.1 - 0.0022 17.2 0.0 0.85 8.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EON98419.1 - 0.0028 17.0 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EON98419.1 - 0.012 14.9 0.0 0.033 13.4 0.0 1.6 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 EON98419.1 - 0.06 12.9 2.4 0.39 10.2 1.7 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase Elongin_A PF06881.11 EON98419.1 - 0.08 13.5 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A MARVEL PF01284.23 EON98420.1 - 1.5e-05 25.0 12.3 2e-05 24.7 12.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain FMO-like PF00743.19 EON98421.1 - 1.7e-19 69.6 0.7 1.5e-18 66.6 0.3 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EON98421.1 - 3.2e-18 66.0 0.1 9.9e-17 61.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EON98421.1 - 4.9e-15 55.5 0.0 7.6e-13 48.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON98421.1 - 1.7e-11 44.2 0.0 1e-09 38.5 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EON98421.1 - 4.6e-10 39.2 1.7 1.4e-08 34.3 0.1 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EON98421.1 - 1.7e-09 37.8 0.9 7.6e-05 22.4 0.5 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 EON98421.1 - 1.5e-06 27.7 0.1 0.0026 17.1 0.0 2.5 2 0 0 2 2 2 2 Thi4 family FAD_oxidored PF12831.7 EON98421.1 - 1.5e-06 27.8 0.0 2.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EON98421.1 - 5.9e-06 26.7 0.2 0.0031 18.0 0.2 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON98421.1 - 2.6e-05 23.5 0.4 0.00083 18.5 0.3 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EON98421.1 - 0.0001 21.7 0.3 0.0076 15.5 0.3 2.5 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 EON98421.1 - 0.00035 20.0 0.4 0.0026 17.1 0.1 2.3 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EON98421.1 - 0.00035 19.8 0.1 0.0011 18.1 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EON98421.1 - 0.0012 17.6 0.1 0.0066 15.2 0.1 2.1 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.12 EON98421.1 - 0.0014 17.8 0.1 0.11 11.5 0.1 2.8 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 EON98421.1 - 0.0017 18.4 0.8 0.016 15.2 0.0 2.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 EON98421.1 - 0.0025 17.2 2.5 0.003 16.9 0.2 2.2 3 1 1 4 4 4 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EON98421.1 - 0.017 14.5 0.0 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EON98421.1 - 0.08 12.9 0.7 2.2 8.3 0.1 3.1 3 1 1 4 4 4 0 FAD-NAD(P)-binding NAD_binding_2 PF03446.15 EON98421.1 - 0.085 13.0 0.0 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EON98421.1 - 0.13 12.3 0.1 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SMC_N PF02463.19 EON98422.1 - 9.6e-68 227.9 37.2 1.3e-66 224.2 37.2 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EON98422.1 - 9.9e-25 87.1 0.0 4.5e-24 85.0 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EON98422.1 - 9.9e-11 42.0 6.9 6.1e-05 23.0 0.0 3.6 5 0 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EON98422.1 - 1.6e-08 35.3 7.8 1.6e-08 35.3 7.8 7.3 2 2 3 5 5 5 1 AAA domain Tektin PF03148.14 EON98422.1 - 2.1e-06 26.8 16.8 2.1e-06 26.8 16.8 6.4 3 2 2 5 5 5 1 Tektin family AAA_29 PF13555.6 EON98422.1 - 0.00064 19.4 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RT_RNaseH PF17917.1 EON98422.1 - 0.0024 18.1 0.3 0.012 15.8 0.3 2.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Laminin_II PF06009.12 EON98422.1 - 0.0028 17.7 1.6 0.0028 17.7 1.6 8.8 3 2 3 7 7 7 2 Laminin Domain II AAA_22 PF13401.6 EON98422.1 - 1.9 8.7 4.7 25 5.1 0.0 3.8 4 0 0 4 4 4 0 AAA domain ADH_N PF08240.12 EON98423.1 - 3.5e-28 97.7 0.4 9.1e-28 96.3 0.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON98423.1 - 2.9e-23 82.3 0.1 5.2e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EON98423.1 - 1.6e-06 27.8 0.1 3.2e-05 23.5 0.1 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EON98423.1 - 9.4e-06 26.7 0.0 6.8e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EON98423.1 - 0.0023 18.6 0.0 0.0051 17.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.19 EON98423.1 - 0.028 13.8 0.1 0.053 12.9 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 EON98424.1 - 8.4e-24 84.1 0.0 1.7e-23 83.1 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON98424.1 - 1.4e-16 60.8 0.0 1.9e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON98424.1 - 3.5e-09 36.8 0.0 4.8e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON98424.1 - 3.2e-06 26.8 0.0 4.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EON98424.1 - 7.1e-06 26.0 0.7 1.1e-05 25.5 0.7 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EON98424.1 - 2e-05 24.2 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sugar_tr PF00083.24 EON98425.1 - 1.1e-93 314.5 17.4 1.3e-93 314.4 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON98425.1 - 5.7e-17 61.7 27.7 5.7e-17 61.7 27.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gly-zipper_Omp PF13488.6 EON98425.1 - 0.71 9.9 3.3 0.3 11.1 0.4 1.9 2 0 0 2 2 2 0 Glycine zipper ADH_N PF08240.12 EON98426.1 - 9.7e-28 96.2 0.7 9.7e-28 96.2 0.7 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON98426.1 - 2.8e-16 59.7 0.0 4.2e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EON98426.1 - 7.4e-07 28.9 0.4 8.4e-06 25.4 0.4 2.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 EON98426.1 - 0.14 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Amidohydro_1 PF01979.20 EON98427.1 - 1e-14 54.7 0.0 2.9e-13 49.9 0.0 2.4 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 EON98427.1 - 5.6e-11 42.6 1.3 8e-05 22.3 0.2 3.1 1 1 1 2 2 2 2 Amidohydrolase family adh_short PF00106.25 EON98428.1 - 4.1e-41 140.6 5.6 4.6e-41 140.4 5.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON98428.1 - 9.1e-38 130.1 5.7 1.1e-37 129.9 5.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON98428.1 - 2.2e-14 53.7 2.2 3e-14 53.3 2.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON98428.1 - 0.022 14.2 1.4 0.19 11.2 1.4 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AIRC PF00731.20 EON98428.1 - 0.027 14.1 0.2 0.027 14.1 0.2 2.0 2 1 0 2 2 2 0 AIR carboxylase Glyco_trans_4_4 PF13579.6 EON98428.1 - 0.038 14.4 0.1 0.067 13.6 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain TilS PF09179.11 EON98429.1 - 0.047 14.2 1.0 0.3 11.6 0.1 2.5 3 0 0 3 3 3 0 TilS substrate binding domain DUF825 PF05695.12 EON98430.1 - 0.036 11.2 0.1 0.038 11.2 0.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) D5_N PF08706.11 EON98430.1 - 0.047 14.0 0.1 0.067 13.5 0.1 1.2 1 0 0 1 1 1 0 D5 N terminal like Wbp11 PF09429.10 EON98430.1 - 0.12 12.8 1.6 0.22 11.9 1.6 1.4 1 0 0 1 1 1 0 WW domain binding protein 11 adh_short_C2 PF13561.6 EON98431.1 - 1.3e-63 214.7 0.0 1.6e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON98431.1 - 2e-41 141.6 0.1 2.5e-41 141.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON98431.1 - 7.3e-14 52.1 0.1 9.8e-14 51.7 0.1 1.1 1 0 0 1 1 1 1 KR domain Glyco_hydro_99 PF16317.5 EON98431.1 - 0.041 13.0 0.1 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 99 Img2 PF05046.14 EON98433.1 - 1.2e-25 89.6 0.0 1.5e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) KAR9 PF08580.10 EON98433.1 - 3.4 6.1 6.3 3.8 6.0 6.3 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Aldo_ket_red PF00248.21 EON98434.1 - 5.7e-22 78.3 0.0 1.2e-21 77.2 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family AA_permease_2 PF13520.6 EON98435.1 - 2.3e-62 211.2 24.6 3.2e-62 210.7 24.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EON98435.1 - 1.2e-14 53.8 20.4 1.8e-14 53.2 20.4 1.2 1 0 0 1 1 1 1 Amino acid permease ARID PF01388.21 EON98436.1 - 9.7e-18 64.6 0.2 6.3e-17 62.0 0.0 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 EON98436.1 - 0.024 13.9 0.2 0.024 13.9 0.2 3.0 3 1 1 4 4 4 0 SWI/SNF-like complex subunit BAF250/Osa PACT_coil_coil PF10495.9 EON98436.1 - 9.9 6.8 12.6 4.9 7.8 0.0 3.9 4 0 0 4 4 4 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein His_Phos_2 PF00328.22 EON98437.1 - 6.1e-27 95.0 0.0 7.9e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_S8 PF00082.22 EON98438.1 - 8.5e-10 38.4 0.1 1.2e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EON98438.1 - 0.033 14.9 0.1 0.058 14.1 0.1 1.4 1 0 0 1 1 1 0 Peptidase inhibitor I9 Neprosin PF03080.15 EON98440.1 - 2.4e-48 164.4 13.5 3.4e-48 163.9 13.5 1.2 1 0 0 1 1 1 1 Neprosin HRXXH PF13933.6 EON98441.1 - 6.8e-70 235.4 0.1 7.9e-70 235.2 0.1 1.0 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 EON98441.1 - 4.5e-06 27.3 0.0 6.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Cellulase PF00150.18 EON98442.1 - 1.7e-20 73.6 2.4 3.2e-20 72.7 2.4 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) E1-E2_ATPase PF00122.20 EON98444.1 - 1.3e-48 164.9 5.4 1.3e-48 164.9 5.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EON98444.1 - 1.6e-20 74.3 0.1 3.2e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EON98444.1 - 0.00036 20.4 0.1 0.015 15.0 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EON98444.1 - 0.0028 18.0 0.7 0.015 15.7 0.1 2.5 2 0 0 2 2 2 1 Heavy-metal-associated domain EutQ PF06249.12 EON98446.1 - 1.8e-12 47.3 0.0 2.2e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 EON98446.1 - 1.6e-09 37.4 0.1 4.7e-09 35.8 0.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 EON98446.1 - 3.3e-05 23.5 0.0 4.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 EON98446.1 - 0.0087 15.8 0.0 0.01 15.6 0.0 1.1 1 0 0 1 1 1 1 Cupin Pirin PF02678.16 EON98446.1 - 0.026 14.5 0.0 0.076 13.0 0.0 1.6 1 1 0 2 2 2 0 Pirin Cupin_1 PF00190.22 EON98446.1 - 0.041 13.5 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.19 EON98446.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain KduI PF04962.12 EON98446.1 - 0.18 11.1 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family Methyltransf_23 PF13489.6 EON98447.1 - 7.8e-09 35.6 0.0 5.8e-06 26.2 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EON98447.1 - 7.1e-07 29.8 0.0 1.5e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON98447.1 - 8.3e-06 25.7 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EON98447.1 - 0.00039 19.9 0.0 0.00077 19.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EON98447.1 - 0.0014 18.2 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EON98447.1 - 0.0024 18.6 0.1 0.0051 17.5 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 EON98447.1 - 0.0038 17.0 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 EON98447.1 - 0.0041 17.7 0.0 0.012 16.2 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EON98447.1 - 0.02 14.3 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EON98447.1 - 0.036 14.2 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Crystallin PF00525.18 EON98447.1 - 0.081 13.1 0.0 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 Alpha crystallin A chain, N terminal Amidase PF01425.21 EON98448.1 - 2.8e-13 49.7 0.0 6e-13 48.6 0.0 1.5 1 1 0 1 1 1 1 Amidase Aldedh PF00171.22 EON98449.1 - 4.7e-119 397.9 0.0 5.4e-119 397.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EON98449.1 - 0.039 13.0 0.1 0.096 11.7 0.1 1.6 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) zf-C2H2_4 PF13894.6 EON98450.1 - 1.7 9.7 7.0 0.59 11.1 1.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 EON98450.1 - 2.8 8.6 8.0 8.3 7.1 0.8 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 EON98450.1 - 4.4 7.9 7.6 25 5.6 1.6 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type p450 PF00067.22 EON98451.1 - 2.1e-59 201.5 0.0 2.7e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1989 PF09347.10 EON98452.1 - 3.3e-52 176.5 0.0 5.7e-52 175.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.21 EON98452.1 - 2.7e-16 59.6 0.0 4.7e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EON98452.1 - 1.1e-06 28.5 0.0 2.1e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF3253 PF11625.8 EON98452.1 - 0.2 11.9 0.0 0.57 10.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) La_HTH_kDCL PF18177.1 EON98452.1 - 0.22 11.9 0.9 0.49 10.7 0.2 1.9 2 0 0 2 2 2 0 La HTH in kinetoplastid DICER domain DUF2194 PF09960.9 EON98452.1 - 0.23 9.8 0.0 0.31 9.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) MFS_1 PF07690.16 EON98453.1 - 2.7e-37 128.5 26.0 2.7e-37 128.5 26.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON98453.1 - 3.3e-09 36.1 31.3 4e-08 32.5 30.6 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter DUF2417 PF10329.9 EON98453.1 - 0.069 12.6 2.2 1.2 8.5 0.9 2.7 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Neurokinin_B PF03823.14 EON98453.1 - 0.18 11.9 0.8 16 5.6 0.0 2.4 2 0 0 2 2 2 0 Neurokinin B DEAD PF00270.29 EON98454.1 - 4.9e-43 146.9 0.0 7.1e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON98454.1 - 9.7e-28 96.7 0.9 7e-27 94.0 0.3 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON98454.1 - 0.00075 19.5 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EON98454.1 - 0.096 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit NAD_binding_4 PF07993.12 EON98455.1 - 2.7e-31 108.7 0.0 4.2e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EON98455.1 - 2.2e-15 56.2 0.0 4.4e-15 55.2 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EON98455.1 - 3e-12 46.5 0.0 7.3e-12 45.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EON98455.1 - 1.3e-07 31.9 0.0 3.8e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 EON98455.1 - 8.6e-07 28.7 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EON98455.1 - 0.0038 17.2 0.2 0.024 14.6 0.0 2.5 3 1 0 3 3 3 1 KR domain RmlD_sub_bind PF04321.17 EON98455.1 - 0.0055 15.8 0.0 0.16 11.0 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain Semialdhyde_dh PF01118.24 EON98455.1 - 0.16 12.4 0.0 0.51 10.8 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Peptidase_M20 PF01546.28 EON98456.1 - 1.5e-21 77.0 0.1 2.4e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EON98456.1 - 1.6e-05 24.8 0.0 3.9e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EON98456.1 - 0.00097 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Mqo PF06039.15 EON98456.1 - 0.061 11.9 0.2 0.28 9.7 0.0 1.8 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) TerB_C PF15615.6 EON98456.1 - 0.15 12.3 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 TerB-C domain Ribosomal_S10 PF00338.22 EON98457.1 - 1.1e-26 92.8 0.2 1.4e-26 92.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Fibrillarin_2 PF10113.9 EON98457.1 - 0.0073 15.0 0.1 0.0074 15.0 0.1 1.1 1 0 0 1 1 1 1 Fibrillarin-like archaeal protein SnoaL_2 PF12680.7 EON98458.1 - 0.0001 22.9 0.0 0.00017 22.1 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EON98458.1 - 0.00057 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase ATG16 PF08614.11 EON98459.1 - 0.00047 20.5 47.9 0.0093 16.2 1.8 5.8 3 2 2 5 5 5 3 Autophagy protein 16 (ATG16) BRE1 PF08647.11 EON98459.1 - 0.00047 20.2 1.1 0.00047 20.2 1.1 5.6 3 1 1 5 5 5 1 BRE1 E3 ubiquitin ligase HIP1_clath_bdg PF16515.5 EON98459.1 - 0.00052 20.6 4.8 0.00052 20.6 4.8 5.8 4 1 2 6 6 6 2 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_13 PF13166.6 EON98459.1 - 0.00093 18.0 33.7 0.021 13.5 0.4 4.0 3 1 0 4 4 4 3 AAA domain Nsp1_C PF05064.13 EON98459.1 - 0.0067 16.2 4.0 0.0067 16.2 4.0 4.4 5 1 0 5 5 4 1 Nsp1-like C-terminal region ADIP PF11559.8 EON98459.1 - 0.012 15.8 0.2 0.012 15.8 0.2 5.3 3 2 2 5 5 5 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 EON98459.1 - 0.063 12.2 38.2 0.09 11.6 4.6 4.2 3 1 1 4 4 4 0 Spc7 kinetochore protein DUF641 PF04859.12 EON98459.1 - 0.067 13.5 29.9 0.32 11.3 2.1 5.7 3 1 2 5 5 5 0 Plant protein of unknown function (DUF641) BicD PF09730.9 EON98459.1 - 0.098 11.1 32.3 0.0061 15.0 7.7 4.2 3 1 2 5 5 5 0 Microtubule-associated protein Bicaudal-D Fez1 PF06818.15 EON98459.1 - 0.16 12.4 33.2 3.3 8.1 1.8 4.3 3 1 0 3 3 3 0 Fez1 SlyX PF04102.12 EON98459.1 - 0.16 12.6 32.3 0.28 11.8 0.1 7.0 5 3 3 8 8 8 0 SlyX Serine_rich PF08824.10 EON98459.1 - 0.17 11.9 18.9 0.32 11.0 1.0 3.8 3 1 0 3 3 3 0 Serine rich protein interaction domain MPS2 PF17060.5 EON98459.1 - 0.27 10.4 14.5 1.4 8.1 7.1 2.9 2 1 1 3 3 3 0 Monopolar spindle protein 2 UPF0242 PF06785.11 EON98459.1 - 0.42 10.7 35.0 0.37 10.9 3.4 4.7 3 1 2 5 5 5 0 Uncharacterised protein family (UPF0242) N-terminus Filament PF00038.21 EON98459.1 - 0.44 10.1 36.7 0.82 9.2 18.6 4.6 3 1 0 3 3 3 0 Intermediate filament protein HMMR_N PF15905.5 EON98459.1 - 0.51 9.7 32.9 0.81 9.1 1.8 3.8 3 1 1 4 4 4 0 Hyaluronan mediated motility receptor N-terminal DUF2730 PF10805.8 EON98459.1 - 1.5 9.0 15.4 0.79 9.8 0.1 5.3 3 2 2 5 5 5 0 Protein of unknown function (DUF2730) TMF_TATA_bd PF12325.8 EON98459.1 - 1.5 9.0 34.9 3.8 7.8 0.6 6.1 3 1 2 5 5 5 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 EON98459.1 - 1.7 8.7 24.0 0.28 11.2 0.1 5.4 4 1 2 6 6 6 0 Protein of unknown function (DUF1664) IFT46_B_C PF12317.8 EON98459.1 - 2 8.1 4.8 5.5 6.7 0.1 3.1 3 1 0 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal TACC_C PF05010.14 EON98459.1 - 2.3 8.0 31.7 0.3 10.9 12.0 4.7 3 1 2 5 5 5 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal MscS_porin PF12795.7 EON98459.1 - 2.4 7.7 35.2 0.26 10.8 8.6 4.7 2 2 0 3 3 3 0 Mechanosensitive ion channel porin domain DUF1192 PF06698.11 EON98459.1 - 2.4 8.3 25.6 7.9 6.6 0.3 6.8 6 1 1 7 7 7 0 Protein of unknown function (DUF1192) APG6_N PF17675.1 EON98459.1 - 2.6 8.6 39.5 2.5 8.6 0.1 5.4 3 1 2 5 5 5 0 Apg6 coiled-coil region COX16 PF14138.6 EON98459.1 - 5 7.7 6.5 3.5 8.2 0.2 3.4 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 DUF4407 PF14362.6 EON98459.1 - 9.2 5.5 35.2 0.56 9.5 2.1 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Iso_dh PF00180.20 EON98460.1 - 1.8e-102 343.1 0.0 2.2e-102 342.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DIOX_N PF14226.6 EON98461.1 - 6.9e-16 59.1 0.1 7.7e-16 58.9 0.1 1.0 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal U3_assoc_6 PF08640.11 EON98463.1 - 2.5e-26 91.5 2.3 1.2e-25 89.4 0.4 2.7 2 1 1 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 EON98463.1 - 1.9e-05 25.1 1.2 0.0098 16.6 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.10 EON98463.1 - 0.0008 18.6 0.1 0.002 17.3 0.0 1.7 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference CENP-B_dimeris PF09026.10 EON98463.1 - 0.25 11.7 5.4 0.5 10.8 5.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 EON98463.1 - 0.43 11.0 3.7 1 9.8 3.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ferritin_2 PF13668.6 EON98464.1 - 7.6e-42 142.7 3.8 1.2e-41 142.1 3.8 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF455 PF04305.14 EON98464.1 - 0.031 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF455) NACHT PF05729.12 EON98465.1 - 9.6e-09 35.4 1.4 4e-07 30.1 0.2 3.2 3 1 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 EON98465.1 - 7.8e-06 26.4 2.8 1.7e-05 25.3 0.0 2.8 3 1 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 EON98465.1 - 0.0011 19.5 0.0 0.0033 17.9 0.0 1.9 1 0 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 EON98465.1 - 0.0012 19.2 0.1 0.0064 16.9 0.1 2.2 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.6 EON98465.1 - 0.0046 16.7 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EON98465.1 - 0.0059 16.9 0.2 0.033 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EON98465.1 - 0.014 15.6 0.0 0.05 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EON98465.1 - 0.015 15.8 0.0 0.057 14.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EON98465.1 - 0.016 15.3 0.0 0.058 13.5 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase TetR_C_36 PF18598.1 EON98465.1 - 0.017 15.1 0.4 0.83 9.6 0.0 2.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AAA_30 PF13604.6 EON98465.1 - 0.024 14.3 0.5 0.073 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EON98465.1 - 0.036 13.7 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ploopntkinase3 PF18751.1 EON98465.1 - 0.053 13.4 0.2 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA PF00004.29 EON98465.1 - 0.062 13.7 0.1 0.6 10.5 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EON98465.1 - 0.063 13.2 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 EON98465.1 - 0.066 12.9 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EON98465.1 - 0.07 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 EON98465.1 - 0.089 12.4 2.1 3.8 7.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 EON98465.1 - 0.14 12.7 0.0 0.14 12.7 0.0 2.3 3 0 0 3 3 2 0 AAA domain dCMP_cyt_deam_1 PF00383.23 EON98466.1 - 1.6e-09 37.5 0.1 2.1e-09 37.2 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EON98466.1 - 4.9e-09 36.1 0.0 6.1e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Methyltransf_23 PF13489.6 EON98467.1 - 1.3e-09 38.1 0.0 3.5e-06 27.0 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EON98467.1 - 1.3e-06 29.0 0.0 7.3e-06 26.6 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON98467.1 - 4.4e-05 24.1 0.0 0.0032 18.1 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON98467.1 - 0.00023 20.6 0.0 0.0058 16.0 0.0 2.2 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EON98467.1 - 0.0033 18.2 0.0 0.017 15.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 EON98467.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PTSIIA_gutA PF03829.13 EON98467.1 - 0.023 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 PTS system glucitol/sorbitol-specific IIA component Methyltransf_31 PF13847.6 EON98467.1 - 0.12 12.1 0.0 0.83 9.4 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain FAD_binding_3 PF01494.19 EON98468.1 - 5.6e-11 42.3 3.9 5.6e-09 35.7 0.5 2.7 2 1 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.24 EON98468.1 - 0.0024 17.2 0.1 0.0041 16.5 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EON98468.1 - 0.016 14.3 1.1 2.4 7.1 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox PF00070.27 EON98468.1 - 1.3 9.7 5.6 6.8 7.3 0.3 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EON98469.1 - 2.2e-53 181.7 0.3 8.3e-52 176.6 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EON98469.1 - 3.6e-07 30.4 0.0 1.3e-06 28.5 0.0 1.9 1 1 1 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.17 EON98469.1 - 2.1e-05 23.9 0.1 3.4e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EON98469.1 - 3.5e-05 23.6 0.2 8.5e-05 22.3 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON98469.1 - 9.6e-05 21.7 0.2 0.00044 19.6 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON98469.1 - 0.0001 22.5 0.0 0.00037 20.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EON98469.1 - 0.00019 21.9 0.0 0.00045 20.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON98469.1 - 0.00045 19.0 0.0 0.00077 18.3 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 EON98469.1 - 0.00083 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EON98469.1 - 0.00092 18.4 0.0 0.0026 16.9 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EON98469.1 - 0.001 18.4 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON98469.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EON98469.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EON98469.1 - 0.021 15.2 0.0 0.045 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EON98469.1 - 0.022 14.1 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EON98469.1 - 0.15 12.4 0.0 0.57 10.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain eIF3_N PF09440.10 EON98471.1 - 7.4e-51 172.1 0.4 1.6e-49 167.8 2.7 2.0 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EON98471.1 - 1.6e-13 51.1 0.0 6e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 PCI domain FAD_binding_3 PF01494.19 EON98472.1 - 1.3e-18 67.3 0.0 2.6e-18 66.4 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EON98472.1 - 9.4e-11 41.5 0.1 2.4e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON98472.1 - 5.5e-09 35.6 0.3 1.2e-08 34.4 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EON98472.1 - 9.4e-09 34.5 0.1 1.5e-05 23.9 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 EON98472.1 - 2.3e-08 34.0 0.6 0.00036 20.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EON98472.1 - 4e-06 26.5 0.2 8e-06 25.5 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EON98472.1 - 1.1e-05 25.5 0.1 3.7e-05 23.9 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EON98472.1 - 1.2e-05 25.8 0.2 0.008 16.7 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON98472.1 - 2.1e-05 24.0 0.0 0.0023 17.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON98472.1 - 2.9e-05 23.3 0.0 4.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 EON98472.1 - 0.00012 21.1 0.1 0.29 9.9 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 EON98472.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EON98472.1 - 0.023 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EON98472.1 - 0.039 13.0 0.1 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 EON98472.1 - 0.11 11.8 0.1 3 7.0 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Aldedh PF00171.22 EON98473.1 - 1.6e-118 396.2 3.6 9.7e-79 265.0 1.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 EON98473.1 - 0.0023 17.0 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) CUE PF02845.16 EON98474.1 - 2.9e-10 39.6 0.1 5.4e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 CUE domain NOA36 PF06524.12 EON98474.1 - 0.16 11.2 2.5 0.27 10.5 2.5 1.2 1 0 0 1 1 1 0 NOA36 protein BTB PF00651.31 EON98475.1 - 1.2e-05 25.5 0.0 2.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain FMN_dh PF01070.18 EON98476.1 - 6e-67 226.1 0.1 6.8e-67 226.0 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EON98476.1 - 1.2e-06 27.8 1.6 3.7e-05 22.9 0.5 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EON98476.1 - 2.7e-05 23.5 0.1 4.1e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 EON98476.1 - 0.00022 20.7 0.3 0.00034 20.1 0.3 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 EON98476.1 - 0.029 13.9 0.1 0.079 12.4 0.1 1.6 1 1 1 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 EON98476.1 - 0.06 12.6 0.1 0.46 9.8 0.2 2.1 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Glyco_hydro_18 PF00704.28 EON98477.1 - 1.2e-64 219.1 1.4 1.8e-64 218.4 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 NmrA PF05368.13 EON98478.1 - 2.8e-16 59.8 0.0 3.4e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EON98478.1 - 3.4e-11 43.4 0.0 6.3e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EON98478.1 - 0.00075 19.0 0.0 0.018 14.5 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EON98478.1 - 0.054 13.9 0.1 0.098 13.1 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.16 EON98479.1 - 3.5e-27 95.3 35.7 6.6e-27 94.3 35.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EON98479.1 - 8.8e-06 25.2 9.7 8.8e-06 25.2 9.7 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4131 PF13567.6 EON98479.1 - 2.1 8.0 8.2 9.6 5.8 1.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF3176 PF11374.8 EON98480.1 - 7.1e-30 103.4 1.7 7.1e-30 103.4 1.7 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) MARVEL PF01284.23 EON98480.1 - 1.1 9.3 7.8 1.4 9.0 3.5 2.4 2 0 0 2 2 2 0 Membrane-associating domain zf-CCCH_4 PF18044.1 EON98481.1 - 0.0012 18.6 2.1 0.0022 17.8 2.1 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EON98481.1 - 0.046 13.8 5.9 0.1 12.7 5.9 1.6 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 EON98481.1 - 0.046 13.6 0.9 0.046 13.6 0.9 1.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DnaJ PF00226.31 EON98482.1 - 1.6e-07 31.4 1.3 2.9e-07 30.5 1.3 1.5 1 0 0 1 1 1 1 DnaJ domain MFS_1 PF07690.16 EON98483.1 - 9.9e-23 80.6 9.7 1.2e-22 80.3 9.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON98483.1 - 3.9e-10 39.2 8.0 3.9e-10 39.2 8.0 1.9 1 1 0 2 2 2 1 Sugar (and other) transporter DUF3784 PF12650.7 EON98483.1 - 0.042 14.1 1.5 0.042 14.1 1.5 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) Wzy_C PF04932.15 EON98483.1 - 0.077 12.6 0.2 0.077 12.6 0.2 2.0 2 1 0 2 2 2 0 O-Antigen ligase DUF1772 PF08592.11 EON98483.1 - 0.4 11.0 0.0 0.4 11.0 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Frag1 PF10277.9 EON98484.1 - 4.4e-37 127.7 12.8 4.4e-37 127.7 12.8 2.9 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 EON98484.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF996 PF06195.13 EON98484.1 - 1.6 9.0 5.9 0.51 10.6 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF996) adh_short PF00106.25 EON98485.1 - 1e-21 77.3 0.8 1.3e-21 77.0 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON98485.1 - 6.7e-20 71.6 0.5 8.3e-20 71.3 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON98485.1 - 2.2e-07 31.0 0.2 2.8e-07 30.6 0.2 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EON98485.1 - 0.013 15.4 0.4 0.017 15.0 0.4 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ChuX_HutX PF06228.13 EON98485.1 - 0.033 14.0 0.1 0.08 12.7 0.0 1.6 1 1 1 2 2 2 0 Haem utilisation ChuX/HutX THF_DHG_CYH_C PF02882.19 EON98485.1 - 0.039 13.3 0.4 0.053 12.8 0.4 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UDPG_MGDP_dh_N PF03721.14 EON98485.1 - 0.04 13.5 0.1 0.048 13.2 0.1 1.1 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain EVE PF01878.18 EON98486.1 - 1.8e-46 157.7 0.7 2.3e-46 157.4 0.0 1.5 2 0 0 2 2 2 1 EVE domain DUF3292 PF11696.8 EON98486.1 - 0.015 13.7 5.0 0.02 13.3 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Mitofilin PF09731.9 EON98486.1 - 1.9 7.2 12.6 2.3 7.0 12.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Methyltransf_2 PF00891.18 EON98487.1 - 1.2e-12 47.6 0.0 1.9e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EON98487.1 - 0.037 13.9 0.0 0.15 11.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Glyco_hydro_61 PF03443.14 EON98488.1 - 8.2e-55 185.9 0.5 1.2e-54 185.4 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.25 EON98488.1 - 1.8e-15 56.9 0.2 8.6e-13 48.2 0.3 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 EON98488.1 - 2.5e-08 34.1 0.1 4.1e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EON98488.1 - 2.1e-06 27.5 0.2 4.1e-05 23.3 0.6 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.20 EON98488.1 - 0.0052 16.9 0.1 0.0091 16.1 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EON98488.1 - 0.0064 17.1 0.3 0.012 16.2 0.3 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 EON98488.1 - 0.017 14.3 0.2 0.023 13.8 0.2 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Arg_repressor_C PF02863.18 EON98488.1 - 0.022 14.6 0.2 0.05 13.5 0.2 1.6 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain GDP_Man_Dehyd PF16363.5 EON98488.1 - 0.041 13.3 0.0 0.055 12.9 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EON98488.1 - 0.068 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_trans_4_4 PF13579.6 EON98488.1 - 0.14 12.6 0.4 22 5.5 0.2 2.3 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain DUF2754 PF10953.8 EON98489.1 - 0.13 12.5 0.1 0.34 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) VPS13_C PF16909.5 EON98490.1 - 0.00051 19.9 0.3 0.0059 16.4 0.2 2.2 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal Aldedh PF00171.22 EON98491.1 - 4.9e-86 289.1 0.1 6.1e-86 288.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 EON98491.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 WTAP/Mum2p family OmdA PF13376.6 EON98491.1 - 0.064 13.3 0.3 0.43 10.6 0.2 2.3 1 1 1 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF3328 PF11807.8 EON98492.1 - 6.2e-20 71.9 3.2 6.8e-20 71.8 1.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) CTNNBL PF08216.11 EON98493.1 - 3.8e-39 133.0 0.0 1.8e-38 130.9 0.0 2.2 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear DUF3361 PF11841.8 EON98493.1 - 0.0008 19.4 0.4 0.066 13.1 0.4 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3361) HEAT_2 PF13646.6 EON98493.1 - 0.022 15.1 0.9 3.6 8.1 0.1 2.9 2 0 0 2 2 2 0 HEAT repeats Mo25 PF08569.11 EON98493.1 - 0.074 12.4 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Mo25-like Atx10homo_assoc PF09759.9 EON98493.1 - 0.078 13.0 0.3 0.26 11.3 0.3 1.9 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain SEN1_N PF12726.7 EON98493.1 - 0.081 11.1 0.3 0.81 7.8 0.0 2.1 1 1 1 2 2 2 0 SEN1 N terminal RPAP1_N PF08621.10 EON98493.1 - 0.09 12.6 0.5 11 5.9 0.1 3.0 2 0 0 2 2 2 0 RPAP1-like, N-terminal IDO PF01231.18 EON98494.1 - 9.4e-110 367.4 0.0 1.2e-109 367.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase MFS_1 PF07690.16 EON98495.1 - 1e-26 93.7 57.6 4.2e-25 88.4 33.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PIG-P PF08510.12 EON98495.1 - 0.23 11.4 7.2 1.8 8.5 0.0 3.6 4 0 0 4 4 4 0 PIG-P Cu_amine_oxid PF01179.20 EON98496.1 - 1.5e-66 225.0 6.0 1e-48 166.3 0.2 3.1 1 1 2 3 3 3 3 Copper amine oxidase, enzyme domain STE2 PF02116.15 EON98497.1 - 9.3e-78 261.4 23.8 1.1e-77 261.2 23.8 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR GTP_EFTU PF00009.27 EON98498.1 - 5.5e-50 169.6 0.0 8.8e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EON98498.1 - 3.2e-42 143.0 3.8 5.5e-42 142.3 3.8 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EON98498.1 - 1.2e-18 66.9 0.0 2.5e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EON98498.1 - 5.3e-07 29.9 0.1 1.1e-06 28.9 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EON98498.1 - 2.9e-05 24.1 0.0 7.7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EON98498.1 - 0.00017 21.2 0.0 0.0005 19.7 0.0 1.8 2 0 0 2 2 2 1 Ras family SRPRB PF09439.10 EON98498.1 - 0.0019 17.6 0.1 0.0089 15.5 0.0 2.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Snurportin1 PF11538.8 EON98498.1 - 0.32 11.2 2.5 0.64 10.2 2.5 1.5 1 0 0 1 1 1 0 Snurportin1 MFS_1 PF07690.16 EON98499.1 - 3.8e-07 29.4 37.9 1.9e-05 23.8 33.6 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EON98499.1 - 1.4e-05 23.7 15.0 1.8e-05 23.4 15.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) S1FA PF04689.13 EON98499.1 - 3.1 8.0 4.3 0.93 9.7 0.2 2.3 2 0 0 2 2 2 0 DNA binding protein S1FA ABC_membrane PF00664.23 EON98500.1 - 7.1e-84 281.7 26.1 1.2e-45 156.3 2.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EON98500.1 - 2.4e-66 222.4 0.0 1.3e-31 110.0 0.0 2.6 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EON98500.1 - 5.1e-10 39.2 1.8 0.0016 17.9 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EON98500.1 - 2.2e-08 33.7 0.1 0.0063 16.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EON98500.1 - 6.1e-08 33.2 2.7 0.009 16.4 1.2 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EON98500.1 - 7.5e-07 29.5 0.0 0.18 12.0 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.6 EON98500.1 - 7.9e-06 26.5 2.8 0.17 12.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 EON98500.1 - 1.3e-05 25.0 1.0 0.092 12.5 0.0 3.4 3 1 0 3 3 3 2 AAA domain DUF3987 PF13148.6 EON98500.1 - 3.2e-05 23.1 4.9 0.0049 15.9 0.0 2.9 3 0 0 3 3 2 2 Protein of unknown function (DUF3987) RsgA_GTPase PF03193.16 EON98500.1 - 6.5e-05 22.9 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EON98500.1 - 8.7e-05 22.5 0.5 0.89 9.3 0.0 3.8 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 EON98500.1 - 0.00012 21.4 0.0 0.33 10.2 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin G-alpha PF00503.20 EON98500.1 - 0.0002 20.6 0.0 0.18 10.9 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit ABC_ATPase PF09818.9 EON98500.1 - 0.00029 19.8 1.3 0.013 14.3 0.0 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_33 PF13671.6 EON98500.1 - 0.00037 20.7 0.0 1.5 8.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 EON98500.1 - 0.00065 19.9 2.4 0.57 10.2 0.0 3.3 3 0 0 3 3 3 1 Helicase HerA, central domain APS_kinase PF01583.20 EON98500.1 - 0.00092 19.1 0.1 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_18 PF13238.6 EON98500.1 - 0.001 19.6 0.0 1.8 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EON98500.1 - 0.0015 18.5 0.0 6.7 6.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 EON98500.1 - 0.0016 18.6 0.3 5.4 7.3 0.2 3.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 EON98500.1 - 0.0062 16.6 0.6 2.4 8.3 0.1 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_17 PF13207.6 EON98500.1 - 0.01 16.2 0.1 5.7 7.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EON98500.1 - 0.011 15.3 0.1 5.6 6.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 EON98500.1 - 0.017 14.3 0.0 3.8 6.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 EON98500.1 - 0.022 15.2 0.1 82 3.6 0.0 4.4 5 0 0 5 5 3 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EON98500.1 - 0.024 14.3 0.2 3.6 7.2 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_24 PF13479.6 EON98500.1 - 0.037 13.8 0.0 8.7 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EON98500.1 - 0.066 12.8 0.1 0.94 9.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.17 EON98500.1 - 0.094 12.4 0.0 15 5.2 0.0 2.9 3 0 0 3 3 2 0 Thymidylate kinase PRK PF00485.18 EON98500.1 - 0.1 12.3 0.7 7.3 6.3 0.0 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 EON98500.1 - 0.16 12.4 0.0 10 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Sugar_tr PF00083.24 EON98501.1 - 1.5e-35 122.9 11.5 1.8e-35 122.7 11.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON98501.1 - 1.2e-08 34.3 12.8 1.5e-08 33.9 12.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.25 EON98502.1 - 1.1e-25 90.2 0.1 1.4e-25 89.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON98502.1 - 7.1e-17 61.7 0.1 8.5e-17 61.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON98502.1 - 5.2e-08 33.0 0.1 9.2e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON98502.1 - 5.5e-06 26.0 0.3 3.8e-05 23.3 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EON98502.1 - 0.00089 19.2 0.2 0.0023 17.8 0.2 1.7 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EON98502.1 - 0.086 12.2 2.5 0.13 11.6 0.1 2.0 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase GST_C_2 PF13410.6 EON98503.1 - 4.3e-14 52.3 0.1 1.2e-13 50.8 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EON98503.1 - 6.8e-12 45.5 0.0 1.6e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EON98503.1 - 2.5e-06 27.6 0.0 4.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EON98503.1 - 7.8e-06 26.0 0.3 5.6e-05 23.3 0.2 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EON98503.1 - 0.047 13.5 0.1 0.076 12.8 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cupin_2 PF07883.11 EON98504.1 - 3.8e-18 65.0 0.1 1.4e-14 53.5 0.0 2.5 2 0 0 2 2 2 2 Cupin domain FAD_binding_3 PF01494.19 EON98504.1 - 2.1e-12 47.0 0.0 1.6e-09 37.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Cupin_3 PF05899.12 EON98504.1 - 0.018 14.7 0.0 5.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) CENP-C_C PF11699.8 EON98504.1 - 0.11 12.8 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 Mif2/CENP-C like Sugar_tr PF00083.24 EON98505.1 - 3.9e-88 296.3 20.1 4.5e-88 296.1 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON98505.1 - 3.2e-18 65.8 26.4 5.1e-18 65.1 20.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EON98505.1 - 1.2e-05 24.1 22.2 0.002 16.8 6.3 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Folate_carrier PF01770.18 EON98505.1 - 0.0031 16.3 2.5 0.0061 15.4 2.5 1.4 1 1 0 1 1 1 1 Reduced folate carrier Acetyltransf_3 PF13302.7 EON98506.1 - 1e-23 84.5 0.0 8.1e-23 81.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON98506.1 - 6.8e-06 26.3 0.0 8.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EON98506.1 - 0.0025 17.5 0.0 0.0061 16.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Abhydrolase_3 PF07859.13 EON98507.1 - 4.6e-23 82.2 0.0 6.7e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EON98507.1 - 5.3e-19 68.5 0.1 2e-18 66.6 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EON98507.1 - 0.0044 16.5 0.9 0.015 14.8 0.9 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 EON98507.1 - 0.044 12.6 0.0 0.24 10.2 0.0 1.9 1 1 0 1 1 1 0 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 EON98507.1 - 0.086 13.4 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_61 PF03443.14 EON98508.1 - 3.2e-58 197.1 0.9 3.6e-58 196.9 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Hydrolase_6 PF13344.6 EON98509.1 - 6.5e-23 80.8 0.0 1.5e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EON98509.1 - 1.3e-19 70.0 0.0 3.4e-19 68.7 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EON98509.1 - 0.011 16.1 0.1 1.2 9.3 0.0 2.9 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EON98509.1 - 0.025 14.7 0.0 0.27 11.3 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EON98509.1 - 0.07 12.7 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase DUF4483 PF14825.6 EON98509.1 - 0.19 11.5 0.0 5.4 6.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4483) Aldo_ket_red PF00248.21 EON98510.1 - 6.5e-52 176.5 0.0 2e-51 175.0 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family HTH_24 PF13412.6 EON98510.1 - 0.083 12.5 0.0 0.5 10.0 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Ribonuc_L-PSP PF01042.21 EON98511.1 - 1.5e-20 73.4 0.0 1.9e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.16 EON98512.1 - 3e-19 69.1 28.0 5.2e-18 65.1 15.5 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Beta-lactamase PF00144.24 EON98513.1 - 2.9e-46 158.2 0.0 4.1e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 EON98513.1 - 1.4e-05 24.8 0.0 0.1 12.2 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 EON98513.1 - 0.0054 16.2 0.0 0.0087 15.5 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase ADH_zinc_N PF00107.26 EON98514.1 - 2.7e-24 85.6 0.1 4.3e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON98514.1 - 2.2e-16 61.1 0.1 4.5e-16 60.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON98514.1 - 1.3e-09 37.9 0.0 1.2e-08 34.8 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Cupin_2 PF07883.11 EON98514.1 - 0.084 12.6 1.1 18 5.1 0.0 3.5 4 0 0 4 4 4 0 Cupin domain Peptidase_M50B PF13398.6 EON98515.1 - 3.2e-59 199.9 16.2 4.4e-59 199.5 16.2 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 EON98515.1 - 0.0084 15.4 0.2 0.018 14.4 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M50 Peptidase_M36 PF02128.15 EON98515.1 - 0.24 10.5 0.1 0.34 10.0 0.1 1.1 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) Alpha-amylase PF00128.24 EON98516.1 - 4.3e-111 371.7 0.0 6.4e-111 371.1 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 EON98516.1 - 0.0084 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Sugar_tr PF00083.24 EON98517.1 - 2.1e-77 260.9 23.1 8.1e-47 160.1 9.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EON98517.1 - 7.6e-09 34.9 11.4 7.6e-09 34.9 11.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-LITAF-like PF10601.9 EON98517.1 - 0.59 10.4 1.6 3.6 7.9 0.7 2.7 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Cu-oxidase PF00394.22 EON98518.1 - 5.8e-38 130.5 2.6 2.9e-35 121.7 0.5 3.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EON98518.1 - 1e-35 122.5 0.4 7.4e-33 113.2 0.1 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EON98518.1 - 7.4e-20 71.1 2.3 2.1e-18 66.4 0.1 3.2 3 0 0 3 3 3 1 Multicopper oxidase Myco_19_kDa PF05481.12 EON98518.1 - 0.27 11.5 1.3 1.1 9.5 0.7 2.3 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen PQQ PF01011.21 EON98518.1 - 3.9 7.6 6.4 27 4.9 0.0 4.1 4 0 0 4 4 4 0 PQQ enzyme repeat V-ATPase_G PF03179.15 EON98519.1 - 1e-33 116.0 18.7 1.2e-33 115.8 18.7 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 EON98519.1 - 0.0066 15.9 11.4 0.0066 15.9 11.4 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) V-ATPase_G_2 PF16999.5 EON98519.1 - 0.017 15.5 15.9 0.024 15.0 15.9 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 EON98519.1 - 0.018 15.2 10.1 0.018 15.2 10.1 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) ATP11 PF06644.11 EON98519.1 - 0.074 12.8 10.8 0.096 12.5 10.8 1.1 1 0 0 1 1 1 0 ATP11 protein DUF2203 PF09969.9 EON98519.1 - 0.16 12.7 5.9 0.21 12.3 5.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) RRF PF01765.19 EON98519.1 - 0.16 11.9 15.8 0.25 11.3 15.8 1.3 1 0 0 1 1 1 0 Ribosome recycling factor YusW PF14039.6 EON98519.1 - 0.29 11.7 8.2 0.33 11.5 7.5 1.4 1 1 0 1 1 1 0 YusW-like protein OmpH PF03938.14 EON98519.1 - 0.68 10.3 15.5 0.88 9.9 15.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4666 PF15697.5 EON98519.1 - 1.2 9.8 5.3 14 6.4 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4666) DUF4375 PF14300.6 EON98519.1 - 1.3 9.3 7.3 1.9 8.8 6.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4375) CemA PF03040.14 EON98519.1 - 2.1 8.2 4.8 2.7 7.9 4.8 1.3 1 0 0 1 1 1 0 CemA family AAA_11 PF13086.6 EON98519.1 - 3.9 7.2 10.5 4.9 6.9 10.5 1.1 1 0 0 1 1 1 0 AAA domain SAPS PF04499.15 EON98519.1 - 4.1 6.1 8.7 4.6 5.9 8.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ELH PF02323.15 EON98520.1 - 0.036 13.4 5.6 0.048 13.0 5.6 1.2 1 0 0 1 1 1 0 Egg-laying hormone precursor ICL PF00463.21 EON98521.1 - 5.1e-93 312.3 0.1 6e-93 312.1 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family DSBA PF01323.20 EON98522.1 - 9.2e-36 123.4 0.0 1e-35 123.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 EON98522.1 - 0.023 14.7 0.1 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain Replic_Relax PF13814.6 EON98522.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Replication-relaxation Thioredoxin_4 PF13462.6 EON98522.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 2 1 0 2 2 2 0 Thioredoxin LEA_5 PF00477.17 EON98522.1 - 0.15 12.5 3.2 3.6 8.1 0.4 2.4 2 0 0 2 2 2 0 Small hydrophilic plant seed protein CcmH PF03918.14 EON98522.1 - 0.16 11.3 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein RNA_pol_Rpb2_6 PF00562.28 EON98523.1 - 5.2e-125 417.6 0.1 8.5e-125 416.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EON98523.1 - 6.9e-54 182.5 0.0 2.4e-53 180.7 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EON98523.1 - 3.7e-48 163.7 0.1 7.6e-48 162.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EON98523.1 - 8.3e-33 112.7 0.1 2e-32 111.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EON98523.1 - 2e-25 88.7 0.1 4.9e-25 87.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EON98523.1 - 1e-23 83.6 0.9 3.1e-23 82.1 0.9 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 EON98523.1 - 2.6e-23 82.1 1.0 5.3e-23 81.1 0.3 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 SBF2 PF12335.8 EON98523.1 - 0.07 12.7 0.4 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 Myotubularin protein adh_short PF00106.25 EON98524.1 - 1.1e-18 67.4 0.3 1.1e-16 60.9 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON98524.1 - 2.1e-07 30.8 0.0 3e-07 30.2 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON98524.1 - 2e-06 27.9 0.1 3e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON98524.1 - 0.1 12.1 0.0 0.26 10.7 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EON98524.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_hydro_36 PF17167.4 EON98525.1 - 9.9e-46 156.3 0.0 2.9e-45 154.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_transf_36 PF06165.11 EON98525.1 - 4.2e-24 85.3 0.0 6.6e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 36 Bac_rhamnosid6H PF17389.2 EON98525.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.4 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF1479 PF07350.12 EON98526.1 - 1.6e-158 527.9 0.0 1.9e-158 527.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Reprolysin_4 PF13583.6 EON98527.1 - 8.4e-05 22.3 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EON98527.1 - 0.0021 18.2 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.8 EON98527.1 - 0.0073 15.9 1.4 0.4 10.2 1.4 2.2 1 1 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_3 PF13582.6 EON98527.1 - 0.014 15.9 0.0 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EON98527.1 - 0.036 13.0 0.8 0.072 12.0 0.6 1.5 1 1 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 EON98527.1 - 0.042 13.7 1.5 0.082 12.8 1.0 1.5 1 1 0 1 1 1 0 Matrixin Astacin PF01400.24 EON98527.1 - 0.15 11.6 0.4 0.23 11.0 0.4 1.4 1 1 0 1 1 1 0 Astacin (Peptidase family M12A) RRM_1 PF00076.22 EON98528.1 - 4.2e-64 212.3 2.0 2e-15 56.3 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EON98528.1 - 7.3e-07 29.1 0.0 0.27 11.3 0.0 4.9 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 EON98528.1 - 1.3e-05 25.0 0.1 8.1 6.2 0.0 4.8 5 0 0 5 5 5 3 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 EON98528.1 - 1.4e-05 24.8 0.0 0.27 11.1 0.0 3.7 4 0 0 4 4 4 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EON98528.1 - 1.6e-05 24.8 0.1 0.58 10.3 0.0 4.5 4 1 0 4 4 4 2 Limkain b1 RRM_3 PF08777.11 EON98528.1 - 0.00053 20.0 0.2 1.2 9.2 0.0 4.0 3 0 0 3 3 3 1 RNA binding motif PHM7_cyt PF14703.6 EON98528.1 - 0.0034 17.6 4.6 5.5 7.2 0.0 5.5 4 2 1 5 5 5 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 EON98528.1 - 0.0087 16.2 0.0 44 4.3 0.0 4.4 5 0 0 5 5 5 0 RNA recognition motif DUF4817 PF16087.5 EON98528.1 - 0.11 12.3 0.3 6 6.8 0.0 3.4 4 0 0 4 4 4 0 Helix-turn-helix domain (DUF4817) Smg4_UPF3 PF03467.15 EON98528.1 - 0.15 12.0 0.0 0.15 12.0 0.0 3.9 5 0 0 5 5 5 0 Smg-4/UPF3 family tRNA-synt_2 PF00152.20 EON98529.1 - 1e-58 198.9 0.0 5.1e-48 163.8 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EON98529.1 - 2.8e-11 43.2 0.0 5.3e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EON98529.1 - 0.002 17.6 0.0 0.22 11.0 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Peptidase_S8 PF00082.22 EON98530.1 - 1.4e-35 123.0 0.0 2.2e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Mic1 PF07035.12 EON98530.1 - 0.086 12.5 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like TagA PF12561.8 EON98531.1 - 0.12 12.8 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 ToxR activated gene A lipoprotein domain AAA_18 PF13238.6 EON98532.1 - 7.1e-10 39.5 0.0 9.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 EON98532.1 - 0.0013 18.9 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase KTI12 PF08433.10 EON98532.1 - 0.0025 17.3 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EON98532.1 - 0.019 15.1 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EON98532.1 - 0.031 14.5 0.0 0.047 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain Torsin PF06309.11 EON98532.1 - 0.055 13.6 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Torsin APS_kinase PF01583.20 EON98532.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 EON98532.1 - 0.1 11.9 0.0 0.26 10.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Thymidylate_kin PF02223.17 EON98532.1 - 0.17 11.6 0.2 8.7 6.0 0.1 2.4 2 1 0 2 2 2 0 Thymidylate kinase dNK PF01712.19 EON98532.1 - 0.21 11.4 0.2 7 6.4 0.2 2.1 1 1 0 1 1 1 0 Deoxynucleoside kinase adh_short PF00106.25 EON98533.1 - 6.2e-34 117.2 2.1 8.2e-34 116.8 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON98533.1 - 4.8e-25 88.5 3.3 7.2e-25 87.9 3.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON98533.1 - 1.4e-05 25.1 4.5 3.7e-05 23.7 4.5 1.6 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EON98533.1 - 1.5e-05 24.1 0.0 2.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EON98533.1 - 0.00013 21.9 5.8 0.0003 20.8 5.8 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EON98533.1 - 0.0022 17.5 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EON98534.1 - 1.5e-63 214.5 0.0 1.9e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EON98534.1 - 2.1e-17 63.6 0.0 2.7e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EON98534.1 - 0.00054 19.1 0.1 0.00079 18.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sugar_tr PF00083.24 EON98535.1 - 1.5e-15 57.0 5.3 2.2e-09 36.7 0.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter zf-Tim10_DDP PF02953.15 EON98536.1 - 1.4e-18 66.3 0.3 1.7e-18 66.0 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger GATA PF00320.27 EON98537.1 - 4.5e-16 58.2 5.4 1e-15 57.0 5.4 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 EON98537.1 - 5.8e-13 48.9 0.0 1.2e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EON98537.1 - 6.3e-09 35.8 0.1 1.7e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 EON98537.1 - 7e-05 22.9 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 EON98537.1 - 0.00053 20.2 0.1 0.0022 18.2 0.0 2.0 2 0 0 2 2 2 1 PAS domain eIF3_subunit PF08597.10 EON98537.1 - 0.0079 16.1 0.2 0.016 15.1 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Zn-ribbon_8 PF09723.10 EON98537.1 - 0.0099 16.0 0.2 0.02 15.0 0.2 1.5 1 0 0 1 1 1 1 Zinc ribbon domain PAS_4 PF08448.10 EON98537.1 - 0.011 16.0 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 PAS fold DUF3474 PF11960.8 EON98537.1 - 0.034 14.3 0.2 0.23 11.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) TF_Zn_Ribbon PF08271.12 EON98537.1 - 0.17 11.4 0.7 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding APG6_N PF17675.1 EON98537.1 - 0.24 11.9 3.3 0.5 10.9 3.3 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4428 PF14471.6 EON98537.1 - 4.3 7.3 6.2 0.89 9.5 0.9 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Pkinase PF00069.25 EON98538.1 - 2.3e-64 217.3 0.0 4.6e-64 216.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON98538.1 - 8.8e-37 126.8 0.0 7.8e-31 107.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EON98538.1 - 4.1e-07 29.6 0.1 0.0011 18.4 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 EON98538.1 - 5.1e-05 23.3 0.1 0.00045 20.2 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EON98538.1 - 0.002 17.5 0.2 0.0037 16.7 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EON98538.1 - 0.0082 15.1 0.1 0.012 14.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EON98538.1 - 0.02 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family zf-C2H2_aberr PF17017.5 EON98539.1 - 2.2e-05 24.7 2.5 0.016 15.4 0.2 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 EON98539.1 - 7.2e-05 23.3 12.3 0.019 15.8 1.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EON98539.1 - 0.0011 19.4 12.8 0.088 13.3 1.6 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EON98539.1 - 0.013 15.9 0.9 0.013 15.9 0.9 3.5 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EON98539.1 - 0.018 15.3 2.0 1.6 9.1 0.3 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 EON98539.1 - 0.16 12.4 1.0 0.31 11.5 0.2 1.8 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 EON98539.1 - 3.7 7.6 10.8 0.18 11.9 2.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger WD40 PF00400.32 EON98540.1 - 0.0026 18.5 0.1 7 7.7 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Na_Ca_ex PF01699.24 EON98541.1 - 3.7e-41 140.6 39.1 8.3e-21 74.5 20.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3087 PF11286.8 EON98541.1 - 0.064 12.7 0.3 0.17 11.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Saw1 PF11561.8 EON98542.1 - 0.0074 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Single strand annealing-weakened 1 Ezh2_MCSS PF18600.1 EON98543.1 - 1.7e-27 94.8 0.4 3.3e-27 93.9 0.4 1.5 1 0 0 1 1 1 1 MCSS domain SET PF00856.28 EON98543.1 - 1.2e-16 61.5 0.4 1.8e-14 54.5 0.1 3.4 2 1 0 2 2 2 1 SET domain EZH2_N PF18601.1 EON98543.1 - 5.4e-10 39.5 0.9 1.5e-09 38.0 0.5 2.0 2 0 0 2 2 2 1 EZH2 N-terminal domain DUF592 PF04574.13 EON98543.1 - 0.025 14.3 0.0 0.079 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF592) Kelch_4 PF13418.6 EON98544.1 - 6.7e-28 96.5 8.4 1.3e-08 34.7 0.0 5.0 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EON98544.1 - 2.3e-23 81.6 3.1 4.8e-05 23.5 0.0 5.8 5 1 1 6 6 6 4 Kelch motif Kelch_5 PF13854.6 EON98544.1 - 3.3e-22 78.0 9.8 1.3e-06 28.3 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EON98544.1 - 5.5e-21 73.9 1.7 6.1e-05 22.5 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 EON98544.1 - 6.2e-21 74.2 4.0 9.4e-07 29.0 0.1 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EON98544.1 - 6e-17 60.9 5.7 0.0017 18.2 0.0 5.3 5 0 0 5 5 5 4 Kelch motif BTB PF00651.31 EON98544.1 - 6.1e-09 36.1 0.0 1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PPP4R2 PF09184.11 EON98545.1 - 2.1e-07 30.8 0.9 7.5e-06 25.7 0.0 2.8 3 0 0 3 3 3 1 PPP4R2 FAD-oxidase_C PF02913.19 EON98546.1 - 7.7e-61 205.9 1.7 9.6e-61 205.6 0.1 1.9 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EON98546.1 - 1.6e-35 121.9 0.0 2.9e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Transp_cyt_pur PF02133.15 EON98547.1 - 2.5e-46 158.3 27.2 3.3e-46 158.0 27.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3752 PF12572.8 EON98548.1 - 4.3e-49 166.9 7.6 5.1e-49 166.7 7.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Kelch_1 PF01344.25 EON98549.1 - 1.3e-41 139.9 17.3 1.1e-08 34.6 0.3 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 EON98549.1 - 3.8e-39 132.1 17.5 1.2e-06 28.3 0.1 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 EON98549.1 - 5.3e-39 131.8 18.5 2.8e-08 33.8 0.0 7.0 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.6 EON98549.1 - 3.5e-36 123.0 17.8 1.2e-06 28.4 0.1 6.9 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EON98549.1 - 5.2e-34 115.4 17.3 1.8e-06 28.0 0.1 6.9 5 2 2 7 7 7 6 Kelch motif Kelch_2 PF07646.15 EON98549.1 - 1.9e-31 106.8 14.9 1.6e-07 31.0 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Ecl1 PF12855.7 EON98549.1 - 3.4 8.8 20.6 7.7 7.6 20.6 1.6 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Dus PF01207.17 EON98551.1 - 4.5e-38 131.1 0.0 1.3e-29 103.3 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) DEAD PF00270.29 EON98552.1 - 1.6e-27 96.4 0.3 5.4e-26 91.4 0.0 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON98552.1 - 1.2e-23 83.6 0.0 3.4e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON98552.1 - 0.0034 17.4 0.1 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SMYLE_N PF18615.1 EON98552.1 - 2 7.9 6.2 3.8 7.0 6.2 1.4 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Fil_haemagg PF05594.14 EON98553.1 - 0.14 12.7 1.8 0.26 11.8 1.8 1.4 1 0 0 1 1 1 0 Haemagluttinin repeat ATP-synt_G PF04718.15 EON98555.1 - 4.3e-33 114.1 0.8 7.8e-33 113.3 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit SPRY PF00622.28 EON98556.1 - 2.1e-06 27.8 0.0 3.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Glyco_tranf_2_3 PF13641.6 EON98557.1 - 2.8e-23 83.0 0.0 3.4e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EON98557.1 - 5.2e-09 36.1 0.0 2.4e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EON98557.1 - 0.00051 19.6 0.0 0.0014 18.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 PH_6 PF15406.6 EON98558.1 - 2.1e-41 140.7 1.6 2.1e-41 140.7 1.6 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EON98558.1 - 1.3e-05 25.7 0.0 5.2e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 PH domain HATPase_c PF02518.26 EON98559.1 - 5.2e-24 84.9 0.1 9.6e-24 84.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EON98559.1 - 6e-19 68.3 0.0 1.3e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EON98559.1 - 1.9e-07 31.0 0.0 5.7e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 EON98559.1 - 4.3e-05 23.5 0.0 0.00011 22.1 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EON98559.1 - 5.9e-05 23.3 0.0 0.00023 21.3 0.0 2.1 1 1 0 1 1 1 1 PAS domain PAS_8 PF13188.7 EON98559.1 - 0.00058 19.8 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EON98559.1 - 0.0021 18.3 0.6 0.0055 17.0 0.1 2.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EON98559.1 - 0.0031 17.7 0.0 0.0079 16.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold Amidase PF01425.21 EON98560.1 - 1.6e-53 182.3 0.0 2.8e-53 181.5 0.0 1.3 1 1 0 1 1 1 1 Amidase Isochorismatase PF00857.20 EON98561.1 - 3.8e-17 63.0 0.0 4.3e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family 4F5 PF04419.14 EON98562.1 - 2.3e-07 31.6 10.4 4.1e-07 30.7 10.4 1.4 1 0 0 1 1 1 1 4F5 protein family zf-met2 PF12907.7 EON98562.1 - 0.00045 20.3 0.8 0.00091 19.3 0.8 1.5 1 0 0 1 1 1 1 Zinc-binding DUF4921 PF16268.5 EON98562.1 - 0.09 11.6 0.1 0.093 11.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4921) HHH PF00633.23 EON98563.1 - 0.0026 17.5 0.1 0.0071 16.2 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif zf-RING_2 PF13639.6 EON98564.1 - 1e-11 44.9 6.7 1.6e-11 44.3 6.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EON98564.1 - 5.8e-08 32.4 6.4 9.2e-08 31.8 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EON98564.1 - 7.2e-08 32.2 3.8 1.2e-07 31.5 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EON98564.1 - 7.2e-08 32.0 0.9 1.3e-07 31.2 0.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EON98564.1 - 9.8e-07 29.0 8.0 3.4e-06 27.2 8.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EON98564.1 - 9.2e-06 25.5 3.7 1.5e-05 24.8 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EON98564.1 - 0.0017 18.4 2.6 0.0039 17.2 2.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EON98564.1 - 0.0025 17.6 2.6 0.0038 17.0 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EON98564.1 - 0.0029 17.6 0.9 0.0029 17.6 0.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 EON98564.1 - 0.023 14.5 6.5 0.042 13.7 6.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EON98564.1 - 0.2 11.5 4.7 0.41 10.6 4.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 EON98564.1 - 0.23 11.4 6.0 0.42 10.5 6.0 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 EON98564.1 - 0.44 10.8 3.2 1.2 9.4 3.2 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EON98564.1 - 0.79 9.4 5.2 1.4 8.6 5.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EON98564.1 - 0.88 9.8 4.6 2 8.7 4.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING OAD_gamma PF04277.13 EON98564.1 - 1.1 9.9 0.0 1.1 9.9 0.0 2.8 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain RINGv PF12906.7 EON98564.1 - 1.6 8.9 5.0 4 7.6 3.7 2.3 2 1 0 2 2 2 0 RING-variant domain zf-C3H2C3 PF17122.5 EON98564.1 - 3.4 7.8 5.7 7.4 6.7 5.7 1.6 1 0 0 1 1 1 0 Zinc-finger TFIIA PF03153.13 EON98565.1 - 3.2e-86 290.9 12.7 8.5e-86 289.5 12.7 1.6 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 EON98565.1 - 0.00033 20.5 6.5 0.00047 20.0 6.5 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3295 PF11702.8 EON98565.1 - 0.065 12.6 5.3 0.099 12.0 5.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3295) DNA_pol_phi PF04931.13 EON98565.1 - 0.17 10.0 8.9 0.22 9.6 8.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi YL1 PF05764.13 EON98565.1 - 0.18 11.9 4.3 0.32 11.1 4.3 1.4 1 0 0 1 1 1 0 YL1 nuclear protein XPG_N PF00752.17 EON98566.1 - 3.5e-32 110.9 0.0 8e-32 109.7 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EON98566.1 - 2.5e-27 95.1 0.0 9.1e-27 93.3 0.0 2.1 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 EON98566.1 - 0.00028 20.6 0.6 0.00028 20.6 0.6 3.0 2 0 0 2 2 2 1 Ubiquitin interaction motif 5_3_exonuc PF01367.20 EON98566.1 - 0.037 14.6 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Troponin PF00992.20 EON98567.1 - 0.064 13.6 7.0 1.8 8.9 4.2 2.2 2 0 0 2 2 2 0 Troponin TEA PF01285.18 EON98568.1 - 1.9e-23 82.3 0.0 4.5e-23 81.1 0.0 1.7 1 0 0 1 1 1 1 TEA/ATTS domain Pex14_N PF04695.13 EON98568.1 - 3.1 8.4 12.6 10 6.8 12.6 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 EON98568.1 - 3.8 7.0 14.4 6.9 6.2 14.4 1.3 1 0 0 1 1 1 0 Spt20 family Bap31 PF05529.12 EON98570.1 - 3.2e-49 166.3 9.4 4.2e-49 165.9 9.4 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EON98570.1 - 9.8e-13 47.9 5.5 9.8e-13 47.9 5.5 2.3 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain V_ATPase_I PF01496.19 EON98570.1 - 0.015 13.3 0.7 0.024 12.6 0.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CEP63 PF17045.5 EON98570.1 - 0.022 14.7 1.9 0.037 13.9 1.9 1.4 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa TPD52 PF04201.15 EON98570.1 - 0.087 12.4 1.1 0.13 11.9 1.1 1.3 1 0 0 1 1 1 0 Tumour protein D52 family DivIC PF04977.15 EON98570.1 - 0.13 12.1 8.2 0.32 10.8 1.4 3.5 4 0 0 4 4 4 0 Septum formation initiator Spc7 PF08317.11 EON98570.1 - 0.15 10.9 3.8 0.22 10.4 3.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 EON98570.1 - 0.48 9.7 4.6 0.088 12.2 1.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) XhlA PF10779.9 EON98570.1 - 0.55 10.5 4.7 2.2 8.6 0.6 2.4 2 0 0 2 2 2 0 Haemolysin XhlA Csm1_N PF18504.1 EON98570.1 - 0.62 10.4 6.1 0.13 12.6 1.3 2.1 2 0 0 2 2 2 0 Csm1 N-terminal domain TMEM192 PF14802.6 EON98570.1 - 2.4 7.2 6.5 0.26 10.4 0.2 2.0 2 1 0 2 2 2 0 TMEM192 family DUF1971 PF09313.11 EON98571.1 - 0.06 13.4 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) PsbI PF02532.14 EON98571.1 - 0.063 13.2 0.2 0.063 13.2 0.2 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) 2OG-FeII_Oxy PF03171.20 EON98573.1 - 8e-14 52.0 0.0 1.3e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily OHCU_decarbox PF09349.10 EON98573.1 - 0.0048 17.4 0.1 0.012 16.1 0.1 1.6 2 0 0 2 2 2 1 OHCU decarboxylase PG_binding_1 PF01471.18 EON98574.1 - 3.5e-05 23.9 3.3 0.0048 17.1 0.1 3.2 3 0 0 3 3 3 1 Putative peptidoglycan binding domain FPP PF05911.11 EON98574.1 - 0.0016 16.8 2.4 0.0025 16.1 2.4 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Tropomyosin_1 PF12718.7 EON98574.1 - 0.003 17.7 4.3 0.003 17.7 4.3 2.4 2 1 1 3 3 3 1 Tropomyosin like XhlA PF10779.9 EON98574.1 - 0.0064 16.7 0.2 0.018 15.2 0.2 1.8 1 0 0 1 1 1 1 Haemolysin XhlA DUF1664 PF07889.12 EON98574.1 - 0.0076 16.3 3.6 0.019 15.0 3.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Spc7 PF08317.11 EON98574.1 - 0.0089 14.9 3.6 0.017 14.0 3.6 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein SlyX PF04102.12 EON98574.1 - 0.02 15.5 8.2 0.54 10.9 1.8 2.8 1 1 1 2 2 2 0 SlyX Laminin_II PF06009.12 EON98574.1 - 0.021 14.8 2.7 0.072 13.1 2.6 1.8 1 1 0 1 1 1 0 Laminin Domain II ATG16 PF08614.11 EON98574.1 - 0.19 11.9 6.1 0.53 10.5 6.1 1.7 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) MIP-T3_C PF17749.1 EON98574.1 - 0.2 11.6 2.1 0.55 10.2 2.1 1.7 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region DUF2203 PF09969.9 EON98574.1 - 0.26 12.0 2.5 0.86 10.3 2.5 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Kre28 PF17097.5 EON98574.1 - 0.26 10.2 4.5 0.37 9.7 4.5 1.1 1 0 0 1 1 1 0 Spindle pole body component Syntaxin-6_N PF09177.11 EON98574.1 - 0.3 11.6 3.4 1 10.0 3.4 1.9 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF948 PF06103.11 EON98574.1 - 0.33 11.2 3.3 0.29 11.4 1.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 EON98574.1 - 0.47 10.6 2.8 1 9.5 2.8 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.6 EON98574.1 - 0.49 9.0 3.9 0.84 8.2 3.9 1.3 1 0 0 1 1 1 0 AAA domain THOC7 PF05615.13 EON98574.1 - 0.57 10.5 5.4 2.3 8.5 5.5 1.9 1 1 0 1 1 1 0 Tho complex subunit 7 CCDC-167 PF15188.6 EON98574.1 - 0.59 10.5 6.1 2.8 8.4 0.0 2.9 3 0 0 3 3 2 0 Coiled-coil domain-containing protein 167 BLOC1_2 PF10046.9 EON98574.1 - 0.63 10.4 4.7 1.2 9.5 3.2 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ERM PF00769.19 EON98574.1 - 1 9.1 5.3 2.8 7.7 5.3 1.7 1 0 0 1 1 1 0 Ezrin/radixin/moesin family APG6_N PF17675.1 EON98574.1 - 2.2 8.8 9.7 0.85 10.2 6.0 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF16 PF01519.16 EON98574.1 - 3.6 8.1 5.1 4.2 7.9 3.1 2.1 2 1 0 2 2 1 0 Protein of unknown function DUF16 SUR7 PF06687.12 EON98575.1 - 4e-35 121.4 15.6 5.3e-35 121.0 15.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family LMF1 PF06762.14 EON98575.1 - 0.38 9.8 2.6 0.48 9.5 2.6 1.1 1 0 0 1 1 1 0 Lipase maturation factor DUF2700 PF10912.8 EON98575.1 - 0.59 10.2 11.1 1.2 9.1 11.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) DUF4064 PF13273.6 EON98575.1 - 0.72 10.2 11.5 0.3 11.4 2.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) COS PF18568.1 EON98575.1 - 1.9 8.5 4.0 12 5.9 0.5 2.3 2 0 0 2 2 2 0 TRIM C-terminal subgroup One Signature domain Aldedh PF00171.22 EON98576.1 - 5.4e-130 434.0 0.0 6.1e-130 433.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family baeRF_family2 PF18844.1 EON98576.1 - 0.67 10.0 3.8 0.23 11.5 0.7 1.8 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 Metallophos PF00149.28 EON98577.1 - 6.3e-35 121.5 0.1 9.7e-35 120.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EON98577.1 - 1.7e-16 60.4 0.0 3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain ANAPC4_WD40 PF12894.7 EON98578.1 - 9.3e-17 61.1 5.0 9.5e-05 22.6 0.1 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EON98578.1 - 2.3e-16 59.9 18.2 0.00033 21.4 0.1 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EON98578.1 - 4e-06 26.0 0.0 0.00033 19.7 0.0 3.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EON98578.1 - 5.9e-06 26.3 0.2 0.00027 20.9 0.1 2.4 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Pil1 PF13805.6 EON98580.1 - 3.2e-125 417.0 0.0 3.9e-125 416.7 0.0 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 HIG_1_N PF04588.13 EON98581.1 - 9e-07 29.0 3.3 9e-07 29.0 3.3 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region TauE PF01925.19 EON98581.1 - 0.013 15.1 0.3 0.013 15.1 0.3 2.2 2 1 0 2 2 2 0 Sulfite exporter TauE/SafE Romo1 PF10247.9 EON98581.1 - 0.02 15.2 1.8 0.045 14.1 1.8 1.6 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF981 PF06168.11 EON98581.1 - 0.075 13.0 0.6 0.12 12.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF981) CLTH PF10607.9 EON98582.1 - 5.8e-32 110.6 0.0 9.2e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EON98582.1 - 6.2e-08 32.5 0.2 1.1e-07 31.7 0.2 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 EON98582.1 - 0.00044 19.7 0.0 0.00075 18.9 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger Flagellin_C PF00700.21 EON98582.1 - 0.0012 19.1 0.1 0.0041 17.4 0.1 1.9 1 1 0 1 1 1 1 Bacterial flagellin C-terminal helical region zf-RING_5 PF14634.6 EON98582.1 - 0.0017 18.3 0.2 0.0028 17.6 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EON98582.1 - 0.0022 18.3 0.3 0.0036 17.6 0.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EON98582.1 - 0.0071 16.2 0.4 0.013 15.4 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EON98582.1 - 0.032 14.1 0.2 0.06 13.2 0.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EON98582.1 - 0.088 12.7 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EON98582.1 - 0.1 12.4 1.0 0.18 11.7 1.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EON98582.1 - 0.18 12.0 0.6 0.34 11.1 0.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Glyco_hydro_79C PF16862.5 EON98583.1 - 1e-22 81.0 0.6 2e-22 80.0 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain ECH_1 PF00378.20 EON98584.1 - 2.5e-42 144.9 0.0 3.8e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON98584.1 - 2.2e-20 73.4 0.0 4.8e-20 72.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SURF2 PF05477.11 EON98584.1 - 0.28 10.9 3.0 0.51 10.0 3.0 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) NAD_binding_8 PF13450.6 EON98585.1 - 1.3e-06 28.6 0.0 2.1e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EON98585.1 - 0.011 15.7 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding ADH_N PF08240.12 EON98587.1 - 3.3e-27 94.5 1.3 7.7e-27 93.3 1.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON98587.1 - 1.3e-14 54.2 0.1 2e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EON98587.1 - 7e-05 22.4 2.8 0.0028 17.2 2.8 2.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Aldedh PF00171.22 EON98588.1 - 8.9e-166 552.0 0.8 1e-165 551.8 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EON98588.1 - 0.0055 16.2 0.0 0.02 14.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Pro_isomerase PF00160.21 EON98589.1 - 2.6e-49 167.5 0.2 2.9e-49 167.4 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 EON98589.1 - 0.0051 16.8 0.0 0.0078 16.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain SLATT_4 PF18186.1 EON98591.1 - 0.24 11.1 0.0 0.41 10.3 0.0 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 tRNA-synt_1 PF00133.22 EON98592.1 - 3e-154 514.6 0.0 3.9e-154 514.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EON98592.1 - 2.5e-20 72.6 0.0 1.5e-13 50.3 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EON98592.1 - 1.7e-17 63.8 0.0 3.6e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 EON98592.1 - 0.00099 18.7 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EON98592.1 - 0.0031 16.9 0.0 0.87 8.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain AAA_23 PF13476.6 EON98593.1 - 1.6e-32 113.6 5.8 1.6e-32 113.6 5.8 7.7 2 2 5 7 7 7 1 AAA domain AAA_21 PF13304.6 EON98593.1 - 1.3e-11 44.9 5.0 0.00017 21.5 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON98593.1 - 1.3e-06 28.0 0.0 1.3e-06 28.0 0.0 3.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EON98593.1 - 6e-06 26.4 0.0 4e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EON98593.1 - 0.00085 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Jnk-SapK_ap_N PF09744.9 EON98593.1 - 0.0055 16.9 7.4 0.0055 16.9 7.4 9.6 2 1 6 9 9 9 1 JNK_SAPK-associated protein-1 AAA_16 PF13191.6 EON98593.1 - 0.079 13.3 0.0 0.079 13.3 0.0 5.5 4 3 1 5 5 5 0 AAA ATPase domain ABC_tran PF00005.27 EON98593.1 - 0.082 13.4 0.0 0.082 13.4 0.0 7.2 4 2 1 5 5 5 0 ABC transporter AAA_13 PF13166.6 EON98593.1 - 0.1 11.2 0.0 0.1 11.2 0.0 6.3 2 1 4 6 6 6 0 AAA domain UreF PF01730.16 EON98593.1 - 8.6 7.0 6.8 3.4 8.3 0.9 2.9 2 0 0 2 2 2 0 UreF adh_short PF00106.25 EON98594.1 - 1.3e-14 54.2 0.1 1.5e-14 53.9 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON98594.1 - 4.2e-08 33.0 0.1 4.6e-08 32.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON98594.1 - 0.0011 18.9 0.1 0.0012 18.8 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON98594.1 - 0.0025 17.3 0.0 0.0027 17.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PSY3 PF16836.5 EON98594.1 - 0.061 12.8 0.0 0.073 12.6 0.0 1.1 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description NAD_binding_10 PF13460.6 EON98594.1 - 0.11 12.4 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 NAD(P)H-binding RRF PF01765.19 EON98595.1 - 3.4e-31 108.4 3.3 4.5e-31 108.0 3.3 1.1 1 0 0 1 1 1 1 Ribosome recycling factor F-box-like PF12937.7 EON98595.1 - 0.13 12.1 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 F-box-like GIY-YIG PF01541.24 EON98595.1 - 0.3 11.4 1.0 10 6.5 0.4 2.4 2 0 0 2 2 2 0 GIY-YIG catalytic domain DUF733 PF05306.11 EON98595.1 - 0.53 10.6 5.7 1.2 9.5 5.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF733) Peroxin-13_N PF04088.13 EON98597.1 - 4.7e-52 176.1 0.4 8.8e-52 175.2 0.0 1.6 2 0 0 2 2 2 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 EON98597.1 - 7.2e-08 32.0 0.0 1.8e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EON98597.1 - 1.5e-06 27.7 0.0 4.3e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EON98597.1 - 2.6e-05 24.0 0.0 5.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Med10 PF09748.9 EON98597.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Dynein_light PF01221.18 EON98598.1 - 1e-39 134.7 1.0 1.1e-39 134.6 1.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RNA_pol_N PF01194.17 EON98600.1 - 5.7e-30 103.4 2.3 6.8e-30 103.2 2.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit MmgE_PrpD PF03972.14 EON98600.1 - 0.15 10.6 0.0 0.15 10.6 0.0 1.0 1 0 0 1 1 1 0 MmgE/PrpD family Ank_2 PF12796.7 EON98601.1 - 2.3e-25 89.0 1.6 1.3e-12 48.1 0.4 4.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EON98601.1 - 4.1e-18 65.5 5.1 4.2e-07 30.4 0.2 6.4 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EON98601.1 - 1.3e-15 57.2 8.9 5.1e-07 29.8 0.7 5.7 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EON98601.1 - 9.3e-12 44.8 11.9 0.0011 19.3 0.5 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EON98601.1 - 1.5e-11 43.5 7.9 0.32 11.7 0.1 7.1 6 0 0 6 6 6 4 Ankyrin repeat TolA_bind_tri PF16331.5 EON98602.1 - 0.062 13.4 0.1 0.062 13.4 0.1 4.9 5 2 1 6 6 6 0 TolA binding protein trimerisation HALZ PF02183.18 EON98602.1 - 0.26 11.5 7.5 0.34 11.2 0.9 4.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper Shugoshin_N PF07558.11 EON98602.1 - 0.33 10.8 3.8 9.3 6.2 0.0 4.0 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region NAD_binding_4 PF07993.12 EON98603.1 - 2e-21 76.3 0.0 2.9e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EON98603.1 - 2.8e-07 30.2 0.0 4.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EON98603.1 - 2.1e-05 24.8 0.1 9.1e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site VCBS PF13517.6 EON98604.1 - 3.3e-30 104.5 55.7 3.2e-12 46.9 1.7 8.8 5 2 4 9 9 9 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 EON98604.1 - 5.8e-12 46.4 0.3 1.7e-11 44.8 0.3 1.9 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.8 EON98604.1 - 3.4e-09 36.3 5.7 0.11 11.9 0.0 6.3 4 2 2 6 6 6 4 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL PF00657.22 EON98604.1 - 7.3e-07 29.4 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FG-GAP PF01839.23 EON98604.1 - 0.0017 18.4 44.3 0.0074 16.4 0.2 7.5 8 0 0 8 8 8 4 FG-GAP repeat HalOD2 PF18547.1 EON98604.1 - 0.08 12.9 2.7 0.9 9.5 0.1 3.2 2 0 0 2 2 2 0 Halobacterial output domain 2 CENP-B_N PF04218.13 EON98605.1 - 0.014 15.0 0.1 1.2 8.8 0.0 2.9 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain DUF4891 PF16232.5 EON98605.1 - 0.47 11.0 2.8 56 4.3 0.1 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4891) AA_permease PF00324.21 EON98606.1 - 2.6e-104 349.5 28.4 3.1e-104 349.2 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON98606.1 - 7.2e-19 67.9 27.1 9.3e-19 67.6 27.1 1.1 1 0 0 1 1 1 1 Amino acid permease MMR_HSR1 PF01926.23 EON98607.1 - 6.4e-22 77.8 0.0 1.3e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EON98607.1 - 5.7e-08 32.4 0.0 9.9e-08 31.7 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Adenylsucc_synt PF00709.21 EON98608.1 - 1.5e-83 281.1 0.0 1.8e-40 139.2 0.0 2.5 1 1 1 2 2 2 2 Adenylosuccinate synthetase MFS_1 PF07690.16 EON98609.1 - 1.4e-40 139.3 30.0 1.4e-40 139.3 30.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 EON98609.1 - 0.0035 17.1 3.5 0.011 15.5 3.5 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Phage_holin_2_1 PF04971.12 EON98609.1 - 0.66 10.0 4.9 0.35 10.9 1.5 2.3 2 0 0 2 2 2 0 Bacteriophage P21 holin S HAGH_C PF16123.5 EON98610.1 - 1.5e-23 83.1 0.3 2.6e-23 82.3 0.3 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EON98610.1 - 1.1e-17 64.7 3.0 1.8e-16 60.8 3.0 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EON98610.1 - 3.7e-05 23.3 0.6 0.00026 20.6 0.6 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HYR PF02494.16 EON98610.1 - 0.044 14.1 0.0 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 HYR domain HGTP_anticodon2 PF12745.7 EON98611.1 - 5.1e-84 281.9 2.8 5.1e-84 281.9 2.8 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 EON98611.1 - 1.1e-43 149.6 0.2 1.7e-21 76.7 0.0 4.9 3 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 EON98611.1 - 7.6e-22 77.8 0.0 9e-11 41.5 0.0 3.8 3 1 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 EON98611.1 - 4e-16 59.2 0.0 4e-16 59.2 0.0 2.2 3 0 0 3 3 3 1 Histidyl-tRNA synthetase RWD PF05773.22 EON98611.1 - 2.1e-12 47.3 1.6 2.4e-12 47.2 0.1 2.0 2 0 0 2 2 2 1 RWD domain APH PF01636.23 EON98611.1 - 0.21 11.5 3.4 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L31 PF01197.18 EON98612.1 - 0.00041 20.5 0.0 0.00095 19.3 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L31 Oest_recep PF02159.15 EON98612.1 - 0.26 11.8 2.2 0.62 10.5 0.2 2.1 1 1 1 2 2 2 0 Oestrogen receptor DUF3187 PF11383.8 EON98613.1 - 0.07 12.3 0.3 0.11 11.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3187) PTR2 PF00854.21 EON98614.1 - 3.1e-80 270.0 6.3 4.5e-80 269.4 6.3 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EON98614.1 - 4e-07 29.3 19.8 6.9e-07 28.5 17.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DHHC PF01529.20 EON98615.1 - 2e-37 128.3 6.3 2e-37 128.3 6.3 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.17 EON98615.1 - 0.032 13.9 0.8 0.032 13.9 0.8 2.1 2 0 0 2 2 2 0 Yip1 domain zf-CRD PF17979.1 EON98615.1 - 0.81 9.8 10.8 0.064 13.4 5.7 1.7 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions FtsX PF02687.21 EON98615.1 - 5.7 7.5 15.4 0.83 10.2 7.8 2.7 2 1 1 3 3 3 0 FtsX-like permease family JmjC PF02373.22 EON98617.1 - 0.16 12.4 0.0 0.34 11.4 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase MFS_1 PF07690.16 EON98618.1 - 1e-42 146.3 55.0 2.7e-41 141.7 56.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EON98618.1 - 1.7e-09 36.7 16.6 1.7e-09 36.7 16.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) polyprenyl_synt PF00348.17 EON98619.1 - 1.6e-91 305.9 0.0 2e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase RNase_H2-Ydr279 PF09468.10 EON98619.1 - 0.04 14.1 0.2 0.2 11.8 0.2 2.0 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain DNMT1-RFD PF12047.8 EON98621.1 - 0.00053 20.1 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain CENP-B_dimeris PF09026.10 EON98621.1 - 0.12 12.7 4.5 37 4.8 0.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 EON98621.1 - 0.71 9.6 4.3 1.1 8.9 4.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Atrophin-1 PF03154.15 EON98622.1 - 0.53 8.5 6.1 0.58 8.4 6.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family Fungal_trans PF04082.18 EON98623.1 - 1.7e-18 66.6 0.1 2.9e-18 65.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EON98623.1 - 7.2e-09 35.6 8.0 1.1e-08 35.0 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.24 EON98623.1 - 0.18 11.4 0.0 0.44 10.1 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase GCD14 PF08704.10 EON98624.1 - 1.5e-63 214.8 6.8 3.6e-47 161.1 0.0 3.9 3 1 0 3 3 3 2 tRNA methyltransferase complex GCD14 subunit FLILHELTA PF10306.9 EON98625.1 - 2.4e-30 104.8 0.1 3.8e-30 104.1 0.1 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EON98625.1 - 0.002 18.6 0.1 0.0035 17.8 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Peptidase_M18 PF02127.15 EON98626.1 - 2.9e-129 431.6 0.0 3.3e-129 431.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Chromo PF00385.24 EON98627.1 - 7.1e-15 54.7 4.0 1.8e-12 47.0 0.2 2.7 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 EON98627.1 - 0.0026 17.9 0.5 0.11 12.7 0.0 2.4 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 ABC_membrane PF00664.23 EON98628.1 - 1.5e-49 169.1 39.3 4.1e-32 111.9 17.6 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EON98628.1 - 9.4e-48 162.2 0.0 2.2e-26 93.0 0.0 2.8 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 EON98628.1 - 6.3e-06 26.3 1.8 0.049 13.7 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 EON98628.1 - 4.6e-05 23.0 1.0 1.4 8.3 0.0 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 EON98628.1 - 5.6e-05 22.5 0.0 0.0055 16.0 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 EON98628.1 - 6e-05 23.5 0.0 0.31 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EON98628.1 - 9.4e-05 22.4 0.8 0.068 13.1 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EON98628.1 - 0.00012 21.7 1.1 0.18 11.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EON98628.1 - 0.00037 21.0 0.2 0.92 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 EON98628.1 - 0.0012 19.0 3.3 0.12 12.4 0.4 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_21 PF13304.6 EON98628.1 - 0.0013 18.6 0.3 1.7 8.4 0.1 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 EON98628.1 - 0.0016 17.4 2.3 0.53 9.2 0.1 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EON98628.1 - 0.0022 17.8 1.9 0.98 9.1 0.1 2.6 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 EON98628.1 - 0.0079 16.5 0.8 7.5 6.8 0.0 3.2 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EON98628.1 - 0.013 14.4 0.6 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.23 EON98628.1 - 0.016 15.3 4.9 0.095 12.8 0.7 2.6 2 0 0 2 2 2 0 Dynamin family AAA_15 PF13175.6 EON98628.1 - 0.025 14.3 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Ploopntkinase3 PF18751.1 EON98628.1 - 0.03 14.2 0.1 10 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Roc PF08477.13 EON98628.1 - 0.034 14.4 0.2 5.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EON98628.1 - 0.087 12.3 0.3 2.3 7.7 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EON98628.1 - 0.09 12.1 0.0 12 5.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.6 EON98628.1 - 0.093 13.0 1.7 0.37 11.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EON98628.1 - 0.12 12.9 0.1 7.9 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EON98628.1 - 0.24 11.2 1.6 15 5.2 0.2 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 EON98628.1 - 0.3 11.0 1.2 2 8.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Fcf1 PF04900.12 EON98629.1 - 2e-28 98.6 1.2 2e-28 98.6 1.2 1.8 2 1 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 EON98629.1 - 1.3e-13 51.2 0.3 1.3e-13 51.2 0.3 1.6 2 0 0 2 2 2 1 PIN like domain Imm-NTF2 PF15655.6 EON98629.1 - 0.024 14.9 0.1 0.039 14.2 0.1 1.4 1 0 0 1 1 1 0 NTF2 fold immunity protein GCV_T PF01571.21 EON98629.1 - 0.075 12.4 0.1 0.21 10.9 0.1 1.6 1 1 1 2 2 2 0 Aminomethyltransferase folate-binding domain FemAB PF02388.16 EON98630.1 - 0.048 12.5 0.1 0.068 12.0 0.1 1.2 1 0 0 1 1 1 0 FemAB family Cyanate_lyase PF02560.14 EON98631.1 - 4.6e-29 100.1 0.0 6.7e-29 99.5 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 EON98631.1 - 7.5e-05 23.0 0.0 0.00012 22.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EON98631.1 - 0.00036 20.2 0.0 0.00075 19.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_3 PF01381.22 EON98631.1 - 0.00047 20.1 0.1 0.00073 19.5 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EON98631.1 - 0.053 13.5 0.1 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 EON98631.1 - 0.056 13.2 0.1 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain MKT1_C PF12246.8 EON98632.1 - 4.2e-75 252.1 0.1 6e-75 251.6 0.1 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 EON98632.1 - 9.2e-33 112.5 0.0 2e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 EON98632.1 - 0.00032 21.1 0.0 0.00087 19.7 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain TcdA_TcdB_pore PF12920.7 EON98632.1 - 0.17 10.1 0.0 0.28 9.4 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain SPC22 PF04573.12 EON98633.1 - 2.1e-40 138.0 1.8 2.6e-39 134.5 1.8 1.9 1 1 0 1 1 1 1 Signal peptidase subunit ABC_tran PF00005.27 EON98634.1 - 2.1e-51 174.1 0.0 2.2e-29 102.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EON98634.1 - 4.3e-48 164.3 24.9 8.5e-28 97.8 6.2 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region Adaptin_binding PF10199.9 EON98634.1 - 2.7e-10 40.9 4.7 2.7e-10 40.9 4.7 2.6 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 SMC_N PF02463.19 EON98634.1 - 2.7e-08 33.5 2.5 0.026 14.0 0.2 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EON98634.1 - 2.8e-08 34.5 3.3 8.9e-05 23.1 0.1 3.5 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EON98634.1 - 1.2e-05 25.8 0.3 0.077 13.4 0.1 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 EON98634.1 - 2.4e-05 24.3 0.2 0.42 10.4 0.0 3.4 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 EON98634.1 - 0.0001 21.5 0.0 0.02 13.9 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 EON98634.1 - 0.00019 21.7 0.0 3.7 7.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EON98634.1 - 0.00019 21.1 0.6 0.24 11.2 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EON98634.1 - 0.0004 20.3 0.0 0.94 9.4 0.0 3.4 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 EON98634.1 - 0.00045 20.3 0.0 0.14 12.3 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EON98634.1 - 0.0009 19.0 0.0 0.26 11.0 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF87 PF01935.17 EON98634.1 - 0.0012 19.0 0.8 0.044 13.9 0.1 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 EON98634.1 - 0.0087 15.8 2.1 1.8 8.2 0.2 3.6 4 0 0 4 4 3 1 AAA domain DEAD PF00270.29 EON98634.1 - 0.021 14.6 0.0 21 4.8 0.0 3.5 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_25 PF13481.6 EON98634.1 - 0.025 14.2 0.0 2 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EON98634.1 - 0.03 14.7 0.1 11 6.5 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EON98634.1 - 0.047 13.0 0.1 7.2 5.8 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 EON98634.1 - 0.049 13.1 0.1 9.1 5.8 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 EON98634.1 - 0.069 12.4 0.1 12 5.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EON98634.1 - 0.09 12.8 0.0 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CbiA PF01656.23 EON98634.1 - 0.12 12.4 0.0 1.2 9.2 0.0 2.7 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 EON98634.1 - 0.12 11.9 1.4 0.73 9.4 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EON98634.1 - 0.16 12.4 0.1 37 4.8 0.0 3.1 3 0 0 3 3 3 0 RNA helicase TrwB_AAD_bind PF10412.9 EON98634.1 - 0.17 10.8 3.0 7.3 5.4 0.3 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 EON98634.1 - 0.46 10.2 1.9 13 5.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF3632 PF12311.8 EON98635.1 - 1.9e-18 67.5 0.1 3.5e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Vps54 PF07928.12 EON98636.1 - 1.7e-52 177.4 0.0 3.7e-52 176.3 0.0 1.6 1 0 0 1 1 1 1 Vps54-like protein DUF2451 PF10474.9 EON98636.1 - 0.00012 22.0 0.0 0.00029 20.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) HicA_toxin PF07927.12 EON98636.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, Sigma70_ner PF04546.13 EON98636.1 - 0.95 9.3 9.1 2.7 7.8 9.1 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region TruB_N PF01509.18 EON98637.1 - 6.5e-44 149.9 0.0 1.6e-43 148.7 0.0 1.6 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EON98637.1 - 2.6e-05 24.3 0.0 5.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain UQ_con PF00179.26 EON98638.1 - 2.4e-36 124.5 0.0 3e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PH PF00169.29 EON98639.1 - 0.0001 22.7 1.1 0.00052 20.5 0.2 2.1 1 1 1 2 2 2 1 PH domain zf-MYND PF01753.18 EON98640.1 - 9.8e-08 32.0 20.6 2.7e-07 30.6 20.6 1.8 1 0 0 1 1 1 1 MYND finger zf-TAZ PF02135.16 EON98640.1 - 8.1 7.0 13.4 0.66 10.5 8.5 1.7 2 0 0 2 2 2 0 TAZ zinc finger Pmp3 PF01679.17 EON98641.1 - 1.5e-19 69.9 8.2 1.9e-19 69.6 8.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TctA PF01970.16 EON98641.1 - 0.53 8.9 3.4 0.6 8.8 3.4 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Hydantoinase_B PF02538.14 EON98642.1 - 6.5e-209 694.6 0.1 9e-209 694.1 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EON98642.1 - 2.4e-94 315.9 0.0 6.1e-94 314.5 0.0 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EON98642.1 - 4.5e-57 192.6 0.0 1.2e-55 188.0 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Glyco_hydro_7 PF00840.20 EON98643.1 - 3.2e-123 411.7 9.0 3.5e-123 411.5 9.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Iso_dh PF00180.20 EON98644.1 - 4.1e-59 200.5 0.0 4.6e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.11 EON98644.1 - 0.027 15.2 0.3 1.6 9.5 0.0 2.4 2 0 0 2 2 2 0 Phenylalanine zipper RmlD_sub_bind PF04321.17 EON98645.1 - 5e-51 173.5 0.0 6.4e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EON98645.1 - 2e-22 79.8 0.0 2.9e-22 79.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EON98645.1 - 1.1e-10 41.1 0.0 1.8e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EON98645.1 - 2.6e-10 40.2 0.0 5.9e-10 39.1 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EON98645.1 - 6.2e-10 38.5 0.0 4.9e-09 35.6 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EON98645.1 - 1.4e-08 34.2 0.1 1.5e-05 24.3 0.1 3.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EON98645.1 - 0.054 13.0 0.0 0.79 9.2 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family DapB_N PF01113.20 EON98645.1 - 0.062 13.4 0.1 0.16 12.1 0.1 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Peptidase_M20 PF01546.28 EON98646.1 - 1.9e-23 83.3 0.0 1.4e-22 80.4 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EON98646.1 - 3.8e-18 65.4 0.0 7.2e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EON98646.1 - 3.5e-08 33.4 0.0 5.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 MapZ_C2 PF18708.1 EON98646.1 - 0.13 12.6 0.0 0.69 10.2 0.0 2.0 2 0 0 2 2 2 0 MapZ extracellular C-terminal domain 2 Sec2p PF06428.11 EON98647.1 - 7.5e-11 41.9 7.8 7.5e-11 41.9 7.8 2.3 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF4795 PF16043.5 EON98647.1 - 0.044 13.4 4.5 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Laminin_II PF06009.12 EON98647.1 - 0.045 13.8 9.1 0.25 11.3 3.1 2.2 2 0 0 2 2 2 0 Laminin Domain II Spc7 PF08317.11 EON98647.1 - 0.077 11.9 9.8 0.24 10.2 0.1 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.12 EON98647.1 - 0.079 13.6 18.2 2 9.1 5.9 3.7 2 2 1 3 3 3 0 SlyX Jnk-SapK_ap_N PF09744.9 EON98647.1 - 0.094 12.9 12.8 1.2 9.4 7.3 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 EON98647.1 - 0.15 11.6 3.6 0.36 10.4 1.4 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit ECSIT PF06239.11 EON98647.1 - 0.24 10.5 1.6 0.28 10.2 0.6 1.5 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway DUF948 PF06103.11 EON98647.1 - 0.38 11.0 3.1 7.8 6.8 0.1 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Snapin_Pallidin PF14712.6 EON98647.1 - 0.54 10.7 6.2 5 7.6 0.0 2.4 2 1 0 2 2 2 0 Snapin/Pallidin DUF4407 PF14362.6 EON98647.1 - 1.5 8.1 8.4 6.1 6.1 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 EON98647.1 - 2.2 7.3 8.1 5.5 6.0 0.1 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS6_N PF14661.6 EON98647.1 - 3 7.4 7.4 7.5 6.1 4.9 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus YlqD PF11068.8 EON98647.1 - 4.1 7.8 10.0 1.7 9.1 4.5 2.1 2 0 0 2 2 2 0 YlqD protein APG6_N PF17675.1 EON98647.1 - 4.8 7.7 14.3 4.9 7.7 0.6 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Syntaxin-6_N PF09177.11 EON98647.1 - 6.6 7.4 9.3 4.1 8.0 0.2 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Prefoldin PF02996.17 EON98647.1 - 9.4 6.2 9.2 19 5.2 0.5 2.5 2 1 0 2 2 2 0 Prefoldin subunit EF-hand_7 PF13499.6 EON98648.1 - 0.01 16.3 0.0 2.6 8.6 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 EON98648.1 - 0.024 14.2 0.3 5.3 6.8 0.0 4.3 6 0 0 6 6 6 0 EF hand EF-hand_9 PF14658.6 EON98648.1 - 0.12 12.7 0.3 6.9 7.1 0.0 2.7 1 1 2 3 3 3 0 EF-hand domain TRI12 PF06609.13 EON98649.1 - 1.3e-57 195.5 23.3 1.6e-57 195.3 23.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EON98649.1 - 5.1e-24 84.9 53.1 5.7e-24 84.7 47.7 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TPR_8 PF13181.6 EON98650.1 - 6.6e-17 60.3 7.6 0.0022 18.1 0.0 6.0 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EON98650.1 - 1.3e-13 50.1 2.0 0.0045 16.7 0.4 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EON98650.1 - 2.7e-09 37.1 10.7 0.025 15.4 0.0 5.1 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EON98650.1 - 5e-09 35.6 12.1 1.5 9.1 0.0 6.1 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EON98650.1 - 1.1e-08 35.5 7.9 2.9e-06 27.8 0.3 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EON98650.1 - 5.3e-08 33.3 3.9 2.2 8.8 0.0 4.6 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EON98650.1 - 1.9e-07 30.6 1.2 6.2e-07 29.0 0.1 2.5 3 0 0 3 3 3 1 TPR repeat ANAPC3 PF12895.7 EON98650.1 - 0.00012 22.2 0.2 0.2 11.9 0.0 2.7 3 0 0 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EON98650.1 - 0.00021 21.5 9.2 0.9 9.9 0.0 5.1 3 3 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EON98650.1 - 0.00028 21.0 0.1 3.1 8.4 0.0 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EON98650.1 - 0.0011 19.0 1.6 3 8.0 0.0 4.2 3 2 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 EON98650.1 - 0.0017 18.5 0.9 0.0074 16.4 0.1 2.3 2 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_7 PF13176.6 EON98650.1 - 0.0033 17.3 8.3 13 6.0 0.0 5.3 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EON98650.1 - 0.0087 16.6 11.1 4.9 8.0 0.0 5.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EON98650.1 - 0.24 11.3 6.6 2.6 8.1 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF4398 PF14346.6 EON98650.1 - 0.35 11.5 4.0 0.23 12.1 1.6 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4398) F-box-like PF12937.7 EON98652.1 - 3.2e-07 30.1 0.4 9.1e-07 28.7 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EON98652.1 - 0.11 12.4 4.7 0.21 11.5 1.6 2.7 2 1 0 2 2 2 0 F-box domain LRR_4 PF12799.7 EON98652.1 - 0.8 10.2 2.6 1.3e+02 3.2 0.0 4.6 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) PAF-AH_p_II PF03403.13 EON98653.1 - 1.8e-05 23.4 0.0 0.0067 15.0 0.0 2.3 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II AltA1 PF16541.5 EON98654.1 - 1.2e-15 58.4 0.0 1.6e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Alternaria alternata allergen 1 Chorismate_bind PF00425.18 EON98654.1 - 0.17 11.4 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 chorismate binding enzyme Glycogen_syn PF05693.13 EON98655.1 - 0 1175.0 0.0 0 1174.8 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 EON98655.1 - 1.9e-05 24.7 0.1 4.1e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 EON98655.1 - 6.7e-05 22.7 0.1 0.00013 21.7 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EON98655.1 - 0.00011 21.7 0.0 0.02 14.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EON98655.1 - 0.0003 21.2 0.0 0.39 11.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EON98655.1 - 0.0004 20.9 0.1 0.0015 19.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain PI-PLC-X PF00388.19 EON98656.1 - 6.4e-60 200.9 0.0 1.2e-59 200.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EON98656.1 - 1.7e-42 144.3 0.0 4.3e-42 143.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EON98656.1 - 2.2e-07 31.1 0.0 6.3e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 EON98656.1 - 0.00018 21.9 2.5 0.0017 18.7 0.5 2.4 2 1 1 3 3 3 2 EF-hand domain pair PH_12 PF16457.5 EON98656.1 - 0.0011 19.5 0.1 0.015 15.8 0.1 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain EF-hand_like PF09279.11 EON98656.1 - 0.0096 16.4 0.0 0.031 14.8 0.0 1.9 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_6 PF13405.6 EON98656.1 - 0.022 14.7 0.9 0.2 11.7 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 EON98656.1 - 0.041 13.4 0.2 0.19 11.3 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_10 PF14788.6 EON98656.1 - 0.07 13.0 0.0 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 EF hand RRM_1 PF00076.22 EON98658.1 - 3e-16 59.0 0.1 3.8e-11 42.6 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EON98658.1 - 0.0013 18.8 0.0 0.49 10.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 EON98658.1 - 0.012 15.5 0.0 4 7.4 0.0 2.4 2 1 0 2 2 2 0 Occluded RNA-recognition motif Pkinase PF00069.25 EON98659.1 - 1.5e-70 237.6 0.0 2e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON98659.1 - 2.8e-36 125.1 0.0 6.5e-36 123.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EON98659.1 - 0.00011 21.6 0.1 0.00038 19.9 0.1 1.8 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EON98659.1 - 0.0018 17.3 0.0 0.024 13.6 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EON98659.1 - 0.004 16.6 0.6 0.0081 15.5 0.6 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EON98659.1 - 0.018 14.7 0.1 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 RIO1 family PIP49_C PF12260.8 EON98659.1 - 0.037 13.7 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 APH PF01636.23 EON98659.1 - 0.058 13.3 1.0 0.27 11.1 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EON98659.1 - 0.07 11.9 0.0 0.07 11.9 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase TP53IP5 PF15331.6 EON98659.1 - 1 9.5 4.7 1.7 8.8 4.7 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 XRN_M PF17846.1 EON98660.1 - 4.1e-99 332.5 3.9 7e-99 331.8 3.9 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 EON98660.1 - 1.9e-96 322.2 0.0 3e-96 321.5 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 EON98660.1 - 6.6e-76 254.4 0.0 1.2e-75 253.5 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 EON98660.1 - 2.6e-34 117.3 0.0 8.2e-34 115.7 0.0 2.0 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 EON98660.1 - 7.1e-24 83.7 0.2 1.5e-23 82.7 0.2 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 EON98660.1 - 2.2e-05 24.5 0.0 8.1e-05 22.6 0.0 2.0 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 Acetyltransf_6 PF13480.7 EON98660.1 - 0.075 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DsrD PF08679.11 EON98660.1 - 0.11 12.8 0.2 0.29 11.4 0.2 1.7 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) DUF1345 PF07077.11 EON98660.1 - 0.12 12.0 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) DUF2711 PF10924.8 EON98660.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) DUF1244 PF06844.11 EON98660.1 - 0.19 11.9 0.8 0.65 10.2 0.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) Proteasome PF00227.26 EON98661.1 - 1.6e-35 122.3 0.0 2e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sigma54_AID PF00309.20 EON98661.1 - 0.25 11.2 0.0 0.53 10.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) SPX PF03105.19 EON98662.1 - 5.6e-55 187.8 8.8 5.6e-55 187.8 8.8 2.1 2 0 0 2 2 2 1 SPX domain EXS PF03124.14 EON98662.1 - 3.1e-14 53.1 13.1 5.9e-09 35.7 5.2 2.9 1 1 1 2 2 2 2 EXS family Cwf_Cwc_15 PF04889.12 EON98662.1 - 0.0037 17.1 10.5 0.0037 17.1 10.5 2.1 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein DUF883 PF05957.13 EON98662.1 - 0.13 12.9 1.0 0.49 11.0 0.8 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) RXT2_N PF08595.11 EON98662.1 - 6.3 6.8 10.9 4.2 7.4 1.1 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal AMP-binding PF00501.28 EON98664.1 - 1.3e-14 53.6 0.0 5.3e-08 31.9 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme zf-RanBP PF00641.18 EON98665.1 - 2.5e-18 65.1 13.3 8.6e-11 41.0 1.6 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 EON98665.1 - 3.2e-08 33.3 0.0 6.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 EON98665.1 - 8.7e-07 29.6 0.0 1.4e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease UQ_con PF00179.26 EON98666.1 - 4.1e-19 68.6 0.0 6.2e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EON98666.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 RWD domain PEP_mutase PF13714.6 EON98667.1 - 1.8e-42 145.5 0.4 2.5e-42 145.0 0.4 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase TFIID_NTD2 PF04494.15 EON98668.1 - 6.4e-41 139.6 0.3 8.9e-41 139.2 0.3 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 EON98668.1 - 3.4e-40 135.3 24.6 4.6e-07 30.4 0.4 7.1 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON98668.1 - 1.2e-11 44.8 0.1 0.061 13.6 0.0 5.5 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EON98668.1 - 1.6e-05 24.9 0.0 0.0017 18.2 0.0 3.4 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EON98668.1 - 0.0029 16.3 1.7 0.57 8.8 0.1 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EON98668.1 - 0.083 11.6 0.0 3.3 6.4 0.0 2.8 2 2 1 3 3 3 0 Nup133 N terminal like RAB3GAP2_N PF14655.6 EON98668.1 - 0.19 11.0 0.0 21 4.2 0.0 2.8 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ge1_WD40 PF16529.5 EON98668.1 - 2.8 6.8 4.2 15 4.5 1.0 3.3 2 2 3 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Torus PF16131.5 EON98669.1 - 2.6e-45 153.6 0.4 5.2e-45 152.6 0.0 1.7 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 EON98669.1 - 4.9e-08 32.7 0.0 9.4e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EON98669.1 - 0.00022 21.2 0.5 0.00022 21.2 0.5 1.9 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 EON98669.1 - 0.0025 17.7 0.8 0.0045 16.9 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 EON98669.1 - 0.081 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH_4 PF18044.1 EON98669.1 - 0.5 10.2 2.6 1.1 9.1 2.6 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger CAF1A PF12253.8 EON98670.1 - 1.9e-23 82.4 3.0 1.9e-23 82.4 3.0 2.9 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A Asp-B-Hydro_N PF05279.11 EON98670.1 - 3 7.9 24.3 7.1 6.6 24.3 1.6 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Spore_coat_CotO PF14153.6 EON98670.1 - 3.2 7.6 23.5 6.2 6.7 23.5 1.5 1 0 0 1 1 1 0 Spore coat protein CotO DUF913 PF06025.12 EON98670.1 - 4.2 6.3 7.8 8.6 5.2 7.8 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) WDCP PF15390.6 EON98670.1 - 9.7 4.4 13.6 17 3.6 13.6 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family MFS_1 PF07690.16 EON98671.1 - 3.4e-50 171.0 39.9 3.4e-47 161.1 42.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EON98671.1 - 7.1e-21 74.3 24.3 1.2e-20 73.5 24.3 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EON98671.1 - 3.9e-15 55.7 9.8 3.9e-15 55.7 9.8 2.7 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 EON98671.1 - 0.0056 15.6 10.1 0.0077 15.1 2.5 3.0 3 1 0 3 3 3 2 MFS_1 like family OATP PF03137.20 EON98671.1 - 3.6 5.8 13.9 11 4.1 11.2 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Cut12 PF11500.8 EON98672.1 - 1.3e-47 161.4 12.0 1.3e-47 161.4 12.0 4.3 3 1 3 6 6 6 1 Spindle pole body formation-associated protein Bacillus_HBL PF05791.11 EON98672.1 - 0.00072 19.4 1.6 0.00072 19.4 1.6 3.6 2 1 2 4 4 4 1 Bacillus haemolytic enterotoxin (HBL) TolA_bind_tri PF16331.5 EON98672.1 - 0.081 13.0 25.9 0.56 10.3 6.4 5.3 1 1 3 5 5 5 0 TolA binding protein trimerisation Fez1 PF06818.15 EON98672.1 - 0.24 11.8 56.9 0.3 11.5 19.3 3.3 1 1 2 3 3 3 0 Fez1 FUSC PF04632.12 EON98672.1 - 0.57 8.6 16.5 0.16 10.5 11.7 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family PKcGMP_CC PF16808.5 EON98672.1 - 4.3 7.3 12.4 7.9 6.4 0.5 4.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HMMR_N PF15905.5 EON98672.1 - 5.8 6.3 50.3 0.08 12.4 24.3 3.6 1 1 3 4 4 4 0 Hyaluronan mediated motility receptor N-terminal DUF2730 PF10805.8 EON98672.1 - 9.9 6.3 18.4 0.2 11.8 1.5 4.2 1 1 1 4 4 4 0 Protein of unknown function (DUF2730) ERG2_Sigma1R PF04622.12 EON98673.1 - 1.1e-99 332.0 0.1 1.3e-99 331.8 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein UCR_6-4kD PF08997.10 EON98673.1 - 0.085 12.8 0.0 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Fungal_trans_2 PF11951.8 EON98674.1 - 1e-05 24.5 3.4 0.00012 21.0 3.4 2.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain NPCC PF08058.11 EON98676.1 - 1.3e-09 38.2 0.0 1.5e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex component WD40 PF00400.32 EON98677.1 - 1.1e-26 92.5 10.0 2.2e-06 28.3 0.3 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 EON98677.1 - 7.8e-26 90.1 0.2 4.4e-25 87.7 0.3 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 EON98677.1 - 3.7e-06 27.2 0.7 0.041 14.2 0.1 4.2 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3759 PF12585.8 EON98678.1 - 5e-38 129.0 6.1 6.1e-38 128.7 6.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3824 PF12868.7 EON98678.1 - 0.058 14.1 1.5 0.1 13.3 1.5 1.5 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) Mor PF08765.11 EON98678.1 - 0.07 13.1 0.0 0.1 12.6 0.0 1.4 1 1 0 1 1 1 0 Mor transcription activator family AKAP_110 PF05716.13 EON98678.1 - 0.091 11.0 0.0 0.095 10.9 0.0 1.0 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) Vps5 PF09325.10 EON98679.1 - 1.4e-74 250.6 9.0 1.4e-74 250.6 9.0 1.4 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 EON98679.1 - 3.6e-25 88.2 0.4 8.3e-25 87.0 0.1 1.8 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 EON98679.1 - 0.0019 18.0 5.6 0.042 13.6 1.7 2.6 1 1 1 2 2 2 2 BAR domain of APPL family BAR_3_WASP_bdg PF10456.9 EON98679.1 - 0.0021 17.5 1.4 0.019 14.5 1.4 2.2 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein BAR_2 PF10455.9 EON98679.1 - 0.0059 15.8 7.1 0.0095 15.1 7.1 1.4 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Lipase_GDSL PF00657.22 EON98679.1 - 0.016 15.2 0.1 0.052 13.5 0.0 1.8 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase DUF3450 PF11932.8 EON98679.1 - 0.022 14.1 5.7 0.048 13.0 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) BAR PF03114.18 EON98679.1 - 0.12 12.0 9.2 0.29 10.7 9.2 1.8 1 1 0 1 1 1 0 BAR domain DUF713 PF05218.14 EON98679.1 - 0.26 11.0 5.4 0.17 11.6 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF713) Ebp2 PF05890.12 EON98680.1 - 1.5e-94 316.5 18.1 1.5e-94 316.5 18.1 3.1 1 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 EXOSC1 PF10447.9 EON98682.1 - 2.7e-21 76.2 3.6 2.1e-14 54.0 0.2 2.2 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EON98682.1 - 3.1e-12 46.1 0.0 6.7e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.23 EON98682.1 - 0.02 15.2 0.2 0.14 12.5 0.2 2.2 1 1 0 1 1 1 0 S1 RNA binding domain Acyl-CoA_dh_1 PF00441.24 EON98683.1 - 2.6e-28 99.1 0.9 3.9e-28 98.5 0.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON98683.1 - 1.7e-21 76.2 0.0 3e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EON98683.1 - 7.2e-14 52.4 0.0 2.3e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EON98683.1 - 1.1e-11 45.1 0.3 2e-11 44.3 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glyco_hydro_31 PF01055.26 EON98684.1 - 6.1e-143 477.2 3.8 8.9e-143 476.6 3.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EON98684.1 - 1.6e-22 79.6 0.4 2.4e-21 75.8 0.2 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EON98684.1 - 2.4e-07 30.9 1.4 7.6e-07 29.3 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) NDK PF00334.19 EON98685.1 - 3.4e-54 182.5 0.0 3.9e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NmrA PF05368.13 EON98686.1 - 3.5e-85 285.3 0.0 4.4e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EON98686.1 - 1.7e-07 31.4 0.3 3.9e-06 26.9 0.3 2.2 1 1 0 1 1 1 1 NAD(P)H-binding DUF3798 PF12683.7 EON98686.1 - 0.063 12.7 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) PSGP PF07276.11 EON98687.1 - 0.34 11.4 2.4 0.77 10.3 2.4 1.6 1 0 0 1 1 1 0 Apopolysialoglycoprotein (PSGP) p450 PF00067.22 EON98688.1 - 3.2e-31 108.6 0.0 2e-25 89.5 0.0 2.7 2 1 0 2 2 2 2 Cytochrome P450 Spo12 PF05032.12 EON98689.1 - 4.2e-16 58.6 1.3 5.5e-16 58.2 0.4 1.7 2 0 0 2 2 2 1 Spo12 family Flavin_Reduct PF01613.18 EON98690.1 - 3e-33 115.0 0.0 3.5e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain MS_channel PF00924.18 EON98691.1 - 3.5e-22 79.0 0.7 6.7e-22 78.1 0.7 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF2985 PF11204.8 EON98691.1 - 0.00029 20.9 1.5 0.062 13.5 0.1 3.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2985) DUF4349 PF14257.6 EON98691.1 - 0.01 15.3 0.3 0.8 9.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) EF-hand_7 PF13499.6 EON98691.1 - 0.063 13.7 0.4 0.32 11.5 0.2 2.2 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 EON98691.1 - 0.16 12.0 0.2 0.67 10.0 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 EON98691.1 - 0.26 10.9 1.1 0.86 9.3 0.5 2.2 2 0 0 2 2 2 0 EF hand ELO PF01151.18 EON98692.1 - 3.1e-63 213.6 17.3 3.6e-63 213.4 17.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DEAD PF00270.29 EON98693.1 - 8e-50 169.0 0.0 2.6e-49 167.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON98693.1 - 3.4e-32 111.1 0.0 8.7e-32 109.8 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON98693.1 - 0.0013 18.8 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EON98693.1 - 0.024 14.0 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MCM PF00493.23 EON98694.1 - 8e-106 352.2 0.1 5e-105 349.6 0.0 2.0 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EON98694.1 - 9e-36 122.5 0.2 1.8e-35 121.6 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EON98694.1 - 7.7e-28 96.8 1.0 1.8e-27 95.6 1.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EON98694.1 - 1.7e-15 57.5 0.6 4.4e-15 56.1 0.6 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EON98694.1 - 6.9e-07 28.9 0.0 0.00021 20.7 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EON98694.1 - 2e-05 24.6 0.0 4.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EON98694.1 - 0.00023 21.0 0.1 0.00097 19.0 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EON98694.1 - 0.058 13.1 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 EON98694.1 - 0.096 13.1 0.3 0.37 11.2 0.0 2.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Sugar_tr PF00083.24 EON98695.1 - 2.2e-87 293.8 25.8 2.5e-87 293.6 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON98695.1 - 2.7e-28 98.9 24.0 5.7e-28 97.9 20.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EON98695.1 - 1e-05 24.2 2.7 1e-05 24.2 2.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ost4 PF10215.9 EON98695.1 - 0.68 9.8 5.0 0.22 11.4 0.5 2.4 2 0 0 2 2 2 0 Oligosaccaryltransferase Laminin_I PF06008.14 EON98696.1 - 0.00034 20.4 12.1 0.00034 20.4 12.1 2.4 1 1 0 2 2 2 1 Laminin Domain I CENP-F_leu_zip PF10473.9 EON98696.1 - 0.00038 20.5 17.6 0.00038 20.5 17.6 3.6 1 1 3 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.6 EON98696.1 - 0.0023 17.7 7.3 0.0023 17.7 7.3 3.3 1 1 1 3 3 3 1 Domain of unknown function (DUF4201) AAA_13 PF13166.6 EON98696.1 - 0.0045 15.7 21.7 0.01 14.5 21.7 1.5 1 1 0 1 1 1 1 AAA domain TMF_TATA_bd PF12325.8 EON98696.1 - 0.015 15.5 12.6 0.015 15.5 12.6 4.5 3 1 2 5 5 4 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 EON98696.1 - 0.053 12.4 30.5 0.085 11.7 13.9 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein BRE1 PF08647.11 EON98696.1 - 0.14 12.3 25.3 0.49 10.5 7.7 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 EON98696.1 - 0.16 12.0 35.4 0.12 12.4 10.3 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 EON98696.1 - 0.19 11.3 29.0 0.75 9.3 10.7 3.0 1 1 1 3 3 3 0 Intermediate filament protein Osteoregulin PF07175.11 EON98696.1 - 0.25 11.5 6.5 0.57 10.4 6.5 1.6 1 0 0 1 1 1 0 Osteoregulin MAD PF05557.13 EON98696.1 - 0.26 9.6 27.8 0.39 9.0 27.8 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein CENP-K PF11802.8 EON98696.1 - 0.43 10.1 14.3 0.77 9.3 14.3 1.5 1 0 0 1 1 1 0 Centromere-associated protein K Flagellin_C PF00700.21 EON98696.1 - 0.44 10.9 5.5 0.69 10.3 0.3 3.0 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region DUF1664 PF07889.12 EON98696.1 - 0.61 10.1 15.6 4.4 7.4 0.2 3.8 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 EON98696.1 - 0.62 10.5 29.7 3.2 8.2 14.6 2.3 1 1 2 3 3 3 0 Fez1 Golgin_A5 PF09787.9 EON98696.1 - 0.68 9.4 31.6 2.3 7.6 7.0 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 FlaC_arch PF05377.11 EON98696.1 - 0.69 10.4 16.8 10 6.6 0.3 5.0 4 1 0 4 4 3 0 Flagella accessory protein C (FlaC) AAA_31 PF13614.6 EON98696.1 - 0.72 9.7 4.0 1 9.3 1.5 2.1 1 1 1 2 2 2 0 AAA domain NPV_P10 PF05531.12 EON98696.1 - 1.1 9.8 12.4 31 5.1 0.8 4.2 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 EON98696.1 - 1.2 9.2 20.0 0.65 10.0 8.7 3.3 1 1 2 3 3 3 0 Laminin Domain II YabA PF06156.13 EON98696.1 - 1.3 9.7 19.8 0.15 12.7 3.8 3.7 1 1 3 4 4 4 0 Initiation control protein YabA STAT_alpha PF01017.20 EON98696.1 - 1.3 8.9 15.4 1.9 8.3 4.6 2.5 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF3708 PF12501.8 EON98696.1 - 1.5 8.6 6.3 0.48 10.2 1.6 2.3 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter FPP PF05911.11 EON98696.1 - 1.8 6.6 25.8 0.084 11.1 5.6 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Shugoshin_N PF07558.11 EON98696.1 - 3.3 7.6 9.4 0.9 9.5 0.1 3.6 4 0 0 4 4 3 0 Shugoshin N-terminal coiled-coil region Baculo_PEP_C PF04513.12 EON98696.1 - 5.1 7.1 10.3 6.2 6.9 2.2 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 EON98696.1 - 5.9 7.3 20.5 1.3 9.3 6.0 4.0 3 1 1 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.11 EON98696.1 - 6.2 6.6 20.6 1 9.2 5.3 3.4 1 1 2 3 3 3 0 Phage minor structural protein GP20 LPP PF04728.13 EON98696.1 - 6.6 7.2 14.8 2.6 8.5 0.3 4.4 3 1 1 4 4 4 0 Lipoprotein leucine-zipper KASH_CCD PF14662.6 EON98696.1 - 8 6.2 26.8 10 5.9 8.1 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF3584 PF12128.8 EON98696.1 - 9.7 3.6 29.7 23 2.3 29.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DivIC PF04977.15 EON98696.1 - 9.9 6.0 30.8 1.2 9.0 3.6 4.9 3 1 2 5 5 5 0 Septum formation initiator WD40 PF00400.32 EON98697.1 - 4.5e-21 74.8 9.8 2.9e-05 24.8 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON98697.1 - 0.0054 17.0 0.0 0.25 11.7 0.0 3.2 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain SecY PF00344.20 EON98698.1 - 1e-70 238.5 7.9 1.3e-70 238.1 7.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EON98698.1 - 1.1e-17 63.5 0.3 3.2e-17 62.1 0.3 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p Hid1 PF12722.7 EON98699.1 - 1e-185 619.3 2.5 1.4e-101 341.0 0.2 2.0 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EON98699.1 - 6.5e-68 229.7 0.0 5.3e-35 120.9 0.0 2.0 1 1 1 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein zf-C2H2_4 PF13894.6 EON98700.1 - 6.9e-08 32.7 22.9 0.069 14.0 0.3 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 EON98700.1 - 7.9e-05 22.9 21.6 0.049 14.1 0.5 4.9 5 0 0 5 5 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EON98700.1 - 0.0019 18.1 22.7 0.024 14.7 0.8 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EON98700.1 - 0.016 15.3 8.1 0.92 9.7 0.3 3.3 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 EON98700.1 - 0.082 12.8 3.3 2.7 7.9 0.1 3.7 3 1 0 3 3 3 0 C2H2 type zinc-finger (1 copy) CpXC PF14353.6 EON98700.1 - 0.11 12.5 6.4 1.2 9.2 0.5 3.4 3 1 0 3 3 3 0 CpXC protein DUF4965 PF16335.5 EON98700.1 - 0.12 12.0 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4965) zf-C2H2_jaz PF12171.8 EON98700.1 - 0.34 11.3 8.3 0.72 10.2 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EON98700.1 - 0.49 10.9 16.1 1.4 9.4 1.4 3.8 3 0 0 3 3 3 0 Zinc-finger double domain OrfB_Zn_ribbon PF07282.11 EON98700.1 - 0.64 10.0 3.1 20 5.2 0.4 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-C2H2_11 PF16622.5 EON98700.1 - 0.92 9.3 3.3 24 4.8 0.2 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-ribbon_3 PF13248.6 EON98700.1 - 2 7.9 8.3 3.2 7.3 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain zf-Mss51 PF13824.6 EON98700.1 - 2.8 8.1 13.0 6.6 6.9 2.3 3.1 3 1 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 COX5A PF02284.16 EON98701.1 - 1.3e-40 137.6 0.0 1.6e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va UQ_con PF00179.26 EON98702.1 - 3.1e-39 133.8 0.0 4.1e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EON98702.1 - 8.4e-06 25.5 0.1 1.5e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 EON98702.1 - 0.0029 17.3 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EON98702.1 - 0.0078 16.1 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 UEV domain Aldo_ket_red PF00248.21 EON98703.1 - 1.8e-67 227.6 0.0 2.4e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family LysM PF01476.20 EON98703.1 - 9e-12 44.9 0.0 2.8e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 LysM domain Actino_peptide PF14408.6 EON98703.1 - 0.059 13.5 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomally synthesised peptide in actinomycetes Phage_tail_X PF05489.12 EON98703.1 - 0.11 12.2 0.0 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Phage Tail Protein X Fungal_trans PF04082.18 EON98704.1 - 9.3e-10 38.0 1.6 3e-09 36.3 1.6 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain TPR_2 PF07719.17 EON98705.1 - 1.2e-08 34.4 5.1 0.0016 18.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EON98705.1 - 3.9e-06 26.6 0.9 0.021 15.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EON98705.1 - 1.6e-05 24.5 1.6 0.43 10.5 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EON98705.1 - 0.00048 20.4 0.6 0.92 9.8 0.1 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EON98705.1 - 0.00076 20.1 2.1 0.04 14.6 0.5 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EON98705.1 - 0.0019 18.7 0.0 0.072 13.6 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat HCR PF07111.12 EON98705.1 - 0.029 12.4 0.0 0.045 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) TPR_11 PF13414.6 EON98705.1 - 0.044 13.5 0.8 2.8 7.7 0.5 3.2 3 0 0 3 3 3 0 TPR repeat Methyltransf_25 PF13649.6 EON98706.1 - 1.1e-14 54.8 0.0 5.8e-14 52.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON98706.1 - 2.2e-11 44.3 0.0 7.9e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON98706.1 - 7.5e-09 35.6 0.0 2e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON98706.1 - 2.9e-07 31.1 0.0 1.1e-06 29.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON98706.1 - 3.3e-07 30.2 0.0 8.7e-06 25.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EON98706.1 - 0.00055 19.5 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain OPT PF03169.15 EON98707.1 - 1.3e-87 294.9 42.6 1.5e-87 294.8 42.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ribonuclease_T2 PF00445.18 EON98708.1 - 1.7e-24 87.1 0.0 2.1e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family SNF2_N PF00176.23 EON98709.1 - 8.3e-66 222.1 0.4 1.8e-65 221.0 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 EON98709.1 - 1.6e-47 161.2 16.5 1.6e-47 161.2 16.5 4.9 4 1 1 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 EON98709.1 - 2.3e-20 73.0 0.0 5.8e-20 71.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON98709.1 - 9.9e-06 25.7 0.0 9.9e-06 25.7 0.0 3.4 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit Chalcone_2 PF16035.5 EON98710.1 - 4.9e-79 264.8 0.1 6.5e-79 264.5 0.1 1.1 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone PF02431.15 EON98710.1 - 0.00019 20.9 0.0 0.13 11.7 0.0 2.1 2 0 0 2 2 2 2 Chalcone-flavanone isomerase Chalcone_3 PF16036.5 EON98710.1 - 0.00022 21.4 0.1 0.087 12.9 0.1 2.2 1 1 1 2 2 2 2 Chalcone isomerase-like UCR_Fe-S_N PF10399.9 EON98710.1 - 0.015 14.6 1.0 0.037 13.4 0.0 2.1 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAT_signal PF10518.9 EON98710.1 - 0.08 12.8 0.4 0.08 12.8 0.4 1.8 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence RAI16-like PF10257.9 EON98712.1 - 1.1e-55 189.0 0.2 1.5e-55 188.5 0.2 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Clr5 PF14420.6 EON98713.1 - 4.1e-07 30.1 0.4 6.5e-07 29.5 0.1 1.4 2 0 0 2 2 2 1 Clr5 domain HD PF01966.22 EON98714.1 - 6e-05 23.3 0.0 8.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 HD domain UCH_C PF18031.1 EON98715.1 - 0.0088 15.9 1.1 0.031 14.2 1.1 1.9 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Sdh_cyt PF01127.22 EON98715.1 - 2.4 8.2 8.0 4.7 7.3 8.0 1.4 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 4HBT_2 PF13279.6 EON98717.1 - 8e-22 78.0 0.2 1.2e-21 77.5 0.2 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily eIF3_N PF09440.10 EON98717.1 - 0.00097 19.6 0.5 0.0015 19.0 0.5 1.2 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain Lipase_3 PF01764.25 EON98718.1 - 2.5e-19 69.5 0.0 4.7e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EON98718.1 - 0.0013 19.3 0.1 0.0019 18.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 EON98718.1 - 0.013 15.0 0.1 4 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) X PF00739.19 EON98718.1 - 0.032 14.4 1.8 0.038 14.1 0.5 1.9 2 0 0 2 2 2 0 Trans-activation protein X FAD_binding_4 PF01565.23 EON98719.1 - 1.4e-20 73.5 4.0 1.4e-20 73.5 4.0 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EON98719.1 - 2.7e-12 46.6 0.0 5.2e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like TRI12 PF06609.13 EON98720.1 - 9.4e-62 209.3 23.7 1.2e-61 208.9 23.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EON98720.1 - 2.6e-24 85.8 43.0 6.5e-23 81.2 38.4 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON98720.1 - 2.3e-12 46.5 11.9 2.3e-12 46.5 11.9 3.5 2 1 2 4 4 4 1 Sugar (and other) transporter Ank_2 PF12796.7 EON98721.1 - 1.5e-28 99.2 0.0 3.7e-10 40.3 0.0 4.1 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EON98721.1 - 1e-20 73.8 0.0 9.5e-09 35.6 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EON98721.1 - 5e-15 55.2 0.0 0.004 17.6 0.0 6.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 EON98721.1 - 1e-13 50.1 0.3 0.028 14.9 0.0 6.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 EON98721.1 - 3.5e-13 49.5 0.1 0.0013 19.0 0.0 5.5 3 2 1 5 5 5 4 Ankyrin repeats (many copies) TPR_12 PF13424.6 EON98721.1 - 0.00032 20.9 0.2 0.00087 19.5 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat CdvA PF18822.1 EON98721.1 - 0.00048 20.0 0.1 0.0016 18.2 0.1 2.0 1 0 0 1 1 1 1 CdvA-like coiled-coil domain TPR_2 PF07719.17 EON98721.1 - 0.0014 18.5 2.2 0.0039 17.2 0.4 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EON98721.1 - 0.0037 17.1 0.5 0.012 15.4 0.5 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EON98721.1 - 0.0056 16.8 1.5 0.024 14.8 0.1 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat Helo_like_N PF17111.5 EON98721.1 - 0.013 14.9 0.2 0.03 13.7 0.2 1.6 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins TPR_1 PF00515.28 EON98721.1 - 0.014 15.2 1.0 0.039 13.8 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EON98721.1 - 0.04 13.6 0.2 0.69 9.7 0.0 2.5 2 0 0 2 2 2 0 TPR repeat TPR_MalT PF17874.1 EON98721.1 - 0.18 11.1 1.3 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 MalT-like TPR region TPR_14 PF13428.6 EON98721.1 - 0.68 10.9 2.2 1.6 9.7 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Snapin_Pallidin PF14712.6 EON98721.1 - 1.7 9.1 6.1 12 6.4 0.2 3.9 3 1 1 5 5 4 0 Snapin/Pallidin MPC PF03650.13 EON98722.1 - 8.3e-34 116.0 0.0 1.1e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Sod_Fe_C PF02777.18 EON98723.1 - 2.6e-36 123.8 0.9 3.5e-36 123.5 0.1 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EON98723.1 - 1.9e-19 69.9 4.9 3.1e-19 69.2 2.7 2.1 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Zn_clus PF00172.18 EON98724.1 - 0.067 13.3 6.9 0.14 12.3 6.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF89 PF01937.19 EON98725.1 - 8.8e-109 363.7 0.1 2.8e-108 362.0 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function DUF89 BAG PF02179.16 EON98726.1 - 3.4e-21 75.5 0.6 7.7e-21 74.3 0.6 1.6 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 EON98726.1 - 2.2e-05 24.1 0.0 4.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 EON98726.1 - 0.0041 17.5 0.1 0.01 16.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EON98726.1 - 0.041 13.9 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD PF11976.8 EON98726.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EON98726.1 - 0.15 12.6 1.5 0.35 11.4 1.5 1.6 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Acyltransferase PF01553.21 EON98727.1 - 8.7e-27 93.4 0.0 2.2e-26 92.1 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 EON98727.1 - 4e-13 49.3 0.3 6.9e-13 48.5 0.3 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus NAD_kinase PF01513.21 EON98728.1 - 4.5e-52 177.0 0.0 1.6e-51 175.2 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EON98728.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Glyco_hydro_64 PF16483.5 EON98729.1 - 1.2e-135 452.5 0.0 1.4e-135 452.3 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Radical_SAM_C PF16199.5 EON98730.1 - 5.3e-32 109.7 0.0 1e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EON98730.1 - 1.1e-16 61.7 0.0 3.7e-16 59.9 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EON98730.1 - 1.1e-08 35.4 0.1 2e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EON98730.1 - 4.4e-06 26.7 0.0 9.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EON98730.1 - 0.02 15.3 0.0 0.045 14.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ytp1 PF10355.9 EON98731.1 - 1.9e-69 233.9 26.1 2.5e-69 233.6 19.4 2.6 2 1 0 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EON98731.1 - 7.3e-24 83.6 2.9 7.3e-24 83.6 2.9 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) CoA_binding PF02629.19 EON98733.1 - 7.9e-26 90.6 3.4 9.4e-26 90.3 0.8 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EON98733.1 - 1.1e-23 83.7 0.3 1.7e-23 83.1 0.3 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EON98733.1 - 8.4e-10 38.6 0.1 1.4e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EON98733.1 - 0.00039 20.9 0.0 0.001 19.5 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Ysc84 PF04366.12 EON98734.1 - 1.3e-50 170.5 0.0 2e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator ALMT PF11744.8 EON98734.1 - 0.22 10.3 0.6 0.32 9.8 0.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MBR1 PF17058.5 EON98734.1 - 0.43 10.8 7.9 0.76 10.0 7.9 1.3 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 3Beta_HSD PF01073.19 EON98735.1 - 5.7e-48 163.3 0.0 6.9e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EON98735.1 - 9.9e-32 110.3 0.0 1.3e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EON98735.1 - 1.6e-13 50.7 0.0 2e-12 47.2 0.0 2.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EON98735.1 - 1.4e-12 47.9 0.1 2.3e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EON98735.1 - 1.5e-12 47.2 0.0 6.3e-09 35.4 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EON98735.1 - 2.8e-11 43.0 0.1 3.7e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EON98735.1 - 3.8e-09 36.7 0.1 1.3e-08 35.0 0.1 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EON98735.1 - 4.7e-07 29.2 0.4 3.3e-06 26.5 0.4 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EON98735.1 - 0.00074 19.1 0.2 0.0012 18.5 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family FtsJ PF01728.19 EON98735.1 - 0.029 14.5 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase FIST_C PF10442.9 EON98735.1 - 0.079 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 FIST C domain Glyco_hydro_72 PF03198.14 EON98736.1 - 5.1e-123 410.3 3.3 6.6e-123 410.0 3.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EON98736.1 - 2.4e-20 73.0 4.2 6.7e-20 71.6 4.2 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 EON98736.1 - 1.2e-05 24.6 0.2 4.9e-05 22.6 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain CFC PF09443.10 EON98736.1 - 0.14 12.0 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) Lactonase PF10282.9 EON98737.1 - 4.8e-65 220.1 0.0 5.5e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller LVIVD PF08309.11 EON98737.1 - 0.051 12.9 0.3 0.11 11.8 0.1 1.7 2 0 0 2 2 2 0 LVIVD repeat Glutaredoxin PF00462.24 EON98738.1 - 7.8e-21 74.1 0.0 1.1e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EON98738.1 - 0.0058 17.0 0.0 0.0074 16.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 EON98738.1 - 0.006 17.0 0.1 0.0094 16.3 0.1 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 EON98738.1 - 0.012 15.4 0.1 0.41 10.4 0.2 2.1 1 1 0 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 EON98738.1 - 0.015 15.7 0.1 0.032 14.7 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_4 PF13462.6 EON98738.1 - 0.02 15.1 1.0 3.9 7.6 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin TraF PF13728.6 EON98738.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Cerato-platanin PF07249.12 EON98739.1 - 2.1e-53 179.5 0.7 2.5e-53 179.2 0.7 1.0 1 0 0 1 1 1 1 Cerato-platanin Phage_holin_3_1 PF05106.12 EON98739.1 - 0.048 14.1 0.4 2.7 8.5 0.1 2.1 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) NAD_binding_8 PF13450.6 EON98740.1 - 3.8e-10 39.9 0.1 6.9e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EON98740.1 - 1.1e-06 28.2 0.0 0.01 15.2 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EON98740.1 - 0.00061 18.6 1.3 0.00081 18.2 0.5 1.5 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EON98740.1 - 0.00071 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EON98740.1 - 0.00091 18.7 0.1 0.0016 17.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON98740.1 - 0.0017 17.6 1.0 0.0032 16.8 0.6 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON98740.1 - 0.0043 17.6 3.2 0.015 15.9 1.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON98740.1 - 0.0049 16.0 2.6 0.0072 15.5 2.6 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EON98740.1 - 0.01 14.9 1.0 0.059 12.4 1.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 EON98740.1 - 0.058 13.6 0.2 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 EON98740.1 - 0.072 12.7 0.9 0.14 11.8 0.9 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 EON98740.1 - 0.24 10.6 1.0 0.38 10.0 1.0 1.3 1 0 0 1 1 1 0 FAD binding domain Aa_trans PF01490.18 EON98742.1 - 2.8e-29 102.1 35.1 4.6e-29 101.4 35.1 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Exo_endo_phos PF03372.23 EON98743.1 - 3.5e-19 69.2 0.2 4.4e-18 65.7 0.2 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 EON98743.1 - 0.13 12.8 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) LIDHydrolase PF10230.9 EON98744.1 - 1.1e-55 189.1 0.0 1.2e-55 188.9 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 EON98744.1 - 0.0027 18.4 1.2 0.0043 17.7 1.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON98744.1 - 0.011 15.1 0.1 0.044 13.0 0.1 1.9 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EON98744.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold AA_permease_2 PF13520.6 EON98745.1 - 1.1e-49 169.5 44.2 1.2e-49 169.3 44.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EON98745.1 - 2e-16 59.7 39.7 2.7e-16 59.3 39.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4293 PF14126.6 EON98745.1 - 0.12 12.6 0.2 0.12 12.6 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) SID-1_RNA_chan PF13965.6 EON98745.1 - 0.33 9.3 1.9 0.75 8.1 1.9 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Draxin PF15550.6 EON98746.1 - 2.2 8.1 12.0 2.6 7.8 12.0 1.0 1 0 0 1 1 1 0 Draxin Ribosomal_L13 PF00572.18 EON98747.1 - 4.5e-12 46.3 0.0 4.6e-10 39.8 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.20 EON98747.1 - 0.031 14.0 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain GFO_IDH_MocA PF01408.22 EON98748.1 - 2.7e-21 76.6 0.1 6.8e-21 75.3 0.1 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EON98748.1 - 1.5e-13 50.8 0.0 2.6e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EON98748.1 - 9.9e-07 29.4 0.0 2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 EON98748.1 - 0.16 12.5 0.0 0.34 11.4 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain AAA PF00004.29 EON98749.1 - 4e-41 140.5 0.0 7.6e-41 139.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EON98749.1 - 1.1e-11 44.4 0.2 2.5e-11 43.4 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EON98749.1 - 9e-11 41.4 0.9 1.7e-10 40.5 0.9 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EON98749.1 - 1.7e-06 28.2 0.0 3.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EON98749.1 - 5.5e-06 26.7 0.2 0.0056 17.0 0.2 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EON98749.1 - 1.1e-05 24.7 0.0 1.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EON98749.1 - 8.9e-05 22.5 0.1 0.0003 20.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EON98749.1 - 0.00026 20.8 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EON98749.1 - 0.00027 21.4 0.2 0.0033 17.8 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EON98749.1 - 0.00069 20.2 0.0 0.0015 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 EON98749.1 - 0.001 18.6 0.7 0.0059 16.2 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 EON98749.1 - 0.0028 17.9 0.6 0.0074 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EON98749.1 - 0.0069 16.5 0.0 0.026 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EON98749.1 - 0.012 15.5 0.1 0.62 10.0 0.1 2.6 2 1 1 3 3 2 0 NACHT domain AAA_3 PF07726.11 EON98749.1 - 0.018 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EON98749.1 - 0.018 15.0 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EON98749.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 EON98749.1 - 0.02 14.3 1.9 0.51 9.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein TIP49 PF06068.13 EON98749.1 - 0.027 13.7 0.9 0.07 12.3 0.1 1.9 2 1 0 2 2 2 0 TIP49 P-loop domain ATPase PF06745.13 EON98749.1 - 0.031 13.6 0.1 0.5 9.7 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 EON98749.1 - 0.052 13.9 0.0 0.097 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EON98749.1 - 0.061 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EON98749.1 - 0.068 12.4 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin WYL PF13280.6 EON98749.1 - 0.1 12.6 0.1 0.85 9.7 0.0 2.1 2 0 0 2 2 2 0 WYL domain DUF2075 PF09848.9 EON98749.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 EON98749.1 - 0.23 11.2 1.8 0.29 10.8 0.3 2.0 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EON98749.1 - 1.3 8.6 5.1 0.55 9.8 0.4 2.6 2 1 0 3 3 2 0 AAA domain Promethin PF16015.5 EON98753.1 - 5.7e-31 106.6 15.8 6.9e-31 106.3 15.8 1.1 1 0 0 1 1 1 1 Promethin CFEM PF05730.11 EON98754.1 - 1.8e-11 44.0 18.2 6.5e-11 42.2 18.2 2.0 1 0 0 1 1 1 1 CFEM domain ABC_tran PF00005.27 EON98755.1 - 3.3e-45 154.0 0.0 2.6e-21 76.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EON98755.1 - 2.8e-21 75.3 3.2 2.8e-21 75.3 3.2 3.0 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 EON98755.1 - 1.2e-17 64.7 0.6 0.00051 19.9 0.0 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON98755.1 - 1.8e-12 47.2 0.1 0.00023 20.7 0.0 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EON98755.1 - 4.2e-08 32.8 0.2 0.0033 17.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EON98755.1 - 2e-07 31.7 6.9 0.046 14.2 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_15 PF13175.6 EON98755.1 - 8.7e-07 29.0 0.0 0.05 13.3 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.6 EON98755.1 - 1.9e-06 28.3 0.0 0.0056 17.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EON98755.1 - 2.5e-06 27.5 0.2 0.0078 16.1 0.0 3.0 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 EON98755.1 - 7.5e-06 26.3 0.0 0.087 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EON98755.1 - 8.5e-06 26.3 0.1 0.095 13.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 EON98755.1 - 1.3e-05 25.2 0.1 0.02 15.0 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EON98755.1 - 6.9e-05 23.1 0.0 0.035 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EON98755.1 - 0.00015 22.1 1.0 1.1 9.7 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA PF00004.29 EON98755.1 - 0.0002 21.8 0.0 1.2 9.6 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EON98755.1 - 0.00031 20.9 0.0 0.15 12.2 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EON98755.1 - 0.00034 20.6 0.2 1.1 9.3 0.2 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_27 PF13514.6 EON98755.1 - 0.00039 20.1 0.0 0.13 11.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EON98755.1 - 0.00059 19.8 0.4 0.94 9.4 0.0 2.8 2 0 0 2 2 2 2 NACHT domain NB-ARC PF00931.22 EON98755.1 - 0.0012 18.1 0.2 1.4 8.1 0.0 3.3 2 1 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 EON98755.1 - 0.0025 17.6 2.3 1.9 8.2 0.1 3.5 4 0 0 4 4 4 1 AAA domain Roc PF08477.13 EON98755.1 - 0.0036 17.5 0.1 2.7 8.3 0.1 3.2 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EON98755.1 - 0.004 17.2 0.0 3.7 7.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EON98755.1 - 0.014 14.9 0.0 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_17 PF13207.6 EON98755.1 - 0.02 15.3 0.0 3.7 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EON98755.1 - 0.031 14.0 0.3 5 6.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF2813 PF11398.8 EON98755.1 - 0.031 13.6 0.1 9.2 5.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) NTPase_1 PF03266.15 EON98755.1 - 0.044 13.7 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 NTPase DUF87 PF01935.17 EON98755.1 - 0.051 13.7 0.3 14 5.7 0.0 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain DUF815 PF05673.13 EON98755.1 - 0.073 12.2 0.1 2.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 EON98755.1 - 0.08 12.5 0.1 1.1 8.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 EON98755.1 - 0.097 12.4 0.7 4.3 7.1 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.25 EON98755.1 - 0.1 12.2 0.0 0.51 9.9 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 EON98755.1 - 0.2 11.7 0.5 23 5.0 0.0 3.1 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sulfotransfer_4 PF17784.1 EON98756.1 - 3.4e-57 193.7 0.0 4.2e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EON98756.1 - 0.0015 18.9 0.1 1.4 9.3 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family DNApol_Exo PF18136.1 EON98756.1 - 0.082 12.0 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain p450 PF00067.22 EON98757.1 - 1.6e-06 27.2 0.0 1.8e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Dabb PF07876.12 EON98758.1 - 2.1e-08 34.7 0.0 2.7e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain SAICAR_synt PF01259.18 EON98759.1 - 8.2e-101 336.8 0.0 9.7e-101 336.6 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase DUF3253 PF11625.8 EON98759.1 - 0.087 13.1 0.0 3.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) YIF1 PF03878.15 EON98760.1 - 1.1e-98 329.5 5.2 1.3e-98 329.3 5.2 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EON98760.1 - 6.7e-05 22.7 8.8 6.7e-05 22.7 8.8 1.6 2 0 0 2 2 2 1 Yip1 domain p450 PF00067.22 EON98761.1 - 2.5e-43 148.5 0.0 3.3e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hydrolase_6 PF13344.6 EON98762.1 - 2.1e-23 82.4 0.0 4.5e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EON98762.1 - 1.5e-15 57.0 0.0 5e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EON98762.1 - 0.0035 17.7 0.0 3 8.1 0.0 3.1 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EON98762.1 - 0.019 15.1 0.1 1.9 8.5 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 EON98763.1 - 5.4e-14 51.9 20.4 5.4e-14 51.9 20.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON98763.1 - 0.00024 20.1 9.6 0.00035 19.6 9.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON98764.1 - 6.6e-36 124.0 34.6 3.6e-32 111.7 28.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON98764.1 - 1.3e-06 27.6 5.0 1.3e-06 27.6 5.0 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EON98764.1 - 1.1 8.1 10.0 2 7.2 7.3 2.9 2 1 0 2 2 2 0 MFS_1 like family MoaE PF02391.17 EON98765.1 - 3.2e-38 130.5 0.0 3.9e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 MoaE protein Pkinase PF00069.25 EON98766.1 - 2.9e-60 203.9 0.0 3.3e-59 200.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON98766.1 - 1.5e-28 99.8 0.5 1.2e-19 70.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EON98766.1 - 3.3e-05 24.5 2.0 3.3e-05 24.5 2.0 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain APH PF01636.23 EON98766.1 - 0.0047 16.9 0.1 0.11 12.4 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EON98766.1 - 0.0054 16.1 0.2 0.026 13.9 0.0 2.1 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 EON98766.1 - 0.032 13.6 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EON98766.1 - 0.036 13.0 0.0 0.06 12.3 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain tRNA-synt_1b PF00579.25 EON98767.1 - 6.8e-46 156.9 0.0 8.8e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HATPase_c PF02518.26 EON98769.1 - 1.3e-21 77.2 0.0 3.1e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EON98769.1 - 3.4e-19 69.1 0.8 1.5e-18 67.0 0.1 2.5 2 0 0 2 2 2 1 Response regulator receiver domain PAS_9 PF13426.7 EON98769.1 - 7.5e-09 35.8 0.0 0.0034 17.6 0.0 3.3 2 1 0 2 2 2 2 PAS domain HisKA PF00512.25 EON98769.1 - 1.8e-08 34.3 3.4 9e-08 32.0 0.0 3.2 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 EON98769.1 - 5e-08 33.1 0.0 0.013 15.7 0.0 3.5 2 1 0 2 2 2 2 PAS fold PAS PF00989.25 EON98769.1 - 4e-06 26.8 0.0 0.03 14.3 0.0 3.0 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 EON98769.1 - 5.3e-06 26.3 0.0 0.0056 16.7 0.0 3.3 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 EON98769.1 - 1.1e-05 25.6 0.0 0.031 14.5 0.0 4.3 4 0 0 4 4 4 1 PAS fold HATPase_c_3 PF13589.6 EON98769.1 - 0.11 12.3 0.1 0.71 9.7 0.1 2.3 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Choline_kinase PF01633.20 EON98770.1 - 8.6e-64 215.0 0.0 1.4e-63 214.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 EON98770.1 - 1.3e-19 69.6 0.0 2.4e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 EON98770.1 - 2.3e-05 24.5 0.7 7.9e-05 22.7 0.1 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family DFP PF04127.15 EON98772.1 - 8.8e-14 51.8 0.0 5.2e-06 26.4 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein SCO1-SenC PF02630.14 EON98773.1 - 1e-50 171.1 0.1 1.4e-50 170.7 0.1 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EON98773.1 - 0.0025 17.7 0.0 0.0063 16.4 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EON98773.1 - 0.0042 17.4 0.0 0.008 16.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EON98773.1 - 0.017 14.8 0.0 0.35 10.6 0.0 2.2 1 1 0 1 1 1 0 Redoxin MetallophosN PF16371.5 EON98773.1 - 0.77 10.1 2.2 17 5.8 0.1 2.8 3 0 0 3 3 3 0 N terminal of Calcineurin-like phosphoesterase PHD PF00628.29 EON98774.1 - 8.1e-11 41.7 6.4 1.8e-10 40.6 6.4 1.6 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 EON98774.1 - 0.066 13.3 5.5 0.16 12.1 5.5 1.7 1 0 0 1 1 1 0 PHD-finger BTB PF00651.31 EON98775.1 - 9.1e-12 45.2 0.7 1.2e-10 41.6 0.6 2.2 2 0 0 2 2 2 1 BTB/POZ domain HTH_33 PF13592.6 EON98775.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix FMO-like PF00743.19 EON98776.1 - 3.5e-17 62.0 0.1 3.6e-14 52.1 0.0 2.6 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EON98776.1 - 1.6e-14 53.8 0.0 8.8e-13 48.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON98776.1 - 4.1e-10 39.4 0.0 1.8e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON98776.1 - 2.1e-09 37.0 0.0 9.3e-09 34.9 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EON98776.1 - 1.4e-07 31.6 0.0 5.4e-06 26.6 0.0 3.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EON98776.1 - 0.0024 18.4 1.3 2.6 8.7 0.2 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON98776.1 - 0.0035 16.5 0.0 0.0058 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EON98776.1 - 0.004 16.8 0.1 0.41 10.2 0.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EON98776.1 - 0.0088 16.0 2.2 8.3 6.4 0.0 4.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EON98776.1 - 0.026 13.6 0.1 0.069 12.2 0.1 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 EON98776.1 - 0.04 12.6 0.7 0.21 10.3 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EON98776.1 - 0.051 12.8 0.3 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 EON98776.1 - 0.14 12.2 0.0 20 5.3 0.0 2.6 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase Lipase_GDSL_2 PF13472.6 EON98777.1 - 1.1e-10 42.3 3.9 2.1e-10 41.3 3.9 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EON98777.1 - 3.2e-09 37.0 0.6 6.3e-09 36.1 0.6 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase VirDNA-topo-I_N PF09266.10 EON98777.1 - 0.035 14.3 0.0 0.82 9.9 0.0 2.5 2 0 0 2 2 2 0 Viral DNA topoisomerase I, N-terminal Amidase PF01425.21 EON98778.1 - 2.5e-64 217.9 2.6 3.4e-64 217.5 2.6 1.2 1 0 0 1 1 1 1 Amidase DUF1752 PF08550.10 EON98779.1 - 1.4e-11 44.0 0.6 2.6e-11 43.1 0.6 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Polyketide_cyc2 PF10604.9 EON98780.1 - 7.8e-05 23.0 0.4 0.0023 18.2 0.4 2.2 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Pkinase PF00069.25 EON98782.1 - 1.9e-52 178.3 0.0 8.6e-35 120.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EON98782.1 - 6e-35 120.8 0.0 6.6e-34 117.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EON98782.1 - 0.0017 17.7 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EON98782.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF3896 PF13035.6 EON98782.1 - 0.22 11.7 0.1 0.22 11.7 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3896) Filament PF00038.21 EON98782.1 - 3.5 7.1 15.9 0.38 10.3 11.4 1.5 2 0 0 2 2 2 0 Intermediate filament protein ketoacyl-synt PF00109.26 EON98783.1 - 3e-74 249.8 0.0 5.9e-74 248.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EON98783.1 - 1.6e-60 204.1 0.1 3.2e-60 203.1 0.1 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EON98783.1 - 1.2e-51 176.2 0.1 5.3e-51 174.0 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.6 EON98783.1 - 1.8e-44 152.2 0.0 2.8e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EON98783.1 - 2.5e-36 124.2 0.0 5.3e-36 123.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EON98783.1 - 3e-13 49.7 0.0 6.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 EON98783.1 - 9.1e-08 32.1 0.0 4e-07 30.1 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EON98783.1 - 1e-05 25.8 0.1 2.9e-05 24.3 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EON98783.1 - 0.0004 19.8 0.1 0.00097 18.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ThiF PF00899.21 EON98783.1 - 0.18 11.2 0.2 0.35 10.2 0.2 1.4 1 0 0 1 1 1 0 ThiF family Asp PF00026.23 EON98784.1 - 5.2e-59 200.2 2.6 7.5e-59 199.7 2.6 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EON98784.1 - 1.4e-10 41.7 1.1 5.2e-09 36.6 1.1 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EON98784.1 - 0.00053 20.6 3.1 1.4 9.6 0.1 3.8 2 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EON98784.1 - 0.42 11.2 1.8 11 6.6 0.1 3.6 4 1 0 4 4 4 0 gag-polyprotein putative aspartyl protease OPT PF03169.15 EON98785.1 - 2e-175 585.0 51.1 2.3e-175 584.8 51.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein G-patch PF01585.23 EON98786.1 - 2.2e-10 40.2 1.5 8.3e-10 38.4 0.6 2.2 2 0 0 2 2 2 1 G-patch domain zf-C2H2_jaz PF12171.8 EON98786.1 - 0.00014 22.1 0.2 0.88 9.9 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding RRM_1 PF00076.22 EON98786.1 - 0.00017 21.3 0.0 0.00062 19.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 EON98786.1 - 0.00021 21.3 3.2 0.00071 19.6 3.2 2.0 1 0 0 1 1 1 1 G-patch domain zf-C2H2_4 PF13894.6 EON98786.1 - 0.0058 17.4 0.8 1.3 10.1 0.1 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 EON98786.1 - 0.0094 16.3 0.7 1.8 9.1 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EON98786.1 - 0.0095 16.3 2.4 1.9 8.9 0.1 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) MT0933_antitox PF14013.6 EON98786.1 - 0.019 15.3 1.3 0.019 15.3 1.3 2.2 2 0 0 2 2 2 0 MT0933-like antitoxin protein RED_N PF07808.13 EON98786.1 - 0.026 14.1 0.9 0.026 14.1 0.9 2.4 2 0 0 2 2 2 0 RED-like protein N-terminal region zf-C2H2 PF00096.26 EON98786.1 - 0.1 13.1 1.0 21 5.8 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 EON98786.1 - 0.11 12.3 0.1 15 5.4 0.1 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 EON98786.1 - 0.13 12.7 0.1 20 5.8 0.1 2.6 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Mpv17_PMP22 PF04117.12 EON98787.1 - 3.8e-12 46.3 0.1 6.9e-12 45.4 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.16 EON98789.1 - 1.4e-21 76.8 44.0 1.2e-14 54.1 31.0 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EON98789.1 - 2.5e-07 29.5 18.7 8.3e-07 27.8 18.1 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ca_hom_mod PF14798.6 EON98789.1 - 0.03 13.4 1.7 0.42 9.7 0.2 2.5 2 0 0 2 2 2 0 Calcium homeostasis modulator Pox_A14 PF05767.12 EON98789.1 - 0.12 12.6 0.1 0.12 12.6 0.1 4.1 4 1 1 5 5 5 0 Poxvirus virion envelope protein A14 SRP-alpha_N PF04086.13 EON98790.1 - 3.4e-73 247.1 0.4 4.5e-73 246.7 0.4 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 EON98790.1 - 1.9e-53 181.0 0.2 3.2e-53 180.3 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EON98790.1 - 5.6e-08 32.9 0.1 1.8e-07 31.3 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EON98790.1 - 2.9e-06 26.5 0.1 5.4e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EON98790.1 - 0.00076 19.3 0.1 0.0018 18.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EON98790.1 - 0.00078 19.9 0.4 0.01 16.2 0.1 2.7 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EON98790.1 - 0.0051 16.9 0.3 1.9 8.5 0.1 2.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 EON98790.1 - 0.015 14.9 0.2 0.027 14.1 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EON98790.1 - 0.018 15.1 0.6 0.12 12.4 0.6 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EON98790.1 - 0.035 13.8 0.0 0.09 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EON98790.1 - 0.058 13.9 0.0 0.22 12.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 EON98790.1 - 0.063 13.4 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 EON98790.1 - 0.13 12.2 0.3 1.4 8.8 0.1 2.3 1 1 0 2 2 2 0 AAA domain T5orf172 PF10544.9 EON98791.1 - 1.3e-15 57.8 1.2 2.5e-15 56.8 1.2 1.5 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EON98791.1 - 5.8e-06 26.9 1.7 1.2e-05 25.9 1.7 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 FAM221 PF14753.6 EON98791.1 - 0.0084 15.7 0.2 0.013 15.0 0.2 1.2 1 0 0 1 1 1 1 Protein FAM221A/B HET PF06985.11 EON98792.1 - 1.8e-28 99.7 9.5 1.8e-28 99.7 9.5 2.2 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) DUF3433 PF11915.8 EON98793.1 - 2.2e-28 98.5 12.7 5.9e-28 97.2 2.6 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Wbp11 PF09429.10 EON98794.1 - 5.7e-24 84.3 10.3 5.7e-24 84.3 10.3 1.8 2 0 0 2 2 2 1 WW domain binding protein 11 Lipoprotein_7 PF01540.16 EON98794.1 - 0.02 14.2 2.3 0.028 13.7 2.3 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein MFS_1 PF07690.16 EON98795.1 - 2.3e-22 79.4 54.6 2.2e-15 56.4 26.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2304 PF10066.9 EON98795.1 - 0.6 10.4 5.5 0.26 11.5 0.2 2.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF4663 PF15668.5 EON98796.1 - 0.016 14.3 1.4 0.019 14.1 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) RNA_polI_A34 PF08208.11 EON98796.1 - 0.064 13.3 16.4 0.092 12.8 16.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 AAA_11 PF13086.6 EON98796.1 - 0.13 12.1 7.8 0.14 11.9 7.8 1.1 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.9 EON98796.1 - 0.23 11.1 24.3 0.33 10.5 24.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.12 EON98796.1 - 0.32 10.8 12.3 0.34 10.7 12.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 EON98796.1 - 1.1 9.3 2.5 1.1 9.3 2.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SRP-alpha_N PF04086.13 EON98796.1 - 1.2 9.1 21.3 2.1 8.2 21.3 1.3 1 1 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Hid1 PF12722.7 EON98796.1 - 1.7 6.7 7.6 1.7 6.7 7.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2992 PF11208.8 EON98796.1 - 4.9 7.4 23.2 7.8 6.8 23.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) SET PF00856.28 EON98797.1 - 4.4e-07 30.4 0.1 0.0016 18.8 0.0 2.8 2 1 1 3 3 3 2 SET domain IMP2_C PF18591.1 EON98797.1 - 0.038 13.8 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Immune Mapped Protein 2 (IMP2) C-terminal domain Asp PF00026.23 EON98798.1 - 2.9e-63 214.2 3.1 4.1e-63 213.7 3.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EON98798.1 - 5.6e-09 36.5 3.4 2.7e-07 31.0 3.4 2.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EON98798.1 - 0.16 12.6 0.7 34 5.2 0.0 3.3 3 0 0 3 3 3 0 Aspartyl protease Yae1_N PF09811.9 EON98799.1 - 7e-15 54.5 1.4 1.2e-14 53.7 1.4 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Amidase PF01425.21 EON98801.1 - 2.8e-70 237.5 0.0 8.2e-70 236.0 0.0 1.7 1 1 0 1 1 1 1 Amidase Iso_dh PF00180.20 EON98802.1 - 2.4e-97 326.2 0.0 3.4e-97 325.7 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IF4E PF01652.18 EON98803.1 - 5.6e-54 182.2 0.0 6.9e-54 181.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E NGP1NT PF08153.12 EON98804.1 - 5.7e-49 165.6 0.9 5.7e-49 165.6 0.9 1.8 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EON98804.1 - 1.2e-17 64.1 0.1 4.9e-14 52.4 0.0 2.8 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EON98804.1 - 7.4e-06 25.6 0.0 2.2e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EON98804.1 - 4.4e-05 23.6 0.3 0.066 13.3 0.1 3.7 2 1 1 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 EON98804.1 - 0.00011 22.2 0.0 0.00055 19.9 0.0 2.1 2 1 0 2 2 2 1 RsgA GTPase Arf PF00025.21 EON98804.1 - 0.015 14.7 0.1 0.26 10.7 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.27 EON98804.1 - 0.064 12.8 0.1 3.2 7.2 0.0 2.9 1 1 0 3 3 3 0 Elongation factor Tu GTP binding domain FMN_red PF03358.15 EON98805.1 - 1.4e-09 37.8 0.0 1.9e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 EON98805.1 - 0.00018 21.7 0.0 0.0064 16.7 0.0 2.3 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 EON98805.1 - 0.00019 21.2 0.0 0.00022 21.0 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 EON98805.1 - 0.012 15.8 0.0 0.48 10.6 0.0 2.1 1 1 1 2 2 2 0 Flavodoxin domain ADH_zinc_N PF00107.26 EON98806.1 - 8.5e-32 109.9 0.7 1.4e-31 109.2 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON98806.1 - 2.4e-14 54.5 0.0 4.2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON98806.1 - 3.5e-05 23.6 0.0 0.00012 21.9 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 EON98806.1 - 0.029 14.6 0.1 0.056 13.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain ADH_N_2 PF16884.5 EON98806.1 - 0.031 14.2 0.0 0.096 12.6 0.0 1.8 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase AlaDh_PNT_C PF01262.21 EON98806.1 - 0.058 12.7 5.2 0.057 12.7 3.9 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_22 PF13383.6 EON98807.1 - 2.8e-18 66.4 0.0 3.8e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 EON98807.1 - 5.1e-05 23.4 0.0 6.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain BTRD1 PF17660.1 EON98807.1 - 0.0011 18.7 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 Bacterial tandem repeat domain 1 Ribosomal_S8 PF00410.19 EON98808.1 - 1.9e-13 50.4 0.0 6.9e-13 48.7 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S8 CR6_interact PF10147.9 EON98809.1 - 0.052 13.3 7.9 0.014 15.1 4.6 1.8 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF2207 PF09972.9 EON98809.1 - 0.072 11.9 1.0 0.097 11.4 0.0 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Protocadherin PF08374.11 EON98809.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.1 2 1 0 2 2 2 0 Protocadherin T2SSF PF00482.23 EON98809.1 - 0.48 10.4 0.0 0.48 10.4 0.0 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F SSP160 PF06933.11 EON98809.1 - 5.8 5.0 8.6 11 4.1 8.6 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 COXG PF06240.13 EON98810.1 - 0.094 12.5 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) Profilin PF00235.19 EON98811.1 - 2.3e-15 57.0 0.0 2.6e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Profilin GTP_EFTU PF00009.27 EON98812.1 - 7.4e-58 195.3 0.1 1.3e-57 194.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EON98812.1 - 1.7e-33 115.0 0.0 3.4e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EON98812.1 - 3.9e-32 110.2 0.0 7.7e-32 109.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EON98812.1 - 9.9e-21 73.6 0.0 2.2e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EON98812.1 - 2.7e-14 53.3 0.0 5.7e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EON98812.1 - 1.6e-06 28.0 0.0 4.9e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EON98812.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3933 PF13069.6 EON98812.1 - 0.081 12.8 0.1 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) Bac_luciferase PF00296.20 EON98813.1 - 1.2e-49 169.4 0.0 1.6e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase AMP-binding PF00501.28 EON98815.1 - 4.3e-20 71.7 0.1 5.2e-20 71.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON98815.1 - 4.1e-12 46.9 0.1 6.5e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sulfotransfer_4 PF17784.1 EON98816.1 - 9.2e-59 198.9 0.0 1.1e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EON98816.1 - 2.4e-05 24.8 0.0 0.00011 22.7 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase family ADH_N PF08240.12 EON98817.1 - 7e-11 42.0 0.0 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON98817.1 - 4.9e-10 39.5 0.5 9.2e-10 38.6 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EON98817.1 - 0.074 13.0 0.0 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase Peripla_BP_5 PF13433.6 EON98817.1 - 0.097 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain DUF726 PF05277.12 EON98818.1 - 3.3e-121 404.4 0.4 4.5e-121 404.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 EON98818.1 - 7.1e-05 23.0 0.0 0.00017 21.8 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.11 EON98818.1 - 0.0098 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain His_Phos_1 PF00300.22 EON98820.1 - 1.6e-09 37.8 0.0 8.3e-09 35.4 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Med1 PF10744.9 EON98822.1 - 3.9e-119 398.4 0.0 4.7e-119 398.1 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 BSD PF03909.17 EON98823.1 - 0.02 14.9 0.2 0.052 13.6 0.1 1.7 2 0 0 2 2 2 0 BSD domain Urotensin_II PF02083.15 EON98823.1 - 0.97 9.2 4.9 0.33 10.7 1.4 1.9 2 0 0 2 2 2 0 Urotensin II Coatomer_WDAD PF04053.14 EON98825.1 - 7.6e-172 572.3 0.0 1.3e-171 571.6 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 EON98825.1 - 5.5e-25 87.1 10.1 2.5e-06 28.1 0.1 8.5 8 1 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON98825.1 - 1.4e-05 25.2 0.0 3.4 8.0 0.0 5.3 4 2 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EON98825.1 - 0.021 14.9 0.0 12 6.0 0.0 3.9 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 EON98825.1 - 0.044 12.4 2.1 9.4 4.7 0.1 3.4 2 2 0 3 3 3 0 Nucleoporin Nup120/160 HD_3 PF13023.6 EON98826.1 - 3.8e-50 170.0 0.0 4.9e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EON98826.1 - 1e-10 41.7 0.1 2.9e-10 40.2 0.1 1.7 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EON98826.1 - 0.0035 17.5 0.0 0.0076 16.5 0.0 1.8 1 1 0 1 1 1 1 HD domain Polyoma_agno PF01736.16 EON98826.1 - 0.15 11.9 0.4 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 Polyomavirus agnoprotein EHN PF06441.12 EON98828.1 - 3.3e-38 130.4 0.6 9.6e-37 125.7 0.1 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EON98828.1 - 6.3e-13 49.0 0.0 1.2e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON98828.1 - 0.0011 19.7 7.8 0.0069 17.0 7.8 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Sugar_tr PF00083.24 EON98830.1 - 9.4e-93 311.5 21.8 1.2e-92 311.2 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON98830.1 - 3.6e-37 128.1 49.0 2.2e-31 109.1 23.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EON98830.1 - 0.088 11.2 7.8 1.5 7.2 0.1 2.4 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) SPT_ssu-like PF11779.8 EON98830.1 - 0.23 11.1 1.9 0.89 9.2 1.9 2.0 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like Glyoxalase PF00903.25 EON98831.1 - 6.2e-09 36.1 5.6 4.9e-07 30.0 1.9 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily eIF-3c_N PF05470.12 EON98831.1 - 0.31 9.3 0.0 0.4 8.9 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Thioredoxin PF00085.20 EON98832.1 - 1.1e-21 76.8 0.1 1.3e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EON98832.1 - 8.8e-08 32.4 0.0 1.3e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EON98832.1 - 2.4e-06 28.0 0.2 8.4e-06 26.2 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EON98832.1 - 0.0004 19.8 0.0 0.00042 19.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 EON98832.1 - 0.00063 19.5 0.0 0.00074 19.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EON98832.1 - 0.002 18.3 0.1 0.0029 17.7 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EON98832.1 - 0.0082 16.0 0.1 0.012 15.5 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.16 EON98832.1 - 0.023 13.6 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Phosducin Redoxin PF08534.10 EON98832.1 - 0.1 12.3 0.2 0.16 11.6 0.1 1.4 1 1 0 1 1 1 0 Redoxin DUF1304 PF06993.12 EON98834.1 - 3.5e-44 149.3 4.6 4.3e-44 149.0 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) SesA PF17107.5 EON98835.1 - 0.0047 17.1 0.0 0.0087 16.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases LMWPc PF01451.21 EON98835.1 - 0.0097 16.3 0.0 0.38 11.1 0.0 2.6 2 1 0 2 2 2 1 Low molecular weight phosphotyrosine protein phosphatase Rx_N PF18052.1 EON98835.1 - 0.063 13.5 1.9 0.19 12.0 1.9 1.8 1 0 0 1 1 1 0 Rx N-terminal domain RNA_pol_Rpb4 PF03874.16 EON98835.1 - 0.081 13.3 0.0 0.48 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb4 Inhibitor_G39P PF11417.8 EON98835.1 - 0.1 13.1 0.4 0.83 10.2 0.0 2.6 2 1 1 3 3 3 0 Loader and inhibitor of phage G40P adh_short PF00106.25 EON98836.1 - 4.7e-20 71.9 0.0 5.9e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON98836.1 - 1.9e-14 53.8 0.0 2.3e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON98836.1 - 0.033 14.1 0.1 0.064 13.2 0.1 1.5 1 1 0 1 1 1 0 KR domain TrkA_N PF02254.18 EON98836.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.21 EON98836.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Thioesterase PF00975.20 EON98837.1 - 6.9e-29 101.6 0.0 1.2e-28 100.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain AMP-binding PF00501.28 EON98837.1 - 1.1e-16 60.4 0.0 1.7e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EON98837.1 - 1.3e-10 41.5 1.4 3.4e-10 40.1 1.4 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 EON98837.1 - 0.0011 19.6 0.0 0.002 18.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON98837.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DLH PF01738.18 EON98838.1 - 2.9e-22 79.3 0.0 3.2e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EON98838.1 - 0.035 13.7 0.1 0.13 11.9 0.1 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold GATase PF00117.28 EON98839.1 - 2.7e-36 125.1 0.0 5.1e-36 124.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 EON98839.1 - 5.2e-34 116.2 0.0 1.1e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 EON98839.1 - 2.9e-06 26.6 0.0 0.001 18.2 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EON98839.1 - 7.9e-06 25.8 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 EON98839.1 - 0.23 10.2 0.0 0.47 9.2 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase Glyco_hydro_61 PF03443.14 EON98840.1 - 4.3e-60 203.2 0.2 5e-60 202.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Mannitol_dh_C PF08125.13 EON98841.1 - 7.6e-41 140.2 0.4 1.1e-40 139.7 0.4 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EON98841.1 - 4.4e-22 78.9 0.5 2.4e-21 76.5 0.1 2.3 2 1 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain Sacchrp_dh_NADP PF03435.18 EON98841.1 - 0.0024 18.1 0.3 1.7 8.9 0.1 2.6 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 EON98841.1 - 0.0042 16.7 1.1 0.0079 15.8 0.3 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Nitro_FeMo-Co PF02579.17 EON98841.1 - 0.095 13.0 0.6 9.9 6.6 0.1 3.2 2 1 1 3 3 3 0 Dinitrogenase iron-molybdenum cofactor TMEM192 PF14802.6 EON98842.1 - 0.079 12.0 2.3 0.11 11.5 2.3 1.2 1 0 0 1 1 1 0 TMEM192 family Herpes_gE PF02480.16 EON98842.1 - 0.093 11.5 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1180 PF06679.12 EON98842.1 - 0.14 12.6 0.2 0.18 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) GWT1 PF06423.12 EON98842.1 - 0.25 11.5 3.0 0.32 11.1 3.0 1.2 1 0 0 1 1 1 0 GWT1 DUF805 PF05656.14 EON98842.1 - 1.1 9.8 7.8 1.5 9.3 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Tetraspanin PF00335.20 EON98842.1 - 1.8 8.2 8.7 2.4 7.8 8.7 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF1700 PF08006.11 EON98842.1 - 2 7.9 15.1 0.18 11.3 10.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1700) DSPc PF00782.20 EON98843.1 - 1e-08 35.1 0.0 1.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EON98843.1 - 0.0075 16.3 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EON98843.1 - 0.021 14.4 0.4 0.063 12.8 0.2 1.9 2 1 0 2 2 2 0 Protein-tyrosine phosphatase CBM_6 PF03422.15 EON98844.1 - 2.6e-37 127.9 1.7 3e-37 127.7 1.7 1.0 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 EON98844.1 - 2.1e-09 37.5 0.4 2.5e-09 37.3 0.4 1.2 1 0 0 1 1 1 1 DUF5010 C-terminal domain p450 PF00067.22 EON98845.1 - 2.8e-32 112.1 0.0 2.8e-31 108.8 0.0 2.2 1 1 0 2 2 2 1 Cytochrome P450 Yqai PF09466.10 EON98845.1 - 0.057 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Hypothetical protein Yqai ADH_N PF08240.12 EON98846.1 - 1.2e-30 105.5 0.5 2.9e-30 104.3 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON98846.1 - 4.3e-14 52.6 0.3 3.2e-13 49.8 0.3 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EON98846.1 - 1.1e-06 28.3 1.4 6.3e-06 25.8 1.4 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EON98846.1 - 0.0004 19.7 0.5 0.00076 18.8 0.4 1.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 EON98846.1 - 0.00083 18.7 0.3 0.0048 16.2 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON98846.1 - 0.0012 19.4 0.9 0.021 15.4 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 EON98846.1 - 0.03 15.4 0.7 2.6 9.1 0.3 2.8 2 1 0 2 2 2 0 Zinc-binding dehydrogenase HI0933_like PF03486.14 EON98846.1 - 0.057 12.1 0.3 0.09 11.5 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 EON98846.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EON98846.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sugar_tr PF00083.24 EON98847.1 - 2.7e-107 359.4 31.5 3.4e-107 359.1 31.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON98847.1 - 3.4e-24 85.4 34.6 2.1e-22 79.5 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PetL PF05115.14 EON98847.1 - 6.7 6.8 8.9 0.37 10.8 2.4 2.5 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) Peptidase_C12 PF01088.21 EON98848.1 - 8.4e-53 179.2 0.0 9.4e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Pectate_lyase_3 PF12708.7 EON98849.1 - 1.8e-10 41.1 0.1 4e-06 26.8 0.0 2.9 2 1 1 3 3 3 2 Pectate lyase superfamily protein Acid_PPase PF12689.7 EON98850.1 - 5.7e-57 192.2 0.0 2e-56 190.5 0.0 1.8 1 1 0 1 1 1 1 Acid Phosphatase MFS_1 PF07690.16 EON98852.1 - 5.2e-15 55.2 17.1 5.8e-15 55.1 17.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EON98852.1 - 2.1e-05 24.3 1.9 4.2e-05 23.3 1.9 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DUF1485 PF07364.12 EON98853.1 - 4.7e-110 367.4 2.0 7.2e-110 366.8 2.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M81 MlrC_C PF07171.12 EON98853.1 - 1e-59 201.7 0.1 2e-59 200.7 0.1 1.5 1 0 0 1 1 1 1 MlrC C-terminus Glyco_hydro_61 PF03443.14 EON98853.1 - 2.6e-05 24.3 0.5 0.00014 21.9 0.1 2.3 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_19 PF03427.13 EON98853.1 - 0.00024 21.0 6.3 0.0012 18.8 6.3 2.3 1 0 0 1 1 1 1 Carbohydrate binding domain (family 19) TMF_TATA_bd PF12325.8 EON98854.1 - 0.00029 21.0 6.6 0.00029 21.0 6.6 7.9 1 1 7 8 8 7 2 TATA element modulatory factor 1 TATA binding BRE1 PF08647.11 EON98854.1 - 0.0003 20.8 8.8 0.0003 20.8 8.8 7.8 2 2 4 7 7 6 1 BRE1 E3 ubiquitin ligase DUF4201 PF13870.6 EON98854.1 - 0.00087 19.1 4.4 0.00087 19.1 4.4 6.7 1 1 3 6 6 6 2 Domain of unknown function (DUF4201) CALCOCO1 PF07888.11 EON98854.1 - 0.0015 17.5 43.4 0.0015 17.5 43.4 4.2 1 1 3 4 4 3 2 Calcium binding and coiled-coil domain (CALCOCO1) like bZIP_1 PF00170.21 EON98854.1 - 0.0028 17.7 4.1 0.0028 17.7 4.1 9.9 6 2 3 9 9 8 3 bZIP transcription factor Fez1 PF06818.15 EON98854.1 - 0.0061 17.0 10.3 0.0061 17.0 10.3 5.2 1 1 4 5 5 5 1 Fez1 JIP_LZII PF16471.5 EON98854.1 - 0.0085 16.2 7.1 0.0085 16.2 7.1 8.8 5 2 4 9 9 8 3 JNK-interacting protein leucine zipper II DUF3450 PF11932.8 EON98854.1 - 0.0088 15.4 13.0 0.0088 15.4 13.0 7.1 1 1 3 7 7 7 2 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 EON98854.1 - 0.0099 15.9 23.4 0.0099 15.9 23.4 5.5 1 1 5 6 6 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.13 EON98854.1 - 0.018 15.4 7.4 0.018 15.4 7.4 7.4 2 1 4 6 6 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region PRKG1_interact PF15898.5 EON98854.1 - 0.018 15.9 6.7 0.018 15.9 6.7 7.2 2 2 6 8 8 7 0 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 EON98854.1 - 0.028 14.9 3.3 0.028 14.9 3.3 10.1 2 2 7 10 10 9 0 Cell division protein ZapB Bap31_Bap29_C PF18035.1 EON98854.1 - 0.067 13.2 0.5 0.067 13.2 0.5 7.2 6 1 0 6 6 5 0 Bap31/Bap29 cytoplasmic coiled-coil domain Csm1_N PF18504.1 EON98854.1 - 0.11 12.9 0.3 0.11 12.9 0.3 9.3 5 3 4 10 10 8 0 Csm1 N-terminal domain ATG16 PF08614.11 EON98854.1 - 0.5 10.6 109.0 0.045 14.0 33.7 5.7 1 1 6 7 7 7 0 Autophagy protein 16 (ATG16) GAS PF13851.6 EON98854.1 - 1.2 8.4 97.7 0.75 9.1 10.4 6.3 1 1 6 7 7 7 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EON98854.1 - 4.3 6.1 100.9 0.093 11.6 25.2 4.4 1 1 3 4 4 4 0 Spc7 kinetochore protein Rhodanese PF00581.20 EON98855.1 - 9.5e-13 48.6 0.0 1.4e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Abhydrolase_6 PF12697.7 EON98856.1 - 1.1e-07 32.7 0.9 1.5e-07 32.3 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON98856.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold CRAL_TRIO PF00650.20 EON98857.1 - 1.9e-25 89.4 0.0 4.3e-25 88.3 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EON98857.1 - 2.5e-10 40.4 0.0 5.8e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain UPF0121 PF03661.13 EON98858.1 - 1e-20 74.2 7.4 1.2e-17 64.1 0.2 2.0 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0121) Amidohydro_2 PF04909.14 EON98859.1 - 1.3e-29 104.0 0.2 1.6e-29 103.6 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.16 EON98860.1 - 4.4e-15 55.5 59.5 3.3e-10 39.4 27.7 2.5 2 1 0 3 3 3 2 Major Facilitator Superfamily tRNA-synt_2 PF00152.20 EON98861.1 - 9.9e-56 189.1 0.0 1.3e-55 188.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Sugar_tr PF00083.24 EON98862.1 - 1.3e-66 225.3 30.2 1.5e-66 225.1 30.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON98862.1 - 1.1e-13 50.8 41.9 1.2e-13 50.7 35.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PIP5K PF01504.18 EON98863.1 - 2.9e-100 335.0 0.1 6.4e-100 333.9 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Sugar_tr PF00083.24 EON98864.1 - 2.2e-85 287.2 19.8 2.8e-85 286.9 19.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON98864.1 - 1.1e-26 93.6 22.1 1.1e-26 93.6 22.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EON98864.1 - 1.1e-07 30.7 1.9 1.9e-07 29.9 1.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2929 PF11151.8 EON98864.1 - 7.3 7.0 11.4 11 6.4 2.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) Glyco_hydro_28 PF00295.17 EON98865.1 - 3.6e-15 55.8 0.8 1.3e-11 44.2 0.3 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Sporozoite_P67 PF05642.11 EON98865.1 - 0.38 8.8 2.0 0.35 8.9 2.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Rod_cone_degen PF15201.6 EON98867.1 - 0.066 13.3 0.4 0.23 11.6 0.4 2.0 1 0 0 1 1 1 0 Progressive rod-cone degeneration Myb_DNA-binding PF00249.31 EON98868.1 - 2.1e-13 50.2 6.9 5.3e-06 26.5 3.3 3.4 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EON98868.1 - 8.3e-11 42.0 1.2 1.3e-06 28.6 0.5 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EON98868.1 - 2.6e-05 24.5 1.3 0.00017 21.9 1.3 2.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain PriCT_2 PF08707.11 EON98868.1 - 0.036 14.4 0.0 0.15 12.5 0.0 2.0 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) MADF_DNA_bdg PF10545.9 EON98868.1 - 0.079 13.3 0.1 0.079 13.3 0.1 2.7 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Spore_SspJ PF09575.10 EON98868.1 - 8.5 6.8 10.5 0.088 13.2 0.4 3.1 3 0 0 3 3 3 0 Small spore protein J (Spore_SspJ) Pkinase_fungal PF17667.1 EON98869.1 - 0.012 14.4 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 EON98869.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FAD_binding_3 PF01494.19 EON98870.1 - 3.2e-12 46.4 0.1 4.6e-10 39.3 0.0 2.8 1 1 1 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EON98870.1 - 0.0046 16.1 0.0 0.0085 15.2 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EON98870.1 - 0.033 13.8 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase SYS1 PF09801.9 EON98871.1 - 6.7e-50 169.0 5.6 7.7e-50 168.8 5.6 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network FUSC-like PF12805.7 EON98871.1 - 4.4 6.3 9.0 0.68 9.0 0.3 2.1 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS adh_short PF00106.25 EON98872.1 - 1.7e-17 63.6 0.0 4.4e-12 45.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON98872.1 - 1.1e-09 38.2 0.0 6.2e-07 29.2 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase COX6B PF02297.17 EON98873.1 - 9.6e-24 83.4 3.4 1.3e-23 83.0 3.4 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Tyrosinase PF00264.20 EON98874.1 - 2.3e-33 116.4 0.1 3.2e-33 115.9 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2263 PF10021.9 EON98875.1 - 7.9e-11 42.5 0.0 1.3e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) GMC_oxred_N PF00732.19 EON98876.1 - 6.6e-51 173.4 0.0 8.8e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EON98876.1 - 1.7e-38 132.4 0.0 2.7e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EON98876.1 - 9.8e-07 28.2 0.1 0.017 14.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EON98876.1 - 1e-05 25.3 0.3 0.00076 19.2 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EON98876.1 - 1.1e-05 25.6 0.1 0.00016 21.8 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EON98876.1 - 1.8e-05 24.0 0.0 2.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EON98876.1 - 0.00069 18.9 0.0 0.0029 16.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EON98876.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 EON98876.1 - 0.024 15.2 0.1 0.69 10.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EON98876.1 - 0.027 13.7 0.0 0.096 11.9 0.0 1.8 2 0 0 2 2 2 0 Thi4 family MAP PF03642.13 EON98876.1 - 0.22 11.9 0.0 4.4 7.7 0.0 2.3 2 0 0 2 2 2 0 MAP domain Linker_histone PF00538.19 EON98877.1 - 3.9e-29 100.8 0.3 1.1e-28 99.4 0.3 1.8 1 0 0 1 1 1 1 linker histone H1 and H5 family Type_III_YscG PF09477.10 EON98878.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Herpes_LMP1 PF05297.11 EON98878.1 - 4.6 6.3 5.2 6.6 5.8 5.2 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Peptidase_S8 PF00082.22 EON98880.1 - 0.0065 15.8 0.2 0.0079 15.5 0.2 1.1 1 0 0 1 1 1 1 Subtilase family Lactamase_B_6 PF16661.5 EON98881.1 - 3.4e-65 219.1 0.0 5.3e-65 218.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EON98881.1 - 9.7e-56 188.6 0.8 3.7e-55 186.7 0.0 2.2 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 EON98881.1 - 1.1e-15 57.3 0.0 2.5e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Beta-Casp PF10996.8 EON98881.1 - 2.7e-15 56.6 0.0 8.5e-15 55.0 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.7 EON98881.1 - 0.024 14.1 0.1 0.074 12.5 0.1 1.8 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EON98881.1 - 0.12 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily MFS_1 PF07690.16 EON98882.1 - 2.2e-40 138.7 25.5 2.5e-40 138.5 25.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EON98882.1 - 0.25 11.0 9.5 0.27 10.9 4.9 2.8 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 MTS_N PF08468.11 EON98883.1 - 0.14 12.2 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal MFS_1 PF07690.16 EON98884.1 - 4.1e-18 65.4 7.5 4e-16 58.9 7.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3328 PF11807.8 EON98885.1 - 9.1e-55 185.8 0.1 1.3e-54 185.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans_2 PF11951.8 EON98886.1 - 3.9e-21 75.3 0.4 5.2e-21 74.9 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EON98886.1 - 8.5e-09 35.4 11.8 1.3e-08 34.8 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 EON98886.1 - 0.049 13.5 4.7 0.14 12.1 4.7 1.9 1 0 0 1 1 1 0 AT hook motif O-FucT PF10250.9 EON98887.1 - 8.2e-10 38.9 0.0 6.7e-09 35.9 0.0 2.2 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase NmrA PF05368.13 EON98888.1 - 7.7e-33 114.0 0.0 9.3e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EON98888.1 - 5.4e-11 42.7 0.0 8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EON98888.1 - 6.8e-05 22.4 0.1 0.00028 20.4 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EON98888.1 - 0.0028 17.6 0.1 0.0045 16.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 EON98888.1 - 0.003 18.0 0.1 0.0057 17.1 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EON98888.1 - 0.037 14.1 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_25 PF13649.6 EON98890.1 - 6.1e-12 46.1 0.0 1.2e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON98890.1 - 9.3e-11 42.2 0.0 1.5e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON98890.1 - 1.2e-10 42.0 0.0 1.9e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON98890.1 - 1.7e-09 37.6 0.0 2.9e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON98890.1 - 3.1e-07 30.4 0.0 4.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON98890.1 - 7.2e-06 25.5 0.1 1.4e-05 24.5 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EON98890.1 - 0.0011 18.5 0.1 0.0027 17.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EON98890.1 - 0.067 12.5 0.3 0.13 11.5 0.3 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase CheR PF01739.18 EON98890.1 - 0.076 12.5 0.0 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain DnaB_bind PF10410.9 EON98890.1 - 0.078 13.2 0.0 1.9 8.8 0.0 2.6 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase Sec23_trunk PF04811.15 EON98891.1 - 1.8e-56 191.4 0.0 4.1e-56 190.3 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EON98891.1 - 2.9e-23 81.6 0.0 5.9e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EON98891.1 - 6e-18 65.4 0.0 1.1e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EON98891.1 - 5.6e-15 55.1 5.0 1.4e-14 53.8 5.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EON98891.1 - 6.7e-05 22.7 0.0 0.00019 21.3 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Aldedh PF00171.22 EON98892.1 - 9.1e-159 528.8 0.2 1.1e-158 528.6 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 EON98892.1 - 0.04 13.8 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 WTAP/Mum2p family AAA_16 PF13191.6 EON98893.1 - 3.6e-09 37.2 0.0 9.2e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EON98893.1 - 0.0016 18.4 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_29 PF13555.6 EON98893.1 - 0.0018 18.0 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EON98893.1 - 0.16 12.2 0.4 1 9.7 0.4 2.2 1 1 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 EON98894.1 - 9.3e-24 84.0 21.4 1.4e-23 83.4 21.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EON98894.1 - 2.5e-13 50.7 0.0 5e-13 49.8 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EON98894.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EON98894.1 - 0.027 14.7 0.1 0.14 12.4 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 EON98894.1 - 0.04 13.3 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 EON98894.1 - 0.071 12.2 28.6 0.41 9.7 1.4 2.4 3 0 0 3 3 3 0 ABC-2 family transporter protein Ribonuc_L-PSP PF01042.21 EON98897.1 - 2.7e-11 43.5 0.0 3.2e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP fn3_3 PF14686.6 EON98898.1 - 1.5e-24 85.5 0.1 4.2e-24 84.1 0.1 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 EON98898.1 - 3.9e-23 82.1 0.0 9e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III PDZ_1 PF12812.7 EON98899.1 - 1.3e-53 178.9 0.0 3.8e-34 116.6 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 EON98899.1 - 9.4e-25 88.3 1.0 1.8e-21 77.6 0.1 2.4 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 EON98899.1 - 1.8e-15 56.5 0.1 1.8e-05 24.5 0.2 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 EON98899.1 - 1.3e-14 54.2 0.6 3.2e-06 27.4 0.1 4.6 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 EON98899.1 - 3.3e-09 37.0 0.0 0.00053 20.3 0.0 4.2 4 0 0 4 4 4 2 PDZ domain Trypsin PF00089.26 EON98899.1 - 0.00033 20.6 0.0 0.00099 19.0 0.0 1.7 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 EON98899.1 - 0.0016 18.3 1.2 0.15 12.0 0.4 3.4 4 0 0 4 4 4 1 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 EON98899.1 - 0.027 14.2 0.0 0.24 11.1 0.1 2.5 2 0 0 2 2 2 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Peptidase_S46 PF10459.9 EON98899.1 - 0.23 10.0 0.2 0.42 9.2 0.2 1.3 1 0 0 1 1 1 0 Peptidase S46 DUF31 PF01732.16 EON98899.1 - 0.29 10.6 0.6 0.46 10.0 0.6 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Lactonase PF10282.9 EON98900.1 - 5.7e-65 219.8 1.5 8.1e-54 183.2 0.1 3.0 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller TGT PF01702.18 EON98901.1 - 1.7e-130 435.3 0.0 1.9e-130 435.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Sulf_transp PF04143.14 EON98902.1 - 5.7e-28 98.4 33.8 1.3e-27 97.2 33.8 1.6 1 1 0 1 1 1 1 Sulphur transport GATA PF00320.27 EON98903.1 - 8.5e-15 54.1 2.5 1.7e-14 53.1 2.5 1.5 1 0 0 1 1 1 1 GATA zinc finger ATG16 PF08614.11 EON98903.1 - 0.00075 19.8 6.0 0.00075 19.8 6.0 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) FPP PF05911.11 EON98903.1 - 0.0021 16.4 3.4 0.0031 15.8 2.7 1.6 2 0 0 2 2 2 1 Filament-like plant protein, long coiled-coil Atg14 PF10186.9 EON98903.1 - 0.0058 15.7 4.7 0.011 14.9 4.7 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4226 PF10774.9 EON98903.1 - 0.029 14.7 1.9 0.029 14.7 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) ArfGap PF01412.18 EON98903.1 - 0.052 13.6 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.12 EON98903.1 - 0.057 12.9 0.5 0.11 12.0 0.5 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding CENP-F_leu_zip PF10473.9 EON98903.1 - 0.075 13.1 10.7 8.1 6.5 0.0 2.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 JIP_LZII PF16471.5 EON98903.1 - 0.13 12.4 9.3 1.7 8.9 6.6 2.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II LMBR1 PF04791.16 EON98903.1 - 0.18 10.7 0.1 0.18 10.7 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 EON98903.1 - 0.18 10.4 2.2 0.26 9.9 2.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Macoilin PF09726.9 EON98903.1 - 0.57 8.7 6.3 0.79 8.2 6.3 1.3 1 1 0 1 1 1 0 Macoilin family eIF-5_eIF-2B PF01873.17 EON98903.1 - 0.57 10.1 2.2 0.61 10.0 0.5 1.9 2 0 0 2 2 2 0 Domain found in IF2B/IF5 TMPIT PF07851.13 EON98903.1 - 1.8 7.7 3.1 2.9 7.1 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein IFP_35_N PF07334.13 EON98903.1 - 2.1 8.5 5.5 1.1 9.4 1.4 2.6 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF2630 PF10944.8 EON98903.1 - 3.3 8.2 8.9 1.9 9.0 6.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2630) Spc24 PF08286.11 EON98903.1 - 9 6.6 7.4 7.4 6.9 5.3 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Hist_deacetyl PF00850.19 EON98904.1 - 1.1e-46 159.7 0.3 1.5e-46 159.3 0.3 1.1 1 0 0 1 1 1 1 Histone deacetylase domain SRP54 PF00448.22 EON98905.1 - 8.4e-07 28.8 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 EON98905.1 - 0.00019 22.0 0.0 0.00044 20.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EON98905.1 - 0.00044 20.7 0.0 0.00078 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EON98905.1 - 0.00047 19.5 0.0 0.00075 18.8 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin KAP_NTPase PF07693.14 EON98905.1 - 0.00052 19.3 0.0 0.00081 18.7 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain NACHT PF05729.12 EON98905.1 - 0.00092 19.2 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain MeaB PF03308.16 EON98905.1 - 0.0013 17.8 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 EON98905.1 - 0.003 17.3 0.0 0.091 12.5 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.6 EON98905.1 - 0.0034 17.4 0.0 0.007 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EON98905.1 - 0.0039 17.6 0.0 0.0069 16.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EON98905.1 - 0.012 15.9 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EON98905.1 - 0.017 15.0 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 NTPase cobW PF02492.19 EON98905.1 - 0.018 14.6 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EON98905.1 - 0.019 15.1 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EON98905.1 - 0.02 14.9 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.19 EON98905.1 - 0.02 14.7 0.0 0.73 9.6 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase ArsA_ATPase PF02374.15 EON98905.1 - 0.047 12.9 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase ATP_bind_1 PF03029.17 EON98905.1 - 0.049 13.4 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 EON98905.1 - 0.066 13.5 0.0 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_31 PF13614.6 EON98905.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EON98905.1 - 0.079 13.5 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.17 EON98905.1 - 0.082 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Thymidylate kinase NB-ARC PF00931.22 EON98905.1 - 0.094 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF3747 PF12565.8 EON98905.1 - 0.096 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) AAA_5 PF07728.14 EON98905.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EON98905.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 EON98905.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 EON98905.1 - 0.13 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 EON98905.1 - 0.15 12.5 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 EON98905.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 EON98905.1 - 0.18 12.2 0.0 4.8 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain ACC_epsilon PF13822.6 EON98905.1 - 0.19 12.4 4.2 0.28 11.9 0.0 2.6 3 0 0 3 3 2 0 Acyl-CoA carboxylase epsilon subunit Mit_KHE1 PF10173.9 EON98906.1 - 4.3e-63 212.9 0.2 4.3e-63 212.9 0.2 1.7 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related Hexokinase_2 PF03727.16 EON98907.1 - 2.3e-48 164.7 0.0 3.2e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EON98907.1 - 4.8e-46 157.2 0.0 6.8e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FmdA_AmdA PF03069.15 EON98908.1 - 2.3e-44 151.8 0.0 2.5e-26 92.4 0.0 2.1 1 1 1 2 2 2 2 Acetamidase/Formamidase family Cofilin_ADF PF00241.20 EON98909.1 - 1.3e-15 57.3 0.0 2.2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RIO1 PF01163.22 EON98910.1 - 1.9e-41 141.8 0.1 1.7e-28 99.5 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 EON98910.1 - 4.6e-32 110.1 0.0 1.2e-31 108.7 0.0 1.7 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 EON98910.1 - 9.4e-07 29.0 0.0 0.0083 16.1 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EON98910.1 - 2.7e-06 26.9 0.0 0.00025 20.4 0.0 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_Rpc4 PF05132.14 EON98910.1 - 0.025 15.0 1.0 0.025 15.0 1.0 1.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 RXT2_N PF08595.11 EON98910.1 - 2 8.4 5.9 3.4 7.7 5.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.6 EON98910.1 - 2.8 8.4 7.4 5.8 7.3 7.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 EON98910.1 - 8.6 5.6 7.5 12 5.1 7.5 1.2 1 0 0 1 1 1 0 NOA36 protein PP2C PF00481.21 EON98912.1 - 1.2e-28 100.5 0.0 1.9e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EON98912.1 - 0.12 12.3 0.8 4.3 7.2 0.0 2.6 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) RPN1_RPN2_N PF17781.1 EON98913.1 - 2.1e-113 378.8 2.6 3.7e-113 378.0 2.6 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EON98913.1 - 5.8e-30 103.1 0.0 1e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EON98913.1 - 2.2e-21 75.1 15.9 0.00011 22.4 0.1 9.0 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EON98913.1 - 1.1e-07 32.2 0.6 0.0022 18.4 0.0 4.1 4 1 1 5 5 5 3 HEAT repeats Pinin_SDK_memA PF04696.13 EON98913.1 - 0.42 10.7 3.7 0.88 9.6 3.7 1.5 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region ADH_zinc_N PF00107.26 EON98914.1 - 2.1e-20 73.0 0.1 3.1e-20 72.5 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON98914.1 - 1.4e-09 39.1 0.0 3.1e-09 38.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON98914.1 - 1.6e-05 24.8 0.0 2.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EON98914.1 - 0.017 14.6 0.1 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.13 EON98915.1 - 7.2e-36 123.9 0.0 1.1e-35 123.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EON98915.1 - 5.7e-09 36.1 0.0 8.2e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EON98915.1 - 0.00064 18.8 0.0 0.00091 18.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EON98915.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family G-alpha PF00503.20 EON98916.1 - 8.6e-117 390.2 1.9 9.9e-117 390.0 1.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EON98916.1 - 1.6e-15 57.0 0.5 3.3e-10 39.7 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EON98916.1 - 0.0017 17.7 4.8 0.077 12.3 0.2 2.8 2 2 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EON98916.1 - 0.0034 17.6 0.5 1.3 9.3 0.1 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EON98916.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DIM1 PF02966.16 EON98917.1 - 4.1e-70 233.7 0.2 4.7e-70 233.5 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.6 EON98917.1 - 0.096 13.0 0.3 0.18 12.2 0.3 1.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin PF00085.20 EON98917.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Ras PF00071.22 EON98918.1 - 7.6e-60 201.2 0.2 8.9e-60 201.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EON98918.1 - 1.9e-20 73.3 0.0 2.9e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EON98918.1 - 4.2e-08 32.8 0.0 4.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EON98918.1 - 8.5e-06 25.4 0.1 4.4e-05 23.1 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EON98918.1 - 3.7e-05 23.7 0.5 0.12 12.3 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EON98918.1 - 0.0015 18.6 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EON98918.1 - 0.0019 18.2 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 EON98918.1 - 0.0048 16.4 0.0 0.0094 15.5 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 EON98918.1 - 0.06 13.1 1.7 0.67 9.7 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 EON98918.1 - 0.095 12.7 0.3 4.5 7.3 0.1 2.7 1 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EON98918.1 - 0.2 11.4 0.9 2.6 7.7 0.2 2.3 1 1 1 2 2 2 0 IstB-like ATP binding protein VGCC_beta4Aa_N PF12052.8 EON98918.1 - 1.8 8.7 3.7 0.97 9.6 0.8 2.0 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal IBR PF01485.21 EON98919.1 - 8e-06 26.0 4.5 8e-06 26.0 4.5 5.2 4 1 0 4 4 4 1 IBR domain, a half RING-finger domain Ribosomal_L20 PF00453.18 EON98919.1 - 1.3 9.2 3.8 0.47 10.6 0.7 1.9 2 0 0 2 2 2 0 Ribosomal protein L20 Fungal_trans PF04082.18 EON98920.1 - 6.2e-20 71.3 0.0 9.7e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 EON98920.1 - 0.11 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF4306 PF14154.6 EON98920.1 - 0.13 12.5 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) RPA_C PF08784.11 EON98921.1 - 3e-23 82.4 0.4 3e-23 82.4 0.4 1.7 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EON98921.1 - 4.3e-10 39.4 0.2 1.1e-09 38.2 0.1 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 EON98921.1 - 8.5e-05 22.4 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 HTH_Tnp_Tc5 PF03221.16 EON98922.1 - 2.5e-07 30.6 0.0 0.00099 19.1 0.0 3.4 3 0 0 3 3 3 2 Tc5 transposase DNA-binding domain RsgA_N PF16745.5 EON98922.1 - 0.064 13.0 0.0 12 5.7 0.0 2.4 2 0 0 2 2 2 0 RsgA N-terminal domain PHP PF02811.19 EON98923.1 - 9.9e-13 48.7 0.0 1.5e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 PHP domain Npa1 PF11707.8 EON98924.1 - 1.9e-98 330.0 0.0 4.1e-98 328.9 0.0 1.6 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EON98924.1 - 1.4e-60 204.4 0.0 8.6e-59 198.5 0.0 2.7 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 REV1_C PF16727.5 EON98924.1 - 0.043 14.2 0.1 1.5 9.2 0.0 3.0 1 1 1 2 2 2 0 DNA repair protein REV1 C-terminal domain DUF3384 PF11864.8 EON98924.1 - 2.5 6.9 5.7 0.74 8.6 0.1 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3384) ParA PF10609.9 EON98925.1 - 4.4e-95 317.8 0.0 5.1e-95 317.6 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EON98925.1 - 5.1e-07 29.8 0.0 1.8e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EON98925.1 - 0.00016 21.0 0.5 0.0013 18.0 0.1 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 EON98925.1 - 0.00049 20.1 0.0 0.0029 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EON98925.1 - 0.0016 18.1 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 EON98925.1 - 0.011 15.5 0.0 0.48 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EON98925.1 - 0.018 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 EON98925.1 - 0.049 13.3 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 EON98925.1 - 0.05 13.0 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 EON98925.1 - 0.068 12.4 0.0 0.17 11.1 0.0 1.6 1 1 0 1 1 1 0 ATPase MipZ TsaE PF02367.17 EON98925.1 - 0.075 13.0 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EON98925.1 - 0.084 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase CLP1_P PF16575.5 EON98925.1 - 0.12 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Sec1 PF00995.23 EON98926.1 - 1.4e-23 84.0 0.3 1.7e-23 83.7 0.3 1.0 1 0 0 1 1 1 1 Sec1 family HTH_micro PF17007.5 EON98926.1 - 0.0048 15.8 0.1 0.0062 15.4 0.1 1.1 1 0 0 1 1 1 1 HTH-like Phosphorylase PF00343.20 EON98927.1 - 0 1055.6 0.0 0 1055.4 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase TFCD_C PF12612.8 EON98928.1 - 2.8e-23 82.8 0.0 3.4e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal Ysc84 PF04366.12 EON98929.1 - 1.1e-34 119.0 0.0 1.9e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator DNA_pol_phi PF04931.13 EON98929.1 - 0.67 8.0 9.0 1.3 7.0 9.0 1.4 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 EON98929.1 - 0.91 8.8 17.0 1.7 7.9 17.0 1.4 1 0 0 1 1 1 0 BUD22 MoCF_biosynth PF00994.24 EON98930.1 - 3.1e-29 101.5 0.0 4.9e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain DcpS PF05652.12 EON98932.1 - 6.5e-38 129.8 0.0 1.1e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 EON98932.1 - 1.5e-33 115.7 0.2 2.3e-33 115.1 0.2 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF1938 PF09153.10 EON98932.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) His_Phos_2 PF00328.22 EON98933.1 - 5.1e-114 381.6 0.4 8.9e-114 380.8 0.4 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EON98933.1 - 2.3e-08 34.1 0.0 5.4e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EON98933.1 - 5.3e-07 29.4 0.0 9.7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DUF4718 PF15842.5 EON98933.1 - 0.066 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Avl9 PF09794.9 EON98935.1 - 5.7e-89 298.5 0.1 9.8e-54 182.5 0.0 3.1 1 1 2 3 3 3 3 Transport protein Avl9 SPA PF08616.10 EON98935.1 - 6.6e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Pou PF00157.17 EON98936.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain ECM11 PF15463.6 EON98937.1 - 1.1e-45 155.5 0.9 1.1e-45 155.5 0.9 1.6 2 0 0 2 2 2 1 Extracellular mutant protein 11 LIP PF03583.14 EON98938.1 - 2.3e-62 210.9 0.1 2.9e-62 210.6 0.1 1.0 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 EON98938.1 - 0.12 11.8 0.2 0.5 9.8 0.1 2.0 2 1 1 3 3 3 0 Prolyl oligopeptidase family Acetyltransf_9 PF13527.7 EON98940.1 - 6.6e-07 29.5 0.0 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EON98940.1 - 7.2e-07 29.5 0.1 1.3e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EON98940.1 - 7.5e-07 29.1 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON98940.1 - 2.9e-06 27.5 0.1 4.6e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EON98940.1 - 9.3e-05 22.5 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DnaB_bind PF10410.9 EON98940.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase FR47 PF08445.10 EON98940.1 - 0.098 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DUF676 PF05057.14 EON98941.1 - 7.4e-06 25.6 0.1 1.3e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NARP1 PF12569.8 EON98941.1 - 0.25 10.2 1.3 0.32 9.8 1.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BRO1 PF03097.18 EON98942.1 - 4.4e-135 450.4 1.5 4.4e-135 450.4 1.5 1.9 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EON98942.1 - 2e-81 273.5 18.2 2e-81 273.5 18.2 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Gp58 PF07902.11 EON98942.1 - 0.006 14.9 5.9 0.012 14.0 5.9 1.4 1 0 0 1 1 1 1 gp58-like protein FlaC_arch PF05377.11 EON98942.1 - 0.042 14.2 3.8 1.1 9.6 0.0 3.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Phage_tail_APC PF16778.5 EON98942.1 - 0.07 13.0 0.2 0.92 9.4 0.1 2.8 2 0 0 2 2 2 0 Phage tail assembly chaperone protein COG2 PF06148.11 EON98942.1 - 0.43 10.7 8.0 0.24 11.5 0.7 3.6 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF416 PF04222.12 EON98942.1 - 0.53 9.7 7.1 0.74 9.2 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF416) Cep57_CLD_2 PF14197.6 EON98942.1 - 6.2 7.0 14.7 26 5.0 0.1 4.8 4 1 0 4 4 4 0 Centrosome localisation domain of PPC89 Lon_C PF05362.13 EON98943.1 - 2.3e-67 226.5 0.3 5.3e-67 225.3 0.3 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EON98943.1 - 6.8e-31 107.8 0.0 1.8e-30 106.4 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EON98943.1 - 3.2e-23 82.6 0.0 8.4e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EON98943.1 - 4e-09 36.6 0.0 1.1e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EON98943.1 - 5.5e-08 32.7 0.0 1.1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 EON98943.1 - 1.4e-05 25.6 2.5 1.6e-05 25.4 0.1 2.3 2 1 0 2 2 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EON98943.1 - 3.2e-05 23.7 0.0 0.00011 22.0 0.0 1.9 2 0 0 2 2 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 EON98943.1 - 0.00011 22.0 0.0 0.0004 20.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EON98943.1 - 0.00011 22.0 0.0 0.00028 20.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EON98943.1 - 0.00019 21.7 0.0 0.0062 16.8 0.0 2.9 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.14 EON98943.1 - 0.0012 19.0 0.0 0.005 17.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EON98943.1 - 0.0041 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EON98943.1 - 0.0073 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain NACHT PF05729.12 EON98943.1 - 0.024 14.6 0.0 0.096 12.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 EON98943.1 - 0.032 14.6 0.0 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 EON98943.1 - 0.034 13.7 0.1 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EON98943.1 - 0.037 13.4 0.0 0.098 12.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein AAA_18 PF13238.6 EON98943.1 - 0.041 14.4 0.0 0.12 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EON98943.1 - 0.061 13.3 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EON98943.1 - 0.072 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EON98943.1 - 0.072 12.5 0.1 0.17 11.2 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EON98943.1 - 0.091 13.1 0.1 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EON98943.1 - 0.098 12.6 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase CENP-X PF09415.10 EON98943.1 - 0.11 12.9 0.0 0.42 11.0 0.0 2.0 1 0 0 1 1 1 0 CENP-S associating Centromere protein X AAA_7 PF12775.7 EON98943.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region YlqD PF11068.8 EON98943.1 - 0.2 12.0 6.6 0.67 10.3 6.6 1.8 1 0 0 1 1 1 0 YlqD protein AAA_23 PF13476.6 EON98943.1 - 0.27 11.7 0.0 0.27 11.7 0.0 3.4 2 1 1 3 3 1 0 AAA domain AAA_11 PF13086.6 EON98943.1 - 2.5 7.8 8.0 1.3 8.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain MFS_1 PF07690.16 EON98944.1 - 5.5e-06 25.6 38.2 5.8e-05 22.2 34.2 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cullin PF00888.22 EON98945.1 - 1.4e-199 664.7 12.4 2.1e-199 664.2 12.4 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EON98945.1 - 2.7e-26 91.4 5.7 1.1e-25 89.5 5.7 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 EON98945.1 - 0.065 13.8 2.7 0.17 12.5 0.8 2.8 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF1803 PF08820.10 EON98945.1 - 0.15 12.1 5.3 4.3 7.4 0.1 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1803) FAD_SOX PF18371.1 EON98945.1 - 0.15 12.4 1.0 1.2 9.5 0.1 3.1 3 0 0 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase FAM194 PF14977.6 EON98945.1 - 0.42 9.9 3.9 0.39 10.0 0.9 2.5 2 0 0 2 2 2 0 FAM194 protein Glyco_hydro_76 PF03663.14 EON98946.1 - 7.5e-48 163.9 6.0 9.5e-48 163.5 6.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EON98946.1 - 5.4e-05 22.4 0.2 0.032 13.3 0.0 2.7 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 GILT PF03227.16 EON98947.1 - 1.6e-19 70.1 0.1 2.3e-19 69.6 0.1 1.2 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) FAD_binding_4 PF01565.23 EON98948.1 - 1.2e-24 86.6 0.7 1.9e-24 86.0 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Actin PF00022.19 EON98949.1 - 2.2e-13 49.6 0.0 3.8e-12 45.5 0.0 2.3 2 0 0 2 2 2 2 Actin Sugar_tr PF00083.24 EON98950.1 - 1.9e-25 89.7 0.0 2.1e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Claudin_3 PF06653.11 EON98950.1 - 0.077 12.9 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Utp21 PF04192.12 EON98951.1 - 5.4e-85 284.6 0.0 7.3e-85 284.2 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 EON98951.1 - 6.1e-17 61.7 21.4 9.5e-05 23.1 0.4 9.3 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON98951.1 - 6.3e-14 52.0 0.0 0.018 15.3 0.0 6.2 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EON98951.1 - 1.6e-06 27.0 0.2 1 8.0 0.0 3.6 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EON98951.1 - 0.00016 20.4 0.0 0.00032 19.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 EON98951.1 - 0.0011 17.9 0.0 0.017 13.9 0.0 2.2 1 1 1 2 2 2 1 Nup133 N terminal like WD40_like PF17005.5 EON98951.1 - 0.18 11.1 0.6 0.54 9.5 0.2 1.8 1 1 1 2 2 2 0 WD40-like domain VID27 PF08553.10 EON98951.1 - 0.25 10.4 0.0 0.47 9.4 0.0 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain adh_short PF00106.25 EON98952.1 - 6.1e-84 280.3 11.9 1.9e-43 148.2 1.3 2.6 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON98952.1 - 2.8e-64 216.9 11.0 6.1e-35 120.9 0.8 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EON98952.1 - 4.4e-32 110.2 0.0 1.1e-31 108.9 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 EON98952.1 - 3e-30 105.5 4.5 2.3e-14 53.7 0.2 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 EON98952.1 - 0.0014 18.2 4.4 0.04 13.4 0.1 2.7 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EON98952.1 - 0.0022 17.3 0.7 0.097 12.0 0.5 2.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAM25 PF15825.5 EON98952.1 - 0.21 12.0 8.5 2.4 8.6 0.8 2.9 2 0 0 2 2 2 0 FAM25 family PglL_A PF15864.5 EON98952.1 - 2.7 7.8 8.0 10 6.0 1.0 2.4 2 0 0 2 2 2 0 Protein glycosylation ligase NUDIX PF00293.28 EON98953.1 - 3.9e-26 91.6 0.0 6e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain RRM_1 PF00076.22 EON98954.1 - 2.9e-23 81.5 0.0 9e-11 41.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_4 PF13894.6 EON98955.1 - 5.2e-11 42.4 19.4 0.012 16.4 0.1 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 EON98955.1 - 7.9e-10 38.8 12.2 0.00012 22.3 0.8 3.9 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EON98955.1 - 8.4e-09 35.5 10.5 0.00087 19.5 1.3 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EON98955.1 - 1e-08 35.1 24.9 0.012 16.0 0.9 5.2 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EON98955.1 - 3.8e-06 27.1 14.3 0.11 13.0 0.1 4.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_2 PF12756.7 EON98955.1 - 1.4e-05 25.3 15.5 0.068 13.5 1.2 4.0 2 2 2 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EON98955.1 - 1.9e-05 24.6 12.1 0.013 15.5 0.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EON98955.1 - 0.00022 21.2 6.9 0.19 11.9 0.1 3.8 3 1 0 3 3 3 2 Zinc ribbon domain zf-C2HC_2 PF13913.6 EON98955.1 - 0.009 15.9 5.3 4 7.5 0.2 3.8 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf_ZIC PF18366.1 EON98955.1 - 0.01 15.9 8.5 11 6.2 0.5 4.5 3 2 1 4 4 4 0 Zic proteins zinc finger domain zf-Di19 PF05605.12 EON98955.1 - 0.013 15.8 0.4 0.013 15.8 0.4 3.4 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding OSTMP1 PF09777.9 EON98955.1 - 0.09 12.2 7.2 0.12 11.7 1.0 2.5 2 1 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor UBZ_FAAP20 PF15750.5 EON98955.1 - 0.097 12.6 0.9 0.94 9.5 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zinc-ribbons_6 PF07191.12 EON98955.1 - 0.53 10.3 12.2 4.5 7.3 1.1 4.1 2 2 1 3 3 3 0 zinc-ribbons AKAP95 PF04988.12 EON98955.1 - 1.8 8.8 6.1 1.3 9.2 0.5 2.3 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DUF629 PF04780.12 EON98955.1 - 3.3 6.1 9.2 8.3 4.8 0.8 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_9 PF16293.5 EON98955.1 - 6.8 6.6 8.3 19 5.2 0.1 3.2 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) Ribonuc_L-PSP PF01042.21 EON98956.1 - 1.8e-16 60.3 0.0 2.2e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP FAD_binding_1 PF00667.20 EON98957.1 - 7.7e-66 221.8 0.0 1.1e-65 221.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EON98957.1 - 1.4e-35 122.6 0.2 2.9e-35 121.6 0.2 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EON98957.1 - 2.4e-19 70.0 0.0 2.6e-18 66.7 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EON98957.1 - 0.081 13.2 0.0 0.32 11.2 0.0 2.1 1 0 0 1 1 1 0 Flavodoxin domain KH_8 PF17903.1 EON98958.1 - 4.6e-30 103.6 0.0 9e-30 102.6 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EON98958.1 - 0.024 14.5 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 KH domain F-box_4 PF15966.5 EON98959.1 - 0.0007 19.5 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 F-box F-box PF00646.33 EON98959.1 - 0.027 14.4 0.1 0.2 11.6 0.1 2.5 2 0 0 2 2 2 0 F-box domain LRR_8 PF13855.6 EON98959.1 - 0.28 11.0 3.5 6.3 6.6 0.0 4.4 5 1 0 5 5 5 0 Leucine rich repeat Cas9_REC PF16592.5 EON98960.1 - 0.06 12.1 0.0 0.066 11.9 0.0 1.0 1 0 0 1 1 1 0 REC lobe of CRISPR-associated endonuclease Cas9 Mlh1_C PF16413.5 EON98961.1 - 5.1e-102 340.9 0.0 9.9e-102 339.9 0.0 1.5 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EON98961.1 - 2.1e-34 117.7 0.0 3.6e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EON98961.1 - 5.5e-12 45.7 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EON98961.1 - 8.7e-07 29.4 0.0 1.7e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fungal_trans PF04082.18 EON98962.1 - 6.2e-05 22.1 3.9 0.22 10.5 2.9 3.3 2 1 0 2 2 2 2 Fungal specific transcription factor domain MOR2-PAG1_C PF14225.6 EON98963.1 - 7.4e-93 311.0 0.2 7.4e-93 311.0 0.2 2.8 4 0 0 4 4 4 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EON98963.1 - 4.6e-33 114.0 0.4 6.4e-19 67.2 0.1 2.3 2 0 0 2 2 2 2 Cell morphogenesis central region FAD_binding_3 PF01494.19 EON98964.1 - 7.6e-15 55.0 0.0 2.2e-14 53.5 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 EON98964.1 - 0.0042 16.2 0.0 0.01 14.9 0.0 1.6 2 0 0 2 2 2 1 Squalene epoxidase Amino_oxidase PF01593.24 EON98964.1 - 0.02 14.2 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Ank_2 PF12796.7 EON98965.1 - 4.5e-25 88.0 0.3 5.4e-12 46.1 0.2 4.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EON98965.1 - 9e-25 86.7 2.6 9.8e-06 26.0 0.0 6.2 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EON98965.1 - 2.1e-22 78.9 4.2 5.5e-08 32.9 0.3 4.5 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EON98965.1 - 7.8e-19 67.2 8.0 0.00028 21.2 0.0 7.9 8 0 0 8 8 8 3 Ankyrin repeat Ank_3 PF13606.6 EON98965.1 - 8.1e-18 62.7 1.0 0.013 16.0 0.0 7.8 9 0 0 9 9 9 4 Ankyrin repeat Cation_efflux PF01545.21 EON98966.1 - 8.2e-07 29.0 5.7 1.1e-06 28.6 5.7 1.1 1 0 0 1 1 1 1 Cation efflux family Cupin_2 PF07883.11 EON98967.1 - 0.00021 20.9 0.2 0.0024 17.6 0.3 2.4 2 1 0 2 2 2 1 Cupin domain FTA2 PF13095.6 EON98968.1 - 3.4e-68 229.5 0.0 4.5e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 WH2 PF02205.20 EON98969.1 - 0.00011 21.9 0.7 0.00026 20.7 0.7 1.7 1 0 0 1 1 1 1 WH2 motif CAP_N PF01213.19 EON98969.1 - 0.00042 19.9 0.1 0.00053 19.6 0.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal RCDG1 PF15725.5 EON98969.1 - 0.056 13.9 0.7 0.095 13.1 0.7 1.4 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Tape_meas_lam_C PF09718.10 EON98970.1 - 3 8.1 6.3 7 6.9 0.7 2.5 2 1 1 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) AdoMet_MTase PF07757.13 EON98971.1 - 2.2e-41 140.7 0.1 3.5e-41 140.0 0.1 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 EON98971.1 - 0.0026 17.8 0.0 0.015 15.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON98971.1 - 0.042 13.7 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MFS_MOT1 PF16983.5 EON98972.1 - 0.0013 19.2 0.1 0.0013 19.2 0.1 1.1 1 0 0 1 1 1 1 Molybdate transporter of MFS superfamily SelK_SelG PF10961.8 EON98972.1 - 0.48 11.1 2.3 4.5 7.9 2.3 2.2 1 1 0 1 1 1 0 Selenoprotein SelK_SelG GTP_EFTU PF00009.27 EON98973.1 - 4.8e-54 182.9 0.1 7.3e-54 182.3 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EON98973.1 - 3.4e-41 140.1 0.0 7.6e-41 138.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EON98973.1 - 5.2e-15 55.6 1.1 5.2e-15 55.6 1.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EON98973.1 - 0.00075 19.6 0.1 0.018 15.1 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EON98973.1 - 0.047 13.6 0.5 0.14 12.1 0.5 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 MAGE PF01454.19 EON98974.1 - 7.4e-70 235.0 0.1 1.2e-69 234.3 0.1 1.3 1 0 0 1 1 1 1 MAGE family Replic_Relax PF13814.6 EON98974.1 - 0.0026 17.9 0.0 0.0058 16.7 0.0 1.6 1 0 0 1 1 1 1 Replication-relaxation Lactamase_B PF00753.27 EON98975.1 - 6e-19 68.8 8.2 8.9e-19 68.3 8.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EON98975.1 - 1.9e-06 27.6 0.1 2.9e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ApbA PF02558.16 EON98976.1 - 1.6e-25 89.6 0.0 2.3e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EON98976.1 - 7.7e-14 52.0 0.0 1.5e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal TRP PF06011.12 EON98979.1 - 1.5e-109 366.6 18.9 2e-109 366.2 18.9 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EON98979.1 - 5.7e-36 123.9 0.0 9.1e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 ML-like domain DUF3328 PF11807.8 EON98980.1 - 2.5e-45 154.9 0.8 3.2e-45 154.6 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Med17 PF10156.9 EON98981.1 - 7.6e-83 278.7 4.5 1.3e-48 165.9 1.2 2.1 1 1 1 2 2 2 2 Subunit 17 of Mediator complex eIF-1a PF01176.19 EON98982.1 - 7.9e-21 73.6 0.1 1.1e-20 73.2 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 CBFD_NFYB_HMF PF00808.23 EON98983.1 - 1.3e-17 63.8 0.6 2.7e-17 62.8 0.6 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EON98983.1 - 0.00013 22.4 0.4 0.00035 20.9 0.1 1.7 1 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 HhH-GPD PF00730.25 EON98985.1 - 1.2e-07 32.1 0.0 2.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DEAD PF00270.29 EON98986.1 - 3.4e-39 134.4 0.0 5.8e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON98986.1 - 1.7e-25 89.5 0.3 6.2e-24 84.5 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON98986.1 - 1e-08 35.4 0.0 2.3e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EON98986.1 - 0.0056 16.3 0.0 0.0081 15.7 0.0 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF4844 PF16133.5 EON98986.1 - 0.019 15.5 0.8 0.045 14.3 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) ILEI PF15711.5 EON98987.1 - 0.17 12.4 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 Interleukin-like EMT inducer TFIIA PF03153.13 EON98988.1 - 0.015 15.3 6.5 0.019 15.0 6.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Noelin-1 PF12308.8 EON98988.1 - 0.59 10.2 3.2 1.7 8.7 2.9 2.0 1 1 0 1 1 1 0 Neurogenesis glycoprotein NOA36 PF06524.12 EON98988.1 - 5.4 6.2 12.1 9.5 5.4 12.1 1.4 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 EON98988.1 - 5.9 5.9 17.2 9 5.3 17.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Efg1 PF10153.9 EON98988.1 - 8.5 6.8 9.3 13 6.2 0.1 3.2 2 1 0 2 2 2 0 rRNA-processing protein Efg1 SUI1 PF01253.22 EON98989.1 - 1.7e-19 70.1 2.1 1.1e-18 67.5 2.1 1.9 1 1 0 1 1 1 1 Translation initiation factor SUI1 Caskin-Pro-rich PF16907.5 EON98989.1 - 0.022 15.3 0.1 0.028 14.9 0.1 1.2 1 0 0 1 1 1 0 Proline rich region of Caskin proteins DUF2575 PF10837.8 EON98989.1 - 0.042 14.1 0.0 0.072 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) DivIC PF04977.15 EON98991.1 - 2.9 7.7 5.9 2.7 7.8 0.2 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF1690 PF07956.11 EON98992.1 - 4.2e-45 153.6 11.3 4.8e-45 153.4 11.3 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF4653 PF15546.6 EON98992.1 - 0.0068 16.1 3.3 0.0099 15.5 3.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4653) DUF2407_C PF13373.6 EON98992.1 - 0.16 12.2 0.1 0.16 12.2 0.1 2.0 1 1 1 2 2 2 0 DUF2407 C-terminal domain XRN_M PF17846.1 EON98992.1 - 0.25 10.3 6.1 0.31 9.9 6.1 1.0 1 0 0 1 1 1 0 Xrn1 helical domain XhlA PF10779.9 EON98992.1 - 0.7 10.1 3.4 1.4 9.2 2.7 1.9 1 1 0 1 1 1 0 Haemolysin XhlA Golgin_A5 PF09787.9 EON98992.1 - 0.71 9.3 13.6 1.3 8.4 13.6 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 FUSC PF04632.12 EON98992.1 - 1 7.8 3.5 1.2 7.6 3.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phasin PF05597.11 EON98992.1 - 1.4 9.0 10.3 0.61 10.1 4.7 2.4 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4407 PF14362.6 EON98992.1 - 2.3 7.5 7.0 2.8 7.2 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSCB_C PF07743.13 EON98992.1 - 5.6 7.5 12.6 1.2e+02 3.2 12.6 2.7 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain Endonuc_Holl PF10107.9 EON98992.1 - 6.1 6.7 8.4 4.2 7.2 5.9 1.7 1 1 1 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase HEAT PF02985.22 EON98993.1 - 1e-13 50.3 13.1 0.014 15.6 0.0 9.9 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.6 EON98993.1 - 3.2e-13 49.8 7.8 1.2e-07 32.0 0.0 7.8 9 0 0 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.6 EON98993.1 - 8.6e-10 38.9 15.4 0.031 14.6 0.1 7.3 3 2 4 7 7 7 5 HEAT repeats IBN_N PF03810.19 EON98993.1 - 4.9e-05 23.2 2.6 4.9e-05 23.2 2.6 3.8 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.8 EON98993.1 - 0.003 17.2 4.7 5.2 6.5 0.1 5.4 3 1 4 7 7 7 1 CLASP N terminal DUF3385 PF11865.8 EON98993.1 - 0.005 16.8 1.6 7.4 6.4 0.0 4.3 3 2 1 5 5 5 2 Domain of unknown function (DUF3385) DUF1548 PF07579.11 EON98993.1 - 0.041 14.2 0.8 1.9 8.8 0.0 3.6 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1548) Dopey_N PF04118.14 EON98993.1 - 0.059 12.5 0.1 0.22 10.6 0.0 2.0 2 1 0 2 2 2 0 Dopey, N-terminal DUF2560 PF10834.8 EON98993.1 - 0.076 13.2 0.1 0.42 10.8 0.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2560) ABC1 PF03109.16 EON98995.1 - 8.6e-24 84.0 0.1 2.3e-23 82.6 0.0 1.7 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 EON98995.1 - 0.059 13.3 0.0 0.23 11.3 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family YpsA PF06908.11 EON98995.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 YspA SLOG family PAPS_reduct PF01507.19 EON98996.1 - 2.3e-44 151.5 0.4 7.4e-44 149.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family fn3_2 PF16893.5 EON98997.1 - 1e-38 131.3 0.0 1.6e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EON98997.1 - 1.1e-23 82.9 0.9 1.9e-23 82.1 0.9 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 EON98997.1 - 6.5e-13 48.4 0.0 1.2e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EON98997.1 - 8.7e-11 42.1 0.0 1.7e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EON98997.1 - 3.8e-05 24.0 0.0 8.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF3006 PF11213.8 EON98997.1 - 0.00049 20.3 0.7 0.0012 19.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) fn3 PF00041.21 EON98997.1 - 0.0007 19.9 0.0 0.0027 18.0 0.0 2.1 1 1 0 1 1 1 1 Fibronectin type III domain Tankyrase_bdg_C PF15327.6 EON98997.1 - 0.034 14.6 7.0 0.062 13.8 7.0 1.4 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain VIR_N PF15912.5 EON98997.1 - 0.43 10.1 10.3 0.69 9.5 10.3 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal SURF2 PF05477.11 EON98997.1 - 1 9.0 8.5 1.5 8.4 8.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) LAP1C PF05609.12 EON98997.1 - 3 6.8 10.5 5.2 6.1 10.5 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ferric_reduct PF01794.19 EON98999.1 - 8.4e-20 71.2 4.1 8.4e-20 71.2 4.1 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EON98999.1 - 9.1e-14 51.9 0.0 6.5e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EON98999.1 - 1.5e-12 47.5 0.1 4.4e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 EON98999.1 - 0.00099 19.7 0.0 0.22 12.2 0.0 2.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 EON98999.1 - 0.077 13.6 4.2 0.39 11.3 0.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) adh_short PF00106.25 EON99000.1 - 4.1e-12 46.0 0.0 5.2e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON99000.1 - 7.8e-08 32.1 0.0 0.00069 19.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON99000.1 - 0.0001 22.2 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 KR domain DNA_methylase PF00145.17 EON99001.1 - 2.1e-07 30.6 2.0 5.5e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Ribosomal_L13 PF00572.18 EON99001.1 - 0.13 12.5 0.2 0.22 11.8 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein L13 Amidohydro_1 PF01979.20 EON99003.1 - 3.5e-25 89.1 0.0 1.1e-24 87.4 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EON99003.1 - 6.2e-14 52.3 0.0 1.9e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Fungal_lectin PF07938.12 EON99004.1 - 2.8e-06 26.9 3.8 0.039 13.4 0.7 3.1 2 1 1 3 3 3 3 Fungal fucose-specific lectin SKG6 PF08693.10 EON99004.1 - 0.0026 17.1 1.2 0.0065 15.9 1.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 EON99004.1 - 0.03 13.2 1.6 0.045 12.6 1.6 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Rax2 PF12768.7 EON99004.1 - 0.034 13.6 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity PGF-CTERM PF18204.1 EON99004.1 - 0.052 13.5 1.7 0.15 12.0 1.7 1.9 1 0 0 1 1 1 0 PGF-CTERM motif PI3_PI4_kinase PF00454.27 EON99005.1 - 1.2e-51 176.0 0.0 1.9e-51 175.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EON99005.1 - 2.7e-17 62.3 0.0 5.4e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 EON99005.1 - 6.4e-17 61.8 11.2 4.8e-14 52.3 11.2 3.3 1 1 0 1 1 1 1 FAT domain FANCI_HD1 PF14679.6 EON99005.1 - 0.0086 16.0 0.0 8.7 6.4 0.0 4.3 5 0 0 5 5 5 1 FANCI helical domain 1 DUF2428 PF10350.9 EON99005.1 - 0.21 10.8 1.3 3.7 6.7 0.2 2.3 2 0 0 2 2 2 0 Putative death-receptor fusion protein (DUF2428) Malate_synthase PF01274.22 EON99006.1 - 1.3e-230 766.2 0.0 1.5e-230 766.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase zf-PARP PF00645.18 EON99007.1 - 1.3e-12 48.4 0.8 2.1e-11 44.5 0.8 2.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region TruD PF01142.18 EON99007.1 - 0.071 11.9 0.0 0.085 11.7 0.0 1.1 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) NAC PF01849.18 EON99009.1 - 4.5e-24 84.2 0.4 1.3e-23 82.7 0.1 1.9 2 0 0 2 2 2 1 NAC domain PGA2 PF07543.12 EON99009.1 - 2.4 8.1 8.1 7.9 6.5 2.4 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 Fungal_trans PF04082.18 EON99010.1 - 1e-09 37.8 0.1 1.7e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Robl_LC7 PF03259.17 EON99011.1 - 2.3e-11 43.3 0.0 2.3e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Dioxygenase_C PF00775.21 EON99012.1 - 1.8e-44 151.3 0.0 2.6e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EON99012.1 - 1.3e-31 108.3 0.0 3.6e-31 106.8 0.0 1.8 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EON99012.1 - 0.00025 21.3 0.0 0.00076 19.7 0.0 1.8 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF824 PF05688.11 EON99012.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) Big_1 PF02369.16 EON99012.1 - 0.11 12.5 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) GvpD PF07088.11 EON99012.1 - 0.12 11.0 0.0 0.23 10.0 0.0 1.4 2 0 0 2 2 2 0 GvpD gas vesicle protein TTR-52 PF01060.23 EON99012.1 - 0.15 12.7 0.0 0.33 11.7 0.0 1.5 1 0 0 1 1 1 0 Transthyretin-like family SpaA PF17802.1 EON99012.1 - 0.19 12.0 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 Prealbumin-like fold domain SEN1_N PF12726.7 EON99013.1 - 1.2e-95 321.4 0.0 1.5e-95 321.0 0.0 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 EON99013.1 - 7.9e-70 235.6 1.1 7.9e-70 235.6 1.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EON99013.1 - 2.5e-62 210.0 0.0 5.3e-62 209.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON99013.1 - 2.5e-09 37.1 0.5 1.3e-05 25.0 0.3 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EON99013.1 - 3.1e-09 37.3 0.0 1e-08 35.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EON99013.1 - 4.2e-07 30.0 0.2 0.014 15.1 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 EON99013.1 - 2.9e-06 27.0 0.1 0.0011 18.6 0.1 2.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 EON99013.1 - 0.043 13.7 0.2 4.1 7.2 0.1 2.9 2 1 0 2 2 2 0 Helicase ResIII PF04851.15 EON99013.1 - 0.056 13.4 0.5 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.29 EON99013.1 - 0.098 13.1 0.2 0.32 11.4 0.2 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EON99013.1 - 1.8 9.0 4.0 0.92 10.0 0.7 2.2 2 1 0 2 2 2 0 AAA domain Ank_2 PF12796.7 EON99014.1 - 1.3e-43 147.4 0.0 4e-14 53.0 0.0 5.0 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EON99014.1 - 3.7e-37 126.2 0.1 8.5e-08 32.6 0.0 8.2 4 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EON99014.1 - 4e-25 87.5 6.9 6.4e-06 26.3 0.1 7.2 4 2 4 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 EON99014.1 - 9.7e-25 85.9 10.3 0.0071 16.8 0.0 10.2 9 1 1 10 10 10 6 Ankyrin repeat Ank_3 PF13606.6 EON99014.1 - 3.6e-24 82.2 3.7 0.019 15.4 0.0 10.2 10 0 0 10 10 10 5 Ankyrin repeat Mt_ATP-synt_D PF05873.12 EON99017.1 - 6.4e-23 81.3 2.6 7.8e-23 81.0 2.6 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF2408 PF10303.9 EON99017.1 - 0.23 12.0 2.2 0.47 11.0 2.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) PFK PF00365.20 EON99018.1 - 3.1e-186 617.4 1.3 1.3e-104 349.5 1.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase DUF211 PF02680.14 EON99018.1 - 0.05 13.8 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 HMGL-like PF00682.19 EON99019.1 - 5.5e-79 265.4 0.0 1.2e-77 261.0 0.0 2.0 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 EON99019.1 - 4.1e-22 78.5 0.0 8.7e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Sigma_reg_N PF13800.6 EON99019.1 - 0.11 12.9 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal BetaGal_dom2 PF10435.9 EON99020.1 - 2.4e-60 203.4 0.1 4.8e-60 202.5 0.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 EON99020.1 - 1.4e-52 177.1 2.0 5.8e-27 94.5 0.1 2.5 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain Glyco_hydro_35 PF01301.19 EON99020.1 - 4.6e-26 92.2 0.0 7.3e-23 81.7 0.0 2.5 1 1 2 3 3 3 2 Glycosyl hydrolases family 35 BetaGal_dom3 PF13363.6 EON99020.1 - 3e-24 84.4 0.1 1.9e-23 81.8 0.1 2.2 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Aldedh PF00171.22 EON99021.1 - 2.4e-119 398.9 0.0 3e-119 398.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pectinesterase PF01095.19 EON99022.1 - 9.2e-25 87.0 1.1 5.7e-20 71.2 1.4 2.1 2 0 0 2 2 2 2 Pectinesterase RRM_1 PF00076.22 EON99023.1 - 4.2e-19 68.1 0.0 8.6e-12 44.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Adaptin_N PF01602.20 EON99024.1 - 6.4e-114 381.4 0.8 8.5e-114 381.0 0.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EON99024.1 - 1.1e-55 187.9 6.7 2.3e-55 186.9 6.7 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EON99024.1 - 4.7e-36 123.4 0.2 1.4e-35 121.9 0.2 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EON99024.1 - 1.8e-17 63.5 3.8 3.7e-12 46.5 0.1 5.5 3 1 3 6 6 6 1 HEAT repeats Cnd1 PF12717.7 EON99024.1 - 7.5e-07 29.3 10.9 0.027 14.5 0.1 5.0 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 EON99024.1 - 0.0021 18.6 1.1 1.5 9.7 0.0 4.3 4 0 0 4 4 3 1 PBS lyase HEAT-like repeat CLASP_N PF12348.8 EON99024.1 - 0.0087 15.6 5.9 0.027 14.0 0.1 3.4 4 0 0 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 EON99024.1 - 0.055 13.7 0.6 2.9 8.1 0.0 3.5 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Alpha_adaptin_C PF02296.16 EON99024.1 - 0.059 13.6 0.4 0.32 11.2 0.0 2.4 3 0 0 3 3 3 0 Alpha adaptin AP2, C-terminal domain DUF5010 PF16402.5 EON99024.1 - 0.11 11.3 0.0 0.46 9.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) HEAT PF02985.22 EON99024.1 - 0.46 10.9 10.2 2.4 8.6 0.2 5.3 6 0 0 6 6 6 0 HEAT repeat Ctr PF04145.15 EON99025.1 - 9.2e-30 104.2 0.1 1.1e-29 103.9 0.1 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Sugar_tr PF00083.24 EON99026.1 - 1.1e-29 103.7 13.1 1.2e-29 103.5 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON99026.1 - 2e-11 43.4 8.6 2.2e-11 43.3 8.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MNSV_P7B PF06692.11 EON99026.1 - 0.18 11.8 1.0 1.1 9.3 0.3 2.3 1 1 1 2 2 2 0 Melon necrotic spot virus P7B protein TYW3 PF02676.14 EON99027.1 - 8.2e-42 143.0 0.0 1.3e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 CBM-like PF14683.6 EON99027.1 - 2.9e-35 121.6 0.0 5.3e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 EON99027.1 - 4.3e-10 39.2 0.1 1.2e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 EON99027.1 - 8.8e-06 25.9 0.5 4.8e-05 23.6 0.1 2.3 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EON99027.1 - 0.035 14.1 0.2 0.43 10.6 0.1 2.3 2 0 0 2 2 2 0 CarboxypepD_reg-like domain Abhydrolase_3 PF07859.13 EON99028.1 - 0.00047 20.1 0.1 0.081 12.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON99028.1 - 0.0053 17.4 3.5 0.0075 16.9 3.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EON99028.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Thioesterase PF00975.20 EON99028.1 - 0.025 14.7 0.1 0.095 12.8 0.0 1.9 2 1 0 2 2 2 0 Thioesterase domain SLS PF14611.6 EON99029.1 - 2.9e-47 161.4 1.9 2.1e-46 158.5 1.1 2.2 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator GRAS PF03514.14 EON99029.1 - 0.031 13.2 0.1 0.1 11.5 0.0 1.8 2 0 0 2 2 2 0 GRAS domain family HIG_1_N PF04588.13 EON99030.1 - 0.049 13.9 1.8 2.7 8.3 0.1 3.2 3 0 0 3 3 3 0 Hypoxia induced protein conserved region DUF1634 PF07843.11 EON99030.1 - 0.055 13.6 1.7 1.8 8.7 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1634) ATP-sulfurylase PF01747.17 EON99031.1 - 4.8e-87 290.9 0.0 8e-87 290.2 0.0 1.4 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 EON99031.1 - 1.8e-58 196.9 0.1 2.7e-58 196.3 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 EON99031.1 - 9e-53 178.2 0.0 1.6e-52 177.4 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_18 PF13238.6 EON99031.1 - 0.073 13.6 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain bPH_6 PF10756.9 EON99031.1 - 0.088 12.9 0.1 0.32 11.1 0.1 2.0 1 0 0 1 1 1 0 Bacterial PH domain LigB PF02900.18 EON99032.1 - 1.9e-37 128.8 0.2 2.4e-37 128.5 0.2 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Ipi1_N PF12333.8 EON99033.1 - 2.2e-26 92.4 0.9 5.3e-26 91.2 0.0 2.1 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Lyase_1 PF00206.20 EON99034.1 - 3.4e-110 368.3 0.0 5e-110 367.7 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EON99034.1 - 3.8e-21 75.2 0.0 9.9e-21 73.9 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_zinc_N PF00107.26 EON99035.1 - 4.2e-06 26.8 0.0 9.7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase B12D PF06522.11 EON99036.1 - 0.11 12.3 1.2 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF4366 PF14283.6 EON99036.1 - 0.19 11.8 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) HAD PF12710.7 EON99037.1 - 2.6e-26 93.2 0.0 3.5e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EON99037.1 - 9.9e-18 65.2 1.0 1.6e-17 64.5 1.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EON99037.1 - 8.5e-10 38.8 0.7 6.8e-09 35.8 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EON99037.1 - 5.2e-05 23.4 0.3 0.00065 19.8 0.3 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EON99037.1 - 0.0042 16.5 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase DUF705 PF05152.12 EON99037.1 - 0.018 14.5 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Acid_PPase PF12689.7 EON99037.1 - 0.21 11.4 0.0 0.66 9.8 0.0 1.9 1 1 0 1 1 1 0 Acid Phosphatase p450 PF00067.22 EON99038.1 - 2.5e-44 151.8 0.0 3.3e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.22 EON99039.1 - 1.5e-106 356.7 0.0 1.7e-106 356.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EON99039.1 - 2e-06 27.4 0.0 3.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) EAF PF09816.9 EON99040.1 - 8.6e-23 80.7 0.4 1.6e-22 79.7 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Senescence_reg PF04520.13 EON99040.1 - 0.021 15.7 4.8 0.021 15.7 4.8 1.8 2 1 0 2 2 2 0 Senescence regulator DEAD PF00270.29 EON99041.1 - 2.1e-44 151.4 0.0 3.2e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON99041.1 - 4.8e-28 97.7 0.0 9e-26 90.4 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EON99041.1 - 0.027 14.5 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EON99041.1 - 0.033 12.9 0.0 0.05 12.3 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain PhoLip_ATPase_C PF16212.5 EON99042.1 - 4.8e-77 259.1 29.8 4.8e-77 259.1 29.8 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EON99042.1 - 3e-19 68.5 1.5 3e-19 68.5 1.5 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EON99042.1 - 4.4e-14 52.3 1.5 1.2e-13 51.0 0.0 2.4 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EON99042.1 - 3.5e-12 47.1 2.9 1.1e-08 35.6 0.7 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EON99042.1 - 1.5e-05 24.6 0.0 0.00016 21.2 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EON99042.1 - 0.005 16.6 0.4 0.022 14.5 0.4 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Clenterotox PF03505.14 EON99042.1 - 0.086 12.4 0.3 0.18 11.4 0.3 1.4 1 0 0 1 1 1 0 Clostridium enterotoxin Prominin PF05478.11 EON99042.1 - 4.7 5.0 5.1 0.44 8.4 0.2 1.6 2 0 0 2 2 2 0 Prominin BcrAD_BadFG PF01869.20 EON99043.1 - 0.0017 17.9 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family EI24 PF07264.11 EON99045.1 - 3.3e-15 56.8 9.0 6.1e-15 55.9 9.0 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) UPF0016 PF01169.19 EON99046.1 - 1.1e-40 137.8 23.2 2.6e-20 72.5 6.5 2.4 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF2070 PF09843.9 EON99046.1 - 0.052 11.8 0.7 0.095 11.0 0.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Tetraspanin PF00335.20 EON99047.1 - 0.0027 17.4 6.9 0.0046 16.7 6.9 1.3 1 1 0 1 1 1 1 Tetraspanin family COX4 PF02936.14 EON99047.1 - 0.3 11.1 1.1 0.56 10.2 0.4 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Pyrid_oxidase_2 PF13883.6 EON99048.1 - 1.1e-43 149.2 0.0 2.1e-43 148.2 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TPP_enzyme_C PF02775.21 EON99049.1 - 1e-15 57.8 0.1 1.7e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 EON99049.1 - 8.6e-12 45.0 0.0 4.7e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EON99049.1 - 6.4e-10 38.9 0.0 1.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Phosphodiest PF01663.22 EON99050.1 - 6.1e-67 226.7 5.3 1.9e-41 142.9 0.1 2.0 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EON99050.1 - 0.016 14.6 0.0 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 Sulfatase Metalloenzyme PF01676.18 EON99050.1 - 0.017 14.5 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily PglZ PF08665.12 EON99050.1 - 0.092 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 PglZ domain DUF229 PF02995.17 EON99050.1 - 0.17 10.5 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Glyco_hydro_28 PF00295.17 EON99052.1 - 7.4e-49 166.6 8.9 1e-48 166.1 8.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 zf-CCCH PF00642.24 EON99053.1 - 0.015 15.2 6.8 0.044 13.7 6.2 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EON99053.1 - 0.04 14.6 0.6 0.11 13.2 0.6 1.8 1 0 0 1 1 1 0 Torus domain zf-CCCH_3 PF15663.5 EON99053.1 - 0.26 11.5 2.7 0.57 10.4 1.9 2.0 1 1 1 2 2 2 0 Zinc-finger containing family zf_CCCH_4 PF18345.1 EON99053.1 - 2 8.6 13.1 0.69 10.1 9.6 2.0 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_4 PF18044.1 EON99053.1 - 2 8.3 10.7 18 5.2 8.8 2.3 2 0 0 2 2 2 0 CCCH-type zinc finger HTH_5 PF01022.20 EON99054.1 - 0.23 11.4 0.0 0.45 10.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family WH1 PF00568.23 EON99055.1 - 9.8e-29 99.5 0.4 1.5e-28 98.9 0.4 1.3 1 0 0 1 1 1 1 WH1 domain DUF3288 PF11691.8 EON99055.1 - 0.011 15.7 0.1 0.97 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3288) SF3b10 PF07189.11 EON99056.1 - 4.2e-38 129.3 0.0 5e-38 129.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Glyco_hydro_26 PF02156.15 EON99056.1 - 0.1 12.0 0.0 0.11 11.9 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 Abhydrolase_2 PF02230.16 EON99057.1 - 3.7e-59 200.2 0.0 4.4e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EON99057.1 - 1.7e-07 30.8 0.4 0.001 18.4 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON99057.1 - 2.7e-06 28.1 0.3 0.00015 22.4 0.5 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 EON99057.1 - 1.4e-05 24.9 0.0 0.00015 21.5 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 EON99057.1 - 8.1e-05 22.6 0.0 0.044 13.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EON99057.1 - 0.00019 21.2 0.2 0.69 9.5 0.1 3.0 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EON99057.1 - 0.00091 18.8 0.9 0.023 14.2 0.0 2.5 2 1 1 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 EON99057.1 - 0.0022 17.6 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF2974 PF11187.8 EON99057.1 - 0.073 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Cutinase PF01083.22 EON99057.1 - 0.23 11.4 0.0 0.47 10.4 0.0 1.5 1 0 0 1 1 1 0 Cutinase Glyco_hydro_76 PF03663.14 EON99058.1 - 4e-161 536.6 23.2 4.7e-161 536.3 23.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 NYN PF01936.18 EON99059.1 - 1.9e-11 44.7 0.0 3.4e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 NYN domain Cyclin PF08613.11 EON99060.1 - 5.8e-07 30.0 1.2 1.4e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EON99060.1 - 0.0016 18.2 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Syntaxin-6_N PF09177.11 EON99060.1 - 0.056 14.0 0.0 0.71 10.5 0.0 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal MEDS PF14417.6 EON99062.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain SRF-TF PF00319.18 EON99063.1 - 4.5e-21 74.1 0.1 6.1e-21 73.6 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDP-OH_P_transf PF01066.21 EON99064.1 - 1.7e-17 63.9 0.1 1.7e-17 63.9 0.1 3.5 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase bZIP_1 PF00170.21 EON99065.1 - 1.2e-07 31.7 12.4 2.1e-07 30.9 12.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 EON99065.1 - 3.5e-06 27.0 2.1 0.0017 18.2 0.0 2.4 1 1 1 2 2 2 2 Transcription factor PAP1 bZIP_Maf PF03131.17 EON99065.1 - 9.6e-05 22.8 7.4 9.6e-05 22.8 7.4 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor SHE3 PF17078.5 EON99065.1 - 0.00013 21.8 2.7 0.00019 21.2 2.7 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 ADIP PF11559.8 EON99065.1 - 0.014 15.5 7.4 0.014 15.5 7.4 1.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.19 EON99065.1 - 0.023 12.6 0.2 0.031 12.2 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.13 EON99065.1 - 0.03 14.3 5.2 0.031 14.3 5.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Atg14 PF10186.9 EON99065.1 - 0.058 12.5 1.1 0.069 12.2 1.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_2 PF07716.15 EON99065.1 - 0.48 10.5 15.5 8.3 6.6 15.5 2.4 1 1 0 1 1 1 0 Basic region leucine zipper GvpL_GvpF PF06386.11 EON99065.1 - 1.9 8.4 7.1 3 7.7 7.1 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF SNF2_N PF00176.23 EON99067.1 - 4.9e-59 199.8 0.0 1.5e-58 198.2 0.0 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EON99067.1 - 2e-17 63.5 0.0 4.1e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EON99067.1 - 4.9e-09 35.9 1.4 4.9e-09 35.9 1.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EON99067.1 - 9.1e-09 35.1 2.7 2e-08 34.0 2.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EON99067.1 - 4.3e-08 32.9 3.8 9.9e-08 31.7 3.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EON99067.1 - 1.1e-07 31.7 1.7 2.6e-07 30.6 1.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EON99067.1 - 3.4e-07 30.5 3.9 7.9e-07 29.3 3.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EON99067.1 - 2.2e-06 27.5 2.9 6e-06 26.1 2.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 EON99067.1 - 2.3e-06 27.7 0.1 1.3e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 EON99067.1 - 1.1e-05 25.4 4.6 2.9e-05 24.1 4.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING SDA1 PF05285.12 EON99067.1 - 0.022 14.2 19.9 0.034 13.6 19.9 1.2 1 0 0 1 1 1 0 SDA1 Baculo_IE-1 PF05290.11 EON99067.1 - 0.088 12.8 2.5 0.087 12.8 0.4 1.9 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 EON99067.1 - 0.098 12.5 4.9 0.69 9.7 5.3 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Nop14 PF04147.12 EON99067.1 - 0.14 10.3 23.3 0.21 9.8 23.3 1.1 1 0 0 1 1 1 0 Nop14-like family DZR PF12773.7 EON99067.1 - 0.34 11.0 4.3 0.71 9.9 4.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon Prok-RING_4 PF14447.6 EON99067.1 - 0.61 10.0 8.1 7.1 6.6 8.5 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF4806 PF16064.5 EON99067.1 - 1 9.7 3.5 2.3 8.5 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) BUD22 PF09073.10 EON99067.1 - 1.2 8.4 22.4 1.8 7.8 22.4 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 EON99067.1 - 6.9 4.6 29.1 13 3.7 29.1 1.4 1 0 0 1 1 1 0 DNA polymerase phi Myb_DNA-binding PF00249.31 EON99068.1 - 0.0091 16.2 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EON99068.1 - 0.035 14.3 0.2 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF1438 PF07270.11 EON99068.1 - 0.11 12.6 2.2 0.26 11.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1438) Myb_DNA-bind_6 PF13921.6 EON99068.1 - 0.17 12.2 0.1 0.37 11.1 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain PI3K_1B_p101 PF10486.9 EON99068.1 - 0.53 8.0 4.8 0.25 9.1 1.0 1.9 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ferric_reduct PF01794.19 EON99070.1 - 2e-24 86.1 11.4 4.2e-24 85.0 8.2 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EON99070.1 - 2.5e-18 66.7 0.0 4.4e-16 59.4 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EON99070.1 - 9.9e-08 32.0 0.0 3.1e-06 27.2 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EON99070.1 - 0.072 13.7 0.0 0.19 12.4 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Septin PF00735.18 EON99072.1 - 6.7e-31 107.6 0.0 2.8e-11 43.2 0.0 3.1 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.23 EON99072.1 - 6.2e-05 23.1 0.0 0.0022 18.0 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EON99072.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EON99072.1 - 0.082 13.4 0.0 0.17 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EON99072.1 - 0.16 12.0 0.2 0.95 9.5 0.0 2.3 2 1 0 2 2 2 0 Dynamin family Pkinase PF00069.25 EON99073.1 - 3.9e-68 229.7 0.2 7e-67 225.6 0.2 2.2 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 EON99073.1 - 1.2e-42 144.4 0.4 2.2e-42 143.5 0.4 1.5 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 EON99073.1 - 4.7e-37 127.7 0.2 6.7e-35 120.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EON99073.1 - 1.9e-07 30.4 0.0 3.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EON99073.1 - 7.3e-06 25.5 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EON99073.1 - 0.00032 20.7 0.2 0.0032 17.4 0.1 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EON99073.1 - 0.011 15.3 0.2 0.03 13.9 0.2 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase SSF PF00474.17 EON99074.1 - 1.2e-09 37.5 28.2 1.5e-08 33.9 28.0 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family IMD PF08397.11 EON99075.1 - 0.00038 19.9 2.4 0.11 11.9 0.4 2.3 2 0 0 2 2 2 2 IRSp53/MIM homology domain Skp1 PF01466.19 EON99075.1 - 0.034 14.3 0.4 0.083 13.0 0.4 1.6 1 0 0 1 1 1 0 Skp1 family, dimerisation domain TMCO5 PF14992.6 EON99075.1 - 0.15 11.6 1.7 0.23 11.0 1.7 1.2 1 0 0 1 1 1 0 TMCO5 family Rab_bind PF16704.5 EON99075.1 - 0.34 11.0 3.1 0.65 10.1 0.3 2.4 2 0 0 2 2 2 0 Rab binding domain APG6_N PF17675.1 EON99075.1 - 3 8.4 13.0 3 8.4 1.9 3.1 3 1 0 3 3 3 0 Apg6 coiled-coil region EOS1 PF12326.8 EON99076.1 - 3.6e-15 56.3 7.3 3.6e-15 56.3 7.3 2.3 2 1 1 3 3 3 1 N-glycosylation protein Nodulin-like PF06813.13 EON99076.1 - 0.026 14.0 2.3 0.17 11.3 1.0 2.1 1 1 1 2 2 2 0 Nodulin-like NADH_dehy_S2_C PF06444.11 EON99076.1 - 0.029 14.9 3.1 0.029 14.9 3.1 2.6 3 1 0 3 3 3 0 NADH dehydrogenase subunit 2 C-terminus ADH_zinc_N PF00107.26 EON99078.1 - 5.9e-08 32.7 2.6 1.1e-07 31.9 2.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON99078.1 - 2.9e-06 27.1 0.0 5.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 EON99078.1 - 0.12 11.8 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family vATP-synt_E PF01991.18 EON99080.1 - 2.2e-69 232.8 14.8 2.6e-69 232.6 14.8 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Methyltransf_7 PF03492.15 EON99080.1 - 0.011 15.0 3.3 0.051 12.8 3.8 1.7 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase CinA_KH PF18146.1 EON99080.1 - 0.049 13.8 0.5 1.5 9.0 0.1 2.7 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain Transposase_24 PF03004.14 EON99080.1 - 1.2 9.2 7.6 1 9.4 0.1 2.7 1 1 1 2 2 2 0 Plant transposase (Ptta/En/Spm family) Mid2 PF04478.12 EON99081.1 - 1.1e-06 28.5 2.1 1.1e-06 28.5 2.1 2.4 1 1 1 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 EON99081.1 - 0.01 15.2 0.4 0.034 13.5 0.4 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain AOC_like PF18678.1 EON99081.1 - 0.024 14.2 0.1 0.04 13.5 0.1 1.4 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain PAP_PilO PF06864.12 EON99081.1 - 0.04 12.7 0.3 0.081 11.7 0.0 1.6 2 0 0 2 2 2 0 Pilin accessory protein (PilO) Apt1 PF10351.9 EON99081.1 - 0.13 11.1 9.4 0.18 10.6 9.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF572 PF04502.13 EON99081.1 - 2 7.9 8.9 2.9 7.4 8.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) CorA PF01544.18 EON99082.1 - 1.5e-13 50.8 0.1 2.5e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CENP-O PF09496.10 EON99083.1 - 3.4e-73 246.1 0.1 5.7e-73 245.4 0.0 1.4 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component p450 PF00067.22 EON99084.1 - 9.1e-49 166.4 0.0 1.2e-48 166.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SMC_N PF02463.19 EON99085.1 - 6.3e-26 91.2 0.0 1.6e-25 89.9 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EON99085.1 - 7.9e-17 62.4 52.6 5.6e-11 43.3 23.0 4.7 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 EON99085.1 - 5.8e-07 29.6 0.0 0.0098 15.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EON99085.1 - 4e-06 26.8 0.0 4e-06 26.8 0.0 3.3 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EON99085.1 - 0.022 14.5 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EON99085.1 - 0.029 14.8 0.5 0.74 10.2 0.0 3.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MtrB PF05440.12 EON99085.1 - 0.13 12.6 0.2 0.8 10.2 0.2 2.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B TetR_C_4 PF08359.11 EON99085.1 - 0.32 11.1 9.5 0.61 10.2 1.0 3.0 2 0 0 2 2 2 0 YsiA-like protein, C-terminal region AAA_27 PF13514.6 EON99085.1 - 0.47 10.0 0.0 0.47 10.0 0.0 5.2 5 1 1 6 6 6 0 AAA domain CENP-B_dimeris PF09026.10 EON99085.1 - 3.6 8.0 12.1 11 6.4 12.1 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PAM2 PF07145.15 EON99086.1 - 0.00022 20.7 10.6 0.63 9.9 1.5 4.5 4 0 0 4 4 4 3 Ataxin-2 C-terminal region Hemagglutinin PF00509.18 EON99086.1 - 2.4 6.5 3.8 4.6 5.5 3.8 1.4 1 0 0 1 1 1 0 Haemagglutinin Ribosomal_L14e PF01929.17 EON99088.1 - 1.1e-33 115.5 5.2 1.6e-33 115.0 5.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EON99088.1 - 0.0045 16.9 0.1 0.025 14.5 0.0 2.2 2 0 0 2 2 2 1 KOW motif SUR7 PF06687.12 EON99089.1 - 1.2e-28 100.2 11.9 1.7e-28 99.7 11.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2298 PF10060.9 EON99089.1 - 0.026 13.2 2.4 0.043 12.6 2.4 1.3 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) 7TM_GPCR_Srd PF10317.9 EON99089.1 - 0.052 12.7 7.7 0.094 11.9 7.7 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd DUF5373 PF17343.2 EON99089.1 - 0.055 13.3 2.1 0.093 12.6 0.9 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5373) Trp_oprn_chp PF09534.10 EON99089.1 - 0.15 11.8 3.0 3.7 7.3 0.0 2.7 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4381 PF14316.6 EON99089.1 - 0.16 12.2 0.1 0.16 12.2 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) 7TMR-DISM_7TM PF07695.11 EON99089.1 - 2.4 8.0 20.2 0.35 10.7 12.5 2.0 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF5381 PF17353.2 EON99089.1 - 3.8 7.2 6.5 6.3 6.5 6.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5381) Polysacc_deac_1 PF01522.21 EON99091.1 - 2.5e-08 33.9 0.0 5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase VIGSSK PF14773.6 EON99092.1 - 2e-07 31.0 7.2 18 5.5 0.0 7.3 1 1 7 8 8 8 4 Helicase-associated putative binding domain, C-terminal DUF4733 PF15878.5 EON99092.1 - 0.00063 20.2 8.1 7.3 7.1 0.1 4.1 1 1 3 4 4 4 4 Domain of unknown function (DUF4733) BslA PF17735.1 EON99092.1 - 0.091 12.8 0.1 91 3.1 0.0 3.2 1 1 4 5 5 5 0 Biofilm surface layer A aGPT-Pplase1 PF18723.1 EON99093.1 - 0.068 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Acatn PF13000.7 EON99094.1 - 8.9e-166 552.6 16.6 2.5e-84 283.8 8.5 3.3 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DUF3951 PF13131.6 EON99094.1 - 0.016 15.4 0.5 0.13 12.5 0.5 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) ERCC4 PF02732.15 EON99095.1 - 3.4e-19 69.6 0.0 7.4e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain Tim44 PF04280.15 EON99097.1 - 1.2e-08 35.2 0.0 2.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 EON99097.1 - 0.00038 19.6 0.0 0.00049 19.2 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein CCT_2 PF09425.10 EON99097.1 - 0.04 13.8 1.0 0.13 12.2 1.0 2.0 1 0 0 1 1 1 0 Divergent CCT motif Mem_trans PF03547.18 EON99097.1 - 0.15 10.4 0.0 1.4 7.2 0.0 1.9 2 0 0 2 2 2 0 Membrane transport protein NmrA PF05368.13 EON99098.1 - 3.5e-14 52.9 0.0 4.7e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EON99098.1 - 1.4e-10 41.4 0.0 2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GTP_EFTU PF00009.27 EON99099.1 - 1.4e-18 67.2 0.0 2.7e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EON99099.1 - 2.1e-09 37.6 1.0 1e-08 35.4 0.6 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 EON99099.1 - 0.0004 20.3 0.6 0.5 10.3 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EON99099.1 - 0.0013 18.8 0.4 0.0041 17.2 0.4 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EON99099.1 - 0.0053 16.5 0.4 0.34 10.6 0.1 3.1 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D3 PF03143.17 EON99099.1 - 0.03 14.6 0.0 0.082 13.2 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain Dynamin_N PF00350.23 EON99099.1 - 0.093 12.8 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Dynamin family Roc PF08477.13 EON99099.1 - 0.2 11.9 0.1 1.9 8.7 0.1 2.3 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase S1 PF00575.23 EON99101.1 - 1.3e-72 240.1 50.7 2.6e-14 53.3 1.2 13.0 13 0 0 13 13 13 9 S1 RNA binding domain RNase_II_C_S1 PF18614.1 EON99101.1 - 8.4e-05 22.4 7.2 2.8 8.0 0.0 6.1 5 0 0 5 5 5 2 RNase II-type exonuclease C-terminal S1 domain NRDE-2 PF08424.10 EON99101.1 - 9e-05 21.7 1.2 0.014 14.6 0.5 2.7 1 1 0 2 2 2 2 NRDE-2, necessary for RNA interference S1_2 PF13509.6 EON99101.1 - 0.00019 21.4 0.6 13 5.9 0.0 6.2 6 0 0 6 6 6 1 S1 domain Suf PF05843.14 EON99101.1 - 0.0046 17.0 8.1 0.2 11.6 0.5 3.8 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EON99101.1 - 0.0083 16.9 6.4 14 6.8 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat MRP-S35 PF10246.9 EON99101.1 - 0.014 15.3 0.2 2.9 7.9 0.0 3.9 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 TPR_19 PF14559.6 EON99101.1 - 0.031 14.8 0.0 6.1 7.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Pox_RNA_pol PF03293.14 EON99101.1 - 0.13 11.9 0.7 15 5.2 0.0 3.8 4 0 0 4 4 4 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit BPL_C PF02237.17 EON99101.1 - 0.13 12.2 0.5 1.8 8.5 0.0 3.2 4 0 0 4 4 4 0 Biotin protein ligase C terminal domain Methyltransf_11 PF08241.12 EON99102.1 - 7.1e-21 74.7 0.0 1.4e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON99102.1 - 7.4e-21 74.7 0.0 1.2e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON99102.1 - 3.2e-20 72.5 0.0 6.6e-20 71.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON99102.1 - 2.6e-14 53.4 0.0 3.9e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON99102.1 - 4.4e-12 46.6 0.0 6.8e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON99102.1 - 7.1e-11 41.9 0.0 3.2e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 EON99102.1 - 1.1e-07 31.1 0.0 1.7e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 EON99102.1 - 0.00018 21.1 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EON99102.1 - 0.0039 16.5 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 EON99102.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB ADH_zinc_N_2 PF13602.6 EON99102.1 - 0.053 14.6 0.0 0.098 13.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PrmA PF06325.13 EON99102.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EON99102.1 - 0.13 12.4 0.0 0.23 11.5 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 EON99102.1 - 0.26 11.2 0.0 0.37 10.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L34e PF01199.18 EON99105.1 - 6.4e-43 145.0 1.5 8.6e-43 144.6 1.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 EON99105.1 - 0.047 13.1 0.1 0.12 11.8 0.1 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FhuF_C PF11575.8 EON99105.1 - 1 9.3 4.8 5.2 7.1 0.2 2.8 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain ATG16 PF08614.11 EON99106.1 - 4.8e-54 183.6 20.9 5.5e-54 183.4 20.9 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 EON99106.1 - 8e-05 22.2 7.1 9.2e-05 22.1 7.1 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF4201 PF13870.6 EON99106.1 - 0.23 11.2 14.6 1.5 8.5 12.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 EON99106.1 - 0.61 8.9 14.6 0.18 10.7 12.0 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 EON99106.1 - 0.7 10.2 17.8 2.6 8.4 3.1 3.8 1 1 3 4 4 4 0 ABC transporter C-terminal domain GAS PF13851.6 EON99106.1 - 1.1 8.6 17.7 4.1 6.7 10.0 2.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 EON99106.1 - 1.4 7.9 10.3 2 7.4 10.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 EON99106.1 - 1.5 9.3 24.0 2.1e+02 2.4 22.3 2.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 EON99106.1 - 3.9 6.8 17.3 0.33 10.3 6.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EON99106.1 - 8.6 6.4 15.4 11 6.1 7.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LDB19 PF13002.7 EON99107.1 - 2.9e-34 118.5 0.1 5.9e-34 117.5 0.1 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 EON99107.1 - 0.0011 19.1 0.0 0.003 17.6 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Ribosomal_L27A PF00828.19 EON99108.1 - 1.6e-33 116.1 0.7 2.5e-33 115.5 0.7 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A PROCN PF08083.11 EON99109.1 - 1.6e-233 774.7 10.7 1.6e-233 774.7 10.7 2.0 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EON99109.1 - 5.3e-127 422.1 1.7 1.1e-126 421.1 1.7 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EON99109.1 - 3.5e-89 296.8 3.1 1.1e-88 295.1 2.0 2.5 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EON99109.1 - 2.1e-79 264.8 2.7 2.1e-79 264.8 2.7 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EON99109.1 - 2.6e-71 238.0 0.1 5.4e-71 236.9 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EON99109.1 - 2.1e-46 156.2 0.1 5.6e-46 154.8 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 EON99109.1 - 1.7e-44 150.7 0.3 5e-44 149.2 0.0 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain PX PF00787.24 EON99111.1 - 7e-18 64.7 0.0 1.5e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 PX domain Methylase_S PF01420.19 EON99111.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.2 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain Asp PF00026.23 EON99112.1 - 6.1e-62 209.8 0.1 7.4e-62 209.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EON99112.1 - 2e-14 54.2 0.7 2.4e-12 47.5 0.7 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EON99112.1 - 0.0055 17.3 0.1 0.52 11.0 0.0 3.0 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EON99112.1 - 0.11 13.0 0.0 0.95 10.1 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Corona_nucleoca PF00937.18 EON99113.1 - 0.16 11.0 9.5 0.038 13.0 5.6 2.0 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Fungal_trans PF04082.18 EON99114.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glyco_hydro_59 PF02057.15 EON99115.1 - 4.8e-12 45.7 0.3 7.7e-12 45.0 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 EON99115.1 - 4.9e-11 42.7 4.4 1.1e-10 41.6 4.4 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydr_30_2 PF14587.6 EON99115.1 - 7e-11 42.3 1.8 8.9e-11 42.0 0.4 1.9 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.16 EON99115.1 - 6.7e-07 28.6 0.1 8.7e-07 28.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain DUF1966 PF09260.11 EON99115.1 - 0.031 14.5 0.4 0.13 12.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1966) PBP1_TM PF14812.6 EON99116.1 - 0.026 14.9 6.2 0.026 14.9 6.2 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.13 EON99116.1 - 0.1 12.7 19.3 0.2 11.8 8.6 2.3 2 0 0 2 2 2 0 YL1 nuclear protein DUF4484 PF14831.6 EON99116.1 - 0.35 10.9 5.8 0.63 10.1 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) eIF3_subunit PF08597.10 EON99116.1 - 1.1 9.1 22.4 0.043 13.7 7.6 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit CENP-B_dimeris PF09026.10 EON99116.1 - 2.8 8.4 10.6 0.65 10.4 5.0 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PTPRCAP PF15713.5 EON99116.1 - 2.9 8.2 14.0 0.62 10.3 1.7 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF3140 PF11338.8 EON99117.1 - 1.5e-35 121.5 1.5 1.5e-35 121.5 1.5 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF3140) Hva1_TUDOR PF11160.8 EON99117.1 - 3.3e-14 52.8 2.8 3.3e-14 52.8 2.8 3.1 3 1 0 3 3 3 1 Hypervirulence associated proteins TUDOR domain AA_permease PF00324.21 EON99118.1 - 9.1e-93 311.4 36.5 1.2e-92 311.0 36.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON99118.1 - 1.4e-21 76.8 41.4 1.9e-21 76.4 40.7 1.5 1 1 0 1 1 1 1 Amino acid permease Ribosomal_S19e PF01090.19 EON99119.1 - 7.6e-59 197.3 0.1 8.6e-59 197.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_S6 PF01250.17 EON99120.1 - 1.2e-23 83.1 0.0 1.5e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 adh_short_C2 PF13561.6 EON99121.1 - 3.6e-12 46.4 1.8 4.4e-12 46.0 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON99121.1 - 4.8e-12 45.8 2.1 5.8e-12 45.5 2.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON99121.1 - 1.8e-05 24.7 0.7 2e-05 24.6 0.7 1.1 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 EON99121.1 - 0.00025 21.0 0.3 0.0003 20.7 0.3 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus 3HCDH_N PF02737.18 EON99121.1 - 0.0092 15.9 1.3 0.011 15.7 1.3 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EON99121.1 - 0.028 13.7 0.7 0.27 10.5 0.4 2.0 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Cullin_binding PF03556.15 EON99122.1 - 4.7e-35 120.6 2.7 6.7e-35 120.1 2.7 1.2 1 0 0 1 1 1 1 Cullin binding Chs7 PF12271.8 EON99123.1 - 1.3e-124 415.3 12.8 1.5e-124 415.1 12.8 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 EON99123.1 - 0.018 15.3 1.3 0.018 15.3 1.3 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) GLEYA PF10528.9 EON99124.1 - 2.1e-15 56.9 0.0 3.7e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 GLEYA domain FHA PF00498.26 EON99125.1 - 3.2e-15 56.2 0.0 5.3e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EON99125.1 - 3.3e-13 49.1 9.4 5.8e-13 48.3 9.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EON99125.1 - 2.1e-06 28.0 12.9 3.3e-06 27.3 12.9 1.3 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 EON99125.1 - 0.021 15.1 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain zf-rbx1 PF12678.7 EON99125.1 - 0.021 15.1 7.7 0.048 13.9 7.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EON99125.1 - 0.023 14.6 13.0 0.037 13.9 13.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EON99125.1 - 0.025 14.6 2.2 0.042 13.9 2.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EON99125.1 - 0.05 13.6 9.9 0.079 12.9 9.9 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EON99125.1 - 0.08 12.8 11.9 0.14 12.0 11.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CDC45 PF02724.14 EON99125.1 - 0.14 10.4 0.5 0.17 10.1 0.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Spt5_N PF11942.8 EON99125.1 - 0.22 12.5 6.3 0.57 11.2 6.3 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal zf-RING_UBOX PF13445.6 EON99125.1 - 0.33 11.0 12.0 0.67 10.0 12.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Sec_GG PF07549.14 EON99125.1 - 0.74 9.4 2.0 1 9.0 0.3 2.1 2 0 0 2 2 2 0 SecD/SecF GG Motif PIG-L PF02585.17 EON99126.1 - 2.5e-26 92.8 0.0 3.7e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase SNF2_N PF00176.23 EON99127.1 - 1.3e-72 244.4 0.0 1.7e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EON99127.1 - 5.6e-22 77.5 0.0 1.2e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EON99127.1 - 2.7e-15 56.7 0.0 5.4e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EON99127.1 - 0.00035 20.4 13.9 0.00071 19.4 13.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EON99127.1 - 0.00069 19.7 0.0 0.0018 18.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 EON99127.1 - 0.0041 16.9 9.2 0.0088 15.9 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EON99127.1 - 0.016 15.5 13.9 0.039 14.3 13.9 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 EON99127.1 - 0.024 14.5 11.1 0.045 13.6 11.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EON99127.1 - 0.27 11.3 11.8 0.55 10.3 11.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EON99127.1 - 2.9 7.9 11.9 12 6.0 12.2 2.0 1 1 1 2 2 2 0 zinc-RING finger domain Dehydratase_hem PF13816.6 EON99128.1 - 4.9e-88 295.5 0.0 5.6e-88 295.3 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase Amidoligase_2 PF12224.8 EON99129.1 - 2.7e-17 63.3 0.2 1.3e-15 57.8 0.2 2.2 1 1 0 1 1 1 1 Putative amidoligase enzyme Methyltransf_11 PF08241.12 EON99130.1 - 1.9e-18 66.9 0.0 3.3e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON99130.1 - 3.2e-18 66.2 0.0 5.6e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON99130.1 - 7e-16 58.4 0.0 9.4e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON99130.1 - 1.3e-10 41.4 0.0 1.6e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON99130.1 - 3.2e-10 39.8 0.0 4.5e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EON99130.1 - 2.4e-09 37.8 0.0 3.7e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EON99130.1 - 9.8e-08 31.6 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 EON99130.1 - 7.9e-05 22.6 0.0 0.001 19.0 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.12 EON99130.1 - 0.00013 21.7 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 EON99130.1 - 0.00024 20.6 0.0 0.00034 20.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EON99130.1 - 0.00031 20.3 0.0 0.0005 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EON99130.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 EON99130.1 - 0.023 14.0 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 EON99130.1 - 0.044 13.8 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 EON99130.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 EON99130.1 - 0.12 11.8 0.0 0.65 9.5 0.0 2.1 3 0 0 3 3 3 0 Putative methyltransferase Peptidase_M16_C PF05193.21 EON99131.1 - 3.6e-57 193.3 0.0 7.4e-57 192.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EON99131.1 - 9.8e-42 142.4 0.0 3.4e-41 140.7 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF4688 PF15752.5 EON99131.1 - 0.028 13.7 1.0 0.077 12.2 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4688) Hemerythrin PF01814.23 EON99132.1 - 2.5e-12 47.5 1.1 3.8e-12 46.9 1.1 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DOT1 PF08123.13 EON99133.1 - 6.3e-73 244.7 0.0 8.2e-73 244.3 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Abhydrolase_1 PF00561.20 EON99134.1 - 7.3e-19 68.4 0.0 1.4e-18 67.5 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON99134.1 - 7.6e-17 62.7 3.5 1.4e-16 61.8 3.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON99134.1 - 4e-12 45.9 0.0 5.7e-11 42.1 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DSPc PF00782.20 EON99134.1 - 3.5e-09 36.6 0.0 7.7e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 EON99134.1 - 1.2e-06 28.8 0.1 3e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 Thioesterase domain PTPlike_phytase PF14566.6 EON99134.1 - 0.0001 22.5 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate PGAP1 PF07819.13 EON99134.1 - 0.00083 19.1 0.0 0.021 14.5 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein FSH1 PF03959.13 EON99134.1 - 0.005 16.5 0.0 0.6 9.7 0.0 2.3 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Palm_thioest PF02089.15 EON99134.1 - 0.0084 16.0 0.0 0.027 14.3 0.0 1.8 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Ser_hydrolase PF06821.13 EON99134.1 - 0.025 14.4 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase Y_phosphatase PF00102.27 EON99134.1 - 0.042 13.4 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Chlorophyllase2 PF12740.7 EON99134.1 - 0.06 12.2 0.0 0.16 10.9 0.0 1.6 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.20 EON99134.1 - 0.082 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 EON99134.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.14 EON99134.1 - 0.21 11.1 0.0 0.58 9.6 0.0 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) DUF202 PF02656.15 EON99135.1 - 0.23 11.9 0.0 0.23 11.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF202) FAD_binding_3 PF01494.19 EON99136.1 - 9.8e-20 71.1 0.0 7.1e-19 68.3 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EON99136.1 - 1.2e-09 38.2 2.8 0.00087 19.0 2.8 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON99136.1 - 2.7e-07 30.1 0.8 0.0031 16.8 0.4 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON99136.1 - 7e-06 26.2 0.7 4.1e-05 23.7 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EON99136.1 - 1.2e-05 24.6 0.2 2.8e-05 23.4 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EON99136.1 - 0.0012 18.0 0.0 0.0021 17.2 0.0 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 EON99136.1 - 0.0012 17.6 0.4 0.016 13.9 0.4 2.0 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EON99136.1 - 0.0016 18.9 0.0 0.14 12.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 EON99136.1 - 0.022 14.6 0.1 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 Rossmann-like domain ApbA PF02558.16 EON99136.1 - 0.12 12.1 0.2 1.6 8.3 0.2 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 EON99136.1 - 0.15 11.6 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aldedh PF00171.22 EON99137.1 - 4.1e-150 500.3 0.8 4.6e-150 500.2 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EON99137.1 - 0.0013 18.2 0.0 0.0064 16.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) DUF4054 PF13262.6 EON99137.1 - 0.076 13.1 0.2 0.27 11.3 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) Glyco_hydro_28 PF00295.17 EON99138.1 - 4.4e-30 104.8 9.7 5.9e-30 104.4 9.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 ADH_zinc_N PF00107.26 EON99139.1 - 1.1e-06 28.6 0.0 1.6e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EON99139.1 - 8.8e-05 22.4 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase SnoaL_4 PF13577.6 EON99140.1 - 3.6e-09 36.8 0.0 5.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain MDM10 PF12519.8 EON99141.1 - 3.5e-163 543.8 0.0 2.5e-162 541.0 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 EON99141.1 - 0.18 11.3 0.1 11 5.4 0.1 3.0 3 0 0 3 3 3 0 Eukaryotic porin adh_short PF00106.25 EON99142.1 - 9.2e-21 74.2 1.0 3.8e-19 68.9 0.5 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON99142.1 - 2e-14 53.7 0.8 2.5e-11 43.6 0.9 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON99142.1 - 6e-12 45.8 0.3 1.1e-11 44.9 0.3 1.5 1 0 0 1 1 1 1 KR domain Microtub_bd PF16796.5 EON99142.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Microtubule binding Shikimate_DH PF01488.20 EON99142.1 - 0.13 12.4 0.3 0.28 11.2 0.2 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Mis14 PF08641.12 EON99143.1 - 0.069 13.5 0.4 0.088 13.1 0.4 1.4 1 1 0 1 1 1 0 Kinetochore protein Mis14 like DUF3464 PF11947.8 EON99144.1 - 0.047 13.4 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 FAM176 PF14851.6 EON99144.1 - 0.069 12.8 4.6 0.13 11.9 0.5 2.2 2 0 0 2 2 2 0 FAM176 family DUF3246 PF11596.8 EON99144.1 - 0.074 12.5 0.9 0.093 12.1 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Codanin-1_C PF15296.6 EON99144.1 - 0.15 12.1 2.3 1.3 9.1 2.3 2.1 1 1 0 1 1 1 0 Codanin-1 C-terminus NPDC1 PF06809.11 EON99144.1 - 0.16 11.0 0.1 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) RXT2_N PF08595.11 EON99144.1 - 0.17 11.9 2.9 0.22 11.5 2.9 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Sporozoite_P67 PF05642.11 EON99144.1 - 0.28 9.2 1.5 0.34 8.9 1.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 EON99144.1 - 1.1 8.5 4.0 1.4 8.1 4.0 1.1 1 0 0 1 1 1 0 NOA36 protein Herpes_UL32 PF06070.11 EON99144.1 - 3 5.5 7.2 3.7 5.2 7.2 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Scytalone_dh PF02982.14 EON99145.1 - 7.4e-91 302.1 1.9 8.4e-91 301.9 1.9 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 EON99145.1 - 7.6e-07 29.3 0.6 1.1e-06 28.8 0.6 1.2 1 0 0 1 1 1 1 SnoaL-like domain FAR1 PF03101.15 EON99146.1 - 2e-05 25.2 0.3 3.7e-05 24.3 0.3 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain XhlA PF10779.9 EON99146.1 - 0.00086 19.5 0.2 1.5 9.1 0.0 2.6 2 0 0 2 2 2 2 Haemolysin XhlA Sugarporin_N PF11471.8 EON99146.1 - 0.015 15.3 0.1 2 8.4 0.0 2.4 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension CLZ PF16526.5 EON99146.1 - 0.017 15.4 0.2 3.9 7.9 0.0 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AFT PF08731.11 EON99146.1 - 0.019 15.4 0.4 0.041 14.3 0.4 1.7 1 1 0 1 1 1 0 Transcription factor AFT Snapin_Pallidin PF14712.6 EON99146.1 - 0.038 14.4 0.5 3.6 8.1 0.1 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Cep57_CLD PF14073.6 EON99146.1 - 0.047 13.7 0.1 2 8.4 0.1 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 DUF1664 PF07889.12 EON99146.1 - 0.098 12.7 0.8 0.36 10.9 0.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SKA2 PF16740.5 EON99146.1 - 0.1 12.4 0.1 0.69 9.7 0.0 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 ABC_tran_CTD PF16326.5 EON99146.1 - 0.14 12.4 0.1 2.3 8.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain Nsp1_C PF05064.13 EON99146.1 - 0.18 11.6 0.2 5.5 6.8 0.1 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region HSBP1 PF06825.12 EON99146.1 - 0.26 11.2 8.7 5.2 7.0 0.7 3.0 2 1 0 2 2 2 0 Heat shock factor binding protein 1 Phage_connect_1 PF05135.13 EON99147.1 - 0.056 14.0 0.1 20 5.8 0.0 2.6 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein SesA PF17107.5 EON99147.1 - 0.095 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases SRP-alpha_N PF04086.13 EON99147.1 - 1 9.3 14.0 2 8.3 14.0 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal AF-4 PF05110.13 EON99147.1 - 1.9 6.5 12.2 2.5 6.0 12.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF3915 PF13054.6 EON99147.1 - 9.6 6.2 12.2 0.21 11.6 4.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Zip PF02535.22 EON99148.1 - 1.8e-64 218.1 5.9 2.2e-64 217.8 5.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter MAP65_ASE1 PF03999.12 EON99149.1 - 1.1e-72 245.7 1.8 1.1e-72 245.7 1.8 1.4 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) NUDIX PF00293.28 EON99150.1 - 7.2e-17 61.7 0.1 9.6e-17 61.3 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EON99150.1 - 0.00014 21.8 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain eIF-3c_N PF05470.12 EON99151.1 - 5.7e-176 586.3 24.1 1.6e-141 472.6 3.6 3.2 1 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EON99151.1 - 4.9e-13 49.5 0.0 2.4e-12 47.3 0.0 2.3 1 0 0 1 1 1 1 PCI domain DUF1617 PF07761.12 EON99151.1 - 0.036 14.2 2.1 0.061 13.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1617) DASH_Ask1 PF08655.10 EON99151.1 - 0.14 12.1 0.2 0.34 10.8 0.2 1.7 1 0 0 1 1 1 0 DASH complex subunit Ask1 ATP13 PF12921.7 EON99152.1 - 1.6e-22 79.5 0.0 4.7e-22 78.0 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ATPase expression Wzy_C_2 PF11846.8 EON99152.1 - 0.027 14.4 2.5 3 7.7 0.6 2.8 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal HalX PF08663.10 EON99153.1 - 0.049 14.0 4.8 0.17 12.3 4.8 1.9 1 0 0 1 1 1 0 HalX domain PTCB-BRCT PF12738.7 EON99155.1 - 1.9e-47 159.0 0.4 4.3e-22 77.8 0.0 3.9 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 EON99155.1 - 9.7e-38 128.4 0.1 2e-12 47.3 0.0 4.3 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EON99155.1 - 1.3e-14 54.4 0.1 4.1e-07 30.3 0.0 3.7 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EON99155.1 - 4.9e-07 30.0 2.9 0.0035 17.6 0.1 3.5 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EON99155.1 - 0.0027 17.8 0.3 0.055 13.6 0.2 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain CN_hydrolase PF00795.22 EON99156.1 - 1.2e-24 87.0 0.0 1.3e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FA_desaturase PF00487.24 EON99157.1 - 1.8e-31 109.9 22.4 2.7e-31 109.3 22.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EON99157.1 - 7.4e-07 29.2 0.0 2.2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3716 PF12511.8 EON99158.1 - 2.1e-07 30.9 7.8 3.5e-07 30.2 7.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) HIRAN PF08797.11 EON99158.1 - 0.034 14.1 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 HIRAN domain YPEB PF14620.6 EON99158.1 - 0.5 9.7 3.3 0.87 8.9 3.3 1.3 1 0 0 1 1 1 0 YpeB sporulation OmpH PF03938.14 EON99158.1 - 2.3 8.5 7.2 4.6 7.6 3.8 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Glyco_hydro_28 PF00295.17 EON99159.1 - 1.5e-28 99.8 3.0 2.4e-28 99.2 3.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 EON99159.1 - 0.011 15.6 12.6 0.045 13.6 12.6 2.0 1 1 1 2 2 2 0 Right handed beta helix region Vps16_N PF04841.13 EON99160.1 - 1.8e-85 287.2 0.0 1.9e-55 188.3 0.0 2.1 1 1 1 2 2 2 2 Vps16, N-terminal region Vps16_C PF04840.12 EON99160.1 - 8.4e-78 261.6 0.0 1.3e-77 261.0 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 EON99160.1 - 8.3e-05 22.8 0.0 0.079 13.3 0.0 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_S10 PF00450.22 EON99161.1 - 1.2e-80 272.0 0.1 2.2e-80 271.1 0.1 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Urb2 PF10441.9 EON99162.1 - 2.2e-67 226.9 1.3 4.2e-67 226.1 1.3 1.5 1 0 0 1 1 1 1 Urb2/Npa2 family Fanconi_A_N PF15865.5 EON99162.1 - 0.0051 16.3 0.9 0.0051 16.3 0.9 1.7 2 0 0 2 2 2 1 Fanconi anaemia group A protein N terminus Polyketide_cyc PF03364.20 EON99163.1 - 7.6e-22 77.9 0.0 9.8e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport D123 PF07065.14 EON99164.1 - 1e-102 343.4 0.0 1.3e-102 343.1 0.0 1.0 1 0 0 1 1 1 1 D123 GDA1_CD39 PF01150.17 EON99165.1 - 2.5e-98 329.5 0.0 3e-98 329.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Sas10 PF09368.10 EON99166.1 - 1.2e-29 102.6 6.6 1.2e-29 102.6 6.6 2.9 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EON99166.1 - 7.7e-11 42.5 0.1 2.3e-09 37.7 0.0 3.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family IF4E PF01652.18 EON99167.1 - 6.4e-38 130.1 0.2 8.3e-38 129.7 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CN_hydrolase PF00795.22 EON99168.1 - 4.6e-39 134.3 0.0 6.6e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EON99168.1 - 6.4e-22 77.8 0.0 3.3e-21 75.5 0.0 2.0 1 1 0 1 1 1 1 NAD synthase Vps51 PF08700.11 EON99169.1 - 8.2e-11 41.8 0.0 3.1e-10 40.0 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 HrpB7 PF09486.10 EON99169.1 - 0.016 15.6 6.5 0.16 12.3 0.1 3.0 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF4054 PF13262.6 EON99169.1 - 0.063 13.3 0.1 0.28 11.2 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) TGT PF01702.18 EON99170.1 - 1.2e-58 198.9 0.0 1.5e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase zf-C2H2_4 PF13894.6 EON99171.1 - 0.0063 17.2 2.9 3.5 8.7 1.0 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EON99171.1 - 0.15 12.5 7.7 0.37 11.3 0.1 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type Kinesin PF00225.23 EON99172.1 - 5e-113 377.4 0.0 5e-113 377.4 0.0 1.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EON99172.1 - 7.6e-24 84.3 0.0 2e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding YabA PF06156.13 EON99172.1 - 0.17 12.5 8.4 2.8 8.6 0.2 3.5 2 1 1 3 3 3 0 Initiation control protein YabA PX PF00787.24 EON99172.1 - 0.18 11.8 1.3 19 5.3 0.0 2.7 3 0 0 3 3 3 0 PX domain DUF87 PF01935.17 EON99172.1 - 0.61 10.1 0.0 0.61 10.1 0.0 3.5 3 1 0 3 3 3 0 Helicase HerA, central domain SIKE PF05769.11 EON99172.1 - 2.2 8.2 15.3 0.22 11.4 9.9 2.0 2 1 0 2 2 2 0 SIKE family DUF5094 PF17015.5 EON99172.1 - 4.3 7.4 7.6 0.77 9.8 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) FUSC PF04632.12 EON99172.1 - 6 5.3 6.1 8.2 4.8 6.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TRAPP PF04051.16 EON99173.1 - 3.8e-40 137.0 0.0 5.4e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component G-alpha PF00503.20 EON99174.1 - 3.6e-125 417.8 2.8 4.1e-125 417.6 2.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EON99174.1 - 2.4e-15 56.4 1.4 2.8e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 EON99174.1 - 8.3e-05 22.3 0.0 0.00036 20.3 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 EON99174.1 - 0.0022 17.4 3.2 0.11 11.9 0.0 2.7 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 EON99174.1 - 0.017 14.8 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EON99174.1 - 0.025 14.8 0.2 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 EON99174.1 - 0.04 13.0 0.1 0.074 12.1 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 EON99174.1 - 0.09 12.1 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 EON99174.1 - 0.12 11.9 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EON99174.1 - 0.13 12.3 0.1 8.8 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ras PF00071.22 EON99175.1 - 5.4e-57 191.9 0.1 6.3e-57 191.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EON99175.1 - 8.6e-32 109.9 0.0 1.2e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EON99175.1 - 1.8e-13 50.3 0.0 2.1e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EON99175.1 - 2.8e-08 33.8 0.0 4.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EON99175.1 - 5.2e-07 29.3 0.0 6.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EON99175.1 - 1.7e-05 24.5 0.1 0.00054 19.5 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EON99175.1 - 8e-05 22.6 0.1 0.0037 17.2 0.1 2.3 1 1 2 3 3 3 1 RsgA GTPase SRPRB PF09439.10 EON99175.1 - 0.0019 17.7 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 EON99175.1 - 0.0029 17.6 0.0 0.0053 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 EON99175.1 - 0.0061 16.3 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EON99175.1 - 0.0068 16.2 0.2 0.2 11.4 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EON99175.1 - 0.01 16.1 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EON99175.1 - 0.015 15.7 0.1 0.02 15.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EON99175.1 - 0.018 14.8 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EON99175.1 - 0.019 14.1 0.1 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.18 EON99175.1 - 0.02 14.2 0.1 0.048 12.9 0.0 1.7 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 EON99175.1 - 0.027 14.0 0.1 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 EON99175.1 - 0.049 13.2 0.0 0.094 12.3 0.0 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EON99175.1 - 0.055 13.4 0.2 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EON99175.1 - 0.067 13.6 0.1 0.32 11.4 0.1 2.1 1 1 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 EON99175.1 - 0.094 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 NTPase TniB PF05621.11 EON99175.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 EON99175.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Methyltransf_12 PF08242.12 EON99176.1 - 2.1e-14 54.1 0.0 6.2e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON99176.1 - 3.2e-14 53.4 0.0 6e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON99176.1 - 3.5e-10 40.4 0.0 6.8e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON99176.1 - 1.8e-09 37.7 0.0 2.9e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON99176.1 - 3.2e-07 30.3 0.0 5.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON99176.1 - 8.8e-05 21.9 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 EON99176.1 - 0.0012 19.8 0.0 0.004 18.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EON99176.1 - 0.0028 17.2 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Roc PF08477.13 EON99176.1 - 0.02 15.1 0.9 0.54 10.5 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NNMT_PNMT_TEMT PF01234.17 EON99176.1 - 0.027 13.7 0.0 5 6.2 0.0 2.2 1 1 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_16 PF10294.9 EON99176.1 - 0.041 13.6 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 EON99176.1 - 0.064 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 EON99177.1 - 4e-05 24.3 0.7 0.01 16.7 0.1 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON99177.1 - 0.021 15.1 0.0 3.7 7.9 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Apc13p PF05839.11 EON99178.1 - 2.1e-29 101.5 0.1 2.4e-29 101.4 0.1 1.0 1 0 0 1 1 1 1 Apc13p protein PUL PF08324.11 EON99179.1 - 4.6e-66 222.9 0.0 6.2e-66 222.5 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 EON99179.1 - 1.3e-33 116.0 0.0 2.1e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 EON99179.1 - 1.5e-13 50.6 0.0 2.8e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 EON99179.1 - 1.4e-05 25.0 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 EON99179.1 - 0.00044 20.7 0.3 0.0034 17.8 0.3 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EON99179.1 - 0.0044 17.0 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 EON99179.1 - 0.011 15.7 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 EON99179.1 - 0.2 11.4 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Redoxin Fungal_trans PF04082.18 EON99180.1 - 4e-15 55.5 2.0 6.1e-15 55.0 2.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3716 PF12511.8 EON99181.1 - 2.6e-17 62.6 7.4 4e-17 62.0 7.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Med15 PF09606.10 EON99181.1 - 0.095 11.4 11.9 0.11 11.1 11.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4404 PF14357.6 EON99181.1 - 7 7.4 7.3 46 4.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Ribosomal_L1 PF00687.21 EON99182.1 - 7.4e-46 156.5 0.3 8.3e-46 156.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family ABM PF03992.16 EON99183.1 - 1.4e-09 37.9 0.2 1.8e-09 37.5 0.2 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase NIPSNAP PF07978.13 EON99183.1 - 0.0073 16.5 0.1 0.0086 16.3 0.1 1.2 1 0 0 1 1 1 1 NIPSNAP DUF543 PF04418.12 EON99184.1 - 1.5e-29 101.8 0.0 1.7e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) adh_short PF00106.25 EON99185.1 - 1.9e-26 92.8 0.0 2.6e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON99185.1 - 1.2e-15 57.7 0.0 1.6e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON99185.1 - 7.9e-08 32.4 0.0 1.8e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EON99185.1 - 0.0096 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 EON99185.1 - 0.017 15.1 0.1 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H-binding ATP-synt_ab PF00006.25 EON99185.1 - 0.064 12.9 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Pneumovirus_M2 PF06436.11 EON99185.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) Shikimate_DH PF01488.20 EON99185.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TPR_19 PF14559.6 EON99186.1 - 7.1e-08 32.9 1.0 0.00029 21.3 0.0 3.6 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EON99186.1 - 3.5e-07 29.8 0.1 0.00012 21.9 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EON99186.1 - 1.2e-05 24.9 0.0 0.0027 17.4 0.0 2.7 1 1 1 2 2 2 2 TPR repeat TPR_14 PF13428.6 EON99186.1 - 1.8e-05 25.1 2.7 0.031 15.1 0.1 4.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EON99186.1 - 3.5e-05 23.7 0.0 0.0085 16.2 0.1 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EON99186.1 - 0.00015 21.4 0.0 0.00062 19.5 0.1 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EON99186.1 - 0.00016 21.9 3.0 0.18 12.1 0.1 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EON99186.1 - 0.0011 19.1 0.1 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EON99186.1 - 0.0011 19.2 0.0 0.0056 17.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EON99186.1 - 0.0015 19.1 6.5 0.0054 17.4 0.1 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EON99186.1 - 0.0019 18.7 0.4 5.5 7.8 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EON99186.1 - 0.0025 17.7 0.0 0.03 14.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.6 EON99186.1 - 0.008 15.6 1.8 0.029 13.8 0.1 2.4 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP BTAD PF03704.17 EON99186.1 - 0.013 15.9 0.9 0.084 13.3 0.1 2.6 2 1 0 2 2 2 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 EON99186.1 - 0.024 14.9 0.5 2 8.8 0.0 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat ChAPs PF09295.10 EON99186.1 - 0.053 12.5 0.1 0.062 12.3 0.1 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) ECH_1 PF00378.20 EON99187.1 - 3.2e-25 88.9 0.0 5.2e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON99187.1 - 1.1e-14 54.7 0.0 1.2e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AAA_lid_2 PF17863.1 EON99188.1 - 3.6e-05 23.5 0.1 7.6e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 EON99188.1 - 0.095 12.6 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3955 PF13127.6 EON99189.1 - 1.1e-11 44.4 1.4 1.1e-11 44.4 1.4 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF3955) EamA PF00892.20 EON99189.1 - 1.1e-08 35.3 20.5 1.4e-07 31.7 3.0 3.1 3 0 0 3 3 3 3 EamA-like transporter family PUNUT PF16913.5 EON99189.1 - 3.9e-08 32.9 0.7 3.9e-08 32.9 0.7 1.5 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 EON99189.1 - 1.1e-06 28.4 1.4 1.1e-06 28.4 1.4 1.8 2 0 0 2 2 2 1 Solute carrier family 35 RasGEF PF00617.19 EON99191.1 - 1.1e-59 201.6 0.1 2.2e-59 200.6 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EON99191.1 - 3.7e-29 101.1 0.6 8.3e-29 99.9 0.6 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 EON99191.1 - 2e-15 56.1 0.2 4.5e-15 55.0 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EON99191.1 - 6e-14 51.6 0.1 1.3e-13 50.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EON99191.1 - 1.4e-12 47.1 0.1 3e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 EON99191.1 - 8.6e-05 22.5 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 WW domain LCCL PF03815.19 EON99192.1 - 2.2e-21 75.8 0.2 3.6e-21 75.1 0.2 1.3 1 0 0 1 1 1 1 LCCL domain Peptidase_U4 PF03419.13 EON99192.1 - 0.15 11.3 4.9 0.33 10.2 4.7 1.7 1 1 0 1 1 1 0 Sporulation factor SpoIIGA DUF2304 PF10066.9 EON99192.1 - 4.8 7.4 10.8 5.8 7.2 3.8 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) DUF1771 PF08590.10 EON99193.1 - 2.4e-25 88.7 9.4 4.7e-25 87.8 9.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EON99193.1 - 4.8e-12 46.1 0.4 1.1e-11 44.9 0.4 1.7 1 0 0 1 1 1 1 Smr domain GRP PF07172.11 EON99193.1 - 0.02 15.6 7.7 0.02 15.6 7.7 1.9 2 0 0 2 2 2 0 Glycine rich protein family DUF4407 PF14362.6 EON99193.1 - 0.17 11.2 6.0 0.23 10.8 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Connexin43 PF03508.13 EON99193.1 - 10 5.8 8.0 1.1 8.9 2.2 2.2 2 0 0 2 2 2 0 Gap junction alpha-1 protein (Cx43) Spb1_C PF07780.12 EON99194.1 - 1.9e-85 285.8 24.4 1.9e-85 285.8 24.4 3.4 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 EON99194.1 - 1.1e-55 188.5 0.1 2.5e-55 187.3 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EON99194.1 - 2.5e-51 173.7 8.0 2.5e-51 173.7 8.0 5.2 3 1 2 5 5 5 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 EON99194.1 - 0.026 14.4 0.0 0.099 12.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain E1_FCCH PF16190.5 EON99194.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain Methyltr_RsmB-F PF01189.17 EON99194.1 - 0.16 11.6 1.4 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F NUDIX-like PF09296.11 EON99195.1 - 5.6e-16 59.1 0.0 1.4e-15 57.8 0.0 1.7 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.28 EON99195.1 - 7.7e-15 55.1 0.0 1.5e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 EON99195.1 - 3.8e-06 26.4 1.2 7.1e-06 25.6 1.2 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Adaptin_N PF01602.20 EON99196.1 - 2.1e-82 277.4 0.0 4e-82 276.5 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EON99196.1 - 9.1e-05 22.6 0.0 0.006 16.6 0.0 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EON99196.1 - 0.023 15.1 0.6 0.37 11.2 0.0 3.2 3 0 0 3 3 3 0 HEAT repeats HEAT_EZ PF13513.6 EON99196.1 - 0.049 14.2 2.9 25 5.5 0.0 4.4 5 0 0 5 5 5 0 HEAT-like repeat V-ATPase_H_C PF11698.8 EON99196.1 - 0.06 13.5 0.0 15 5.7 0.0 3.3 3 0 0 3 3 3 0 V-ATPase subunit H cwf21 PF08312.12 EON99197.1 - 3.2e-19 68.8 13.6 3.2e-19 68.8 13.6 1.9 2 0 0 2 2 2 1 cwf21 domain DUF1129 PF06570.11 EON99197.1 - 0.037 13.5 0.2 0.052 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4407 PF14362.6 EON99197.1 - 1.5 8.1 5.0 1.5 8.1 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GvpG PF05120.12 EON99197.1 - 2.9 8.0 13.0 2.8 8.0 2.7 2.3 2 1 0 2 2 2 0 Gas vesicle protein G DUF3577 PF12101.8 EON99198.1 - 0.1 12.4 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) zf-C3HC4_3 PF13920.6 EON99199.1 - 0.58 10.1 8.0 3.1 7.8 3.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) U1snRNP70_N PF12220.8 EON99199.1 - 3.6 8.3 9.6 14 6.4 3.9 2.8 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CDH-cyt PF16010.5 EON99200.1 - 2.3e-52 177.3 0.8 2.6e-52 177.1 0.8 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Mito_carr PF00153.27 EON99201.1 - 1.6e-35 120.9 4.9 6.5e-16 58.0 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pribosyltran PF00156.27 EON99202.1 - 7.7e-07 28.8 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MFS_1 PF07690.16 EON99203.1 - 2.6e-23 82.5 35.7 2.6e-23 82.5 35.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON99203.1 - 2.1e-10 40.1 2.2 2.1e-10 40.1 2.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EON99203.1 - 4.6e-06 25.3 2.1 9.7e-06 24.3 2.1 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2961 PF11175.8 EON99204.1 - 2.5e-72 243.3 3.2 8.7e-67 225.2 1.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2961) E1-E2_ATPase PF00122.20 EON99205.1 - 5.9e-40 136.7 21.1 1.4e-32 112.7 0.1 3.9 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EON99205.1 - 8.5e-27 94.0 0.2 8.5e-27 94.0 0.2 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EON99205.1 - 5e-18 66.2 0.2 1.4e-17 64.6 0.0 1.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EON99205.1 - 9.4e-17 60.5 0.0 2.2e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EON99205.1 - 4.5e-15 55.5 0.0 9.9e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EON99205.1 - 4.5e-06 26.6 1.8 4.9e-05 23.2 0.7 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Thiolase_N PF00108.23 EON99206.1 - 1.2e-67 228.0 1.9 1.5e-67 227.7 1.9 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EON99206.1 - 7.2e-41 138.7 0.3 2e-40 137.3 0.3 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain Siah-Interact_N PF09032.11 EON99207.1 - 0.089 13.1 3.3 0.35 11.2 3.3 2.1 1 0 0 1 1 1 0 Siah interacting protein, N terminal SEP PF08059.13 EON99207.1 - 0.17 12.5 0.6 6.5 7.4 0.0 3.1 2 1 1 3 3 3 0 SEP domain Spore_III_AF PF09581.10 EON99207.1 - 0.39 10.7 4.0 0.78 9.7 4.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) PAS_7 PF12860.7 EON99207.1 - 0.78 9.9 4.0 0.34 11.1 0.5 2.2 2 0 0 2 2 2 0 PAS fold DUF2458 PF10454.9 EON99208.1 - 0.01 15.5 1.1 0.018 14.7 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Abhydrolase_1 PF00561.20 EON99209.1 - 3e-16 59.9 0.0 3.3e-14 53.2 0.0 2.8 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON99209.1 - 1.2e-09 39.1 0.2 1.6e-09 38.7 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON99209.1 - 0.0018 17.6 0.0 0.013 14.8 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_M48 PF01435.18 EON99209.1 - 0.17 11.6 0.1 0.38 10.5 0.0 1.5 2 0 0 2 2 2 0 Peptidase family M48 Sugar_tr PF00083.24 EON99210.1 - 5.5e-27 94.7 17.2 6.2e-27 94.6 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON99210.1 - 1.8e-08 33.7 11.1 2e-08 33.6 11.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DPM3 PF08285.11 EON99210.1 - 0.2 11.9 0.2 0.2 11.9 0.2 2.8 2 2 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF2069 PF09842.9 EON99210.1 - 0.2 11.9 0.3 0.2 11.9 0.3 2.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2069) DUF2818 PF10993.8 EON99210.1 - 0.61 10.7 4.6 0.92 10.1 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2818) Dynamin_N PF00350.23 EON99211.1 - 1.2e-10 41.7 0.1 3e-09 37.2 0.0 3.0 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EON99211.1 - 1.6e-05 24.9 0.0 0.22 11.6 0.0 3.3 2 1 0 2 2 2 2 50S ribosome-binding GTPase IIGP PF05049.13 EON99211.1 - 0.018 14.1 0.3 0.085 11.9 0.0 2.3 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 EON99211.1 - 0.041 14.3 1.5 2.1 8.7 0.1 3.2 1 1 1 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EON99211.1 - 0.045 14.3 0.1 0.23 11.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Tubulin PF00091.25 EON99211.1 - 0.046 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain AAA_22 PF13401.6 EON99211.1 - 0.054 13.8 0.1 9.1 6.6 0.0 3.9 3 1 1 4 4 4 0 AAA domain SAT PF16073.5 EON99211.1 - 0.098 12.4 0.2 0.21 11.3 0.2 1.5 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis RsgA_GTPase PF03193.16 EON99211.1 - 0.14 12.1 0.0 0.49 10.3 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase PRK PF00485.18 EON99211.1 - 0.15 11.7 0.0 0.15 11.7 0.0 2.1 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Importin_rep_4 PF18808.1 EON99211.1 - 2.8 8.3 6.6 8.8 6.7 0.8 3.1 3 0 0 3 3 2 0 Importin repeat TcdB_N PF12918.7 EON99211.1 - 2.9 8.3 6.5 31 5.0 0.1 3.5 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain RecG_N PF17190.4 EON99211.1 - 7.9 7.3 7.4 6.3 7.6 0.8 3.3 3 0 0 3 3 2 0 RecG N-terminal helical domain Glyco_transf_90 PF05686.12 EON99212.1 - 1.9e-09 36.9 0.0 1e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 90 ImpA_N PF06812.12 EON99212.1 - 0.017 15.3 0.1 0.034 14.2 0.1 1.5 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system Sugar_tr PF00083.24 EON99213.1 - 1.2e-78 265.0 19.4 1.5e-78 264.7 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON99213.1 - 1.6e-16 60.2 22.5 1.6e-16 60.2 22.5 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2456 PF10445.9 EON99213.1 - 0.95 9.6 7.4 6.4 6.9 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) MFS_1 PF07690.16 EON99215.1 - 6e-30 104.4 28.0 7.7e-30 104.0 28.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON99215.1 - 2.9e-12 46.2 12.3 4.6e-12 45.5 9.3 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EON99215.1 - 1.5e-05 23.7 4.5 2.1e-05 23.2 4.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EON99215.1 - 0.031 12.6 1.5 0.059 11.6 1.5 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Myco_arth_vir_N PF09610.10 EON99215.1 - 0.033 14.3 0.2 0.1 12.7 0.2 1.8 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) KR PF08659.10 EON99217.1 - 1e-56 191.7 2.4 1.2e-56 191.5 0.8 2.0 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EON99217.1 - 4e-54 184.3 0.0 6.6e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EON99217.1 - 6.3e-48 163.5 0.0 1.1e-47 162.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EON99217.1 - 2.1e-33 114.8 0.0 1.3e-32 112.3 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EON99217.1 - 9.4e-20 71.1 0.0 2.7e-19 69.7 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EON99217.1 - 1.7e-16 61.5 0.0 9.3e-16 59.1 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EON99217.1 - 1e-11 44.6 0.7 3.1e-11 43.1 0.7 1.8 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 EON99217.1 - 2.8e-11 43.5 0.0 1.4e-10 41.3 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EON99217.1 - 2.6e-06 27.7 1.0 7.9e-06 26.1 0.3 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.12 EON99217.1 - 4.7e-05 23.2 1.3 0.00014 21.7 1.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain C166 PF17615.2 EON99218.1 - 1.4e-06 28.5 6.1 2e-06 28.1 6.1 1.1 1 0 0 1 1 1 1 Family of unknown function DUF4611 PF15387.6 EON99218.1 - 0.2 11.9 0.0 0.44 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AAA PF00004.29 EON99219.1 - 1.2e-11 45.2 0.0 2.4e-11 44.2 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EON99219.1 - 0.00081 19.7 0.0 0.0031 17.8 0.0 1.9 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EON99219.1 - 0.0017 18.1 0.1 0.01 15.6 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.12 EON99219.1 - 0.0031 17.3 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EON99219.1 - 0.0061 17.0 0.4 0.024 15.0 0.4 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 EON99219.1 - 0.0076 16.7 0.1 0.029 14.8 0.0 2.0 3 0 0 3 3 3 1 AAA domain Spore_GerQ PF09671.10 EON99219.1 - 0.009 16.0 0.1 0.24 11.5 0.0 2.5 2 1 0 2 2 2 1 Spore coat protein (Spore_GerQ) AAA_33 PF13671.6 EON99219.1 - 0.015 15.5 0.0 0.021 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EON99219.1 - 0.016 15.7 0.0 0.036 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EON99219.1 - 0.021 14.8 0.0 0.063 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EON99219.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EON99219.1 - 0.082 12.2 0.0 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 EON99219.1 - 0.18 11.1 0.0 0.38 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF948 PF06103.11 EON99220.1 - 0.001 19.2 0.9 0.2 11.9 0.1 2.2 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF948) Phage_holin_7_1 PF16081.5 EON99220.1 - 1 9.5 8.3 0.19 11.9 3.2 2.1 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DAHP_synth_1 PF00793.20 EON99221.1 - 6.4e-106 353.2 0.1 7.8e-106 352.9 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family AbiEi_1 PF09407.10 EON99221.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 AbiEi antitoxin C-terminal domain Glyco_hydro_10 PF00331.20 EON99222.1 - 1.3e-63 215.1 0.0 1.6e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Erf4 PF10256.9 EON99223.1 - 0.00088 19.4 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4646 PF15496.6 EON99223.1 - 0.0085 16.7 0.1 0.064 13.9 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4646) Sugar_tr PF00083.24 EON99224.1 - 4.1e-72 243.5 10.5 5.1e-72 243.2 10.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter PAP_assoc PF03828.19 EON99225.1 - 3.6e-14 52.7 0.0 6.2e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EON99225.1 - 1.9e-08 34.5 0.0 4.3e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase domain p450 PF00067.22 EON99227.1 - 2.8e-35 122.0 0.0 4.7e-25 88.3 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 KNOX2 PF03791.13 EON99227.1 - 0.013 14.9 0.0 0.036 13.6 0.0 1.7 1 0 0 1 1 1 0 KNOX2 domain FAD_binding_2 PF00890.24 EON99228.1 - 8.7e-27 94.2 5.5 2.1e-18 66.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 EON99228.1 - 5.2e-09 36.0 1.0 4.8e-07 29.5 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.24 EON99228.1 - 2.6e-07 30.5 2.4 6.6e-07 29.2 2.4 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON99228.1 - 0.00023 20.5 0.1 0.0045 16.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON99228.1 - 0.00044 19.1 1.3 0.00055 18.8 0.4 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EON99228.1 - 0.0013 18.0 0.1 0.0021 17.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EON99228.1 - 0.0081 16.7 1.5 3.5 8.3 0.2 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 EON99228.1 - 0.0095 15.3 0.1 0.15 11.4 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EON99228.1 - 0.013 15.7 0.8 0.031 14.5 0.8 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EON99228.1 - 0.013 14.6 1.1 0.013 14.6 1.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EON99228.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EON99228.1 - 0.093 11.8 0.2 0.16 10.9 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Asp PF00026.23 EON99230.1 - 7.6e-52 176.7 0.3 9.9e-52 176.3 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EON99230.1 - 2.2e-09 37.8 0.1 7.1e-09 36.1 0.1 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal BTB PF00651.31 EON99231.1 - 2.5e-05 24.4 0.0 8e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Peptidase_M20 PF01546.28 EON99232.1 - 4.3e-32 111.5 0.0 7.2e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EON99232.1 - 2e-07 30.9 0.0 3.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EON99232.1 - 0.0021 17.8 0.0 0.0065 16.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 Acetyltransf_1 PF00583.25 EON99233.1 - 3.9e-12 46.4 0.0 5.8e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EON99233.1 - 3.6e-08 33.4 0.0 5.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EON99233.1 - 1.5e-06 28.5 0.0 2.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EON99233.1 - 0.00053 19.9 0.0 0.0015 18.5 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Pex24p PF06398.11 EON99234.1 - 1.4e-87 294.1 0.0 1.9e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF4449 PF14613.6 EON99236.1 - 0.00025 21.2 4.3 0.00061 19.9 0.0 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF4449) DUF1828 PF08861.10 EON99236.1 - 0.013 15.8 0.0 0.051 13.9 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function DUF1828 YkuI_C PF10388.9 EON99236.1 - 0.17 11.7 2.0 13 5.6 0.1 3.3 2 1 1 3 3 3 0 EAL-domain associated signalling protein domain LIP PF03583.14 EON99237.1 - 5.4e-09 35.8 0.3 0.00016 21.1 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_6 PF12697.7 EON99237.1 - 8.1e-08 33.1 1.5 1.2e-07 32.6 1.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON99237.1 - 1.5e-07 31.0 0.1 1.8e-05 24.1 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EON99237.1 - 0.00016 21.2 0.0 0.074 12.5 0.0 2.2 1 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EON99237.1 - 0.00044 20.0 0.0 0.061 13.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Palm_thioest PF02089.15 EON99237.1 - 0.0094 15.8 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF3089 PF11288.8 EON99237.1 - 0.018 14.6 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_3 PF07859.13 EON99237.1 - 0.029 14.2 0.2 0.068 13.0 0.2 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EON99237.1 - 0.07 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 EON99237.1 - 0.099 12.4 0.0 0.79 9.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EON99237.1 - 0.16 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Actin PF00022.19 EON99238.1 - 2.4e-71 240.5 0.0 2.5e-70 237.2 0.0 1.9 1 1 0 1 1 1 1 Actin UQ_con PF00179.26 EON99240.1 - 1.5e-20 73.3 0.1 2e-20 72.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EON99240.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B ABC2_membrane PF01061.24 EON99243.1 - 2.4e-91 304.8 62.2 2.4e-49 167.6 21.4 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EON99243.1 - 3.9e-35 121.4 0.0 6.8e-17 62.3 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 EON99243.1 - 8e-35 118.6 7.7 5.4e-31 106.4 0.0 3.5 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EON99243.1 - 5e-17 62.3 0.0 5e-17 62.3 0.0 2.5 3 1 0 3 3 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EON99243.1 - 2.1e-06 28.2 0.1 0.0012 19.3 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EON99243.1 - 4.2e-06 26.5 0.0 0.00013 21.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EON99243.1 - 1.5e-05 25.1 0.0 0.17 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EON99243.1 - 4.4e-05 23.5 0.1 0.0046 16.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 EON99243.1 - 9.7e-05 22.3 0.0 0.76 9.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EON99243.1 - 0.00025 21.6 0.0 0.041 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EON99243.1 - 0.00031 20.4 0.8 0.038 13.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EON99243.1 - 0.0028 17.9 0.1 0.52 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EON99243.1 - 0.004 17.6 0.0 0.62 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EON99243.1 - 0.0063 16.0 0.0 1.8 7.9 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 EON99243.1 - 0.011 15.3 0.7 0.19 11.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EON99243.1 - 0.011 15.6 0.3 1.4 8.8 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 EON99243.1 - 0.012 15.3 0.1 1.1 8.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EON99243.1 - 0.054 13.9 0.0 11 6.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EON99243.1 - 0.065 13.7 0.3 0.24 11.9 0.1 2.0 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 EON99243.1 - 0.16 11.7 0.3 16 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zip PF02535.22 EON99243.1 - 3 7.0 8.3 8.9 5.4 7.9 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter SelP_N PF04592.14 EON99243.1 - 7.6 5.9 17.4 14 5.0 17.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region tRNA-synt_His PF13393.6 EON99244.1 - 2.4e-37 128.9 0.0 2.9e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2 PF00152.20 EON99244.1 - 0.00087 18.5 0.0 0.0051 15.9 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) HGTP_anticodon PF03129.20 EON99244.1 - 0.0023 18.0 0.0 0.0046 17.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain SF-assemblin PF06705.11 EON99244.1 - 0.045 13.1 0.1 0.071 12.4 0.1 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin adh_short PF00106.25 EON99245.1 - 7.8e-13 48.3 0.1 8.4e-13 48.2 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON99245.1 - 2.6e-07 30.5 0.2 2.8e-07 30.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EON99245.1 - 3.8e-05 23.7 0.1 4.3e-05 23.5 0.1 1.0 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EON99245.1 - 5.3e-05 23.2 0.0 5.7e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON99245.1 - 0.0032 17.0 0.0 0.0033 16.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EON99245.1 - 0.04 13.5 0.1 0.052 13.1 0.1 1.1 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 EON99245.1 - 0.046 13.1 0.0 0.052 13.0 0.0 1.0 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short_C2 PF13561.6 EON99246.1 - 6.1e-56 189.6 1.5 6.8e-56 189.4 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON99246.1 - 2.5e-45 154.3 0.0 3.4e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON99246.1 - 1.8e-10 41.0 0.1 2.5e-10 40.6 0.1 1.4 1 1 0 1 1 1 1 KR domain SPESP1 PF15754.5 EON99247.1 - 0.24 10.5 0.2 0.31 10.2 0.2 1.1 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 GFA PF04828.14 EON99248.1 - 0.00059 20.1 0.3 0.37 11.2 0.0 3.2 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme UFD1 PF03152.14 EON99249.1 - 7.5e-28 97.2 0.0 2.7e-14 53.0 0.0 4.0 4 0 0 4 4 4 3 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 EON99249.1 - 2e-06 27.9 0.0 6.1e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-HYPF PF07503.12 EON99249.1 - 0.051 13.4 0.4 0.051 13.4 0.4 3.2 4 0 0 4 4 4 0 HypF finger zf-C2H2 PF00096.26 EON99249.1 - 0.29 11.7 14.7 0.87 10.2 0.2 5.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type Alkyl_sulf_dimr PF14863.6 EON99250.1 - 3.7e-48 163.5 0.3 7e-48 162.6 0.3 1.5 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 EON99250.1 - 9.3e-23 81.3 1.1 1.6e-22 80.5 1.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 EON99250.1 - 1.1e-11 45.1 0.0 2.2e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.7 EON99250.1 - 6.9e-06 25.7 0.1 1.6e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DPM3 PF08285.11 EON99252.1 - 7.6e-34 115.8 0.1 8.5e-34 115.6 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) WSC PF01822.19 EON99253.1 - 3.6e-53 177.7 52.8 8.6e-20 70.7 12.0 3.6 3 0 0 3 3 3 3 WSC domain ASH PF15780.5 EON99253.1 - 3.6e-05 23.9 9.6 0.015 15.4 0.2 4.1 3 1 1 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PQQ_2 PF13360.6 EON99253.1 - 0.0045 16.6 1.8 0.89 9.1 0.0 3.0 3 0 0 3 3 3 2 PQQ-like domain DUF1573 PF07610.11 EON99253.1 - 0.013 15.6 6.2 0.14 12.2 0.5 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1573) PQQ_3 PF13570.6 EON99253.1 - 0.053 14.0 21.0 0.13 12.8 0.0 5.9 7 0 0 7 7 7 0 PQQ-like domain PQQ PF01011.21 EON99253.1 - 0.16 12.0 2.7 1.7 8.7 0.1 3.6 3 0 0 3 3 3 0 PQQ enzyme repeat NPCBM_assoc PF10633.9 EON99253.1 - 0.2 11.9 3.0 0.21 11.8 0.4 2.5 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Sugar_tr PF00083.24 EON99254.1 - 3.1e-43 148.3 6.3 3e-31 108.8 1.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EON99254.1 - 2.6e-12 46.3 14.1 8e-12 44.7 14.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 EON99255.1 - 4.7e-22 78.3 0.0 8.5e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dioxygenase_C PF00775.21 EON99256.1 - 4.6e-10 39.2 0.2 8.8e-10 38.3 0.2 1.5 1 1 0 1 1 1 1 Dioxygenase SpaA PF17802.1 EON99256.1 - 0.0017 18.7 1.0 0.0078 16.5 0.0 2.5 3 0 0 3 3 3 1 Prealbumin-like fold domain bMG3 PF11974.8 EON99256.1 - 0.045 13.8 0.8 3.2 7.8 0.0 3.2 2 1 1 4 4 4 0 Bacterial alpha-2-macroglobulin MG3 domain Methyltransf_25 PF13649.6 EON99258.1 - 6.2e-17 62.1 0.0 2.5e-16 60.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON99258.1 - 5.3e-15 55.8 0.0 1.4e-14 54.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON99258.1 - 2.1e-11 44.0 0.0 2.9e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON99258.1 - 4.5e-08 33.7 0.0 9.4e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON99258.1 - 5.3e-07 29.5 0.0 6.8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EON99258.1 - 1.8e-05 24.4 0.0 2.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 EON99258.1 - 0.00029 20.3 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EON99258.1 - 0.00058 19.4 0.0 0.0011 18.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 EON99258.1 - 0.0025 16.9 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.12 EON99258.1 - 0.0042 16.6 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase TehB PF03848.14 EON99258.1 - 0.013 15.0 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Fibrillarin PF01269.17 EON99258.1 - 0.036 13.2 0.0 5.9 5.9 0.0 2.1 2 0 0 2 2 2 0 Fibrillarin CheR PF01739.18 EON99258.1 - 0.085 12.3 0.0 0.25 10.8 0.0 1.8 2 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain Pkinase PF00069.25 EON99259.1 - 8.7e-11 41.7 0.0 1.4e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON99259.1 - 7.2e-06 25.5 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EON99259.1 - 6.8e-05 22.3 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EON99259.1 - 0.0012 18.8 0.1 0.0022 18.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EON99259.1 - 0.006 16.1 0.0 0.0096 15.5 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 EON99259.1 - 0.024 14.2 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EON99259.1 - 0.086 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Vint PF14623.6 EON99260.1 - 9.1e-66 220.8 0.0 1.3e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 EON99260.1 - 1.9e-29 101.6 0.0 3.4e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 EON99260.1 - 3.7e-15 56.6 0.0 8.3e-15 55.5 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EON99260.1 - 4.2e-12 46.7 0.0 9.1e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EON99260.1 - 3.7e-09 36.7 0.0 1e-07 32.0 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain Hint PF01079.20 EON99260.1 - 0.047 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Hint module RXT2_N PF08595.11 EON99261.1 - 7.9 6.5 13.8 2.7 8.0 2.3 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal 2-Hacid_dh_C PF02826.19 EON99262.1 - 8.4e-32 110.0 0.0 2.6e-31 108.4 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EON99262.1 - 0.00053 19.7 0.0 0.00061 19.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain LPD37 PF18853.1 EON99262.1 - 0.015 14.9 0.0 0.034 13.7 0.0 1.5 2 0 0 2 2 2 0 Large polyvalent protein associated domain 37 Bac_surface_Ag PF01103.23 EON99263.1 - 6.6e-41 140.9 0.2 8.3e-41 140.5 0.2 1.1 1 0 0 1 1 1 1 Surface antigen Aldo_ket_red PF00248.21 EON99265.1 - 7.4e-45 153.4 0.0 8e-44 150.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Septum_form PF13845.6 EON99265.1 - 0.098 12.2 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 Septum formation Alpha-L-AF_C PF06964.12 EON99266.1 - 6.6e-22 78.4 0.0 1.2e-21 77.6 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Ntox27 PF15531.6 EON99266.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial toxin 27 COX14 PF14880.6 EON99267.1 - 3.6e-19 68.4 0.4 3.6e-19 68.4 0.4 1.7 2 0 0 2 2 2 1 Cytochrome oxidase c assembly EF1_GNE PF00736.19 EON99268.1 - 7.3e-11 42.1 0.0 9.1e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain UBA_3 PF09288.10 EON99268.1 - 0.1 12.4 0.2 16 5.4 0.0 2.2 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain ABC_tran PF00005.27 EON99270.1 - 5.5e-05 23.7 0.1 9.2e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EON99270.1 - 0.0015 18.8 0.0 0.0023 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EON99270.1 - 0.0067 16.2 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EON99270.1 - 0.01 15.7 0.0 0.026 14.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EON99270.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 EON99270.1 - 0.015 15.0 0.1 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EON99270.1 - 0.025 14.9 0.1 0.037 14.4 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EON99270.1 - 0.037 14.6 0.1 0.064 13.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EON99270.1 - 0.039 13.5 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EON99270.1 - 0.068 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EON99270.1 - 0.087 13.1 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EON99270.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EON99270.1 - 0.15 12.6 0.2 0.26 11.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EON99270.1 - 0.16 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 EON99270.1 - 0.16 11.6 0.7 0.2 11.3 0.7 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region Ribosomal_L13e PF01294.18 EON99271.1 - 8.4e-76 253.8 3.3 1.1e-75 253.4 3.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e DUF3006 PF11213.8 EON99271.1 - 0.13 12.6 0.1 0.13 12.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) FMO-like PF00743.19 EON99272.1 - 2.2e-53 181.5 0.0 5.5e-53 180.2 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EON99272.1 - 1.8e-09 37.7 0.0 6.4e-09 35.9 0.0 2.0 2 1 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EON99272.1 - 3e-09 36.6 0.0 2.7e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON99272.1 - 2.9e-08 33.3 0.0 3.4e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EON99272.1 - 9.7e-07 28.7 0.1 0.018 14.6 0.0 3.3 3 1 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 EON99272.1 - 1.1e-06 28.1 0.1 0.12 11.5 0.0 3.9 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EON99272.1 - 9.8e-06 25.6 0.6 0.00086 19.3 0.0 3.5 3 1 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EON99272.1 - 2.1e-05 23.9 0.0 0.00045 19.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EON99272.1 - 0.00016 22.2 0.0 0.00048 20.6 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON99272.1 - 0.0006 18.6 0.0 0.0015 17.3 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EON99272.1 - 0.0015 17.8 0.0 0.0031 16.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 EON99272.1 - 0.0025 17.2 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 EON99272.1 - 0.0089 16.1 0.0 0.85 9.7 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 EON99272.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 EON99272.1 - 0.047 14.1 0.0 6 7.4 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.12 EON99272.1 - 0.063 12.9 0.1 0.83 9.2 0.0 2.4 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 EON99272.1 - 0.069 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EON99272.1 - 0.082 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EON99272.1 - 0.17 11.2 0.0 0.38 10.0 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 EON99272.1 - 0.19 11.7 0.0 0.52 10.3 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Peptidase_A4 PF01828.17 EON99273.1 - 4.1e-24 85.2 0.0 4.8e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase A4 family Acetyltransf_1 PF00583.25 EON99274.1 - 4e-06 27.0 0.0 4.6e-05 23.6 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON99274.1 - 4.6e-06 27.0 0.2 2.7e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EON99274.1 - 0.00057 19.8 0.0 0.0016 18.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EON99274.1 - 0.012 15.5 0.0 0.033 14.1 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 EON99274.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Ribosomal_L50 PF10501.9 EON99275.1 - 1.7e-19 69.9 0.2 3.3e-19 69.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal subunit 39S SAP PF02037.27 EON99275.1 - 0.096 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 SAP domain FMN_red PF03358.15 EON99276.1 - 1.4e-21 76.9 0.0 2.1e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EON99276.1 - 0.0036 17.0 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold bZIP_1 PF00170.21 EON99277.1 - 0.00054 20.0 7.3 0.001 19.1 7.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EON99277.1 - 0.0053 16.8 6.9 0.0093 16.0 6.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DUF4638 PF15472.6 EON99277.1 - 0.15 11.7 3.6 0.22 11.2 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Ndc1_Nup PF09531.10 EON99277.1 - 0.47 9.1 5.6 0.45 9.1 5.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PIEZO PF15917.5 EON99277.1 - 1.6 8.1 5.4 2.2 7.7 5.4 1.1 1 0 0 1 1 1 0 Piezo SPATA3 PF15662.5 EON99277.1 - 5 7.7 12.8 0.95 10.1 9.2 1.5 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family MCM_bind PF09739.9 EON99277.1 - 9.5 4.5 8.5 12 4.1 8.5 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor A_deaminase PF00962.22 EON99278.1 - 3.5e-22 79.2 0.0 3.7e-19 69.2 0.0 2.3 2 0 0 2 2 2 2 Adenosine/AMP deaminase UbiA PF01040.18 EON99279.1 - 0.026 13.8 0.7 0.026 13.8 0.7 2.2 2 0 0 2 2 2 0 UbiA prenyltransferase family DUF2892 PF11127.8 EON99279.1 - 1 9.4 12.0 1.7 8.7 2.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2892) DUF4491 PF14898.6 EON99279.1 - 3 8.3 5.8 2.8 8.4 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) CIA30 PF08547.12 EON99280.1 - 4.1e-36 124.4 0.0 4.7e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Sulfotransfer_4 PF17784.1 EON99281.1 - 2.5e-28 99.4 0.0 3e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EON99281.1 - 9.4e-05 22.9 0.0 9.4e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 Sulfotransferase family Peptidase_M48 PF01435.18 EON99282.1 - 3e-39 134.8 0.0 4e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 SpecificRecomb PF10136.9 EON99282.1 - 0.012 14.0 0.1 0.021 13.2 0.1 1.3 1 0 0 1 1 1 0 Site-specific recombinase Rho_N PF07498.12 EON99283.1 - 0.047 13.6 0.3 0.08 12.9 0.3 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain PRA1 PF03208.19 EON99283.1 - 0.09 12.4 2.8 0.063 12.9 1.0 1.6 2 0 0 2 2 2 0 PRA1 family protein BASP1 PF05466.12 EON99283.1 - 0.48 10.4 5.0 0.67 9.9 5.0 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) DUF3405 PF11885.8 EON99284.1 - 1.5e-215 716.7 2.5 1.5e-215 716.7 2.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) DnaJ PF00226.31 EON99285.1 - 9.8e-15 54.4 0.1 1.5e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF4118 PF13493.6 EON99285.1 - 0.12 12.2 2.4 0.2 11.4 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) Ni_hydr_CYTB PF01292.20 EON99286.1 - 0.017 14.7 4.9 0.062 12.9 4.9 2.0 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF5527 PF17665.1 EON99286.1 - 0.034 13.7 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5527) CcmF_C PF16327.5 EON99286.1 - 0.04 13.2 3.9 0.064 12.5 3.9 1.3 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal DUF350 PF03994.14 EON99286.1 - 0.04 14.1 9.8 0.13 12.4 6.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) SH3_5 PF08460.10 EON99286.1 - 0.11 12.6 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain Kelch_4 PF13418.6 EON99287.1 - 2.3e-20 72.3 15.9 5.1e-07 29.6 0.0 7.4 7 1 1 8 8 8 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EON99287.1 - 5.7e-16 58.4 15.0 0.0004 20.6 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EON99287.1 - 3.7e-14 52.4 3.5 3.8e-05 23.8 0.0 5.6 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 EON99287.1 - 7e-14 51.4 2.6 9.2e-05 22.3 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 EON99287.1 - 1.1e-12 47.4 1.2 1.1e-05 24.9 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 EON99287.1 - 7.3e-09 35.3 3.3 1.8e-05 24.5 0.5 4.8 4 1 0 4 4 4 1 Kelch motif TPR_12 PF13424.6 EON99288.1 - 3.7e-09 36.7 1.1 0.00059 20.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EON99288.1 - 0.0001 22.1 10.2 0.0024 17.8 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EON99288.1 - 0.00021 21.1 0.7 3.8 7.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EON99288.1 - 0.0079 16.9 3.6 0.84 10.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EON99288.1 - 0.029 15.0 0.5 6.7 7.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EON99288.1 - 0.11 12.8 5.2 0.8 10.1 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EON99288.1 - 0.13 12.1 7.1 1.3 9.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EON99288.1 - 0.69 9.9 0.1 0.69 9.9 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 EON99288.1 - 3.3 7.4 7.1 0.57 9.9 0.3 2.9 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 EON99288.1 - 4.8 6.9 6.6 11 5.8 0.2 3.6 4 0 0 4 4 4 0 TPR repeat AMP-binding PF00501.28 EON99289.1 - 1.6e-42 145.6 0.0 2.1e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON99289.1 - 2.4e-12 47.7 0.4 6.3e-12 46.3 0.4 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Trehalase PF01204.18 EON99291.1 - 5.3e-196 652.4 0.0 6.5e-196 652.1 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EON99291.1 - 4e-17 61.6 0.6 6.6e-17 60.9 0.6 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Egh16-like PF11327.8 EON99292.1 - 9.1e-70 234.8 3.3 1.4e-69 234.2 3.3 1.3 1 1 0 1 1 1 1 Egh16-like virulence factor Glyco_hydro_61 PF03443.14 EON99293.1 - 9.2e-63 211.9 0.1 1.1e-62 211.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 2Fe-2S_thioredx PF01257.19 EON99294.1 - 2.5e-58 196.1 0.0 3.1e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin NMT1 PF09084.11 EON99294.1 - 0.03 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 NMT1/THI5 like Glyco_trans_2_3 PF13632.6 EON99295.1 - 3.9e-52 177.0 1.6 3.9e-52 177.0 1.6 1.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EON99295.1 - 1.4e-06 28.2 0.0 6.4e-06 26.1 0.0 2.0 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EON99295.1 - 0.00012 21.6 0.0 0.00027 20.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EON99295.1 - 0.0045 16.9 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NAD_binding_10 PF13460.6 EON99297.1 - 1.8e-14 54.0 0.2 3e-14 53.3 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EON99297.1 - 5.9e-12 45.6 0.0 9.7e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EON99297.1 - 6e-05 22.6 0.0 0.00099 18.6 0.0 2.2 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EON99297.1 - 0.00039 20.7 0.0 0.00068 19.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 EON99297.1 - 0.0084 15.3 0.0 0.02 14.1 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein TraI_2 PF07514.11 EON99297.1 - 0.01 14.8 0.0 0.039 12.9 0.0 1.8 2 0 0 2 2 2 0 Putative helicase Peptidase_M57 PF12388.8 EON99297.1 - 0.078 12.6 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Glyco_transf_4 PF13439.6 EON99297.1 - 0.078 13.0 0.0 0.25 11.3 0.0 1.8 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Big_3_5 PF16640.5 EON99297.1 - 0.091 13.0 0.8 4 7.7 0.0 2.8 3 0 0 3 3 2 0 Bacterial Ig-like domain (group 3) Isochorismatase PF00857.20 EON99297.1 - 0.1 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Isochorismatase family POR PF01558.18 EON99297.1 - 0.16 12.0 1.0 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Rft-1 PF04506.13 EON99298.1 - 0.011 14.6 0.3 0.016 14.0 0.3 1.1 1 0 0 1 1 1 0 Rft protein ATG7_N PF16420.5 EON99299.1 - 2.9e-112 375.2 0.0 3.8e-112 374.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EON99299.1 - 1.6e-43 148.9 0.0 2.4e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family DUF3618 PF12277.8 EON99299.1 - 0.088 13.1 0.9 13 6.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Shikimate_DH PF01488.20 EON99299.1 - 0.13 12.3 0.0 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase zf-C2H2_4 PF13894.6 EON99300.1 - 0.00017 22.1 13.1 0.11 13.4 1.4 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EON99300.1 - 0.00083 19.7 13.7 1.5 9.5 0.2 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type CxC7 PF18866.1 EON99300.1 - 0.012 15.7 0.7 0.023 14.8 0.7 1.4 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases zf-met PF12874.7 EON99300.1 - 0.075 13.4 3.9 4.4 7.8 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EON99300.1 - 0.11 12.8 10.7 1 9.7 1.0 3.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 EON99300.1 - 0.19 12.4 4.5 0.15 12.8 0.9 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger DUF629 PF04780.12 EON99300.1 - 1.2 7.6 3.4 1.8 7.0 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Phosphoesterase PF04185.14 EON99301.1 - 6.4e-78 262.4 1.2 6.5e-78 262.4 0.2 1.5 2 0 0 2 2 2 1 Phosphoesterase family Fascin PF06268.13 EON99301.1 - 0.0003 21.0 0.1 0.00076 19.7 0.1 1.7 1 0 0 1 1 1 1 Fascin domain LRR_6 PF13516.6 EON99302.1 - 0.00013 21.8 11.2 0.43 10.8 0.1 6.6 6 0 0 6 6 6 3 Leucine Rich repeat Ribosomal_L5e PF17144.4 EON99303.1 - 2.9e-80 268.0 0.4 5e-80 267.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EON99303.1 - 2.2e-35 121.4 12.5 2.2e-35 121.4 12.5 2.1 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 EON99303.1 - 0.036 14.4 1.7 0.051 14.0 0.1 1.9 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast RRM_1 PF00076.22 EON99304.1 - 5.2e-34 115.9 0.1 6.7e-16 57.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EON99304.1 - 3.5e-12 46.3 0.1 7e-05 22.9 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EON99304.1 - 0.0001 22.2 0.0 0.67 10.0 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EON99304.1 - 0.095 12.8 0.0 6.6 6.8 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif Glyco_hydro_16 PF00722.21 EON99305.1 - 9.4e-06 25.2 0.2 0.0002 20.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 MFS_1 PF07690.16 EON99306.1 - 1.2e-43 149.4 29.3 1.2e-43 149.4 29.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EON99306.1 - 0.064 11.5 3.4 0.085 11.1 1.1 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Cyt-b5 PF00173.28 EON99307.1 - 3.1e-21 75.3 0.4 3.4e-21 75.2 0.4 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 EON99307.1 - 0.079 13.1 0.1 2.4 8.3 0.0 2.0 1 1 1 2 2 2 0 V-ATPase subunit H bZIP_1 PF00170.21 EON99308.1 - 3.2e-07 30.3 7.7 3.2e-07 30.3 7.7 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EON99308.1 - 6.1e-05 23.0 5.6 6.1e-05 23.0 5.6 1.7 2 0 0 2 2 2 1 Basic region leucine zipper SHE3 PF17078.5 EON99308.1 - 0.0039 16.9 0.3 0.0058 16.4 0.3 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 EON99308.1 - 0.032 14.7 8.0 0.032 14.7 8.0 1.5 2 0 0 2 2 2 0 bZIP Maf transcription factor PKcGMP_CC PF16808.5 EON99308.1 - 0.035 14.0 0.5 0.062 13.2 0.5 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase BCL9 PF11502.8 EON99308.1 - 0.049 13.4 0.2 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 B-cell lymphoma 9 protein DUF745 PF05335.13 EON99308.1 - 0.057 13.1 3.5 0.082 12.6 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) MAJIN PF15077.6 EON99308.1 - 0.13 12.0 3.4 0.17 11.7 3.4 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein SHNi-TPR PF10516.9 EON99309.1 - 1.1e-14 53.6 0.1 1.1e-14 53.6 0.1 3.0 3 0 0 3 3 3 1 SHNi-TPR TPR_16 PF13432.6 EON99309.1 - 5e-05 23.9 5.0 0.00018 22.1 0.7 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EON99309.1 - 0.00012 22.3 5.0 0.023 15.0 0.5 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3856 PF12968.7 EON99309.1 - 0.0035 17.4 0.7 0.085 12.9 0.2 2.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_3 PF07720.12 EON99309.1 - 0.0054 16.7 3.8 0.015 15.3 3.8 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EON99309.1 - 0.031 14.8 2.2 0.083 13.4 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EON99309.1 - 0.53 10.5 15.4 0.11 12.7 3.6 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat ICL PF00463.21 EON99310.1 - 1.1e-297 987.7 1.4 1.2e-297 987.6 1.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EON99310.1 - 2.3e-11 43.6 0.1 8.3e-11 41.8 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Forkhead PF00250.18 EON99311.1 - 1.7e-16 60.2 0.0 5e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EON99311.1 - 2.5e-05 24.6 0.1 5.1e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EON99311.1 - 0.057 13.7 0.0 0.2 12.0 0.0 1.9 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain NAD_binding_5 PF07994.12 EON99312.1 - 3.6e-145 483.4 0.1 4.4e-145 483.1 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EON99312.1 - 2.7e-45 153.1 0.6 5.7e-45 152.1 0.6 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF5049 PF16468.5 EON99312.1 - 0.088 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5049) Cyt-b5 PF00173.28 EON99313.1 - 6.7e-13 48.6 0.1 7.5e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain dCMP_cyt_deam_1 PF00383.23 EON99315.1 - 2.4e-27 94.7 1.2 3.5e-27 94.2 1.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EON99315.1 - 6.7e-11 42.1 0.1 1.1e-10 41.4 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 EON99315.1 - 2.4e-05 24.9 0.0 0.00015 22.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 EON99315.1 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase dNK PF01712.19 EON99315.1 - 0.15 11.9 0.0 0.94 9.3 0.0 2.0 2 0 0 2 2 2 0 Deoxynucleoside kinase PhyH PF05721.13 EON99316.1 - 1.3e-62 211.8 0.0 1.6e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EON99316.1 - 0.066 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase PMT PF02366.18 EON99317.1 - 6.9e-83 278.0 14.3 6.9e-83 278.0 14.3 2.0 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EON99317.1 - 2.6e-65 219.8 16.2 7.6e-65 218.2 16.2 1.8 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EON99317.1 - 1.5e-37 129.3 0.5 2.3e-37 128.7 0.5 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.8 EON99317.1 - 0.17 11.7 3.8 1.1 9.1 2.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) RabGAP-TBC PF00566.18 EON99318.1 - 9.8e-48 162.6 0.0 9.8e-48 162.6 0.0 2.9 4 0 0 4 4 4 1 Rab-GTPase-TBC domain Jnk-SapK_ap_N PF09744.9 EON99318.1 - 0.0021 18.3 20.0 0.0021 18.3 20.0 4.0 3 1 1 4 4 4 1 JNK_SAPK-associated protein-1 KASH_CCD PF14662.6 EON99318.1 - 0.0068 16.2 28.1 0.0068 16.2 28.1 2.7 2 1 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH Cnn_1N PF07989.11 EON99318.1 - 0.0074 16.4 11.1 0.0074 16.4 11.1 3.8 2 1 1 3 3 3 2 Centrosomin N-terminal motif 1 Cep57_MT_bd PF06657.13 EON99318.1 - 0.0094 16.4 2.0 0.0094 16.4 2.0 3.9 3 1 1 4 4 4 1 Centrosome microtubule-binding domain of Cep57 HALZ PF02183.18 EON99318.1 - 0.28 11.5 31.7 0.098 12.9 4.5 4.8 5 0 0 5 5 5 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 EON99318.1 - 2.9 8.3 15.9 3.3 8.2 3.2 4.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 EON99318.1 - 8 6.5 13.4 7 6.7 4.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Snf7 PF03357.21 EON99319.1 - 3.3e-34 118.0 12.5 4.1e-34 117.7 12.5 1.1 1 0 0 1 1 1 1 Snf7 Tht1 PF04163.12 EON99319.1 - 0.014 14.2 1.0 0.016 14.0 1.0 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein CK1gamma_C PF12605.8 EON99320.1 - 5.7 8.2 7.1 0.84 10.9 1.4 2.6 3 1 0 3 3 3 0 Casein kinase 1 gamma C terminal CUE PF02845.16 EON99321.1 - 4.3e-13 48.7 0.0 9.5e-13 47.6 0.0 1.6 1 0 0 1 1 1 1 CUE domain LicD PF04991.13 EON99322.1 - 2.3e-23 83.5 2.4 1.7e-16 61.1 0.4 2.2 1 1 1 2 2 2 2 LicD family CENP-Q PF13094.6 EON99323.1 - 1.8e-54 184.5 0.8 1.8e-54 184.5 0.8 3.1 3 1 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Spore_SspJ PF09575.10 EON99324.1 - 0.014 15.7 2.0 0.061 13.7 0.1 2.8 2 1 0 2 2 2 0 Small spore protein J (Spore_SspJ) SICA_alpha PF12887.7 EON99324.1 - 0.014 15.3 0.8 0.02 14.8 0.8 1.3 1 0 0 1 1 1 0 SICA extracellular alpha domain DUF2937 PF11157.8 EON99324.1 - 0.23 11.1 1.1 0.39 10.4 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF5094 PF17015.5 EON99324.1 - 0.25 11.4 2.8 0.5 10.5 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) CRM1_C PF08767.11 EON99325.1 - 4.5e-132 440.1 1.1 4.5e-132 440.1 1.1 3.2 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 EON99325.1 - 3.1e-41 140.9 12.2 5.2e-41 140.2 8.9 3.1 2 1 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EON99325.1 - 3.2e-33 113.2 3.0 9e-33 111.7 3.0 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EON99325.1 - 2.3e-28 98.0 2.4 9.8e-28 96.0 1.2 2.9 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EON99325.1 - 3.3e-19 68.1 2.2 7.6e-19 66.9 2.2 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EON99325.1 - 3.3e-11 42.9 0.4 1.2e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 EON99325.1 - 0.2 12.3 3.9 1 10.0 0.0 4.1 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EON99325.1 - 0.3 11.0 0.0 0.3 11.0 0.0 5.3 6 2 1 7 7 7 0 Domain of unknown function (DUF3385) Ydc2-catalyt PF09159.10 EON99326.1 - 9.7e-27 94.4 0.2 1.1e-26 94.2 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 DUF2582 PF10771.9 EON99326.1 - 0.018 15.2 0.2 0.031 14.4 0.2 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix domain (DUF2582) Aa_trans PF01490.18 EON99327.1 - 1.2e-19 70.3 12.5 1.5e-19 70.0 12.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ribosomal_S6e PF01092.19 EON99329.1 - 4e-60 201.3 0.1 7.6e-60 200.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e WLM PF08325.10 EON99330.1 - 4e-53 180.3 0.1 8.3e-53 179.3 0.0 1.5 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.17 EON99330.1 - 0.0055 16.8 0.9 0.0055 16.8 0.9 2.2 2 0 0 2 2 2 1 Protein of unknown function DUF45 Reprolysin_5 PF13688.6 EON99330.1 - 0.014 15.6 0.1 0.035 14.3 0.1 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12 SelP_N PF04592.14 EON99330.1 - 0.32 10.4 5.8 0.57 9.5 5.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ERCC4 PF02732.15 EON99331.1 - 2.5e-31 109.0 0.0 4.3e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain DUF1484 PF07363.11 EON99331.1 - 0.19 12.7 3.1 0.14 13.2 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) Pga1 PF10333.9 EON99332.1 - 1.1e-05 25.4 0.5 3.2e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 GPI-Mannosyltransferase II co-activator OAD_gamma PF04277.13 EON99333.1 - 0.025 15.1 0.1 0.043 14.4 0.1 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain UPF0560 PF10577.9 EON99333.1 - 0.027 13.0 0.0 0.028 13.0 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SHR3_chaperone PF08229.11 EON99333.1 - 0.028 13.4 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 SieB PF14163.6 EON99333.1 - 0.048 13.2 0.1 0.056 12.9 0.1 1.0 1 0 0 1 1 1 0 Super-infection exclusion protein B UPF0542 PF15086.6 EON99333.1 - 0.051 13.5 0.2 0.062 13.2 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Ninjurin PF04923.12 EON99333.1 - 0.081 12.9 0.0 0.097 12.6 0.0 1.1 1 0 0 1 1 1 0 Ninjurin Nckap1 PF09735.9 EON99333.1 - 0.18 9.7 0.1 0.2 9.6 0.1 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Amidohydro_1 PF01979.20 EON99334.1 - 3.8e-05 23.2 0.0 4.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Pro_isomerase PF00160.21 EON99335.1 - 3.2e-43 147.7 0.0 6e-43 146.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 EON99335.1 - 0.0019 18.7 0.5 0.0019 18.7 0.5 3.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4604) Ribosomal_S8e PF01201.22 EON99337.1 - 5.5e-56 188.5 2.0 6.6e-56 188.3 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e An_peroxidase PF03098.15 EON99337.1 - 0.051 12.1 0.1 0.087 11.4 0.1 1.3 1 0 0 1 1 1 0 Animal haem peroxidase HA2 PF04408.23 EON99338.1 - 9e-16 58.1 0.1 2.1e-15 56.9 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EON99338.1 - 5.2e-15 55.6 0.0 1.4e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EON99338.1 - 5.5e-11 42.8 0.0 1.3e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EON99338.1 - 0.023 14.5 0.1 0.041 13.6 0.1 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase NifU PF01106.17 EON99339.1 - 8.4e-28 96.3 0.1 1.4e-27 95.6 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 EON99339.1 - 2.1e-14 53.3 0.1 1.1e-13 51.0 0.0 2.1 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal Radial_spoke PF04712.12 EON99339.1 - 0.058 12.3 0.3 0.47 9.3 0.1 1.9 2 0 0 2 2 2 0 Radial spokehead-like protein ATP-synt_ab PF00006.25 EON99340.1 - 8.7e-67 224.9 0.0 1.1e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EON99340.1 - 1.6e-05 25.3 0.2 3.7e-05 24.2 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Citrate_bind PF16114.5 EON99341.1 - 4.5e-86 286.9 0.0 6.1e-86 286.4 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 EON99341.1 - 3.5e-07 30.0 0.0 5.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 EON99341.1 - 0.0084 14.3 0.0 0.012 13.7 0.0 1.1 1 0 0 1 1 1 1 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Pyr_redox_2 PF07992.14 EON99342.1 - 5.9e-59 199.7 1.5 9.1e-59 199.1 1.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EON99342.1 - 8e-33 113.0 1.9 3.4e-32 111.0 0.3 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EON99342.1 - 1.3e-19 70.5 3.9 1.6e-18 67.0 0.1 3.2 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON99342.1 - 5.1e-13 48.9 0.3 6.7e-13 48.6 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON99342.1 - 2.2e-07 30.4 0.0 6.9e-07 28.7 0.0 1.7 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EON99342.1 - 2.5e-05 23.2 4.4 0.027 13.2 0.1 3.2 2 1 1 3 3 3 3 HI0933-like protein AlaDh_PNT_C PF01262.21 EON99342.1 - 0.0082 15.5 0.2 3.3 6.9 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EON99342.1 - 0.0093 15.1 0.5 0.1 11.7 0.1 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 EON99342.1 - 0.01 15.1 0.0 0.02 14.1 0.0 1.6 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 EON99342.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EON99342.1 - 0.018 14.9 0.0 0.076 12.9 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EON99342.1 - 0.12 11.7 0.7 0.4 10.0 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EON99342.1 - 0.18 11.0 0.6 13 4.9 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain Steroid_dh PF02544.16 EON99344.1 - 1.3e-22 80.4 0.3 2.2e-22 79.6 0.3 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EON99344.1 - 0.0016 18.0 0.2 0.003 17.1 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF621 PF04789.15 EON99344.1 - 0.06 12.5 1.9 0.084 12.0 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF621) C_Hendra PF16821.5 EON99345.1 - 0.23 11.3 4.0 0.25 11.2 2.8 1.7 1 1 1 2 2 2 0 C protein from hendra and measles viruses zf-ZPR1 PF03367.13 EON99346.1 - 1.4e-114 379.3 0.0 9.6e-59 197.8 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 EON99346.1 - 0.43 10.6 4.0 3.6 7.7 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbons RasGEF PF00617.19 EON99347.1 - 1.9e-42 145.5 0.0 2.5e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain Spindle_Spc25 PF08234.12 EON99348.1 - 6.4e-27 93.6 0.1 1.6e-26 92.3 0.1 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 DUF4407 PF14362.6 EON99348.1 - 0.35 10.2 12.6 0.54 9.6 12.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Bap31_Bap29_C PF18035.1 EON99348.1 - 1.2 9.2 7.3 0.9 9.6 1.6 2.8 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Atg14 PF10186.9 EON99348.1 - 2 7.4 12.3 0.61 9.1 9.4 1.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tudor-knot PF11717.8 EON99349.1 - 2.4e-08 33.7 1.3 4.2e-08 33.0 1.3 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Cytochrom_C PF00034.21 EON99350.1 - 3.9e-11 43.9 0.0 5.3e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EON99350.1 - 6.7e-08 32.7 1.5 2.3e-07 31.0 1.5 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EON99350.1 - 0.0086 15.8 1.3 0.017 14.8 1.3 1.9 1 1 0 1 1 1 1 Cytochrome c-550 domain Cytochrome_P460 PF16694.5 EON99350.1 - 0.14 12.5 0.3 2.4 8.5 0.1 2.2 2 1 0 2 2 2 0 Cytochrome P460 Ras PF00071.22 EON99351.1 - 3e-49 166.7 0.0 5.8e-38 130.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EON99351.1 - 1.2e-27 96.5 0.0 6.4e-18 65.1 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EON99351.1 - 2e-11 43.7 0.0 2.6e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EON99351.1 - 6.9e-06 25.7 0.1 5.8e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EON99351.1 - 3.4e-05 23.3 0.0 0.00017 21.0 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EON99351.1 - 0.00067 19.7 0.0 0.005 16.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EON99351.1 - 0.00089 19.2 0.1 0.79 9.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 EON99351.1 - 0.033 13.7 0.1 4.9 6.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EON99351.1 - 0.11 12.8 0.2 1.2 9.4 0.0 2.4 2 1 1 3 3 3 0 AAA domain PduV-EutP PF10662.9 EON99351.1 - 0.23 11.2 0.1 1.6 8.5 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation COesterase PF00135.28 EON99352.1 - 2.5e-79 267.5 0.0 3.2e-79 267.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EON99352.1 - 0.0029 17.5 1.2 0.021 14.7 1.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold ER_lumen_recept PF00810.18 EON99354.1 - 3.4e-54 183.7 7.6 3.4e-54 183.7 7.6 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EON99354.1 - 0.036 13.8 8.3 1.3 8.8 0.3 3.5 2 1 1 3 3 3 0 PQ loop repeat HSP70 PF00012.20 EON99355.1 - 1e-117 393.8 2.3 7.4e-92 308.5 0.2 2.9 1 1 2 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.13 EON99355.1 - 3e-07 29.6 0.1 4.7e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 MreB/Mbl protein RNase_PH PF01138.21 EON99357.1 - 3.5e-08 34.0 0.0 8.2e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Glyoxal_oxid_N PF07250.11 EON99357.1 - 0.21 10.7 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Citrate_synt PF00285.21 EON99358.1 - 1.3e-20 73.9 0.0 2.1e-17 63.2 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 EON99358.1 - 4.5e-20 72.1 0.3 1.2e-19 70.8 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EON99358.1 - 1.6e-15 57.3 0.1 3.9e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EON99358.1 - 2.9e-06 27.1 0.1 0.00017 21.4 0.0 2.5 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Aminotran_5 PF00266.19 EON99359.1 - 1.2e-27 96.8 0.0 1.5e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EON99359.1 - 5.7e-05 22.4 0.0 9.6e-05 21.7 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II B12-binding PF02310.19 EON99359.1 - 0.003 17.6 0.1 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 B12 binding domain Ribosomal_S5_C PF03719.15 EON99360.1 - 4.4e-23 80.5 0.0 8.4e-23 79.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EON99360.1 - 4.5e-19 68.2 0.9 9.2e-19 67.2 0.9 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain PSP1 PF04468.12 EON99361.1 - 3e-27 94.7 1.6 5.5e-27 93.9 1.6 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF2293 PF10056.9 EON99362.1 - 1.2e-26 92.8 0.0 1.6e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) DUF629 PF04780.12 EON99362.1 - 0.094 11.2 0.0 0.11 11.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF629) WW PF00397.26 EON99363.1 - 1.6e-10 40.9 1.9 2.6e-10 40.2 1.9 1.4 1 0 0 1 1 1 1 WW domain Kinesin PF00225.23 EON99364.1 - 6.3e-59 199.6 2.5 5.5e-58 196.5 0.6 4.4 4 1 1 5 5 5 2 Kinesin motor domain Microtub_bd PF16796.5 EON99364.1 - 0.00076 19.4 0.0 0.0044 17.0 0.0 2.4 1 0 0 1 1 1 1 Microtubule binding DUF1359 PF07097.11 EON99364.1 - 6.2 7.1 14.3 2.7 8.3 1.6 4.6 4 1 1 5 5 5 0 Protein of unknown function (DUF1359) MRG PF05712.13 EON99365.1 - 6.1e-54 182.4 0.0 1e-53 181.6 0.0 1.3 1 0 0 1 1 1 1 MRG MAJIN PF15077.6 EON99365.1 - 2.2 8.0 6.0 2.2 8.0 0.1 2.1 2 0 0 2 2 2 0 Membrane-anchored junction protein AAA PF00004.29 EON99366.1 - 1.6e-82 274.5 0.0 2.7e-46 157.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EON99366.1 - 9.7e-22 76.5 0.0 4.5e-10 39.2 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EON99366.1 - 2.8e-14 53.2 0.0 2.9e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EON99366.1 - 5.4e-13 49.4 1.6 0.0096 16.2 0.0 6.1 3 2 3 6 6 6 2 AAA domain AAA_16 PF13191.6 EON99366.1 - 3.8e-12 46.9 1.8 0.00014 22.3 0.1 4.3 3 2 1 4 4 3 2 AAA ATPase domain AAA_33 PF13671.6 EON99366.1 - 7.9e-12 45.5 0.0 1.9e-06 28.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EON99366.1 - 5.1e-11 42.7 0.9 6.8e-06 26.1 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EON99366.1 - 2e-09 37.8 0.0 0.00024 21.3 0.0 3.7 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 EON99366.1 - 3.6e-09 36.7 0.0 0.00021 21.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 EON99366.1 - 6e-08 32.8 0.0 0.0012 18.8 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_18 PF13238.6 EON99366.1 - 6.1e-08 33.3 0.0 0.0041 17.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EON99366.1 - 2.4e-07 31.1 0.0 0.012 16.0 0.0 2.5 2 0 0 2 2 2 2 RNA helicase TsaE PF02367.17 EON99366.1 - 2.8e-07 30.6 0.0 0.0019 18.2 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin2 PF13189.6 EON99366.1 - 3.6e-07 30.5 0.0 0.00064 19.9 0.0 2.4 2 0 0 2 2 2 2 Cytidylate kinase-like family AAA_28 PF13521.6 EON99366.1 - 5.3e-07 30.0 0.0 0.0029 17.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EON99366.1 - 1.1e-06 28.5 0.2 0.062 13.0 0.1 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 EON99366.1 - 3.7e-06 26.4 0.1 0.092 11.9 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 EON99366.1 - 3.8e-06 26.4 0.2 0.025 13.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EON99366.1 - 5.5e-06 26.9 0.0 0.04 14.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 EON99366.1 - 5.8e-06 26.0 0.1 0.00035 20.3 0.0 2.9 3 0 0 3 3 2 1 P-loop containing region of AAA domain Sigma54_activat PF00158.26 EON99366.1 - 2.6e-05 24.0 0.0 0.057 13.1 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_23 PF13476.6 EON99366.1 - 3.4e-05 24.5 3.4 0.00015 22.3 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_7 PF12775.7 EON99366.1 - 3.9e-05 23.2 0.0 0.49 9.9 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 EON99366.1 - 4.2e-05 23.5 1.1 0.022 14.7 0.1 3.2 3 1 1 4 4 2 1 NACHT domain AAA_3 PF07726.11 EON99366.1 - 0.0001 22.2 0.0 0.21 11.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EON99366.1 - 0.00024 20.9 0.0 0.63 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Cytidylate_kin PF02224.18 EON99366.1 - 0.00025 20.8 0.5 0.083 12.6 0.1 2.6 2 0 0 2 2 2 1 Cytidylate kinase AAA_17 PF13207.6 EON99366.1 - 0.00036 21.0 1.3 1.3 9.4 0.1 3.3 3 1 1 4 4 2 2 AAA domain SKI PF01202.22 EON99366.1 - 0.00036 20.7 0.1 0.9 9.7 0.0 2.8 2 0 0 2 2 2 2 Shikimate kinase Zeta_toxin PF06414.12 EON99366.1 - 0.00039 19.7 0.2 0.28 10.4 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.22 EON99366.1 - 0.00047 19.4 0.0 0.67 9.1 0.0 2.7 3 0 0 3 3 3 2 NB-ARC domain DUF815 PF05673.13 EON99366.1 - 0.00063 19.0 0.0 0.056 12.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 EON99366.1 - 0.002 17.9 0.0 0.89 9.2 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 EON99366.1 - 0.0024 17.5 11.1 0.14 11.7 0.4 4.5 3 1 2 5 5 5 1 AAA domain PhoH PF02562.16 EON99366.1 - 0.0025 17.3 0.2 1 8.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein ATPase_2 PF01637.18 EON99366.1 - 0.0027 17.6 0.0 3.4 7.5 0.0 2.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 EON99366.1 - 0.0028 17.8 0.0 0.59 10.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_11 PF13086.6 EON99366.1 - 0.0032 17.3 0.3 0.57 9.9 0.0 2.6 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.15 EON99366.1 - 0.004 17.1 0.1 2.1 8.2 0.0 2.9 2 1 1 3 3 2 1 NTPase PduV-EutP PF10662.9 EON99366.1 - 0.0048 16.6 0.0 0.46 10.2 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATPase PF06745.13 EON99366.1 - 0.0065 15.8 0.0 0.89 8.9 0.0 2.7 2 0 0 2 2 2 1 KaiC SRPRB PF09439.10 EON99366.1 - 0.01 15.3 0.3 18 4.7 0.0 3.4 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Bac_DnaA PF00308.18 EON99366.1 - 0.011 15.5 0.0 7.3 6.4 0.0 3.1 2 1 0 2 2 2 0 Bacterial dnaA protein Vps4_C PF09336.10 EON99366.1 - 0.013 15.5 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain MCM PF00493.23 EON99366.1 - 0.013 14.6 0.0 0.62 9.1 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain Parvo_NS1 PF01057.17 EON99366.1 - 0.02 14.0 0.1 5.9 5.9 0.1 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 EON99366.1 - 0.047 13.4 0.4 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EON99366.1 - 0.048 14.0 0.1 8.6 6.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EON99366.1 - 0.052 13.4 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase CPT PF07931.12 EON99366.1 - 0.076 12.9 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein T2SSE PF00437.20 EON99366.1 - 0.098 11.7 0.0 9.6 5.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.15 EON99366.1 - 0.11 12.5 0.0 6.9 6.6 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_21 PF13304.6 EON99366.1 - 0.13 12.1 0.0 0.39 10.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system HSF_DNA-bind PF00447.17 EON99367.1 - 2.4e-26 92.1 0.3 5.6e-26 91.0 0.3 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding GLE1 PF07817.13 EON99367.1 - 0.025 13.8 0.3 0.04 13.1 0.3 1.2 1 0 0 1 1 1 0 GLE1-like protein RIH_assoc PF08454.11 EON99367.1 - 0.091 12.6 3.3 0.16 11.8 3.3 1.4 1 0 0 1 1 1 0 RyR and IP3R Homology associated Ets PF00178.22 EON99367.1 - 0.12 12.9 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Ets-domain Spc7 PF08317.11 EON99367.1 - 0.14 11.0 2.5 0.25 10.2 2.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2205 PF10224.9 EON99367.1 - 0.5 10.4 3.5 0.59 10.2 1.2 2.2 2 0 0 2 2 2 0 Short coiled-coil protein WXG100 PF06013.12 EON99367.1 - 0.5 10.6 3.7 4.4 7.6 1.5 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Helicase_C PF00271.31 EON99368.1 - 4.1e-17 62.5 0.0 1.1e-14 54.7 0.0 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EON99368.1 - 1.4e-13 51.3 3.0 1.4e-13 51.3 3.0 1.8 2 0 0 2 2 2 1 RecQ zinc-binding DEAD PF00270.29 EON99368.1 - 0.00046 20.0 0.0 0.0009 19.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SQS_PSY PF00494.19 EON99368.1 - 0.041 13.4 0.3 0.14 11.7 0.1 1.8 2 0 0 2 2 2 0 Squalene/phytoene synthase DUF913 PF06025.12 EON99369.1 - 1.2e-133 445.7 0.0 1.2e-133 445.7 0.0 6.1 6 0 0 6 6 6 2 Domain of Unknown Function (DUF913) HECT PF00632.25 EON99369.1 - 1.1e-95 320.6 0.1 8.8e-95 317.7 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 EON99369.1 - 6.3e-56 190.3 8.9 1.3e-45 156.4 1.9 5.0 4 1 1 5 5 5 2 Domain of Unknown Function (DUF908) UBM PF14377.6 EON99369.1 - 1.8e-25 87.5 20.0 2.5e-08 33.1 4.2 3.9 3 0 0 3 3 3 3 Ubiquitin binding region V-ATPase_H_N PF03224.14 EON99369.1 - 5.2 6.3 7.1 2 7.6 0.2 3.5 4 1 1 5 5 5 0 V-ATPase subunit H ABC_membrane_2 PF06472.15 EON99370.1 - 8.6e-104 346.7 0.6 8.6e-104 346.7 0.6 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EON99370.1 - 1.1e-17 64.9 0.0 2.2e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON99370.1 - 0.00026 20.9 0.0 0.00056 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EON99370.1 - 0.028 14.9 0.1 0.17 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EON99370.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 EON99370.1 - 0.086 12.3 0.0 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EON99370.1 - 0.11 12.9 2.7 0.49 10.7 0.2 2.6 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 EON99370.1 - 0.12 11.8 0.1 0.56 9.6 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 EON99370.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Glyco_hydro_72 PF03198.14 EON99371.1 - 4.7e-116 387.4 0.0 5.7e-116 387.2 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EON99371.1 - 0.037 13.5 0.0 0.2 11.1 0.0 2.0 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Aldose_epim PF01263.20 EON99372.1 - 4.1e-45 154.4 0.1 5.7e-45 153.9 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Zap1_zf2 PF18217.1 EON99372.1 - 3.8 7.6 5.5 9.2 6.4 1.0 2.5 2 0 0 2 2 2 0 Zap1 zinc finger 2 GDPD PF03009.17 EON99373.1 - 2.8e-68 230.5 0.0 5e-68 229.6 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EON99373.1 - 4.3e-29 100.9 0.0 1e-17 64.5 0.1 3.8 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EON99373.1 - 2.2e-28 98.3 0.7 1.1e-09 38.7 0.0 5.3 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EON99373.1 - 8.3e-22 77.0 0.2 1.1e-08 35.2 0.1 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.19 EON99373.1 - 1.4e-21 77.8 8.6 8.2e-12 45.7 0.0 3.7 2 1 2 4 4 4 3 SPX domain Ank PF00023.30 EON99373.1 - 5.9e-17 61.3 2.4 0.00044 20.6 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 EON99373.1 - 2.9e-16 57.9 0.1 0.01 16.3 0.0 7.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 EON99374.1 - 4.9e-33 113.1 11.9 7.7e-11 42.3 0.0 6.5 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EON99374.1 - 1.1e-32 112.4 1.6 1.2e-11 45.0 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EON99374.1 - 1.5e-19 68.0 8.5 0.00026 21.2 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EON99374.1 - 1.8e-19 69.5 11.6 0.001 19.3 0.0 6.9 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EON99374.1 - 2e-15 56.5 12.4 0.0013 19.1 0.0 7.2 6 1 1 7 7 7 5 Ankyrin repeat SPX PF03105.19 EON99374.1 - 3e-11 43.9 8.5 2.9e-09 37.3 1.8 2.1 1 1 1 2 2 2 2 SPX domain GDPD PF03009.17 EON99374.1 - 4e-07 30.0 0.0 3.9e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family SLAC1 PF03595.17 EON99375.1 - 4.3e-40 137.9 19.5 4.6e-21 75.4 4.1 2.0 1 1 1 2 2 2 2 Voltage-dependent anion channel DUF2975 PF11188.8 EON99375.1 - 0.043 13.7 0.8 0.096 12.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) DUF3549 PF12069.8 EON99376.1 - 0.082 11.9 1.2 0.089 11.8 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) Pro_isomerase PF00160.21 EON99378.1 - 2.4e-44 151.4 0.0 2.7e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_L30 PF00327.20 EON99379.1 - 3.1e-17 62.2 0.1 3.9e-17 61.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Meth_synt_2 PF01717.18 EON99381.1 - 7.1e-154 511.9 0.0 3.7e-148 493.1 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EON99381.1 - 5.5e-119 397.3 0.1 1.4e-111 373.0 0.0 3.4 4 0 0 4 4 4 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 EON99381.1 - 0.00012 21.3 0.0 0.016 14.3 0.0 2.4 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) VbhA PF18495.1 EON99381.1 - 0.053 13.4 0.0 6.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Antitoxin VbhA ADH_zinc_N PF00107.26 EON99382.1 - 8.4e-25 87.2 0.1 1.4e-24 86.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON99382.1 - 3.9e-16 60.3 0.0 6.9e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON99382.1 - 6.1e-10 39.0 0.0 1.3e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 EON99382.1 - 0.091 13.0 0.0 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain DLP_helical PF18709.1 EON99383.1 - 0.00061 19.1 10.0 0.00061 19.1 10.0 1.8 2 0 0 2 2 2 1 Dynamin-like helical domain V_ATPase_I PF01496.19 EON99383.1 - 0.015 13.3 9.0 0.02 12.9 9.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rootletin PF15035.6 EON99383.1 - 0.035 14.1 18.4 0.064 13.3 18.4 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ISG65-75 PF11727.8 EON99383.1 - 0.068 12.4 16.6 0.017 14.4 8.4 2.3 1 1 1 2 2 2 0 Invariant surface glycoprotein GAS PF13851.6 EON99383.1 - 0.16 11.3 21.6 0.5 9.7 21.2 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding IFT57 PF10498.9 EON99383.1 - 0.2 10.6 12.8 0.39 9.6 12.8 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Arfaptin PF06456.13 EON99383.1 - 0.22 11.1 7.2 0.43 10.1 7.2 1.4 1 0 0 1 1 1 0 Arfaptin-like domain Lebercilin PF15619.6 EON99383.1 - 0.23 11.1 21.4 0.49 10.0 21.4 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Sec34 PF04136.15 EON99383.1 - 0.23 11.3 10.6 0.66 9.9 10.6 1.7 1 0 0 1 1 1 0 Sec34-like family YabA PF06156.13 EON99383.1 - 0.27 11.9 9.6 0.12 13.0 6.3 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Hamartin PF04388.12 EON99383.1 - 0.51 8.9 18.8 0.66 8.6 18.8 1.1 1 0 0 1 1 1 0 Hamartin protein Prominin PF05478.11 EON99383.1 - 0.69 7.8 14.0 0.9 7.4 14.0 1.1 1 0 0 1 1 1 0 Prominin DUF2333 PF10095.9 EON99383.1 - 1.4 7.9 12.8 2.8 6.9 12.8 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) OmpH PF03938.14 EON99383.1 - 1.6 9.1 37.5 0.11 12.8 10.4 2.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Macoilin PF09726.9 EON99383.1 - 2.4 6.6 17.7 3.8 6.0 17.7 1.3 1 0 0 1 1 1 0 Macoilin family FH2 PF02181.23 EON99383.1 - 4.2 6.4 14.3 7.2 5.6 9.4 2.3 2 1 0 2 2 2 0 Formin Homology 2 Domain Tropomyosin PF00261.20 EON99383.1 - 4.3 6.6 20.6 0.68 9.2 12.3 2.3 2 0 0 2 2 2 0 Tropomyosin DUF2207 PF09972.9 EON99383.1 - 4.7 5.8 5.4 5.4 5.7 0.1 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF4618 PF15397.6 EON99383.1 - 5 6.5 20.1 1.2 8.5 9.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF4200 PF13863.6 EON99383.1 - 8.4 6.8 18.3 0.61 10.5 5.9 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) CorA PF01544.18 EON99383.1 - 8.5 5.6 16.6 4.9 6.4 11.1 2.5 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Exonuc_VII_L PF02601.15 EON99383.1 - 9.7 5.7 29.3 33 3.9 29.3 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit Diphthamide_syn PF01866.17 EON99384.1 - 7.8e-79 265.2 0.0 1e-78 264.9 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Metallophos_2 PF12850.7 EON99385.1 - 1.4e-12 48.1 0.0 1.8e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EON99385.1 - 0.078 13.5 0.0 0.75 10.2 0.0 1.9 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase GCN5L1 PF06320.13 EON99386.1 - 1.4e-19 70.4 1.2 2.1e-19 69.8 1.2 1.3 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Rootletin PF15035.6 EON99386.1 - 0.033 14.2 0.1 0.05 13.6 0.1 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF3450 PF11932.8 EON99386.1 - 0.054 12.8 2.3 0.1 11.9 2.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Serglycin PF04360.12 EON99386.1 - 0.22 11.5 1.8 0.19 11.7 0.3 1.7 2 0 0 2 2 2 0 Serglycin TFIIA PF03153.13 EON99386.1 - 1.3 8.9 8.0 1.8 8.4 8.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PITH PF06201.13 EON99387.1 - 1e-48 165.4 0.1 1.2e-48 165.2 0.1 1.1 1 0 0 1 1 1 1 PITH domain Ribosomal_L3 PF00297.22 EON99388.1 - 1.2e-13 50.9 2.7 4e-11 42.5 0.8 2.3 1 1 1 2 2 2 2 Ribosomal protein L3 NUDIX PF00293.28 EON99389.1 - 2e-17 63.5 2.0 2.4e-17 63.2 2.0 1.0 1 0 0 1 1 1 1 NUDIX domain adh_short PF00106.25 EON99390.1 - 3.8e-22 78.7 0.1 4.1e-19 68.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON99390.1 - 1.1e-11 44.8 0.0 6.9e-09 35.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON99390.1 - 7.6e-08 32.5 0.0 1.2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EON99390.1 - 0.14 11.3 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EON99390.1 - 0.17 11.3 0.5 0.28 10.6 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Coa1 PF08695.10 EON99391.1 - 1.2e-41 141.1 0.0 1.5e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ketoacyl-synt PF00109.26 EON99392.1 - 2.5e-63 214.0 1.0 4.9e-63 213.1 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EON99392.1 - 8.7e-31 106.4 0.0 2e-30 105.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 EON99392.1 - 4.1e-27 95.5 0.9 7.4e-27 94.7 0.9 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 EON99392.1 - 4.3e-27 94.9 0.0 7e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein HTH_51 PF18558.1 EON99392.1 - 1.5e-19 69.6 0.0 3.8e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain PP-binding PF00550.25 EON99392.1 - 6.5e-11 42.4 1.7 1.1e-10 41.7 0.7 1.9 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 EON99392.1 - 6.7e-11 42.8 0.0 2.4e-10 41.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 EON99392.1 - 1.5e-09 38.0 3.6 3.5e-07 30.2 0.1 3.5 4 0 0 4 4 4 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Epimerase PF01370.21 EON99392.1 - 1.7e-09 37.5 0.1 5.8e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 EON99392.1 - 2.9e-09 37.5 0.0 3.4e-08 34.1 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON99392.1 - 2.5e-07 30.7 0.0 8.4e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON99392.1 - 2.4e-06 28.1 0.0 3.2e-05 24.5 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON99392.1 - 8.6e-05 22.4 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 EON99392.1 - 0.00024 20.6 0.1 0.00057 19.3 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain KR PF08659.10 EON99392.1 - 0.0021 18.0 0.0 0.0073 16.2 0.0 2.0 1 0 0 1 1 1 1 KR domain KAsynt_C_assoc PF16197.5 EON99392.1 - 0.0027 18.1 0.0 0.012 16.1 0.0 2.2 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Polysacc_synt_2 PF02719.15 EON99392.1 - 0.052 12.7 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 EON99392.1 - 0.061 13.5 0.2 0.3 11.2 0.1 2.3 2 0 0 2 2 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_28 PF02636.17 EON99392.1 - 0.079 12.6 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase GDP_Man_Dehyd PF16363.5 EON99392.1 - 0.18 11.2 0.0 1.2 8.5 0.0 2.2 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase TPR_2 PF07719.17 EON99394.1 - 3.1e-11 42.5 8.9 0.00049 20.0 1.2 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EON99394.1 - 1.3e-10 40.6 0.4 0.00038 20.2 0.7 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EON99394.1 - 5.2e-09 36.6 0.7 5.2e-09 36.6 0.7 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EON99394.1 - 1.3e-06 28.0 0.1 0.17 12.0 0.1 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EON99394.1 - 7.6e-06 26.1 5.3 0.02 15.2 0.3 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EON99394.1 - 3.1e-05 24.4 2.6 0.0024 18.4 0.1 3.5 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EON99394.1 - 3.1e-05 23.5 0.2 0.0039 16.8 0.0 4.2 5 1 1 6 6 6 1 TPR repeat TPR_14 PF13428.6 EON99394.1 - 0.00011 22.7 0.9 0.0074 17.0 0.2 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EON99394.1 - 0.00089 19.3 1.4 0.56 10.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EON99394.1 - 0.0011 19.1 0.1 0.0011 19.1 0.1 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EON99394.1 - 0.056 13.3 5.1 0.1 12.5 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EON99394.1 - 0.1 13.3 0.8 21 6.0 0.2 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat LIP PF03583.14 EON99395.1 - 5.2e-51 173.7 0.1 7e-51 173.2 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase L-fibroin PF05849.11 EON99395.1 - 0.077 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Fibroin light chain (L-fibroin) FYVE PF01363.21 EON99396.1 - 3e-23 81.7 20.0 3e-17 62.5 5.8 2.3 2 0 0 2 2 2 2 FYVE zinc finger Rbsn PF11464.8 EON99396.1 - 6.5e-19 67.4 1.4 1.6e-18 66.2 1.4 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 EON99396.1 - 0.00033 20.8 2.1 0.00033 20.8 2.1 3.9 4 1 1 5 5 4 1 AN1-like Zinc finger Seryl_tRNA_N PF02403.22 EON99396.1 - 0.026 14.7 3.1 0.029 14.6 0.7 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Csm1_N PF18504.1 EON99396.1 - 0.1 12.9 5.8 2.8 8.4 0.0 3.3 3 0 0 3 3 3 0 Csm1 N-terminal domain bZIP_1 PF00170.21 EON99396.1 - 0.15 12.1 0.2 0.15 12.1 0.2 4.0 3 1 1 4 4 4 0 bZIP transcription factor ABC_tran_CTD PF16326.5 EON99396.1 - 0.29 11.4 9.3 4.8 7.5 0.2 3.2 2 1 0 2 2 2 0 ABC transporter C-terminal domain HrpB2 PF09487.10 EON99396.1 - 0.38 11.2 2.1 6.9 7.1 0.1 3.0 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB2) ATG16 PF08614.11 EON99396.1 - 0.65 10.2 9.3 0.12 12.6 1.7 2.8 2 1 0 3 3 3 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 EON99396.1 - 1.1 9.4 10.5 0.89 9.8 4.0 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 EON99396.1 - 1.6 8.8 3.3 1 9.4 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) HypA PF01155.19 EON99396.1 - 1.7 8.7 10.1 0.95 9.5 0.3 3.1 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Wtap PF17098.5 EON99396.1 - 2.2 8.2 6.3 1.4 8.8 2.4 2.3 2 0 0 2 2 2 0 WTAP/Mum2p family SlyX PF04102.12 EON99396.1 - 4.2 8.1 6.7 23 5.7 0.0 3.8 3 1 0 3 3 3 0 SlyX FYVE_2 PF02318.16 EON99396.1 - 7.4 6.8 13.8 0.96 9.7 0.7 3.6 3 0 0 3 3 3 0 FYVE-type zinc finger C6_DPF PF10170.9 EON99396.1 - 7.4 7.0 8.4 0.35 11.3 0.3 2.8 3 1 0 3 3 3 0 Cysteine-rich domain Sugar_tr PF00083.24 EON99397.1 - 8.7e-70 235.8 25.4 9.8e-70 235.6 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON99397.1 - 5.5e-16 58.4 32.1 1.2e-15 57.4 28.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TraP PF07296.11 EON99397.1 - 0.0012 18.1 0.0 0.0031 16.7 0.0 1.6 1 0 0 1 1 1 1 TraP protein MFS_1 PF07690.16 EON99398.1 - 2.5e-27 95.8 24.5 2.9e-16 59.4 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_4 PF13637.6 EON99399.1 - 5.8e-15 55.5 1.2 3.1e-09 37.2 0.1 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EON99399.1 - 4.1e-10 40.1 0.2 0.00057 20.4 0.1 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EON99399.1 - 4.4e-09 36.4 3.4 0.046 14.2 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EON99399.1 - 6.2e-09 35.4 3.5 0.046 14.3 0.0 5.4 5 1 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EON99399.1 - 1.5e-07 31.5 0.8 0.015 15.6 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 EON99399.1 - 4.4e-05 23.3 0.5 0.00037 20.3 0.5 2.6 1 1 0 1 1 1 1 KilA-N domain NPV_P10 PF05531.12 EON99399.1 - 0.095 13.2 4.8 5 7.6 1.4 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fez1 PF06818.15 EON99399.1 - 0.16 12.4 9.6 0.54 10.7 9.7 1.8 1 1 0 1 1 1 0 Fez1 FliD_C PF07195.12 EON99399.1 - 0.21 11.0 5.5 1.3 8.3 2.7 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Filament PF00038.21 EON99399.1 - 0.38 10.3 7.5 1.9 8.0 4.5 2.2 1 1 1 2 2 2 0 Intermediate filament protein Med9 PF07544.13 EON99399.1 - 0.52 10.4 4.0 2.2 8.5 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Fib_alpha PF08702.10 EON99399.1 - 1.6 8.9 4.9 12 6.1 4.3 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 EON99399.1 - 1.7 9.0 8.3 0.68 10.3 5.1 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GAS PF13851.6 EON99399.1 - 2.2 7.6 10.0 21 4.4 8.9 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Aa_trans PF01490.18 EON99400.1 - 2.4e-29 102.3 34.5 2.9e-29 102.0 34.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sugar_tr PF00083.24 EON99401.1 - 5.6e-71 239.7 11.9 6.4e-71 239.6 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Proteasome PF00227.26 EON99402.1 - 5.6e-26 91.2 0.1 6.5e-26 91.0 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Acetyltransf_1 PF00583.25 EON99403.1 - 6.6e-15 55.4 0.0 1.1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EON99403.1 - 1.3e-07 31.4 0.0 2.2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EON99403.1 - 1.1e-06 28.5 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EON99403.1 - 1.4e-06 28.6 0.0 2.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EON99403.1 - 0.00045 20.9 0.0 0.00079 20.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EON99403.1 - 0.014 15.5 0.0 0.39 10.9 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MAGE_N PF12440.8 EON99403.1 - 0.073 13.8 2.5 0.11 13.2 2.5 1.2 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal p450 PF00067.22 EON99404.1 - 9.1e-62 209.3 0.0 1.7e-61 208.4 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 adh_short PF00106.25 EON99405.1 - 1.5e-07 31.1 0.0 2.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON99405.1 - 8.9e-05 22.2 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Inhibitor_I42 PF09394.10 EON99406.1 - 0.064 13.7 0.1 0.16 12.4 0.1 1.7 1 0 0 1 1 1 0 Chagasin family peptidase inhibitor I42 Complex1_LYR PF05347.15 EON99407.1 - 8.8e-07 28.9 0.8 2.2e-06 27.6 0.8 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EON99407.1 - 0.0025 18.5 1.4 0.0071 17.1 1.4 1.9 1 1 0 1 1 1 1 Complex1_LYR-like Sirohm_synth_C PF14823.6 EON99408.1 - 1.3e-26 92.0 0.0 1.9e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.6 EON99408.1 - 6.7e-23 81.1 0.0 1.2e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 EON99408.1 - 2.6e-13 49.2 0.1 5.4e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.21 EON99408.1 - 0.025 13.9 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 ThiF family DUF3783 PF12646.7 EON99408.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) 5_nucleotid_C PF02872.18 EON99409.1 - 7e-39 133.6 0.0 1.2e-38 132.8 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EON99409.1 - 0.00035 21.1 0.0 0.00056 20.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4387 PF14330.6 EON99410.1 - 4.7e-35 120.2 0.0 8.9e-35 119.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 EON99410.1 - 2.8e-08 32.9 0.0 6.4e-08 31.7 0.0 1.5 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA FAD_binding_3 PF01494.19 EON99411.1 - 4.7e-10 39.3 0.2 0.0033 16.7 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 EON99411.1 - 1e-06 28.2 1.5 0.00013 21.3 0.3 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON99411.1 - 1.1e-05 24.7 0.2 2e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EON99411.1 - 1.3e-05 24.5 0.2 3.6e-05 23.0 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EON99411.1 - 4.7e-05 23.5 0.2 0.00018 21.7 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EON99411.1 - 0.00024 20.4 1.8 0.024 13.9 0.1 2.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON99411.1 - 0.0018 17.1 0.2 0.0069 15.1 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EON99411.1 - 0.0069 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EON99411.1 - 0.015 14.9 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EON99411.1 - 0.031 13.6 0.4 0.067 12.5 0.4 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EON99411.1 - 0.047 14.3 0.8 0.11 13.0 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N_2 PF16884.5 EON99413.1 - 1.5e-24 85.9 0.0 3.3e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EON99413.1 - 1e-21 77.3 0.0 1.7e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON99413.1 - 8.7e-08 33.3 0.0 2e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EON99414.1 - 4.3e-46 156.9 0.0 5.9e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON99414.1 - 5.1e-31 108.0 0.0 6.6e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON99414.1 - 1.2e-05 25.3 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EON99414.1 - 1.3e-05 25.2 0.2 1.9e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 EON99414.1 - 0.029 13.7 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EON99414.1 - 0.034 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 EON99415.1 - 5e-17 61.8 16.1 7.1e-17 61.4 16.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Amidohydro_1 PF01979.20 EON99416.1 - 7.2e-28 97.9 0.0 3.1e-27 95.8 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EON99416.1 - 2.6e-13 50.3 0.1 1.7e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Cpn60_TCP1 PF00118.24 EON99417.1 - 2.4e-141 471.8 12.8 2.7e-141 471.6 12.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 EON99417.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat DUF5442 PF17514.2 EON99417.1 - 0.12 12.6 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5442) Peptidase_S28 PF05577.12 EON99418.1 - 0.00042 19.2 0.1 0.004 16.0 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 CVNH PF08881.10 EON99419.1 - 1.3e-16 61.2 0.1 1.5e-16 60.9 0.1 1.1 1 0 0 1 1 1 1 CVNH domain FA_desaturase PF00487.24 EON99420.1 - 1.9e-22 80.3 23.4 5.2e-22 78.9 23.4 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EON99420.1 - 2e-07 31.3 0.0 9.1e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) eIF2A PF08662.11 EON99421.1 - 2.4e-36 125.5 3.6 3e-35 121.9 0.2 3.8 4 2 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EON99421.1 - 0.00019 21.2 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EON99421.1 - 0.11 13.4 0.4 3.4 8.7 0.0 3.4 4 0 0 4 4 4 0 WD domain, G-beta repeat Prenyltrans PF00432.21 EON99422.1 - 9.5e-33 111.6 12.6 1.2e-06 28.2 0.0 6.8 6 2 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EON99422.1 - 0.18 10.9 0.0 2.9 6.9 0.0 2.6 2 1 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain Ilm1 PF10311.9 EON99423.1 - 1.4e-69 233.0 0.4 1.6e-69 232.8 0.4 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 DAPG_hydrolase PF18089.1 EON99423.1 - 0.073 12.6 0.6 0.095 12.2 0.6 1.2 1 0 0 1 1 1 0 DAPG hydrolase PhiG domain Pkinase PF00069.25 EON99424.1 - 1.4e-51 175.4 0.0 1.9e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON99424.1 - 1.4e-29 103.2 0.0 1.9e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EON99424.1 - 7.8e-08 32.0 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EON99424.1 - 2.1e-05 23.7 0.0 3.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EON99424.1 - 0.0011 19.0 0.5 0.0066 16.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EON99424.1 - 0.0019 17.6 0.4 0.005 16.2 0.0 1.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EON99424.1 - 0.063 12.8 0.4 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 EON99424.1 - 0.091 12.3 0.0 0.091 12.3 0.0 2.1 3 0 0 3 3 3 0 RIO1 family Ferlin_C PF16165.5 EON99424.1 - 0.1 12.5 1.4 0.17 11.9 1.4 1.2 1 0 0 1 1 1 0 Ferlin C-terminus IF-2B PF01008.17 EON99425.1 - 6.3e-71 238.9 0.5 7.5e-71 238.6 0.5 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family RabGAP-TBC PF00566.18 EON99426.1 - 2.1e-19 70.1 0.0 2.5e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain NatB_MDM20 PF09797.9 EON99427.1 - 5.3e-37 127.7 0.0 2.4e-17 63.0 0.1 2.6 2 1 1 3 3 3 2 N-acetyltransferase B complex (NatB) non catalytic subunit Peptidase_M20 PF01546.28 EON99428.1 - 9.5e-21 74.4 0.2 6.8e-20 71.7 0.2 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EON99428.1 - 3.7e-17 62.2 0.0 6.1e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EON99428.1 - 0.002 17.8 0.0 0.0045 16.7 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M35 PF02102.15 EON99430.1 - 1.4e-91 307.0 19.1 1.7e-91 306.8 19.1 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EON99430.1 - 2.2e-40 138.6 10.5 4.3e-40 137.6 10.5 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase CARDB PF07705.11 EON99430.1 - 0.064 13.5 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 CARDB Borrelia_P83 PF05262.11 EON99431.1 - 1.2 7.5 38.7 1.6 7.1 38.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_S64 PF08192.11 EON99431.1 - 3.4 6.0 19.0 5.2 5.4 19.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 ISG65-75 PF11727.8 EON99433.1 - 2.2 7.5 19.0 1 8.5 16.4 1.7 2 1 0 2 2 2 0 Invariant surface glycoprotein Alanine_zipper PF11839.8 EON99433.1 - 8.9 6.8 29.5 1.1 9.7 17.5 2.4 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein FAD_binding_3 PF01494.19 EON99435.1 - 1.9e-25 89.9 0.0 3.7e-25 88.9 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain SnoaL_2 PF12680.7 EON99435.1 - 3.9e-11 43.5 0.4 1.1e-10 42.1 0.4 1.8 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EON99435.1 - 2.1e-10 40.5 0.0 1.8e-09 37.5 0.1 2.5 2 1 0 2 2 2 1 SnoaL-like polyketide cyclase NAD_binding_8 PF13450.6 EON99435.1 - 3.8e-08 33.5 0.2 1.1e-07 31.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EON99435.1 - 2.7e-06 27.0 0.2 0.018 14.4 0.1 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EON99435.1 - 2.1e-05 23.9 0.0 3.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EON99435.1 - 0.00014 21.5 0.2 0.0008 19.1 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON99435.1 - 0.00015 21.0 1.5 0.00025 20.3 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EON99435.1 - 0.011 14.5 0.1 0.02 13.6 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 EON99435.1 - 0.011 14.8 0.0 1.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 EON99435.1 - 0.028 13.5 0.3 0.04 13.0 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EON99435.1 - 0.033 13.5 0.0 0.22 10.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 EON99435.1 - 0.084 12.4 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_9 PF13454.6 EON99435.1 - 0.098 12.6 0.6 1.4 8.9 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding P22_portal PF16510.5 EON99435.1 - 0.21 10.2 0.0 0.28 9.7 0.0 1.1 1 0 0 1 1 1 0 Phage P22-like portal protein Thi4 PF01946.17 EON99435.1 - 0.21 10.8 0.0 0.47 9.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 EON99435.1 - 0.26 11.1 0.1 0.45 10.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain APH PF01636.23 EON99437.1 - 5.9e-11 42.7 0.2 7.9e-11 42.3 0.2 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EON99437.1 - 7.4e-05 22.4 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EON99437.1 - 0.19 11.0 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase FTA2 PF13095.6 EON99438.1 - 9.1e-73 244.4 0.0 1.5e-72 243.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 MFS_1 PF07690.16 EON99440.1 - 2.2e-18 66.3 12.2 2.2e-18 66.3 12.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily CcmD PF04995.14 EON99440.1 - 0.05 13.7 0.0 0.05 13.7 0.0 2.8 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) DUF3040 PF11239.8 EON99440.1 - 0.055 13.7 0.3 0.055 13.7 0.3 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) RRM_1 PF00076.22 EON99441.1 - 1e-23 82.9 0.3 1.9e-11 43.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EON99441.1 - 0.00023 21.1 0.1 0.84 9.7 0.0 2.7 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.11 EON99441.1 - 0.0034 16.8 0.7 0.0082 15.6 0.7 1.6 1 0 0 1 1 1 1 Lsm interaction motif RL PF17797.1 EON99441.1 - 0.023 14.6 0.1 0.073 13.0 0.1 1.8 1 0 0 1 1 1 0 RL domain TPR_14 PF13428.6 EON99441.1 - 2.3 9.2 6.8 29 5.8 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Fasciclin PF02469.22 EON99442.1 - 4.2e-38 130.5 0.0 2.9e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain LTD PF00932.19 EON99442.1 - 0.069 13.5 0.1 0.2 12.0 0.1 1.8 1 0 0 1 1 1 0 Lamin Tail Domain DUF3452 PF11934.8 EON99442.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) WD40 PF00400.32 EON99443.1 - 2.1e-44 148.6 24.8 2.7e-08 34.3 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON99443.1 - 6.2e-09 36.0 0.5 0.072 13.4 0.0 4.4 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EON99443.1 - 0.00022 20.0 6.9 0.067 11.8 0.1 4.3 2 1 1 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EON99443.1 - 0.0062 15.5 0.1 10 4.9 0.0 3.8 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EON99443.1 - 0.01 15.2 0.0 0.53 9.6 0.0 2.6 2 1 2 4 4 4 0 WD40-like domain PD40 PF07676.12 EON99443.1 - 0.018 15.0 0.4 22 5.1 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat MR_MLE_C PF13378.6 EON99444.1 - 1.2e-41 142.7 0.0 1.7e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EON99444.1 - 1.1e-09 38.5 0.0 1.9e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Amidase PF01425.21 EON99445.1 - 3.2e-65 220.9 0.5 1.9e-63 215.0 0.1 2.1 2 0 0 2 2 2 2 Amidase Aldo_ket_red PF00248.21 EON99445.1 - 7.8e-39 133.6 0.0 1.8e-38 132.4 0.0 1.5 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 EON99447.1 - 6.3e-18 65.1 0.0 1.8e-17 63.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON99447.1 - 0.0018 17.6 0.0 0.0038 16.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH_6_hur PF04655.14 EON99447.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase HA2 PF04408.23 EON99449.1 - 6.1e-15 55.4 0.0 6.1e-15 55.4 0.0 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EON99449.1 - 1.3e-13 51.3 0.0 3.3e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EON99449.1 - 2.4e-12 47.0 0.0 4.5e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EON99449.1 - 1.6e-07 31.7 5.1 1.7e-07 31.6 0.1 3.3 4 0 0 4 4 3 1 AAA domain OB_NTP_bind PF07717.16 EON99449.1 - 0.00032 21.0 0.0 0.00069 19.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 EON99449.1 - 0.0048 17.2 0.2 0.014 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EON99449.1 - 0.01 16.4 0.0 0.03 14.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 EON99449.1 - 0.011 15.1 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 EON99449.1 - 0.041 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 EON99449.1 - 0.048 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 EON99449.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 EON99449.1 - 0.15 11.9 0.0 0.95 9.3 0.0 2.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EON99449.1 - 0.16 12.0 1.2 10 6.1 0.1 3.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EON99449.1 - 0.41 11.2 2.4 16 6.1 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.6 EON99449.1 - 1 9.8 0.0 1 9.8 0.0 2.8 4 0 0 4 4 4 0 AAA domain Amidohydro_1 PF01979.20 EON99450.1 - 4.3e-21 75.6 3.8 4.4e-20 72.3 3.8 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EON99450.1 - 1e-16 61.5 10.6 3e-13 50.1 3.1 2.2 1 1 1 2 2 2 2 Amidohydrolase family NTP_transf_3 PF12804.7 EON99450.1 - 0.0012 19.2 0.7 0.0056 17.0 0.7 2.1 1 1 0 1 1 1 1 MobA-like NTP transferase domain MFS_1 PF07690.16 EON99451.1 - 7.8e-41 140.2 32.1 7.8e-41 140.2 32.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 EON99451.1 - 0.0024 16.4 3.0 0.0037 15.7 3.0 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 EON99451.1 - 0.92 7.7 4.0 2.8 6.1 3.9 1.8 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TMEM61 PF15105.6 EON99452.1 - 0.059 13.2 0.1 0.092 12.6 0.1 1.2 1 0 0 1 1 1 0 TMEM61 protein family Fungal_trans PF04082.18 EON99453.1 - 1.3e-17 63.7 0.1 1.7e-17 63.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SHMT PF00464.19 EON99455.1 - 1.9e-190 632.6 0.0 2.5e-190 632.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 EON99455.1 - 0.0098 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EON99455.1 - 0.058 12.7 0.0 0.16 11.3 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase 2OG-FeII_Oxy_2 PF13532.6 EON99456.1 - 7.4e-28 98.1 0.2 2.6e-27 96.3 0.2 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 EON99456.1 - 3.3e-23 82.7 0.0 1.3e-22 80.9 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family WD40 PF00400.32 EON99457.1 - 8.7e-30 102.3 8.8 3.4e-05 24.5 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON99457.1 - 4e-11 43.1 0.1 0.00041 20.6 0.0 4.0 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EON99457.1 - 0.023 13.4 0.7 5.7 5.6 0.1 2.9 1 1 3 4 4 4 0 Nup133 N terminal like WD40_like PF17005.5 EON99457.1 - 0.032 13.6 0.3 2.4 7.4 0.1 3.2 1 1 2 3 3 3 0 WD40-like domain PQQ_2 PF13360.6 EON99457.1 - 0.039 13.5 0.6 1.2 8.6 0.1 2.2 2 1 0 2 2 2 0 PQQ-like domain Ribosomal_L19e PF01280.20 EON99459.1 - 1.1e-60 203.9 5.1 1.1e-60 203.9 5.1 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e TRAPP PF04051.16 EON99461.1 - 1e-34 119.3 0.1 1.3e-34 119.0 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 EON99461.1 - 0.012 14.5 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A CUB PF00431.20 EON99461.1 - 0.057 13.8 0.0 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 CUB domain Ribosomal_L22 PF00237.19 EON99462.1 - 7e-24 84.0 0.1 1.7e-23 82.8 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Arg_decarbox_C PF17944.1 EON99462.1 - 0.067 13.8 0.7 0.19 12.3 0.1 2.1 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension Gcn1_N PF12074.8 EON99463.1 - 1.1e-54 186.1 14.2 4.6e-38 131.4 0.7 4.5 3 2 2 5 5 5 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 EON99463.1 - 3.3e-34 114.0 36.7 0.014 15.6 0.1 23.0 25 0 0 25 25 23 9 HEAT repeat HEAT_2 PF13646.6 EON99463.1 - 3.4e-31 107.5 52.2 8.8e-06 26.0 3.4 15.3 11 4 6 17 17 17 9 HEAT repeats HEAT_EZ PF13513.6 EON99463.1 - 1.7e-30 105.0 50.7 3.1e-07 30.7 0.0 20.7 17 3 7 24 24 21 8 HEAT-like repeat Cnd1 PF12717.7 EON99463.1 - 2.3e-16 60.3 5.7 0.18 11.9 0.0 10.0 7 3 0 9 9 9 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EON99463.1 - 5.7e-16 58.9 0.0 1.1 9.9 0.1 9.8 7 3 3 10 10 9 4 Vacuolar 14 Fab1-binding region ParcG PF10274.9 EON99463.1 - 3.8e-15 56.5 1.6 6.8e-05 23.1 0.0 6.6 6 1 0 6 6 6 3 Parkin co-regulated protein CLASP_N PF12348.8 EON99463.1 - 4.9e-14 52.4 0.0 0.1 12.2 0.0 6.9 5 1 1 6 6 6 3 CLASP N terminal UME PF08064.13 EON99463.1 - 1.5e-09 37.7 1.7 4.3 7.3 0.0 8.4 8 2 0 8 8 7 2 UME (NUC010) domain Adaptin_N PF01602.20 EON99463.1 - 2.9e-09 36.0 9.3 0.0013 17.3 0.3 7.6 5 3 1 7 7 7 2 Adaptin N terminal region DUF3385 PF11865.8 EON99463.1 - 1.7e-06 28.0 0.0 1.1 9.2 0.0 6.6 6 1 0 6 6 6 1 Domain of unknown function (DUF3385) MMS19_C PF12460.8 EON99463.1 - 7.9e-06 25.2 25.1 0.00047 19.4 0.2 7.9 7 2 2 9 9 9 2 RNAPII transcription regulator C-terminal Ecm29 PF13001.7 EON99463.1 - 1.3e-05 24.1 7.3 0.0053 15.5 0.0 5.2 4 2 1 5 5 5 1 Proteasome stabiliser DUF937 PF06078.11 EON99463.1 - 1.7e-05 25.5 3.0 7.6 7.1 0.0 7.0 5 2 1 6 6 6 1 Bacterial protein of unknown function (DUF937) TIP120 PF08623.10 EON99463.1 - 2.8e-05 24.0 0.3 0.07 12.9 0.0 5.5 5 1 0 5 5 5 1 TATA-binding protein interacting (TIP20) Tti2 PF10521.9 EON99463.1 - 0.00058 19.5 5.9 0.37 10.3 0.0 6.7 8 1 0 8 8 7 1 Tti2 family FANCI_S2 PF14676.6 EON99463.1 - 0.012 16.0 2.2 0.43 10.9 0.1 4.4 3 1 2 5 5 5 0 FANCI solenoid 2 Ipi1_N PF12333.8 EON99463.1 - 0.039 14.5 0.3 0.96 10.1 0.0 3.6 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation ADSL_C PF10397.9 EON99463.1 - 0.17 12.4 2.3 9.9 6.8 0.0 4.5 3 0 0 3 3 3 0 Adenylosuccinate lyase C-terminus HEAT_PBS PF03130.16 EON99463.1 - 0.21 12.4 18.9 1.6e+02 3.4 0.2 10.1 8 1 0 8 8 8 0 PBS lyase HEAT-like repeat TFCD_C PF12612.8 EON99463.1 - 0.53 10.1 6.0 4.8 7.0 0.0 4.6 3 1 2 5 5 5 0 Tubulin folding cofactor D C terminal Arm PF00514.23 EON99463.1 - 0.85 9.8 15.2 1.4e+02 2.7 0.1 9.8 9 1 1 10 10 9 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 EON99463.1 - 4.8 6.9 17.1 0.092 12.5 0.3 6.1 6 2 1 7 7 7 0 rRNA processing/ribosome biogenesis DUF4719 PF15843.5 EON99464.1 - 0.049 13.7 0.7 0.082 13.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) Oxidored_FMN PF00724.20 EON99465.1 - 2e-35 122.7 0.0 2.5e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TFB6 PF17110.5 EON99466.1 - 2.6e-65 219.4 0.0 2.9e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Pes-10 PF07149.11 EON99466.1 - 0.25 10.4 0.6 0.31 10.0 0.6 1.1 1 0 0 1 1 1 0 Pes-10 Fungus-induced PF10917.8 EON99467.1 - 0.14 12.5 1.9 0.24 11.7 1.9 1.4 1 0 0 1 1 1 0 Fungus-induced protein DUF3742 PF12553.8 EON99467.1 - 1.3 9.2 4.9 2 8.6 4.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3742) FixH PF05751.11 EON99467.1 - 1.8 8.6 3.9 2.7 8.0 3.9 1.2 1 0 0 1 1 1 0 FixH TPP_enzyme_N PF02776.18 EON99468.1 - 4.9e-44 150.0 2.5 1e-43 148.9 2.5 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EON99468.1 - 1.6e-40 138.4 0.3 4.3e-39 133.8 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EON99468.1 - 2.1e-27 95.5 0.0 4e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 EON99468.1 - 0.0092 15.7 1.4 0.014 15.1 1.4 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Pkinase_Tyr PF07714.17 EON99469.1 - 2.9e-18 66.1 0.0 2.9e-16 59.5 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EON99469.1 - 3.6e-15 56.1 0.0 4e-14 52.6 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 EON99469.1 - 6.5e-15 54.6 2.4 2.3e-07 30.5 0.8 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EON99469.1 - 6.8e-09 35.9 4.1 0.08 13.4 0.0 4.7 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) Kdo PF06293.14 EON99469.1 - 6.3e-06 25.7 0.1 1e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EON99469.1 - 0.0023 17.9 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EON99469.1 - 0.0028 17.3 0.0 0.0065 16.1 0.0 1.5 2 0 0 2 2 2 1 RIO1 family LRR_9 PF14580.6 EON99469.1 - 0.0072 15.8 0.0 0.24 10.9 0.0 2.1 1 1 0 2 2 2 1 Leucine-rich repeat Kinase-like PF14531.6 EON99469.1 - 0.017 14.5 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like LRR_1 PF00560.33 EON99469.1 - 8.6 7.4 6.5 1.5e+02 3.5 0.2 4.5 3 2 0 3 3 3 0 Leucine Rich Repeat ADH_N PF08240.12 EON99470.1 - 6.5e-19 67.8 0.9 2.5e-18 65.9 0.8 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 EON99470.1 - 3.5e-11 42.8 0.6 3.5e-11 42.8 0.6 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 EON99470.1 - 1.7e-06 28.0 0.0 0.00044 20.2 0.0 3.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Glyco_hydro_16 PF00722.21 EON99471.1 - 3.2e-17 62.6 0.1 4.4e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EON99471.1 - 2.2e-09 36.2 0.1 4.2e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.9 EON99471.1 - 0.042 13.4 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) Bromo_TP PF07524.13 EON99472.1 - 6.4e-16 58.1 0.1 1.2e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 EON99472.1 - 3e-13 50.1 2.1 4.1e-07 30.5 0.5 2.7 2 0 0 2 2 2 2 Transcription factor TFIID complex subunit 8 C-term DUF2397 PF09660.10 EON99472.1 - 0.032 13.1 2.0 0.046 12.6 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2397) Bromo_TP_like PF17027.5 EON99472.1 - 0.054 13.7 0.0 0.093 12.9 0.0 1.3 1 0 0 1 1 1 0 Histone-fold protein adh_short_C2 PF13561.6 EON99473.1 - 5.3e-50 170.2 0.0 8.3e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON99473.1 - 4.9e-39 133.8 0.0 6.8e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON99473.1 - 6.8e-07 29.4 0.1 1.1e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 EON99474.1 - 8.1e-31 107.2 41.4 8.1e-31 107.2 41.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4407 PF14362.6 EON99474.1 - 0.21 10.9 0.4 0.4 10.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MFS_1 PF07690.16 EON99475.1 - 8.9e-34 116.9 31.5 1.2e-33 116.5 31.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.6 EON99475.1 - 0.23 11.1 4.1 0.069 12.8 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SPC12 PF06645.13 EON99475.1 - 2 8.5 5.7 5.5 7.1 1.1 3.6 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) LisH PF08513.11 EON99476.1 - 0.11 12.4 1.4 0.24 11.4 1.4 1.5 1 0 0 1 1 1 0 LisH GAGA_bind PF06217.12 EON99476.1 - 0.57 10.4 16.7 0.19 11.9 1.8 2.5 2 0 0 2 2 2 0 GAGA binding protein-like family Ribosomal_L32p PF01783.23 EON99476.1 - 5.9 7.2 11.1 0.14 12.4 3.5 2.1 2 0 0 2 2 2 0 Ribosomal L32p protein family Methyltransf_12 PF08242.12 EON99477.1 - 0.027 15.2 0.2 0.032 15.0 0.2 1.1 1 0 0 1 1 1 0 Methyltransferase domain DUF1996 PF09362.10 EON99478.1 - 1.8e-33 116.5 2.5 3.7e-23 82.8 0.4 2.9 1 1 1 2 2 2 2 Domain of unknown function (DUF1996) zf-CCHC PF00098.23 EON99479.1 - 2.6e-45 150.5 60.8 5.8e-08 32.5 2.5 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EON99479.1 - 4.9e-10 39.0 39.0 0.16 11.7 1.1 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 EON99479.1 - 3e-05 23.9 43.0 0.046 13.7 0.0 6.9 4 2 1 5 5 5 3 Zinc knuckle zf-CCHC_5 PF14787.6 EON99479.1 - 0.00027 20.6 45.1 0.0067 16.1 1.0 7.1 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 EON99479.1 - 0.028 14.3 0.1 0.028 14.3 0.1 6.8 6 1 1 7 7 7 0 Zinc knuckle zf-CCHC_2 PF13696.6 EON99479.1 - 0.058 13.2 2.0 0.058 13.2 2.0 7.2 7 0 0 7 7 7 0 Zinc knuckle Hydrolase_6 PF13344.6 EON99480.1 - 7.4e-23 80.6 0.0 1.5e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EON99480.1 - 1.4e-13 50.7 0.0 7.9e-13 48.3 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EON99480.1 - 0.01 16.1 0.0 3.1 8.0 0.0 2.4 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Glyco_hydro_125 PF06824.11 EON99481.1 - 5.2e-172 572.4 0.2 6.7e-172 572.1 0.2 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Peptidase_M20 PF01546.28 EON99483.1 - 2.7e-07 30.5 0.4 5.2e-07 29.6 0.4 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EON99483.1 - 0.00045 20.1 0.0 0.00092 19.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Arginase PF00491.21 EON99485.1 - 4.4e-85 285.6 0.4 5.7e-85 285.2 0.4 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EON99485.1 - 0.044 14.0 0.7 0.078 13.2 0.7 1.3 1 0 0 1 1 1 0 UPF0489 domain ABM PF03992.16 EON99487.1 - 2.4e-05 24.4 0.0 0.0099 16.0 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase AA_permease_2 PF13520.6 EON99488.1 - 2.5e-62 211.1 52.0 2.9e-62 210.9 52.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EON99488.1 - 2.7e-18 65.9 45.6 3.6e-18 65.4 45.6 1.1 1 0 0 1 1 1 1 Amino acid permease Sirohm_synth_M PF14824.6 EON99488.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central Peptidase_S29 PF02907.15 EON99489.1 - 0.0032 17.2 0.1 0.0063 16.3 0.1 1.5 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Peptidase_S64 PF08192.11 EON99489.1 - 0.0033 16.0 0.1 0.011 14.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase family S64 Arginase PF00491.21 EON99492.1 - 2.3e-65 220.9 0.2 2.5e-65 220.8 0.2 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EON99492.1 - 0.028 14.6 0.1 0.04 14.2 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain DUF1079 PF06435.11 EON99495.1 - 0.0057 16.8 4.9 0.014 15.6 4.9 1.6 1 0 0 1 1 1 1 Repeat of unknown function (DUF1079) zf-CCCH PF00642.24 EON99496.1 - 6.9e-08 32.2 2.4 1.3e-07 31.3 2.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 EON99496.1 - 5.3e-07 29.4 4.5 9.4e-07 28.6 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EON99496.1 - 4e-06 26.6 7.7 7.2e-06 25.8 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EON99496.1 - 4.5e-06 26.4 6.9 9e-06 25.4 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EON99496.1 - 4.8e-06 26.5 6.2 9.7e-06 25.5 6.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EON99496.1 - 9.4e-06 25.5 6.6 1.7e-05 24.7 6.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 EON99496.1 - 2.6e-05 24.1 6.4 5.4e-05 23.1 6.4 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 EON99496.1 - 0.00012 22.1 2.3 0.00012 22.1 2.3 1.7 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-CCCH_4 PF18044.1 EON99496.1 - 0.00019 21.1 2.6 0.00037 20.2 2.6 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-RING_2 PF13639.6 EON99496.1 - 0.00057 20.2 6.2 0.001 19.3 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EON99496.1 - 0.029 14.2 4.8 0.054 13.4 4.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Harakiri PF15196.6 EON99496.1 - 0.031 14.7 1.0 0.073 13.5 1.0 1.6 1 0 0 1 1 1 0 Activator of apoptosis harakiri zf-CCCH_2 PF14608.6 EON99496.1 - 0.17 12.4 2.9 0.38 11.3 2.9 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-C3HC4_4 PF15227.6 EON99496.1 - 0.34 11.1 7.6 0.84 9.8 7.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING p450 PF00067.22 EON99497.1 - 2.2e-53 181.7 0.0 2.8e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EON99498.1 - 4.2e-21 75.5 0.0 7.1e-18 64.9 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EON99498.1 - 1.6e-06 27.7 0.0 5.3e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase IIGP PF05049.13 EON99500.1 - 1.5e-17 63.7 0.2 2.5e-17 63.0 0.1 1.3 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 EON99500.1 - 7.8e-08 32.4 0.0 2.9e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EON99500.1 - 0.017 15.2 11.3 0.19 11.8 2.0 3.1 2 1 0 2 2 2 0 Dynamin family NACHT_sigma PF17106.5 EON99500.1 - 0.041 14.0 0.6 0.08 13.1 0.6 1.4 1 0 0 1 1 1 0 Sigma domain on NACHT-NTPases ABC_tran PF00005.27 EON99500.1 - 0.064 13.8 1.4 0.48 10.9 0.0 2.6 3 0 0 3 3 3 0 ABC transporter FAM60A PF15396.6 EON99500.1 - 1 9.3 8.4 0.96 9.4 5.3 2.0 2 0 0 2 2 2 0 Protein Family FAM60A SpecificRecomb PF10136.9 EON99500.1 - 1.3 7.3 4.4 2 6.6 4.4 1.2 1 0 0 1 1 1 0 Site-specific recombinase Hydin_ADK PF17213.3 EON99500.1 - 1.6 9.0 9.6 0.63 10.3 5.5 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Peptidase_S49_N PF08496.10 EON99500.1 - 2 8.5 13.8 0.54 10.3 8.4 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal AAA_11 PF13086.6 EON99500.1 - 7.1 6.3 13.8 9.1 6.0 10.1 2.1 2 0 0 2 2 2 0 AAA domain Pyr_redox_2 PF07992.14 EON99504.1 - 4.4e-08 32.7 0.0 1.8e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EON99504.1 - 0.0054 16.4 0.4 0.0082 15.8 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EON99504.1 - 0.0092 14.7 0.0 0.023 13.4 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 EON99504.1 - 0.0097 15.9 0.0 0.028 14.4 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EON99504.1 - 0.17 10.9 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EON99505.1 - 1.5e-37 129.4 2.6 2e-37 129.0 2.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EON99505.1 - 4.3e-21 75.2 0.0 1.3e-20 73.7 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EON99505.1 - 6.7e-16 58.6 2.7 8.2e-16 58.3 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EON99505.1 - 1.8e-05 24.7 1.0 0.00018 21.5 0.3 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EON99505.1 - 4.1e-05 23.0 0.8 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON99505.1 - 4.7e-05 22.6 4.6 0.037 13.1 0.1 2.6 3 0 0 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.14 EON99505.1 - 0.00023 20.0 6.6 0.06 12.0 0.1 3.0 2 1 1 3 3 3 2 HI0933-like protein 2-Hacid_dh_C PF02826.19 EON99505.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EON99505.1 - 0.0013 17.9 3.5 1.8 7.5 0.1 3.2 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 EON99505.1 - 0.0036 17.5 0.9 1.7 8.9 0.1 3.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.6 EON99505.1 - 0.0046 17.4 0.0 0.009 16.5 0.0 1.5 1 0 0 1 1 1 1 XdhC Rossmann domain NAD_binding_7 PF13241.6 EON99505.1 - 0.0098 16.3 0.6 0.027 14.9 0.2 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EON99505.1 - 0.042 13.4 0.1 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 EON99505.1 - 0.057 12.7 0.5 0.4 9.9 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain F420_oxidored PF03807.17 EON99505.1 - 0.071 13.7 1.7 0.84 10.3 0.1 2.9 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.6 EON99505.1 - 0.28 11.2 4.3 0.48 10.4 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EON99505.1 - 4.5 6.3 9.0 0.29 10.2 0.1 2.6 3 0 0 3 3 3 0 FAD binding domain GP52 PF17468.2 EON99506.1 - 0.16 12.1 0.0 0.51 10.5 0.0 1.9 1 0 0 1 1 1 0 Phage gene product 52 UCH_1 PF13423.6 EON99507.1 - 2.7e-36 125.8 0.0 3.7e-35 122.1 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SelP_N PF04592.14 EON99507.1 - 0.89 8.9 13.5 1.9 7.8 13.5 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NAD_binding_10 PF13460.6 EON99508.1 - 6.1e-20 71.9 0.3 9.7e-20 71.2 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EON99508.1 - 1.4e-18 67.3 0.3 1.8e-18 66.9 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EON99508.1 - 6.5e-06 25.8 0.1 0.0011 18.5 0.1 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EON99508.1 - 0.00026 21.1 0.5 0.00057 20.0 0.5 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 EON99508.1 - 0.0011 19.0 0.0 0.0036 17.4 0.1 1.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EON99508.1 - 0.0018 18.5 0.1 0.003 17.8 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EON99508.1 - 0.15 12.5 0.6 0.58 10.6 0.3 2.1 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain SF1-HH PF16275.5 EON99510.1 - 5.3e-44 149.2 1.1 5.3e-44 149.2 1.1 2.5 1 1 1 2 2 2 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 EON99510.1 - 6.5e-12 44.9 11.1 1.3e-05 25.0 0.8 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 EON99510.1 - 1.3e-08 34.5 0.1 2.8e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 EON99510.1 - 1.5e-06 28.1 6.3 0.002 18.1 3.5 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 EON99510.1 - 0.00031 20.5 7.7 0.078 12.8 0.5 2.8 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EON99510.1 - 0.0013 18.5 5.0 0.42 10.4 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 EON99510.1 - 0.014 15.2 0.5 0.014 15.2 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle FAD_binding_1 PF00667.20 EON99511.1 - 8.3e-45 153.1 0.0 1.3e-44 152.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EON99511.1 - 4.8e-10 40.1 0.0 1.6e-09 38.4 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Peptidase_M28 PF04389.17 EON99512.1 - 1.6e-29 103.0 0.0 2.5e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EON99512.1 - 0.004 16.9 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 YdjM PF04307.14 EON99512.1 - 0.038 13.3 2.2 0.58 9.4 0.3 3.0 3 1 0 3 3 3 0 LexA-binding, inner membrane-associated putative hydrolase Transposase_21 PF02992.14 EON99512.1 - 0.077 12.2 0.1 1 8.5 0.3 2.3 2 0 0 2 2 2 0 Transposase family tnp2 DUF2070 PF09843.9 EON99512.1 - 3.1 6.0 22.4 0.35 9.1 10.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) p450 PF00067.22 EON99514.1 - 1.2e-42 146.2 0.0 1.4e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF2681 PF10883.8 EON99514.1 - 0.13 12.7 0.1 17 5.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Med11 PF10280.9 EON99515.1 - 1.4e-48 164.8 0.2 1.7e-48 164.6 0.2 1.1 1 0 0 1 1 1 1 Mediator complex protein LuxC PF05893.14 EON99517.1 - 0.54 9.2 3.3 0.23 10.4 0.1 1.8 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) SHOCT PF09851.9 EON99518.1 - 0.00029 20.5 0.7 0.14 11.9 0.0 2.8 2 0 0 2 2 2 2 Short C-terminal domain DUF5446 PF17522.2 EON99518.1 - 0.073 13.2 10.3 0.21 11.8 1.6 3.0 3 1 0 3 3 3 0 Family of unknown function (DUF5446) Patched PF02460.18 EON99518.1 - 0.17 9.9 0.0 0.3 9.1 0.0 1.3 1 0 0 1 1 1 0 Patched family Ribosomal_L27A PF00828.19 EON99518.1 - 0.59 10.8 6.9 3.2 8.5 0.0 2.7 3 0 0 3 3 3 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Nop25 PF09805.9 EON99519.1 - 9.2e-43 146.0 14.9 9.2e-43 146.0 14.9 2.3 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) AP-5_subunit_s1 PF15001.6 EON99519.1 - 8 6.4 12.9 0.034 14.2 2.2 2.0 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 Ferritin_2 PF13668.6 EON99520.1 - 3.2e-38 131.0 2.0 5.4e-38 130.3 2.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain LIME1 PF15332.6 EON99520.1 - 0.26 10.8 0.4 0.5 9.9 0.4 1.4 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 GMC_oxred_C PF05199.13 EON99521.1 - 3.1e-08 34.2 0.8 1.9e-07 31.7 0.2 2.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EON99521.1 - 5.8e-06 25.9 0.0 4.3e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EON99521.1 - 0.00066 18.9 0.1 0.0012 18.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EON99521.1 - 0.028 14.7 0.6 0.077 13.2 0.6 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EON99521.1 - 0.036 13.4 0.2 0.059 12.7 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON99521.1 - 0.097 11.9 0.0 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF410 PF04190.13 EON99522.1 - 4.2e-97 324.9 0.0 5.1e-97 324.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RNB PF00773.19 EON99523.1 - 2.7e-80 270.1 0.0 4.6e-80 269.4 0.0 1.4 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 EON99523.1 - 8.6e-26 90.1 0.0 2.6e-25 88.5 0.0 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 EON99523.1 - 1e-25 89.6 0.0 2.4e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EON99523.1 - 5.6e-06 26.4 0.0 0.024 14.8 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 EON99523.1 - 0.011 15.5 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 0 Rrp44-like cold shock domain DUF4239 PF14023.6 EON99523.1 - 0.22 11.3 0.3 0.41 10.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) NPR3 PF03666.13 EON99523.1 - 9.1 4.9 8.8 0.23 10.2 0.8 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 BRCT PF00533.26 EON99525.1 - 6.7e-05 23.2 0.0 0.0001 22.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EON99525.1 - 0.00019 21.3 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 EON99525.1 - 0.0036 17.7 0.0 0.0078 16.6 0.0 1.5 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 EON99525.1 - 0.06 13.4 0.0 11 6.2 0.0 2.4 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Tropomyosin_1 PF12718.7 EON99526.1 - 3.4e-54 182.9 31.8 4.1e-54 182.6 31.8 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EON99526.1 - 3.6e-08 33.1 32.3 9.6e-05 21.9 12.9 3.0 1 1 2 3 3 3 3 Tropomyosin CENP-F_leu_zip PF10473.9 EON99526.1 - 0.00022 21.3 5.4 0.00022 21.3 5.4 2.7 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.11 EON99526.1 - 0.0014 17.6 30.9 0.019 13.9 16.4 2.0 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.11 EON99526.1 - 0.0037 17.5 31.4 1.4 9.1 18.0 2.3 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF4200 PF13863.6 EON99526.1 - 0.0042 17.5 33.8 0.2 12.1 14.9 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4200) DUF724 PF05266.14 EON99526.1 - 0.0048 16.7 25.8 0.028 14.2 8.9 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF724) TACC_C PF05010.14 EON99526.1 - 0.0067 16.2 24.8 0.035 13.9 13.2 2.3 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Spc7 PF08317.11 EON99526.1 - 0.0079 15.1 33.1 0.017 14.0 18.3 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein DUF3450 PF11932.8 EON99526.1 - 0.0093 15.3 27.3 0.2 11.0 9.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) HMMR_N PF15905.5 EON99526.1 - 0.01 15.4 29.3 0.014 14.9 29.3 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal ADIP PF11559.8 EON99526.1 - 0.012 15.8 30.1 0.013 15.6 8.3 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Taxilin PF09728.9 EON99526.1 - 0.013 14.7 30.4 0.37 9.9 9.0 2.0 1 1 1 2 2 2 0 Myosin-like coiled-coil protein KLRAQ PF10205.9 EON99526.1 - 0.016 15.4 22.1 0.055 13.7 8.6 3.1 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein bZIP_1 PF00170.21 EON99526.1 - 0.017 15.2 29.4 1 9.5 8.2 5.1 1 1 3 4 4 4 0 bZIP transcription factor KASH_CCD PF14662.6 EON99526.1 - 0.026 14.3 32.8 0.64 9.8 14.3 2.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 EON99526.1 - 0.026 13.9 32.6 0.17 11.2 13.4 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 EON99526.1 - 0.034 13.8 32.8 0.95 9.1 17.1 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Laminin_II PF06009.12 EON99526.1 - 0.068 13.2 18.7 0.057 13.4 4.4 2.3 1 1 1 2 2 2 0 Laminin Domain II T3SSipB PF16535.5 EON99526.1 - 0.071 13.6 18.1 0.14 12.6 4.0 3.0 1 1 2 3 3 3 0 Type III cell invasion protein SipB Fez1 PF06818.15 EON99526.1 - 0.092 13.2 27.5 0.3 11.5 27.8 1.6 1 1 0 1 1 1 0 Fez1 Syntaxin-6_N PF09177.11 EON99526.1 - 0.1 13.2 19.0 0.21 12.1 6.1 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CENP-K PF11802.8 EON99526.1 - 0.1 12.1 20.4 0.16 11.5 5.6 2.1 1 1 1 2 2 2 0 Centromere-associated protein K FlaC_arch PF05377.11 EON99526.1 - 0.1 13.0 22.0 0.51 10.8 3.2 4.5 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) ERM PF00769.19 EON99526.1 - 0.12 12.2 37.4 0.14 12.0 17.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Alanine_zipper PF11839.8 EON99526.1 - 0.12 12.7 10.9 0.3 11.5 1.4 3.4 2 1 1 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein APG6_N PF17675.1 EON99526.1 - 0.13 12.7 40.1 0.71 10.4 24.7 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region HOOK PF05622.12 EON99526.1 - 0.15 10.1 28.1 0.22 9.6 28.1 1.2 1 0 0 1 1 1 0 HOOK protein TMF_TATA_bd PF12325.8 EON99526.1 - 0.2 11.9 25.8 1.6 8.9 15.3 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Cortex-I_coil PF09304.10 EON99526.1 - 0.21 11.8 23.2 8.1 6.7 6.4 3.2 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF1664 PF07889.12 EON99526.1 - 0.21 11.6 15.4 0.16 12.0 1.5 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 EON99526.1 - 0.23 11.8 35.0 1.7 9.0 14.5 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Seryl_tRNA_N PF02403.22 EON99526.1 - 0.26 11.5 26.3 0.23 11.7 0.5 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain EzrA PF06160.12 EON99526.1 - 0.28 9.3 24.1 0.077 11.2 6.6 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4686 PF15742.5 EON99526.1 - 0.33 10.0 33.2 0.33 10.0 24.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) UPF0242 PF06785.11 EON99526.1 - 0.52 10.4 32.1 1.3 9.1 11.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus XhlA PF10779.9 EON99526.1 - 0.55 10.5 23.5 1.4 9.2 2.2 4.1 2 1 1 4 4 4 0 Haemolysin XhlA Jnk-SapK_ap_N PF09744.9 EON99526.1 - 0.65 10.2 33.2 0.095 12.9 19.5 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Cep57_CLD_2 PF14197.6 EON99526.1 - 0.76 9.9 27.6 0.32 11.1 0.5 4.3 2 2 2 4 4 4 0 Centrosome localisation domain of PPC89 Fmp27_WPPW PF10359.9 EON99526.1 - 0.9 8.3 24.7 0.094 11.6 9.2 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain CLZ PF16526.5 EON99526.1 - 0.98 9.8 25.5 2.2 8.7 3.3 3.7 1 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels LPP PF04728.13 EON99526.1 - 1 9.8 12.9 5 7.6 0.3 4.1 2 1 2 4 4 4 0 Lipoprotein leucine-zipper BRE1 PF08647.11 EON99526.1 - 1.1 9.3 31.5 3.2 7.9 16.1 2.4 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DUF3287 PF11690.8 EON99526.1 - 1.2 8.9 6.7 4.2 7.1 0.2 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF3287) CHDCT2 PF08074.11 EON99526.1 - 1.3 9.2 10.7 0.25 11.5 4.3 2.0 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain HMMR_C PF15908.5 EON99526.1 - 1.3 9.3 20.2 0.26 11.6 5.3 2.6 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal DUF4201 PF13870.6 EON99526.1 - 1.3 8.7 24.1 2.6 7.7 7.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TFR_dimer PF04253.15 EON99526.1 - 1.5 8.9 16.1 0.11 12.5 1.5 3.1 1 1 2 3 3 3 0 Transferrin receptor-like dimerisation domain TPR_MLP1_2 PF07926.12 EON99526.1 - 1.5 8.9 37.2 3.5 7.7 12.3 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 EON99526.1 - 1.6 6.1 27.7 4.5 4.6 27.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) TANGO2 PF05742.12 EON99526.1 - 1.6 8.7 10.5 1.4 8.9 8.5 1.7 1 1 1 2 2 2 0 Transport and Golgi organisation 2 CENP-H PF05837.12 EON99526.1 - 1.9 8.9 26.1 8.6 6.8 0.5 2.8 1 1 0 2 2 2 0 Centromere protein H (CENP-H) CASP_C PF08172.12 EON99526.1 - 2.4 7.4 21.4 0.62 9.4 2.3 2.1 1 1 1 2 2 2 0 CASP C terminal KELK PF15796.5 EON99526.1 - 2.6 8.6 32.4 0.47 10.9 3.2 3.9 1 1 3 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMF_DNA_bd PF12329.8 EON99526.1 - 3 7.9 37.9 3 7.9 15.3 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF5082 PF16888.5 EON99526.1 - 3.2 8.1 22.2 1.3 9.3 8.6 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Atg14 PF10186.9 EON99526.1 - 3.2 6.7 22.5 2 7.4 14.2 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 EON99526.1 - 3.5 8.1 39.7 3.3 8.2 1.7 4.4 1 1 2 3 3 2 0 Cell division protein ZapB HAP1_N PF04849.13 EON99526.1 - 3.8 6.6 30.3 6.4 5.9 30.3 1.6 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Fib_alpha PF08702.10 EON99526.1 - 3.9 7.6 16.8 5 7.3 3.7 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 EON99526.1 - 5.3 5.5 7.3 5.9 5.3 7.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cep57_MT_bd PF06657.13 EON99526.1 - 6.6 7.3 22.4 0.5 10.8 2.9 3.6 1 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 CorA PF01544.18 EON99526.1 - 6.7 5.9 11.3 3.6 6.8 8.7 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein SHE3 PF17078.5 EON99526.1 - 7.1 6.3 25.7 5.1 6.8 3.8 2.2 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4407 PF14362.6 EON99526.1 - 7.6 5.8 21.7 19 4.5 21.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Sec34 PF04136.15 EON99526.1 - 7.7 6.4 18.1 0.55 10.1 4.5 2.6 1 1 1 2 2 2 0 Sec34-like family Prefoldin_2 PF01920.20 EON99526.1 - 8.4 6.4 35.0 0.57 10.2 2.6 4.2 2 1 2 4 4 4 0 Prefoldin subunit T2SSM PF04612.12 EON99526.1 - 8.9 6.3 15.2 0.75 9.8 1.4 2.9 1 1 1 3 3 3 0 Type II secretion system (T2SS), protein M Trm112p PF03966.16 EON99527.1 - 2.2e-16 60.2 0.1 2.7e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.6 EON99527.1 - 0.048 14.2 0.3 0.079 13.5 0.3 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Pro_isomerase PF00160.21 EON99529.1 - 1.9e-48 164.7 0.3 2.5e-48 164.3 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Porin_3 PF01459.22 EON99530.1 - 1.2e-82 277.4 0.3 1.4e-82 277.2 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin ATP-synt_ab PF00006.25 EON99531.1 - 1.3e-110 368.1 0.0 1.8e-110 367.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EON99531.1 - 3e-48 162.7 0.0 8.8e-48 161.2 0.0 1.9 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EON99531.1 - 1.3e-13 51.3 3.7 3e-13 50.1 3.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Peptidase_M23 PF01551.22 EON99531.1 - 0.2 11.9 1.4 31 4.9 0.1 3.9 4 0 0 4 4 4 0 Peptidase family M23 GLE1 PF07817.13 EON99532.1 - 2.1e-57 194.2 0.0 3e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 GLE1-like protein 6PF2K PF01591.18 EON99533.1 - 2.2e-35 122.0 2.7 3.3e-35 121.4 2.7 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EON99533.1 - 1.7e-20 73.5 0.5 9.1e-20 71.2 0.5 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ZnuA PF01297.17 EON99533.1 - 0.0066 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic Syntaxin-6_N PF09177.11 EON99534.1 - 1.3e-19 70.5 0.3 6.2e-19 68.4 0.0 2.0 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 EON99534.1 - 0.00023 21.1 0.6 0.00054 19.9 0.6 1.7 1 0 0 1 1 1 1 SNARE domain DUF3348 PF11828.8 EON99534.1 - 0.002 17.8 1.0 0.0028 17.4 1.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3348) UPF0242 PF06785.11 EON99534.1 - 0.015 15.4 1.3 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Use1 PF09753.9 EON99534.1 - 0.02 14.7 0.0 0.029 14.1 0.0 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 BLOC1_2 PF10046.9 EON99534.1 - 0.11 12.8 3.3 3.4 8.0 0.3 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.11 EON99534.1 - 0.11 10.4 0.1 0.32 8.9 0.1 1.6 1 1 0 2 2 2 0 Prominin COG2 PF06148.11 EON99534.1 - 0.17 12.0 3.3 4.5 7.4 0.0 3.1 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DegS PF05384.11 EON99534.1 - 0.47 9.9 3.7 0.47 9.9 0.7 2.2 2 1 1 3 3 3 0 Sensor protein DegS Myosin_tail_1 PF01576.19 EON99534.1 - 1 7.1 9.1 1 7.1 0.8 2.0 2 0 0 2 2 2 0 Myosin tail Spc24 PF08286.11 EON99534.1 - 2 8.7 5.3 1.4 9.2 0.2 2.6 2 2 0 2 2 2 0 Spc24 subunit of Ndc80 TBCA PF02970.16 EON99534.1 - 5.1 7.5 8.0 4.9 7.6 2.0 3.0 2 2 1 3 3 3 0 Tubulin binding cofactor A DNA_pol_B PF00136.21 EON99536.1 - 9.1e-151 502.6 1.2 1.3e-150 502.1 1.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EON99536.1 - 1.3e-80 271.1 1.8 1.8e-80 270.6 0.2 2.1 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EON99536.1 - 4.5e-15 55.9 3.9 1.2e-14 54.5 3.9 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 EON99536.1 - 0.005 16.5 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 EON99536.1 - 0.012 14.5 0.1 0.14 11.0 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 EON99536.1 - 0.02 14.9 0.3 0.21 11.6 0.3 2.6 1 1 0 1 1 1 0 RNase_H superfamily DUF2614 PF11023.8 EON99536.1 - 0.11 12.6 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain C1_1 PF00130.22 EON99536.1 - 8.7 6.3 8.9 4.6 7.2 0.6 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Metallophos PF00149.28 EON99537.1 - 6.2e-14 53.0 0.2 9e-14 52.4 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Securin PF04856.13 EON99538.1 - 0.05 13.6 0.2 0.05 13.6 0.2 2.1 2 0 0 2 2 2 0 Securin sister-chromatid separation inhibitor DUF4048 PF13257.6 EON99539.1 - 1.9e-12 47.6 22.9 4e-10 40.0 16.7 3.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4048) GAS PF13851.6 EON99539.1 - 0.037 13.4 1.0 0.056 12.8 1.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Voldacs PF03517.13 EON99540.1 - 1.3e-11 44.8 1.6 2e-11 44.2 1.6 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling BDHCT_assoc PF16204.5 EON99540.1 - 0.14 11.9 0.1 0.19 11.4 0.1 1.1 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein ELFV_dehydrog PF00208.21 EON99541.1 - 2e-83 279.8 2.9 2.5e-83 279.5 2.9 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EON99541.1 - 9.8e-50 167.8 0.0 2.1e-49 166.7 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 EON99541.1 - 0.0022 18.4 0.1 0.0054 17.1 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding ATP-synt_S1 PF05827.12 EON99542.1 - 2.3e-05 24.3 0.1 4.2e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) N-SET PF11764.8 EON99543.1 - 3.1e-56 190.2 1.2 3.1e-56 190.2 1.2 2.9 4 0 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 EON99543.1 - 1.4e-26 91.9 2.6 1.4e-26 91.9 2.6 2.1 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated SET PF00856.28 EON99543.1 - 3.1e-20 73.2 0.2 3.1e-20 73.2 0.2 3.4 3 2 0 3 3 3 1 SET domain RRM_1 PF00076.22 EON99543.1 - 0.016 15.0 0.1 0.55 10.1 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NT-C2 PF10358.9 EON99544.1 - 5.9e-30 103.9 0.0 8.5e-25 87.2 0.0 2.2 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins PCI PF01399.27 EON99545.1 - 2.2e-22 79.6 0.0 8.9e-22 77.6 0.0 2.0 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 EON99545.1 - 3.2e-16 59.1 2.0 7.9e-16 57.9 2.0 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF4336 PF14234.6 EON99546.1 - 1.8e-19 70.1 0.1 5.4e-14 52.1 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) DASH_Spc19 PF08287.11 EON99547.1 - 2.1e-48 164.2 0.2 2.8e-48 163.8 0.2 1.1 1 0 0 1 1 1 1 Spc19 Surfac_D-trimer PF09006.11 EON99547.1 - 0.16 11.9 0.1 15 5.6 0.3 2.4 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Pal1 PF08316.11 EON99550.1 - 9e-49 165.8 0.4 9e-49 165.8 0.4 1.8 2 0 0 2 2 2 1 Pal1 cell morphology protein DLIC PF05783.11 EON99551.1 - 2.8e-12 46.3 0.2 1.5e-09 37.2 0.0 3.2 4 0 0 4 4 4 2 Dynein light intermediate chain (DLIC) NUDIX PF00293.28 EON99552.1 - 1.6e-10 41.1 0.0 5.3e-09 36.2 0.0 2.0 1 1 0 1 1 1 1 NUDIX domain FAD_binding_4 PF01565.23 EON99553.1 - 7.2e-17 61.4 2.8 1.1e-16 60.9 2.8 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 EON99553.1 - 1.3e-10 41.5 1.1 1.3e-08 35.0 1.1 2.5 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase ATP-synt_C PF00137.21 EON99554.1 - 5.4e-28 97.1 35.8 1.5e-17 63.6 12.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ELP6 PF09807.9 EON99554.1 - 0.092 12.2 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Elongation complex protein 6 AXE1 PF05448.12 EON99555.1 - 8.6e-08 31.2 0.0 0.00014 20.6 0.1 2.4 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 EON99555.1 - 2.4e-07 30.7 0.0 1.5e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON99555.1 - 2.3e-06 27.0 0.2 0.00091 18.6 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EON99555.1 - 2e-05 24.4 0.1 3.7e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EON99555.1 - 2.5e-05 23.9 0.0 0.0011 18.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 EON99555.1 - 0.00081 19.4 0.0 0.026 14.5 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2048 PF09752.9 EON99555.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Abhydrolase domain containing 18 UPF0139 PF03669.13 EON99556.1 - 4.6e-10 39.2 0.0 5.9e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Rrp40_N PF18311.1 EON99557.1 - 3e-18 65.5 0.6 3e-18 65.5 0.6 2.0 3 0 0 3 3 3 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 EON99557.1 - 6.5e-16 58.4 0.5 1.1e-15 57.6 0.5 1.4 1 0 0 1 1 1 1 KH domain Glyco_hydro_16 PF00722.21 EON99558.1 - 5.7e-15 55.2 2.3 1e-14 54.4 2.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TaqI_C PF12950.7 EON99558.1 - 0.11 12.6 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain p450 PF00067.22 EON99559.1 - 2.4e-23 82.6 0.0 2.9e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 EON99560.1 - 3.7e-26 92.3 0.1 1.2e-25 90.7 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EON99560.1 - 5.8e-21 73.8 0.0 1e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 EON99560.1 - 0.00011 21.5 0.0 0.08 12.2 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EON99560.1 - 0.0018 17.9 0.0 0.85 9.2 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Beach PF02138.18 EON99561.1 - 4.5e-120 400.2 0.0 6.8e-120 399.6 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EON99561.1 - 2.7e-12 46.7 0.0 6.8e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 EON99561.1 - 0.0002 22.0 0.4 4 8.5 0.0 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF4800 PF16057.5 EON99561.1 - 0.1 11.8 0.7 0.21 10.8 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) PRP38 PF03371.15 EON99562.1 - 2.3e-57 193.7 0.0 2.7e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Ribosomal_S28e PF01200.18 EON99563.1 - 1.7e-31 108.0 1.7 1.9e-31 107.8 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Isy1 PF06246.12 EON99564.1 - 2.1e-91 306.0 1.4 2.5e-91 305.8 1.4 1.0 1 0 0 1 1 1 1 Isy1-like splicing family NIPSNAP PF07978.13 EON99565.1 - 3.6e-29 101.0 0.1 6e-17 61.7 0.0 2.8 2 0 0 2 2 2 2 NIPSNAP Pirin PF02678.16 EON99566.1 - 7.6e-25 87.0 0.5 2e-24 85.6 0.5 1.7 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 EON99566.1 - 0.00091 18.9 2.8 0.04 13.6 0.9 3.0 2 1 0 2 2 2 2 Cupin domain Pirin_C_2 PF17954.1 EON99566.1 - 0.0062 16.7 0.0 0.022 14.9 0.0 2.0 2 0 0 2 2 2 1 Quercetinase C-terminal cupin domain MmgE_PrpD PF03972.14 EON99567.1 - 2.2e-147 491.2 0.0 2.5e-147 491.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF4718 PF15842.5 EON99571.1 - 0.062 13.1 0.3 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) RNA_pol_3_Rpc31 PF11705.8 EON99571.1 - 1.2 9.4 11.6 1.6 8.9 11.4 1.3 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TAL_FSA PF00923.19 EON99572.1 - 3e-93 312.3 1.5 3.6e-93 312.0 1.5 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase CAP PF00188.26 EON99573.1 - 4.3e-14 53.4 3.5 6.1e-14 52.9 3.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TRI12 PF06609.13 EON99574.1 - 4.4e-56 190.5 19.0 1.6e-54 185.4 18.5 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EON99574.1 - 8.9e-10 38.0 43.0 1.3e-09 37.4 38.5 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2976 PF11190.8 EON99574.1 - 0.062 13.1 1.0 1 9.2 0.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) IBR PF01485.21 EON99575.1 - 0.04 14.1 4.0 0.097 12.9 4.0 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain MethyltransfD12 PF02086.15 EON99575.1 - 0.13 12.0 6.5 0.025 14.3 2.0 1.9 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase PAD_M PF08527.10 EON99575.1 - 0.23 11.1 1.7 0.83 9.3 0.2 2.2 2 1 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain HTH_12 PF08461.10 EON99575.1 - 0.42 10.6 7.8 0.049 13.6 1.4 2.8 2 1 1 3 3 3 0 Ribonuclease R winged-helix domain MMR_HSR1 PF01926.23 EON99576.1 - 6e-12 45.7 0.0 1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EON99576.1 - 0.0095 15.5 0.1 0.045 13.3 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 EON99576.1 - 0.011 15.2 0.1 0.047 13.1 0.0 1.8 1 1 1 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 EON99576.1 - 0.014 15.5 0.1 0.43 10.6 0.0 2.3 2 0 0 2 2 2 0 Dynamin family AAA_16 PF13191.6 EON99576.1 - 0.038 14.4 0.5 1.5 9.1 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EON99576.1 - 0.098 12.4 0.5 2.2 8.1 0.0 2.3 1 1 1 2 2 2 0 P-loop containing region of AAA domain DUF2992 PF11208.8 EON99576.1 - 0.11 12.8 0.8 0.21 11.9 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2992) AAA_22 PF13401.6 EON99576.1 - 0.14 12.4 0.0 4.1 7.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain IIGP PF05049.13 EON99576.1 - 0.24 10.4 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.6 EON99576.1 - 0.27 11.8 1.1 0.58 10.7 0.3 1.9 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EON99576.1 - 0.62 10.0 7.2 1.6 8.6 0.1 3.4 3 1 1 4 4 4 0 RsgA GTPase HSP70 PF00012.20 EON99577.1 - 4e-77 259.8 0.8 4e-77 259.8 0.8 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EON99577.1 - 1.4e-07 30.7 0.1 2.2e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein DUF3221 PF11518.8 EON99577.1 - 0.012 16.0 1.9 0.03 14.7 1.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) MPP6 PF10175.9 EON99577.1 - 0.029 14.9 2.3 1.7 9.2 0.1 2.6 2 0 0 2 2 2 0 M-phase phosphoprotein 6 PBP1_TM PF14812.6 EON99577.1 - 0.42 11.0 4.0 1.1 9.6 4.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 EON99577.1 - 0.81 10.1 6.2 2.1 8.8 6.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Gar1 PF04410.14 EON99577.1 - 1.1 9.0 5.8 3.2 7.5 5.8 1.7 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region NOA36 PF06524.12 EON99577.1 - 6.1 6.1 5.6 10 5.3 5.6 1.2 1 0 0 1 1 1 0 NOA36 protein SH3_1 PF00018.28 EON99578.1 - 4.9e-09 35.7 0.1 8.8e-09 34.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EON99578.1 - 1.4e-06 28.1 0.0 2.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EON99578.1 - 1.1e-05 25.0 0.0 2.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Transp_cyt_pur PF02133.15 EON99579.1 - 2.6e-46 158.3 22.2 3.3e-46 158.0 22.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RRM_1 PF00076.22 EON99580.1 - 4.2e-14 52.1 0.0 6.4e-13 48.3 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EON99580.1 - 0.0051 16.9 0.0 0.018 15.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif YjeF_N PF03853.15 EON99581.1 - 1.6e-24 86.7 0.0 1.9e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus RNase_H2_suC PF08615.11 EON99581.1 - 0.16 12.2 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SL4P PF17618.2 EON99581.1 - 0.19 11.8 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein S1-P1_nuclease PF02265.16 EON99582.1 - 2.1e-74 250.5 0.0 2.4e-74 250.4 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease STAT_alpha PF01017.20 EON99582.1 - 0.17 11.8 0.1 0.24 11.3 0.1 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain SNase PF00565.17 EON99583.1 - 9.2e-73 241.6 1.9 1.5e-22 80.1 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EON99583.1 - 1.9e-23 82.8 0.0 3.7e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 EON99583.1 - 3.4e-06 26.5 0.6 6.1e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) Rpp20 PF12328.8 EON99584.1 - 9.6e-25 87.1 0.0 1.2e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EON99584.1 - 3.2e-07 30.1 0.0 4.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Alba RNR_inhib PF08591.10 EON99585.1 - 1.2e-30 107.0 0.0 2.5e-30 105.9 0.0 1.6 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor Pectate_lyase_3 PF12708.7 EON99586.1 - 2.1e-88 295.7 12.9 4.6e-80 268.5 3.3 3.0 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EON99586.1 - 3.1e-07 30.0 2.0 0.005 16.5 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase CNH PF00780.22 EON99587.1 - 5.9e-65 219.6 0.0 9.9e-65 218.9 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EON99587.1 - 8.9e-32 110.8 0.3 1.6e-31 110.0 0.3 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 EON99587.1 - 1.3e-12 47.9 0.0 8.4e-12 45.4 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EON99587.1 - 0.00017 22.0 0.0 0.0031 18.0 0.0 2.9 3 0 0 3 3 3 1 PH domain PH_16 PF17838.1 EON99587.1 - 0.0031 17.4 0.0 2 8.3 0.0 2.8 2 0 0 2 2 2 2 PH domain PH_13 PF16652.5 EON99587.1 - 0.12 12.2 0.0 0.65 9.8 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Amidase PF01425.21 EON99588.1 - 7.8e-109 364.6 0.0 1.4e-108 363.8 0.0 1.3 1 0 0 1 1 1 1 Amidase DUF3693 PF12472.8 EON99588.1 - 0.0034 17.0 0.0 0.0089 15.7 0.0 1.7 1 0 0 1 1 1 1 Phage related protein Big_3_5 PF16640.5 EON99588.1 - 0.21 11.8 3.7 0.43 10.8 3.7 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) DUF4360 PF14273.6 EON99589.1 - 1.4e-68 230.2 7.2 1.6e-68 230.1 7.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) tRNA-synt_2 PF00152.20 EON99590.1 - 7.4e-33 114.0 0.0 8.2e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) TRAM_LAG1_CLN8 PF03798.16 EON99591.1 - 2.8e-42 144.7 12.0 2.8e-42 144.7 12.0 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EON99591.1 - 3.1e-21 74.8 0.6 3.1e-21 74.8 0.6 1.9 2 0 0 2 2 2 1 TRAM1-like protein Pkinase PF00069.25 EON99592.1 - 2.4e-26 92.7 0.0 3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON99592.1 - 6.5e-14 51.8 0.0 9.1e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EON99592.1 - 3.7e-09 35.9 0.3 6.3e-09 35.1 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EON99592.1 - 0.00017 21.6 0.0 0.0014 18.6 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Citrate_synt PF00285.21 EON99593.1 - 3.8e-102 342.0 0.0 4.7e-102 341.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Polysacc_lyase PF14099.6 EON99594.1 - 7.8e-52 176.2 7.8 9.1e-52 176.0 7.8 1.0 1 0 0 1 1 1 1 Polysaccharide lyase Med12-LCEWAV PF12145.8 EON99595.1 - 0.0054 15.6 0.2 0.13 11.1 0.0 2.5 1 1 0 2 2 2 2 Eukaryotic Mediator 12 subunit domain Hormone_2 PF00123.20 EON99596.1 - 0.14 12.1 0.0 0.41 10.6 0.0 1.8 2 0 0 2 2 2 0 Peptide hormone CFEM PF05730.11 EON99597.1 - 0.0011 19.0 2.0 0.0011 19.0 2.0 3.1 2 0 0 2 2 2 1 CFEM domain CNH PF00780.22 EON99598.1 - 3.3e-80 269.6 0.0 1.2e-79 267.7 0.0 1.8 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 EON99598.1 - 2.7e-43 147.3 0.0 5.1e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EON99598.1 - 1.2e-37 129.9 0.8 3e-37 128.6 0.3 1.9 2 0 0 2 2 2 1 RhoGEF domain DEP PF00610.21 EON99598.1 - 6.8e-15 54.9 0.0 1.5e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 EON99598.1 - 0.0082 16.0 0.4 0.039 13.8 0.0 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain Mannitol_dh_C PF08125.13 EON99599.1 - 4.8e-77 258.8 0.0 8.2e-77 258.0 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EON99599.1 - 8.8e-45 152.5 0.0 1.5e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain Kelch_5 PF13854.6 EON99601.1 - 4.5e-10 39.3 7.7 3.8e-06 26.7 0.1 4.9 4 0 0 4 4 4 2 Kelch motif Adeno_E3_CR2 PF02439.15 EON99601.1 - 0.0022 17.7 0.2 0.0042 16.8 0.2 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Gly-zipper_Omp PF13488.6 EON99601.1 - 0.0024 17.8 7.1 0.0024 17.8 7.1 2.0 2 0 0 2 2 2 1 Glycine zipper Gly-zipper_YMGG PF13441.6 EON99601.1 - 0.011 15.4 4.7 0.011 15.4 4.7 1.9 2 0 0 2 2 2 0 YMGG-like Gly-zipper Syndecan PF01034.20 EON99601.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 EON99601.1 - 0.018 15.9 0.0 0.045 14.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Beta-APP PF03494.13 EON99601.1 - 0.02 14.7 8.7 0.067 13.0 8.7 1.9 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Herpes_gE PF02480.16 EON99601.1 - 0.093 11.5 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM51 PF15345.6 EON99601.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 YajC PF02699.15 EON99601.1 - 0.71 9.8 1.9 0.78 9.7 0.8 1.6 1 1 0 1 1 1 0 Preprotein translocase subunit Rick_17kDa_Anti PF05433.15 EON99601.1 - 1.5 8.7 14.3 0.028 14.3 6.9 1.9 2 0 0 2 2 1 0 Glycine zipper 2TM domain Kelch_2 PF07646.15 EON99601.1 - 4 7.6 5.8 8.1 6.6 0.1 3.9 4 1 0 4 4 4 0 Kelch motif SKG6 PF08693.10 EON99601.1 - 5.1 6.6 11.3 0.036 13.5 1.3 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain UQ_con PF00179.26 EON99602.1 - 3.6e-37 127.1 0.0 4.2e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EON99602.1 - 0.00049 19.8 0.0 0.00068 19.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EON99602.1 - 0.0093 15.8 0.1 0.019 14.9 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 EON99602.1 - 0.055 13.8 0.2 0.074 13.3 0.2 1.5 1 1 0 1 1 1 0 RWD domain Bax1-I PF01027.20 EON99603.1 - 7e-54 182.8 25.0 8e-54 182.6 25.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF5504 PF17608.2 EON99603.1 - 0.32 11.1 9.8 0.08 13.1 5.7 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5504) SIP1 PF04938.12 EON99606.1 - 4e-06 26.7 0.0 0.00058 19.6 0.0 3.0 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) CPSase_L_D3 PF02787.19 EON99606.1 - 0.19 12.1 0.0 0.65 10.4 0.0 1.9 1 1 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 2OG-FeII_Oxy_2 PF13532.6 EON99607.1 - 2.1e-19 70.5 0.0 4.9e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily C1_2 PF03107.16 EON99607.1 - 6.1 7.2 16.0 5 7.5 5.3 2.7 2 0 0 2 2 2 0 C1 domain Glyco_hydro_3_C PF01915.22 EON99608.1 - 6.4e-39 134.0 0.6 1.1e-38 133.3 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EON99608.1 - 4.2e-32 111.8 0.0 6.6e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EON99608.1 - 1.8e-05 24.7 0.0 4.2e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Shadoo PF14999.6 EON99608.1 - 0.018 15.1 3.9 0.18 11.9 1.3 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective NTP_transf_3 PF12804.7 EON99608.1 - 0.083 13.2 1.4 0.19 12.1 0.3 2.2 3 0 0 3 3 3 0 MobA-like NTP transferase domain DLH PF01738.18 EON99609.1 - 3.6e-12 46.3 0.0 5.1e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Phosducin PF02114.16 EON99612.1 - 5.2e-14 51.8 0.0 8.2e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 EON99612.1 - 0.0084 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Fasciclin PF02469.22 EON99614.1 - 2.7e-42 144.0 0.1 1.4e-22 80.3 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain RabGAP-TBC PF00566.18 EON99615.1 - 8.9e-47 159.5 0.0 1.4e-46 158.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 EON99615.1 - 4.9e-08 32.3 0.3 0.014 15.2 0.3 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EON99615.1 - 2.8e-07 29.6 0.7 0.054 13.1 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EON99615.1 - 0.00012 22.5 0.2 0.0014 19.1 0.2 2.7 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EON99615.1 - 0.0084 15.6 0.2 0.14 11.7 0.2 2.6 2 0 0 2 2 2 1 EF hand GRAM PF02893.20 EON99615.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 GRAM domain Asp PF00026.23 EON99616.1 - 2.5e-38 132.3 0.0 3.5e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EON99616.1 - 1.7e-11 44.7 0.1 1.9e-10 41.3 0.0 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Carboxyl_trans PF01039.22 EON99617.1 - 3.2e-136 454.8 0.0 3.9e-136 454.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EON99617.1 - 0.0036 16.8 0.2 2.2 7.7 0.0 2.5 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Sugar_tr PF00083.24 EON99618.1 - 3.4e-37 128.4 13.0 4.1e-37 128.1 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON99618.1 - 5.5e-05 22.3 41.4 0.0006 18.8 13.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Collectrin PF16959.5 EON99618.1 - 0.097 12.4 0.2 1.3 8.7 0.1 2.2 2 0 0 2 2 2 0 Renal amino acid transporter Asp PF00026.23 EON99619.1 - 2.2e-61 208.0 7.1 2.7e-61 207.7 7.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EON99619.1 - 1.3e-18 67.9 1.3 5.4e-18 65.8 0.2 2.6 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EON99619.1 - 0.0023 18.5 3.1 1.6 9.4 0.2 3.7 2 2 1 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EON99619.1 - 0.0024 18.4 0.8 6.9 7.3 0.1 3.8 2 2 0 2 2 2 2 gag-polyprotein putative aspartyl protease WD40 PF00400.32 EON99620.1 - 8.1e-19 67.6 4.1 0.00065 20.5 0.0 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON99620.1 - 5.2e-07 29.9 0.0 2.4 8.5 0.0 4.6 3 1 0 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain adh_short_C2 PF13561.6 EON99621.1 - 6.5e-57 192.8 0.0 7.6e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON99621.1 - 1.3e-42 145.5 0.2 1.5e-42 145.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON99621.1 - 5.3e-11 42.8 1.1 7.9e-11 42.2 1.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EON99621.1 - 3.4e-05 23.8 0.2 6.4e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 EON99621.1 - 0.002 18.8 0.0 0.0039 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ChuX_HutX PF06228.13 EON99621.1 - 0.0052 16.5 0.1 1.1 9.0 0.1 2.3 1 1 1 2 2 2 2 Haem utilisation ChuX/HutX Methyltransf_12 PF08242.12 EON99621.1 - 0.022 15.5 0.0 0.042 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.15 EON99621.1 - 0.029 13.5 0.1 0.048 12.8 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 EON99621.1 - 0.053 13.1 0.1 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RecC_C PF17946.1 EON99621.1 - 0.088 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 RecC C-terminal domain 3Beta_HSD PF01073.19 EON99621.1 - 0.14 11.2 0.1 0.26 10.3 0.1 1.5 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_S27e PF01667.17 EON99622.1 - 3.5e-28 97.1 7.5 4.2e-28 96.8 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 EON99622.1 - 0.14 11.7 3.5 0.19 11.2 3.5 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zf-C2HC5 PF06221.13 EON99622.1 - 1.2 9.2 7.0 2.7 8.0 4.3 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Carn_acyltransf PF00755.20 EON99623.1 - 6.1e-99 332.3 0.0 8.4e-99 331.8 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PP-binding PF00550.25 EON99623.1 - 0.0039 17.5 0.7 0.01 16.2 0.2 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site DUF982 PF06169.12 EON99623.1 - 0.0055 16.7 2.2 0.035 14.2 0.3 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF982) Pyridoxal_deC PF00282.19 EON99624.1 - 8.1e-61 205.8 0.0 1.2e-60 205.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EON99624.1 - 0.00045 19.3 0.0 0.00091 18.3 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V NUDIX PF00293.28 EON99625.1 - 1.4e-08 34.8 0.1 2.9e-08 33.8 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain Nse4_C PF08743.10 EON99626.1 - 3.2e-18 65.8 0.0 8.5e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EON99626.1 - 3.8e-16 58.9 1.4 6.3e-16 58.2 0.0 2.1 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE TssO PF17561.2 EON99626.1 - 0.034 14.2 1.1 0.077 13.1 1.1 1.6 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF2115 PF09888.9 EON99626.1 - 0.038 14.5 1.3 3.2 8.3 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) DUF3037 PF11236.8 EON99626.1 - 0.11 13.0 2.6 2.8 8.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) zf-C4H2 PF10146.9 EON99626.1 - 0.33 11.2 5.2 2.7 8.2 0.2 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein Apolipoprotein PF01442.18 EON99626.1 - 0.6 10.0 7.9 1.5 8.7 0.8 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Focal_AT PF03623.13 EON99626.1 - 1.2 9.2 5.0 0.46 10.5 0.9 2.0 2 0 0 2 2 2 0 Focal adhesion targeting region YtxH PF12732.7 EON99626.1 - 2 9.0 3.6 13 6.4 0.4 2.4 2 0 0 2 2 2 0 YtxH-like protein zf-P11 PF03854.14 EON99627.1 - 0.0077 15.9 2.1 0.012 15.3 2.1 1.2 1 0 0 1 1 1 1 P-11 zinc finger RTA1 PF04479.13 EON99628.1 - 1.3e-78 263.4 4.5 1.3e-78 263.4 4.5 1.4 2 0 0 2 2 2 1 RTA1 like protein PQ-loop PF04193.14 EON99632.1 - 1.3e-39 133.7 6.8 4.6e-20 71.1 0.6 3.1 2 1 0 2 2 2 2 PQ loop repeat PgaD PF13994.6 EON99632.1 - 0.16 12.0 0.1 0.42 10.7 0.1 1.7 1 0 0 1 1 1 0 PgaD-like protein WSC PF01822.19 EON99633.1 - 1.2e-21 76.7 70.0 1.4e-10 41.2 7.2 5.4 6 0 0 6 6 6 4 WSC domain ADH_zinc_N PF00107.26 EON99634.1 - 1.4e-14 54.2 0.0 2.4e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON99634.1 - 0.00011 22.0 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 EON99635.1 - 3.1e-53 180.7 0.1 5.9e-53 179.8 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON99635.1 - 1.2e-37 129.3 0.3 1.8e-37 128.7 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON99635.1 - 2.1e-11 44.0 0.2 2.1e-11 44.0 0.2 1.4 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 EON99635.1 - 0.069 12.5 0.1 0.31 10.4 0.1 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EON99636.1 - 9.3e-20 70.9 0.0 1.2e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON99636.1 - 3e-14 53.2 0.0 4.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON99636.1 - 0.009 15.9 0.0 0.027 14.4 0.0 1.8 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EON99636.1 - 0.031 13.4 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 EON99636.1 - 0.038 13.4 0.0 0.069 12.6 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EON99636.1 - 0.04 13.8 0.0 0.052 13.4 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Thioredox_DsbH PF03190.15 EON99637.1 - 1.5e-62 210.4 0.0 2.5e-62 209.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 EON99637.1 - 1.7e-06 28.1 0.0 3.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_76 PF03663.14 EON99637.1 - 0.00023 20.8 0.3 0.0014 18.2 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Glyco_hydro_9 PF00759.19 EON99637.1 - 0.00026 20.6 0.9 0.0005 19.6 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 GlcNAc_2-epim PF07221.11 EON99637.1 - 0.021 14.1 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Histone_HNS PF00816.21 EON99637.1 - 0.072 13.9 0.5 10 7.0 0.0 2.6 2 0 0 2 2 2 0 H-NS histone family Thioredoxin_2 PF13098.6 EON99637.1 - 0.11 13.0 0.0 0.46 11.0 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain STAS_2 PF13466.6 EON99637.1 - 0.13 12.6 0.3 4.8 7.6 0.0 2.9 2 1 0 2 2 2 0 STAS domain Med12 PF09497.10 EON99638.1 - 2.3e-28 98.3 0.3 4.2e-28 97.4 0.3 1.5 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 ER-remodelling PF14755.6 EON99638.1 - 0.02 15.2 5.6 0.044 14.1 5.6 1.5 1 0 0 1 1 1 0 Intracellular membrane remodeller bVLRF1 PF18826.1 EON99639.1 - 1.2e-62 210.2 0.0 1.2e-62 210.2 0.0 1.8 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 EON99639.1 - 3.6e-05 24.0 0.1 6.8e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EON99639.1 - 0.021 15.2 0.3 0.048 14.1 0.3 1.6 1 0 0 1 1 1 0 Ankyrin repeat DUF4674 PF15719.5 EON99640.1 - 2.4 8.2 0.0 2.4 8.2 0.0 3.7 4 1 0 4 4 4 0 Domain of unknown function (DUF4674) Tropomyosin_1 PF12718.7 EON99641.1 - 6.2e-05 23.2 4.2 6.2e-05 23.2 4.2 2.7 1 1 1 2 2 2 1 Tropomyosin like DUF4094 PF13334.6 EON99641.1 - 0.00077 19.8 1.0 1.5 9.3 0.0 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF4094) LPP PF04728.13 EON99641.1 - 0.0083 16.5 3.9 0.4 11.1 0.0 3.7 2 1 1 3 3 3 1 Lipoprotein leucine-zipper Pox_A_type_inc PF04508.12 EON99641.1 - 0.012 15.5 1.7 0.049 13.5 0.1 2.9 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat TSC22 PF01166.18 EON99641.1 - 0.026 14.8 7.2 0.91 9.9 0.3 3.3 2 1 1 3 3 3 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.9 EON99641.1 - 0.045 13.8 17.7 0.045 13.8 5.8 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fmp27_WPPW PF10359.9 EON99641.1 - 0.055 12.3 9.3 0.078 11.8 9.3 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain BLOC1_2 PF10046.9 EON99641.1 - 0.058 13.7 12.4 4.3 7.7 4.7 3.7 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GIT_CC PF16559.5 EON99641.1 - 0.1 12.5 3.7 0.15 12.0 0.5 2.8 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Spc7 PF08317.11 EON99641.1 - 0.15 10.9 22.6 0.39 9.6 8.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein BST2 PF16716.5 EON99641.1 - 0.26 11.9 21.0 0.82 10.3 3.6 3.9 1 1 2 4 4 4 0 Bone marrow stromal antigen 2 FAM76 PF16046.5 EON99641.1 - 0.37 10.1 15.4 1.1 8.5 2.6 2.1 1 1 1 2 2 2 0 FAM76 protein MIF4G_like_2 PF09090.11 EON99641.1 - 0.38 10.2 14.0 0.031 13.8 3.3 2.4 1 1 2 3 3 3 0 MIF4G like TPX2 PF06886.11 EON99641.1 - 0.44 10.8 8.5 8.1 6.8 3.9 2.6 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Atg14 PF10186.9 EON99641.1 - 1.4 7.9 19.1 6.8 5.7 10.6 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 NPV_P10 PF05531.12 EON99641.1 - 1.7 9.2 10.3 3.2 8.3 1.2 3.6 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.19 EON99641.1 - 2.5 5.9 9.0 3.7 5.3 9.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fungal_TACC PF12709.7 EON99641.1 - 2.7 8.5 12.7 12 6.4 0.2 3.4 2 1 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Sec2p PF06428.11 EON99641.1 - 3.4 7.7 19.8 3.7 7.6 4.2 3.7 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p bZIP_1 PF00170.21 EON99641.1 - 6.1 7.0 14.3 4.6 7.4 3.9 3.9 2 1 2 4 4 4 0 bZIP transcription factor FUSC PF04632.12 EON99641.1 - 6.3 5.2 8.3 14 4.0 7.6 1.8 1 1 0 1 1 1 0 Fusaric acid resistance protein family SlyX PF04102.12 EON99641.1 - 6.7 7.4 14.5 23 5.7 0.8 4.1 1 1 2 3 3 3 0 SlyX TMPIT PF07851.13 EON99641.1 - 6.8 5.8 11.2 2.7 7.2 0.8 2.2 1 1 0 2 2 2 0 TMPIT-like protein DUF4407 PF14362.6 EON99641.1 - 8.8 5.6 18.6 2e+03 -2.1 18.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 EON99642.1 - 2.4e-65 220.6 0.0 2.8e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON99642.1 - 1.2e-31 109.9 0.0 1.6e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EON99642.1 - 3.9e-06 26.4 0.0 5.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EON99642.1 - 0.0071 16.3 0.0 0.021 14.8 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EON99642.1 - 0.035 13.2 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EON99642.1 - 0.064 12.2 0.0 0.082 11.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain YABBY PF04690.13 EON99643.1 - 0.75 10.3 4.2 1.1 9.9 4.2 1.2 1 0 0 1 1 1 0 YABBY protein ICL PF00463.21 EON99644.1 - 7.5e-200 664.9 0.1 8.6e-200 664.7 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Arnt_C PF18583.1 EON99644.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain SH3_1 PF00018.28 EON99645.1 - 1.3e-13 50.4 0.0 1.9e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EON99645.1 - 1.6e-09 37.4 0.0 2.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EON99645.1 - 1.5e-06 27.7 0.0 2.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Sec66 PF09802.9 EON99645.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 Septin PF00735.18 EON99646.1 - 1.8e-102 342.4 0.2 4.9e-102 341.0 0.0 1.8 2 1 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EON99646.1 - 0.0011 19.0 0.0 0.0029 17.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EON99646.1 - 0.092 12.3 0.2 0.53 9.8 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EON99646.1 - 0.24 11.4 3.9 1.9 8.5 0.0 3.1 2 1 1 3 3 3 0 Dynamin family EB1 PF03271.17 EON99646.1 - 0.28 11.4 2.2 5.9 7.2 1.1 2.6 2 0 0 2 2 2 0 EB1-like C-terminal motif Metallophos PF00149.28 EON99647.1 - 1.4e-10 42.0 0.1 5.7e-10 40.0 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EON99647.1 - 2.9e-07 30.8 0.2 1.1e-06 29.0 0.2 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.16 EON99648.1 - 4.4e-18 65.3 10.6 3.6e-11 42.6 5.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_4_2 PF04020.13 EON99648.1 - 0.0016 19.1 8.0 0.0045 17.6 8.0 1.7 1 0 0 1 1 1 1 Mycobacterial 4 TMS phage holin, superfamily IV MKRN1_C PF15815.5 EON99648.1 - 0.21 12.0 1.6 0.27 11.6 0.5 1.7 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase makorin-1, C-terminal DUF4064 PF13273.6 EON99648.1 - 0.57 10.5 8.4 0.24 11.7 4.5 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF4064) Trp_DMAT PF11991.8 EON99649.1 - 1.7e-98 330.4 0.0 2.4e-98 329.9 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Abhydrolase_6 PF12697.7 EON99650.1 - 0.0024 18.5 0.0 0.003 18.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON99650.1 - 0.11 11.7 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DEAD_2 PF06733.15 EON99652.1 - 5.6e-56 188.9 0.1 1.2e-55 187.8 0.1 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 EON99652.1 - 1e-43 149.5 0.0 4e-43 147.5 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain HBB PF06777.11 EON99652.1 - 7.6e-25 87.7 1.5 3.9e-19 69.1 0.0 3.4 3 0 0 3 3 3 3 Helical and beta-bridge domain ResIII PF04851.15 EON99652.1 - 7.2e-05 22.9 0.1 0.0015 18.6 0.1 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EON99652.1 - 0.0033 16.2 0.5 0.12 11.1 0.5 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EON99652.1 - 0.016 15.0 0.1 7.1 6.4 0.0 2.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase DUF2075 PF09848.9 EON99652.1 - 0.076 12.2 0.0 7.4 5.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EON99652.1 - 0.17 11.3 0.1 9.3 5.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Exo_endo_phos PF03372.23 EON99653.1 - 2.6e-06 27.2 0.0 1.1e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF695 PF05117.12 EON99653.1 - 0.012 15.7 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF695) DDOST_48kD PF03345.14 EON99654.1 - 5.6e-160 532.7 0.0 6.4e-160 532.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Glyco_hydro_18 PF00704.28 EON99655.1 - 1.4e-20 74.2 6.5 2.5e-20 73.5 6.5 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EON99655.1 - 1e-05 25.5 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 LysM domain Acyl-CoA_dh_1 PF00441.24 EON99656.1 - 3.6e-41 140.9 1.0 7.7e-41 139.8 1.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON99656.1 - 1.8e-31 109.1 0.4 3.7e-31 108.1 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON99656.1 - 4.8e-27 94.0 0.2 9.1e-27 93.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON99656.1 - 4.3e-12 46.5 0.1 9.3e-12 45.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EON99656.1 - 0.00012 21.9 0.1 0.0003 20.5 0.1 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AMP-binding PF00501.28 EON99657.1 - 1.9e-37 128.9 0.1 2.3e-37 128.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON99657.1 - 1.6e-16 61.0 0.2 3.4e-16 60.0 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pet191_N PF10203.9 EON99658.1 - 5.4e-28 97.1 4.9 7.1e-28 96.7 4.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 EON99658.1 - 0.095 12.7 4.6 2.8 8.0 0.3 2.4 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Glyco_trans_2_3 PF13632.6 EON99659.1 - 8.6e-51 172.7 7.3 3e-50 170.9 7.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EON99659.1 - 4.2e-06 26.7 0.0 1.5e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EON99659.1 - 0.0045 16.5 0.0 0.0093 15.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 PI3Ka PF00613.20 EON99660.1 - 8.5e-62 207.8 1.9 8.5e-62 207.8 1.9 1.6 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EON99660.1 - 2.3e-46 158.7 0.1 2.3e-30 106.2 0.1 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EON99660.1 - 1.2e-35 122.4 0.0 2.5e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Metallophos PF00149.28 EON99661.1 - 1e-09 39.2 1.4 2.9e-09 37.8 1.4 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 EON99661.1 - 0.0027 17.9 0.1 0.036 14.3 0.0 2.4 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain B12-binding PF02310.19 EON99661.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Sod_Cu PF00080.20 EON99662.1 - 8.2e-47 158.9 5.6 9.6e-47 158.7 5.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) ATP12 PF07542.11 EON99663.1 - 1.4e-42 144.8 1.1 1.9e-42 144.4 0.1 1.8 2 0 0 2 2 2 1 ATP12 chaperone protein Mob1_phocein PF03637.17 EON99664.1 - 6.5e-41 140.2 0.0 1.4e-40 139.1 0.0 1.5 1 1 0 1 1 1 1 Mob1/phocein family GDC-P PF02347.16 EON99665.1 - 1e-171 571.5 0.0 1.3e-156 521.8 0.0 2.7 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 EON99665.1 - 2.8e-06 26.8 0.0 4.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DHR10 PF18595.1 EON99666.1 - 0.0098 15.9 2.4 0.0098 15.9 2.4 5.9 6 0 0 6 6 6 3 Designed helical repeat protein 10 domain JIP_LZII PF16471.5 EON99666.1 - 0.28 11.4 23.4 0.055 13.6 1.2 5.9 5 1 0 5 5 5 0 JNK-interacting protein leucine zipper II Lipoprotein_20 PF13942.6 EON99666.1 - 1.8 8.5 21.7 0.12 12.3 8.7 3.4 3 0 0 3 3 3 0 YfhG lipoprotein DUF4200 PF13863.6 EON99666.1 - 1.9 8.9 54.5 0.24 11.8 12.3 5.5 4 1 1 5 5 5 0 Domain of unknown function (DUF4200) DUF1664 PF07889.12 EON99666.1 - 2 8.5 24.0 1.6 8.8 2.0 4.9 2 2 0 4 4 4 0 Protein of unknown function (DUF1664) ZapD PF07072.11 EON99666.1 - 4.9 6.8 15.8 0.75 9.5 2.4 4.1 3 1 1 4 4 4 0 Cell division protein Peptidase_S8 PF00082.22 EON99667.1 - 2.3e-33 115.8 8.9 4.9e-33 114.7 8.9 1.5 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EON99667.1 - 2.3e-22 79.4 1.2 6.7e-22 78.0 1.2 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 Zn_clus PF00172.18 EON99668.1 - 2.7e-05 24.2 4.5 4.5e-05 23.5 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.26 EON99669.1 - 5.7e-22 78.1 0.1 8.9e-22 77.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EON99669.1 - 1.5e-09 37.6 2.6 7e-09 35.5 2.6 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EON99669.1 - 3.1e-07 31.5 0.1 5.1e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EON99669.1 - 2.9e-05 23.5 0.4 5.5e-05 22.6 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 EON99669.1 - 0.00024 20.5 0.4 0.00074 18.8 0.3 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON99669.1 - 0.017 14.4 0.1 0.027 13.7 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EON99669.1 - 0.046 13.1 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 EON99669.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.5 2 0 0 2 2 2 0 ThiF family p450 PF00067.22 EON99670.1 - 6e-41 140.7 0.0 2.7e-38 131.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF4904 PF16247.5 EON99670.1 - 0.049 13.4 0.1 2.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4904) FAD_binding_4 PF01565.23 EON99671.1 - 9e-13 48.2 5.1 2.1e-12 47.0 1.8 2.6 1 1 1 2 2 2 2 FAD binding domain ABC_tran PF00005.27 EON99672.1 - 7.3e-50 169.1 0.0 5.3e-27 95.0 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EON99672.1 - 9.4e-16 58.5 7.2 1.2e-05 25.3 1.9 4.6 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON99672.1 - 3.1e-13 49.7 0.1 6e-05 22.6 0.0 4.0 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 EON99672.1 - 9.6e-10 38.2 0.2 1.9e-09 37.2 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 EON99672.1 - 1.8e-08 35.2 2.9 0.0002 21.9 0.1 2.8 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 EON99672.1 - 4.1e-07 30.1 0.0 0.0039 17.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EON99672.1 - 7e-07 28.9 1.1 0.0072 16.1 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EON99672.1 - 1.1e-06 28.6 0.1 0.013 15.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 EON99672.1 - 0.00018 21.3 0.0 0.14 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EON99672.1 - 0.00019 21.7 0.1 0.58 10.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EON99672.1 - 0.00041 20.6 0.0 0.014 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EON99672.1 - 0.001 19.6 0.0 0.46 11.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EON99672.1 - 0.0017 17.4 0.5 0.85 8.6 0.0 2.9 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EON99672.1 - 0.0031 17.6 0.0 0.59 10.2 0.0 2.8 2 1 0 2 2 2 1 Dynamin family SbcCD_C PF13558.6 EON99672.1 - 0.0033 17.6 0.0 1.9 8.8 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EON99672.1 - 0.0039 17.3 0.0 2.7 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EON99672.1 - 0.004 17.5 0.1 5.6 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 EON99672.1 - 0.005 16.6 0.6 0.55 9.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EON99672.1 - 0.0054 16.7 0.1 2.9 7.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.9 EON99672.1 - 0.012 15.4 0.1 0.85 9.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 EON99672.1 - 0.013 15.9 0.1 5.8 7.3 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EON99672.1 - 0.015 15.0 0.7 2.3 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 EON99672.1 - 0.024 13.3 0.0 5.6 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain HEAT_2 PF13646.6 EON99672.1 - 0.034 14.5 3.0 7.5 7.0 0.0 4.5 4 1 0 5 5 4 0 HEAT repeats Roc PF08477.13 EON99672.1 - 0.048 13.9 0.1 4.7 7.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EON99672.1 - 0.055 13.5 0.0 5.6 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EON99672.1 - 0.06 12.5 0.1 2.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.17 EON99672.1 - 0.06 13.4 5.8 0.39 10.8 0.0 3.4 4 0 0 4 4 3 0 Helicase HerA, central domain NTPase_1 PF03266.15 EON99672.1 - 0.077 12.9 0.0 14 5.6 0.1 2.9 3 0 0 3 3 3 0 NTPase AAA_16 PF13191.6 EON99672.1 - 0.08 13.3 0.0 2.3 8.6 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 EON99672.1 - 0.084 12.0 0.0 5.9 6.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_27 PF13514.6 EON99672.1 - 0.11 12.1 1.4 7.2 6.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain HEAT PF02985.22 EON99672.1 - 0.12 12.7 0.5 97 3.6 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat Septin PF00735.18 EON99672.1 - 0.13 11.6 0.0 11 5.2 0.0 2.4 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 EON99672.1 - 0.18 11.3 0.1 12 5.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3584 PF12128.8 EON99672.1 - 0.25 8.8 1.2 3.4 5.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HEAT_EZ PF13513.6 EON99672.1 - 0.48 11.0 2.3 20 5.8 0.0 4.0 4 0 0 4 4 3 0 HEAT-like repeat PHD PF00628.29 EON99673.1 - 1e-10 41.4 1.6 2.2e-10 40.3 1.6 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EON99673.1 - 0.0027 17.2 2.4 0.0045 16.5 2.4 1.4 1 0 0 1 1 1 1 PHD-finger UIM PF02809.20 EON99673.1 - 0.0032 17.3 3.1 0.0079 16.0 3.1 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif zf-CW PF07496.15 EON99673.1 - 0.04 13.9 1.4 0.1 12.6 1.4 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger CEBP_ZZ PF16366.5 EON99673.1 - 0.093 13.0 1.8 0.18 12.0 1.8 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain C1_2 PF03107.16 EON99673.1 - 0.44 10.9 3.0 6.5 7.2 0.2 2.6 2 0 0 2 2 2 0 C1 domain C1_1 PF00130.22 EON99673.1 - 0.97 9.4 5.1 1.6 8.7 0.6 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3043 PF11241.8 EON99673.1 - 1.3 9.1 8.4 1.9 8.5 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Nup54 PF13874.6 EON99674.1 - 1.2e-39 135.7 0.6 1.2e-39 135.7 0.6 2.2 3 0 0 3 3 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 EON99674.1 - 1.4e-15 56.5 9.8 2.8e-15 55.6 9.8 1.5 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Adhesin_P1_N PF18652.1 EON99674.1 - 0.0049 16.9 1.3 0.012 15.6 1.3 1.7 1 0 0 1 1 1 1 Adhesin P1 N-terminal domain Nucleoporin_FG PF13634.6 EON99674.1 - 0.012 16.4 13.0 0.022 15.6 13.0 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeat region V-SNARE_C PF12352.8 EON99674.1 - 0.018 15.3 0.1 1.4 9.3 0.0 2.5 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Nbl1_Borealin_N PF10444.9 EON99674.1 - 0.072 12.7 0.5 0.68 9.6 0.1 2.4 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal DUF3552 PF12072.8 EON99674.1 - 0.2 11.0 8.4 2.3 7.6 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DivIVA PF05103.13 EON99674.1 - 0.42 10.7 4.8 0.24 11.5 1.4 2.2 1 1 1 2 2 2 0 DivIVA protein CREPT PF16566.5 EON99674.1 - 0.54 10.4 3.9 0.41 10.8 1.3 2.0 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Cnn_1N PF07989.11 EON99674.1 - 1.7 8.8 7.5 9.3 6.5 0.1 3.0 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 PMSI1 PF15322.6 EON99674.1 - 1.9 7.9 5.4 0.68 9.3 2.1 1.8 2 0 0 2 2 2 0 Protein missing in infertile sperm 1, putative BAR_2 PF10455.9 EON99674.1 - 2 7.5 7.6 0.11 11.6 1.6 1.7 2 1 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF4337 PF14235.6 EON99674.1 - 6 7.0 6.5 0.57 10.3 1.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) CHCH PF06747.13 EON99675.1 - 1.7e-08 34.3 12.0 3.2e-07 30.3 1.9 2.6 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 EON99675.1 - 0.0011 19.0 4.2 0.081 12.9 1.2 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 EON99675.1 - 0.0098 16.2 4.3 1.5 9.2 1.6 2.4 2 0 0 2 2 2 2 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 EON99675.1 - 0.015 15.3 7.6 0.044 13.8 0.8 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like ANAPC5 PF12862.7 EON99676.1 - 2.6e-33 113.9 5.9 6e-32 109.6 3.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 EON99676.1 - 0.00045 20.7 1.3 2.5 8.7 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 EON99676.1 - 0.011 15.5 0.2 0.13 11.9 0.1 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 EON99676.1 - 0.014 15.7 0.4 4 7.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EON99676.1 - 0.058 14.2 6.6 3.5 8.7 0.4 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EON99676.1 - 0.08 13.6 5.6 2.4 9.0 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4607 PF15380.6 EON99676.1 - 0.2 11.1 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) TPR_7 PF13176.6 EON99676.1 - 0.73 10.0 2.7 7.6 6.8 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EON99676.1 - 0.99 9.4 4.3 12 5.9 0.2 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat WSC PF01822.19 EON99677.1 - 4e-15 55.8 8.4 5.3e-15 55.4 8.4 1.2 1 0 0 1 1 1 1 WSC domain SUN PF03856.13 EON99678.1 - 6.7e-76 255.0 7.5 8.2e-76 254.7 7.5 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Peptidase_M3 PF01432.20 EON99679.1 - 4.3e-120 402.1 0.0 6e-120 401.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 EON99679.1 - 0.086 12.5 0.2 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Sortilin-Vps10 PF15902.5 EON99680.1 - 1.4e-294 976.6 18.4 5.1e-151 503.5 6.9 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EON99680.1 - 1.7e-90 301.9 23.2 5.7e-48 163.5 5.8 2.9 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EON99680.1 - 8.9e-08 31.0 44.0 2.8 8.3 1.4 11.8 11 0 0 11 11 11 5 BNR/Asp-box repeat CHB_HEX_C PF03174.13 EON99680.1 - 0.00045 20.1 2.3 0.057 13.4 0.1 4.2 3 0 0 3 3 3 1 Chitobiase/beta-hexosaminidase C-terminal domain DUF2561 PF10812.8 EON99680.1 - 0.0038 17.3 0.2 0.0069 16.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) Rotamase_2 PF13145.6 EON99680.1 - 0.0098 16.7 0.4 0.022 15.6 0.4 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain PSII_BNR PF14870.6 EON99680.1 - 0.01 15.1 0.7 0.22 10.7 0.0 3.3 3 1 0 3 3 3 0 Photosynthesis system II assembly factor YCF48 BNR_2 PF13088.6 EON99680.1 - 0.17 11.2 10.5 2.3 7.4 0.4 5.8 4 3 1 5 5 5 0 BNR repeat-like domain preSET_CXC PF18264.1 EON99680.1 - 0.58 10.7 9.1 3.9 8.0 1.2 2.8 2 0 0 2 2 2 0 CXC domain IMS PF00817.20 EON99681.1 - 3.4e-39 134.2 0.0 7.3e-39 133.1 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 EON99681.1 - 8.8e-28 96.6 3.0 2.2e-27 95.3 3.0 1.7 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 EON99681.1 - 1.1e-15 56.5 18.4 9.8e-08 31.2 2.6 4.0 4 0 0 4 4 4 3 Ubiquitin binding region IMS_C PF11799.8 EON99681.1 - 7.5e-12 46.0 0.0 1.6e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 EON99681.1 - 1.8e-05 25.0 0.0 7.2e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain DUF1805 PF08827.11 EON99681.1 - 0.0008 19.7 0.0 0.035 14.4 0.0 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1805) mCpol PF18182.1 EON99681.1 - 0.0015 18.8 0.0 0.004 17.5 0.0 1.6 1 0 0 1 1 1 1 minimal CRISPR polymerase domain BRCT PF00533.26 EON99681.1 - 0.0036 17.7 0.0 0.011 16.1 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain MgtE_N PF03448.17 EON99681.1 - 0.013 16.0 1.6 4.6 7.9 0.0 3.8 3 1 1 4 4 4 0 MgtE intracellular N domain LIG3_BRCT PF16759.5 EON99681.1 - 0.028 14.7 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 EON99681.1 - 0.074 13.4 1.9 0.24 11.8 0.1 2.8 3 0 0 3 3 3 0 IMS family HHH motif NOG1_N PF17835.1 EON99681.1 - 0.094 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 NOG1 N-terminal helical domain ApoO PF09769.9 EON99682.1 - 1.1e-43 148.3 0.2 6.8e-43 145.8 0.0 2.0 2 0 0 2 2 2 1 Apolipoprotein O OpcA PF07239.11 EON99682.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein OpcA DAGAT PF03982.13 EON99683.1 - 1.6e-100 335.8 0.0 2.2e-100 335.4 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase CDP-OH_P_transf PF01066.21 EON99683.1 - 0.19 12.5 1.2 0.35 11.7 1.2 1.4 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase Diphthami_syn_2 PF01902.17 EON99684.1 - 1.7e-20 73.4 0.0 7.3e-16 58.3 0.0 3.1 2 1 0 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EON99684.1 - 8.8e-10 38.6 0.0 1.1e-05 25.4 0.0 4.0 3 1 0 3 3 3 2 Endoribonuclease L-PSP HTH_IclR PF09339.10 EON99684.1 - 0.13 12.0 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain COesterase PF00135.28 EON99685.1 - 4.6e-72 243.5 0.0 5.6e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EON99685.1 - 0.001 19.0 0.9 0.0038 17.1 0.9 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EON99685.1 - 0.0017 17.9 0.2 0.0026 17.3 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family 7tm_2 PF00002.24 EON99686.1 - 1.1e-05 24.9 7.0 1.1e-05 24.9 7.0 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 EON99686.1 - 0.03 13.4 2.2 0.059 12.5 2.2 1.5 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor DC_STAMP PF07782.13 EON99686.1 - 0.51 10.1 2.7 2 8.2 0.6 2.5 2 1 0 2 2 2 0 DC-STAMP-like protein Mito_carr PF00153.27 EON99687.1 - 2.1e-61 203.8 2.2 3.1e-21 75.1 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Spore_YhaL PF14147.6 EON99687.1 - 0.17 11.6 0.8 5.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Sporulation protein YhaL Serine_protease PF18405.1 EON99687.1 - 0.25 10.4 0.8 4.4 6.4 0.1 2.7 3 0 0 3 3 3 0 Gammaproteobacterial serine protease RED_N PF07808.13 EON99688.1 - 1.7e-07 31.1 8.1 1.7e-07 31.1 8.1 3.4 3 1 0 3 3 3 1 RED-like protein N-terminal region zf-C2H2 PF00096.26 EON99689.1 - 2.6e-12 46.5 12.0 5.9e-06 26.5 0.8 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EON99689.1 - 2.3e-08 34.2 10.3 0.0008 20.0 0.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EON99689.1 - 6.7e-08 32.6 12.0 5.1e-07 29.8 3.8 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EON99689.1 - 4.8e-07 29.9 4.2 0.0015 18.7 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EON99689.1 - 9.2e-07 29.1 4.9 0.00011 22.4 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EON99689.1 - 0.00055 19.9 10.1 0.0062 16.5 1.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 EON99689.1 - 0.022 14.4 3.5 1.6 8.4 0.1 2.6 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf_UBZ PF18439.1 EON99689.1 - 0.037 13.6 2.8 1.2 8.8 0.2 2.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 EON99689.1 - 0.079 12.7 7.0 0.71 9.7 0.1 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 EON99689.1 - 0.17 11.9 5.7 0.1 12.7 1.6 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 EON99689.1 - 1.1 9.7 4.4 16 5.9 0.5 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) IU_nuc_hydro PF01156.19 EON99690.1 - 4.9e-78 262.8 0.2 1e-75 255.1 0.0 2.0 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase Cellulase PF00150.18 EON99691.1 - 2.2e-39 135.6 0.1 2.6e-39 135.3 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peripla_BP_4 PF13407.6 EON99691.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain Methyltransf_23 PF13489.6 EON99692.1 - 2e-15 57.0 0.0 1.5e-13 50.9 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON99692.1 - 4.7e-11 43.3 0.0 1.3e-09 38.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON99692.1 - 2.2e-10 41.2 0.0 8.9e-08 32.8 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON99692.1 - 1e-08 35.7 0.0 1.3e-07 32.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON99692.1 - 5.7e-07 29.4 0.0 9.9e-05 22.2 0.0 2.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 EON99692.1 - 0.00067 19.2 0.0 0.0028 17.2 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EON99692.1 - 0.0059 16.2 0.0 0.043 13.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EON99692.1 - 0.0088 15.4 0.0 0.084 12.2 0.0 2.3 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EON99692.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EON99692.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 EON99692.1 - 0.17 11.2 0.0 1.5 8.1 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase domain Rotamase PF00639.21 EON99693.1 - 4.3e-23 82.1 0.0 5.8e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EON99693.1 - 1.1e-16 61.4 0.0 1.5e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EON99693.1 - 1e-06 28.7 2.2 1.9e-06 27.8 2.2 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 EON99693.1 - 8.2e-05 23.4 0.0 0.00012 23.0 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain MAM PF00629.23 EON99693.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 1 0 1 1 1 0 MAM domain, meprin/A5/mu WW_1 PF18507.1 EON99693.1 - 0.13 11.9 1.9 0.25 11.1 1.9 1.5 1 0 0 1 1 1 0 WW domain RINGv PF12906.7 EON99694.1 - 2.5e-17 62.7 8.3 4.2e-17 62.0 8.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EON99694.1 - 0.0077 16.5 9.0 0.013 15.8 9.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 EON99694.1 - 0.22 11.6 1.9 0.59 10.2 1.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EON99694.1 - 0.47 10.4 5.6 0.83 9.6 5.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EON99694.1 - 3.4 7.5 7.1 5.6 6.8 7.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ferric_reduct PF01794.19 EON99695.1 - 3.1e-17 62.9 13.0 3.1e-17 62.9 13.0 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Methyltransf_23 PF13489.6 EON99696.1 - 3.5e-18 66.0 0.0 4e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON99696.1 - 6.2e-10 39.1 0.0 0.00036 20.3 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EON99696.1 - 3e-09 37.5 0.0 2.3e-08 34.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EON99696.1 - 1e-05 25.1 0.0 0.00034 20.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EON99696.1 - 2.1e-05 25.2 0.0 0.00044 20.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON99696.1 - 5e-05 23.9 0.0 0.00018 22.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EON99696.1 - 0.0021 18.2 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EON99696.1 - 0.0046 16.4 0.0 0.029 13.9 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 EON99696.1 - 0.0097 15.3 0.0 0.019 14.4 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 EON99696.1 - 0.011 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 EON99696.1 - 0.029 13.7 0.0 0.062 12.6 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase domain TauD PF02668.16 EON99697.1 - 1.1e-10 41.8 0.0 1.5e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EON99697.1 - 0.00091 18.4 0.0 0.0023 17.1 0.0 1.6 2 0 0 2 2 2 1 CsiD Apolipoprotein PF01442.18 EON99698.1 - 0.078 12.9 41.9 3.5 7.4 11.2 7.3 5 4 0 5 5 5 0 Apolipoprotein A1/A4/E domain AF0941-like PF14591.6 EON99698.1 - 0.42 11.2 2.0 0.81 10.3 0.3 2.2 2 0 0 2 2 2 0 AF0941-like Exo70 PF03081.15 EON99698.1 - 1.8 7.5 8.1 0.15 11.1 1.0 2.8 4 0 0 4 4 4 0 Exo70 exocyst complex subunit CBFD_NFYB_HMF PF00808.23 EON99698.1 - 8.6 6.7 6.7 6.1 7.2 2.2 3.3 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TRI12 PF06609.13 EON99699.1 - 9.5e-06 24.3 0.8 1.1e-05 24.1 0.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3087 PF11286.8 EON99699.1 - 0.0085 15.6 4.4 0.014 14.9 2.3 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3087) Sugar_tr PF00083.24 EON99699.1 - 0.025 13.5 5.8 0.029 13.2 5.8 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter tRNA-synt_1d PF00750.19 EON99700.1 - 2.4e-102 342.5 2.0 3.1e-102 342.1 2.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EON99700.1 - 7.4e-30 103.6 0.6 1.5e-29 102.6 0.6 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EON99700.1 - 0.0077 16.8 0.0 0.019 15.5 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain MFS_1 PF07690.16 EON99702.1 - 1.8e-31 109.4 24.1 1.8e-31 109.4 24.1 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON99702.1 - 2.7e-30 105.6 26.1 3.9e-29 101.8 26.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter NPP1 PF05630.11 EON99703.1 - 5.9e-30 104.9 0.2 7.1e-30 104.6 0.2 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Sugar_tr PF00083.24 EON99704.1 - 3.9e-37 128.2 14.9 4.4e-37 128.0 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Gal_mutarotas_2 PF13802.6 EON99704.1 - 0.076 13.3 0.5 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 Galactose mutarotase-like DUF4118 PF13493.6 EON99704.1 - 1.2 9.0 12.9 1.4 8.7 1.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4118) DUF983 PF06170.12 EON99704.1 - 5.4 7.5 7.9 0.16 12.4 1.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF983) Ank_2 PF12796.7 EON99705.1 - 3.6e-27 94.8 0.0 4.2e-13 49.7 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EON99705.1 - 1.1e-24 86.5 1.3 3.8e-07 30.5 0.1 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EON99705.1 - 3.3e-23 81.5 0.0 3.9e-08 33.4 0.0 4.5 2 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EON99705.1 - 2.9e-22 76.3 0.6 1.6e-07 31.1 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EON99705.1 - 9.7e-22 76.4 0.1 3.2e-05 24.2 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat DUF962 PF06127.11 EON99705.1 - 0.28 11.3 2.2 0.7 10.0 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF962) Aldo_ket_red PF00248.21 EON99706.1 - 1.3e-48 165.7 0.0 1.1e-37 129.9 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family LysM PF01476.20 EON99706.1 - 0.066 13.3 0.0 0.71 10.0 0.0 2.2 2 0 0 2 2 2 0 LysM domain P3A PF08727.11 EON99706.1 - 0.086 12.2 0.7 0.25 10.7 0.4 1.8 2 0 0 2 2 2 0 Poliovirus 3A protein like RNA_POL_M_15KD PF02150.16 EON99707.1 - 2.6e-12 46.4 3.1 2.6e-12 46.4 3.1 2.1 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit GFA PF04828.14 EON99707.1 - 0.0017 18.7 4.6 0.55 10.6 0.1 2.2 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme OrfB_Zn_ribbon PF07282.11 EON99707.1 - 0.021 14.7 0.9 2.4 8.2 0.9 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Nudix_N_2 PF14803.6 EON99707.1 - 0.097 12.6 1.0 0.097 12.6 1.0 1.9 2 0 0 2 2 2 0 Nudix N-terminal DZR PF12773.7 EON99707.1 - 0.39 10.8 6.4 0.38 10.8 2.6 2.2 2 0 0 2 2 2 0 Double zinc ribbon BTB PF00651.31 EON99708.1 - 3.8e-06 27.1 0.0 2.1e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain NeA_P2 PF12312.8 EON99708.1 - 0.077 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein GST_C PF00043.25 EON99709.1 - 8.1e-07 29.2 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EON99709.1 - 2.2e-06 27.8 0.0 2.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EON99709.1 - 0.00059 19.8 0.0 0.00084 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_M24 PF00557.24 EON99710.1 - 2.2e-08 34.0 0.0 3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_L14 PF00238.19 EON99711.1 - 2.1e-43 147.3 3.0 2.3e-43 147.2 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PALP PF00291.25 EON99712.1 - 6.5e-65 219.4 0.2 8.3e-65 219.1 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EON99712.1 - 1.3e-12 48.0 0.0 1.7e-08 34.8 0.0 2.8 2 0 0 2 2 2 2 CBS domain adh_short PF00106.25 EON99713.1 - 2.2e-22 79.5 0.0 1.6e-17 63.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON99713.1 - 1.9e-12 47.3 0.0 7.3e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON99713.1 - 1.4e-06 28.4 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON99713.1 - 0.00016 21.2 0.0 0.00071 19.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EON99713.1 - 0.065 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_tran_WecB PF03808.13 EON99713.1 - 0.11 12.5 0.0 3.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Sugar_tr PF00083.24 EON99714.1 - 3.3e-108 362.4 23.0 3.8e-108 362.3 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON99714.1 - 3.6e-33 114.9 34.8 3.9e-22 78.7 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5413 PF17434.2 EON99714.1 - 0.048 14.0 1.7 0.059 13.7 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5413) OATP PF03137.20 EON99714.1 - 0.11 10.8 11.2 0.21 9.8 3.7 3.2 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family YqfD PF06898.11 EON99714.1 - 0.14 11.0 0.1 0.22 10.3 0.1 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD SRPRB PF09439.10 EON99715.1 - 4.1e-29 101.3 0.0 1.4e-28 99.5 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EON99715.1 - 8.4e-06 25.9 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EON99715.1 - 9.3e-05 22.9 0.3 0.00023 21.6 0.3 1.8 1 1 1 2 2 2 1 AAA ATPase domain cobW PF02492.19 EON99715.1 - 0.0015 18.2 0.3 1.7 8.2 0.3 2.2 1 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 EON99715.1 - 0.002 17.6 0.0 0.024 14.1 0.0 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 EON99715.1 - 0.0033 16.9 0.0 0.014 14.8 0.0 1.8 1 1 1 2 2 2 1 Bacterial TniB protein RsgA_GTPase PF03193.16 EON99715.1 - 0.0065 16.4 0.3 0.072 13.0 0.2 2.5 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EON99715.1 - 0.021 15.3 0.0 0.041 14.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Septin PF00735.18 EON99715.1 - 0.029 13.6 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 EON99715.1 - 0.03 14.6 0.1 0.056 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EON99715.1 - 0.033 13.5 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin GTP_EFTU PF00009.27 EON99715.1 - 0.034 13.7 0.0 0.13 11.8 0.0 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_30 PF13604.6 EON99715.1 - 0.042 13.6 0.3 0.065 13.0 0.3 1.2 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EON99715.1 - 0.045 13.5 0.1 2.7 7.7 0.0 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 EON99715.1 - 0.047 13.5 0.3 0.26 11.1 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 EON99715.1 - 0.066 12.6 0.0 0.13 11.6 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_5 PF07728.14 EON99715.1 - 0.068 13.2 0.0 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EON99715.1 - 0.081 13.1 0.4 0.27 11.4 0.4 1.8 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 EON99715.1 - 0.098 12.9 0.0 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EON99715.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EON99715.1 - 0.16 11.9 0.1 0.38 10.8 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 EON99715.1 - 0.19 11.3 0.1 16 5.0 0.0 2.2 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain DUF2828 PF11443.8 EON99716.1 - 2.2e-243 809.0 0.0 2.7e-242 805.4 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF2828) YopD PF05844.12 EON99716.1 - 0.16 11.0 0.9 0.28 10.1 0.9 1.3 1 0 0 1 1 1 0 YopD protein E1-E2_ATPase PF00122.20 EON99717.1 - 1.9e-30 105.8 1.6 3e-24 85.5 0.3 3.1 2 1 0 2 2 2 2 E1-E2 ATPase FAM176 PF14851.6 EON99718.1 - 2.3 7.9 4.7 5.7 6.6 4.7 1.6 1 0 0 1 1 1 0 FAM176 family FAD_binding_4 PF01565.23 EON99719.1 - 1.6e-26 92.7 3.7 2.3e-26 92.2 3.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EON99719.1 - 2.8e-07 30.5 0.0 6.9e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 Berberine and berberine like SIKE PF05769.11 EON99720.1 - 0.00061 19.8 2.9 0.0046 16.9 2.2 2.8 2 1 0 2 2 2 1 SIKE family HAUS-augmin3 PF14932.6 EON99720.1 - 0.0051 16.4 4.2 0.0051 16.4 4.2 3.7 2 2 1 4 4 4 1 HAUS augmin-like complex subunit 3 Prefoldin_2 PF01920.20 EON99720.1 - 0.012 15.6 2.3 3.1 7.8 0.1 4.2 4 0 0 4 4 4 0 Prefoldin subunit DUF1529 PF07485.11 EON99720.1 - 0.045 13.7 0.5 2.4 8.1 0.1 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1259) DUF4795 PF16043.5 EON99720.1 - 0.066 12.8 9.0 0.039 13.6 3.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF5641 PF18701.1 EON99720.1 - 0.084 13.1 0.4 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5641) DUF501 PF04417.12 EON99720.1 - 0.11 12.4 0.3 0.41 10.4 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DASH_Duo1 PF08651.10 EON99720.1 - 0.15 11.8 1.4 3.9 7.3 0.0 3.6 4 0 0 4 4 4 0 DASH complex subunit Duo1 DUF4381 PF14316.6 EON99720.1 - 1.7 8.9 4.8 14 5.9 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DivIC PF04977.15 EON99720.1 - 2.2 8.1 7.9 8.9 6.2 0.3 3.4 3 0 0 3 3 3 0 Septum formation initiator dCMP_cyt_deam_1 PF00383.23 EON99721.1 - 4.6e-07 29.6 0.0 7.6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Peptidase_S8 PF00082.22 EON99722.1 - 3.3e-41 141.5 3.2 5.8e-41 140.7 3.2 1.4 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EON99722.1 - 2.5e-15 57.2 0.0 5.2e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 EON99722.1 - 1.4e-06 28.2 0.2 6.3e-06 26.1 0.2 2.2 1 0 0 1 1 1 1 PA domain FlgD_ig PF13860.6 EON99722.1 - 0.0018 18.1 0.0 0.0062 16.4 0.0 1.9 1 0 0 1 1 1 1 FlgD Ig-like domain RPT PF13446.6 EON99722.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein WD40 PF00400.32 EON99724.1 - 7.1e-43 143.8 20.8 5.8e-09 36.4 0.1 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 EON99724.1 - 2.2e-12 46.6 1.7 4.2e-12 45.7 1.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EON99724.1 - 2.3e-09 36.9 0.4 2.3e-09 36.9 0.4 2.1 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 EON99724.1 - 1.9e-08 34.5 0.1 9.7e-05 22.6 0.0 5.0 3 2 4 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EON99724.1 - 5.4e-06 25.3 2.1 0.8 8.3 0.0 4.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 F-box_4 PF15966.5 EON99724.1 - 0.00021 21.1 0.0 0.00052 19.9 0.0 1.7 1 0 0 1 1 1 1 F-box WD40_like PF17005.5 EON99724.1 - 0.014 14.8 0.0 0.11 11.8 0.1 2.0 2 0 0 2 2 2 0 WD40-like domain PRANC PF09372.10 EON99724.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Ge1_WD40 PF16529.5 EON99724.1 - 0.39 9.6 3.6 6.3 5.7 1.0 3.2 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cofilin_ADF PF00241.20 EON99725.1 - 1.8e-30 105.3 0.0 5.1e-16 58.6 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.27 EON99726.1 - 2.8e-67 222.7 2.2 2.6e-21 75.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein FAD_oxidored PF12831.7 EON99727.1 - 4e-68 230.7 0.0 5.4e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GRAM PF02893.20 EON99727.1 - 0.0076 16.1 0.0 0.91 9.4 0.0 3.0 3 0 0 3 3 3 1 GRAM domain Arginase PF00491.21 EON99728.1 - 2.8e-22 79.5 0.0 3.2e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family SET PF00856.28 EON99729.1 - 4.1e-08 33.8 0.0 2.9e-07 31.0 0.0 2.1 2 1 1 3 3 3 1 SET domain RALF PF05498.11 EON99730.1 - 0.18 12.8 1.6 0.32 12.0 1.6 1.4 1 0 0 1 1 1 0 Rapid ALkalinization Factor (RALF) HeLo PF14479.6 EON99731.1 - 1.8e-08 34.4 1.4 0.0027 17.6 0.0 2.8 2 1 1 3 3 3 2 Prion-inhibition and propagation COesterase PF00135.28 EON99732.1 - 6.2e-91 305.8 0.0 1.2e-90 304.8 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EON99732.1 - 8e-06 25.9 0.1 2.2e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DPBB_1 PF03330.18 EON99733.1 - 3.1e-06 27.4 0.1 2.6e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 EON99733.1 - 0.00028 20.8 0.6 0.00043 20.2 0.6 1.2 1 0 0 1 1 1 1 Pollen allergen BNR PF02012.20 EON99733.1 - 0.015 15.2 0.2 0.063 13.3 0.2 2.2 1 0 0 1 1 1 0 BNR/Asp-box repeat Aldo_ket_red PF00248.21 EON99734.1 - 4.2e-32 111.5 0.0 5.2e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family tRNA-synt_2 PF00152.20 EON99735.1 - 2.7e-70 236.9 0.3 3.8e-70 236.5 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EON99735.1 - 7.5e-09 35.4 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EON99735.1 - 9.4e-08 31.8 0.2 0.0014 18.1 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) UCR_Fe-S_N PF10399.9 EON99735.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Pyr_redox_2 PF07992.14 EON99736.1 - 3e-48 164.6 0.2 5.1e-48 163.8 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 EON99736.1 - 3.3e-19 68.9 0.1 9.6e-19 67.4 0.0 1.8 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 EON99736.1 - 2e-17 63.5 5.6 1.5e-16 60.7 1.2 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 EON99736.1 - 2.8e-13 50.0 10.4 2.3e-11 43.8 4.5 3.0 3 0 0 3 3 2 2 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.6 EON99736.1 - 8.1e-13 48.2 0.0 9.5e-10 38.3 0.0 2.9 2 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 EON99736.1 - 1.1e-12 47.7 0.0 1.3e-11 44.3 0.0 2.6 2 1 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 EON99736.1 - 6.5e-09 35.5 0.0 1.4e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 EON99736.1 - 5.2e-07 29.5 0.5 0.0048 16.8 0.0 3.8 3 1 1 4 4 4 2 Rubredoxin NAD+ reductase C-terminal domain Amino_oxidase PF01593.24 EON99736.1 - 1.6e-05 24.4 0.7 0.044 13.1 0.1 2.3 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EON99736.1 - 0.00013 21.3 0.0 0.00033 20.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EON99736.1 - 0.00026 21.0 1.4 2.3 8.2 0.1 3.8 3 1 1 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 EON99736.1 - 0.01 15.0 0.0 0.025 13.7 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 EON99736.1 - 0.026 14.8 0.6 8.2 6.7 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.21 EON99736.1 - 0.35 10.1 2.0 3.2 7.0 0.2 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ALC PF17527.2 EON99737.1 - 0.21 11.2 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Phage ALC protein Astro_capsid_p PF12226.8 EON99738.1 - 1.6 7.8 8.9 2.1 7.4 8.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Glyco_hydro_3 PF00933.21 EON99739.1 - 9.6e-56 189.5 0.0 1.3e-55 189.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EON99739.1 - 9.9e-52 175.9 0.0 1.9e-51 174.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EON99739.1 - 1.6e-22 79.4 0.7 4.1e-22 78.1 0.0 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF11 PF01345.18 EON99739.1 - 0.018 15.3 0.4 0.049 13.9 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF11 ToxS PF17323.2 EON99739.1 - 0.022 14.4 0.1 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 Trans-membrane regulatory protein ToxS DUF2456 PF10445.9 EON99740.1 - 2e-16 59.9 1.1 2e-16 59.9 1.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) IBV_3C PF03620.13 EON99740.1 - 0.064 13.7 1.3 0.18 12.3 1.3 1.7 1 0 0 1 1 1 0 IBV 3C protein PXA PF02194.15 EON99741.1 - 1.6e-54 184.6 0.4 8.3e-54 182.3 0.3 2.3 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 EON99741.1 - 1.7e-28 99.5 0.0 5e-28 97.9 0.0 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 EON99741.1 - 6.4e-21 74.5 0.4 4.1e-20 71.8 0.4 2.3 2 0 0 2 2 2 1 PX domain RGS PF00615.19 EON99741.1 - 8e-09 35.8 0.0 2.4e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain CPDase PF07823.11 EON99741.1 - 0.071 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein A_deaminase PF00962.22 EON99742.1 - 6.4e-75 252.5 0.0 1.5e-74 251.3 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase Abhydrolase_6 PF12697.7 EON99742.1 - 6.5e-15 56.3 0.1 1.2e-14 55.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON99742.1 - 0.016 14.9 0.0 4.9 6.7 0.0 3.5 4 0 0 4 4 4 0 alpha/beta hydrolase fold Amidohydro_1 PF01979.20 EON99742.1 - 0.025 13.9 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase family DUF900 PF05990.12 EON99742.1 - 0.088 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2063 PF09836.9 EON99742.1 - 0.098 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative DNA-binding domain adh_short_C2 PF13561.6 EON99743.1 - 1.3e-51 175.4 0.1 1.6e-51 175.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON99743.1 - 1e-42 145.8 0.5 1.6e-42 145.2 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON99743.1 - 2.5e-11 43.8 0.1 3.2e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON99743.1 - 0.00015 21.3 0.2 0.0004 19.9 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EON99743.1 - 0.0025 17.3 0.2 0.0042 16.5 0.2 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EON99743.1 - 0.0028 16.7 0.3 0.0042 16.1 0.3 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Lactonase PF10282.9 EON99744.1 - 1.5e-17 63.9 0.0 2e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Glyco_hydro_2_C PF02836.17 EON99745.1 - 8.4e-103 343.6 0.2 1.4e-102 342.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 EON99745.1 - 8.6e-62 208.9 0.0 1.5e-61 208.1 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 EON99745.1 - 1.7e-23 83.4 0.3 6.5e-23 81.5 0.2 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 EON99745.1 - 5.3e-19 68.5 0.0 2e-18 66.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 EON99745.1 - 4.4e-13 49.9 0.1 1.2e-12 48.5 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 EON99745.1 - 0.059 13.9 0.0 0.18 12.4 0.0 1.8 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Abhydrolase_3 PF07859.13 EON99746.1 - 0.016 15.0 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ceramidase_alk PF04734.13 EON99747.1 - 6.6e-224 744.2 0.0 7.6e-224 744.0 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EON99747.1 - 2.4e-60 203.2 0.1 4.1e-60 202.5 0.1 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal RTT107_BRCT_5 PF16770.5 EON99748.1 - 6.8e-35 119.0 0.0 3.5e-31 107.0 0.0 4.0 4 0 0 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 EON99748.1 - 6.6e-34 115.7 0.6 8.4e-20 70.5 0.2 4.8 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.26 EON99748.1 - 1.1e-21 77.0 0.1 1.7e-07 31.5 0.0 5.4 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EON99748.1 - 2.2e-21 76.1 0.0 6.3e-05 23.3 0.0 5.8 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EON99748.1 - 8.8e-09 35.5 0.1 0.45 10.8 0.0 3.6 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EON99748.1 - 9.3e-07 28.9 0.2 0.058 13.5 0.0 4.1 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain ADH_N PF08240.12 EON99749.1 - 2.2e-25 88.6 3.9 4.6e-25 87.6 3.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON99749.1 - 1.3e-15 57.5 0.0 3.6e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Lactamase_B_2 PF12706.7 EON99750.1 - 1.1e-27 96.8 0.0 1.5e-26 93.2 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EON99750.1 - 5.1e-09 36.2 0.0 8.9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF3756 PF12581.8 EON99750.1 - 0.023 14.6 0.4 0.68 9.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3756) Glucosamine_iso PF01182.20 EON99751.1 - 4e-20 72.7 0.0 6.7e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase MR_MLE_C PF13378.6 EON99752.1 - 7.9e-57 192.3 0.0 1.2e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EON99752.1 - 0.004 17.3 0.2 0.01 16.1 0.0 1.7 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 EON99752.1 - 0.049 12.8 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus ESCRT-II PF05871.12 EON99753.1 - 3.9e-58 195.7 0.0 5.5e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit FGGY_C PF02782.16 EON99756.1 - 3.4e-74 248.9 1.1 6.3e-74 248.0 1.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EON99756.1 - 5.7e-63 212.7 0.0 8e-63 212.3 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EON99756.1 - 0.5 10.6 2.2 5.4 7.3 0.1 2.8 2 1 2 4 4 4 0 Acyl-CoA dehydrogenase, C-terminal domain Amidohydro_1 PF01979.20 EON99757.1 - 1.7e-15 57.2 0.0 4e-15 56.0 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EON99757.1 - 1.6e-11 44.3 0.0 1.8e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Nramp PF01566.18 EON99758.1 - 3.9e-91 305.7 14.9 3.9e-91 305.7 14.9 2.1 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Glyco_hydro_3 PF00933.21 EON99759.1 - 1.8e-63 214.8 0.0 2.5e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EON99759.1 - 0.00036 20.6 0.0 0.00067 19.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.25 EON99759.1 - 0.066 13.5 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Hexokinase_2 PF03727.16 EON99760.1 - 3.4e-52 177.3 0.0 4.7e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EON99760.1 - 3.1e-43 148.0 0.0 6.2e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 Hexokinase Glyco_hydro_61 PF03443.14 EON99761.1 - 5.2e-69 232.3 0.2 9.5e-69 231.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 His_Phos_1 PF00300.22 EON99762.1 - 3.4e-20 72.6 0.0 1.2e-19 70.7 0.0 1.9 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) adh_short PF00106.25 EON99763.1 - 6.1e-24 84.6 1.0 4.5e-21 75.2 0.3 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON99763.1 - 4.9e-14 52.4 1.5 1.3e-10 41.3 0.7 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON99763.1 - 7.8e-11 42.2 0.2 1.2e-10 41.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Chromo_shadow PF01393.19 EON99764.1 - 2.9e-19 68.9 2.1 5.7e-17 61.5 0.1 2.5 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 EON99764.1 - 1.5e-13 50.4 0.5 1.5e-13 50.4 0.5 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DNA_pol_phi PF04931.13 EON99764.1 - 0.037 12.1 16.1 0.049 11.7 16.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi ELM2 PF01448.24 EON99764.1 - 0.089 13.6 0.8 0.31 11.8 0.8 1.9 1 1 0 1 1 1 0 ELM2 domain CCDC53 PF10152.9 EON99764.1 - 2.6 8.4 5.5 1.7 9.0 0.3 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Gryzun PF07919.12 EON99765.1 - 1.4e-154 516.2 0.1 1.6e-154 516.0 0.1 1.0 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 EON99765.1 - 0.025 14.6 0.0 0.066 13.2 0.0 1.8 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking BCS1_N PF08740.11 EON99766.1 - 6.6e-58 195.8 4.3 6.6e-58 195.8 4.3 2.5 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 EON99766.1 - 1.1e-17 64.7 0.0 2.3e-09 37.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EON99766.1 - 0.00034 20.4 0.0 0.00062 19.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EON99766.1 - 0.0012 18.8 0.0 0.0046 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EON99766.1 - 0.0017 18.7 0.0 0.0017 18.7 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 EON99766.1 - 0.0041 16.7 0.0 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EON99766.1 - 0.012 15.4 16.3 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EON99766.1 - 0.077 13.3 0.0 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EON99766.1 - 0.084 13.0 0.0 0.32 11.1 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase GAGA_bind PF06217.12 EON99766.1 - 2.9 8.1 21.0 6 7.1 21.0 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family SET PF00856.28 EON99766.1 - 4.3 7.7 7.6 4.2 7.7 5.7 2.0 2 0 0 2 2 2 0 SET domain XRN_M PF17846.1 EON99766.1 - 6.2 5.7 16.6 9.3 5.1 16.6 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Raftlin PF15250.6 EON99766.1 - 6.7 5.3 16.9 12 4.5 16.9 1.4 1 0 0 1 1 1 0 Raftlin PAP1 PF08601.10 EON99767.1 - 1.5e-84 284.9 56.6 1.1e-59 203.0 6.8 3.4 3 1 1 4 4 4 3 Transcription factor PAP1 bZIP_1 PF00170.21 EON99767.1 - 5e-09 36.1 8.4 1.1e-08 35.1 8.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EON99767.1 - 0.0084 16.6 7.0 0.018 15.6 7.0 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor SHE3 PF17078.5 EON99767.1 - 0.014 15.1 4.0 0.02 14.6 2.3 1.9 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 SlyX PF04102.12 EON99767.1 - 0.022 15.4 0.6 0.022 15.4 0.6 2.3 2 1 1 3 3 2 0 SlyX bZIP_2 PF07716.15 EON99767.1 - 0.023 14.8 9.8 0.062 13.4 9.4 2.0 1 1 0 1 1 1 0 Basic region leucine zipper dsrm PF00035.26 EON99767.1 - 0.031 15.0 0.3 0.078 13.7 0.3 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif CCDC158 PF15921.5 EON99767.1 - 0.033 12.0 4.7 0.0098 13.8 1.8 1.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 158 MbeD_MobD PF04899.12 EON99767.1 - 0.11 12.6 0.4 0.24 11.5 0.4 1.5 1 0 0 1 1 1 0 MbeD/MobD like CDC45 PF02724.14 EON99767.1 - 0.17 10.2 11.9 0.24 9.7 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 EON99767.1 - 0.36 10.2 16.9 0.55 9.6 16.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Epimerase PF01370.21 EON99768.1 - 4.9e-25 88.4 0.0 6.6e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EON99768.1 - 6.9e-20 71.7 0.0 5.7e-18 65.4 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EON99768.1 - 1.3e-12 47.3 0.0 1.9e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EON99768.1 - 1.3e-08 34.3 0.0 2e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EON99768.1 - 3.4e-08 33.0 0.0 1.7e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 EON99768.1 - 5.4e-08 32.5 0.0 8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EON99768.1 - 3.1e-07 29.8 0.0 1.2e-05 24.6 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EON99768.1 - 1.8e-06 28.0 0.0 2.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EON99768.1 - 7.7e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EON99768.1 - 8.4e-05 22.2 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase WD40 PF00400.32 EON99769.1 - 3.6e-22 78.2 16.4 0.00011 22.9 0.1 7.0 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON99769.1 - 6.3e-13 48.8 4.2 2.8e-06 27.6 0.0 4.1 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 EON99769.1 - 3.8e-06 27.0 5.2 0.0029 17.6 0.1 2.8 2 2 0 2 2 2 2 Transcription factor IIIC subunit delta N-term IKI3 PF04762.12 EON99769.1 - 0.0053 14.8 1.8 0.18 9.8 0.0 2.1 2 0 0 2 2 2 2 IKI3 family Spermine_synth PF01564.17 EON99770.1 - 4.2e-06 26.3 0.0 8.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 EON99770.1 - 0.0023 17.8 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON99770.1 - 0.029 15.1 0.0 0.064 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EON99770.1 - 0.084 13.5 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PEMT PF04191.13 EON99771.1 - 2e-32 111.7 1.9 3.1e-32 111.1 1.9 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase RXT2_N PF08595.11 EON99772.1 - 9.9e-47 158.9 0.0 9.9e-47 158.9 0.0 3.4 3 1 1 4 4 4 1 RXT2-like, N-terminal UvrD-helicase PF00580.21 EON99774.1 - 4.2e-64 217.0 1.3 6.9e-62 209.8 0.1 2.7 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EON99774.1 - 2.8e-35 122.3 1.1 1.5e-34 119.9 0.7 2.0 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EON99774.1 - 1.5e-29 103.3 0.0 2.6e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON99774.1 - 3.7e-09 36.6 0.3 9.3e-05 22.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EON99774.1 - 0.0012 18.7 0.1 0.066 12.9 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase SurA_N_3 PF13624.6 EON99775.1 - 0.0031 17.3 4.9 0.0058 16.4 4.9 1.4 1 0 0 1 1 1 1 SurA N-terminal domain Rotamase PF00639.21 EON99775.1 - 0.97 10.4 0.0 0.97 10.4 0.0 3.4 2 1 1 3 3 3 0 PPIC-type PPIASE domain Goodbye PF17109.5 EON99775.1 - 1.1 9.7 13.7 1.6 9.2 0.1 4.0 2 2 1 3 3 3 0 fungal STAND N-terminal Goodbye domain DUF3450 PF11932.8 EON99775.1 - 3.3 6.9 20.8 20 4.4 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Phage_GPO PF05929.11 EON99775.1 - 5.5 6.5 13.6 0.62 9.6 8.8 1.9 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2937 PF11157.8 EON99775.1 - 6.5 6.4 8.3 59 3.3 7.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF4078 PF13300.6 EON99776.1 - 3.2e-29 101.1 22.3 3.2e-29 101.1 22.3 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF4078) PHR PF08005.12 EON99776.1 - 0.16 12.6 0.0 0.35 11.5 0.0 1.5 2 0 0 2 2 2 0 PHR domain Atg14 PF10186.9 EON99776.1 - 2.3 7.2 12.6 0.48 9.5 8.2 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 NTP_transferase PF00483.23 EON99777.1 - 5.1e-52 176.9 0.0 9.4e-52 176.0 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 EON99777.1 - 1.5e-17 62.6 13.0 1.4e-10 40.4 2.0 3.7 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EON99777.1 - 4.5e-10 40.1 0.0 6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EON99777.1 - 3.6e-06 26.6 1.2 3.6e-06 26.6 1.2 3.4 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EON99777.1 - 9.3e-05 20.8 0.1 0.00018 19.8 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 EON99777.1 - 0.029 14.3 0.0 0.075 12.9 0.0 1.6 2 0 0 2 2 2 0 Cytidylyltransferase IspD PF01128.19 EON99777.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase LCM PF04072.14 EON99778.1 - 1.1e-18 67.9 0.0 1.4e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF2065 PF09838.9 EON99778.1 - 0.0089 16.0 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2065) BSD PF03909.17 EON99779.1 - 1.4e-20 73.1 0.2 2.7e-20 72.1 0.2 1.5 1 0 0 1 1 1 1 BSD domain Suf PF05843.14 EON99779.1 - 0.12 12.3 6.2 0.02 14.9 1.9 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Rad10 PF03834.14 EON99780.1 - 1.2e-46 157.4 0.0 1.7e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EON99780.1 - 0.0013 19.3 0.3 0.0028 18.2 0.0 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain Ion_trans_2 PF07885.16 EON99781.1 - 5.9e-31 106.3 32.9 1.6e-18 66.4 7.6 3.1 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 EON99781.1 - 0.0012 18.1 0.3 0.0012 18.1 0.3 2.6 2 1 0 2 2 2 1 Ion transport protein UCR_hinge PF02320.16 EON99782.1 - 3.1e-28 97.7 10.7 5.8e-28 96.9 10.7 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Mpp10 PF04006.12 EON99782.1 - 0.027 12.9 16.4 0.03 12.8 16.4 1.0 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 EON99782.1 - 0.44 9.8 18.1 0.47 9.7 18.1 1.0 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EON99782.1 - 0.56 8.4 21.5 0.57 8.3 21.5 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EON99782.1 - 0.64 9.4 21.9 0.7 9.3 21.9 1.0 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EON99782.1 - 0.75 8.0 13.8 0.75 8.0 13.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Myc_N PF01056.18 EON99782.1 - 0.83 9.5 13.5 1 9.2 13.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF913 PF06025.12 EON99782.1 - 1.4 7.8 6.4 1.6 7.6 6.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 EON99782.1 - 1.7 8.4 13.1 2 8.2 13.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRN3 PF05327.11 EON99782.1 - 1.8 7.0 12.3 1.9 6.9 12.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 eIF-3c_N PF05470.12 EON99782.1 - 1.9 6.7 9.3 2.2 6.5 9.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DNA_pol_phi PF04931.13 EON99782.1 - 2.3 6.2 27.5 2.4 6.2 27.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi SAPS PF04499.15 EON99782.1 - 2.5 6.8 8.4 2.8 6.6 8.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BIRC6 PF12356.8 EON99782.1 - 3.2 7.1 6.0 3.8 6.9 6.0 1.4 1 1 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 CobT PF06213.12 EON99782.1 - 4 6.8 20.7 4.6 6.5 20.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Tim54 PF11711.8 EON99782.1 - 4.6 5.9 11.3 5.2 5.7 11.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PTPRCAP PF15713.5 EON99782.1 - 4.7 7.5 27.8 2.4 8.4 15.3 2.0 1 1 1 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 EON99782.1 - 5.2 5.7 8.5 5.6 5.6 8.5 1.0 1 0 0 1 1 1 0 Presenilin PPP4R2 PF09184.11 EON99782.1 - 7.1 6.1 20.9 9.2 5.8 20.9 1.1 1 0 0 1 1 1 0 PPP4R2 T3SS_needle_E PF08988.10 EON99783.1 - 0.1 12.8 0.4 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Ndc80_HEC PF03801.13 EON99784.1 - 2.6e-59 199.2 0.5 2.6e-59 199.2 0.5 2.0 2 0 0 2 2 2 1 HEC/Ndc80p family Spc7 PF08317.11 EON99784.1 - 0.0013 17.7 8.9 0.0013 17.7 8.9 3.0 4 0 0 4 4 4 2 Spc7 kinetochore protein DUF2935 PF11155.8 EON99784.1 - 0.02 15.3 6.0 2.1 8.7 0.1 3.4 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) TPR_MLP1_2 PF07926.12 EON99784.1 - 3.1 7.9 44.6 0.05 13.7 11.6 4.0 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 EON99784.1 - 3.2 8.3 11.1 9.2 6.8 0.9 3.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 EON99784.1 - 6.2 7.2 18.1 9 6.6 0.4 4.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) AMP-binding PF00501.28 EON99785.1 - 8.9e-86 288.1 0.0 1.3e-85 287.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme MARVEL PF01284.23 EON99786.1 - 8.5e-05 22.6 5.8 0.00011 22.3 5.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain SirB PF04247.12 EON99786.1 - 0.02 15.0 6.4 0.062 13.4 4.7 2.2 1 1 1 2 2 2 0 Invasion gene expression up-regulator, SirB COX2_TM PF02790.15 EON99786.1 - 0.29 11.3 4.5 0.95 9.6 4.2 2.0 1 1 1 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Fig1 PF12351.8 EON99786.1 - 1.9 8.4 8.4 3.5 7.5 8.4 1.5 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Putative_PNPOx PF01243.20 EON99787.1 - 1.7e-05 24.9 0.0 0.005 17.0 0.0 2.5 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.21 EON99787.1 - 0.0046 17.6 0.0 0.0098 16.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_4 PF01565.23 EON99788.1 - 7.5e-16 58.1 0.0 1.2e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Aldo_ket_red PF00248.21 EON99789.1 - 6.2e-73 245.6 0.0 7e-73 245.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_Tnp_1 PF01527.20 EON99789.1 - 0.18 12.2 0.0 33 4.9 0.0 3.1 3 0 0 3 3 3 0 Transposase MFS_1 PF07690.16 EON99790.1 - 1.2e-32 113.2 56.4 7.8e-29 100.7 41.2 3.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EON99790.1 - 1.8e-14 53.1 15.2 2.7e-14 52.5 4.3 2.7 2 1 1 3 3 3 2 Fungal trichothecene efflux pump (TRI12) SGL PF08450.12 EON99792.1 - 0.0017 18.0 0.1 0.18 11.4 0.0 2.4 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region GSDH PF07995.11 EON99792.1 - 0.004 16.5 0.8 0.018 14.3 0.5 2.3 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase Utp14 PF04615.13 EON99796.1 - 2.1e-203 678.0 54.8 2.1e-203 678.0 54.8 2.7 1 1 1 3 3 3 1 Utp14 protein FAD_binding_3 PF01494.19 EON99797.1 - 6e-16 58.6 6.1 1.9e-14 53.7 6.1 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EON99797.1 - 9.9e-05 22.5 1.2 0.00037 20.7 1.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 EON99797.1 - 0.00066 18.8 0.0 0.0014 17.7 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 EON99797.1 - 0.0033 16.7 1.2 0.0033 16.7 1.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON99797.1 - 0.0086 15.2 2.7 0.013 14.7 2.7 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EON99797.1 - 0.019 15.5 0.8 0.23 12.0 1.6 2.2 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EON99797.1 - 0.1 12.2 5.3 0.23 11.0 4.1 1.9 1 1 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 EON99797.1 - 0.55 9.3 1.7 0.75 8.8 1.7 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A polyprenyl_synt PF00348.17 EON99798.1 - 1.8e-17 63.3 0.0 3.7e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Polyprenyl synthetase RRM_1 PF00076.22 EON99799.1 - 3.9e-22 77.8 0.0 1.3e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_4 PF14570.6 EON99800.1 - 9.9e-21 73.3 12.1 2.2e-20 72.2 12.1 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 EON99800.1 - 1.8e-11 43.7 0.1 6.9e-11 41.8 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 EON99800.1 - 1.9e-08 34.0 7.3 1.9e-08 34.0 7.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 EON99800.1 - 6.5e-06 25.7 3.0 8.2e-06 25.4 3.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 EON99800.1 - 5.8e-05 23.3 10.1 5.8e-05 23.3 10.1 2.1 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EON99800.1 - 0.00013 21.8 9.0 0.032 14.1 9.5 2.4 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 SET_assoc PF11767.8 EON99800.1 - 0.00026 20.6 0.0 0.00067 19.2 0.0 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated zf-C3HC4 PF00097.25 EON99800.1 - 0.0043 16.9 9.8 0.0043 16.9 9.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Nup35_RRM_2 PF14605.6 EON99800.1 - 0.0056 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Baculo_IE-1 PF05290.11 EON99800.1 - 0.0062 16.5 5.0 0.015 15.3 5.0 1.6 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 EON99800.1 - 0.0075 16.4 4.2 0.025 14.7 4.2 1.9 1 0 0 1 1 1 1 Zinc-binding RING-finger FYVE_2 PF02318.16 EON99800.1 - 0.012 15.8 4.3 0.012 15.8 4.3 2.4 1 1 1 2 2 2 0 FYVE-type zinc finger zf-RING_5 PF14634.6 EON99800.1 - 0.037 14.0 10.0 0.11 12.5 10.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Rad50_zn_hook PF04423.14 EON99800.1 - 0.053 13.4 1.0 3.6 7.5 0.2 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 EON99800.1 - 0.22 11.6 3.2 0.54 10.3 0.8 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EON99800.1 - 0.62 10.1 9.1 0.47 10.5 5.9 2.4 2 1 1 3 3 2 0 RING-type zinc-finger CTU2 PF10288.9 EON99800.1 - 1.5 9.1 8.5 0.075 13.3 0.8 2.5 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 FYVE PF01363.21 EON99800.1 - 1.9 8.7 12.0 0.13 12.4 6.8 1.9 2 1 0 2 2 1 0 FYVE zinc finger FYDLN_acid PF09538.10 EON99800.1 - 6 7.6 7.6 2.9 8.6 4.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Pyr_redox_2 PF07992.14 EON99801.1 - 1.3e-53 182.1 1.5 1.7e-53 181.8 1.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON99801.1 - 1.7e-17 63.7 2.5 4.9e-15 55.9 0.1 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.20 EON99801.1 - 1.1e-14 54.8 0.1 3.6e-14 53.2 0.0 1.8 2 0 0 2 2 1 1 Rhodanese-like domain Pyr_redox_dim PF02852.22 EON99801.1 - 3.5e-14 53.0 0.8 1.5e-13 51.0 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 EON99801.1 - 6.9e-11 41.9 0.0 2.6e-08 33.5 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON99801.1 - 3e-10 40.2 1.4 0.001 19.2 0.1 3.1 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EON99801.1 - 1e-06 28.6 6.6 1.2 8.7 0.0 4.5 5 0 0 5 5 5 3 FAD dependent oxidoreductase HI0933_like PF03486.14 EON99801.1 - 0.00042 19.1 0.0 0.34 9.6 0.0 3.2 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.24 EON99801.1 - 0.00063 18.9 2.5 0.19 10.8 0.1 3.1 3 0 0 3 3 3 2 FAD binding domain NAD_binding_7 PF13241.6 EON99801.1 - 0.0012 19.3 0.2 0.8 10.2 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding K_oxygenase PF13434.6 EON99801.1 - 0.004 16.3 0.0 0.0089 15.2 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 EON99801.1 - 0.0081 15.5 1.4 0.25 10.6 0.1 2.6 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EON99801.1 - 0.012 14.7 0.5 11 4.9 0.0 3.1 2 1 1 3 3 3 0 Lycopene cyclase protein Amino_oxidase PF01593.24 EON99801.1 - 0.018 14.4 1.7 12 5.1 0.0 3.6 4 0 0 4 4 4 0 Flavin containing amine oxidoreductase GIDA PF01134.22 EON99801.1 - 0.085 11.9 0.3 0.47 9.5 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A Abhydrolase_3 PF07859.13 EON99803.1 - 1.6e-40 139.2 0.1 5.8e-30 104.7 0.1 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EON99803.1 - 1.5e-12 47.0 0.0 1.8e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 EON99803.1 - 0.0022 17.0 0.2 0.11 11.3 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Hydrolase_4 PF12146.8 EON99803.1 - 0.053 12.8 0.0 0.14 11.4 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Glyco_hydro81C PF17652.1 EON99804.1 - 6.8e-165 548.5 9.9 8.8e-165 548.1 9.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EON99804.1 - 1.3e-113 379.5 3.5 2.1e-113 378.8 3.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Glyco_hydro_31 PF01055.26 EON99805.1 - 9.1e-111 371.1 0.7 1.1e-110 370.9 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EON99805.1 - 2.2e-14 53.5 0.0 5.2e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like ubiquitin PF00240.23 EON99806.1 - 4e-132 430.2 20.4 2.1e-32 110.7 0.6 4.5 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 EON99806.1 - 5.6e-61 202.3 21.0 1.2e-14 53.8 0.7 4.5 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like BRAP2 PF07576.12 EON99806.1 - 2.2e-31 108.0 0.0 3.8e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 Ubiquitin_2 PF14560.6 EON99806.1 - 2.5e-19 69.5 10.6 0.0025 18.2 0.1 5.1 4 0 0 4 4 4 4 Ubiquitin-like domain zf-UBP PF02148.19 EON99806.1 - 2e-17 63.3 7.6 4.9e-17 62.0 7.6 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein TBK1_ULD PF18396.1 EON99806.1 - 6.9e-14 51.5 2.6 0.15 12.0 0.0 4.4 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EON99806.1 - 1e-12 48.1 2.9 0.025 14.7 0.0 4.8 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EON99806.1 - 1.1e-12 48.2 7.0 0.15 12.4 0.1 4.5 4 0 0 4 4 4 4 Ubiquitin-like domain DUF2407 PF10302.9 EON99806.1 - 4.2e-09 36.9 9.1 0.23 12.0 0.2 4.9 2 1 2 5 5 4 4 DUF2407 ubiquitin-like domain zf-RING_2 PF13639.6 EON99806.1 - 7.4e-08 32.6 9.3 7.4e-08 32.6 9.3 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EON99806.1 - 1.7e-06 27.7 10.0 3.6e-06 26.7 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EON99806.1 - 0.00011 21.8 4.9 0.00033 20.3 4.9 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EON99806.1 - 0.00023 21.1 3.0 0.00023 21.1 3.0 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EON99806.1 - 0.00028 20.7 8.4 0.00064 19.5 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EON99806.1 - 0.00061 19.7 7.1 0.00061 19.7 7.1 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EON99806.1 - 0.00067 19.9 6.9 0.0017 18.6 6.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain DUF3861 PF12977.7 EON99806.1 - 0.0012 18.9 2.0 71 3.7 0.0 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 EON99806.1 - 0.0032 17.3 4.7 46 4.0 0.0 4.5 4 0 0 4 4 4 0 ACT domain zf-C3HC4_3 PF13920.6 EON99806.1 - 0.0034 17.2 6.5 0.0034 17.2 6.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EON99806.1 - 0.0098 15.7 2.7 0.025 14.5 2.7 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Big_7 PF17957.1 EON99806.1 - 0.012 16.4 0.3 2.5e+02 2.5 0.0 4.4 4 0 0 4 4 4 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 EON99806.1 - 0.019 15.1 3.6 38 4.4 0.0 3.8 4 0 0 4 4 3 0 UDP-glucose:Glycoprotein Glucosyltransferase Ubiquitin_4 PF18036.1 EON99806.1 - 0.036 14.1 24.0 78 3.4 0.2 8.2 8 0 0 8 8 8 0 Ubiquitin-like domain zf-ANAPC11 PF12861.7 EON99806.1 - 0.043 13.9 6.4 0.11 12.6 6.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger T3SSipB PF16535.5 EON99806.1 - 0.19 12.2 5.6 0.59 10.6 5.6 1.8 1 0 0 1 1 1 0 Type III cell invasion protein SipB TSC22 PF01166.18 EON99806.1 - 0.24 11.7 3.4 1 9.7 3.4 2.2 1 0 0 1 1 1 0 TSC-22/dip/bun family YcgR_2 PF12945.7 EON99806.1 - 0.27 11.4 6.2 1.3e+02 2.8 0.1 4.3 4 0 0 4 4 4 0 Flagellar protein YcgR FlgN PF05130.12 EON99806.1 - 0.88 10.1 12.0 1.4 9.5 11.4 1.6 1 1 0 1 1 1 0 FlgN protein YabA PF06156.13 EON99806.1 - 5.1 7.8 10.8 8.4 7.1 4.8 2.6 1 1 1 2 2 2 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 EON99806.1 - 8.3 5.9 9.2 15 5.0 9.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit BHD_3 PF10405.9 EON99807.1 - 2.7e-26 91.8 0.1 4.3e-26 91.1 0.1 1.3 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EON99807.1 - 1.7e-22 79.0 0.0 3.7e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EON99807.1 - 4.7e-21 75.5 0.2 1.6e-20 73.8 0.2 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 PDH PF02153.17 EON99807.1 - 0.03 13.4 0.0 0.052 12.5 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Pex14_N PF04695.13 EON99808.1 - 7.8e-34 117.6 7.7 7.8e-34 117.6 7.7 3.9 2 2 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1978 PF09321.10 EON99808.1 - 0.00055 19.3 4.4 0.00081 18.8 4.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1978) FlgN PF05130.12 EON99808.1 - 0.0028 18.2 7.4 0.0056 17.2 7.4 1.4 1 0 0 1 1 1 1 FlgN protein DUF3584 PF12128.8 EON99808.1 - 0.0042 14.7 5.9 0.0056 14.3 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Prominin PF05478.11 EON99808.1 - 0.0064 14.5 0.5 0.009 14.0 0.5 1.2 1 0 0 1 1 1 1 Prominin Golgin_A5 PF09787.9 EON99808.1 - 0.011 15.3 7.5 0.017 14.6 7.5 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Cytochrom_B562 PF07361.11 EON99808.1 - 0.039 14.6 2.1 0.083 13.5 1.6 1.8 1 1 0 1 1 1 0 Cytochrome b562 Baculo_p24 PF05073.12 EON99808.1 - 0.12 12.1 1.0 0.27 11.0 0.2 1.8 1 1 1 2 2 2 0 Baculovirus P24 capsid protein HLH PF00010.26 EON99808.1 - 0.12 12.3 4.3 34 4.5 4.3 3.0 1 1 0 1 1 1 0 Helix-loop-helix DNA-binding domain FIVAR PF07554.13 EON99808.1 - 0.12 13.1 9.7 0.47 11.2 1.0 3.6 3 0 0 3 3 3 0 FIVAR domain DUF572 PF04502.13 EON99808.1 - 0.21 11.2 5.8 0.3 10.7 5.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) LMBR1 PF04791.16 EON99808.1 - 0.22 10.4 0.1 0.29 10.0 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Wtap PF17098.5 EON99808.1 - 0.25 11.3 8.4 0.44 10.5 2.1 2.5 1 1 1 2 2 2 0 WTAP/Mum2p family Baculo_PEP_C PF04513.12 EON99808.1 - 0.27 11.2 5.9 0.98 9.5 1.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 EON99808.1 - 0.28 11.3 3.4 0.42 10.7 3.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 EON99808.1 - 1.6 9.0 8.5 4.1 7.7 2.8 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SYCE1 PF15233.6 EON99808.1 - 1.9 8.6 15.4 0.14 12.3 9.5 1.8 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 DUF1043 PF06295.12 EON99808.1 - 2.1 8.4 6.4 11 6.0 6.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) SlyX PF04102.12 EON99808.1 - 2.7 8.7 6.4 1.4 9.6 1.7 2.7 2 1 0 2 2 2 0 SlyX Spc7 PF08317.11 EON99808.1 - 3.1 6.6 9.1 5.5 5.8 9.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Spectrin PF00435.21 EON99808.1 - 8.4 6.9 11.9 9.8 6.7 3.6 2.8 2 1 1 3 3 3 0 Spectrin repeat ANAPC4_WD40 PF12894.7 EON99809.1 - 6.8e-06 26.3 0.0 0.00019 21.6 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EON99809.1 - 2.3e-05 25.1 0.0 0.2 12.6 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EON99809.1 - 0.00076 18.6 0.0 0.00092 18.4 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region PQQ PF01011.21 EON99809.1 - 0.016 15.1 0.1 0.051 13.5 0.0 1.9 2 0 0 2 2 2 0 PQQ enzyme repeat eIF2A PF08662.11 EON99809.1 - 0.036 13.9 0.0 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Inv-AAD PF18785.1 EON99810.1 - 9.2e-62 206.6 0.0 1.1e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EON99810.1 - 5.1e-15 55.2 0.0 7.8e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 EON99810.1 - 0.0001 22.2 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain MafB19-deam PF14437.6 EON99810.1 - 0.00075 19.3 0.0 0.0013 18.5 0.0 1.4 1 1 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EON99810.1 - 0.043 13.9 0.0 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Pkinase PF00069.25 EON99811.1 - 5e-09 35.9 0.0 7.1e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EON99811.1 - 1.5e-05 25.1 0.2 0.00017 21.6 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EON99811.1 - 0.015 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EON99811.1 - 0.049 12.9 0.0 0.068 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase WaaY PF06176.11 EON99811.1 - 0.05 13.2 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 EON99811.1 - 0.18 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EON99811.1 - 0.21 10.9 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Methyltransf_4 PF02390.17 EON99812.1 - 3.7e-57 192.6 0.1 4.6e-57 192.2 0.1 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EON99812.1 - 5.2e-05 23.9 0.0 0.00017 22.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EON99812.1 - 0.00039 20.0 0.0 0.0015 18.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EON99812.1 - 0.00087 20.0 0.0 0.0023 18.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON99812.1 - 0.0018 18.1 0.1 0.0046 16.8 0.1 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON99812.1 - 0.011 16.4 0.0 0.046 14.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EON99812.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EON99812.1 - 0.095 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EON99812.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain FmrO PF07091.11 EON99812.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) MRP-L27 PF09809.9 EON99814.1 - 8.8e-16 57.7 0.4 1.4e-15 57.1 0.3 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 Pkinase PF00069.25 EON99815.1 - 5.5e-59 199.7 0.0 8e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON99815.1 - 3.2e-30 105.3 0.0 4.3e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EON99815.1 - 0.0032 16.8 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EON99815.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EON99815.1 - 0.025 14.5 0.3 0.025 14.5 0.3 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EON99815.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Suc_Fer-like PF06999.12 EON99816.1 - 9e-72 241.0 0.0 1.1e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like FAD_binding_4 PF01565.23 EON99817.1 - 1.4e-19 70.2 0.1 2.1e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EON99817.1 - 5e-07 29.7 0.1 1.7e-06 28.0 0.2 1.8 2 0 0 2 2 2 1 Berberine and berberine like ALO PF04030.14 EON99817.1 - 0.0084 15.9 0.0 0.11 12.3 0.1 2.2 2 1 0 2 2 2 1 D-arabinono-1,4-lactone oxidase UCH PF00443.29 EON99818.1 - 1e-27 97.3 0.0 1.8e-27 96.5 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EON99818.1 - 5.2e-18 65.7 0.0 8.9e-18 64.9 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Homoserine_dh PF00742.19 EON99819.1 - 4.7e-51 173.1 0.0 6e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EON99819.1 - 6.4e-17 62.3 0.0 1e-16 61.6 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain RecQ5 PF06959.11 EON99819.1 - 0.16 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) Zip PF02535.22 EON99820.1 - 6.2e-35 121.0 0.0 7.3e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter AAA PF00004.29 EON99821.1 - 1.8e-21 77.0 0.0 5.9e-21 75.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EON99821.1 - 0.0001 22.7 1.3 0.00052 20.4 0.3 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EON99821.1 - 0.00015 21.8 0.0 0.00033 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EON99821.1 - 0.00047 20.3 0.0 0.0016 18.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EON99821.1 - 0.0013 19.1 0.3 0.013 15.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 EON99821.1 - 0.0053 16.5 0.4 0.029 14.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EON99821.1 - 0.013 15.2 0.1 0.031 14.0 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EON99821.1 - 0.014 15.5 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EON99821.1 - 0.024 14.4 0.0 0.065 13.0 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EON99821.1 - 0.032 14.0 0.3 0.078 12.7 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EON99821.1 - 0.043 13.8 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 EON99821.1 - 0.075 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA_25 PF13481.6 EON99821.1 - 0.075 12.6 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain CPSF100_C PF13299.6 EON99821.1 - 0.33 11.1 3.6 0.2 11.8 0.6 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal AAA_11 PF13086.6 EON99821.1 - 0.68 9.7 0.0 0.68 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain Vfa1 PF08432.10 EON99821.1 - 1.5 9.1 14.0 0.72 10.2 7.6 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CENP-B_dimeris PF09026.10 EON99821.1 - 2.1 8.8 9.1 0.37 11.2 3.4 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain VHS PF00790.19 EON99822.1 - 2.3e-41 140.9 2.0 1.5e-40 138.3 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 EON99822.1 - 4.6e-15 55.5 4.1 7.8e-15 54.8 4.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 EON99822.1 - 3.4e-06 26.6 17.5 0.0014 18.4 1.5 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 EON99822.1 - 0.021 15.0 1.7 0.053 13.7 1.7 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger BAF1_ABF1 PF04684.13 EON99822.1 - 0.037 13.1 0.1 0.046 12.8 0.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ribosomal_S30AE PF02482.19 EON99822.1 - 0.057 14.2 0.0 0.51 11.2 0.1 2.5 3 0 0 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein Fer4_2 PF12797.7 EON99822.1 - 0.27 11.4 7.4 1.3 9.2 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain SDA1 PF05285.12 EON99823.1 - 0.0026 17.3 2.6 0.0038 16.7 2.6 1.3 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 EON99823.1 - 0.0055 15.1 0.3 0.0058 15.0 0.3 1.2 1 0 0 1 1 1 1 CDC45-like protein FAM176 PF14851.6 EON99823.1 - 0.021 14.5 0.3 0.034 13.8 0.3 1.3 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 EON99823.1 - 0.049 13.0 9.9 0.069 12.5 9.9 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 EON99823.1 - 5.6 7.0 6.4 8.9 6.3 6.4 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2014 PF09427.10 EON99824.1 - 8.7e-116 385.9 7.7 1.3e-115 385.3 7.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 EON99824.1 - 6.5e-17 61.2 0.9 2e-16 59.7 0.9 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PsbL PF02419.17 EON99824.1 - 0.012 15.5 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 PsbL protein SUIM_assoc PF16619.5 EON99824.1 - 0.026 14.6 13.3 0.021 14.9 3.2 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FAM176 PF14851.6 EON99824.1 - 0.37 10.5 1.9 1.3 8.7 1.9 2.0 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 EON99824.1 - 1.1 9.7 7.3 3 8.3 7.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tom22 PF04281.13 EON99824.1 - 6.1 6.6 8.4 6.3 6.6 5.1 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Glyoxalase PF00903.25 EON99825.1 - 3.3e-41 140.5 0.2 2.2e-20 73.2 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EON99825.1 - 1.3e-15 57.6 0.0 7.1e-06 26.3 0.0 3.9 2 2 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EON99825.1 - 1.4e-07 32.2 0.0 0.0024 18.6 0.0 2.8 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EON99825.1 - 1.2e-06 28.4 0.2 0.081 12.9 0.0 4.2 4 0 0 4 4 4 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EON99825.1 - 1.4e-06 28.6 0.0 0.23 11.5 0.0 3.3 3 1 0 3 3 3 2 Glyoxalase-like domain DUF1338 PF07063.13 EON99825.1 - 0.0058 15.9 0.1 7.7 5.6 0.0 3.6 3 2 1 4 4 4 1 Domain of unknown function (DUF1338) CppA_N PF14506.6 EON99825.1 - 0.0084 16.2 0.1 1.3 9.1 0.0 2.4 2 0 0 2 2 2 1 CppA N-terminal MoaF PF10703.9 EON99825.1 - 0.021 14.8 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 MoaF N-terminal domain Pkinase PF00069.25 EON99826.1 - 2.1e-05 24.0 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Drf_GBD PF06371.13 EON99827.1 - 9.5e-14 51.4 2.0 3.7e-12 46.2 2.0 2.4 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain MAPEG PF01124.18 EON99828.1 - 2.1e-22 79.4 0.4 2.5e-22 79.2 0.4 1.0 1 0 0 1 1 1 1 MAPEG family p450 PF00067.22 EON99830.1 - 1.8e-27 96.2 0.0 2.4e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ZT_dimer PF16916.5 EON99831.1 - 3.6e-09 36.6 0.4 6.8e-09 35.7 0.4 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 EON99831.1 - 5.8e-08 32.7 8.9 8.1e-08 32.2 8.9 1.2 1 0 0 1 1 1 1 Cation efflux family Glyco_hydro_43 PF04616.14 EON99832.1 - 8.1e-06 25.3 0.1 1.2e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 2-Hacid_dh_C PF02826.19 EON99834.1 - 1.4e-51 174.4 0.1 2.1e-51 173.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EON99834.1 - 3e-35 120.8 0.4 1.1e-34 118.9 0.2 2.0 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 EON99834.1 - 0.00028 20.6 0.1 0.0076 16.0 0.0 3.1 3 0 0 3 3 3 1 ACT domain XdhC_C PF13478.6 EON99834.1 - 0.038 14.5 0.0 0.092 13.3 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain DnaJ PF00226.31 EON99835.1 - 3.1e-23 81.7 1.1 1e-22 80.0 1.1 2.0 1 0 0 1 1 1 1 DnaJ domain Nif11 PF07862.11 EON99835.1 - 0.0068 16.7 0.5 1.1 9.7 0.0 3.6 3 0 0 3 3 3 1 Nif11 domain IDEAL PF08858.10 EON99835.1 - 0.042 13.6 0.6 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 IDEAL domain RPT PF13446.6 EON99835.1 - 0.052 13.5 0.0 0.21 11.5 0.0 2.0 1 0 0 1 1 1 0 A repeated domain in UCH-protein MFS_1 PF07690.16 EON99836.1 - 1.3e-34 119.7 27.1 3.2e-34 118.4 27.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily WGG PF10273.9 EON99837.1 - 2e-35 121.3 0.1 3.6e-35 120.5 0.1 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 TFIIF_alpha PF05793.12 EON99837.1 - 0.013 14.1 5.9 0.014 14.0 5.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4619 PF15398.6 EON99837.1 - 0.089 12.3 0.2 0.11 12.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) NOA36 PF06524.12 EON99837.1 - 3.3 6.9 7.4 4.2 6.6 7.4 1.1 1 0 0 1 1 1 0 NOA36 protein DUF1604 PF07713.13 EON99838.1 - 8.5e-41 137.7 2.3 8.5e-41 137.7 2.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EON99838.1 - 4.4e-07 29.7 4.1 4.2e-06 26.5 2.3 2.6 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EON99838.1 - 0.001 19.1 1.6 0.017 15.2 0.6 3.1 2 1 0 2 2 2 1 G-patch domain ACP_PD PF04336.12 EON99838.1 - 0.19 12.2 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase GST_C PF00043.25 EON99839.1 - 1.3e-10 41.4 0.2 3.4e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EON99839.1 - 4.3e-09 36.6 0.0 8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EON99839.1 - 9.5e-07 28.8 0.4 2.5e-06 27.4 0.4 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EON99839.1 - 2.3e-05 24.7 0.0 4.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EON99839.1 - 0.00012 22.3 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EON99839.1 - 0.00072 19.7 0.0 0.0029 17.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF21 PF01595.20 EON99840.1 - 1.7e-34 119.0 0.0 2.8e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EON99840.1 - 2.2e-06 28.0 0.6 0.0053 17.2 0.0 3.0 2 0 0 2 2 2 2 CBS domain Glyco_hydro_47 PF01532.20 EON99841.1 - 1.5e-120 403.2 0.0 1.7e-120 403.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Piwi PF02171.17 EON99842.1 - 1e-63 215.4 0.0 1.6e-63 214.8 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoL2 PF16488.5 EON99842.1 - 5.7e-13 49.0 0.0 2.1e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoL1 PF08699.10 EON99842.1 - 7.1e-11 41.6 0.0 1.6e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 EON99842.1 - 1.1e-06 28.5 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 EON99842.1 - 0.0021 18.3 0.2 0.0071 16.6 0.3 1.9 2 0 0 2 2 2 1 Mid domain of argonaute Sugar_tr PF00083.24 EON99843.1 - 2.9e-32 112.2 1.4 3.7e-32 111.8 1.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MtN3_slv PF03083.16 EON99843.1 - 6.1 6.9 9.3 1.4 9.0 0.1 3.4 4 0 0 4 4 4 0 Sugar efflux transporter for intercellular exchange DUF3487 PF11990.8 EON99843.1 - 7.3 6.5 6.7 3.5 7.5 0.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3487) Lipase_GDSL_2 PF13472.6 EON99844.1 - 2.8e-07 31.1 0.3 4e-07 30.6 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EON99844.1 - 4.5e-07 30.0 0.0 6.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Acyltransferase PF01553.21 EON99845.1 - 8e-10 38.5 0.0 0.00014 21.5 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Methyltransf_23 PF13489.6 EON99846.1 - 1.2e-20 74.0 0.0 1.6e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON99846.1 - 2.7e-13 50.5 0.0 1.8e-12 47.8 0.0 2.3 3 1 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON99846.1 - 6.9e-10 38.9 0.0 2.3e-08 33.9 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON99846.1 - 2.1e-09 37.9 0.0 1.1e-08 35.6 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON99846.1 - 1.1e-08 35.7 0.0 3.1e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON99846.1 - 0.00011 21.7 0.0 0.00091 18.6 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EON99846.1 - 0.0015 18.1 0.0 0.0043 16.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 EON99846.1 - 0.0033 16.9 0.0 0.0063 15.9 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 EON99846.1 - 0.0046 16.7 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 EON99846.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 EON99846.1 - 0.02 14.2 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain NDT80_PhoG PF05224.12 EON99847.1 - 1.9e-35 122.8 0.0 2.6e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Pectinesterase PF01095.19 EON99848.1 - 8.9e-52 175.6 7.0 1.2e-51 175.2 7.0 1.1 1 0 0 1 1 1 1 Pectinesterase Rcd1 PF04078.13 EON99850.1 - 3.5e-126 419.8 5.9 4.1e-126 419.6 5.9 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Opi1 PF08618.10 EON99850.1 - 0.14 11.4 3.2 0.2 10.9 3.2 1.2 1 0 0 1 1 1 0 Transcription factor Opi1 COesterase PF00135.28 EON99850.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family CTP_transf_like PF01467.26 EON99851.1 - 9.3e-25 87.5 0.0 1.4e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like VWA_2 PF13519.6 EON99851.1 - 0.13 12.9 0.0 0.27 11.9 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain COX15-CtaA PF02628.15 EON99852.1 - 7.6e-112 373.6 7.8 9.7e-112 373.2 7.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Na_H_Exchanger PF00999.21 EON99853.1 - 8.9e-61 205.8 43.4 1.3e-60 205.2 43.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family KCH PF16944.5 EON99854.1 - 4.3e-96 321.5 5.3 5e-96 321.3 5.3 1.0 1 0 0 1 1 1 1 Fungal potassium channel Pkinase PF00069.25 EON99855.1 - 6.2e-71 238.8 0.0 1.2e-70 237.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON99855.1 - 1.6e-39 135.8 0.0 3.5e-39 134.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EON99855.1 - 7.1e-19 67.3 0.1 1.4e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 EON99855.1 - 7e-07 28.5 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EON99855.1 - 2.1e-05 24.0 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EON99855.1 - 7e-05 22.3 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EON99855.1 - 0.0024 17.9 0.0 0.014 15.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EON99855.1 - 0.081 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family ABC_tran PF00005.27 EON99856.1 - 6.3e-48 162.8 0.3 1.5e-25 90.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EON99856.1 - 5.5e-22 78.3 35.6 1.4e-14 54.0 22.1 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 EON99856.1 - 1.3e-20 74.4 9.0 1e-05 25.5 0.0 4.6 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON99856.1 - 2.8e-09 36.8 1.5 0.023 14.1 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EON99856.1 - 7.6e-09 35.2 2.7 0.00037 20.2 0.5 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EON99856.1 - 9.6e-05 23.0 6.6 0.077 13.5 0.7 2.4 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.6 EON99856.1 - 0.00012 22.7 0.0 0.0075 17.0 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) RsgA_GTPase PF03193.16 EON99856.1 - 0.00053 19.9 2.7 0.43 10.5 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EON99856.1 - 0.00065 20.1 0.6 1.5 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 EON99856.1 - 0.0022 17.7 0.0 1.2 8.8 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_27 PF13514.6 EON99856.1 - 0.0034 17.0 0.6 2.7 7.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EON99856.1 - 0.017 14.8 3.9 2.7 7.7 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EON99856.1 - 0.03 14.6 0.2 5.3 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EON99856.1 - 0.087 13.3 0.1 6.3 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EON99856.1 - 0.095 12.3 1.4 13 5.3 0.3 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 EON99856.1 - 0.15 12.3 1.2 5.7 7.2 0.2 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EON99856.1 - 0.2 11.6 0.1 18 5.2 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain MukB PF04310.12 EON99856.1 - 0.27 11.0 1.8 22 4.7 0.1 2.6 2 0 0 2 2 2 0 MukB N-terminal Zeta_toxin PF06414.12 EON99856.1 - 0.34 10.1 1.5 14 4.9 0.2 2.5 2 0 0 2 2 2 0 Zeta toxin Bac_luciferase PF00296.20 EON99857.1 - 6.6e-50 170.3 1.6 8.7e-50 169.9 1.6 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase FumaraseC_C PF10415.9 EON99857.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Fumarase C C-terminus HMG_CoA_synt_C PF08540.10 EON99858.1 - 1.1e-100 336.9 0.0 1.5e-100 336.4 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EON99858.1 - 6.4e-95 315.9 0.2 8.9e-95 315.5 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Pyr_redox_2 PF07992.14 EON99859.1 - 3.7e-36 124.9 0.0 4.4e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON99859.1 - 5.7e-16 58.9 0.3 3.5e-11 43.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON99859.1 - 6.3e-06 25.7 0.0 0.00095 18.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON99859.1 - 7.6e-06 25.3 0.0 0.0028 16.8 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EON99859.1 - 2.7e-05 24.2 0.4 1.3 9.0 0.0 4.3 5 0 0 5 5 5 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EON99859.1 - 9.9e-05 21.5 0.0 0.35 9.9 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 EON99859.1 - 0.00049 20.3 0.0 0.044 14.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EON99859.1 - 0.0025 17.1 0.0 0.4 9.9 0.0 2.4 2 0 0 2 2 2 1 Thi4 family TrkA_N PF02254.18 EON99859.1 - 0.0044 17.3 0.0 0.82 9.9 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain HI0933_like PF03486.14 EON99859.1 - 0.018 13.8 0.0 7.1 5.2 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 EON99859.1 - 0.052 13.1 0.0 13 5.2 0.0 2.9 4 0 0 4 4 4 0 FAD dependent oxidoreductase ThiF PF00899.21 EON99859.1 - 0.07 12.5 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 ThiF family GIDA PF01134.22 EON99859.1 - 0.087 11.9 0.1 16 4.5 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Herpes_UL49_1 PF03117.14 EON99859.1 - 0.093 12.0 0.0 0.19 11.0 0.0 1.4 2 0 0 2 2 2 0 UL49 family Trp_halogenase PF04820.14 EON99859.1 - 0.12 11.2 0.0 3 6.6 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase Zn_clus PF00172.18 EON99860.1 - 0.0025 17.9 7.7 0.0061 16.7 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.7 EON99861.1 - 1.5e-10 42.0 2.0 2.9e-10 41.1 2.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON99861.1 - 7.8e-09 35.1 0.0 4.3e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EON99861.1 - 8.7e-05 22.3 0.0 0.00022 20.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EON99861.1 - 0.00062 19.3 0.0 0.0017 17.8 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EON99861.1 - 0.0083 15.1 0.0 0.027 13.4 0.0 1.8 3 0 0 3 3 3 1 Chlorophyllase enzyme Ndr PF03096.14 EON99861.1 - 0.21 10.3 0.0 0.62 8.7 0.0 1.7 2 0 0 2 2 2 0 Ndr family MFS_1 PF07690.16 EON99862.1 - 2e-23 82.9 37.9 3.3e-23 82.2 37.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EON99862.1 - 0.064 12.1 13.4 0.028 13.3 1.6 2.7 1 1 2 3 3 3 0 MFS_1 like family Na_Ca_ex PF01699.24 EON99863.1 - 8.3e-42 142.7 40.9 1.5e-21 77.0 17.9 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Complex1_30kDa PF00329.19 EON99864.1 - 9.8e-45 152.1 0.0 1.4e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Sortilin-Vps10 PF15902.5 EON99866.1 - 6.3e-11 41.7 16.6 3.5e-07 29.4 0.2 5.4 4 2 1 6 6 6 5 Sortilin, neurotensin receptor 3, BNR PF02012.20 EON99866.1 - 0.00022 20.8 39.1 0.37 11.0 0.2 9.2 8 1 1 9 9 9 5 BNR/Asp-box repeat BNR_6 PF15899.5 EON99866.1 - 0.17 12.0 8.1 7.3 7.0 0.0 5.6 6 0 0 6 6 6 0 BNR-Asp box repeat AA_permease PF00324.21 EON99867.1 - 4.5e-28 98.1 29.8 5.6e-28 97.8 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON99867.1 - 3.7e-18 65.6 32.2 4.9e-18 65.2 32.2 1.1 1 0 0 1 1 1 1 Amino acid permease KleE PF17394.2 EON99867.1 - 0.79 10.0 13.3 0.21 11.8 6.5 2.8 3 0 0 3 3 3 0 Uncharacterized KleE stable inheritance protein Pyridox_ox_2 PF12900.7 EON99868.1 - 2.1e-29 102.3 0.0 3.1e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4321 PF14209.6 EON99869.1 - 0.11 12.3 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4321) Peptidase_S9 PF00326.21 EON99871.1 - 4.2e-07 29.7 0.0 0.00015 21.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 EON99871.1 - 0.0047 16.5 0.0 0.028 14.0 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 EON99871.1 - 0.021 14.7 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.13 EON99871.1 - 0.053 12.0 0.0 0.14 10.7 0.0 1.6 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF1100 PF06500.11 EON99871.1 - 0.079 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Esterase_phd PF10503.9 EON99871.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 EON99871.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Oxidored_FMN PF00724.20 EON99872.1 - 4.6e-62 210.3 0.0 5.4e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AAA PF00004.29 EON99873.1 - 1.9e-12 47.7 0.0 9.5e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EON99873.1 - 0.00011 22.6 0.0 0.00039 20.9 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EON99873.1 - 0.0004 20.7 0.0 0.0019 18.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EON99873.1 - 0.00053 19.3 0.0 0.0024 17.2 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_2 PF07724.14 EON99873.1 - 0.0024 18.0 0.0 0.032 14.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EON99873.1 - 0.0031 17.7 0.0 0.0079 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EON99873.1 - 0.0078 16.8 0.0 0.025 15.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EON99873.1 - 0.0082 16.0 0.0 0.024 14.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EON99873.1 - 0.012 15.6 0.0 0.038 14.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EON99873.1 - 0.023 13.7 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 EON99873.1 - 0.03 14.3 0.1 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CbiA PF01656.23 EON99873.1 - 0.038 14.1 0.0 0.088 12.9 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 EON99873.1 - 0.042 14.2 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.18 EON99873.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Hydin_ADK PF17213.3 EON99873.1 - 0.051 13.8 0.8 0.22 11.8 0.0 2.4 3 0 0 3 3 2 0 Hydin Adenylate kinase-like domain KTI12 PF08433.10 EON99873.1 - 0.055 12.9 0.0 2.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RuvB_N PF05496.12 EON99873.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EON99873.1 - 0.07 12.7 0.0 0.45 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EON99873.1 - 0.077 12.9 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 EON99873.1 - 0.2 11.0 0.3 1.4 8.2 0.1 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI MARVEL PF01284.23 EON99874.1 - 1.1e-22 80.6 1.2 1.4e-22 80.3 1.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain Peptidase_M48_N PF16491.5 EON99874.1 - 0.034 14.0 0.4 0.45 10.4 0.1 2.2 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices DUF2207 PF09972.9 EON99874.1 - 0.94 8.2 3.8 13 4.4 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CD20 PF04103.15 EON99874.1 - 1.8 8.7 8.7 5.2 7.1 8.7 1.9 1 1 0 1 1 1 0 CD20-like family DUF3632 PF12311.8 EON99875.1 - 3.6e-17 63.4 2.6 5.4e-17 62.8 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) MHB PF16525.5 EON99875.1 - 0.12 12.7 1.4 2.8 8.3 0.2 2.3 2 0 0 2 2 2 0 Haemophore, haem-binding Transp_cyt_pur PF02133.15 EON99876.1 - 2.7e-22 79.2 40.5 5.2e-22 78.2 40.5 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin IlvN PF07991.12 EON99877.1 - 4e-46 156.6 0.0 5.9e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EON99877.1 - 1.1e-39 135.9 0.0 1.8e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 EON99877.1 - 0.0061 17.1 0.0 0.018 15.6 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.26 EON99878.1 - 4.9e-23 81.5 0.2 9.5e-23 80.6 0.2 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON99878.1 - 7.2e-23 82.1 0.0 1.3e-22 81.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON99878.1 - 1.8e-08 34.3 0.0 1.3e-07 31.5 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain zf-U1 PF06220.12 EON99879.1 - 7e-22 76.9 3.4 1e-21 76.4 3.4 1.3 1 0 0 1 1 1 1 U1 zinc finger Fasciclin PF02469.22 EON99880.1 - 4.8e-24 85.0 0.1 9.6e-11 42.0 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Viral_protease PF08715.10 EON99880.1 - 0.1 11.9 0.0 1.6 8.0 0.0 2.0 2 0 0 2 2 2 0 Papain like viral protease Amidohydro_2 PF04909.14 EON99881.1 - 2.4e-31 109.6 0.3 2.7e-31 109.4 0.3 1.0 1 0 0 1 1 1 1 Amidohydrolase HD PF01966.22 EON99882.1 - 2.4e-05 24.5 0.3 7.8e-05 22.9 0.2 2.0 2 0 0 2 2 2 1 HD domain Fungal_TACC PF12709.7 EON99883.1 - 1.1e-08 35.4 0.4 1.1e-08 35.4 0.4 3.9 4 0 0 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins LPP PF04728.13 EON99883.1 - 0.18 12.2 1.3 3.2 8.2 0.3 2.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper ATG16 PF08614.11 EON99883.1 - 1 9.6 36.5 2 8.6 9.9 3.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TSC22 PF01166.18 EON99883.1 - 3.1 8.2 6.0 22 5.4 0.7 3.3 3 0 0 3 3 3 0 TSC-22/dip/bun family FlaC_arch PF05377.11 EON99883.1 - 4.1 7.9 16.7 0.55 10.7 1.2 4.5 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Shugoshin_N PF07558.11 EON99883.1 - 6.4 6.7 10.6 3.4 7.6 0.9 3.2 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region PCI PF01399.27 EON99884.1 - 0.0065 17.0 0.0 0.015 15.8 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 EON99884.1 - 0.089 13.0 0.1 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Phage_TAC_3 PF06896.11 EON99884.1 - 0.12 12.9 0.9 1.2 9.8 0.0 2.6 3 0 0 3 3 3 0 Phage tail assembly chaperone proteins, TAC TRP PF06011.12 EON99885.1 - 1.1e-165 551.5 32.8 1.4e-165 551.2 32.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EON99885.1 - 9e-43 146.0 0.4 1.6e-42 145.2 0.4 1.4 1 0 0 1 1 1 1 ML-like domain TcpE PF12648.7 EON99885.1 - 2.7 8.6 20.6 0.77 10.3 1.7 3.4 3 1 0 3 3 3 0 TcpE family DUF3433 PF11915.8 EON99886.1 - 1.1e-39 134.7 11.2 6.6e-21 74.6 1.3 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Pho86 PF11124.8 EON99886.1 - 0.08 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 GST_C_2 PF13410.6 EON99888.1 - 1.7e-05 24.8 0.1 3e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EON99888.1 - 2.5e-05 24.4 0.0 4.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EON99888.1 - 0.025 15.0 0.0 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF1382 PF07131.11 EON99888.1 - 0.098 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) AMPK1_CBM PF16561.5 EON99889.1 - 0.00049 20.3 0.1 0.00099 19.3 0.1 1.5 1 1 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_20 PF00686.19 EON99889.1 - 0.053 13.4 0.2 0.11 12.4 0.2 1.6 1 0 0 1 1 1 0 Starch binding domain Apt1 PF10351.9 EON99889.1 - 0.067 12.0 6.2 0.075 11.9 6.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zip PF02535.22 EON99889.1 - 0.21 10.8 2.0 0.22 10.7 2.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3498 PF12004.8 EON99889.1 - 6 5.9 16.3 0.14 11.3 9.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3498) AMP-binding PF00501.28 EON99890.1 - 8.9e-75 251.9 0.0 1.1e-74 251.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EON99890.1 - 6.7e-20 70.8 1.4 6.7e-20 70.8 1.4 2.4 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EON99890.1 - 1.8e-15 57.7 0.1 1.7e-14 54.6 0.0 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain VSP PF03302.13 EON99891.1 - 0.072 11.9 0.8 0.11 11.3 0.8 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein MGC-24 PF05283.11 EON99891.1 - 1.3 9.5 0.0 1.3 9.5 0.0 3.6 3 1 1 5 5 5 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ras PF00071.22 EON99892.1 - 1.3e-51 174.4 0.0 2.2e-51 173.7 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EON99892.1 - 4.5e-18 65.6 0.0 4.5e-17 62.4 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EON99892.1 - 0.0003 20.3 0.0 0.0008 18.9 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EON99892.1 - 0.018 14.9 0.0 5.7 6.8 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 EON99892.1 - 0.025 14.1 0.1 0.41 10.1 0.0 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B SRPRB PF09439.10 EON99892.1 - 0.063 12.7 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EON99892.1 - 0.079 13.3 0.0 0.14 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EON99892.1 - 0.092 12.0 0.0 0.19 11.0 0.0 1.5 2 0 0 2 2 2 0 Septin AAA_25 PF13481.6 EON99892.1 - 0.11 12.1 0.2 0.28 10.7 0.1 1.7 1 1 1 2 2 2 0 AAA domain Abhydrolase_4 PF08386.10 EON99892.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.6 2 0 0 2 2 2 0 TAP-like protein DUF2075 PF09848.9 EON99892.1 - 0.14 11.3 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 EON99892.1 - 0.15 12.2 0.0 0.52 10.4 0.0 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain C1q PF00386.21 EON99893.1 - 0.17 12.1 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 C1q domain SNF2_N PF00176.23 EON99894.1 - 6.8e-51 173.0 0.0 1e-50 172.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EON99894.1 - 5.3e-18 65.4 0.0 2.2e-17 63.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EON99894.1 - 5.5e-09 35.6 1.1 1.4e-08 34.2 1.1 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EON99894.1 - 0.0013 18.7 0.0 0.0029 17.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Chromo PF00385.24 EON99894.1 - 0.0055 16.6 5.6 0.03 14.2 1.5 3.5 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1087 PF06465.13 EON99894.1 - 0.011 15.8 0.2 0.028 14.4 0.2 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) zf-PHD-like PF15446.6 EON99894.1 - 0.025 14.2 0.1 0.072 12.7 0.1 1.7 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain SnAC PF14619.6 EON99894.1 - 0.98 10.1 10.1 0.95 10.1 0.4 3.2 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex SUR7 PF06687.12 EON99895.1 - 1.8e-19 70.2 12.7 2.3e-19 69.9 12.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF1218 PF06749.12 EON99895.1 - 2 9.0 8.9 3.6 8.2 5.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) MBF1 PF08523.10 EON99896.1 - 4.4e-27 94.3 2.9 1e-26 93.2 2.9 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EON99896.1 - 3.1e-11 43.2 0.0 5.3e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EON99896.1 - 0.0017 18.7 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MRP-L27 PF09809.9 EON99896.1 - 0.0059 16.4 0.1 0.0072 16.1 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Pyr_redox_dim PF02852.22 EON99896.1 - 0.031 14.5 0.1 0.042 14.1 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain HTH_24 PF13412.6 EON99896.1 - 0.093 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding KilA-N PF04383.13 EON99897.1 - 0.00018 21.3 0.0 0.0041 16.9 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain bZIP_1 PF00170.21 EON99898.1 - 2.5e-13 49.9 6.4 3.9e-13 49.3 6.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EON99898.1 - 7.1e-07 29.2 6.4 1.3e-06 28.3 6.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EON99898.1 - 0.00021 21.7 2.8 0.00041 20.8 2.8 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor FAM76 PF16046.5 EON99898.1 - 0.034 13.5 4.1 0.042 13.2 4.1 1.1 1 0 0 1 1 1 0 FAM76 protein HALZ PF02183.18 EON99898.1 - 0.041 14.1 0.4 0.066 13.4 0.4 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF1319 PF07028.11 EON99898.1 - 0.13 12.5 0.6 0.19 12.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) DivIC PF04977.15 EON99898.1 - 0.14 11.9 0.9 0.24 11.2 0.9 1.3 1 0 0 1 1 1 0 Septum formation initiator Macoilin PF09726.9 EON99898.1 - 0.25 9.9 5.9 0.29 9.6 5.9 1.0 1 0 0 1 1 1 0 Macoilin family NpwBP PF12622.7 EON99898.1 - 0.57 11.0 8.1 1.1 10.1 0.2 2.6 2 0 0 2 2 2 0 mRNA biogenesis factor Chitin_synth_1 PF01644.17 EON99900.1 - 5.3e-69 231.4 0.0 7.6e-69 230.9 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EON99900.1 - 2.3e-27 94.8 0.1 4e-27 94.0 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EON99900.1 - 2.1e-26 92.7 0.1 7.9e-22 77.6 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EON99900.1 - 6e-09 36.1 4.9 5.7e-08 32.9 4.9 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 UQ_con PF00179.26 EON99902.1 - 3e-38 130.6 0.0 3.8e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme OTU PF02338.19 EON99903.1 - 4.6e-24 85.3 0.0 1.5e-23 83.6 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EON99903.1 - 0.012 15.0 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Peptidase C65 Otubain DUF3043 PF11241.8 EON99903.1 - 2 8.4 19.3 1.4 9.0 8.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) F-box-like PF12937.7 EON99904.1 - 2e-05 24.4 1.3 3.7e-05 23.5 1.3 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EON99904.1 - 0.00032 20.5 0.3 0.0008 19.2 0.3 1.6 1 0 0 1 1 1 1 F-box domain GFA PF04828.14 EON99905.1 - 1.8e-23 82.7 0.0 2.4e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 EON99905.1 - 0.3 11.2 4.5 1.8 8.7 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.6 EON99905.1 - 0.37 10.7 0.1 0.37 10.7 0.1 2.9 3 0 0 3 3 3 0 Nudix N-terminal zf-NADH-PPase PF09297.11 EON99905.1 - 0.72 9.6 0.1 0.72 9.6 0.1 2.8 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain CDT1_C PF16679.5 EON99906.1 - 4.7e-27 94.3 0.9 4.7e-27 94.3 0.9 1.7 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain MFS_1 PF07690.16 EON99907.1 - 1e-31 110.1 17.2 1e-31 110.1 17.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily PTR2 PF00854.21 EON99907.1 - 0.0084 15.0 4.1 0.069 12.0 0.2 2.5 2 1 0 3 3 3 2 POT family Ost5 PF05251.12 EON99907.1 - 0.37 11.1 11.1 0.083 13.2 0.9 3.0 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 FA_desaturase PF00487.24 EON99907.1 - 3.5 7.4 8.2 1.5 8.6 2.9 2.5 2 1 0 2 2 2 0 Fatty acid desaturase Amidohydro_2 PF04909.14 EON99908.1 - 1.9e-06 27.9 0.0 3.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Sdh5 PF03937.16 EON99909.1 - 3.2e-24 84.7 0.1 1e-23 83.0 0.1 1.8 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase DLH PF01738.18 EON99910.1 - 6.1e-22 78.2 0.0 5.5e-21 75.1 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EON99910.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EON99910.1 - 0.079 12.6 0.0 3 7.4 0.0 2.5 1 1 0 2 2 2 0 alpha/beta hydrolase fold adh_short PF00106.25 EON99911.1 - 1.2e-41 142.3 0.0 1.8e-41 141.8 0.0 1.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON99911.1 - 1.8e-29 103.0 0.2 5.7e-29 101.3 0.1 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON99911.1 - 3e-08 33.8 0.3 4.5e-08 33.2 0.3 1.2 1 0 0 1 1 1 1 KR domain Flu_C_NS1 PF03506.13 EON99911.1 - 0.012 15.6 0.0 0.17 11.9 0.0 2.1 1 1 1 2 2 2 0 Influenza C non-structural protein (NS1) Aldedh PF00171.22 EON99912.1 - 1.8e-13 49.8 6.7 2.5e-07 29.6 6.0 2.8 1 1 1 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.17 EON99912.1 - 0.027 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) Rep_fac-A_C PF08646.10 EON99913.1 - 2.4e-55 186.3 3.9 8.6e-54 181.3 1.9 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EON99913.1 - 1.8e-39 133.6 0.3 1.5e-38 130.7 0.2 2.2 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 EON99913.1 - 8.3e-21 73.9 0.0 1.7e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EON99913.1 - 6.6e-17 61.3 0.3 6.1e-10 39.0 0.0 4.3 4 1 0 4 4 4 3 OB-fold nucleic acid binding domain Fumerase_C PF05683.12 EON99913.1 - 0.037 13.3 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 Fumarase C-terminus zf-like PF04071.12 EON99913.1 - 0.061 13.2 0.3 0.16 11.9 0.3 1.7 1 0 0 1 1 1 0 Cysteine-rich small domain DUF4539 PF15072.6 EON99913.1 - 0.13 12.3 0.0 1.4 9.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4539) HAD_2 PF13419.6 EON99914.1 - 1e-11 45.3 0.0 3.8e-11 43.4 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EON99914.1 - 8.7e-10 39.2 0.0 1.2e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EON99914.1 - 4.1e-06 26.8 0.0 7.7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like EMP24_GP25L PF01105.24 EON99915.1 - 2.2e-40 138.5 0.0 2.5e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ADH_N PF08240.12 EON99916.1 - 2.3e-23 82.2 4.3 3.5e-23 81.6 4.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON99916.1 - 4.6e-09 36.3 0.1 8.7e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EON99916.1 - 0.0018 17.7 0.1 0.0028 17.0 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NMT1 PF09084.11 EON99917.1 - 4.7e-80 268.6 0.0 6.4e-80 268.1 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EON99917.1 - 1.6e-06 28.0 0.0 0.13 12.0 0.0 3.7 3 1 1 4 4 4 2 NMT1-like family FMN_red PF03358.15 EON99917.1 - 0.16 11.7 0.1 0.41 10.4 0.1 1.6 1 0 0 1 1 1 0 NADPH-dependent FMN reductase PBP_like PF12727.7 EON99917.1 - 0.18 10.9 0.0 1.9 7.5 0.0 2.1 1 1 0 2 2 2 0 PBP superfamily domain MFS_1 PF07690.16 EON99918.1 - 6.1e-33 114.2 50.2 5.1e-27 94.7 36.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON99918.1 - 3.2e-10 39.5 35.5 0.0003 19.8 17.5 2.9 1 1 1 2 2 2 2 Sugar (and other) transporter DUF2304 PF10066.9 EON99918.1 - 0.44 10.8 4.7 0.75 10.0 3.8 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Acyl_transf_3 PF01757.22 EON99920.1 - 3.1e-15 56.1 22.9 3.8e-15 55.8 22.9 1.1 1 0 0 1 1 1 1 Acyltransferase family zf-H2C2 PF09337.10 EON99921.1 - 0.21 11.8 0.1 0.41 10.9 0.1 1.4 1 0 0 1 1 1 0 H2C2 zinc finger Abhydrolase_6 PF12697.7 EON99923.1 - 2.7e-08 34.7 0.5 5.1e-08 33.8 0.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 EON99923.1 - 2.5e-07 30.4 0.0 5.8e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF1100 PF06500.11 EON99923.1 - 8e-06 24.9 0.0 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) BAAT_C PF08840.11 EON99923.1 - 0.0001 22.3 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 EON99923.1 - 0.00014 21.5 0.1 0.00024 20.8 0.1 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 EON99923.1 - 0.00015 20.6 0.1 0.0029 16.3 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 EON99923.1 - 0.00026 20.5 0.0 0.00054 19.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EON99923.1 - 0.00067 19.0 0.0 0.0032 16.8 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EON99923.1 - 0.003 17.4 0.0 0.0045 16.8 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EON99923.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EON99923.1 - 0.017 15.2 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DHDPS PF00701.22 EON99924.1 - 2.6e-44 151.1 0.0 3e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 EON99924.1 - 0.027 13.9 0.1 0.05 13.1 0.1 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase ABC2_membrane PF01061.24 EON99925.1 - 5.3e-76 254.7 62.9 3.2e-41 141.1 28.3 3.7 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 EON99925.1 - 4.1e-35 119.5 9.6 3.7e-29 100.5 0.1 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 EON99925.1 - 3.7e-18 66.3 0.0 6.9e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EON99925.1 - 7.6e-05 22.0 18.9 7.6e-05 22.0 18.9 3.8 4 1 0 4 4 3 2 ABC-2 family transporter protein AAA_25 PF13481.6 EON99925.1 - 0.00021 21.0 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EON99925.1 - 0.00029 21.0 0.1 0.00054 20.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EON99925.1 - 0.00069 20.0 0.0 0.0014 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EON99925.1 - 0.0023 17.9 0.0 0.0053 16.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 EON99925.1 - 0.0074 16.8 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EON99925.1 - 0.0094 15.8 1.7 1.4 8.7 0.1 2.7 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON99925.1 - 0.01 15.3 0.0 0.057 12.8 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EON99925.1 - 0.012 15.4 0.2 0.028 14.2 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 EON99925.1 - 0.04 13.5 0.2 0.067 12.8 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2946 PF11162.8 EON99925.1 - 0.049 14.3 0.1 0.18 12.5 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) AAA_23 PF13476.6 EON99925.1 - 0.15 12.5 0.1 0.75 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EON99925.1 - 0.16 11.6 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EON99925.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Amidase PF01425.21 EON99926.1 - 2.5e-47 161.9 0.1 1.3e-29 103.5 0.0 3.0 1 1 1 2 2 2 2 Amidase Amidohydro_2 PF04909.14 EON99926.1 - 1.3e-25 90.8 0.3 6.5e-25 88.5 0.3 1.9 1 1 0 1 1 1 1 Amidohydrolase SBP_bac_11 PF13531.6 EON99926.1 - 0.01 15.6 0.2 0.021 14.6 0.2 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein MFS_1 PF07690.16 EON99927.1 - 3.3e-28 98.6 44.2 2.1e-27 96.0 43.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily PIP5K PF01504.18 EON99928.1 - 7.3e-25 87.7 0.0 1e-24 87.2 0.0 1.2 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Bac_DNA_binding PF00216.21 EON99928.1 - 0.16 12.2 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial DNA-binding protein CD225 PF04505.12 EON99929.1 - 0.031 14.4 0.5 0.064 13.4 0.5 1.4 1 0 0 1 1 1 0 Interferon-induced transmembrane protein DUF43 PF01861.16 EON99929.1 - 0.098 11.9 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Pam17 PF08566.10 EON99930.1 - 1.9e-66 223.0 0.0 2.5e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 BPD_transp_2 PF02653.16 EON99930.1 - 0.017 14.3 0.5 0.025 13.7 0.5 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component LIP PF03583.14 EON99931.1 - 6.9e-57 192.9 0.1 8.9e-57 192.6 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase YaeQ PF07152.12 EON99932.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 YaeQ protein BTB PF00651.31 EON99933.1 - 3.8e-07 30.3 0.0 7.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain FAD_binding_3 PF01494.19 EON99934.1 - 6.3e-22 78.3 0.1 8.4e-22 77.9 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EON99934.1 - 1.4e-05 24.5 0.1 0.12 11.5 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EON99934.1 - 0.0043 16.0 0.7 1.8 7.3 0.1 3.0 2 1 0 2 2 2 2 Tryptophan halogenase SE PF08491.10 EON99934.1 - 0.0043 16.1 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.6 EON99934.1 - 0.0045 17.2 0.1 0.011 16.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EON99934.1 - 0.0056 16.3 0.1 0.014 15.0 0.0 1.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON99934.1 - 0.0082 15.3 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EON99934.1 - 0.016 14.6 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EON99934.1 - 0.028 15.0 0.0 0.086 13.4 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON99934.1 - 0.038 13.1 0.6 0.12 11.5 0.6 1.8 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EON99934.1 - 0.043 13.2 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase RNF111_N PF15303.6 EON99935.1 - 0.089 12.5 4.7 2.1 8.0 1.0 2.2 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus Gly_transf_sug PF04488.15 EON99936.1 - 1.5e-13 51.1 0.1 3.2e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Pectate_lyase_3 PF12708.7 EON99937.1 - 1.5e-76 257.0 23.0 6.9e-72 241.8 12.0 3.6 3 0 0 3 3 3 3 Pectate lyase superfamily protein End_N_terminal PF12218.8 EON99937.1 - 0.063 13.0 1.2 0.21 11.3 0.3 2.3 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Epimerase PF01370.21 EON99939.1 - 7.8e-20 71.4 0.0 9.4e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EON99939.1 - 1.5e-10 40.6 0.0 1.9e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EON99939.1 - 8.8e-09 35.2 0.0 1.9e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EON99939.1 - 1.6e-06 27.5 0.0 2.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EON99939.1 - 0.00013 21.3 0.4 0.0031 16.7 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.25 EON99939.1 - 0.0071 15.8 0.0 0.033 13.6 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EON99939.1 - 0.069 12.3 0.0 0.26 10.4 0.0 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 EON99939.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.7 1 1 0 1 1 1 0 KR domain PTCRA PF15028.6 EON99942.1 - 0.044 13.5 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Pre-T-cell antigen receptor Peptidase_C48 PF02902.19 EON99943.1 - 8.9e-19 68.2 0.0 2.7e-18 66.6 0.0 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_S9 PF00326.21 EON99944.1 - 7.4e-45 153.0 0.0 1.1e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 EON99944.1 - 2.6e-07 29.8 0.0 3.7e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Esterase_phd PF10503.9 EON99944.1 - 0.01 15.3 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Esterase PF00756.20 EON99944.1 - 0.024 14.3 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 EON99944.1 - 0.035 13.4 0.1 0.44 9.8 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ank_2 PF12796.7 EON99945.1 - 8.5e-14 51.9 0.1 9.5e-06 26.1 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EON99945.1 - 3.1e-11 43.6 0.2 0.0069 16.9 0.0 5.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EON99945.1 - 2.6e-09 36.5 1.8 2.8e-05 24.1 0.0 5.2 5 1 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EON99945.1 - 6.4e-07 29.6 2.7 0.0014 19.0 0.0 4.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EON99945.1 - 4.2e-06 26.9 0.5 0.0044 17.3 0.1 3.7 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Glyco_hydro_2_N PF02837.18 EON99947.1 - 3.3e-12 46.7 0.1 1.4e-11 44.6 0.0 2.2 3 0 0 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 EON99947.1 - 5.9e-12 46.2 0.1 4.3e-10 40.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 EON99947.1 - 5.5e-10 38.8 0.0 1.3e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain MFS_1 PF07690.16 EON99948.1 - 1.5e-41 142.5 48.8 8e-41 140.1 48.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EON99948.1 - 4e-13 48.7 18.5 5.2e-13 48.3 18.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Spore_YhaL PF14147.6 EON99948.1 - 0.18 11.5 2.5 6.2 6.6 0.1 2.7 2 0 0 2 2 2 0 Sporulation protein YhaL SLX9 PF15341.6 EON99949.1 - 1.7e-39 135.2 3.8 2.3e-39 134.8 3.8 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 ThiF PF00899.21 EON99950.1 - 1.5e-26 93.3 0.3 2.1e-26 92.8 0.3 1.2 1 0 0 1 1 1 1 ThiF family ABC_tran_CTD PF16326.5 EON99950.1 - 0.0022 18.2 1.0 0.0041 17.3 1.0 1.4 1 0 0 1 1 1 1 ABC transporter C-terminal domain Shikimate_DH PF01488.20 EON99950.1 - 0.0026 17.8 0.4 0.0082 16.2 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Myosin_tail_1 PF01576.19 EON99950.1 - 0.012 13.5 0.5 0.014 13.3 0.5 1.0 1 0 0 1 1 1 0 Myosin tail Ldh_1_N PF00056.23 EON99950.1 - 0.027 14.6 0.3 1.7 8.7 0.2 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EON99950.1 - 0.031 13.5 1.9 0.043 13.0 1.9 1.2 1 0 0 1 1 1 0 FAD binding domain WHEP-TRS PF00458.20 EON99950.1 - 0.039 14.1 1.2 0.07 13.3 1.2 1.4 1 0 0 1 1 1 0 WHEP-TRS domain Pyr_redox PF00070.27 EON99950.1 - 0.076 13.6 0.7 0.14 12.8 0.7 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EON99950.1 - 0.15 11.7 1.1 0.23 11.1 1.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 EON99950.1 - 0.18 11.4 0.4 0.25 10.9 0.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 EON99950.1 - 0.22 10.8 3.3 0.06 12.6 0.7 1.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EON99950.1 - 0.24 10.5 1.4 0.34 9.9 1.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_4 PF01565.23 EON99951.1 - 4.5e-20 71.8 0.1 8.4e-20 70.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EON99951.1 - 1.2e-10 41.3 0.2 1.2e-10 41.3 0.2 2.1 2 0 0 2 2 2 1 Berberine and berberine like ALO PF04030.14 EON99951.1 - 0.0017 18.2 0.1 0.003 17.4 0.1 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Cytokin-bind PF09265.10 EON99951.1 - 0.034 13.5 0.4 0.055 12.9 0.4 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Glyco_hydro_28 PF00295.17 EON99952.1 - 6e-107 357.5 19.5 7.7e-107 357.1 19.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 EON99952.1 - 5.8e-06 26.3 32.8 9.6e-06 25.5 25.0 3.0 1 1 2 3 3 3 3 Right handed beta helix region DUF4558 PF15104.6 EON99953.1 - 0.0059 16.6 4.4 0.012 15.6 4.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4558) ALMT PF11744.8 EON99953.1 - 0.0081 15.0 7.6 0.011 14.6 7.6 1.1 1 0 0 1 1 1 1 Aluminium activated malate transporter DUF848 PF05852.11 EON99953.1 - 0.043 13.9 2.9 0.085 13.0 2.9 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) AAA_13 PF13166.6 EON99953.1 - 0.14 10.8 7.6 0.21 10.2 7.6 1.1 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 EON99953.1 - 0.45 9.8 6.8 0.65 9.3 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 EON99953.1 - 2 9.0 16.0 3.3 8.2 16.0 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region FAM76 PF16046.5 EON99953.1 - 3.4 6.9 10.8 8.3 5.7 10.0 1.7 1 1 0 1 1 1 0 FAM76 protein Muted PF14942.6 EON99953.1 - 4.3 7.7 10.3 10 6.5 10.3 1.7 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein FapA PF03961.13 EON99953.1 - 4.8 5.7 6.9 6.9 5.2 6.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A BATS PF06968.13 EON99954.1 - 8.5e-24 83.5 0.1 2.9e-23 81.8 0.1 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EON99954.1 - 4.9e-16 59.6 0.6 4.7e-15 56.4 0.2 2.3 3 0 0 3 3 3 1 Radical SAM superfamily HMGL-like PF00682.19 EON99954.1 - 0.087 12.4 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 HMGL-like Pectinesterase PF01095.19 EON99957.1 - 1.2e-39 135.9 7.7 1.5e-39 135.5 7.7 1.1 1 0 0 1 1 1 1 Pectinesterase Sugar_tr PF00083.24 EOO00001.1 - 1.2e-62 212.2 13.3 1.5e-62 212.0 13.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF983 PF06170.12 EOO00001.1 - 0.071 13.5 2.8 0.12 12.9 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF983) QRPTase_C PF01729.19 EOO00001.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain MIG-14_Wnt-bd PF06664.12 EOO00001.1 - 0.18 11.0 12.8 0.017 14.3 7.2 2.0 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Oxidored_q4 PF00507.19 EOO00001.1 - 1.8 8.8 6.7 1.4 9.1 3.0 2.6 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 AMP-binding PF00501.28 EOO00002.1 - 1.5e-85 287.4 0.0 1.8e-85 287.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Peptidase_S8 PF00082.22 EOO00002.1 - 0.043 13.1 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Subtilase family BCA_ABC_TP_C PF12399.8 EOO00002.1 - 0.57 10.2 3.5 0.31 11.0 0.3 2.3 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter Arm PF00514.23 EOO00003.1 - 1.5e-08 34.4 0.2 0.0071 16.4 0.0 3.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EOO00003.1 - 0.00011 22.2 0.8 4.2 7.9 0.1 4.7 4 0 0 4 4 4 2 HEAT repeat DDE_Tnp_2 PF04693.12 EOO00003.1 - 0.026 13.8 0.0 0.065 12.5 0.0 1.5 2 0 0 2 2 2 0 Archaeal putative transposase ISC1217 PUL PF08324.11 EOO00003.1 - 0.056 12.7 0.4 0.23 10.7 0.1 2.2 2 1 0 2 2 2 0 PUL domain HEAT_EZ PF13513.6 EOO00003.1 - 0.091 13.3 0.3 79 3.9 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat DUF3130 PF11328.8 EOO00003.1 - 0.16 12.2 0.0 0.51 10.6 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3130 zf-TRAF PF02176.18 EOO00004.1 - 9.1e-10 39.1 24.3 0.00068 20.3 7.3 4.4 1 1 3 4 4 4 4 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 EOO00004.1 - 1.1e-09 38.0 11.4 1.1e-09 38.0 11.4 3.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EOO00004.1 - 6.4e-09 35.7 11.4 1.1e-07 31.8 11.4 2.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EOO00004.1 - 6.1e-08 32.9 9.1 6.1e-08 32.9 9.1 4.0 1 1 3 4 4 3 2 Ring finger domain zf-C3HC4_3 PF13920.6 EOO00004.1 - 2.8e-07 30.3 6.8 2.8e-07 30.3 6.8 4.0 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EOO00004.1 - 4e-07 29.8 7.5 4e-07 29.8 7.5 3.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EOO00004.1 - 2.1e-05 24.4 9.1 2.1e-05 24.4 9.1 3.4 3 2 0 3 3 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EOO00004.1 - 8.6e-05 22.3 14.1 0.00053 19.8 11.5 3.1 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 EOO00004.1 - 0.00027 20.7 6.7 0.00027 20.7 6.7 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 EOO00004.1 - 0.00037 20.2 1.6 0.00037 20.2 1.6 4.1 5 0 0 5 5 4 1 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EOO00004.1 - 0.00083 19.4 9.4 0.00083 19.4 9.4 3.0 3 2 0 3 3 2 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 EOO00004.1 - 0.00087 19.5 6.4 0.00087 19.5 6.4 3.9 3 1 2 5 5 5 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EOO00004.1 - 0.0012 19.0 6.8 0.0012 19.0 6.8 3.7 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING Sina PF03145.16 EOO00004.1 - 0.0044 17.0 3.0 0.0044 17.0 3.0 2.6 2 1 0 2 2 2 1 Seven in absentia protein family AAA_32 PF13654.6 EOO00004.1 - 0.019 13.8 1.2 0.029 13.1 1.2 1.2 1 0 0 1 1 1 0 AAA domain Ran-binding PF05508.11 EOO00004.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 RanGTP-binding protein Sec1 PF00995.23 EOO00004.1 - 2.1 7.4 4.4 0.22 10.7 0.2 1.4 2 0 0 2 2 2 0 Sec1 family Mitofilin PF09731.9 EOO00004.1 - 2.3 7.0 6.9 3.5 6.3 6.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein zf-MIZ PF02891.20 EOO00004.1 - 3.2 7.6 10.0 59 3.5 9.5 3.1 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger Na_H_Exchanger PF00999.21 EOO00005.1 - 5e-40 137.5 16.8 7e-40 137.0 16.8 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DHHC PF01529.20 EOO00005.1 - 0.7 10.0 2.8 5.4 7.1 0.0 3.1 3 0 0 3 3 3 0 DHHC palmitoyltransferase GATase_2 PF00310.21 EOO00006.1 - 2.5e-182 606.3 0.0 3.6e-182 605.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EOO00006.1 - 7.1e-156 519.0 0.0 1.1e-155 518.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EOO00006.1 - 9.5e-111 369.7 0.0 1.2e-108 362.8 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EOO00006.1 - 1.4e-85 285.7 3.0 2.3e-85 285.0 3.0 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EOO00006.1 - 8.8e-24 84.2 0.9 7.3e-23 81.2 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EOO00006.1 - 2.8e-21 75.4 0.1 5.6e-21 74.4 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 EOO00006.1 - 1.2e-08 35.0 0.0 4.2e-08 33.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EOO00006.1 - 2.2e-08 34.1 0.6 0.00078 19.1 0.1 2.7 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EOO00006.1 - 3.4e-08 33.9 0.1 7.4e-05 23.2 0.0 3.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EOO00006.1 - 1.2e-06 28.1 0.2 2.8e-06 26.9 0.1 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EOO00006.1 - 2.3e-05 23.9 0.2 5e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EOO00006.1 - 4e-05 22.9 0.1 0.00031 20.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EOO00006.1 - 5.1e-05 22.1 0.1 5.1e-05 22.1 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.6 EOO00006.1 - 0.00012 22.5 0.1 1.2 9.6 0.0 3.0 3 0 0 3 3 2 2 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EOO00006.1 - 0.00069 19.0 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EOO00006.1 - 0.00088 18.6 0.0 0.18 11.1 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EOO00006.1 - 0.0011 18.3 0.7 0.2 10.9 0.0 3.0 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EOO00006.1 - 0.0021 17.4 0.3 0.014 14.7 0.1 2.3 2 0 0 2 2 2 1 Thi4 family NAD_Gly3P_dh_N PF01210.23 EOO00006.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 EOO00006.1 - 0.024 13.8 1.8 0.049 12.7 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EOO00006.1 - 0.025 13.6 0.1 0.29 10.1 0.1 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein FMN_dh PF01070.18 EOO00006.1 - 0.034 13.2 0.6 0.12 11.4 0.6 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase FMO-like PF00743.19 EOO00006.1 - 0.039 12.4 0.1 6.4 5.1 0.0 2.7 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like Allantoicase PF03561.15 EOO00007.1 - 2.9e-96 319.1 0.1 2.5e-47 160.5 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat 6PF2K PF01591.18 EOO00008.1 - 4.4e-62 209.3 0.0 2.2e-45 154.7 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EOO00008.1 - 4.2e-30 104.9 0.0 2.2e-24 86.3 0.0 2.7 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Sigma70_r4_2 PF08281.12 EOO00008.1 - 0.028 14.1 0.3 2 8.2 0.1 2.6 2 0 0 2 2 2 0 Sigma-70, region 4 Ank_5 PF13857.6 EOO00009.1 - 1.2e-11 44.5 0.4 1.3e-10 41.3 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EOO00009.1 - 3.7e-10 39.8 1.1 2.8e-05 24.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EOO00009.1 - 1.1e-08 35.5 0.0 5.5e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EOO00009.1 - 6e-07 29.9 0.2 1.7e-05 25.3 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) TIG PF01833.24 EOO00009.1 - 1.2e-06 28.5 0.1 4.8e-06 26.6 0.1 2.1 1 0 0 1 1 1 1 IPT/TIG domain Ank_3 PF13606.6 EOO00009.1 - 2.3e-05 24.4 0.6 0.024 15.1 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat FGGY_C PF02782.16 EOO00010.1 - 1.8e-49 168.2 1.0 2.7e-49 167.6 1.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EOO00010.1 - 3.6e-18 66.0 0.1 2e-14 53.7 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 EOO00010.1 - 0.2 11.5 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 Hexokinase Calcipressin PF04847.12 EOO00011.1 - 2.1e-53 180.9 0.2 2.8e-53 180.5 0.2 1.2 1 0 0 1 1 1 1 Calcipressin tRNA-synt_2d PF01409.20 EOO00012.1 - 1.9e-47 161.8 0.4 1.5e-23 83.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EOO00012.1 - 8.7e-28 96.6 0.0 1.8e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain PGG PF13962.6 EOO00013.1 - 0.39 10.6 5.1 0.28 11.0 2.8 1.8 1 1 0 1 1 1 0 Domain of unknown function DoxX PF07681.12 EOO00013.1 - 3.4 8.3 8.5 0.72 10.5 0.3 2.8 2 1 1 3 3 3 0 DoxX WD40 PF00400.32 EOO00014.1 - 0.00011 22.9 0.1 0.94 10.5 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat RabGAP-TBC PF00566.18 EOO00015.1 - 1e-50 172.4 0.0 1.6e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Porphobil_deamC PF03900.15 EOO00015.1 - 0.055 13.9 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 Porphobilinogen deaminase, C-terminal domain Sugar_tr PF00083.24 EOO00016.1 - 1.9e-102 343.5 20.7 2.3e-102 343.2 20.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO00016.1 - 9.7e-26 90.5 30.7 1.7e-25 89.7 23.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EOO00016.1 - 0.22 9.9 6.7 0.18 10.2 0.6 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2530 PF10745.9 EOO00016.1 - 0.77 10.0 4.5 2.8 8.2 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) TB2_DP1_HVA22 PF03134.19 EOO00016.1 - 2.2 8.3 6.9 0.29 11.1 2.1 2.1 2 0 0 2 2 2 0 TB2/DP1, HVA22 family RNA_pol_A_bac PF01000.26 EOO00017.1 - 1.6e-32 112.2 0.0 2.6e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EOO00017.1 - 5.8e-17 60.9 0.0 7.8e-17 60.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Cu_bind_like PF02298.17 EOO00019.1 - 0.016 15.2 0.1 0.082 12.9 0.1 2.1 1 1 0 1 1 1 0 Plastocyanin-like domain Fungal_trans_2 PF11951.8 EOO00020.1 - 0.0051 15.7 0.0 0.0073 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 EOO00022.1 - 1.1e-55 188.9 0.0 1.6e-55 188.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO00022.1 - 1.4e-30 106.4 0.0 4.5e-29 101.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EOO00022.1 - 0.01 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EOO00022.1 - 0.049 12.6 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Asp PF00026.23 EOO00023.1 - 6.5e-65 219.6 3.6 7.6e-65 219.4 3.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EOO00023.1 - 6.9e-13 49.2 2.2 5.3e-10 39.8 2.2 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EOO00023.1 - 0.029 14.2 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Nic96 PF04097.14 EOO00024.1 - 8.4e-225 747.9 0.0 1e-224 747.6 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Rad51 PF08423.11 EOO00025.1 - 3.7e-41 141.1 0.0 8e-38 130.2 0.0 2.1 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 EOO00025.1 - 2.7e-08 33.6 0.0 5.7e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 EOO00025.1 - 3.8e-07 29.8 0.2 0.00025 20.6 0.0 2.0 2 0 0 2 2 2 2 recA bacterial DNA recombination protein ATPase PF06745.13 EOO00025.1 - 3.1e-05 23.4 0.0 5.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 KaiC Pox_A32 PF04665.12 EOO00025.1 - 0.11 11.9 0.2 0.2 11.1 0.2 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.6 EOO00025.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain Bac_rhodopsin PF01036.18 EOO00026.1 - 1.7e-26 93.2 26.8 2.3e-26 92.8 26.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Cpn60_TCP1 PF00118.24 EOO00027.1 - 6e-171 569.4 1.8 6.8e-171 569.2 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 EOO00027.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 BRK domain GRAB PF10375.9 EOO00028.1 - 1.2e-08 34.5 0.0 2.5e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain CENP-F_leu_zip PF10473.9 EOO00028.1 - 2.1e-06 27.8 60.1 0.0017 18.4 17.2 4.0 2 1 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 EOO00028.1 - 5.1e-05 23.0 54.2 0.021 14.4 28.8 2.6 1 1 1 2 2 2 2 Intermediate filament protein Myosin_tail_1 PF01576.19 EOO00028.1 - 0.00045 18.2 54.4 0.0072 14.2 25.8 2.1 1 1 1 2 2 2 2 Myosin tail GAS PF13851.6 EOO00028.1 - 0.0019 17.6 12.7 0.0019 17.6 12.7 4.5 2 1 2 4 4 4 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EOO00028.1 - 0.0021 17.0 25.5 0.0021 17.0 25.5 3.1 1 1 2 3 3 3 2 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 EOO00028.1 - 0.014 15.7 11.2 0.014 15.7 11.2 5.4 1 1 5 6 6 6 0 ABC transporter C-terminal domain FPP PF05911.11 EOO00028.1 - 0.015 13.5 47.4 0.0053 15.0 24.2 2.3 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil TPR_MLP1_2 PF07926.12 EOO00028.1 - 0.016 15.3 9.8 0.016 15.3 9.8 5.6 2 1 2 5 5 5 0 TPR/MLP1/MLP2-like protein DUF4618 PF15397.6 EOO00028.1 - 0.028 13.8 40.6 0.087 12.2 27.4 3.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) Golgin_A5 PF09787.9 EOO00028.1 - 0.037 13.5 55.8 1.4 8.3 21.4 3.9 1 1 3 4 4 4 0 Golgin subfamily A member 5 DUF1664 PF07889.12 EOO00028.1 - 0.092 12.8 27.3 0.87 9.6 2.5 4.2 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EOO00028.1 - 0.27 11.3 16.0 1.1 9.3 1.1 3.7 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 EOO00028.1 - 0.32 8.9 22.1 0.063 11.2 13.9 2.3 1 1 1 2 2 2 0 Prominin HicB_lk_antitox PF15919.5 EOO00028.1 - 0.43 10.7 4.5 0.18 11.9 0.4 2.4 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system Nup54_57_C PF18570.1 EOO00028.1 - 0.54 9.9 0.0 0.54 9.9 0.0 5.1 5 0 0 5 5 5 0 NUP57/Nup54 C-terminal domain DUF2935 PF11155.8 EOO00028.1 - 0.71 10.2 7.3 4 7.8 3.0 3.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF641 PF04859.12 EOO00028.1 - 1.2 9.4 37.8 1.9 8.8 8.3 4.0 2 1 1 4 4 4 0 Plant protein of unknown function (DUF641) NPV_P10 PF05531.12 EOO00028.1 - 1.9 9.0 18.6 15 6.1 1.1 4.9 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 EOO00028.1 - 2.6 8.2 28.6 4.9 7.3 3.3 4.1 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family SHE3 PF17078.5 EOO00028.1 - 5.3 6.7 37.4 4.1 7.0 21.5 3.8 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 Rootletin PF15035.6 EOO00028.1 - 9.3 6.2 53.6 0.018 15.1 20.9 3.6 2 2 1 3 3 2 0 Ciliary rootlet component, centrosome cohesion Tup_N PF08581.10 EOO00028.1 - 9.3 6.6 34.7 0.048 14.0 1.7 5.3 4 1 1 5 5 5 0 Tup N-terminal MAD PF05557.13 EOO00028.1 - 9.6 4.4 53.0 1.9 6.8 27.1 2.3 1 1 1 2 2 2 0 Mitotic checkpoint protein Cys_Met_Meta_PP PF01053.20 EOO00029.1 - 8.2e-152 505.2 0.0 9.3e-152 505.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EOO00029.1 - 1.4e-10 40.9 0.0 3.2e-10 39.7 0.1 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EOO00029.1 - 1.4e-10 41.0 0.2 2.3e-10 40.3 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EOO00029.1 - 3e-09 36.3 0.3 5.1e-09 35.6 0.3 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EOO00029.1 - 1.8e-07 30.7 0.0 2.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 EOO00029.1 - 0.00014 20.5 0.1 0.00019 20.1 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Asparaginase_C PF17763.1 EOO00029.1 - 0.0055 16.9 0.2 0.035 14.3 0.0 2.3 2 1 1 3 3 3 1 Glutaminase/Asparaginase C-terminal domain GDC-P PF02347.16 EOO00029.1 - 0.0091 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Ribosomal_60s PF00428.19 EOO00029.1 - 2.2 8.9 6.8 1 10.0 1.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_M13 PF01431.21 EOO00030.1 - 5.8e-60 202.4 1.0 8.5e-60 201.9 1.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 EOO00030.1 - 6.1e-41 141.4 0.0 8e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Ssl1 PF04056.14 EOO00031.1 - 4e-72 242.1 0.0 5.3e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EOO00031.1 - 4.6e-16 58.8 8.4 4.6e-16 58.8 8.4 3.4 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 EOO00031.1 - 1.2e-15 58.1 0.0 3.8e-15 56.5 0.0 1.8 2 1 1 3 3 3 1 von Willebrand factor type A domain Tfb4 PF03850.14 EOO00031.1 - 0.079 12.4 3.4 0.15 11.5 3.4 1.4 1 0 0 1 1 1 0 Transcription factor Tfb4 zinc_ribbon_15 PF17032.5 EOO00031.1 - 9.9 7.0 13.1 0.74 10.6 3.5 2.6 1 1 1 2 2 2 0 zinc-ribbon family Aldolase_II PF00596.21 EOO00032.1 - 2.1e-42 145.1 0.9 2.9e-42 144.7 0.9 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Ufd2P_core PF10408.9 EOO00033.1 - 7.7e-221 735.0 6.4 9.5e-221 734.7 6.4 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EOO00033.1 - 4.7e-23 81.1 0.6 1.6e-22 79.4 0.6 2.0 1 0 0 1 1 1 1 U-box domain Glyoxalase PF00903.25 EOO00034.1 - 1.9e-16 60.5 0.0 6.9e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EOO00034.1 - 5.6e-09 36.2 0.0 0.0048 17.2 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EOO00034.1 - 8.2e-05 22.8 0.0 0.46 10.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 EOO00034.1 - 0.00052 20.2 0.0 0.00095 19.4 0.0 1.4 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Pkinase PF00069.25 EOO00035.1 - 2.1e-09 37.2 0.0 3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO00035.1 - 0.0074 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Citrate_synt PF00285.21 EOO00036.1 - 1e-101 340.6 0.0 1.4e-101 340.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 EOO00036.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone Sec6 PF06046.13 EOO00037.1 - 1.1e-177 592.0 11.8 1.5e-177 591.5 11.8 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 EOO00037.1 - 2.3e-05 23.5 5.0 2.3e-05 23.5 5.0 2.8 4 0 0 4 4 4 1 Vps53-like, N-terminal Sec20 PF03908.13 EOO00037.1 - 0.16 11.9 2.7 0.52 10.3 0.5 3.0 2 1 1 3 3 3 0 Sec20 FAD_binding_2 PF00890.24 EOO00037.1 - 0.22 10.6 0.1 0.66 9.0 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain DUF1664 PF07889.12 EOO00037.1 - 0.86 9.6 5.4 1.8 8.6 1.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Vps54_N PF10475.9 EOO00037.1 - 1.9 7.7 8.0 1.6 7.9 2.7 2.5 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Myb_DNA-bind_3 PF12776.7 EOO00037.1 - 2.8 9.0 6.4 84 4.2 0.0 4.9 6 0 0 6 6 6 0 Myb/SANT-like DNA-binding domain DIL PF01843.19 EOO00038.1 - 5e-32 110.3 0.3 1.2e-31 109.1 0.3 1.7 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 EOO00038.1 - 6.9e-19 68.2 0.0 7.3e-12 45.7 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EOO00038.1 - 9.2e-10 38.9 0.3 6.2e-05 23.5 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EOO00038.1 - 1.2e-08 35.0 0.0 0.0021 18.3 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EOO00038.1 - 1.6e-08 34.6 0.1 0.012 16.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EOO00038.1 - 1.8e-06 27.8 0.0 0.074 13.6 0.0 4.1 3 0 0 3 3 3 1 Ankyrin repeat HSP70 PF00012.20 EOO00039.1 - 9e-09 34.1 0.1 6.1e-08 31.3 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein FtsA PF14450.6 EOO00039.1 - 0.018 15.5 0.1 0.17 12.3 0.1 2.3 2 0 0 2 2 2 0 Cell division protein FtsA DUF4618 PF15397.6 EOO00041.1 - 0.0014 18.2 2.4 0.002 17.6 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Golgin_A5 PF09787.9 EOO00041.1 - 0.0016 18.0 6.5 0.0022 17.5 6.5 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Lebercilin PF15619.6 EOO00041.1 - 0.0036 17.0 11.2 0.12 12.0 1.9 2.1 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 EOO00041.1 - 0.0077 15.1 9.3 0.01 14.8 9.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein IFT57 PF10498.9 EOO00041.1 - 0.015 14.3 2.8 0.022 13.8 2.8 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 ADIP PF11559.8 EOO00041.1 - 0.022 14.9 6.0 0.037 14.1 6.0 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Lectin_N PF03954.14 EOO00041.1 - 0.035 13.9 1.1 0.055 13.2 1.1 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain SPX PF03105.19 EOO00041.1 - 0.086 12.7 9.0 0.13 12.1 9.0 1.3 1 0 0 1 1 1 0 SPX domain Csm1_N PF18504.1 EOO00041.1 - 0.14 12.6 0.3 0.14 12.6 0.3 3.1 2 1 1 3 3 3 0 Csm1 N-terminal domain Phage_GP20 PF06810.11 EOO00041.1 - 0.14 11.9 0.2 0.14 11.9 0.2 1.7 2 0 0 2 2 2 0 Phage minor structural protein GP20 End3 PF12761.7 EOO00041.1 - 0.15 12.3 5.6 0.25 11.5 5.6 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF4200 PF13863.6 EOO00041.1 - 0.34 11.3 9.7 0.46 10.9 8.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF745 PF05335.13 EOO00041.1 - 0.55 9.9 10.1 0.99 9.1 10.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF2968 PF11180.8 EOO00041.1 - 0.84 9.2 10.7 0.11 12.1 5.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) PKcGMP_CC PF16808.5 EOO00041.1 - 1.3 9.0 17.4 0.42 10.5 0.6 3.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 EOO00041.1 - 1.5 9.5 8.4 2.1 9.0 0.1 3.3 1 1 2 3 3 3 0 SlyX ATG16 PF08614.11 EOO00041.1 - 1.7 8.8 19.0 16 5.6 19.0 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 EOO00041.1 - 2 8.7 10.1 7 6.9 10.1 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 EOO00041.1 - 2.5 8.6 11.8 4.6 7.8 11.7 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF641 PF04859.12 EOO00041.1 - 7.2 7.0 9.4 96 3.3 6.5 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Apc15p PF05841.11 EOO00042.1 - 1.4e-19 71.2 0.7 1.4e-19 71.2 0.7 3.4 3 1 0 3 3 3 1 Apc15p protein DUF1168 PF06658.12 EOO00044.1 - 1.6e-38 131.6 9.0 2.3e-38 131.1 9.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) MRP-S26 PF14943.6 EOO00044.1 - 0.25 11.3 9.8 0.35 10.7 9.8 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Complex1_LYR PF05347.15 EOO00045.1 - 0.005 16.9 0.5 0.005 16.9 0.5 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EOO00045.1 - 0.11 13.3 3.8 0.26 12.1 3.8 1.8 1 1 0 1 1 1 0 Complex1_LYR-like Chs7 PF12271.8 EOO00046.1 - 8.6e-95 317.4 14.0 1e-94 317.1 14.0 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF4059 PF13268.6 EOO00046.1 - 0.034 14.6 10.1 0.044 14.2 0.2 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4059) Ribosomal_L15e PF00827.17 EOO00047.1 - 1e-89 299.4 11.0 1.2e-89 299.1 11.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 IKI3 PF04762.12 EOO00048.1 - 8.5e-234 778.6 0.0 1.3e-155 519.9 0.0 2.1 1 1 1 2 2 2 2 IKI3 family ANAPC4_WD40 PF12894.7 EOO00048.1 - 0.0037 17.5 0.4 1.3e+02 2.9 0.0 5.5 4 1 2 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 EOO00048.1 - 0.0084 16.1 5.8 0.42 10.8 0.3 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EOO00048.1 - 0.2 11.5 1.8 0.57 10.1 0.3 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EOO00048.1 - 0.47 10.6 4.4 1.1 9.5 0.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat RabGAP-TBC PF00566.18 EOO00049.1 - 2.3e-34 119.0 0.0 3.7e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Sororin PF09666.10 EOO00049.1 - 0.073 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Sororin protein DUF3984 PF13136.6 EOO00050.1 - 4.1e-25 88.9 6.8 1.6e-24 87.0 3.4 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3984) PAC1 PF16094.5 EOO00050.1 - 0.15 11.2 0.1 0.24 10.5 0.1 1.3 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 His_Phos_1 PF00300.22 EOO00051.1 - 5e-27 94.9 0.0 1.2e-26 93.6 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) P5-ATPase PF12409.8 EOO00051.1 - 0.056 13.5 0.0 0.056 13.5 0.0 1.8 2 0 0 2 2 2 0 P5-type ATPase cation transporter PUF PF00806.19 EOO00052.1 - 9.6e-60 195.1 12.6 7.9e-08 31.6 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF2012 PF09430.10 EOO00053.1 - 2.3e-23 82.6 0.0 3.1e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CAP_GLY PF01302.25 EOO00054.1 - 2.3e-21 75.6 1.4 4e-21 74.8 1.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain T6_Ig_like PF18002.1 EOO00054.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 T6 antigen Ig like domain Cytochrom_B561 PF03188.16 EOO00055.1 - 1.3e-17 64.3 3.2 1.3e-17 64.3 3.2 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4271 PF14093.6 EOO00055.1 - 0.0041 17.1 5.7 0.0041 17.1 5.7 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4271) SLATT_3 PF18184.1 EOO00055.1 - 0.16 12.1 0.4 1.3 9.1 0.2 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 DUF1774 PF08611.10 EOO00055.1 - 6.8 7.1 9.2 1.2 9.5 0.7 2.9 2 1 1 3 3 3 0 Fungal protein of unknown function (DUF1774) DUF2162 PF09930.9 EOO00055.1 - 8.5 5.7 14.0 0.51 9.7 5.0 2.5 1 1 1 2 2 2 0 Predicted transporter (DUF2162) YabA PF06156.13 EOO00056.1 - 2.3 8.9 7.7 4.1 8.1 1.6 2.3 1 1 1 2 2 2 0 Initiation control protein YabA RNA_pol_Rpb2_6 PF00562.28 EOO00057.1 - 8.4e-121 403.7 0.0 1.3e-120 403.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EOO00057.1 - 1.6e-53 181.2 0.1 2.8e-53 180.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EOO00057.1 - 8.8e-33 112.6 0.7 2e-32 111.4 0.7 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EOO00057.1 - 1.4e-28 99.8 0.2 3.6e-28 98.5 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EOO00057.1 - 3.3e-22 78.5 0.3 8.4e-22 77.2 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EOO00057.1 - 1.7e-20 72.9 0.0 3.5e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EOO00057.1 - 2.6e-12 47.1 0.4 8.4e-12 45.5 0.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 zf-RING_2 PF13639.6 EOO00058.1 - 3.2e-10 40.2 3.0 5.3e-10 39.5 3.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EOO00058.1 - 6.8e-10 38.5 3.2 1.2e-09 37.7 3.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EOO00058.1 - 7.6e-06 25.7 2.3 1.3e-05 24.9 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EOO00058.1 - 3.1e-05 23.8 2.1 5.3e-05 23.0 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EOO00058.1 - 6.4e-05 23.2 4.2 0.00021 21.5 4.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EOO00058.1 - 0.0062 16.5 1.3 0.011 15.7 1.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EOO00058.1 - 0.02 14.9 5.0 0.038 14.0 5.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DUF5305 PF17231.2 EOO00058.1 - 0.027 13.9 1.6 0.042 13.2 0.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Prok-RING_4 PF14447.6 EOO00058.1 - 0.056 13.3 4.2 0.11 12.4 4.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 EOO00058.1 - 0.26 11.3 2.5 0.59 10.1 2.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.29 EOO00058.1 - 2.1 8.3 4.6 7.4 6.5 3.8 2.1 1 1 1 2 2 2 0 PHD-finger HATPase_c PF02518.26 EOO00059.1 - 3.1e-26 92.1 0.2 6.2e-26 91.1 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EOO00059.1 - 3.6e-22 78.6 0.3 1.1e-20 73.9 0.0 2.6 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EOO00059.1 - 3.2e-20 71.9 0.1 7.8e-20 70.7 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain BRCC36_C PF18110.1 EOO00059.1 - 0.12 12.5 0.1 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 BRCC36 C-terminal helical domain CTD_bind PF04818.13 EOO00060.1 - 1e-09 39.1 0.0 2e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 EOO00060.1 - 5.2e-06 26.2 0.0 9.9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 EOO00061.1 - 1.6e-28 98.5 5.2 1.4e-12 47.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TrbC PF04956.13 EOO00061.1 - 0.1 12.8 1.0 0.47 10.7 0.1 2.4 3 0 0 3 3 3 0 TrbC/VIRB2 family GFO_IDH_MocA PF01408.22 EOO00062.1 - 6.2e-18 65.8 0.5 1.2e-17 64.8 0.5 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EOO00062.1 - 0.00021 21.9 0.2 0.00034 21.2 0.2 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EOO00062.1 - 0.084 13.5 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Use1 PF09753.9 EOO00063.1 - 8.6e-05 22.4 0.0 9.4e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 Hpt PF01627.23 EOO00064.1 - 5.8e-12 45.7 0.1 8.9e-12 45.1 0.1 1.4 1 1 0 1 1 1 1 Hpt domain DUF3425 PF11905.8 EOO00065.1 - 9.1e-23 80.6 0.5 1.3e-22 80.1 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) F-box-like PF12937.7 EOO00066.1 - 0.014 15.3 2.1 0.015 15.2 0.1 2.2 2 0 0 2 2 2 0 F-box-like Baculo_VP91_N PF08475.10 EOO00066.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal Aa_trans PF01490.18 EOO00067.1 - 1e-71 241.8 28.5 1.3e-71 241.5 28.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SMN PF06003.12 EOO00068.1 - 2.2e-05 23.9 4.3 0.0013 18.0 0.4 2.4 2 1 1 3 3 3 2 Survival motor neuron protein (SMN) Cementoin PF10511.9 EOO00068.1 - 0.048 13.9 3.0 0.2 12.0 0.0 2.6 2 0 0 2 2 2 0 Trappin protein transglutaminase binding domain TPT PF03151.16 EOO00069.1 - 1.2e-25 90.5 25.0 1.5e-25 90.1 25.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EOO00069.1 - 0.017 15.3 39.0 0.086 13.0 13.4 2.6 3 0 0 3 3 3 0 EamA-like transporter family UAA PF08449.11 EOO00069.1 - 0.033 13.4 25.1 0.051 12.8 25.1 1.2 1 0 0 1 1 1 0 UAA transporter family RFC1 PF08519.12 EOO00070.1 - 5.8e-55 185.8 0.1 2.5e-54 183.7 0.0 2.1 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EOO00070.1 - 4.3e-14 52.6 0.0 1.1e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EOO00070.1 - 4.2e-09 36.9 0.0 1.1e-08 35.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EOO00070.1 - 1.2e-07 31.9 0.0 2.9e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 EOO00070.1 - 0.0017 18.9 0.1 0.0091 16.5 0.1 2.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EOO00070.1 - 0.0025 18.1 0.0 0.013 15.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EOO00070.1 - 0.0048 17.3 0.6 0.014 15.8 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EOO00070.1 - 0.0051 16.5 0.1 0.0051 16.5 0.1 2.2 2 1 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 EOO00070.1 - 0.0096 15.7 0.0 0.025 14.3 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase III, delta subunit PTCB-BRCT PF12738.7 EOO00070.1 - 0.017 15.1 0.0 0.057 13.4 0.0 1.9 1 0 0 1 1 1 0 twin BRCT domain RuvB_N PF05496.12 EOO00070.1 - 0.037 13.8 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EOO00070.1 - 0.038 14.0 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EOO00070.1 - 0.056 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EOO00070.1 - 0.066 13.5 1.8 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EOO00070.1 - 0.066 13.4 0.0 0.066 13.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 EOO00070.1 - 0.085 12.8 0.0 3.2 7.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 EOO00070.1 - 0.15 11.9 0.1 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 NTPase LtrA PF06772.11 EOO00072.1 - 4.7e-23 82.0 3.6 4.7e-23 82.0 3.6 1.9 1 1 1 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) Cucumo_2B PF03263.13 EOO00073.1 - 0.058 13.9 0.3 0.19 12.2 0.0 1.9 2 0 0 2 2 2 0 Cucumovirus protein 2B Aldo_ket_red PF00248.21 EOO00074.1 - 7.8e-12 45.0 0.0 1.1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_cc PF11790.8 EOO00075.1 - 3.8e-54 183.8 0.3 3.8e-54 183.8 0.3 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core AKAP7_NLS PF10469.9 EOO00076.1 - 1.6e-15 57.5 0.0 1.8e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Mito_carr PF00153.27 EOO00077.1 - 3.2e-50 168.0 0.5 3.4e-17 62.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EOO00077.1 - 0.052 12.7 0.4 2.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Gammaproteobacterial serine protease CHZ PF09649.10 EOO00079.1 - 5.7e-15 54.5 2.7 5.7e-15 54.5 2.7 2.6 3 0 0 3 3 3 1 Histone chaperone domain CHZ BUD22 PF09073.10 EOO00079.1 - 4.5 6.5 27.2 5.1 6.3 27.2 1.0 1 0 0 1 1 1 0 BUD22 E1-E2_ATPase PF00122.20 EOO00080.1 - 8.9e-50 168.7 4.7 8.9e-50 168.7 4.7 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EOO00080.1 - 2.6e-17 63.8 0.0 9.1e-17 62.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EOO00080.1 - 3.4e-11 42.7 0.0 8.1e-11 41.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EOO00080.1 - 0.0019 18.0 0.1 0.0046 16.7 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EOO00080.1 - 0.006 16.6 0.1 0.017 15.2 0.0 1.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Methyltransf_11 PF08241.12 EOO00081.1 - 7.4e-11 42.6 0.1 6e-10 39.7 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO00081.1 - 1.8e-09 38.1 0.2 2e-07 31.6 0.2 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO00081.1 - 1.9e-08 34.9 0.0 5.7e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EOO00081.1 - 9.5e-06 25.5 0.0 3.2e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO00081.1 - 0.00018 21.4 0.1 0.036 13.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain DUF4024 PF13216.6 EOO00081.1 - 0.18 11.7 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) PAPA-1 PF04795.12 EOO00081.1 - 0.3 11.9 6.7 0.64 10.9 0.0 2.7 3 0 0 3 3 3 0 PAPA-1-like conserved region RNase_H PF00075.24 EOO00082.1 - 4.4e-35 120.9 0.1 6.8e-35 120.3 0.1 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 EOO00082.1 - 1.3e-34 118.2 8.5 2.2e-17 63.1 0.3 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin KOW PF00467.29 EOO00083.1 - 1.6e-05 24.6 0.2 3.2e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 KOW motif Myb_DNA-bind_5 PF13873.6 EOO00083.1 - 6.6 6.9 8.9 2.3 8.3 2.1 2.9 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Mito_carr PF00153.27 EOO00084.1 - 1.7e-41 140.1 6.8 7.1e-16 57.9 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L27e PF01777.18 EOO00085.1 - 5.8e-37 125.9 4.8 8.2e-37 125.4 4.8 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EOO00085.1 - 0.0087 16.0 1.9 0.024 14.6 1.9 1.8 1 0 0 1 1 1 1 KOW motif VTC PF09359.10 EOO00086.1 - 7.6e-90 301.0 0.9 1.5e-89 300.1 0.9 1.5 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 EOO00086.1 - 3.6e-12 46.5 2.9 7.5e-12 45.5 2.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 EOO00086.1 - 7.2e-08 32.8 2.8 0.00032 20.7 0.0 4.3 3 1 2 5 5 5 2 SPX domain DUF1993 PF09351.10 EOO00086.1 - 0.056 13.6 0.2 0.16 12.1 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Lebercilin PF15619.6 EOO00086.1 - 0.06 13.0 1.5 0.16 11.6 1.5 1.6 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease U62_UL91 PF17442.2 EOO00086.1 - 0.88 9.6 3.3 1.1 9.3 0.1 2.5 3 0 0 3 3 3 0 Functional domain of U62 and UL91 proteins bZIP_2 PF07716.15 EOO00086.1 - 2.8 8.1 5.2 18 5.5 0.5 2.9 3 0 0 3 3 3 0 Basic region leucine zipper WW PF00397.26 EOO00087.1 - 2.4e-09 37.1 7.0 4.5e-09 36.2 7.0 1.5 1 0 0 1 1 1 1 WW domain Amino_oxidase PF01593.24 EOO00088.1 - 3.1e-06 26.8 0.0 6.2e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EOO00088.1 - 8.2e-06 26.0 0.0 1.9e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 EOO00088.1 - 0.01 16.1 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 EOO00088.1 - 0.014 14.7 0.1 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 EOO00088.1 - 0.042 13.1 0.1 0.56 9.4 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EOO00088.1 - 0.17 11.1 0.1 0.32 10.2 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EOO00088.1 - 0.2 11.0 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase CFIA_Pcf11 PF11526.8 EOO00089.1 - 3.2e-07 30.7 1.9 1.5e-06 28.5 1.9 2.0 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 zf_UBZ PF18439.1 EOO00089.1 - 0.18 11.4 8.1 0.83 9.3 3.3 2.9 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-RRN7 PF11781.8 EOO00089.1 - 0.42 10.3 2.2 1.6 8.5 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C2HC_2 PF13913.6 EOO00089.1 - 0.97 9.4 4.6 4 7.4 1.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 EOO00089.1 - 1.3 10.0 8.9 1.2 10.1 0.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Sugar_tr PF00083.24 EOO00090.1 - 1.9e-106 356.7 17.6 2.3e-106 356.4 17.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO00090.1 - 1.3e-23 83.5 30.7 1.3e-23 83.5 30.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EOO00091.1 - 7.2e-18 64.6 19.6 9e-18 64.3 19.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily GrpE PF01025.19 EOO00092.1 - 5.5e-47 159.5 7.6 7e-47 159.2 7.6 1.1 1 0 0 1 1 1 1 GrpE RTT107_BRCT_6 PF16771.5 EOO00092.1 - 0.036 14.2 0.0 0.087 13.0 0.0 1.7 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain DUF1104 PF06518.11 EOO00092.1 - 0.27 11.6 7.3 1.1 9.7 7.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1104) Velvet PF11754.8 EOO00094.1 - 8.6e-55 186.4 0.0 1.1e-35 123.8 0.0 3.4 2 2 1 3 3 3 2 Velvet factor Ras PF00071.22 EOO00095.1 - 4.6e-56 188.9 0.0 5.3e-56 188.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EOO00095.1 - 8.2e-22 77.7 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EOO00095.1 - 4.3e-07 29.5 0.0 6.9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EOO00095.1 - 0.0016 17.9 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 EOO00095.1 - 0.051 12.7 0.1 0.47 9.6 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain baeRF_family3 PF18845.1 EOO00095.1 - 0.12 12.7 0.0 0.47 10.7 0.0 1.8 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 Gtr1_RagA PF04670.12 EOO00095.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Skp1 PF01466.19 EOO00095.1 - 0.23 11.6 0.8 1.2 9.3 0.1 2.4 3 0 0 3 3 3 0 Skp1 family, dimerisation domain MARVEL PF01284.23 EOO00096.1 - 1.9e-17 63.7 16.8 2.3e-17 63.3 16.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain Peptidase_M3 PF01432.20 EOO00098.1 - 6.2e-71 240.0 5.9 7.4e-44 150.8 0.5 2.1 1 1 1 2 2 2 2 Peptidase family M3 RE_SinI PF09570.10 EOO00098.1 - 0.19 10.9 0.3 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 SinI restriction endonuclease MFS_1 PF07690.16 EOO00099.1 - 2.2e-30 105.8 28.2 2.2e-30 105.8 28.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Epimerase PF01370.21 EOO00100.1 - 1.2e-08 34.7 0.1 2.2e-08 33.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EOO00100.1 - 6.3e-06 26.2 0.1 1.2e-05 25.3 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EOO00100.1 - 0.00042 19.8 0.2 0.003 17.1 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 EOO00100.1 - 0.0017 18.0 0.2 0.0033 17.0 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 EOO00100.1 - 0.0018 17.4 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EOO00100.1 - 0.0062 15.7 0.0 0.009 15.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EOO00100.1 - 0.025 14.5 0.2 0.094 12.6 0.2 1.8 1 1 0 1 1 1 0 KR domain CAP PF00188.26 EOO00101.1 - 2.2e-17 64.0 0.5 3.4e-17 63.4 0.5 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Bys1 PF04681.12 EOO00102.1 - 5.4e-13 49.2 0.2 1.7e-12 47.5 0.2 1.8 1 1 0 1 1 1 1 Blastomyces yeast-phase-specific protein p450 PF00067.22 EOO00103.1 - 2.3e-38 132.1 0.0 2.8e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1481 PF07356.12 EOO00106.1 - 0.094 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) CLP1_P PF16575.5 EOO00107.1 - 8.5e-33 113.7 0.0 1.3e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 EOO00107.1 - 9.2e-30 102.7 0.0 1.6e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 EOO00107.1 - 5.4e-26 91.3 0.0 9.6e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 EOO00107.1 - 0.00014 21.7 0.0 0.00055 19.8 0.1 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EOO00107.1 - 0.0098 16.3 0.1 0.027 14.8 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EOO00107.1 - 0.011 15.7 0.0 2.3 8.1 0.0 2.5 3 0 0 3 3 3 0 RsgA GTPase MMR_HSR1 PF01926.23 EOO00107.1 - 0.039 14.0 0.0 0.25 11.4 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 EOO00107.1 - 0.061 13.1 0.0 7.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 EOO00107.1 - 0.074 13.1 0.0 6 6.9 0.0 2.2 2 0 0 2 2 2 0 Dynamin family SRPRB PF09439.10 EOO00107.1 - 0.094 12.1 0.1 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EOO00107.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EOO00107.1 - 0.2 11.2 0.0 0.85 9.1 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.6 EOO00107.1 - 0.23 11.1 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain LapD_MoxY_N PF16448.5 EOO00108.1 - 0.02 14.8 0.1 1.2 9.0 0.0 3.8 2 1 0 3 3 3 0 LapD/MoxY periplasmic domain tRNA-synt_2 PF00152.20 EOO00111.1 - 5.2e-76 255.7 0.0 8.2e-76 255.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 EOO00111.1 - 3.7e-21 75.4 0.0 6e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 EOO00111.1 - 4e-05 23.5 0.0 9.6e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EOO00111.1 - 0.02 14.4 0.0 4.4 6.7 0.1 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF3786 PF12654.7 EOO00111.1 - 0.17 11.5 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Ribosomal_L1 PF00687.21 EOO00112.1 - 1.2e-63 214.5 2.6 1.2e-63 214.5 2.6 2.1 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family LRAT PF04970.13 EOO00112.1 - 0.49 10.7 3.3 0.52 10.6 0.0 2.6 3 1 0 3 3 3 0 Lecithin retinol acyltransferase CDC45 PF02724.14 EOO00112.1 - 2.7 6.2 22.3 4.3 5.5 22.3 1.3 1 0 0 1 1 1 0 CDC45-like protein ADH_zinc_N_2 PF13602.6 EOO00113.1 - 1.3e-18 68.4 0.0 1.5e-18 68.1 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EOO00113.1 - 1.5e-09 37.9 0.0 2.1e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Transp_cyt_pur PF02133.15 EOO00114.1 - 8.1e-156 519.2 31.1 9.4e-156 519.0 31.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 EOO00115.1 - 0.01 14.8 1.3 0.012 14.5 1.3 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily HA2 PF04408.23 EOO00116.1 - 4.3e-23 81.7 0.1 4.3e-23 81.7 0.1 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EOO00116.1 - 3.3e-21 75.4 0.0 6.7e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EOO00116.1 - 2e-13 50.6 0.0 6.6e-13 49.0 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain S1 PF00575.23 EOO00116.1 - 3.9e-10 39.9 0.8 1.1e-09 38.5 0.8 1.8 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 EOO00116.1 - 4.9e-07 29.7 0.1 1.1e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EOO00116.1 - 9.9e-07 29.1 0.0 2.4e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EOO00116.1 - 4.9e-05 23.1 0.1 0.0001 22.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EOO00116.1 - 0.00061 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EOO00116.1 - 0.00075 18.6 0.0 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 EOO00116.1 - 0.0029 17.9 0.1 0.0064 16.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EOO00116.1 - 0.014 15.1 0.1 0.031 13.9 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 EOO00116.1 - 0.027 14.4 0.1 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_14 PF13173.6 EOO00116.1 - 0.034 14.2 0.1 0.16 12.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EOO00116.1 - 0.079 13.5 0.2 3.1 8.3 0.1 2.8 1 1 1 2 2 2 0 ABC transporter PhoH PF02562.16 EOO00116.1 - 0.13 11.7 0.6 0.97 8.9 0.1 2.5 3 0 0 3 3 3 0 PhoH-like protein AAA PF00004.29 EOO00116.1 - 0.18 12.3 0.3 1.5 9.3 0.2 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EOO00116.1 - 0.18 12.2 1.6 0.84 10.0 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain DUF948 PF06103.11 EOO00117.1 - 0.005 17.1 0.4 1 9.7 0.2 2.3 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF948) DivIVA PF05103.13 EOO00117.1 - 0.013 15.6 0.2 0.018 15.1 0.2 1.3 1 0 0 1 1 1 0 DivIVA protein GOLGA2L5 PF15070.6 EOO00117.1 - 0.033 12.9 1.0 0.04 12.6 1.0 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DUF4523 PF15023.6 EOO00117.1 - 0.07 13.0 0.5 0.12 12.2 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4523) zf-RING_2 PF13639.6 EOO00118.1 - 5.8e-09 36.1 9.3 1e-08 35.4 9.3 1.4 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EOO00118.1 - 9.5e-06 25.7 11.3 1.5e-05 25.1 9.6 2.2 2 1 0 2 2 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 EOO00118.1 - 4.4e-05 23.4 2.2 0.0001 22.3 2.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EOO00118.1 - 0.00016 21.9 8.4 0.00039 20.7 8.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 EOO00118.1 - 0.0016 18.5 8.3 0.0034 17.5 8.3 1.6 1 0 0 1 1 1 1 RING-variant domain C1_1 PF00130.22 EOO00118.1 - 0.0018 18.1 3.7 0.0018 18.1 3.7 2.0 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.25 EOO00118.1 - 0.002 17.9 10.8 0.0037 17.1 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EOO00118.1 - 0.0029 17.2 5.6 0.0057 16.2 5.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EOO00118.1 - 0.016 15.1 6.2 0.031 14.1 6.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EOO00118.1 - 0.023 15.0 8.8 0.046 14.0 8.8 1.6 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.6 EOO00118.1 - 0.032 14.1 9.4 0.065 13.1 9.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_9 PF13901.6 EOO00118.1 - 0.2 11.6 7.0 0.37 10.7 7.0 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Prok-RING_4 PF14447.6 EOO00118.1 - 0.34 10.8 7.0 1.4 8.9 7.1 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Zf_RING PF16744.5 EOO00118.1 - 0.45 10.7 3.8 0.99 9.6 3.8 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 EOO00118.1 - 0.89 9.5 7.8 1.6 8.7 7.8 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 EOO00118.1 - 2.1 8.2 8.7 80 3.2 8.7 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 EOO00118.1 - 2.7 8.1 6.3 5.6 7.1 6.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Peptidase_S8 PF00082.22 EOO00119.1 - 3.1e-50 171.1 2.1 5.3e-50 170.4 2.1 1.4 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EOO00119.1 - 3.8e-06 27.6 0.0 7.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain RPT PF13446.6 EOO00119.1 - 0.15 12.0 0.6 0.39 10.7 0.6 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein FlgD_ig PF13860.6 EOO00119.1 - 0.16 11.8 1.9 1.4 8.8 0.0 2.9 4 0 0 4 4 4 0 FlgD Ig-like domain Laminin_II PF06009.12 EOO00120.1 - 3e-05 24.1 6.7 3.4e-05 23.9 1.4 2.1 2 0 0 2 2 2 1 Laminin Domain II Spc7 PF08317.11 EOO00120.1 - 0.00012 21.1 0.4 0.00016 20.6 0.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein ATG16 PF08614.11 EOO00120.1 - 0.0002 21.7 3.0 0.00029 21.1 2.9 1.4 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Tropomyosin PF00261.20 EOO00120.1 - 0.00023 20.6 1.8 0.00054 19.4 1.3 1.6 1 1 0 2 2 2 1 Tropomyosin Med9 PF07544.13 EOO00120.1 - 0.00039 20.5 0.7 0.0019 18.2 1.0 2.0 2 1 0 2 2 1 1 RNA polymerase II transcription mediator complex subunit 9 PspA_IM30 PF04012.12 EOO00120.1 - 0.0004 20.0 5.5 0.31 10.6 0.5 2.1 1 1 1 2 2 2 2 PspA/IM30 family FlxA PF14282.6 EOO00120.1 - 0.00043 20.2 1.1 0.0075 16.2 0.4 2.4 2 0 0 2 2 2 1 FlxA-like protein Prefoldin PF02996.17 EOO00120.1 - 0.00057 19.8 1.1 0.0093 15.9 0.6 2.3 2 0 0 2 2 2 1 Prefoldin subunit NPV_P10 PF05531.12 EOO00120.1 - 0.00068 20.0 7.6 0.01 16.3 3.2 2.5 1 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EOO00120.1 - 0.00099 19.2 9.0 0.13 12.2 0.4 2.3 1 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 EOO00120.1 - 0.001 19.3 1.4 0.0034 17.7 0.4 2.1 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5082 PF16888.5 EOO00120.1 - 0.0011 19.2 2.3 0.54 10.5 0.1 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) SKA1 PF07160.12 EOO00120.1 - 0.002 18.1 1.4 0.25 11.2 0.8 2.3 1 1 0 2 2 2 1 Spindle and kinetochore-associated protein 1 Filament PF00038.21 EOO00120.1 - 0.0036 17.0 2.0 0.078 12.5 1.9 2.1 1 1 1 2 2 2 1 Intermediate filament protein ADIP PF11559.8 EOO00120.1 - 0.0041 17.2 0.4 0.33 11.0 0.6 2.2 1 1 0 2 2 2 1 Afadin- and alpha -actinin-Binding Spc24 PF08286.11 EOO00120.1 - 0.0051 17.0 0.4 0.015 15.5 0.1 1.9 2 1 0 2 2 1 1 Spc24 subunit of Ndc80 DUF4618 PF15397.6 EOO00120.1 - 0.0072 15.8 1.2 0.06 12.8 0.7 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4618) FliJ PF02050.16 EOO00120.1 - 0.0074 16.5 0.0 0.58 10.4 0.0 2.2 2 0 0 2 2 2 1 Flagellar FliJ protein DUF3450 PF11932.8 EOO00120.1 - 0.0075 15.6 3.5 0.46 9.8 2.5 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) HIP1_clath_bdg PF16515.5 EOO00120.1 - 0.0081 16.7 0.6 0.019 15.6 0.6 1.6 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Prefoldin_2 PF01920.20 EOO00120.1 - 0.0082 16.1 0.9 0.31 11.0 0.4 2.3 2 0 0 2 2 2 1 Prefoldin subunit AAA_13 PF13166.6 EOO00120.1 - 0.0082 14.8 1.2 0.011 14.4 1.2 1.2 1 0 0 1 1 1 1 AAA domain Fib_alpha PF08702.10 EOO00120.1 - 0.0091 16.2 3.3 0.03 14.5 3.2 1.8 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 EOO00120.1 - 0.0098 13.9 0.3 0.02 12.8 0.1 1.5 1 1 1 2 2 2 1 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.9 EOO00120.1 - 0.011 15.8 0.6 0.025 14.6 0.3 1.7 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HrpB7 PF09486.10 EOO00120.1 - 0.011 16.1 7.7 4.3 7.7 0.5 3.1 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF4200 PF13863.6 EOO00120.1 - 0.011 16.1 0.5 0.18 12.2 0.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) SHE3 PF17078.5 EOO00120.1 - 0.012 15.4 0.3 0.022 14.5 0.3 1.5 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 TolA_bind_tri PF16331.5 EOO00120.1 - 0.014 15.5 0.3 0.044 13.9 0.3 1.7 2 0 0 2 2 1 0 TolA binding protein trimerisation MscS_porin PF12795.7 EOO00120.1 - 0.014 14.9 0.0 0.03 13.9 0.0 1.5 2 0 0 2 2 1 0 Mechanosensitive ion channel porin domain Ribosomal_S5_C PF03719.15 EOO00120.1 - 0.015 14.7 0.3 0.89 9.1 0.1 2.7 1 1 1 2 2 2 0 Ribosomal protein S5, C-terminal domain FlaC_arch PF05377.11 EOO00120.1 - 0.017 15.5 7.3 0.95 9.9 2.6 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 EOO00120.1 - 0.018 15.6 0.1 0.025 15.1 0.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region MAD PF05557.13 EOO00120.1 - 0.02 13.3 0.1 0.024 13.1 0.1 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein USP8_interact PF08941.10 EOO00120.1 - 0.026 14.3 0.7 0.14 11.9 0.1 2.0 2 0 0 2 2 2 0 USP8 interacting DUF1664 PF07889.12 EOO00120.1 - 0.027 14.5 7.0 0.16 12.0 2.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 EOO00120.1 - 0.028 14.9 3.4 0.048 14.1 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 TMF_DNA_bd PF12329.8 EOO00120.1 - 0.029 14.4 1.3 0.1 12.6 1.2 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Rab5-bind PF09311.11 EOO00120.1 - 0.029 13.8 2.8 0.05 13.0 2.0 1.6 1 1 0 1 1 1 0 Rabaptin-like protein Tropomyosin_1 PF12718.7 EOO00120.1 - 0.031 14.4 3.1 0.056 13.6 2.0 1.7 2 1 0 2 2 1 0 Tropomyosin like Syntaxin-6_N PF09177.11 EOO00120.1 - 0.031 14.8 0.7 0.28 11.8 0.3 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Filo_VP35 PF02097.15 EOO00120.1 - 0.031 13.3 5.3 0.059 12.4 0.1 2.1 2 0 0 2 2 2 0 Filoviridae VP35 DUF948 PF06103.11 EOO00120.1 - 0.032 14.5 12.6 11 6.3 6.6 3.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 EOO00120.1 - 0.032 14.3 1.2 0.059 13.4 0.4 1.8 2 0 0 2 2 1 0 Designed helical repeat protein 10 domain XhlA PF10779.9 EOO00120.1 - 0.035 14.3 0.9 0.68 10.2 0.2 2.8 2 1 1 3 3 3 0 Haemolysin XhlA DMPK_coil PF08826.10 EOO00120.1 - 0.038 14.1 1.2 0.089 12.9 1.2 1.5 1 0 0 1 1 1 0 DMPK coiled coil domain like DivIC PF04977.15 EOO00120.1 - 0.04 13.7 1.5 0.22 11.3 1.3 2.2 2 1 1 3 3 2 0 Septum formation initiator DUF4407 PF14362.6 EOO00120.1 - 0.041 13.2 5.9 0.18 11.1 5.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RapA_C PF12137.8 EOO00120.1 - 0.043 12.9 2.8 0.082 11.9 2.6 1.4 1 1 0 1 1 1 0 RNA polymerase recycling family C-terminal GAS PF13851.6 EOO00120.1 - 0.043 13.2 0.1 0.083 12.2 0.1 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4795 PF16043.5 EOO00120.1 - 0.046 13.3 3.4 0.28 10.8 1.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) SlyX PF04102.12 EOO00120.1 - 0.064 13.9 3.8 0.14 12.8 2.4 2.2 1 1 1 2 2 2 0 SlyX Phage_GP20 PF06810.11 EOO00120.1 - 0.069 12.9 7.1 0.3 10.9 2.1 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 Fez1 PF06818.15 EOO00120.1 - 0.079 13.4 1.0 0.47 10.9 0.6 1.9 1 1 1 2 2 2 0 Fez1 Dynamitin PF04912.14 EOO00120.1 - 0.092 12.1 4.8 0.13 11.6 1.1 2.0 1 1 0 2 2 2 0 Dynamitin DUF2730 PF10805.8 EOO00120.1 - 0.11 12.6 1.9 0.4 10.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) COG5 PF10392.9 EOO00120.1 - 0.11 12.7 0.4 0.48 10.6 0.1 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Seryl_tRNA_N PF02403.22 EOO00120.1 - 0.11 12.7 2.3 0.38 11.0 0.6 2.3 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain COG6 PF06419.11 EOO00120.1 - 0.12 10.6 1.6 0.24 9.6 0.3 1.8 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 DUF812 PF05667.11 EOO00120.1 - 0.14 11.0 2.5 0.29 10.0 1.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF812) GCP_N_terminal PF17681.1 EOO00120.1 - 0.14 11.7 0.0 15 5.1 0.0 2.1 1 1 1 2 2 2 0 Gamma tubulin complex component N-terminal DUF4988 PF16378.5 EOO00120.1 - 0.14 11.8 6.4 0.94 9.1 0.4 2.7 1 1 2 3 3 3 0 Domain of unknown function Cob_adeno_trans PF01923.18 EOO00120.1 - 0.15 12.2 1.9 0.42 10.7 0.5 2.0 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DASH_Dam1 PF08653.10 EOO00120.1 - 0.15 11.9 0.3 2.4 8.0 0.0 2.6 3 0 0 3 3 2 0 DASH complex subunit Dam1 Urease_gamma PF00547.18 EOO00120.1 - 0.15 12.4 3.4 0.15 12.4 0.5 2.2 2 0 0 2 2 2 0 Urease, gamma subunit CLZ PF16526.5 EOO00120.1 - 0.15 12.4 2.1 0.38 11.1 2.1 1.6 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BST2 PF16716.5 EOO00120.1 - 0.16 12.6 1.2 1 10.0 1.4 2.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 YabA PF06156.13 EOO00120.1 - 0.17 12.5 1.0 1.7 9.3 0.4 2.4 2 1 0 2 2 2 0 Initiation control protein YabA COG2 PF06148.11 EOO00120.1 - 0.2 11.7 4.2 1.2 9.2 1.5 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ABC_tran_CTD PF16326.5 EOO00120.1 - 0.23 11.7 2.2 3.4 8.0 2.1 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain DUF2203 PF09969.9 EOO00120.1 - 0.29 11.9 1.6 1.8 9.3 1.6 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF3829 PF12889.7 EOO00120.1 - 0.3 10.5 2.9 2.4 7.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) DUF4094 PF13334.6 EOO00120.1 - 0.41 11.1 2.7 4.2 7.8 0.7 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) EzrA PF06160.12 EOO00120.1 - 0.42 8.7 4.3 0.8 7.8 1.4 2.0 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA WXG100 PF06013.12 EOO00120.1 - 0.57 10.4 4.3 14 6.0 0.7 3.5 2 2 0 2 2 2 0 Proteins of 100 residues with WXG ISG65-75 PF11727.8 EOO00120.1 - 0.72 9.0 5.5 0.42 9.8 1.2 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein MIP-T3_C PF17749.1 EOO00120.1 - 0.91 9.5 5.1 16 5.5 0.1 3.0 2 1 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region DUF4140 PF13600.6 EOO00120.1 - 1.2 9.6 7.0 2.8 8.4 4.2 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Zein-binding PF04576.15 EOO00120.1 - 2 8.8 5.2 0.93 9.8 0.1 2.8 2 1 0 3 3 2 0 Zein-binding Abhydrolase_1 PF00561.20 EOO00121.1 - 4.9e-17 62.4 0.0 3.5e-15 56.3 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EOO00121.1 - 3e-13 49.8 0.0 5.8e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Pmp3 PF01679.17 EOO00122.1 - 1e-19 70.4 10.5 1.8e-19 69.7 10.5 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator MFS_1 PF07690.16 EOO00123.1 - 2.9e-13 49.5 48.2 8.9e-07 28.1 27.8 2.7 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2107 PF09880.9 EOO00123.1 - 0.0049 17.0 1.6 0.014 15.5 0.2 2.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2107) Pox_M2 PF04887.12 EOO00123.1 - 0.14 11.6 0.2 0.54 9.7 0.0 2.0 2 0 0 2 2 2 0 Poxvirus M2 protein IPK PF03770.16 EOO00124.1 - 2.1e-53 181.2 0.0 2.6e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Metal_resist PF13801.6 EOO00124.1 - 0.014 15.6 0.4 0.035 14.3 0.4 1.6 1 0 0 1 1 1 0 Heavy-metal resistance CdiI PF07262.11 EOO00124.1 - 0.017 14.9 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 CDI immunity protein Peptidase_S66 PF02016.15 EOO00125.1 - 9.2e-26 90.3 0.0 1.4e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 EOO00125.1 - 1.4e-24 87.0 0.0 2.1e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain p450 PF00067.22 EOO00126.1 - 4.2e-39 134.6 0.0 6.7e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S8 PF00082.22 EOO00127.1 - 4.5e-33 114.8 1.9 7e-33 114.2 1.9 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EOO00127.1 - 3.4e-13 50.3 0.1 7.8e-13 49.1 0.1 1.7 1 0 0 1 1 1 1 Fn3-like domain Big_8 PF17961.1 EOO00127.1 - 1.5e-06 28.3 0.1 5.8e-06 26.4 0.1 2.0 1 0 0 1 1 1 1 Bacterial Ig domain DUF3378 PF11858.8 EOO00127.1 - 0.062 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) DUF2057 PF09829.9 EOO00127.1 - 0.14 12.3 0.1 12 5.9 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF916 PF06030.12 EOO00127.1 - 0.16 12.1 0.0 1.1 9.4 0.0 2.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF916) NmrA PF05368.13 EOO00128.1 - 1.6e-33 116.2 0.0 2.3e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO00128.1 - 7.6e-10 39.0 0.1 1.1e-09 38.5 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EOO00128.1 - 6.1e-06 25.9 0.0 8.9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EOO00128.1 - 0.002 18.4 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 EOO00128.1 - 0.034 13.5 0.0 0.092 12.1 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EOO00128.1 - 0.074 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DAO PF01266.24 EOO00129.1 - 1.6e-18 67.4 0.0 2.1e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EOO00129.1 - 0.17 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain TauD PF02668.16 EOO00130.1 - 2.6e-12 47.1 0.0 3.1e-07 30.5 0.0 2.2 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family Methyltransf_11 PF08241.12 EOO00131.1 - 1.7e-05 25.4 0.0 3.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO00131.1 - 0.0045 17.7 0.0 0.0096 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO00131.1 - 0.023 15.4 0.0 0.048 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EOO00131.1 - 0.048 13.5 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.22 EOO00132.1 - 9e-55 186.2 0.0 1.1e-54 186.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SGL PF08450.12 EOO00133.1 - 3.3e-12 46.5 0.1 1.4e-11 44.5 0.1 2.0 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 EOO00133.1 - 0.011 15.8 0.6 0.082 13.0 0.2 2.7 2 0 0 2 2 2 0 NHL repeat SBBP PF06739.11 EOO00133.1 - 0.018 15.0 0.1 0.065 13.2 0.1 2.0 1 0 0 1 1 1 0 Beta-propeller repeat Coprogen_oxidas PF01218.18 EOO00133.1 - 0.16 10.6 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase PQQ_3 PF13570.6 EOO00133.1 - 2.6 8.7 5.2 8.4 7.0 0.2 4.0 4 1 0 4 4 4 0 PQQ-like domain Bac_rhodopsin PF01036.18 EOO00134.1 - 2.9e-31 108.8 21.3 4e-31 108.3 21.3 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein GMC_oxred_N PF00732.19 EOO00135.1 - 2.5e-60 204.4 0.1 3.1e-60 204.1 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EOO00135.1 - 1.1e-28 100.6 0.0 2.5e-28 99.4 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EOO00135.1 - 3.5e-06 26.3 0.2 1.2e-05 24.5 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EOO00135.1 - 6.1e-05 22.3 0.1 0.0017 17.5 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EOO00135.1 - 7.9e-05 22.8 0.1 0.00022 21.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EOO00135.1 - 0.00015 21.1 0.2 0.00048 19.4 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 EOO00135.1 - 0.00028 20.2 0.0 0.011 15.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EOO00135.1 - 0.001 18.7 2.2 0.017 14.7 2.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EOO00135.1 - 0.0015 17.4 0.1 0.0022 16.8 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EOO00135.1 - 0.0036 16.6 0.8 0.19 11.0 0.5 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AA_synth PF06684.11 EOO00135.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Amino acid synthesis adh_short PF00106.25 EOO00137.1 - 5e-20 71.8 0.4 6.4e-20 71.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO00137.1 - 4.4e-15 55.9 0.1 2.2e-14 53.6 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO00137.1 - 3e-08 33.8 0.0 3.8e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EOO00137.1 - 0.018 14.2 0.3 0.025 13.7 0.3 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 EOO00137.1 - 0.018 14.9 2.2 0.038 13.9 2.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EOO00137.1 - 0.033 13.6 0.3 0.16 11.4 0.3 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EOO00137.1 - 0.085 12.9 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Arb1 PF09692.10 EOO00138.1 - 2.4e-141 471.5 0.2 3e-141 471.2 0.2 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Methyltransf_23 PF13489.6 EOO00140.1 - 0.0027 17.6 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO00140.1 - 0.0076 16.9 0.0 0.014 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO00140.1 - 0.015 15.9 0.0 0.024 15.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EOO00140.1 - 0.02 15.6 0.0 0.031 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TRI12 PF06609.13 EOO00141.1 - 9.7e-48 163.0 20.1 6.7e-24 84.2 6.6 2.1 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EOO00141.1 - 2.9e-28 98.8 35.1 2.9e-28 98.8 35.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO00141.1 - 1e-09 37.8 5.1 1e-09 37.8 5.1 2.5 1 1 0 2 2 2 1 Sugar (and other) transporter AtuA PF07287.11 EOO00142.1 - 1.5e-127 425.2 0.6 1.8e-127 424.9 0.6 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA YqgF PF14639.6 EOO00142.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 RANK_CRD_2 PF18278.1 EOO00143.1 - 0.067 13.4 0.3 0.15 12.2 0.3 1.5 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Alpha_L_fucos PF01120.17 EOO00144.1 - 8.4e-87 291.9 6.7 1.1e-86 291.4 6.7 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.6 EOO00144.1 - 0.015 15.4 0.1 0.037 14.2 0.0 1.7 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 CARDB PF07705.11 EOO00144.1 - 0.029 14.6 0.2 0.09 13.0 0.2 1.8 1 0 0 1 1 1 0 CARDB Sugar_tr PF00083.24 EOO00145.1 - 8.1e-05 21.7 0.9 9.4e-05 21.5 0.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter NAD_binding_10 PF13460.6 EOO00146.1 - 5.5e-12 45.9 0.0 6.4e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EOO00146.1 - 3.9e-07 29.9 0.1 5.7e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family GFO_IDH_MocA PF01408.22 EOO00146.1 - 0.054 14.3 0.1 0.089 13.6 0.1 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 EOO00146.1 - 0.096 13.0 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain WD40 PF00400.32 EOO00147.1 - 6.7e-27 93.2 3.0 1.8e-05 25.4 0.0 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO00147.1 - 8.8e-06 25.9 0.3 0.32 11.3 0.1 4.4 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EOO00147.1 - 0.0015 17.6 1.3 1.1 8.2 0.2 3.3 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Zn_Tnp_IS1595 PF12760.7 EOO00147.1 - 0.0063 16.5 3.0 0.013 15.4 3.0 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Nup160 PF11715.8 EOO00147.1 - 0.024 13.3 3.2 3.9 6.0 0.4 3.2 3 1 1 4 4 4 0 Nucleoporin Nup120/160 DUF4875 PF16175.5 EOO00147.1 - 0.027 14.6 0.6 1.9 8.7 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4875) Cytochrom_D1 PF02239.16 EOO00147.1 - 0.043 12.3 0.1 6.9 5.1 0.0 2.6 2 1 0 3 3 3 0 Cytochrome D1 heme domain TF_Zn_Ribbon PF08271.12 EOO00147.1 - 0.062 12.8 0.5 0.15 11.6 0.5 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding PD40 PF07676.12 EOO00147.1 - 0.075 13.0 2.0 5.4 7.1 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nudix_N_2 PF14803.6 EOO00147.1 - 0.28 11.2 3.5 0.95 9.4 3.5 1.9 1 0 0 1 1 1 0 Nudix N-terminal Zn_ribbon_SprT PF17283.2 EOO00147.1 - 1.3 9.0 3.6 2.6 8.0 3.6 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Sugar_tr PF00083.24 EOO00148.1 - 3.8e-60 204.0 17.2 1.4e-52 179.1 7.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO00148.1 - 5.2e-24 84.8 40.2 1e-14 54.2 20.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily IRK PF01007.20 EOO00148.1 - 0.56 10.0 6.3 2.5 7.9 0.7 2.5 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Helicase_C PF00271.31 EOO00149.1 - 4.6e-13 49.5 0.0 7.9e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EOO00149.1 - 0.0046 16.2 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF4611 PF15387.6 EOO00149.1 - 0.047 13.9 7.1 0.083 13.1 7.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) VID27_N PF17748.1 EOO00149.1 - 0.13 12.1 5.8 0.061 13.2 3.7 1.5 2 0 0 2 2 2 0 VID27 N-terminal region NOA36 PF06524.12 EOO00149.1 - 0.49 9.7 11.1 0.65 9.3 11.1 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 EOO00149.1 - 2.7 8.0 6.5 4.1 7.4 6.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal CAF1C_H4-bd PF12265.8 EOO00151.1 - 2.5e-14 53.3 0.1 1.3e-13 51.0 0.0 2.3 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EOO00151.1 - 6e-14 52.2 8.1 8.9e-07 29.5 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO00151.1 - 1.6e-08 34.7 0.6 0.0004 20.6 0.1 2.8 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EOO00151.1 - 0.047 12.6 2.8 0.045 12.7 0.7 1.9 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Glyco_hydro_26 PF02156.15 EOO00154.1 - 3.3e-08 33.3 2.3 3.3e-08 33.3 2.3 1.7 1 1 1 2 2 2 1 Glycosyl hydrolase family 26 Cellulase PF00150.18 EOO00154.1 - 0.00021 20.8 1.3 0.00021 20.8 1.3 1.8 1 1 1 2 2 2 1 Cellulase (glycosyl hydrolase family 5) UDPG_MGDP_dh PF00984.19 EOO00155.1 - 1.5e-28 98.8 0.0 4e-28 97.4 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EOO00155.1 - 3.9e-24 85.1 0.1 1.6e-18 67.1 0.0 2.5 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh_N PF03721.14 EOO00155.1 - 1.3e-22 80.3 0.0 5.3e-22 78.3 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glycos_transf_2 PF00535.26 EOO00156.1 - 7.8e-24 84.4 0.1 1.1e-23 84.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EOO00156.1 - 2.7e-11 43.3 0.0 4.4e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 EOO00156.1 - 9.1e-11 42.0 2.6 1.4e-10 41.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EOO00156.1 - 1.4e-08 34.9 0.0 1.9e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 AhpC-TSA PF00578.21 EOO00157.1 - 3.6e-38 130.3 0.0 4.9e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EOO00157.1 - 1.3e-13 50.9 0.0 1.9e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EOO00157.1 - 2e-11 43.5 0.0 3.8e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Sugar_tr PF00083.24 EOO00158.1 - 5e-118 394.8 23.4 4.7e-73 246.6 3.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO00158.1 - 7.6e-17 61.3 30.2 7.6e-17 61.3 30.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Thioredoxin PF00085.20 EOO00159.1 - 4.9e-22 77.9 0.0 7.7e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EOO00159.1 - 2.8e-06 27.7 0.1 7.2e-05 23.2 0.2 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EOO00159.1 - 0.0001 21.8 0.0 0.00026 20.4 0.0 1.5 1 1 1 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EOO00159.1 - 0.00088 19.6 0.0 0.002 18.4 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EOO00159.1 - 0.016 14.9 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.21 EOO00159.1 - 0.058 13.3 0.1 0.13 12.2 0.1 1.5 1 1 0 1 1 1 0 AhpC/TSA family HyaE PF07449.11 EOO00159.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE fn3_5 PF06280.12 EOO00161.1 - 4.2e-18 66.1 1.0 8.2e-18 65.2 0.1 2.0 3 0 0 3 3 3 1 Fn3-like domain Peptidase_S8 PF00082.22 EOO00161.1 - 5.2e-05 22.7 0.6 0.00012 21.5 0.1 1.7 2 0 0 2 2 2 1 Subtilase family DAO PF01266.24 EOO00162.1 - 2.7e-37 129.2 1.2 3.1e-37 129.0 1.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EOO00162.1 - 0.026 13.8 1.1 0.31 10.2 1.1 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EOO00162.1 - 0.075 13.3 0.3 0.2 11.9 0.3 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EOO00162.1 - 0.099 11.9 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HpcH_HpaI PF03328.14 EOO00163.1 - 7.5e-14 51.4 0.3 9.2e-14 51.1 0.3 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 EOO00163.1 - 0.02 13.8 0.1 0.027 13.4 0.1 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain UDPG_MGDP_dh_N PF03721.14 EOO00164.1 - 1.4e-47 161.7 0.0 7.7e-30 103.9 0.1 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EOO00164.1 - 1.7e-32 111.5 0.0 3.7e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EOO00164.1 - 3.8e-22 78.7 0.0 3.1e-18 66.1 0.0 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 EOO00164.1 - 0.022 15.0 0.1 0.084 13.1 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 EOO00164.1 - 0.049 13.8 0.0 4.6 7.4 0.1 2.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Rootletin PF15035.6 EOO00165.1 - 0.17 11.9 7.0 0.25 11.3 7.0 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TMF_TATA_bd PF12325.8 EOO00165.1 - 0.44 10.8 7.2 1.1 9.5 7.2 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 EOO00165.1 - 0.67 10.0 14.2 1.6 8.8 14.2 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 EOO00165.1 - 1.1 8.0 7.3 1.5 7.6 7.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 EOO00165.1 - 1.5 8.1 7.0 2.4 7.4 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GYF PF02213.16 EOO00166.1 - 1.4e-17 63.1 0.3 2.7e-17 62.1 0.3 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EOO00166.1 - 0.039 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 GYF domain 2 Glyco_hydro_cc PF11790.8 EOO00167.1 - 1.2e-69 234.5 1.9 1.4e-69 234.3 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_76 PF03663.14 EOO00168.1 - 5.1e-56 190.8 3.9 5.6e-56 190.6 3.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EOO00168.1 - 2.7e-05 23.4 1.8 0.015 14.4 0.0 3.3 2 2 0 3 3 3 2 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 EOO00168.1 - 0.0051 15.4 0.4 0.56 8.6 0.3 2.2 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 C5-epim_C PF06662.13 EOO00168.1 - 0.035 13.6 0.0 0.4 10.2 0.0 2.6 3 0 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus Rsbr_N PF08678.10 EOO00168.1 - 0.044 13.8 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 Rsbr N terminal Cutinase PF01083.22 EOO00170.1 - 4.2e-46 157.2 0.3 5.7e-46 156.7 0.3 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EOO00170.1 - 0.035 13.7 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Methyltransf_25 PF13649.6 EOO00171.1 - 3.2e-09 37.4 0.0 1.1e-08 35.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EOO00171.1 - 2e-06 27.7 0.0 3.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EOO00171.1 - 9.4e-06 26.3 0.0 3.4e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EOO00171.1 - 4e-05 23.5 0.0 6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EOO00171.1 - 0.00017 21.0 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 EOO00171.1 - 0.0002 21.2 0.0 0.00028 20.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EOO00171.1 - 0.00028 21.9 0.0 0.00065 20.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO00171.1 - 0.00055 20.5 0.0 0.0013 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 EOO00171.1 - 0.001 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.18 EOO00171.1 - 0.004 16.5 0.0 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EOO00171.1 - 0.005 16.4 0.0 0.0092 15.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.9 EOO00171.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase FtsJ PF01728.19 EOO00171.1 - 0.054 13.6 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase NodS PF05401.11 EOO00171.1 - 0.06 13.0 0.0 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 Nodulation protein S (NodS) Fibrillarin PF01269.17 EOO00171.1 - 0.076 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin RrnaAD PF00398.20 EOO00171.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Sulfate_transp PF00916.20 EOO00173.1 - 4.6e-76 256.0 12.2 6.1e-76 255.6 12.2 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EOO00173.1 - 7.9e-17 61.0 0.0 1.6e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EOO00173.1 - 0.021 15.2 0.0 0.069 13.5 0.0 2.0 1 0 0 1 1 1 0 STAS domain MFS_MOT1 PF16983.5 EOO00173.1 - 1.1 9.7 10.4 0.031 14.7 1.8 2.5 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily CTP_transf_1 PF01148.20 EOO00174.1 - 4.2e-79 266.1 23.8 5.2e-79 265.7 23.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family YqzM PF14141.6 EOO00174.1 - 0.053 13.6 0.3 0.053 13.6 0.3 3.6 3 0 0 3 3 3 0 YqzM-like protein Thiolase_N PF00108.23 EOO00175.1 - 1.7e-67 227.6 0.1 2.1e-67 227.2 0.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EOO00175.1 - 2.6e-39 133.7 0.2 6.3e-39 132.4 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EOO00175.1 - 0.18 11.4 2.5 0.45 10.0 1.5 2.0 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain NAD_binding_10 PF13460.6 EOO00176.1 - 0.00018 21.5 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EOO00176.1 - 0.001 19.3 0.1 0.0014 18.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EOO00176.1 - 0.0019 17.7 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EOO00176.1 - 0.012 14.8 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein DapB_N PF01113.20 EOO00176.1 - 0.042 14.0 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 EOO00176.1 - 0.084 11.9 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EOO00176.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 KR domain NmrA PF05368.13 EOO00176.1 - 0.15 11.6 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.15 EOO00176.1 - 0.17 10.9 0.1 0.32 10.1 0.1 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein GTP_cyclohydroI PF01227.22 EOO00177.1 - 1.4e-73 246.1 0.2 1.9e-73 245.7 0.2 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EOO00177.1 - 0.0015 18.7 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein Cu_amine_oxidN2 PF02727.16 EOO00177.1 - 0.089 13.0 0.0 3.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Copper amine oxidase, N2 domain MFS_1 PF07690.16 EOO00178.1 - 3.5e-38 131.4 32.4 3.6e-38 131.4 31.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily GST_C_2 PF13410.6 EOO00180.1 - 0.00029 20.8 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EOO00180.1 - 0.048 13.5 0.0 0.062 13.1 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EOO00180.1 - 0.18 12.0 0.0 0.19 11.9 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_M20 PF01546.28 EOO00182.1 - 3e-19 69.5 0.0 4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EOO00182.1 - 8.2e-06 25.7 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EOO00182.1 - 0.0054 16.5 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 AAA PF00004.29 EOO00183.1 - 5.4e-15 56.0 0.0 1e-14 55.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EOO00183.1 - 3.9e-05 23.9 0.7 0.0031 17.8 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EOO00183.1 - 7.2e-05 23.2 1.9 0.001 19.5 1.9 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EOO00183.1 - 0.022 14.8 0.0 0.05 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EOO00183.1 - 0.073 13.2 0.0 0.79 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Pfk_N PF18468.1 EOO00183.1 - 0.13 12.7 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphofructokinase N-terminal domain yeast NINJA_B PF16136.5 EOO00183.1 - 0.96 9.8 5.9 0.88 10.0 1.5 2.3 2 0 0 2 2 2 0 Putative nuclear localisation signal UvdE PF03851.14 EOO00184.1 - 4.4e-100 334.5 0.0 5.3e-100 334.2 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE adh_short PF00106.25 EOO00185.1 - 2.9e-29 101.9 0.0 7.2e-29 100.6 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO00185.1 - 2e-16 60.2 0.0 3.7e-16 59.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO00185.1 - 6.6e-08 32.7 0.0 8.9e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO00185.1 - 2.4e-06 27.2 0.0 2.9e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO00185.1 - 2.4e-05 23.9 0.0 3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase tRNA-synt_1c PF00749.21 EOO00186.1 - 2.4e-100 335.4 0.1 3.9e-100 334.8 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EOO00186.1 - 3e-39 134.7 0.1 4.8e-39 134.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 EOO00186.1 - 0.0027 17.1 0.2 0.0071 15.7 0.2 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Sterol_MT_C PF08498.10 EOO00187.1 - 3.7e-29 100.8 0.8 6.1e-29 100.1 0.8 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EOO00187.1 - 2.8e-22 79.2 0.0 4.2e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO00187.1 - 3.1e-21 75.9 0.0 6.5e-21 74.8 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO00187.1 - 4.4e-18 65.5 0.0 5.5e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO00187.1 - 1.5e-12 48.1 0.0 5.4e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EOO00187.1 - 5.2e-12 45.9 0.1 9.2e-12 45.1 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EOO00187.1 - 6e-12 45.4 0.0 1.2e-11 44.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EOO00187.1 - 6.3e-09 35.5 0.0 8.4e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 EOO00187.1 - 0.00033 20.0 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_15 PF09445.10 EOO00187.1 - 0.00034 20.2 0.0 0.0005 19.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 EOO00187.1 - 0.00062 19.2 0.0 0.00084 18.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 EOO00187.1 - 0.002 18.0 0.0 0.0034 17.3 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 EOO00187.1 - 0.017 14.7 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 EOO00187.1 - 0.033 14.2 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EOO00187.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 EOO00187.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DRE2_N PF16803.5 EOO00187.1 - 0.2 11.9 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus SGL PF08450.12 EOO00188.1 - 1.1e-11 44.8 0.1 2.4e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF5074 PF16819.5 EOO00188.1 - 0.087 12.9 0.3 0.93 9.6 0.0 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF5074) MFS_1 PF07690.16 EOO00189.1 - 8.7e-23 80.8 33.5 8.7e-23 80.8 33.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EOO00189.1 - 0.0099 14.2 0.4 0.0099 14.2 0.4 2.5 2 2 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF5345 PF17280.2 EOO00189.1 - 0.014 15.3 2.4 0.036 14.0 2.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Trp_oprn_chp PF09534.10 EOO00189.1 - 3.4 7.4 6.9 0.63 9.8 2.7 2.0 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PdxA PF04166.12 EOO00190.1 - 7.6e-22 78.0 0.0 1e-21 77.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA HHH_5 PF14520.6 EOO00190.1 - 0.04 14.5 0.2 0.19 12.4 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain AMP-binding PF00501.28 EOO00191.1 - 9.6e-13 47.5 0.6 4.9e-08 32.0 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EOO00191.1 - 1.8e-05 25.6 0.0 4.8e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GST_N PF02798.20 EOO00192.1 - 1.2e-11 44.7 0.0 1.3e-11 44.7 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EOO00192.1 - 3.9e-08 33.6 0.0 4.4e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EOO00192.1 - 7e-07 29.5 0.0 8.4e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Aminotran_1_2 PF00155.21 EOO00193.1 - 3.2e-68 230.5 0.0 3.7e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_S9 PF00326.21 EOO00194.1 - 1e-32 113.4 0.0 1.6e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 EOO00194.1 - 8.8e-20 70.1 6.0 5.8e-07 29.3 0.3 5.7 5 0 0 5 5 5 4 WD40-like Beta Propeller Repeat Abhydrolase_6 PF12697.7 EOO00194.1 - 1.7e-07 32.1 1.8 1.2e-06 29.4 1.8 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EOO00194.1 - 7.5e-06 25.6 0.0 0.00015 21.4 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family DPPIV_N PF00930.21 EOO00194.1 - 1.2e-05 24.2 0.0 0.055 12.2 0.0 3.3 2 2 1 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Hydrolase_4 PF12146.8 EOO00194.1 - 2.4e-05 23.7 0.0 0.009 15.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EOO00194.1 - 0.00012 21.9 0.0 0.41 10.4 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EOO00194.1 - 0.00044 20.0 0.3 0.0059 16.3 0.3 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold ANAPC4_WD40 PF12894.7 EOO00194.1 - 0.00082 19.6 0.0 0.99 9.7 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Abhydrolase_4 PF08386.10 EOO00194.1 - 0.0036 17.4 0.0 0.0081 16.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_3 PF07859.13 EOO00194.1 - 0.02 14.8 0.0 0.047 13.5 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Gmad1 PF10647.9 EOO00194.1 - 0.028 14.2 0.0 6.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain WD40 PF00400.32 EOO00194.1 - 0.1 13.5 0.1 31 5.7 0.0 4.6 4 0 0 4 4 4 0 WD domain, G-beta repeat LIP PF03583.14 EOO00194.1 - 0.1 11.9 0.3 0.59 9.4 0.4 1.9 2 0 0 2 2 2 0 Secretory lipase DUF1828 PF08861.10 EOO00194.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF1828 Peptidase_S9_N PF02897.15 EOO00194.1 - 0.17 10.7 0.0 12 4.6 0.0 2.4 3 0 0 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Sulfate_transp PF00916.20 EOO00195.1 - 2.1e-20 72.9 0.0 2.8e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EOO00195.1 - 1.8e-10 40.5 0.0 3.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain IPP-2 PF04979.14 EOO00196.1 - 6.5e-25 88.4 2.0 6.5e-25 88.4 2.0 2.0 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) MRC1 PF09444.10 EOO00196.1 - 0.02 15.4 0.9 0.064 13.8 0.9 1.9 1 0 0 1 1 1 0 MRC1-like domain adh_short PF00106.25 EOO00197.1 - 1.8e-14 53.7 0.0 1.5e-12 47.4 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EOO00197.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 KR domain Opi1 PF08618.10 EOO00198.1 - 1.8e-39 136.2 0.2 7.4e-28 97.9 0.0 2.3 1 1 1 2 2 2 2 Transcription factor Opi1 DUF4065 PF13274.6 EOO00198.1 - 0.07 14.0 0.0 0.14 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) Pyr_redox_2 PF07992.14 EOO00199.1 - 1.2e-52 178.9 0.9 1.6e-52 178.5 0.9 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EOO00199.1 - 7.2e-24 84.2 0.0 1.2e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EOO00199.1 - 6.4e-21 74.7 0.5 2.1e-20 73.1 0.5 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EOO00199.1 - 4.4e-08 32.7 0.4 5.5e-07 29.1 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EOO00199.1 - 4.8e-06 26.7 0.1 0.055 13.7 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EOO00199.1 - 4e-05 23.4 0.5 1.2 8.6 0.1 3.3 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EOO00199.1 - 5.2e-05 22.1 0.7 0.47 9.1 0.1 3.3 3 1 1 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 EOO00199.1 - 0.00035 20.0 0.1 0.00063 19.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EOO00199.1 - 0.0008 19.7 0.4 0.057 13.7 0.2 2.4 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 EOO00199.1 - 0.0029 18.0 0.0 0.0058 17.1 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 EOO00199.1 - 0.0043 16.2 0.6 2.1 7.3 0.0 3.4 4 0 0 4 4 4 1 FAD binding domain K_oxygenase PF13434.6 EOO00199.1 - 0.0083 15.3 0.0 0.26 10.4 0.0 2.5 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 EOO00199.1 - 0.016 15.1 0.1 0.039 13.9 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EOO00199.1 - 0.069 12.2 0.3 5.7 5.9 0.2 2.5 2 1 0 2 2 2 0 Glucose inhibited division protein A XdhC_C PF13478.6 EOO00199.1 - 0.081 13.4 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain LpxI_N PF17930.1 EOO00199.1 - 0.13 12.1 0.2 2.3 8.1 0.2 2.5 1 1 0 1 1 1 0 LpxI N-terminal domain DIOX_N PF14226.6 EOO00200.1 - 2.5e-13 50.8 0.0 1.2e-11 45.3 0.0 2.5 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EOO00200.1 - 4.2e-09 36.8 0.0 8.2e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 EOO00201.1 - 2.2e-40 138.7 46.7 2.2e-40 138.7 46.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EOO00201.1 - 3.1e-15 55.6 12.5 4.6e-15 55.1 12.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SET PF00856.28 EOO00202.1 - 2.5e-21 76.8 0.0 5.2e-21 75.8 0.0 1.5 2 0 0 2 2 2 1 SET domain FAD_binding_3 PF01494.19 EOO00203.1 - 1.5e-77 261.3 0.0 2e-77 260.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EOO00203.1 - 1.6e-17 64.1 0.0 2.7e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EOO00203.1 - 4.7e-07 29.3 0.0 0.00022 20.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EOO00203.1 - 5.3e-05 23.0 0.0 0.0002 21.0 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EOO00203.1 - 0.00047 20.7 0.0 0.11 13.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EOO00203.1 - 0.00052 19.2 0.1 0.003 16.7 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EOO00203.1 - 0.00063 18.5 0.0 0.0013 17.5 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EOO00203.1 - 0.00094 18.5 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EOO00203.1 - 0.0011 18.1 0.1 0.002 17.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EOO00203.1 - 0.0017 18.6 0.0 0.0055 16.9 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EOO00203.1 - 0.0032 16.8 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EOO00203.1 - 0.01 15.2 0.1 0.017 14.5 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EOO00203.1 - 0.06 12.4 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ThiF PF00899.21 EOO00203.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 EOO00203.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EOO00203.1 - 0.11 11.9 0.0 0.46 9.8 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EOO00203.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Polysacc_deac_1 PF01522.21 EOO00204.1 - 1.5e-15 57.2 0.0 2.8e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EOO00204.1 - 4.2e-05 23.3 0.1 0.00015 21.5 0.0 2.0 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) Transketolase_N PF00456.21 EOO00205.1 - 2.2e-127 424.6 0.0 3.3e-127 424.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain FAA_hydrolase PF01557.18 EOO00205.1 - 2.7e-58 197.2 0.0 4.3e-58 196.5 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Transket_pyr PF02779.24 EOO00205.1 - 8.9e-22 77.6 0.0 2.6e-20 72.8 0.0 2.3 1 1 1 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EOO00205.1 - 2e-09 37.4 0.0 4.6e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EOO00205.1 - 9.2e-07 28.3 0.0 3.1e-06 26.6 0.0 1.7 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EOO00205.1 - 0.00022 20.3 0.0 0.0004 19.4 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component PepSY_2 PF13670.6 EOO00205.1 - 0.015 15.3 0.1 0.04 13.9 0.1 1.7 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain ApoB100_C PF12491.8 EOO00205.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal p450 PF00067.22 EOO00206.1 - 4.4e-45 154.3 0.0 3.3e-44 151.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 SBP_bac_3 PF00497.20 EOO00207.1 - 0.00023 20.7 0.0 0.00064 19.2 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 EOO00207.1 - 0.0027 17.7 0.0 0.034 14.1 0.0 2.3 1 1 0 1 1 1 1 NMT1/THI5 like NAPRTase_N PF17767.1 EOO00207.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain SRP54 PF00448.22 EOO00208.1 - 4.2e-76 255.0 2.2 1.4e-75 253.3 0.8 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EOO00208.1 - 2.1e-31 108.5 6.1 2.1e-31 108.5 6.1 3.5 3 1 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 EOO00208.1 - 5.4e-21 74.6 0.2 1.3e-20 73.4 0.2 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 EOO00208.1 - 5.4e-07 29.9 0.2 1.8e-06 28.1 0.0 2.0 3 0 0 3 3 1 1 AAA domain cobW PF02492.19 EOO00208.1 - 7.8e-07 28.9 0.8 4.1e-06 26.5 0.5 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 EOO00208.1 - 4.9e-05 23.8 0.8 0.00014 22.3 0.1 2.2 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EOO00208.1 - 0.00021 21.8 0.0 0.00044 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 EOO00208.1 - 0.00091 18.3 3.0 0.0019 17.3 0.9 2.4 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 EOO00208.1 - 0.001 18.4 0.0 0.0023 17.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 EOO00208.1 - 0.0011 18.8 1.0 0.0032 17.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 EOO00208.1 - 0.0016 18.2 0.1 0.021 14.5 0.0 2.4 2 0 0 2 2 2 1 Thymidylate kinase APS_kinase PF01583.20 EOO00208.1 - 0.0023 17.8 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase SRPRB PF09439.10 EOO00208.1 - 0.0027 17.2 0.9 3.1 7.2 0.8 3.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit CbiA PF01656.23 EOO00208.1 - 0.0028 17.7 0.0 0.0085 16.1 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 EOO00208.1 - 0.0058 17.2 0.0 0.013 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EOO00208.1 - 0.0067 16.4 0.3 0.035 14.1 0.3 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.17 EOO00208.1 - 0.0071 16.1 0.2 0.044 13.6 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EOO00208.1 - 0.0072 16.4 0.2 0.11 12.6 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EOO00208.1 - 0.0093 16.2 0.0 0.029 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 EOO00208.1 - 0.013 15.4 0.1 0.044 13.7 0.0 2.0 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 EOO00208.1 - 0.014 15.7 0.1 0.03 14.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EOO00208.1 - 0.024 15.0 0.1 0.064 13.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 EOO00208.1 - 0.036 13.0 0.0 0.078 11.9 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain 6PF2K PF01591.18 EOO00208.1 - 0.041 13.2 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA PF00004.29 EOO00208.1 - 0.095 13.1 0.2 0.36 11.2 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.21 EOO00208.1 - 0.12 11.8 0.1 0.4 10.1 0.0 1.8 2 0 0 2 2 1 0 ADP-ribosylation factor family NTPase_1 PF03266.15 EOO00208.1 - 0.14 12.0 0.6 0.66 9.9 0.6 2.1 1 1 0 1 1 1 0 NTPase Torsin PF06309.11 EOO00208.1 - 0.17 12.0 0.0 0.44 10.7 0.0 1.6 1 1 0 1 1 1 0 Torsin SKA2 PF16740.5 EOO00208.1 - 0.24 11.2 3.3 10 5.9 1.8 2.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Fungal_trans PF04082.18 EOO00209.1 - 5e-19 68.4 0.0 9.1e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EOO00210.1 - 4.2e-34 118.0 22.6 4.2e-34 118.0 22.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_S15 PF02129.18 EOO00212.1 - 2.8e-40 138.6 0.3 3.7e-40 138.2 0.3 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EOO00212.1 - 0.01 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PepX_C PF08530.10 EOO00212.1 - 0.013 15.4 0.1 0.031 14.2 0.1 1.6 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain DUF5490 PF17593.2 EOO00212.1 - 0.095 12.7 1.7 0.15 12.1 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5490) Peptidase_S9 PF00326.21 EOO00212.1 - 0.12 11.8 0.3 0.22 11.0 0.3 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydantoinase_B PF02538.14 EOO00213.1 - 1.3e-179 597.9 0.4 2.3e-179 597.1 0.4 1.4 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EOO00213.1 - 2.1e-93 312.8 0.0 6.6e-93 311.1 0.0 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EOO00213.1 - 1e-51 175.1 3.1 2e-50 171.0 0.1 2.7 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.9 EOO00213.1 - 0.093 12.4 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature PARP PF00644.20 EOO00214.1 - 4.6e-58 196.0 0.0 1.2e-57 194.6 0.0 1.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EOO00214.1 - 6.4e-43 146.1 0.1 1e-42 145.5 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EOO00214.1 - 9.8e-24 83.2 0.6 9.8e-24 83.2 0.6 1.9 2 0 0 2 2 2 1 WGR domain BRCT PF00533.26 EOO00214.1 - 9.2e-12 45.2 0.0 2.2e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EOO00214.1 - 4.5e-07 29.7 0.0 8.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 EOO00214.1 - 0.0066 16.8 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 EOO00214.1 - 0.1 12.7 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain SWIRM-assoc_2 PF16496.5 EOO00214.1 - 0.76 8.6 9.3 0.011 14.6 1.8 1.6 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal Glyco_hydro_76 PF03663.14 EOO00215.1 - 2.8e-144 481.1 18.2 3.3e-144 480.9 18.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Mem_trans PF03547.18 EOO00216.1 - 3.7e-05 22.3 0.1 4.4e-05 22.0 0.1 1.0 1 0 0 1 1 1 1 Membrane transport protein DUF4112 PF13430.6 EOO00216.1 - 0.028 14.7 0.2 0.034 14.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) Fungal_trans_2 PF11951.8 EOO00217.1 - 5.2e-17 61.7 2.5 2.9e-16 59.3 2.5 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain MIT PF04212.18 EOO00217.1 - 0.05 13.7 0.2 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF2834 PF11196.8 EOO00218.1 - 0.064 13.6 15.6 0.81 10.1 0.0 3.6 3 2 1 4 4 4 0 Protein of unknown function (DUF2834) Ribosomal_L1 PF00687.21 EOO00219.1 - 3.9e-25 88.8 0.2 4.8e-25 88.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DIOX_N PF14226.6 EOO00220.1 - 1.1e-31 110.1 0.0 1.7e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EOO00220.1 - 7.8e-22 77.7 0.0 1.5e-20 73.6 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SUa-2TM PF18179.1 EOO00220.1 - 0.052 12.8 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 SMODS- and Ubiquitin system-associated 2TM effector domain F-box PF00646.33 EOO00221.1 - 0.00066 19.5 0.3 0.0018 18.1 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EOO00221.1 - 0.012 15.5 0.1 0.043 13.7 0.1 1.9 2 0 0 2 2 2 0 F-box F-box-like PF12937.7 EOO00221.1 - 0.013 15.4 2.0 0.023 14.6 0.4 2.2 2 0 0 2 2 2 0 F-box-like E1-E2_ATPase PF00122.20 EOO00222.1 - 4.2e-36 124.1 0.9 7.9e-36 123.3 0.9 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EOO00222.1 - 2e-25 90.3 0.5 6.2e-13 49.5 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EOO00222.1 - 1e-14 54.3 0.0 2.4e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 EOO00222.1 - 4.1e-14 52.7 0.1 4.1e-14 52.7 0.1 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 EOO00222.1 - 0.00033 20.5 0.5 0.0013 18.6 0.3 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EOO00222.1 - 0.02 15.3 0.0 0.35 11.2 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PGG PF13962.6 EOO00222.1 - 0.05 13.4 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function S10_plectin PF03501.15 EOO00222.1 - 0.16 12.0 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Plectin/S10 domain LEP503 PF15221.6 EOO00222.1 - 0.18 12.2 0.1 0.79 10.1 0.1 2.1 2 0 0 2 2 2 0 Lens epithelial cell protein LEP503 Hydantoinase_B PF02538.14 EOO00223.1 - 6.4e-217 721.0 0.1 7.4e-217 720.8 0.1 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Proteasome_A_N PF10584.9 EOO00223.1 - 0.018 14.7 0.1 0.036 13.7 0.1 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature 2OG-FeII_Oxy PF03171.20 EOO00224.1 - 2e-18 66.7 0.0 2.8e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 EOO00225.1 - 1.1e-12 47.6 17.0 1.5e-12 47.1 17.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1772 PF08592.11 EOO00225.1 - 1.3 9.3 6.9 1.3 9.3 0.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) Fungal_trans_2 PF11951.8 EOO00226.1 - 0.032 13.1 0.3 0.038 12.8 0.3 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain adh_short_C2 PF13561.6 EOO00227.1 - 8.5e-60 202.2 1.8 1e-59 202.0 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO00227.1 - 1.6e-42 145.2 1.3 2.1e-42 144.8 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO00227.1 - 3.4e-09 36.9 2.5 6.9e-09 35.9 2.5 1.5 1 1 0 1 1 1 1 KR domain ETX_MTX2 PF03318.13 EOO00227.1 - 0.14 11.9 0.2 11 5.7 0.1 2.0 2 0 0 2 2 2 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 SAM_decarbox PF01536.16 EOO00228.1 - 8.4e-133 442.8 0.0 1e-132 442.5 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Cyt-b5 PF00173.28 EOO00229.1 - 5.8e-16 58.4 0.1 2e-15 56.6 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 EOO00229.1 - 3.5e-06 27.0 2.8 5.6e-06 26.4 2.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Ribosomal_L27 PF01016.19 EOO00230.1 - 7.3e-27 93.2 0.1 1.9e-26 91.9 0.1 1.7 1 0 0 1 1 1 1 Ribosomal L27 protein ECR1_N PF14382.6 EOO00230.1 - 0.15 11.9 0.2 0.3 10.9 0.2 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region FAM165 PF14981.6 EOO00230.1 - 2.6 7.9 6.6 7.5 6.4 6.6 1.8 1 0 0 1 1 1 0 FAM165 family DLH PF01738.18 EOO00231.1 - 8.4e-11 41.8 0.0 9.4e-11 41.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EOO00231.1 - 0.0012 18.6 0.0 0.0016 18.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold TauD PF02668.16 EOO00232.1 - 1e-52 179.6 0.0 1.2e-52 179.4 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CRAL_TRIO_2 PF13716.6 EOO00232.1 - 0.13 12.4 0.0 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain Fer2 PF00111.27 EOO00234.1 - 4.3e-13 49.0 0.8 5.9e-13 48.6 0.8 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PAP2 PF01569.21 EOO00235.1 - 1.2e-25 89.9 4.5 1.2e-25 89.9 0.9 2.2 1 1 1 2 2 2 1 PAP2 superfamily DUF983 PF06170.12 EOO00235.1 - 5.2 7.5 6.9 13 6.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Rrp15p PF07890.12 EOO00236.1 - 8.8e-39 132.9 7.1 8.8e-39 132.9 7.1 2.1 2 0 0 2 2 2 1 Rrp15p Toprim_4 PF13662.6 EOO00236.1 - 0.018 15.5 0.2 0.061 13.8 0.2 1.9 1 0 0 1 1 1 0 Toprim domain ThuA PF06283.11 EOO00236.1 - 0.087 13.0 0.3 0.15 12.2 0.3 1.3 1 0 0 1 1 1 0 Trehalose utilisation Adap_comp_sub PF00928.21 EOO00237.1 - 6.9e-91 304.3 0.0 1.2e-90 303.5 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EOO00237.1 - 1.4e-08 34.8 0.2 2.4e-08 34.0 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain 2-Hacid_dh_C PF02826.19 EOO00238.1 - 8.8e-35 119.7 0.0 1.5e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EOO00238.1 - 1.5e-10 40.9 0.0 2.3e-09 37.0 0.0 2.7 3 1 0 4 4 4 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EOO00238.1 - 1.9e-07 31.4 0.0 3.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Lyase_1 PF00206.20 EOO00239.1 - 3.2e-26 92.5 0.0 4e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Lyase FAA_hydrolase PF01557.18 EOO00240.1 - 2.5e-53 181.0 0.0 2.9e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family NADH5_C PF06455.11 EOO00241.1 - 0.042 13.4 0.1 0.042 13.4 0.1 2.0 3 0 0 3 3 3 0 NADH dehydrogenase subunit 5 C-terminus MFS_1 PF07690.16 EOO00242.1 - 1.1e-26 93.6 40.6 1.1e-26 93.6 40.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EOO00242.1 - 1.1e-06 28.2 7.6 1.1e-06 28.2 7.6 2.5 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF2721 PF11026.8 EOO00242.1 - 0.0087 16.0 3.4 0.0087 16.0 3.4 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF2721) CDC14 PF08045.11 EOO00242.1 - 0.031 13.4 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Cell division control protein 14, SIN component DUF1180 PF06679.12 EOO00242.1 - 0.091 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Saf_2TM PF18303.1 EOO00242.1 - 0.36 10.4 5.2 2.5 7.7 0.1 2.7 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain Phage_holin_5_2 PF16079.5 EOO00242.1 - 3.6 8.0 8.8 0.81 10.1 0.2 4.0 4 2 1 5 5 5 0 Phage holin family Hol44, in holin superfamily V SnoaL PF07366.12 EOO00243.1 - 0.0014 18.4 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EOO00243.1 - 0.006 17.2 0.0 0.022 15.4 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like domain Methyltransf_24 PF13578.6 EOO00244.1 - 7.8e-13 49.4 0.0 1.2e-12 48.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EOO00244.1 - 1.8e-07 30.6 0.0 2.5e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase DUF1442 PF07279.11 EOO00244.1 - 1.8e-06 27.5 0.0 2.4e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1442) Glyco_hydro_6 PF01341.17 EOO00245.1 - 1e-104 350.6 0.1 1.4e-104 350.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 COG2 PF06148.11 EOO00246.1 - 4.3e-18 65.7 0.1 1.4e-17 64.0 0.0 1.9 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 EOO00246.1 - 0.0071 16.4 0.0 0.017 15.2 0.0 1.8 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.12 EOO00246.1 - 0.11 11.2 0.0 0.22 10.2 0.0 1.5 2 0 0 2 2 2 0 Dor1-like family MFS_1 PF07690.16 EOO00247.1 - 4.6e-14 52.1 19.9 2.5e-13 49.7 20.1 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3180 PF11377.8 EOO00247.1 - 0.14 12.3 0.2 0.14 12.3 0.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) Mito_carr PF00153.27 EOO00248.1 - 2.7e-13 49.7 4.0 0.0002 21.2 0.0 4.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Ectatomin PF06457.11 EOO00248.1 - 0.085 12.8 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Ectatomin Thymidylate_kin PF02223.17 EOO00249.1 - 1.2e-42 145.7 0.0 6.3e-41 140.1 0.0 2.0 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 EOO00249.1 - 0.00062 20.1 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EOO00249.1 - 0.008 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 PRK PF00485.18 EOO00249.1 - 0.034 13.9 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 EOO00249.1 - 0.039 13.8 0.0 0.47 10.3 0.0 2.2 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein MeaB PF03308.16 EOO00249.1 - 0.046 12.7 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EOO00249.1 - 0.057 14.0 0.0 0.1 13.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 EOO00250.1 - 4.9e-07 29.0 9.9 8.7e-06 24.9 9.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 EOO00251.1 - 1.4e-31 109.7 30.3 1.4e-31 109.7 30.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily S_4TM PF18159.1 EOO00251.1 - 4.6 6.5 8.0 2.8 7.2 0.7 3.1 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain ParA PF10609.9 EOO00252.1 - 4.3e-91 304.7 0.1 5.2e-91 304.5 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EOO00252.1 - 1.3e-10 41.4 0.0 4.3e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EOO00252.1 - 1.9e-06 27.4 0.0 2.1e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 EOO00252.1 - 3.3e-05 23.9 0.1 0.0009 19.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 EOO00252.1 - 3.3e-05 23.2 0.7 8.9e-05 21.8 0.4 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 EOO00252.1 - 0.0016 17.5 0.4 0.0026 16.8 0.4 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 EOO00252.1 - 0.0039 16.8 0.2 0.0082 15.7 0.2 1.4 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 EOO00252.1 - 0.026 14.0 0.6 0.07 12.6 0.6 1.8 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 EOO00252.1 - 0.034 14.0 0.9 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EOO00252.1 - 0.096 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 EOO00252.1 - 0.1 11.8 0.1 0.26 10.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 EOO00252.1 - 0.18 12.2 0.4 0.46 10.8 0.4 1.6 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EOO00252.1 - 0.26 11.2 2.7 0.42 10.5 1.5 1.8 2 0 0 2 2 2 0 RsgA GTPase Sugar_tr PF00083.24 EOO00253.1 - 6.4e-68 229.7 15.7 1.5e-60 205.3 10.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO00253.1 - 3.5e-10 39.3 24.3 9.6e-09 34.6 23.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EOO00253.1 - 0.00019 20.4 3.7 0.00019 20.4 3.7 2.3 2 1 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 EOO00253.1 - 0.00035 19.3 1.2 0.00035 19.3 1.2 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein Aldedh PF00171.22 EOO00254.1 - 1.3e-131 439.3 1.3 1.4e-131 439.2 1.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EOO00254.1 - 5.7e-05 22.3 0.0 9.4e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 EOO00254.1 - 0.00095 18.7 0.0 0.77 9.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Choline_transpo PF04515.12 EOO00255.1 - 4e-83 279.3 21.3 4e-83 279.3 21.3 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter MgtC PF02308.16 EOO00255.1 - 0.17 12.3 14.9 0.11 12.8 1.2 4.0 3 2 1 4 4 4 0 MgtC family Pex14_N PF04695.13 EOO00255.1 - 0.2 12.3 7.2 0.4 11.3 7.2 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TAFII28 PF04719.14 EOO00257.1 - 3e-25 88.1 0.1 4.6e-16 58.7 0.0 2.5 2 0 0 2 2 2 2 hTAFII28-like protein conserved region Dala_Dala_lig_C PF07478.13 EOO00257.1 - 0.039 13.5 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus COesterase PF00135.28 EOO00259.1 - 2.8e-72 244.2 0.0 3.6e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EOO00259.1 - 1e-06 28.8 0.1 2.6e-06 27.5 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EOO00259.1 - 0.019 14.4 0.1 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EOO00259.1 - 0.076 13.6 0.1 0.13 12.9 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family 6PF2K PF01591.18 EOO00260.1 - 2.4e-80 269.0 0.1 3.3e-80 268.6 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EOO00260.1 - 4.6e-36 124.3 0.0 7.4e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EOO00260.1 - 3.9e-08 33.6 0.1 7.4e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EOO00260.1 - 0.00017 21.1 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Peptidase_M43 PF05572.13 EOO00261.1 - 3.4e-17 62.7 1.2 5.9e-17 62.0 1.2 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EOO00261.1 - 2.6e-07 31.0 1.6 4.2e-07 30.3 1.5 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EOO00261.1 - 1.5e-06 28.8 0.1 3.5e-06 27.5 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EOO00261.1 - 0.00037 20.2 4.4 0.0011 18.7 4.4 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EOO00261.1 - 0.00068 18.7 1.8 0.00093 18.2 1.8 1.3 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_2 PF13574.6 EOO00261.1 - 0.0011 19.0 1.8 0.0021 18.0 1.4 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Orthopox_A43R PF06517.11 EOO00261.1 - 0.0017 18.2 0.2 0.0027 17.6 0.2 1.3 1 0 0 1 1 1 1 Orthopoxvirus A43R protein Peptidase_M10 PF00413.24 EOO00261.1 - 0.0037 17.1 0.0 0.0063 16.4 0.0 1.5 1 1 0 1 1 1 1 Matrixin DUF4953 PF16313.5 EOO00261.1 - 0.051 12.8 0.1 0.098 11.8 0.1 1.4 1 0 0 1 1 1 0 Met-zincin Peptidase_M54 PF07998.11 EOO00261.1 - 0.058 13.4 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Peptidase family M54 Sugar_tr PF00083.24 EOO00262.1 - 4.3e-84 283.0 18.4 4.8e-84 282.8 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO00262.1 - 3.4e-36 124.9 47.4 1.2e-32 113.2 26.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EOO00262.1 - 0.087 11.7 13.3 0.036 12.9 2.2 2.5 2 1 0 2 2 2 0 MFS_1 like family DUF4538 PF15061.6 EOO00262.1 - 0.17 11.7 0.4 0.46 10.2 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF3021 PF11457.8 EOO00262.1 - 8.1 6.8 27.2 0.15 12.4 2.2 3.6 2 2 2 4 4 4 0 Protein of unknown function (DUF3021) AAA PF00004.29 EOO00263.1 - 2.9e-18 66.6 0.0 5.5e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EOO00263.1 - 6.1e-05 23.3 0.3 0.0024 18.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EOO00263.1 - 0.00053 20.4 0.0 0.002 18.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EOO00263.1 - 0.0075 16.3 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EOO00263.1 - 0.032 13.9 0.4 0.094 12.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EOO00263.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EOO00263.1 - 0.057 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EOO00263.1 - 0.061 12.7 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EOO00263.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DIOX_N PF14226.6 EOO00264.1 - 5.4e-23 82.0 0.0 8.9e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EOO00264.1 - 1.9e-22 79.6 0.0 6e-22 78.0 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Tyrosinase PF00264.20 EOO00265.1 - 3.3e-47 161.6 0.0 4.6e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase OmdA PF13376.6 EOO00265.1 - 0.2 11.7 0.3 2.1 8.4 0.0 2.6 3 1 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated Epimerase PF01370.21 EOO00266.1 - 1.2e-12 47.9 0.0 4.2e-12 46.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO00266.1 - 1.5e-06 27.8 0.0 3.8e-05 23.2 0.0 2.7 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EOO00266.1 - 2.1e-06 27.0 0.0 3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EOO00266.1 - 0.00033 20.3 0.0 0.0008 19.0 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 EOO00266.1 - 0.00045 20.2 0.0 0.00077 19.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EOO00266.1 - 0.0032 16.7 0.0 0.0062 15.7 0.0 1.4 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 EOO00266.1 - 0.015 14.4 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.25 EOO00266.1 - 0.059 12.8 0.1 1.3 8.5 0.0 2.7 4 0 0 4 4 4 0 short chain dehydrogenase Bromodomain PF00439.25 EOO00267.1 - 1.1e-35 121.5 0.0 2e-19 69.4 0.1 2.7 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 EOO00267.1 - 1.4e-10 41.2 1.8 1.4e-10 41.2 1.8 2.4 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Folliculin PF11704.8 EOO00267.1 - 0.25 11.2 6.4 0.73 9.7 0.3 2.6 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF4567 PF15131.6 EOO00268.1 - 0.13 12.3 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) RTA1 PF04479.13 EOO00269.1 - 1.6e-69 233.7 9.0 2.4e-69 233.1 9.0 1.2 1 0 0 1 1 1 1 RTA1 like protein PalH PF08733.10 EOO00269.1 - 0.014 14.4 1.6 0.02 13.9 1.6 1.3 1 0 0 1 1 1 0 PalH/RIM21 DHHC PF01529.20 EOO00269.1 - 5.5 7.1 6.8 11 6.2 0.2 2.8 3 0 0 3 3 3 0 DHHC palmitoyltransferase DUF4064 PF13273.6 EOO00270.1 - 0.018 15.3 3.1 1.1 9.5 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) SNARE PF05739.19 EOO00272.1 - 1.4e-06 28.2 0.6 2.7e-06 27.3 0.6 1.5 1 0 0 1 1 1 1 SNARE domain DUF812 PF05667.11 EOO00272.1 - 0.0038 16.2 3.1 0.0065 15.4 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF812) Exonuc_VII_S PF02609.16 EOO00272.1 - 0.0091 16.0 1.0 1.9 8.6 0.1 2.4 2 0 0 2 2 2 2 Exonuclease VII small subunit Use1 PF09753.9 EOO00272.1 - 0.027 14.2 0.7 0.36 10.5 0.0 2.3 1 1 0 2 2 2 0 Membrane fusion protein Use1 CorA PF01544.18 EOO00272.1 - 0.1 11.9 5.5 0.21 10.9 0.1 2.4 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein HemX PF04375.14 EOO00272.1 - 0.14 11.4 6.8 0.44 9.8 1.4 2.2 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Snapin_Pallidin PF14712.6 EOO00272.1 - 0.32 11.5 3.6 14 6.2 1.1 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Sugar_tr PF00083.24 EOO00273.1 - 1.1e-29 103.6 9.8 1.2e-29 103.5 9.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO00273.1 - 4.5e-06 25.8 4.5 5.4e-06 25.6 4.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 EOO00273.1 - 0.11 12.6 0.5 0.19 11.8 0.2 1.7 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TPR_12 PF13424.6 EOO00274.1 - 6.1e-12 45.7 12.7 1.2e-06 28.7 0.1 4.6 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 EOO00274.1 - 4.5e-07 29.6 3.9 8.5e-07 28.6 3.9 1.4 1 0 0 1 1 1 1 MalT-like TPR region TPR_10 PF13374.6 EOO00274.1 - 6.1e-05 22.8 11.9 0.15 12.0 0.1 5.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EOO00274.1 - 0.00021 21.8 6.2 0.13 13.1 0.5 4.3 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EOO00274.1 - 0.00051 20.5 4.2 2.8 8.5 0.5 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EOO00274.1 - 0.004 17.2 10.3 0.39 10.9 0.2 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EOO00274.1 - 0.014 16.1 3.1 3 8.6 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EOO00274.1 - 0.027 14.7 9.3 1.4 9.4 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EOO00274.1 - 0.25 11.4 2.9 39 4.6 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EOO00274.1 - 2 9.3 5.5 5.7 7.9 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_42M PF08532.10 EOO00275.1 - 0.0003 20.4 0.0 0.0014 18.1 0.0 2.0 3 0 0 3 3 3 1 Beta-galactosidase trimerisation domain Glyco_hydro_106 PF17132.4 EOO00275.1 - 0.00044 18.7 0.0 0.0012 17.2 0.0 1.7 1 1 0 1 1 1 1 alpha-L-rhamnosidase DNA_pol_phi PF04931.13 EOO00276.1 - 0.076 11.1 17.1 0.091 10.9 17.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 EOO00276.1 - 0.6 9.8 4.8 1.2 8.8 4.8 1.5 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.12 EOO00276.1 - 1.2 8.5 14.4 1.4 8.3 14.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EOO00276.1 - 1.4 7.0 12.5 1.7 6.8 12.5 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2722 PF10846.8 EOO00276.1 - 5.7 5.8 9.4 7.4 5.4 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Astro_capsid_p PF12226.8 EOO00276.1 - 7.6 5.6 10.7 9.3 5.3 10.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein BUD22 PF09073.10 EOO00276.1 - 8.2 5.6 10.4 9.8 5.4 10.4 1.1 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 EOO00276.1 - 8.8 5.3 28.8 13 4.8 28.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PhyH PF05721.13 EOO00279.1 - 4.8e-14 53.1 0.0 7.8e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EOO00279.1 - 6.8e-08 31.7 0.0 8.8e-05 21.4 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.6 EOO00279.1 - 0.0024 18.7 0.0 0.0061 17.4 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Utp12 PF04003.12 EOO00280.1 - 1.4e-24 86.4 0.6 2.9e-24 85.5 0.6 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family SDA1 PF05285.12 EOO00280.1 - 1.6 8.1 26.9 0.17 11.3 16.5 2.1 2 0 0 2 2 2 0 SDA1 ELO PF01151.18 EOO00281.1 - 3.2e-50 171.0 11.6 4.6e-26 91.9 4.7 2.0 1 1 1 2 2 2 2 GNS1/SUR4 family UPF0182 PF03699.13 EOO00281.1 - 0.1 10.7 4.4 0.15 10.2 4.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) MatC_N PF07158.11 EOO00281.1 - 3.9 7.5 5.8 3.3 7.7 3.6 1.8 1 1 1 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus Transp_cyt_pur PF02133.15 EOO00282.1 - 5.3e-41 140.8 13.6 6.6e-41 140.5 13.6 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin p450 PF00067.22 EOO00284.1 - 5.3e-22 78.2 0.0 7e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pilin_N PF07790.11 EOO00285.1 - 0.013 16.4 0.1 0.036 15.0 0.1 1.8 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DUF4834 PF16118.5 EOO00285.1 - 0.051 14.5 0.0 0.099 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CTP_transf_1 PF01148.20 EOO00285.1 - 0.058 13.2 0.1 0.085 12.6 0.1 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family EphA2_TM PF14575.6 EOO00285.1 - 0.15 13.0 0.0 0.26 12.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SNARE PF05739.19 EOO00285.1 - 0.41 10.7 1.5 0.75 9.8 1.5 1.3 1 0 0 1 1 1 0 SNARE domain AF-4 PF05110.13 EOO00285.1 - 3 5.8 9.3 4 5.4 9.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GATase_5 PF13507.6 EOO00287.1 - 1.1e-102 342.6 0.0 1.6e-102 342.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EOO00287.1 - 2.1e-33 115.7 0.2 1e-23 84.2 0.1 2.8 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EOO00287.1 - 1.5e-25 89.4 0.0 2.6e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EOO00287.1 - 8.3e-23 80.7 0.0 1.9e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain DUF3378 PF11858.8 EOO00287.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) Amidase PF01425.21 EOO00288.1 - 1.4e-26 93.5 0.0 1.5e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 Amidase p450 PF00067.22 EOO00289.1 - 4.7e-14 52.0 0.0 6e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Asp PF00026.23 EOO00290.1 - 1.3e-38 133.2 1.0 1.9e-38 132.7 1.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EOO00290.1 - 0.00041 20.9 0.1 0.9 10.2 0.0 3.6 4 0 0 4 4 4 1 Aspartyl protease TAXi_C PF14541.6 EOO00290.1 - 0.00079 19.2 0.2 0.0072 16.1 0.1 2.5 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EOO00290.1 - 0.033 14.7 0.0 16 6.1 0.0 3.6 4 0 0 4 4 4 0 gag-polyprotein putative aspartyl protease Glyco_hydro_130 PF04041.13 EOO00291.1 - 0.00017 20.6 0.0 0.00049 19.1 0.0 1.7 2 0 0 2 2 2 1 beta-1,4-mannooligosaccharide phosphorylase ADP_ribosyl_GH PF03747.14 EOO00292.1 - 1.8e-49 169.0 0.8 2.6e-49 168.5 0.8 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Sugar_tr PF00083.24 EOO00293.1 - 1.9e-118 396.2 31.6 2.2e-118 396.0 31.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO00293.1 - 8.3e-20 71.0 66.7 2.9e-17 62.6 37.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EOO00293.1 - 0.03 12.9 28.6 0.073 11.6 13.1 2.7 2 1 0 2 2 2 0 MFS/sugar transport protein TRI12 PF06609.13 EOO00293.1 - 0.034 12.6 12.0 0.045 12.2 2.8 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Pentapeptide_4 PF13599.6 EOO00295.1 - 0.027 14.6 0.7 0.054 13.7 0.7 1.5 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Ribosomal_L28 PF00830.19 EOO00296.1 - 7.9e-22 77.2 2.2 1.3e-21 76.5 2.2 1.3 1 0 0 1 1 1 1 Ribosomal L28 family p450 PF00067.22 EOO00297.1 - 2.1e-65 221.3 0.0 2.8e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GFO_IDH_MocA PF01408.22 EOO00298.1 - 7.6e-17 62.3 0.1 1.2e-16 61.6 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EOO00298.1 - 0.006 17.2 0.1 0.0097 16.6 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Rossmann-like PF10727.9 EOO00298.1 - 0.025 14.4 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain Methyltransf_23 PF13489.6 EOO00299.1 - 8.4e-15 55.0 0.1 6.4e-14 52.1 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO00299.1 - 3.3e-06 27.0 0.0 0.0018 18.1 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EOO00299.1 - 0.0002 22.0 0.0 0.9 10.3 0.0 2.6 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EOO00299.1 - 0.0048 17.5 0.0 0.18 12.5 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 EOO00299.1 - 0.0085 15.6 0.0 0.058 12.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain PPTA PF01239.22 EOO00300.1 - 6.6e-35 117.8 5.6 2.5e-09 36.5 0.5 4.3 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat DUF3720 PF12517.8 EOO00300.1 - 0.093 13.7 3.6 0.18 12.7 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) DUF1674 PF07896.12 EOO00302.1 - 1.2e-19 70.5 1.2 3.1e-19 69.2 1.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) KH_1 PF00013.29 EOO00303.1 - 6.8e-47 157.2 11.1 2.8e-16 59.1 1.5 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EOO00303.1 - 1.2e-10 41.1 5.0 0.02 14.7 0.2 3.6 4 0 0 4 4 4 3 KH domain KH_4 PF13083.6 EOO00303.1 - 6.2e-10 38.8 2.6 0.083 12.8 0.0 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 EOO00303.1 - 0.00044 20.2 0.0 0.56 10.3 0.0 2.9 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_5 PF13184.6 EOO00303.1 - 0.035 14.2 3.9 9.6 6.4 0.1 3.3 3 0 0 3 3 3 0 NusA-like KH domain HET PF06985.11 EOO00304.1 - 3.2e-28 98.9 0.7 6.2e-28 98.0 0.7 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Spherulin4 PF12138.8 EOO00305.1 - 1.8e-43 149.0 1.0 2.1e-43 148.7 1.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 DUF829 PF05705.14 EOO00306.1 - 2.6e-35 122.5 0.0 3.2e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Trp_syntA PF00290.20 EOO00307.1 - 3.9e-99 330.7 0.0 6.9e-99 329.9 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EOO00307.1 - 3.4e-49 167.8 1.4 5.3e-49 167.2 1.4 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PcrB PF01884.17 EOO00307.1 - 0.028 13.9 0.1 0.094 12.2 0.0 1.8 2 0 0 2 2 2 0 PcrB family CLN3 PF02487.17 EOO00308.1 - 1.3e-93 314.2 0.0 1.5e-93 314.0 0.0 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 EOO00308.1 - 0.0024 16.9 8.2 0.0032 16.5 8.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4637 PF15470.6 EOO00308.1 - 0.052 13.3 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF3433 PF11915.8 EOO00309.1 - 1.3e-09 38.3 0.4 1.3e-09 38.3 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) MFS_1 PF07690.16 EOO00311.1 - 5.6e-12 45.3 21.7 5.6e-12 45.3 21.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EOO00311.1 - 8.7e-05 22.3 6.2 8.7e-05 22.3 6.2 2.8 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 EOO00311.1 - 0.0044 15.9 10.6 0.0044 15.9 10.6 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter Exo_endo_phos PF03372.23 EOO00312.1 - 0.00043 19.9 0.0 0.0025 17.3 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DEAD PF00270.29 EOO00313.1 - 4.7e-47 160.0 0.0 1.4e-46 158.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EOO00313.1 - 9.7e-25 87.1 0.0 5.2e-24 84.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EOO00313.1 - 1.1e-19 70.4 0.2 2.7e-19 69.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EOO00313.1 - 0.00034 20.7 0.0 0.00065 19.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EOO00313.1 - 0.00064 19.0 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase BSP_II PF05432.11 EOO00313.1 - 0.12 12.1 8.7 0.18 11.5 8.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PNISR PF15996.5 EOO00313.1 - 2.2 8.5 9.6 4 7.7 9.6 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Nop14 PF04147.12 EOO00313.1 - 3.9 5.6 11.5 5.2 5.1 11.5 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EOO00313.1 - 6.3 4.8 17.5 11 4.0 17.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi adh_short PF00106.25 EOO00315.1 - 3.6e-15 56.0 0.0 4.4e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO00315.1 - 2.1e-14 53.7 0.0 2.6e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO00315.1 - 7e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EOO00315.1 - 0.074 12.9 0.0 0.1 12.5 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EOO00315.1 - 0.095 11.8 0.0 0.33 10.0 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sugar_tr PF00083.24 EOO00316.1 - 3.9e-82 276.5 20.2 4.5e-82 276.3 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO00316.1 - 1.1e-17 64.1 27.1 1.1e-17 64.1 27.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Stc1 PF12898.7 EOO00316.1 - 0.02 15.5 0.1 0.036 14.6 0.1 1.3 1 0 0 1 1 1 0 Stc1 domain DUF4605 PF15378.6 EOO00316.1 - 0.067 13.1 2.0 0.15 11.9 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) AA_permease_2 PF13520.6 EOO00317.1 - 1.1e-18 67.2 15.0 5.5e-18 65.0 14.1 2.0 1 1 0 1 1 1 1 Amino acid permease DUF418 PF04235.12 EOO00317.1 - 0.06 13.3 9.0 0.37 10.7 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF418) DUF202 PF02656.15 EOO00317.1 - 1.1 9.7 9.1 9.6 6.7 0.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF202) MFS_1 PF07690.16 EOO00318.1 - 5.9e-32 111.0 19.1 5.9e-32 111.0 19.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Cnn_1N PF07989.11 EOO00319.1 - 3.7e-08 33.4 12.2 3.7e-08 33.4 12.2 2.2 2 1 0 2 2 2 1 Centrosomin N-terminal motif 1 AAA_23 PF13476.6 EOO00319.1 - 0.22 12.0 6.4 0.11 13.0 2.7 2.1 2 0 0 2 2 2 0 AAA domain BRF1 PF07741.13 EOO00319.1 - 3.9 7.9 7.2 0.58 10.5 0.9 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain HalX PF08663.10 EOO00319.1 - 5 7.5 10.7 21 5.5 10.7 2.1 1 1 0 1 1 1 0 HalX domain TEX13 PF15186.6 EOO00319.1 - 8.6 6.0 11.0 3 7.5 8.0 1.7 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family HOCHOB PF17943.1 EOO00320.1 - 0.0077 16.9 0.0 0.013 16.2 0.0 1.3 1 0 0 1 1 1 1 Homeobox-cysteine loop-homeobox ATP_bind_3 PF01171.20 EOO00321.1 - 9.6e-38 129.7 0.0 6.8e-27 94.4 0.0 2.2 2 0 0 2 2 2 2 PP-loop family Asn_synthase PF00733.21 EOO00321.1 - 0.0072 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase Glyco_transf_4 PF13439.6 EOO00321.1 - 0.055 13.5 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 E1-E2_ATPase PF00122.20 EOO00322.1 - 1.4e-24 86.6 10.4 7.4e-18 64.7 0.0 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EOO00322.1 - 5.4e-23 81.6 11.0 5.4e-23 81.6 11.0 2.1 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EOO00322.1 - 1.2e-17 64.9 0.0 5.7e-16 59.4 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EOO00322.1 - 2.2e-17 62.9 0.0 6.8e-17 61.3 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EOO00322.1 - 0.00017 21.4 0.1 0.0027 17.5 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GSDH PF07995.11 EOO00323.1 - 0.00048 19.5 0.1 0.00078 18.8 0.1 1.4 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SGL PF08450.12 EOO00323.1 - 0.017 14.7 0.1 0.061 12.9 0.0 1.9 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 EOO00323.1 - 0.071 13.1 0.0 0.27 11.2 0.0 2.0 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat PRKCSH PF07915.13 EOO00324.1 - 2.7e-17 63.6 0.7 7.7e-17 62.1 0.7 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DNA_pol_B_thumb PF14791.6 EOO00324.1 - 0.011 15.9 0.5 0.054 13.7 0.2 2.2 2 0 0 2 2 2 0 DNA polymerase beta thumb Aminotran_1_2 PF00155.21 EOO00325.1 - 1.4e-92 310.7 0.0 2.2e-92 310.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4663 PF15668.5 EOO00325.1 - 0.076 12.1 0.3 0.13 11.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) TRI12 PF06609.13 EOO00326.1 - 1.6e-27 96.2 12.0 1.9e-27 96.0 12.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EOO00326.1 - 0.003 16.5 26.8 0.035 13.1 26.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3040 PF11239.8 EOO00326.1 - 0.12 12.6 0.1 0.12 12.6 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) DUF3784 PF12650.7 EOO00326.1 - 6.1 7.1 14.4 0.15 12.2 1.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) Saf_2TM PF18303.1 EOO00327.1 - 0.14 11.7 4.2 0.31 10.6 0.3 2.9 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain PspB PF06667.12 EOO00327.1 - 0.17 12.0 0.3 1.4 9.1 0.1 2.4 2 0 0 2 2 2 0 Phage shock protein B Sigma_reg_N PF13800.6 EOO00327.1 - 1.3 9.3 4.1 4.7 7.6 0.2 3.0 3 0 0 3 3 3 0 Sigma factor regulator N-terminal adh_short PF00106.25 EOO00328.1 - 8.7e-19 67.7 0.0 1e-13 51.2 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EOO00328.1 - 5e-09 36.1 0.0 5.1e-06 26.2 0.0 2.7 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO00328.1 - 1.1e-07 32.0 0.0 2.6e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EOO00328.1 - 0.00056 19.1 0.0 0.00093 18.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 EOO00328.1 - 0.19 11.5 0.3 0.32 10.8 0.3 1.3 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Amdase PF17645.1 EOO00329.1 - 2.2e-18 66.7 0.1 3e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 EOO00329.1 - 1.5e-06 28.2 0.0 1.8e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DPBB_1 PF03330.18 EOO00329.1 - 0.001 19.3 0.1 0.0021 18.3 0.1 1.6 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EOO00329.1 - 0.09 12.6 0.1 0.61 9.9 0.1 2.3 2 0 0 2 2 2 0 Barwin family HCV_NS5a_1b PF08301.13 EOO00330.1 - 0.021 15.4 0.3 1.5 9.4 0.0 2.8 3 0 0 3 3 3 0 Hepatitis C virus non-structural 5a domain 1b SpoIIIAH PF12685.7 EOO00331.1 - 2 8.2 9.7 7.3 6.4 3.9 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Vfa1 PF08432.10 EOO00331.1 - 2.8 8.2 17.7 2.8 8.2 9.1 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Sugar_tr PF00083.24 EOO00332.1 - 0.0014 17.5 0.5 0.0016 17.4 0.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Mpp10 PF04006.12 EOO00333.1 - 6.9e-112 374.9 47.0 1.2e-111 374.1 47.0 1.3 1 0 0 1 1 1 1 Mpp10 protein MFS_1 PF07690.16 EOO00335.1 - 4.6e-33 114.6 59.4 6.2e-33 114.2 57.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO00335.1 - 7.7e-08 31.6 14.8 7.7e-08 31.6 14.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EOO00335.1 - 2.2 6.5 12.2 0.085 11.1 3.9 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SANT_DAMP1_like PF16282.5 EOO00336.1 - 1.6e-31 108.3 0.6 2.9e-31 107.5 0.6 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Formyl_trans_N PF00551.19 EOO00337.1 - 8e-22 77.8 0.0 3e-21 76.0 0.0 2.0 2 1 0 2 2 2 1 Formyl transferase MFS_1 PF07690.16 EOO00341.1 - 1.8e-46 158.7 24.8 2.2e-46 158.4 24.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO00341.1 - 1.2e-17 64.0 9.1 1.2e-17 64.0 9.1 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EOO00341.1 - 1.9e-05 23.3 2.5 3.1e-05 22.6 2.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.16 EOO00341.1 - 0.0025 17.6 0.3 0.0025 17.6 0.3 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 OATP PF03137.20 EOO00341.1 - 2.8 6.1 11.2 0.18 10.1 3.3 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family CIAPIN1 PF05093.13 EOO00342.1 - 4.8e-41 139.3 4.6 8.3e-41 138.6 4.6 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EOO00342.1 - 3.5e-39 134.1 0.0 4.8e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Aldo_ket_red PF00248.21 EOO00343.1 - 7e-71 238.8 0.0 8.7e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NMO PF03060.15 EOO00344.1 - 2.5e-35 122.5 10.7 4e-33 115.2 10.7 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EOO00344.1 - 1.2e-07 31.1 9.5 1e-05 24.7 9.5 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EOO00344.1 - 6.1e-07 28.8 7.3 9.1e-07 28.2 7.3 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EOO00344.1 - 0.00074 18.8 2.5 0.0011 18.2 2.5 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Oxidored_q6 PF01058.22 EOO00345.1 - 4.1e-22 78.4 0.0 6e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit HECT PF00632.25 EOO00346.1 - 5.9e-95 318.3 0.0 1e-94 317.5 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EOO00346.1 - 9.7e-24 83.2 16.5 5.1e-13 48.9 6.3 3.0 3 0 0 3 3 3 2 WW domain C2 PF00168.30 EOO00346.1 - 5.6e-21 74.8 0.0 1.6e-20 73.3 0.0 1.8 1 0 0 1 1 1 1 C2 domain Uteroglobin PF01099.17 EOO00346.1 - 0.14 12.5 0.1 6.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Uteroglobin family RRM_1 PF00076.22 EOO00347.1 - 9e-17 60.7 0.0 1.4e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spc7 PF08317.11 EOO00347.1 - 0.01 14.7 1.3 0.013 14.4 1.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 EOO00347.1 - 0.026 14.8 0.8 0.04 14.2 0.8 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup35_RRM_2 PF14605.6 EOO00347.1 - 0.037 14.0 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif NPV_P10 PF05531.12 EOO00347.1 - 0.057 13.9 0.4 0.11 13.0 0.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 EOO00347.1 - 0.1 12.4 2.4 0.14 11.9 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GPS2_interact PF15784.5 EOO00347.1 - 0.11 13.0 2.3 0.18 12.3 2.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain RRM_occluded PF16842.5 EOO00347.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif V_ATPase_I PF01496.19 EOO00347.1 - 0.12 10.2 0.6 0.15 10.0 0.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ZapB PF06005.12 EOO00347.1 - 0.24 11.9 6.2 0.41 11.1 6.2 1.2 1 0 0 1 1 1 0 Cell division protein ZapB Spc24 PF08286.11 EOO00347.1 - 0.26 11.6 2.2 0.37 11.1 2.2 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 TRAP_alpha PF03896.16 EOO00347.1 - 1.2 8.3 3.5 1.6 7.9 3.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit GRP PF07172.11 EOO00347.1 - 1.6 9.4 15.2 0.33 11.7 11.0 1.9 2 0 0 2 2 2 0 Glycine rich protein family Nuc_sug_transp PF04142.15 EOO00348.1 - 1.5e-27 96.6 18.8 4.4e-24 85.2 19.5 2.4 2 0 0 2 2 2 2 Nucleotide-sugar transporter Tom5 PF10642.9 EOO00348.1 - 0.22 11.6 1.3 1.3 9.1 0.4 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Adap_comp_sub PF00928.21 EOO00349.1 - 3.1e-69 233.3 0.0 3.8e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EOO00349.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain WD40 PF00400.32 EOO00350.1 - 1.7e-26 91.9 29.4 0.00043 21.0 0.2 11.2 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO00350.1 - 6.9e-14 51.9 3.3 0.002 18.4 0.1 5.8 3 3 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 EOO00350.1 - 0.015 14.6 0.0 0.19 11.0 0.0 2.6 3 1 0 3 3 3 0 CPSF A subunit region PD40 PF07676.12 EOO00350.1 - 0.11 12.4 7.8 16 5.5 0.0 5.1 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EOO00350.1 - 0.14 11.1 6.5 4.8 6.1 0.2 4.1 4 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DBP10CT PF08147.12 EOO00350.1 - 0.18 12.1 0.7 1.4 9.2 0.2 2.5 2 0 0 2 2 2 0 DBP10CT (NUC160) domain Peptidase_M23 PF01551.22 EOO00350.1 - 0.9 9.8 4.0 8.3 6.7 0.2 3.7 2 1 1 3 3 3 0 Peptidase family M23 Glyco_hydro_32N PF00251.20 EOO00351.1 - 7.5e-56 189.9 5.8 1.1e-55 189.4 5.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EOO00351.1 - 3.8e-08 33.5 0.4 8.3e-08 32.4 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Aldedh PF00171.22 EOO00352.1 - 3.6e-76 256.6 0.0 4.4e-76 256.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EOO00352.1 - 0.025 13.7 0.0 0.055 12.5 0.0 1.5 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Hexapep_2 PF14602.6 EOO00353.1 - 1.4e-17 63.1 24.1 9.3e-10 38.1 2.0 3.4 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 EOO00353.1 - 1.6e-17 62.5 24.3 6.5e-10 38.3 1.7 3.8 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EOO00353.1 - 0.026 13.5 0.1 0.051 12.5 0.1 1.6 1 1 1 2 2 2 0 L-fucokinase Ribosomal_L27 PF01016.19 EOO00353.1 - 0.067 13.2 0.3 2.2 8.4 0.0 2.7 2 1 1 3 3 3 0 Ribosomal L27 protein UAA PF08449.11 EOO00354.1 - 1.5e-10 40.8 14.2 2e-10 40.4 14.2 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EOO00354.1 - 0.00011 22.4 26.6 0.00019 21.6 7.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family Ycf66_N PF07444.11 EOO00354.1 - 1.8 8.8 6.1 2.3 8.4 0.9 3.3 3 0 0 3 3 3 0 Ycf66 protein N-terminus PHO4 PF01384.20 EOO00354.1 - 9.9 5.1 17.3 0.18 10.8 8.1 2.2 1 1 1 2 2 2 0 Phosphate transporter family SPX PF03105.19 EOO00355.1 - 0.012 15.5 1.0 0.012 15.5 1.0 3.4 2 1 2 4 4 4 0 SPX domain DUF3613 PF12266.8 EOO00355.1 - 0.085 12.7 0.2 0.3 10.9 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) Peptidase_S10 PF00450.22 EOO00356.1 - 6.4e-112 375.0 0.0 7.6e-112 374.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Fungus-induced PF10917.8 EOO00356.1 - 0.026 14.8 0.0 0.069 13.5 0.0 1.6 1 0 0 1 1 1 0 Fungus-induced protein DUF1206 PF06724.11 EOO00356.1 - 0.22 11.6 1.7 0.57 10.3 1.7 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Fungal_trans PF04082.18 EOO00357.1 - 1.4e-11 43.9 0.2 2.6e-11 43.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EOO00357.1 - 1.8e-06 27.9 8.9 3.4e-06 27.1 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pol_alpha_B_N PF08418.10 EOO00357.1 - 0.057 13.4 0.6 0.095 12.7 0.6 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal HypD PF01924.16 EOO00357.1 - 0.36 9.9 1.6 0.58 9.2 1.6 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family MSP1_C PF07462.11 EOO00357.1 - 0.5 9.0 4.1 0.31 9.7 2.4 1.4 1 1 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Glyoxalase PF00903.25 EOO00358.1 - 7.3e-06 26.2 0.0 2.4e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EOO00358.1 - 0.0033 18.2 0.0 0.0049 17.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain HABP4_PAI-RBP1 PF04774.15 EOO00359.1 - 0.17 12.7 3.7 0.27 12.1 3.7 1.5 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family NTP_transferase PF00483.23 EOO00360.1 - 9.7e-06 25.3 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase APH PF01636.23 EOO00360.1 - 6.5e-05 23.0 0.1 0.00015 21.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family NTP_transf_3 PF12804.7 EOO00360.1 - 0.0021 18.4 0.0 0.0051 17.2 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hydrolase_3 PF08282.12 EOO00360.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glyco_tran_28_C PF04101.16 EOO00361.1 - 4.1e-13 49.7 0.0 4e-07 30.2 0.1 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain MRP-S28 PF10213.9 EOO00362.1 - 4.8e-46 156.3 0.6 9.3e-46 155.4 0.2 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein Nucleoporin_C PF03177.14 EOO00363.1 - 7e-179 596.4 0.4 8.9e-179 596.0 0.4 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EOO00363.1 - 2.9e-72 243.8 0.0 3.7e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like SRC-1 PF08832.10 EOO00363.1 - 0.17 13.0 0.1 3 9.0 0.0 2.5 2 0 0 2 2 2 0 Steroid receptor coactivator ECR1_N PF14382.6 EOO00364.1 - 6.5e-18 64.3 1.2 2.1e-17 62.6 1.2 2.0 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EOO00364.1 - 5.6e-05 23.4 0.2 0.0001 22.6 0.2 1.4 1 0 0 1 1 1 1 KH domain EMP24_GP25L PF01105.24 EOO00365.1 - 1.9e-55 187.6 0.0 2.2e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FTP PF07504.13 EOO00366.1 - 7.8e-11 41.6 0.1 5.5e-10 38.9 0.1 1.9 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Polyhedrin PF00738.18 EOO00366.1 - 0.01 15.2 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 Polyhedrin EGF_CA PF07645.15 EOO00367.1 - 0.011 15.9 0.4 0.021 15.0 0.4 1.4 1 0 0 1 1 1 0 Calcium-binding EGF domain DUF4685 PF15737.5 EOO00367.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) EGF_3 PF12947.7 EOO00367.1 - 0.23 11.7 3.8 2.5 8.4 1.7 2.2 2 0 0 2 2 2 0 EGF domain EGF PF00008.27 EOO00367.1 - 5.5 7.4 8.4 1.4 9.3 2.9 2.2 2 0 0 2 2 2 0 EGF-like domain Med7 PF05983.11 EOO00368.1 - 3.9e-63 213.0 0.0 4.7e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 MED7 protein SIMPL PF04402.14 EOO00368.1 - 0.037 14.5 0.1 0.042 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Peptidase_S8 PF00082.22 EOO00369.1 - 0.015 14.5 0.1 0.016 14.4 0.1 1.1 1 0 0 1 1 1 0 Subtilase family Glyco_hydro_31 PF01055.26 EOO00370.1 - 7.9e-52 176.9 0.2 1e-51 176.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EOO00370.1 - 2.1e-15 56.8 0.2 4.2e-15 55.8 0.2 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like Proteasome PF00227.26 EOO00371.1 - 1.1e-60 204.4 0.1 1.5e-60 203.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EOO00371.1 - 2.4e-11 43.1 0.1 7.2e-11 41.6 0.2 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.14 EOO00371.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF5624 PF18538.1 EOO00371.1 - 0.03 14.4 0.1 0.073 13.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) PMM PF03332.13 EOO00372.1 - 3.6e-11 43.3 0.0 4.7e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EOO00372.1 - 2.3e-10 40.7 0.0 1.4e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EOO00372.1 - 0.0094 16.3 0.2 0.039 14.2 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3631 PF12307.8 EOO00372.1 - 0.041 14.1 0.0 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) S6PP PF05116.13 EOO00372.1 - 0.064 12.8 0.0 0.89 9.0 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.6 EOO00372.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.8 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Sugar_tr PF00083.24 EOO00373.1 - 2.3e-74 250.9 12.6 2.6e-74 250.7 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO00373.1 - 7.2e-12 44.9 22.7 5.1e-09 35.5 6.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_31 PF01055.26 EOO00374.1 - 9.8e-18 64.6 0.0 1.2e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 PAP2 PF01569.21 EOO00375.1 - 3.3e-26 91.7 0.3 3.3e-26 91.7 0.3 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EOO00375.1 - 0.011 15.5 2.3 0.011 15.5 2.3 2.6 2 1 0 2 2 2 0 PAP2 superfamily DUF2053 PF09767.9 EOO00375.1 - 0.091 12.9 0.2 1.1 9.3 0.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2053) HisKA_7TM PF16927.5 EOO00375.1 - 0.61 10.1 10.1 0.061 13.4 4.0 2.1 2 1 0 2 2 2 0 N-terminal 7TM region of histidine kinase NAD_binding_10 PF13460.6 EOO00376.1 - 6.6e-13 48.9 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EOO00376.1 - 2.4e-10 40.4 0.0 3.3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EOO00376.1 - 4.1e-07 29.7 0.0 6.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EOO00376.1 - 1.6e-05 25.2 0.0 2.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EOO00376.1 - 0.0003 21.2 0.0 0.00051 20.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 EOO00376.1 - 0.0026 17.0 0.1 0.0041 16.3 0.1 1.3 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EOO00376.1 - 0.0031 16.9 0.1 0.0043 16.5 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EOO00376.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.20 EOO00376.1 - 0.035 14.2 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RTC PF01137.21 EOO00376.1 - 0.042 13.0 0.0 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 RNA 3'-terminal phosphate cyclase KR PF08659.10 EOO00376.1 - 0.046 13.6 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 EOO00376.1 - 0.053 12.5 0.1 0.098 11.6 0.1 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KDGP_aldolase PF07071.11 EOO00376.1 - 0.069 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 KDGP aldolase Polysacc_synt_2 PF02719.15 EOO00376.1 - 0.1 11.7 0.3 0.18 10.9 0.3 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein TFIIS_M PF07500.14 EOO00377.1 - 2.5e-21 76.3 1.8 6.2e-21 75.0 1.8 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 EOO00377.1 - 3e-15 56.4 0.0 5e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 EOO00377.1 - 2.1e-10 40.3 8.1 4.3e-10 39.3 8.1 1.5 1 0 0 1 1 1 1 PHD-finger DUF4050 PF13259.6 EOO00377.1 - 0.003 17.9 6.0 0.003 17.9 6.0 2.5 3 1 0 3 3 3 1 Protein of unknown function (DUF4050) zf-CW PF07496.15 EOO00377.1 - 0.075 13.1 2.7 0.21 11.7 2.7 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger zf-UDP PF14569.6 EOO00377.1 - 0.093 12.9 1.2 0.22 11.6 1.2 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger PHD_2 PF13831.6 EOO00377.1 - 1.2 8.7 3.5 2.4 7.8 3.5 1.5 1 0 0 1 1 1 0 PHD-finger CDC45 PF02724.14 EOO00377.1 - 2.3 6.4 7.6 3.9 5.7 7.6 1.4 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 EOO00377.1 - 3.3 6.4 9.7 7.4 5.2 9.7 1.6 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CCDC106 PF15794.5 EOO00378.1 - 2.1 8.0 10.5 0.045 13.4 2.8 2.0 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 106 RNA_pol_3_Rpc31 PF11705.8 EOO00378.1 - 6 7.0 22.4 0.92 9.7 15.4 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 V_ATPase_I PF01496.19 EOO00378.1 - 7 4.4 4.9 10 3.9 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_M36 PF02128.15 EOO00379.1 - 6e-105 351.4 3.1 6.7e-105 351.3 3.1 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 EOO00379.1 - 0.0017 18.3 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain p450 PF00067.22 EOO00380.1 - 1.5e-23 83.3 0.0 1.8e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EOO00381.1 - 3.7e-20 72.2 28.5 3.7e-20 72.2 28.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily CENP-B_N PF04218.13 EOO00381.1 - 0.029 14.0 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF1435 PF07256.12 EOO00381.1 - 3.5 7.8 7.1 0.31 11.1 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1435) DUF3951 PF13131.6 EOO00381.1 - 4 7.7 6.5 0.69 10.2 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3951) ABC_tran PF00005.27 EOO00382.1 - 5.3e-21 75.6 0.0 7.5e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EOO00382.1 - 0.0014 18.1 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EOO00382.1 - 0.0031 16.4 0.1 0.0039 16.1 0.1 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA PF00004.29 EOO00382.1 - 0.079 13.4 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 EOO00382.1 - 0.091 13.0 1.0 1.3 9.3 1.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit HET PF06985.11 EOO00383.1 - 7.6e-30 104.2 7.0 2.2e-29 102.7 7.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Gag_p12 PF01141.18 EOO00384.1 - 0.0024 18.1 0.5 0.0036 17.6 0.5 1.3 1 0 0 1 1 1 1 Gag polyprotein, inner coat protein p12 Ald_Xan_dh_C2 PF02738.18 EOO00385.1 - 8.1e-200 664.9 0.2 1.2e-199 664.4 0.2 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EOO00385.1 - 1.4e-39 135.6 0.0 2.7e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 EOO00385.1 - 1.3e-30 105.5 0.0 6.5e-30 103.4 0.0 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 EOO00385.1 - 6.1e-30 103.8 0.0 1.3e-29 102.7 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 EOO00385.1 - 2e-26 91.8 0.0 5e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 EOO00385.1 - 2e-06 27.7 1.0 2.9e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Glyco_hydro81C PF17652.1 EOO00386.1 - 1.1e-75 255.2 2.6 1.7e-75 254.4 2.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Fascin PF06268.13 EOO00386.1 - 0.00028 21.1 0.2 0.0039 17.4 0.1 2.3 1 1 0 1 1 1 1 Fascin domain RicinB_lectin_2 PF14200.6 EOO00386.1 - 0.011 16.5 5.4 0.78 10.5 1.1 2.8 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like FRG1 PF06229.12 EOO00386.1 - 0.064 13.0 2.2 0.32 10.7 0.4 2.0 1 1 1 2 2 2 0 FRG1-like domain Vma12 PF11712.8 EOO00387.1 - 1e-44 152.0 0.0 1.3e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1772 PF08592.11 EOO00387.1 - 0.008 16.5 0.7 0.013 15.8 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Amino_oxidase PF01593.24 EOO00388.1 - 8.2e-37 127.6 0.0 1.1e-36 127.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EOO00388.1 - 4.8e-10 39.5 0.0 2e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EOO00388.1 - 0.0069 15.7 0.1 0.042 13.1 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EOO00388.1 - 0.014 14.2 0.3 0.025 13.3 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 EOO00388.1 - 0.15 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DIOX_N PF14226.6 EOO00389.1 - 2.7e-13 50.7 0.0 4.1e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EOO00389.1 - 6.5e-06 26.6 0.0 1.2e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BTB PF00651.31 EOO00390.1 - 6.1e-21 74.7 0.0 5e-06 26.7 0.0 3.6 3 0 0 3 3 3 3 BTB/POZ domain Pex14_N PF04695.13 EOO00391.1 - 5.7e-36 124.6 0.6 5.7e-36 124.6 0.6 2.3 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF16 PF01519.16 EOO00391.1 - 0.0023 18.4 1.9 0.58 10.7 0.1 2.5 1 1 0 2 2 2 2 Protein of unknown function DUF16 PI3K_P85_iSH2 PF16454.5 EOO00391.1 - 0.0026 17.4 0.0 0.17 11.4 0.0 2.5 2 1 0 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain RecX PF02631.16 EOO00391.1 - 0.0042 17.5 0.0 0.0098 16.3 0.0 1.6 1 0 0 1 1 1 1 RecX family Tsc35 PF15079.6 EOO00391.1 - 0.052 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Testis-specific protein 35 DASH_Duo1 PF08651.10 EOO00391.1 - 0.091 12.5 2.5 13 5.6 0.1 3.0 3 0 0 3 3 3 0 DASH complex subunit Duo1 Flavi_DEAD PF07652.14 EOO00391.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain DASH_Dam1 PF08653.10 EOO00391.1 - 0.29 11.0 1.8 3.4 7.5 0.1 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 Anillin_N PF16018.5 EOO00391.1 - 0.72 10.5 4.4 0.7 10.5 0.2 2.8 2 1 1 3 3 3 0 Anillin N-terminus DUF3337 PF11816.8 EOO00392.1 - 1.6e-51 174.6 0.0 4.5e-42 143.8 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.32 EOO00392.1 - 3.8e-23 81.3 8.3 0.00063 20.5 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EOO00392.1 - 0.0006 18.9 0.2 0.099 11.6 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EOO00392.1 - 0.0028 17.9 0.1 0.34 11.2 0.1 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EOO00392.1 - 0.026 13.2 3.5 0.046 12.4 0.1 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Mito_carr PF00153.27 EOO00393.1 - 4.7e-69 228.4 4.4 4.1e-25 87.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EOO00393.1 - 0.0042 16.3 6.1 1.2 8.2 0.2 3.9 3 2 1 4 4 4 3 Gammaproteobacterial serine protease PAPA-1 PF04795.12 EOO00394.1 - 1.1e-29 103.1 6.0 1.1e-29 103.1 6.0 3.5 4 0 0 4 4 4 1 PAPA-1-like conserved region UbiA PF01040.18 EOO00395.1 - 1.2e-38 132.9 11.7 1.4e-38 132.6 11.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family PSII PF00421.19 EOO00395.1 - 0.16 10.6 6.0 0.21 10.2 6.0 1.1 1 0 0 1 1 1 0 Photosystem II protein GET2 PF08690.10 EOO00396.1 - 3e-46 158.5 0.0 3.8e-46 158.2 0.0 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 S10_plectin PF03501.15 EOO00397.1 - 1.9e-40 136.9 0.0 2.3e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Rio2_N PF09202.11 EOO00397.1 - 0.21 11.8 0.2 0.35 11.1 0.1 1.5 2 0 0 2 2 2 0 Rio2, N-terminal COX6B PF02297.17 EOO00398.1 - 1.2e-17 63.9 4.4 1.4e-17 63.7 4.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 EOO00398.1 - 0.029 14.4 1.2 0.047 13.7 1.2 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 EOO00398.1 - 0.063 13.2 1.2 0.065 13.2 0.7 1.5 1 1 0 1 1 1 0 APOBEC-like C-terminal domain ketoacyl-synt PF00109.26 EOO00398.1 - 0.068 12.7 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain YjzC PF14168.6 EOO00398.1 - 0.21 12.0 0.9 19 5.7 0.0 2.4 1 1 1 2 2 2 0 YjzC-like protein Leu_zip PF15294.6 EOO00399.1 - 0.01 15.4 2.5 0.012 15.1 2.5 1.0 1 0 0 1 1 1 0 Leucine zipper Fzo_mitofusin PF04799.13 EOO00399.1 - 0.028 14.0 0.6 0.033 13.7 0.6 1.0 1 0 0 1 1 1 0 fzo-like conserved region Med12-LCEWAV PF12145.8 EOO00399.1 - 0.053 12.4 0.3 0.058 12.2 0.3 1.1 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain ADK PF00406.22 EOO00400.1 - 1.6e-58 197.1 0.0 2.1e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EOO00400.1 - 6.2e-23 81.7 0.3 1.3e-22 80.7 0.1 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 EOO00400.1 - 4.2e-17 61.8 0.0 1.2e-16 60.4 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EOO00400.1 - 9.1e-05 23.0 0.0 0.00016 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EOO00400.1 - 0.00025 21.2 0.0 0.00047 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DJ-1_PfpI PF01965.24 EOO00401.1 - 1.3e-10 41.4 0.0 1.9e-10 40.8 0.0 1.3 1 1 0 1 1 1 1 DJ-1/PfpI family Gon7 PF08738.10 EOO00402.1 - 9.8e-08 32.1 8.4 1.2e-07 31.7 5.7 1.9 1 1 1 2 2 2 1 Gon7 family Evr1_Alr PF04777.13 EOO00402.1 - 0.13 12.7 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Erv1 / Alr family Coprogen_oxidas PF01218.18 EOO00403.1 - 3.6e-144 478.9 0.1 4.5e-144 478.6 0.1 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase SWIM PF04434.17 EOO00403.1 - 0.45 10.2 3.2 9.9 5.9 0.0 2.4 2 0 0 2 2 2 0 SWIM zinc finger DUF5315 PF17242.2 EOO00404.1 - 1.6e-28 98.3 0.7 3.6e-28 97.2 0.7 1.6 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) IL32 PF15225.6 EOO00404.1 - 0.12 12.7 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Interleukin 32 Brix PF04427.18 EOO00405.1 - 5.5e-39 134.3 0.0 7.9e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain Glyco_transf_90 PF05686.12 EOO00406.1 - 0.018 14.0 0.2 0.021 13.8 0.2 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 90 Gp_dh_C PF02800.20 EOO00408.1 - 2.8e-71 238.2 0.0 4.4e-71 237.6 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EOO00408.1 - 2.3e-39 133.8 0.1 4.4e-39 132.9 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EOO00408.1 - 0.0087 16.2 0.1 0.02 15.0 0.1 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus MitMem_reg PF13012.6 EOO00409.1 - 2.6e-37 127.6 0.2 4.9e-37 126.8 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EOO00409.1 - 2.6e-32 111.3 0.2 5.5e-32 110.2 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 EOO00409.1 - 0.018 14.7 2.6 0.028 14.1 2.6 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain SRA1 PF07304.11 EOO00411.1 - 9e-09 35.3 0.0 1.1e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 EOO00411.1 - 0.00035 20.7 0.2 0.0011 19.0 0.2 1.8 1 1 0 1 1 1 1 Prp18 domain C2 PF00168.30 EOO00412.1 - 3.1e-28 98.1 0.0 6.9e-16 58.4 0.0 2.7 2 0 0 2 2 2 2 C2 domain BTB PF00651.31 EOO00413.1 - 0.005 17.1 0.0 0.0072 16.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4632 PF15451.6 EOO00414.1 - 3.6 7.7 5.6 5 7.3 0.4 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4632) PTH2 PF01981.16 EOO00415.1 - 5.8e-46 155.6 0.3 7.4e-46 155.2 0.3 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Hom_end PF05204.14 EOO00415.1 - 0.098 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Homing endonuclease BING4CT PF08149.11 EOO00416.1 - 8.2e-41 137.7 0.0 4e-36 122.7 0.0 3.5 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 EOO00416.1 - 2.4e-06 27.8 0.7 6.8 7.1 0.0 5.9 3 1 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EOO00416.1 - 1.3e-05 25.9 0.0 0.032 15.1 0.0 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EOO00416.1 - 0.00033 19.8 0.0 0.0011 18.2 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region TauD PF02668.16 EOO00417.1 - 7.8e-55 186.5 0.5 9.1e-55 186.3 0.5 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Epimerase PF01370.21 EOO00418.1 - 3.3e-08 33.3 0.3 4.1e-07 29.7 0.3 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EOO00418.1 - 0.02 14.0 0.1 0.96 8.5 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Arb2 PF09757.9 EOO00419.1 - 5.9e-105 350.1 0.2 7.7e-105 349.7 0.2 1.1 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 EOO00419.1 - 8.5e-81 271.8 0.0 1.2e-80 271.3 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Benyvirus_P25 PF05744.11 EOO00419.1 - 0.025 13.9 0.1 0.053 12.8 0.1 1.5 1 0 0 1 1 1 0 Benyvirus P25/P26 protein Peptidase_M61 PF05299.12 EOO00419.1 - 0.049 14.0 0.0 0.097 13.1 0.0 1.5 1 0 0 1 1 1 0 M61 glycyl aminopeptidase JmjC PF02373.22 EOO00420.1 - 4.9e-10 39.9 0.1 1.8e-09 38.1 0.1 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 EOO00420.1 - 3.1e-09 36.9 9.1 3.1e-09 36.9 9.1 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 EOO00420.1 - 0.013 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Cupin domain HOOK PF05622.12 EOO00421.1 - 5.2e-07 28.2 100.1 2.2e-05 22.9 0.0 3.8 2 1 0 3 3 3 2 HOOK protein UPF0242 PF06785.11 EOO00421.1 - 0.0051 17.0 3.4 0.0051 17.0 3.4 6.1 3 2 2 5 5 5 1 Uncharacterised protein family (UPF0242) N-terminus MSV199 PF10553.9 EOO00421.1 - 0.31 11.3 4.0 0.34 11.2 0.7 2.8 1 1 1 2 2 2 0 MSV199 domain Mito_carr PF00153.27 EOO00422.1 - 6.8e-27 93.2 4.3 3.2e-17 62.2 0.1 2.3 2 1 0 2 2 2 2 Mitochondrial carrier protein cobW PF02492.19 EOO00423.1 - 8.4e-35 119.9 0.0 1.2e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EOO00423.1 - 6.3e-05 22.1 0.8 0.00085 18.4 0.8 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EOO00423.1 - 0.0029 17.7 0.0 0.0076 16.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EOO00423.1 - 0.0034 17.9 0.0 0.0046 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EOO00423.1 - 0.075 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 EOO00423.1 - 0.076 13.1 0.0 0.11 12.5 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 EOO00423.1 - 0.079 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 EOO00423.1 - 0.15 12.4 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Epimerase PF01370.21 EOO00424.1 - 1.2e-11 44.5 0.1 7.4e-11 42.0 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EOO00424.1 - 7.9e-09 34.9 0.0 1.6e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EOO00424.1 - 3.5e-08 33.6 0.1 7.2e-08 32.5 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EOO00424.1 - 9.1e-06 25.3 0.0 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EOO00424.1 - 1.2e-05 25.0 0.1 0.0011 18.6 0.1 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_4 PF07993.12 EOO00424.1 - 0.00018 20.7 0.0 0.0021 17.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein ADH_N PF08240.12 EOO00425.1 - 1.4e-35 121.5 0.8 5.3e-35 119.6 0.8 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EOO00425.1 - 4.4e-16 59.0 0.0 9.7e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EOO00425.1 - 2.7e-10 40.1 0.0 4.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EOO00425.1 - 7.4e-09 36.8 0.0 1.4e-08 35.9 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 EOO00425.1 - 0.002 17.4 0.4 0.0038 16.5 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 EOO00425.1 - 0.0023 18.2 0.0 0.0036 17.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 EOO00425.1 - 0.014 15.9 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ADH_N_2 PF16884.5 EOO00425.1 - 0.028 14.3 0.3 0.11 12.4 0.3 1.8 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase NAD_binding_8 PF13450.6 EOO00425.1 - 0.087 13.1 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF2318 PF10080.9 EOO00425.1 - 0.19 11.8 1.1 17 5.6 0.1 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) Staph_opine_DH PF10100.9 EOO00425.1 - 0.22 10.1 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Staphylopine dehydrogenase RRM_1 PF00076.22 EOO00426.1 - 6e-19 67.6 0.0 8.2e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EOO00426.1 - 0.00014 21.9 0.0 0.0002 21.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 EOO00426.1 - 0.022 14.9 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 RRM_5 PF13893.6 EOO00426.1 - 0.023 14.3 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fibin PF15819.5 EOO00426.1 - 0.08 12.7 0.0 0.17 11.6 0.0 1.5 1 1 0 1 1 1 0 Fin bud initiation factor homologue SET_assoc PF11767.8 EOO00426.1 - 0.097 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.6 EOO00426.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EOO00426.1 - 0.16 12.0 0.0 0.43 10.7 0.0 1.7 1 1 0 1 1 1 0 RNA binding motif RRM_occluded PF16842.5 EOO00426.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RIBIOP_C PF04950.12 EOO00427.1 - 2.7e-110 368.4 0.0 4.3e-110 367.7 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EOO00427.1 - 4.4e-18 65.2 0.0 1.1e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Ribosom_S12_S23 PF00164.25 EOO00428.1 - 3.8e-51 171.5 0.6 4.7e-51 171.2 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Sec16_C PF12931.7 EOO00429.1 - 1.7e-10 41.1 0.3 9e-10 38.7 0.3 2.0 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 EOO00429.1 - 2.8e-09 37.5 0.1 0.0081 17.0 0.0 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO00429.1 - 0.0018 18.5 0.0 1.3 9.3 0.0 3.5 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Papilin_u7 PF16626.5 EOO00430.1 - 0.0082 16.7 1.4 0.016 15.8 1.4 1.4 1 0 0 1 1 1 1 Linking region between Kunitz_BPTI and I-set on papilin Atg8 PF02991.16 EOO00431.1 - 3.1e-51 171.9 0.2 3.6e-51 171.7 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EOO00431.1 - 3.4e-06 27.4 0.0 4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF4050 PF13259.6 EOO00432.1 - 1.8e-36 126.2 3.6 3.5e-36 125.3 0.1 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF4050) SART-1 PF03343.13 EOO00434.1 - 6.3e-184 613.1 55.5 7.3e-184 612.8 55.5 1.0 1 0 0 1 1 1 1 SART-1 family Arg_tRNA_synt_N PF03485.16 EOO00434.1 - 0.048 14.2 0.1 0.19 12.3 0.1 2.0 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain HLH PF00010.26 EOO00435.1 - 4.3e-07 29.8 0.0 2e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Tom5 PF10642.9 EOO00435.1 - 0.68 10.0 4.1 1.2 9.2 0.2 3.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Presenilin PF01080.17 EOO00435.1 - 6.3 5.5 7.5 11 4.7 7.5 1.3 1 0 0 1 1 1 0 Presenilin Sde2_N_Ubi PF13019.6 EOO00436.1 - 1.6e-52 177.6 2.7 2.9e-52 176.8 2.7 1.4 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain LIM_bind PF01803.16 EOO00437.1 - 7.6e-74 248.3 0.0 7.6e-74 248.3 0.0 1.7 2 0 0 2 2 2 1 LIM-domain binding protein DUF3712 PF12505.8 EOO00439.1 - 6.4e-12 45.8 0.4 9.9e-11 42.0 0.1 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3712) Ras PF00071.22 EOO00440.1 - 2.7e-63 212.4 0.2 3.1e-63 212.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EOO00440.1 - 2.7e-35 121.2 0.2 3.9e-35 120.7 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EOO00440.1 - 4.6e-13 49.0 0.1 5.9e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EOO00440.1 - 7.9e-08 32.4 0.1 1.2e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EOO00440.1 - 0.00034 20.2 0.1 0.0017 17.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EOO00440.1 - 0.00043 19.7 0.1 0.00063 19.2 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EOO00440.1 - 0.00055 19.9 0.9 0.017 15.0 0.1 2.2 1 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EOO00440.1 - 0.0029 17.9 0.0 0.019 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 EOO00440.1 - 0.015 14.8 0.0 0.025 14.0 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EOO00440.1 - 0.017 15.1 0.1 0.046 13.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EOO00440.1 - 0.018 15.4 0.1 0.029 14.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EOO00440.1 - 0.022 15.3 0.1 0.03 14.8 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EOO00440.1 - 0.029 14.1 0.1 0.063 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EOO00440.1 - 0.033 13.6 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 EOO00440.1 - 0.093 12.5 0.5 0.14 12.0 0.5 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SpoIIID PF12116.8 EOO00440.1 - 0.098 12.8 0.1 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D FeoB_N PF02421.18 EOO00440.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 EOO00440.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region EF-hand_1 PF00036.32 EOO00441.1 - 3.1e-21 73.3 4.0 7.1e-06 25.2 0.0 3.1 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 EOO00441.1 - 2.2e-19 68.0 6.3 2e-06 27.0 0.6 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EOO00441.1 - 2.8e-19 69.3 4.2 6.6e-13 48.9 0.9 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EOO00441.1 - 2.7e-17 61.1 4.0 1.9e-05 24.2 0.1 3.1 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 EOO00441.1 - 5.1e-16 58.3 5.2 4.7e-05 23.2 0.0 3.1 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EOO00441.1 - 6.2e-06 26.5 0.0 0.0001 22.6 0.0 1.9 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EOO00441.1 - 0.0013 18.6 1.1 0.5 10.3 0.0 2.6 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 EOO00441.1 - 0.0015 18.4 0.6 1.7 8.6 0.0 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand CBM_20 PF00686.19 EOO00442.1 - 1.8e-31 107.9 0.2 2.2e-31 107.6 0.2 1.1 1 0 0 1 1 1 1 Starch binding domain Fn3-like PF14310.6 EOO00442.1 - 0.028 14.5 0.0 1.1 9.4 0.0 2.4 3 0 0 3 3 3 0 Fibronectin type III-like domain Peptidase_M6 PF05547.11 EOO00442.1 - 0.17 10.2 0.0 0.2 9.9 0.0 1.0 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 SPX PF03105.19 EOO00443.1 - 4.9e-35 122.2 24.6 2.1e-16 60.9 3.0 5.0 3 1 2 5 5 5 3 SPX domain Vps39_1 PF10366.9 EOO00443.1 - 2.3e-34 117.9 0.1 3.1e-32 111.1 0.0 3.3 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Na_sulph_symp PF00939.19 EOO00443.1 - 1.6e-28 100.0 43.7 1e-19 71.0 25.7 2.2 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EOO00443.1 - 9.1e-27 94.0 70.4 1.6e-22 80.1 44.5 2.8 2 1 1 3 3 3 2 Citrate transporter CNH PF00780.22 EOO00443.1 - 0.00032 20.4 0.0 0.00059 19.5 0.0 1.3 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 EOO00443.1 - 0.001 18.9 4.1 0.0018 18.1 0.3 3.0 3 0 0 3 3 3 1 Region in Clathrin and VPS HbrB PF08539.11 EOO00444.1 - 1.2e-55 188.1 0.4 3.2e-55 186.7 0.0 2.0 2 0 0 2 2 2 1 HbrB-like SUIM_assoc PF16619.5 EOO00444.1 - 2.7 8.1 11.7 14 5.9 11.7 2.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 V-SNARE_C PF12352.8 EOO00446.1 - 2.8e-15 56.3 1.2 6e-15 55.3 0.3 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EOO00446.1 - 0.00031 20.6 0.0 0.00073 19.4 0.0 1.6 1 0 0 1 1 1 1 Sec20 Sigma70_r4 PF04545.16 EOO00446.1 - 0.09 12.3 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 KxDL PF10241.9 EOO00446.1 - 0.16 12.3 2.8 6.9 7.0 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein MFS_1 PF07690.16 EOO00447.1 - 3.1e-52 177.6 39.6 7.2e-51 173.2 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO00447.1 - 7.7e-12 44.8 5.5 7.7e-12 44.8 5.5 2.5 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EOO00447.1 - 2.5e-06 26.2 6.8 3.8e-06 25.6 6.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EOO00447.1 - 0.0005 18.5 4.8 0.02 13.2 0.4 3.3 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Ctr PF04145.15 EOO00447.1 - 0.0095 16.6 0.4 6.3 7.4 0.0 3.4 4 0 0 4 4 4 1 Ctr copper transporter family EcsB PF05975.12 EOO00447.1 - 0.016 14.1 0.2 0.016 14.1 0.2 2.2 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB MFS_3 PF05977.13 EOO00447.1 - 1.8 6.8 17.3 0.01 14.3 7.2 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector Asp PF00026.23 EOO00448.1 - 8.6e-60 202.8 0.8 1e-59 202.5 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EOO00448.1 - 1.2e-09 38.6 0.4 1.8e-07 31.6 0.4 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EOO00448.1 - 6e-06 26.1 0.0 0.074 12.8 0.0 2.6 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EOO00448.1 - 0.0061 17.2 2.1 0.5 11.0 0.2 3.6 3 1 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 EOO00448.1 - 0.15 12.6 0.2 8.2 7.1 0.0 3.1 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease TPK_B1_binding PF04265.14 EOO00449.1 - 1.7e-25 88.5 0.2 2.5e-25 88.0 0.2 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.16 EOO00449.1 - 1.4e-20 73.5 0.1 2.1e-20 73.0 0.1 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain DUF5353 PF17304.2 EOO00450.1 - 4.2e-22 77.6 2.3 5.8e-22 77.2 2.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5353) DUF5486 PF17588.2 EOO00450.1 - 0.12 12.3 0.8 0.21 11.5 0.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5486) GFA PF04828.14 EOO00451.1 - 1.6e-14 54.0 6.6 8e-07 29.3 1.4 2.8 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme CHCH PF06747.13 EOO00452.1 - 5.1e-06 26.5 4.6 8.5e-06 25.8 4.6 1.4 1 0 0 1 1 1 1 CHCH domain Pro-kuma_activ PF09286.11 EOO00453.1 - 9.5e-40 136.2 0.1 3e-39 134.6 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain WD40 PF00400.32 EOO00454.1 - 4.5e-16 58.9 16.6 1.3e-06 29.0 1.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO00454.1 - 8e-12 45.3 1.6 0.0027 18.0 0.3 4.3 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EOO00454.1 - 0.00011 21.0 0.4 0.016 13.9 0.1 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 EOO00454.1 - 0.00032 20.6 0.1 0.073 12.9 0.0 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EOO00454.1 - 0.00055 18.6 0.2 0.0025 16.4 0.2 1.7 1 1 0 1 1 1 1 Cytochrome D1 heme domain Hira PF07569.11 EOO00454.1 - 0.0022 17.7 0.7 0.077 12.7 0.0 2.3 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40_like PF17005.5 EOO00454.1 - 0.0084 15.5 0.0 0.084 12.2 0.0 2.2 1 1 1 2 2 2 1 WD40-like domain PALB2_WD40 PF16756.5 EOO00454.1 - 0.045 12.7 4.0 0.056 12.4 0.6 2.3 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain CobU PF02283.16 EOO00455.1 - 0.19 11.3 2.6 0.38 10.3 2.6 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase adh_short PF00106.25 EOO00456.1 - 4.2e-35 121.0 0.3 5e-35 120.7 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO00456.1 - 4.9e-26 91.7 0.1 6e-26 91.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO00456.1 - 4.3e-11 43.1 0.7 5.6e-11 42.7 0.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO00456.1 - 2.9e-06 26.9 0.1 3.3e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EOO00456.1 - 0.015 14.5 0.1 0.017 14.3 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 EOO00456.1 - 0.088 12.1 0.1 1.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain YaiA PF16362.5 EOO00456.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 YaiA protein Q_salvage PF10343.9 EOO00457.1 - 4.3e-129 430.1 0.1 5.2e-129 429.8 0.1 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family EHN PF06441.12 EOO00458.1 - 1.4e-29 102.6 0.1 2.1e-29 102.0 0.1 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EOO00458.1 - 6.6e-12 45.6 0.0 8.7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EOO00458.1 - 0.0002 22.0 0.0 0.0026 18.4 0.0 2.1 1 1 0 2 2 2 1 Alpha/beta hydrolase family DNA_pol_delta_4 PF04081.13 EOO00459.1 - 3.3e-44 150.4 3.2 5.9e-44 149.6 3.2 1.5 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 ThiF PF00899.21 EOO00460.1 - 6.6e-75 251.6 0.1 1.4e-74 250.6 0.0 1.5 2 0 0 2 2 2 1 ThiF family UAE_UbL PF14732.6 EOO00460.1 - 4.4e-23 81.7 1.4 4.4e-23 81.7 1.4 2.0 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 EOO00460.1 - 6.5e-06 26.3 7.3 1e-05 25.6 0.3 2.8 2 1 1 3 3 3 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EOO00460.1 - 0.00054 20.4 0.0 0.0018 18.7 0.0 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EOO00460.1 - 0.01 15.9 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EOO00460.1 - 0.29 11.4 2.2 1.1 9.5 0.7 2.5 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Guanylate_kin PF00625.21 EOO00461.1 - 6.2e-54 182.4 0.1 7.3e-54 182.2 0.1 1.0 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 EOO00461.1 - 0.0011 19.1 0.0 0.0038 17.3 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EOO00461.1 - 0.018 15.2 0.1 0.087 13.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EOO00462.1 - 1.8e-109 365.4 0.5 2.2e-109 365.1 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EOO00462.1 - 1.1e-07 31.9 0.0 2.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EOO00462.1 - 9.9e-06 25.0 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EOO00462.1 - 3.6e-05 23.7 0.1 0.00049 20.0 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EOO00462.1 - 6e-05 22.7 0.8 0.029 13.9 0.1 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EOO00462.1 - 0.0011 19.0 0.3 1.3 9.0 0.1 2.5 1 1 1 2 2 2 2 Dynamin family AAA_22 PF13401.6 EOO00462.1 - 0.0049 17.2 0.1 0.013 15.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EOO00462.1 - 0.0082 15.7 0.0 0.051 13.1 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 EOO00462.1 - 0.0084 15.3 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EOO00462.1 - 0.0099 16.3 0.0 0.029 14.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 EOO00462.1 - 0.019 15.5 0.5 0.03 14.8 0.5 1.6 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 EOO00462.1 - 0.025 13.9 0.1 0.44 9.9 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 EOO00462.1 - 0.04 13.3 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 EOO00462.1 - 0.06 12.5 0.4 0.33 10.1 0.1 2.0 1 1 1 2 2 2 0 G-protein alpha subunit Roc PF08477.13 EOO00462.1 - 0.079 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EOO00462.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MFS_1 PF07690.16 EOO00463.1 - 1.9e-14 53.4 32.8 2.7e-14 52.9 32.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EOO00463.1 - 2.6e-08 33.8 7.7 2.6e-08 33.8 7.7 2.3 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 EXS PF03124.14 EOO00463.1 - 0.0011 18.4 3.1 0.0011 18.4 3.1 1.9 2 0 0 2 2 2 1 EXS family LapA_dom PF06305.11 EOO00463.1 - 1.2 9.0 11.6 1.3 8.9 0.0 4.4 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain SSF PF00474.17 EOO00464.1 - 1.4e-06 27.4 4.7 1.4e-06 27.4 4.7 1.9 2 0 0 2 2 2 1 Sodium:solute symporter family DUF2207 PF09972.9 EOO00464.1 - 0.045 12.5 0.0 0.045 12.5 0.0 2.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2613 PF11021.8 EOO00464.1 - 7.4 6.8 6.0 2.2 8.4 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) GMC_oxred_C PF05199.13 EOO00465.1 - 2.1e-17 64.0 0.0 5.5e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EOO00465.1 - 1.8e-06 27.5 0.0 4.9e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase PAP2 PF01569.21 EOO00466.1 - 4.4e-19 68.6 1.8 1e-18 67.4 1.8 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EOO00466.1 - 0.00058 19.6 2.6 0.0015 18.3 2.6 1.8 1 0 0 1 1 1 1 PAP2 superfamily CHD5 PF04420.14 EOO00466.1 - 0.21 11.4 0.6 0.37 10.7 0.6 1.3 1 0 0 1 1 1 0 CHD5-like protein Autophagy_N PF03986.13 EOO00467.1 - 5.4e-43 146.2 0.0 1.5e-42 144.8 0.0 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 EOO00467.1 - 5.7e-16 58.9 0.1 1e-15 58.0 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 EOO00467.1 - 1.3e-15 56.6 0.5 2.3e-15 55.7 0.5 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Acyltransferase PF01553.21 EOO00468.1 - 8.1e-10 38.4 0.0 1.2e-07 31.4 0.0 2.2 1 1 1 2 2 2 2 Acyltransferase Acyltransf_C PF16076.5 EOO00468.1 - 2.7e-06 27.4 0.1 5.9e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus DUF1581 PF07619.11 EOO00468.1 - 0.021 14.9 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) LAL_C2 PF18603.1 EOO00468.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 FSA_C PF10479.9 EOO00469.1 - 1.4 6.9 8.0 1.9 6.5 8.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RRM_1 PF00076.22 EOO00470.1 - 1.8e-30 104.6 0.1 1.1e-12 47.5 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EOO00470.1 - 3.2e-08 33.3 0.0 0.021 14.7 0.0 3.5 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EOO00470.1 - 0.016 15.2 0.0 0.8 9.7 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF3915 PF13054.6 EOO00470.1 - 4.4 7.3 5.6 9.1 6.3 5.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) CDC45 PF02724.14 EOO00470.1 - 8.5 4.5 5.4 11 4.1 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SF3b1 PF08920.10 EOO00471.1 - 3.5e-26 92.0 3.5 3.5e-26 92.0 3.5 2.9 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 EOO00471.1 - 3.3e-12 46.6 2.8 0.015 15.8 0.0 7.3 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 EOO00471.1 - 1.4e-10 41.4 9.0 0.6 10.5 0.0 7.8 5 3 3 9 9 9 3 HEAT repeats HEAT PF02985.22 EOO00471.1 - 1e-09 37.8 8.4 0.76 10.2 0.1 9.3 9 0 0 9 9 9 3 HEAT repeat Vac14_Fab1_bd PF12755.7 EOO00471.1 - 1.1e-05 25.9 0.3 1.1 9.9 0.0 5.4 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EOO00471.1 - 9.4e-05 22.4 2.0 0.048 13.6 0.1 4.9 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) NUC173 PF08161.12 EOO00471.1 - 0.00013 21.7 0.5 0.95 9.1 0.0 4.4 4 1 0 5 5 5 2 NUC173 domain Adaptin_N PF01602.20 EOO00471.1 - 0.00021 20.0 0.2 0.1 11.1 0.0 3.2 2 2 0 3 3 3 2 Adaptin N terminal region UNC45-central PF11701.8 EOO00471.1 - 0.0011 18.9 0.0 0.0038 17.2 0.0 1.8 2 0 0 2 2 1 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 EOO00471.1 - 0.0089 15.6 0.1 1.8 8.0 0.0 3.6 4 0 0 4 4 4 1 CLASP N terminal DRIM PF07539.12 EOO00471.1 - 0.016 13.6 0.1 9.5 4.4 0.0 3.7 2 1 1 3 3 3 0 Down-regulated in metastasis MMS19_C PF12460.8 EOO00471.1 - 0.14 11.2 0.0 8.8 5.3 0.0 3.3 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal LSM PF01423.22 EOO00472.1 - 6.6e-17 61.0 0.0 1.1e-16 60.3 0.0 1.4 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EOO00472.1 - 0.011 15.9 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Hfq PF17209.3 EOO00472.1 - 0.023 14.3 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Ribosomal_S13_N PF08069.12 EOO00473.1 - 7.2e-31 106.0 0.1 1.2e-30 105.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EOO00473.1 - 1.3e-15 57.4 0.2 1.9e-15 56.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 EOO00473.1 - 0.0094 15.9 0.1 0.024 14.6 0.0 1.7 2 0 0 2 2 2 1 'Paired box' domain VRR_NUC PF08774.11 EOO00474.1 - 4.2e-23 81.5 0.0 1.1e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain bZIP_1 PF00170.21 EOO00475.1 - 3.6e-05 23.8 10.8 5.9e-05 23.1 10.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 EOO00475.1 - 0.13 12.6 1.0 0.24 11.7 1.0 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF5082 PF16888.5 EOO00475.1 - 0.23 11.8 2.5 0.38 11.0 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) bZIP_2 PF07716.15 EOO00475.1 - 2.4 8.3 13.4 18 5.5 12.7 2.1 1 1 0 1 1 1 0 Basic region leucine zipper Dpy-30 PF05186.13 EOO00476.1 - 3.8e-15 55.3 0.0 5.1e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif CBFB_NFYA PF02045.15 EOO00477.1 - 3.1e-28 98.2 4.6 6.8e-28 97.1 4.6 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 EOO00477.1 - 0.18 10.9 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Hus1-like protein Pkinase PF00069.25 EOO00478.1 - 2.2e-45 155.1 0.0 1.1e-39 136.4 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EOO00478.1 - 3e-21 75.9 0.0 5.1e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Response_reg PF00072.24 EOO00478.1 - 7.8e-10 38.9 0.0 1.9e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 EOO00478.1 - 7.1e-08 32.1 0.0 4.8e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EOO00478.1 - 9.9e-05 22.4 1.2 0.0025 17.8 0.1 3.0 3 1 0 4 4 4 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EOO00478.1 - 0.0073 15.3 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EOO00478.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.7 EOO00478.1 - 0.034 14.4 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 PAS domain Seadorna_VP7 PF07387.11 EOO00478.1 - 0.088 11.8 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PAS PF00989.25 EOO00478.1 - 0.14 12.2 0.1 0.61 10.1 0.0 2.1 1 1 1 2 2 2 0 PAS fold DRMBL PF07522.14 EOO00479.1 - 2e-31 108.4 0.0 4.4e-31 107.3 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EOO00479.1 - 2.1e-06 27.4 0.0 4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Zn-ribbon_8 PF09723.10 EOO00479.1 - 0.053 13.6 0.1 0.19 11.8 0.1 2.0 1 0 0 1 1 1 0 Zinc ribbon domain Cullin PF00888.22 EOO00480.1 - 1.9e-203 677.5 1.8 2.5e-203 677.1 1.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EOO00480.1 - 1.7e-25 88.8 0.6 5.2e-25 87.3 0.6 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain MarR_2 PF12802.7 EOO00480.1 - 0.085 12.8 0.0 5 7.1 0.0 2.9 2 0 0 2 2 2 0 MarR family Rrf2 PF02082.20 EOO00480.1 - 0.087 13.2 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator CwfJ_C_1 PF04677.15 EOO00481.1 - 4.7e-19 68.4 0.0 7.4e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EOO00481.1 - 3.1e-14 53.6 0.4 6.4e-14 52.6 0.4 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.12 EOO00483.1 - 1.5e-199 664.4 4.4 1.5e-199 664.4 4.4 3.9 4 0 0 4 4 4 1 Down-regulated in metastasis HEAT_2 PF13646.6 EOO00483.1 - 0.0023 18.3 5.7 6.2 7.3 0.1 6.3 6 0 0 6 6 6 2 HEAT repeats Vac14_Fab1_bd PF12755.7 EOO00483.1 - 0.039 14.6 3.6 0.9 10.2 0.0 4.8 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EOO00483.1 - 0.049 13.9 17.2 4.7 7.7 0.0 8.5 11 0 0 11 11 11 0 HEAT repeat Sulfatase PF00884.23 EOO00484.1 - 5.4e-55 187.0 0.0 6.8e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 EOO00484.1 - 1e-28 98.9 3.6 7.4e-28 96.1 1.0 2.5 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 EOO00484.1 - 2.9e-09 37.0 0.0 0.0018 17.9 0.0 2.4 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EOO00484.1 - 0.0016 17.1 0.0 0.0024 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) MFS_1 PF07690.16 EOO00485.1 - 1e-11 44.4 11.2 1.4e-11 44.0 11.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF126 PF01989.16 EOO00485.1 - 0.097 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Aconitase X swivel domain Chromo PF00385.24 EOO00486.1 - 9.1e-17 60.7 0.8 1.4e-16 60.1 0.8 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 EOO00486.1 - 0.024 14.7 0.2 0.044 13.9 0.2 1.4 1 0 0 1 1 1 0 Chromo shadow domain SOG2 PF10428.9 EOO00486.1 - 3.3 6.8 6.4 3.5 6.7 6.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DAHP_synth_2 PF01474.16 EOO00487.1 - 1.2e-202 673.2 0.0 1.4e-202 673.0 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family RNase_P_p30 PF01876.16 EOO00488.1 - 1.7e-56 191.1 0.0 2.2e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Rif1_N PF12231.8 EOO00490.1 - 7.3e-99 331.3 0.5 8.2e-99 331.1 0.5 1.0 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal DUF3050 PF11251.8 EOO00490.1 - 0.0015 18.2 0.1 0.0086 15.7 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3050) DNA_pol_phi PF04931.13 EOO00490.1 - 0.038 12.1 0.7 1.4 6.9 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase phi AcylCoA_dehyd_C PF12186.8 EOO00490.1 - 0.039 14.1 0.1 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal MMS19_N PF14500.6 EOO00490.1 - 0.085 12.4 0.2 0.2 11.2 0.1 1.7 1 1 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Epimerase PF01370.21 EOO00491.1 - 7.5e-10 38.7 0.0 0.00025 20.6 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EOO00491.1 - 6.8e-08 32.6 0.0 1.1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EOO00491.1 - 3.4e-07 30.1 0.0 5.4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 EOO00491.1 - 0.0098 16.3 0.0 0.021 15.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EOO00491.1 - 0.013 14.9 0.0 0.28 10.5 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EOO00491.1 - 0.014 14.4 0.0 0.56 9.2 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EOO00491.1 - 0.14 11.3 0.0 0.4 9.8 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein PQ-loop PF04193.14 EOO00492.1 - 1.4e-25 88.8 7.7 5.8e-14 51.6 2.8 2.5 2 0 0 2 2 2 2 PQ loop repeat WLM PF08325.10 EOO00493.1 - 8.7e-61 205.3 0.0 1.4e-60 204.7 0.0 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 EOO00493.1 - 7.4e-08 31.6 16.0 9.2e-07 28.1 1.7 3.3 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others zinc_ribbon_15 PF17032.5 EOO00493.1 - 0.0028 18.3 1.3 0.006 17.3 1.3 1.5 1 1 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 EOO00493.1 - 0.011 15.8 6.7 0.16 12.0 7.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 EOO00493.1 - 0.013 14.9 3.1 0.1 12.0 0.9 2.6 2 0 0 2 2 2 0 zinc-ribbon domain C1_2 PF03107.16 EOO00493.1 - 0.017 15.4 4.6 0.75 10.2 0.4 2.6 2 0 0 2 2 2 0 C1 domain DUF45 PF01863.17 EOO00493.1 - 0.33 11.0 0.9 0.74 9.8 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 zf-HIT PF04438.16 EOO00493.1 - 2.3 8.1 8.1 4.6 7.2 0.5 2.3 2 0 0 2 2 2 0 HIT zinc finger RNA_POL_M_15KD PF02150.16 EOO00493.1 - 7.4 6.5 8.6 22 5.0 0.7 2.7 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-Sec23_Sec24 PF04810.15 EOO00493.1 - 8.7 6.5 14.2 1.7 8.8 0.8 3.4 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger Asp PF00026.23 EOO00494.1 - 2.7e-74 250.4 6.1 3.4e-74 250.1 6.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EOO00494.1 - 3.3e-12 47.0 3.0 3e-09 37.4 3.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EOO00494.1 - 0.0003 21.4 2.7 0.03 15.0 0.5 3.8 3 1 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 EOO00494.1 - 0.026 15.1 1.9 0.66 10.6 0.3 3.6 3 1 1 4 4 4 0 gag-polyprotein putative aspartyl protease Cupin_2 PF07883.11 EOO00495.1 - 0.00012 21.8 0.0 0.00053 19.6 0.0 2.1 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EOO00495.1 - 0.082 12.5 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Cupin Med8 PF10232.9 EOO00496.1 - 8.7e-38 130.2 0.5 1.1e-37 129.9 0.5 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 SPT6_acidic PF14632.6 EOO00496.1 - 0.82 10.3 17.2 1.2 9.8 5.9 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Tub_N PF16322.5 EOO00496.1 - 2.6 8.4 7.6 8.3 6.8 7.8 1.4 1 1 0 1 1 1 0 Tubby N-terminal DUF4611 PF15387.6 EOO00496.1 - 5.1 7.4 13.1 2.5 8.4 2.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nop14 PF04147.12 EOO00496.1 - 5.5 5.1 13.1 7.9 4.6 13.1 1.1 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.18 EOO00496.1 - 6.5 6.6 7.2 5.1 6.9 1.6 2.1 2 0 0 2 2 2 0 Myc amino-terminal region S-antigen PF05756.11 EOO00496.1 - 8.9 6.8 7.0 12 6.3 0.3 2.3 2 0 0 2 2 2 0 S-antigen protein CENP-B_dimeris PF09026.10 EOO00496.1 - 9.1 6.7 14.4 4.6 7.7 3.7 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HisKA PF00512.25 EOO00497.1 - 3.6e-21 75.0 0.4 1.1e-20 73.4 0.1 2.1 2 0 0 2 2 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 EOO00497.1 - 9.2e-19 67.7 0.2 2.5e-18 66.3 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 EOO00497.1 - 8.1e-18 64.5 0.1 6.2e-17 61.7 0.3 2.3 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EOO00497.1 - 1.2e-11 44.8 1.3 7.6e-07 29.4 0.0 4.2 3 2 0 3 3 3 2 PAS fold HATPase_c PF02518.26 EOO00497.1 - 6.3e-11 42.8 0.3 2.1e-10 41.1 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 EOO00497.1 - 2.3e-10 40.7 0.0 4.1e-06 27.0 0.0 3.9 3 1 0 3 3 3 2 PAS domain PAS PF00989.25 EOO00497.1 - 1.6e-09 37.8 0.0 3.8e-05 23.6 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 EOO00497.1 - 0.004 17.2 0.1 3.8 7.7 0.0 3.6 3 0 0 3 3 3 1 PAS domain GRIP PF01465.20 EOO00497.1 - 0.06 13.3 0.0 0.65 10.0 0.0 2.5 2 0 0 2 2 2 0 GRIP domain PMC2NT PF08066.12 EOO00497.1 - 0.09 13.5 3.7 13 6.6 0.1 3.6 3 1 1 4 4 4 0 PMC2NT (NUC016) domain LZ_Tnp_IS66 PF13007.7 EOO00497.1 - 5.3 7.9 8.9 0.86 10.4 2.9 2.7 3 0 0 3 3 3 0 Transposase C of IS166 homeodomain Snurportin1 PF11538.8 EOO00497.1 - 8 6.8 11.2 0.71 10.1 2.1 2.7 2 0 0 2 2 2 0 Snurportin1 COesterase PF00135.28 EOO00499.1 - 5.1e-08 32.2 0.0 6.1e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Aldose_epim PF01263.20 EOO00500.1 - 2.7e-41 141.8 0.0 3.5e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase SWIRM-assoc_2 PF16496.5 EOO00501.1 - 7.7e-05 21.7 0.1 7.7e-05 21.7 0.1 3.5 2 1 1 3 3 3 1 SWIRM-associated domain at the N-terminal DUF1749 PF08538.10 EOO00501.1 - 0.15 11.1 0.0 0.32 10.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) AT_hook PF02178.19 EOO00501.1 - 3.3 7.9 13.1 4.2 7.6 1.4 4.1 3 0 0 3 3 3 0 AT hook motif Ric8 PF10165.9 EOO00502.1 - 1.5e-118 396.8 1.7 1.7e-118 396.6 1.7 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn WAPL PF07814.13 EOO00502.1 - 0.0011 17.8 0.1 0.0085 14.9 0.0 2.0 1 1 1 2 2 2 1 Wings apart-like protein regulation of heterochromatin DUF4553 PF15090.6 EOO00503.1 - 3.2 6.6 9.8 4.4 6.2 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4553) T6SS_VasJ PF16989.5 EOO00504.1 - 0.12 11.8 1.3 0.32 10.4 1.3 1.7 1 1 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ DUF1295 PF06966.12 EOO00505.1 - 9.7e-56 188.9 0.2 1.2e-55 188.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EOO00505.1 - 7.2e-06 26.1 2.8 1.6e-05 24.9 0.1 2.7 2 1 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 EOO00505.1 - 1.2e-05 25.7 0.5 4.7e-05 23.7 0.0 2.3 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EOO00505.1 - 0.0066 16.8 0.9 0.038 14.4 0.1 2.7 3 1 0 3 3 3 1 Phospholipid methyltransferase DUF5079 PF16882.5 EOO00505.1 - 4.5 7.1 6.9 6 6.7 2.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5079) Rhodanese PF00581.20 EOO00506.1 - 6.4e-13 49.2 0.0 1.2e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain TPR_1 PF00515.28 EOO00507.1 - 3.3e-53 175.4 34.5 2.5e-08 33.4 0.0 10.7 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 EOO00507.1 - 1.1e-47 156.3 26.3 2.6e-07 30.2 0.0 10.6 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_8 PF13181.6 EOO00507.1 - 3.3e-41 136.0 23.7 3.5e-08 33.0 0.0 10.6 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.6 EOO00507.1 - 1.3e-28 97.3 20.7 0.00021 21.5 0.0 10.5 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_14 PF13428.6 EOO00507.1 - 4.9e-27 92.3 14.3 0.00011 22.7 0.0 9.2 4 2 5 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.6 EOO00507.1 - 5.5e-26 90.9 16.2 9.8e-07 29.3 0.4 6.8 3 3 4 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EOO00507.1 - 8.9e-25 86.1 34.4 3.6e-06 26.6 0.2 9.7 5 2 5 10 10 10 6 TPR repeat TPR_19 PF14559.6 EOO00507.1 - 2.9e-24 85.3 20.4 0.0004 20.8 0.1 7.1 5 1 2 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 EOO00507.1 - 7.2e-24 83.9 21.9 3.7e-05 23.9 0.8 7.3 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 EOO00507.1 - 1e-22 79.2 15.0 0.00053 20.5 0.0 9.4 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 EOO00507.1 - 6.6e-18 63.4 15.0 0.0098 15.9 0.1 9.4 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 EOO00507.1 - 5.9e-15 55.2 12.6 0.0011 19.1 0.1 6.9 1 1 8 9 9 9 7 Tetratricopeptide repeat ANAPC3 PF12895.7 EOO00507.1 - 2.7e-12 46.8 15.6 2.7e-08 33.9 1.8 3.9 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EOO00507.1 - 9.8e-12 44.7 10.3 0.0087 15.3 1.2 5.2 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_21 PF09976.9 EOO00507.1 - 3.2e-08 33.5 10.2 0.0017 18.1 0.0 4.8 4 2 0 4 4 4 2 Tetratricopeptide repeat-like domain BTAD PF03704.17 EOO00507.1 - 5.6e-05 23.6 5.5 0.35 11.3 0.1 3.6 3 0 0 3 3 3 1 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 EOO00507.1 - 0.0012 18.9 0.4 39 4.4 0.0 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.9 EOO00507.1 - 0.0066 16.2 4.1 1.5 8.5 0.0 3.3 1 1 2 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 EOO00507.1 - 0.017 14.9 24.2 7.1 6.6 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_20 PF14561.6 EOO00507.1 - 0.021 15.2 12.3 0.49 10.8 0.2 4.3 5 1 1 6 6 4 0 Tetratricopeptide repeat SNAP PF14938.6 EOO00507.1 - 0.9 8.9 16.7 7.4 5.9 1.7 4.5 1 1 3 4 4 4 0 Soluble NSF attachment protein, SNAP Chorismate_bind PF00425.18 EOO00508.1 - 4.2e-92 308.4 0.0 5.1e-90 301.5 0.0 2.1 2 0 0 2 2 2 2 chorismate binding enzyme Anth_synt_I_N PF04715.13 EOO00508.1 - 2.7e-28 99.0 0.1 1.4e-24 86.9 0.0 3.5 2 1 0 3 3 3 2 Anthranilate synthase component I, N terminal region DUF1751 PF08551.10 EOO00509.1 - 0.0054 17.3 0.3 0.0054 17.3 0.3 1.9 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) NuiA PF07924.11 EOO00510.1 - 0.011 16.1 0.0 0.21 12.0 0.0 2.1 1 1 1 2 2 2 0 Nuclease A inhibitor-like protein Phage_lambda_P PF06992.11 EOO00510.1 - 0.21 11.3 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Replication protein P Ribosomal_L3 PF00297.22 EOO00511.1 - 2.6e-179 595.9 11.0 3e-179 595.7 11.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 MFS_1 PF07690.16 EOO00512.1 - 2.2e-35 122.3 41.5 2.2e-35 122.3 41.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO00512.1 - 3.6e-10 39.3 16.4 3.6e-10 39.3 16.4 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter DnaJ PF00226.31 EOO00513.1 - 3.5e-23 81.5 0.8 7.1e-23 80.5 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain AA_permease PF00324.21 EOO00514.1 - 1.5e-123 412.9 38.4 1.8e-123 412.6 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EOO00514.1 - 3.8e-36 124.8 39.2 4.7e-36 124.5 39.2 1.0 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 EOO00516.1 - 4.1e-51 174.2 0.0 5e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Insulin_TMD PF17870.1 EOO00516.1 - 0.027 14.6 0.1 0.058 13.5 0.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment MFS_1 PF07690.16 EOO00517.1 - 7.7e-19 67.8 12.1 7.7e-19 67.8 12.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EOO00517.1 - 0.004 15.5 6.5 0.012 13.9 4.3 2.4 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF2434 PF10361.9 EOO00519.1 - 7.2e-139 461.8 9.0 1e-138 461.3 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) Transp_cyt_pur PF02133.15 EOO00521.1 - 1.9e-24 86.3 0.8 2.2e-24 86.1 0.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Epimerase PF01370.21 EOO00522.1 - 2.7e-13 50.0 0.1 5e-13 49.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO00522.1 - 3.3e-12 46.4 0.0 3.5e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EOO00522.1 - 6.9e-10 38.4 0.0 8.4e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EOO00522.1 - 2.7e-08 33.9 0.1 3.2e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EOO00522.1 - 6.7e-07 28.7 0.0 2.2e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 EOO00522.1 - 7.8e-07 28.9 0.1 1.2e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 EOO00522.1 - 3.7e-06 27.0 0.0 2.2e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EOO00522.1 - 0.004 16.3 0.2 0.008 15.3 0.1 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EOO00522.1 - 0.0041 16.6 0.2 0.0087 15.5 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 EOO00522.1 - 0.0058 16.9 0.0 0.0073 16.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF5481 PF17578.2 EOO00522.1 - 0.039 14.3 0.0 0.15 12.4 0.0 1.8 1 1 0 2 2 2 0 Family of unknown function (DUF5481) Vert_IL3-reg_TF PF06529.11 EOO00523.1 - 0.02 14.1 0.0 0.02 14.1 0.0 1.0 1 0 0 1 1 1 0 Vertebrate interleukin-3 regulated transcription factor DUF2205 PF10224.9 EOO00523.1 - 0.058 13.4 0.5 9 6.4 0.1 2.1 2 0 0 2 2 2 0 Short coiled-coil protein CMD PF02627.20 EOO00525.1 - 2.2e-18 66.1 0.1 4.5e-18 65.1 0.0 1.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family 5_nucleotid_C PF02872.18 EOO00526.1 - 7.4e-36 123.7 0.0 1.5e-35 122.7 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EOO00526.1 - 9.5e-10 39.3 1.8 1e-08 35.9 0.5 2.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Sulfotransfer_4 PF17784.1 EOO00527.1 - 3.4e-50 170.8 0.0 4e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EOO00527.1 - 0.0097 16.3 0.2 0.018 15.4 0.1 1.7 1 1 0 1 1 1 1 Sulfotransferase family Fasciclin PF02469.22 EOO00528.1 - 1.1e-34 119.4 1.3 9.7e-23 80.8 0.5 2.1 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_115 PF15979.5 EOO00529.1 - 2.3e-145 484.3 0.2 3.5e-145 483.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 EOO00529.1 - 3.5e-63 212.5 0.0 8.2e-63 211.3 0.0 1.7 2 0 0 2 2 2 1 Gylcosyl hydrolase family 115 C-terminal domain NTPase_P4 PF11602.8 EOO00529.1 - 0.079 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 Melibiase_2 PF16499.5 EOO00530.1 - 7.8e-51 172.9 0.3 1e-50 172.5 0.3 1.1 1 0 0 1 1 1 1 Alpha galactosidase A DUF905 PF06006.12 EOO00530.1 - 0.0035 17.3 0.2 0.05 13.6 0.0 2.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF905) ketoacyl-synt PF00109.26 EOO00531.1 - 2.7e-34 118.9 0.0 3.5e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EOO00531.1 - 4.4e-13 49.3 0.0 8.2e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain p450 PF00067.22 EOO00532.1 - 2.6e-28 99.0 0.0 3.8e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PepX_C PF08530.10 EOO00532.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain EIIBC-GUT_N PF03612.14 EOO00532.1 - 0.23 11.2 0.1 0.35 10.6 0.1 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Cwf_Cwc_15 PF04889.12 EOO00533.1 - 0.021 14.6 4.5 0.044 13.5 4.5 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.14 EOO00533.1 - 0.43 10.3 2.4 0.82 9.4 2.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 EOO00533.1 - 0.5 9.6 8.6 0.16 11.3 5.2 1.8 2 0 0 2 2 2 0 NOA36 protein PBP1_TM PF14812.6 EOO00533.1 - 3.6 8.0 10.7 1.2 9.5 5.2 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal COG5 PF10392.9 EOO00535.1 - 4.2e-40 137.0 0.2 1.1e-39 135.6 0.0 1.8 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Laminin_I PF06008.14 EOO00535.1 - 0.017 14.9 0.2 0.027 14.2 0.2 1.3 1 0 0 1 1 1 0 Laminin Domain I LPP PF04728.13 EOO00535.1 - 0.072 13.5 0.9 0.26 11.7 0.9 1.9 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DUF1722 PF08349.11 EOO00535.1 - 0.096 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Aida_N PF08910.10 EOO00535.1 - 0.11 12.9 0.1 0.32 11.4 0.1 1.9 1 0 0 1 1 1 0 Aida N-terminus DisA-linker PF10635.9 EOO00535.1 - 0.18 11.6 0.6 2.5 7.9 0.1 2.4 2 0 0 2 2 2 0 DisA bacterial checkpoint controller linker region Methyltransf_25 PF13649.6 EOO00536.1 - 1.8e-07 31.8 0.0 3.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO00536.1 - 8.4e-07 29.6 0.0 1.7e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EOO00536.1 - 0.0015 18.4 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO00536.1 - 0.0022 17.8 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EOO00536.1 - 0.0048 16.3 0.0 0.0065 15.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EOO00536.1 - 0.01 16.5 0.0 0.018 15.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain WW PF00397.26 EOO00537.1 - 1.5e-11 44.2 0.1 4e-11 42.8 0.1 1.8 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 EOO00537.1 - 0.001 18.1 0.2 0.014 14.4 0.1 2.1 2 0 0 2 2 2 1 PhoD-like phosphatase Velvet PF11754.8 EOO00539.1 - 5.8e-93 311.4 0.2 1.4e-92 310.2 0.0 1.5 2 0 0 2 2 2 1 Velvet factor MSC PF09402.10 EOO00540.1 - 8.3e-117 390.4 0.0 1.1e-116 390.0 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EOO00540.1 - 5.2e-17 61.3 0.1 1.2e-16 60.1 0.0 1.7 2 0 0 2 2 2 1 HeH/LEM domain Thymopoietin PF08198.11 EOO00540.1 - 0.0031 17.1 0.0 0.0067 16.0 0.0 1.5 1 0 0 1 1 1 1 Thymopoietin protein DUF3887 PF13026.6 EOO00540.1 - 0.099 13.5 0.0 0.2 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) COQ7 PF03232.13 EOO00540.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 FliN_N PF16973.5 EOO00540.1 - 0.26 11.2 2.7 0.25 11.2 0.2 2.3 2 0 0 2 2 2 0 Flagellar motor switch protein FliN N-terminal PMM PF03332.13 EOO00541.1 - 1.5e-98 328.9 0.1 2e-98 328.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EOO00541.1 - 0.019 14.7 0.0 0.1 12.3 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RVT_1 PF00078.27 EOO00543.1 - 5.9e-18 65.2 0.2 9.9e-13 48.1 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) ANAPC4 PF12896.7 EOO00543.1 - 0.029 13.9 0.6 0.062 12.8 0.1 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Sugar_tr PF00083.24 EOO00544.1 - 7.2e-58 196.5 8.9 4.2e-45 154.4 1.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO00544.1 - 9.1e-10 38.0 5.3 1.2e-09 37.6 5.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 EOO00545.1 - 6.8e-14 51.6 6.4 9.3e-14 51.1 3.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Transgly_assoc PF04226.13 EOO00545.1 - 0.02 15.2 0.4 0.27 11.5 0.3 2.5 2 0 0 2 2 2 0 Transglycosylase associated protein Cytochrom_B561 PF03188.16 EOO00545.1 - 0.032 14.4 3.8 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 DUF3602 PF12223.8 EOO00546.1 - 4.7e-17 62.4 16.1 1.4e-12 48.1 0.8 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DNA_gyraseA_C PF03989.13 EOO00546.1 - 0.23 10.9 3.0 6.8 6.3 0.0 2.9 3 0 0 3 3 3 0 DNA gyrase C-terminal domain, beta-propeller Sulfatase PF00884.23 EOO00547.1 - 2.7e-16 59.9 0.0 4.9e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 EOO00547.1 - 0.00035 19.3 0.0 0.00035 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 EOO00547.1 - 0.0012 19.0 0.6 0.0012 19.0 0.6 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4976) Helicase_C PF00271.31 EOO00548.1 - 4.1e-22 78.6 0.0 9.1e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO00548.1 - 5.3e-06 26.5 0.0 1.2e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EOO00548.1 - 0.0064 16.3 0.0 0.024 14.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EOO00548.1 - 0.063 12.9 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Nucleo_P87 PF07267.11 EOO00548.1 - 8.2 5.2 6.4 17 4.1 6.4 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3605 PF12239.8 EOO00549.1 - 7e-57 192.1 2.1 8.5e-57 191.8 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) MBOAT_2 PF13813.6 EOO00550.1 - 9.9e-14 51.4 1.9 9.9e-14 51.4 1.9 2.6 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Glyco_hydro_7 PF00840.20 EOO00551.1 - 1.2e-201 670.1 17.5 1.4e-201 669.9 17.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Hist_deacetyl PF00850.19 EOO00552.1 - 2.6e-78 263.6 0.0 3.5e-78 263.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Herpes_gE PF02480.16 EOO00553.1 - 0.0056 15.5 0.5 0.0096 14.7 0.3 1.4 1 1 0 1 1 1 1 Alphaherpesvirus glycoprotein E CYYR1 PF10873.8 EOO00553.1 - 0.0077 16.7 2.0 0.012 16.1 0.0 2.0 2 0 0 2 2 2 1 Cysteine and tyrosine-rich protein 1 DAG1 PF05454.11 EOO00553.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DAP10 PF07213.11 EOO00553.1 - 0.066 13.2 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 DAP10 membrane protein DUF4342 PF14242.6 EOO00553.1 - 0.072 13.1 0.7 0.14 12.1 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) EphA2_TM PF14575.6 EOO00553.1 - 0.11 13.4 0.0 0.17 12.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cytomega_TRL10 PF06084.11 EOO00553.1 - 0.14 12.2 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein TMEM154 PF15102.6 EOO00553.1 - 2.5 8.0 3.8 9.8 6.1 3.8 2.1 1 1 0 1 1 1 0 TMEM154 protein family RhoGEF PF00621.20 EOO00554.1 - 1.3e-32 113.5 0.7 4.8e-32 111.7 0.0 2.2 2 1 0 2 2 2 1 RhoGEF domain BAR PF03114.18 EOO00554.1 - 3.3e-08 33.5 2.1 4.9e-08 32.9 0.2 2.3 3 0 0 3 3 3 1 BAR domain LPD13 PF18825.1 EOO00554.1 - 0.022 14.5 0.0 0.059 13.1 0.0 1.7 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 13 ASL_C PF08328.11 EOO00554.1 - 0.066 13.3 1.5 0.21 11.7 0.3 2.4 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal Seryl_tRNA_N PF02403.22 EOO00554.1 - 1.1 9.5 4.2 4.4 7.6 0.7 2.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FR47 PF08445.10 EOO00555.1 - 0.17 11.8 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein MFS_1 PF07690.16 EOO00556.1 - 6.7e-15 54.9 35.2 1.3e-12 47.4 14.3 3.3 1 1 2 3 3 3 3 Major Facilitator Superfamily PIRT PF15099.6 EOO00556.1 - 0.039 13.5 0.2 0.039 13.5 0.2 1.9 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family 2-Hacid_dh_C PF02826.19 EOO00557.1 - 1.2e-47 161.6 0.2 1.5e-47 161.2 0.2 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EOO00557.1 - 3.4e-05 24.1 0.1 5.4e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.15 EOO00557.1 - 0.0051 17.2 0.0 4.1 7.9 0.0 2.2 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain GFO_IDH_MocA PF01408.22 EOO00557.1 - 0.063 14.1 0.0 0.16 12.8 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold HTH_1 PF00126.27 EOO00557.1 - 0.16 12.0 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family URO-D PF01208.17 EOO00558.1 - 1.3e-128 429.0 0.0 1.5e-128 428.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Pex26 PF07163.12 EOO00558.1 - 0.14 11.4 0.2 0.21 10.8 0.2 1.2 1 0 0 1 1 1 0 Pex26 protein Sugar_tr PF00083.24 EOO00559.1 - 2.3e-49 168.5 16.9 2.9e-46 158.3 14.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter HLH PF00010.26 EOO00560.1 - 2.4e-16 59.4 0.1 4.9e-16 58.4 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4140 PF13600.6 EOO00560.1 - 0.87 10.1 3.6 34 4.9 1.0 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.8 EOO00560.1 - 3.6 7.7 11.7 0.96 9.5 2.4 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ING PF12998.7 EOO00561.1 - 5.8e-22 78.2 2.1 8.4e-22 77.7 2.1 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EOO00561.1 - 2.9e-05 23.8 8.3 5.8e-05 22.9 8.3 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EOO00561.1 - 0.14 12.4 1.3 0.27 11.5 1.3 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF2552 PF10827.8 EOO00561.1 - 0.21 11.8 0.1 0.74 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2552) zf-RING_2 PF13639.6 EOO00561.1 - 0.27 11.6 6.2 0.48 10.8 6.2 1.4 1 0 0 1 1 1 0 Ring finger domain MFS_1 PF07690.16 EOO00562.1 - 2.4e-18 66.2 9.8 2.4e-18 66.2 9.8 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4407 PF14362.6 EOO00562.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cdc6_C PF09079.11 EOO00563.1 - 1.3e-06 28.3 0.0 4.4e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 EOO00563.1 - 9e-06 26.0 0.6 6.7e-05 23.2 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EOO00563.1 - 4.4e-05 23.9 0.1 0.00014 22.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 EOO00563.1 - 0.00061 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain TniB PF05621.11 EOO00563.1 - 0.0083 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein Arrestin_N PF00339.29 EOO00564.1 - 2.1e-11 44.1 0.0 2.8e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Fungal_trans PF04082.18 EOO00565.1 - 2e-08 33.6 0.4 6.4e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EOO00565.1 - 4.6e-08 33.0 8.7 7.9e-08 32.3 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TAP_C PF03943.13 EOO00566.1 - 5.3e-16 58.0 0.0 9.9e-16 57.1 0.0 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.7 EOO00566.1 - 4.2e-05 23.8 0.1 0.003 17.9 0.0 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) RRM_9 PF18444.1 EOO00566.1 - 0.00022 21.0 0.2 0.00065 19.5 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif LRR_8 PF13855.6 EOO00566.1 - 0.0046 16.7 0.9 0.015 15.1 0.2 2.4 2 0 0 2 2 2 1 Leucine rich repeat NTF2 PF02136.20 EOO00566.1 - 0.033 14.8 0.0 0.092 13.3 0.0 1.8 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain HSP20 PF00011.21 EOO00568.1 - 1.7e-11 44.2 0.1 2.6e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EOO00568.1 - 0.14 11.7 0.2 1.3 8.6 0.2 2.3 1 1 0 1 1 1 0 HSP20-like domain found in ArsA Pectate_lyase_3 PF12708.7 EOO00569.1 - 0.0083 16.0 1.2 0.14 12.0 1.2 2.4 1 1 0 1 1 1 1 Pectate lyase superfamily protein PhyH PF05721.13 EOO00570.1 - 9.3e-22 78.3 0.0 1.2e-21 77.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EOO00570.1 - 0.087 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Cupin_1 PF00190.22 EOO00570.1 - 0.17 11.5 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Cupin SirA PF10747.9 EOO00570.1 - 0.2 12.0 0.0 0.33 11.3 0.0 1.2 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA HET PF06985.11 EOO00571.1 - 1.1e-31 110.2 0.4 1.5e-31 109.7 0.4 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aldo_ket_red PF00248.21 EOO00572.1 - 8.8e-64 215.5 0.0 1.1e-63 215.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Laminin_G_3 PF13385.6 EOO00573.1 - 0.0071 16.5 0.1 0.038 14.1 0.0 2.3 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily UDPGP PF01704.18 EOO00574.1 - 8.4e-192 637.3 0.1 9.9e-192 637.1 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.13 EOO00574.1 - 0.1 12.8 0.0 0.34 11.1 0.0 1.9 2 0 0 2 2 2 0 Pilus assembly protein, PilO ADH_zinc_N PF00107.26 EOO00575.1 - 4.2e-18 65.6 0.1 6.6e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EOO00575.1 - 1.3e-16 60.5 1.1 1.6e-14 53.7 0.4 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EOO00575.1 - 0.0012 19.9 0.0 0.002 19.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 EOO00575.1 - 0.15 11.8 0.7 0.29 10.8 0.7 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase FolB PF02152.18 EOO00576.1 - 7.5e-23 81.2 0.0 2e-18 67.0 0.0 2.6 3 0 0 3 3 3 2 Dihydroneopterin aldolase Podoplanin PF05808.11 EOO00577.1 - 0.00075 19.6 0.4 0.0019 18.3 0.4 1.6 1 0 0 1 1 1 1 Podoplanin DUF4690 PF15756.5 EOO00577.1 - 0.0046 17.5 1.0 0.014 16.0 1.0 1.8 1 0 0 1 1 1 1 Small Novel Rich in Cartilage TMEM154 PF15102.6 EOO00577.1 - 0.08 12.8 0.1 0.23 11.3 0.1 1.8 1 0 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.6 EOO00577.1 - 0.084 11.7 0.1 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 Amnionless MGC-24 PF05283.11 EOO00577.1 - 0.37 11.2 4.8 0.18 12.3 1.1 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CD34_antigen PF06365.12 EOO00577.1 - 0.49 9.9 4.7 1.3 8.6 0.1 2.9 3 0 0 3 3 3 0 CD34/Podocalyxin family Orf78 PF06024.12 EOO00577.1 - 1.4 9.3 0.0 1.4 9.3 0.0 2.3 3 0 0 3 3 3 0 Orf78 (ac78) PIF1 PF05970.14 EOO00579.1 - 1.8e-21 76.7 0.0 2.2e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EOO00579.1 - 1.7e-07 31.1 0.0 1.4e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EOO00579.1 - 0.00075 19.9 0.0 0.0018 18.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EOO00579.1 - 0.061 13.7 0.6 0.15 12.5 0.6 1.9 1 1 0 1 1 1 0 AAA ATPase domain PhyH PF05721.13 EOO00580.1 - 2.9e-07 31.0 0.0 0.00018 21.9 0.0 2.1 1 1 1 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) HOCHOB PF17943.1 EOO00582.1 - 0.014 16.1 0.7 0.031 15.0 0.0 1.9 2 0 0 2 2 2 0 Homeobox-cysteine loop-homeobox ABC1 PF03109.16 EOO00584.1 - 2.5e-20 72.8 0.0 1.5e-11 44.5 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 EOO00584.1 - 0.052 13.5 0.4 0.12 12.3 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_18 PF00704.28 EOO00585.1 - 4.7e-81 272.9 7.8 6e-81 272.6 7.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LOR PF04525.12 EOO00586.1 - 1.2e-20 73.9 0.1 2.1e-20 73.1 0.1 1.6 1 1 0 1 1 1 1 LURP-one-related DUF4378 PF14309.6 EOO00586.1 - 0.17 12.2 0.0 0.22 11.9 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4378) COesterase PF00135.28 EOO00587.1 - 1.9e-64 218.4 10.0 1.2e-62 212.5 10.0 2.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EOO00587.1 - 0.006 16.5 0.1 0.036 13.9 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF4387 PF14330.6 EOO00589.1 - 1.9e-36 124.6 0.0 3e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 EOO00589.1 - 0.15 10.8 0.0 0.27 9.9 0.0 1.5 1 1 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA AtuA PF07287.11 EOO00590.1 - 1.8e-36 125.6 0.0 2.2e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Transp_cyt_pur PF02133.15 EOO00591.1 - 1.9e-94 317.0 37.6 2.3e-94 316.6 37.6 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NCOA_u2 PF16665.5 EOO00592.1 - 2.2 8.6 7.0 0.26 11.6 2.4 1.7 2 0 0 2 2 2 0 Unstructured region on nuclear receptor coactivator protein AIM24 PF01987.17 EOO00593.1 - 1.1e-36 126.5 0.0 1.5e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Abhydrolase_1 PF00561.20 EOO00594.1 - 1e-09 38.5 0.0 2.7e-09 37.0 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EOO00594.1 - 3.7e-05 24.4 0.0 5.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EOO00594.1 - 0.0095 15.2 0.0 0.039 13.2 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Phage_holin_2_2 PF10746.9 EOO00594.1 - 0.083 12.6 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Phage holin T7 family, holin superfamily II SGL PF08450.12 EOO00595.1 - 3.3e-60 203.7 0.1 3.9e-60 203.5 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EOO00595.1 - 0.013 15.6 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Arylesterase PD40 PF07676.12 EOO00595.1 - 0.056 13.4 0.3 0.4 10.7 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat NHL PF01436.21 EOO00595.1 - 0.17 12.0 0.0 0.51 10.5 0.0 1.9 2 0 0 2 2 2 0 NHL repeat Reg_prop PF07494.11 EOO00595.1 - 4.1 8.0 5.9 3.1 8.3 0.1 3.5 4 0 0 4 4 4 0 Two component regulator propeller Mannosidase_ig PF17786.1 EOO00596.1 - 1.2e-18 67.5 0.0 1.2e-17 64.3 0.0 2.6 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EOO00596.1 - 1.2e-06 29.2 0.0 3.5e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 EOO00596.1 - 6e-05 22.7 0.0 0.00019 21.1 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 EOO00596.1 - 0.013 14.6 0.0 0.034 13.2 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain TRI12 PF06609.13 EOO00597.1 - 1.3e-09 37.1 3.6 1.6e-09 36.8 3.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.25 EOO00598.1 - 2.4e-30 105.4 0.0 4.3e-30 104.6 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO00598.1 - 1.4e-23 83.7 0.1 1.9e-23 83.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO00598.1 - 4.1e-11 43.1 0.0 3.5e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EOO00598.1 - 8e-08 31.8 0.0 1e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EOO00598.1 - 5.1e-05 22.9 0.1 0.0011 18.5 0.2 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family ThiF PF00899.21 EOO00598.1 - 0.0002 20.8 0.2 0.00041 19.8 0.1 1.5 1 1 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EOO00598.1 - 0.00069 19.7 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EOO00598.1 - 0.012 16.1 0.1 0.059 14.0 0.2 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 EOO00598.1 - 0.075 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain THF_DHG_CYH_C PF02882.19 EOO00598.1 - 0.086 12.2 0.2 0.17 11.2 0.2 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Anophelin PF10731.9 EOO00599.1 - 0.22 11.4 2.1 0.62 10.0 2.1 1.7 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito NmrA PF05368.13 EOO00600.1 - 9.5e-13 48.2 0.0 1.2e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family AMP-binding PF00501.28 EOO00601.1 - 0 2027.0 4.7 3.1e-82 276.4 0.0 8.3 8 0 0 8 8 8 8 AMP-binding enzyme Condensation PF00668.20 EOO00601.1 - 0 1608.7 0.0 5.1e-57 193.6 0.0 14.9 12 3 0 12 12 12 12 Condensation domain PP-binding PF00550.25 EOO00601.1 - 2.3e-80 264.9 9.7 1.1e-10 41.7 0.1 9.1 8 0 0 8 8 8 8 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EOO00601.1 - 1.7e-20 73.7 0.1 0.21 12.6 0.0 9.4 8 0 0 8 8 8 6 AMP-binding enzyme C-terminal domain FMN_dh PF01070.18 EOO00602.1 - 1.6e-90 303.6 1.3 1.4e-86 290.6 0.5 2.7 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EOO00602.1 - 8.9e-06 25.1 0.1 1.6e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EOO00602.1 - 0.00014 21.0 0.1 0.00045 19.3 0.0 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 EOO00602.1 - 0.033 13.5 0.1 1.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG NMO PF03060.15 EOO00602.1 - 0.038 13.4 0.1 0.056 12.8 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase AMP-binding PF00501.28 EOO00603.1 - 0 1729.6 11.9 2.8e-84 283.2 0.0 8.6 8 1 1 9 9 9 8 AMP-binding enzyme Condensation PF00668.20 EOO00603.1 - 0 1376.5 0.0 4.1e-51 174.1 0.0 12.5 10 3 1 11 11 11 11 Condensation domain PP-binding PF00550.25 EOO00603.1 - 3.8e-70 232.2 23.3 6.4e-10 39.3 0.0 8.9 8 0 0 8 8 8 8 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EOO00603.1 - 4e-12 46.9 0.2 9.6 7.3 0.0 7.8 7 0 0 7 7 7 4 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EOO00603.1 - 0.0044 15.7 0.0 8.1 5.0 0.0 3.7 4 0 0 4 4 4 2 Transferase family AMP-binding PF00501.28 EOO00604.1 - 0 1588.3 3.7 2.2e-82 276.9 0.0 6.3 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 EOO00604.1 - 0 1322.4 0.0 2.5e-57 194.6 0.0 14.1 12 3 1 13 13 13 13 Condensation domain PP-binding PF00550.25 EOO00604.1 - 6.3e-55 183.4 17.2 4e-08 33.5 0.2 7.8 8 0 0 8 8 8 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EOO00604.1 - 3.1e-14 53.7 0.1 0.37 11.8 0.0 7.2 6 0 0 6 6 6 4 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EOO00604.1 - 0.071 11.7 0.0 0.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Transferase family DUF5122 PF17164.4 EOO00604.1 - 1.1 9.6 4.1 1.6e+02 2.7 0.1 4.9 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller Dynamin_M PF01031.20 EOO00605.1 - 7.4e-23 81.2 0.9 2.1e-22 79.7 0.8 1.8 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EOO00605.1 - 8.7e-15 55.2 0.0 2e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin family DUF1825 PF08855.10 EOO00605.1 - 0.033 14.1 0.1 0.1 12.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) FliH PF02108.16 EOO00605.1 - 0.1 12.6 1.7 1.6 8.8 0.1 2.8 1 1 1 2 2 2 0 Flagellar assembly protein FliH CHDCT2 PF08074.11 EOO00605.1 - 0.11 12.7 0.8 3.5 7.8 0.0 2.5 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Apolipoprotein PF01442.18 EOO00605.1 - 0.43 10.4 6.2 0.1 12.5 0.8 2.4 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain ABC_membrane PF00664.23 EOO00606.1 - 6.6e-44 150.6 11.9 8.4e-44 150.3 11.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EOO00606.1 - 2.4e-34 118.8 0.0 8.8e-34 117.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EOO00606.1 - 8e-06 25.4 0.0 0.0032 16.9 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EOO00606.1 - 3.9e-05 24.1 0.0 0.00011 22.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EOO00606.1 - 0.0004 20.7 0.0 0.0065 16.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EOO00606.1 - 0.00053 19.9 0.0 0.015 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 EOO00606.1 - 0.00088 19.3 0.0 0.01 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EOO00606.1 - 0.0014 18.7 0.0 0.0071 16.4 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EOO00606.1 - 0.003 17.5 0.0 0.0098 15.8 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 EOO00606.1 - 0.01 15.6 0.0 0.029 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EOO00606.1 - 0.01 15.1 0.0 0.035 13.4 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 EOO00606.1 - 0.012 15.8 0.0 0.032 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EOO00606.1 - 0.016 15.0 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EOO00606.1 - 0.02 15.3 0.0 0.17 12.3 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EOO00606.1 - 0.028 14.6 0.0 0.097 12.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 EOO00606.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EOO00606.1 - 0.047 13.6 0.1 0.55 10.1 0.0 2.7 3 0 0 3 3 2 0 NACHT domain Rad17 PF03215.15 EOO00606.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain SbcCD_C PF13558.6 EOO00606.1 - 0.058 13.6 0.4 1.2 9.4 0.4 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EOO00606.1 - 0.06 13.8 0.1 0.13 12.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 EOO00606.1 - 0.062 13.9 0.0 0.23 12.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 EOO00606.1 - 0.067 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 EOO00606.1 - 0.077 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_10 PF12846.7 EOO00606.1 - 0.14 11.0 0.1 0.34 9.8 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.22 EOO00606.1 - 0.17 12.3 0.0 0.62 10.5 0.0 2.0 2 0 0 2 2 1 0 RNA helicase CENP-B_dimeris PF09026.10 EOO00607.1 - 2 8.9 8.3 4.9 7.6 4.7 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Beta_helix PF13229.6 EOO00608.1 - 2.4e-08 34.0 20.3 3e-06 27.2 15.4 3.8 2 1 0 2 2 2 2 Right handed beta helix region DUF2075 PF09848.9 EOO00608.1 - 0.22 10.7 0.0 0.31 10.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.23 EOO00609.1 - 2e-31 109.3 0.1 3.6e-31 108.5 0.1 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EOO00609.1 - 1.4e-22 80.3 0.0 8.7e-22 77.7 0.0 2.2 3 0 0 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.23 EOO00609.1 - 1.9e-08 34.4 0.1 6.4e-05 23.0 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EOO00609.1 - 0.0021 17.6 0.0 0.15 11.6 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_21 PF13304.6 EOO00609.1 - 0.0026 17.6 1.2 0.019 14.8 0.0 2.7 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 EOO00609.1 - 0.018 15.2 0.1 0.59 10.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 EOO00609.1 - 0.025 14.3 0.1 0.065 12.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EOO00609.1 - 0.034 13.9 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EOO00609.1 - 0.05 14.0 0.3 0.67 10.3 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EOO00609.1 - 0.051 14.1 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF1045 PF06299.12 EOO00609.1 - 0.13 12.3 0.0 0.66 9.9 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1045) VCBS PF13517.6 EOO00610.1 - 2.1e-32 111.5 44.3 1.4e-09 38.4 2.2 8.7 2 2 6 8 8 8 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 EOO00610.1 - 1.8e-11 44.8 0.3 4.8e-11 43.4 0.1 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.8 EOO00610.1 - 4e-08 32.8 9.9 0.097 12.0 0.0 6.6 5 2 1 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 EOO00610.1 - 0.00089 19.3 0.4 0.00089 19.3 0.4 7.6 8 0 0 8 8 8 4 FG-GAP repeat Dockerin_1 PF00404.18 EOO00610.1 - 0.11 12.7 7.0 4.3 7.6 0.2 4.7 4 0 0 4 4 4 0 Dockerin type I domain Ntox34 PF15606.6 EOO00610.1 - 0.12 12.5 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial toxin 34 Microtub_bd PF16796.5 EOO00611.1 - 0.00034 20.6 0.0 0.00042 20.3 0.0 1.1 1 0 0 1 1 1 1 Microtubule binding Kinesin PF00225.23 EOO00611.1 - 0.00047 19.2 0.0 0.0005 19.1 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain AA_permease PF00324.21 EOO00612.1 - 1.3e-105 353.7 36.6 1.6e-105 353.5 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EOO00612.1 - 2.1e-24 86.2 40.2 2.9e-24 85.7 40.2 1.2 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 EOO00613.1 - 4.5e-30 104.8 74.7 1.6e-23 83.2 39.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO00613.1 - 9.5e-07 28.0 39.6 2.5e-05 23.4 5.3 3.7 2 2 2 4 4 4 2 Sugar (and other) transporter MFS_1_like PF12832.7 EOO00613.1 - 8.8e-05 21.5 3.0 8.8e-05 21.5 3.0 3.0 2 2 1 3 3 3 2 MFS_1 like family Kinesin PF00225.23 EOO00614.1 - 9.3e-56 189.1 0.1 1.3e-55 188.7 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain HHH_3 PF12836.7 EOO00614.1 - 0.00083 19.6 0.0 0.0041 17.3 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif PBP1_TM PF14812.6 EOO00614.1 - 0.033 14.6 0.7 0.033 14.6 0.7 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aminotran_5 PF00266.19 EOO00615.1 - 6.7e-12 45.0 0.0 6.8e-11 41.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EOO00615.1 - 1.3e-05 24.0 0.0 2.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EOO00615.1 - 0.0019 17.6 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_L32e PF01655.18 EOO00616.1 - 3.3e-49 165.8 1.3 3.3e-49 165.8 1.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L32 Oxidored_FMN PF00724.20 EOO00617.1 - 2.7e-37 128.8 0.0 3.4e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Glyco_hydro_10 PF00331.20 EOO00618.1 - 1.9e-81 273.6 0.1 2.3e-81 273.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Botulinum_HA-17 PF05588.11 EOO00618.1 - 1.4 9.0 4.5 2.5 8.2 0.6 2.4 1 1 1 2 2 2 0 Clostridium botulinum HA-17 domain Aldedh PF00171.22 EOO00619.1 - 8.2e-178 591.6 0.8 1e-177 591.3 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Adenosine_kin PF04008.14 EOO00619.1 - 0.08 12.7 0.1 2.3 8.0 0.1 2.6 2 0 0 2 2 2 0 Adenosine specific kinase PYNP_C PF07831.13 EOO00619.1 - 0.13 11.9 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain DEAD PF00270.29 EOO00620.1 - 8.5e-50 168.9 0.0 8.4e-49 165.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EOO00620.1 - 6.2e-31 107.0 0.0 2.5e-30 105.0 0.0 2.0 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO00620.1 - 2e-05 24.7 0.0 8.7e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EOO00620.1 - 0.00045 20.6 0.0 0.19 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain GRP PF07172.11 EOO00620.1 - 0.0008 20.1 3.8 0.0008 20.1 3.8 3.4 2 1 1 3 3 3 1 Glycine rich protein family UTP25 PF06862.12 EOO00620.1 - 0.0052 15.6 0.0 0.96 8.1 0.0 2.4 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Catalase-rel PF06628.12 EOO00620.1 - 0.24 11.7 0.5 8.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Catalase-related immune-responsive AAA_22 PF13401.6 EOO00620.1 - 0.69 10.2 2.1 44 4.3 0.0 3.4 3 1 1 4 4 4 0 AAA domain Ribosomal_L30_N PF08079.12 EOO00621.1 - 1.1e-27 96.1 17.9 1.9e-27 95.3 17.9 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EOO00621.1 - 1e-16 60.5 2.8 1e-16 60.5 2.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Clathrin_lg_ch PF01086.17 EOO00621.1 - 1.6 8.8 9.3 2.2 8.3 9.3 1.2 1 0 0 1 1 1 0 Clathrin light chain CRIM PF16978.5 EOO00622.1 - 2.1e-48 164.0 0.0 4.7e-48 162.9 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EOO00622.1 - 3.3e-31 107.8 0.0 8.5e-31 106.5 0.0 1.7 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 EOO00622.1 - 0.0067 16.6 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain Bys1 PF04681.12 EOO00625.1 - 8e-14 51.9 1.9 9.4e-14 51.6 1.9 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Cellulase PF00150.18 EOO00626.1 - 1.3e-56 192.1 1.1 1.6e-56 191.8 1.1 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1759 PF03564.15 EOO00626.1 - 0.17 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Arrestin_C PF02752.22 EOO00627.1 - 7.6e-12 45.8 0.0 5e-11 43.2 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EOO00627.1 - 0.0048 16.9 0.1 0.0086 16.1 0.1 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SNF2_N PF00176.23 EOO00628.1 - 1.2e-66 224.8 0.1 2.6e-66 223.8 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EOO00628.1 - 9.1e-22 77.5 0.0 2.4e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO00628.1 - 4.3e-06 26.8 0.0 1.3e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EOO00628.1 - 0.00078 18.7 0.0 0.0017 17.6 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_11 PF13086.6 EOO00628.1 - 2.4 7.9 9.2 1.8 8.3 0.6 3.3 2 1 0 2 2 2 0 AAA domain LPMO_10 PF03067.15 EOO00629.1 - 1e-07 32.8 0.0 1.5e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading MFS_1 PF07690.16 EOO00630.1 - 2.7e-30 105.5 15.9 2.7e-30 105.5 15.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO00630.1 - 2.4e-05 23.4 15.5 0.00011 21.2 15.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EOO00630.1 - 0.0013 18.1 2.7 0.0013 18.1 2.7 2.1 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EOO00630.1 - 0.0018 16.6 2.9 0.0018 16.6 2.9 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family JAB PF01398.21 EOO00631.1 - 2.8e-29 101.5 0.0 4.1e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EOO00631.1 - 4.4e-25 88.4 0.0 7.3e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EOO00631.1 - 0.0015 18.3 0.0 0.0034 17.1 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain DUF883 PF05957.13 EOO00632.1 - 0.015 15.9 1.1 5.3 7.7 0.0 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) LPP PF04728.13 EOO00632.1 - 3.4 8.1 10.1 13 6.2 1.7 3.1 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Ribosomal_S11 PF00411.19 EOO00634.1 - 1.9e-46 157.0 1.1 2.4e-46 156.7 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EOO00634.1 - 0.083 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) LMBR1 PF04791.16 EOO00635.1 - 2.6e-119 399.5 0.1 3e-119 399.3 0.1 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Phage_P2_GpE PF06528.12 EOO00635.1 - 0.11 12.0 0.1 0.41 10.2 0.1 2.0 1 0 0 1 1 1 0 Phage P2 GpE DUF1772 PF08592.11 EOO00635.1 - 9.6 6.5 13.4 2.5 8.4 1.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Sugar_tr PF00083.24 EOO00636.1 - 5.2e-90 302.5 18.8 6.1e-90 302.3 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO00636.1 - 1.1e-20 73.9 45.2 5.3e-15 55.2 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EOO00636.1 - 0.00022 19.8 4.1 0.00048 18.7 4.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EOO00636.1 - 0.029 12.7 9.4 0.84 7.8 0.5 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Ricin_B_lectin PF00652.22 EOO00637.1 - 1.1e-05 25.6 0.0 0.042 14.1 0.0 2.7 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain F-box-like PF12937.7 EOO00638.1 - 0.016 15.1 1.6 0.016 15.1 1.6 2.1 2 0 0 2 2 2 0 F-box-like LRR_4 PF12799.7 EOO00638.1 - 0.023 15.1 6.6 15 6.1 0.7 5.0 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Lac_bphage_repr PF06543.12 EOO00638.1 - 0.044 13.8 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor LRR_8 PF13855.6 EOO00638.1 - 0.97 9.2 7.4 4.4 7.2 0.3 3.8 3 2 1 4 4 4 0 Leucine rich repeat Sulfotransfer_4 PF17784.1 EOO00639.1 - 1.7e-54 184.9 0.3 2e-54 184.7 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EOO00639.1 - 0.001 19.5 0.0 0.0014 19.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family CorA PF01544.18 EOO00640.1 - 2e-20 73.3 3.0 4.6e-17 62.3 0.5 2.4 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein TPR_1 PF00515.28 EOO00641.1 - 1.3e-16 59.6 6.7 1.7e-08 33.9 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EOO00641.1 - 1.1e-15 56.4 7.5 2e-06 27.4 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 EOO00641.1 - 6.6e-12 45.6 0.7 2.3e-07 31.0 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EOO00641.1 - 6.7e-11 41.5 3.4 7.1e-06 25.8 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EOO00641.1 - 4.1e-09 36.5 0.7 0.088 13.5 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EOO00641.1 - 1.9e-08 33.8 0.5 3.9e-06 26.5 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EOO00641.1 - 3.5e-08 33.0 1.5 1.2e-05 24.9 0.2 3.7 1 1 2 3 3 3 1 TPR repeat PB1 PF00564.24 EOO00641.1 - 6.8e-07 29.1 0.3 1.3e-06 28.3 0.3 1.5 1 0 0 1 1 1 1 PB1 domain TPR_9 PF13371.6 EOO00641.1 - 2.3e-05 24.4 0.1 0.16 12.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EOO00641.1 - 0.0001 22.9 1.1 0.0082 16.8 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EOO00641.1 - 0.00013 21.7 1.0 0.2 11.6 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EOO00641.1 - 0.00018 21.7 0.2 0.27 11.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EOO00641.1 - 0.0025 18.5 0.6 0.2 12.6 0.0 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat DUF3808 PF10300.9 EOO00641.1 - 0.067 11.9 0.1 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_19 PF14559.6 EOO00641.1 - 0.077 13.5 0.1 0.91 10.1 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EOO00641.1 - 0.11 13.2 0.1 47 5.0 0.0 3.6 3 1 0 3 3 2 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EOO00641.1 - 0.16 12.1 0.1 0.45 10.6 0.1 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 RICTOR_N PF14664.6 EOO00642.1 - 1.8e-93 313.5 1.7 3e-93 312.8 0.4 2.0 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 EOO00642.1 - 4.8e-39 132.3 0.0 1e-36 124.8 0.0 3.8 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 EOO00642.1 - 5.9e-33 113.5 0.2 6.7e-30 103.7 0.0 4.2 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 EOO00642.1 - 2.6e-29 101.3 0.1 1.1e-27 96.1 0.1 3.4 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 EOO00642.1 - 3.6e-15 55.8 8.9 1e-14 54.4 8.9 1.8 1 0 0 1 1 1 1 Hr1 repeat DUF2203 PF09969.9 EOO00642.1 - 1.3 9.8 4.7 4.4 8.1 4.7 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Uds1 PF15456.6 EOO00642.1 - 3.7 7.7 11.7 0.14 12.3 5.6 1.8 2 0 0 2 2 2 0 Up-regulated During Septation Ribosomal_L13 PF00572.18 EOO00645.1 - 5.2e-40 136.6 0.0 9.2e-40 135.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L13 MFS_1 PF07690.16 EOO00646.1 - 8.5e-15 54.5 17.0 6.5e-14 51.6 14.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SR-25 PF10500.9 EOO00646.1 - 0.067 12.8 7.3 0.12 12.0 7.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein S1FA PF04689.13 EOO00646.1 - 0.09 12.9 0.7 0.99 9.6 0.0 2.6 2 0 0 2 2 2 0 DNA binding protein S1FA Chorion_2 PF03964.15 EOO00646.1 - 0.11 13.4 1.3 0.22 12.4 1.3 1.5 1 0 0 1 1 1 0 Chorion family 2 PAP2 PF01569.21 EOO00646.1 - 0.28 10.9 9.4 0.44 10.3 6.6 2.8 2 1 0 2 2 2 0 PAP2 superfamily MtN3_slv PF03083.16 EOO00646.1 - 0.59 10.2 10.3 0.083 12.9 1.1 2.8 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange RNA_polI_A34 PF08208.11 EOO00646.1 - 1.6 8.8 7.3 2.7 8.1 7.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TctB PF07331.11 EOO00646.1 - 1.6 9.0 16.1 8 6.7 14.3 2.6 1 1 2 3 3 3 0 Tripartite tricarboxylate transporter TctB family GSG-1 PF07803.11 EOO00647.1 - 0.21 11.5 0.0 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 GSG1-like protein RRM_1 PF00076.22 EOO00648.1 - 1.4e-16 60.0 0.0 2.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EOO00648.1 - 4.5e-05 23.0 0.0 6.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 EOO00648.1 - 0.0017 18.2 0.1 0.0032 17.4 0.1 1.5 1 0 0 1 1 1 1 RL domain Nup35_RRM_2 PF14605.6 EOO00648.1 - 0.002 18.1 0.1 0.0034 17.3 0.1 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 EOO00648.1 - 0.016 15.2 0.2 0.1 12.7 0.0 2.0 1 1 0 2 2 2 0 Limkain b1 RRM_7 PF16367.5 EOO00648.1 - 0.048 13.8 0.1 0.11 12.6 0.1 1.7 1 1 0 1 1 1 0 RNA recognition motif BRF1 PF07741.13 EOO00648.1 - 4.2 7.8 7.9 6.6 7.1 5.8 2.0 2 0 0 2 2 2 0 Brf1-like TBP-binding domain PDH PF02153.17 EOO00649.1 - 1.9e-14 53.3 0.0 2.8e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase Polysacc_deac_1 PF01522.21 EOO00650.1 - 3.7e-27 94.7 0.0 6.6e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EOO00650.1 - 1.2e-09 38.4 53.4 1.1e-05 25.8 16.4 3.3 3 0 0 3 3 3 2 Chitin recognition protein Rad9 PF04139.13 EOO00651.1 - 3.2e-05 23.5 0.0 3.5e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Rad9 Polyoma_coat PF00718.20 EOO00651.1 - 0.017 14.4 0.0 0.021 14.1 0.0 1.0 1 0 0 1 1 1 0 Polyomavirus coat protein AAA_23 PF13476.6 EOO00652.1 - 0.11 13.0 0.2 0.17 12.4 0.2 1.2 1 0 0 1 1 1 0 AAA domain DUF16 PF01519.16 EOO00652.1 - 0.6 10.6 3.3 7.1 7.2 3.3 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 Uricase PF01014.18 EOO00654.1 - 3.9e-79 263.3 0.4 5.2e-42 143.2 0.4 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.19 EOO00654.1 - 0.14 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme AAR2 PF05282.11 EOO00655.1 - 1.1e-50 173.0 0.0 2.3e-50 172.0 0.0 1.5 1 1 0 1 1 1 1 AAR2 protein Phos_pyr_kin PF08543.12 EOO00656.1 - 2.5e-86 289.1 0.7 6.5e-86 287.7 1.1 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EOO00656.1 - 7.8e-47 159.8 0.0 1.1e-46 159.3 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 EOO00656.1 - 1.3e-06 27.9 0.3 8.2e-06 25.3 0.3 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 EOO00656.1 - 0.069 12.5 2.3 1.3 8.3 0.0 2.8 3 0 0 3 3 3 0 Hydroxyethylthiazole kinase family DnaJ_C PF01556.18 EOO00657.1 - 1.5e-36 125.8 0.1 2.2e-36 125.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EOO00657.1 - 1.5e-22 79.4 2.6 3.1e-22 78.5 2.6 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EOO00657.1 - 2.5e-14 53.4 15.5 4e-14 52.7 15.5 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EOO00657.1 - 0.0064 16.4 12.2 0.14 12.2 2.4 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EOO00657.1 - 0.091 12.8 8.3 2.2 8.3 1.3 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 EOO00657.1 - 0.32 10.6 6.8 4.6 6.9 0.5 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 EOO00657.1 - 0.69 10.0 8.6 2.3 8.3 0.9 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_10 PF16685.5 EOO00657.1 - 0.82 9.9 6.9 8.6 6.6 0.7 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 Cytochrome_C7 PF14522.6 EOO00657.1 - 3.1 7.9 7.7 1.9 8.5 1.7 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c DUF2577 PF10844.8 EOO00658.1 - 0.053 13.7 0.0 3.4 8.0 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2577) Ribosomal_S9 PF00380.19 EOO00659.1 - 5.9e-33 114.0 0.1 6.6e-33 113.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 PAN_1 PF00024.26 EOO00661.1 - 7.4e-05 22.6 0.2 7.4e-05 22.6 0.2 1.8 2 0 0 2 2 2 1 PAN domain CCDC24 PF15669.5 EOO00661.1 - 1.6 8.5 4.8 2.5 7.9 4.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF1180 PF06679.12 EOO00661.1 - 4.4 7.7 7.4 0.39 11.1 2.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Macoilin PF09726.9 EOO00661.1 - 4.8 5.6 5.9 5.7 5.4 5.9 1.1 1 0 0 1 1 1 0 Macoilin family SGL PF08450.12 EOO00662.1 - 5.6e-69 232.5 0.1 8.9e-69 231.8 0.0 1.3 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EOO00662.1 - 0.021 15.0 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 Arylesterase DUF5074 PF16819.5 EOO00662.1 - 0.13 12.3 0.0 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5074) Mpv17_PMP22 PF04117.12 EOO00663.1 - 7.7e-10 38.9 3.4 3.6e-09 36.7 2.5 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family ELFV_dehydrog PF00208.21 EOO00664.1 - 5e-66 222.9 0.0 7.7e-66 222.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EOO00664.1 - 6.1e-17 60.5 0.0 1.9e-12 45.6 0.0 2.3 2 1 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EOO00664.1 - 0.0022 17.9 0.0 0.016 15.1 0.0 2.2 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain PRCC PF10253.9 EOO00665.1 - 3.1e-34 119.7 12.5 1.4e-33 117.6 12.5 2.1 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Alk_phosphatase PF00245.20 EOO00666.1 - 8.3e-101 337.9 0.0 1e-100 337.6 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EOO00666.1 - 3.1e-05 23.5 0.0 5.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily p450 PF00067.22 EOO00667.1 - 1e-43 149.8 0.0 1.3e-43 149.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NPV_P10 PF05531.12 EOO00667.1 - 0.19 12.2 0.0 0.43 11.1 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Methyltransf_PK PF05891.12 EOO00668.1 - 1.2e-84 283.2 0.0 1.4e-84 283.0 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EOO00668.1 - 0.00024 21.7 0.0 0.00044 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO00668.1 - 0.0032 18.1 0.0 0.005 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EOO00668.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain adh_short_C2 PF13561.6 EOO00669.1 - 1.7e-54 184.9 2.2 2.1e-54 184.5 2.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO00669.1 - 5.9e-36 123.8 0.6 9.6e-36 123.1 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO00669.1 - 6.8e-12 45.7 0.7 8.6e-12 45.3 0.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO00669.1 - 0.0022 17.5 0.3 0.0034 16.9 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EOO00669.1 - 0.0036 16.5 0.0 0.0045 16.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EOO00669.1 - 0.0039 16.6 0.0 0.006 16.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EOO00669.1 - 0.026 13.6 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GRP PF07172.11 EOO00670.1 - 0.02 15.6 0.0 0.027 15.2 0.0 1.3 1 0 0 1 1 1 0 Glycine rich protein family LigD_N PF13298.6 EOO00671.1 - 6e-33 113.3 0.0 1.8e-32 111.7 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) EF-hand_1 PF00036.32 EOO00672.1 - 3.1e-38 126.5 10.3 1.2e-08 33.9 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EOO00672.1 - 1.3e-32 112.1 2.6 3.9e-16 59.3 0.3 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EOO00672.1 - 6.3e-30 100.5 3.4 4.8e-08 32.3 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EOO00672.1 - 7.4e-29 99.4 6.7 1.5e-13 50.4 0.6 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EOO00672.1 - 1.9e-23 80.9 8.3 7.5e-08 31.5 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EOO00672.1 - 5.9e-13 48.9 0.1 2.7e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EOO00672.1 - 1.1e-08 35.0 1.0 0.00047 20.1 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EOO00672.1 - 7.5e-07 29.5 0.1 0.034 14.5 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EOO00672.1 - 4.5e-06 27.5 0.0 0.023 15.5 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain Caleosin PF05042.13 EOO00672.1 - 9.3e-05 22.4 0.3 1.9 8.4 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein UPF0154 PF03672.13 EOO00672.1 - 0.0016 18.4 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) TerB PF05099.13 EOO00672.1 - 0.0032 17.4 0.1 2 8.4 0.0 2.1 1 1 1 2 2 2 2 Tellurite resistance protein TerB Dockerin_1 PF00404.18 EOO00672.1 - 0.024 14.8 3.4 6.8 7.0 3.4 3.0 1 1 0 1 1 1 0 Dockerin type I domain DUF892 PF05974.12 EOO00672.1 - 0.025 14.6 0.5 0.65 10.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF892) DUF5580 PF17743.1 EOO00672.1 - 0.027 13.0 0.0 0.086 11.4 0.0 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5580) DED PF01335.21 EOO00672.1 - 0.036 14.4 0.6 0.21 11.9 0.1 2.4 2 1 1 3 3 3 0 Death effector domain Syntaxin PF00804.25 EOO00672.1 - 0.044 13.4 4.0 2.5 7.7 0.6 2.5 2 1 0 2 2 2 0 Syntaxin EF-hand_14 PF17959.1 EOO00672.1 - 0.085 13.2 0.0 7.5 7.0 0.0 2.4 2 1 0 2 2 2 0 EF-hand domain RNA_pol_Rpb4 PF03874.16 EOO00672.1 - 0.18 12.2 1.3 5.3 7.4 0.0 2.3 2 1 0 2 2 2 0 RNA polymerase Rpb4 PX PF00787.24 EOO00673.1 - 4.3e-21 75.0 0.0 6.7e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 PX domain Thioredoxin_4 PF13462.6 EOO00674.1 - 0.00027 21.1 0.0 0.00064 19.9 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin Phage_TAC_6 PF09550.10 EOO00674.1 - 0.09 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC SAS4 PF15460.6 EOO00675.1 - 5.8e-31 106.5 0.1 5.8e-31 106.5 0.1 3.0 3 0 0 3 3 3 1 Something about silencing, SAS, complex subunit 4 SDA1 PF05285.12 EOO00675.1 - 0.026 14.0 29.3 0.06 12.8 29.3 1.6 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EOO00675.1 - 0.16 10.2 28.6 0.26 9.5 28.6 1.2 1 0 0 1 1 1 0 Nop14-like family Pollen_allerg_2 PF01620.16 EOO00675.1 - 0.17 12.0 1.5 0.37 11.0 1.5 1.5 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) Paf1 PF03985.13 EOO00675.1 - 1.1 8.2 24.8 2.9 6.8 24.8 1.8 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 EOO00675.1 - 1.8 6.7 21.1 3.7 5.7 21.1 1.6 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 EOO00675.1 - 2.1 7.7 19.6 7 6.0 19.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4820 PF16091.5 EOO00675.1 - 6.7 6.0 10.1 18 4.6 10.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) AA_permease_2 PF13520.6 EOO00676.1 - 5.2e-41 140.9 46.9 6.3e-41 140.6 46.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EOO00676.1 - 6e-26 91.1 39.4 8.5e-26 90.6 39.4 1.1 1 0 0 1 1 1 1 Amino acid permease Pyr_redox_2 PF07992.14 EOO00677.1 - 6e-09 35.6 0.0 4.3e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EOO00677.1 - 6.9e-05 22.6 0.7 0.0019 17.8 0.2 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EOO00677.1 - 0.00022 21.3 0.1 0.0028 17.7 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EOO00677.1 - 0.00086 18.3 0.1 0.0018 17.2 0.1 1.5 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_8 PF13450.6 EOO00677.1 - 0.0068 16.6 0.0 0.022 15.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EOO00677.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EOO00677.1 - 0.053 12.8 0.1 2.3 7.4 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EOO00677.1 - 0.055 14.0 0.2 0.49 11.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EOO00677.1 - 0.25 10.4 0.3 1.1 8.2 0.3 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EOO00677.1 - 0.8 9.0 2.5 6.2 6.0 0.8 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Rad4 PF03835.15 EOO00678.1 - 2.4e-15 56.5 2.7 5.3e-15 55.4 2.7 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EOO00678.1 - 0.07 13.6 1.0 0.17 12.4 1.0 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily DNA_ligase_ZBD PF03119.16 EOO00678.1 - 4.7 7.3 6.1 48 4.1 6.1 2.5 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Glyco_hydro_3_C PF01915.22 EOO00679.1 - 3.4e-67 226.4 0.0 1.2e-66 224.6 0.0 1.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EOO00679.1 - 3.9e-54 184.2 0.0 6.5e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EOO00679.1 - 5.4e-24 84.1 0.1 1.1e-23 83.1 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EOO00679.1 - 1.8e-23 83.0 0.0 2.9e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 PA14 domain FAD_binding_3 PF01494.19 EOO00681.1 - 3e-22 79.3 0.6 2.4e-21 76.4 0.6 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EOO00681.1 - 3.3e-05 23.3 0.0 0.04 13.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EOO00681.1 - 0.00012 21.5 0.2 0.0036 16.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EOO00681.1 - 0.0027 17.9 0.0 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EOO00681.1 - 0.0031 17.2 0.8 0.0074 15.9 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EOO00681.1 - 0.0099 15.2 0.2 2.2 7.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 EOO00681.1 - 0.026 13.4 1.0 0.059 12.2 0.4 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Sigma70_r3 PF04539.16 EOO00681.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-70 region 3 FAD_binding_2 PF00890.24 EOO00682.1 - 3.5e-83 280.0 0.7 4.4e-83 279.7 0.7 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EOO00682.1 - 1.3e-20 73.3 0.1 7.2e-20 70.9 0.0 2.4 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EOO00682.1 - 8.7e-14 51.9 0.3 1.6e-13 51.0 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EOO00682.1 - 3.7e-09 36.5 0.8 1.3e-08 34.7 0.8 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EOO00682.1 - 6.8e-08 32.6 0.6 5.3e-07 29.8 0.4 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EOO00682.1 - 2.5e-07 30.2 0.3 3.7e-06 26.4 0.2 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EOO00682.1 - 4.5e-06 26.1 0.0 0.042 13.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EOO00682.1 - 3.7e-05 22.6 2.5 0.0074 15.0 0.1 3.2 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 EOO00682.1 - 0.00026 20.3 0.4 0.027 13.7 0.1 2.3 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EOO00682.1 - 0.00036 19.7 1.5 0.09 11.8 0.7 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 EOO00682.1 - 0.0012 18.3 0.8 0.31 10.3 0.2 2.8 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 EOO00682.1 - 0.0032 16.8 1.9 0.0067 15.7 0.9 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EOO00682.1 - 0.032 13.5 0.5 0.058 12.7 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EOO00682.1 - 0.06 13.9 3.0 2.3 8.8 0.7 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase YicC_N PF03755.13 EOO00683.1 - 0.052 14.0 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 YicC-like family, N-terminal region PALP PF00291.25 EOO00684.1 - 7.4e-64 216.0 1.8 8.5e-64 215.8 1.8 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4065 PF13274.6 EOO00685.1 - 4.8 8.1 7.8 1.6 9.6 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) adh_short PF00106.25 EOO00686.1 - 6.2e-32 110.6 0.0 8.6e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO00686.1 - 4.5e-25 88.6 0.0 7.9e-25 87.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO00686.1 - 1.6e-09 37.9 0.0 2.2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EOO00686.1 - 7.3e-08 31.9 0.0 9.8e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EOO00686.1 - 0.00021 20.8 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EOO00686.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 EOO00686.1 - 0.0023 17.3 0.0 0.0058 16.0 0.0 1.6 2 0 0 2 2 2 1 ThiF family 3Beta_HSD PF01073.19 EOO00686.1 - 0.016 14.2 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.8 EOO00686.1 - 0.035 13.8 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.17 EOO00686.1 - 0.047 14.3 0.0 0.12 13.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EOO00686.1 - 0.054 13.7 0.0 0.084 13.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF4579 PF15158.6 EOO00687.1 - 0.19 11.5 4.0 0.072 12.8 1.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4579) Cation_ATPase_C PF00689.21 EOO00687.1 - 10 5.8 19.8 0.92 9.2 1.2 2.5 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus CLZ PF16526.5 EOO00688.1 - 0.063 13.7 0.9 0.063 13.7 0.9 4.6 4 1 0 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels OmpH PF03938.14 EOO00688.1 - 0.067 13.5 28.7 2 8.7 6.3 4.3 2 1 2 4 4 4 0 Outer membrane protein (OmpH-like) THP2 PF09432.10 EOO00688.1 - 0.13 12.3 9.9 0.024 14.7 3.3 2.8 1 1 1 2 2 2 0 Tho complex subunit THP2 PSII_Pbs27 PF13326.6 EOO00688.1 - 0.25 11.7 6.2 1.1 9.6 1.5 3.1 2 1 0 3 3 3 0 Photosystem II Pbs27 ParD_antitoxin PF03693.14 EOO00688.1 - 0.52 10.8 3.2 2.1 8.8 0.2 3.1 3 0 0 3 3 3 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Gp-FAR-1 PF05823.12 EOO00688.1 - 0.7 10.2 5.1 1 9.7 0.6 2.7 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4407 PF14362.6 EOO00688.1 - 1.8 7.9 26.9 17 4.6 10.7 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Terminase_4 PF05119.12 EOO00688.1 - 2.2 8.8 6.7 19 5.8 2.3 3.5 2 1 0 2 2 2 0 Phage terminase, small subunit DUF3365 PF11845.8 EOO00688.1 - 4.6 7.5 4.9 82 3.5 3.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3365) UPF0242 PF06785.11 EOO00688.1 - 5.4 7.1 31.4 11 6.1 13.1 3.1 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus GTP_EFTU PF00009.27 EOO00689.1 - 1.4e-46 158.5 0.0 2.1e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EOO00689.1 - 8.9e-37 126.4 8.6 1.8e-36 125.4 8.6 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EOO00689.1 - 2.6e-24 85.3 0.0 7.4e-24 83.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EOO00689.1 - 1.8e-19 69.5 0.0 5.7e-19 67.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EOO00689.1 - 2.8e-09 37.2 0.0 7.9e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EOO00689.1 - 1.2e-06 28.5 0.0 2.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EOO00689.1 - 2.7e-05 24.2 0.2 5.2e-05 23.3 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MFS_1 PF07690.16 EOO00690.1 - 2e-51 175.0 35.1 2e-51 175.0 35.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO00690.1 - 5.1e-11 42.1 10.3 5.1e-11 42.1 10.3 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EOO00690.1 - 6.3e-06 24.9 3.5 1e-05 24.2 3.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EOO00690.1 - 2.3 6.4 15.5 2.5 6.3 10.4 3.2 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.25 EOO00691.1 - 7.6e-58 195.9 0.0 1e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO00691.1 - 5e-26 91.5 0.0 8.1e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EOO00691.1 - 1.1e-07 31.4 0.0 1.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EOO00691.1 - 0.0036 17.3 0.0 1.1 9.2 0.0 2.8 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EOO00691.1 - 0.008 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GDYXXLXY PF14345.6 EOO00691.1 - 0.097 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 GDYXXLXY protein Aldo_ket_red PF00248.21 EOO00692.1 - 1.9e-39 135.6 0.0 2.5e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Fasciclin PF02469.22 EOO00693.1 - 0.015 15.5 0.0 0.032 14.5 0.0 1.6 1 1 0 1 1 1 0 Fasciclin domain Ribosomal_L31e PF01198.19 EOO00694.1 - 1.8e-40 137.0 0.9 2.3e-40 136.7 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e ATG_C PF09333.11 EOO00695.1 - 0.039 14.3 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EOO00695.1 - 0.12 12.1 0.7 1.8 8.3 0.2 2.0 1 1 1 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal UIM PF02809.20 EOO00695.1 - 1.1 9.3 43.0 0.25 11.3 0.3 6.4 6 0 0 6 6 6 0 Ubiquitin interaction motif SHOCT PF09851.9 EOO00695.1 - 2 8.3 7.0 9.3 6.1 0.3 3.0 2 0 0 2 2 2 0 Short C-terminal domain Peptidase_S8 PF00082.22 EOO00696.1 - 1.3e-35 123.2 0.8 1.9e-35 122.6 0.8 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EOO00696.1 - 5.5e-25 87.2 1.5 1.3e-24 86.0 1.5 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 EOO00696.1 - 0.00059 20.5 0.1 0.0017 19.1 0.1 1.8 1 0 0 1 1 1 1 Peptidase S8 pro-domain Methyltransf_11 PF08241.12 EOO00696.1 - 0.15 12.7 0.0 0.35 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S8_N PF16361.5 EOO00696.1 - 0.16 12.5 1.1 0.26 11.8 0.1 1.9 2 0 0 2 2 2 0 N-terminal of Subtilase family Epimerase PF01370.21 EOO00697.1 - 6.2e-12 45.5 0.0 2.2e-09 37.2 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EOO00697.1 - 4.9e-07 29.8 0.0 7.3e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding XhoI PF04555.13 EOO00697.1 - 0.097 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease XhoI MARVEL PF01284.23 EOO00699.1 - 5.5e-09 36.2 16.9 8e-09 35.7 16.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain TssN PF17555.2 EOO00699.1 - 1.8 7.9 9.5 2.9 7.2 9.5 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN NAD_binding_1 PF00175.21 EOO00701.1 - 5e-33 114.0 0.0 1e-32 113.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EOO00701.1 - 2.8e-24 85.4 0.0 4.5e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EOO00701.1 - 1e-08 35.4 0.0 0.00071 19.7 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain CsbD PF05532.12 EOO00701.1 - 0.0075 16.2 1.6 0.015 15.2 1.6 1.4 1 0 0 1 1 1 1 CsbD-like FAD_binding_9 PF08021.11 EOO00701.1 - 0.024 14.9 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Mito_carr PF00153.27 EOO00702.1 - 1.2e-59 198.2 3.6 1.5e-20 72.9 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EOO00702.1 - 0.18 11.0 0.2 1.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Gammaproteobacterial serine protease IQ PF00612.27 EOO00703.1 - 0.00021 20.8 1.6 0.00064 19.3 1.6 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif SR-25 PF10500.9 EOO00703.1 - 0.0003 20.5 10.0 0.0003 20.5 10.0 4.1 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein NAPRTase PF04095.16 EOO00704.1 - 3e-56 190.8 0.5 6.9e-31 107.7 1.2 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EOO00704.1 - 2.2e-33 115.3 0.0 4.2e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain ABC_trans_N PF14510.6 EOO00704.1 - 0.12 13.0 0.1 0.29 11.8 0.1 1.6 1 0 0 1 1 1 0 ABC-transporter N-terminal Fungal_trans PF04082.18 EOO00705.1 - 4.1e-08 32.6 0.0 5.7e-05 22.3 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EOO00705.1 - 0.004 17.2 7.4 0.0066 16.5 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GET2 PF08690.10 EOO00705.1 - 2.6 7.6 5.1 0.41 10.3 1.3 1.5 2 0 0 2 2 2 0 GET complex subunit GET2 DUF3290 PF11694.8 EOO00706.1 - 0.13 12.3 0.2 0.37 10.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Cyclin_N PF00134.23 EOO00708.1 - 5.1e-40 136.1 0.4 1.2e-39 134.9 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EOO00708.1 - 1.1e-11 44.8 0.2 1.1e-10 41.7 0.2 2.3 1 1 0 1 1 1 1 Cyclin, C-terminal domain Caskin-Pro-rich PF16907.5 EOO00708.1 - 0.086 13.4 1.3 0.11 13.0 0.1 1.7 2 0 0 2 2 2 0 Proline rich region of Caskin proteins Fungal_trans PF04082.18 EOO00709.1 - 7.7e-06 25.1 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1631 PF07793.11 EOO00709.1 - 0.012 14.1 2.8 0.013 14.0 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) ADH_zinc_N PF00107.26 EOO00710.1 - 4.8e-26 91.3 0.1 8.7e-26 90.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EOO00710.1 - 1.4e-06 28.2 0.1 6.1e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EOO00710.1 - 0.00024 22.2 0.0 0.00047 21.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EOO00710.1 - 0.0017 17.9 0.5 0.0027 17.2 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 EOO00710.1 - 0.012 14.9 1.1 0.022 14.1 1.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CMAS PF02353.20 EOO00710.1 - 0.064 12.5 0.1 0.097 11.9 0.1 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ACP_syn_III_C PF08541.10 EOO00710.1 - 0.072 13.3 4.4 0.08 13.1 2.0 2.3 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Eno-Rase_NADH_b PF12242.8 EOO00710.1 - 0.38 10.5 1.9 0.83 9.5 1.4 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ANAPC4_WD40 PF12894.7 EOO00711.1 - 3e-06 27.4 0.1 0.027 14.7 0.0 4.7 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EOO00711.1 - 5.8e-06 26.9 5.8 33 5.6 0.0 8.0 8 1 0 8 8 8 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EOO00711.1 - 0.002 17.1 0.0 0.54 9.2 0.0 3.1 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3807 PF12720.7 EOO00712.1 - 9.8e-54 182.4 10.6 1.1e-53 182.2 10.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) GAGA_bind PF06217.12 EOO00712.1 - 0.00057 20.3 0.9 0.00067 20.0 0.9 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family YL1 PF05764.13 EOO00712.1 - 0.0081 16.3 8.0 0.01 16.0 8.0 1.1 1 0 0 1 1 1 1 YL1 nuclear protein PI3K_1B_p101 PF10486.9 EOO00712.1 - 0.084 10.6 2.7 0.1 10.4 2.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Usp PF00582.26 EOO00712.1 - 0.25 11.8 1.6 0.3 11.6 0.3 1.7 2 0 0 2 2 2 0 Universal stress protein family p450 PF00067.22 EOO00713.1 - 2.4e-76 257.3 0.0 2.8e-76 257.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADK PF00406.22 EOO00714.1 - 7.9e-37 126.7 0.0 2e-20 73.4 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 EOO00714.1 - 1.1e-15 57.2 0.0 2.2e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 EOO00714.1 - 5e-15 56.1 0.0 4.5e-11 43.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EOO00714.1 - 0.00023 21.3 0.0 0.0025 18.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EOO00714.1 - 0.0013 19.3 0.0 0.012 16.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EOO00714.1 - 0.077 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pkinase PF00069.25 EOO00715.1 - 5.7e-65 219.3 0.1 6.7e-65 219.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO00715.1 - 7.9e-19 67.9 0.0 1.1e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EOO00715.1 - 2.4e-08 34.2 0.0 2.9e-06 27.4 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EOO00715.1 - 0.007 15.2 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EOO00715.1 - 0.011 15.0 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EOO00715.1 - 0.025 13.9 0.1 0.045 13.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EOO00715.1 - 0.056 13.0 0.1 0.056 13.0 0.1 2.0 3 0 0 3 3 3 0 Choline/ethanolamine kinase Sec61_beta PF03911.16 EOO00716.1 - 3e-19 68.8 1.9 3.9e-19 68.4 1.9 1.2 1 0 0 1 1 1 1 Sec61beta family DUF1180 PF06679.12 EOO00716.1 - 0.15 12.5 1.9 0.16 12.3 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Transp_cyt_pur PF02133.15 EOO00717.1 - 2.5e-46 158.4 5.4 3e-44 151.5 5.4 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF681 PF05080.12 EOO00717.1 - 0.1 13.3 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF681) DUF4834 PF16118.5 EOO00720.1 - 3.8 8.5 0.0 3.8 8.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Raffinose_syn PF05691.12 EOO00721.1 - 1.5e-56 191.6 3.0 2.1e-46 158.1 0.1 3.1 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 ocr PF08684.10 EOO00721.1 - 0.0019 18.6 0.2 0.01 16.3 0.0 2.3 4 0 0 4 4 4 1 DNA mimic ocr Melibiase PF02065.18 EOO00721.1 - 0.12 11.3 2.2 0.086 11.8 0.6 1.4 2 0 0 2 2 2 0 Melibiase Ssu72 PF04722.13 EOO00722.1 - 8e-75 250.6 0.0 9e-75 250.4 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein NUP PF06516.11 EOO00723.1 - 1.1e-137 458.5 0.2 1.2e-137 458.3 0.2 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Ribonuc_L-PSP PF01042.21 EOO00724.1 - 1.4e-18 67.0 0.0 1.6e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP GGACT PF06094.12 EOO00725.1 - 1.3e-09 38.7 0.1 2.8e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like SpoIIE PF07228.12 EOO00725.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) F-box-like PF12937.7 EOO00726.1 - 7.9e-11 41.7 0.1 1.6e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EOO00726.1 - 0.00017 21.4 0.0 0.00042 20.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain Glyco_hydro_31 PF01055.26 EOO00727.1 - 1.3e-142 476.1 0.9 1.7e-142 475.7 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EOO00727.1 - 1.2e-31 109.3 0.0 2e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Rotavirus_VP7 PF05868.11 EOO00727.1 - 0.15 11.4 0.1 0.31 10.4 0.1 1.4 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 Spc7 PF08317.11 EOO00728.1 - 1.6e-86 290.0 15.2 1.9e-86 289.8 15.2 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 EOO00728.1 - 0.0056 16.3 2.7 0.0063 16.1 2.7 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF3348 PF11828.8 EOO00728.1 - 0.0093 15.7 4.1 0.011 15.5 3.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3348) Spc29 PF17082.5 EOO00728.1 - 0.011 15.6 1.4 0.011 15.6 1.4 2.3 1 1 1 2 2 2 0 Spindle Pole Component 29 APG6_N PF17675.1 EOO00728.1 - 0.016 15.8 13.7 0.016 15.8 13.7 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region TALPID3 PF15324.6 EOO00728.1 - 0.027 12.2 2.1 0.036 11.8 2.1 1.1 1 0 0 1 1 1 0 Hedgehog signalling target MT PF12777.7 EOO00728.1 - 0.03 13.4 3.0 0.045 12.8 3.0 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Laminin_II PF06009.12 EOO00728.1 - 0.036 14.1 6.3 2.4 8.2 0.1 2.4 2 0 0 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.9 EOO00728.1 - 0.1 12.9 6.5 2.8 8.3 3.4 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 EOO00728.1 - 0.35 10.2 2.6 0.53 9.6 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) STAT_alpha PF01017.20 EOO00728.1 - 0.4 10.6 8.2 0.45 10.4 1.7 2.5 1 1 1 2 2 2 0 STAT protein, all-alpha domain DUF4200 PF13863.6 EOO00728.1 - 0.45 10.9 13.5 1.2 9.5 13.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Prefoldin_2 PF01920.20 EOO00728.1 - 0.76 9.8 12.8 0.39 10.7 3.9 3.4 1 1 2 3 3 3 0 Prefoldin subunit RPAP1_N PF08621.10 EOO00728.1 - 1.2 9.0 8.5 4.8 7.0 0.2 3.0 3 0 0 3 3 2 0 RPAP1-like, N-terminal GAS PF13851.6 EOO00728.1 - 1.4 8.3 15.1 0.96 8.8 11.0 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 EOO00728.1 - 1.8 8.6 20.8 1.8 8.6 16.5 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 EOO00728.1 - 6.1 6.9 16.6 2.6 8.1 9.1 2.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein 7TMR-HDED PF07697.11 EOO00728.1 - 7.9 6.5 8.6 5.4 7.1 5.7 1.9 1 1 1 2 2 2 0 7TM-HD extracellular PVL_ORF50 PF07768.11 EOO00728.1 - 8.9 6.7 9.1 19 5.6 1.0 2.5 1 1 1 2 2 2 0 PVL ORF-50-like family Pneumo_att_G PF05539.11 EOO00729.1 - 0.078 12.6 31.5 0.11 12.0 31.5 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SOG2 PF10428.9 EOO00729.1 - 1.5 7.9 21.4 2 7.5 21.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Pheromone PF08015.11 EOO00729.1 - 3.5 8.8 13.3 31 5.7 12.8 2.6 1 1 0 1 1 1 0 Fungal mating-type pheromone Red1 PF07964.11 EOO00729.1 - 3.8 5.6 18.3 4.6 5.4 18.3 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Ndc1_Nup PF09531.10 EOO00729.1 - 3.8 6.1 14.8 4.5 5.8 14.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SAPS PF04499.15 EOO00729.1 - 6.1 5.5 6.8 7.8 5.1 6.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Macoilin PF09726.9 EOO00729.1 - 9.7 4.6 15.4 11 4.4 15.4 1.1 1 0 0 1 1 1 0 Macoilin family GDPD PF03009.17 EOO00730.1 - 1.5e-11 44.5 0.0 2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Cep57_MT_bd PF06657.13 EOO00731.1 - 6e-26 90.7 0.1 6e-26 90.7 0.1 5.0 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 EOO00731.1 - 6.8e-11 42.1 6.9 6.8e-11 42.1 6.9 5.9 3 1 4 7 7 7 1 Centrosome localisation domain of PPC89 KASH_CCD PF14662.6 EOO00731.1 - 0.0041 17.0 23.5 0.0041 17.0 23.5 4.6 3 1 2 5 5 5 3 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 EOO00731.1 - 0.014 15.9 12.2 0.014 15.9 12.2 5.8 4 1 3 7 7 7 0 Apg6 coiled-coil region RTBV_P46 PF06216.11 EOO00731.1 - 0.021 13.8 6.1 0.084 11.7 0.6 2.3 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein OstA PF03968.14 EOO00731.1 - 0.13 12.5 1.5 0.76 10.0 0.4 2.7 2 0 0 2 2 2 0 OstA-like protein Cnn_1N PF07989.11 EOO00731.1 - 1.5 9.0 40.0 1.6 8.9 2.7 6.0 4 1 1 5 5 5 0 Centrosomin N-terminal motif 1 Scaffolding_pro PF11418.8 EOO00731.1 - 3.4 8.3 15.2 2.9 8.5 1.3 4.3 2 1 2 4 4 4 0 Phi29 scaffolding protein adh_short_C2 PF13561.6 EOO00732.1 - 9.1e-54 182.5 0.2 1.1e-53 182.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO00732.1 - 8.2e-46 155.9 0.2 1e-45 155.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO00732.1 - 1.1e-07 32.0 0.0 1.4e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO00732.1 - 0.0014 18.2 0.2 0.0021 17.5 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Mitochondr_Som1 PF11093.8 EOO00733.1 - 0.012 15.6 0.1 0.033 14.2 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial export protein Som1 adh_short_C2 PF13561.6 EOO00734.1 - 7.2e-58 195.9 0.3 1.2e-57 195.2 0.3 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO00734.1 - 2e-44 151.4 2.0 4.4e-44 150.3 2.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO00734.1 - 2.2e-10 40.7 0.6 3.8e-10 40.0 0.6 1.3 1 0 0 1 1 1 1 KR domain DUF4448 PF14610.6 EOO00735.1 - 1.4e-50 171.7 0.1 1.9e-50 171.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.9 EOO00735.1 - 0.0056 17.4 2.8 0.42 11.4 0.4 3.1 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glu_cyclase_2 PF05096.12 EOO00736.1 - 0.23 10.8 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Glutamine cyclotransferase PX PF00787.24 EOO00737.1 - 1.4e-21 76.6 0.1 3.5e-21 75.3 0.1 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EOO00737.1 - 2.6e-11 43.5 9.3 3.9e-06 26.6 1.2 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 EOO00737.1 - 0.00034 20.3 5.9 0.0032 17.1 2.3 2.4 2 0 0 2 2 2 1 BAR domain DUF3140 PF11338.8 EOO00737.1 - 0.01 16.2 0.2 0.052 14.0 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Sec34 PF04136.15 EOO00737.1 - 0.045 13.6 0.1 0.12 12.3 0.1 1.8 1 1 0 1 1 1 0 Sec34-like family AlkA_N PF06029.11 EOO00737.1 - 0.056 13.7 0.2 0.25 11.6 0.1 2.1 2 0 0 2 2 2 0 AlkA N-terminal domain Importin_rep_4 PF18808.1 EOO00737.1 - 0.1 12.9 0.8 2.5 8.4 0.1 2.6 2 0 0 2 2 2 0 Importin repeat DUF1664 PF07889.12 EOO00737.1 - 0.5 10.4 4.0 15 5.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 EOO00737.1 - 1.7 9.1 4.1 16 6.0 0.4 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 EOO00737.1 - 2.1 8.4 9.2 3 7.9 0.2 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Occludin_ELL PF07303.13 EOO00737.1 - 3.2 8.5 5.4 4 8.2 0.0 3.4 3 1 0 4 4 4 0 Occludin homology domain eIF3_subunit PF08597.10 EOO00737.1 - 4.4 7.1 12.2 0.076 12.9 3.0 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Sugar_tr PF00083.24 EOO00738.1 - 3e-113 379.1 15.8 9.4e-111 370.8 15.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO00738.1 - 3.7e-23 82.0 27.3 1.3e-15 57.2 4.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Ilm1 PF10311.9 EOO00738.1 - 0.024 14.3 1.7 0.041 13.5 1.7 1.3 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 DUF1708 PF08101.11 EOO00740.1 - 1.7e-178 594.2 0.0 2.6e-178 593.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) SVIP PF15811.5 EOO00740.1 - 2.3 8.7 11.3 14 6.2 1.6 3.1 2 0 0 2 2 2 0 Small VCP/p97-interacting protein p450 PF00067.22 EOO00741.1 - 1.4e-55 188.9 0.0 2e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro2_C5 PF18565.1 EOO00741.1 - 4e-34 116.5 0.4 8e-34 115.6 0.4 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 EOO00741.1 - 2.3e-27 95.9 0.0 6.3e-27 94.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 EOO00741.1 - 5e-24 84.0 0.4 1.1e-23 82.9 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro_2_N PF02837.18 EOO00741.1 - 2.2e-17 63.5 0.8 5.3e-17 62.2 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 EOO00741.1 - 4.8e-15 56.2 0.0 1.1e-14 55.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 EOO00741.1 - 9.8e-06 26.1 1.2 0.00036 21.1 0.1 2.7 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Invasin_D3 PF09134.10 EOO00741.1 - 7.6e-05 22.9 8.5 0.0011 19.2 2.6 3.3 3 0 0 3 3 3 1 Invasin, domain 3 Cas_NE0113 PF09623.10 EOO00741.1 - 0.035 13.8 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) Big_1 PF02369.16 EOO00741.1 - 0.34 10.9 5.0 0.094 12.7 0.7 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) tRNA-synt_2c PF01411.19 EOO00742.1 - 8.2e-211 701.3 0.1 8.2e-211 701.3 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EOO00742.1 - 2.2e-17 62.8 0.3 5e-17 61.7 0.3 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EOO00742.1 - 7.4e-13 49.1 0.7 2.2e-12 47.6 0.7 1.9 1 0 0 1 1 1 1 DHHA1 domain Sin3a_C PF16879.5 EOO00743.1 - 1.3e-73 248.3 3.4 3.4e-73 246.9 2.2 2.3 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 EOO00743.1 - 1.3e-40 137.3 6.2 4.4e-18 65.2 0.0 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EOO00743.1 - 5.2e-39 132.3 0.0 1.7e-38 130.6 0.0 2.0 1 0 0 1 1 1 1 Sin3 family co-repressor Pollen_allerg_1 PF01357.21 EOO00743.1 - 0.028 14.4 1.8 0.3 11.1 0.3 3.0 3 0 0 3 3 3 0 Pollen allergen Peptidase_S8 PF00082.22 EOO00744.1 - 2e-48 165.2 1.0 3.4e-48 164.4 1.0 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EOO00744.1 - 4.8e-06 27.2 0.0 1.1e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 EOO00744.1 - 0.023 14.7 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 PA domain Peptidase_M1_N PF17900.1 EOO00745.1 - 0.00011 22.5 0.0 0.39 10.9 0.0 2.5 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 EOO00745.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M1 domain TFIIE-A_C PF11521.8 EOO00745.1 - 0.17 12.2 1.7 2.7 8.4 1.1 2.8 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha IMPDH PF00478.25 EOO00746.1 - 6.7e-128 426.5 3.1 7.8e-128 426.3 3.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EOO00746.1 - 9.1e-15 54.9 0.1 1.1e-06 29.0 0.1 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 EOO00746.1 - 5.2e-09 35.6 1.1 2.5e-07 30.1 0.6 2.4 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 EOO00746.1 - 2.8e-08 33.5 4.0 0.0033 16.9 4.2 2.6 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 EOO00746.1 - 0.00056 19.4 5.3 21 4.5 0.1 2.9 2 1 0 2 2 2 1 Histidine biosynthesis protein YpsA PF06908.11 EOO00746.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family PK PF00224.21 EOO00746.1 - 0.028 13.3 0.0 0.093 11.6 0.0 1.7 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain ThiG PF05690.14 EOO00746.1 - 0.069 12.4 3.0 0.11 11.7 0.5 2.6 5 0 0 5 5 5 0 Thiazole biosynthesis protein ThiG WD40 PF00400.32 EOO00747.1 - 3.6e-06 27.6 0.0 0.0053 17.6 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO00747.1 - 0.14 12.5 0.0 5 7.5 0.0 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain adh_short PF00106.25 EOO00748.1 - 1.9e-27 96.0 0.0 2.4e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO00748.1 - 2.9e-23 82.7 0.0 3.7e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO00748.1 - 4.1e-08 33.4 0.0 4.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Metallophos PF00149.28 EOO00749.1 - 6.8e-09 36.5 2.4 2.7e-08 34.5 2.4 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_43 PF04616.14 EOO00750.1 - 1e-52 179.2 0.8 1.3e-52 178.9 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EOO00750.1 - 0.00017 21.4 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain HD_assoc PF13286.6 EOO00751.1 - 0.0072 16.8 0.2 0.084 13.4 0.0 2.7 3 0 0 3 3 3 1 Phosphohydrolase-associated domain DUF1656 PF07869.12 EOO00751.1 - 0.23 11.5 2.2 0.41 10.7 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) DUF488 PF04343.13 EOO00752.1 - 0.2 12.3 3.0 0.34 11.5 1.2 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF488 Ldh_2 PF02615.14 EOO00753.1 - 1e-95 320.7 0.0 1.2e-95 320.5 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase ADH_zinc_N PF00107.26 EOO00754.1 - 2.3e-21 76.1 0.2 4.4e-21 75.2 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EOO00754.1 - 1.5e-17 63.5 1.0 2.5e-17 62.7 0.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EOO00754.1 - 5e-05 22.7 0.0 9.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EOO00754.1 - 9e-05 21.9 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 EOO00754.1 - 0.018 15.7 0.1 0.049 14.3 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.18 EOO00754.1 - 0.021 15.1 0.1 0.056 13.7 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EOO00754.1 - 0.032 14.1 0.1 0.055 13.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CMAS PF02353.20 EOO00754.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Peptidase_S37 PF05576.11 EOO00754.1 - 0.19 10.3 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 PS-10 peptidase S37 Sel1 PF08238.12 EOO00755.1 - 5.1e-40 135.0 38.0 8.4e-06 26.3 0.4 12.8 11 1 0 11 11 11 10 Sel1 repeat TPR_17 PF13431.6 EOO00755.1 - 0.0048 17.2 5.4 37 5.0 0.1 6.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EOO00755.1 - 0.0098 16.5 16.5 3.8 8.3 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EOO00755.1 - 0.015 15.3 3.5 4.2 7.6 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2615 PF11027.8 EOO00755.1 - 0.04 14.0 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) FeS_assembly_P PF01883.19 EOO00756.1 - 3e-07 30.5 0.0 1.4e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Peptidase_S9 PF00326.21 EOO00757.1 - 1.4e-08 34.4 0.0 0.00011 21.8 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EOO00757.1 - 1.8e-07 31.2 0.0 2.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EOO00757.1 - 0.00063 19.4 0.0 0.00091 18.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EOO00757.1 - 0.034 13.4 0.0 0.99 8.6 0.0 2.2 2 1 0 2 2 2 0 Serine aminopeptidase, S33 AXE1 PF05448.12 EOO00757.1 - 0.093 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) HTH_28 PF13518.6 EOO00758.1 - 0.15 12.2 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MFS_1 PF07690.16 EOO00759.1 - 4.3e-34 118.0 39.1 4.3e-34 118.0 39.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PK PF00224.21 EOO00760.1 - 1.5e-171 570.0 6.7 1.9e-171 569.6 6.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EOO00760.1 - 6.5e-37 126.3 0.0 1.8e-36 124.9 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EOO00760.1 - 0.00099 18.3 0.7 0.0058 15.8 0.6 2.1 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family PhoD PF09423.10 EOO00761.1 - 0.0058 15.7 0.0 0.018 14.1 0.0 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase ANAPC4_WD40 PF12894.7 EOO00762.1 - 1.5e-07 31.6 0.0 0.0011 19.3 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EOO00762.1 - 0.00072 19.2 0.3 0.18 11.3 0.0 2.8 1 1 1 2 2 2 2 PQQ-like domain Prothymosin PF03247.14 EOO00762.1 - 0.0018 18.7 11.8 0.0042 17.5 11.8 1.5 1 0 0 1 1 1 1 Prothymosin/parathymosin family WD40 PF00400.32 EOO00762.1 - 0.039 14.8 11.1 2.4 9.1 0.0 4.6 6 1 0 6 6 6 0 WD domain, G-beta repeat PQQ_3 PF13570.6 EOO00762.1 - 0.1 13.1 3.4 15 6.2 0.1 3.9 4 0 0 4 4 4 0 PQQ-like domain CDC45 PF02724.14 EOO00762.1 - 1.6 7.0 6.7 2.1 6.6 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EOO00762.1 - 2.2 6.4 5.7 3 6.0 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family DTHCT PF08070.11 EOO00762.1 - 4.9 7.9 12.8 0.55 11.0 7.6 1.9 2 0 0 2 2 2 0 DTHCT (NUC029) region LicD PF04991.13 EOO00763.1 - 3e-22 79.9 7.4 1.8e-15 57.7 5.5 2.2 1 1 1 2 2 2 2 LicD family Fungal_trans_2 PF11951.8 EOO00764.1 - 0.061 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain AAA PF00004.29 EOO00765.1 - 1.5e-13 51.3 0.0 3.5e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EOO00765.1 - 0.0014 19.0 0.2 0.0032 17.8 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EOO00765.1 - 0.024 14.9 0.3 0.19 12.0 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 EOO00765.1 - 0.035 14.2 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) CPT PF07931.12 EOO00765.1 - 0.066 13.1 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_5 PF07728.14 EOO00765.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PBP1_TM PF14812.6 EOO00765.1 - 2.7 8.4 9.4 44 4.5 4.7 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ANAPC_CDC26 PF10471.9 EOO00766.1 - 4.5e-18 65.9 0.2 4.5e-18 65.9 0.2 3.1 1 1 1 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 MAP65_ASE1 PF03999.12 EOO00766.1 - 0.14 10.8 0.7 0.17 10.5 0.7 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Basic PF01586.16 EOO00766.1 - 0.38 11.9 0.2 0.38 11.9 0.2 2.1 3 0 0 3 3 3 0 Myogenic Basic domain tRNA-synt_2 PF00152.20 EOO00767.1 - 5.1e-40 137.5 0.0 6e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Rad1 PF02144.16 EOO00768.1 - 7.7e-76 254.8 0.0 9.7e-76 254.4 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ost5 PF05251.12 EOO00768.1 - 5.1e-09 36.3 4.8 9.9e-09 35.3 4.8 1.5 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 AMP-binding PF00501.28 EOO00769.1 - 1.7e-89 300.4 0.0 2.2e-89 300.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EOO00769.1 - 8e-11 42.8 0.3 2.1e-10 41.4 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AAA_2 PF07724.14 EOO00769.1 - 0.2 11.7 0.1 0.32 11.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Xan_ur_permease PF00860.20 EOO00770.1 - 2.9e-67 227.1 35.2 5.5e-66 222.9 35.2 2.1 1 1 0 1 1 1 1 Permease family MFS_1 PF07690.16 EOO00771.1 - 1.2e-34 119.8 26.2 1.8e-34 119.3 26.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily BTB PF00651.31 EOO00772.1 - 0.0095 16.2 0.3 0.047 13.9 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain TFR_dimer PF04253.15 EOO00773.1 - 2.6e-30 105.0 0.0 5.7e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EOO00773.1 - 1.1e-20 74.1 0.0 1.9e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EOO00773.1 - 2.2e-09 37.2 1.0 8.4e-09 35.3 0.1 2.2 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.15 EOO00773.1 - 0.048 13.1 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Nicastrin TFIIS_M PF07500.14 EOO00774.1 - 1.1e-26 93.5 0.9 2.1e-26 92.6 0.9 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EOO00774.1 - 2.9e-18 65.4 5.0 4.4e-18 64.8 5.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EOO00774.1 - 1.2e-12 47.7 0.1 3.1e-12 46.3 0.1 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-ZPR1 PF03367.13 EOO00774.1 - 0.0005 20.0 3.1 0.2 11.5 0.6 3.2 3 0 0 3 3 3 2 ZPR1 zinc-finger domain SPT2 PF08243.11 EOO00774.1 - 0.02 15.4 2.0 0.038 14.5 2.0 1.4 1 0 0 1 1 1 0 SPT2 chromatin protein DUF3943 PF13084.6 EOO00774.1 - 0.16 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) NIF PF03031.18 EOO00775.1 - 5.9e-42 143.1 0.5 4.1e-22 78.6 0.1 2.0 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase DUF2608 PF11019.8 EOO00775.1 - 0.06 12.8 0.1 6 6.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) CS PF04969.16 EOO00776.1 - 5.1e-18 65.9 0.3 1.1e-17 64.8 0.1 1.7 2 0 0 2 2 2 1 CS domain RGS PF00615.19 EOO00778.1 - 1.2e-11 45.0 0.0 2.5e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Claudin_2 PF13903.6 EOO00778.1 - 5.8 6.6 5.9 0.66 9.7 0.9 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction MFS_1 PF07690.16 EOO00779.1 - 1.8e-36 125.8 75.4 4.9e-36 124.4 70.1 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EOO00779.1 - 7.6e-13 47.7 31.8 2.6e-12 46.0 31.8 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EOO00779.1 - 5.8e-12 45.2 16.3 5.8e-12 45.2 16.3 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO00780.1 - 1e-09 37.8 13.7 4.1e-05 22.7 9.3 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Rhomboid PF01694.22 EOO00780.1 - 0.16 12.0 4.4 0.11 12.5 2.5 1.8 2 0 0 2 2 2 0 Rhomboid family Ank_2 PF12796.7 EOO00781.1 - 3.2e-12 46.8 0.0 2.2e-06 28.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EOO00781.1 - 2e-09 37.8 0.0 0.00078 20.0 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EOO00781.1 - 6.1e-08 32.3 0.1 0.21 12.2 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EOO00781.1 - 7.1e-07 29.4 0.2 0.13 12.6 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EOO00781.1 - 0.00038 20.8 0.0 15 6.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Peptidase_M6 PF05547.11 EOO00782.1 - 5.5e-22 77.9 3.0 6.2e-21 74.4 3.0 2.4 1 1 0 1 1 1 1 Immune inhibitor A peptidase M6 CaiF_GrlA PF07180.11 EOO00782.1 - 0.25 11.3 0.4 0.51 10.3 0.1 1.6 2 0 0 2 2 2 0 CaiF/GrlA transcriptional regulator DUF1713 PF08213.11 EOO00783.1 - 5.7e-10 38.9 19.5 9.8e-10 38.2 19.5 1.4 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) ER_lumen_recept PF00810.18 EOO00784.1 - 3.5e-41 141.4 6.5 5.5e-41 140.8 6.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EOO00784.1 - 0.22 11.3 0.0 0.22 11.3 0.0 2.8 4 0 0 4 4 4 0 PQ loop repeat adh_short PF00106.25 EOO00785.1 - 2.7e-25 89.0 0.2 3e-25 88.8 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO00785.1 - 2e-24 86.5 0.2 2.2e-24 86.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO00785.1 - 1.1e-08 35.2 0.1 1.4e-08 34.9 0.1 1.0 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EOO00785.1 - 0.00017 20.9 0.0 0.00022 20.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 EOO00785.1 - 0.019 15.1 0.0 0.033 14.3 0.0 1.5 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.21 EOO00785.1 - 0.079 12.3 0.6 0.72 9.2 0.1 2.0 1 1 1 2 2 2 0 ThiF family LRR_4 PF12799.7 EOO00786.1 - 4.1e-35 119.2 22.0 1.7e-08 34.6 0.5 6.9 2 2 6 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EOO00786.1 - 1.8e-22 78.8 21.0 7e-08 32.1 3.2 5.7 2 2 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 EOO00786.1 - 6.3e-16 58.4 9.4 6.3e-10 38.8 0.7 4.0 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 EOO00786.1 - 2e-06 27.4 15.2 0.19 11.9 0.1 8.0 10 0 0 10 10 10 2 Leucine Rich repeat LRR_1 PF00560.33 EOO00786.1 - 3.7e-05 23.7 14.4 22 6.1 0.2 8.7 9 1 0 9 9 9 1 Leucine Rich Repeat p450 PF00067.22 EOO00787.1 - 9.4e-31 107.1 0.0 1.2e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 AP_endonuc_2 PF01261.24 EOO00788.1 - 7.3e-35 120.3 0.3 1.2e-34 119.6 0.3 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel UQ_con PF00179.26 EOO00789.1 - 7.1e-49 165.1 0.0 8.9e-49 164.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EOO00789.1 - 5.4e-06 26.1 0.0 7.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EOO00789.1 - 0.0011 19.2 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 EOO00789.1 - 0.011 15.5 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain PCI PF01399.27 EOO00790.1 - 0.00011 22.7 0.0 0.00015 22.2 0.0 1.2 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 EOO00790.1 - 0.021 14.7 0.1 0.034 14.0 0.1 1.3 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain DinB_2 PF12867.7 EOO00790.1 - 0.096 13.2 2.0 0.27 11.8 1.9 2.0 1 1 0 1 1 1 0 DinB superfamily YhzD PF14120.6 EOO00790.1 - 0.3 11.2 2.4 0.24 11.6 0.3 1.9 2 0 0 2 2 2 0 YhzD-like protein Cellulase PF00150.18 EOO00791.1 - 2.7e-21 76.2 1.4 4e-21 75.7 1.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 EOO00791.1 - 1e-13 51.0 14.2 1e-13 51.0 14.2 3.4 3 0 0 3 3 3 1 Fungal cellulose binding domain DUF4038 PF13204.6 EOO00791.1 - 0.00011 22.0 0.4 0.00016 21.4 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_2_C PF02836.17 EOO00791.1 - 0.00016 20.9 0.2 0.00027 20.1 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 EOO00791.1 - 0.00047 19.6 0.2 0.0011 18.3 0.2 1.6 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_10 PF00331.20 EOO00791.1 - 0.13 11.4 2.3 0.16 11.1 0.1 2.1 3 0 0 3 3 3 0 Glycosyl hydrolase family 10 HPHLAWLY PF14925.6 EOO00791.1 - 2.1 6.9 13.7 3 6.4 13.7 1.1 1 0 0 1 1 1 0 Domain of unknown function UPF0113 PF03657.13 EOO00792.1 - 0.041 14.2 0.1 5.6 7.3 0.0 2.2 2 0 0 2 2 2 0 UPF0113 PUA domain FRG1 PF06229.12 EOO00793.1 - 4.1e-45 153.8 0.4 4.1e-45 153.8 0.4 1.5 2 0 0 2 2 2 1 FRG1-like domain LEA_2 PF03168.13 EOO00793.1 - 0.026 15.1 0.1 0.054 14.0 0.1 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein Frataxin_Cyay PF01491.16 EOO00793.1 - 0.12 12.4 0.0 0.62 10.2 0.0 2.1 2 0 0 2 2 2 0 Frataxin-like domain ABC_membrane_2 PF06472.15 EOO00794.1 - 2.8e-93 312.2 0.3 8.1e-92 307.4 0.0 2.4 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EOO00794.1 - 3.5e-16 60.0 0.0 7.7e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EOO00794.1 - 0.0063 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EOO00794.1 - 0.022 15.3 6.4 0.6 10.6 6.4 2.5 1 1 0 1 1 1 0 AAA domain End3 PF12761.7 EOO00794.1 - 0.025 14.7 0.7 0.086 13.0 0.8 1.8 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Mg_chelatase PF01078.21 EOO00794.1 - 0.04 13.3 0.1 0.07 12.5 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF498 PF04430.14 EOO00794.1 - 0.042 13.9 0.0 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) AAA_29 PF13555.6 EOO00794.1 - 0.065 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.12 EOO00794.1 - 0.085 12.6 0.0 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EOO00794.1 - 0.14 12.6 0.9 0.24 11.8 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 EOO00794.1 - 0.19 12.1 0.0 0.78 10.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Asp PF00026.23 EOO00795.1 - 4.2e-39 134.8 7.9 5.8e-39 134.4 7.9 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EOO00795.1 - 2.3e-05 24.7 0.6 0.00011 22.4 0.1 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal BRX PF08381.11 EOO00795.1 - 0.05 13.0 1.3 0.096 12.1 1.3 1.4 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 WSC PF01822.19 EOO00796.1 - 1.1e-32 112.0 36.3 2.2e-16 59.8 13.7 2.7 2 0 0 2 2 2 2 WSC domain ASH PF15780.5 EOO00796.1 - 0.005 17.0 0.4 0.063 13.5 0.3 2.6 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 EOO00796.1 - 0.14 12.2 1.9 12 6.0 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1573) PQQ_3 PF13570.6 EOO00796.1 - 5 7.8 10.4 3.9 8.1 0.1 4.7 5 0 0 5 5 5 0 PQQ-like domain FMO-like PF00743.19 EOO00797.1 - 1.9e-17 62.9 0.0 2.8e-16 59.1 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EOO00797.1 - 2.8e-10 40.3 0.0 7.8e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EOO00797.1 - 2e-08 33.8 0.0 6.1e-06 25.7 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EOO00797.1 - 5e-06 25.9 0.0 0.0057 15.9 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EOO00797.1 - 1.8e-05 24.1 0.0 0.00051 19.3 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EOO00797.1 - 0.0013 18.8 0.1 0.28 11.2 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 EOO00797.1 - 0.033 13.5 0.0 0.44 9.8 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 EOO00797.1 - 0.047 12.9 0.0 8.8 5.5 0.0 2.4 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 EOO00797.1 - 0.052 13.1 0.0 46 3.4 0.0 3.0 2 1 0 3 3 3 0 FAD dependent oxidoreductase Lipase_GDSL_2 PF13472.6 EOO00798.1 - 5.1e-12 46.6 0.9 6.4e-12 46.2 0.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EOO00798.1 - 1.9e-06 28.0 0.3 3.1e-06 27.3 0.3 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 EOO00798.1 - 0.01 15.6 0.2 0.017 14.8 0.2 1.3 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX MAT1 PF06391.13 EOO00799.1 - 1.8e-37 129.2 9.9 2.3e-37 128.8 9.9 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EOO00799.1 - 1.7e-30 104.7 10.9 2.5e-30 104.1 10.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EOO00799.1 - 0.00092 19.0 5.8 0.0014 18.4 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EOO00799.1 - 0.00099 18.9 5.1 0.0024 17.7 5.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) eIF-3_zeta PF05091.12 EOO00799.1 - 0.0047 16.0 4.1 0.0058 15.7 4.1 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) zf-RING_2 PF13639.6 EOO00799.1 - 0.012 15.9 6.7 0.02 15.2 6.7 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 EOO00799.1 - 0.02 14.8 6.7 0.061 13.2 6.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EOO00799.1 - 0.03 14.0 1.7 0.055 13.1 1.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EOO00799.1 - 0.033 14.1 9.4 0.8 9.7 10.2 2.2 1 1 1 2 2 2 0 zinc-RING finger domain CSRNP_N PF16019.5 EOO00799.1 - 0.36 10.7 9.6 0.71 9.8 9.6 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus zf-RING_UBOX PF13445.6 EOO00799.1 - 0.5 10.4 6.7 1 9.5 6.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger PV-1 PF06637.11 EOO00799.1 - 0.92 8.3 9.4 1.2 7.9 9.4 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) zf-RING_4 PF14570.6 EOO00799.1 - 1.1 9.0 10.5 23 4.9 11.7 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 EOO00799.1 - 1.4 9.0 4.3 4.5 7.5 4.3 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_6 PF14835.6 EOO00799.1 - 2.3 8.2 4.4 3.5 7.6 1.4 2.4 1 1 1 2 2 2 0 zf-RING of BARD1-type protein MRP-S26 PF14943.6 EOO00799.1 - 2.4 8.0 22.4 0.28 11.1 17.8 1.7 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 Presenilin PF01080.17 EOO00799.1 - 9.7 4.8 7.0 12 4.5 7.0 1.1 1 0 0 1 1 1 0 Presenilin OPT PF03169.15 EOO00800.1 - 7.2e-136 454.3 43.5 8.3e-136 454.1 43.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GMC_oxred_N PF00732.19 EOO00801.1 - 1.1e-41 143.2 0.0 1.3e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EOO00801.1 - 1.7e-31 109.7 0.0 3.5e-31 108.7 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase FTA2 PF13095.6 EOO00802.1 - 1.9e-70 236.8 0.0 2.7e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 MARVEL PF01284.23 EOO00803.1 - 3.5e-20 72.5 19.9 4.3e-20 72.2 19.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain Sugar_tr PF00083.24 EOO00804.1 - 5.8e-62 210.0 27.6 6.3e-34 117.6 12.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO00804.1 - 4.8e-20 71.8 29.9 3.8e-17 62.2 6.3 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EOO00804.1 - 0.00016 20.3 1.0 0.00027 19.5 1.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1129 PF06570.11 EOO00804.1 - 4 6.9 9.3 0.084 12.4 1.4 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Aldo_ket_red PF00248.21 EOO00805.1 - 2e-28 99.4 0.0 2.6e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_18 PF00704.28 EOO00806.1 - 1.1e-63 215.9 0.1 1.3e-63 215.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF2796 PF10986.8 EOO00806.1 - 0.22 11.5 0.0 0.73 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) CDP-OH_P_transf PF01066.21 EOO00807.1 - 1.3e-16 61.1 0.5 1.3e-16 61.1 0.5 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase OppC_N PF12911.7 EOO00807.1 - 2.3 8.3 5.9 2.8 8.0 1.8 3.0 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Spt5-NGN PF03439.13 EOO00808.1 - 5.5e-26 90.3 0.0 9.9e-26 89.5 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 EOO00808.1 - 2.5e-20 73.3 9.3 2.5e-20 73.3 9.3 4.4 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 EOO00808.1 - 8e-06 25.6 5.3 4.7e-05 23.2 0.6 5.6 7 0 0 7 7 7 2 KOW motif CTD PF12815.7 EOO00808.1 - 0.0016 19.0 1.5 0.0045 17.5 1.5 1.7 1 0 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF3912 PF13051.6 EOO00808.1 - 0.0073 16.6 0.5 0.038 14.2 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3912) adh_short PF00106.25 EOO00809.1 - 6.9e-48 162.7 0.1 9.1e-48 162.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO00809.1 - 4.7e-45 154.0 0.0 6.6e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO00809.1 - 1.4e-09 38.1 0.1 3.3e-09 36.9 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EOO00809.1 - 0.00028 20.4 0.0 0.00036 20.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.25 EOO00809.1 - 0.0083 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1776 PF08643.10 EOO00809.1 - 0.0086 15.5 0.0 0.015 14.7 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 EOO00809.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RepC PF06504.11 EOO00809.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Replication protein C (RepC) WD40 PF00400.32 EOO00810.1 - 3.9e-13 49.7 6.8 9e-05 23.2 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Amidase PF01425.21 EOO00811.1 - 0.0007 18.7 0.0 0.0012 17.9 0.0 1.5 1 1 0 1 1 1 1 Amidase Globin PF00042.22 EOO00812.1 - 7.5e-08 32.9 0.0 1.2e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.21 EOO00812.1 - 2.1e-07 31.5 0.0 3.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EOO00812.1 - 5.4e-05 23.5 0.0 9.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EOO00812.1 - 0.0065 16.6 0.2 0.11 12.6 0.0 2.4 3 0 0 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EOO00812.1 - 0.054 13.6 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain Cation_efflux PF01545.21 EOO00813.1 - 5.6e-49 166.6 12.8 2e-48 164.8 12.8 1.7 1 1 0 1 1 1 1 Cation efflux family BCLP PF12304.8 EOO00813.1 - 0.14 11.7 1.3 0.27 10.8 1.3 1.3 1 0 0 1 1 1 0 Beta-casein like protein Prefoldin_3 PF13758.6 EOO00814.1 - 5.4e-32 109.8 0.2 1.6e-31 108.3 0.2 1.8 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 EOO00814.1 - 1.4e-27 96.3 19.5 1.3e-25 90.1 0.1 5.4 5 1 0 5 5 5 2 Domain of unknown function (DUF3835) TRAF_BIRC3_bd PF16673.5 EOO00814.1 - 0.27 11.0 1.6 0.53 10.1 0.2 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Zip PF02535.22 EOO00814.1 - 1.2 8.3 2.9 2 7.5 2.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DIOX_N PF14226.6 EOO00815.1 - 0.1 13.4 0.5 9.2 7.1 0.0 2.5 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal phage_tail_N PF08400.10 EOO00815.1 - 0.19 11.7 0.2 1.3 9.0 0.0 2.3 2 1 0 3 3 3 0 Prophage tail fibre N-terminal Scm3 PF10384.9 EOO00816.1 - 4e-24 84.1 0.4 4e-24 84.1 0.4 1.8 2 0 0 2 2 2 1 Centromere protein Scm3 Ank_5 PF13857.6 EOO00817.1 - 1.1e-10 41.5 0.1 1.7e-10 40.9 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EOO00817.1 - 2.8e-07 30.9 0.1 0.0014 19.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EOO00817.1 - 5.1e-07 29.9 0.6 0.00027 21.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EOO00817.1 - 1.1e-06 29.1 0.2 2.2e-06 28.2 0.2 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EOO00817.1 - 1.9e-05 24.7 0.0 0.002 18.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat NQR2_RnfD_RnfE PF03116.15 EOO00818.1 - 0.04 13.3 0.9 0.054 12.9 0.9 1.1 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family DUF948 PF06103.11 EOO00819.1 - 0.48 10.7 3.3 0.33 11.2 0.6 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MFS_1 PF07690.16 EOO00820.1 - 3.8e-37 128.0 50.2 9.8e-34 116.8 23.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO00820.1 - 1.7e-07 30.5 5.2 1.7e-07 30.5 5.2 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter ADH_N_2 PF16884.5 EOO00821.1 - 1.5e-30 105.3 0.0 4.2e-30 103.8 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EOO00821.1 - 0.00026 22.0 0.0 0.00087 20.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_28 PF02636.17 EOO00822.1 - 8e-38 130.6 0.0 1.4e-37 129.8 0.0 1.3 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 EOO00822.1 - 0.0014 18.5 0.0 0.0098 15.8 0.0 2.2 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Glyco_hydro_61 PF03443.14 EOO00823.1 - 1.5e-60 204.7 0.5 1.8e-60 204.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Acetyltransf_3 PF13302.7 EOO00824.1 - 6.2e-34 117.6 0.0 9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EOO00824.1 - 0.0021 18.2 0.1 0.044 14.0 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family VWA PF00092.28 EOO00825.1 - 5.1e-13 49.6 0.4 9.1e-13 48.8 0.4 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EOO00825.1 - 1.8e-10 41.4 0.1 3.5e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EOO00825.1 - 0.0062 15.9 0.3 0.15 11.4 0.0 2.1 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein VSP PF03302.13 EOO00825.1 - 0.1 11.4 1.7 0.17 10.7 1.7 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein BACON PF13004.7 EOO00825.1 - 5.6 7.0 9.9 1.8 8.6 0.2 4.0 4 0 0 4 4 4 0 Putative binding domain, N-terminal ABC2_membrane PF01061.24 EOO00826.1 - 1.1e-92 309.2 49.5 2.3e-49 167.7 20.4 2.4 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.12 EOO00826.1 - 8.8e-37 124.9 6.8 2.2e-32 110.8 0.1 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 EOO00826.1 - 1.1e-34 119.9 0.0 2.9e-16 60.2 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 EOO00826.1 - 1.4e-15 57.7 0.0 3.9e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EOO00826.1 - 8.8e-07 29.5 0.7 0.00033 21.1 0.1 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.6 EOO00826.1 - 9.6e-07 28.6 0.0 4.5e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EOO00826.1 - 2.9e-05 24.1 0.0 0.01 15.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 EOO00826.1 - 0.0001 22.8 0.0 0.07 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EOO00826.1 - 0.00038 20.4 0.3 0.92 9.3 0.1 2.7 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EOO00826.1 - 0.00046 20.4 0.0 0.14 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EOO00826.1 - 0.001 18.8 0.6 0.037 13.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.6 EOO00826.1 - 0.0034 17.8 0.1 2 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EOO00826.1 - 0.0034 16.9 0.0 2.8 7.3 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain HalX PF08663.10 EOO00826.1 - 0.0058 16.9 0.4 0.51 10.7 0.0 2.4 2 0 0 2 2 2 1 HalX domain AAA_22 PF13401.6 EOO00826.1 - 0.0069 16.7 0.2 0.9 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EOO00826.1 - 0.0089 15.8 0.5 0.33 10.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EOO00826.1 - 0.013 15.2 0.7 0.14 11.7 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PDR_assoc PF08370.11 EOO00826.1 - 0.029 14.1 0.1 0.029 14.1 0.1 3.7 4 0 0 4 4 3 0 Plant PDR ABC transporter associated AAA_28 PF13521.6 EOO00826.1 - 0.078 13.2 0.1 3.1 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EOO00826.1 - 0.082 12.8 0.1 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 EOO00826.1 - 0.1 13.1 0.2 0.23 11.9 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EOO00826.1 - 0.11 12.1 0.4 15 5.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EOO00826.1 - 0.22 11.4 0.0 5 7.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain adh_short PF00106.25 EOO00827.1 - 1.2e-28 99.9 0.0 8.4e-28 97.2 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO00827.1 - 6.4e-19 68.4 0.0 2e-18 66.8 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO00827.1 - 2.7e-06 27.4 0.1 6.4e-06 26.2 0.0 1.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 EOO00827.1 - 0.0032 16.9 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MBOAT PF03062.19 EOO00828.1 - 2.5e-49 168.5 13.8 2.5e-49 168.5 13.8 1.8 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family T4SS_CagC PF16943.5 EOO00828.1 - 0.005 17.0 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 Cag pathogenicity island, type IV secretory system Cytochrom_B561 PF03188.16 EOO00828.1 - 0.65 10.1 5.8 0.14 12.3 1.9 1.8 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 NAD_binding_8 PF13450.6 EOO00829.1 - 3.1e-07 30.5 0.0 7.2e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EOO00829.1 - 0.0017 17.5 0.0 0.0033 16.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EOO00829.1 - 0.0018 17.6 0.0 0.17 11.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EOO00829.1 - 0.0041 16.4 0.1 0.012 14.8 0.1 1.6 2 0 0 2 2 2 1 Thi4 family WYL_3 PF18488.1 EOO00829.1 - 0.026 14.9 0.0 5.5 7.4 0.0 2.6 2 0 0 2 2 2 0 WYL domain Pyr_redox_3 PF13738.6 EOO00829.1 - 0.031 13.5 0.0 0.54 9.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EOO00829.1 - 0.051 12.0 1.0 0.14 10.6 0.1 2.0 2 1 0 2 2 2 0 Flavin-binding monooxygenase-like HI0933_like PF03486.14 EOO00829.1 - 0.066 11.9 0.2 0.11 11.2 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 EOO00829.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EOO00829.1 - 0.2 10.7 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein CTP_transf_like PF01467.26 EOO00830.1 - 5.3e-07 29.9 0.0 1.4e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase-like Feld-I_B PF09252.10 EOO00830.1 - 0.041 13.8 0.7 0.33 10.9 0.0 2.3 2 0 0 2 2 2 0 Allergen Fel d I-B chain Methyltransf_23 PF13489.6 EOO00831.1 - 2.1e-15 57.0 0.0 4.2e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NmrA PF05368.13 EOO00831.1 - 2.9e-14 53.2 0.0 4.1e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Methyltransf_25 PF13649.6 EOO00831.1 - 1.2e-10 41.9 0.0 6e-09 36.5 0.0 3.2 4 0 0 4 4 3 1 Methyltransferase domain NAD_binding_10 PF13460.6 EOO00831.1 - 4.2e-10 39.8 0.0 1.1e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H-binding Methyltransf_11 PF08241.12 EOO00831.1 - 3.2e-09 37.3 0.0 5.9e-08 33.3 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO00831.1 - 1.3e-08 34.7 0.0 7.1e-07 29.1 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO00831.1 - 2.6e-07 31.3 0.0 8.3e-06 26.5 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EOO00831.1 - 0.00031 20.2 0.0 0.0047 16.3 0.0 2.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EOO00831.1 - 0.014 14.9 0.0 0.046 13.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.9 EOO00831.1 - 0.07 12.9 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Lysine methyltransferase Epimerase PF01370.21 EOO00831.1 - 0.079 12.4 0.1 6.1 6.2 0.0 2.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family tRNA_anti-codon PF01336.25 EOO00831.1 - 0.13 12.2 0.0 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain PrmA PF06325.13 EOO00831.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 EOO00831.1 - 0.16 11.3 0.0 0.99 8.7 0.0 2.2 3 0 0 3 3 3 0 O-methyltransferase domain Acyl-CoA_dh_1 PF00441.24 EOO00832.1 - 2.4e-24 86.2 0.1 4.4e-24 85.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EOO00832.1 - 2e-13 51.0 0.9 3.7e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EOO00832.1 - 1.4e-08 34.8 0.0 2.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EOO00832.1 - 6.9e-08 32.8 0.0 1.2e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PCI PF01399.27 EOO00833.1 - 4.6e-10 40.0 0.0 1.4e-09 38.4 0.0 1.9 1 1 0 1 1 1 1 PCI domain adh_short_C2 PF13561.6 EOO00834.1 - 4.1e-37 128.0 0.1 5.6e-30 104.6 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO00834.1 - 2.7e-31 108.6 0.0 4.3e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO00834.1 - 0.00014 21.8 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 KR domain PTR2 PF00854.21 EOO00835.1 - 4.9e-77 259.4 6.2 6.9e-77 258.9 6.2 1.1 1 0 0 1 1 1 1 POT family Thiolase_N PF00108.23 EOO00836.1 - 8.4e-85 284.3 2.6 1.3e-84 283.7 2.6 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EOO00836.1 - 5.7e-45 151.9 0.1 1.5e-44 150.5 0.1 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EOO00836.1 - 0.0002 21.0 1.0 0.00046 19.8 0.4 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EOO00836.1 - 0.16 11.8 5.6 0.78 9.6 0.1 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Totivirus_coat PF05518.11 EOO00837.1 - 0.0075 14.4 0.3 0.0099 14.0 0.3 1.1 1 0 0 1 1 1 1 Totivirus coat protein MFS_1 PF07690.16 EOO00837.1 - 0.013 14.4 33.6 0.85 8.5 33.1 2.2 1 1 0 1 1 1 0 Major Facilitator Superfamily GNAT_acetyltr_2 PF13718.6 EOO00838.1 - 3e-95 318.0 0.0 5.4e-95 317.1 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EOO00838.1 - 5.2e-93 311.1 0.0 8.7e-93 310.4 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EOO00838.1 - 6.7e-65 218.2 0.0 3.1e-64 216.1 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 EOO00838.1 - 3.8e-33 113.3 0.0 9.4e-33 112.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 EOO00838.1 - 0.00026 20.8 0.1 0.015 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EOO00838.1 - 0.0022 18.3 0.0 0.086 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Acetyltransf_1 PF00583.25 EOO00838.1 - 0.056 13.7 0.0 1.2 9.4 0.0 2.8 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family GHMP_kinases_N PF00288.26 EOO00838.1 - 0.085 13.1 0.2 0.22 11.8 0.2 1.6 1 0 0 1 1 1 0 GHMP kinases N terminal domain Sulfatase PF00884.23 EOO00839.1 - 3.1e-63 214.0 0.4 3.8e-63 213.7 0.4 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 EOO00839.1 - 0.0077 16.5 0.1 0.018 15.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) E1-E2_ATPase PF00122.20 EOO00841.1 - 2.2e-50 170.7 0.4 7.5e-50 169.0 0.4 2.0 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 EOO00841.1 - 3.5e-46 155.5 1.4 2.6e-12 47.0 0.1 4.7 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 EOO00841.1 - 3.2e-39 135.4 3.2 8.3e-39 134.1 3.2 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EOO00841.1 - 4e-07 30.0 1.3 5.3e-05 23.1 0.4 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EOO00841.1 - 0.00018 22.0 0.0 0.00045 20.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EOO00841.1 - 0.031 14.3 0.3 0.11 12.6 0.1 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF1656 PF07869.12 EOO00841.1 - 0.23 11.5 3.4 0.54 10.3 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) RelB_N PF18506.1 EOO00841.1 - 4.5 7.2 6.5 39 4.1 0.2 3.4 3 0 0 3 3 3 0 RelB Antitoxin alpha helical domain DUF1996 PF09362.10 EOO00842.1 - 2.4e-46 158.6 0.1 4.5e-46 157.8 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1996) ThrE PF06738.12 EOO00843.1 - 1.8e-73 246.9 7.7 2.1e-69 233.5 2.4 2.4 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EOO00843.1 - 1.8e-08 34.6 27.6 5.2e-07 29.8 0.5 3.5 4 0 0 4 4 4 3 Threonine/Serine exporter, ThrE MFS_1 PF07690.16 EOO00844.1 - 3.8e-12 45.8 6.1 7e-10 38.3 2.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO00844.1 - 5.8e-07 28.7 0.5 9.8e-07 28.0 0.5 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter FtsX PF02687.21 EOO00844.1 - 3.9 8.0 11.7 31 5.1 7.9 3.1 2 1 0 2 2 2 0 FtsX-like permease family adh_short PF00106.25 EOO00845.1 - 6e-06 25.9 0.0 8.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO00845.1 - 0.00033 20.3 0.0 0.00056 19.5 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Histidinol_dh PF00815.20 EOO00846.1 - 9.8e-119 397.0 0.5 1.3e-118 396.6 0.5 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase ThiF PF00899.21 EOO00846.1 - 0.027 13.8 0.0 3.1 7.1 0.1 2.2 2 0 0 2 2 2 0 ThiF family PAS_10 PF13596.6 EOO00846.1 - 0.11 13.1 0.3 0.54 10.9 0.1 2.0 1 1 1 2 2 2 0 PAS domain Sugar_tr PF00083.24 EOO00848.1 - 1.1e-31 110.2 7.9 3.4e-20 72.3 0.2 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter BslA PF17735.1 EOO00848.1 - 0.21 11.6 0.3 1.2 9.1 0.1 2.1 2 1 0 2 2 2 0 Biofilm surface layer A UDG PF03167.19 EOO00849.1 - 1.1e-23 83.9 0.1 2.3e-23 82.9 0.1 1.5 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily DUF1772 PF08592.11 EOO00850.1 - 1.3e-24 87.0 1.6 1.5e-24 86.9 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) ABC_membrane PF00664.23 EOO00851.1 - 5.9e-22 78.6 5.0 1.1e-21 77.8 5.0 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EOO00851.1 - 5.9e-09 36.6 0.0 2.1e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EOO00851.1 - 0.0006 19.3 0.0 0.00095 18.7 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EOO00851.1 - 0.0011 18.8 0.9 0.0022 17.9 0.2 1.8 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Peptidase_M16 PF00675.20 EOO00852.1 - 9.7e-57 191.1 0.5 2.7e-56 189.7 0.5 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EOO00852.1 - 4.7e-39 134.3 0.0 8.3e-37 127.0 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain M16C_assoc PF08367.11 EOO00852.1 - 0.016 14.4 0.2 0.028 13.6 0.2 1.4 1 0 0 1 1 1 0 Peptidase M16C associated RbsD_FucU PF05025.13 EOO00852.1 - 0.064 13.7 0.2 0.28 11.6 0.1 2.1 2 0 0 2 2 2 0 RbsD / FucU transport protein family Pro_CA PF00484.19 EOO00853.1 - 0.00021 21.6 1.5 0.0023 18.2 1.5 2.2 1 1 0 1 1 1 1 Carbonic anhydrase Ribosomal_S17_N PF16205.5 EOO00854.1 - 2.9e-33 114.1 0.3 4.7e-33 113.4 0.3 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EOO00854.1 - 9e-27 93.0 0.4 1.8e-26 92.0 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 WD40 PF00400.32 EOO00855.1 - 5.5e-19 68.2 4.0 0.00026 21.7 0.1 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO00855.1 - 2.9e-15 56.3 0.2 3.3e-06 27.3 0.0 4.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EOO00855.1 - 9.9e-06 25.6 0.0 0.011 15.6 0.0 2.7 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 EOO00855.1 - 0.005 15.9 0.0 0.08 12.0 0.0 2.2 1 1 1 2 2 2 1 Coatomer WD associated region Pyocin_S PF06958.12 EOO00855.1 - 0.04 14.5 0.8 7.6 7.1 0.3 2.3 2 0 0 2 2 2 0 S-type Pyocin DPPIV_N PF00930.21 EOO00855.1 - 0.049 12.4 0.1 11 4.6 0.0 2.7 1 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40_like PF17005.5 EOO00855.1 - 0.088 12.1 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 WD40-like domain IKI3 PF04762.12 EOO00855.1 - 0.13 10.3 0.2 2.2 6.1 0.0 1.9 1 1 0 2 2 2 0 IKI3 family MMS1_N PF10433.9 EOO00855.1 - 0.13 10.9 0.0 0.47 9.0 0.0 1.8 1 1 1 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term PD40 PF07676.12 EOO00855.1 - 0.18 11.8 0.6 0.8 9.7 0.3 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat 4HBT_2 PF13279.6 EOO00856.1 - 1.5e-07 31.9 0.0 2.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF2967 PF11179.8 EOO00856.1 - 0.045 11.9 0.1 0.16 10.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) TMEM191C PF15194.6 EOO00856.1 - 0.059 13.5 0.6 7.2 6.8 0.0 2.6 2 0 0 2 2 2 0 TMEM191C family APG6 PF04111.12 EOO00857.1 - 8.4e-70 234.4 0.0 1.2e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EOO00857.1 - 2.2e-39 135.0 14.9 3.9e-39 134.2 14.9 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region UPF0242 PF06785.11 EOO00857.1 - 0.82 9.8 10.8 1.6 8.8 10.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ribophorin_II PF05817.14 EOO00858.1 - 1.3e-33 116.5 0.0 1.7e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Wzy_C PF04932.15 EOO00858.1 - 0.5 10.0 3.2 0.47 10.1 1.6 1.7 1 1 1 2 2 2 0 O-Antigen ligase Aldedh PF00171.22 EOO00859.1 - 2.7e-158 527.3 0.0 3.1e-158 527.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EOO00859.1 - 0.056 12.9 0.0 3.8 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) ELO PF01151.18 EOO00860.1 - 1.5e-59 201.6 13.5 1.8e-59 201.3 13.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Glyco_hydro_57 PF03065.15 EOO00860.1 - 0.066 12.4 0.1 0.091 11.9 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 adh_short_C2 PF13561.6 EOO00861.1 - 1.6e-57 194.8 0.1 1.9e-57 194.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO00861.1 - 8.4e-46 155.9 0.3 9.9e-46 155.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO00861.1 - 2.6e-14 53.6 0.2 3.6e-14 53.1 0.2 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EOO00861.1 - 0.047 13.1 0.1 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase TPR_12 PF13424.6 EOO00862.1 - 0.0012 19.1 1.5 0.0099 16.2 0.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat DUF4919 PF16266.5 EOO00862.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4919) TPR_4 PF07721.14 EOO00862.1 - 0.19 12.5 3.4 2.7 8.9 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.18 EOO00863.1 - 8.8e-10 38.0 0.0 1.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF294 PF03445.13 EOO00863.1 - 0.019 14.8 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 DUF4131 PF13567.6 EOO00864.1 - 9.9 5.8 7.9 4.9 6.8 0.3 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) Ribosomal_L18A PF01775.17 EOO00865.1 - 1.3e-55 186.7 0.2 1.6e-55 186.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A FMO-like PF00743.19 EOO00866.1 - 1.2e-14 53.7 0.2 4.7e-11 41.8 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EOO00866.1 - 9.4e-11 41.8 0.0 2.4e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EOO00866.1 - 6.5e-05 23.0 0.0 0.00021 21.3 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EOO00866.1 - 0.00013 21.3 0.0 0.7 9.0 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EOO00866.1 - 0.0048 16.5 0.0 0.036 13.7 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EOO00866.1 - 0.0074 15.6 0.8 0.19 11.0 0.0 3.1 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EOO00866.1 - 0.2 11.7 0.0 1.4 9.0 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Glyco_transf_28 PF03033.20 EOO00867.1 - 9.2e-19 67.9 1.3 2.6e-10 40.5 0.1 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EOO00867.1 - 1.3e-05 24.2 0.1 2.9e-05 23.1 0.1 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EOO00867.1 - 3e-05 24.1 0.0 5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Hydantoinase_B PF02538.14 EOO00868.1 - 3.2e-206 685.7 0.6 5e-206 685.1 0.6 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EOO00868.1 - 8.3e-100 333.8 0.0 1.9e-99 332.6 0.0 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase F_bP_aldolase PF01116.20 EOO00868.1 - 2.5e-77 260.1 0.1 5e-77 259.1 0.1 1.5 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II adh_short PF00106.25 EOO00869.1 - 5.2e-34 117.4 0.4 7.4e-34 116.9 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO00869.1 - 4e-24 85.5 1.5 5.7e-24 85.0 1.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO00869.1 - 5e-09 36.3 0.3 7.7e-09 35.7 0.3 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EOO00869.1 - 5.5e-07 29.7 2.0 6e-07 29.5 1.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EOO00869.1 - 7.4e-05 22.3 0.1 0.00011 21.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EOO00869.1 - 0.0095 15.1 0.8 0.015 14.4 0.8 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 EOO00869.1 - 0.011 15.3 0.3 0.02 14.5 0.2 1.4 1 1 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 EOO00870.1 - 1.1e-14 54.5 0.0 3.1e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EOO00870.1 - 2.4e-08 34.1 0.1 4.3e-08 33.3 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EOO00870.1 - 3.7e-08 33.8 0.0 9e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EOO00870.1 - 3.5e-06 26.2 0.0 0.026 13.5 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EOO00870.1 - 0.00012 21.8 0.0 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EOO00870.1 - 0.0013 18.0 0.0 0.19 10.9 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein Sacchrp_dh_NADP PF03435.18 EOO00870.1 - 0.0026 18.0 0.0 0.0041 17.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Bromodomain PF00439.25 EOO00871.1 - 4.3e-24 84.4 0.6 8.2e-24 83.5 0.6 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EOO00871.1 - 6.5e-08 32.8 0.0 1.2e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EOO00871.1 - 6.6e-07 29.3 0.2 1.7e-06 28.0 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EOO00871.1 - 0.00027 21.3 0.1 0.00061 20.2 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fucose_iso_N2 PF07882.12 EOO00871.1 - 0.17 11.4 0.2 0.29 10.7 0.2 1.2 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain FR47 PF08445.10 EOO00871.1 - 0.2 11.6 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein RasGAP PF00616.19 EOO00872.1 - 1.7e-55 187.9 0.0 4.5e-55 186.6 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EOO00872.1 - 6.5e-48 162.4 4.3 6.5e-48 162.4 4.3 2.4 2 1 0 2 2 2 1 RasGAP C-terminus IQ PF00612.27 EOO00872.1 - 1.4e-08 33.8 14.8 1.3 9.0 0.1 7.4 7 0 0 7 7 7 4 IQ calmodulin-binding motif DUF4226 PF10774.9 EOO00872.1 - 0.12 12.7 2.9 2.1 8.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) Sipho_Gp157 PF05565.11 EOO00872.1 - 2.8 7.9 15.0 0.3 11.1 1.0 3.3 3 0 0 3 3 3 0 Siphovirus Gp157 Methyltransf_23 PF13489.6 EOO00873.1 - 1.5e-12 47.7 0.0 7.4e-12 45.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO00873.1 - 1.3e-05 25.0 0.0 0.0056 16.5 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EOO00873.1 - 8.8e-05 23.1 0.1 0.31 11.8 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain MTS PF05175.14 EOO00873.1 - 0.014 14.9 0.0 0.08 12.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.12 EOO00873.1 - 0.038 14.7 0.0 2 9.2 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 EOO00873.1 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 EOO00873.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Herpes_UL69 PF05459.12 EOO00873.1 - 0.21 10.9 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus transcriptional regulator family DUF155 PF02582.14 EOO00874.1 - 1.6e-55 187.9 0.1 3e-55 187.0 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 ECSCR PF15820.5 EOO00874.1 - 0.022 14.6 0.2 0.052 13.4 0.2 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Atg14 PF10186.9 EOO00876.1 - 5.4e-42 144.0 12.8 4.5e-34 118.0 10.0 2.1 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 JIP_LZII PF16471.5 EOO00876.1 - 0.17 12.1 3.3 0.55 10.5 1.5 2.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II FAM76 PF16046.5 EOO00876.1 - 0.22 10.8 7.9 0.32 10.3 7.9 1.1 1 0 0 1 1 1 0 FAM76 protein DUF501 PF04417.12 EOO00876.1 - 0.73 9.6 2.8 1.1 9.1 1.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF501) TMPIT PF07851.13 EOO00876.1 - 1.5 8.0 4.6 2.1 7.5 4.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein FMO-like PF00743.19 EOO00877.1 - 6.1e-12 44.7 0.0 7.2e-09 34.6 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EOO00877.1 - 0.00076 18.8 0.0 0.0026 17.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EOO00877.1 - 0.007 16.6 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EOO00877.1 - 0.01 15.1 0.0 0.9 8.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LBR_tudor PF09465.10 EOO00877.1 - 0.12 12.2 0.1 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain 2OG-FeII_Oxy PF03171.20 EOO00878.1 - 0.023 15.2 0.0 0.052 14.0 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily SprT-like PF10263.9 EOO00879.1 - 5.9e-17 61.6 0.0 9.6e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 SprT-like family Pkinase PF00069.25 EOO00880.1 - 3.7e-45 154.3 0.0 6.9e-44 150.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO00880.1 - 1.1e-31 110.1 0.0 1.5e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EOO00880.1 - 0.002 17.5 0.0 0.014 14.8 0.0 2.3 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EOO00880.1 - 0.0083 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like ArabFuran-catal PF09206.11 EOO00881.1 - 8e-150 498.5 13.2 1.2e-149 497.9 13.2 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 EOO00881.1 - 2.9e-56 189.3 3.2 4.4e-56 188.7 3.2 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain DivIC PF04977.15 EOO00882.1 - 0.031 14.0 2.9 1.6 8.6 0.0 3.2 3 0 0 3 3 3 0 Septum formation initiator HCMV_UL139 PF12507.8 EOO00882.1 - 0.12 12.7 1.3 0.48 10.8 0.8 2.3 2 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein GAS PF13851.6 EOO00882.1 - 0.13 11.6 2.5 1 8.7 0.6 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 EOO00882.1 - 0.41 11.2 11.5 6.7 7.3 7.6 3.5 2 1 1 3 3 3 0 Apg6 coiled-coil region Spc7 PF08317.11 EOO00882.1 - 2.9 6.7 6.0 1.1 8.1 2.9 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein CCDC-167 PF15188.6 EOO00882.1 - 9.8 6.6 8.9 8.5 6.8 0.1 3.5 2 1 2 4 4 4 0 Coiled-coil domain-containing protein 167 AAA PF00004.29 EOO00883.1 - 1.6e-17 64.2 0.0 3.8e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EOO00883.1 - 7.5e-05 23.2 0.1 0.00051 20.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Coilin_N PF15862.5 EOO00883.1 - 0.0011 18.7 2.4 0.0011 18.7 2.4 4.6 4 1 0 4 4 4 1 Coilin N-terminus AAA_33 PF13671.6 EOO00883.1 - 0.025 14.7 0.1 3.6 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zot PF05707.12 EOO00883.1 - 0.036 13.7 0.2 0.48 10.0 0.1 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) CPT PF07931.12 EOO00883.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.6 EOO00883.1 - 0.067 13.5 1.8 0.55 10.5 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 EOO00883.1 - 0.081 12.9 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF1514 PF07438.11 EOO00883.1 - 0.95 9.4 3.3 13 5.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1514) ABC_tran PF00005.27 EOO00885.1 - 1.9e-51 174.2 0.0 1.7e-30 106.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EOO00885.1 - 1.4e-40 139.7 25.7 3.4e-28 99.1 8.5 3.6 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 EOO00885.1 - 3.3e-10 39.8 0.0 0.00011 21.7 0.0 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EOO00885.1 - 5.8e-05 23.5 1.9 0.055 13.8 0.1 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EOO00885.1 - 9.5e-05 22.7 0.0 0.48 10.7 0.0 3.4 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 EOO00885.1 - 0.00061 18.9 0.0 0.14 11.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EOO00885.1 - 0.0022 17.9 0.1 2.2 8.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EOO00885.1 - 0.0037 17.0 0.5 3.2 7.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EOO00885.1 - 0.004 17.2 2.2 0.064 13.3 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 EOO00885.1 - 0.0045 16.6 0.0 0.67 9.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EOO00885.1 - 0.021 14.9 2.8 1.3 9.0 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain DUF2075 PF09848.9 EOO00885.1 - 0.027 13.7 0.1 0.48 9.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EOO00885.1 - 0.037 13.7 0.2 2.8 7.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 EOO00885.1 - 0.044 13.3 0.3 5.8 6.4 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 EOO00885.1 - 0.073 13.3 0.1 15 5.9 0.0 3.3 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EOO00885.1 - 0.078 12.8 0.4 19 4.9 0.0 3.8 5 0 0 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EOO00885.1 - 0.12 12.8 0.7 14 6.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EOO00885.1 - 0.15 11.8 0.0 4.9 6.9 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AMP-binding PF00501.28 EOO00886.1 - 7.9e-74 248.7 0.0 1e-73 248.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ECH_1 PF00378.20 EOO00886.1 - 7.8e-44 149.9 0.1 1.1e-43 149.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EOO00886.1 - 2.3e-31 109.5 0.5 1.8e-30 106.6 0.5 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AMP-binding_C PF13193.6 EOO00886.1 - 4.2e-11 43.6 0.0 1.3e-10 42.1 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LETM1 PF07766.13 EOO00887.1 - 5.9e-106 353.7 0.8 5.9e-106 353.7 0.8 1.7 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 EOO00887.1 - 0.00043 20.0 0.1 0.32 10.8 0.0 3.4 3 0 0 3 3 3 1 SAP domain BPL_N PF09825.9 EOO00887.1 - 5 6.1 9.7 0.11 11.5 0.4 2.3 2 1 0 2 2 2 0 Biotin-protein ligase, N terminal adh_short_C2 PF13561.6 EOO00888.1 - 1.6e-44 152.2 0.1 2e-44 151.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO00888.1 - 2.4e-36 125.1 0.1 3.4e-36 124.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO00888.1 - 1e-07 32.1 0.2 1.4e-07 31.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EOO00888.1 - 0.15 11.9 2.3 3 7.7 0.3 2.8 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RRM_1 PF00076.22 EOO00889.1 - 7.5e-14 51.3 0.0 1.1e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_6 PF12697.7 EOO00890.1 - 1.2e-13 52.3 0.6 1.9e-13 51.5 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EOO00890.1 - 4.5e-12 46.2 0.0 6.1e-10 39.2 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EOO00890.1 - 5.8e-08 32.3 0.1 4.8e-07 29.3 0.1 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 EOO00890.1 - 0.0009 18.9 0.7 0.0014 18.2 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase LIDHydrolase PF10230.9 EOO00890.1 - 0.0014 18.3 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Peptidase_S15 PF02129.18 EOO00890.1 - 0.005 16.5 0.2 0.071 12.7 0.2 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EOO00890.1 - 0.0098 15.4 0.0 0.31 10.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family LIP PF03583.14 EOO00890.1 - 0.029 13.7 3.0 0.055 12.8 2.7 1.6 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_3 PF07859.13 EOO00890.1 - 0.03 14.2 0.1 0.052 13.4 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EOO00890.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 EOO00890.1 - 0.11 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Heme_oxygenase PF01126.20 EOO00890.1 - 0.15 11.9 0.1 0.24 11.2 0.1 1.2 1 0 0 1 1 1 0 Heme oxygenase DUF3530 PF12048.8 EOO00890.1 - 0.22 10.9 0.2 0.32 10.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) ChAPs PF09295.10 EOO00893.1 - 6.7e-153 509.4 0.0 8.5e-153 509.0 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 EOO00893.1 - 2.3e-05 24.8 1.5 0.32 11.9 0.1 4.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EOO00893.1 - 0.00023 21.2 0.1 0.097 12.8 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EOO00893.1 - 0.00024 21.0 0.8 0.12 12.6 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EOO00893.1 - 0.00041 20.3 0.2 0.051 13.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EOO00893.1 - 0.00062 19.6 2.8 0.69 10.1 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EOO00893.1 - 0.0076 16.8 0.5 14 6.6 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EOO00893.1 - 0.019 15.5 0.1 1.9 9.1 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EOO00893.1 - 0.027 14.3 0.2 8.2 6.4 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EOO00893.1 - 0.041 14.2 0.7 5.9 7.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat 60KD_IMP PF02096.20 EOO00894.1 - 1.5e-13 50.9 8.4 1.5e-13 50.9 8.4 1.5 2 0 0 2 2 2 1 60Kd inner membrane protein BLM10_N PF16547.5 EOO00894.1 - 0.11 12.8 1.9 5.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, N-terminal Glyco_transf_21 PF13506.6 EOO00895.1 - 1.1e-14 54.3 0.1 8.6e-05 22.1 0.0 3.4 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EOO00895.1 - 1.6e-08 34.8 0.0 3.1e-07 30.5 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EOO00895.1 - 0.067 13.0 0.1 0.65 9.8 0.1 2.2 1 1 0 1 1 1 0 Glycosyl transferase family 2 Amino_oxidase PF01593.24 EOO00896.1 - 1.1e-46 160.1 0.4 4.5e-28 98.7 0.3 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.21 EOO00896.1 - 7e-17 61.6 0.0 1.5e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.6 EOO00896.1 - 8e-12 45.2 0.2 2.1e-11 43.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EOO00896.1 - 1e-08 34.7 0.4 1.6e-08 34.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EOO00896.1 - 1.1e-07 31.4 0.1 1.9e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EOO00896.1 - 9.7e-07 28.7 2.2 3.7e-06 26.8 2.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EOO00896.1 - 2.7e-06 27.0 0.8 4e-06 26.5 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EOO00896.1 - 4.9e-05 22.2 0.8 0.00014 20.7 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 EOO00896.1 - 5.9e-05 22.4 0.5 9.6e-05 21.7 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EOO00896.1 - 6.8e-05 22.3 0.1 0.0073 15.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EOO00896.1 - 0.00011 21.4 0.3 0.00069 18.8 0.6 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 EOO00896.1 - 0.00012 22.6 0.1 0.00036 21.0 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EOO00896.1 - 0.00015 21.2 0.2 0.00023 20.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EOO00896.1 - 0.00043 19.5 1.6 0.00066 18.9 0.4 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EOO00896.1 - 0.012 15.0 0.2 0.026 13.8 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CwfJ_C_2 PF04676.14 EOO00897.1 - 8e-29 100.4 0.1 2.4e-28 98.9 0.1 1.9 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 EOO00897.1 - 4.6e-23 81.4 0.0 8.1e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 FumaraseC_C PF10415.9 EOO00897.1 - 0.12 12.8 4.2 1.1 9.7 0.2 3.3 3 0 0 3 3 3 0 Fumarase C C-terminus Glyco_hydro_18 PF00704.28 EOO00898.1 - 1.2e-53 182.9 0.0 1.4e-53 182.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TOM13 PF08219.11 EOO00899.1 - 3.7e-37 126.1 0.0 4.7e-37 125.8 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 DUF3390 PF11870.8 EOO00899.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) Glyoxalase PF00903.25 EOO00900.1 - 5.8e-06 26.5 4.8 0.00015 22.0 2.3 2.8 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ADH_zinc_N PF00107.26 EOO00901.1 - 5.5e-06 26.4 0.1 1.7e-05 24.8 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EOO00901.1 - 9.1e-05 22.3 0.1 0.00035 20.4 0.1 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EOO00901.1 - 0.041 14.9 0.1 0.12 13.5 0.1 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Gasdermin_C PF17708.1 EOO00901.1 - 0.21 11.7 0.0 0.31 11.1 0.0 1.2 1 0 0 1 1 1 0 Gasdermin PUB domain adh_short PF00106.25 EOO00902.1 - 3.6e-19 69.0 1.0 7.8e-19 67.9 0.1 1.7 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO00902.1 - 2.2e-09 37.3 1.7 1.6e-08 34.4 1.1 2.2 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO00902.1 - 0.00016 21.7 0.0 0.00022 21.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EOO00902.1 - 0.007 15.5 0.0 0.0096 15.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein zf-C2H2 PF00096.26 EOO00903.1 - 2.1e-06 27.9 7.7 0.019 15.4 1.1 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 EOO00903.1 - 2.2e-05 24.1 8.8 0.018 14.8 1.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 EOO00903.1 - 3.2e-05 24.4 10.2 0.00082 20.0 1.5 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EOO00903.1 - 0.037 14.5 0.8 0.037 14.5 0.8 3.6 3 1 0 3 3 3 0 Zinc-finger double domain zf-Di19 PF05605.12 EOO00903.1 - 0.15 12.4 3.5 0.35 11.2 3.5 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding RSN1_7TM PF02714.15 EOO00905.1 - 3e-76 256.3 23.8 4.3e-76 255.8 23.8 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EOO00905.1 - 5.6e-39 134.2 0.0 7.7e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EOO00905.1 - 2.2e-37 128.2 1.0 5.9e-37 126.8 1.0 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport Aldo_ket_red PF00248.21 EOO00906.1 - 7.2e-49 166.6 0.0 4.9e-47 160.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Transferase PF02458.15 EOO00907.1 - 1e-22 80.5 0.0 3.2e-20 72.2 0.0 2.2 1 1 0 1 1 1 1 Transferase family Ion_trans PF00520.31 EOO00908.1 - 0.41 9.8 3.4 0.57 9.4 3.4 1.1 1 0 0 1 1 1 0 Ion transport protein Gpr1_Fun34_YaaH PF01184.19 EOO00909.1 - 5.8e-16 58.7 20.9 5.7e-13 49.0 16.0 2.8 1 1 2 3 3 3 3 GPR1/FUN34/yaaH family Polyketide_cyc2 PF10604.9 EOO00910.1 - 1.8e-05 25.1 0.4 2.1e-05 24.8 0.4 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EOO00910.1 - 0.025 14.8 0.2 0.039 14.1 0.2 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DUF4520 PF15016.6 EOO00910.1 - 0.027 14.5 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) LBR_tudor PF09465.10 EOO00910.1 - 0.054 13.3 0.2 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain SnoaL_4 PF13577.6 EOO00911.1 - 3e-09 37.1 0.3 4.2e-09 36.6 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain Pkinase PF00069.25 EOO00912.1 - 4.3e-40 137.7 0.0 5.3e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO00912.1 - 2.5e-21 76.1 0.0 3e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EOO00912.1 - 0.00025 21.1 0.0 0.0003 20.8 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EOO00912.1 - 0.0024 17.6 0.0 0.21 11.2 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EOO00912.1 - 0.0025 17.2 0.0 0.0034 16.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EOO00912.1 - 0.0045 15.8 0.0 0.0061 15.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase UL11 PF11094.8 EOO00912.1 - 0.018 14.9 0.3 0.043 13.7 0.1 1.7 1 1 1 2 2 2 0 Membrane-associated tegument protein Haspin_kinase PF12330.8 EOO00912.1 - 0.035 13.0 0.0 0.046 12.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EOO00912.1 - 0.065 12.2 0.1 0.14 11.1 0.1 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 EOO00912.1 - 0.1 12.2 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 EOO00912.1 - 0.2 11.0 0.0 0.72 9.1 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Tannase PF07519.11 EOO00913.1 - 7.3e-151 503.2 4.1 8.5e-151 503.0 4.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase NDUFA12 PF05071.16 EOO00914.1 - 2.3e-30 105.3 3.3 3e-30 104.9 3.3 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Annexin PF00191.20 EOO00915.1 - 1.5e-72 239.6 1.3 7.4e-19 67.6 0.3 4.2 4 0 0 4 4 4 4 Annexin UBA_2 PF08587.11 EOO00915.1 - 0.046 13.8 0.1 0.23 11.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) Gtr1_RagA PF04670.12 EOO00916.1 - 6.5e-96 320.2 0.0 9.1e-96 319.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EOO00916.1 - 7e-09 35.9 0.0 1.3e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EOO00916.1 - 7e-08 32.2 0.1 1.5e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 Ras family Arf PF00025.21 EOO00916.1 - 2.5e-07 30.3 0.0 4.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EOO00916.1 - 3e-06 27.3 0.0 6.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EOO00916.1 - 0.0011 18.2 1.8 0.42 9.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 EOO00916.1 - 0.0012 18.8 0.6 0.1 12.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EOO00916.1 - 0.0023 17.6 0.4 0.059 13.1 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EOO00916.1 - 0.014 15.9 0.0 0.031 14.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.10 EOO00916.1 - 0.041 13.3 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF815 PF05673.13 EOO00916.1 - 0.044 13.0 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TMA7 PF09072.10 EOO00917.1 - 4.9e-25 88.1 22.7 5.4e-25 88.0 22.7 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 MFS_1 PF07690.16 EOO00918.1 - 5e-07 29.0 7.1 3.7e-05 22.8 5.8 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily YibE_F PF07907.11 EOO00918.1 - 0.023 14.2 4.0 0.27 10.7 0.1 2.2 2 0 0 2 2 2 0 YibE/F-like protein GPI2 PF06432.11 EOO00918.1 - 0.095 12.1 1.5 0.12 11.8 0.8 1.5 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase E1-E2_ATPase PF00122.20 EOO00919.1 - 1.2e-36 126.0 8.7 1.7e-30 105.9 0.1 3.4 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EOO00919.1 - 6e-31 107.6 2.9 6e-31 107.6 2.9 2.8 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EOO00919.1 - 3.9e-21 74.9 0.0 9.4e-21 73.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EOO00919.1 - 4.2e-19 69.7 0.0 1.3e-14 55.1 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EOO00919.1 - 5.7e-17 61.2 0.2 3.7e-16 58.6 0.0 2.5 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EOO00919.1 - 7.7e-08 32.4 0.3 8.4e-06 25.7 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SurE PF01975.17 EOO00920.1 - 4.5e-30 104.9 0.1 1e-29 103.8 0.0 1.5 1 1 1 2 2 2 1 Survival protein SurE Dioxygenase_C PF00775.21 EOO00921.1 - 2.4e-08 33.7 0.0 3.9e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Catalase PF00199.19 EOO00922.1 - 2.6e-178 593.0 0.0 3.2e-178 592.7 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EOO00922.1 - 8.1e-16 58.0 0.0 2e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive A_deaminase PF00962.22 EOO00923.1 - 4.6e-40 137.9 0.0 5.7e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase NOB1_Zn_bind PF08772.11 EOO00925.1 - 3.9e-32 110.2 3.4 6.7e-32 109.5 3.4 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 EOO00925.1 - 1.2e-31 109.0 2.6 1.5e-31 108.8 0.1 2.3 3 0 0 3 3 2 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 EOO00925.1 - 0.029 14.0 5.1 0.05 13.3 0.6 2.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 EOO00925.1 - 0.05 13.6 0.7 0.092 12.8 0.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon Rhodanese_C PF12368.8 EOO00925.1 - 0.051 13.9 1.2 0.095 13.1 1.2 1.3 1 0 0 1 1 1 0 Rhodanase C-terminal DUF2616 PF11077.8 EOO00925.1 - 0.082 12.6 0.2 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) DUF2321 PF10083.9 EOO00925.1 - 0.1 12.2 0.4 0.25 11.0 0.4 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) MqsA_antitoxin PF15731.5 EOO00925.1 - 0.16 12.1 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HypA PF01155.19 EOO00925.1 - 0.18 11.8 1.3 0.32 11.0 0.2 1.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Nudix_N_2 PF14803.6 EOO00925.1 - 2.2 8.2 3.9 1.7 8.6 1.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal WRNPLPNID PF15017.6 EOO00925.1 - 2.6 9.0 17.9 40 5.2 18.0 2.7 1 1 0 1 1 1 0 Putative WW-binding domain and destruction box PTS_EIIA_2 PF00359.22 EOO00927.1 - 0.065 13.1 0.1 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 GMC_oxred_C PF05199.13 EOO00928.1 - 1.4e-27 97.0 0.0 2.9e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EOO00928.1 - 2.5e-26 92.7 0.0 1.2e-25 90.5 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EOO00928.1 - 0.00086 18.6 0.0 0.0019 17.5 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EOO00928.1 - 0.0034 17.6 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EOO00928.1 - 0.0065 15.6 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EOO00928.1 - 0.068 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 EOO00928.1 - 0.078 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF1737 PF08410.10 EOO00928.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Lycopene_cycl PF05834.12 EOO00928.1 - 0.18 10.8 0.0 0.37 9.8 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EOO00928.1 - 0.28 10.4 0.4 10 5.3 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPR_19 PF14559.6 EOO00929.1 - 0.0013 19.2 3.8 7.7 7.1 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EOO00929.1 - 0.027 14.8 0.0 9.7 6.8 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EOO00929.1 - 0.068 13.8 9.1 5.7 7.7 0.4 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EOO00929.1 - 0.091 12.9 0.8 0.31 11.2 0.8 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Mei5_like PF17021.5 EOO00929.1 - 0.098 12.7 0.3 0.41 10.7 0.0 2.2 2 0 0 2 2 2 0 Putative double-strand recombination repair-like TPR_11 PF13414.6 EOO00929.1 - 3.8 7.3 4.8 45 3.8 0.1 4.1 4 0 0 4 4 4 0 TPR repeat TPR_14 PF13428.6 EOO00929.1 - 9.9 7.3 14.1 18 6.5 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat HlyIII PF03006.20 EOO00930.1 - 1.2e-35 123.2 9.3 2.5e-31 109.1 6.0 2.1 1 1 1 2 2 2 2 Haemolysin-III related DUF4530 PF15039.6 EOO00930.1 - 0.00024 21.2 0.0 0.0004 20.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4530) TssN PF17555.2 EOO00930.1 - 0.8 9.0 5.7 0.13 11.6 0.6 2.0 1 1 1 2 2 2 0 Type VI secretion system, TssN adh_short PF00106.25 EOO00932.1 - 6.8e-30 104.0 1.1 9.4e-30 103.5 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO00932.1 - 2.3e-18 66.6 0.5 3e-18 66.3 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EOO00932.1 - 2.4e-13 50.1 0.2 2.9e-13 49.9 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EOO00932.1 - 4.6e-07 29.9 0.0 7.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EOO00932.1 - 1.4e-06 28.3 0.1 3.2e-06 27.2 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EOO00932.1 - 1.9e-06 27.5 0.2 3e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EOO00932.1 - 2.1e-05 23.8 0.2 3.4e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EOO00932.1 - 0.002 17.7 0.1 0.0035 16.9 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 EOO00932.1 - 0.035 14.4 0.1 0.082 13.2 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EOO00932.1 - 0.076 13.3 0.3 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_11 PF08241.12 EOO00933.1 - 4.8e-07 30.3 0.0 8.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO00933.1 - 0.0067 17.1 0.0 0.015 16.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO00933.1 - 0.058 14.1 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CSN4_RPN5_eIF3a PF18420.1 EOO00933.1 - 0.13 12.4 2.0 0.28 11.4 0.6 2.1 2 0 0 2 2 2 0 CSN4/RPN5/eIF3a helix turn helix domain AAA PF00004.29 EOO00934.1 - 2.3e-19 70.1 0.0 6.9e-19 68.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EOO00934.1 - 7.3e-05 23.2 0.0 0.00025 21.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EOO00934.1 - 0.00068 19.4 0.0 0.0032 17.2 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EOO00934.1 - 0.003 17.8 0.2 0.024 14.9 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EOO00934.1 - 0.0054 17.3 0.1 0.18 12.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 EOO00934.1 - 0.024 14.6 0.1 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 EOO00934.1 - 0.047 14.1 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 EOO00934.1 - 0.048 13.8 0.0 0.6 10.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EOO00934.1 - 0.049 13.8 0.0 0.13 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain Nop14 PF04147.12 EOO00935.1 - 2.4 6.3 8.6 2.9 6.0 8.6 1.0 1 0 0 1 1 1 0 Nop14-like family adh_short_C2 PF13561.6 EOO00936.1 - 8.1e-49 166.3 7.0 1.1e-45 156.1 7.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO00936.1 - 1.5e-44 151.8 3.1 1.9e-44 151.5 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO00936.1 - 2.3e-16 60.2 0.7 3.4e-16 59.7 0.7 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EOO00936.1 - 0.0033 17.3 0.4 0.0051 16.7 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EOO00936.1 - 0.041 13.9 0.3 0.068 13.2 0.3 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain SNARE_assoc PF09335.11 EOO00937.1 - 4.4e-18 65.9 10.5 5e-18 65.7 9.0 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein CcmD PF04995.14 EOO00937.1 - 0.13 12.3 0.3 0.13 12.3 0.3 2.7 4 0 0 4 4 4 0 Heme exporter protein D (CcmD) Steroid_dh PF02544.16 EOO00937.1 - 0.19 11.7 3.4 1.6 8.7 0.0 2.6 2 1 0 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase Phage_holin_3_6 PF07332.11 EOO00937.1 - 0.43 10.6 9.7 3.3 7.8 1.6 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III RCR PF12273.8 EOO00937.1 - 0.47 11.1 5.1 0.13 12.9 0.6 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red FixP_N PF14715.6 EOO00937.1 - 0.72 9.6 3.6 2.8 7.7 1.0 2.7 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP SieB PF14163.6 EOO00937.1 - 1.6 8.2 9.6 2.1 7.8 0.1 2.9 3 1 0 3 3 3 0 Super-infection exclusion protein B CbiM PF01891.16 EOO00937.1 - 6.4 6.6 14.3 0.18 11.6 3.7 2.5 2 1 1 3 3 3 0 Cobalt uptake substrate-specific transmembrane region adh_short PF00106.25 EOO00938.1 - 5.4e-27 94.5 0.1 1.3e-25 90.0 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO00938.1 - 1.3e-15 57.6 0.0 1.2e-14 54.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO00938.1 - 8.9e-11 42.0 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 KR domain CoA_binding_2 PF13380.6 EOO00938.1 - 0.042 14.3 0.0 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 CoA binding domain Sacchrp_dh_NADP PF03435.18 EOO00938.1 - 0.087 13.1 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EOO00938.1 - 0.1 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding DUF4853 PF16145.5 EOO00938.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4853) p450 PF00067.22 EOO00939.1 - 4.4e-37 127.9 0.0 4.8e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ATP_bind_1 PF03029.17 EOO00940.1 - 8.4e-73 245.1 0.0 1.2e-72 244.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 EOO00940.1 - 2.6e-06 26.6 0.1 0.0066 15.5 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 EOO00940.1 - 8.6e-06 25.4 0.0 0.0019 17.8 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EOO00940.1 - 3.6e-05 23.6 0.0 7.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EOO00940.1 - 0.00053 20.4 0.0 0.0014 19.0 0.0 1.8 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EOO00940.1 - 0.00097 19.4 0.0 0.0044 17.3 0.0 2.1 2 1 0 2 2 1 1 AAA domain G-alpha PF00503.20 EOO00940.1 - 0.001 18.3 0.0 0.1 11.7 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit NB-ARC PF00931.22 EOO00940.1 - 0.0011 18.2 0.1 0.0042 16.3 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.6 EOO00940.1 - 0.0021 17.8 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EOO00940.1 - 0.0023 18.0 0.0 0.038 14.1 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EOO00940.1 - 0.0025 18.0 0.2 0.0064 16.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain Arf PF00025.21 EOO00940.1 - 0.0029 17.1 0.0 0.7 9.3 0.0 3.1 3 0 0 3 3 3 1 ADP-ribosylation factor family NACHT PF05729.12 EOO00940.1 - 0.0041 17.0 0.0 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain FeoB_N PF02421.18 EOO00940.1 - 0.0051 16.4 0.1 0.2 11.2 0.0 2.8 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_23 PF13476.6 EOO00940.1 - 0.0053 17.3 0.0 2 8.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EOO00940.1 - 0.0074 16.2 0.1 5.9 6.8 0.0 3.2 3 0 0 3 3 3 0 RsgA GTPase Methyltransf_32 PF13679.6 EOO00940.1 - 0.01 15.8 0.2 0.019 15.0 0.2 1.4 1 0 0 1 1 1 0 Methyltransferase domain Zeta_toxin PF06414.12 EOO00940.1 - 0.012 14.9 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 EOO00940.1 - 0.016 14.9 0.0 0.05 13.2 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Roc PF08477.13 EOO00940.1 - 0.016 15.4 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EOO00940.1 - 0.018 14.7 0.1 0.12 11.9 0.1 2.2 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EOO00940.1 - 0.019 14.5 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region PRK PF00485.18 EOO00940.1 - 0.02 14.7 0.0 0.062 13.0 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EOO00940.1 - 0.028 15.0 0.1 0.39 11.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain Thymidylate_kin PF02223.17 EOO00940.1 - 0.047 13.4 1.0 0.28 10.8 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase ATPase_2 PF01637.18 EOO00940.1 - 0.076 12.9 0.1 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 EOO00940.1 - 0.084 12.6 0.0 1.2 8.9 0.0 2.6 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 EOO00940.1 - 0.12 12.4 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EOO00940.1 - 0.13 11.7 0.7 11 5.4 0.0 2.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit BUD22 PF09073.10 EOO00940.1 - 0.23 10.7 15.1 0.37 10.1 15.1 1.2 1 0 0 1 1 1 0 BUD22 DUF1168 PF06658.12 EOO00940.1 - 0.43 10.4 11.9 0.83 9.5 11.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) PPP4R2 PF09184.11 EOO00940.1 - 3.2 7.3 12.9 1.5 8.4 9.6 1.9 2 0 0 2 2 2 0 PPP4R2 Cwf_Cwc_15 PF04889.12 EOO00940.1 - 3.7 7.2 17.1 7.3 6.2 17.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PLDc_2 PF13091.6 EOO00941.1 - 1.3e-15 57.4 0.0 2.7e-07 30.5 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EOO00941.1 - 3.4e-08 33.3 2.1 0.0041 17.2 0.3 3.2 2 1 0 2 2 2 2 Phospholipase D Active site motif FTR1 PF03239.14 EOO00942.1 - 3.6e-60 203.7 5.6 2.1e-58 197.9 5.6 2.0 1 1 0 1 1 1 1 Iron permease FTR1 family DUF3180 PF11377.8 EOO00942.1 - 0.00019 21.6 0.4 0.00019 21.6 0.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3180) CPSase_L_D2 PF02786.17 EOO00943.1 - 3.7e-65 219.4 0.2 5.4e-65 218.8 0.2 1.1 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EOO00943.1 - 9.9e-40 135.5 0.1 7e-39 132.8 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Dala_Dala_lig_C PF07478.13 EOO00943.1 - 1e-11 44.8 0.0 1.9e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EOO00943.1 - 2.5e-05 23.9 0.0 4.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 EOO00943.1 - 0.0019 17.7 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EOO00943.1 - 0.011 15.3 0.0 0.096 12.3 0.0 2.3 1 1 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EOO00943.1 - 0.018 15.1 0.0 0.065 13.3 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp domain CagZ PF09053.10 EOO00944.1 - 0.088 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 CagZ AIG1 PF04548.16 EOO00944.1 - 0.2 11.0 0.1 0.33 10.2 0.1 1.3 1 0 0 1 1 1 0 AIG1 family Sdh_cyt PF01127.22 EOO00945.1 - 8.5e-20 71.0 4.2 1.1e-19 70.7 4.2 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Pkinase PF00069.25 EOO00946.1 - 1.6e-53 181.7 0.0 2.7e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO00946.1 - 9.8e-24 84.0 0.1 5.1e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EOO00946.1 - 0.014 14.3 0.1 0.026 13.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 EOO00946.1 - 0.032 14.2 0.6 0.065 13.1 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 EOO00946.1 - 0.044 13.4 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Sugar_tr PF00083.24 EOO00948.1 - 5.6e-64 216.7 19.3 4.1e-58 197.3 9.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO00948.1 - 1.8e-23 83.1 20.5 3.9e-21 75.4 11.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EOO00948.1 - 0.00018 20.2 0.8 0.00018 20.2 0.8 2.7 3 1 1 4 4 4 2 MFS/sugar transport protein DUF3531 PF12049.8 EOO00948.1 - 0.099 12.6 0.0 16 5.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3531) NmrA PF05368.13 EOO00950.1 - 8e-54 182.7 0.3 9.8e-54 182.4 0.3 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO00950.1 - 1.9e-15 57.3 0.0 3e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EOO00950.1 - 2.8e-07 30.9 0.1 8e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EOO00950.1 - 3.3e-06 26.3 0.0 4.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EOO00950.1 - 0.0002 20.9 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO00950.1 - 0.045 13.2 0.0 0.083 12.3 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 EOO00950.1 - 0.059 13.5 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus EMC1_C PF07774.13 EOO00950.1 - 0.084 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 ER membrane protein complex subunit 1, C-terminal TrkA_N PF02254.18 EOO00950.1 - 0.14 12.4 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain zf-C2H2 PF00096.26 EOO00951.1 - 0.001 19.4 1.0 0.001 19.4 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-ribbon_3 PF13248.6 EOO00951.1 - 0.0045 16.4 1.4 1.3 8.5 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.7 EOO00951.1 - 0.019 15.0 0.5 0.035 14.1 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2_4 PF13894.6 EOO00951.1 - 0.037 14.9 9.3 0.039 14.8 0.8 2.8 3 0 0 3 3 2 0 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 EOO00951.1 - 0.045 14.5 0.1 0.1 13.4 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon family DUF5448 PF17526.2 EOO00951.1 - 0.046 13.9 0.1 0.061 13.5 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5448) zinc_ribbon_4 PF13717.6 EOO00951.1 - 0.049 13.6 1.8 2.2 8.3 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EOO00951.1 - 0.089 12.9 1.9 0.25 11.5 1.9 1.8 1 1 0 1 1 1 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 EOO00951.1 - 0.12 12.4 1.1 0.29 11.1 1.1 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain RVT_2 PF07727.14 EOO00951.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf_C2H2_ZHX PF18387.1 EOO00951.1 - 0.96 9.1 4.2 0.74 9.5 0.6 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-LSD1 PF06943.12 EOO00951.1 - 1.2 9.1 5.9 7.5 6.5 0.7 2.3 2 0 0 2 2 2 0 LSD1 zinc finger zf-C2HC_2 PF13913.6 EOO00951.1 - 2.4 8.2 5.5 8.5 6.4 0.5 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn_Tnp_IS1595 PF12760.7 EOO00951.1 - 2.6 8.1 5.2 7.8 6.6 2.3 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain SEP PF08059.13 EOO00952.1 - 1.4e-23 83.2 0.5 3.3e-23 82.0 0.0 2.0 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 EOO00952.1 - 3.5e-11 43.1 0.0 7.6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EOO00952.1 - 8e-11 41.6 0.5 1.3e-10 40.9 0.5 1.3 1 0 0 1 1 1 1 UBA-like domain BUD22 PF09073.10 EOO00952.1 - 4.3 6.6 12.5 6.7 5.9 12.5 1.2 1 0 0 1 1 1 0 BUD22 Glycos_transf_2 PF00535.26 EOO00953.1 - 2.5e-36 125.0 0.0 3e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EOO00953.1 - 1.4e-14 54.5 0.0 1.9e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EOO00953.1 - 3.6e-06 26.7 0.0 4.7e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EOO00953.1 - 1.2e-05 24.9 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_4 PF13439.6 EOO00953.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 DUF4471 PF14740.6 EOO00953.1 - 0.22 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Peptidase_S9 PF00326.21 EOO00954.1 - 5.3e-43 147.0 0.0 7.5e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 EOO00954.1 - 2.2e-06 27.5 0.2 0.012 15.5 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Hydrolase_4 PF12146.8 EOO00954.1 - 7.3e-06 25.4 0.1 0.0015 17.8 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 EOO00954.1 - 8.3e-06 25.9 0.0 7.9e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EOO00954.1 - 4e-05 23.3 0.0 0.00016 21.3 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EOO00954.1 - 0.00074 19.2 0.0 0.16 11.6 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EOO00954.1 - 0.0039 16.9 0.1 0.13 11.9 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EOO00954.1 - 0.0041 17.0 0.0 0.094 12.5 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EOO00954.1 - 0.0071 16.0 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Ribosomal_L12 PF00542.19 EOO00955.1 - 0.017 15.5 0.4 0.033 14.5 0.4 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain MFS_1 PF07690.16 EOO00957.1 - 3.6e-32 111.7 27.8 3.6e-32 111.7 27.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EOO00957.1 - 1e-06 28.3 3.3 1e-06 28.3 3.3 2.4 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB RhoGAP PF00620.27 EOO00958.1 - 5.1e-17 62.1 0.0 1.3e-16 60.8 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain Helo_like_N PF17111.5 EOO00958.1 - 1.9e-05 24.1 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DEAD PF00270.29 EOO00959.1 - 6.2e-43 146.6 0.2 1e-42 145.9 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EOO00959.1 - 2.7e-33 114.6 0.0 9.7e-33 112.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EOO00959.1 - 0.00044 20.0 0.1 0.00065 19.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EOO00959.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EOO00959.1 - 0.0015 18.9 0.1 0.012 16.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 EOO00959.1 - 0.058 13.4 0.2 0.2 11.7 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 EOO00959.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 EOO00959.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase DUF5393 PF17371.2 EOO00959.1 - 0.076 11.1 0.1 0.12 10.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) AAA_22 PF13401.6 EOO00959.1 - 0.15 12.3 1.0 0.68 10.2 1.0 2.0 1 1 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.25 EOO00960.1 - 3.7e-07 30.4 0.0 5.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EOO00960.1 - 2e-06 27.7 0.0 8.6e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EOO00960.1 - 1.7e-05 25.1 0.0 4.4e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EOO00960.1 - 0.05 13.7 0.1 0.27 11.3 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.7 EOO00961.1 - 3.3e-14 54.0 0.0 4.2e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EOO00961.1 - 9.5e-12 45.1 0.0 4.6e-07 29.7 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EOO00961.1 - 2.8e-06 26.8 0.0 0.0016 17.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 CBX7_C PF17218.3 EOO00962.1 - 0.033 13.9 0.5 0.078 12.7 0.5 1.6 1 0 0 1 1 1 0 CBX family C-terminal motif DUF3449 PF11931.8 EOO00963.1 - 7.9e-78 260.5 3.6 2.5e-77 258.9 0.2 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EOO00963.1 - 9.4e-27 93.4 0.4 2.1e-26 92.2 0.4 1.6 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EOO00963.1 - 2.9e-12 46.2 0.2 6.1e-12 45.2 0.2 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 EOO00963.1 - 3.6e-10 39.9 2.2 1.8e-07 31.3 0.6 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EOO00963.1 - 4.6e-10 39.5 3.5 3.3e-08 33.6 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding PRP9_N PF16958.5 EOO00963.1 - 0.00045 20.3 13.9 0.031 14.3 0.4 3.5 3 1 1 4 4 4 2 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_2 PF12756.7 EOO00963.1 - 0.0009 19.5 0.7 0.026 14.8 0.2 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 EOO00963.1 - 0.021 15.0 0.4 0.021 15.0 0.4 2.8 2 1 0 2 2 2 0 DBF zinc finger CmlA_N PF18456.1 EOO00963.1 - 0.06 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Diiron non-heme beta-hydroxylase N-terminal domain zf-C2H2_4 PF13894.6 EOO00963.1 - 0.074 13.9 1.4 18 6.5 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Tom5 PF10642.9 EOO00964.1 - 0.072 13.1 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase FAD_binding_3 PF01494.19 EOO00965.1 - 3.4e-26 92.3 0.0 6.9e-26 91.3 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Phage_TTP_13 PF16463.5 EOO00965.1 - 0.11 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Phage tail tube protein family Glyco_hydro_7 PF00840.20 EOO00966.1 - 3.2e-198 658.8 21.3 4e-198 658.5 21.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 EOO00966.1 - 4.8e-13 48.8 12.5 4.8e-13 48.8 12.5 4.5 4 1 0 4 4 4 2 Fungal cellulose binding domain MFS_1 PF07690.16 EOO00968.1 - 4.7e-22 78.4 30.3 4.7e-22 78.4 30.3 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily PRTase_2 PF15609.6 EOO00968.1 - 0.064 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase BacteriocIIc_cy PF12173.8 EOO00968.1 - 0.5 10.6 3.5 0.26 11.6 0.6 2.1 2 0 0 2 2 2 0 Bacteriocin class IIc cyclic gassericin A-like PD40 PF07676.12 EOO00969.1 - 3e-43 144.9 21.9 4.4e-08 32.8 0.2 9.7 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 EOO00969.1 - 2.8e-13 49.3 1.8 0.031 13.0 0.0 7.1 4 2 3 7 7 7 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF5050 PF16472.5 EOO00969.1 - 0.022 14.0 0.0 8.7 5.5 0.0 3.7 3 2 0 3 3 3 0 Domain of unknown function (DUF5050) Gmad1 PF10647.9 EOO00969.1 - 0.088 12.5 1.6 2.4 7.8 0.1 3.4 3 1 1 4 4 4 0 Lipoprotein LpqB beta-propeller domain DUF1513 PF07433.11 EOO00969.1 - 0.11 11.5 0.0 30 3.6 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1513) MFS_1 PF07690.16 EOO00970.1 - 3.6e-18 65.6 50.6 1.4e-16 60.4 47.5 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily SGS PF05002.15 EOO00971.1 - 1.4e-28 98.8 4.9 1.4e-28 98.8 4.9 2.1 2 0 0 2 2 2 1 SGS domain CS PF04969.16 EOO00971.1 - 4.6e-07 30.8 0.0 8.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 EOO00971.1 - 1.1e-06 28.3 5.3 0.13 12.4 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EOO00971.1 - 8.1e-06 25.4 3.0 1.6 8.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EOO00971.1 - 0.0017 19.0 10.8 0.0031 18.1 5.9 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EOO00971.1 - 0.0027 18.2 4.9 0.019 15.5 0.8 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EOO00971.1 - 0.01 16.0 0.9 0.098 12.9 0.1 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EOO00971.1 - 0.031 14.5 5.5 2.3 8.6 1.7 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EOO00971.1 - 0.063 13.4 0.8 0.15 12.2 0.8 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 EOO00971.1 - 0.081 12.6 1.2 0.28 10.9 0.2 2.3 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.6 EOO00971.1 - 0.12 12.7 1.0 27 5.3 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EOO00971.1 - 0.2 11.8 2.2 8.3 6.7 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EOO00971.1 - 0.58 10.9 5.4 35 5.3 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EOO00971.1 - 1.3 10.0 4.8 22 6.2 0.3 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Peptidase_M49 PF03571.15 EOO00972.1 - 1.8e-85 287.4 0.0 3.5e-76 256.7 0.0 2.0 1 1 1 2 2 2 2 Peptidase family M49 PAN_4 PF14295.6 EOO00973.1 - 3.4e-06 26.9 0.1 1.1e-05 25.2 0.1 1.9 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 EOO00973.1 - 9.1e-05 22.3 0.1 0.00031 20.7 0.1 1.9 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 EOO00973.1 - 0.06 13.2 0.7 0.21 11.4 0.7 1.9 1 0 0 1 1 1 0 PAN-like domain Transformer PF06495.11 EOO00973.1 - 0.076 13.1 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein TAF6_C PF07571.13 EOO00975.1 - 5.6e-28 97.1 0.0 1.2e-27 96.1 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EOO00975.1 - 5.8e-22 77.7 0.0 1.7e-21 76.2 0.0 1.8 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EOO00975.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EOO00975.1 - 0.03 14.7 0.1 0.052 13.9 0.1 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TauD PF02668.16 EOO00976.1 - 6.9e-43 147.4 0.0 8.4e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EOO00976.1 - 0.0038 16.4 0.0 0.0073 15.5 0.0 1.4 1 0 0 1 1 1 1 CsiD 2OG-FeII_Oxy_3 PF13640.6 EOO00976.1 - 0.098 13.6 0.1 2.1 9.3 0.0 2.2 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 EOO00976.1 - 0.16 12.2 0.1 0.95 9.7 0.0 2.1 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Hpre_diP_synt_I PF07456.11 EOO00978.1 - 0.032 14.2 0.1 0.032 14.2 0.1 1.9 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase component I CFEM PF05730.11 EOO00979.1 - 2.2e-08 34.1 6.1 3.7e-08 33.4 6.1 1.4 1 0 0 1 1 1 1 CFEM domain Ecl1 PF12855.7 EOO00979.1 - 0.39 11.8 14.9 0.56 11.4 14.9 1.1 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins PRCC PF10253.9 EOO00979.1 - 0.9 10.3 8.8 1.5 9.5 8.8 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Retinal PF15449.6 EOO00979.1 - 2.6 5.7 21.6 3.2 5.4 21.6 1.0 1 0 0 1 1 1 0 Retinal protein TFIIA PF03153.13 EOO00979.1 - 6.3 6.7 6.9 8.1 6.3 6.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 EOO00979.1 - 6.6 5.8 12.5 7.3 5.7 12.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Fungal_trans PF04082.18 EOO00980.1 - 5e-50 170.0 0.0 7.3e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EOO00980.1 - 0.00051 20.3 0.3 0.00051 20.3 0.3 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EOO00980.1 - 0.42 11.6 0.2 0.42 11.6 0.2 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger Cu-oxidase_2 PF07731.14 EOO00981.1 - 1.3e-42 144.8 2.0 3e-39 133.9 0.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EOO00981.1 - 2.8e-37 128.3 1.1 1.2e-34 119.7 0.1 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EOO00981.1 - 2.5e-18 66.2 4.8 4.7e-15 55.6 0.3 3.4 3 1 0 3 3 3 2 Multicopper oxidase DUF5060 PF16586.5 EOO00981.1 - 0.0078 16.6 0.0 0.026 14.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5060) Nop10p PF04135.12 EOO00983.1 - 8.9e-19 67.3 0.0 1e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Abhydrolase_6 PF12697.7 EOO00984.1 - 4e-11 44.0 0.0 6.4e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EOO00984.1 - 1.1e-08 35.0 0.0 2.5e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EOO00984.1 - 1.4e-05 24.5 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2157 PF09925.9 EOO00985.1 - 0.84 9.4 5.9 1.2 8.9 5.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) UbiA PF01040.18 EOO00986.1 - 8.7e-58 195.6 22.9 8.7e-58 195.6 22.9 1.9 1 1 1 2 2 2 1 UbiA prenyltransferase family IQCJ-SCHIP1 PF15157.6 EOO00986.1 - 0.28 11.0 0.9 0.47 10.3 0.9 1.3 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif DUF3040 PF11239.8 EOO00986.1 - 10 6.5 7.8 8.9 6.7 2.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Glyco_tranf_2_3 PF13641.6 EOO00987.1 - 1.9e-21 77.0 0.0 2.4e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EOO00987.1 - 8.3e-08 32.2 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EOO00987.1 - 7.1e-06 25.6 0.0 7.2e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 EOO00987.1 - 0.027 14.4 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 p450 PF00067.22 EOO00988.1 - 9.7e-47 159.7 0.0 1.3e-46 159.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LPMO_10 PF03067.15 EOO00989.1 - 2.2e-10 41.5 0.2 4.7e-10 40.4 0.2 1.5 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Astro_capsid_p PF12226.8 EOO00989.1 - 0.29 10.3 4.8 0.41 9.8 4.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Amidoligase_2 PF12224.8 EOO00990.1 - 6.3e-19 68.6 0.0 7e-12 45.6 0.0 2.2 1 1 0 2 2 2 2 Putative amidoligase enzyme SQHop_cyclase_C PF13243.6 EOO00991.1 - 1.5e-46 159.0 1.8 1.2e-45 156.0 0.5 2.5 2 1 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EOO00991.1 - 3.7e-37 128.0 4.9 1.3e-32 113.1 1.2 3.3 3 0 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EOO00991.1 - 2.6e-27 94.2 8.6 1.8e-08 34.0 0.0 4.1 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 EOO00991.1 - 0.0018 17.4 1.5 0.04 12.9 0.2 3.0 2 2 2 4 4 4 1 A-macroglobulin TED domain Pec_lyase PF09492.10 EOO00991.1 - 0.012 15.0 1.1 0.67 9.2 0.0 3.6 5 0 0 5 5 5 0 Pectic acid lyase Sugar_tr PF00083.24 EOO00992.1 - 2.3e-47 161.9 9.1 2.6e-47 161.7 9.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO00992.1 - 2.3e-06 26.8 10.9 3.7e-06 26.1 10.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Aldo_ket_red PF00248.21 EOO00995.1 - 5.9e-49 166.8 0.0 4.4e-48 164.0 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family TrmB PF01978.19 EOO00995.1 - 0.074 13.0 0.0 1.1 9.1 0.0 2.9 4 0 0 4 4 4 0 Sugar-specific transcriptional regulator TrmB ADH_zinc_N PF00107.26 EOO00996.1 - 1e-07 32.0 1.2 2e-07 31.0 0.4 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EOO00996.1 - 1.5e-07 31.3 0.0 3.7e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_4 PF08386.10 EOO00997.1 - 4.7e-20 71.6 0.1 9.4e-20 70.6 0.1 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 EOO00997.1 - 1.3e-19 70.9 0.0 1.2e-14 54.5 0.0 2.8 2 1 0 2 2 2 2 alpha/beta hydrolase fold ADH_N PF08240.12 EOO00998.1 - 1.2e-07 31.6 0.1 1.4e-06 28.1 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EOO00998.1 - 2.1e-06 28.8 0.0 6.3e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EOO00998.1 - 5.1e-06 26.5 0.1 5e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Dioxygenase_C PF00775.21 EOO01000.1 - 4.8e-05 22.9 0.1 0.00059 19.3 0.1 2.2 1 1 0 1 1 1 1 Dioxygenase SpaA PF17802.1 EOO01000.1 - 0.0052 17.1 0.1 0.014 15.7 0.0 1.7 1 1 0 1 1 1 1 Prealbumin-like fold domain MFS_1 PF07690.16 EOO01001.1 - 2.6e-38 131.9 30.0 2.6e-38 131.9 30.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1688 PF07958.11 EOO01002.1 - 9.9e-177 587.9 0.0 1.2e-176 587.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) OTT_1508_deam PF14441.6 EOO01003.1 - 0.00087 19.2 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase PLU-1 PF08429.11 EOO01004.1 - 9.9e-115 383.3 17.2 3.4e-111 371.7 16.0 2.4 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 EOO01004.1 - 3.8e-41 140.1 0.1 9.9e-41 138.8 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 EOO01004.1 - 6.7e-21 74.8 0.1 2.2e-20 73.1 0.1 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 EOO01004.1 - 1.3e-17 63.4 25.7 9e-11 41.5 5.8 2.8 3 0 0 3 3 2 2 PHD-finger JmjN PF02375.17 EOO01004.1 - 3.1e-15 55.8 1.8 8e-15 54.5 1.8 1.8 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 EOO01004.1 - 0.00037 20.7 6.0 0.15 12.3 1.7 2.6 2 0 0 2 2 2 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EOO01004.1 - 0.0015 18.7 5.2 0.57 10.4 1.1 2.5 2 0 0 2 2 2 2 PHD-zinc-finger like domain C1_1 PF00130.22 EOO01004.1 - 0.014 15.3 11.1 0.55 10.2 4.1 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Chloroplast_duf PF14476.6 EOO01004.1 - 0.43 9.5 2.4 0.5 9.3 0.2 1.9 2 0 0 2 2 2 0 Petal formation-expressed zf-PHD-like PF15446.6 EOO01004.1 - 0.73 9.4 12.7 1.2 8.7 2.4 3.3 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-RING_2 PF13639.6 EOO01004.1 - 1.5 9.2 20.5 2 8.8 6.2 2.6 2 0 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.7 EOO01004.1 - 8.5 6.8 15.4 0.15 12.3 3.4 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain PHD_4 PF16866.5 EOO01004.1 - 8.9 6.5 20.3 2 8.6 6.8 2.8 2 0 0 2 2 2 0 PHD-finger Glyco_hydro_28 PF00295.17 EOO01005.1 - 3.1e-26 92.2 6.2 3.9e-26 91.9 6.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Sugar_tr PF00083.24 EOO01006.1 - 4.1e-101 339.1 21.1 4.7e-101 338.9 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO01006.1 - 6.1e-29 101.1 28.2 9.2e-23 80.7 5.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2615 PF11027.8 EOO01006.1 - 0.43 10.7 3.3 8.3 6.6 0.4 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2615) OATP PF03137.20 EOO01006.1 - 7.5 4.7 13.6 0.19 10.0 3.7 2.9 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TPR_9 PF13371.6 EOO01007.1 - 0.014 15.5 0.0 0.046 13.9 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4685 PF15737.5 EOO01007.1 - 2.7 8.5 6.3 3.5 8.1 0.0 3.7 4 1 1 5 5 5 0 Domain of unknown function (DUF4685) Beta_elim_lyase PF01212.21 EOO01008.1 - 0.083 12.1 2.3 0.084 12.1 0.1 2.1 2 1 0 3 3 3 0 Beta-eliminating lyase p450 PF00067.22 EOO01009.1 - 1.4e-07 30.6 0.0 1.6e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 EOO01011.1 - 1e-10 41.4 0.1 1.2e-09 37.9 0.1 2.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EOO01011.1 - 3.2e-05 23.3 0.1 0.006 15.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EOO01011.1 - 7.2e-05 22.9 0.1 0.00016 21.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EOO01011.1 - 8e-05 23.1 0.0 0.0035 17.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EOO01011.1 - 9e-05 21.8 0.0 0.097 11.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EOO01011.1 - 0.0013 18.3 0.1 0.015 14.9 0.1 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase SecA_SW PF07516.13 EOO01011.1 - 0.018 15.1 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 SecA Wing and Scaffold domain TrkA_N PF02254.18 EOO01011.1 - 0.028 14.7 0.0 0.07 13.4 0.1 1.6 2 0 0 2 2 1 0 TrkA-N domain Lycopene_cycl PF05834.12 EOO01011.1 - 0.046 12.8 0.1 0.14 11.2 0.1 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 EOO01011.1 - 0.061 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EOO01011.1 - 0.064 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 EOO01011.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain p450 PF00067.22 EOO01012.1 - 3.8e-38 131.4 0.0 4.5e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DAO PF01266.24 EOO01013.1 - 1.3e-20 74.3 0.0 1.6e-20 74.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EOO01013.1 - 0.0012 18.0 0.0 0.008 15.3 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A ApbA PF02558.16 EOO01013.1 - 0.0018 17.9 0.4 0.003 17.2 0.4 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EOO01013.1 - 0.0076 16.1 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EOO01013.1 - 0.0096 16.1 0.1 0.021 15.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EOO01013.1 - 0.014 14.6 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EOO01013.1 - 0.015 14.4 0.0 0.21 10.7 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 EOO01013.1 - 0.057 12.5 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EOO01013.1 - 0.077 13.6 0.6 0.15 12.7 0.6 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF5581 PF17744.1 EOO01013.1 - 0.2 11.0 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5581) ADH_zinc_N PF00107.26 EOO01014.1 - 6.7e-19 68.2 0.0 1e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EOO01014.1 - 1.7e-11 45.3 0.0 2.8e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EOO01014.1 - 0.016 15.1 0.0 0.084 12.8 0.0 2.2 3 0 0 3 3 3 0 N-terminal domain of oxidoreductase Semialdhyde_dh PF01118.24 EOO01014.1 - 0.018 15.5 0.1 0.084 13.3 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_C PF02080.21 EOO01014.1 - 0.025 14.4 0.1 0.44 10.4 0.1 2.3 2 0 0 2 2 2 0 TrkA-C domain DapB_N PF01113.20 EOO01014.1 - 0.077 13.1 0.3 0.29 11.3 0.3 2.0 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ELFV_dehydrog PF00208.21 EOO01014.1 - 0.11 12.2 0.2 0.18 11.5 0.2 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase adh_short PF00106.25 EOO01014.1 - 0.13 11.7 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Aminotran_3 PF00202.21 EOO01015.1 - 1.1e-51 175.8 0.1 2.4e-51 174.7 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class-III Glyco_hydro_1 PF00232.18 EOO01016.1 - 3.2e-70 236.8 0.2 5.4e-68 229.5 0.2 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Aldo_ket_red PF00248.21 EOO01017.1 - 9e-26 90.7 0.0 3.5e-18 65.8 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family NAD_binding_10 PF13460.6 EOO01018.1 - 1.8e-14 54.1 0.0 2.8e-14 53.4 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EOO01018.1 - 2.6e-14 53.4 0.0 3.7e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EOO01018.1 - 1.3e-07 31.3 0.0 1.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EOO01018.1 - 0.00059 19.0 0.1 0.0017 17.6 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 EOO01018.1 - 0.04 13.8 0.0 0.082 12.8 0.0 1.6 1 1 0 1 1 1 0 KR domain DapB_N PF01113.20 EOO01018.1 - 0.054 13.6 0.3 0.12 12.5 0.3 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EOO01018.1 - 0.073 13.5 0.1 0.11 13.0 0.1 1.4 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 EOO01018.1 - 0.093 13.0 0.1 0.22 11.8 0.1 1.7 1 1 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EOO01018.1 - 0.12 12.7 0.1 0.27 11.5 0.1 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sugar_tr PF00083.24 EOO01019.1 - 6e-108 361.6 17.6 7e-108 361.4 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO01019.1 - 1.8e-27 96.2 34.3 7.6e-21 74.4 13.2 2.5 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 EOO01019.1 - 6.6e-08 31.4 1.2 6.6e-08 31.4 1.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EOO01021.1 - 1.7e-100 337.1 17.3 6.2e-94 315.4 13.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO01021.1 - 3.5e-21 75.5 25.9 2e-20 73.0 22.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.12 EOO01023.1 - 1.3e-15 57.2 0.0 4.8e-15 55.4 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EOO01023.1 - 2.2e-08 34.1 0.2 2.3e-07 30.9 0.2 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EOO01023.1 - 8.1e-07 28.7 0.0 1.5e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Cupin_2 PF07883.11 EOO01023.1 - 0.045 13.5 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Cupin domain FAD_binding_2 PF00890.24 EOO01023.1 - 0.06 12.4 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 EOO01023.1 - 0.067 12.5 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 EOO01023.1 - 0.081 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EOO01023.1 - 0.12 11.0 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_10 PF13460.6 EOO01024.1 - 3.3e-08 33.6 1.8 0.00011 22.2 0.0 2.1 1 1 1 2 2 2 2 NAD(P)H-binding DMRT-like PF15791.5 EOO01024.1 - 0.038 14.4 0.1 0.051 14.0 0.1 1.2 1 0 0 1 1 1 0 Doublesex-and mab-3-related transcription factor C1 and C2 NAD_binding_10 PF13460.6 EOO01025.1 - 4.9e-08 33.1 0.0 8.1e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding AA_permease_2 PF13520.6 EOO01026.1 - 1.7e-37 129.3 34.2 2e-37 129.0 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EOO01026.1 - 3.8e-12 45.5 32.0 4.6e-12 45.3 32.0 1.1 1 0 0 1 1 1 1 Amino acid permease Aldo_ket_red PF00248.21 EOO01027.1 - 6.6e-60 202.8 0.0 8.2e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_15 PF09445.10 EOO01027.1 - 0.16 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase FAD_binding_4 PF01565.23 EOO01028.1 - 3e-19 69.1 2.6 3e-19 69.1 2.6 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EOO01028.1 - 2.6e-08 33.8 0.2 7e-08 32.5 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_3 PF01494.19 EOO01029.1 - 1.4e-12 47.5 0.2 8.9e-09 35.0 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 EOO01029.1 - 6.5e-07 29.3 0.1 8.7e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EOO01029.1 - 2.4e-06 27.7 0.6 5.3e-06 26.6 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EOO01029.1 - 3.4e-05 23.1 0.1 4.8e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EOO01029.1 - 7.4e-05 22.1 0.1 0.0001 21.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EOO01029.1 - 0.0017 17.8 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EOO01029.1 - 0.0018 18.8 0.9 0.0048 17.4 0.9 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EOO01029.1 - 0.015 14.4 3.7 0.032 13.3 3.7 1.5 1 1 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EOO01029.1 - 0.07 12.2 0.7 0.11 11.6 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 EOO01029.1 - 0.13 11.6 0.1 0.26 10.5 0.1 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EOO01029.1 - 0.22 10.2 1.2 0.32 9.6 1.2 1.2 1 0 0 1 1 1 0 HI0933-like protein TRP PF06011.12 EOO01029.1 - 0.25 10.0 0.1 0.35 9.5 0.1 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel 3HCDH_N PF02737.18 EOO01029.1 - 0.28 11.1 0.9 0.53 10.1 0.9 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HpcH_HpaI PF03328.14 EOO01030.1 - 4.1e-33 114.4 0.1 4.9e-33 114.1 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Integrase_Zn PF02022.19 EOO01030.1 - 0.037 14.0 0.2 0.069 13.1 0.2 1.4 1 0 0 1 1 1 0 Integrase Zinc binding domain MFS_1 PF07690.16 EOO01032.1 - 5.2e-32 111.2 27.8 5.2e-32 111.2 27.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Cytochrom_B_C PF00032.17 EOO01032.1 - 0.14 12.5 6.9 18 5.7 0.1 3.8 3 1 1 4 4 4 0 Cytochrome b(C-terminal)/b6/petD RseC_MucC PF04246.12 EOO01032.1 - 0.24 11.3 0.1 0.24 11.3 0.1 3.1 4 0 0 4 4 4 0 Positive regulator of sigma(E), RseC/MucC Wzz PF02706.15 EOO01032.1 - 2.7 8.4 7.3 8.4 6.8 0.3 2.9 2 1 1 3 3 3 0 Chain length determinant protein ADH_zinc_N PF00107.26 EOO01033.1 - 1.4e-18 67.1 0.0 2.1e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EOO01033.1 - 2.6e-17 62.7 3.6 9.2e-17 60.9 2.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EOO01033.1 - 2.4e-08 33.7 0.0 0.00039 20.0 0.0 2.5 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EOO01033.1 - 5.4e-05 24.2 0.0 0.00011 23.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPM_phosphatase PF04536.14 EOO01033.1 - 0.018 15.2 0.0 0.067 13.4 0.0 1.8 2 0 0 2 2 2 0 TPM domain WD40 PF00400.32 EOO01034.1 - 2.6e-10 40.7 6.9 0.12 13.3 0.0 5.1 4 0 0 4 4 4 4 WD domain, G-beta repeat RPE65 PF03055.15 EOO01035.1 - 1.5e-98 331.0 0.0 2.4e-98 330.4 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SnoaL_4 PF13577.6 EOO01035.1 - 5.8e-29 100.8 1.1 1.7e-28 99.3 0.3 2.2 2 0 0 2 2 2 1 SnoaL-like domain CHAP PF05257.16 EOO01035.1 - 0.034 14.7 0.3 0.14 12.8 0.3 2.2 1 0 0 1 1 1 0 CHAP domain PPR_2 PF13041.6 EOO01036.1 - 0.0045 17.1 0.5 0.017 15.3 0.0 2.1 4 0 0 4 4 4 1 PPR repeat family PPR PF01535.20 EOO01036.1 - 0.3 11.4 2.2 6.9 7.2 0.3 3.6 3 1 0 3 3 3 0 PPR repeat Epimerase PF01370.21 EOO01037.1 - 6.2e-16 58.6 0.1 2.5e-15 56.6 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EOO01037.1 - 1.1e-09 37.8 0.0 1.4e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EOO01037.1 - 4.9e-08 32.7 0.2 3.3e-07 30.0 0.1 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EOO01037.1 - 8.7e-08 31.6 0.0 0.0035 16.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EOO01037.1 - 1.1e-05 25.4 0.0 2.6e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EOO01037.1 - 2.2e-05 24.0 0.1 0.00084 18.8 0.0 2.6 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EOO01037.1 - 3.4e-05 23.1 0.4 0.048 12.8 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.13 EOO01037.1 - 0.0019 17.8 0.1 0.0046 16.6 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 EOO01037.1 - 0.0021 17.3 0.0 0.0043 16.2 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EOO01037.1 - 0.063 13.2 0.1 0.15 12.0 0.1 1.6 1 1 0 1 1 1 0 KR domain Abhydrolase_1 PF00561.20 EOO01038.1 - 6.8e-21 75.1 0.0 2.6e-19 69.9 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EOO01038.1 - 2.8e-18 65.9 0.0 5.4e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein AA_permease PF00324.21 EOO01039.1 - 7e-121 404.1 32.3 7.9e-121 404.0 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EOO01039.1 - 3.1e-30 105.4 36.4 3.8e-30 105.1 36.4 1.0 1 0 0 1 1 1 1 Amino acid permease GRAM PF02893.20 EOO01040.1 - 2.2e-34 117.7 2.8 1.5e-20 73.2 0.0 3.3 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 EOO01040.1 - 2.2e-28 99.0 0.0 4.5e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 EOO01040.1 - 5.7e-13 49.3 0.0 2e-12 47.6 0.0 2.0 1 0 0 1 1 1 1 PH domain UDPGT PF00201.18 EOO01040.1 - 0.00015 20.7 0.0 0.00033 19.6 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.6 EOO01040.1 - 0.00017 21.8 0.0 0.00041 20.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 EOO01040.1 - 0.00076 19.6 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EOO01040.1 - 0.0018 18.7 0.2 0.045 14.2 0.2 2.9 1 1 0 1 1 1 1 Pleckstrin homology domain PBP1_TM PF14812.6 EOO01040.1 - 7.7 7.0 8.6 6 7.3 1.3 3.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal 2-Hacid_dh_C PF02826.19 EOO01041.1 - 4.3e-44 150.0 0.0 1.8e-29 102.4 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EOO01041.1 - 0.035 14.7 0.0 0.094 13.3 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EOO01041.1 - 0.044 13.7 0.0 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 EOO01041.1 - 0.045 14.3 0.0 0.077 13.5 0.0 1.5 1 1 0 1 1 1 0 XdhC Rossmann domain ApbA PF02558.16 EOO01041.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 EOO01041.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Beta_helix PF13229.6 EOO01042.1 - 5.4e-12 45.8 16.8 3.2e-10 40.1 11.6 3.0 1 1 1 3 3 3 2 Right handed beta helix region Chondroitinas_B PF14592.6 EOO01042.1 - 1.3e-07 30.9 0.0 3.2e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Chondroitinase B DUF1565 PF07602.11 EOO01042.1 - 5e-05 22.7 7.0 7.2e-05 22.2 0.4 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1565) DUF2470 PF10615.9 EOO01043.1 - 1.2e-21 77.1 0.5 1.7e-21 76.6 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) ATP-synt_C PF00137.21 EOO01044.1 - 2.5e-34 117.4 35.7 1.2e-21 76.8 16.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Tetraspanin PF00335.20 EOO01044.1 - 5.5 6.6 7.3 9.6 5.8 7.3 1.4 1 0 0 1 1 1 0 Tetraspanin family Methyltransf_34 PF11312.8 EOO01045.1 - 1.7e-106 355.9 0.0 1.9e-106 355.7 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Sugar_tr PF00083.24 EOO01046.1 - 1.7e-68 231.5 16.2 1.9e-68 231.4 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO01046.1 - 4e-25 88.5 42.5 3e-24 85.6 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EOO01046.1 - 0.021 13.2 6.2 0.0057 15.1 3.1 1.5 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF2150 PF09920.9 EOO01047.1 - 0.067 13.2 0.4 0.2 11.6 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) Atx10homo_assoc PF09759.9 EOO01047.1 - 0.19 11.7 1.6 16 5.6 0.0 3.6 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain LSM PF01423.22 EOO01048.1 - 1.5e-14 53.4 0.5 1.7e-14 53.2 0.5 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EOO01048.1 - 0.013 15.1 0.1 0.019 14.6 0.1 1.4 1 0 0 1 1 1 0 Hfq protein PhnA PF03831.14 EOO01048.1 - 0.02 14.8 0.1 0.25 11.3 0.0 2.2 2 0 0 2 2 2 0 PhnA domain ICE2 PF08426.10 EOO01049.1 - 1.5e-167 557.8 7.7 1.7e-167 557.7 7.7 1.0 1 0 0 1 1 1 1 ICE2 Ribosomal_L7Ae PF01248.26 EOO01050.1 - 1.6e-26 91.8 0.1 2e-26 91.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EOO01050.1 - 0.01 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain TetR_C_28 PF17937.1 EOO01050.1 - 0.051 14.0 0.2 0.34 11.4 0.1 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Herpes_UL51 PF04540.13 EOO01050.1 - 0.065 13.0 0.1 0.078 12.7 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL51 protein Mur_ligase_M PF08245.12 EOO01051.1 - 1.6e-06 28.2 0.1 2.8e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Mur ligase middle domain DUF218 PF02698.17 EOO01051.1 - 6.8e-05 22.9 0.2 0.0095 16.0 0.1 2.8 2 1 0 2 2 2 1 DUF218 domain Mur_ligase_C PF02875.21 EOO01051.1 - 0.073 13.3 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain ERG4_ERG24 PF01222.17 EOO01052.1 - 2.7e-134 448.2 22.1 3.3e-134 447.9 22.1 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Syja_N PF02383.18 EOO01053.1 - 1.9e-95 319.9 0.0 2.9e-95 319.3 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 EOO01053.1 - 2.1e-40 137.0 0.1 4.7e-40 135.9 0.1 1.6 1 0 0 1 1 1 1 Inositol phosphatase Pkinase PF00069.25 EOO01054.1 - 1.2e-05 24.8 0.0 1.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO01054.1 - 0.047 13.0 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Macoilin PF09726.9 EOO01055.1 - 4.8 5.6 16.2 6.2 5.3 16.2 1.3 1 0 0 1 1 1 0 Macoilin family Transketolase_N PF00456.21 EOO01056.1 - 5.9e-156 518.6 0.0 8.3e-156 518.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EOO01056.1 - 2.5e-44 151.1 0.0 4e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EOO01056.1 - 1.8e-11 44.0 0.0 3.8e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EOO01056.1 - 0.00024 20.4 0.1 0.00036 19.8 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase COesterase PF00135.28 EOO01057.1 - 1.5e-76 258.4 0.0 1.8e-76 258.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EOO01057.1 - 7.5e-06 25.9 0.0 0.0032 17.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold CP_ATPgrasp_2 PF14403.6 EOO01059.1 - 3.5e-112 375.0 0.0 4.5e-112 374.7 0.0 1.1 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 EOO01059.1 - 7.9e-80 268.4 0.0 1e-79 268.0 0.0 1.2 1 0 0 1 1 1 1 A circularly permuted ATPgrasp ATPgrasp_YheCD PF14398.6 EOO01059.1 - 0.19 10.9 0.0 2.6 7.2 0.0 2.1 1 1 0 1 1 1 0 YheC/D like ATP-grasp FliT PF05400.13 EOO01059.1 - 0.31 11.9 1.8 10 7.0 0.3 2.6 2 0 0 2 2 2 0 Flagellar protein FliT 2OG-FeII_Oxy PF03171.20 EOO01060.1 - 1.4e-12 47.9 0.0 5.8e-12 46.0 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EOO01060.1 - 1.1e-11 45.5 0.2 3.2e-11 44.0 0.2 1.7 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Acetyltransf_3 PF13302.7 EOO01061.1 - 2e-11 44.7 0.7 2.6e-11 44.3 0.1 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EOO01061.1 - 2.6e-10 40.6 0.1 4.5e-10 39.8 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EOO01061.1 - 6e-05 23.2 0.1 7.8e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EOO01061.1 - 0.00011 22.5 0.0 0.00015 22.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EOO01061.1 - 0.0034 17.3 0.0 0.0066 16.4 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 EOO01061.1 - 0.008 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_L37e PF01907.19 EOO01061.1 - 0.0096 16.1 0.3 0.016 15.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e Amidohydro_1 PF01979.20 EOO01062.1 - 2.2e-14 53.5 0.0 2.6e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EOO01062.1 - 0.2 11.1 0.3 4.6 6.6 0.4 2.1 1 1 1 2 2 2 0 Amidohydrolase family Palm_thioest PF02089.15 EOO01063.1 - 6.1e-77 258.7 0.0 7.3e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 EOO01063.1 - 0.045 13.1 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) HTH_18 PF12833.7 EOO01063.1 - 0.12 12.7 0.0 17 5.8 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Dynamin_N PF00350.23 EOO01064.1 - 4.8e-23 82.1 0.0 1.4e-22 80.5 0.0 1.7 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EOO01064.1 - 9.7e-06 25.6 0.0 4.7e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EOO01064.1 - 1e-05 25.1 0.1 0.083 12.4 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Roc PF08477.13 EOO01064.1 - 0.00043 20.5 0.0 0.01 16.1 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 EOO01064.1 - 0.0098 15.7 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SRPRB PF09439.10 EOO01064.1 - 0.01 15.3 0.1 0.19 11.1 0.0 2.4 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EOO01064.1 - 0.014 15.2 0.0 1.7 8.4 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 EOO01064.1 - 0.075 13.5 0.0 0.096 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 EOO01064.1 - 0.086 12.4 0.0 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 Ras family Sharpin_PH PF16764.5 EOO01064.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Sharpin PH domain MMS1_N PF10433.9 EOO01065.1 - 1.8e-91 307.3 0.0 3.1e-91 306.4 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EOO01065.1 - 2e-66 224.6 0.0 1.3e-64 218.6 0.0 3.2 4 0 0 4 4 4 1 CPSF A subunit region PQQ_3 PF13570.6 EOO01065.1 - 3.1 8.4 4.5 16 6.2 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain Utp12 PF04003.12 EOO01066.1 - 0.0027 18.0 1.1 1.1 9.6 0.2 2.6 2 0 0 2 2 2 1 Dip2/Utp12 Family HAUS5 PF14817.6 EOO01066.1 - 0.0042 15.9 1.8 0.0042 15.9 1.8 2.3 2 1 1 3 3 3 1 HAUS augmin-like complex subunit 5 YscO-like PF16789.5 EOO01066.1 - 0.013 15.5 7.8 0.013 15.5 7.8 2.4 3 0 0 3 3 2 0 YscO-like protein MIP-T3_C PF17749.1 EOO01066.1 - 0.015 15.3 1.8 0.015 15.3 1.8 2.7 3 0 0 3 3 2 0 Microtubule-binding protein MIP-T3 C-terminal region CK2S PF15011.6 EOO01066.1 - 0.049 13.5 0.1 0.049 13.5 0.1 3.2 4 0 0 4 4 3 0 Casein Kinase 2 substrate Spc7 PF08317.11 EOO01066.1 - 0.051 12.5 10.2 1.2 7.9 2.7 3.2 3 0 0 3 3 3 0 Spc7 kinetochore protein UpxZ PF06603.11 EOO01066.1 - 0.064 13.6 1.4 0.14 12.4 0.4 2.1 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists Mating_N PF12731.7 EOO01066.1 - 0.089 12.9 0.7 0.23 11.6 0.7 1.8 1 0 0 1 1 1 0 Mating-type protein beta 1 RPW8 PF05659.11 EOO01066.1 - 0.19 11.4 7.6 2.5 7.8 0.5 2.7 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Cep57_CLD_2 PF14197.6 EOO01066.1 - 0.23 11.6 6.4 0.35 11.0 1.8 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 TACC_C PF05010.14 EOO01066.1 - 0.23 11.2 14.0 0.36 10.6 3.5 3.0 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal THOC7 PF05615.13 EOO01066.1 - 0.41 10.9 14.1 4.8 7.5 7.2 2.8 1 1 1 2 2 2 0 Tho complex subunit 7 MCPsignal PF00015.21 EOO01066.1 - 0.48 10.2 6.7 1.3 8.8 1.3 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF148 PF02520.17 EOO01066.1 - 0.61 10.2 5.2 1.7 8.8 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function DUF148 Sec34 PF04136.15 EOO01066.1 - 0.62 9.9 12.9 0.49 10.3 1.4 2.9 3 0 0 3 3 3 0 Sec34-like family SlyX PF04102.12 EOO01066.1 - 0.65 10.7 3.2 29 5.4 0.0 3.2 3 1 0 3 3 2 0 SlyX ApoLp-III PF07464.11 EOO01066.1 - 0.68 10.0 6.6 5.7 7.0 0.2 2.8 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Tektin PF03148.14 EOO01066.1 - 0.87 8.3 16.4 0.1 11.3 0.3 3.4 4 0 0 4 4 4 0 Tektin family YkyA PF10368.9 EOO01066.1 - 1.3 8.6 12.5 0.16 11.6 4.0 2.7 3 0 0 3 3 2 0 Putative cell-wall binding lipoprotein T3SSipB PF16535.5 EOO01066.1 - 1.5 9.3 6.6 18 5.7 0.2 3.0 3 0 0 3 3 3 0 Type III cell invasion protein SipB FliD_N PF02465.18 EOO01066.1 - 1.5 9.6 8.3 1.1 9.9 0.9 3.0 3 0 0 3 3 2 0 Flagellar hook-associated protein 2 N-terminus Syntaxin-6_N PF09177.11 EOO01066.1 - 1.5 9.4 9.4 4.8 7.8 1.0 3.2 3 0 0 3 3 2 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 EOO01066.1 - 1.7 8.8 14.2 6.3 7.0 0.2 4.1 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 EOO01066.1 - 2.3 8.7 9.6 3.5 8.2 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function DUF16 Spectrin PF00435.21 EOO01066.1 - 2.3 8.7 12.9 5.4 7.5 2.5 3.8 4 0 0 4 4 4 0 Spectrin repeat DUF1664 PF07889.12 EOO01066.1 - 2.4 8.2 9.4 6.9 6.7 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 EOO01066.1 - 2.6 6.8 8.0 1.4 7.7 5.6 1.8 2 1 0 2 2 2 0 LMBR1-like membrane protein DUF5082 PF16888.5 EOO01066.1 - 3.5 7.9 16.1 0.4 11.0 0.6 3.9 4 1 0 4 4 3 0 Domain of unknown function (DUF5082) TBCA PF02970.16 EOO01066.1 - 3.8 7.9 12.9 2.9 8.3 5.6 3.3 3 0 0 3 3 3 0 Tubulin binding cofactor A DUF948 PF06103.11 EOO01066.1 - 5.5 7.3 5.3 45 4.4 0.8 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Filament PF00038.21 EOO01066.1 - 6.5 6.2 17.4 1.3 8.5 0.2 3.5 4 0 0 4 4 4 0 Intermediate filament protein Sec8_exocyst PF04048.14 EOO01066.1 - 6.6 6.6 10.4 3.6 7.5 0.9 3.4 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF1295 PF06966.12 EOO01068.1 - 3.3e-16 59.5 0.5 4.4e-16 59.1 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 EOO01068.1 - 0.00017 20.5 5.1 0.00065 18.6 5.0 1.8 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 EOO01068.1 - 0.0002 21.4 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 EOO01068.1 - 0.0088 16.4 1.8 0.009 16.4 0.2 1.9 2 1 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 EOO01068.1 - 0.012 16.0 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family adh_short_C2 PF13561.6 EOO01069.1 - 9.6e-50 169.3 0.0 1.2e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO01069.1 - 3.1e-43 147.5 0.0 4.1e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO01069.1 - 9.2e-14 51.7 0.0 1.5e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF43 PF01861.16 EOO01069.1 - 0.0079 15.5 0.1 0.011 15.0 0.1 1.1 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_25 PF13649.6 EOO01069.1 - 0.086 13.6 0.0 0.17 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pro-kuma_activ PF09286.11 EOO01070.1 - 9.3e-28 97.3 0.0 1.6e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EOO01070.1 - 0.00047 19.5 0.0 0.00088 18.6 0.0 1.4 1 0 0 1 1 1 1 Subtilase family 2OG-FeII_Oxy PF03171.20 EOO01071.1 - 4.1e-11 43.3 0.0 6.6e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EOO01071.1 - 2.5e-06 28.2 0.0 4.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Bromodomain PF00439.25 EOO01072.1 - 4.2e-17 62.0 0.1 1.3e-16 60.4 0.0 1.9 2 0 0 2 2 2 1 Bromodomain BTB PF00651.31 EOO01072.1 - 7.7e-07 29.3 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain End_N_terminal PF12218.8 EOO01072.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Lyase_1 PF00206.20 EOO01073.1 - 3e-38 132.0 0.0 5.9e-37 127.7 0.0 2.0 1 1 1 2 2 2 2 Lyase ADSL_C PF10397.9 EOO01073.1 - 2.2e-17 63.4 0.0 4.4e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Glyoxalase PF00903.25 EOO01074.1 - 1.5e-05 25.2 0.2 6.4e-05 23.2 0.2 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Sugar_tr PF00083.24 EOO01075.1 - 5.3e-86 289.3 22.5 6.7e-86 288.9 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO01075.1 - 1.3e-17 63.8 26.4 1.9e-11 43.5 10.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3806 PF12713.7 EOO01075.1 - 0.13 12.0 0.1 0.8 9.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3806) MFS_1 PF07690.16 EOO01077.1 - 6.4e-05 22.0 3.3 0.00077 18.5 4.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 EOO01077.1 - 0.0012 17.5 0.0 0.0015 17.2 0.0 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Neurensin PF14927.6 EOO01077.1 - 0.17 11.6 2.7 0.21 11.3 0.2 2.2 1 1 1 2 2 2 0 Neurensin TP_methylase PF00590.20 EOO01078.1 - 6.7e-24 85.0 0.0 1.1e-23 84.3 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Glyco_trans_2_3 PF13632.6 EOO01079.1 - 9.6e-48 162.7 0.0 9.6e-48 162.7 0.0 2.2 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EOO01079.1 - 6.8e-06 26.0 0.0 6.3e-05 22.8 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EOO01079.1 - 0.00076 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EOO01079.1 - 0.03 13.8 0.0 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 21 UPF0016 PF01169.19 EOO01079.1 - 1.9 8.9 6.8 0.17 12.3 0.6 2.4 2 1 1 3 3 3 0 Uncharacterized protein family UPF0016 RhoGEF PF00621.20 EOO01080.1 - 8.5e-29 101.1 0.7 4.4e-26 92.2 0.0 2.4 2 0 0 2 2 2 2 RhoGEF domain ApoLp-III PF07464.11 EOO01080.1 - 0.0032 17.6 5.1 0.0032 17.6 5.1 2.9 2 2 2 4 4 4 1 Apolipophorin-III precursor (apoLp-III) DUF3507 PF12015.8 EOO01080.1 - 0.0088 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) SKA2 PF16740.5 EOO01080.1 - 0.068 13.0 9.2 0.015 15.0 2.3 2.7 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF148 PF02520.17 EOO01080.1 - 0.11 12.6 1.4 0.41 10.8 1.4 2.1 1 0 0 1 1 1 0 Domain of unknown function DUF148 Baculo_F PF12259.8 EOO01080.1 - 0.51 8.8 1.2 0.79 8.2 1.2 1.2 1 0 0 1 1 1 0 Baculovirus F protein DUF885 PF05960.11 EOO01080.1 - 0.56 9.8 5.4 3.5 7.1 3.4 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) Prominin PF05478.11 EOO01080.1 - 0.87 7.5 3.2 1.9 6.4 3.2 1.5 1 0 0 1 1 1 0 Prominin Apolipoprotein PF01442.18 EOO01080.1 - 1.3 8.8 22.2 0.65 9.9 16.9 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain ECH_2 PF16113.5 EOO01080.1 - 4.5 6.7 11.1 0.28 10.7 2.4 2.6 3 0 0 3 3 3 0 Enoyl-CoA hydratase/isomerase DUF4407 PF14362.6 EOO01080.1 - 8.6 5.6 7.9 1.6 8.0 3.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MTP18 PF10558.9 EOO01082.1 - 5e-83 277.2 0.1 6.3e-83 276.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) CAP59_mtransfer PF11735.8 EOO01083.1 - 9.3e-65 218.7 0.0 1.2e-64 218.3 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Tim54 PF11711.8 EOO01083.1 - 0.063 12.1 1.9 0.09 11.5 1.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SurE PF01975.17 EOO01084.1 - 3.9e-25 88.8 3.7 1.1e-21 77.5 1.7 2.1 1 1 1 2 2 2 2 Survival protein SurE LPAM_1 PF08139.12 EOO01084.1 - 0.081 13.5 2.1 0.081 13.5 2.1 2.8 3 0 0 3 3 3 0 Prokaryotic membrane lipoprotein lipid attachment site Sugar_tr PF00083.24 EOO01085.1 - 4.4e-40 137.9 27.7 3.3e-31 108.7 9.2 2.7 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO01085.1 - 1.7e-08 33.8 32.7 1.6e-06 27.3 8.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily SHR3_chaperone PF08229.11 EOO01085.1 - 0.085 11.8 2.2 0.47 9.4 0.2 2.2 2 0 0 2 2 2 0 ER membrane protein SH3 DUF1072 PF06380.11 EOO01085.1 - 0.16 11.8 3.0 0.19 11.7 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) p450 PF00067.22 EOO01086.1 - 3.7e-70 237.0 0.0 5.6e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 EOO01086.1 - 1.2e-27 97.0 0.0 2.5e-27 95.9 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 EOO01086.1 - 2.4e-25 89.4 0.0 6.1e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EOO01086.1 - 3e-11 43.9 0.0 9.1e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EOO01086.1 - 0.007 16.6 0.0 0.025 14.8 0.0 2.0 1 0 0 1 1 1 1 Flavodoxin domain ABC_tran PF00005.27 EOO01087.1 - 7e-29 101.1 0.1 7.7e-25 88.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EOO01087.1 - 6.3e-08 32.3 0.0 7.3e-06 25.6 0.0 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EOO01087.1 - 5.1e-07 29.8 0.1 0.013 15.4 0.1 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane PF00664.23 EOO01087.1 - 7e-07 29.2 11.2 0.0008 19.1 0.0 3.1 2 1 1 3 3 3 2 ABC transporter transmembrane region AAA_22 PF13401.6 EOO01087.1 - 0.017 15.4 0.6 0.15 12.4 0.6 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EOO01087.1 - 0.034 13.9 0.8 0.085 12.6 0.8 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 EOO01087.1 - 0.048 13.4 0.0 0.32 10.6 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 EOO01087.1 - 0.082 13.0 0.1 0.17 12.0 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 EOO01087.1 - 0.14 12.5 0.1 2.5 8.4 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 EOO01087.1 - 0.14 12.2 0.9 0.46 10.5 0.5 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain SUR7 PF06687.12 EOO01087.1 - 0.16 11.6 0.0 0.16 11.6 0.0 2.5 2 2 0 2 2 2 0 SUR7/PalI family Peptidase_C13 PF01650.18 EOO01088.1 - 1.1e-40 139.7 0.3 1.5e-40 139.3 0.3 1.1 1 0 0 1 1 1 1 Peptidase C13 family Sugar_tr PF00083.24 EOO01089.1 - 3.3e-64 217.4 13.5 1.2e-62 212.3 9.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO01089.1 - 7.7e-18 64.5 19.0 2.1e-12 46.7 11.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Ferric_reduct PF01794.19 EOO01089.1 - 0.019 15.1 3.8 0.051 13.7 3.8 1.7 1 0 0 1 1 1 0 Ferric reductase like transmembrane component Methyltransf_23 PF13489.6 EOO01090.1 - 8.3e-06 25.7 0.0 0.0013 18.6 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain AA_permease PF00324.21 EOO01091.1 - 4.4e-96 322.4 36.0 5.3e-96 322.1 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EOO01091.1 - 1.5e-19 70.2 38.4 1.8e-19 69.9 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease BTB PF00651.31 EOO01092.1 - 7.1e-06 26.2 0.0 0.0001 22.5 0.0 2.6 3 0 0 3 3 3 1 BTB/POZ domain CDC45 PF02724.14 EOO01092.1 - 0.21 9.9 2.4 0.23 9.7 2.4 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EOO01092.1 - 0.23 10.8 6.0 0.3 10.5 6.0 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EOO01092.1 - 1.5 6.8 12.6 2.2 6.3 12.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 EOO01092.1 - 6.3 6.0 12.8 9.9 5.4 12.8 1.2 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 EOO01092.1 - 6.5 6.4 14.2 15 5.2 14.2 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Med4 PF10018.9 EOO01093.1 - 1.2e-42 145.9 4.2 2.2e-42 144.9 4.1 1.5 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Dynamin_N PF00350.23 EOO01093.1 - 0.057 13.5 1.2 4 7.5 0.1 2.3 2 0 0 2 2 2 0 Dynamin family DUF4407 PF14362.6 EOO01093.1 - 0.23 10.8 10.8 0.57 9.5 3.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 EOO01093.1 - 0.37 10.3 4.5 2.7 7.5 0.3 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Presenilin PF01080.17 EOO01093.1 - 1 8.1 2.0 1.4 7.6 2.0 1.2 1 0 0 1 1 1 0 Presenilin AAA_11 PF13086.6 EOO01093.1 - 5.6 6.7 9.5 0.77 9.5 2.7 2.0 2 0 0 2 2 2 0 AAA domain Glyco_hydro_3_C PF01915.22 EOO01094.1 - 1.4e-44 152.5 0.0 3.1e-44 151.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Cyclin_N PF00134.23 EOO01094.1 - 9.4e-09 35.1 0.1 1.7e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Glyco_hydro_3 PF00933.21 EOO01094.1 - 3.9e-08 33.0 0.0 6.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Sld5 PF05916.11 EOO01095.1 - 9e-30 103.3 0.0 1.4e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Ribosomal_60s PF00428.19 EOO01095.1 - 3 8.5 8.1 0.81 10.3 4.3 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Rad4 PF03835.15 EOO01096.1 - 1.7e-36 125.1 2.2 1.1e-35 122.4 2.2 2.5 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EOO01096.1 - 1.4e-26 92.7 1.4 5e-26 90.9 0.7 2.2 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EOO01096.1 - 1.4e-20 72.8 0.3 3.3e-20 71.6 0.3 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EOO01096.1 - 1.6e-14 54.6 0.3 1.6e-14 54.6 0.3 5.5 6 1 1 7 7 7 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EOO01096.1 - 0.023 15.2 0.0 0.089 13.3 0.0 2.1 1 0 0 1 1 1 0 Transglutaminase-like superfamily EF-hand_7 PF13499.6 EOO01097.1 - 4.1e-14 52.8 0.3 5.4e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EOO01097.1 - 1.7e-12 47.5 0.1 5.2e-06 26.7 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 EOO01097.1 - 2.5e-11 42.6 0.7 9.6e-05 22.0 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EOO01097.1 - 1.1e-10 40.2 0.3 0.00055 19.3 0.0 3.8 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EOO01097.1 - 5.7e-08 32.5 0.3 7.6e-05 22.5 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain pair MTP18 PF10558.9 EOO01098.1 - 0.74 9.7 3.6 1.5 8.7 3.6 1.6 1 1 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) R3H-assoc PF13902.6 EOO01099.1 - 2.5e-20 73.2 1.1 5.2e-20 72.2 0.9 1.6 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 EOO01099.1 - 0.014 15.4 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 R3H domain SH3_1 PF00018.28 EOO01101.1 - 8e-28 95.8 0.0 1.6e-13 50.0 0.0 2.9 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 EOO01101.1 - 5.1e-19 67.9 0.2 1.8e-09 37.3 0.1 3.1 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.24 EOO01101.1 - 1.2e-14 54.3 0.0 2.4e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 EOO01101.1 - 3.3e-12 45.9 0.0 9.2e-08 31.7 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain PB1 PF00564.24 EOO01101.1 - 2.2e-08 33.9 0.0 3.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Rad60-SLD PF11976.8 EOO01101.1 - 0.00057 19.7 0.1 0.0029 17.4 0.1 2.1 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EOO01101.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family Methyltransf_11 PF08241.12 EOO01102.1 - 9.2e-20 71.1 0.0 1.4e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO01102.1 - 1e-17 64.6 0.0 1.5e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO01102.1 - 4.4e-10 40.2 0.0 7.6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO01102.1 - 1.7e-07 31.1 0.0 2.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EOO01102.1 - 2.7e-07 30.5 0.0 4.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EOO01102.1 - 0.0001 21.7 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EOO01102.1 - 0.00083 19.0 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 EOO01102.1 - 0.0031 16.7 0.0 0.0046 16.1 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.20 EOO01102.1 - 0.0033 16.5 0.0 0.0047 16.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.7 EOO01102.1 - 0.014 15.3 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 EOO01102.1 - 0.021 14.5 0.0 0.028 14.0 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) CMAS PF02353.20 EOO01102.1 - 0.057 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 EOO01102.1 - 0.16 11.9 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_cc PF11790.8 EOO01103.1 - 3.9e-61 206.7 0.0 4.4e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Tyosinase_C PF18132.1 EOO01105.1 - 1.5e-26 93.4 0.8 1.2e-25 90.6 0.0 2.5 2 1 1 3 3 3 1 Tyosinase C-terminal domain Tyrosinase PF00264.20 EOO01105.1 - 5.4e-23 82.5 7.0 8.4e-23 81.8 7.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF4407 PF14362.6 EOO01106.1 - 0.11 11.8 0.1 0.11 11.8 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Sugar_tr PF00083.24 EOO01107.1 - 5.9e-23 81.4 6.7 9.5e-18 64.3 1.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO01107.1 - 3.7e-18 65.6 2.9 6.1e-18 64.9 2.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EOO01107.1 - 0.00011 20.9 0.6 0.00011 20.9 0.6 1.4 2 0 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.13 EOO01107.1 - 0.0024 16.4 0.5 0.0029 16.1 0.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EOO01107.1 - 0.0029 16.5 0.3 0.0029 16.5 0.3 1.4 2 0 0 2 2 2 1 MFS_1 like family LacY_symp PF01306.19 EOO01107.1 - 0.015 14.1 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 LacY proton/sugar symporter Ion_trans PF00520.31 EOO01108.1 - 1.6e-10 40.7 19.7 4.8e-10 39.1 19.7 1.8 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EOO01108.1 - 1.5e-05 23.8 9.9 0.0067 15.2 0.4 2.2 1 1 1 2 2 2 2 Polycystin cation channel PNTB_4TM PF12769.7 EOO01108.1 - 0.0049 17.3 0.2 0.0049 17.3 0.2 1.9 2 0 0 2 2 2 1 4TM region of pyridine nucleotide transhydrogenase, mitoch FMO-like PF00743.19 EOO01109.1 - 4.3e-16 58.4 0.2 4e-13 48.6 0.1 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EOO01109.1 - 2.1e-12 46.9 1.0 3.8e-11 42.8 0.5 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EOO01109.1 - 3.1e-10 40.1 0.0 9.5e-10 38.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EOO01109.1 - 5.9e-10 38.9 0.0 1.8e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EOO01109.1 - 1.2e-06 27.9 1.3 0.00057 19.1 0.1 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EOO01109.1 - 6.2e-05 22.7 0.0 0.0065 16.1 0.0 3.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EOO01109.1 - 0.00045 19.5 0.1 0.0018 17.5 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 EOO01109.1 - 0.0014 18.6 0.0 0.049 13.6 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EOO01109.1 - 0.035 13.2 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EOO01109.1 - 0.088 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Glyco_trans_1_4 PF13692.6 EOO01110.1 - 1.9e-08 34.8 0.0 3.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EOO01110.1 - 0.00012 22.4 0.0 0.00023 21.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Fungal_trans PF04082.18 EOO01111.1 - 0.00095 18.3 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ProRS-C_1 PF09180.11 EOO01112.1 - 2.3e-23 82.2 0.2 4.5e-23 81.3 0.2 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EOO01112.1 - 1.5e-21 77.2 0.0 3.7e-21 75.9 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EOO01112.1 - 1e-16 60.8 0.0 2.7e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain DnaB_2 PF07261.11 EOO01112.1 - 0.023 14.5 1.1 0.067 12.9 1.1 1.7 1 0 0 1 1 1 0 Replication initiation and membrane attachment SGL PF08450.12 EOO01113.1 - 8.1e-27 94.4 0.0 9.5e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EOO01113.1 - 1.3e-05 25.2 0.0 0.015 15.4 0.0 2.4 2 0 0 2 2 2 2 Strictosidine synthase Arylesterase PF01731.20 EOO01113.1 - 0.021 15.0 0.0 4.3 7.6 0.0 2.7 2 1 0 2 2 2 0 Arylesterase CAP PF00188.26 EOO01114.1 - 1.6e-16 61.3 3.1 2.2e-16 60.8 3.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family zf-AN1 PF01428.16 EOO01115.1 - 4.7e-25 87.5 25.3 2e-12 47.1 10.3 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 EOO01115.1 - 0.0043 17.3 4.3 0.0043 17.3 4.3 2.7 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 EOO01115.1 - 0.054 13.8 15.9 0.33 11.3 5.3 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Remorin_C PF03763.13 EOO01115.1 - 0.51 10.2 4.5 0.13 12.2 1.3 1.6 2 0 0 2 2 2 0 Remorin, C-terminal region DpnI PF06044.12 EOO01115.1 - 2.2 7.9 5.5 4.2 7.0 0.8 2.3 2 0 0 2 2 2 0 Dam-replacing family Ank_2 PF12796.7 EOO01116.1 - 9.2e-36 122.3 5.1 0.00044 20.8 0.0 13.4 13 1 2 15 15 15 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EOO01116.1 - 2.1e-19 69.6 12.5 0.1 13.2 0.0 13.9 15 2 2 17 17 17 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EOO01116.1 - 2.2e-13 50.1 2.7 2e-05 24.8 0.0 8.9 10 1 1 11 11 11 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EOO01116.1 - 1.5e-12 46.5 10.3 6 7.8 0.0 15.9 21 0 0 21 21 21 2 Ankyrin repeat Ank PF00023.30 EOO01116.1 - 6.5e-08 32.7 13.7 0.58 10.7 0.0 11.4 12 0 0 12 12 12 2 Ankyrin repeat BIR PF00653.21 EOO01117.1 - 5.3e-21 75.1 0.1 1.1e-20 74.1 0.1 1.5 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain adh_short PF00106.25 EOO01118.1 - 1.1e-10 41.3 0.0 1.5e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO01118.1 - 1.8e-08 34.3 0.1 2.2e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EOO01118.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 EOO01118.1 - 0.0017 18.9 0.0 0.0032 18.0 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EOO01118.1 - 0.0075 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 EOO01118.1 - 0.014 14.8 0.0 0.028 13.9 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EOO01118.1 - 0.023 14.6 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EOO01118.1 - 0.024 14.7 0.0 0.037 14.1 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 EOO01118.1 - 0.044 13.3 0.5 0.089 12.3 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family ApbA PF02558.16 EOO01118.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Transp_cyt_pur PF02133.15 EOO01119.1 - 1.4e-26 93.3 32.2 3.2e-26 92.1 32.2 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin EAP30 PF04157.16 EOO01120.1 - 4e-44 150.7 0.0 5.2e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 EOO01120.1 - 3.4e-23 81.6 0.0 5.8e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 EOO01120.1 - 0.0036 17.2 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Pyr_redox_3 PF13738.6 EOO01121.1 - 1.6e-10 40.7 0.0 2.6e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EOO01121.1 - 9.8e-10 37.5 0.0 1.4e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EOO01121.1 - 1.5e-07 30.9 0.0 3.5e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EOO01121.1 - 1.2e-05 24.7 0.0 0.00023 20.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EOO01121.1 - 0.066 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase QCR10 PF09796.9 EOO01122.1 - 4.5e-28 97.1 0.5 5.5e-28 96.8 0.5 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) SET PF00856.28 EOO01123.1 - 1e-16 61.8 0.2 1.2e-15 58.3 0.0 2.6 2 1 0 2 2 2 1 SET domain TPR_2 PF07719.17 EOO01123.1 - 3.2e-08 33.1 1.4 0.0036 17.3 0.9 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EOO01123.1 - 0.00039 20.1 2.4 0.071 13.0 0.6 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EOO01123.1 - 0.0004 19.9 0.1 0.00067 19.1 0.1 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_12 PF13424.6 EOO01123.1 - 0.001 19.3 3.0 0.0021 18.3 1.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EOO01123.1 - 0.0026 17.8 2.3 0.0066 16.6 0.3 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EOO01123.1 - 0.0039 17.9 1.1 0.032 15.0 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EOO01123.1 - 0.017 15.6 6.3 0.62 10.6 1.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EOO01123.1 - 0.43 11.3 1.7 3.7 8.4 0.6 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SNO PF01174.19 EOO01124.1 - 7.6e-54 182.4 0.0 2.6e-43 148.1 0.0 2.0 1 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EOO01124.1 - 2.1e-08 34.0 0.0 1.4e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 EOO01124.1 - 0.028 14.2 0.0 0.16 11.7 0.0 1.9 1 1 0 1 1 1 0 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 EOO01124.1 - 0.039 13.6 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 CoA_binding_2 PF13380.6 EOO01125.1 - 1.6e-28 99.5 0.1 2.1e-28 99.1 0.1 1.1 1 0 0 1 1 1 1 CoA binding domain adh_short PF00106.25 EOO01126.1 - 4.1e-39 134.1 0.1 6.1e-39 133.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO01126.1 - 1.7e-28 99.8 0.0 2.5e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EOO01126.1 - 0.02 14.3 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 EOO01127.1 - 1.5e-07 31.5 0.1 2.5e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EOO01127.1 - 1.4e-06 28.1 0.0 5.9e-06 26.1 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EOO01127.1 - 0.026 14.0 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase RRN3 PF05327.11 EOO01128.1 - 0.032 12.8 7.2 0.038 12.5 7.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 EOO01128.1 - 0.045 13.4 3.9 0.061 13.0 3.9 1.2 1 0 0 1 1 1 0 FAM176 family Cytomega_UL84 PF06284.11 EOO01128.1 - 0.38 9.1 1.5 0.38 9.2 1.5 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein BUD22 PF09073.10 EOO01128.1 - 0.52 9.6 6.0 0.59 9.4 6.0 1.0 1 0 0 1 1 1 0 BUD22 Mak16 PF04874.14 EOO01128.1 - 0.52 10.9 14.2 0.72 10.5 14.2 1.1 1 0 0 1 1 1 0 Mak16 protein C-terminal region Med17 PF10156.9 EOO01128.1 - 1 8.0 4.7 1.2 7.7 4.7 1.0 1 0 0 1 1 1 0 Subunit 17 of Mediator complex TRAP_alpha PF03896.16 EOO01128.1 - 1.1 8.4 6.1 1.4 8.1 6.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pox_Ag35 PF03286.14 EOO01128.1 - 1.3 8.8 11.3 1.8 8.4 11.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GCIP PF13324.6 EOO01128.1 - 1.6 8.3 7.8 1.8 8.1 7.8 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 EOO01128.1 - 4 5.4 20.7 5.1 5.1 20.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi PI3K_1B_p101 PF10486.9 EOO01128.1 - 5.1 4.7 10.3 6.2 4.5 10.3 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF1996 PF09362.10 EOO01129.1 - 9.6e-55 186.1 1.4 1.2e-54 185.9 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Pkinase PF00069.25 EOO01130.1 - 2.3e-34 119.0 0.0 2.6e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO01130.1 - 5.5e-16 58.6 0.0 6.9e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EOO01130.1 - 0.038 13.3 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Transketolase_N PF00456.21 EOO01131.1 - 1.6e-106 356.1 0.0 2.2e-106 355.6 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EOO01131.1 - 6e-33 114.0 0.1 1.9e-32 112.4 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EOO01131.1 - 6.3e-11 42.2 0.0 1.3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EOO01131.1 - 7.6e-07 28.6 0.0 8.7e-06 25.1 0.0 2.4 2 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EOO01131.1 - 0.00065 19.5 2.6 0.00092 19.0 0.3 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 EOO01131.1 - 0.011 14.7 0.1 0.023 13.6 0.1 1.5 1 0 0 1 1 1 0 Dehydrogenase E1 component TPP_enzyme_N PF02776.18 EOO01131.1 - 0.023 14.3 0.1 5.1 6.7 0.1 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Scm3 PF10384.9 EOO01131.1 - 0.11 12.2 0.5 0.26 11.1 0.5 1.6 1 0 0 1 1 1 0 Centromere protein Scm3 Med3 PF11593.8 EOO01132.1 - 1.1 8.4 9.2 1.4 8.0 9.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GSDH PF07995.11 EOO01133.1 - 1.3e-118 396.1 0.1 1.6e-118 395.9 0.1 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Reg_prop PF07494.11 EOO01133.1 - 0.0035 17.4 2.8 4.3 7.9 0.0 4.1 4 0 0 4 4 4 2 Two component regulator propeller NHL PF01436.21 EOO01133.1 - 0.0079 16.2 0.0 0.063 13.4 0.0 2.6 3 0 0 3 3 3 1 NHL repeat MIP PF00230.20 EOO01134.1 - 3.9e-47 160.8 13.5 5.1e-47 160.5 13.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein Epimerase PF01370.21 EOO01135.1 - 1.3e-44 152.5 0.0 1.8e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO01135.1 - 1.2e-42 146.5 0.0 2.1e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EOO01135.1 - 9.5e-14 51.1 0.0 4.7e-13 48.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EOO01135.1 - 5.5e-10 38.8 0.0 7.5e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EOO01135.1 - 1e-09 38.0 0.0 6.6e-08 32.0 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EOO01135.1 - 1.6e-06 27.7 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO01135.1 - 0.00019 21.1 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.14 EOO01135.1 - 0.00098 18.7 0.1 0.0017 17.9 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_4 PF07993.12 EOO01135.1 - 0.0011 18.2 0.0 0.0033 16.6 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EOO01135.1 - 0.0042 17.0 0.0 0.0068 16.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3HCDH_N PF02737.18 EOO01135.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SNF2_N PF00176.23 EOO01137.1 - 2.5e-32 112.0 0.5 4.6e-28 97.9 0.0 2.4 1 1 1 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.15 EOO01137.1 - 6.7e-06 26.2 0.4 4.4e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 EOO01137.1 - 1.6e-05 24.0 0.0 3.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-C3HC4 PF00097.25 EOO01137.1 - 2.5e-05 24.1 11.9 5.2e-05 23.0 11.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 EOO01137.1 - 0.00017 21.9 0.0 0.0005 20.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.6 EOO01137.1 - 0.00029 20.9 10.5 0.00072 19.7 10.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DEAD PF00270.29 EOO01137.1 - 0.00052 19.8 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.6 EOO01137.1 - 0.00057 19.9 11.7 0.0012 18.8 11.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EOO01137.1 - 0.01 15.6 11.7 0.022 14.6 11.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EOO01137.1 - 0.055 13.3 11.6 0.1 12.5 11.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EOO01137.1 - 0.065 13.1 10.0 0.14 12.0 10.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EOO01137.1 - 0.24 11.4 11.4 0.62 10.1 11.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EOO01137.1 - 0.89 9.9 12.6 2 8.8 12.6 1.5 1 0 0 1 1 1 0 Ring finger domain DHO_dh PF01180.21 EOO01138.1 - 7.7e-65 219.0 0.0 1e-62 212.0 0.0 2.0 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EOO01138.1 - 3.9e-05 22.8 0.6 0.00037 19.6 0.3 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase PcrB PF01884.17 EOO01138.1 - 0.0036 16.8 0.4 2.4 7.5 0.0 2.4 2 0 0 2 2 2 2 PcrB family OCD_Mu_crystall PF02423.15 EOO01139.1 - 2e-13 49.9 0.0 2.4e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EOO01139.1 - 1.1e-06 28.7 0.0 8.7e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TruB_C PF09142.11 EOO01139.1 - 0.024 14.4 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Sacchrp_dh_NADP PF03435.18 EOO01139.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain EMP70 PF02990.16 EOO01140.1 - 3.7e-209 695.7 4.2 5.2e-209 695.2 4.2 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 NUC153 PF08159.12 EOO01141.1 - 6.7e-15 54.6 0.3 6.7e-15 54.6 0.3 3.6 3 0 0 3 3 3 2 NUC153 domain DEC-1_C PF04626.13 EOO01141.1 - 0.32 11.4 0.1 0.32 11.4 0.1 2.6 3 0 0 3 3 3 0 Dec-1 protein, C terminal region Aldedh PF00171.22 EOO01142.1 - 4.5e-77 259.5 1.2 1.1e-40 139.6 0.3 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 EOO01142.1 - 0.039 13.4 0.2 0.82 9.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1487) Adenine_glyco PF03352.13 EOO01142.1 - 0.04 13.7 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyladenine glycosylase LuxC PF05893.14 EOO01142.1 - 0.089 11.8 0.2 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Ad_Cy_reg PF16701.5 EOO01142.1 - 0.093 12.5 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase regulatory domain DUF2781 PF10914.8 EOO01143.1 - 2.3e-31 109.2 4.6 2.6e-31 109.0 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) adh_short PF00106.25 EOO01144.1 - 1.7e-38 132.0 0.0 2.3e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO01144.1 - 3.1e-24 85.8 0.1 4.3e-24 85.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO01144.1 - 2.5e-07 30.8 0.3 6.4e-07 29.4 0.3 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO01144.1 - 1.3e-06 28.1 0.1 2.3e-06 27.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EOO01144.1 - 2e-05 24.1 0.0 2.7e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EOO01144.1 - 0.00019 21.4 0.4 0.00041 20.3 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H-binding PLDc_2 PF13091.6 EOO01145.1 - 3.3e-20 72.3 0.1 1.2e-10 41.4 0.0 3.1 2 1 0 2 2 2 2 PLD-like domain Regulator_TrmB PF11495.8 EOO01145.1 - 0.00019 20.7 0.0 0.012 14.8 0.0 2.3 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB PLDc PF00614.22 EOO01145.1 - 0.00028 20.9 0.9 1.1 9.6 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Cellulase PF00150.18 EOO01146.1 - 2.8e-23 82.7 0.3 3.7e-23 82.3 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EOO01146.1 - 6.8e-07 28.7 0.0 1.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4038 PF13204.6 EOO01146.1 - 0.0006 19.5 0.2 0.0011 18.7 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 EOO01146.1 - 0.0023 17.3 0.5 0.0082 15.5 0.1 1.9 2 0 0 2 2 2 1 Beta-galactosidase Peptidase_S8 PF00082.22 EOO01147.1 - 1.5e-53 182.0 0.0 2.4e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EOO01147.1 - 1.2e-11 45.3 0.3 2.2e-11 44.4 0.3 1.4 1 0 0 1 1 1 1 Fn3-like domain Tam41_Mmp37 PF09139.11 EOO01148.1 - 1e-128 429.4 0.0 1.1e-128 429.2 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Sugar_tr PF00083.24 EOO01149.1 - 8.2e-85 285.3 21.7 2.2e-68 231.2 4.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO01149.1 - 1e-19 70.7 23.6 1.7e-19 70.0 23.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EOO01149.1 - 9.5e-05 21.0 1.0 0.00019 20.0 1.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HrpB1_HrpK PF09613.10 EOO01149.1 - 0.0064 16.1 0.4 0.018 14.7 0.1 1.8 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) Phage_holin_3_2 PF04550.12 EOO01149.1 - 0.01 16.3 3.9 0.021 15.4 2.0 2.5 2 1 1 3 3 3 0 Phage holin family 2 zf-RNPHF PF08080.12 EOO01149.1 - 0.15 12.0 0.1 27 4.8 0.0 2.4 2 0 0 2 2 2 0 RNPHF zinc finger ADH_zinc_N PF00107.26 EOO01151.1 - 1.3e-23 83.4 0.1 3.1e-23 82.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EOO01151.1 - 1.8e-18 67.9 0.0 3.6e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EOO01151.1 - 1.7e-09 37.5 0.0 4.1e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EOO01151.1 - 0.00016 21.6 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 EOO01151.1 - 0.014 14.9 0.3 0.029 13.8 0.3 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Caps_synth PF05704.12 EOO01151.1 - 0.019 14.4 0.0 0.044 13.2 0.0 1.5 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein Methyltransf_19 PF04672.12 EOO01151.1 - 0.2 11.1 0.7 6.7 6.1 0.2 2.3 2 0 0 2 2 2 0 S-adenosyl methyltransferase muHD PF10291.9 EOO01152.1 - 3.7e-70 236.4 0.0 5.6e-70 235.8 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 EOO01152.1 - 5e-07 29.9 0.3 2e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF922 PF06037.11 EOO01152.1 - 0.0072 16.1 2.5 0.54 10.0 0.6 2.3 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF922) UPF0227 PF05728.12 EOO01152.1 - 0.0098 15.8 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Laminin_II PF06009.12 EOO01152.1 - 0.041 13.9 1.5 0.11 12.6 1.5 1.8 1 1 0 1 1 1 0 Laminin Domain II DUF3340 PF11818.8 EOO01152.1 - 0.13 12.5 2.4 0.31 11.2 2.4 1.6 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) SIR2 PF02146.17 EOO01152.1 - 0.25 11.3 1.4 0.42 10.5 1.4 1.3 1 0 0 1 1 1 0 Sir2 family V_ATPase_I PF01496.19 EOO01152.1 - 0.88 7.4 4.2 1.2 6.9 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mpv17_PMP22 PF04117.12 EOO01153.1 - 2.1e-16 59.9 0.8 2.1e-16 59.9 0.8 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family DIE2_ALG10 PF04922.12 EOO01154.1 - 7.9e-22 78.1 0.3 1.2e-21 77.5 0.3 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family TRAM1 PF08390.11 EOO01154.1 - 0.45 10.2 2.1 1.3 8.8 2.1 1.8 1 0 0 1 1 1 0 TRAM1-like protein F-box-like PF12937.7 EOO01156.1 - 0.018 14.9 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 F-box-like DUF1610 PF07754.11 EOO01156.1 - 0.061 13.3 0.5 0.14 12.2 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) TFIIIC_delta PF12657.7 EOO01157.1 - 2.9e-19 69.7 0.0 2.5e-17 63.4 0.0 2.7 1 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 EOO01157.1 - 4.4e-12 45.8 3.4 9.3e-12 44.8 3.4 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex ACOX PF01756.19 EOO01158.1 - 2e-47 161.1 0.2 5.7e-47 159.6 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EOO01158.1 - 8.9e-30 103.8 0.4 2.7e-29 102.3 0.4 1.9 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EOO01158.1 - 4.5e-11 42.8 0.0 8.5e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EOO01158.1 - 4.3e-05 23.8 0.4 0.002 18.4 0.4 2.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EOO01158.1 - 0.028 15.1 0.0 0.076 13.7 0.0 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Raf1_N PF18578.1 EOO01158.1 - 0.097 13.2 0.2 0.57 10.7 0.1 2.2 2 0 0 2 2 2 0 Rubisco accumulation factor 1 alpha helical domain GATase_6 PF13522.6 EOO01159.1 - 6.1e-15 55.6 0.0 1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EOO01159.1 - 4e-12 46.1 0.0 8.4e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EOO01159.1 - 6.8e-05 21.9 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Serglycin PF04360.12 EOO01160.1 - 0.0045 16.9 10.1 0.0045 16.9 10.1 1.8 1 1 1 2 2 2 1 Serglycin Carb_anhydrase PF00194.21 EOO01161.1 - 9.8e-10 38.4 0.5 5.7e-07 29.3 0.1 2.3 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Inhibitor_I36 PF03995.13 EOO01162.1 - 1.5e-05 24.8 0.4 6.3e-05 22.8 0.2 2.1 2 1 1 3 3 3 1 Peptidase inhibitor family I36 DUF2188 PF09954.9 EOO01162.1 - 0.17 12.1 0.8 0.28 11.3 0.3 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) DUF4419 PF14388.6 EOO01163.1 - 2.7e-75 253.6 0.0 3.3e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) PTR2 PF00854.21 EOO01165.1 - 5.9e-34 117.6 5.3 7.8e-34 117.2 5.3 1.2 1 0 0 1 1 1 1 POT family DUF5316 PF17247.2 EOO01165.1 - 0.051 13.6 1.3 1 9.4 0.4 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5316) Dynamin_N PF00350.23 EOO01166.1 - 6.4e-05 23.1 1.8 0.0003 20.9 0.0 2.5 3 0 0 3 3 3 1 Dynamin family Syntaxin-6_N PF09177.11 EOO01166.1 - 0.11 13.0 0.4 0.4 11.3 0.2 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Aldo_ket_red PF00248.21 EOO01167.1 - 1.6e-16 60.4 0.0 1.7e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TetR_C_16 PF17920.1 EOO01168.1 - 0.024 14.9 3.7 0.73 10.1 1.4 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ALF PF03752.13 EOO01168.1 - 0.098 12.6 1.5 0.1 12.6 0.7 1.4 1 1 0 1 1 1 0 Short repeats of unknown function FAD_binding_4 PF01565.23 EOO01169.1 - 8.5e-23 80.6 1.1 1.7e-22 79.7 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EOO01169.1 - 3.1e-12 46.4 0.1 8.6e-12 45.0 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like PAPS_reduct PF01507.19 EOO01170.1 - 1.1e-27 97.2 0.0 6.8e-25 88.1 0.0 2.1 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ODV-E18 PF10717.9 EOO01170.1 - 0.2 11.6 0.0 0.46 10.4 0.0 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Mito_carr PF00153.27 EOO01171.1 - 4.6e-56 186.7 5.1 6.4e-19 67.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_zinc_N PF00107.26 EOO01172.1 - 3.7e-10 39.9 0.0 1.5e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EOO01172.1 - 4.2e-10 39.5 0.0 1e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EOO01172.1 - 0.00021 20.8 0.2 0.00033 20.2 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Acylphosphatase PF00708.18 EOO01172.1 - 0.087 13.2 0.0 0.4 11.1 0.0 2.0 2 0 0 2 2 2 0 Acylphosphatase Glyco_hydro_16 PF00722.21 EOO01173.1 - 2.1e-10 40.4 0.5 3.5e-10 39.6 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 UQ_con PF00179.26 EOO01174.1 - 3.6e-36 123.9 0.0 4.3e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Amidohydro_2 PF04909.14 EOO01175.1 - 2e-30 106.6 0.1 2.3e-30 106.4 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase SAVED PF18145.1 EOO01175.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain DEAD PF00270.29 EOO01176.1 - 5.6e-46 156.5 0.0 1.1e-45 155.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 EOO01176.1 - 1e-22 80.1 0.0 4.2e-22 78.1 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 EOO01176.1 - 2.6e-22 79.2 0.1 1.7e-21 76.6 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO01176.1 - 7.1e-08 32.6 0.7 4.7e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 EOO01176.1 - 0.022 14.9 0.0 0.069 13.3 0.0 1.8 1 0 0 1 1 1 0 Helicase C-terminal domain YodL PF14191.6 EOO01177.1 - 0.061 14.2 0.1 22 6.0 0.0 2.5 2 1 0 2 2 2 0 YodL-like TetR_C_33 PF13305.6 EOO01177.1 - 0.16 12.8 0.0 0.31 11.8 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain adh_short PF00106.25 EOO01178.1 - 1.1e-10 41.2 0.3 4.7e-09 36.0 0.4 2.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EOO01178.1 - 1.5e-08 34.5 0.8 1.5e-07 31.3 1.0 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO01178.1 - 0.0019 18.2 0.1 0.0023 17.9 0.1 1.1 1 0 0 1 1 1 1 KR domain Bac_luciferase PF00296.20 EOO01180.1 - 2.2e-62 211.3 0.2 3.3e-62 210.7 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Peptidase_S8 PF00082.22 EOO01181.1 - 1.6e-30 106.4 1.5 1.1e-15 57.7 0.2 2.3 1 1 1 2 2 2 2 Subtilase family fn3_5 PF06280.12 EOO01181.1 - 1.8e-11 44.8 0.0 3.4e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain SGL PF08450.12 EOO01183.1 - 3.2e-20 72.8 0.0 5.6e-20 72.0 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 EOO01183.1 - 6e-05 22.9 0.5 0.21 11.7 0.1 3.0 2 0 0 2 2 2 2 NHL repeat Str_synth PF03088.16 EOO01183.1 - 0.0016 18.6 0.0 0.0041 17.2 0.0 1.7 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 EOO01183.1 - 0.016 15.4 0.0 0.08 13.1 0.0 2.1 2 0 0 2 2 2 0 Arylesterase adh_short PF00106.25 EOO01184.1 - 4.5e-35 120.9 0.0 5e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO01184.1 - 9.4e-22 77.7 0.0 1.1e-21 77.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO01184.1 - 1.7e-05 24.8 0.0 5.2e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EOO01184.1 - 0.0028 16.7 0.0 0.0065 15.5 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EOO01184.1 - 0.018 14.5 0.0 0.022 14.2 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DJ-1_PfpI PF01965.24 EOO01186.1 - 1.3e-16 60.9 0.0 5e-16 58.9 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EOO01186.1 - 5.6e-12 45.8 0.0 1.3e-10 41.3 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 EOO01186.1 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain HIF-1a_CTAD PF08778.10 EOO01186.1 - 0.089 12.4 0.8 0.35 10.5 0.0 2.3 3 0 0 3 3 3 0 HIF-1 alpha C terminal transactivation domain Sad1_UNC PF07738.13 EOO01187.1 - 1.4e-06 28.4 0.0 7.5e-05 22.8 0.0 2.5 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal XhlA PF10779.9 EOO01187.1 - 1.8 8.9 4.3 3.3 8.0 1.0 3.1 3 0 0 3 3 3 0 Haemolysin XhlA Methyltransf_31 PF13847.6 EOO01188.1 - 2.2e-26 92.5 0.0 2.9e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO01188.1 - 6e-21 74.9 0.0 1.8e-20 73.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO01188.1 - 6.5e-21 74.8 0.0 3.3e-20 72.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EOO01188.1 - 1.1e-16 60.9 0.0 1.6e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EOO01188.1 - 5.8e-12 46.2 0.0 8.6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EOO01188.1 - 2.2e-08 34.1 0.0 3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EOO01188.1 - 2.7e-07 30.3 0.0 4.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EOO01188.1 - 8.4e-07 28.6 0.0 2.7e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_32 PF13679.6 EOO01188.1 - 5.7e-06 26.4 0.0 8.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EOO01188.1 - 5.1e-05 22.9 0.0 8.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 EOO01188.1 - 9.4e-05 22.3 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 EOO01188.1 - 0.0024 17.7 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 EOO01188.1 - 0.0024 17.2 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_9 PF08003.11 EOO01188.1 - 0.0029 16.6 0.0 0.0039 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 EOO01188.1 - 0.0043 16.5 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 EOO01188.1 - 0.026 14.4 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 EOO01188.1 - 0.03 12.9 0.0 0.051 12.1 0.0 1.3 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CheR PF01739.18 EOO01188.1 - 0.069 12.6 0.0 7.3 6.0 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_3 PF01596.17 EOO01188.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase Cpn60_TCP1 PF00118.24 EOO01189.1 - 4.5e-153 510.4 15.0 5.2e-153 510.2 15.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mei5 PF10376.9 EOO01189.1 - 0.098 12.5 2.5 0.22 11.4 0.4 2.3 2 0 0 2 2 2 0 Double-strand recombination repair protein SUR7 PF06687.12 EOO01190.1 - 2.4e-19 69.8 0.0 2.6e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 EOO01190.1 - 3.7e-07 30.3 0.4 5.7e-07 29.6 0.4 1.2 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 CLLAC PF15675.5 EOO01190.1 - 0.37 10.4 3.1 0.84 9.2 3.1 1.6 1 0 0 1 1 1 0 CLLAC-motif containing domain NMT1 PF09084.11 EOO01191.1 - 6.5e-08 32.8 0.0 9.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 EOO01191.1 - 2.9e-05 23.8 0.1 4.1e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein GP57 PF17594.2 EOO01191.1 - 0.11 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 NMT1_2 PF13379.6 EOO01191.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.6 1 1 0 1 1 1 0 NMT1-like family OpuAC PF04069.12 EOO01191.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system MAD PF05557.13 EOO01192.1 - 1.2e-66 225.5 71.1 1.7e-66 225.0 45.0 2.1 1 1 1 2 2 2 2 Mitotic checkpoint protein PhoU PF01895.19 EOO01192.1 - 0.72 10.3 0.0 0.72 10.3 0.0 5.9 7 1 0 7 7 7 0 PhoU domain Fez1 PF06818.15 EOO01192.1 - 5.9 7.3 90.1 4.9 7.5 30.5 5.0 1 1 3 4 4 4 0 Fez1 Sugar_tr PF00083.24 EOO01193.1 - 6.4e-110 368.1 24.4 7.4e-110 367.9 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO01193.1 - 2.6e-22 79.2 33.6 1.2e-14 54.1 20.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EOO01193.1 - 2.2e-08 33.0 8.8 2.7e-05 22.8 4.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Lipase_GDSL_2 PF13472.6 EOO01194.1 - 8.8e-20 71.8 0.0 1.2e-19 71.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EOO01194.1 - 2.8e-11 43.8 0.0 4.5e-11 43.1 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 EOO01194.1 - 2.5e-05 23.6 0.0 3.7e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 OSK domain Lipase_GDSL_3 PF14606.6 EOO01194.1 - 8.9e-05 22.7 0.0 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SNF2_N PF00176.23 EOO01195.1 - 2.2e-65 220.7 0.6 5e-65 219.5 0.1 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EOO01195.1 - 1.4e-22 80.1 0.0 7.1e-22 77.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO01195.1 - 1.2e-06 28.7 0.2 4.9e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EOO01195.1 - 0.0004 19.6 1.0 0.0077 15.4 0.0 2.8 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 EOO01195.1 - 0.00078 18.7 0.0 0.00078 18.7 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 EOO01195.1 - 0.013 15.2 1.3 0.023 14.3 0.0 2.1 3 0 0 3 3 3 0 SWI2/SNF2 ATPase Ndc1_Nup PF09531.10 EOO01195.1 - 0.17 10.6 8.0 0.3 9.7 8.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.16 EOO01196.1 - 3.5e-11 42.6 32.7 3.5e-11 42.6 32.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EOO01196.1 - 9.5e-11 41.7 6.0 9.5e-11 41.7 6.0 3.3 4 1 1 5 5 5 1 Ion channel regulatory protein UNC-93 Aldedh PF00171.22 EOO01197.1 - 7.8e-125 417.0 2.3 1e-124 416.6 2.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Iso_dh PF00180.20 EOO01197.1 - 3.4e-87 292.8 0.0 4.6e-87 292.4 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SAC3_GANP PF03399.16 EOO01198.1 - 6.7e-26 91.3 3.4 6.9e-24 84.7 3.4 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EOO01198.1 - 0.048 13.6 0.1 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family Rieske PF00355.26 EOO01199.1 - 3.1e-11 43.1 0.0 5.7e-11 42.2 0.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 EOO01199.1 - 3.9e-09 36.8 0.1 8.4e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Peptidase_M28 PF04389.17 EOO01200.1 - 6e-30 104.4 0.0 8.8e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EOO01200.1 - 2.5e-06 27.4 0.0 4.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HTH_ABP1_N PF18107.1 EOO01201.1 - 3.1e-24 84.4 0.6 3.1e-24 84.4 0.6 2.0 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 EOO01201.1 - 8.1e-17 61.0 2.2 2.7e-16 59.4 0.3 2.5 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain YdfA_immunity PF12127.8 EOO01201.1 - 0.57 9.2 1.9 1.8 7.6 1.9 1.7 1 1 0 1 1 1 0 SigmaW regulon antibacterial DUF737 PF05300.11 EOO01201.1 - 7.9 6.8 6.3 4 7.7 3.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF737) SOR_SNZ PF01680.17 EOO01203.1 - 3.7e-106 353.5 7.0 4.8e-106 353.1 7.0 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EOO01203.1 - 5.3e-09 35.8 6.3 5.6e-07 29.1 0.3 2.6 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EOO01203.1 - 0.00021 20.5 0.2 0.24 10.4 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 EOO01203.1 - 0.00039 20.4 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain IGPS PF00218.21 EOO01203.1 - 0.00095 18.4 0.2 0.029 13.5 0.0 2.5 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 EOO01203.1 - 0.0015 18.0 0.6 0.26 10.7 0.0 2.9 2 1 1 3 3 3 1 Histidine biosynthesis protein NanE PF04131.14 EOO01203.1 - 0.0038 16.4 0.5 0.086 12.0 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase OMPdecase PF00215.24 EOO01203.1 - 0.011 15.3 0.3 0.68 9.5 0.0 2.4 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family TMP-TENI PF02581.17 EOO01203.1 - 0.026 13.8 0.3 1.2 8.4 0.1 2.5 2 0 0 2 2 2 0 Thiamine monophosphate synthase NMO PF03060.15 EOO01203.1 - 0.029 13.8 8.8 0.064 12.6 1.4 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase zf-C2H2_jaz PF12171.8 EOO01204.1 - 9.5e-08 32.1 0.1 2e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EOO01204.1 - 2.4e-05 24.6 0.3 4.2e-05 23.8 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 EOO01204.1 - 0.0009 19.3 0.4 0.0033 17.4 0.4 2.0 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-DBF PF07535.12 EOO01204.1 - 0.0056 16.8 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 DBF zinc finger DUF3530 PF12048.8 EOO01204.1 - 0.084 12.3 0.0 0.084 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Atg14 PF10186.9 EOO01204.1 - 0.52 9.4 6.3 0.95 8.5 6.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Hus1 PF04005.12 EOO01204.1 - 0.96 8.5 3.1 1.5 7.9 3.1 1.2 1 0 0 1 1 1 0 Hus1-like protein Stathmin PF00836.19 EOO01204.1 - 2.2 8.2 21.1 0.19 11.7 13.9 2.1 2 0 0 2 2 2 0 Stathmin family Cation_efflux PF01545.21 EOO01205.1 - 2e-49 168.1 3.4 2.6e-49 167.7 3.4 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 EOO01205.1 - 0.0081 15.4 22.0 0.029 13.6 18.5 2.3 1 1 1 2 2 2 2 ZIP Zinc transporter Anoctamin PF04547.12 EOO01205.1 - 0.21 10.4 0.0 0.34 9.7 0.0 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel 4HBT PF03061.22 EOO01206.1 - 1.7e-06 28.3 0.1 2.9e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF2069 PF09842.9 EOO01206.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2069) Sas10_Utp3 PF04000.15 EOO01207.1 - 3.1e-17 63.0 2.1 3.1e-17 63.0 2.1 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family CDV3 PF15359.6 EOO01207.1 - 0.082 13.4 4.5 0.2 12.2 4.5 1.6 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Dsh_C PF12316.8 EOO01207.1 - 0.96 9.8 6.8 0.16 12.4 2.9 1.6 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Aldo_ket_red PF00248.21 EOO01208.1 - 1.1e-68 231.6 0.1 1.4e-68 231.3 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tom5 PF10642.9 EOO01208.1 - 0.0039 17.2 0.3 0.0082 16.2 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase ATP-sulfurylase PF01747.17 EOO01208.1 - 0.097 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 ATP-sulfurylase Rax2 PF12768.7 EOO01209.1 - 0.00041 19.9 0.0 0.00058 19.4 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity SKG6 PF08693.10 EOO01209.1 - 0.00084 18.7 3.2 0.0018 17.6 3.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF347 PF03988.12 EOO01209.1 - 0.025 14.8 0.7 0.046 13.9 0.7 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Mid2 PF04478.12 EOO01209.1 - 0.028 14.2 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Yip1 PF04893.17 EOO01209.1 - 0.047 13.4 0.1 0.099 12.4 0.2 1.5 2 0 0 2 2 2 0 Yip1 domain Syndecan PF01034.20 EOO01209.1 - 0.068 13.1 0.6 0.13 12.2 0.6 1.4 1 0 0 1 1 1 0 Syndecan domain FAD_binding_4 PF01565.23 EOO01210.1 - 2e-25 89.1 1.0 3.6e-25 88.3 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EOO01210.1 - 9.8e-07 28.8 0.0 1.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EOO01210.1 - 0.0041 16.6 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding E_Pc_C PF06752.12 EOO01211.1 - 4.3 7.4 18.7 6.7 6.8 18.7 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus RAP1 PF07218.11 EOO01211.1 - 9.8 4.3 10.1 10 4.2 10.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AFG1_ATPase PF03969.16 EOO01212.1 - 2.6e-97 326.0 0.0 8.4e-93 311.1 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EOO01212.1 - 2e-05 25.1 0.1 0.062 13.7 0.0 3.0 2 1 0 3 3 3 2 AAA ATPase domain Bac_DnaA PF00308.18 EOO01212.1 - 0.00017 21.5 0.5 0.6 9.9 0.0 2.7 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_22 PF13401.6 EOO01212.1 - 0.0015 18.8 0.1 0.051 13.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EOO01212.1 - 0.0038 17.2 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EOO01212.1 - 0.0039 17.6 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EOO01212.1 - 0.0049 16.9 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 EOO01212.1 - 0.011 15.8 0.0 0.029 14.4 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EOO01212.1 - 0.026 15.0 0.0 13 6.3 0.0 2.6 2 1 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 EOO01212.1 - 0.048 14.0 0.0 0.2 12.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 EOO01212.1 - 0.056 13.4 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain UvrD-helicase PF00580.21 EOO01212.1 - 0.083 12.4 0.0 0.17 11.3 0.0 1.4 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Pyrid_ox_like PF16242.5 EOO01213.1 - 2e-23 82.6 0.0 3e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 EOO01213.1 - 1.2e-10 41.4 0.0 2.6e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 EOO01213.1 - 0.0069 16.1 0.0 0.012 15.4 0.0 1.3 1 1 0 1 1 1 1 Putative FMN-binding domain DUF1449 PF07290.11 EOO01213.1 - 0.032 13.9 0.2 0.056 13.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) p450 PF00067.22 EOO01214.1 - 5.3e-36 124.4 0.0 9.6e-36 123.5 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 NDT80_PhoG PF05224.12 EOO01215.1 - 1.2e-46 159.3 0.0 2.1e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Peptidase_M3 PF01432.20 EOO01216.1 - 1.1e-158 529.3 0.0 1.4e-158 529.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M2 PF01401.18 EOO01216.1 - 0.15 10.7 0.0 0.53 8.8 0.0 1.8 2 0 0 2 2 2 0 Angiotensin-converting enzyme Peptidase_M91 PF14891.6 EOO01216.1 - 0.15 12.3 0.1 0.83 10.0 0.0 2.1 2 0 0 2 2 2 0 Effector protein Acyl-CoA_dh_N PF02771.16 EOO01217.1 - 2e-16 60.6 0.1 1.2e-15 58.1 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EOO01217.1 - 9.9e-16 58.3 0.9 1.6e-15 57.6 0.7 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EOO01217.1 - 0.0041 17.3 0.0 0.0076 16.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EOO01217.1 - 0.034 14.4 0.5 0.058 13.7 0.5 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain tRNA_bind PF01588.20 EOO01218.1 - 3.9e-23 81.4 0.2 1.4e-22 79.6 0.2 2.0 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 EOO01218.1 - 0.0015 18.7 1.8 0.0044 17.2 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EOO01218.1 - 0.0028 17.7 0.0 0.0064 16.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SMC_hinge PF06470.13 EOO01218.1 - 0.0045 17.3 1.8 0.0091 16.3 1.8 1.5 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain GST_C_3 PF14497.6 EOO01218.1 - 0.06 13.6 0.2 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EOO01218.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Rotamase_2 PF13145.6 EOO01218.1 - 1.6 9.5 19.9 0.86 10.4 8.3 2.7 2 1 1 3 3 3 0 PPIC-type PPIASE domain DUF1682 PF07946.14 EOO01218.1 - 7.3 5.7 7.0 10 5.2 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Glyco_hydro_72 PF03198.14 EOO01219.1 - 1e-66 225.4 0.9 1.2e-66 225.1 0.9 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EOO01219.1 - 1.5e-05 24.6 0.1 0.00037 20.0 0.1 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Swi5 PF07061.11 EOO01220.1 - 6e-19 67.9 0.6 1.2e-18 67.0 0.2 1.8 2 0 0 2 2 2 1 Swi5 RIC1 PF07064.13 EOO01220.1 - 0.019 14.4 0.5 0.029 13.8 0.3 1.4 2 0 0 2 2 2 0 RIC1 GvpK PF05121.12 EOO01220.1 - 0.063 13.3 1.3 0.089 12.8 0.4 1.7 2 0 0 2 2 2 0 Gas vesicle protein K ComA PF02679.15 EOO01221.1 - 9.2e-85 284.0 0.0 1.1e-84 283.7 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) Smr PF01713.21 EOO01221.1 - 0.08 13.3 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Smr domain FliX PF10768.9 EOO01222.1 - 0.029 14.9 0.3 0.069 13.7 0.0 1.7 2 0 0 2 2 2 0 Class II flagellar assembly regulator DUF5617 PF18493.1 EOO01222.1 - 0.053 13.6 0.1 0.17 12.0 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5617) Glyco_transf_28 PF03033.20 EOO01223.1 - 6.2e-17 61.9 0.2 8.9e-12 45.2 0.0 2.8 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EOO01223.1 - 0.00028 19.8 0.0 0.00049 19.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UIM PF02809.20 EOO01223.1 - 0.034 14.1 8.2 0.59 10.2 1.3 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif ATG_C PF09333.11 EOO01223.1 - 0.038 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain Meth_synt_2 PF01717.18 EOO01224.1 - 1.3e-14 54.3 0.0 1.7e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EOO01224.1 - 0.056 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain LRR_6 PF13516.6 EOO01225.1 - 1.6e-16 58.9 16.6 0.68 10.1 0.0 12.0 12 0 0 12 12 12 6 Leucine Rich repeat F-box-like PF12937.7 EOO01225.1 - 1.5e-12 47.2 4.1 4.2e-12 45.8 1.2 2.7 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EOO01225.1 - 6.7e-10 39.1 10.8 0.066 13.7 0.0 6.8 6 1 0 6 6 6 3 Leucine Rich repeats (2 copies) F-box PF00646.33 EOO01225.1 - 6.7e-06 25.8 0.1 3.6e-05 23.5 0.1 2.3 1 0 0 1 1 1 1 F-box domain DUF1699 PF08004.11 EOO01225.1 - 0.077 12.7 0.8 4 7.1 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1699) LRR_1 PF00560.33 EOO01225.1 - 1.4 9.8 16.2 1.4e+02 3.6 0.1 8.0 8 1 0 8 8 8 0 Leucine Rich Repeat DCP1 PF06058.13 EOO01226.1 - 2e-32 111.6 0.0 2.8e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family Exo_endo_phos PF03372.23 EOO01227.1 - 2.6e-07 30.4 0.2 6.3e-07 29.1 0.1 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Hydantoinase_B PF02538.14 EOO01228.1 - 3.8e-214 711.9 0.1 5.4e-214 711.4 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EOO01228.1 - 5.3e-105 350.8 0.2 1.3e-104 349.6 0.0 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EOO01228.1 - 1e-57 194.7 1.4 1.6e-56 190.8 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MARVEL PF01284.23 EOO01229.1 - 3.5e-07 30.3 15.7 5e-07 29.8 15.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 EOO01229.1 - 3.6 5.8 9.3 4.4 5.5 9.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1479 PF07350.12 EOO01230.1 - 1e-21 77.2 0.0 1.3e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Glyco_transf_90 PF05686.12 EOO01231.1 - 1.4e-12 47.3 4.0 5.4e-11 42.0 0.0 3.0 3 0 0 3 3 3 2 Glycosyl transferase family 90 Ank_4 PF13637.6 EOO01232.1 - 2.2e-09 37.7 0.6 0.012 16.2 0.1 5.6 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 EOO01232.1 - 2.1e-08 34.3 5.7 0.44 11.1 0.0 6.9 7 0 0 7 7 7 2 Ankyrin repeat Ank_3 PF13606.6 EOO01232.1 - 3.9e-07 29.9 8.7 3.8 8.4 0.0 7.5 10 0 0 10 10 10 3 Ankyrin repeat Ank_2 PF12796.7 EOO01232.1 - 6.9e-07 29.8 0.2 0.0088 16.6 0.0 4.8 3 2 2 5 5 5 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EOO01232.1 - 1.2e-06 28.7 3.9 0.23 11.8 0.1 5.8 4 2 2 6 6 6 2 Ankyrin repeats (many copies) CorA PF01544.18 EOO01233.1 - 0.0055 16.1 0.1 0.022 14.1 0.1 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Lactamase_B PF00753.27 EOO01235.1 - 4e-05 23.7 0.1 5.3e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EOO01235.1 - 0.012 15.1 0.2 0.018 14.6 0.2 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Glyco_hydro_3_C PF01915.22 EOO01236.1 - 1.6e-58 198.0 0.0 3.4e-58 197.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EOO01236.1 - 4.6e-40 138.0 0.0 8.2e-40 137.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EOO01236.1 - 1.8e-18 66.4 0.4 4.1e-18 65.2 0.2 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain Phage_tail_X PF05489.12 EOO01236.1 - 0.11 12.2 0.3 0.28 10.9 0.3 1.7 1 0 0 1 1 1 0 Phage Tail Protein X Peptidase_S8 PF00082.22 EOO01237.1 - 2.3e-36 125.6 0.0 4.5e-36 124.6 0.0 1.4 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EOO01237.1 - 1.8e-06 28.6 0.0 4e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain Methyltransf_25 PF13649.6 EOO01238.1 - 0.00085 20.0 0.0 0.0018 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EOO01238.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Pectinesterase PF01095.19 EOO01239.1 - 4.2e-72 242.4 25.3 1.8e-36 125.4 2.0 4.8 4 1 1 5 5 5 5 Pectinesterase MFS_1 PF07690.16 EOO01240.1 - 6.6e-31 107.5 23.2 6.6e-31 107.5 23.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3827 PF12877.7 EOO01240.1 - 0.26 9.6 1.4 0.35 9.2 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) DUF21 PF01595.20 EOO01240.1 - 0.44 10.2 6.1 0.6 9.8 2.5 2.6 1 1 0 2 2 2 0 Cyclin M transmembrane N-terminal domain HeLo PF14479.6 EOO01241.1 - 4.6e-47 160.5 0.0 8.1e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation TPR_1 PF00515.28 EOO01241.1 - 4.3e-12 45.3 9.4 5.2e-06 26.1 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EOO01241.1 - 1.6e-10 40.3 9.2 0.00022 21.1 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EOO01241.1 - 8.8e-09 34.9 2.2 3.1e-05 23.6 0.3 3.4 2 1 1 3 3 3 3 TPR repeat TPR_16 PF13432.6 EOO01241.1 - 1.6e-06 28.6 5.4 0.00011 22.7 0.5 2.6 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EOO01241.1 - 3.5e-06 26.8 5.6 0.026 14.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EOO01241.1 - 0.0002 21.6 2.7 0.23 11.8 0.9 3.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EOO01241.1 - 0.00071 20.2 1.0 0.52 11.3 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EOO01241.1 - 0.00071 19.4 0.1 0.17 12.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EOO01241.1 - 0.013 15.9 0.5 5.2 7.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EOO01241.1 - 0.017 15.7 3.9 0.85 10.4 0.5 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EOO01241.1 - 0.06 13.2 3.7 2.4 8.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EOO01241.1 - 0.17 12.5 4.7 3.9 8.0 0.2 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EOO01241.1 - 0.3 11.2 3.4 0.22 11.6 0.7 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Ribosomal_S26e PF01283.19 EOO01242.1 - 2.2e-51 172.8 8.7 2.6e-51 172.6 8.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 EOO01242.1 - 0.02 14.9 0.4 0.056 13.4 0.0 1.9 2 0 0 2 2 2 0 Zinc binding domain DUF1918 PF08940.11 EOO01242.1 - 0.032 13.8 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) DUF4668 PF15701.5 EOO01242.1 - 0.2 11.5 1.8 0.25 11.1 1.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) DUF2278 PF10042.9 EOO01243.1 - 2.6e-69 233.4 0.0 3.4e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) LTD PF00932.19 EOO01243.1 - 4.8e-09 36.6 0.0 1.3e-08 35.2 0.0 1.7 2 0 0 2 2 2 1 Lamin Tail Domain Cys_Met_Meta_PP PF01053.20 EOO01244.1 - 2.6e-141 470.6 0.0 3e-141 470.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EOO01244.1 - 1.9e-08 33.7 0.1 3.1e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EOO01244.1 - 2.8e-08 33.5 0.1 6.4e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EOO01244.1 - 9.3e-08 31.6 0.1 1.4e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EOO01244.1 - 0.00043 19.6 0.1 0.0011 18.4 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 EOO01244.1 - 0.0036 15.9 0.0 0.0048 15.5 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SepSecS PF05889.13 EOO01244.1 - 0.0062 15.3 0.1 0.0094 14.7 0.1 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS ADH_zinc_N PF00107.26 EOO01244.1 - 0.036 14.0 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase GDC-P PF02347.16 EOO01244.1 - 0.053 12.3 0.0 0.073 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Abhydrolase_6 PF12697.7 EOO01245.1 - 7.8e-08 33.2 0.0 8.9e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EOO01245.1 - 0.00087 18.6 0.3 0.056 12.7 0.5 2.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EOO01245.1 - 0.056 12.9 0.1 0.62 9.5 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family RTP PF02334.16 EOO01245.1 - 0.17 12.5 0.1 0.31 11.7 0.1 1.3 1 0 0 1 1 1 0 Replication terminator protein Pox_I6 PF04595.13 EOO01245.1 - 0.2 10.6 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus I6-like family MFS_1 PF07690.16 EOO01246.1 - 4.3e-16 58.8 39.7 2.1e-13 49.9 17.9 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily YoqO PF14037.6 EOO01246.1 - 0.4 11.2 4.0 0.28 11.7 0.8 2.4 2 0 0 2 2 2 0 YoqO-like protein DUF3290 PF11694.8 EOO01246.1 - 3.1 7.8 6.6 0.34 10.9 0.9 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) UDPGT PF00201.18 EOO01247.1 - 6.7e-06 25.2 0.0 2.2e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase MFS_1 PF07690.16 EOO01248.1 - 1.8e-35 122.5 31.1 1.8e-35 122.5 31.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Neurensin PF14927.6 EOO01248.1 - 0.11 12.2 1.4 14 5.4 0.0 3.2 4 0 0 4 4 4 0 Neurensin CoA_trans PF01144.23 EOO01249.1 - 3.8e-99 330.5 0.5 5.6e-59 199.2 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 EOO01249.1 - 0.0003 20.8 0.2 0.00068 19.6 0.2 1.6 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 EOO01249.1 - 0.097 11.0 0.9 0.14 10.5 0.2 1.5 1 1 1 2 2 2 0 Malonate decarboxylase, alpha subunit, transporter JUPITER PF17054.5 EOO01250.1 - 0.023 14.2 0.4 0.028 13.9 0.4 1.2 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter Aldo_ket_red PF00248.21 EOO01251.1 - 1.5e-71 241.0 0.0 1.7e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Arginase PF00491.21 EOO01252.1 - 1.6e-75 254.2 0.1 1.9e-75 253.9 0.1 1.0 1 0 0 1 1 1 1 Arginase family Aldo_ket_red PF00248.21 EOO01253.1 - 1.1e-11 44.5 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 EOO01254.1 - 2e-05 24.6 9.5 2e-05 24.6 9.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_4 PF13637.6 EOO01255.1 - 9.2e-48 160.0 0.0 2.9e-07 30.9 0.0 9.8 3 1 7 10 10 10 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 EOO01255.1 - 5e-47 158.4 0.0 6.1e-12 46.0 0.0 5.2 3 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EOO01255.1 - 2.2e-40 132.0 0.1 0.011 16.2 0.0 11.8 12 0 0 12 12 12 9 Ankyrin repeat Ank PF00023.30 EOO01255.1 - 8.8e-40 133.5 6.8 0.0024 18.2 0.1 12.1 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.6 EOO01255.1 - 1.6e-38 130.3 1.0 6.6e-06 26.3 0.0 8.3 4 4 4 8 8 8 8 Ankyrin repeats (many copies) OpuAC PF04069.12 EOO01255.1 - 0.036 13.6 0.0 5.7 6.4 0.0 3.0 1 1 2 3 3 3 0 Substrate binding domain of ABC-type glycine betaine transport system Lyase_1 PF00206.20 EOO01256.1 - 9.7e-21 74.5 0.0 1.5e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EOO01256.1 - 6.7e-14 52.2 0.0 2e-13 50.6 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus MFS_1 PF07690.16 EOO01257.1 - 6e-34 117.5 27.6 6e-34 117.5 27.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EOO01257.1 - 0.00053 19.7 1.9 0.0014 18.4 1.9 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 TraT PF05818.12 EOO01257.1 - 1.7 8.3 4.3 0.63 9.7 0.9 2.0 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein Glyco_hydro_3_C PF01915.22 EOO01258.1 - 5.9e-47 160.3 0.0 9.2e-47 159.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EOO01258.1 - 2.5e-26 92.8 0.0 3.9e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EOO01258.1 - 2.6e-25 88.3 0.1 4.7e-25 87.5 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain FAD_binding_3 PF01494.19 EOO01259.1 - 5e-17 62.2 0.0 9.3e-17 61.3 0.0 1.3 2 0 0 2 2 2 1 FAD binding domain FCH PF00611.23 EOO01259.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Bac_rhamnosid6H PF17389.2 EOO01261.1 - 2.3e-59 201.4 0.0 2.8e-44 151.8 0.0 2.4 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 EOO01261.1 - 6.4e-45 153.1 0.9 1.9e-44 151.5 0.0 2.2 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid_C PF17390.2 EOO01261.1 - 2.3e-13 49.8 0.1 5.7e-13 48.5 0.1 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid PF05592.11 EOO01261.1 - 2.8e-13 49.7 0.0 5.1e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain DUF1793 PF08760.11 EOO01261.1 - 0.069 13.6 0.2 0.17 12.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1793) Tyrosinase PF00264.20 EOO01262.1 - 2.6e-46 158.7 0.1 3.8e-46 158.1 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Fungal_trans PF04082.18 EOO01263.1 - 7.4e-23 80.9 0.0 9.3e-22 77.3 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Tcp11 PF05794.13 EOO01263.1 - 0.044 12.9 0.0 0.06 12.4 0.0 1.1 1 0 0 1 1 1 0 T-complex protein 11 Cnn_1N PF07989.11 EOO01264.1 - 7e-22 77.4 6.0 7e-22 77.4 6.0 11.3 9 2 4 13 13 13 2 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 EOO01264.1 - 2.1e-07 31.1 5.1 2.1e-07 31.1 5.1 12.3 12 1 0 12 12 12 3 Micro-tubular organiser Mto1 C-term Mto2-binding region APG6_N PF17675.1 EOO01264.1 - 0.013 16.0 0.9 0.013 16.0 0.9 11.2 5 3 6 12 12 12 0 Apg6 coiled-coil region ubiquitin PF00240.23 EOO01265.1 - 5e-34 115.9 1.0 7.9e-34 115.2 0.6 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 EOO01265.1 - 9.6e-27 92.9 1.8 9.6e-27 92.9 1.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EOO01265.1 - 2.4e-16 59.3 0.7 4.9e-16 58.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EOO01265.1 - 2.4e-05 24.7 0.5 0.00013 22.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EOO01265.1 - 0.00071 19.6 0.7 0.0016 18.5 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EOO01265.1 - 0.0044 17.3 0.9 0.0076 16.6 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EOO01265.1 - 0.0054 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EOO01265.1 - 0.01 16.4 0.7 0.014 15.9 0.7 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EOO01265.1 - 0.019 15.0 1.0 5.9 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain FA_desaturase PF00487.24 EOO01267.1 - 5.3e-25 88.7 25.9 5.3e-25 88.7 25.9 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EOO01267.1 - 6.7e-05 23.1 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Ank_2 PF12796.7 EOO01268.1 - 7.1e-21 74.6 2.8 8.6e-11 42.3 0.7 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EOO01268.1 - 3.4e-16 59.4 10.9 1.6e-07 31.8 0.7 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EOO01268.1 - 5.5e-16 58.4 8.3 4.4e-07 30.1 0.2 4.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EOO01268.1 - 7.6e-15 53.5 4.9 0.0013 19.1 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EOO01268.1 - 5.1e-14 52.0 8.0 0.00013 22.3 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat BON PF04972.17 EOO01268.1 - 0.11 12.8 0.4 0.23 11.8 0.4 1.5 1 0 0 1 1 1 0 BON domain Porphobil_deamC PF03900.15 EOO01268.1 - 0.11 12.8 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 Porphobilinogen deaminase, C-terminal domain Prefoldin_2 PF01920.20 EOO01269.1 - 1.3e-21 76.5 15.2 1.6e-21 76.2 15.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 EOO01269.1 - 0.00032 20.6 11.8 0.00053 19.9 1.6 2.2 2 0 0 2 2 2 1 Prefoldin subunit DivIC PF04977.15 EOO01269.1 - 0.0011 18.7 18.3 0.011 15.5 3.1 3.0 2 1 1 3 3 3 2 Septum formation initiator Prefoldin_3 PF13758.6 EOO01269.1 - 0.0017 18.4 5.1 0.0026 17.8 5.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit Spc24 PF08286.11 EOO01269.1 - 0.0019 18.4 11.7 0.13 12.6 3.6 2.1 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 PHM7_cyt PF14703.6 EOO01269.1 - 0.0022 18.2 7.3 0.0035 17.6 7.3 1.4 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter COG5 PF10392.9 EOO01269.1 - 0.0031 17.7 2.5 0.3 11.3 0.1 2.2 2 0 0 2 2 2 1 Golgi transport complex subunit 5 MIP-T3_C PF17749.1 EOO01269.1 - 0.004 17.1 2.6 0.004 17.1 2.6 2.2 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region Fez1 PF06818.15 EOO01269.1 - 0.0042 17.6 10.0 0.012 16.1 2.0 2.1 2 0 0 2 2 2 1 Fez1 Siah-Interact_N PF09032.11 EOO01269.1 - 0.0059 16.9 12.6 0.26 11.6 1.7 2.2 2 0 0 2 2 2 2 Siah interacting protein, N terminal MAD PF05557.13 EOO01269.1 - 0.0063 14.9 11.3 0.0068 14.8 11.3 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein YabA PF06156.13 EOO01269.1 - 0.012 16.3 6.8 0.67 10.6 1.0 2.1 2 0 0 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 EOO01269.1 - 0.015 15.8 16.4 0.1 13.0 7.1 2.1 2 0 0 2 2 2 0 Cell division protein ZapB NPV_P10 PF05531.12 EOO01269.1 - 0.017 15.6 8.7 0.15 12.6 2.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein K-box PF01486.17 EOO01269.1 - 0.021 15.0 9.0 0.077 13.2 0.5 2.2 2 0 0 2 2 2 0 K-box region DUF745 PF05335.13 EOO01269.1 - 0.033 13.9 1.4 0.033 13.9 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) HSBP1 PF06825.12 EOO01269.1 - 0.033 14.0 1.3 0.31 10.9 0.4 2.5 2 1 0 2 2 2 0 Heat shock factor binding protein 1 SKA2 PF16740.5 EOO01269.1 - 0.039 13.7 9.9 0.037 13.8 2.7 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 YtxC PF08812.11 EOO01269.1 - 0.04 13.5 4.1 0.049 13.2 4.1 1.1 1 0 0 1 1 1 0 YtxC-like family Spc7 PF08317.11 EOO01269.1 - 0.044 12.7 15.2 0.064 12.1 15.2 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.5 EOO01269.1 - 0.045 14.0 12.2 0.15 12.4 12.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF4201 PF13870.6 EOO01269.1 - 0.055 13.2 12.5 0.28 10.9 2.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Gon7 PF08738.10 EOO01269.1 - 0.056 13.5 6.2 0.42 10.7 1.7 2.1 2 0 0 2 2 2 0 Gon7 family DHR10 PF18595.1 EOO01269.1 - 0.071 13.2 13.6 0.91 9.6 5.3 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF885 PF05960.11 EOO01269.1 - 0.077 12.6 3.9 0.092 12.4 3.9 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) LPP PF04728.13 EOO01269.1 - 0.079 13.4 7.4 0.29 11.6 1.1 2.7 2 1 0 2 2 2 0 Lipoprotein leucine-zipper LIF_OSM PF01291.17 EOO01269.1 - 0.079 13.1 2.0 2.8 8.1 0.1 2.1 2 0 0 2 2 2 0 LIF / OSM family CENP-H PF05837.12 EOO01269.1 - 0.086 13.3 10.1 0.45 10.9 1.1 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) TMF_TATA_bd PF12325.8 EOO01269.1 - 0.091 13.0 8.5 0.68 10.2 3.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DASH_Dad4 PF08650.10 EOO01269.1 - 0.1 12.6 1.5 10 6.2 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad4 FliD_C PF07195.12 EOO01269.1 - 0.11 11.9 7.0 0.23 10.8 7.0 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus BRE1 PF08647.11 EOO01269.1 - 0.12 12.5 14.1 0.15 12.2 2.6 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase GPHR_N PF12537.8 EOO01269.1 - 0.13 12.3 1.0 0.19 11.8 0.1 1.8 2 0 0 2 2 1 0 The Golgi pH Regulator (GPHR) Family N-terminal ABC_tran_CTD PF16326.5 EOO01269.1 - 0.15 12.3 14.4 0.16 12.3 1.8 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain FlaC_arch PF05377.11 EOO01269.1 - 0.18 12.2 9.5 2.7 8.5 0.5 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) GAS PF13851.6 EOO01269.1 - 0.21 10.9 16.3 3.2 7.0 16.3 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Uso1_p115_C PF04871.13 EOO01269.1 - 0.24 11.8 12.7 0.41 11.0 4.4 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4407 PF14362.6 EOO01269.1 - 0.25 10.7 10.1 0.64 9.3 10.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC144C PF14915.6 EOO01269.1 - 0.27 10.3 14.0 8.2 5.4 14.0 2.1 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region DUF5497 PF17601.2 EOO01269.1 - 0.29 11.5 2.8 0.29 11.5 0.4 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5497) Wtap PF17098.5 EOO01269.1 - 0.32 10.9 9.9 1.8 8.5 9.9 1.9 1 1 0 1 1 1 0 WTAP/Mum2p family TPR_MLP1_2 PF07926.12 EOO01269.1 - 0.33 11.0 15.8 1.7 8.7 4.8 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4164 PF13747.6 EOO01269.1 - 0.34 11.2 7.1 3.3 8.0 1.8 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) Rx_N PF18052.1 EOO01269.1 - 0.35 11.2 6.6 2.3 8.5 2.4 2.3 2 0 0 2 2 2 0 Rx N-terminal domain ERp29 PF07749.12 EOO01269.1 - 0.45 11.5 6.7 1.8 9.5 6.7 1.9 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain LCIB_C_CA PF18599.1 EOO01269.1 - 0.46 9.8 2.8 0.36 10.1 1.4 1.5 1 1 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases HrpB7 PF09486.10 EOO01269.1 - 0.5 10.7 8.1 0.27 11.6 1.3 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4315 PF14193.6 EOO01269.1 - 0.54 10.3 13.9 1.3 9.1 2.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) YlqD PF11068.8 EOO01269.1 - 0.6 10.5 18.3 0.72 10.2 5.6 2.0 1 1 1 2 2 2 0 YlqD protein Rootletin PF15035.6 EOO01269.1 - 0.7 9.9 11.9 4.2 7.4 4.9 2.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Rho_Binding PF08912.11 EOO01269.1 - 0.71 10.7 15.5 0.29 12.0 1.6 2.5 2 1 0 2 2 2 0 Rho Binding JIP_LZII PF16471.5 EOO01269.1 - 0.94 9.7 9.8 1.3 9.2 1.7 2.5 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 EOO01269.1 - 1 9.5 8.8 5.9 7.1 0.1 2.9 2 1 1 3 3 3 0 bZIP transcription factor Macoilin PF09726.9 EOO01269.1 - 1.2 7.6 11.7 11 4.5 11.7 1.8 1 1 0 1 1 1 0 Macoilin family YgaB PF14182.6 EOO01269.1 - 1.5 9.3 12.0 1.1 9.7 2.5 2.7 2 1 1 3 3 3 0 YgaB-like protein Swi5 PF07061.11 EOO01269.1 - 2.1 8.5 12.4 2.6 8.2 2.1 2.4 2 0 0 2 2 2 0 Swi5 DUF4337 PF14235.6 EOO01269.1 - 2.3 8.3 11.1 5.6 7.1 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) SKA1 PF07160.12 EOO01269.1 - 2.4 8.0 10.9 4.2 7.1 1.1 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 CCDC-167 PF15188.6 EOO01269.1 - 2.4 8.6 9.0 0.38 11.1 0.7 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF948 PF06103.11 EOO01269.1 - 2.5 8.4 7.2 5.6 7.3 0.8 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.8 EOO01269.1 - 2.8 7.2 15.1 0.63 9.3 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) USP8_interact PF08941.10 EOO01269.1 - 2.9 7.7 7.0 2 8.2 1.0 2.0 2 0 0 2 2 2 0 USP8 interacting DUF4140 PF13600.6 EOO01269.1 - 3.9 8.0 11.5 6.7 7.2 2.1 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2802 PF10975.8 EOO01269.1 - 4.6 7.4 9.5 2.8 8.1 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) Cep57_MT_bd PF06657.13 EOO01269.1 - 5.7 7.5 11.6 3 8.4 1.6 2.6 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 CHD5 PF04420.14 EOO01269.1 - 6.5 6.6 7.7 2.1 8.2 0.7 2.2 2 0 0 2 2 2 0 CHD5-like protein Atg14 PF10186.9 EOO01269.1 - 6.6 5.7 13.1 65 2.5 13.1 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 EOO01269.1 - 7.9 7.0 19.6 12 6.5 8.8 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Val_tRNA-synt_C PF10458.9 EOO01269.1 - 8.8 6.7 12.6 6.6 7.1 1.9 3.0 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm RraA-like PF03737.15 EOO01270.1 - 3.3e-33 115.0 0.0 1.5e-32 112.8 0.0 2.1 2 0 0 2 2 2 1 Aldolase/RraA adh_short_C2 PF13561.6 EOO01270.1 - 1.7e-23 83.4 0.0 2.7e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO01270.1 - 3e-17 62.7 0.0 5.1e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase MR_MLE_C PF13378.6 EOO01272.1 - 7.6e-44 149.9 0.0 1e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EOO01272.1 - 1.2e-08 35.2 0.0 2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DIOX_N PF14226.6 EOO01273.1 - 2.8e-27 95.8 0.2 4.4e-27 95.2 0.2 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EOO01273.1 - 3.8e-22 78.7 0.0 6.8e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2517 PF10725.9 EOO01273.1 - 0.12 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) TOH_N PF12549.8 EOO01273.1 - 0.12 12.2 0.0 0.37 10.7 0.0 1.9 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal AAA PF00004.29 EOO01274.1 - 5e-42 143.4 0.0 9.1e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EOO01274.1 - 6.8e-29 99.7 1.3 3e-28 97.6 0.6 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EOO01274.1 - 1e-22 80.0 4.0 2.9e-22 78.5 4.0 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EOO01274.1 - 6.8e-08 32.2 0.0 4.4e-07 29.6 0.0 2.5 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 EOO01274.1 - 1.6e-05 25.4 0.1 0.0013 19.1 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 EOO01274.1 - 1.7e-05 25.2 0.2 0.0034 17.7 0.0 2.8 3 0 0 3 3 2 1 RNA helicase RuvB_N PF05496.12 EOO01274.1 - 2e-05 24.4 0.0 4.1e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EOO01274.1 - 2.5e-05 24.3 0.0 0.00015 21.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EOO01274.1 - 2.7e-05 24.0 0.0 7.2e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EOO01274.1 - 4.2e-05 23.8 0.1 0.012 15.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 EOO01274.1 - 7e-05 22.2 0.0 0.00014 21.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 EOO01274.1 - 0.00015 21.8 0.0 0.00033 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EOO01274.1 - 0.00016 22.2 0.2 0.00072 20.1 0.0 2.2 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.13 EOO01274.1 - 0.00022 20.5 0.0 0.0013 17.9 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 EOO01274.1 - 0.00052 19.8 0.1 0.0034 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EOO01274.1 - 0.00063 19.9 0.0 0.0024 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EOO01274.1 - 0.00099 19.3 0.0 0.0062 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 EOO01274.1 - 0.0036 16.9 0.1 0.31 10.6 0.1 2.6 1 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EOO01274.1 - 0.0096 16.4 0.0 0.038 14.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 EOO01274.1 - 0.012 14.7 0.0 0.033 13.3 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 EOO01274.1 - 0.013 14.9 0.0 0.042 13.2 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EOO01274.1 - 0.016 14.8 0.1 0.1 12.1 0.0 2.4 3 1 0 3 3 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 EOO01274.1 - 0.026 15.0 0.5 0.62 10.6 0.0 2.9 3 1 0 3 3 2 0 ABC transporter Torsin PF06309.11 EOO01274.1 - 0.036 14.2 0.2 0.1 12.7 0.0 1.8 2 0 0 2 2 1 0 Torsin NACHT PF05729.12 EOO01274.1 - 0.039 13.9 0.0 0.2 11.6 0.0 2.0 1 1 1 2 2 2 0 NACHT domain ATPase PF06745.13 EOO01274.1 - 0.043 13.1 0.0 5.8 6.2 0.0 2.4 1 1 1 2 2 2 0 KaiC AAA_28 PF13521.6 EOO01274.1 - 0.049 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EOO01274.1 - 0.058 12.7 0.3 1.7 7.9 0.1 2.9 2 1 1 3 3 3 0 Zeta toxin Cytidylate_kin PF02224.18 EOO01274.1 - 0.067 12.9 0.2 0.64 9.7 0.1 2.3 2 0 0 2 2 2 0 Cytidylate kinase PhoH PF02562.16 EOO01274.1 - 0.072 12.5 0.1 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein CPT PF07931.12 EOO01274.1 - 0.091 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Guanylate_kin PF00625.21 EOO01274.1 - 0.1 12.3 0.0 0.39 10.4 0.0 2.0 1 0 0 1 1 1 0 Guanylate kinase Sigma54_activat PF00158.26 EOO01274.1 - 0.11 12.3 0.0 0.35 10.6 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EOO01274.1 - 0.17 12.0 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EOO01274.1 - 0.25 11.2 1.5 1.6 8.6 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea ACT_7 PF13840.6 EOO01275.1 - 7.2e-11 41.7 5.0 1.4e-08 34.4 3.0 2.2 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 EOO01275.1 - 4.9e-06 26.2 1.1 4.4e-05 23.1 0.3 2.6 2 1 0 2 2 2 1 ACT domain Nmad4 PF18756.1 EOO01275.1 - 0.051 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Nucleotide modification associated domain 4 DUF917 PF06032.12 EOO01276.1 - 6.9e-74 248.8 0.0 5e-40 137.4 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 EOO01276.1 - 0.0028 17.4 0.3 0.0047 16.7 0.3 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 EOO01276.1 - 0.027 13.1 0.5 0.038 12.6 0.5 1.2 1 0 0 1 1 1 0 MutL protein Hydantoinase_A PF01968.18 EOO01276.1 - 0.028 13.7 0.1 0.046 13.0 0.1 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Glyco_hydro_6 PF01341.17 EOO01277.1 - 1.5e-100 336.8 1.3 2e-100 336.5 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Adeno_E3_CR2 PF02439.15 EOO01278.1 - 0.0045 16.7 0.1 0.0073 16.0 0.1 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF485 PF04341.12 EOO01278.1 - 0.042 13.8 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 PepSY_TM PF03929.16 EOO01278.1 - 0.043 13.5 0.0 0.051 13.2 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Ank_2 PF12796.7 EOO01279.1 - 1.4e-08 35.2 0.2 2.5e-05 24.8 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EOO01279.1 - 2.8e-07 30.7 0.3 0.3 11.6 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EOO01279.1 - 6.1e-07 29.6 1.2 0.047 14.0 0.1 3.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EOO01279.1 - 2.4e-06 28.0 0.3 0.093 13.3 0.1 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EOO01279.1 - 0.018 15.5 0.1 80 4.3 0.0 4.3 4 0 0 4 4 4 0 Ankyrin repeat FMN_dh PF01070.18 EOO01280.1 - 2.9e-115 385.0 0.2 3.3e-115 384.8 0.2 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EOO01280.1 - 5.2e-06 25.7 0.1 1.8e-05 23.9 0.1 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EOO01280.1 - 0.00033 19.9 0.0 0.00051 19.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 EOO01280.1 - 0.00063 19.2 0.9 0.0019 17.7 0.3 1.9 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 EOO01280.1 - 0.001 18.6 0.0 0.014 14.8 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 EOO01280.1 - 0.011 15.1 0.1 0.25 10.6 0.0 2.7 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 EOO01280.1 - 0.16 11.1 0.1 1.5 7.9 0.0 2.5 2 1 1 3 3 3 0 Dihydroorotate dehydrogenase Paramyxo_ncap PF00973.19 EOO01281.1 - 0.27 10.1 0.9 0.37 9.6 0.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein 2-Hacid_dh_C PF02826.19 EOO01283.1 - 6.8e-28 97.2 0.0 1.1e-27 96.6 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain JAB PF01398.21 EOO01284.1 - 3.7e-14 52.7 0.0 7.8e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 EOO01284.1 - 8.1e-10 38.9 0.0 2e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 EOO01284.1 - 0.0012 18.6 0.0 0.0032 17.2 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain YabA PF06156.13 EOO01284.1 - 0.16 12.6 0.5 0.47 11.1 0.2 1.9 2 0 0 2 2 2 0 Initiation control protein YabA Nop PF01798.18 EOO01285.1 - 4.1e-82 275.1 0.0 9.2e-82 273.9 0.0 1.6 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EOO01285.1 - 1.4e-18 67.0 0.2 4.9e-18 65.3 0.2 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DNA_Packaging PF11053.8 EOO01285.1 - 0.022 14.6 1.5 0.031 14.1 0.3 1.9 2 0 0 2 2 2 0 Terminase DNA packaging enzyme RNA_polI_A34 PF08208.11 EOO01285.1 - 1.2 9.1 15.2 2.1 8.4 15.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Sugar_tr PF00083.24 EOO01286.1 - 2.9e-38 131.9 19.7 2.5e-27 95.8 10.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO01286.1 - 1.8e-06 27.1 29.1 0.00027 20.0 9.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1993 PF09351.10 EOO01287.1 - 3.1e-56 189.9 0.0 3.5e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Peptidase_M28 PF04389.17 EOO01289.1 - 2e-22 79.9 0.0 2.7e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EOO01289.1 - 0.00063 19.5 0.0 0.0008 19.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Glyco_hydro_18 PF00704.28 EOO01290.1 - 1.3e-90 304.3 0.2 1.6e-90 304.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PMBR PF09373.10 EOO01290.1 - 0.19 12.0 0.3 1.4 9.2 0.1 2.4 2 0 0 2 2 2 0 Pseudomurein-binding repeat 2-Hacid_dh_C PF02826.19 EOO01291.1 - 7.9e-52 175.2 0.0 1.4e-51 174.3 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EOO01291.1 - 1.9e-23 82.6 0.0 2.4e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EOO01291.1 - 0.0062 16.7 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EOO01291.1 - 0.019 14.6 0.1 0.075 12.6 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 EOO01291.1 - 0.06 13.9 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DHQ_synthase PF01761.20 EOO01292.1 - 3.4e-42 144.4 0.0 4.9e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EOO01292.1 - 3.1e-10 40.2 0.0 4.9e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 EOO01292.1 - 0.0086 14.9 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase MT0933_antitox PF14013.6 EOO01293.1 - 0.016 15.5 1.7 0.17 12.2 1.7 2.1 1 1 0 1 1 1 0 MT0933-like antitoxin protein PEP_mutase PF13714.6 EOO01294.1 - 1.5e-55 188.3 0.6 1.7e-55 188.1 0.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase AP_endonuc_2 PF01261.24 EOO01294.1 - 0.05 13.0 0.2 0.47 9.9 0.2 2.3 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Radical_SAM PF04055.21 EOO01294.1 - 0.068 13.5 0.1 2.1 8.7 0.1 2.2 1 1 0 1 1 1 0 Radical SAM superfamily NanE PF04131.14 EOO01294.1 - 0.098 11.8 0.4 0.6 9.3 0.4 2.1 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Amidohydro_2 PF04909.14 EOO01294.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase DeoC PF01791.9 EOO01295.1 - 2.9e-09 36.9 2.3 1.5e-08 34.6 2.3 1.9 1 1 0 1 1 1 1 DeoC/LacD family aldolase DUF4148 PF13663.6 EOO01295.1 - 0.13 12.4 0.9 0.38 11.0 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) MFS_1 PF07690.16 EOO01296.1 - 3.5e-36 124.9 51.9 9e-35 120.2 50.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF5353 PF17304.2 EOO01296.1 - 0.0039 16.9 0.3 0.0039 16.9 0.3 2.6 2 1 0 2 2 2 1 Family of unknown function (DUF5353) YwiC PF14256.6 EOO01296.1 - 0.019 15.3 3.7 0.019 15.3 3.7 3.4 3 1 1 4 4 4 0 YwiC-like protein MS_channel PF00924.18 EOO01296.1 - 0.069 12.7 1.8 0.25 10.8 1.8 2.0 1 0 0 1 1 1 0 Mechanosensitive ion channel An_peroxidase PF03098.15 EOO01297.1 - 8.4e-24 84.0 0.0 1.9e-23 82.9 0.0 1.5 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.22 EOO01297.1 - 0.038 12.7 0.1 0.25 10.1 0.0 1.9 2 0 0 2 2 2 0 Cytochrome P450 Methyltransf_3 PF01596.17 EOO01298.1 - 8.9e-13 47.9 0.0 1.2e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EOO01298.1 - 7.1e-10 39.9 0.0 1.2e-09 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DAO PF01266.24 EOO01299.1 - 2.7e-48 165.4 0.2 3e-48 165.2 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EOO01299.1 - 0.11 12.4 2.4 1 9.2 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.20 EOO01300.1 - 9.1e-14 51.7 0.0 1.6e-13 50.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EOO01300.1 - 1.4e-10 42.2 0.8 1.9e-10 41.7 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EOO01300.1 - 0.089 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 EOO01301.1 - 1.1e-35 123.2 25.1 1.6e-35 122.7 25.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EOO01301.1 - 6.5 6.4 14.7 0.023 14.4 4.5 2.2 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 Methyltransf_23 PF13489.6 EOO01302.1 - 3.9e-18 65.8 0.0 5.1e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO01302.1 - 7.2e-09 36.2 0.0 3.9e-08 33.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO01302.1 - 5e-07 29.6 0.0 0.0045 16.8 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EOO01302.1 - 7e-07 29.8 0.0 1.3e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO01302.1 - 1.1e-06 29.3 0.0 1.8e-05 25.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EOO01302.1 - 6.2e-05 22.4 0.0 0.79 9.0 0.0 3.1 2 1 0 2 2 2 2 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EOO01302.1 - 0.00017 21.8 0.0 0.00032 20.9 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EOO01302.1 - 0.0017 17.8 0.0 0.02 14.3 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EOO01302.1 - 0.0043 16.6 0.0 0.0097 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EOO01302.1 - 0.0088 15.5 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 EOO01302.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_16 PF10294.9 EOO01302.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase UPF0146 PF03686.13 EOO01302.1 - 0.13 12.1 0.0 8.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) adh_short PF00106.25 EOO01303.1 - 1.6e-34 119.1 0.1 2.2e-34 118.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO01303.1 - 7.9e-31 107.4 0.1 1.3e-30 106.7 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO01303.1 - 1.7e-10 41.1 0.2 2.9e-10 40.4 0.2 1.4 1 0 0 1 1 1 1 KR domain DUF1445 PF07286.12 EOO01304.1 - 8.9e-62 207.3 0.0 1.2e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) AA_permease PF00324.21 EOO01305.1 - 4.2e-111 371.9 37.1 5.1e-111 371.6 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EOO01305.1 - 3.2e-30 105.3 38.4 5.7e-30 104.5 38.4 1.3 1 1 0 1 1 1 1 Amino acid permease CSTF_C PF14304.6 EOO01306.1 - 3.4 7.3 7.3 0.17 11.5 1.7 1.8 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal DUF3435 PF11917.8 EOO01307.1 - 1.7e-23 83.3 10.1 8.8e-14 51.3 3.5 3.5 3 1 1 4 4 4 3 Protein of unknown function (DUF3435) TetR PF13972.6 EOO01307.1 - 0.037 13.7 0.4 0.079 12.7 0.4 1.5 1 0 0 1 1 1 0 Bacterial transcriptional repressor Abhydrolase_4 PF08386.10 EOO01308.1 - 4.3e-11 42.8 0.0 1.2e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 EOO01308.1 - 0.13 11.9 0.0 0.79 9.3 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold SNARE PF05739.19 EOO01311.1 - 6.6e-12 45.2 0.4 1.2e-11 44.4 0.4 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EOO01311.1 - 6.1e-05 22.8 1.8 6.1e-05 22.8 1.8 1.9 2 0 0 2 2 2 1 Syntaxin ODV-E18 PF10717.9 EOO01311.1 - 0.00092 19.0 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 Orf78 PF06024.12 EOO01311.1 - 0.0022 18.3 0.6 0.003 17.8 0.4 1.3 1 1 0 1 1 1 1 Orf78 (ac78) DUF5345 PF17280.2 EOO01311.1 - 0.028 14.4 0.4 0.085 12.8 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF2116 PF09889.9 EOO01311.1 - 0.031 14.2 1.0 0.031 14.2 1.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) ETRAMP PF09716.10 EOO01311.1 - 0.032 14.3 0.6 0.041 13.9 0.6 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF1218 PF06749.12 EOO01311.1 - 0.05 14.1 0.3 0.066 13.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) 7tm_7 PF08395.12 EOO01311.1 - 0.064 12.4 1.0 0.11 11.6 0.1 1.6 2 0 0 2 2 2 0 7tm Chemosensory receptor Phage_holin_3_6 PF07332.11 EOO01311.1 - 0.076 13.1 0.4 0.076 13.1 0.4 1.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III LAP1C PF05609.12 EOO01311.1 - 0.1 11.7 0.6 0.11 11.6 0.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Cytochrom_B559a PF00284.20 EOO01311.1 - 0.15 11.9 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit DUF4051 PF13260.6 EOO01311.1 - 0.52 10.1 2.6 1.2 8.9 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) EzrA PF06160.12 EOO01311.1 - 0.98 7.5 10.6 0.035 12.3 1.5 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA EMC3_TMCO1 PF01956.16 EOO01311.1 - 1.4 8.6 5.2 3.3 7.4 1.0 2.0 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like 4HB_MCP_1 PF12729.7 EOO01311.1 - 3.3 7.2 11.0 0.34 10.4 1.5 2.1 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction FAD_binding_4 PF01565.23 EOO01312.1 - 3.1e-10 39.9 1.5 3.1e-10 39.9 1.5 2.5 3 0 0 3 3 3 2 FAD binding domain A_deaminase PF00962.22 EOO01313.1 - 1e-14 54.6 0.0 6.1e-11 42.2 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase Glyco_hydro_28 PF00295.17 EOO01314.1 - 3.5e-05 23.0 11.5 0.0014 17.7 11.6 2.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_3_C PF01915.22 EOO01315.1 - 4.4e-55 186.8 0.0 1.1e-54 185.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EOO01315.1 - 5.6e-54 183.7 0.0 9.2e-54 183.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EOO01315.1 - 1.2e-19 70.2 0.3 6.6e-19 67.8 0.1 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF4232 PF14016.6 EOO01315.1 - 0.027 14.6 0.4 0.09 12.9 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) UDP-g_GGTase PF06427.11 EOO01316.1 - 0.22 11.6 0.1 0.42 10.8 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose:Glycoprotein Glucosyltransferase p450 PF00067.22 EOO01317.1 - 2.6e-52 178.1 0.0 3.8e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Transketolase_N PF00456.21 EOO01317.1 - 2.3e-14 53.1 0.6 6.8e-13 48.3 0.4 2.4 2 1 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.21 EOO01317.1 - 2.7e-05 24.0 0.2 0.00013 21.8 0.2 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 EOO01317.1 - 0.00011 21.2 0.0 0.00021 20.3 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Sugar_tr PF00083.24 EOO01318.1 - 7.4e-29 100.9 15.5 8.2e-29 100.8 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO01318.1 - 9.2e-05 21.5 15.5 0.00012 21.2 15.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3792 PF12670.7 EOO01318.1 - 8.4 6.6 17.5 3 8.0 8.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Aldo_ket_red PF00248.21 EOO01319.1 - 2.3e-31 109.1 0.0 2.7e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GFO_IDH_MocA PF01408.22 EOO01320.1 - 8.9e-18 65.3 0.1 1.4e-17 64.6 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EOO01320.1 - 0.1 13.3 0.0 0.17 12.6 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EOO01321.1 - 3.1e-07 31.2 0.0 6.5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EOO01321.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain MFS_1 PF07690.16 EOO01323.1 - 2.5e-42 145.1 47.5 8.7e-37 126.8 30.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EOO01323.1 - 6.6 5.9 23.8 4.6e+02 -0.1 23.8 2.2 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Transketolase_C PF02780.20 EOO01325.1 - 1.5e-14 53.9 0.0 2e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EOO01325.1 - 0.039 14.3 0.0 0.067 13.5 0.0 1.4 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II MFS_1 PF07690.16 EOO01326.1 - 3.6e-13 49.2 4.8 3.9e-13 49.0 4.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO01326.1 - 2.7e-06 26.5 1.0 2.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter adh_short_C2 PF13561.6 EOO01327.1 - 2.4e-13 50.2 0.7 3.2e-13 49.8 0.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO01327.1 - 3.1e-13 49.6 0.1 4.4e-13 49.1 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EOO01327.1 - 0.00037 19.7 0.2 0.00057 19.1 0.2 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EOO01327.1 - 0.0015 18.0 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 EOO01327.1 - 0.035 13.5 0.0 0.076 12.4 0.0 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EOO01327.1 - 0.08 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Hydrolase_4 PF12146.8 EOO01328.1 - 4.4e-12 45.8 0.1 2.8e-11 43.2 0.0 2.0 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EOO01328.1 - 1.2e-10 41.5 0.1 2e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EOO01328.1 - 7.4e-10 39.8 3.2 1.3e-09 39.0 3.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Polysacc_deac_1 PF01522.21 EOO01329.1 - 0.00018 21.4 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase AA_permease_2 PF13520.6 EOO01330.1 - 2.1e-65 221.2 42.4 2.9e-65 220.8 42.4 1.2 1 0 0 1 1 1 1 Amino acid permease MCU PF04678.13 EOO01330.1 - 6.3e-25 88.3 0.1 6.3e-25 88.3 0.1 2.6 3 0 0 3 3 3 1 Mitochondrial calcium uniporter AA_permease PF00324.21 EOO01330.1 - 9e-16 57.5 32.5 1.3e-15 57.0 32.5 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1281 PF06924.11 EOO01330.1 - 0.086 12.4 0.2 0.17 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) Myb_DNA-bind_3 PF12776.7 EOO01331.1 - 1.8e-25 89.7 0.2 2.3e-25 89.4 0.2 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SPATA48 PF15073.6 EOO01332.1 - 0.1 12.9 1.8 0.13 12.6 0.2 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated protein 48 Folliculin PF11704.8 EOO01332.1 - 0.57 10.1 3.0 2.1 8.2 2.7 2.0 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport APH PF01636.23 EOO01333.1 - 7.7e-12 45.6 0.3 1.2e-11 45.0 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2336 PF10098.9 EOO01333.1 - 0.0065 16.0 0.8 0.0096 15.4 0.8 1.2 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2336) DUF2388 PF09498.10 EOO01333.1 - 0.058 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) RIO1 PF01163.22 EOO01333.1 - 0.096 12.3 0.1 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.20 EOO01333.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase CdiA_C_tRNase PF18664.1 EOO01333.1 - 0.18 12.0 0.0 0.44 10.8 0.0 1.6 1 1 0 1 1 1 0 CdiA C-terminal tRNase domain DehI PF10778.9 EOO01333.1 - 0.2 11.8 0.0 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 Halocarboxylic acid dehydrogenase DehI tRNA_Me_trans PF03054.16 EOO01336.1 - 0.21 10.4 0.3 0.3 9.8 0.3 1.2 1 0 0 1 1 1 0 tRNA methyl transferase TP2 PF01254.18 EOO01336.1 - 6 7.5 14.0 7.3 7.2 5.6 2.6 2 0 0 2 2 2 0 Nuclear transition protein 2 PBP1_TM PF14812.6 EOO01337.1 - 0.13 12.6 0.6 0.35 11.3 0.6 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2258 PF10015.9 EOO01337.1 - 0.22 11.7 0.0 0.48 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) Sugar_tr PF00083.24 EOO01339.1 - 2.3e-55 188.3 9.9 2.6e-55 188.1 9.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO01339.1 - 0.0017 17.3 21.1 0.0022 17.0 20.2 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3624 PF12292.8 EOO01339.1 - 0.011 16.1 1.4 3.6 8.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) Alpha-L-AF_C PF06964.12 EOO01340.1 - 1.1e-29 103.7 0.0 1.7e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain RVT_1 PF00078.27 EOO01341.1 - 8.7e-12 45.0 0.0 1.1e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BEN PF10523.9 EOO01341.1 - 0.19 12.0 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 BEN domain APG6_N PF17675.1 EOO01342.1 - 0.021 15.3 0.1 0.058 13.9 0.1 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region LEA_3 PF03242.13 EOO01342.1 - 0.11 13.3 0.8 0.29 11.9 0.8 1.7 1 0 0 1 1 1 0 Late embryogenesis abundant protein Sugar_tr PF00083.24 EOO01343.1 - 4.4e-60 203.8 17.3 5e-60 203.6 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO01343.1 - 9e-08 31.4 11.5 1.1e-07 31.1 11.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MATalpha_HMGbox PF04769.12 EOO01344.1 - 7e-37 126.7 0.0 1e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box MAT1-1-2 PF17043.5 EOO01345.1 - 8.9e-37 126.3 0.0 1.5e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 Mating type protein 1-1-2 of unknown function DUF2400 PF09674.10 EOO01345.1 - 0.11 12.4 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Exo_endo_phos PF03372.23 EOO01346.1 - 9.4e-15 54.8 0.0 1.3e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family COX6A PF02046.15 EOO01347.1 - 9.7e-42 142.0 2.8 2.1e-41 140.9 2.8 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF2933 PF11666.8 EOO01347.1 - 0.0093 16.0 0.1 0.018 15.1 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2933) HMG_box PF00505.19 EOO01348.1 - 1.2e-10 41.6 0.1 1.9e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box Ccdc124 PF06244.12 EOO01348.1 - 0.019 15.5 0.0 0.02 15.4 0.0 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 Macscav_rec PF03523.13 EOO01348.1 - 0.052 13.4 1.2 1.4 8.8 0.0 2.7 2 1 0 2 2 2 0 Macrophage scavenger receptor HMG_box_2 PF09011.10 EOO01348.1 - 0.092 13.4 0.1 0.14 12.8 0.1 1.3 1 0 0 1 1 1 0 HMG-box domain DUF5074 PF16819.5 EOO01348.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5074) Glyco_transf_28 PF03033.20 EOO01349.1 - 6.3e-17 61.9 0.1 4.4e-16 59.2 0.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EOO01349.1 - 3.4e-05 22.8 0.0 5.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 EOO01349.1 - 0.035 14.5 0.0 0.25 11.7 0.0 2.4 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 EOO01349.1 - 0.037 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain YjcZ PF13990.6 EOO01350.1 - 0.04 13.3 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 YjcZ-like protein Oest_recep PF02159.15 EOO01350.1 - 1.6 9.2 6.4 11 6.5 4.5 2.2 1 1 1 2 2 2 0 Oestrogen receptor Kinetochor_Ybp2 PF08568.10 EOO01351.1 - 2e-33 115.8 0.1 2.2e-33 115.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin DUF2777 PF10949.8 EOO01351.1 - 0.75 9.4 2.6 7.7 6.1 0.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2777) NTase_sub_bind PF08780.11 EOO01352.1 - 0.069 13.1 0.3 0.17 11.9 0.3 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like PAN_4 PF14295.6 EOO01353.1 - 9.2e-05 22.3 0.4 0.00015 21.6 0.4 1.4 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 EOO01353.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 PAN domain Zip PF02535.22 EOO01353.1 - 0.025 13.8 0.0 0.033 13.4 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PAN_2 PF08276.11 EOO01353.1 - 0.037 14.2 1.0 0.075 13.2 1.0 1.4 1 0 0 1 1 1 0 PAN-like domain PAN_3 PF08277.12 EOO01353.1 - 0.083 12.7 0.5 0.15 11.9 0.5 1.3 1 0 0 1 1 1 0 PAN-like domain Isochorismatase PF00857.20 EOO01354.1 - 2.1e-14 54.1 0.0 4e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family Topoisom_bac PF01131.20 EOO01355.1 - 5.4e-107 358.3 0.0 8.9e-101 337.9 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 EOO01355.1 - 5.5e-12 45.8 0.0 1.3e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Toprim domain RdRP_1 PF00680.20 EOO01355.1 - 0.095 11.2 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase PRR20 PF15708.5 EOO01355.1 - 0.7 9.8 5.8 1.3 8.9 5.8 1.3 1 0 0 1 1 1 0 Proline-rich protein family 20 PI3_PI4_kinase PF00454.27 EOO01356.1 - 6.5e-46 157.2 0.0 8.8e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EOO01356.1 - 5.4e-11 42.1 0.0 9.3e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 FATC domain Cullin PF00888.22 EOO01357.1 - 3.7e-184 613.8 0.7 4.6e-184 613.5 0.7 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EOO01357.1 - 2.5e-26 91.5 0.3 7e-26 90.0 0.3 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_IclR PF09339.10 EOO01357.1 - 0.031 14.1 0.0 0.091 12.6 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR_2 PF12802.7 EOO01357.1 - 0.1 12.5 0.0 12 5.9 0.0 3.1 3 0 0 3 3 3 0 MarR family HTH_20 PF12840.7 EOO01357.1 - 0.13 12.3 0.0 29 4.8 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain adh_short PF00106.25 EOO01358.1 - 5.6e-24 84.7 0.0 1.2e-19 70.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EOO01358.1 - 3.2e-17 62.9 0.0 2.5e-13 50.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO01358.1 - 9e-08 32.2 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO01358.1 - 0.00043 19.8 0.0 0.00063 19.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TIR-like PF10137.9 EOO01358.1 - 0.049 13.6 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain COesterase PF00135.28 EOO01359.1 - 1.7e-72 245.0 0.1 4.3e-68 230.4 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EOO01359.1 - 1.8e-08 34.5 0.9 1.6e-07 31.4 0.8 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EOO01359.1 - 0.12 11.9 0.2 0.2 11.1 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Amidase PF01425.21 EOO01360.1 - 2.8e-51 174.9 0.1 3.8e-51 174.5 0.1 1.1 1 0 0 1 1 1 1 Amidase Melibiase_2 PF16499.5 EOO01360.1 - 0.021 14.0 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Alpha galactosidase A PHM7_ext PF12621.8 EOO01360.1 - 0.082 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter Nup192 PF11894.8 EOO01361.1 - 1.9e-128 429.8 0.1 2.1e-128 429.7 0.1 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF2243 PF10002.9 EOO01361.1 - 0.23 11.6 2.2 28 4.8 0.0 2.9 2 1 1 3 3 3 0 Predicted membrane protein (DUF2243) VCBS PF13517.6 EOO01362.1 - 2.1e-32 111.5 59.1 2.6e-10 40.8 5.0 9.0 4 2 5 9 9 9 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 EOO01362.1 - 0.0014 18.1 6.8 13 5.1 0.0 5.9 6 1 1 7 7 7 2 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 EOO01362.1 - 0.0054 16.8 34.2 0.15 12.2 0.9 6.8 5 0 0 5 5 5 4 FG-GAP repeat CBM_11 PF03425.13 EOO01362.1 - 0.0092 15.9 0.7 0.021 14.7 0.7 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) Stb3 PF10330.9 EOO01363.1 - 2e-39 133.5 0.0 3.2e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein DUF3602 PF12223.8 EOO01364.1 - 1.6e-09 38.2 15.0 0.0032 18.0 0.9 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DUF4719 PF15843.5 EOO01364.1 - 0.18 11.9 4.8 0.25 11.4 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) DUF1180 PF06679.12 EOO01364.1 - 0.29 11.5 4.2 0.43 11.0 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Ku_PK_bind PF08785.11 EOO01367.1 - 8e-36 122.8 0.0 1.6e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 EOO01367.1 - 5.4e-31 107.9 0.0 9.3e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EOO01367.1 - 1.4e-17 64.2 0.1 2.4e-17 63.4 0.1 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 EOO01367.1 - 3.6e-05 24.1 0.1 0.00011 22.5 0.1 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain CH PF00307.31 EOO01369.1 - 5.9e-13 49.0 0.0 9.3e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EOO01369.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain DNApol_Exo PF18136.1 EOO01370.1 - 1.5e-104 349.2 0.0 2.6e-104 348.3 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EOO01370.1 - 3.4e-53 181.1 0.0 1e-52 179.5 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family A Pam16 PF03656.13 EOO01371.1 - 4.9e-07 29.8 0.0 5.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 EOO01371.1 - 4.3e-05 23.5 0.0 6.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Oxidored_FMN PF00724.20 EOO01373.1 - 1.3e-84 284.5 0.0 1.4e-84 284.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 EOO01373.1 - 0.0016 17.9 0.1 0.0027 17.2 0.1 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Sugar_tr PF00083.24 EOO01375.1 - 1.4e-53 182.4 10.5 1.8e-53 182.0 10.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO01375.1 - 5.3e-06 25.6 17.2 5.3e-06 25.6 17.2 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Atu4866 PF11512.8 EOO01375.1 - 0.052 13.9 0.1 0.53 10.7 0.0 2.2 2 0 0 2 2 2 0 Agrobacterium tumefaciens protein Atu4866 DUF4131 PF13567.6 EOO01375.1 - 0.85 9.3 10.6 2.7 7.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) AtuA PF07287.11 EOO01376.1 - 6.2e-109 363.9 0.1 8.6e-109 363.5 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA AMP-binding PF00501.28 EOO01377.1 - 5.4e-88 295.4 0.0 6.8e-88 295.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EOO01377.1 - 1.1e-08 36.0 0.0 2.5e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ank_2 PF12796.7 EOO01378.1 - 4.3e-37 126.6 0.2 9.4e-14 51.8 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EOO01378.1 - 1.7e-30 105.0 0.3 5e-09 36.5 0.0 4.3 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EOO01378.1 - 1.6e-21 74.1 0.0 0.015 15.8 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EOO01378.1 - 2.7e-18 65.8 2.1 7.7e-06 26.1 0.0 5.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EOO01378.1 - 3.7e-18 65.1 0.1 0.006 17.0 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat PNP_UDP_1 PF01048.20 EOO01378.1 - 1.4e-12 47.3 1.3 8.2e-12 44.9 1.3 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily Sugar_tr PF00083.24 EOO01379.1 - 9.3e-102 341.2 23.7 1.1e-101 341.0 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO01379.1 - 1.1e-25 90.4 24.0 1.1e-25 90.4 24.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EOO01379.1 - 0.00031 19.2 18.0 0.064 11.5 2.8 3.8 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Neuro_bHLH PF12533.8 EOO01379.1 - 0.17 13.1 0.0 0.32 12.2 0.0 1.3 1 0 0 1 1 1 0 Neuronal helix-loop-helix transcription factor Aldo_ket_red PF00248.21 EOO01380.1 - 1.9e-23 83.1 0.4 1.9e-10 40.4 0.0 3.0 1 1 2 3 3 3 3 Aldo/keto reductase family T3SS_ExsE PF18286.1 EOO01380.1 - 0.11 12.4 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Type III secretion system ExsE Aldedh PF00171.22 EOO01381.1 - 2.8e-122 408.5 0.5 3.2e-122 408.4 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EOO01381.1 - 0.19 11.2 0.0 1.3 8.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) NACHT PF05729.12 EOO01382.1 - 4e-09 36.6 0.5 2.9e-08 33.8 0.1 2.5 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EOO01382.1 - 4.8e-08 33.6 0.6 2.1e-07 31.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EOO01382.1 - 6.1e-05 23.3 0.0 0.00021 21.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain ThiP_synth PF10120.9 EOO01382.1 - 0.078 12.6 0.1 4.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Thiamine-phosphate synthase NUC130_3NT PF08158.12 EOO01382.1 - 0.14 12.5 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 NUC130/3NT domain Peptidase_M19 PF01244.21 EOO01383.1 - 3.3e-46 157.9 0.0 4.3e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) CBP_BcsG PF11658.8 EOO01383.1 - 0.16 10.3 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Pkinase PF00069.25 EOO01384.1 - 1.5e-70 237.6 0.0 1.9e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO01384.1 - 1.1e-32 113.4 0.0 2.7e-32 112.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EOO01384.1 - 1.7e-05 24.3 0.0 0.00016 21.1 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EOO01384.1 - 0.0018 17.3 0.3 0.0046 15.9 0.3 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EOO01384.1 - 0.012 15.0 0.4 0.033 13.6 0.4 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EOO01384.1 - 0.022 14.7 0.1 0.022 14.7 0.1 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EOO01384.1 - 0.053 12.6 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EOO01384.1 - 0.066 12.0 0.1 0.066 12.0 0.1 1.5 2 0 0 2 2 2 0 Fungal protein kinase Sugar_tr PF00083.24 EOO01385.1 - 9.1e-25 87.4 11.9 1e-24 87.2 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DAO PF01266.24 EOO01388.1 - 1.6e-38 133.2 0.0 1.9e-38 133.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EOO01388.1 - 0.003 17.6 0.0 0.019 14.9 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EOO01388.1 - 0.008 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EOO01388.1 - 0.019 15.2 0.0 0.061 13.6 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EOO01388.1 - 0.042 13.1 0.0 2.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EOO01388.1 - 0.12 12.9 0.1 2.1 8.9 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Alpha_L_fucos PF01120.17 EOO01389.1 - 4.5e-69 233.6 0.2 5.6e-69 233.2 0.2 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 EOO01389.1 - 0.0089 16.6 0.0 0.02 15.4 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain GHL6 PF14871.6 EOO01389.1 - 0.013 15.6 0.0 0.037 14.2 0.0 1.8 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 PseudoU_synth_1 PF01416.20 EOO01390.1 - 4.2e-12 46.5 0.0 1e-10 42.0 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase Hydantoinase_B PF02538.14 EOO01391.1 - 1.6e-144 482.2 2.1 1.4e-122 409.7 0.0 2.7 2 1 1 3 3 3 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EOO01391.1 - 4.8e-93 311.6 0.3 6.2e-91 304.7 0.1 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EOO01391.1 - 2.5e-43 147.9 1.6 5.9e-42 143.4 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Peptidase_C12 PF01088.21 EOO01392.1 - 6.9e-13 48.8 0.0 8.2e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 YvfG PF09628.10 EOO01392.1 - 0.13 12.6 0.0 0.47 10.8 0.0 1.8 2 0 0 2 2 2 0 YvfG protein Med22 PF06179.12 EOO01393.1 - 8e-24 83.9 0.8 9.8e-24 83.6 0.8 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Peptidase_S28 PF05577.12 EOO01393.1 - 0.062 12.1 0.0 0.11 11.3 0.0 1.3 2 0 0 2 2 2 0 Serine carboxypeptidase S28 Pkinase PF00069.25 EOO01394.1 - 8.2e-68 228.6 0.0 1.1e-67 228.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO01394.1 - 5.3e-31 107.8 0.0 6.8e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EOO01394.1 - 0.0014 17.7 0.0 0.016 14.2 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EOO01394.1 - 0.0027 17.7 0.0 0.0074 16.2 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EOO01394.1 - 0.0064 15.9 0.0 0.011 15.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EOO01394.1 - 0.019 14.1 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EOO01394.1 - 0.077 12.3 0.0 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family D5_N PF08706.11 EOO01395.1 - 0.18 12.1 0.3 0.71 10.1 0.0 2.1 2 0 0 2 2 2 0 D5 N terminal like MFS_1 PF07690.16 EOO01396.1 - 6.7e-26 91.1 18.9 8.8e-26 90.7 18.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EOO01396.1 - 0.00014 21.3 1.0 0.00014 21.3 1.0 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB NicO PF03824.16 EOO01397.1 - 4.9e-47 160.6 0.6 7.1e-47 160.1 0.0 1.5 1 1 0 1 1 1 1 High-affinity nickel-transport protein Peptidase_C2 PF00648.21 EOO01398.1 - 2.4e-59 200.8 1.2 5e-58 196.5 1.2 2.2 1 1 0 1 1 1 1 Calpain family cysteine protease DUF1681 PF07933.14 EOO01400.1 - 7.2e-60 201.0 0.0 9.9e-60 200.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Aminotran_1_2 PF00155.21 EOO01401.1 - 4.3e-08 32.7 0.0 2.6e-07 30.1 0.0 2.2 2 1 0 2 2 2 1 Aminotransferase class I and II Tannase PF07519.11 EOO01401.1 - 0.11 11.4 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase ETF PF01012.21 EOO01402.1 - 3.6e-44 150.8 0.5 4.3e-44 150.6 0.5 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain RRM_1 PF00076.22 EOO01403.1 - 4.2e-32 109.8 0.0 2.1e-15 56.3 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EOO01403.1 - 0.00013 22.0 0.0 0.079 13.1 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 EOO01403.1 - 0.00018 21.1 0.0 0.37 10.4 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 EOO01403.1 - 0.011 15.6 0.2 6.4 6.9 0.1 3.2 3 0 0 3 3 3 0 DbpA RNA binding domain PHM7_cyt PF14703.6 EOO01403.1 - 0.018 15.3 0.0 8.9 6.5 0.0 3.2 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF4944 PF16302.5 EOO01403.1 - 0.034 14.2 0.0 6.6 6.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4944) DUF4783 PF16022.5 EOO01403.1 - 0.035 14.3 0.0 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) Limkain-b1 PF11608.8 EOO01403.1 - 0.069 13.2 0.5 12 6.0 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 Importin_rep_5 PF18816.1 EOO01403.1 - 0.1 12.9 0.2 0.21 11.9 0.2 1.5 1 0 0 1 1 1 0 Importin repeat DUF5549 PF17703.1 EOO01403.1 - 2.9 7.5 8.8 5.9 6.5 8.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5549) Rhomboid PF01694.22 EOO01404.1 - 1.4e-32 112.8 7.3 1.4e-32 112.8 7.3 1.9 2 0 0 2 2 2 1 Rhomboid family DUF4381 PF14316.6 EOO01404.1 - 0.49 10.6 1.9 1 9.6 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ABC2_membrane_5 PF13346.6 EOO01404.1 - 5 6.6 9.8 12 5.3 3.2 3.0 3 0 0 3 3 3 0 ABC-2 family transporter protein Carn_acyltransf PF00755.20 EOO01405.1 - 5.8e-208 692.2 0.0 6.6e-208 692.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase WD40 PF00400.32 EOO01407.1 - 1.3e-22 79.7 3.3 6.4e-05 23.7 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 EOO01407.1 - 4.7e-05 22.2 4.1 0.91 8.1 0.1 4.0 2 2 2 4 4 4 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EOO01407.1 - 0.00094 19.4 0.0 2.7 8.4 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EOO01407.1 - 0.071 13.1 0.0 2.5 8.2 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region MARVEL PF01284.23 EOO01408.1 - 7.9e-05 22.7 19.7 0.00011 22.2 19.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4233 PF14017.6 EOO01408.1 - 7 7.0 12.6 1.1 9.7 7.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) Malic_M PF03949.15 EOO01409.1 - 2.6e-95 318.6 0.0 3.4e-95 318.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EOO01409.1 - 2.9e-70 235.8 0.0 5.7e-70 234.8 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Rep_fac_C PF08542.11 EOO01410.1 - 3.4e-23 81.8 0.0 8.8e-23 80.5 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EOO01410.1 - 6.3e-13 48.8 0.0 2e-09 37.4 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EOO01410.1 - 2.9e-12 47.1 0.0 5.1e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EOO01410.1 - 7.6e-07 29.2 0.0 1.9e-06 27.9 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EOO01410.1 - 2.1e-06 28.2 0.0 0.00017 22.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EOO01410.1 - 7.5e-05 22.5 0.0 0.00019 21.2 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 EOO01410.1 - 9.8e-05 22.2 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EOO01410.1 - 0.00014 22.1 0.1 0.16 12.3 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_3 PF07726.11 EOO01410.1 - 0.00023 21.0 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 EOO01410.1 - 0.0026 17.6 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 EOO01410.1 - 0.0026 17.2 0.0 0.035 13.5 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EOO01410.1 - 0.0026 17.8 0.0 0.0099 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EOO01410.1 - 0.0027 17.7 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain MeaB PF03308.16 EOO01410.1 - 0.0055 15.7 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_assoc_2 PF16193.5 EOO01410.1 - 0.0069 16.7 0.0 0.023 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_gamma3 PF12169.8 EOO01410.1 - 0.0072 16.2 0.3 0.53 10.2 0.0 3.2 3 0 0 3 3 3 1 DNA polymerase III subunits gamma and tau domain III TniB PF05621.11 EOO01410.1 - 0.0087 15.5 0.0 3 7.2 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein KTI12 PF08433.10 EOO01410.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_11 PF13086.6 EOO01410.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EOO01410.1 - 0.017 15.0 0.2 0.064 13.2 0.1 2.0 1 1 1 2 2 2 0 NTPase AAA_24 PF13479.6 EOO01410.1 - 0.018 14.8 0.0 0.044 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 EOO01410.1 - 0.021 14.6 0.1 0.5 10.1 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.6 EOO01410.1 - 0.036 14.4 0.1 0.11 12.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain MipZ PF09140.11 EOO01410.1 - 0.11 11.7 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 ATPase MipZ AAA_30 PF13604.6 EOO01410.1 - 0.14 11.8 0.1 0.46 10.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EOO01410.1 - 0.16 12.3 0.1 0.62 10.5 0.1 2.0 1 1 0 1 1 1 0 RNA helicase Flg_bb_rod PF00460.20 EOO01410.1 - 3.2 7.8 5.1 42 4.2 1.8 2.6 2 0 0 2 2 2 0 Flagella basal body rod protein Sacchrp_dh_C PF16653.5 EOO01411.1 - 1.9e-92 310.2 0.0 2.6e-92 309.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EOO01411.1 - 9e-26 90.7 0.7 1.3e-25 90.1 0.7 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EOO01411.1 - 9.8e-05 22.4 0.1 0.00019 21.5 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EOO01411.1 - 0.0011 18.9 0.3 0.002 18.1 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H-binding IlvN PF07991.12 EOO01411.1 - 0.0015 18.1 1.3 0.016 14.8 0.4 2.5 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_3 PF03447.16 EOO01411.1 - 0.0099 16.5 0.4 0.018 15.7 0.4 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EOO01411.1 - 0.023 14.0 0.2 0.037 13.3 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 EOO01411.1 - 0.081 13.7 0.1 0.15 12.9 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.16 EOO01412.1 - 4.9 6.0 21.6 32 3.3 21.6 2.1 1 1 0 1 1 1 0 Major Facilitator Superfamily Kelch_5 PF13854.6 EOO01413.1 - 3.3e-08 33.3 6.5 3.7e-08 33.2 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 EOO01413.1 - 0.00096 19.1 3.6 0.4 10.7 0.5 3.5 3 1 0 3 3 3 2 Galactose oxidase, central domain SKG6 PF08693.10 EOO01413.1 - 0.0082 15.5 0.6 0.019 14.4 0.6 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CD99L2 PF12301.8 EOO01413.1 - 0.16 12.3 0.2 0.27 11.5 0.2 1.4 1 0 0 1 1 1 0 CD99 antigen like protein 2 Kelch_6 PF13964.6 EOO01413.1 - 0.21 11.9 3.7 29 5.1 0.0 4.0 4 0 0 4 4 4 0 Kelch motif TDA11 PF17084.5 EOO01413.1 - 0.34 9.8 4.1 0.49 9.3 4.1 1.2 1 0 0 1 1 1 0 Topoisomerase I damage affected protein 11 Questin_oxidase PF14027.6 EOO01414.1 - 2.1e-87 293.8 2.5 6e-85 285.8 2.5 2.1 1 1 0 1 1 1 1 Questin oxidase-like WSC PF01822.19 EOO01415.1 - 4.8e-53 177.3 49.1 1.2e-19 70.2 9.0 3.9 4 0 0 4 4 4 3 WSC domain peroxidase PF00141.23 EOO01415.1 - 6.6e-25 88.1 0.0 1.2e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Acetyltransf_1 PF00583.25 EOO01416.1 - 5.5e-05 23.4 0.0 9.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Cpn10 PF00166.21 EOO01417.1 - 1.6e-28 98.6 0.0 1.8e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Exo70 PF03081.15 EOO01418.1 - 4.4e-92 309.0 0.0 1.3e-91 307.5 0.0 1.8 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Baculo_PEP_C PF04513.12 EOO01418.1 - 0.016 15.3 6.0 5.3 7.1 0.1 3.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MukF_M PF17192.4 EOO01418.1 - 0.066 13.0 3.2 3.3 7.4 0.0 3.0 3 1 0 3 3 3 0 MukF middle domain Apolipoprotein PF01442.18 EOO01418.1 - 0.13 12.1 7.0 0.23 11.3 0.1 3.3 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain GAS PF13851.6 EOO01418.1 - 0.32 10.3 10.9 1.9 7.8 0.2 4.1 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding DUF2203 PF09969.9 EOO01418.1 - 0.38 11.5 3.5 0.61 10.8 0.2 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) BCIP PF13862.6 EOO01419.1 - 8.4e-70 234.7 0.1 1.1e-69 234.4 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Csm1 PF12539.8 EOO01420.1 - 1.2e-33 115.6 0.0 3.8e-33 114.0 0.0 1.8 2 0 0 2 2 1 1 Chromosome segregation protein Csm1/Pcs1 ERM PF00769.19 EOO01420.1 - 0.00059 19.7 7.1 0.00062 19.7 7.1 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family PspA_IM30 PF04012.12 EOO01420.1 - 0.0015 18.2 9.1 0.0015 18.2 9.1 2.5 2 1 1 3 3 2 1 PspA/IM30 family Phlebovirus_NSM PF07246.11 EOO01420.1 - 0.0017 17.8 5.4 0.0022 17.4 5.4 1.1 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M ABC_tran_CTD PF16326.5 EOO01420.1 - 0.0026 18.0 3.4 0.0026 18.0 3.4 2.5 1 1 1 2 2 2 1 ABC transporter C-terminal domain BBP1_C PF15272.6 EOO01420.1 - 0.0082 16.0 4.2 0.011 15.6 4.2 1.2 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal Lipoprotein_20 PF13942.6 EOO01420.1 - 0.01 15.8 3.1 0.015 15.2 3.1 1.3 1 0 0 1 1 1 1 YfhG lipoprotein Golgin_A5 PF09787.9 EOO01420.1 - 0.016 14.7 3.8 0.022 14.2 3.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 EzrA PF06160.12 EOO01420.1 - 0.018 13.2 6.2 0.029 12.6 6.2 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA BAR_3 PF16746.5 EOO01420.1 - 0.019 14.7 4.3 0.03 14.0 4.3 1.2 1 0 0 1 1 1 0 BAR domain of APPL family Snf7 PF03357.21 EOO01420.1 - 0.021 14.4 9.3 0.033 13.8 9.3 1.2 1 0 0 1 1 1 0 Snf7 Exonuc_VII_L PF02601.15 EOO01420.1 - 0.024 14.2 5.6 0.031 13.9 5.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FmiP_Thoc5 PF09766.9 EOO01420.1 - 0.026 13.8 5.6 0.04 13.2 5.6 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 TMF_DNA_bd PF12329.8 EOO01420.1 - 0.031 14.3 4.4 0.031 14.3 4.4 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.19 EOO01420.1 - 0.04 11.9 2.6 0.047 11.6 2.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MCC-bdg_PDZ PF10506.9 EOO01420.1 - 0.044 13.8 3.7 0.55 10.3 0.7 2.5 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome FAM76 PF16046.5 EOO01420.1 - 0.059 12.7 4.4 0.077 12.3 4.4 1.2 1 0 0 1 1 1 0 FAM76 protein Rootletin PF15035.6 EOO01420.1 - 0.09 12.8 9.2 0.13 12.2 9.2 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Spc7 PF08317.11 EOO01420.1 - 0.1 11.5 11.5 0.046 12.6 9.7 1.4 2 0 0 2 2 1 0 Spc7 kinetochore protein AATF-Che1 PF13339.6 EOO01420.1 - 0.12 13.1 4.6 0.2 12.4 4.6 1.4 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor TACC_C PF05010.14 EOO01420.1 - 0.13 12.1 10.7 0.16 11.7 5.5 2.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FapA PF03961.13 EOO01420.1 - 0.15 10.6 3.7 0.19 10.3 3.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prominin PF05478.11 EOO01420.1 - 0.17 9.8 0.9 0.2 9.6 0.9 1.1 1 0 0 1 1 1 0 Prominin AAA_13 PF13166.6 EOO01420.1 - 0.17 10.5 9.6 0.23 10.0 9.6 1.1 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.12 EOO01420.1 - 0.2 11.7 20.3 0.029 14.4 16.1 1.7 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein DWNN PF08783.11 EOO01420.1 - 0.2 12.0 1.2 15 5.9 0.0 3.1 2 1 1 3 3 3 0 DWNN domain YvrJ PF12841.7 EOO01420.1 - 0.21 11.2 0.1 0.52 9.9 0.1 1.7 1 0 0 1 1 1 0 YvrJ protein family Allexi_40kDa PF05549.11 EOO01420.1 - 0.22 11.0 1.1 0.3 10.5 1.1 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein ADIP PF11559.8 EOO01420.1 - 0.23 11.5 10.9 0.44 10.6 10.5 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fmp27_WPPW PF10359.9 EOO01420.1 - 0.25 10.2 5.4 0.3 9.9 5.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Atg14 PF10186.9 EOO01420.1 - 0.25 10.4 7.1 0.35 9.9 7.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 XhlA PF10779.9 EOO01420.1 - 0.26 11.5 0.3 0.26 11.5 0.3 2.4 2 0 0 2 2 2 0 Haemolysin XhlA USP8_interact PF08941.10 EOO01420.1 - 0.26 11.1 1.9 0.31 10.8 0.5 1.7 1 1 1 2 2 2 0 USP8 interacting Seryl_tRNA_N PF02403.22 EOO01420.1 - 0.3 11.3 13.5 0.31 11.3 7.5 2.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Dor1 PF04124.12 EOO01420.1 - 0.32 9.6 5.8 0.45 9.2 5.8 1.2 1 0 0 1 1 1 0 Dor1-like family Fib_alpha PF08702.10 EOO01420.1 - 0.39 10.9 4.3 0.69 10.1 4.3 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF5094 PF17015.5 EOO01420.1 - 0.4 10.8 4.7 1.4 9.0 0.0 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF5094) Nup88 PF10168.9 EOO01420.1 - 0.52 8.0 8.7 0.68 7.7 8.7 1.1 1 0 0 1 1 1 0 Nuclear pore component SHE3 PF17078.5 EOO01420.1 - 0.52 10.0 7.9 4.3 7.0 0.6 2.3 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 UPF0242 PF06785.11 EOO01420.1 - 0.55 10.3 8.5 0.9 9.6 8.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3138 PF11336.8 EOO01420.1 - 0.55 8.8 5.2 0.74 8.4 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF724 PF05266.14 EOO01420.1 - 0.64 9.8 7.4 0.98 9.2 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CLZ PF16526.5 EOO01420.1 - 0.94 9.9 5.7 0.58 10.6 2.4 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GAS PF13851.6 EOO01420.1 - 0.95 8.8 11.8 0.17 11.2 4.1 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF16 PF01519.16 EOO01420.1 - 1.3 9.5 5.2 1.5 9.3 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF2203 PF09969.9 EOO01420.1 - 1.4 9.7 6.4 2.7 8.7 6.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Cob_adeno_trans PF01923.18 EOO01420.1 - 1.6 8.8 5.6 7.8 6.6 5.5 1.9 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Fzo_mitofusin PF04799.13 EOO01420.1 - 1.7 8.2 5.8 7.7 6.0 5.5 1.8 1 1 0 1 1 1 0 fzo-like conserved region CHDCT2 PF08074.11 EOO01420.1 - 1.7 8.8 4.5 3.2 7.9 3.7 1.7 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain DUF4407 PF14362.6 EOO01420.1 - 2.5 7.4 13.6 2.8 7.2 12.4 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) SlyX PF04102.12 EOO01420.1 - 2.6 8.7 5.2 3.9 8.2 0.3 3.0 1 1 0 2 2 2 0 SlyX TMPIT PF07851.13 EOO01420.1 - 3.3 6.9 6.7 5.6 6.1 6.7 1.4 1 1 0 1 1 1 0 TMPIT-like protein KxDL PF10241.9 EOO01420.1 - 3.7 7.9 7.9 4.1 7.8 1.7 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein YabA PF06156.13 EOO01420.1 - 5.1 7.8 6.5 2.2 8.9 1.4 2.3 1 1 2 3 3 3 0 Initiation control protein YabA Spc24 PF08286.11 EOO01420.1 - 6.5 7.1 9.1 1.2 9.4 1.8 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 OmpH PF03938.14 EOO01420.1 - 7 7.0 17.2 0.45 10.8 8.5 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Cupin_1 PF00190.22 EOO01421.1 - 5e-17 61.9 0.2 8.7e-17 61.1 0.2 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 EOO01421.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.6 1 1 0 1 1 1 0 Cupin domain PfkB PF00294.24 EOO01422.1 - 6.9e-15 55.1 0.1 3e-09 36.6 0.4 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase LCM PF04072.14 EOO01423.1 - 1.9e-25 89.9 0.1 4.4e-25 88.7 0.0 1.6 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase DUF572 PF04502.13 EOO01424.1 - 7.3e-72 242.8 9.4 8.6e-72 242.5 9.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.13 EOO01424.1 - 0.027 14.4 0.8 0.05 13.5 0.8 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) zf-ACC PF17848.1 EOO01424.1 - 0.079 13.1 2.9 0.46 10.6 0.5 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zinc_ribbon_12 PF11331.8 EOO01424.1 - 0.44 10.4 1.5 14 5.6 1.5 2.4 1 1 1 2 2 2 0 Probable zinc-ribbon domain DUF4661 PF15576.6 EOO01424.1 - 1.3 8.9 5.6 1.9 8.3 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Zn_ribbon_SprT PF17283.2 EOO01424.1 - 1.7 8.6 6.9 4.7 7.2 1.1 2.1 1 1 1 2 2 2 0 SprT-like zinc ribbon domain DUF4893 PF16233.5 EOO01424.1 - 2.3 7.8 6.0 6.9 6.2 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4893) Mito_carr PF00153.27 EOO01425.1 - 0.0048 16.8 0.0 0.55 10.2 0.0 2.6 2 0 0 2 2 2 2 Mitochondrial carrier protein Fungal_trans PF04082.18 EOO01426.1 - 3.7e-34 118.0 0.9 3.7e-34 118.0 0.9 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain BCDHK_Adom3 PF10436.9 EOO01427.1 - 3.4e-34 118.0 0.1 4.2e-34 117.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase KNOX2 PF03791.13 EOO01427.1 - 0.15 11.6 0.1 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 KNOX2 domain Trns_repr_metal PF02583.17 EOO01427.1 - 0.17 12.3 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor F-box-like PF12937.7 EOO01428.1 - 6.5e-07 29.2 1.4 7.7e-07 28.9 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EOO01428.1 - 2.6e-06 27.2 0.1 8.4e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 F-box domain UIM PF02809.20 EOO01428.1 - 0.0018 18.1 14.7 0.075 13.0 3.2 3.6 3 0 0 3 3 3 2 Ubiquitin interaction motif UQ_con PF00179.26 EOO01429.1 - 4.8e-52 175.3 0.1 5.4e-52 175.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EOO01429.1 - 0.00058 19.6 0.0 0.00064 19.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EOO01429.1 - 0.04 14.2 0.0 0.053 13.8 0.0 1.4 1 1 0 1 1 1 0 RWD domain EMP24_GP25L PF01105.24 EOO01430.1 - 3.1e-46 157.6 2.0 3.5e-46 157.4 2.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4428 PF14471.6 EOO01431.1 - 0.024 14.5 0.2 6 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) SwrA PF17423.2 EOO01431.1 - 0.063 13.3 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Swarming motility protein zinc_ribbon_12 PF11331.8 EOO01431.1 - 2.5 8.0 4.6 6.9 6.6 0.7 2.6 2 1 0 2 2 2 0 Probable zinc-ribbon domain CAP_N PF01213.19 EOO01434.1 - 6.1e-118 393.9 0.6 1e-117 393.2 0.6 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EOO01434.1 - 9e-56 187.8 3.6 1.2e-55 187.4 3.6 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DEC-1_N PF04625.13 EOO01434.1 - 0.0067 15.5 16.8 0.0094 15.0 6.7 2.3 2 0 0 2 2 2 2 DEC-1 protein, N-terminal region TBCC PF07986.12 EOO01434.1 - 0.44 10.3 2.1 0.88 9.3 1.1 1.8 1 1 1 2 2 2 0 Tubulin binding cofactor C TauD PF02668.16 EOO01435.1 - 2.6e-37 129.1 0.2 3.3e-37 128.7 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EOO01435.1 - 0.095 13.4 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF971) MoeA_N PF03453.17 EOO01436.1 - 2.7e-43 147.4 3.4 3.9e-43 146.9 3.4 1.2 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 EOO01436.1 - 3.7e-29 101.2 0.1 1e-28 99.8 0.0 1.8 2 0 0 2 2 2 1 Probable molybdopterin binding domain MoeA_C PF03454.15 EOO01436.1 - 0.0002 21.5 0.1 0.0031 17.7 0.0 2.8 3 0 0 3 3 3 1 MoeA C-terminal region (domain IV) Serinc PF03348.15 EOO01437.1 - 1.5e-161 538.2 10.6 1.6e-161 538.0 10.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) CENP-T_C PF15511.6 EOO01438.1 - 0.023 14.8 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EOO01438.1 - 0.15 12.4 0.0 0.19 12.1 0.0 1.1 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Asparaginase PF00710.20 EOO01439.1 - 1.2e-52 178.2 0.0 1.9e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EOO01439.1 - 2e-26 92.5 0.0 4e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 EOO01439.1 - 2.1e-18 66.7 2.6 1.6e-11 44.7 0.4 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EOO01439.1 - 6.9e-10 38.9 0.0 0.00028 21.2 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EOO01439.1 - 3.7e-08 33.7 0.1 0.00013 22.5 0.1 3.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EOO01439.1 - 8.7e-07 28.8 0.2 0.027 15.0 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EOO01439.1 - 2.6e-06 27.6 0.2 0.00031 21.0 0.3 2.8 1 1 2 3 3 3 1 Ankyrin repeats (many copies) CN_hydrolase PF00795.22 EOO01440.1 - 6.4e-13 48.6 0.0 7e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Thiolase_N PF00108.23 EOO01441.1 - 8.9e-89 297.3 0.9 1.5e-88 296.6 0.9 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EOO01441.1 - 7.3e-38 129.0 0.8 7.3e-38 129.0 0.8 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EOO01441.1 - 3.1e-05 23.7 0.6 6.9e-05 22.5 0.2 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EOO01441.1 - 1.9 8.4 5.1 8.6 6.3 0.1 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HypA PF01155.19 EOO01442.1 - 0.054 13.5 9.8 0.54 10.3 1.3 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-HC5HC2H PF13771.6 EOO01442.1 - 2.3 8.5 9.4 0.11 12.7 2.6 2.1 2 0 0 2 2 2 0 PHD-like zinc-binding domain Ist1 PF03398.14 EOO01443.1 - 1.7e-62 210.2 2.2 4.3e-62 208.9 2.2 1.7 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway TFIID-18kDa PF02269.16 EOO01443.1 - 1.4e-24 85.9 0.5 2.1e-23 82.1 0.0 2.9 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Myc_N PF01056.18 EOO01443.1 - 0.026 14.4 0.5 0.093 12.6 0.2 1.9 2 0 0 2 2 2 0 Myc amino-terminal region Glyco_transf_15 PF01793.16 EOO01444.1 - 6.5e-109 364.1 9.9 7.8e-109 363.9 9.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase NAD_kinase PF01513.21 EOO01445.1 - 5.7e-70 235.8 0.0 1e-69 235.0 0.0 1.4 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EOO01445.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain CXCR4_N PF12109.8 EOO01445.1 - 3.7 7.8 5.9 0.56 10.5 0.7 2.3 2 0 0 2 2 2 0 CXCR4 Chemokine receptor N terminal Sugar_tr PF00083.24 EOO01446.1 - 1.4e-36 126.4 5.4 1.9e-29 102.8 0.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO01446.1 - 7.3e-05 21.9 6.0 7.3e-05 21.9 6.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily NOA36 PF06524.12 EOO01447.1 - 0.38 10.0 2.8 26 4.0 0.0 2.1 2 0 0 2 2 2 0 NOA36 protein adh_short_C2 PF13561.6 EOO01448.1 - 1.3e-53 182.0 0.9 2.8e-53 180.9 0.9 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO01448.1 - 6.9e-34 117.0 2.7 6.5e-33 113.8 2.7 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO01448.1 - 3.8e-07 30.2 0.2 8.5e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 EOO01448.1 - 0.0024 17.2 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 EOO01448.1 - 0.0089 15.5 0.1 0.48 9.8 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EOO01448.1 - 0.027 14.4 0.3 0.043 13.7 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EOO01448.1 - 0.048 13.6 0.6 0.092 12.7 0.3 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 EOO01448.1 - 0.053 14.1 0.4 0.1 13.2 0.4 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent YjeF_N PF03853.15 EOO01448.1 - 0.062 13.2 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Methyltransf_25 PF13649.6 EOO01448.1 - 0.09 13.5 0.1 0.22 12.2 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain HATPase_c PF02518.26 EOO01448.1 - 0.16 12.5 0.0 1.7 9.2 0.0 2.5 4 0 0 4 4 3 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PGA2 PF07543.12 EOO01449.1 - 2.4e-40 137.7 5.4 2.8e-40 137.5 5.4 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 V_ATPase_I PF01496.19 EOO01449.1 - 0.049 11.6 0.7 0.057 11.4 0.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family POT1 PF02765.17 EOO01450.1 - 8e-14 51.7 0.0 1.6e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 IF4E PF01652.18 EOO01451.1 - 1.2e-56 190.9 0.0 1.7e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ribosomal_L4 PF00573.22 EOO01452.1 - 4e-34 118.0 0.1 5.6e-34 117.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EOO01452.1 - 1e-29 102.4 0.5 2.4e-29 101.2 0.5 1.6 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain PigN PF04987.14 EOO01453.1 - 2.5e-117 392.5 36.3 1.9e-66 224.8 16.0 2.5 2 1 1 3 3 3 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EOO01453.1 - 2.9e-10 40.3 3.8 4.2e-09 36.5 3.8 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EOO01453.1 - 9.2e-10 38.4 0.3 1.4e-09 37.8 0.3 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EOO01453.1 - 2.4e-05 23.8 0.0 4.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Kinesin PF00225.23 EOO01454.1 - 1e-112 376.4 1.8 1e-112 376.3 0.2 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EOO01454.1 - 1.1e-25 90.3 0.0 3.9e-25 88.5 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding IFT57 PF10498.9 EOO01454.1 - 0.98 8.3 33.5 0.33 9.9 8.7 3.1 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 MTHFR PF02219.17 EOO01455.1 - 2.2e-100 335.7 0.0 3.3e-100 335.1 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase adh_short PF00106.25 EOO01457.1 - 6.8e-28 97.5 1.1 1.6e-26 93.0 1.1 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO01457.1 - 1.1e-16 61.1 0.6 5.2e-16 58.9 0.6 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO01457.1 - 5.6e-11 42.7 0.0 9.3e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO01457.1 - 2.1e-05 24.1 0.0 3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO01457.1 - 0.0098 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase SWIRM-assoc_1 PF16495.5 EOO01458.1 - 3.7e-32 110.1 6.2 3.7e-32 110.1 6.2 1.7 2 0 0 2 2 2 1 SWIRM-associated region 1 SWIRM PF04433.17 EOO01458.1 - 5.5e-32 110.0 0.1 1.2e-31 108.9 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 EOO01458.1 - 9.6e-10 38.5 0.0 2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EOO01458.1 - 1.2e-05 25.4 0.0 2.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3439 PF11921.8 EOO01458.1 - 0.011 15.8 3.3 0.027 14.4 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SANT_DAMP1_like PF16282.5 EOO01458.1 - 0.011 15.9 0.1 0.022 14.9 0.1 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Metallophos PF00149.28 EOO01459.1 - 5.5e-24 85.8 0.1 4.2e-11 43.7 0.0 2.4 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Pet127 PF08634.10 EOO01460.1 - 2.5e-92 309.2 1.8 2.5e-92 309.2 1.8 1.7 2 0 0 2 2 2 1 Mitochondrial protein Pet127 GATase PF00117.28 EOO01461.1 - 4.1e-46 157.1 0.0 5.7e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EOO01461.1 - 4.3e-46 155.9 0.0 6.5e-46 155.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 EOO01461.1 - 3.5e-05 23.7 0.3 0.0037 17.1 0.3 2.8 1 1 0 1 1 1 1 Peptidase C26 NAD_binding_5 PF07994.12 EOO01461.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Septin PF00735.18 EOO01462.1 - 2.7e-114 381.2 0.2 4.2e-114 380.6 0.2 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EOO01462.1 - 2.1e-07 31.0 0.0 4.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EOO01462.1 - 7e-06 25.7 3.9 7.7e-05 22.3 0.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EOO01462.1 - 8.3e-06 25.8 1.8 3.1e-05 23.9 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 EOO01462.1 - 0.0019 18.5 0.7 0.0053 17.0 0.1 2.1 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 EOO01462.1 - 0.0025 17.3 0.1 0.0052 16.3 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 EOO01462.1 - 0.0035 17.5 0.1 0.0078 16.4 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EOO01462.1 - 0.008 15.5 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 EOO01462.1 - 0.0091 15.1 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Casc1_N PF15927.5 EOO01462.1 - 0.0094 15.7 10.6 0.024 14.3 10.6 1.6 1 0 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus AAA_24 PF13479.6 EOO01462.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 EOO01462.1 - 0.02 14.5 0.5 0.062 12.9 0.5 1.8 1 1 0 1 1 1 0 Ras family KAP_NTPase PF07693.14 EOO01462.1 - 0.027 13.7 0.0 0.036 13.3 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain T2SSE PF00437.20 EOO01462.1 - 0.045 12.8 0.4 0.18 10.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 EOO01462.1 - 0.048 13.6 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 EOO01462.1 - 0.049 14.0 1.5 0.087 13.2 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EOO01462.1 - 0.05 14.1 0.2 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter FOXP-CC PF16159.5 EOO01462.1 - 0.065 13.9 1.2 0.065 13.9 1.2 2.5 2 1 1 3 3 2 0 FOXP coiled-coil domain Sigma54_activat PF00158.26 EOO01462.1 - 0.082 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 EOO01462.1 - 0.12 12.0 0.1 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EOO01462.1 - 0.14 11.9 0.4 8.3 6.2 0.1 2.6 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 EOO01462.1 - 0.14 12.6 0.0 0.43 11.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Dynamin_N PF00350.23 EOO01462.1 - 0.57 10.2 7.4 4.2 7.4 0.1 3.1 2 1 1 3 3 3 0 Dynamin family Ribosomal_L6e PF01159.19 EOO01462.1 - 1.6 9.3 6.6 7.8 7.1 0.2 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e FUSC PF04632.12 EOO01462.1 - 2.4 6.6 4.1 3.2 6.2 4.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_11 PF13086.6 EOO01462.1 - 4.7 6.9 7.6 23 4.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain Myc-LZ PF02344.15 EOO01462.1 - 8.5 6.6 8.6 7.5 6.7 2.6 3.1 2 1 0 2 2 2 0 Myc leucine zipper domain IGPD PF00475.18 EOO01463.1 - 4.4e-60 202.2 0.7 5.9e-60 201.8 0.7 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase PLDc PF00614.22 EOO01464.1 - 1 9.7 3.3 4.1 7.8 0.0 3.5 4 1 0 4 4 4 0 Phospholipase D Active site motif ArfGap PF01412.18 EOO01465.1 - 9.2e-32 109.6 0.1 1.6e-31 108.8 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Tape_meas_lam_C PF09718.10 EOO01465.1 - 0.11 12.7 0.2 0.33 11.1 0.2 1.8 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) LapA_dom PF06305.11 EOO01466.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 EOO01467.1 - 1.7e-24 86.6 0.0 2.7e-24 85.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO01467.1 - 1.3e-08 34.5 0.0 4.7e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EOO01467.1 - 0.0023 17.9 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EOO01467.1 - 0.016 14.2 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain adh_short PF00106.25 EOO01468.1 - 2e-19 69.8 0.0 1.5e-14 53.9 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EOO01468.1 - 9.3e-11 41.7 0.0 7.3e-10 38.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO01468.1 - 9.5e-06 25.6 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 KR domain PhoD PF09423.10 EOO01469.1 - 3.7e-36 124.9 1.6 1.2e-19 70.5 0.0 2.6 1 1 1 2 2 2 2 PhoD-like phosphatase LRR_9 PF14580.6 EOO01470.1 - 5.9e-56 188.7 0.3 1e-55 187.9 0.1 1.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 EOO01470.1 - 3.7e-07 30.4 2.6 0.00041 20.7 2.9 3.2 2 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EOO01470.1 - 2e-05 24.3 3.7 2.2e-05 24.1 1.2 2.5 3 0 0 3 3 3 1 Leucine rich repeat DUF4349 PF14257.6 EOO01470.1 - 0.0017 17.9 2.4 0.0028 17.1 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) PspB PF06667.12 EOO01470.1 - 0.34 11.0 1.4 0.97 9.5 1.4 1.8 1 0 0 1 1 1 0 Phage shock protein B Exo84_C PF16528.5 EOO01473.1 - 7.3e-79 264.4 0.5 7.3e-79 264.4 0.5 2.3 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EOO01473.1 - 2.6e-16 59.5 3.1 2.6e-16 59.5 3.1 2.2 3 0 0 3 3 3 1 Vps51/Vps67 AP2 PF00847.20 EOO01473.1 - 0.02 15.1 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 AP2 domain TSC22 PF01166.18 EOO01473.1 - 0.02 15.2 0.7 16 5.9 0.0 3.4 2 0 0 2 2 2 0 TSC-22/dip/bun family APG6_N PF17675.1 EOO01473.1 - 0.22 12.1 11.7 0.08 13.5 3.3 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF2383 PF09537.10 EOO01473.1 - 0.54 10.6 3.7 0.54 10.6 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Prominin PF05478.11 EOO01473.1 - 3.3 5.6 7.3 0.82 7.5 1.6 2.2 2 0 0 2 2 2 0 Prominin Thioredoxin PF00085.20 EOO01474.1 - 3.5e-58 194.0 0.0 1.3e-28 99.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EOO01474.1 - 4e-26 91.7 2.4 4.7e-26 91.5 1.1 1.8 2 0 0 2 2 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 EOO01474.1 - 2.3e-15 57.0 0.0 9.6e-08 32.5 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EOO01474.1 - 2.1e-13 50.3 0.0 1.3e-05 24.7 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EOO01474.1 - 2.9e-09 37.1 0.0 0.0013 19.0 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 EOO01474.1 - 1.7e-08 34.5 0.0 0.005 16.7 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 EOO01474.1 - 2.3e-08 34.1 0.0 0.0078 16.4 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like TraF PF13728.6 EOO01474.1 - 1.5e-05 24.9 0.0 0.0029 17.5 0.0 2.9 2 1 0 2 2 2 1 F plasmid transfer operon protein Redoxin PF08534.10 EOO01474.1 - 0.00011 22.0 0.1 0.3 10.8 0.0 2.5 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.6 EOO01474.1 - 0.00018 21.3 0.0 0.3 10.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29_N PF07912.13 EOO01474.1 - 0.00058 20.0 0.4 0.011 15.8 0.0 2.8 3 0 0 3 3 3 1 ERp29, N-terminal domain Glutaredoxin PF00462.24 EOO01474.1 - 0.0048 17.1 0.0 6.3 7.1 0.0 2.8 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin_4 PF13462.6 EOO01474.1 - 0.0069 16.6 0.7 4 7.6 0.4 2.9 2 1 0 2 2 2 2 Thioredoxin HyaE PF07449.11 EOO01474.1 - 0.0078 16.2 0.0 0.26 11.3 0.0 2.6 3 0 0 3 3 2 1 Hydrogenase-1 expression protein HyaE DUF4449 PF14613.6 EOO01474.1 - 0.029 14.5 0.5 0.055 13.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) DDE_Tnp_1_2 PF13586.6 EOO01474.1 - 0.1 13.0 0.0 0.77 10.2 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain Csm4_C PF17953.1 EOO01474.1 - 0.17 11.8 0.9 21 5.1 0.0 3.2 4 0 0 4 4 4 0 CRISPR Csm4 C-terminal domain WSC PF01822.19 EOO01475.1 - 1.8e-33 114.6 21.2 1.1e-17 64.0 2.8 2.1 2 0 0 2 2 2 2 WSC domain Cys_Met_Meta_PP PF01053.20 EOO01476.1 - 3.8e-118 394.4 0.0 4.2e-118 394.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EOO01476.1 - 0.00011 21.3 0.0 0.0004 19.4 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EOO01476.1 - 0.00078 18.7 0.1 0.0011 18.2 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II NIR_SIR_ferr PF03460.17 EOO01476.1 - 0.073 12.9 0.1 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain ZFYVE21_C PF16696.5 EOO01476.1 - 0.18 11.7 0.2 6.4 6.7 0.1 2.6 3 0 0 3 3 3 0 Zinc finger FYVE domain-containing protein 21 C-terminus Exo_endo_phos PF03372.23 EOO01477.1 - 8.3e-13 48.4 0.5 5.2e-11 42.5 0.5 2.4 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.6 EOO01477.1 - 0.13 12.3 0.1 1.2 9.2 0.0 2.6 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DKCLD PF08068.12 EOO01478.1 - 7.4e-33 112.4 0.5 1.2e-31 108.6 0.4 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 EOO01478.1 - 2.1e-23 82.2 0.7 3.6e-23 81.5 0.7 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 EOO01478.1 - 9.3e-23 81.2 0.1 5.3e-20 72.3 0.1 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 EOO01478.1 - 1.6e-20 72.9 0.5 2.9e-20 72.0 0.5 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EOO01478.1 - 0.00045 20.4 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain Med19 PF10278.9 EOO01478.1 - 0.68 9.9 7.1 1.3 8.9 7.1 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 PGAP1 PF07819.13 EOO01479.1 - 3.3e-94 314.9 0.0 4e-94 314.6 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EOO01479.1 - 1.8e-05 25.4 0.0 2.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EOO01479.1 - 0.00074 19.2 0.0 0.0023 17.6 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EOO01479.1 - 0.0023 17.3 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 EOO01479.1 - 0.006 16.3 0.0 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 Putative esterase DUF915 PF06028.11 EOO01479.1 - 0.023 14.1 0.0 0.42 9.9 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 EOO01479.1 - 0.03 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EOO01479.1 - 0.037 13.9 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Lipase_3 PF01764.25 EOO01479.1 - 0.098 12.5 0.0 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Metallophos PF00149.28 EOO01480.1 - 3.5e-38 132.2 0.5 5.6e-38 131.5 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EOO01480.1 - 0.012 16.0 0.1 0.024 15.1 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Tau95 PF09734.9 EOO01481.1 - 2.2e-37 129.0 0.1 4.4e-37 128.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EOO01481.1 - 2.8e-34 118.0 0.0 5.9e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 Tau95 Triple barrel domain Cwf_Cwc_15 PF04889.12 EOO01481.1 - 0.011 15.5 9.3 0.025 14.3 9.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EOO01481.1 - 1.6 6.8 16.4 2.1 6.5 16.4 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 EOO01481.1 - 7.5 6.0 13.4 12 5.3 13.4 1.3 1 0 0 1 1 1 0 PPP4R2 EBP PF05241.12 EOO01482.1 - 2.5e-70 235.5 6.0 2.9e-70 235.3 6.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein LMBR1 PF04791.16 EOO01482.1 - 0.0066 15.4 0.6 0.0091 14.9 0.6 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein TMEM208_SND2 PF05620.11 EOO01482.1 - 1.1 9.0 7.4 0.24 11.1 0.8 2.3 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF3302 PF11742.8 EOO01482.1 - 3.8 7.7 7.0 1.9 8.7 1.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3302) WD40 PF00400.32 EOO01484.1 - 1.1e-18 67.3 10.6 1.2e-05 26.0 0.5 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO01484.1 - 9.6e-09 35.4 0.0 0.0089 16.3 0.0 4.9 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EOO01484.1 - 2e-05 24.3 7.7 0.002 17.8 3.0 2.3 1 1 2 3 3 3 2 PQQ-like domain PQQ PF01011.21 EOO01484.1 - 0.008 16.1 0.7 33 4.6 0.1 4.4 4 0 0 4 4 4 0 PQQ enzyme repeat Gp5_C PF06715.12 EOO01484.1 - 0.07 13.3 0.5 1.2 9.5 0.1 2.7 2 0 0 2 2 2 0 Gp5 C-terminal repeat (3 copies) Nup160 PF11715.8 EOO01484.1 - 0.091 11.4 1.0 7.8 5.0 0.0 2.8 3 1 0 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EOO01484.1 - 2 9.0 14.7 6.9 7.3 0.0 5.1 5 1 1 6 6 6 0 PQQ-like domain SLAC1 PF03595.17 EOO01485.1 - 9.9e-58 195.9 31.8 1.6e-57 195.2 31.8 1.3 1 0 0 1 1 1 1 Voltage-dependent anion channel Wyosine_form PF08608.12 EOO01485.1 - 3.7e-23 81.6 0.0 8e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 EOO01485.1 - 3.9e-22 79.4 0.1 8.4e-22 78.3 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 EOO01485.1 - 1.4e-06 28.6 0.1 1e-05 25.7 0.1 2.3 2 1 0 2 2 2 1 Flavodoxin DNA_pol_alpha_N PF12254.8 EOO01485.1 - 0.11 12.7 0.0 13 5.9 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal CENP-S PF15630.6 EOO01486.1 - 1.1e-32 112.2 0.0 2.1e-32 111.3 0.0 1.4 1 1 1 2 2 2 1 CENP-S protein CENP-T_C PF15511.6 EOO01486.1 - 3.7e-06 27.0 0.2 5.8e-06 26.4 0.1 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold GFA PF04828.14 EOO01487.1 - 8.6e-09 35.6 1.2 0.00029 21.1 0.0 2.9 4 0 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 EOO01487.1 - 0.011 15.4 1.3 0.011 15.4 1.3 2.9 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 EOO01487.1 - 0.17 11.8 6.5 0.66 9.9 0.1 3.3 4 0 0 4 4 4 0 Nudix N-terminal zf-CSL PF05207.13 EOO01487.1 - 0.66 9.8 12.3 0.31 10.8 1.8 2.8 3 0 0 3 3 3 0 CSL zinc finger zinc_ribbon_2 PF13240.6 EOO01487.1 - 2.5 7.9 10.4 4.9 7.0 0.3 3.5 3 0 0 3 3 3 0 zinc-ribbon domain PA-IIL PF07472.11 EOO01488.1 - 0.09 13.1 0.2 0.18 12.1 0.2 1.5 1 0 0 1 1 1 0 Fucose-binding lectin II (PA-IIL) FMO-like PF00743.19 EOO01489.1 - 1e-39 136.4 0.0 3.2e-23 82.0 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EOO01489.1 - 1.8e-13 50.5 1.6 1.6e-07 30.9 0.3 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EOO01489.1 - 1.8e-13 50.4 0.0 2.5e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EOO01489.1 - 7.4e-12 45.5 0.0 3.6e-11 43.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EOO01489.1 - 2.7e-10 39.9 0.6 4.3e-08 32.7 0.1 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EOO01489.1 - 4.6e-10 39.6 0.1 0.002 17.8 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 EOO01489.1 - 3.3e-06 26.5 0.0 0.00014 21.2 0.0 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EOO01489.1 - 9.5e-06 25.8 0.0 3.4e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EOO01489.1 - 0.00024 20.5 0.0 0.5 9.6 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase MCRA PF06100.11 EOO01489.1 - 0.00034 19.6 0.4 0.0012 17.7 0.0 1.8 2 0 0 2 2 2 1 MCRA family FAD_binding_2 PF00890.24 EOO01489.1 - 0.0015 17.7 0.0 0.14 11.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EOO01489.1 - 0.0017 17.7 0.1 0.0085 15.4 0.0 2.1 3 0 0 3 3 3 1 FAD binding domain TrkA_N PF02254.18 EOO01489.1 - 0.0046 17.2 0.0 2.1 8.7 0.0 2.7 3 0 0 3 3 3 1 TrkA-N domain HI0933_like PF03486.14 EOO01489.1 - 0.024 13.4 0.1 0.43 9.2 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.6 EOO01489.1 - 0.034 14.6 0.0 18 5.8 0.0 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 EOO01489.1 - 0.04 14.0 0.0 0.55 10.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EOO01489.1 - 0.048 14.2 0.6 6.1 7.5 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EOO01489.1 - 0.37 9.8 1.8 3.9 6.5 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF2993 PF11209.8 EOO01490.1 - 0.027 14.7 0.0 0.031 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2993) Mak16 PF04874.14 EOO01491.1 - 0.1 13.2 0.1 0.92 10.2 0.1 2.2 2 0 0 2 2 2 0 Mak16 protein C-terminal region WD40 PF00400.32 EOO01492.1 - 1.1e-39 133.6 27.1 1.4e-08 35.3 0.0 12.6 14 0 0 14 14 14 7 WD domain, G-beta repeat Utp12 PF04003.12 EOO01492.1 - 7.9e-26 90.5 0.0 1.2e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EOO01492.1 - 6.1e-21 74.5 0.0 0.0042 17.4 0.0 10.1 4 2 6 11 11 11 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EOO01492.1 - 6e-09 35.3 0.9 1.7 7.5 0.0 6.1 3 1 1 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EOO01492.1 - 6.8e-06 26.1 0.8 0.19 11.6 0.1 5.7 6 2 2 8 8 8 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 EOO01492.1 - 0.012 15.0 0.2 16 4.7 0.0 4.0 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 EOO01492.1 - 0.016 14.6 0.0 0.24 10.7 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain Nup160 PF11715.8 EOO01492.1 - 0.05 12.2 1.9 11 4.5 0.0 3.9 3 2 1 4 4 4 0 Nucleoporin Nup120/160 PD40 PF07676.12 EOO01492.1 - 0.15 12.0 1.2 26 4.9 0.0 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SKIP_SNW PF02731.15 EOO01493.1 - 5.2e-72 240.8 4.7 5.2e-72 240.8 4.7 2.7 3 0 0 3 3 3 1 SKIP/SNW domain MFMR_assoc PF16596.5 EOO01493.1 - 0.083 13.4 5.6 3.4 8.1 4.1 2.4 2 0 0 2 2 2 0 Disordered region downstream of MFMR USP7_ICP0_bdg PF12436.8 EOO01495.1 - 4.6e-88 294.6 0.0 6.6e-87 290.8 0.0 2.7 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EOO01495.1 - 7.4e-59 198.9 4.2 1.4e-56 191.5 1.0 3.7 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 EOO01495.1 - 1.4e-47 162.4 2.2 2.9e-47 161.3 1.7 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EOO01495.1 - 2.2e-19 70.3 0.3 5.4e-19 68.9 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EOO01495.1 - 5.6e-11 42.6 0.0 2.2e-10 40.7 0.0 2.0 1 0 0 1 1 1 1 MATH domain TPR_10 PF13374.6 EOO01496.1 - 0.0018 18.1 0.3 0.25 11.2 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EOO01496.1 - 0.0087 16.3 0.0 0.39 11.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EOO01496.1 - 0.035 14.1 0.2 0.12 12.5 0.0 2.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EOO01496.1 - 0.34 11.1 1.4 13 6.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L11 PF00298.19 EOO01497.1 - 7.4e-28 96.9 0.0 9e-28 96.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Grg1 PF11034.8 EOO01498.1 - 3e-32 110.6 11.5 3.3e-32 110.5 11.5 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 COPI_assoc PF08507.10 EOO01499.1 - 2.2e-35 121.6 6.9 2.3e-35 121.5 6.9 1.0 1 0 0 1 1 1 1 COPI associated protein UCR_Fe-S_N PF10399.9 EOO01499.1 - 0.083 12.3 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal ATP-synt_C PF00137.21 EOO01500.1 - 3.6e-26 91.3 30.0 1.7e-15 57.1 11.4 2.2 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 EOO01500.1 - 0.005 16.2 1.9 0.095 12.0 0.0 2.1 2 0 0 2 2 2 2 SMODS and SLOG-associating 2TM effector domain family 5 DUF3671 PF12420.8 EOO01500.1 - 0.14 12.3 0.2 0.14 12.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function DNA_mis_repair PF01119.19 EOO01501.1 - 1.1e-19 70.3 0.0 2.6e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 EOO01501.1 - 1.1e-16 61.0 0.1 2.5e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 EOO01501.1 - 1e-11 44.8 0.7 1.5e-10 41.0 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EOO01501.1 - 7e-07 29.7 0.5 3.1e-06 27.6 0.0 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIIF_alpha PF05793.12 EOO01501.1 - 0.11 11.0 31.5 0.19 10.3 31.5 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Flavi_NS2B PF01002.19 EOO01501.1 - 0.27 11.1 1.6 0.86 9.5 1.6 1.8 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B Aldo_ket_red PF00248.21 EOO01502.1 - 4.9e-65 219.6 0.0 5.6e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Asp PF00026.23 EOO01503.1 - 7e-08 32.2 7.1 0.00073 19.0 7.1 3.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EOO01503.1 - 0.049 13.9 3.2 5 7.3 0.2 3.3 2 1 1 3 3 3 0 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EOO01503.1 - 0.078 12.7 0.2 0.71 9.6 0.0 2.1 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Cohesin_load PF10345.9 EOO01504.1 - 3.6e-120 402.2 0.4 4.1e-120 402.0 0.4 1.0 1 0 0 1 1 1 1 Cohesin loading factor PfkB PF00294.24 EOO01505.1 - 2.3e-56 191.3 0.7 2.7e-56 191.1 0.7 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF4748 PF15932.5 EOO01506.1 - 2.2e-14 53.0 0.2 3.1e-14 52.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) Pyr_redox_2 PF07992.14 EOO01507.1 - 3.8e-21 75.6 0.9 4.8e-21 75.2 0.9 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EOO01507.1 - 0.00012 21.3 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EOO01507.1 - 0.00027 21.5 0.3 0.00051 20.5 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Myosin_N PF02736.19 EOO01507.1 - 0.0012 18.6 0.2 0.012 15.4 0.0 2.4 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain DUF4858 PF16150.5 EOO01507.1 - 0.043 13.8 0.1 0.083 12.9 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4858) ThiF PF00899.21 EOO01507.1 - 0.058 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 ThiF family IF-2B PF01008.17 EOO01508.1 - 2.7e-39 135.1 0.0 3.7e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family SpoU_sub_bind PF08032.12 EOO01508.1 - 0.03 14.6 0.0 0.16 12.2 0.0 2.3 2 1 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding MAS20 PF02064.15 EOO01509.1 - 2.4e-42 144.1 0.3 3.1e-42 143.7 0.3 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor Sel_put PF04328.13 EOO01509.1 - 0.024 14.7 0.2 0.046 13.7 0.2 1.5 1 1 0 1 1 1 0 Selenoprotein, putative OEP PF02321.18 EOO01509.1 - 0.042 13.6 3.8 0.083 12.7 3.8 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein ABA_WDS PF02496.16 EOO01509.1 - 0.082 13.4 2.2 0.18 12.3 0.1 2.1 1 1 1 2 2 2 0 ABA/WDS induced protein CSRNP_N PF16019.5 EOO01509.1 - 0.084 12.8 0.8 0.11 12.4 0.8 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus PAP_PilO PF06864.12 EOO01509.1 - 0.12 11.2 0.9 0.15 10.9 0.9 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) AP-5_subunit_s1 PF15001.6 EOO01509.1 - 0.13 12.3 1.4 0.17 11.9 1.4 1.1 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 DUF3824 PF12868.7 EOO01509.1 - 0.24 12.1 4.0 0.39 11.4 4.0 1.5 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) SNF2_N PF00176.23 EOO01510.1 - 1.8e-71 240.7 0.0 2.8e-71 240.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EOO01510.1 - 4.3e-19 68.2 0.0 9.3e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EOO01510.1 - 9.9e-15 54.9 0.0 3.9e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EOO01510.1 - 2.8e-10 39.9 11.0 6.4e-10 38.7 11.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EOO01510.1 - 9.2e-10 38.2 11.1 1e-09 38.1 7.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EOO01510.1 - 2.7e-08 33.6 10.9 2.7e-08 33.6 10.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EOO01510.1 - 3.5e-08 33.7 10.0 3.5e-08 33.7 10.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EOO01510.1 - 9.6e-07 28.7 8.9 2.9e-06 27.2 8.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EOO01510.1 - 1.6e-06 28.0 9.6 3.6e-06 26.8 9.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EOO01510.1 - 3.2e-06 27.2 9.3 6.6e-06 26.2 9.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ResIII PF04851.15 EOO01510.1 - 5.5e-05 23.2 0.0 0.00017 21.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-rbx1 PF12678.7 EOO01510.1 - 5.6e-05 23.4 8.6 0.00019 21.6 8.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EOO01510.1 - 0.00042 20.1 8.0 0.00042 20.1 8.0 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EOO01510.1 - 0.0015 18.3 4.1 0.0036 17.2 4.1 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EOO01510.1 - 0.0058 16.6 3.5 0.013 15.6 3.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.14 EOO01510.1 - 0.0082 16.0 1.1 0.9 9.4 0.1 2.7 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-RING_10 PF16685.5 EOO01510.1 - 0.0094 16.1 6.5 0.028 14.6 6.5 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EOO01510.1 - 0.039 13.7 7.9 0.15 11.9 8.0 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain HAD_SAK_2 PF18143.1 EOO01510.1 - 0.083 13.2 0.5 0.55 10.5 0.1 2.5 2 1 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins zf-Nse PF11789.8 EOO01510.1 - 0.18 11.6 9.0 0.26 11.2 7.3 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 EOO01510.1 - 1.5 8.9 5.2 3.4 7.8 5.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-P11 PF03854.14 EOO01510.1 - 1.9 8.2 10.1 0.35 10.6 1.5 2.7 2 1 1 3 3 3 0 P-11 zinc finger zinc-ribbons_6 PF07191.12 EOO01510.1 - 3.3 7.8 5.7 6.6 6.8 5.7 1.5 1 0 0 1 1 1 0 zinc-ribbons RE_CfrBI PF09516.10 EOO01511.1 - 0.042 13.3 0.6 0.52 9.7 0.2 2.0 2 0 0 2 2 2 0 CfrBI restriction endonuclease TFIIA_gamma_C PF02751.14 EOO01512.1 - 2.6e-24 85.1 0.7 5e-24 84.2 0.7 1.5 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 EOO01512.1 - 3.6e-24 84.5 0.3 5e-24 84.1 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain FAD_binding_4 PF01565.23 EOO01513.1 - 2.7e-26 92.0 0.5 4.3e-26 91.3 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EOO01513.1 - 0.00012 22.1 0.1 0.00037 20.5 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.14 EOO01513.1 - 0.02 14.7 0.0 0.75 9.6 0.0 2.3 2 0 0 2 2 2 0 D-arabinono-1,4-lactone oxidase Clat_adaptor_s PF01217.20 EOO01514.1 - 1.7e-56 190.1 1.6 1.8e-56 190.0 1.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain FAD_binding_1 PF00667.20 EOO01515.1 - 1.3e-28 100.1 0.0 2.5e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EOO01515.1 - 3.1e-23 82.6 0.0 5.9e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EOO01515.1 - 9.6e-11 42.3 0.1 8.7e-08 32.8 0.0 2.9 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EOO01515.1 - 0.00044 20.5 0.0 0.001 19.3 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin domain UCH PF00443.29 EOO01516.1 - 1e-26 94.0 0.0 1.6e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EOO01516.1 - 2.7e-12 46.8 0.1 5.2e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EOO01516.1 - 0.003 17.2 0.1 0.025 14.2 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1064 PF06356.11 EOO01516.1 - 0.16 12.3 0.1 0.36 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1064) UVR PF02151.19 EOO01516.1 - 0.21 11.4 0.6 0.65 9.8 0.6 1.8 1 0 0 1 1 1 0 UvrB/uvrC motif DUF3112 PF11309.8 EOO01517.1 - 5.8e-12 45.5 12.3 1.7e-07 30.9 0.4 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) DUF3810 PF12725.7 EOO01517.1 - 4.4 6.6 6.9 2.5 7.4 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) LapA_dom PF06305.11 EOO01517.1 - 5.4 6.9 0.0 5.4 6.9 0.0 3.8 4 1 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Clr2_transil PF16761.5 EOO01519.1 - 1.2e-16 61.3 1.2 2.3e-16 60.4 1.2 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 EOO01519.1 - 8e-14 52.6 0.1 7.9e-13 49.4 0.1 2.4 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 DUF3402 PF11882.8 EOO01520.1 - 3.1e-150 501.3 0.1 3.5e-150 501.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) DUF4931 PF16285.5 EOO01520.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) ETF PF01012.21 EOO01521.1 - 2.6e-44 151.3 1.5 4.1e-44 150.6 1.5 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EOO01521.1 - 3.5e-34 116.7 0.4 8.7e-34 115.4 0.4 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain DnaJ_C PF01556.18 EOO01522.1 - 3.3e-38 131.1 1.1 4.3e-38 130.7 1.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EOO01522.1 - 2.5e-27 94.8 2.0 4.1e-27 94.1 2.0 1.3 1 0 0 1 1 1 1 DnaJ domain B56 PF01603.20 EOO01523.1 - 2.8e-193 642.6 4.7 3.3e-193 642.3 4.7 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 EOO01523.1 - 0.00014 21.8 1.6 0.32 10.9 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal WD40 PF00400.32 EOO01524.1 - 5.8e-11 42.8 12.9 6.5e-06 26.8 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO01524.1 - 0.013 15.8 0.2 1.1 9.5 0.0 3.4 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain HAD_2 PF13419.6 EOO01525.1 - 1.1e-22 81.0 0.0 1.4e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EOO01525.1 - 9.1e-11 42.4 0.0 1.5e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 EOO01525.1 - 1.4e-06 28.2 0.0 0.00051 19.8 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_like PF13242.6 EOO01525.1 - 9.3e-06 25.6 0.1 1.8e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EOO01525.1 - 0.001 19.5 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UDPG_MGDP_dh_C PF03720.15 EOO01525.1 - 0.026 15.0 0.1 0.22 12.0 0.0 2.3 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain PAP2 PF01569.21 EOO01526.1 - 8.2e-12 45.1 5.4 8.2e-12 45.1 5.4 2.4 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 EOO01526.1 - 0.011 15.8 0.1 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 Divergent PAP2 family Phage_holin_3_1 PF05106.12 EOO01526.1 - 0.23 11.9 6.2 5.6 7.5 1.4 2.3 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) ATP_bind_1 PF03029.17 EOO01527.1 - 6.7e-70 235.6 0.0 9.3e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Herpes_UL32 PF06070.11 EOO01527.1 - 0.12 10.1 0.1 0.15 9.7 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF5301 PF17225.3 EOO01528.1 - 0.059 13.8 5.3 0.12 12.8 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5300) CDC45 PF02724.14 EOO01528.1 - 0.48 8.7 7.9 0.51 8.6 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4554 PF15091.6 EOO01528.1 - 2.6 6.8 7.5 3.6 6.4 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Zn_clus PF00172.18 EOO01529.1 - 7.2e-09 35.6 12.5 1.5e-08 34.6 12.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EOO01529.1 - 0.0032 16.4 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NepR PF18557.1 EOO01529.1 - 0.69 9.6 4.7 0.69 9.6 0.1 2.3 2 0 0 2 2 2 0 Anti-sigma factor NepR Svf1_C PF17187.4 EOO01530.1 - 6.4e-61 205.0 0.0 1.7e-60 203.6 0.0 1.7 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EOO01530.1 - 1.2e-51 175.1 0.0 1.7e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain KH_4 PF13083.6 EOO01530.1 - 0.01 15.7 0.0 0.033 14.1 0.0 1.9 2 0 0 2 2 2 0 KH domain LPD18 PF18832.1 EOO01530.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 18 MCM PF00493.23 EOO01531.1 - 1.1e-97 325.6 0.1 1.7e-97 324.9 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EOO01531.1 - 2.9e-31 107.9 0.0 5.4e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EOO01531.1 - 7.2e-24 84.0 1.0 1.6e-23 82.9 1.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EOO01531.1 - 8.3e-11 42.4 0.0 2.4e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EOO01531.1 - 4.6e-07 29.4 0.0 5.4e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EOO01531.1 - 0.0035 17.2 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EOO01531.1 - 0.018 14.7 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Fungal_trans_2 PF11951.8 EOO01532.1 - 0.0016 17.3 0.0 0.0026 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GTP_EFTU PF00009.27 EOO01533.1 - 9.9e-57 191.6 0.0 1.3e-56 191.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EOO01533.1 - 1.6e-25 89.6 0.0 3.8e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EOO01533.1 - 2.3e-16 59.9 3.4 2.3e-16 59.9 3.4 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EOO01533.1 - 4.6e-05 23.5 0.0 8.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EOO01533.1 - 0.0013 18.7 0.1 0.0034 17.3 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 EOO01533.1 - 0.026 14.1 0.1 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EOO01533.1 - 0.089 12.5 0.2 17 5.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 EOO01534.1 - 2.4e-38 131.5 0.0 4.4e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EOO01534.1 - 2.3e-09 36.9 0.1 5e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EOO01534.1 - 6.5e-06 26.6 0.3 0.00036 21.0 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EOO01534.1 - 1.1e-05 25.5 0.0 2.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EOO01534.1 - 1.1e-05 25.2 0.0 2.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EOO01534.1 - 1.3e-05 25.5 0.2 0.0084 16.4 0.0 3.4 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 EOO01534.1 - 3.2e-05 24.0 0.0 0.00032 20.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EOO01534.1 - 7.2e-05 23.0 0.0 0.00022 21.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EOO01534.1 - 0.0013 18.1 0.1 0.0038 16.7 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 EOO01534.1 - 0.0021 17.5 0.0 2.1 7.7 0.0 2.4 1 1 1 2 2 2 2 Bacterial TniB protein RNA_helicase PF00910.22 EOO01534.1 - 0.0036 17.7 0.0 0.013 15.9 0.0 2.1 2 0 0 2 2 1 1 RNA helicase IstB_IS21 PF01695.17 EOO01534.1 - 0.0039 17.0 0.0 0.008 15.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EOO01534.1 - 0.0043 17.2 1.3 0.006 16.7 0.0 2.1 3 0 0 3 3 1 1 AAA domain NACHT PF05729.12 EOO01534.1 - 0.0077 16.2 0.0 0.02 14.8 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 EOO01534.1 - 0.008 15.8 1.0 0.068 12.7 0.1 2.8 3 1 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 EOO01534.1 - 0.0087 15.8 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 EOO01534.1 - 0.018 15.6 2.5 0.042 14.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 EOO01534.1 - 0.024 13.8 0.0 0.048 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 EOO01534.1 - 0.024 14.6 0.0 0.12 12.3 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 EOO01534.1 - 0.024 14.7 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 EOO01534.1 - 0.031 14.0 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EOO01534.1 - 0.033 14.1 0.0 0.072 13.0 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 EOO01534.1 - 0.035 13.3 0.0 0.18 11.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 EOO01534.1 - 0.041 14.1 0.0 0.16 12.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 EOO01534.1 - 0.049 12.9 0.3 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 EOO01534.1 - 0.053 13.9 0.6 0.33 11.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 EOO01534.1 - 0.062 12.5 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain YqaJ PF09588.10 EOO01534.1 - 0.065 13.4 0.1 0.4 10.8 0.0 2.2 2 1 1 3 3 3 0 YqaJ-like viral recombinase domain AAA_7 PF12775.7 EOO01534.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 EOO01534.1 - 0.075 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EOO01534.1 - 0.085 13.4 0.0 0.19 12.2 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Bac_DnaA PF00308.18 EOO01534.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Viral_helicase1 PF01443.18 EOO01534.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.17 EOO01534.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 tRNA-synt_1g PF09334.11 EOO01535.1 - 1.5e-139 465.2 0.3 2.9e-137 457.6 0.3 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EOO01535.1 - 1.4e-05 23.5 3.0 0.0036 15.6 0.0 2.9 4 0 0 4 4 4 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EOO01535.1 - 0.00091 19.2 0.3 0.0033 17.4 0.1 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA K_channel_TID PF07941.11 EOO01535.1 - 0.36 11.3 7.2 0.71 10.4 7.2 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Atrophin-1 PF03154.15 EOO01535.1 - 1.5 7.1 8.4 2 6.6 8.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF1682 PF07946.14 EOO01535.1 - 2.9 7.0 10.0 4.9 6.2 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CDO_I PF05995.12 EOO01536.1 - 2e-05 24.0 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Cysteine dioxygenase type I Methyltransf_33 PF10017.9 EOO01537.1 - 9.3e-75 251.6 0.0 1.4e-74 251.0 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 EOO01537.1 - 2.7e-20 73.0 0.3 3.1e-19 69.6 0.3 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EOO01537.1 - 0.072 13.6 0.0 0.21 12.1 0.0 1.9 1 0 0 1 1 1 0 DinB superfamily SAP PF02037.27 EOO01538.1 - 3.8e-13 48.9 0.4 8.5e-13 47.7 0.4 1.6 1 0 0 1 1 1 1 SAP domain RNase_P_Rpp14 PF01900.19 EOO01539.1 - 2.2e-39 133.8 0.0 2.9e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Tim17 PF02466.19 EOO01540.1 - 1.6e-39 134.7 10.5 2e-39 134.4 10.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ASFV_J13L PF05568.11 EOO01541.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Synaptobrevin PF00957.21 EOO01541.1 - 0.046 13.5 0.3 0.075 12.8 0.3 1.2 1 0 0 1 1 1 0 Synaptobrevin Sigma_reg_N PF13800.6 EOO01541.1 - 0.056 13.7 0.3 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Sensor PF13796.6 EOO01541.1 - 0.077 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative sensor DUF3139 PF11337.8 EOO01541.1 - 0.15 12.7 0.4 0.23 12.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) DUF4307 PF14155.6 EOO01541.1 - 0.23 11.3 3.3 0.14 12.0 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) VirB8 PF04335.13 EOO01541.1 - 0.67 9.8 8.3 1.7 8.5 2.9 2.1 1 1 1 2 2 2 0 VirB8 protein WD40 PF00400.32 EOO01542.1 - 1.3e-13 51.2 0.0 0.0021 18.9 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO01542.1 - 1.6e-05 25.1 0.0 0.092 13.1 0.0 3.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF917 PF06032.12 EOO01543.1 - 4.2e-114 381.0 0.5 9.1e-114 379.9 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 EOO01543.1 - 7.6e-30 104.2 9.1 6.4e-26 91.3 0.9 3.4 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EOO01543.1 - 4.1e-18 65.7 0.5 8.7e-16 58.1 0.4 2.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 EOO01543.1 - 0.00034 19.4 0.9 0.25 9.9 0.0 2.4 2 0 0 2 2 2 2 MutL protein StbA PF06406.11 EOO01543.1 - 0.0015 17.9 0.8 0.27 10.4 0.1 2.6 2 0 0 2 2 2 2 StbA protein BcrAD_BadFG PF01869.20 EOO01543.1 - 0.0031 17.0 2.2 0.2 11.1 0.0 2.9 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Pterin_bind PF00809.22 EOO01543.1 - 0.023 14.4 0.6 7.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Pterin binding enzyme MerR-DNA-bind PF09278.11 EOO01544.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.5 2 0 0 2 2 2 0 MerR, DNA binding Abhydrolase_3 PF07859.13 EOO01545.1 - 2e-15 57.2 0.5 7.7e-13 48.8 0.5 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EOO01545.1 - 1.3e-10 40.7 0.1 2e-09 36.8 0.0 2.4 2 1 0 2 2 2 1 Steryl acetyl hydrolase PDH PF02153.17 EOO01547.1 - 0.053 12.5 0.0 0.092 11.7 0.0 1.4 1 1 0 1 1 1 0 Prephenate dehydrogenase OTU PF02338.19 EOO01549.1 - 6.7e-08 33.1 0.0 1.2e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease UBX PF00789.20 EOO01549.1 - 0.019 15.2 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 UBX domain FOXP-CC PF16159.5 EOO01549.1 - 0.14 12.8 0.7 22 5.8 0.1 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain Lipase_GDSL_2 PF13472.6 EOO01550.1 - 3e-10 40.8 0.0 3.9e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EOO01550.1 - 0.0057 16.6 0.0 0.014 15.3 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.16 EOO01551.1 - 4.4e-28 98.2 25.2 4.4e-28 98.2 25.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2085 PF09858.9 EOO01551.1 - 6.2 7.4 12.8 18 5.9 0.0 3.8 4 0 0 4 4 4 0 Predicted membrane protein (DUF2085) NAD_binding_10 PF13460.6 EOO01552.1 - 3.3e-14 53.2 0.1 6.1e-14 52.3 0.0 1.4 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EOO01552.1 - 4.1e-14 52.7 0.1 5.4e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EOO01552.1 - 1.4e-06 28.6 0.0 2.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EOO01552.1 - 4.2e-05 23.1 0.0 6.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EOO01552.1 - 0.00059 20.0 0.2 0.0015 18.6 0.1 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.23 EOO01552.1 - 0.0016 18.5 0.2 0.0035 17.4 0.2 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 EOO01552.1 - 0.0031 17.0 0.9 0.022 14.2 0.9 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.24 EOO01552.1 - 0.0093 16.4 0.1 0.027 14.9 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EOO01552.1 - 0.0099 16.4 0.3 0.02 15.5 0.3 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 EOO01552.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EOO01552.1 - 0.014 15.3 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 KR domain GFO_IDH_MocA PF01408.22 EOO01552.1 - 0.038 14.8 0.0 0.074 13.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 EOO01552.1 - 0.055 13.5 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EOO01552.1 - 0.1 12.2 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.16 EOO01553.1 - 1.9e-09 37.0 9.9 2.3e-09 36.7 9.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Rop-like PF05082.13 EOO01553.1 - 0.15 11.9 0.7 0.3 10.9 0.7 1.5 1 0 0 1 1 1 0 Rop-like WSC PF01822.19 EOO01554.1 - 3.3e-13 49.6 11.8 8.5e-13 48.3 11.8 1.7 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 EOO01554.1 - 4e-10 38.9 3.8 7.9e-10 38.0 3.8 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF5305 PF17231.2 EOO01554.1 - 0.00012 21.6 0.8 0.00018 21.0 0.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Podoplanin PF05808.11 EOO01554.1 - 0.00051 20.2 2.5 0.001 19.2 2.5 1.4 1 0 0 1 1 1 1 Podoplanin DUF4448 PF14610.6 EOO01554.1 - 0.00055 19.8 0.1 0.00074 19.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4366 PF14283.6 EOO01554.1 - 0.0014 18.7 0.1 0.0022 18.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) MGC-24 PF05283.11 EOO01554.1 - 0.0055 17.2 5.3 0.0055 17.2 5.3 2.0 1 1 2 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Trp_oprn_chp PF09534.10 EOO01554.1 - 0.032 14.0 2.7 0.094 12.5 2.9 1.6 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EphA2_TM PF14575.6 EOO01554.1 - 0.051 14.5 0.0 0.37 11.7 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CbtA PF09490.10 EOO01554.1 - 0.06 13.1 0.3 0.06 13.1 0.3 1.6 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Insulin_TMD PF17870.1 EOO01554.1 - 0.1 12.7 1.5 0.11 12.5 0.1 1.8 2 0 0 2 2 1 0 Insulin receptor trans-membrane segment CD34_antigen PF06365.12 EOO01554.1 - 0.14 11.8 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF2207 PF09972.9 EOO01554.1 - 0.18 10.5 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Nitrate_red_gam PF02665.14 EOO01554.1 - 0.2 11.2 0.2 0.3 10.6 0.2 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Gram_pos_anchor PF00746.21 EOO01554.1 - 0.3 11.1 2.3 1.1 9.3 2.3 2.0 1 1 0 1 1 1 0 LPXTG cell wall anchor motif DUF3042 PF11240.8 EOO01554.1 - 0.54 10.3 2.9 0.34 11.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Sel1 PF08238.12 EOO01555.1 - 2.2e-13 50.4 27.8 1.2e-05 25.8 0.2 7.6 7 0 0 7 7 7 4 Sel1 repeat TPR_1 PF00515.28 EOO01555.1 - 0.0024 17.6 0.4 0.0024 17.6 0.4 3.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EOO01555.1 - 0.03 14.4 0.3 0.03 14.4 0.3 4.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EOO01555.1 - 0.43 11.5 2.4 10 7.2 0.0 3.8 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EOO01555.1 - 1 10.1 0.1 1 10.1 0.1 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EOO01555.1 - 1.7 9.0 8.2 0.84 10.0 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EOO01556.1 - 5.7e-146 487.1 0.0 8.5e-146 486.5 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 EOO01556.1 - 9e-98 327.7 0.0 1.2e-97 327.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EOO01556.1 - 1e-36 124.3 16.4 1.6e-07 31.9 0.2 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO01556.1 - 1.1e-08 35.3 1.0 0.0029 17.9 0.0 5.8 3 2 5 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 EOO01556.1 - 0.051 13.4 0.1 0.53 10.2 0.0 2.3 1 1 0 2 2 2 0 Region in Clathrin and VPS Nup160 PF11715.8 EOO01556.1 - 0.17 10.5 6.4 5.5 5.5 0.0 3.9 2 1 1 4 4 4 0 Nucleoporin Nup120/160 Bromodomain PF00439.25 EOO01558.1 - 2.2e-39 133.4 0.6 3.3e-20 71.9 0.3 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 EOO01558.1 - 2e-20 72.8 1.8 7.3e-20 71.0 1.8 2.0 1 0 0 1 1 1 1 BAH domain AAT PF03417.16 EOO01559.1 - 2e-06 27.7 0.1 4.7e-05 23.2 0.1 2.6 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase MFS_1 PF07690.16 EOO01560.1 - 1e-38 133.2 49.4 1e-38 133.2 49.4 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EOO01560.1 - 1.5e-16 60.0 26.5 2.9e-16 59.0 26.5 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_M43 PF05572.13 EOO01561.1 - 9.6e-14 51.6 0.4 2.1e-13 50.5 0.4 1.5 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EOO01561.1 - 1.1e-05 25.7 0.4 2.4e-05 24.6 0.4 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EOO01561.1 - 0.0027 18.2 0.1 0.0089 16.5 0.0 1.9 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EOO01561.1 - 0.023 14.6 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like NYN PF01936.18 EOO01562.1 - 0.029 14.9 0.0 0.085 13.3 0.0 1.9 1 1 0 1 1 1 0 NYN domain EI24 PF07264.11 EOO01563.1 - 1.9e-15 57.6 6.4 4.3e-13 49.9 6.4 2.1 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FmdA_AmdA PF03069.15 EOO01564.1 - 2e-155 517.2 0.0 2.6e-155 516.9 0.0 1.1 1 0 0 1 1 1 1 Acetamidase/Formamidase family Importin_rep_4 PF18808.1 EOO01565.1 - 5.6e-33 113.1 13.4 7.8e-33 112.6 1.5 5.0 5 1 1 6 6 5 1 Importin repeat Importin_rep_5 PF18816.1 EOO01565.1 - 7.2e-20 71.0 6.0 9.1e-20 70.7 0.3 3.9 5 0 0 5 5 4 1 Importin repeat HEAT_2 PF13646.6 EOO01565.1 - 3.6e-16 59.3 8.1 6e-08 33.0 0.1 7.4 4 2 2 6 6 6 2 HEAT repeats HEAT PF02985.22 EOO01565.1 - 1.8e-15 55.7 9.7 0.0038 17.4 0.0 9.2 10 0 0 10 10 8 3 HEAT repeat HEAT_EZ PF13513.6 EOO01565.1 - 1.5e-14 54.1 13.7 4.3e-06 27.1 0.1 8.6 7 1 2 9 9 8 4 HEAT-like repeat Importin_rep_6 PF18829.1 EOO01565.1 - 5.2e-12 45.9 3.0 2.3e-11 43.7 0.2 3.3 3 0 0 3 3 3 1 Importin repeat 6 RIX1 PF08167.12 EOO01565.1 - 1.7e-10 41.0 0.0 2.6e-06 27.3 0.0 4.2 3 1 1 4 4 4 3 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 EOO01565.1 - 1.7e-10 41.3 0.6 0.0014 19.2 0.0 7.6 7 2 4 11 11 9 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EOO01565.1 - 5.2e-09 36.3 3.7 0.028 14.4 0.0 6.0 5 4 0 6 6 4 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EOO01565.1 - 3e-08 33.2 0.6 1.9e-05 24.0 0.0 3.3 2 0 0 2 2 2 2 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 EOO01565.1 - 3.4e-08 33.6 0.1 0.0025 17.7 0.0 5.4 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 EOO01565.1 - 1.5e-07 31.2 0.1 0.0055 16.3 0.1 5.7 5 1 1 6 6 6 1 CLASP N terminal DRIM PF07539.12 EOO01565.1 - 4.6e-07 28.6 0.4 0.00065 18.1 0.4 4.4 3 2 2 5 5 5 1 Down-regulated in metastasis DUF3535 PF12054.8 EOO01565.1 - 4.7e-05 22.8 0.4 0.00022 20.6 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) Arm PF00514.23 EOO01565.1 - 8.6e-05 22.4 5.4 0.2 11.8 0.1 5.2 5 0 0 5 5 4 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EOO01565.1 - 0.0011 17.7 1.5 0.075 11.6 0.3 3.4 2 1 1 4 4 4 2 Adaptin N terminal region UNC45-central PF11701.8 EOO01565.1 - 0.0014 18.6 3.0 0.57 10.1 0.2 3.2 3 0 0 3 3 3 2 Myosin-binding striated muscle assembly central Telomere_reg-2 PF10193.9 EOO01565.1 - 0.0039 17.6 5.4 0.015 15.7 1.9 3.3 2 1 0 2 2 2 1 Telomere length regulation protein CAS_CSE1 PF03378.15 EOO01565.1 - 0.0059 15.2 0.5 3.1 6.2 0.1 3.6 2 1 2 4 4 4 1 CAS/CSE protein, C-terminus RTP1_C1 PF10363.9 EOO01565.1 - 0.0064 16.7 1.0 0.18 12.0 0.3 3.7 2 1 1 3 3 2 1 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_N PF03224.14 EOO01565.1 - 0.012 15.0 5.9 0.36 10.1 0.2 3.6 2 2 0 3 3 3 0 V-ATPase subunit H Cnd3 PF12719.7 EOO01565.1 - 0.022 13.9 0.0 0.21 10.7 0.0 2.6 1 1 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain IBN_N PF03810.19 EOO01565.1 - 0.024 14.5 0.2 0.35 10.8 0.0 3.1 3 0 0 3 3 3 0 Importin-beta N-terminal domain HrcA_DNA-bdg PF03444.15 EOO01565.1 - 0.041 13.5 1.5 55 3.5 0.0 3.9 4 0 0 4 4 3 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding MMS19_N PF14500.6 EOO01565.1 - 0.044 13.4 2.2 11 5.5 0.1 3.8 5 0 0 5 5 4 0 Dos2-interacting transcription regulator of RNA-Pol-II TFCD_C PF12612.8 EOO01565.1 - 0.082 12.7 0.0 1.1 9.0 0.0 2.8 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal Dopey_N PF04118.14 EOO01565.1 - 0.82 8.7 3.8 1 8.4 0.1 2.9 4 1 1 5 5 5 0 Dopey, N-terminal DUF3361 PF11841.8 EOO01565.1 - 0.93 9.4 3.0 52 3.8 0.1 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF3361) Ammonium_transp PF00909.21 EOO01566.1 - 2.6e-112 375.4 20.9 3e-112 375.2 20.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family HIP1_clath_bdg PF16515.5 EOO01567.1 - 0.00099 19.7 20.2 0.024 15.2 9.1 2.8 2 1 1 3 3 3 2 Clathrin-binding domain of Huntingtin-interacting protein 1 Ax_dynein_light PF10211.9 EOO01567.1 - 0.0011 18.9 9.6 0.0011 18.9 9.6 2.2 2 0 0 2 2 2 1 Axonemal dynein light chain CENP-F_leu_zip PF10473.9 EOO01567.1 - 0.0013 18.7 4.8 0.0013 18.7 4.8 2.5 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4795 PF16043.5 EOO01567.1 - 0.0014 18.3 19.5 0.13 11.8 8.6 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) DUF2935 PF11155.8 EOO01567.1 - 0.0037 17.6 0.7 1.8 8.9 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF2935) Mito_fiss_reg PF05308.11 EOO01567.1 - 0.0044 17.2 8.8 0.0044 17.2 8.8 1.4 2 0 0 2 2 1 1 Mitochondrial fission regulator DUF4407 PF14362.6 EOO01567.1 - 0.0044 16.4 11.0 0.0044 16.4 11.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 EOO01567.1 - 0.0073 16.4 6.3 0.043 13.9 1.5 2.6 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 EOO01567.1 - 0.014 14.7 5.3 0.014 14.7 5.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) IFT57 PF10498.9 EOO01567.1 - 0.018 14.0 20.6 0.21 10.5 9.3 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Fez1 PF06818.15 EOO01567.1 - 0.019 15.4 23.0 0.024 15.1 23.0 1.1 1 0 0 1 1 1 0 Fez1 ADIP PF11559.8 EOO01567.1 - 0.03 14.4 23.3 0.35 10.9 8.8 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding KASH_CCD PF14662.6 EOO01567.1 - 0.049 13.5 22.8 0.078 12.8 10.7 2.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 EOO01567.1 - 0.061 12.7 25.2 0.27 10.5 4.4 2.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 EOO01567.1 - 0.071 13.3 14.0 0.31 11.2 3.3 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 EOO01567.1 - 0.075 13.1 27.1 0.21 11.7 8.4 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 EOO01567.1 - 0.083 13.1 10.6 0.34 11.2 0.4 4.2 3 1 1 4 4 4 0 Homeobox associated leucine zipper Phage_GP20 PF06810.11 EOO01567.1 - 0.1 12.4 22.4 0.75 9.6 6.8 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 GrpE PF01025.19 EOO01567.1 - 0.15 11.7 24.8 0.29 10.8 4.8 2.8 1 1 1 2 2 2 0 GrpE APG6_N PF17675.1 EOO01567.1 - 0.16 12.5 33.4 0.65 10.5 14.2 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region TolA_bind_tri PF16331.5 EOO01567.1 - 0.17 12.0 17.3 1.7 8.8 5.6 3.4 1 1 2 3 3 3 0 TolA binding protein trimerisation TMF_TATA_bd PF12325.8 EOO01567.1 - 0.17 12.1 25.7 0.057 13.7 15.1 2.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 EOO01567.1 - 0.18 10.7 26.0 4.9 5.9 24.5 2.4 1 1 0 1 1 1 0 Spc7 kinetochore protein ZapB PF06005.12 EOO01567.1 - 0.2 12.1 27.1 38 4.8 3.1 3.8 1 1 1 2 2 1 0 Cell division protein ZapB DUF2746 PF10874.8 EOO01567.1 - 0.21 12.1 2.6 0.53 10.7 0.5 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2746) bZIP_1 PF00170.21 EOO01567.1 - 0.36 10.9 21.5 0.64 10.2 1.8 4.6 1 1 3 4 4 4 0 bZIP transcription factor DUF5395 PF17373.2 EOO01567.1 - 0.66 10.7 3.3 1.3 9.7 0.2 2.6 2 2 0 2 2 2 0 Family of unknown function (DUF5395) ATG16 PF08614.11 EOO01567.1 - 0.72 10.1 26.4 3.7 7.7 13.3 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 EOO01567.1 - 0.73 10.3 11.9 10 6.6 0.7 4.0 2 2 3 5 5 5 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.8 EOO01567.1 - 0.73 7.3 23.3 1.4 6.4 23.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Prominin PF05478.11 EOO01567.1 - 0.74 7.7 6.1 0.83 7.5 6.1 1.1 1 0 0 1 1 1 0 Prominin DivIC PF04977.15 EOO01567.1 - 1.3 8.9 26.2 1.1 9.1 3.7 4.8 1 1 3 5 5 5 0 Septum formation initiator DUF1664 PF07889.12 EOO01567.1 - 2.1 8.4 12.4 12 6.0 8.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 EOO01567.1 - 2.1 8.5 26.8 1.7 8.8 13.1 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 PKcGMP_CC PF16808.5 EOO01567.1 - 2.9 7.8 20.0 0.99 9.3 3.9 4.1 3 2 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TACC_C PF05010.14 EOO01567.1 - 2.9 7.6 23.8 2.4 7.9 9.1 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF2968 PF11180.8 EOO01567.1 - 3 7.5 16.3 1.6 8.4 12.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) YabA PF06156.13 EOO01567.1 - 3.7 8.2 19.6 16 6.2 1.5 3.2 1 1 0 2 2 2 0 Initiation control protein YabA Fzo_mitofusin PF04799.13 EOO01567.1 - 4.8 6.7 14.0 2.3 7.8 4.9 2.9 1 1 1 2 2 2 0 fzo-like conserved region Cauli_DNA-bind PF03310.13 EOO01567.1 - 5.6 7.0 8.3 1.9 8.6 4.4 1.9 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein DUF724 PF05266.14 EOO01567.1 - 6 6.6 22.1 22 4.8 6.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 EOO01567.1 - 7.3 6.6 24.9 83 3.2 24.9 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 EOO01567.1 - 9.5 5.7 15.6 14 5.2 15.6 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit adh_short PF00106.25 EOO01569.1 - 6.3e-21 74.7 0.1 7.7e-21 74.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO01569.1 - 5.4e-13 49.0 0.0 6.6e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO01569.1 - 9.1e-13 48.5 0.6 1.2e-12 48.1 0.6 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 EOO01569.1 - 0.12 12.4 0.4 0.2 11.7 0.3 1.4 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_11 PF00457.17 EOO01570.1 - 6.2e-80 267.0 21.4 7.1e-80 266.8 21.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CarboxypepD_reg PF13620.6 EOO01570.1 - 2.6 8.4 9.2 5.1 7.4 0.4 3.2 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain CSN8_PSD8_EIF3K PF10075.9 EOO01571.1 - 3.7e-19 69.1 0.0 6.4e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family GPI-anchored PF10342.9 EOO01572.1 - 7e-07 29.9 0.0 9.3e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_transf_24 PF18404.1 EOO01574.1 - 2.1e-147 489.7 2.7 3.1e-147 489.1 2.7 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EOO01574.1 - 2.4e-69 234.1 0.0 2.9e-67 227.3 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 EOO01574.1 - 3.8e-57 193.6 0.4 1.4e-56 191.8 0.2 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EOO01574.1 - 6.8e-48 162.0 0.4 1.3e-46 157.8 0.2 3.2 3 1 1 4 4 4 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EOO01574.1 - 7.2e-40 135.5 0.0 1.5e-39 134.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_12 PF18400.1 EOO01574.1 - 3.2e-28 98.9 0.1 8.2e-28 97.6 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EOO01574.1 - 0.001 18.7 0.1 0.0024 17.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 Cofilin_ADF PF00241.20 EOO01575.1 - 4.5e-25 87.8 0.1 5e-25 87.7 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Rad54_N PF08658.10 EOO01576.1 - 5.1e-59 199.5 4.8 2.2e-58 197.4 3.9 2.1 2 0 0 2 2 2 1 Rad54 N terminal SNF2_N PF00176.23 EOO01576.1 - 6.5e-59 199.4 0.0 1.5e-58 198.2 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EOO01576.1 - 1.1e-15 57.9 0.0 3.2e-15 56.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO01576.1 - 6.6e-09 36.0 0.0 1.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EOO01576.1 - 0.0015 17.8 0.0 0.0066 15.7 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Citrate_ly_lig PF08218.11 EOO01576.1 - 0.012 15.3 0.0 0.035 13.8 0.0 1.7 2 0 0 2 2 2 0 Citrate lyase ligase C-terminal domain SWI2_SNF2 PF18766.1 EOO01576.1 - 0.079 12.6 0.0 0.21 11.2 0.0 1.7 1 1 0 1 1 1 0 SWI2/SNF2 ATPase CBS PF00571.28 EOO01577.1 - 1.5e-17 63.8 2.1 5.9e-05 23.4 0.0 5.1 4 1 1 5 5 5 3 CBS domain Pectinesterase PF01095.19 EOO01578.1 - 9.2e-41 139.5 7.5 9.2e-41 139.5 7.5 2.4 2 0 0 2 2 2 1 Pectinesterase Gcd10p PF04189.13 EOO01579.1 - 1.3e-112 375.8 0.0 1.6e-112 375.5 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family Pyr_redox_2 PF07992.14 EOO01581.1 - 1e-32 113.6 0.0 1.5e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EOO01581.1 - 9e-12 45.4 0.4 9.8e-09 35.7 0.3 3.2 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EOO01581.1 - 0.0089 16.0 5.9 1.1 9.2 0.0 3.9 4 1 0 4 4 4 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EOO01581.1 - 0.023 13.6 3.9 1.9 7.2 0.0 2.6 2 1 1 3 3 3 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 EOO01581.1 - 0.047 12.9 8.9 0.22 10.7 0.0 3.2 2 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S9 PF00326.21 EOO01581.1 - 0.077 12.5 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family K_oxygenase PF13434.6 EOO01581.1 - 0.081 12.1 0.0 0.19 10.8 0.0 1.6 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EOO01581.1 - 0.081 12.5 8.2 4.2 6.8 0.0 4.0 3 1 1 4 4 4 0 FAD dependent oxidoreductase GIDA PF01134.22 EOO01581.1 - 0.13 11.3 3.5 1.2 8.2 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A DUF4233 PF14017.6 EOO01582.1 - 5.7 7.3 9.7 0.16 12.3 3.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) AltA1 PF16541.5 EOO01583.1 - 7.1e-31 107.3 0.4 1.1e-30 106.8 0.4 1.3 1 0 0 1 1 1 1 Alternaria alternata allergen 1 DJ-1_PfpI PF01965.24 EOO01584.1 - 2.3e-09 37.2 0.0 3.1e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Glyco_hydro_3_C PF01915.22 EOO01585.1 - 1.6e-58 198.0 0.0 7e-58 195.9 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EOO01585.1 - 4.2e-28 98.7 0.0 7e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EOO01585.1 - 2.7e-20 72.2 0.2 7e-20 70.9 0.2 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EOO01585.1 - 1e-06 28.7 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Exo_endo_phos PF03372.23 EOO01586.1 - 9.5e-10 38.4 0.1 1.4e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Myosin_N PF02736.19 EOO01586.1 - 0.025 14.4 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain P21-Arc PF04062.14 EOO01588.1 - 9.2e-43 146.3 0.0 1e-42 146.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit NmrA PF05368.13 EOO01589.1 - 3.4e-22 79.2 0.0 4.9e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO01589.1 - 4.5e-16 59.3 0.1 1.2e-15 57.9 0.0 1.9 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EOO01589.1 - 0.0019 17.7 0.4 0.0071 15.8 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EOO01589.1 - 0.058 12.8 0.7 0.11 11.9 0.7 1.5 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 EOO01589.1 - 0.083 11.9 0.1 0.18 10.8 0.1 1.6 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Spore_Cse60 PF10957.8 EOO01589.1 - 0.22 11.5 0.9 0.45 10.6 0.1 1.9 2 0 0 2 2 2 0 Sporulation protein Cse60 Tyrosinase PF00264.20 EOO01590.1 - 4.5e-22 79.4 0.8 5.8e-21 75.8 0.8 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase GF_recep_IV PF14843.6 EOO01590.1 - 0.058 13.2 0.1 0.097 12.5 0.1 1.2 1 0 0 1 1 1 0 Growth factor receptor domain IV AIRS PF00586.24 EOO01590.1 - 0.065 13.9 0.0 0.64 10.7 0.0 2.3 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain Paf67 PF10255.9 EOO01591.1 - 1.8e-156 521.2 0.2 2.2e-156 521.0 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 EOO01591.1 - 0.031 14.4 0.0 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EOO01591.1 - 0.084 12.7 0.1 0.96 9.4 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat End_beta_barrel PF12195.8 EOO01591.1 - 0.09 12.7 0.0 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase adh_short_C2 PF13561.6 EOO01592.1 - 1.7e-52 178.4 0.1 1.9e-52 178.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO01592.1 - 4.4e-39 134.0 0.0 5.8e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO01592.1 - 7.7e-09 35.7 0.0 1.1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 KR domain PEP_hydrolase PF09370.10 EOO01592.1 - 0.076 12.2 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like Usp PF00582.26 EOO01593.1 - 4.9e-15 56.3 0.3 2e-14 54.3 0.0 2.1 2 0 0 2 2 2 1 Universal stress protein family HeLo PF14479.6 EOO01594.1 - 1.3e-43 149.3 0.1 1.7e-43 148.8 0.1 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation HET-s_218-289 PF11558.8 EOO01594.1 - 5.4e-25 87.2 0.9 1.3e-24 86.0 0.9 1.7 1 0 0 1 1 1 1 Het-s 218-289 HET-S PF17108.5 EOO01594.1 - 0.0046 16.6 0.5 0.31 10.8 0.1 2.3 2 0 0 2 2 2 2 N-terminal small S protein of HET, non-prionic Ank_2 PF12796.7 EOO01595.1 - 1.9e-28 98.8 0.0 1.2e-08 35.4 0.0 5.9 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EOO01595.1 - 3.1e-26 91.4 1.5 1.8e-07 31.6 0.0 7.5 6 1 1 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EOO01595.1 - 5e-19 66.4 0.3 0.049 14.2 0.0 9.2 10 0 0 10 10 10 4 Ankyrin repeat Ank_5 PF13857.6 EOO01595.1 - 6.5e-18 64.6 2.5 2.9e-10 40.2 0.2 7.0 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 EOO01595.1 - 1.6e-14 53.6 10.4 0.00048 20.4 0.0 8.2 9 1 0 9 9 9 5 Ankyrin repeat Fe-ADH PF00465.19 EOO01596.1 - 3.7e-103 345.1 0.2 3.7e-103 345.1 0.2 1.7 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Aldedh PF00171.22 EOO01596.1 - 3.8e-25 88.3 8.8 1.3e-24 86.5 8.7 1.6 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Fe-ADH_2 PF13685.6 EOO01596.1 - 1.8e-16 60.6 0.9 2.4e-07 30.7 0.0 2.8 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Tsi6 PF18660.1 EOO01596.1 - 0.051 13.6 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Tsi6 T6SS_VipA PF05591.12 EOO01596.1 - 0.16 11.8 0.2 0.34 10.7 0.2 1.5 1 0 0 1 1 1 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 Fmp27 PF10344.9 EOO01598.1 - 2.6e-244 813.3 0.0 5.5e-244 812.3 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 EOO01598.1 - 1.8e-206 686.6 0.1 1.8e-206 686.6 0.1 3.2 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 EOO01598.1 - 2.6e-193 643.3 0.3 4.5e-193 642.5 0.3 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 EOO01598.1 - 1.1e-56 191.3 0.0 2.9e-56 189.9 0.0 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EOO01598.1 - 7.5e-54 181.8 0.5 1.7e-53 180.7 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EOO01598.1 - 3.2e-35 120.9 0.2 2.4e-34 118.1 0.1 2.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain MFS_1 PF07690.16 EOO01599.1 - 3e-05 23.1 12.2 7.4e-05 21.8 12.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Aa_trans PF01490.18 EOO01599.1 - 0.011 14.5 1.1 0.012 14.4 0.2 1.4 2 0 0 2 2 2 0 Transmembrane amino acid transporter protein MFS_1_like PF12832.7 EOO01599.1 - 0.43 9.4 6.2 0.12 11.2 3.2 1.5 2 0 0 2 2 2 0 MFS_1 like family DUF1304 PF06993.12 EOO01599.1 - 1.4 8.9 6.8 0.22 11.5 1.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1304) PEX11 PF05648.14 EOO01600.1 - 9.8e-05 21.9 2.0 0.015 14.8 0.0 2.7 3 0 0 3 3 3 2 Peroxisomal biogenesis factor 11 (PEX11) Oxidored_FMN PF00724.20 EOO01601.1 - 1.4e-87 294.2 0.0 1.6e-87 293.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Flu_B_M2 PF04772.12 EOO01601.1 - 0.21 11.9 0.0 0.38 11.0 0.0 1.3 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) DJ-1_PfpI PF01965.24 EOO01602.1 - 1e-07 31.9 0.0 2.4e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family RRM_1 PF00076.22 EOO01603.1 - 6.2e-13 48.4 0.0 1.1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1939 PF09154.10 EOO01603.1 - 0.11 12.7 0.1 2.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1939) KdpC PF02669.15 EOO01603.1 - 0.61 9.9 2.4 0.51 10.2 0.9 1.6 1 1 1 2 2 2 0 K+-transporting ATPase, c chain Asp-B-Hydro_N PF05279.11 EOO01603.1 - 5.2 7.1 19.5 8.4 6.4 19.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region NACHT PF05729.12 EOO01604.1 - 1.5e-10 41.2 0.0 2.2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EOO01604.1 - 6.6e-05 23.4 0.0 0.00015 22.2 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EOO01604.1 - 0.00014 22.1 0.0 0.00028 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EOO01604.1 - 0.0023 17.3 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 KaiC Antimicrobial22 PF16047.5 EOO01604.1 - 0.01 15.7 0.2 0.023 14.5 0.2 1.6 1 0 0 1 1 1 0 Frog antimicrobial peptide RNA_helicase PF00910.22 EOO01604.1 - 0.012 16.0 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 EOO01604.1 - 0.013 14.8 0.2 1.1 8.4 0.1 2.3 1 1 1 2 2 2 0 KAP family P-loop domain AAA PF00004.29 EOO01604.1 - 0.013 15.9 0.0 0.034 14.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EOO01604.1 - 0.024 14.7 0.0 1.2 9.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF3013 PF11217.8 EOO01604.1 - 0.085 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3013) NTPase_1 PF03266.15 EOO01604.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.6 1 1 0 1 1 1 0 NTPase DUF2075 PF09848.9 EOO01604.1 - 0.15 11.3 0.0 0.33 10.1 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) F-box PF00646.33 EOO01605.1 - 3.6e-07 29.9 2.6 6.6e-07 29.1 2.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EOO01605.1 - 5.7e-06 26.1 2.1 1.1e-05 25.2 2.1 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EOO01605.1 - 0.0015 18.4 0.4 0.0015 18.4 0.4 2.3 3 0 0 3 3 3 1 F-box ABA_GPCR PF12430.8 EOO01607.1 - 1.3e-57 194.5 2.1 1.3e-57 194.5 0.4 1.9 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 EOO01607.1 - 5.7e-24 84.0 0.6 4.4e-23 81.1 0.0 2.6 3 0 0 3 3 3 1 The Golgi pH Regulator (GPHR) Family N-terminal NYN PF01936.18 EOO01608.1 - 3.3e-32 112.0 0.0 6.7e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 EOO01608.1 - 5.6e-14 51.7 0.0 1.4e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Arginase PF00491.21 EOO01608.1 - 6.1e-06 25.9 0.0 9.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Arginase family Tetrabrachion PF11401.8 EOO01609.1 - 0.019 15.0 0.1 0.035 14.1 0.1 1.4 1 0 0 1 1 1 0 Tetrabrachion Amidohydro_3 PF07969.11 EOO01610.1 - 9.7e-68 229.7 0.8 1.1e-67 229.5 0.8 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EOO01610.1 - 5.8e-14 52.2 0.1 1.6e-09 37.6 0.0 2.8 3 1 0 3 3 3 2 Amidohydrolase family Oxidored_FMN PF00724.20 EOO01611.1 - 1.5e-91 307.2 0.0 1.7e-91 307.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 EOO01611.1 - 0.24 11.1 0.0 0.38 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) GTP_EFTU PF00009.27 EOO01612.1 - 1.8e-58 197.3 0.0 2.9e-58 196.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EOO01612.1 - 1.7e-16 60.0 0.0 5.7e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EOO01612.1 - 8.2e-09 35.7 0.0 2.4e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EOO01612.1 - 6.2e-06 26.2 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EOO01612.1 - 0.0014 18.4 0.0 0.019 14.7 0.0 2.7 2 1 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 EOO01612.1 - 0.029 14.5 0.0 0.079 13.0 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase UBX PF00789.20 EOO01613.1 - 3.1e-13 49.7 0.0 5.4e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain SelK_SelG PF10961.8 EOO01613.1 - 0.006 17.2 0.1 0.018 15.7 0.1 1.8 1 0 0 1 1 1 1 Selenoprotein SelK_SelG PCI PF01399.27 EOO01614.1 - 1.5e-19 70.4 0.1 3.6e-18 66.0 0.0 2.5 2 0 0 2 2 2 1 PCI domain TPR_12 PF13424.6 EOO01614.1 - 0.004 17.4 1.5 2 8.8 0.1 4.0 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EOO01614.1 - 0.033 14.0 1.3 0.34 10.8 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EOO01614.1 - 0.038 14.0 1.3 1.7 8.9 0.1 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EOO01614.1 - 0.057 13.6 6.4 0.2 11.8 0.3 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Gp5_OB PF06714.11 EOO01616.1 - 0.031 14.5 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 Gp5 N-terminal OB domain TraL PF07178.11 EOO01616.1 - 0.25 11.8 1.4 0.49 10.9 1.4 1.4 1 0 0 1 1 1 0 TraL protein FAD-oxidase_C PF02913.19 EOO01618.1 - 4.9e-59 200.0 0.0 5.9e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EOO01618.1 - 2.1e-18 66.4 0.0 4.5e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Cu-oxidase_3 PF07732.15 EOO01619.1 - 1.2e-46 157.6 8.4 1.1e-43 148.0 0.9 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EOO01619.1 - 1.7e-34 118.5 11.7 3.2e-33 114.4 2.6 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EOO01619.1 - 3.6e-29 101.9 0.0 1.1e-28 100.4 0.0 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cupredoxin_1 PF13473.6 EOO01619.1 - 0.13 12.4 0.0 7.2 6.8 0.0 3.1 3 0 0 3 3 3 0 Cupredoxin-like domain AhpC-TSA_2 PF13911.6 EOO01620.1 - 7.2e-08 32.6 0.1 1.5e-07 31.5 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EOO01620.1 - 4.4e-06 26.6 0.0 8.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EOO01620.1 - 0.00029 20.6 0.0 0.00048 19.9 0.0 1.3 1 0 0 1 1 1 1 Redoxin EGF_2 PF07974.13 EOO01621.1 - 1.1 9.6 11.6 2.1 8.8 11.6 1.5 1 0 0 1 1 1 0 EGF-like domain Ribosomal_L24e PF01246.20 EOO01622.1 - 3.9e-28 97.5 0.1 3.9e-28 97.5 0.1 1.9 2 1 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.12 EOO01622.1 - 0.14 11.7 2.5 0.18 11.3 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Methyltransf_2 PF00891.18 EOO01623.1 - 1.3e-22 80.1 0.0 2.2e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 EOO01623.1 - 0.025 14.4 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.12 EOO01623.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase RE_TaqI PF09573.10 EOO01623.1 - 0.24 11.2 1.0 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 TaqI restriction endonuclease CytochromB561_N PF09786.9 EOO01623.1 - 0.27 10.2 3.2 0.37 9.7 3.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal MPC PF03650.13 EOO01624.1 - 4.3e-48 162.0 1.0 7.2e-48 161.3 1.0 1.3 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers CBP4 PF07960.11 EOO01625.1 - 7.5e-30 103.4 0.5 1.1e-29 102.9 0.5 1.2 1 0 0 1 1 1 1 CBP4 SET PF00856.28 EOO01626.1 - 2.8e-12 47.3 0.0 6.4e-12 46.2 0.0 1.6 2 0 0 2 2 2 1 SET domain Redoxin PF08534.10 EOO01627.1 - 1.9e-33 115.2 0.2 2.2e-33 115.1 0.2 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EOO01627.1 - 8.9e-11 41.8 0.0 1.1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Ras PF00071.22 EOO01629.1 - 2.7e-52 176.6 0.0 3.4e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EOO01629.1 - 8.4e-19 68.0 0.0 1.3e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EOO01629.1 - 1.5e-09 37.5 0.0 2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EOO01629.1 - 2.6e-06 27.4 0.0 0.0055 16.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EOO01629.1 - 2.1e-05 24.2 0.1 0.00022 20.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EOO01629.1 - 0.00084 19.4 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NB-ARC PF00931.22 EOO01629.1 - 0.042 13.0 0.0 0.094 11.9 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.6 EOO01629.1 - 0.15 12.3 0.0 0.57 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain L51_S25_CI-B8 PF05047.16 EOO01630.1 - 2.1e-14 53.2 0.0 2.6e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain CaM_binding PF07839.11 EOO01630.1 - 0.00063 20.5 0.0 0.00071 20.3 0.0 1.1 1 0 0 1 1 1 1 Plant calmodulin-binding domain Methyltransf_32 PF13679.6 EOO01631.1 - 0.0059 16.6 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_M23_N PF18421.1 EOO01631.1 - 0.028 14.3 0.0 16 5.5 0.0 3.3 3 0 0 3 3 3 0 Peptidase family M23 N-terminal domain FtsJ PF01728.19 EOO01631.1 - 0.039 14.1 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 EOO01631.1 - 0.093 13.4 0.0 0.29 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 EOO01631.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MTS PF05175.14 EOO01631.1 - 0.17 11.4 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain GidB PF02527.15 EOO01631.1 - 0.18 11.1 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G IGF2_C PF08365.11 EOO01632.1 - 0.043 13.8 2.7 0.14 12.2 2.7 1.9 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide SLC35F PF06027.12 EOO01633.1 - 2.9e-98 329.1 19.8 3.7e-98 328.8 19.8 1.1 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EOO01633.1 - 5.3e-10 38.8 3.3 5.3e-10 38.8 3.3 1.5 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EOO01633.1 - 5e-06 26.7 33.9 9.6e-05 22.6 13.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family FUSC-like PF12805.7 EOO01633.1 - 0.68 9.0 6.4 0.26 10.4 0.5 2.4 2 1 0 2 2 2 0 FUSC-like inner membrane protein yccS eIF-5a PF01287.20 EOO01634.1 - 1.2e-05 25.3 0.0 2.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RCR PF12273.8 EOO01634.1 - 6.9 7.4 9.4 2 9.1 1.2 2.6 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red SesA PF17107.5 EOO01635.1 - 1.8e-16 60.4 1.3 1.8e-16 60.4 1.3 2.1 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Cob_adeno_trans PF01923.18 EOO01635.1 - 0.03 14.5 6.6 0.045 13.9 0.4 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF883 PF05957.13 EOO01635.1 - 0.21 12.2 7.5 0.22 12.1 1.3 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Spc7 PF08317.11 EOO01635.1 - 0.65 8.8 19.0 2.9 6.7 15.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF5358 PF17311.2 EOO01635.1 - 0.84 9.6 6.7 0.39 10.7 0.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5358) TMPIT PF07851.13 EOO01635.1 - 1.6 7.9 15.3 2.3 7.4 3.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein TssO PF17561.2 EOO01635.1 - 2.2 8.4 9.5 4.6 7.4 2.0 2.5 1 1 1 2 2 2 0 Type VI secretion system, TssO YtxH PF12732.7 EOO01635.1 - 7.1 7.2 11.1 12 6.6 4.4 2.8 2 1 0 2 2 2 0 YtxH-like protein CENP-T_C PF15511.6 EOO01636.1 - 1e-47 160.7 0.0 1.7e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EOO01636.1 - 3.8e-09 36.8 0.0 6.7e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 EOO01636.1 - 1.5e-05 25.4 0.3 3.9e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EOO01636.1 - 0.025 14.8 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mem_trans PF03547.18 EOO01637.1 - 1.3e-19 69.9 0.8 6.9e-19 67.5 0.8 1.9 1 1 0 1 1 1 1 Membrane transport protein DUF2076 PF09849.9 EOO01638.1 - 2.4e-08 34.3 11.6 4.4e-08 33.5 11.6 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EOO01638.1 - 5.4e-06 26.4 3.7 8.4e-06 25.8 3.7 1.3 1 0 0 1 1 1 1 CHCH domain Trypan_glycop_C PF10659.9 EOO01638.1 - 0.025 14.9 3.1 0.037 14.4 3.1 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain COX17 PF05051.13 EOO01638.1 - 0.23 11.9 1.8 0.28 11.6 0.3 1.8 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Bindin PF02084.15 EOO01638.1 - 0.28 11.4 4.4 0.33 11.2 4.4 1.1 1 0 0 1 1 1 0 Bindin DUF5132 PF17195.4 EOO01639.1 - 0.016 15.3 0.1 0.042 14.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) DUF2254 PF10011.9 EOO01639.1 - 0.14 10.9 0.5 0.38 9.5 0.0 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) PQ-loop PF04193.14 EOO01639.1 - 0.2 11.5 3.8 0.16 11.8 0.9 2.1 1 1 1 2 2 2 0 PQ loop repeat UPF0542 PF15086.6 EOO01639.1 - 0.46 10.5 0.1 0.46 10.5 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Pkinase PF00069.25 EOO01640.1 - 1.6e-57 194.9 0.0 7.1e-55 186.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EOO01640.1 - 5.9e-33 114.2 0.0 9.5e-32 110.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EOO01640.1 - 7.5e-05 22.2 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EOO01640.1 - 0.0012 17.8 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EOO01640.1 - 0.0017 17.5 0.1 0.0026 16.9 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EOO01640.1 - 0.012 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EOO01640.1 - 0.072 13.0 0.1 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family SUR7 PF06687.12 EOO01641.1 - 2.8e-34 118.6 11.6 3.5e-34 118.3 11.6 1.0 1 0 0 1 1 1 1 SUR7/PalI family Amastin PF07344.11 EOO01641.1 - 0.0093 15.8 9.2 0.0093 15.8 9.2 1.8 2 0 0 2 2 2 1 Amastin surface glycoprotein Cadherin_C_2 PF16492.5 EOO01641.1 - 1.4 9.7 3.8 11 6.8 0.2 3.1 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal DUF373 PF04123.13 EOO01641.1 - 1.5 8.2 4.4 0.32 10.4 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Clc-like PF07062.12 EOO01641.1 - 4.9 6.6 9.4 0.45 9.9 4.9 1.5 2 0 0 2 2 2 0 Clc-like Erf4 PF10256.9 EOO01642.1 - 0.14 12.3 0.0 0.62 10.2 0.0 1.9 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Glycos_transf_4 PF00953.21 EOO01642.1 - 0.19 11.7 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 4 MFS_1 PF07690.16 EOO01643.1 - 7.9e-20 71.1 45.4 7.9e-20 71.1 45.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Prominin PF05478.11 EOO01643.1 - 0.92 7.4 4.3 1.4 6.7 3.0 1.9 2 0 0 2 2 2 0 Prominin DUF2530 PF10745.9 EOO01643.1 - 7.4 6.9 8.5 5.4 7.3 0.5 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2530) AAA_12 PF13087.6 EOO01644.1 - 1.3e-18 67.3 0.0 2.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EOO01644.1 - 1.4e-12 47.9 0.0 1.1e-11 45.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EOO01644.1 - 1.7e-06 27.9 0.2 0.0074 16.1 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EOO01644.1 - 0.0018 18.1 0.0 0.004 17.0 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain MIT PF04212.18 EOO01644.1 - 0.019 15.0 0.0 0.057 13.5 0.0 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain AAA_30 PF13604.6 EOO01644.1 - 0.035 13.8 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain UvrD_C PF13361.6 EOO01644.1 - 0.099 12.0 0.1 0.55 9.5 0.0 2.1 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Beta-Casp PF10996.8 EOO01644.1 - 0.11 12.8 0.0 0.53 10.6 0.0 2.2 2 0 0 2 2 2 0 Beta-Casp domain RRM_1 PF00076.22 EOO01645.1 - 1.5e-10 40.7 0.0 4.2e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAC PF01849.18 EOO01646.1 - 1.3e-23 82.7 0.2 1.9e-23 82.2 0.2 1.3 1 0 0 1 1 1 1 NAC domain Coq4 PF05019.13 EOO01647.1 - 5.4e-84 280.9 0.0 6.9e-84 280.6 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 PAM2 PF07145.15 EOO01648.1 - 0.39 10.5 5.4 0.05 13.3 0.4 2.3 2 0 0 2 2 2 0 Ataxin-2 C-terminal region SecE PF00584.20 EOO01649.1 - 2.4e-16 59.4 0.0 2.8e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Semialdhyde_dhC PF02774.18 EOO01650.1 - 5.1e-37 127.7 0.0 7.1e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EOO01650.1 - 4.6e-25 88.4 0.0 2.9e-24 85.8 0.0 2.3 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EOO01650.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CPSase_L_D2 PF02786.17 EOO01651.1 - 4.2e-74 248.6 0.0 7e-74 247.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 EOO01651.1 - 1e-36 125.3 0.0 2.1e-36 124.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 EOO01651.1 - 2.8e-36 124.4 0.0 5.7e-36 123.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 EOO01651.1 - 5e-17 61.5 0.9 1.8e-16 59.7 0.9 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 EOO01651.1 - 1.4e-08 34.6 0.0 2.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EOO01651.1 - 8.3e-08 32.0 0.0 1.9e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EOO01651.1 - 3e-06 26.9 0.0 0.036 13.9 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 EOO01651.1 - 3.4e-05 24.0 0.0 6.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EOO01651.1 - 0.00027 21.6 0.0 1.7 9.4 0.0 3.0 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_5 PF13549.6 EOO01651.1 - 0.002 17.6 0.2 0.0042 16.6 0.2 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EOO01651.1 - 0.012 14.9 0.0 0.032 13.5 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 EOO01651.1 - 0.015 14.9 0.0 0.066 12.8 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain HlyD_D23 PF16576.5 EOO01651.1 - 0.024 13.9 0.3 6 6.0 0.0 2.9 3 1 1 4 4 4 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF3182 PF11379.8 EOO01651.1 - 0.073 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) RimK PF08443.11 EOO01651.1 - 0.13 11.8 0.0 1.1 8.8 0.0 2.2 1 1 0 1 1 1 0 RimK-like ATP-grasp domain Fumble PF03630.14 EOO01652.1 - 3.5e-145 483.3 0.0 4.4e-145 483.0 0.0 1.1 1 0 0 1 1 1 1 Fumble Thioredoxin PF00085.20 EOO01653.1 - 2.5e-24 85.2 0.5 3.4e-24 84.8 0.1 1.4 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 EOO01653.1 - 1.6e-05 24.5 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EOO01653.1 - 1.9e-05 24.9 0.1 0.0024 18.2 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EOO01653.1 - 0.0001 22.7 0.2 0.00031 21.1 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 EOO01653.1 - 0.0073 16.0 0.5 0.59 9.8 0.0 2.3 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.21 EOO01653.1 - 0.024 14.6 0.2 4.4 7.2 0.1 2.2 1 1 1 2 2 2 0 AhpC/TSA family Thioredoxin_9 PF14595.6 EOO01653.1 - 0.04 13.7 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Phosducin PF02114.16 EOO01653.1 - 0.065 12.2 0.0 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 Phosducin SelK_SelG PF10961.8 EOO01653.1 - 0.087 13.4 0.4 0.087 13.4 0.4 2.2 1 1 1 2 2 2 0 Selenoprotein SelK_SelG RGS PF00615.19 EOO01654.1 - 2.4e-05 24.6 0.1 0.0019 18.5 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain Peptidase_C1_2 PF03051.15 EOO01655.1 - 1.6e-158 528.1 0.0 1.9e-158 527.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EOO01655.1 - 1e-07 32.3 0.2 0.0012 19.0 0.1 2.6 2 1 0 2 2 2 2 Papain family cysteine protease Herpes_BBRF1 PF04793.12 EOO01655.1 - 0.13 11.3 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 BRRF1-like protein Methyltransf_23 PF13489.6 EOO01656.1 - 1.6e-24 86.6 0.0 2.1e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO01656.1 - 1.3e-13 51.5 0.0 2.8e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO01656.1 - 9.4e-13 48.6 0.0 1.6e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO01656.1 - 6e-09 35.9 0.0 0.00054 19.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EOO01656.1 - 1.2e-08 35.6 0.0 1e-07 32.6 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EOO01656.1 - 0.00013 21.5 0.0 0.00035 20.1 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 EOO01656.1 - 0.00097 19.3 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 EOO01656.1 - 0.0015 17.8 0.0 0.0027 17.1 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EOO01656.1 - 0.0022 17.6 0.0 0.0072 15.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 EOO01656.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EOO01656.1 - 0.03 13.7 0.0 0.41 9.9 0.0 2.5 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EOO01656.1 - 0.035 13.4 0.1 0.085 12.1 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_16 PF10294.9 EOO01656.1 - 0.052 13.3 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase RNase_PH PF01138.21 EOO01657.1 - 1.1e-08 35.6 0.0 1.9e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EOO01657.1 - 6e-05 23.0 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 SnAC PF14619.6 EOO01657.1 - 0.068 13.8 0.2 0.13 12.8 0.2 1.5 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex Sugar_tr PF00083.24 EOO01658.1 - 4.8e-57 193.8 29.2 2.5e-38 132.1 11.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO01658.1 - 9.3e-20 70.8 33.3 1.2e-15 57.4 12.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily RhoGAP PF00620.27 EOO01662.1 - 5.1e-48 162.7 0.0 9.7e-48 161.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EOO01662.1 - 5.1e-13 49.1 0.2 2.1e-12 47.2 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain OmpH PF03938.14 EOO01662.1 - 0.00019 21.8 5.3 0.00019 21.8 5.3 2.8 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) Bac_small_YrzI PF09501.10 EOO01662.1 - 0.15 12.2 0.1 0.51 10.5 0.1 1.9 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) TPR_MLP1_2 PF07926.12 EOO01663.1 - 0.051 13.6 15.9 0.73 9.9 5.4 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 EOO01663.1 - 0.12 11.7 14.5 0.028 13.8 1.9 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2203 PF09969.9 EOO01663.1 - 0.5 11.1 10.2 1.8 9.3 3.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Uds1 PF15456.6 EOO01663.1 - 0.6 10.3 15.3 0.17 12.1 3.5 2.5 2 0 0 2 2 2 0 Up-regulated During Septation GREB1 PF15782.5 EOO01663.1 - 1.4 6.0 5.5 1.7 5.7 5.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4055 PF13264.6 EOO01663.1 - 1.7 8.8 5.9 0.4 10.8 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) DUF4140 PF13600.6 EOO01663.1 - 2.1 8.8 8.0 0.91 10.0 0.8 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.8 EOO01663.1 - 2.7 8.3 15.6 1 9.6 4.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SKA1 PF07160.12 EOO01663.1 - 4.9 6.9 18.6 1.4 8.7 4.3 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 MetOD2 PF18548.1 EOO01663.1 - 5.4 7.2 10.5 0.6 10.3 0.9 2.8 2 2 1 3 3 3 0 Metanogen output domain 2 Peptidase_C65 PF10275.9 EOO01664.1 - 3.4e-48 164.2 0.0 4.1e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain Asparaginase PF00710.20 EOO01665.1 - 3.1e-52 176.9 0.1 3.8e-52 176.6 0.1 1.1 1 0 0 1 1 1 1 Asparaginase, N-terminal Ras PF00071.22 EOO01666.1 - 6.4e-54 181.9 0.0 7.3e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EOO01666.1 - 2e-21 76.4 0.0 2.7e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EOO01666.1 - 1.3e-06 28.0 0.0 1.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PI-PLC-Y PF00387.19 EOO01667.1 - 4.3e-42 143.1 0.4 7.2e-42 142.4 0.4 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PI-PLC-X PF00388.19 EOO01667.1 - 2e-23 82.6 0.1 4.6e-23 81.4 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain BPL_LplA_LipB PF03099.19 EOO01669.1 - 4.6e-07 29.8 0.0 7.8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ApbA_C PF08546.11 EOO01670.1 - 2.4e-20 73.0 0.0 3.3e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pox_H7 PF04787.12 EOO01670.1 - 0.047 14.2 0.0 0.071 13.6 0.0 1.3 1 0 0 1 1 1 0 Late protein H7 TPR_10 PF13374.6 EOO01671.1 - 5e-12 45.3 5.6 0.026 14.4 0.1 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EOO01671.1 - 3.6e-10 40.0 1.0 0.012 15.9 0.4 6.2 5 1 0 5 5 5 2 Tetratricopeptide repeat UPF0242 PF06785.11 EOO01671.1 - 0.00045 20.4 4.8 0.0016 18.6 4.8 2.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus TPR_19 PF14559.6 EOO01671.1 - 0.01 16.3 2.6 12 6.5 0.1 4.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EOO01671.1 - 0.045 13.9 6.0 1.7 9.0 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Cep57_MT_bd PF06657.13 EOO01671.1 - 0.5 10.9 6.3 3 8.4 2.2 3.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TPR_20 PF14561.6 EOO01671.1 - 1.2 9.5 6.6 0.18 12.2 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Lar_restr_allev PF14354.6 EOO01671.1 - 1.7 9.0 3.8 2.6 8.5 0.1 3.2 3 0 0 3 3 3 0 Restriction alleviation protein Lar cwf21 PF08312.12 EOO01671.1 - 2 8.6 6.2 1.3 9.3 0.3 3.6 3 1 0 3 3 3 0 cwf21 domain TPR_14 PF13428.6 EOO01671.1 - 2.9 8.9 10.8 4.9 8.2 0.3 5.7 5 3 2 7 7 6 0 Tetratricopeptide repeat TMF_DNA_bd PF12329.8 EOO01671.1 - 4.9 7.2 9.6 43 4.2 9.6 2.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding NUDIX PF00293.28 EOO01672.1 - 4.4e-08 33.2 0.0 7.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Romo1 PF10247.9 EOO01673.1 - 7.2e-19 67.9 10.8 8.8e-17 61.2 10.8 2.2 1 1 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Sas10_Utp3 PF04000.15 EOO01674.1 - 1.8e-16 60.5 0.4 1.8e-16 60.5 0.4 2.2 2 0 0 2 2 2 1 Sas10/Utp3/C1D family OmpA PF00691.20 EOO01674.1 - 0.099 13.0 3.7 0.16 12.4 3.7 1.5 1 1 0 1 1 1 0 OmpA family NPV_P10 PF05531.12 EOO01674.1 - 0.35 11.3 3.7 6 7.4 0.2 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Hid1 PF12722.7 EOO01674.1 - 0.64 8.1 7.4 0.72 7.9 7.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CWC25 PF12542.8 EOO01675.1 - 4.3e-23 82.2 0.0 4.3e-23 82.2 0.0 3.1 2 1 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 EOO01675.1 - 1.8e-11 44.0 3.6 1.8e-11 44.0 3.6 3.4 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR TP_methylase PF00590.20 EOO01677.1 - 1.2e-44 152.8 0.3 6.1e-44 150.5 0.0 2.4 2 2 1 3 3 3 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EOO01677.1 - 4.6e-13 49.5 0.0 8.8e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 EOO01677.1 - 2.6e-10 39.6 0.1 5.9e-10 38.4 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 EOO01677.1 - 1.5e-09 37.3 0.0 9.1e-08 31.6 0.0 2.4 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal p450 PF00067.22 EOO01678.1 - 1.1e-46 159.5 0.4 7.1e-46 156.9 0.4 1.8 1 1 0 1 1 1 1 Cytochrome P450 NUDIX PF00293.28 EOO01679.1 - 3.8e-15 56.1 0.0 5.1e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DUF3880 PF12996.7 EOO01679.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) 4HBT PF03061.22 EOO01680.1 - 1.5e-06 28.5 0.1 2.8e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily YtxH PF12732.7 EOO01680.1 - 3 8.5 4.9 9.8 6.8 0.2 2.5 2 0 0 2 2 2 0 YtxH-like protein Ras PF00071.22 EOO01682.1 - 3.2e-54 182.9 0.0 3.8e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EOO01682.1 - 1.2e-21 77.1 0.0 2.4e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EOO01682.1 - 6.2e-09 35.5 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EOO01682.1 - 0.0014 18.0 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EOO01682.1 - 0.0039 16.4 0.0 0.0064 15.7 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 EOO01682.1 - 0.0057 16.1 0.0 0.0077 15.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EOO01682.1 - 0.0085 16.2 0.0 0.018 15.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EOO01682.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.4 1 1 0 1 1 1 0 ABC transporter FAD_binding_7 PF03441.14 EOO01683.1 - 8.2e-44 149.5 0.5 1.4e-43 148.7 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EOO01683.1 - 2.3e-17 63.5 0.0 4.4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase adh_short_C2 PF13561.6 EOO01684.1 - 2.4e-29 102.6 4.6 2.9e-29 102.3 4.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO01684.1 - 2.8e-19 69.3 3.2 3.8e-19 68.9 3.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO01684.1 - 0.00042 20.3 0.8 0.0008 19.4 0.8 1.4 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EOO01684.1 - 0.0077 15.6 0.1 0.021 14.2 0.1 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 EOO01684.1 - 0.08 13.4 0.1 0.17 12.4 0.1 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.21 EOO01684.1 - 0.16 11.3 0.1 0.32 10.3 0.0 1.4 1 1 0 1 1 1 0 ThiF family PI-PLC-X PF00388.19 EOO01685.1 - 1.4e-12 47.4 0.1 2e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SIR2 PF02146.17 EOO01686.1 - 2.2e-45 154.8 0.0 3.6e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family adh_short PF00106.25 EOO01687.1 - 1.1e-33 116.4 0.0 1.5e-19 70.2 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EOO01687.1 - 3.9e-26 92.0 0.1 5.1e-14 52.4 0.1 2.8 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO01687.1 - 1.5e-08 34.8 0.0 4.3e-05 23.5 0.1 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 EOO01687.1 - 0.075 12.5 0.8 0.19 11.1 0.2 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1687 PF07955.11 EOO01688.1 - 2.2e-36 125.1 0.5 2.9e-36 124.7 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) CMS1 PF14617.6 EOO01689.1 - 1.6e-82 276.6 2.1 1.9e-82 276.4 2.1 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 EOO01689.1 - 0.00034 20.4 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2384 PF09722.10 EOO01689.1 - 0.066 13.3 0.0 0.41 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) NFACT-C PF11923.8 EOO01690.1 - 1.8e-37 127.4 0.1 1.8e-37 127.4 0.1 3.7 3 0 0 3 3 3 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 EOO01690.1 - 2.1e-33 115.2 0.0 5.8e-33 113.8 0.0 1.8 1 0 0 1 1 1 1 NFACT protein RNA binding domain FbpA PF05833.11 EOO01690.1 - 6e-31 107.7 11.6 6e-31 107.7 11.6 2.8 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Myb_DNA-binding PF00249.31 EOO01691.1 - 3.6e-16 59.1 0.2 2.3e-08 34.1 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EOO01691.1 - 8.2e-12 45.2 0.5 2.2e-05 24.6 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EOO01691.1 - 2.3e-07 30.8 0.2 0.012 15.6 0.0 2.7 2 0 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EOO01691.1 - 0.017 15.3 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 SURF1 PF02104.15 EOO01692.1 - 8.7e-47 159.6 0.1 1.3e-46 159.1 0.1 1.2 1 0 0 1 1 1 1 SURF1 family Rsm22 PF09243.10 EOO01693.1 - 1.3e-30 106.6 0.0 5e-30 104.7 0.0 1.9 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Lactonase PF10282.9 EOO01693.1 - 5.4e-10 39.1 1.6 0.00028 20.3 0.0 3.6 3 1 1 4 4 4 2 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 EOO01693.1 - 1.2e-07 30.6 0.1 0.00023 19.8 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain Methyltransf_23 PF13489.6 EOO01693.1 - 3.7e-05 23.6 0.0 9.3e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_S4e PF00900.20 EOO01695.1 - 3.3e-36 123.0 0.1 7e-36 122.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EOO01695.1 - 5.1e-24 83.6 0.1 8.3e-24 83.0 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EOO01695.1 - 3.5e-18 65.4 5.3 6.8e-18 64.5 5.3 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EOO01695.1 - 2.1e-06 27.3 0.0 4.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 EOO01695.1 - 3.9e-06 26.6 1.7 3.9e-06 26.6 1.7 3.1 4 0 0 4 4 4 1 KOW motif RdRP PF05183.12 EOO01697.1 - 9e-187 622.3 0.0 1.2e-186 621.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF1348 PF07080.11 EOO01698.1 - 1.3e-63 212.7 9.1 1.6e-63 212.4 9.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 EOO01698.1 - 1.4e-06 28.9 1.0 2e-06 28.4 1.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EOO01698.1 - 0.00035 20.9 0.1 0.00053 20.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) dsDNA_bind PF01984.20 EOO01700.1 - 5.5e-43 145.8 13.6 6.4e-43 145.6 13.6 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain CDT1_C PF16679.5 EOO01700.1 - 0.055 13.9 1.4 0.077 13.4 1.4 1.2 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Tom5 PF10642.9 EOO01700.1 - 0.081 13.0 1.3 0.18 11.9 0.7 1.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Alb1 PF09135.11 EOO01700.1 - 0.088 13.7 5.8 2.2 9.2 0.4 2.2 2 0 0 2 2 2 0 Alb1 Gal4_dimer PF03902.13 EOO01700.1 - 0.42 10.8 3.5 20 5.4 0.0 3.6 3 1 0 3 3 3 0 Gal4-like dimerisation domain WD40 PF00400.32 EOO01701.1 - 1.6e-18 66.7 21.1 8e-05 23.3 1.0 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO01701.1 - 0.00011 22.4 0.0 0.055 13.8 0.0 3.5 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain CDC45 PF02724.14 EOO01701.1 - 2.9 6.1 6.5 4.4 5.5 6.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Sel1 PF08238.12 EOO01702.1 - 5.3e-49 163.5 25.6 1.5e-08 35.0 0.0 8.0 8 0 0 8 8 8 7 Sel1 repeat DUF1176 PF06674.11 EOO01702.1 - 0.13 11.7 0.5 0.2 11.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Clathrin-link PF09268.10 EOO01702.1 - 0.14 11.6 0.2 0.34 10.3 0.2 1.7 1 0 0 1 1 1 0 Clathrin, heavy-chain linker Putative_PNPOx PF01243.20 EOO01703.1 - 0.00016 21.8 0.0 0.00056 20.0 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Gln-synt_C PF00120.24 EOO01705.1 - 4.7e-85 285.6 0.0 5.8e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 EOO01705.1 - 0.057 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain Alpha-amylase PF00128.24 EOO01706.1 - 3e-18 66.5 0.0 3.2e-15 56.5 0.0 2.5 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 EOO01706.1 - 8.3e-16 58.4 0.0 1.4e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EOO01706.1 - 3.8e-06 26.6 0.0 6.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EOO01706.1 - 0.01 15.9 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_hydro_16 PF00722.21 EOO01707.1 - 3.7e-41 140.5 0.7 6.1e-41 139.8 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PgaD PF13994.6 EOO01707.1 - 0.058 13.5 0.0 0.092 12.8 0.0 1.2 1 0 0 1 1 1 0 PgaD-like protein GFO_IDH_MocA_C PF02894.17 EOO01708.1 - 1.2e-17 63.9 0.4 6e-17 61.7 0.3 2.2 2 1 1 3 3 3 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 EOO01708.1 - 3.8e-17 63.2 0.0 6.9e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Amidase PF01425.21 EOO01709.1 - 7.4e-71 239.4 0.6 5.2e-66 223.5 0.1 2.1 2 0 0 2 2 2 2 Amidase DUF1593 PF07632.11 EOO01710.1 - 6.1e-61 206.1 0.0 9.3e-61 205.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) Methyltransf_23 PF13489.6 EOO01711.1 - 2e-17 63.5 0.0 3e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO01711.1 - 7.9e-12 45.7 0.0 1.5e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO01711.1 - 1.3e-08 35.4 0.0 2.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO01711.1 - 3.8e-08 33.3 0.0 3.1e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO01711.1 - 2.6e-06 28.1 0.0 1.5e-05 25.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EOO01711.1 - 0.01 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 EOO01711.1 - 0.019 14.4 0.0 0.04 13.3 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 EOO01711.1 - 0.028 13.9 0.0 0.062 12.8 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 EOO01711.1 - 0.032 13.8 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 EOO01711.1 - 0.064 12.5 0.1 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain CheR PF01739.18 EOO01711.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 EOO01711.1 - 0.15 11.4 0.0 0.57 9.5 0.0 2.0 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Sugar_tr PF00083.24 EOO01712.1 - 1.3e-73 248.4 16.9 4.3e-57 194.0 5.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter Aldolase_II PF00596.21 EOO01713.1 - 7.3e-40 136.9 0.1 8.6e-40 136.7 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SFTA2 PF15210.6 EOO01714.1 - 0.21 11.6 1.7 18 5.4 0.0 3.5 2 1 1 3 3 3 0 Surfactant-associated protein 2 Nop14 PF04147.12 EOO01715.1 - 0.06 11.6 9.7 0.079 11.2 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.11 EOO01715.1 - 0.13 12.2 19.7 0.25 11.3 19.7 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) YL1 PF05764.13 EOO01715.1 - 0.33 11.0 16.1 0.064 13.4 12.4 1.6 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 EOO01715.1 - 0.5 8.6 10.2 0.73 8.0 10.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_A_type_inc PF04508.12 EOO01716.1 - 0.16 11.8 9.9 15 5.6 0.0 4.9 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF99 PF01949.16 EOO01716.1 - 6.7 6.1 10.7 6.5 6.1 1.4 3.3 1 1 2 3 3 3 0 Protein of unknown function DUF99 RNA_pol_Rpb1_1 PF04997.12 EOO01717.1 - 6.6e-82 275.3 0.1 1.1e-81 274.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EOO01717.1 - 2.3e-77 260.1 0.3 4.4e-77 259.1 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EOO01717.1 - 5e-74 248.0 0.5 1.7e-73 246.3 0.0 2.2 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_4 PF05000.17 EOO01717.1 - 4.4e-29 100.6 0.1 1.4e-28 99.0 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.18 EOO01717.1 - 2.2e-17 63.4 0.0 5.7e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 Mito_carr PF00153.27 EOO01718.1 - 4e-73 241.4 1.7 2.8e-23 81.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EOO01718.1 - 3.1e-05 23.3 0.3 0.0024 17.1 0.1 3.3 3 1 0 3 3 3 1 Gammaproteobacterial serine protease GAD-like PF08887.11 EOO01718.1 - 0.043 13.6 0.0 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 GAD-like domain Glyco_hydro_61 PF03443.14 EOO01719.1 - 2.9e-30 105.8 0.2 6.5e-30 104.6 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_6 PF01341.17 EOO01720.1 - 2.5e-76 257.4 3.0 2.2e-60 205.0 2.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 6 FtsJ PF01728.19 EOO01721.1 - 2.6e-41 141.6 0.0 3.3e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase RRM_1 PF00076.22 EOO01722.1 - 6.7e-05 22.6 0.0 0.00019 21.2 0.1 1.7 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.7 EOO01723.1 - 0.00082 19.9 0.0 0.0015 19.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-RING_UBOX PF13445.6 EOO01723.1 - 0.04 13.9 0.4 0.092 12.8 0.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 EOO01723.1 - 4.7 7.6 12.4 0.9 9.9 8.5 1.9 2 1 0 2 2 2 0 Ring finger domain Glyco_hydro_39 PF01229.17 EOO01724.1 - 0.001 17.8 0.1 0.0014 17.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 GMC_oxred_C PF05199.13 EOO01725.1 - 7.8e-24 84.8 0.3 1.4e-23 84.0 0.3 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EOO01725.1 - 4.7e-23 82.0 0.0 7.4e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.18 EOO01725.1 - 1.6e-07 31.1 2.0 1.6e-07 31.1 2.0 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain FAD_binding_2 PF00890.24 EOO01725.1 - 0.0008 18.6 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_61 PF03443.14 EOO01726.1 - 2.8e-42 145.0 0.1 3.7e-42 144.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Peptidase_C53 PF05550.11 EOO01726.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 CH PF00307.31 EOO01727.1 - 8.5e-72 238.3 0.0 4.2e-19 68.7 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 EOO01727.1 - 2e-07 31.4 0.3 2.7e-06 27.7 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EOO01727.1 - 2.1e-05 23.7 1.4 0.58 9.8 0.3 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EOO01727.1 - 0.024 14.5 3.7 0.18 11.8 0.1 3.3 4 0 0 4 4 4 0 EF-hand domain MBOAT PF03062.19 EOO01728.1 - 9.6e-37 127.1 17.3 9.6e-37 127.1 17.3 2.2 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EOO01728.1 - 1.6e-05 25.1 4.1 3.9e-05 23.8 4.1 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Ribosomal_L18 PF17135.4 EOO01729.1 - 1.8e-92 307.9 3.7 2e-92 307.7 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EOO01729.1 - 0.014 16.0 0.1 0.014 16.0 0.1 2.2 2 1 0 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Sugar_tr PF00083.24 EOO01730.1 - 9.9e-34 117.0 0.7 1.4e-33 116.5 0.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Nebulin PF00880.18 EOO01730.1 - 0.19 11.7 0.2 1.4 8.9 0.3 2.0 2 0 0 2 2 2 0 Nebulin repeat OST3_OST6 PF04756.13 EOO01731.1 - 3.9e-107 358.0 0.0 4.9e-107 357.6 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HisKA_7TM PF16927.5 EOO01731.1 - 0.015 15.3 4.1 0.022 14.8 4.1 1.2 1 0 0 1 1 1 0 N-terminal 7TM region of histidine kinase MerC PF03203.14 EOO01731.1 - 0.21 12.1 4.3 3.6 8.1 0.2 2.5 2 0 0 2 2 2 0 MerC mercury resistance protein Sedlin_N PF04628.13 EOO01732.1 - 9.2e-12 45.2 0.0 1.7e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Acyl_transf_1 PF00698.21 EOO01732.1 - 5.4e-11 42.6 0.0 7.2e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Acyl transferase domain Sybindin PF04099.12 EOO01732.1 - 0.06 13.3 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Sybindin-like family IU_nuc_hydro PF01156.19 EOO01735.1 - 1.2e-14 54.6 0.0 1.4e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Xan_ur_permease PF00860.20 EOO01737.1 - 3.5e-40 137.9 20.8 1.5e-39 135.8 20.8 1.8 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 EOO01737.1 - 0.017 15.5 5.3 0.017 15.5 5.3 3.2 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily PH_10 PF15411.6 EOO01738.1 - 7.2e-42 142.5 0.2 1.4e-41 141.6 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 EOO01738.1 - 1.6e-31 108.4 0.0 3.5e-31 107.3 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 EOO01738.1 - 6.2e-19 68.9 0.0 1.2e-18 68.0 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 EOO01738.1 - 1.5e-08 34.4 0.0 3.4e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 PB1 domain CH PF00307.31 EOO01738.1 - 0.012 15.8 0.0 0.033 14.4 0.0 1.8 1 0 0 1 1 1 0 Calponin homology (CH) domain DUF4071 PF13281.6 EOO01738.1 - 0.057 12.5 0.1 0.12 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) NUDE_C PF04880.13 EOO01739.1 - 1.9e-42 145.8 8.4 1.9e-42 145.8 8.4 3.3 2 2 3 5 5 5 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 EOO01739.1 - 0.00056 20.3 7.7 0.00056 20.3 7.7 3.7 1 1 3 4 4 4 1 Cell division protein ZapB CENP-F_leu_zip PF10473.9 EOO01739.1 - 0.034 14.2 30.4 0.32 11.0 10.2 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 EOO01739.1 - 0.036 13.6 29.6 0.11 12.0 29.6 1.6 1 1 0 1 1 1 0 Intermediate filament protein EF1G PF00647.19 EOO01739.1 - 0.14 12.2 1.6 0.4 10.8 0.2 2.2 1 1 1 2 2 2 0 Elongation factor 1 gamma, conserved domain Fez1 PF06818.15 EOO01739.1 - 0.18 12.3 24.4 0.33 11.4 12.0 2.2 1 1 1 2 2 2 0 Fez1 DUF745 PF05335.13 EOO01739.1 - 0.44 10.3 14.3 0.026 14.3 8.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF745) ERM PF00769.19 EOO01739.1 - 1.1 9.0 31.2 0.049 13.4 16.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ATG16 PF08614.11 EOO01739.1 - 1.5 9.0 29.1 1 9.6 14.6 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 EOO01739.1 - 1.8 8.6 15.6 0.39 10.7 1.7 3.5 1 1 1 3 3 3 0 Laminin Domain II FPP PF05911.11 EOO01739.1 - 1.9 6.6 25.7 16 3.5 25.4 1.8 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Tropomyosin_1 PF12718.7 EOO01739.1 - 3 8.0 33.4 14 5.9 6.5 3.2 1 1 1 2 2 2 0 Tropomyosin like Chibby PF14645.6 EOO01739.1 - 3.5 8.1 9.6 5.4 7.5 3.0 2.3 1 1 1 2 2 2 0 Chibby family PRKG1_interact PF15898.5 EOO01739.1 - 5.5 8.0 26.8 1.4 9.8 12.0 2.9 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain AAA_13 PF13166.6 EOO01739.1 - 6.5 5.3 20.2 8.2 4.9 20.2 1.1 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.12 EOO01739.1 - 8.4 6.5 32.8 27 4.8 4.5 3.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein FliD_N PF02465.18 EOO01739.1 - 9.3 7.0 9.9 2.5 8.9 0.3 3.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus ACC_central PF08326.12 EOO01740.1 - 5.4e-281 934.1 0.0 7.5e-281 933.6 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EOO01740.1 - 9.2e-187 621.6 0.0 1.2e-186 621.2 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EOO01740.1 - 5.9e-52 176.2 0.0 1.2e-51 175.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EOO01740.1 - 8.1e-28 97.2 0.1 1.7e-27 96.1 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EOO01740.1 - 3.9e-21 75.2 0.0 8.3e-19 67.7 0.0 2.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EOO01740.1 - 2.7e-17 62.4 0.1 7e-17 61.0 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EOO01740.1 - 0.0025 17.6 0.0 0.013 15.4 0.0 2.2 1 0 0 1 1 1 1 Biotin-lipoyl like GxGYxYP_N PF16216.5 EOO01740.1 - 0.0042 17.3 0.1 0.0089 16.2 0.1 1.5 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal ATPgrasp_Ter PF15632.6 EOO01740.1 - 0.1 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EOO01740.1 - 0.1 12.6 0.0 0.32 11.0 0.0 1.9 1 0 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EOO01740.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF1722 PF08349.11 EOO01741.1 - 0.16 12.3 0.0 1.1 9.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) Sugar_tr PF00083.24 EOO01742.1 - 3.4e-63 214.1 29.2 4e-63 213.8 29.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO01742.1 - 1.7e-23 83.1 27.8 2.6e-23 82.5 27.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.6 EOO01743.1 - 8.3e-52 176.4 0.0 1.1e-51 176.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65N PF03636.15 EOO01743.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Carn_acyltransf PF00755.20 EOO01743.1 - 0.27 9.8 0.0 0.41 9.2 0.0 1.2 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase CBP_BcsF PF11120.8 EOO01744.1 - 0.0012 18.9 0.0 18 5.5 0.0 4.2 4 0 0 4 4 4 3 Cellulose biosynthesis protein BcsF Abhydrolase_1 PF00561.20 EOO01745.1 - 5e-24 85.3 0.0 6.3e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EOO01745.1 - 1.1e-12 49.1 0.0 1.4e-12 48.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EOO01745.1 - 1.6e-08 34.1 0.0 1.4e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EOO01745.1 - 8.4e-05 21.4 0.0 0.00085 18.1 0.0 2.0 1 1 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 EOO01745.1 - 0.00046 20.3 0.0 0.00094 19.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Ser_hydrolase PF06821.13 EOO01745.1 - 0.11 12.4 0.0 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase Amidase PF01425.21 EOO01746.1 - 1.7e-34 119.6 0.8 2.3e-34 119.2 0.8 1.2 1 0 0 1 1 1 1 Amidase MR_MLE_C PF13378.6 EOO01747.1 - 1.7e-48 165.1 0.1 2.7e-48 164.5 0.1 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EOO01747.1 - 1.6e-06 28.3 0.0 3.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 EOO01747.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus 3Beta_HSD PF01073.19 EOO01748.1 - 3.2e-06 26.4 0.1 3.9e-06 26.1 0.1 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EOO01748.1 - 0.00019 20.7 0.0 0.00069 18.9 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 EOO01748.1 - 0.00063 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EOO01748.1 - 0.00072 19.1 0.1 0.0016 17.9 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peptidase_S8 PF00082.22 EOO01749.1 - 2e-19 70.0 11.7 2.2e-19 69.9 11.7 1.0 1 0 0 1 1 1 1 Subtilase family DUF21 PF01595.20 EOO01749.1 - 0.0061 16.3 0.2 0.0086 15.8 0.2 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain MAT1-1-2 PF17043.5 EOO01750.1 - 0.07 13.0 0.1 0.26 11.1 0.0 1.7 1 1 1 2 2 2 0 Mating type protein 1-1-2 of unknown function Sacchrp_dh_NADP PF03435.18 EOO01751.1 - 1.5e-07 31.7 0.0 2.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Het-C PF07217.11 EOO01752.1 - 8.5e-125 417.4 0.1 3e-98 329.8 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein Het-C Apolipoprotein PF01442.18 EOO01752.1 - 4.7e-06 26.6 0.3 0.00025 21.0 0.5 2.0 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Chlorosome_CsmC PF11098.8 EOO01752.1 - 0.0028 17.6 11.1 0.0079 16.2 2.6 3.1 2 1 1 3 3 3 2 Chlorosome envelope protein C ApoLp-III PF07464.11 EOO01752.1 - 0.0077 16.3 0.8 0.23 11.6 0.1 3.3 2 1 1 3 3 3 1 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 EOO01752.1 - 0.015 15.9 8.6 0.016 15.8 1.5 3.8 3 1 2 5 5 4 0 Bacterial protein of unknown function (DUF883) Tape_meas_lam_C PF09718.10 EOO01752.1 - 0.046 13.9 0.2 24 5.2 0.0 4.0 1 1 2 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Phasin PF05597.11 EOO01752.1 - 0.046 13.7 8.0 0.24 11.4 1.4 3.7 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Caskin-tail PF16632.5 EOO01752.1 - 0.14 12.6 0.2 5.6 7.5 0.0 3.4 2 1 1 3 3 3 0 C-terminal region of Caskin Phasin_2 PF09361.10 EOO01752.1 - 0.16 12.2 0.3 0.6 10.4 0.1 2.1 2 0 0 2 2 2 0 Phasin protein YtxH PF12732.7 EOO01752.1 - 0.19 12.3 10.4 98 3.6 6.9 4.2 2 1 0 2 2 2 0 YtxH-like protein MCPsignal PF00015.21 EOO01752.1 - 0.8 9.5 6.7 0.83 9.4 2.2 3.0 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain V-ATPase_G_2 PF16999.5 EOO01752.1 - 1.4 9.4 4.4 0.33 11.4 0.6 1.9 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Collagen_mid PF15984.5 EOO01752.1 - 1.6 8.5 4.6 5.2 6.8 0.4 3.6 2 1 1 3 3 3 0 Bacterial collagen, middle region EspB PF05802.11 EOO01752.1 - 6.2 6.8 11.7 20 5.1 1.9 2.9 1 1 1 2 2 2 0 Enterobacterial EspB protein Methyltransf_2 PF00891.18 EOO01753.1 - 9.2e-22 77.4 0.0 2.2e-21 76.1 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain Sugar_tr PF00083.24 EOO01754.1 - 1.9e-103 346.8 20.5 2.3e-103 346.5 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO01754.1 - 1e-22 80.6 15.2 1e-22 80.6 15.2 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily ATP-synt_ab PF00006.25 EOO01755.1 - 2.4e-74 249.6 0.0 4.1e-74 248.8 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EOO01755.1 - 1.1e-47 161.5 0.5 1.8e-47 160.8 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EOO01755.1 - 4.2e-15 56.0 3.0 1.1e-14 54.7 3.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain MFS_1 PF07690.16 EOO01756.1 - 1.8e-32 112.6 23.2 9.4e-32 110.3 22.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EOO01756.1 - 0.007 15.7 5.9 0.007 15.7 5.9 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Aldedh PF00171.22 EOO01757.1 - 6.3e-124 414.0 0.0 8.1e-124 413.6 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short PF00106.25 EOO01757.1 - 1e-36 126.3 1.9 2e-36 125.3 1.9 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO01757.1 - 8.6e-36 123.7 1.1 1.8e-35 122.6 1.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO01757.1 - 6.9e-08 32.6 0.6 1.2e-07 31.8 0.6 1.3 1 0 0 1 1 1 1 KR domain LuxC PF05893.14 EOO01757.1 - 0.00014 21.0 0.1 0.007 15.5 0.0 2.6 2 1 0 2 2 2 1 Acyl-CoA reductase (LuxC) 3HCDH_N PF02737.18 EOO01757.1 - 0.00089 19.2 0.6 0.0055 16.6 0.3 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ChuX_HutX PF06228.13 EOO01757.1 - 0.02 14.6 0.0 3.9 7.3 0.0 2.7 1 1 0 2 2 2 0 Haem utilisation ChuX/HutX Acetyltransf_18 PF18014.1 EOO01757.1 - 0.091 12.6 0.0 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SnoaL_4 PF13577.6 EOO01759.1 - 0.009 16.1 0.3 0.017 15.2 0.3 1.5 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 EOO01759.1 - 0.11 12.8 0.1 0.12 12.7 0.1 1.1 1 0 0 1 1 1 0 SnoaL-like domain Carb_kinase PF01256.17 EOO01760.1 - 2.1e-57 194.4 0.1 2.9e-57 194.0 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 EOO01760.1 - 0.00036 20.0 0.0 0.00067 19.1 0.0 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 EOO01760.1 - 0.046 13.1 0.1 0.17 11.2 0.1 1.9 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase APG12 PF04110.13 EOO01762.1 - 1.1e-25 89.8 0.0 1.5e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EOO01762.1 - 0.00049 20.2 0.0 0.00061 19.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Cellulase PF00150.18 EOO01763.1 - 2.9e-12 46.6 0.5 2.9e-12 46.6 0.5 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) BCCT PF02028.17 EOO01763.1 - 0.35 9.2 2.8 0.47 8.8 2.8 1.2 1 0 0 1 1 1 0 BCCT, betaine/carnitine/choline family transporter Dfp1_Him1_M PF08630.10 EOO01764.1 - 3.3e-45 153.4 0.0 8.1e-45 152.1 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 EOO01764.1 - 3.3e-21 75.1 0.1 6.5e-21 74.2 0.1 1.5 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 EOO01764.1 - 0.0056 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain PNP_UDP_1 PF01048.20 EOO01765.1 - 3.6e-37 127.9 0.8 4.6e-37 127.5 0.8 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily F-actin_cap_A PF01267.17 EOO01766.1 - 1.3e-97 326.4 0.0 1.5e-97 326.2 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Med13_C PF06333.12 EOO01768.1 - 3.7e-60 203.9 0.5 4.1e-60 203.8 0.5 1.0 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain WD40 PF00400.32 EOO01769.1 - 6.5e-13 48.9 2.8 3.3e-05 24.6 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO01769.1 - 2.6e-08 34.1 0.0 0.00012 22.4 0.0 3.4 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EOO01769.1 - 0.0091 15.9 0.0 3.1 7.8 0.0 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EOO01769.1 - 0.021 13.3 0.0 0.063 11.8 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain eIF2A PF08662.11 EOO01769.1 - 0.025 14.4 0.1 0.18 11.7 0.0 2.3 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 EOO01769.1 - 0.045 12.8 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain ParA PF10609.9 EOO01770.1 - 5e-62 209.5 0.0 5.6e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_26 PF13500.6 EOO01770.1 - 0.016 15.1 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain Kinocilin PF15033.6 EOO01770.1 - 0.02 14.5 0.0 0.052 13.2 0.0 1.7 2 0 0 2 2 2 0 Kinocilin protein Glyco_hydro_7 PF00840.20 EOO01771.1 - 8.7e-207 687.1 19.8 9.8e-207 686.9 19.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 OCD_Mu_crystall PF02423.15 EOO01772.1 - 3.6e-15 55.7 0.2 1.1e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EOO01772.1 - 0.015 15.3 0.0 1 9.4 0.0 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Herpes_pp85 PF04637.12 EOO01772.1 - 7.4 4.9 6.0 11 4.3 6.0 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Aminotran_1_2 PF00155.21 EOO01773.1 - 1.3e-36 126.5 0.0 2e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EOO01773.1 - 0.032 13.0 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase DUF1593 PF07632.11 EOO01774.1 - 1.6e-69 234.3 0.0 2e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 EOO01774.1 - 0.0057 15.5 0.0 0.0079 15.0 0.0 1.2 1 0 0 1 1 1 1 REJ domain HSP9_HSP12 PF04119.12 EOO01774.1 - 0.077 13.4 0.1 4.1 7.9 0.0 3.1 3 0 0 3 3 3 0 Heat shock protein 9/12 SIR2 PF02146.17 EOO01775.1 - 1.5e-21 77.1 0.0 3.4e-21 76.0 0.0 1.6 1 1 0 1 1 1 1 Sir2 family DUF1936 PF09151.10 EOO01775.1 - 0.018 15.0 3.7 1.5 8.8 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) NAD_binding_10 PF13460.6 EOO01776.1 - 1.2e-09 38.3 0.8 1.8e-09 37.8 0.8 1.3 1 0 0 1 1 1 1 NAD(P)H-binding HIM1 PF08732.10 EOO01776.1 - 4.7e-09 36.0 0.0 6.6e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 HIM1 Epimerase PF01370.21 EOO01776.1 - 7.4e-09 35.4 0.0 1.3e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EOO01776.1 - 7.8e-05 22.3 0.7 0.00042 20.0 0.7 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EOO01776.1 - 0.0084 15.3 0.0 3.9 6.6 0.0 2.8 2 1 1 3 3 3 2 Male sterility protein Semialdhyde_dh PF01118.24 EOO01776.1 - 0.042 14.3 0.1 0.14 12.6 0.0 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EOO01776.1 - 0.068 12.2 0.1 1.2 8.1 0.1 2.5 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Atx10homo_assoc PF09759.9 EOO01777.1 - 3.1e-12 46.4 0.0 7.8e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Zip PF02535.22 EOO01777.1 - 0.23 10.6 14.5 0.41 9.8 14.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter NeA_P2 PF12312.8 EOO01777.1 - 0.79 9.1 3.4 1.5 8.2 3.4 1.4 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Arrestin_C PF02752.22 EOO01778.1 - 1.9e-15 57.5 0.0 8.9e-15 55.3 0.1 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EOO01778.1 - 1.7e-13 50.9 0.0 2.6e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 EOO01778.1 - 0.0027 17.4 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like RPN7 PF10602.9 EOO01779.1 - 7.1e-57 191.9 1.7 8.8e-57 191.6 0.4 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 EOO01779.1 - 3e-14 53.4 0.0 7.2e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain CobT PF06213.12 EOO01780.1 - 0.0066 15.9 0.0 0.0066 15.9 0.0 2.6 2 1 1 3 3 3 1 Cobalamin biosynthesis protein CobT DHBP_synthase PF00926.19 EOO01781.1 - 2.2e-84 281.8 0.0 2.5e-84 281.6 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Pro_CA PF00484.19 EOO01782.1 - 1.6e-46 158.4 0.1 1.9e-46 158.2 0.1 1.0 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_1 PF00561.20 EOO01782.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold TauD PF02668.16 EOO01783.1 - 1e-42 146.8 0.2 1.7e-42 146.1 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MOZ_SAS PF01853.18 EOO01784.1 - 1.7e-76 255.8 0.0 2.4e-76 255.4 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EOO01784.1 - 6e-21 73.8 3.4 1.5e-20 72.6 3.4 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 EOO01784.1 - 0.0015 18.5 2.4 0.006 16.6 2.4 2.1 1 0 0 1 1 1 1 PHD-finger Acetyltransf_7 PF13508.7 EOO01784.1 - 0.16 12.4 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Gram_pos_anchor PF00746.21 EOO01785.1 - 0.23 11.5 1.3 0.64 10.0 1.3 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif ApbA PF02558.16 EOO01786.1 - 8.6e-28 96.9 0.0 1.2e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EOO01786.1 - 6.6e-25 87.7 0.0 2.2e-24 86.0 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal NPV_P10 PF05531.12 EOO01787.1 - 0.031 14.7 0.2 0.031 14.7 0.2 6.6 5 3 2 7 7 7 0 Nucleopolyhedrovirus P10 protein DUF3786 PF12654.7 EOO01787.1 - 0.033 13.8 0.7 0.08 12.5 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Ykof PF07615.11 EOO01787.1 - 0.18 12.3 0.0 3.6 8.1 0.0 2.8 2 0 0 2 2 2 0 YKOF-related Family AvrLm4-7 PF18661.1 EOO01787.1 - 1.7 9.7 8.7 25 6.0 0.9 4.0 3 1 0 3 3 3 0 Avirulence Effector AvrLm4-7 PhoQ_Sensor PF08918.10 EOO01787.1 - 2.1 8.2 6.4 0.89 9.4 0.5 2.9 2 0 0 2 2 2 0 PhoQ Sensor MFS_1 PF07690.16 EOO01788.1 - 9.2e-47 159.7 33.9 3.2e-46 157.9 28.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EOO01788.1 - 5e-10 38.4 2.8 7.5e-10 37.9 2.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EOO01788.1 - 1.1e-06 27.8 24.8 2.8e-06 26.5 24.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2178 PF09946.9 EOO01788.1 - 0.53 10.5 8.9 10 6.4 1.1 3.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2178) PAS PF00989.25 EOO01789.1 - 0.0028 17.7 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold Sugar_tr PF00083.24 EOO01790.1 - 5.1e-70 236.6 21.8 6.1e-70 236.3 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO01790.1 - 2e-13 50.0 25.1 5.9e-13 48.5 23.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Thiolase_N PF00108.23 EOO01791.1 - 3.4e-73 246.2 3.5 4.5e-73 245.8 3.5 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EOO01791.1 - 6.1e-44 148.6 0.2 1.2e-43 147.7 0.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EOO01791.1 - 0.014 15.0 2.1 0.064 12.8 0.6 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Cadherin_tail PF15974.5 EOO01791.1 - 0.15 12.4 0.3 0.27 11.6 0.3 1.5 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region PEX11 PF05648.14 EOO01792.1 - 4.4e-73 245.4 0.4 4.9e-73 245.3 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ENTH PF01417.20 EOO01793.1 - 4.4e-49 165.7 0.1 7e-49 165.0 0.1 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 EOO01793.1 - 1.4e-07 31.8 45.8 1.4e-07 31.8 45.8 5.0 1 1 1 2 2 2 1 Domain of unknown function (DUF1720) UIM PF02809.20 EOO01793.1 - 0.0068 16.3 0.6 0.0068 16.3 0.6 3.2 3 0 0 3 3 3 1 Ubiquitin interaction motif ANTH PF07651.16 EOO01793.1 - 0.011 14.8 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 0 ANTH domain VHS PF00790.19 EOO01793.1 - 0.04 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 VHS domain AIDA PF16168.5 EOO01793.1 - 0.091 12.9 0.3 0.25 11.4 0.3 1.7 2 0 0 2 2 2 0 Adhesin of bacterial autotransporter system, probable stalk DUF4264 PF14084.6 EOO01793.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Yae1_N PF09811.9 EOO01793.1 - 2.6 7.8 5.9 4.7 7.0 0.5 3.1 3 0 0 3 3 3 0 Essential protein Yae1, N terminal EF_assoc_2 PF08356.12 EOO01794.1 - 8.8e-35 118.6 0.0 1.8e-34 117.5 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 EOO01794.1 - 7.2e-31 105.6 0.5 1.6e-30 104.5 0.5 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 EOO01794.1 - 7.9e-24 84.1 0.0 9.9e-16 57.7 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EOO01794.1 - 2.6e-14 53.5 0.0 4.7e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 EOO01794.1 - 1.6e-08 33.5 2.9 0.0046 16.4 0.4 2.8 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.23 EOO01794.1 - 5.2e-08 33.0 0.0 0.00028 20.9 0.0 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.6 EOO01794.1 - 4.6e-07 30.2 0.4 0.00093 19.6 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EOO01794.1 - 2.6e-06 26.9 2.1 0.027 14.4 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain AAA_29 PF13555.6 EOO01794.1 - 3.8e-05 23.4 0.1 0.061 13.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EOO01794.1 - 5.4e-05 23.6 0.0 0.1 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 EOO01794.1 - 9.6e-05 22.5 0.1 0.59 10.2 0.2 3.1 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 EOO01794.1 - 0.00011 22.1 0.1 1.7 8.5 0.1 3.4 2 1 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 EOO01794.1 - 0.00049 20.4 0.0 0.45 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain EF-hand_5 PF13202.6 EOO01794.1 - 0.0005 19.4 4.8 0.09 12.3 1.9 2.9 2 0 0 2 2 2 2 EF hand ABC_tran PF00005.27 EOO01794.1 - 0.0018 18.8 0.0 3.3 8.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter DUF3052 PF11253.8 EOO01794.1 - 0.0043 17.0 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3052) GTP_EFTU PF00009.27 EOO01794.1 - 0.0048 16.5 0.0 8.1 5.9 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain EF-hand_10 PF14788.6 EOO01794.1 - 0.0082 16.0 0.9 0.055 13.3 0.1 2.3 2 0 0 2 2 2 1 EF hand RNA_helicase PF00910.22 EOO01794.1 - 0.0086 16.5 0.0 0.42 11.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 EOO01794.1 - 0.01 15.6 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EOO01794.1 - 0.011 14.9 0.1 1.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) EF-hand_8 PF13833.6 EOO01794.1 - 0.014 15.2 2.9 3.6 7.5 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair AAA_28 PF13521.6 EOO01794.1 - 0.016 15.4 0.0 5 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 EOO01794.1 - 0.018 15.0 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 IIGP PF05049.13 EOO01794.1 - 0.025 13.6 0.1 0.77 8.8 0.1 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Viral_helicase1 PF01443.18 EOO01794.1 - 0.027 14.2 0.0 0.97 9.1 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Septin PF00735.18 EOO01794.1 - 0.047 13.0 0.0 0.26 10.5 0.0 2.0 2 0 0 2 2 2 0 Septin NACHT PF05729.12 EOO01794.1 - 0.072 13.0 0.1 3.3 7.6 0.0 2.8 3 0 0 3 3 2 0 NACHT domain AAA_7 PF12775.7 EOO01794.1 - 0.081 12.4 0.0 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 EOO01794.1 - 0.17 12.4 0.0 2.1 8.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EOO01794.1 - 0.18 11.2 0.0 7.9 5.9 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain PilJ_C PF18223.1 EOO01794.1 - 0.18 12.3 0.0 0.37 11.3 0.0 1.4 1 0 0 1 1 1 0 Pili PilJ C-terminal domain AAA_23 PF13476.6 EOO01794.1 - 0.21 12.1 0.1 21 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain zf-RING_2 PF13639.6 EOO01796.1 - 6.5e-11 42.4 5.2 9.7e-11 41.8 5.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 EOO01796.1 - 3.5e-07 30.2 0.8 5.9e-07 29.5 0.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EOO01796.1 - 8.5e-07 29.2 5.7 2.5e-06 27.7 5.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EOO01796.1 - 5.5e-05 22.9 6.8 0.00017 21.4 7.0 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EOO01796.1 - 0.00011 22.1 3.5 0.00016 21.6 2.4 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EOO01796.1 - 0.00022 21.0 3.5 0.00037 20.3 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EOO01796.1 - 0.00063 19.5 4.2 0.0017 18.2 4.0 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 EOO01796.1 - 0.0048 16.7 2.3 0.12 12.2 0.3 2.6 2 0 0 2 2 2 1 Rad50 zinc hook motif Prok-RING_4 PF14447.6 EOO01796.1 - 0.0052 16.6 7.6 0.066 13.1 2.2 2.3 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 EOO01796.1 - 0.014 15.3 3.5 0.025 14.5 0.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EOO01796.1 - 0.014 15.3 2.6 0.027 14.4 2.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 EOO01796.1 - 0.017 14.8 1.0 0.017 14.8 1.0 2.0 2 1 0 2 2 2 0 RING-like zinc finger Prok-RING_1 PF14446.6 EOO01796.1 - 0.055 13.4 3.6 0.66 10.0 0.4 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 EOO01796.1 - 0.073 12.9 5.3 0.35 10.7 5.5 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 EOO01796.1 - 0.082 13.2 3.6 6.9 7.1 0.2 2.7 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding FANCL_C PF11793.8 EOO01796.1 - 0.15 12.2 3.4 4 7.7 3.4 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain UBZ_FAAP20 PF15750.5 EOO01796.1 - 0.74 9.8 3.5 16 5.5 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger Zn-C2H2_12 PF18112.1 EOO01796.1 - 0.97 10.0 6.5 9.5 6.8 0.1 3.3 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C4_Topoisom PF01396.19 EOO01796.1 - 2.3 8.1 4.6 1.9 8.4 0.8 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-UDP PF14569.6 EOO01796.1 - 2.8 8.1 5.0 2.9 8.1 1.2 2.1 1 1 1 2 2 2 0 Zinc-binding RING-finger DUF1110 PF06533.12 EOO01797.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) Peptidase_M24 PF00557.24 EOO01799.1 - 3e-52 177.4 0.1 3.8e-52 177.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EOO01799.1 - 2.2e-39 133.9 0.0 3.4e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain TFA2_Winged_2 PF18121.1 EOO01800.1 - 9.4e-23 79.7 0.3 1.6e-22 78.9 0.3 1.4 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 EOO01800.1 - 3e-14 53.0 0.1 2.2e-13 50.3 0.0 2.4 3 0 0 3 3 3 1 TFIIE beta subunit core domain Polyoma_coat PF00718.20 EOO01800.1 - 0.038 13.3 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Polyomavirus coat protein HTH_11 PF08279.12 EOO01800.1 - 0.054 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 HTH domain DUF4777 PF16007.5 EOO01800.1 - 0.17 12.1 0.0 1.7 8.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4777) Pantoate_transf PF02548.15 EOO01801.1 - 9.3e-107 356.2 0.2 1.1e-106 356.0 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EOO01801.1 - 1.7e-10 40.8 0.1 2.9e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Mg_chelatase_C PF13335.6 EOO01801.1 - 0.16 12.6 0.0 0.35 11.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal Flavokinase PF01687.17 EOO01802.1 - 1.4e-34 118.7 0.0 1.6e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase MFS_1 PF07690.16 EOO01803.1 - 2.3e-37 128.7 32.2 2.7e-37 128.5 32.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EOO01803.1 - 7.7e-06 24.6 1.8 7.7e-06 24.6 1.8 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 EOO01803.1 - 0.00041 18.9 2.2 0.00076 18.0 0.9 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector Inositol_P PF00459.25 EOO01804.1 - 3.7e-51 174.2 2.4 1.1e-50 172.6 2.4 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family Fapy_DNA_glyco PF01149.24 EOO01805.1 - 3.9e-38 130.6 0.0 7.4e-38 129.7 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EOO01805.1 - 5.6e-20 71.1 0.0 1.1e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 EOO01805.1 - 0.00027 19.9 4.9 0.014 14.2 0.0 2.9 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) DUF4764 PF15961.5 EOO01805.1 - 0.44 9.2 9.8 0.62 8.7 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) zf-Nse PF11789.8 EOO01806.1 - 6.3e-22 77.2 0.1 1.2e-21 76.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EOO01806.1 - 0.00042 20.3 0.1 0.00076 19.5 0.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EOO01806.1 - 0.0038 17.0 0.1 0.0074 16.1 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 EOO01806.1 - 0.056 13.2 0.2 0.1 12.3 0.2 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger UQ_con PF00179.26 EOO01807.1 - 4.3e-36 123.7 0.1 5.2e-36 123.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pox_MCEL PF03291.16 EOO01808.1 - 1.8e-71 241.0 0.0 2.1e-47 161.9 0.0 2.3 1 1 1 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 EOO01808.1 - 2.4e-10 41.0 0.0 0.0001 22.9 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EOO01808.1 - 5.6e-10 39.8 0.0 0.00086 20.0 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EOO01808.1 - 4.1e-07 29.9 0.0 0.00049 19.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EOO01808.1 - 1.3e-06 28.9 0.1 0.069 13.8 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EOO01808.1 - 1.9e-05 24.6 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EOO01808.1 - 7e-05 22.1 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_9 PF08003.11 EOO01808.1 - 0.16 10.9 0.0 0.3 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Raftlin PF15250.6 EOO01808.1 - 0.2 10.4 0.0 0.2 10.4 0.0 1.9 2 0 0 2 2 2 0 Raftlin Ribosomal_L7Ae PF01248.26 EOO01809.1 - 4e-20 71.4 0.6 6.8e-20 70.6 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 EOO01809.1 - 0.022 13.8 0.2 0.027 13.5 0.2 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) PH PF00169.29 EOO01810.1 - 0.0006 20.3 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF2891 PF11199.8 EOO01810.1 - 0.09 11.7 0.1 0.16 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) SIL1 PF16782.5 EOO01810.1 - 0.092 11.9 1.5 0.097 11.9 0.4 1.4 2 0 0 2 2 2 0 Nucleotide exchange factor SIL1 Apolipoprotein PF01442.18 EOO01810.1 - 0.17 11.7 2.0 0.17 11.7 0.6 1.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain TSNAXIP1_N PF15739.5 EOO01810.1 - 0.25 11.7 1.8 0.62 10.5 0.8 2.1 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus p450 PF00067.22 EOO01811.1 - 7e-27 94.3 0.0 1.5e-23 83.3 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 PDZ_1 PF12812.7 EOO01811.1 - 0.1 12.7 0.0 0.56 10.2 0.0 2.1 2 0 0 2 2 2 0 PDZ-like domain DUF572 PF04502.13 EOO01812.1 - 3.8e-72 243.7 0.0 4.2e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) MukB_hinge PF16330.5 EOO01812.1 - 0.052 13.2 0.6 0.089 12.5 0.6 1.3 1 0 0 1 1 1 0 MukB hinge domain DUF1778 PF08681.11 EOO01812.1 - 0.06 13.3 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) NUC153 PF08159.12 EOO01813.1 - 4.7e-14 51.9 0.9 1e-13 50.8 0.9 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 EOO01813.1 - 1.6e-05 25.5 0.2 0.13 13.2 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO01813.1 - 0.00015 22.0 0.0 0.00047 20.4 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EOO01813.1 - 0.02 14.8 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A DSBA PF01323.20 EOO01814.1 - 8.5e-24 84.4 0.0 1.1e-23 84.1 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EOO01814.1 - 0.016 15.4 0.0 0.086 13.0 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.6 EOO01814.1 - 0.13 12.3 0.0 0.73 9.9 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin domain Cyt-b5 PF00173.28 EOO01815.1 - 6.3e-24 83.9 0.3 8.2e-24 83.5 0.3 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YqzH PF14164.6 EOO01815.1 - 0.031 14.3 0.7 0.066 13.3 0.7 1.5 1 0 0 1 1 1 0 YqzH-like protein Nup96 PF12110.8 EOO01816.1 - 1.5e-98 329.5 0.2 2.2e-98 329.0 0.2 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EOO01816.1 - 1.8e-52 177.4 0.0 3e-52 176.7 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EOO01816.1 - 2.6e-19 69.8 302.0 2.8e-08 34.5 41.4 9.7 4 2 6 10 10 10 6 Nucleoporin FG repeat region Peptidase_S10 PF00450.22 EOO01817.1 - 1e-68 232.7 0.1 1.6e-68 232.1 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase HLH PF00010.26 EOO01818.1 - 1.8e-16 59.8 0.1 6.5e-16 58.0 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain KRTAP PF11759.8 EOO01818.1 - 0.38 11.3 7.6 0.63 10.6 7.6 1.3 1 0 0 1 1 1 0 Keratin-associated matrix FBPase PF00316.20 EOO01819.1 - 1.2e-70 236.9 0.4 1.6e-70 236.5 0.4 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Transket_pyr PF02779.24 EOO01820.1 - 5.2e-42 143.5 0.0 8.6e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EOO01820.1 - 8e-34 116.2 0.0 1.5e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EOO01820.1 - 0.014 15.7 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II PHY PF00360.20 EOO01821.1 - 2e-30 105.4 0.0 4.1e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 EOO01821.1 - 1.7e-18 67.1 0.1 3.2e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EOO01821.1 - 1.1e-16 61.0 0.0 7.1e-16 58.4 0.0 2.4 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 EOO01821.1 - 8.7e-13 49.1 0.0 2.4e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 EOO01821.1 - 7.1e-12 45.2 0.9 2.8e-11 43.3 0.9 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 EOO01821.1 - 8.1e-09 36.1 0.0 2.8e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 EOO01821.1 - 0.00014 21.8 0.2 0.00043 20.2 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 EOO01821.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA PF00004.29 EOO01822.1 - 9.6e-17 61.6 0.0 1.5e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EOO01822.1 - 0.00014 22.2 0.9 0.0013 19.0 0.2 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EOO01822.1 - 0.00044 20.7 0.4 0.0015 18.9 0.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EOO01822.1 - 0.0011 18.9 0.2 0.0045 17.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EOO01822.1 - 0.018 14.7 0.5 0.04 13.6 0.3 1.7 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EOO01822.1 - 0.028 15.0 0.0 0.098 13.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EOO01822.1 - 0.045 13.5 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EOO01822.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EOO01822.1 - 0.087 12.6 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EOO01822.1 - 0.15 11.4 0.1 0.29 10.5 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EOO01822.1 - 0.23 11.7 0.6 1.2 9.4 0.1 2.0 1 1 1 2 2 2 0 AAA domain MFS_1 PF07690.16 EOO01823.1 - 1.1e-21 77.2 20.5 1.7e-21 76.5 20.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EOO01823.1 - 0.0019 17.1 3.6 0.0047 15.9 3.6 1.6 1 0 0 1 1 1 1 MFS_1 like family DUF4500 PF14937.6 EOO01823.1 - 0.15 12.1 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) DUF308 PF03729.13 EOO01823.1 - 1.9 8.8 9.9 2.3 8.6 4.7 3.2 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Thioredoxin PF00085.20 EOO01824.1 - 2.1e-05 24.5 0.0 3.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 EOO01824.1 - 0.011 15.5 0.4 0.015 15.0 0.3 1.4 1 1 0 1 1 1 0 Redoxin Thioredoxin_2 PF13098.6 EOO01824.1 - 0.016 15.7 0.0 3.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EOO01824.1 - 0.16 11.8 0.0 0.49 10.2 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin Mannosidase_ig PF17786.1 EOO01825.1 - 0.051 14.2 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Mannosidase Ig/CBM-like domain Peptidase_S64 PF08192.11 EOO01825.1 - 0.09 11.2 0.3 5.4 5.4 0.0 2.7 2 1 0 3 3 3 0 Peptidase family S64 Slu7 PF11708.8 EOO01827.1 - 1.1e-79 268.0 22.0 1.1e-79 268.0 22.0 2.8 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.23 EOO01827.1 - 0.0017 18.3 4.8 0.0032 17.5 4.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EOO01827.1 - 0.02 14.6 0.4 0.039 13.7 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 EOO01827.1 - 0.53 10.2 5.0 1.3 8.9 5.0 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF4616 PF15394.6 EOO01828.1 - 0.12 11.3 0.8 0.12 11.4 0.1 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4616) MMM1 PF10296.9 EOO01829.1 - 4.4e-09 35.8 0.3 2.1e-08 33.6 0.1 1.9 1 1 1 2 2 2 1 Maintenance of mitochondrial morphology protein 1 DNA_pol_B PF00136.21 EOO01835.1 - 6.8e-105 351.4 0.0 8.1e-105 351.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 EOO01835.1 - 9.3e-17 61.3 3.2 9.3e-17 61.3 3.2 2.2 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DZR PF12773.7 EOO01835.1 - 0.0038 17.2 2.7 0.0083 16.1 2.7 1.5 1 0 0 1 1 1 1 Double zinc ribbon DNA_pol_B_2 PF03175.13 EOO01835.1 - 0.06 12.2 0.1 0.091 11.6 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral DUF2116 PF09889.9 EOO01835.1 - 0.12 12.3 4.9 0.68 10.0 0.7 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) CEBP_ZZ PF16366.5 EOO01835.1 - 0.26 11.5 1.5 21 5.4 0.2 2.5 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Zn_ribbon_17 PF17120.5 EOO01835.1 - 0.46 10.2 2.7 0.36 10.5 0.7 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type NACHT_N PF17100.5 EOO01836.1 - 1.4e-14 54.5 0.0 2.6e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 EOO01836.1 - 2.7e-10 40.7 0.3 9.6e-09 35.7 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EOO01836.1 - 2.7e-06 27.8 1.2 0.00091 19.8 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EOO01836.1 - 8.7e-06 25.9 0.0 0.022 15.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EOO01836.1 - 0.0004 20.7 0.2 0.78 10.3 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EOO01836.1 - 0.00041 20.6 0.3 2.8 8.8 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Dioxygenase_C PF00775.21 EOO01837.1 - 7.3e-08 32.1 0.0 9.1e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Spc7 PF08317.11 EOO01838.1 - 0.0034 16.3 27.7 0.016 14.1 5.2 3.0 2 1 1 3 3 3 2 Spc7 kinetochore protein FlxA PF14282.6 EOO01838.1 - 0.0063 16.5 14.6 0.033 14.2 8.2 2.9 3 1 0 3 3 2 1 FlxA-like protein LMBR1 PF04791.16 EOO01838.1 - 0.026 13.4 5.5 0.036 13.0 5.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Atg14 PF10186.9 EOO01838.1 - 0.028 13.5 18.3 0.37 9.8 1.6 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 EOO01838.1 - 0.036 14.4 3.6 0.036 14.4 3.6 2.9 3 1 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MPS2 PF17060.5 EOO01838.1 - 0.046 13.0 9.2 0.062 12.6 9.2 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 Spc24 PF08286.11 EOO01838.1 - 0.07 13.4 16.1 0.054 13.7 4.5 3.2 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Bacillus_HBL PF05791.11 EOO01838.1 - 0.11 12.3 9.6 0.14 12.0 2.0 2.6 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ADIP PF11559.8 EOO01838.1 - 0.12 12.5 15.4 1.5 8.9 0.4 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.6 EOO01838.1 - 0.16 10.6 10.0 0.23 10.1 10.0 1.2 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 EOO01838.1 - 0.25 10.6 11.9 0.52 9.6 11.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3138 PF11336.8 EOO01838.1 - 0.29 9.7 0.5 0.63 8.6 0.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Laminin_II PF06009.12 EOO01838.1 - 0.54 10.3 13.0 1.2 9.1 1.5 2.7 2 1 1 3 3 3 0 Laminin Domain II NPV_P10 PF05531.12 EOO01838.1 - 0.6 10.6 7.0 3.2 8.3 0.1 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PAXX PF15384.6 EOO01838.1 - 0.71 9.5 9.5 1.4 8.5 0.3 2.4 1 1 0 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 LPP PF04728.13 EOO01838.1 - 0.81 10.1 4.1 16 6.0 2.1 3.3 3 0 0 3 3 3 0 Lipoprotein leucine-zipper SlyX PF04102.12 EOO01838.1 - 0.97 10.1 20.8 0.56 10.9 6.0 3.9 4 1 1 5 5 3 0 SlyX Fez1 PF06818.15 EOO01838.1 - 1.2 9.6 20.2 6.3 7.2 20.1 2.1 1 1 0 1 1 1 0 Fez1 YlqD PF11068.8 EOO01838.1 - 1.5 9.2 20.2 0.19 12.1 6.6 2.6 3 0 0 3 3 2 0 YlqD protein HemX PF04375.14 EOO01838.1 - 1.9 7.7 14.0 1.8 7.7 10.5 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase IFT20 PF14931.6 EOO01838.1 - 2 8.6 14.7 0.4 10.9 7.6 2.5 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 PRKG1_interact PF15898.5 EOO01838.1 - 2 9.4 24.0 0.47 11.4 9.3 2.7 3 0 0 3 3 2 0 cGMP-dependent protein kinase interacting domain DUF948 PF06103.11 EOO01838.1 - 2.2 8.6 6.8 1.4 9.2 0.3 2.5 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) OmpH PF03938.14 EOO01838.1 - 2.9 8.2 25.1 3.5 8.0 4.6 2.5 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) TolA_bind_tri PF16331.5 EOO01838.1 - 3 8.0 14.7 5.5 7.1 10.9 2.8 1 1 0 2 2 2 0 TolA binding protein trimerisation Exonuc_VII_L PF02601.15 EOO01838.1 - 3.2 7.2 12.8 14 5.1 12.8 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF641 PF04859.12 EOO01838.1 - 3.2 8.1 13.9 64 3.9 11.9 2.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) USP8_interact PF08941.10 EOO01838.1 - 3.3 7.5 6.2 8.6 6.1 1.7 2.4 2 0 0 2 2 2 0 USP8 interacting DUF4055 PF13264.6 EOO01838.1 - 4.2 7.5 5.8 2.8 8.1 2.5 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4055) MerR-DNA-bind PF09278.11 EOO01838.1 - 4.3 7.9 11.9 7.8 7.1 0.4 3.1 2 0 0 2 2 2 0 MerR, DNA binding V_ATPase_I PF01496.19 EOO01838.1 - 6.1 4.6 6.0 9.6 4.0 6.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 EOO01838.1 - 6.4 6.8 9.3 8.1 6.5 0.6 2.8 3 1 0 3 3 2 0 Protein of unknown function (DUF1664) TEX13 PF15186.6 EOO01838.1 - 7.8 6.2 12.4 2.9 7.6 7.9 2.2 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family ERM PF00769.19 EOO01838.1 - 7.9 6.2 27.7 1.2 8.9 14.8 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 EOO01838.1 - 9.5 6.2 28.4 0.27 11.3 12.8 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PA PF02225.22 EOO01839.1 - 7.5e-11 41.9 0.0 1.9e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 PA domain S4 PF01479.25 EOO01840.1 - 2.4e-12 46.4 0.9 2.4e-12 46.4 0.9 2.6 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EOO01840.1 - 9.2e-06 26.5 0.1 1.8e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 EOO01840.1 - 0.094 12.9 0.4 3 8.0 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation SBP_bac_11 PF13531.6 EOO01842.1 - 0.01 15.6 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein DUF1759 PF03564.15 EOO01842.1 - 0.16 11.9 0.3 0.5 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) MFS_1 PF07690.16 EOO01844.1 - 2.5e-34 118.8 31.6 2.3e-26 92.5 9.1 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO01844.1 - 1.2e-13 50.7 7.7 1.2e-13 50.7 7.7 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EOO01844.1 - 0.0084 14.6 2.8 0.016 13.7 2.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_S7 PF00949.21 EOO01846.1 - 0.007 16.2 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease HMGL-like PF00682.19 EOO01847.1 - 2.8e-21 76.3 0.0 1.1e-20 74.3 0.0 1.8 1 1 0 1 1 1 1 HMGL-like DUF2701 PF10857.8 EOO01847.1 - 0.11 12.5 0.1 15 5.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2701) Cupin_2 PF07883.11 EOO01848.1 - 1.1e-14 53.9 0.6 1.8e-10 40.4 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EOO01848.1 - 1.2e-05 24.9 0.0 0.0012 18.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 EOO01848.1 - 0.00065 19.6 0.3 0.0023 17.8 0.1 1.9 2 0 0 2 2 2 1 AraC-like ligand binding domain GatD_N PF18195.1 EOO01848.1 - 0.0046 16.2 0.0 0.95 8.8 0.0 2.6 2 0 0 2 2 2 2 GatD N-terminal domain Ppnp PF06865.11 EOO01848.1 - 0.005 17.2 0.0 0.027 14.9 0.0 2.1 2 0 0 2 2 2 1 Pyrimidine/purine nucleoside phosphorylase Cupin_1 PF00190.22 EOO01848.1 - 0.016 14.8 0.5 0.096 12.3 0.0 2.4 2 1 1 3 3 3 0 Cupin Cupin_4 PF08007.12 EOO01848.1 - 0.095 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Ribosomal_L37e PF01907.19 EOO01849.1 - 8.7e-28 96.3 13.1 1.3e-27 95.7 13.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 EOO01849.1 - 0.005 16.8 1.7 0.0076 16.3 1.7 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 EOO01849.1 - 0.082 12.7 2.1 7 6.5 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 EOO01849.1 - 0.13 12.3 1.1 0.18 11.9 1.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4_2 PF13923.6 EOO01849.1 - 0.91 9.4 5.0 2.1 8.3 5.3 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BBE PF08031.12 EOO01850.1 - 9.9e-05 22.4 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like CBM64 PF18666.1 EOO01850.1 - 0.013 15.6 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 64 FAD_binding_3 PF01494.19 EOO01851.1 - 5e-19 68.8 0.0 9.5e-19 67.8 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EOO01851.1 - 2.9e-10 40.3 1.9 0.00017 21.3 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EOO01851.1 - 1.3e-06 27.9 1.1 0.013 14.8 0.9 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EOO01851.1 - 5.3e-06 25.8 2.9 7.9e-06 25.2 2.9 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EOO01851.1 - 3.1e-05 23.5 0.0 3.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EOO01851.1 - 0.00011 22.3 0.3 0.00035 20.7 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EOO01851.1 - 0.00012 22.5 0.2 0.026 15.1 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EOO01851.1 - 0.00014 20.7 0.9 0.0012 17.6 0.8 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EOO01851.1 - 0.00027 20.2 0.1 0.0013 17.9 0.5 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A SE PF08491.10 EOO01851.1 - 0.0052 15.9 0.0 0.019 14.0 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.12 EOO01851.1 - 0.015 14.4 0.3 0.065 12.3 0.3 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EOO01851.1 - 0.063 12.5 0.9 0.099 11.9 0.9 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 EOO01851.1 - 0.17 11.1 0.0 0.68 9.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GST_N PF02798.20 EOO01852.1 - 2.3e-18 66.3 0.0 3.1e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EOO01852.1 - 7.1e-16 58.4 0.0 9.2e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EOO01852.1 - 3.6e-13 49.6 0.0 4.6e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Lipase_GDSL_2 PF13472.6 EOO01853.1 - 2.7e-20 73.5 0.2 5.2e-20 72.6 0.2 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EOO01853.1 - 1e-12 48.5 0.0 1.6e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EOO01853.1 - 0.021 15.0 0.0 0.048 13.8 0.0 1.6 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF3562 PF12085.8 EOO01853.1 - 0.051 13.2 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) MAS20 PF02064.15 EOO01854.1 - 0.066 13.3 0.0 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 MAS20 protein import receptor rhaM PF05336.13 EOO01855.1 - 3.1e-36 123.7 0.1 4e-36 123.4 0.1 1.1 1 0 0 1 1 1 1 L-rhamnose mutarotase DUF1295 PF06966.12 EOO01856.1 - 1.1e-11 44.7 0.2 1.6e-11 44.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 EOO01856.1 - 8.3e-06 24.8 1.0 1.4e-05 24.1 1.0 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 EOO01856.1 - 0.0019 18.2 0.3 0.0029 17.6 0.3 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase HAP1_N PF04849.13 EOO01857.1 - 0.26 10.4 42.5 0.16 11.2 2.5 4.9 3 1 2 5 5 5 0 HAP1 N-terminal conserved region ZapB PF06005.12 EOO01857.1 - 6.6 7.3 45.8 0.11 12.9 5.3 5.7 5 1 0 5 5 5 0 Cell division protein ZapB Ribosomal_L21e PF01157.18 EOO01859.1 - 4.8e-47 158.0 5.2 4.8e-47 158.0 5.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e DUF5486 PF17588.2 EOO01859.1 - 0.0086 15.9 1.2 0.19 11.6 0.1 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5486) zf-TFIIB PF13453.6 EOO01860.1 - 0.03 13.7 0.1 0.06 12.7 0.1 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger NPR3 PF03666.13 EOO01861.1 - 0.35 9.6 4.4 0.59 8.9 4.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ORC6 PF05460.13 EOO01861.1 - 1.1 8.5 11.7 0.24 10.7 8.0 1.7 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) QWRF PF04484.12 EOO01861.1 - 2.4 7.9 11.8 3.4 7.3 11.8 1.2 1 0 0 1 1 1 0 QWRF family Aminotran_4 PF01063.19 EOO01862.1 - 1.4e-37 129.7 0.0 1.7e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Aldo_ket_red PF00248.21 EOO01864.1 - 6.9e-30 104.2 0.0 8.8e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ABC_membrane PF00664.23 EOO01865.1 - 7.1e-19 68.5 1.8 9.6e-19 68.1 1.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region LPMO_10 PF03067.15 EOO01866.1 - 0.0046 17.6 0.0 0.011 16.4 0.0 1.7 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 EOO01866.1 - 0.007 16.3 0.0 0.016 15.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short_C2 PF13561.6 EOO01867.1 - 1.9e-54 184.7 0.3 2.8e-54 184.2 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO01867.1 - 2.6e-45 154.3 2.9 3.2e-45 154.0 2.9 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO01867.1 - 6.7e-12 45.7 0.3 8.8e-12 45.3 0.3 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 EOO01867.1 - 0.00055 19.9 0.7 0.53 10.3 0.2 2.2 1 1 1 2 2 2 2 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.19 EOO01867.1 - 0.045 13.1 0.3 0.08 12.3 0.3 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1372 PF07116.11 EOO01867.1 - 0.099 12.8 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) HSP70 PF00012.20 EOO01868.1 - 5.1e-61 206.6 18.8 1.3e-58 198.7 0.1 3.5 3 1 1 4 4 4 2 Hsp70 protein MreB_Mbl PF06723.13 EOO01868.1 - 0.0014 17.5 0.1 0.0046 15.8 0.1 1.8 1 0 0 1 1 1 1 MreB/Mbl protein YcbB PF08664.10 EOO01868.1 - 0.085 12.9 0.3 0.46 10.5 0.0 2.4 2 0 0 2 2 2 0 YcbB domain DUF1192 PF06698.11 EOO01868.1 - 1.1 9.4 4.7 22 5.2 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Kinesin_assoc PF16183.5 EOO01868.1 - 8.8 6.4 12.8 5.7 7.0 1.0 3.8 3 1 0 3 3 3 0 Kinesin-associated RHS_repeat PF05593.14 EOO01869.1 - 7.4e-14 51.9 35.5 0.0077 16.7 0.1 13.1 12 1 0 12 12 12 5 RHS Repeat VCBS PF13517.6 EOO01869.1 - 8.3e-08 32.7 7.2 0.35 11.5 0.2 5.2 3 0 0 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SpvB PF03534.13 EOO01869.1 - 1.4e-07 31.0 0.4 0.0082 15.4 0.1 2.7 2 0 0 2 2 2 2 Salmonella virulence plasmid 65kDa B protein FG-GAP PF01839.23 EOO01869.1 - 0.0012 18.9 0.4 0.077 13.2 0.0 3.2 2 0 0 2 2 2 1 FG-GAP repeat Asp PF00026.23 EOO01870.1 - 3.4e-64 217.3 0.1 3.9e-64 217.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EOO01870.1 - 9.4e-10 39.0 0.4 2.1e-07 31.4 0.1 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EOO01870.1 - 1e-05 26.0 0.3 0.0067 17.0 0.2 3.1 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 EOO01870.1 - 0.0016 18.2 0.0 0.0063 16.3 0.0 2.0 2 1 1 3 3 3 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EOO01870.1 - 0.0018 18.8 0.0 0.27 11.8 0.0 2.7 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease B1 PF02246.15 EOO01870.1 - 0.17 11.9 0.6 0.7 10.0 0.2 2.2 2 0 0 2 2 2 0 Protein L b1 domain ERG4_ERG24 PF01222.17 EOO01871.1 - 7.5e-112 374.2 20.4 1.3e-72 244.9 8.9 2.0 1 1 1 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family Beta-lactamase PF00144.24 EOO01872.1 - 6.7e-47 160.3 0.0 8.4e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Alpha-amylase PF00128.24 EOO01873.1 - 3e-36 125.7 0.0 5.1e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EOO01873.1 - 0.0041 17.2 0.0 0.013 15.6 0.0 1.8 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain UPF0258 PF06789.12 EOO01873.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Aconitase PF00330.20 EOO01874.1 - 1.1e-75 255.5 1.0 9.2e-74 249.1 1.0 2.2 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EOO01874.1 - 8.4e-16 58.5 0.0 1.9e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain AIP3 PF03915.13 EOO01875.1 - 3.1e-161 537.1 9.0 3.1e-161 537.1 9.0 1.8 2 0 0 2 2 2 1 Actin interacting protein 3 Lectin_N PF03954.14 EOO01875.1 - 0.019 14.7 0.3 0.019 14.7 0.3 3.6 4 0 0 4 4 4 0 Hepatic lectin, N-terminal domain ISG65-75 PF11727.8 EOO01875.1 - 0.043 13.0 2.6 4 6.6 0.1 2.6 2 0 0 2 2 2 0 Invariant surface glycoprotein RasGAP_C PF03836.15 EOO01875.1 - 0.077 13.1 6.6 0.59 10.3 0.4 4.2 5 0 0 5 5 5 0 RasGAP C-terminus DUF2868 PF11067.8 EOO01875.1 - 0.13 11.8 0.7 0.3 10.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) GNVR PF13807.6 EOO01875.1 - 0.41 10.6 1.6 5 7.1 0.2 2.6 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase Spore_III_AB PF09548.10 EOO01875.1 - 0.98 9.5 5.7 0.2 11.8 0.2 2.5 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Ribosomal_S13 PF00416.22 EOO01875.1 - 7.6 6.9 7.0 0.77 10.2 1.0 2.5 2 1 0 2 2 2 0 Ribosomal protein S13/S18 MFS_1 PF07690.16 EOO01877.1 - 4.7e-34 117.9 36.6 7.1e-34 117.3 36.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily OSTbeta PF15048.6 EOO01877.1 - 0.21 11.7 0.4 17 5.6 0.0 2.3 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein zf-CSL PF05207.13 EOO01878.1 - 3.3e-22 78.0 1.2 4.2e-22 77.6 1.2 1.2 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 EOO01878.1 - 8.6e-06 25.8 0.4 1.4e-05 25.1 0.4 1.4 1 0 0 1 1 1 1 Zinc ribbon domain Terminase_GpA PF05876.12 EOO01878.1 - 0.041 12.4 0.1 0.05 12.2 0.1 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Glyco_hydro_31 PF01055.26 EOO01879.1 - 1.6e-110 370.3 0.4 2.3e-110 369.8 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EOO01879.1 - 1.9e-05 24.9 0.1 0.00013 22.2 0.1 2.4 1 1 0 1 1 1 1 Galactose mutarotase-like A_deaminase PF00962.22 EOO01880.1 - 7.4e-23 81.4 0.0 8.6e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase SlyX PF04102.12 EOO01881.1 - 0.0019 18.8 1.5 0.0019 18.8 1.5 2.3 3 0 0 3 3 3 1 SlyX DUF16 PF01519.16 EOO01881.1 - 0.007 16.8 1.9 0.013 16.0 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF16 TACC_C PF05010.14 EOO01881.1 - 0.0084 15.9 0.6 0.0084 15.9 0.6 1.9 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF2076 PF09849.9 EOO01881.1 - 0.011 15.8 10.7 0.011 15.8 10.7 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) ATG16 PF08614.11 EOO01881.1 - 0.028 14.6 2.1 0.028 14.6 2.1 2.9 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) XhlA PF10779.9 EOO01881.1 - 0.034 14.4 2.3 0.064 13.5 2.3 1.4 1 0 0 1 1 1 0 Haemolysin XhlA SOG2 PF10428.9 EOO01881.1 - 0.11 11.7 16.6 0.13 11.4 16.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Vac7 PF12751.7 EOO01881.1 - 2.6 7.4 13.3 3.3 7.1 13.3 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Hydin_ADK PF17213.3 EOO01881.1 - 7.6 6.8 12.6 2.6 8.3 7.3 2.1 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain SKA1 PF07160.12 EOO01881.1 - 7.9 6.3 15.9 0.069 13.0 1.7 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Aldo_ket_red PF00248.21 EOO01882.1 - 1.9e-71 240.7 0.0 2.1e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SGL PF08450.12 EOO01883.1 - 2.9e-24 86.0 1.1 8.5e-24 84.5 1.1 1.9 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EOO01883.1 - 6.5e-05 23.0 0.0 0.0018 18.4 0.0 2.6 1 1 1 2 2 2 1 Arylesterase Str_synth PF03088.16 EOO01883.1 - 9e-05 22.5 0.0 0.00048 20.2 0.0 2.2 1 1 0 1 1 1 1 Strictosidine synthase LsmAD PF06741.13 EOO01885.1 - 1.8e-27 95.7 2.6 1.8e-27 95.7 2.6 2.3 2 0 0 2 2 2 1 LsmAD domain AA_permease PF00324.21 EOO01887.1 - 2.9e-72 243.8 27.2 3.5e-72 243.5 27.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EOO01887.1 - 1.4e-19 70.2 29.9 1.8e-19 69.9 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease Synaptobrevin PF00957.21 EOO01887.1 - 0.47 10.3 0.1 0.47 10.3 0.1 2.7 3 0 0 3 3 3 0 Synaptobrevin RseC_MucC PF04246.12 EOO01887.1 - 3.9 7.4 5.9 26 4.7 0.5 2.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2207 PF09972.9 EOO01887.1 - 7 5.3 12.5 1.5 7.5 1.9 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) FAD_binding_3 PF01494.19 EOO01888.1 - 5.8e-21 75.1 0.1 3.1e-12 46.4 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 EOO01888.1 - 1.8e-05 24.5 0.2 0.0018 17.9 0.0 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 EOO01888.1 - 0.00033 19.8 0.0 0.011 14.8 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 EOO01888.1 - 0.00075 19.7 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EOO01888.1 - 0.00091 18.5 0.0 0.017 14.3 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EOO01888.1 - 0.0063 15.6 0.1 0.034 13.2 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 EOO01888.1 - 0.0065 15.2 0.0 0.012 14.3 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EOO01888.1 - 0.0073 16.9 0.1 0.07 13.7 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EOO01888.1 - 0.037 13.7 0.1 0.13 11.9 0.0 1.9 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 EOO01888.1 - 0.042 12.7 0.0 0.087 11.7 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase Dak2 PF02734.17 EOO01888.1 - 0.043 13.7 0.4 0.075 12.9 0.4 1.3 1 0 0 1 1 1 0 DAK2 domain 3-alpha PF03475.14 EOO01888.1 - 0.27 11.1 0.9 7.7 6.5 0.1 2.6 2 0 0 2 2 2 0 3-alpha domain Fungal_trans_2 PF11951.8 EOO01889.1 - 1.9e-58 198.1 0.0 2.6e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EOO01889.1 - 3.1e-06 27.2 9.0 5.9e-06 26.3 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kelch_4 PF13418.6 EOO01890.1 - 5.1e-19 68.0 3.6 1.5e-06 28.1 0.0 3.3 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_1 PF01344.25 EOO01890.1 - 5.5e-17 61.1 2.2 2.4e-09 36.6 0.3 3.3 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 EOO01890.1 - 2.3e-16 59.4 2.4 1.1e-08 35.1 0.7 3.3 2 1 1 3 3 3 3 Kelch motif Kelch_3 PF13415.6 EOO01890.1 - 1.6e-15 56.9 2.4 4.6e-07 30.0 0.1 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EOO01890.1 - 5.6e-15 54.9 1.6 0.0003 20.7 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 EOO01890.1 - 2.2e-14 52.8 2.2 6.1e-06 26.0 0.9 3.5 3 0 0 3 3 3 3 Kelch motif DUF5500 PF17604.2 EOO01890.1 - 0.041 14.0 0.0 0.25 11.4 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5500) Takusan PF04822.13 EOO01890.1 - 1.1 9.2 12.3 0.064 13.1 1.4 3.3 3 1 0 3 3 3 0 Takusan betaPIX_CC PF16523.5 EOO01890.1 - 2.9 7.8 10.8 0.41 10.5 0.9 3.1 3 0 0 3 3 3 0 betaPIX coiled coil Raptor_N PF14538.6 EOO01891.1 - 3e-64 215.4 0.0 4.5e-64 214.8 0.0 1.3 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain tRNA-synt_2 PF00152.20 EOO01892.1 - 2.7e-12 46.4 0.0 3.8e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EOO01892.1 - 0.00044 20.2 0.0 0.00072 19.5 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Nup160 PF11715.8 EOO01893.1 - 0.0039 15.9 0.0 0.0039 15.9 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EOO01893.1 - 0.005 17.1 0.0 0.94 9.8 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EOO01893.1 - 0.0079 17.0 0.7 0.76 10.8 0.2 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat FA_desaturase PF00487.24 EOO01894.1 - 8.4e-27 94.6 19.9 1.3e-26 94.0 19.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EOO01894.1 - 2e-18 65.6 0.3 3.9e-18 64.6 0.3 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) HhH-GPD PF00730.25 EOO01895.1 - 2.5e-15 56.9 0.0 3.1e-14 53.3 0.0 2.2 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Ndc1_Nup PF09531.10 EOO01895.1 - 0.34 9.5 5.3 0.42 9.2 5.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4646 PF15496.6 EOO01896.1 - 0.013 16.1 0.3 0.073 13.7 0.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4646) DUF508 PF04370.12 EOO01896.1 - 0.043 13.6 0.5 0.089 12.5 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Latarcin PF10279.9 EOO01896.1 - 1.4 9.4 6.2 4.3 7.8 6.2 1.9 1 0 0 1 1 1 0 Latarcin precursor Nucleopor_Nup85 PF07575.13 EOO01897.1 - 2.1e-08 33.2 0.1 4.3e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Nup85 Nucleoporin PBP1_TM PF14812.6 EOO01897.1 - 3.3 8.2 13.1 0.03 14.7 3.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_11 PF08241.12 EOO01898.1 - 3.3e-08 34.0 0.0 4.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EOO01898.1 - 5e-06 26.4 0.0 1e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO01898.1 - 1.2e-05 25.9 0.0 1.7e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO01898.1 - 0.00011 22.9 0.0 0.00014 22.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO01898.1 - 0.0012 18.7 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EOO01898.1 - 0.013 14.8 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family G-patch PF01585.23 EOO01899.1 - 9.8e-12 44.6 0.2 9.8e-12 44.6 0.2 1.8 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.22 EOO01899.1 - 0.0026 17.6 0.1 0.0054 16.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MtrG PF04210.13 EOO01899.1 - 0.32 10.9 1.0 0.73 9.7 1.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Nucleo_P87 PF07267.11 EOO01899.1 - 2.3 7.0 6.8 3.5 6.4 5.8 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Amino_oxidase PF01593.24 EOO01900.1 - 2.6e-59 201.7 0.0 3e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EOO01900.1 - 1.3e-13 50.9 0.4 3e-13 49.8 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EOO01900.1 - 1.6e-07 31.0 0.1 2.4e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EOO01900.1 - 9.3e-07 28.7 0.1 1.6e-06 27.9 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EOO01900.1 - 6.3e-06 25.5 1.7 8e-06 25.2 1.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EOO01900.1 - 1.1e-05 24.8 2.2 0.085 12.1 0.1 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EOO01900.1 - 3.2e-05 22.8 0.2 6.2e-05 21.9 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EOO01900.1 - 4.6e-05 23.9 0.1 0.0001 22.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EOO01900.1 - 5e-05 22.7 0.3 0.00012 21.4 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EOO01900.1 - 0.00024 20.5 0.1 0.00036 19.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EOO01900.1 - 0.0012 18.2 0.1 0.0019 17.5 0.1 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EOO01900.1 - 0.0012 18.0 0.3 0.0022 17.2 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EOO01900.1 - 0.059 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EOO01900.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ecm33 PF12454.8 EOO01901.1 - 1.6e-11 44.1 4.3 4.8e-11 42.6 4.3 1.9 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 EOO01901.1 - 0.00043 20.4 3.6 2.7 8.1 0.0 4.6 1 1 3 4 4 4 2 Receptor L domain SLAIN PF15301.6 EOO01901.1 - 0.42 9.8 2.9 0.53 9.5 0.1 2.0 2 0 0 2 2 2 0 SLAIN motif-containing family Aldo_ket_red PF00248.21 EOO01902.1 - 1.2e-40 139.6 0.0 1.2e-37 129.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Amino_oxidase PF01593.24 EOO01903.1 - 3.6e-51 174.9 0.0 2.4e-50 172.1 0.0 2.2 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase IF-2B PF01008.17 EOO01903.1 - 2.2e-42 145.2 0.0 6.1e-42 143.8 0.0 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family NAD_binding_8 PF13450.6 EOO01903.1 - 9e-14 51.5 0.9 2.1e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EOO01903.1 - 3.7e-05 23.1 0.0 0.00021 20.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EOO01903.1 - 0.0033 17.4 0.4 0.46 10.5 0.1 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EOO01903.1 - 0.0046 16.2 0.0 0.013 14.7 0.0 1.7 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EOO01903.1 - 0.0082 15.8 0.1 0.03 13.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EOO01903.1 - 0.013 16.0 0.2 0.013 16.0 0.2 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EOO01903.1 - 0.024 13.7 0.2 0.024 13.7 0.2 2.4 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EOO01903.1 - 0.031 13.0 0.2 0.14 10.8 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 EOO01903.1 - 0.039 13.2 1.1 0.055 12.7 0.5 1.5 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 EOO01903.1 - 0.12 12.3 0.1 0.41 10.5 0.1 2.0 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EOO01903.1 - 0.46 9.7 0.0 0.46 9.7 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Aldo_ket_red PF00248.21 EOO01904.1 - 8.7e-69 231.9 0.0 9.7e-69 231.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_15 PF00723.21 EOO01904.1 - 0.061 12.1 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 PHP_C PF13263.6 EOO01904.1 - 0.13 12.0 0.0 3.5 7.4 0.0 2.5 2 0 0 2 2 2 0 PHP-associated Acetyltransf_1 PF00583.25 EOO01905.1 - 4.5e-14 52.7 0.1 8.8e-14 51.8 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EOO01905.1 - 8.7e-08 32.2 0.2 1.8e-07 31.2 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EOO01905.1 - 2.5e-07 30.6 0.1 4.5e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EOO01905.1 - 4.3e-06 27.0 0.0 9.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EOO01905.1 - 0.0039 17.3 0.1 0.0076 16.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2052 PF09747.9 EOO01905.1 - 0.0043 17.2 0.3 0.0062 16.7 0.3 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Acetyltransf_15 PF17013.5 EOO01905.1 - 0.069 12.6 0.2 0.085 12.3 0.2 1.3 1 1 0 1 1 1 0 Putative acetyl-transferase zf-CCHC PF00098.23 EOO01906.1 - 1.9e-65 214.2 118.7 5.4e-07 29.4 1.4 13.4 13 1 0 13 13 13 12 Zinc knuckle zf-CCHC_4 PF14392.6 EOO01906.1 - 1.3e-10 40.8 69.4 0.078 12.7 0.2 12.3 12 1 0 12 12 12 9 Zinc knuckle zf-CCHC_2 PF13696.6 EOO01906.1 - 2.5e-08 33.6 103.3 0.027 14.3 0.2 12.9 13 0 0 13 13 13 8 Zinc knuckle zf-C2H2_10 PF16588.5 EOO01906.1 - 0.0036 17.0 1.5 0.0036 17.0 1.5 11.3 12 0 0 12 12 12 4 C2H2 zinc-finger zf-CCHC_3 PF13917.6 EOO01906.1 - 0.015 15.3 90.0 0.095 12.7 0.7 12.1 4 4 8 12 12 12 0 Zinc knuckle zf-CCHC_6 PF15288.6 EOO01906.1 - 0.16 11.8 0.2 0.16 11.8 0.2 12.0 10 2 2 12 12 12 0 Zinc knuckle AMP-binding PF00501.28 EOO01907.1 - 6.3e-89 298.5 0.0 7.4e-89 298.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EOO01907.1 - 1.4e-17 64.4 0.0 3.5e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 EOO01907.1 - 0.00024 20.1 0.0 0.0016 17.4 0.0 2.0 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 EOO01907.1 - 0.022 14.8 0.0 0.064 13.3 0.0 1.8 1 0 0 1 1 1 0 RTX C-terminal domain YCII PF03795.14 EOO01908.1 - 1.3e-08 35.1 0.0 1.6e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain KH_7 PF17214.3 EOO01908.1 - 0.076 13.0 0.0 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 KH domain Acyl-CoA_dh_1 PF00441.24 EOO01909.1 - 2.1e-33 115.6 0.3 3.5e-33 114.9 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 EOO01909.1 - 7.6e-20 70.8 0.4 1.6e-19 69.8 0.1 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 EOO01909.1 - 3.2e-11 43.3 0.0 6e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EOO01909.1 - 4.9e-08 33.6 0.0 1.1e-07 32.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EOO01909.1 - 0.00017 21.8 0.0 0.00057 20.2 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF952 PF06108.12 EOO01910.1 - 3.6e-23 81.4 0.0 5e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) UCH PF00443.29 EOO01911.1 - 1.3e-40 139.5 0.0 2.2e-40 138.8 0.0 1.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EOO01911.1 - 1.7e-07 31.2 0.0 3.3e-06 26.9 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2408 PF10303.9 EOO01912.1 - 1.1e-42 145.8 3.8 4.8e-26 91.9 0.0 5.2 2 2 2 4 4 4 4 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.6 EOO01912.1 - 0.032 14.7 3.3 1.1 9.7 0.3 4.2 3 1 1 4 4 4 0 Snapin/Pallidin COG6 PF06419.11 EOO01912.1 - 0.039 12.2 2.0 0.072 11.3 0.2 2.2 1 1 0 2 2 2 0 Conserved oligomeric complex COG6 TMF_TATA_bd PF12325.8 EOO01912.1 - 0.064 13.5 1.0 0.2 11.9 0.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.12 EOO01912.1 - 0.23 11.9 3.5 25 5.4 0.0 4.5 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein CorA PF01544.18 EOO01912.1 - 0.85 8.9 4.0 0.56 9.5 0.3 2.0 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Anp1 PF03452.14 EOO01913.1 - 2.1e-108 361.7 0.1 2.7e-108 361.4 0.1 1.1 1 0 0 1 1 1 1 Anp1 WD40 PF00400.32 EOO01914.1 - 2.2e-16 59.9 10.9 4.3e-05 24.2 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO01914.1 - 0.0014 18.9 0.4 2 8.8 0.1 3.7 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Motile_Sperm PF00635.26 EOO01915.1 - 9.1e-24 83.4 0.3 1.6e-23 82.6 0.2 1.5 1 1 0 1 1 1 1 MSP (Major sperm protein) domain FixG_C PF11614.8 EOO01915.1 - 0.017 15.4 0.2 0.1 12.8 0.1 2.0 1 1 1 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase ASH PF15780.5 EOO01915.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin UBX PF00789.20 EOO01916.1 - 2.4e-07 30.8 0.0 7.6e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 EOO01916.1 - 0.00088 19.1 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2_2 PF12756.7 EOO01916.1 - 0.0053 17.1 0.2 0.013 15.8 0.2 1.6 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) NOZZLE PF08744.10 EOO01916.1 - 0.023 14.2 1.1 0.034 13.6 1.1 1.2 1 0 0 1 1 1 0 Plant transcription factor NOZZLE zf-C2HE PF16278.5 EOO01916.1 - 0.64 10.5 0.1 0.64 10.5 0.1 3.0 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Emaravirus_P4 PF16505.5 EOO01916.1 - 3.7 6.5 7.9 6.3 5.7 7.4 1.5 1 1 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily GREB1 PF15782.5 EOO01916.1 - 7.7 3.5 9.7 7.8 3.5 9.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 EOO01916.1 - 7.8 5.0 16.2 9.1 4.8 16.2 1.0 1 0 0 1 1 1 0 Hamartin protein CDC45 PF02724.14 EOO01916.1 - 7.9 4.6 14.6 9.4 4.4 14.6 1.3 1 0 0 1 1 1 0 CDC45-like protein adh_short PF00106.25 EOO01917.1 - 7.3e-21 74.5 0.0 3.2e-16 59.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EOO01917.1 - 6.7e-14 52.0 0.0 1.5e-12 47.6 0.1 2.3 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO01917.1 - 0.0029 17.6 0.1 0.0048 16.8 0.1 1.3 1 0 0 1 1 1 1 KR domain UCR_14kD PF02271.16 EOO01918.1 - 5e-42 141.9 0.2 5.8e-42 141.7 0.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit adh_short_C2 PF13561.6 EOO01919.1 - 2.6e-48 164.6 0.7 5.3e-42 144.0 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO01919.1 - 5.5e-43 146.7 0.2 6.8e-43 146.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO01919.1 - 3.2e-13 50.0 0.1 4.6e-13 49.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO01919.1 - 4.5e-06 26.3 0.1 3.7e-05 23.3 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO01919.1 - 0.0072 15.8 0.1 0.096 12.1 0.1 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Ribosomal_L26 PF16906.5 EOO01919.1 - 0.13 12.8 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal AhpC-TSA PF00578.21 EOO01920.1 - 1.8e-25 89.3 0.0 2.4e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EOO01920.1 - 3e-14 52.9 0.0 4.2e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EOO01920.1 - 0.0096 16.0 0.0 0.043 13.9 0.0 1.7 1 1 1 2 2 2 1 AhpC/TSA antioxidant enzyme AbfS_sensor PF18225.1 EOO01920.1 - 0.085 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain CI-B14_5a PF07347.12 EOO01921.1 - 0.065 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) zf-CCHC PF00098.23 EOO01922.1 - 2.5e-30 103.2 31.0 3.2e-10 39.6 3.6 4.2 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 EOO01922.1 - 1.1e-06 28.2 18.6 0.043 13.6 1.1 4.0 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.6 EOO01922.1 - 1.7e-05 24.7 20.3 0.14 12.2 1.8 4.1 2 1 2 4 4 4 3 Zinc knuckle zf-CCHC_2 PF13696.6 EOO01922.1 - 0.0013 18.5 6.6 0.0054 16.5 1.7 4.4 4 1 0 4 4 4 2 Zinc knuckle zf-CCHC_5 PF14787.6 EOO01922.1 - 0.0038 16.9 14.7 2.6 7.8 0.1 4.1 3 1 1 4 4 4 3 GAG-polyprotein viral zinc-finger zf-C2H2_10 PF16588.5 EOO01922.1 - 0.23 11.2 0.4 0.23 11.2 0.4 4.2 4 0 0 4 4 4 0 C2H2 zinc-finger zf-CCHC_6 PF15288.6 EOO01922.1 - 2.3 8.1 27.1 0.2 11.5 1.8 3.9 3 1 1 4 4 4 0 Zinc knuckle PolC_DP2 PF03833.13 EOO01922.1 - 5 4.9 5.4 5.1 4.8 5.4 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 TRAF6_Z2 PF18048.1 EOO01922.1 - 5.9 7.1 11.5 50 4.1 1.3 4.2 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 Ribosomal_60s PF00428.19 EOO01923.1 - 3.1e-26 91.8 13.4 3.8e-26 91.5 13.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2967 PF11179.8 EOO01923.1 - 2.6 6.0 4.5 3 5.8 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) 4HBT_3 PF13622.6 EOO01924.1 - 2.8e-19 70.3 0.0 7.1e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Thioesterase-like superfamily Membr_traf_MHD PF10540.9 EOO01924.1 - 4.9e-17 62.5 2.4 4.1e-08 33.5 1.0 3.0 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EOO01924.1 - 1.8e-16 60.3 0.0 4.1e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 EOO01924.1 - 1.5e-09 37.0 0.2 2.7e-09 36.2 0.2 1.3 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) 4HBT PF03061.22 EOO01924.1 - 0.05 13.9 0.2 0.3 11.5 0.0 2.4 2 0 0 2 2 2 0 Thioesterase superfamily Rep_N PF08724.10 EOO01924.1 - 0.068 12.9 0.2 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 Rep protein catalytic domain like DUF4473 PF14747.6 EOO01924.1 - 0.54 10.9 4.5 1.8 9.2 0.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) AIM5 PF17050.5 EOO01924.1 - 1 10.2 3.3 0.82 10.5 0.0 2.6 3 0 0 3 3 3 0 Altered inheritance of mitochondria 5 DUF5102 PF17104.5 EOO01925.1 - 5.3e-115 384.4 0.7 5.3e-115 384.4 0.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5102) eIF2_C PF09173.11 EOO01926.1 - 1.8e-34 117.8 0.6 4.1e-34 116.7 0.6 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EOO01926.1 - 1.9e-22 79.8 0.9 2.5e-21 76.1 0.9 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EOO01926.1 - 1.3e-10 41.5 0.2 2.8e-10 40.5 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EOO01926.1 - 0.0033 17.5 0.0 0.0079 16.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EOO01926.1 - 0.0062 16.5 0.8 0.021 14.8 0.1 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 EOO01926.1 - 0.025 14.5 0.2 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase BAR_3 PF16746.5 EOO01927.1 - 3.5e-23 82.5 11.7 5.1e-23 82.0 11.7 1.1 1 0 0 1 1 1 1 BAR domain of APPL family EMP24_GP25L PF01105.24 EOO01927.1 - 0.059 13.3 3.8 0.4 10.6 2.6 2.3 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD tRNA-synt_2 PF00152.20 EOO01927.1 - 0.12 11.4 1.5 0.19 10.8 1.5 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Pkinase PF00069.25 EOO01928.1 - 1e-76 257.8 0.0 1.9e-76 256.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO01928.1 - 7.2e-39 133.6 0.0 1.1e-38 133.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EOO01928.1 - 7.4e-17 61.5 0.3 1.7e-16 60.3 0.0 1.8 2 0 0 2 2 1 1 FHA domain Kinase-like PF14531.6 EOO01928.1 - 1.3e-10 41.1 0.0 2e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 EOO01928.1 - 9.7e-09 35.4 0.0 2.9e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 EOO01928.1 - 2.9e-06 26.3 0.0 5.9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EOO01928.1 - 0.00028 20.3 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EOO01928.1 - 0.0045 16.6 0.1 1.6 8.3 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 EOO01928.1 - 0.0052 16.3 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 EOO01928.1 - 0.01 15.8 0.1 0.097 12.6 0.1 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF2961 PF11175.8 EOO01928.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) Pox_ser-thr_kin PF05445.11 EOO01928.1 - 0.15 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EOO01928.1 - 0.26 10.9 1.3 0.46 10.0 0.5 1.8 2 1 0 2 2 2 0 RIO1 family ADK PF00406.22 EOO01930.1 - 4.3e-45 153.5 0.0 7e-45 152.8 0.0 1.3 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EOO01930.1 - 1.2e-35 122.9 0.0 1.6e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EOO01930.1 - 9e-07 29.5 0.0 1.3e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EOO01930.1 - 0.00011 21.9 0.1 0.24 11.0 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 EOO01930.1 - 0.00051 20.2 0.1 0.0022 18.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain MRP_L53 PF10780.9 EOO01932.1 - 9.1e-22 77.0 0.8 1.3e-21 76.5 0.8 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Ecotin PF03974.13 EOO01932.1 - 0.039 14.0 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 Ecotin KorB_C PF06613.11 EOO01932.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain Pyrophosphatase PF00719.19 EOO01933.1 - 6.9e-58 195.0 0.1 8.9e-58 194.6 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase PfkB PF00294.24 EOO01934.1 - 1.5e-17 63.9 0.2 2.3e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Sec20 PF03908.13 EOO01935.1 - 2.2e-14 53.1 2.4 2.2e-14 53.1 0.5 1.9 2 0 0 2 2 2 1 Sec20 Senescence PF06911.12 EOO01935.1 - 0.042 14.2 0.2 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 Senescence-associated protein FapA PF03961.13 EOO01935.1 - 0.21 10.1 3.0 0.78 8.3 0.8 2.1 1 1 0 2 2 2 0 Flagellar Assembly Protein A DASH_Dam1 PF08653.10 EOO01935.1 - 3.4 7.5 6.7 7.4 6.5 0.4 2.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 SlyX PF04102.12 EOO01935.1 - 3.7 8.3 8.1 30 5.3 0.3 3.7 3 0 0 3 3 3 0 SlyX Indigoidine_A PF04227.12 EOO01936.1 - 8.1e-114 379.9 0.6 9.5e-114 379.7 0.6 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein PCI PF01399.27 EOO01937.1 - 9.7e-12 45.3 0.2 2.5e-11 44.0 0.2 1.8 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 EOO01937.1 - 1.5e-08 34.2 1.5 3.2e-08 33.1 1.5 1.6 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix K_channel_TID PF07941.11 EOO01937.1 - 9.3 6.8 11.8 25 5.4 11.8 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF202 PF02656.15 EOO01938.1 - 0.0064 16.9 2.1 1.4 9.4 0.1 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF202) DUF1218 PF06749.12 EOO01938.1 - 1.4 9.5 6.1 0.66 10.5 3.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1218) MARVEL PF01284.23 EOO01938.1 - 3.9 7.5 10.9 5.8 6.9 10.0 1.7 1 1 1 2 2 2 0 Membrane-associating domain WD40 PF00400.32 EOO01940.1 - 5.1e-08 33.4 0.0 0.89 10.5 0.0 5.1 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO01940.1 - 7.6e-06 26.1 0.0 0.09 13.1 0.0 4.5 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EOO01940.1 - 0.00055 19.8 0.0 0.0024 17.7 0.0 2.1 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat TAF1D PF15333.6 EOO01940.1 - 0.025 14.3 0.2 0.025 14.3 0.2 1.5 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D NmrA PF05368.13 EOO01942.1 - 6e-62 209.2 0.0 7.8e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO01942.1 - 3.8e-19 69.3 0.0 5.1e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EOO01942.1 - 6e-06 25.5 0.0 8.7e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4350 PF14258.6 EOO01942.1 - 0.013 15.9 0.3 5.1 7.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) Topo_Zn_Ribbon PF08272.11 EOO01942.1 - 0.13 11.9 0.0 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like DIOX_N PF14226.6 EOO01943.1 - 5.6e-26 91.6 0.0 8.5e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EOO01943.1 - 2.2e-22 79.4 0.0 4e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 EOO01944.1 - 4.1e-29 101.6 25.8 4.8e-29 101.4 24.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MWFE PF15879.5 EOO01944.1 - 0.11 12.6 2.8 9.4 6.5 0.0 3.7 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit DUF3262 PF11660.8 EOO01944.1 - 0.4 11.1 0.1 0.4 11.1 0.1 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3262) Glyco_hydro_88 PF07470.13 EOO01945.1 - 5.5e-86 288.8 1.3 6.2e-86 288.6 1.3 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MatE PF01554.18 EOO01948.1 - 9.8e-54 181.3 22.7 1.5e-28 99.4 9.5 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EOO01948.1 - 1.6e-08 34.7 5.9 1.6e-08 34.7 5.9 4.0 3 2 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain DSX_dimer PF08828.10 EOO01948.1 - 0.1 12.3 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Doublesex dimerisation domain MFS_1 PF07690.16 EOO01949.1 - 1.2e-22 80.4 16.0 1.2e-22 80.4 16.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO01949.1 - 2.3e-12 46.5 0.3 2.6e-12 46.4 0.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 EOO01949.1 - 3.3e-05 22.5 5.3 4.3e-05 22.1 5.3 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector TRI12 PF06609.13 EOO01949.1 - 0.0059 15.1 3.1 0.0078 14.7 3.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.19 EOO01949.1 - 0.025 13.4 1.1 0.038 12.8 1.1 1.2 1 0 0 1 1 1 0 LacY proton/sugar symporter MFS_1_like PF12832.7 EOO01949.1 - 0.049 12.5 1.2 0.065 12.1 0.1 1.7 1 1 1 2 2 2 0 MFS_1 like family DUF4131 PF13567.6 EOO01949.1 - 1.4 8.6 6.5 0.32 10.6 2.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Spc7 PF08317.11 EOO01950.1 - 0.0036 16.2 25.2 0.0036 16.2 25.2 5.5 2 1 4 6 6 6 4 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 EOO01950.1 - 0.015 15.5 9.0 0.015 15.5 9.0 8.2 2 2 6 8 8 8 0 TATA element modulatory factor 1 TATA binding Phage_holin_7_1 PF16081.5 EOO01950.1 - 0.28 11.4 11.5 1.4 9.1 1.4 3.3 2 1 1 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family MFS_1 PF07690.16 EOO01951.1 - 3.6e-33 114.9 22.9 4.5e-33 114.6 22.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO01951.1 - 2.2e-15 56.5 2.9 4.1e-15 55.6 2.9 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EOO01951.1 - 2.7e-05 22.8 4.2 3.8e-05 22.3 4.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EOO01951.1 - 0.024 12.9 0.1 0.058 11.7 0.1 1.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family NmrA PF05368.13 EOO01952.1 - 2.5e-24 86.2 0.0 3.1e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO01952.1 - 3.7e-12 46.5 0.0 5.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EOO01952.1 - 1.5e-10 41.4 0.2 3.3e-10 40.3 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EOO01952.1 - 3.1e-05 24.0 0.1 7.5e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 EOO01952.1 - 0.00012 21.6 0.1 0.00052 19.5 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EOO01952.1 - 0.0012 18.9 0.1 0.0026 17.9 0.0 1.6 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 EOO01952.1 - 0.029 13.5 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EOO01952.1 - 0.042 13.0 0.0 0.092 11.9 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.24 EOO01952.1 - 0.044 14.2 0.0 0.092 13.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EOO01952.1 - 0.097 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NRIP1_repr_3 PF15689.5 EOO01952.1 - 0.15 12.3 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 3 adh_short PF00106.25 EOO01953.1 - 3.4e-28 98.4 0.0 5.2e-27 94.6 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO01953.1 - 4.4e-20 72.2 0.0 1.1e-19 71.0 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EOO01953.1 - 8.4e-06 25.8 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EOO01953.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EOO01953.1 - 0.0016 18.0 0.0 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO01953.1 - 0.026 13.9 0.0 0.089 12.2 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 EOO01953.1 - 0.026 15.1 0.0 0.055 14.0 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 EOO01953.1 - 0.14 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain PAE PF03283.13 EOO01953.1 - 0.24 10.5 0.2 0.41 9.7 0.2 1.3 1 0 0 1 1 1 0 Pectinacetylesterase Arginase PF00491.21 EOO01954.1 - 8.2e-91 304.4 0.0 1e-90 304.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EOO01954.1 - 0.073 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain Sugar_tr PF00083.24 EOO01955.1 - 4.6e-70 236.7 24.1 5.2e-70 236.5 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO01955.1 - 2.2e-08 33.4 43.3 5.1e-08 32.2 35.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EOO01955.1 - 1.8e-05 23.5 13.4 0.0033 16.1 2.5 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EOO01955.1 - 0.0048 15.8 6.4 0.0048 15.8 6.4 2.6 3 0 0 3 3 3 2 MFS_1 like family Transp_cyt_pur PF02133.15 EOO01957.1 - 1.8e-25 89.6 33.6 2.7e-25 89.0 33.6 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Abhydrolase_4 PF08386.10 EOO01958.1 - 4.4e-20 71.7 0.0 8.2e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 EOO01958.1 - 7.8e-13 48.7 0.1 0.00012 21.8 0.0 3.1 3 0 0 3 3 3 3 alpha/beta hydrolase fold Peptidase_S10 PF00450.22 EOO01959.1 - 3.8e-08 33.1 0.0 4.4e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_3_C PF01915.22 EOO01960.1 - 2.6e-50 171.2 0.0 4.6e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EOO01960.1 - 3.3e-42 145.0 0.0 4.9e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EOO01960.1 - 4.7e-26 90.7 0.0 9.3e-26 89.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Abhydrolase_3 PF07859.13 EOO01962.1 - 7.7e-58 195.8 0.0 9.8e-58 195.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 EOO01962.1 - 3.3e-05 23.6 0.0 0.0029 17.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EOO01962.1 - 5.3e-05 22.8 0.0 0.00066 19.2 0.0 2.1 1 1 1 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 EOO01962.1 - 0.00039 19.4 0.0 0.00089 18.2 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 EOO01962.1 - 0.0057 15.4 0.0 0.014 14.1 0.0 1.6 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 EOO01962.1 - 0.018 14.3 0.0 0.033 13.5 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Nrap_D5 PF17406.2 EOO01963.1 - 1.8e-59 200.1 0.4 3e-59 199.4 0.4 1.4 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 EOO01963.1 - 2.6e-43 147.9 0.1 3.8e-43 147.3 0.1 1.2 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D6 PF17407.2 EOO01963.1 - 8.8e-39 132.8 0.0 1.7e-38 131.9 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap_D2 PF17403.2 EOO01963.1 - 0.078 12.7 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain DASH_Dam1 PF08653.10 EOO01964.1 - 2.5e-27 94.4 1.3 3.5e-27 94.0 1.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 BolA PF01722.18 EOO01965.1 - 3.8e-21 75.2 0.0 9.4e-21 73.9 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein ASF1_hist_chap PF04729.13 EOO01966.1 - 5.4e-72 240.8 0.0 6.9e-72 240.4 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Thi4 PF01946.17 EOO01967.1 - 3.3e-115 383.3 0.1 4.1e-115 382.9 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EOO01967.1 - 1.2e-06 28.4 0.7 2.7e-06 27.2 0.4 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EOO01967.1 - 1.6e-05 25.1 0.4 4.2e-05 23.7 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EOO01967.1 - 8e-05 21.8 0.5 0.00021 20.5 0.5 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EOO01967.1 - 8.4e-05 21.9 0.1 0.00014 21.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EOO01967.1 - 0.0003 20.0 1.9 0.003 16.7 0.9 2.4 2 1 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 EOO01967.1 - 0.0057 16.7 1.7 0.0085 16.1 0.1 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EOO01967.1 - 0.013 14.9 0.1 0.02 14.3 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EOO01967.1 - 0.014 14.6 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EOO01967.1 - 0.019 13.7 0.8 0.028 13.1 0.8 1.3 1 0 0 1 1 1 0 HI0933-like protein CoA_trans PF01144.23 EOO01968.1 - 3.2e-98 327.5 0.5 2.2e-60 203.7 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Mog1 PF04603.12 EOO01969.1 - 5.3e-38 130.5 0.0 6.3e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Glyco_hydro_5_C PF18564.1 EOO01970.1 - 1.4e-20 73.6 0.0 3.2e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 EOO01970.1 - 1.2e-11 44.6 2.7 2.7e-07 30.3 1.1 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 EOO01970.1 - 0.0066 15.8 0.4 1.7 7.9 0.0 2.2 2 0 0 2 2 2 2 Beta-galactosidase XFP_N PF09364.10 EOO01971.1 - 6.4e-170 564.8 0.0 8.4e-170 564.4 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 EOO01971.1 - 7.3e-82 273.3 0.0 1.4e-81 272.4 0.0 1.5 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 EOO01971.1 - 3.3e-80 268.3 0.0 4.9e-80 267.8 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain UCH PF00443.29 EOO01972.1 - 1.1e-35 123.4 0.0 4.8e-35 121.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 EOO01972.1 - 4e-10 39.5 0.4 4.9e-08 32.8 0.1 3.3 3 0 0 3 3 3 1 A repeated domain in UCH-protein UCH_1 PF13423.6 EOO01972.1 - 7.6e-06 25.7 0.5 0.022 14.4 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ig_C17orf99 PF17736.1 EOO01972.1 - 0.0028 17.6 0.0 0.0068 16.4 0.0 1.6 1 0 0 1 1 1 1 C17orf99 Ig domain Med9 PF07544.13 EOO01973.1 - 2.4e-19 69.2 0.0 3.1e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 PRP9_N PF16958.5 EOO01973.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus Phage_GP20 PF06810.11 EOO01973.1 - 0.13 12.1 0.3 0.17 11.7 0.3 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 Gpi1 PF05024.15 EOO01974.1 - 2.2e-76 256.1 9.6 4.1e-76 255.2 9.6 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) GPI-anchored PF10342.9 EOO01974.1 - 5.1e-07 30.4 0.4 1.3e-06 29.1 0.0 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family 7tm_1 PF00001.21 EOO01974.1 - 0.0025 17.2 3.6 0.0029 17.0 0.7 2.2 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DNA_pol3_delta PF06144.13 EOO01974.1 - 0.38 10.5 1.4 0.61 9.8 1.4 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit ATP-synt_E PF05680.12 EOO01974.1 - 1.3 9.4 3.3 3.5 8.0 3.3 1.7 1 0 0 1 1 1 0 ATP synthase E chain iPGM_N PF06415.13 EOO01975.1 - 2.7e-79 265.6 0.0 3.8e-79 265.1 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 EOO01975.1 - 7.7e-67 225.2 0.0 8.9e-67 225.0 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EOO01975.1 - 9e-05 22.0 0.0 0.001 18.6 0.0 2.3 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EOO01975.1 - 0.0004 20.1 0.0 0.00076 19.2 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase AP_endonuc_2 PF01261.24 EOO01975.1 - 0.0048 16.4 0.0 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DUF1877 PF08974.10 EOO01975.1 - 0.13 12.3 0.0 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1877) AMMECR1 PF01871.17 EOO01976.1 - 9.1e-46 155.5 0.0 1.4e-45 154.9 0.0 1.3 1 1 0 1 1 1 1 AMMECR1 DUF5342 PF17277.2 EOO01976.1 - 0.066 13.6 0.0 0.97 9.8 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5342) PP28 PF10252.9 EOO01977.1 - 3.5e-28 97.9 17.5 3.5e-28 97.9 17.5 3.3 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 GP38 PF05268.11 EOO01977.1 - 0.49 10.0 4.7 0.65 9.6 4.7 1.1 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 TMIE PF16038.5 EOO01977.1 - 2.1 8.2 4.7 7.9 6.4 4.7 1.9 1 0 0 1 1 1 0 TMIE protein Glyco_hydro_17 PF00332.18 EOO01978.1 - 2.1e-08 34.2 3.8 9e-08 32.1 0.5 2.2 1 1 0 2 2 2 2 Glycosyl hydrolases family 17 PhageMin_Tail PF10145.9 EOO01978.1 - 0.0054 16.6 0.5 0.0088 15.9 0.5 1.4 1 0 0 1 1 1 1 Phage-related minor tail protein DUF167 PF02594.16 EOO01979.1 - 6.6e-22 77.4 0.6 1.1e-21 76.7 0.6 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 ThiJ_like PF17124.5 EOO01980.1 - 1.6e-63 213.9 0.0 2e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 EOO01980.1 - 4.3e-12 46.1 0.0 4.8e-11 42.7 0.0 2.3 1 1 0 1 1 1 1 DJ-1/PfpI family Esterase_phd PF10503.9 EOO01981.1 - 0.037 13.5 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 Esterase PHB depolymerase TPR_2 PF07719.17 EOO01982.1 - 8.3e-36 119.2 45.5 0.0061 16.6 0.2 16.8 16 0 0 16 16 16 8 Tetratricopeptide repeat TPR_19 PF14559.6 EOO01982.1 - 1.9e-35 121.2 28.9 1.2e-06 28.9 1.5 12.0 11 1 1 12 12 11 7 Tetratricopeptide repeat TPR_16 PF13432.6 EOO01982.1 - 1.2e-32 112.2 34.1 7.1e-07 29.8 0.9 11.4 11 1 1 12 12 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 EOO01982.1 - 1.4e-29 100.7 39.3 0.0011 18.7 0.0 15.9 18 0 0 18 18 17 8 Tetratricopeptide repeat TPR_14 PF13428.6 EOO01982.1 - 3.2e-29 99.1 37.8 0.0059 17.3 0.1 15.8 12 5 5 17 17 15 8 Tetratricopeptide repeat TPR_17 PF13431.6 EOO01982.1 - 4.3e-23 80.0 8.9 0.5 10.9 0.0 14.7 16 0 0 16 16 15 4 Tetratricopeptide repeat TPR_8 PF13181.6 EOO01982.1 - 3.6e-22 76.7 29.2 0.069 13.4 0.0 14.0 15 0 0 15 15 12 5 Tetratricopeptide repeat TPR_12 PF13424.6 EOO01982.1 - 2.2e-20 72.7 41.7 0.0059 16.9 0.1 14.0 9 4 5 15 15 13 7 Tetratricopeptide repeat TPR_11 PF13414.6 EOO01982.1 - 5.8e-20 70.7 21.9 0.0013 18.4 0.0 10.7 12 0 0 12 12 11 6 TPR repeat TPR_7 PF13176.6 EOO01982.1 - 1.8e-14 52.6 28.1 0.032 14.3 0.1 13.5 14 1 1 15 15 13 3 Tetratricopeptide repeat TPR_9 PF13371.6 EOO01982.1 - 6.1e-11 42.3 14.0 0.085 13.0 0.7 8.4 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 EOO01982.1 - 2.8e-07 30.7 29.0 0.71 10.6 0.1 13.2 16 0 0 16 16 11 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EOO01982.1 - 1.9e-06 28.0 24.9 1.9 8.8 0.1 9.5 10 2 2 12 12 11 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_22 PF18833.1 EOO01982.1 - 3.4e-06 27.1 0.0 8.3e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 EOO01982.1 - 0.00073 19.3 20.9 0.99 9.4 0.1 9.6 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_20 PF14561.6 EOO01982.1 - 0.00079 19.7 14.1 1.7 9.0 0.3 6.8 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 EOO01982.1 - 0.0012 19.2 20.0 1.9 9.4 0.3 9.3 10 0 0 10 10 8 1 Tetratricopeptide repeat DUF2225 PF09986.9 EOO01982.1 - 0.0014 18.4 3.3 0.98 9.1 0.3 3.7 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) Coatomer_WDAD PF04053.14 EOO01982.1 - 0.01 14.9 0.1 0.036 13.1 0.0 1.8 2 0 0 2 2 2 0 Coatomer WD associated region ChAPs PF09295.10 EOO01982.1 - 0.017 14.2 1.0 9.4 5.1 0.0 3.5 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_3 PF07720.12 EOO01982.1 - 0.035 14.1 9.7 25 5.0 0.6 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat RPN7 PF10602.9 EOO01982.1 - 0.053 13.2 0.3 6.4 6.4 0.1 4.0 4 0 0 4 4 4 0 26S proteasome subunit RPN7 FAT PF02259.23 EOO01982.1 - 0.15 11.2 4.8 21 4.2 0.0 4.7 4 1 1 5 5 5 0 FAT domain Fis1_TPR_C PF14853.6 EOO01982.1 - 0.17 11.9 5.9 78 3.5 0.0 6.2 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Ku_N PF03731.15 EOO01982.1 - 0.2 11.4 0.1 0.44 10.2 0.1 1.6 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain HemY_N PF07219.13 EOO01982.1 - 0.84 9.9 13.6 23 5.2 0.0 6.4 6 1 1 7 7 7 0 HemY protein N-terminus BTAD PF03704.17 EOO01982.1 - 1.3 9.4 18.1 0.46 10.9 0.1 6.0 7 0 0 7 7 7 0 Bacterial transcriptional activator domain IBR PF01485.21 EOO01983.1 - 2e-22 79.2 48.0 1.7e-12 47.3 6.1 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EOO01983.1 - 9.4e-06 25.4 43.3 0.00071 19.4 7.0 4.6 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EOO01983.1 - 0.0011 19.2 44.2 0.0052 17.1 7.8 4.1 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 EOO01983.1 - 0.017 14.9 43.0 0.087 12.7 5.7 5.0 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.8 EOO01983.1 - 0.026 15.0 0.0 0.058 13.9 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-RING_UBOX PF13445.6 EOO01983.1 - 0.036 14.1 34.6 0.14 12.2 5.4 3.9 3 1 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EOO01983.1 - 0.051 13.7 1.2 0.051 13.7 1.2 4.5 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EOO01983.1 - 0.79 10.1 35.1 1.1 9.5 4.0 3.7 3 0 0 3 3 3 0 RING-H2 zinc finger domain XPG_I PF00867.18 EOO01984.1 - 1.3e-23 83.1 0.2 3e-23 82.0 0.0 1.7 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EOO01984.1 - 9.9e-19 67.7 0.0 2.1e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 EOO01984.1 - 7.8e-05 22.3 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 EOO01984.1 - 0.17 12.5 0.0 0.51 11.0 0.0 1.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold ATP-synt_C PF00137.21 EOO01985.1 - 6.2e-11 42.5 12.5 1.2e-10 41.6 12.5 1.5 1 0 0 1 1 1 1 ATP synthase subunit C Ribo_biogen_C PF04034.13 EOO01986.1 - 1.6e-50 170.1 0.1 2.2e-50 169.6 0.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EOO01986.1 - 7e-12 45.0 1.2 7e-12 45.0 1.2 1.6 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI BUD22 PF09073.10 EOO01986.1 - 0.38 10.0 25.5 0.54 9.5 25.5 1.2 1 0 0 1 1 1 0 BUD22 TBCC PF07986.12 EOO01987.1 - 2.2e-30 104.8 0.0 3.8e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 EOO01987.1 - 2.6e-09 37.5 0.3 4.5e-09 36.8 0.3 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain RTX PF02382.15 EOO01987.1 - 0.062 13.0 0.1 0.094 12.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein DUF5082 PF16888.5 EOO01987.1 - 0.12 12.6 0.2 0.34 11.2 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) SprT-like PF10263.9 EOO01988.1 - 3.5e-39 133.2 2.3 6.3e-39 132.3 2.3 1.4 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 EOO01988.1 - 2.6e-09 36.8 3.6 4.8e-09 36.0 3.6 1.5 1 0 0 1 1 1 1 SprT-like zinc ribbon domain HMG_box PF00505.19 EOO01988.1 - 0.018 15.4 2.2 0.021 15.2 0.2 2.1 2 0 0 2 2 2 0 HMG (high mobility group) box Lyase_1 PF00206.20 EOO01988.1 - 0.07 12.5 2.0 0.044 13.2 0.3 1.5 2 0 0 2 2 2 0 Lyase DUF4872 PF16169.5 EOO01988.1 - 0.087 12.6 0.2 0.78 9.5 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4872) DUF155 PF02582.14 EOO01989.1 - 1.2e-50 172.0 0.0 1.8e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_1 PF00190.22 EOO01989.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 EOO01989.1 - 0.14 11.8 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Redoxin PF08534.10 EOO01990.1 - 1.6e-27 96.0 0.0 1.9e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin RMI1_N PF08585.12 EOO01991.1 - 2.2e-61 207.4 0.0 2.7e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 RecQ mediated genome instability protein Tim17 PF02466.19 EOO01992.1 - 3.4e-08 33.8 9.4 5.5e-08 33.2 9.4 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DNA_primase_S PF01896.19 EOO01993.1 - 6.8e-65 218.4 0.7 9.3e-65 218.0 0.7 1.2 1 0 0 1 1 1 1 DNA primase small subunit Clr5 PF14420.6 EOO01994.1 - 1e-18 67.3 3.0 2.6e-18 66.0 3.0 1.8 1 0 0 1 1 1 1 Clr5 domain MutS_V PF00488.21 EOO01996.1 - 7.3e-84 280.5 0.1 1.3e-83 279.7 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EOO01996.1 - 3.5e-38 131.7 1.1 1.2e-37 130.0 1.1 1.9 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 EOO01996.1 - 1e-20 74.4 1.6 1.9e-20 73.5 0.0 2.4 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.20 EOO01996.1 - 4.5e-20 72.0 0.0 2.9e-19 69.4 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 EOO01996.1 - 1.4e-05 25.4 4.6 0.0084 16.4 0.5 4.0 3 1 1 4 4 4 2 MutS family domain IV AAA_27 PF13514.6 EOO01996.1 - 0.062 12.9 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Phage_Gp111 PF07410.11 EOO01996.1 - 0.069 13.6 0.1 5 7.6 0.0 3.2 3 0 0 3 3 3 0 Streptococcus thermophilus bacteriophage Gp111 protein AAA_22 PF13401.6 EOO01996.1 - 1.1 9.5 3.0 7.8 6.8 0.0 3.4 4 1 0 4 4 4 0 AAA domain eIF2A PF08662.11 EOO01998.1 - 6.4e-78 261.1 0.0 1.9e-77 259.5 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EOO01998.1 - 0.0026 18.5 0.5 12 7.0 0.1 4.7 4 1 1 5 5 5 1 WD domain, G-beta repeat Aminotran_1_2 PF00155.21 EOO01999.1 - 6.3e-36 124.3 0.0 7.6e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EOO01999.1 - 0.089 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF676 PF05057.14 EOO02000.1 - 0.00023 20.8 0.1 0.0016 18.0 0.1 2.1 1 1 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EOO02000.1 - 0.016 15.8 0.0 0.024 15.3 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 EOO02000.1 - 0.027 14.2 0.1 0.064 13.0 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 EOO02000.1 - 0.13 11.5 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Glucan_synthase PF02364.15 EOO02001.1 - 0 1371.3 0.0 0 1370.7 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EOO02001.1 - 8.7e-44 149.0 0.7 2.9e-43 147.3 0.7 2.0 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 MAM33 PF02330.16 EOO02002.1 - 1.5e-76 257.0 0.0 2.1e-76 256.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein HIT PF01230.23 EOO02003.1 - 8.4e-24 84.2 0.1 1.2e-23 83.7 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EOO02003.1 - 1.5e-13 51.3 0.0 2.2e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EOO02003.1 - 8.1e-05 22.5 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 His_Phos_2 PF00328.22 EOO02004.1 - 5.7e-39 134.5 0.0 1.9e-18 67.0 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DNA_pol_A_exo1 PF01612.20 EOO02005.1 - 7.2e-43 146.3 0.2 1.1e-42 145.7 0.2 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 EOO02005.1 - 2.7e-29 101.7 1.1 1.6e-28 99.2 0.3 2.7 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 EOO02005.1 - 6.4e-14 51.7 0.2 2.1e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 HRDC domain YqfQ PF14181.6 EOO02005.1 - 0.71 10.1 3.9 1.9 8.6 3.9 1.7 1 0 0 1 1 1 0 YqfQ-like protein Suf PF05843.14 EOO02006.1 - 6.7e-36 124.8 1.3 3.8e-33 115.7 0.0 3.5 3 2 0 3 3 3 2 Suppressor of forked protein (Suf) Vps51 PF08700.11 EOO02007.1 - 1.2e-20 73.4 0.7 1.9e-20 72.7 0.7 1.2 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 EOO02007.1 - 0.011 14.5 0.2 0.014 14.1 0.2 1.1 1 0 0 1 1 1 0 Dor1-like family NIF3 PF01784.18 EOO02008.1 - 2.7e-62 210.6 0.0 3.7e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) VHS PF00790.19 EOO02009.1 - 5.9e-46 155.8 0.0 3.6e-45 153.3 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 EOO02009.1 - 3.4e-21 75.3 2.2 6e-21 74.5 0.2 2.4 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 EOO02009.1 - 1.9e-08 33.8 1.7 8.1e-08 31.8 0.1 2.8 3 0 0 3 3 3 1 GGA N-GAT domain DUF5344 PF17279.2 EOO02009.1 - 0.048 14.2 0.1 0.18 12.4 0.1 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5344) GTP_EFTU PF00009.27 EOO02011.1 - 4.8e-32 111.1 7.6 1.7e-31 109.3 3.4 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EOO02011.1 - 3.1e-28 98.0 0.3 1.2e-27 96.0 0.3 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EOO02011.1 - 4.2e-09 36.5 0.0 1.1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EOO02011.1 - 9.5e-07 28.9 1.2 5.3e-06 26.4 0.1 2.3 1 1 1 2 2 2 1 RsgA GTPase Arf PF00025.21 EOO02011.1 - 5.5e-05 22.7 0.0 8.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU_D2 PF03144.25 EOO02011.1 - 7.4e-05 23.1 4.2 0.15 12.5 1.7 3.2 2 1 0 2 2 2 2 Elongation factor Tu domain 2 FeoB_N PF02421.18 EOO02011.1 - 0.00045 19.8 0.2 0.0016 18.0 0.2 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU_D4 PF14578.6 EOO02011.1 - 0.0014 18.4 0.9 0.013 15.4 0.0 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Roc PF08477.13 EOO02011.1 - 0.0098 16.1 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EOO02011.1 - 0.023 14.1 0.2 0.08 12.4 0.2 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 EOO02011.1 - 0.046 13.8 0.4 2.6 8.1 0.1 3.0 2 1 1 3 3 3 0 Dynamin family Ribosomal_60s PF00428.19 EOO02011.1 - 0.087 13.4 6.4 0.3 11.7 6.4 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pkinase PF00069.25 EOO02012.1 - 6.7e-59 199.4 0.0 9.6e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO02012.1 - 1.8e-43 148.7 0.0 2.7e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EOO02012.1 - 1.5e-08 34.3 0.0 1.5e-06 27.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EOO02012.1 - 0.0023 17.3 0.0 0.0062 15.9 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EOO02012.1 - 0.013 14.3 1.0 0.019 13.8 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 EOO02012.1 - 0.03 14.2 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family DNA_methylase PF00145.17 EOO02013.1 - 6.1e-32 111.3 0.0 9.4e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 EOO02013.1 - 0.00017 21.5 0.1 0.54 10.1 0.1 2.4 2 0 0 2 2 2 2 BAH domain Asp PF00026.23 EOO02014.1 - 4.4e-111 371.3 0.5 5.2e-111 371.0 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EOO02014.1 - 2.9e-16 60.2 2.2 5.8e-14 52.7 1.9 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EOO02014.1 - 0.00012 22.7 0.0 2.8 8.6 0.0 3.9 2 2 1 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EOO02014.1 - 0.0015 19.1 0.0 4.6 7.9 0.0 2.9 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EOO02014.1 - 0.0035 17.1 0.0 0.074 12.8 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gp45-slide_C PF09116.10 EOO02014.1 - 0.14 12.2 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal CP2 PF04516.15 EOO02015.1 - 9.3e-83 277.0 0.0 1.2e-82 276.7 0.0 1.1 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.14 EOO02015.1 - 0.016 14.0 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Tektin family TMF_DNA_bd PF12329.8 EOO02015.1 - 0.058 13.4 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding AKNA PF12443.8 EOO02015.1 - 0.085 13.5 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor CorA PF01544.18 EOO02016.1 - 1.7e-09 37.5 0.0 3.1e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Piwi PF02171.17 EOO02018.1 - 9.6e-74 248.3 0.2 1.4e-73 247.8 0.2 1.1 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EOO02018.1 - 4.6e-22 79.1 0.0 1.2e-21 77.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 EOO02018.1 - 1.7e-14 53.8 0.1 6.6e-14 52.0 0.1 2.1 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoL1 PF08699.10 EOO02018.1 - 8.3e-12 44.6 0.0 2.4e-11 43.1 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 EOO02018.1 - 3.2e-09 36.7 0.2 6e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 EOO02018.1 - 9e-09 35.5 0.0 3.7e-08 33.5 0.0 2.1 1 0 0 1 1 1 1 Mid domain of argonaute GPP34 PF05719.11 EOO02019.1 - 3.4e-69 233.0 0.2 4.2e-69 232.7 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Ras PF00071.22 EOO02020.1 - 3e-39 134.2 0.0 2.4e-25 89.0 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EOO02020.1 - 1.4e-11 44.7 0.1 2.8e-11 43.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EOO02020.1 - 0.0022 17.5 0.0 0.0089 15.5 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EOO02020.1 - 0.0039 17.2 0.0 0.0057 16.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase PRK PF00485.18 EOO02020.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GTP_EFTU PF00009.27 EOO02020.1 - 0.22 11.1 0.0 1.9 8.0 0.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MFS_1 PF07690.16 EOO02021.1 - 7e-16 58.1 38.2 7.1e-15 54.8 37.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily SURF6 PF04935.12 EOO02022.1 - 1.9e-51 174.7 35.8 1.9e-51 174.7 35.8 4.0 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 EOO02022.1 - 1.7e-06 28.5 4.0 1.7e-06 28.5 4.0 7.7 6 2 0 6 6 6 1 60S ribosome biogenesis protein Rrp14 Sortilin-Vps10 PF15902.5 EOO02023.1 - 0.0038 16.1 0.2 1.1 8.0 0.0 3.0 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, BNR_2 PF13088.6 EOO02023.1 - 0.0055 16.1 0.0 0.016 14.5 0.0 1.8 2 0 0 2 2 2 1 BNR repeat-like domain PUF PF00806.19 EOO02024.1 - 3.2e-13 48.5 0.0 0.029 14.1 0.0 6.0 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat Pyridoxal_deC PF00282.19 EOO02024.1 - 5.2e-12 45.2 0.0 7.9e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain MFS_1 PF07690.16 EOO02025.1 - 4.7e-36 124.5 36.0 4.7e-36 124.5 36.0 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily CRAL_TRIO PF00650.20 EOO02027.1 - 5.3e-43 146.5 0.1 1e-42 145.6 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EOO02027.1 - 1.1e-14 54.4 0.8 4.6e-14 52.3 0.1 2.3 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EOO02027.1 - 4.1e-07 30.2 0.0 6.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DNA_pol_A_exoN PF18305.1 EOO02027.1 - 0.091 13.1 0.1 0.28 11.5 0.1 1.8 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain Amidase PF01425.21 EOO02028.1 - 1.4e-90 304.5 0.0 1.7e-90 304.1 0.0 1.0 1 0 0 1 1 1 1 Amidase Cu2_monoox_C PF03712.15 EOO02029.1 - 1.2e-24 86.6 0.0 2.1e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 EOO02029.1 - 2.4e-24 86.0 0.1 4.7e-24 85.1 0.1 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 EOO02029.1 - 3e-16 59.7 0.1 8e-16 58.4 0.1 1.8 1 1 1 2 2 2 1 DOMON domain CDH-cyt PF16010.5 EOO02029.1 - 0.0013 18.5 0.8 0.0071 16.0 0.0 2.3 2 1 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase TRI12 PF06609.13 EOO02031.1 - 1.4e-22 79.9 19.8 2e-22 79.4 19.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EOO02031.1 - 3.7e-18 65.6 47.9 1.1e-15 57.5 45.6 3.3 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF4410 PF14366.6 EOO02031.1 - 0.65 9.9 2.4 4 7.3 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) NAD_binding_10 PF13460.6 EOO02032.1 - 7.1e-16 58.6 0.0 1.2e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EOO02032.1 - 6.1e-07 29.2 0.0 7.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 EOO02032.1 - 0.15 12.1 0.0 0.38 10.9 0.0 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus UQ_con PF00179.26 EOO02033.1 - 1.1e-30 106.1 0.0 1.5e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EOO02033.1 - 0.022 14.4 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 EOO02033.1 - 0.047 14.0 0.0 0.069 13.4 0.0 1.2 1 0 0 1 1 1 0 RWD domain Nop14 PF04147.12 EOO02034.1 - 2.1e-295 982.5 24.4 2.9e-295 982.0 24.4 1.2 1 0 0 1 1 1 1 Nop14-like family Sel1 PF08238.12 EOO02035.1 - 4.8e-11 43.0 7.1 0.0036 17.9 0.0 3.9 3 1 0 3 3 3 3 Sel1 repeat Peptidase_M22 PF00814.25 EOO02036.1 - 8.7e-44 150.2 0.0 7.1e-40 137.4 0.0 3.8 1 1 0 1 1 1 1 Glycoprotease family YycC PF14174.6 EOO02036.1 - 0.082 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 YycC-like protein DUF359 PF04019.12 EOO02036.1 - 0.17 11.5 0.0 8.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF359) COesterase PF00135.28 EOO02037.1 - 9.1e-85 285.5 0.0 3.4e-75 253.9 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EOO02037.1 - 3.6e-10 40.0 0.1 9.5e-10 38.7 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EOO02037.1 - 0.0026 18.4 4.5 0.011 16.4 4.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1168 PF06658.12 EOO02037.1 - 0.56 10.0 1.2 0.96 9.3 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Glyco_transf_34 PF05637.12 EOO02038.1 - 1.9e-65 221.0 0.4 2.5e-65 220.6 0.4 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Uso1_p115_head PF04869.14 EOO02038.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region RhoGAP PF00620.27 EOO02039.1 - 2.6e-37 128.0 0.2 8.1e-37 126.4 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 EOO02039.1 - 4.6e-06 26.8 9.8 8.5e-06 25.9 8.1 2.2 2 0 0 2 2 2 1 LIM domain zf-dskA_traR PF01258.17 EOO02039.1 - 2.7 8.0 5.7 1.4 9.0 1.3 2.7 2 1 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger DZR PF12773.7 EOO02039.1 - 6.1 7.0 10.2 3.4e+02 1.4 10.2 2.4 1 1 0 1 1 1 0 Double zinc ribbon 2-oxoacid_dh PF00198.23 EOO02040.1 - 6.5e-75 251.6 0.0 9.4e-75 251.0 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EOO02040.1 - 2e-16 59.6 0.0 7e-16 57.8 0.0 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 EOO02040.1 - 4.7e-13 49.2 0.3 4.7e-13 49.2 0.3 2.0 2 0 0 2 2 2 1 e3 binding domain SspB PF04386.13 EOO02040.1 - 0.17 11.7 0.6 0.39 10.6 0.6 1.5 1 0 0 1 1 1 0 Stringent starvation protein B AAA PF00004.29 EOO02041.1 - 7.9e-50 168.7 0.0 7.9e-44 149.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EOO02041.1 - 3.2e-05 24.4 0.2 0.0094 16.3 0.0 2.8 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EOO02041.1 - 7.3e-05 22.6 0.0 0.00026 20.8 0.0 2.0 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 EOO02041.1 - 0.00038 19.6 0.0 0.00064 18.9 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EOO02041.1 - 0.001 18.7 0.1 0.0093 15.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 EOO02041.1 - 0.0012 19.0 0.0 0.0038 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EOO02041.1 - 0.0028 17.4 0.0 0.0071 16.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EOO02041.1 - 0.0033 17.7 0.0 0.017 15.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 EOO02041.1 - 0.0039 17.6 0.0 0.016 15.6 0.0 2.1 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 EOO02041.1 - 0.0054 16.0 0.0 0.0093 15.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EOO02041.1 - 0.0079 15.6 0.3 0.025 14.0 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EOO02041.1 - 0.0088 16.0 0.0 0.05 13.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase PF06745.13 EOO02041.1 - 0.012 15.0 0.1 0.039 13.3 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 EOO02041.1 - 0.021 14.4 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EOO02041.1 - 0.039 13.4 0.0 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 EOO02041.1 - 0.04 14.5 0.0 0.08 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EOO02041.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EOO02041.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EOO02041.1 - 0.051 12.7 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EOO02041.1 - 0.066 12.9 0.0 0.72 9.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 EOO02041.1 - 0.076 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EOO02041.1 - 0.099 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EOO02041.1 - 0.11 12.4 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Vps4_C PF09336.10 EOO02041.1 - 0.12 12.4 0.2 1.7 8.7 0.0 2.7 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 EOO02041.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.17 EOO02041.1 - 0.2 10.4 0.0 0.36 9.6 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase Trehalase PF01204.18 EOO02042.1 - 3.1e-117 392.5 5.7 2.1e-116 389.8 5.7 1.9 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 EOO02042.1 - 0.00012 21.1 1.0 0.00041 19.4 0.1 1.9 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Clathrin-link PF09268.10 EOO02042.1 - 0.13 11.6 0.7 0.77 9.2 0.1 2.2 2 0 0 2 2 2 0 Clathrin, heavy-chain linker EF1_GNE PF00736.19 EOO02044.1 - 5e-33 113.2 1.7 9.9e-33 112.2 1.7 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EOO02044.1 - 1.4e-14 54.2 7.6 1.4e-14 54.2 7.6 2.4 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 EOO02044.1 - 0.0013 18.9 0.5 0.0046 17.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF211 PF02680.14 EOO02044.1 - 0.052 13.7 0.3 0.1 12.8 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Glyco_hydro_16 PF00722.21 EOO02045.1 - 4.7e-08 32.7 0.0 3e-07 30.1 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Pkinase PF00069.25 EOO02046.1 - 1.7e-33 116.1 0.0 4e-19 69.0 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EOO02046.1 - 1.2e-13 51.0 0.0 0.00013 21.4 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 EOO02046.1 - 0.0093 15.9 0.0 0.054 13.4 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EOO02046.1 - 0.011 15.0 0.0 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Ribosomal_L10 PF00466.20 EOO02047.1 - 9.7e-23 80.2 0.3 2.4e-22 78.9 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EOO02047.1 - 1.3e-22 79.5 0.0 2.3e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EOO02047.1 - 2.2e-18 66.6 5.8 4.4e-18 65.7 4.0 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein WRNPLPNID PF15017.6 EOO02047.1 - 0.037 14.9 1.2 0.067 14.1 1.2 1.4 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box CPT_N PF16484.5 EOO02047.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus tRNA-synt_2d PF01409.20 EOO02049.1 - 7.9e-86 287.5 0.0 1.1e-85 287.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EOO02049.1 - 4.3e-18 65.3 0.9 1e-17 64.1 0.9 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EOO02049.1 - 8.2e-07 28.7 0.0 0.0049 16.3 0.0 3.0 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 EOO02049.1 - 5.4e-05 22.4 0.1 0.0022 17.1 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 EOO02049.1 - 0.0016 18.3 0.8 0.0045 16.9 0.8 1.8 1 1 0 1 1 1 1 PheRS DNA binding domain 2 Oxidoreduct_C PF16490.5 EOO02049.1 - 0.057 13.1 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain tRNA-synt_1e PF01406.19 EOO02050.1 - 1.4e-117 392.3 0.0 4e-117 390.9 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EOO02050.1 - 1.2e-05 24.3 0.4 0.092 11.5 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 EOO02050.1 - 0.19 10.6 0.0 0.19 10.6 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain DUF3776 PF12618.8 EOO02050.1 - 0.32 11.6 5.7 1.1 9.9 5.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3776) 40S_SA_C PF16122.5 EOO02050.1 - 0.8 11.1 7.2 2.3 9.6 7.2 1.8 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus Ribosomal_L29 PF00831.23 EOO02051.1 - 1.5e-16 60.0 1.6 1.5e-16 60.0 1.6 2.0 2 1 0 2 2 2 1 Ribosomal L29 protein Oxidored_FMN PF00724.20 EOO02052.1 - 1.9e-72 244.4 0.0 8.8e-68 229.1 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Sec63 PF02889.16 EOO02053.1 - 3.3e-167 554.1 0.0 2e-93 312.3 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EOO02053.1 - 3.2e-49 167.1 0.1 4.2e-28 98.3 0.1 3.7 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EOO02053.1 - 4.4e-35 120.2 1.8 1.3e-34 118.7 1.8 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EOO02053.1 - 8.8e-24 84.4 0.0 2e-13 50.7 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EOO02053.1 - 1.1e-10 41.8 0.0 1e-07 32.3 0.0 3.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EOO02053.1 - 5.5e-06 26.7 0.1 0.019 15.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 EOO02053.1 - 0.0015 17.7 0.0 1 8.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 EOO02053.1 - 0.015 14.7 0.0 0.62 9.5 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein TFIIE_alpha PF02002.17 EOO02053.1 - 0.095 12.6 1.4 3 7.8 0.0 3.3 3 0 0 3 3 3 0 TFIIE alpha subunit Peptidase_M28 PF04389.17 EOO02054.1 - 1e-33 116.7 0.0 1.6e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 But2 PF09792.9 EOO02055.1 - 8.9e-09 35.9 0.4 1.2e-08 35.5 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain IU_nuc_hydro PF01156.19 EOO02056.1 - 7.8e-58 196.4 0.0 1.5e-57 195.5 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DnaJ_C PF01556.18 EOO02057.1 - 1.3e-38 132.4 0.0 1.7e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EOO02057.1 - 6.5e-26 90.2 2.9 1.1e-25 89.5 2.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EOO02057.1 - 5.8e-17 61.8 17.8 1e-16 61.0 17.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EOO02057.1 - 0.0014 18.5 17.8 0.054 13.5 3.3 2.7 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EOO02057.1 - 0.038 14.0 9.4 0.79 9.8 2.6 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Peptidase_C74 PF12387.8 EOO02057.1 - 0.29 10.6 0.6 0.5 9.8 0.6 1.3 1 0 0 1 1 1 0 Pestivirus NS2 peptidase zinc-ribbons_6 PF07191.12 EOO02057.1 - 0.39 10.7 8.1 4.7 7.3 2.4 2.4 1 1 1 2 2 2 0 zinc-ribbons DUF2614 PF11023.8 EOO02057.1 - 0.9 9.7 5.6 2.2 8.4 1.0 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain zinc_ribbon_9 PF14369.6 EOO02057.1 - 3.6 7.9 7.9 22 5.4 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon DZR PF12773.7 EOO02057.1 - 5 7.2 11.0 6.9e+02 0.4 11.0 2.3 1 1 0 1 1 1 0 Double zinc ribbon MutS_V PF00488.21 EOO02058.1 - 3.6e-69 232.6 0.1 8.6e-69 231.3 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EOO02058.1 - 1.7e-48 165.4 4.5 2.7e-48 164.7 4.5 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EOO02058.1 - 1.5e-18 67.1 0.0 4.5e-18 65.5 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EOO02058.1 - 1.6e-09 38.1 0.0 5.5e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.6 EOO02058.1 - 0.076 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EOO02058.1 - 0.11 13.0 0.1 0.33 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Acetyltransf_3 PF13302.7 EOO02059.1 - 4.2e-27 95.5 0.0 5.2e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EOO02059.1 - 2.4e-05 24.5 0.0 3.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EOO02059.1 - 3.4e-05 24.0 0.0 4.3e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EOO02059.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sld5 PF05916.11 EOO02060.1 - 1.5e-13 51.1 0.0 2.2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Cgr1 PF03879.14 EOO02061.1 - 5.2e-32 110.4 32.3 5.7e-32 110.3 32.3 1.0 1 0 0 1 1 1 1 Cgr1 family PRP1_N PF06424.12 EOO02061.1 - 0.35 11.2 11.3 0.44 10.9 11.3 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Prismane PF03063.20 EOO02061.1 - 0.71 8.5 4.7 0.76 8.4 4.7 1.0 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family RRT14 PF17075.5 EOO02061.1 - 0.82 9.8 17.1 1 9.5 17.1 1.1 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 DRY_EERY PF09750.9 EOO02061.1 - 3.2 8.0 13.6 4.1 7.7 13.6 1.1 1 0 0 1 1 1 0 Alternative splicing regulator Silic_transp PF03842.13 EOO02061.1 - 6.5 4.9 6.2 7.2 4.8 6.2 1.0 1 0 0 1 1 1 0 Silicon transporter COPIIcoated_ERV PF07970.12 EOO02062.1 - 1.2e-88 296.7 0.0 3e-88 295.4 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EOO02062.1 - 3.2e-08 33.8 0.4 9.3e-08 32.3 0.1 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PhoD PF09423.10 EOO02063.1 - 7e-06 25.3 0.5 0.00052 19.1 0.0 2.4 3 0 0 3 3 3 2 PhoD-like phosphatase zf-HC5HC2H_2 PF13832.6 EOO02065.1 - 9.7e-20 70.8 1.4 9.7e-20 70.8 1.4 4.4 5 0 0 5 5 5 2 PHD-zinc-finger like domain BAH PF01426.18 EOO02065.1 - 9.6e-19 67.4 0.1 2e-18 66.4 0.1 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 EOO02065.1 - 3.6e-16 59.2 2.0 3.6e-16 59.2 2.0 4.9 4 1 1 5 5 5 1 PHD-like zinc-binding domain PHD PF00628.29 EOO02065.1 - 1.1e-11 44.4 56.2 8.3e-07 28.8 8.7 6.0 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.6 EOO02065.1 - 4.2e-08 32.6 3.9 4.2e-08 32.6 3.9 5.2 6 0 0 6 6 6 2 PHD-finger C1_1 PF00130.22 EOO02065.1 - 0.0057 16.5 2.3 0.0057 16.5 2.3 6.0 5 1 1 6 6 6 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EOO02065.1 - 0.027 14.8 0.4 0.027 14.8 0.4 6.4 7 0 0 7 7 7 0 C1 domain GATA PF00320.27 EOO02065.1 - 0.04 13.5 0.4 0.04 13.5 0.4 3.7 4 0 0 4 4 3 0 GATA zinc finger TrkA_C PF02080.21 EOO02065.1 - 0.21 11.4 0.0 0.53 10.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-C domain Prok-RING_1 PF14446.6 EOO02065.1 - 1.4 8.9 36.3 0.31 11.0 1.7 4.4 4 0 0 4 4 3 0 Prokaryotic RING finger family 1 RICTOR_phospho PF14665.6 EOO02065.1 - 2 8.8 4.6 0.81 10.0 0.4 2.3 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site Apt1 PF10351.9 EOO02065.1 - 4 6.2 7.3 12 4.6 7.3 1.8 1 0 0 1 1 1 0 Golgi-body localisation protein domain EMP24_GP25L PF01105.24 EOO02066.1 - 1.1e-46 159.1 0.0 1.2e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SpoU_methylase PF00588.19 EOO02066.1 - 0.014 15.6 0.0 0.22 11.7 0.0 2.1 1 1 1 2 2 2 0 SpoU rRNA Methylase family NuiA PF07924.11 EOO02066.1 - 0.043 14.2 0.0 0.078 13.4 0.0 1.4 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein Dioxygenase_C PF00775.21 EOO02066.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Dioxygenase dCMP_cyt_deam_1 PF00383.23 EOO02067.1 - 1e-08 34.9 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EOO02067.1 - 7.5e-06 25.7 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EOO02067.1 - 0.069 13.2 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase APOBEC2 PF18772.1 EOO02067.1 - 0.09 12.8 0.5 2.6 8.0 0.5 2.0 1 1 0 1 1 1 0 APOBEC2 NAD1 PF18778.1 EOO02067.1 - 0.24 11.4 0.6 2 8.5 0.6 2.0 1 1 0 1 1 1 0 Novel AID APOBEC clade 1 DUF2417 PF10329.9 EOO02068.1 - 3e-44 151.2 2.6 4.1e-44 150.8 2.6 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) p450 PF00067.22 EOO02069.1 - 1.6e-73 248.1 0.0 2e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3045 PF11243.8 EOO02069.1 - 0.0019 18.3 0.0 0.0044 17.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3045) DEAD PF00270.29 EOO02070.1 - 5.3e-48 163.1 0.0 3.1e-47 160.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EOO02070.1 - 1e-26 93.4 0.0 2.7e-26 92.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO02070.1 - 0.0085 16.1 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Arf PF00025.21 EOO02071.1 - 1.5e-79 265.5 0.2 1.7e-79 265.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EOO02071.1 - 1.7e-14 54.1 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EOO02071.1 - 2e-14 53.4 0.0 2.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EOO02071.1 - 2.7e-13 49.8 1.4 2.2e-09 36.9 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EOO02071.1 - 3.4e-13 49.5 0.0 3.8e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EOO02071.1 - 1.3e-10 41.0 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EOO02071.1 - 2.9e-06 27.3 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EOO02071.1 - 0.01 15.2 1.0 0.03 13.6 1.0 1.8 1 1 0 1 1 1 0 6-phosphofructo-2-kinase LSM PF01423.22 EOO02072.1 - 5.5e-18 64.4 0.0 6.7e-18 64.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain ORC3_N PF07034.11 EOO02073.1 - 3.4e-36 125.0 7.2 1.6e-35 122.8 2.8 2.4 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 EOO02073.1 - 1.9e-27 96.1 0.1 1.4e-16 60.8 0.0 2.5 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal O-FucT PF10250.9 EOO02074.1 - 1.4e-11 44.7 0.0 3.3e-11 43.5 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase NPL4 PF05021.15 EOO02075.1 - 4.4e-139 463.1 0.0 5.7e-139 462.7 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EOO02075.1 - 8.4e-67 223.8 0.1 1.4e-66 223.1 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EOO02075.1 - 0.0021 18.5 0.0 0.0063 17.0 0.0 1.8 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 HMG_box_2 PF09011.10 EOO02076.1 - 5.2e-11 43.0 3.3 2.8e-07 31.0 0.6 3.0 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 EOO02076.1 - 4.3e-10 39.9 11.6 7.4e-10 39.1 0.2 3.4 3 0 0 3 3 3 2 HMG (high mobility group) box FAD_binding_2 PF00890.24 EOO02077.1 - 7.8e-122 407.3 3.8 9.6e-122 407.0 3.8 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EOO02077.1 - 1.6e-43 147.7 0.5 2.4e-43 147.2 0.5 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EOO02077.1 - 0.00012 21.4 0.6 0.042 13.1 0.3 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EOO02077.1 - 0.00013 21.3 0.1 0.061 12.6 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 EOO02077.1 - 0.00037 19.7 0.8 0.17 11.0 1.4 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EOO02077.1 - 0.0056 16.0 2.3 0.0081 15.4 0.1 2.2 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 EOO02077.1 - 0.12 12.0 0.9 0.2 11.2 0.9 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase CPSase_L_D2 PF02786.17 EOO02078.1 - 2.3e-109 363.8 0.0 8.2e-85 283.6 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EOO02078.1 - 2e-40 137.9 0.0 6.9e-40 136.2 0.0 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EOO02078.1 - 1.5e-21 76.8 0.0 1.4e-09 37.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EOO02078.1 - 2e-18 66.7 0.7 6.5e-08 32.3 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EOO02078.1 - 5.7e-11 42.3 0.0 0.00052 19.8 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 EOO02078.1 - 8.6e-07 28.9 0.3 0.062 13.1 0.0 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 EOO02078.1 - 3.7e-06 27.1 0.1 0.13 12.3 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 EOO02078.1 - 1.1e-05 25.0 0.1 0.018 14.5 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 EOO02078.1 - 3e-05 23.7 0.1 0.018 14.7 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Epimerase PF01370.21 EOO02078.1 - 0.072 12.5 0.0 0.23 10.9 0.0 1.8 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PY_rept_46 PF09689.10 EOO02079.1 - 0.3 11.7 3.3 6 7.5 0.3 2.8 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) Sec66 PF09802.9 EOO02080.1 - 1.1e-82 275.9 0.2 1.3e-82 275.7 0.2 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 OmpH PF03938.14 EOO02080.1 - 0.045 14.1 1.0 0.065 13.6 1.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PEP-utilisers_N PF05524.13 EOO02080.1 - 0.23 11.7 2.6 0.41 10.8 2.7 1.5 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal FUSC PF04632.12 EOO02080.1 - 2 6.9 4.1 2.6 6.5 4.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Kinesin PF00225.23 EOO02081.1 - 1.5e-95 319.9 1.6 1.5e-95 319.9 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EOO02081.1 - 4.1e-22 78.7 0.0 2.7e-21 76.1 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 EOO02081.1 - 0.0077 16.1 0.6 0.0077 16.1 0.6 3.9 4 0 0 4 4 4 2 Coiled-coil N-terminus of cGMP-dependent protein kinase Macoilin PF09726.9 EOO02081.1 - 0.094 11.3 15.7 0.16 10.5 15.7 1.3 1 0 0 1 1 1 0 Macoilin family TFB6 PF17110.5 EOO02081.1 - 0.32 10.7 6.7 1.2 8.8 6.7 2.0 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Tho2 PF11262.8 EOO02081.1 - 2.1 7.5 4.8 3.6 6.7 4.8 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 GAS PF13851.6 EOO02081.1 - 3 7.1 21.2 0.88 8.9 13.0 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 EOO02081.1 - 4.2 6.6 17.1 0.35 10.2 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Proteasome PF00227.26 EOO02082.1 - 1.1e-47 162.0 0.2 1.4e-47 161.7 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EOO02082.1 - 4.2e-13 48.4 0.1 4.2e-13 48.4 0.1 1.9 3 0 0 3 3 3 1 Proteasome beta subunits C terminal DUF836 PF05768.14 EOO02084.1 - 4.6e-10 39.8 0.0 5.7e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 EOO02084.1 - 0.028 14.6 0.1 0.057 13.6 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin C4 PF01413.19 EOO02085.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal tandem repeated domain in type 4 procollagen CHORD PF04968.12 EOO02086.1 - 1e-49 167.0 21.8 9.8e-26 90.3 7.7 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 EOO02086.1 - 3.2e-13 50.5 0.0 5e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF4187 PF13821.6 EOO02087.1 - 4.8e-22 77.5 2.6 1.4e-21 76.0 2.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EOO02087.1 - 1.5e-08 34.4 1.5 2.9e-08 33.5 1.5 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EOO02087.1 - 0.032 14.3 0.6 0.032 14.3 0.6 2.1 2 0 0 2 2 2 0 G-patch domain MRP-S26 PF14943.6 EOO02087.1 - 2.3 8.1 20.2 9.5 6.1 0.1 3.1 3 0 0 3 3 3 0 Mitochondrial ribosome subunit S26 UQ_con PF00179.26 EOO02088.1 - 1.5e-10 40.9 0.9 3.9e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme 3Beta_HSD PF01073.19 EOO02089.1 - 2.8e-66 223.4 0.0 3.3e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EOO02089.1 - 1.2e-29 103.5 0.2 1.6e-29 103.1 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO02089.1 - 3.2e-17 62.9 0.1 4.5e-16 59.2 0.1 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EOO02089.1 - 1.5e-13 50.5 0.1 2e-13 50.1 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EOO02089.1 - 5e-13 48.8 1.3 6.6e-11 41.9 0.3 2.1 1 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EOO02089.1 - 1.5e-09 38.0 0.1 2.3e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EOO02089.1 - 1.8e-07 30.6 0.1 4.3e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EOO02089.1 - 0.00032 20.7 2.8 0.0042 17.0 2.8 2.3 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 EOO02089.1 - 0.004 17.4 0.1 0.0083 16.4 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain DUF3798 PF12683.7 EOO02089.1 - 0.0052 16.2 0.4 0.0084 15.6 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3798) NAD_binding_3 PF03447.16 EOO02089.1 - 0.03 15.0 0.0 0.087 13.5 0.0 1.9 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain tRNA-synt_2 PF00152.20 EOO02089.1 - 0.061 12.4 0.1 2.9 6.9 0.1 2.0 1 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) Glyco_trans_4_2 PF13477.6 EOO02089.1 - 0.12 12.4 0.1 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase 4-like Stk19 PF10494.9 EOO02091.1 - 2.1e-82 276.5 0.0 3e-82 276.0 0.0 1.3 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Sulfate_transp PF00916.20 EOO02091.1 - 3.6e-42 144.5 7.5 6.6e-42 143.6 7.5 1.4 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 EOO02091.1 - 2.1e-14 53.3 0.0 4.4e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 EOO02091.1 - 7.7e-10 38.4 0.0 1.9e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 STAS domain SKI PF01202.22 EOO02092.1 - 0.0023 18.1 0.0 0.0027 17.8 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 EOO02092.1 - 0.0029 18.1 0.0 0.0083 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EOO02092.1 - 0.03 14.5 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_L6e PF01159.19 EOO02093.1 - 8.4e-41 139.0 0.6 1.4e-40 138.3 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e ORC5_C PF14630.6 EOO02093.1 - 0.013 15.0 0.2 0.021 14.4 0.2 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Lsr2 PF11774.8 EOO02093.1 - 3.8 7.7 7.8 3.3 7.9 1.3 2.2 2 0 0 2 2 2 0 Lsr2 CLIP1_ZNF PF16641.5 EOO02094.1 - 4.5e-07 29.6 10.2 0.00024 20.9 1.3 2.6 2 0 0 2 2 2 2 CLIP1 zinc knuckle DUF3584 PF12128.8 EOO02094.1 - 2.7e-05 22.0 22.5 3.5e-05 21.6 22.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 EOO02094.1 - 2.8e-05 24.5 6.6 0.031 14.7 0.5 3.3 4 0 0 4 4 2 2 Nucleopolyhedrovirus P10 protein Filament PF00038.21 EOO02094.1 - 0.00076 19.1 31.0 0.036 13.7 1.2 3.1 2 1 1 3 3 3 2 Intermediate filament protein Fez1 PF06818.15 EOO02094.1 - 0.0056 17.2 12.8 0.0056 17.2 12.8 3.2 1 1 2 3 3 3 2 Fez1 AAA_13 PF13166.6 EOO02094.1 - 0.024 13.3 17.5 0.006 15.3 10.1 2.7 2 1 0 2 2 2 0 AAA domain DUF1664 PF07889.12 EOO02094.1 - 0.17 11.9 14.8 0.8 9.8 3.1 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) zf_PR_Knuckle PF18445.1 EOO02094.1 - 0.21 11.4 3.1 4.9 7.1 0.1 2.4 2 0 0 2 2 2 0 PR zinc knuckle motif MscS_porin PF12795.7 EOO02094.1 - 0.22 11.0 19.7 0.35 10.4 2.8 3.2 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Spc7 PF08317.11 EOO02094.1 - 0.27 10.1 32.3 0.34 9.8 3.6 3.5 1 1 2 4 4 4 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 EOO02094.1 - 0.28 11.0 20.3 0.23 11.3 3.7 4.0 3 1 1 4 4 4 0 Phage minor structural protein GP20 Med4 PF10018.9 EOO02094.1 - 0.29 10.8 16.3 0.044 13.4 2.4 3.0 1 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 FliD_N PF02465.18 EOO02094.1 - 0.32 11.7 5.2 19 6.1 0.6 3.4 2 2 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Glutaredoxin2_C PF04399.13 EOO02094.1 - 0.37 10.6 6.4 5.5 6.8 0.1 2.9 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain BLOC1_2 PF10046.9 EOO02094.1 - 0.38 11.1 18.3 0.089 13.1 4.1 4.2 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TRPM_tetra PF16519.5 EOO02094.1 - 0.43 10.7 16.0 0.95 9.6 3.1 2.6 2 0 0 2 2 2 0 Tetramerisation domain of TRPM SesA PF17107.5 EOO02094.1 - 0.48 10.6 5.5 0.84 9.8 2.2 2.4 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3987 PF13148.6 EOO02094.1 - 0.53 9.2 17.8 0.032 13.3 4.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3987) TPR_MLP1_2 PF07926.12 EOO02094.1 - 0.66 10.0 38.1 0.049 13.7 12.7 4.0 3 1 1 4 4 3 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.12 EOO02094.1 - 0.8 9.7 12.9 1.1 9.3 1.6 3.7 3 1 1 4 4 4 0 Laminin Domain II Fib_alpha PF08702.10 EOO02094.1 - 0.84 9.8 14.8 1.1 9.4 0.9 3.8 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Pkip-1 PF06878.11 EOO02094.1 - 0.91 9.6 7.7 0.6 10.2 2.8 2.4 1 1 1 2 2 2 0 Pkip-1 protein DUF4407 PF14362.6 EOO02094.1 - 0.93 8.8 22.6 1.1e+03 -1.2 22.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 EOO02094.1 - 0.94 9.5 4.1 1.5 8.8 0.9 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3349 PF11829.8 EOO02094.1 - 1.4 9.8 9.4 0.31 11.9 1.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3349) MAD PF05557.13 EOO02094.1 - 1.5 7.1 30.2 0.1 10.9 16.8 2.7 2 1 1 3 3 3 0 Mitotic checkpoint protein DUF948 PF06103.11 EOO02094.1 - 1.9 8.8 10.3 0.79 10.0 3.1 2.9 3 1 0 3 3 2 0 Bacterial protein of unknown function (DUF948) FAM76 PF16046.5 EOO02094.1 - 2.1 7.6 18.4 1.1 8.6 1.5 3.2 2 1 0 3 3 3 0 FAM76 protein zf-CCHC_4 PF14392.6 EOO02094.1 - 2.5 7.9 3.8 31 4.4 0.2 2.3 2 0 0 2 2 2 0 Zinc knuckle T2SSM PF04612.12 EOO02094.1 - 3.5 7.7 8.0 0.94 9.5 0.7 2.7 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein M Sec2p PF06428.11 EOO02094.1 - 4.6 7.3 26.8 0.34 10.9 1.1 4.6 3 1 0 4 4 4 0 GDP/GTP exchange factor Sec2p DHR10 PF18595.1 EOO02094.1 - 6.4 6.9 44.1 2.1 8.4 2.6 4.6 3 1 2 5 5 5 0 Designed helical repeat protein 10 domain DUF3450 PF11932.8 EOO02094.1 - 6.7 5.9 24.7 2.3 7.5 7.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 EOO02094.1 - 7.2 6.7 36.5 0.94 9.5 2.6 5.6 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding HemX PF04375.14 EOO02094.1 - 8.6 5.5 18.4 0.068 12.5 2.7 3.1 2 1 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase Aldedh PF00171.22 EOO02095.1 - 2.5e-109 365.8 0.0 3.1e-109 365.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4070 PF13282.6 EOO02096.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) Rhomboid PF01694.22 EOO02097.1 - 3.8e-22 78.9 3.6 6.8e-22 78.1 3.6 1.3 1 0 0 1 1 1 1 Rhomboid family LAL_C2 PF18603.1 EOO02097.1 - 0.056 13.6 0.3 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 DUF202 PF02656.15 EOO02097.1 - 0.19 12.2 1.9 5.9 7.4 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Glyco_hydro_38N PF01074.22 EOO02098.1 - 3.1e-87 292.6 0.5 5.2e-87 291.9 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EOO02098.1 - 9.3e-60 202.3 0.0 5.7e-59 199.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EOO02098.1 - 3.2e-28 97.7 0.0 6.9e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EOO02098.1 - 8e-12 45.1 0.0 3.5e-11 43.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 EOO02098.1 - 0.041 13.1 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DUF5110 PF17137.4 EOO02098.1 - 0.075 13.3 0.9 0.25 11.6 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5110) DUF3074 PF11274.8 EOO02099.1 - 9.6e-51 172.4 0.4 2.5e-50 171.0 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) Glyco_hydro_125 PF06824.11 EOO02100.1 - 2.8e-180 599.6 0.0 3.6e-180 599.3 0.0 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) He_PIG PF05345.12 EOO02101.1 - 0.027 14.6 2.1 0.19 11.9 0.3 2.6 2 0 0 2 2 2 0 Putative Ig domain Abhydro_lipase PF04083.16 EOO02102.1 - 3.7e-21 74.5 0.0 7.5e-21 73.5 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EOO02102.1 - 5.4e-07 29.5 0.0 1.6e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EOO02102.1 - 0.00072 18.9 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 TFIIA PF03153.13 EOO02103.1 - 0.007 16.4 20.4 0.012 15.6 20.4 1.4 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2362 PF10154.9 EOO02103.1 - 0.015 14.2 0.3 0.021 13.8 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) DUF1367 PF07105.11 EOO02103.1 - 0.02 14.6 0.2 0.03 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) Thioredoxin_12 PF18400.1 EOO02103.1 - 0.11 12.4 0.7 0.16 11.8 0.7 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain DNA_pol_phi PF04931.13 EOO02103.1 - 0.11 10.6 21.1 0.15 10.1 21.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi IFT57 PF10498.9 EOO02103.1 - 0.41 9.6 6.0 0.66 8.9 6.0 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TFIIF_alpha PF05793.12 EOO02103.1 - 1.6 7.3 13.9 2.5 6.6 13.9 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 EOO02103.1 - 1.7 8.0 14.5 3.3 7.0 14.5 1.5 1 0 0 1 1 1 0 SDA1 V-ATPase_G_2 PF16999.5 EOO02103.1 - 5 7.6 10.6 4.6 7.7 8.7 1.9 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Astro_capsid_p PF12226.8 EOO02103.1 - 6.9 5.7 14.2 11 5.1 14.2 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Rep_fac_C PF08542.11 EOO02104.1 - 6.9e-21 74.5 0.0 1.4e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EOO02104.1 - 5.9e-16 59.1 0.0 1.8e-15 57.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EOO02104.1 - 1.5e-12 47.6 0.0 8.9e-08 32.1 0.0 2.6 3 0 0 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.15 EOO02104.1 - 6.1e-10 39.3 0.0 1.8e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 EOO02104.1 - 1.1e-05 25.9 0.1 0.00087 19.7 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EOO02104.1 - 1.3e-05 25.0 0.0 5.2e-05 23.0 0.0 2.0 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 EOO02104.1 - 1.5e-05 25.2 0.1 4.1e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 EOO02104.1 - 1.6e-05 25.2 0.1 0.0021 18.3 0.0 2.9 2 2 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EOO02104.1 - 4.2e-05 23.5 0.0 9e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EOO02104.1 - 0.00039 19.9 0.0 0.027 13.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 EOO02104.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.14 EOO02104.1 - 0.0012 18.8 0.0 0.032 14.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EOO02104.1 - 0.0016 18.2 0.0 0.0038 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EOO02104.1 - 0.0016 18.4 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EOO02104.1 - 0.0026 18.1 0.0 0.017 15.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EOO02104.1 - 0.0029 17.9 0.0 0.0055 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EOO02104.1 - 0.0053 16.0 0.0 0.0083 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 EOO02104.1 - 0.0075 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 EOO02104.1 - 0.015 15.0 0.0 0.067 12.9 0.0 2.1 3 1 0 3 3 2 0 AAA domain AAA_3 PF07726.11 EOO02104.1 - 0.016 15.1 0.0 0.079 12.8 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EOO02104.1 - 0.034 14.1 0.0 0.17 11.9 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 EOO02104.1 - 0.037 14.6 0.0 0.12 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EOO02104.1 - 0.043 13.1 0.0 0.12 11.5 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 EOO02104.1 - 0.055 14.0 0.0 0.08 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain TPM_phosphatase PF04536.14 EOO02104.1 - 0.079 13.1 0.3 3.3 7.9 0.1 2.5 2 0 0 2 2 2 0 TPM domain DUF4863 PF16155.5 EOO02104.1 - 0.08 12.8 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4863) RNA_helicase PF00910.22 EOO02104.1 - 0.092 13.1 0.0 0.24 11.8 0.0 1.8 1 1 0 1 1 1 0 RNA helicase DEAD PF00270.29 EOO02104.1 - 0.15 11.9 0.4 1.8 8.3 0.0 2.5 2 1 0 3 3 3 0 DEAD/DEAH box helicase Proteasome PF00227.26 EOO02105.1 - 2.7e-47 160.7 0.2 3.1e-47 160.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Imm30 PF15565.6 EOO02106.1 - 0.0077 16.3 0.3 0.016 15.3 0.3 1.5 1 0 0 1 1 1 1 Immunity protein 30 HEAT_2 PF13646.6 EOO02106.1 - 0.063 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 HEAT repeats RAP1 PF07218.11 EOO02107.1 - 2.9 6.1 10.1 3.3 5.9 10.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3818 PF12825.7 EOO02108.1 - 1.4e-125 418.9 6.0 2.5e-125 418.0 6.0 1.5 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EOO02108.1 - 7.7e-40 135.9 1.0 1.5e-39 134.9 1.0 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 EOO02108.1 - 3.1e-17 62.6 0.1 5.7e-16 58.5 0.0 3.0 3 1 0 3 3 3 1 PX domain Cwf_Cwc_15 PF04889.12 EOO02108.1 - 0.01 15.6 3.6 0.01 15.6 3.6 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF4443 PF14544.6 EOO02108.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) DUF3381 PF11861.8 EOO02108.1 - 1.2 8.9 8.7 0.12 12.2 3.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) SVIP PF15811.5 EOO02109.1 - 0.73 10.3 16.6 0.32 11.5 10.3 2.2 1 1 1 2 2 2 0 Small VCP/p97-interacting protein ANAPC4_WD40 PF12894.7 EOO02110.1 - 4e-07 30.2 0.1 0.00024 21.3 0.1 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EOO02110.1 - 0.063 14.2 0.0 0.47 11.4 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat NUP214 PF16755.5 EOO02110.1 - 0.12 11.6 0.0 0.5 9.5 0.0 1.9 2 1 0 2 2 2 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 HpcH_HpaI PF03328.14 EOO02111.1 - 1.6e-13 50.3 0.3 1.9e-13 50.1 0.3 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 EOO02111.1 - 0.18 10.9 0.9 0.84 8.7 0.9 1.8 1 1 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Beta_elim_lyase PF01212.21 EOO02112.1 - 8.9e-63 212.3 0.0 1.2e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EOO02112.1 - 0.00015 20.5 0.0 0.00032 19.4 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Thioredoxin_3 PF13192.6 EOO02112.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin domain Anp1 PF03452.14 EOO02113.1 - 5.9e-109 363.5 0.0 6.9e-109 363.3 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 EOO02113.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 AICARFT_IMPCHas PF01808.18 EOO02114.1 - 3.3e-90 302.5 0.0 4.3e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EOO02114.1 - 8.2e-24 83.6 0.0 1.5e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Proteasom_Rpn13 PF04683.13 EOO02116.1 - 1.3e-26 92.9 0.0 5.5e-26 90.9 0.0 2.1 2 0 0 2 2 2 1 Proteasome complex subunit Rpn13 ubiquitin receptor RRM_1 PF00076.22 EOO02116.1 - 1.7e-12 47.0 1.1 5.8e-05 22.8 0.1 3.4 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RPN13_C PF16550.5 EOO02116.1 - 1.6e-09 37.9 0.1 3.4e-08 33.7 0.1 2.3 1 1 0 1 1 1 1 UCH-binding domain L27_2 PF09045.10 EOO02116.1 - 0.1 12.6 0.4 0.23 11.4 0.4 1.5 1 0 0 1 1 1 0 L27_2 RRM_7 PF16367.5 EOO02116.1 - 0.16 12.1 0.0 0.75 9.9 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif Fib_alpha PF08702.10 EOO02117.1 - 0.00091 19.4 1.4 0.0017 18.6 1.4 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DotU PF09850.9 EOO02117.1 - 0.003 17.3 0.1 0.0046 16.7 0.1 1.4 1 0 0 1 1 1 1 Type VI secretion system protein DotU Rootletin PF15035.6 EOO02117.1 - 0.0037 17.3 1.6 0.0081 16.2 0.2 2.1 1 1 2 3 3 3 1 Ciliary rootlet component, centrosome cohesion ZapB PF06005.12 EOO02117.1 - 0.011 16.1 6.5 0.12 12.8 3.7 2.6 2 0 0 2 2 2 0 Cell division protein ZapB DUF2207 PF09972.9 EOO02117.1 - 0.017 13.9 0.1 0.03 13.1 0.1 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Exonuc_VII_L PF02601.15 EOO02117.1 - 0.028 14.0 1.3 0.035 13.7 1.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit MCPsignal PF00015.21 EOO02117.1 - 0.029 14.2 0.8 0.12 12.2 0.5 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain AKNA PF12443.8 EOO02117.1 - 0.033 14.8 0.7 0.23 12.1 0.2 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor Asp5 PF17000.5 EOO02117.1 - 0.038 14.1 3.0 1.6 8.9 0.5 2.3 2 0 0 2 2 2 0 Accessory secretory protein Sec, Asp5 DUF16 PF01519.16 EOO02117.1 - 0.061 13.8 3.7 0.38 11.3 3.7 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF3357 PF11837.8 EOO02117.1 - 0.074 13.5 0.0 0.27 11.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Spc7 PF08317.11 EOO02117.1 - 0.087 11.7 3.4 0.13 11.1 3.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.12 EOO02117.1 - 0.099 13.3 5.8 0.081 13.5 3.0 2.2 2 0 0 2 2 2 0 SlyX DivIC PF04977.15 EOO02117.1 - 0.1 12.4 5.0 0.085 12.6 2.0 2.3 3 0 0 3 3 3 0 Septum formation initiator gpUL132 PF11359.8 EOO02117.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Med4 PF10018.9 EOO02117.1 - 0.14 11.8 1.7 1.1 9.0 0.5 2.4 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 HrpB7 PF09486.10 EOO02117.1 - 0.17 12.2 6.2 0.23 11.9 4.7 1.8 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Snapin_Pallidin PF14712.6 EOO02117.1 - 0.19 12.2 2.1 0.53 10.7 1.1 2.3 1 1 0 2 2 2 0 Snapin/Pallidin DUF2205 PF10224.9 EOO02117.1 - 0.22 11.5 2.3 1.1 9.3 0.4 2.7 3 0 0 3 3 3 0 Short coiled-coil protein EMP24_GP25L PF01105.24 EOO02117.1 - 0.6 10.0 3.3 0.91 9.4 2.9 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SNARE PF05739.19 EOO02117.1 - 3.1 7.9 9.9 7.6 6.6 0.4 3.1 3 0 0 3 3 3 0 SNARE domain Peptidase_C15 PF01470.17 EOO02118.1 - 2.2e-12 47.6 0.0 2.3e-06 28.0 0.0 2.5 2 1 0 2 2 2 2 Pyroglutamyl peptidase CAP_GLY PF01302.25 EOO02119.1 - 2.6e-08 33.7 3.0 4e-08 33.1 3.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain RTC_insert PF05189.13 EOO02120.1 - 8.9e-29 100.0 0.1 1.6e-28 99.3 0.1 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 EOO02120.1 - 2.6e-26 92.2 0.2 3.2e-26 91.9 0.2 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase AAA_2 PF07724.14 EOO02121.1 - 1.1e-43 149.3 0.0 1e-42 146.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EOO02121.1 - 6.4e-36 122.4 2.6 6.4e-36 122.4 2.6 2.5 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EOO02121.1 - 1.7e-26 92.0 0.2 5.1e-26 90.5 0.2 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EOO02121.1 - 3.4e-19 69.6 0.0 3.6e-10 40.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EOO02121.1 - 1.4e-12 47.8 0.0 8.9e-09 35.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EOO02121.1 - 2.2e-10 41.2 4.6 0.00024 21.5 0.6 4.1 2 2 0 2 2 2 2 AAA ATPase domain Sigma54_activat PF00158.26 EOO02121.1 - 2.2e-07 30.7 0.3 0.00046 19.9 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 EOO02121.1 - 3.7e-07 30.5 0.8 0.056 13.7 0.1 3.7 2 2 0 2 2 2 2 AAA domain TniB PF05621.11 EOO02121.1 - 4.5e-06 26.2 0.0 0.0026 17.2 0.1 3.6 3 1 0 3 3 2 1 Bacterial TniB protein AAA_14 PF13173.6 EOO02121.1 - 3.5e-05 23.8 0.0 0.31 11.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EOO02121.1 - 4.7e-05 23.4 0.1 0.25 11.2 0.0 2.6 2 1 0 2 2 2 2 NACHT domain ATPase_2 PF01637.18 EOO02121.1 - 8.3e-05 22.6 4.9 0.41 10.5 0.1 4.1 3 3 2 5 5 3 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EOO02121.1 - 0.00013 21.8 0.2 0.18 11.5 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 EOO02121.1 - 0.00014 21.5 0.0 0.72 9.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 EOO02121.1 - 0.00032 21.2 0.9 0.28 11.7 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_18 PF13238.6 EOO02121.1 - 0.00093 19.7 0.5 0.27 11.8 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 EOO02121.1 - 0.0026 17.9 0.0 1.5 9.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EOO02121.1 - 0.0047 16.9 2.1 1.5 8.7 0.0 3.2 3 1 1 4 4 3 1 RsgA GTPase AAA_24 PF13479.6 EOO02121.1 - 0.0049 16.6 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EOO02121.1 - 0.0055 16.4 0.3 0.42 10.3 0.0 3.3 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 EOO02121.1 - 0.006 17.0 0.0 1 9.8 0.0 3.1 2 1 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 EOO02121.1 - 0.0064 15.9 0.1 2.7 7.3 0.1 3.2 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EOO02121.1 - 0.0092 15.6 0.5 0.21 11.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 EOO02121.1 - 0.0094 16.0 0.0 7.9 6.4 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 EOO02121.1 - 0.01 16.1 0.9 9.9 6.4 0.0 3.7 3 1 0 3 3 3 0 AAA domain SRP54 PF00448.22 EOO02121.1 - 0.01 15.4 0.0 0.59 9.7 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 EOO02121.1 - 0.011 15.7 0.1 6.2 6.8 0.0 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 EOO02121.1 - 0.021 15.0 0.1 3.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 EOO02121.1 - 0.025 13.7 0.3 1.2 8.2 0.2 3.2 3 2 0 3 3 2 0 Protein of unknown function (DUF815) PhoH PF02562.16 EOO02121.1 - 0.032 13.7 0.1 0.75 9.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ERM PF00769.19 EOO02121.1 - 0.036 13.9 9.7 0.062 13.1 9.7 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family PduV-EutP PF10662.9 EOO02121.1 - 0.037 13.8 0.0 0.82 9.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PIF1 PF05970.14 EOO02121.1 - 0.042 13.0 0.0 4.5 6.3 0.0 2.7 3 0 0 3 3 3 0 PIF1-like helicase AAA_19 PF13245.6 EOO02121.1 - 0.094 13.1 1.3 1.6 9.0 0.0 3.1 3 1 0 3 3 2 0 AAA domain AAA_29 PF13555.6 EOO02121.1 - 0.12 12.1 0.1 5.5 6.8 0.0 2.7 3 0 0 3 3 2 0 P-loop containing region of AAA domain OEP PF02321.18 EOO02121.1 - 0.19 11.5 13.1 0.082 12.7 9.6 2.0 2 0 0 2 2 2 0 Outer membrane efflux protein ADIP PF11559.8 EOO02121.1 - 0.36 10.9 10.9 0.78 9.8 10.9 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 EOO02121.1 - 0.45 9.8 4.7 0.73 9.1 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1640 PF07798.11 EOO02121.1 - 0.45 10.5 6.3 1 9.4 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) GrpE PF01025.19 EOO02121.1 - 3.9 7.1 9.5 3.7 7.2 7.5 2.0 2 0 0 2 2 2 0 GrpE DUF4061 PF13270.6 EOO02121.1 - 7.3 7.0 6.9 52 4.2 0.2 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) AAA_23 PF13476.6 EOO02121.1 - 7.5 7.0 18.7 2.5e+02 2.0 0.0 3.3 2 1 0 2 2 2 0 AAA domain DUF848 PF05852.11 EOO02121.1 - 7.6 6.6 10.8 0.99 9.5 5.5 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF3405 PF11885.8 EOO02122.1 - 2.7e-231 768.7 7.3 3.3e-231 768.4 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Epimerase_2 PF02350.19 EOO02122.1 - 0.097 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF1180 PF06679.12 EOO02122.1 - 0.38 11.2 0.0 0.38 11.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Peptidase_M49 PF03571.15 EOO02123.1 - 3.8e-243 807.9 0.0 4.6e-243 807.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 NodZ PF05830.11 EOO02125.1 - 0.22 10.3 1.7 8.4 5.1 0.2 2.2 2 0 0 2 2 2 0 Nodulation protein Z (NodZ) PWWP PF00855.17 EOO02126.1 - 1.3e-14 54.4 0.7 6e-14 52.2 0.0 2.6 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.11 EOO02126.1 - 0.003 17.6 0.4 0.0061 16.6 0.4 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain UPF0565 PF10561.9 EOO02126.1 - 0.78 8.9 2.3 1.3 8.1 2.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Per1 PF04080.13 EOO02127.1 - 1.1e-104 349.8 8.8 1.3e-104 349.5 8.8 1.0 1 0 0 1 1 1 1 Per1-like family SH3BGR PF04908.15 EOO02128.1 - 0.00017 21.7 0.0 0.00044 20.4 0.0 1.7 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein DUF2052 PF09747.9 EOO02128.1 - 4.5 7.3 17.6 6 6.9 8.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) ATP-synt_10 PF05176.14 EOO02130.1 - 6.8e-78 261.5 0.0 7.7e-78 261.3 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Sugar_tr PF00083.24 EOO02133.1 - 1.8e-24 86.5 0.7 2.3e-15 56.4 0.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter A_deaminase PF00962.22 EOO02134.1 - 1.3e-26 93.7 0.0 1.6e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase FAD_binding_4 PF01565.23 EOO02135.1 - 4.1e-22 78.4 1.5 1.1e-21 77.0 1.5 1.8 1 0 0 1 1 1 1 FAD binding domain PIF1 PF05970.14 EOO02136.1 - 1.4e-57 195.5 3.6 1.3e-54 185.8 0.6 2.7 2 1 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 EOO02136.1 - 1.2e-21 77.4 0.0 2.6e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EOO02136.1 - 1.5e-10 41.6 0.0 3.6e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EOO02136.1 - 3e-05 24.3 0.0 7.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EOO02136.1 - 7.1e-05 23.2 0.0 0.00019 21.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EOO02136.1 - 9.6e-05 22.0 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region UvrD_C_2 PF13538.6 EOO02136.1 - 0.00013 21.7 0.1 0.00046 19.9 0.1 2.0 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EOO02136.1 - 0.00013 20.0 0.5 0.0024 15.9 0.0 2.0 2 0 0 2 2 2 1 Helicase AAA_16 PF13191.6 EOO02136.1 - 0.0016 18.9 1.3 0.0023 18.3 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain TEX33 PF15400.6 EOO02136.1 - 0.003 18.0 0.2 0.0077 16.7 0.2 1.6 1 0 0 1 1 1 1 Testis-expressed sequence 33 protein family RNA_helicase PF00910.22 EOO02136.1 - 0.0082 16.5 0.0 0.025 14.9 0.0 1.8 1 0 0 1 1 1 1 RNA helicase RsgA_GTPase PF03193.16 EOO02136.1 - 0.0088 16.0 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 EOO02136.1 - 0.011 14.9 0.1 0.029 13.4 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.22 EOO02136.1 - 0.013 14.7 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 EOO02136.1 - 0.015 15.0 0.0 0.015 15.0 0.0 2.0 2 0 0 2 2 1 0 P-loop containing region of AAA domain NACHT PF05729.12 EOO02136.1 - 0.017 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 EOO02136.1 - 0.034 13.6 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 1 0 PhoH-like protein ABC_tran PF00005.27 EOO02136.1 - 0.035 14.6 0.0 0.17 12.4 0.0 2.2 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EOO02136.1 - 0.037 14.0 0.2 0.36 10.8 0.2 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AFG1_ATPase PF03969.16 EOO02136.1 - 0.046 12.6 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase AAA_14 PF13173.6 EOO02136.1 - 0.06 13.4 0.0 0.24 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EOO02136.1 - 0.074 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 EOO02136.1 - 0.09 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 EOO02136.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EOO02136.1 - 0.11 12.5 0.0 0.61 10.0 0.0 2.3 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.26 EOO02136.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain SH3_13 PF18335.1 EOO02136.1 - 0.13 12.1 0.1 0.53 10.2 0.0 2.0 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain YjeF_N PF03853.15 EOO02137.1 - 3.4e-39 134.5 0.0 4.9e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 EOO02137.1 - 8.9e-12 45.8 0.3 8.9e-12 45.8 0.3 2.2 2 0 0 2 2 2 1 FDF domain ADH_N PF08240.12 EOO02138.1 - 8.6e-24 83.5 4.0 1.5e-23 82.8 4.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EOO02138.1 - 1.7e-14 53.9 0.2 3.6e-14 52.9 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EOO02138.1 - 7e-05 22.3 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EOO02138.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Gp_dh_N PF00044.24 EOO02138.1 - 0.16 12.3 0.0 13 6.2 0.0 2.4 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Adenine_deam_C PF13382.6 EOO02139.1 - 7.8e-52 175.0 0.0 1.7e-51 173.9 0.0 1.5 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.20 EOO02139.1 - 3.4e-18 66.1 0.0 4.7e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EOO02139.1 - 4.4e-09 36.3 0.9 0.00037 20.1 0.1 2.4 2 0 0 2 2 2 2 Amidohydrolase family Trypsin_2 PF13365.6 EOO02140.1 - 3.3e-06 28.1 0.1 5.8e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EOO02140.1 - 2.8e-05 24.0 0.2 8.1e-05 22.5 0.2 1.6 1 1 0 1 1 1 1 Trypsin MapZ_C2 PF18708.1 EOO02140.1 - 0.11 12.8 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 MapZ extracellular C-terminal domain 2 Sugar_tr PF00083.24 EOO02141.1 - 5.6e-40 137.6 14.7 6.1e-40 137.4 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO02141.1 - 1.9e-12 46.8 21.9 1.2e-11 44.1 22.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily GP41 PF00517.17 EOO02141.1 - 0.034 14.0 3.2 0.48 10.3 0.2 2.3 2 0 0 2 2 2 0 Retroviral envelope protein Scs3p PF10261.9 EOO02142.1 - 1.3e-76 257.4 5.7 1.7e-76 257.0 5.7 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM ATP_transf PF09830.9 EOO02142.1 - 1.5e-18 66.7 0.0 3e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase COesterase PF00135.28 EOO02143.1 - 2.6e-49 168.5 0.2 6.2e-26 91.3 0.0 3.0 1 1 2 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.13 EOO02143.1 - 1.5e-08 34.7 0.2 3e-06 27.2 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M43 PF05572.13 EOO02143.1 - 0.12 12.2 0.9 8.8 6.2 0.1 2.4 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A Oxidored_FMN PF00724.20 EOO02145.1 - 2.8e-33 115.6 0.0 3e-27 95.8 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EOO02145.1 - 0.0004 19.6 0.1 0.035 13.2 0.0 2.3 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) DUF1382 PF07131.11 EOO02145.1 - 0.0048 16.9 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1382) MTHFR PF02219.17 EOO02145.1 - 0.075 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase AP_endonuc_2 PF01261.24 EOO02145.1 - 0.18 11.3 0.2 14 5.0 0.0 2.3 1 1 0 2 2 2 0 Xylose isomerase-like TIM barrel WD40 PF00400.32 EOO02146.1 - 1.9e-30 104.4 16.0 2.3e-06 28.2 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 EOO02146.1 - 4.2e-10 39.3 0.5 9.4e-10 38.2 0.5 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EOO02146.1 - 6.5e-07 29.6 0.2 0.022 15.1 0.0 4.7 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 EOO02146.1 - 1.4e-06 28.0 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 EOO02146.1 - 8.5e-05 21.4 0.3 1.3 7.6 0.0 3.4 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EOO02146.1 - 0.0052 15.4 0.0 0.013 14.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome D1 heme domain F-box_4 PF15966.5 EOO02146.1 - 0.028 14.3 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 F-box Ge1_WD40 PF16529.5 EOO02146.1 - 0.039 12.9 0.3 0.14 11.1 0.0 2.1 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 EOO02146.1 - 0.11 12.1 0.0 0.43 10.1 0.0 2.0 1 1 0 1 1 1 0 PQQ-like domain STE PF02200.16 EOO02146.1 - 0.21 12.0 0.9 3.8 8.0 0.1 2.8 3 0 0 3 3 3 0 STE like transcription factor Pectate_lyase_3 PF12708.7 EOO02148.1 - 2.1e-104 348.0 14.1 8.1e-87 290.6 8.9 2.7 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EOO02148.1 - 6.7e-07 28.9 4.3 0.0037 16.9 0.3 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DUF4957 PF16318.5 EOO02148.1 - 0.7 9.8 3.5 18 5.2 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4957) ABC_tran PF00005.27 EOO02149.1 - 6.4e-50 169.2 0.4 8.4e-30 104.1 0.0 3.5 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 EOO02149.1 - 1.8e-20 73.7 26.8 6.1e-20 72.0 6.4 3.3 3 1 1 4 4 4 2 ABC transporter transmembrane region AAA_29 PF13555.6 EOO02149.1 - 7.4e-06 25.6 1.3 0.07 12.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EOO02149.1 - 8.6e-06 25.3 5.3 1.4 8.3 0.9 4.1 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EOO02149.1 - 1e-05 25.6 1.9 0.11 12.5 0.1 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EOO02149.1 - 9.4e-05 22.4 3.7 0.26 11.0 0.0 4.1 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ATP_bind_1 PF03029.17 EOO02149.1 - 0.00049 19.9 1.5 0.045 13.5 0.0 3.5 4 0 0 4 4 3 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EOO02149.1 - 0.0021 18.5 0.1 0.8 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 EOO02149.1 - 0.0036 17.4 2.9 0.024 14.7 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 EOO02149.1 - 0.017 15.1 0.2 5.1 7.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 EOO02149.1 - 0.026 15.0 10.1 0.17 12.3 0.0 3.7 4 0 0 4 4 4 0 AAA domain MeaB PF03308.16 EOO02149.1 - 0.034 13.1 1.4 3.4 6.6 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 EOO02149.1 - 0.046 13.0 1.3 5.3 6.3 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 EOO02149.1 - 0.059 13.1 5.0 0.45 10.2 0.1 2.8 3 0 0 3 3 3 0 AAA domain DUF2178 PF09946.9 EOO02149.1 - 0.09 13.0 1.8 0.31 11.2 1.8 1.9 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) Roc PF08477.13 EOO02149.1 - 0.11 12.7 0.3 29 4.9 0.1 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 EOO02149.1 - 0.12 11.5 0.1 10 5.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_15 PF13175.6 EOO02149.1 - 0.16 11.7 1.8 6.9 6.3 0.0 2.9 4 0 0 4 4 3 0 AAA ATPase domain Dynamin_N PF00350.23 EOO02149.1 - 0.21 11.6 7.5 0.39 10.8 0.9 2.9 3 0 0 3 3 2 0 Dynamin family DUF2207 PF09972.9 EOO02149.1 - 0.25 10.1 2.7 0.51 9.0 0.1 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) TrwB_AAD_bind PF10412.9 EOO02149.1 - 0.42 9.5 2.2 3.6 6.4 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 EOO02149.1 - 3.2 8.0 5.5 15 5.9 0.2 3.2 3 1 0 3 3 3 0 AAA domain Polysacc_deac_1 PF01522.21 EOO02150.1 - 1.6e-14 53.8 0.0 2.5e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Ribosomal_L5 PF00281.19 EOO02150.1 - 0.17 12.3 0.0 2.8 8.4 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L5 DIOX_N PF14226.6 EOO02151.1 - 2.2e-28 99.4 0.1 3.2e-28 98.9 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EOO02151.1 - 5.8e-22 78.1 0.0 1.4e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Myb_DNA-binding PF00249.31 EOO02152.1 - 0.057 13.6 1.1 0.34 11.1 0.3 2.7 2 1 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EOO02152.1 - 0.084 13.3 0.1 0.54 10.7 0.1 2.2 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain VCBS PF13517.6 EOO02153.1 - 5e-37 126.3 55.0 4e-12 46.6 3.2 8.2 3 2 5 8 8 8 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 EOO02153.1 - 2.6e-12 46.5 4.3 0.52 9.7 0.1 6.5 4 2 2 6 6 6 6 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 EOO02153.1 - 0.0004 20.5 32.6 0.048 13.8 0.1 6.9 7 0 0 7 7 7 4 FG-GAP repeat Dockerin_1 PF00404.18 EOO02153.1 - 0.013 15.7 7.2 4.7 7.5 0.0 5.3 5 0 0 5 5 5 0 Dockerin type I domain GW PF13457.6 EOO02153.1 - 0.04 14.5 0.2 1e+02 3.6 0.3 3.8 3 0 0 3 3 3 0 GW (Gly-Tryp) dipeptide domain PliI PF16743.5 EOO02153.1 - 0.21 11.3 0.6 16 5.2 0.1 3.8 4 1 1 5 5 5 0 Periplasmic lysozyme inhibitor of I-type lysozyme p450 PF00067.22 EOO02154.1 - 1.4e-39 136.1 0.0 1.8e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_61 PF03443.14 EOO02157.1 - 4.8e-54 183.4 0.1 7e-54 182.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RTA1 PF04479.13 EOO02158.1 - 2.5e-68 229.7 12.1 3.4e-68 229.3 12.1 1.2 1 0 0 1 1 1 1 RTA1 like protein SAD_SRA PF02182.17 EOO02159.1 - 5e-36 123.8 0.1 8.7e-36 123.0 0.1 1.4 1 0 0 1 1 1 1 SAD/SRA domain MFS_1 PF07690.16 EOO02160.1 - 4.5e-35 121.2 50.0 2.4e-34 118.8 48.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO02160.1 - 8.9e-05 21.5 15.7 8.9e-05 21.5 15.7 3.8 3 2 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 EOO02160.1 - 0.002 17.1 25.5 0.011 14.6 11.0 2.2 2 0 0 2 2 2 2 MFS_1 like family DUF917 PF06032.12 EOO02161.1 - 2.7e-124 414.6 0.4 5.4e-124 413.6 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 EOO02161.1 - 1.1e-31 110.3 0.9 1.4e-28 100.1 0.2 2.3 1 1 1 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EOO02161.1 - 1e-09 38.4 0.9 2.3e-07 30.7 0.2 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region StbA PF06406.11 EOO02161.1 - 0.0012 18.1 0.1 0.79 8.9 0.0 2.4 2 0 0 2 2 2 2 StbA protein MreB_Mbl PF06723.13 EOO02161.1 - 0.0029 16.5 1.2 0.29 9.9 0.0 2.6 2 1 0 2 2 2 2 MreB/Mbl protein MutL PF13941.6 EOO02161.1 - 0.0042 15.8 0.0 0.0094 14.6 0.0 1.5 1 0 0 1 1 1 1 MutL protein adh_short_C2 PF13561.6 EOO02162.1 - 1.2e-54 185.4 0.0 1.3e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO02162.1 - 9e-43 146.0 0.0 1.1e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO02162.1 - 1.5e-08 34.8 0.0 2e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO02162.1 - 0.0003 20.4 0.0 0.0014 18.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EOO02162.1 - 0.0036 16.6 0.0 0.0068 15.7 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AA_permease_2 PF13520.6 EOO02163.1 - 2.1e-71 241.0 24.2 2.9e-71 240.5 24.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EOO02163.1 - 2.2e-15 56.2 21.2 4e-15 55.4 21.2 1.3 1 1 0 1 1 1 1 Amino acid permease CSG2 PF16965.5 EOO02163.1 - 0.24 10.3 0.7 0.76 8.7 0.4 1.9 2 0 0 2 2 2 0 Ceramide synthase regulator Methyltransf_2 PF00891.18 EOO02164.1 - 2.2e-15 56.5 0.0 3.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Sugar_tr PF00083.24 EOO02165.1 - 4.7e-113 378.4 18.2 5.6e-113 378.2 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO02165.1 - 5.8e-25 88.0 24.5 1.1e-16 60.8 1.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EOO02165.1 - 0.036 12.4 5.3 0.062 11.6 4.4 1.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family EF-G-binding_N PF07299.11 EOO02165.1 - 1.4 9.5 2.9 4.6 7.8 0.1 2.3 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Epimerase PF01370.21 EOO02166.1 - 1.5e-13 50.8 0.0 3.5e-13 49.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO02166.1 - 3.4e-08 33.3 0.1 8.9e-08 31.9 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EOO02166.1 - 9.4e-06 24.8 0.0 1.3e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EOO02166.1 - 1.3e-05 24.9 0.9 3e-05 23.7 0.9 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO02166.1 - 1.4e-05 25.1 0.3 3.3e-05 23.8 0.3 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EOO02166.1 - 0.0092 15.2 0.1 0.42 9.7 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 EOO02166.1 - 0.032 14.1 0.6 1.9 8.4 0.1 2.2 2 0 0 2 2 2 0 KR domain adh_short PF00106.25 EOO02166.1 - 0.046 13.2 0.2 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 EOO02166.1 - 0.13 11.4 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_18 PF00704.28 EOO02167.1 - 9.2e-45 153.7 3.0 1.7e-44 152.9 3.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.6 EOO02167.1 - 1.6e-29 102.2 1.2 1.6e-29 102.2 1.2 3.4 4 0 0 4 4 4 1 Pathogen effector; putative necrosis-inducing factor Chitin_bind_1 PF00187.19 EOO02167.1 - 7.9e-05 23.1 9.2 7.9e-05 23.1 9.2 2.7 2 1 0 2 2 2 1 Chitin recognition protein TauD PF02668.16 EOO02168.1 - 2.3e-47 162.0 0.2 3.5e-47 161.5 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DIOX_N PF14226.6 EOO02169.1 - 1.8e-16 61.0 0.3 4.2e-16 59.7 0.1 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EOO02169.1 - 2.1e-09 37.7 0.0 3e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FerB PF08150.12 EOO02169.1 - 0.027 15.0 0.0 0.046 14.3 0.0 1.3 1 0 0 1 1 1 0 FerB (NUC096) domain Peptidase_S10 PF00450.22 EOO02171.1 - 1.8e-38 133.0 0.8 2.3e-38 132.7 0.8 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.16 EOO02172.1 - 1.7 7.5 15.7 2.1 7.2 12.5 1.9 1 1 0 1 1 1 0 Major Facilitator Superfamily GFA PF04828.14 EOO02173.1 - 0.031 14.6 0.1 0.062 13.6 0.1 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme p450 PF00067.22 EOO02174.1 - 5.2e-52 177.1 0.0 7e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_3 PF00202.21 EOO02175.1 - 1.2e-117 393.0 0.0 1.4e-117 392.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EOO02175.1 - 0.056 12.6 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Methyltransf_23 PF13489.6 EOO02176.1 - 3.7e-20 72.4 0.0 5.5e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO02176.1 - 8e-12 45.7 0.0 1.7e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO02176.1 - 3.3e-10 40.6 0.0 1.4e-09 38.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO02176.1 - 4e-10 39.7 0.0 3.1e-09 36.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO02176.1 - 1.5e-08 35.2 0.0 2.8e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EOO02176.1 - 0.0013 18.5 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EOO02176.1 - 0.0018 17.9 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EOO02176.1 - 0.003 17.0 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.19 EOO02176.1 - 0.0092 16.1 0.0 0.023 14.8 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 EOO02176.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EOO02176.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 EOO02176.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) BUD22 PF09073.10 EOO02177.1 - 5.9e-99 332.3 32.8 6.7e-99 332.1 32.8 1.0 1 0 0 1 1 1 1 BUD22 Peptidase_M20 PF01546.28 EOO02178.1 - 1.4e-27 96.8 0.1 1.9e-27 96.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EOO02178.1 - 9.3e-07 28.7 0.1 1.7e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EOO02178.1 - 0.071 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 UCH_1 PF13423.6 EOO02179.1 - 4.9e-82 276.1 0.0 1.1e-81 274.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EOO02179.1 - 9.7e-22 78.3 0.0 2.3e-21 77.0 0.0 1.7 2 0 0 2 2 2 1 Exonuclease ANAPC4_WD40 PF12894.7 EOO02179.1 - 0.0037 17.5 0.1 5.3 7.4 0.0 3.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain YojJ PF10372.9 EOO02179.1 - 0.087 12.9 0.0 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Filament PF00038.21 EOO02181.1 - 1.1e-07 31.7 140.6 0.069 12.7 32.2 6.5 1 1 4 5 5 5 5 Intermediate filament protein Spc7 PF08317.11 EOO02181.1 - 0.0001 21.3 171.1 0.0077 15.2 6.9 8.0 1 1 7 8 8 8 4 Spc7 kinetochore protein ATG16 PF08614.11 EOO02181.1 - 0.00054 20.2 33.3 0.00054 20.2 33.3 8.7 1 1 7 8 8 8 2 Autophagy protein 16 (ATG16) SlyX PF04102.12 EOO02181.1 - 0.04 14.5 0.5 0.04 14.5 0.5 12.2 7 5 6 13 13 13 0 SlyX Fib_alpha PF08702.10 EOO02181.1 - 0.058 13.6 0.2 0.058 13.6 0.2 9.2 2 1 6 10 10 10 0 Fibrinogen alpha/beta chain family Ovate PF04844.13 EOO02181.1 - 0.13 12.3 0.3 0.41 10.7 0.3 1.9 1 0 0 1 1 1 0 Transcriptional repressor, ovate DUF1541 PF07563.11 EOO02181.1 - 0.39 10.6 2.4 3.8 7.5 0.1 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1541) SNF2_N PF00176.23 EOO02182.1 - 1.7e-67 227.7 0.3 6.3e-62 209.3 0.0 3.3 2 1 1 3 3 3 3 SNF2 family N-terminal domain Helicase_C PF00271.31 EOO02182.1 - 1.4e-16 60.8 0.0 3.9e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO02182.1 - 9.5e-05 22.5 0.0 0.00039 20.5 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AP-5_subunit_s1 PF15001.6 EOO02182.1 - 0.14 12.2 0.6 0.3 11.1 0.6 1.5 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 CTP_synth_N PF06418.14 EOO02183.1 - 1.3e-124 414.8 1.6 1.9e-124 414.3 1.6 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EOO02183.1 - 3e-55 186.9 0.0 4.8e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EOO02183.1 - 1.2e-05 25.2 0.0 4.3e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 EOO02183.1 - 0.0045 17.1 0.0 0.0097 16.0 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2469 PF10611.9 EOO02183.1 - 0.17 12.5 0.0 0.38 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2469) adh_short PF00106.25 EOO02184.1 - 6.1e-16 58.5 0.0 1.3e-13 50.9 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EOO02184.1 - 0.0038 17.1 0.2 0.0058 16.6 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EOO02184.1 - 0.0045 16.6 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 EOO02184.1 - 0.047 12.8 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FAD_binding_3 PF01494.19 EOO02185.1 - 4.5e-11 42.6 0.1 1e-10 41.4 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EOO02185.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase SE PF08491.10 EOO02185.1 - 0.027 13.5 0.0 0.49 9.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.14 EOO02185.1 - 0.19 10.9 0.1 0.62 9.2 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TRAUB PF08164.12 EOO02186.1 - 1.5e-29 102.3 0.1 1.5e-29 102.3 0.1 2.5 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EOO02186.1 - 5e-27 95.3 3.7 5e-27 95.3 3.7 2.3 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor PKcGMP_CC PF16808.5 EOO02187.1 - 0.0027 17.5 6.1 0.0027 17.5 6.1 2.9 3 0 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase MerR-DNA-bind PF09278.11 EOO02187.1 - 0.083 13.4 1.2 0.083 13.4 1.2 3.1 2 1 1 3 3 3 0 MerR, DNA binding Spc7 PF08317.11 EOO02187.1 - 0.084 11.7 13.5 0.11 11.4 13.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Nup88 PF10168.9 EOO02187.1 - 0.42 8.4 12.3 0.48 8.2 12.3 1.0 1 0 0 1 1 1 0 Nuclear pore component DUF2992 PF11208.8 EOO02187.1 - 0.84 9.9 13.8 1.3 9.3 13.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Pox_A_type_inc PF04508.12 EOO02187.1 - 3.7 7.6 10.2 30 4.7 0.6 3.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat TMPIT PF07851.13 EOO02187.1 - 6.8 5.8 7.6 8.9 5.5 7.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein Tudor_3 PF18115.1 EOO02188.1 - 1e-06 28.4 0.1 1.8e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EOO02188.1 - 6.9e-05 22.9 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 EOO02188.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Tudor_2 PF18104.1 EOO02188.1 - 0.17 11.6 0.0 0.5 10.1 0.0 1.8 1 1 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain Aldolase_II PF00596.21 EOO02189.1 - 1.8e-21 76.9 0.1 2.2e-13 50.5 0.1 2.1 1 1 1 2 2 2 2 Class II Aldolase and Adducin N-terminal domain Chal_sti_synt_N PF00195.19 EOO02190.1 - 1.4e-21 77.0 0.2 2.1e-21 76.4 0.2 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 EOO02190.1 - 1.4e-21 77.0 0.0 2.7e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.12 EOO02190.1 - 0.00043 19.7 0.0 0.0008 18.8 0.0 1.5 1 1 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 EOO02190.1 - 0.0011 19.0 0.0 0.0044 17.2 0.0 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EOO02190.1 - 0.0065 16.3 0.2 0.049 13.5 0.2 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Sugar_tr PF00083.24 EOO02191.1 - 9e-71 239.1 10.2 9e-71 239.1 10.2 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO02191.1 - 1.2e-07 31.0 18.9 5.5e-07 28.8 11.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO02192.1 - 2.9e-89 300.0 21.2 3.4e-89 299.8 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO02192.1 - 6.3e-27 94.4 28.9 3.9e-26 91.8 19.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EOO02192.1 - 4.6e-05 21.9 8.7 0.00065 18.1 2.3 2.5 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family PUCC PF03209.15 EOO02192.1 - 0.007 15.4 8.8 0.007 15.4 8.8 2.6 2 1 1 3 3 3 2 PUCC protein VHS PF00790.19 EOO02193.1 - 6.2e-35 120.1 0.4 1.5e-34 118.9 0.0 1.8 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 EOO02193.1 - 4e-16 58.3 0.0 1.1e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EOO02193.1 - 1.3e-15 56.8 0.0 2.6e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EOO02193.1 - 7.7e-15 54.5 0.8 1.3e-14 53.7 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain GAT PF03127.14 EOO02193.1 - 2.8e-11 43.5 4.4 9.1e-11 41.9 1.6 2.7 2 1 1 3 3 3 1 GAT domain UIM PF02809.20 EOO02193.1 - 0.0035 17.2 4.0 0.011 15.6 4.0 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF3361 PF11841.8 EOO02193.1 - 0.042 13.8 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) UNC45-central PF11701.8 EOO02193.1 - 0.094 12.7 0.8 0.32 10.9 0.2 2.0 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central DUF4375 PF14300.6 EOO02193.1 - 3.4 7.9 4.9 1.2 9.4 1.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4375) CK_II_beta PF01214.18 EOO02194.1 - 3.9e-74 248.4 0.0 6.2e-74 247.7 0.0 1.3 1 1 0 1 1 1 1 Casein kinase II regulatory subunit RRN3 PF05327.11 EOO02194.1 - 0.061 11.9 1.5 0.091 11.3 1.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 EOO02194.1 - 2 6.6 5.4 2.9 6.1 5.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Spt5_N PF11942.8 EOO02194.1 - 3.1 8.9 13.2 0.06 14.3 5.5 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.6 EOO02194.1 - 8.4 6.8 9.9 6.3 7.2 3.7 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 EOO02194.1 - 8.4 4.3 5.7 13 3.7 5.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi SET PF00856.28 EOO02196.1 - 0.00039 20.9 0.0 1.3 9.4 0.0 3.0 2 1 0 2 2 2 2 SET domain FTR1 PF03239.14 EOO02197.1 - 4e-85 285.7 3.8 4.7e-85 285.4 3.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family ESSS PF10183.9 EOO02197.1 - 0.22 11.7 0.4 10 6.4 0.0 3.0 1 1 2 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) NuA4 PF09340.10 EOO02198.1 - 0.015 15.2 4.6 0.031 14.1 4.6 1.6 1 1 0 1 1 1 0 Histone acetyltransferase subunit NuA4 PsiA PF06952.11 EOO02198.1 - 0.044 13.0 5.4 0.051 12.8 5.4 1.1 1 0 0 1 1 1 0 PsiA protein DUF4407 PF14362.6 EOO02198.1 - 0.4 10.0 7.2 0.47 9.7 7.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SOBP PF15279.6 EOO02198.1 - 1.6 9.3 3.4 1.9 9.0 3.4 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Glyco_hydro_3_C PF01915.22 EOO02199.1 - 1.2e-57 195.2 0.0 2.1e-57 194.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EOO02199.1 - 4.1e-35 121.7 0.0 6.1e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EOO02199.1 - 1.2e-14 54.1 0.0 8e-14 51.5 0.0 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 EOO02199.1 - 5.7e-13 48.9 0.1 1.6e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 PA14 domain GLEYA PF10528.9 EOO02199.1 - 0.037 14.4 0.1 0.089 13.2 0.1 1.6 1 0 0 1 1 1 0 GLEYA domain FAD-SLDH PF12318.8 EOO02199.1 - 0.16 12.0 0.0 1.4 9.0 0.0 2.0 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Cupin_1 PF00190.22 EOO02201.1 - 3e-18 65.9 0.3 4.6e-18 65.3 0.3 1.2 1 0 0 1 1 1 1 Cupin RRM_1 PF00076.22 EOO02202.1 - 1.9e-08 34.0 0.0 3.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EOO02202.1 - 4.1e-05 23.5 0.0 7.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EOO02202.1 - 0.00042 20.1 0.0 0.00072 19.4 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EOO02202.1 - 0.018 15.1 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif Cu-oxidase_2 PF07731.14 EOO02203.1 - 2.7e-44 150.3 13.2 3.8e-39 133.6 2.4 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EOO02203.1 - 2.4e-38 130.8 9.7 4e-37 126.9 1.4 3.5 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EOO02203.1 - 3.1e-37 128.2 3.7 1.7e-33 116.0 0.7 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.6 EOO02203.1 - 0.0033 17.5 0.0 12 6.1 0.0 3.6 2 1 0 2 2 2 2 Cupredoxin-like domain Self-incomp_S1 PF05938.11 EOO02203.1 - 0.11 13.1 0.0 14 6.3 0.0 2.6 2 0 0 2 2 2 0 Plant self-incompatibility protein S1 LigB PF02900.18 EOO02204.1 - 5.7e-35 120.7 0.0 7.3e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Sugar_tr PF00083.24 EOO02205.1 - 8.2e-33 113.9 23.9 2.2e-18 66.4 10.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO02205.1 - 1.5e-19 70.2 37.0 8.1e-12 44.7 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 EOO02206.1 - 1e-35 123.0 0.0 1.4e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO02206.1 - 7.9e-26 91.0 0.0 4.8e-24 85.2 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO02206.1 - 4.5e-08 33.2 0.4 1.4e-07 31.6 0.2 1.7 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 EOO02206.1 - 0.023 15.0 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EOO02206.1 - 0.028 13.9 0.1 0.18 11.2 0.1 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 EOO02206.1 - 0.048 14.2 0.7 0.092 13.3 0.7 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GTP_EFTU PF00009.27 EOO02207.1 - 1.7e-42 145.1 0.0 2.8e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EOO02207.1 - 1.3e-28 99.5 0.3 4.1e-28 97.9 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EOO02207.1 - 4.5e-09 36.6 2.1 6.8e-09 36.0 0.6 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EOO02207.1 - 0.0015 18.6 0.1 0.0096 16.0 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Mitofilin PF09731.9 EOO02207.1 - 0.27 10.1 10.3 0.42 9.4 10.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FTZ PF03867.14 EOO02207.1 - 0.64 9.5 12.0 1.4 8.4 12.0 1.6 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region TAF4 PF05236.14 EOO02207.1 - 0.65 9.7 6.0 1.5 8.5 6.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Mito_carr PF00153.27 EOO02208.1 - 1.7e-55 184.9 3.2 4.8e-20 71.3 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 EOO02208.1 - 0.0071 16.7 1.3 0.029 14.7 0.6 2.5 2 1 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family PT-VENN PF04829.13 EOO02208.1 - 7 6.8 5.9 13 6.0 0.2 3.1 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif PEPCK_ATP PF01293.20 EOO02209.1 - 1.3e-215 716.4 0.0 1.6e-215 716.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 EOO02209.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EOO02209.1 - 0.19 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain BTB PF00651.31 EOO02210.1 - 3.7e-13 49.7 0.0 2.4e-09 37.4 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain DUF2157 PF09925.9 EOO02211.1 - 0.024 14.4 2.3 0.042 13.6 2.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Phage_term_smal PF05944.12 EOO02212.1 - 0.023 14.7 0.5 0.069 13.1 0.5 1.8 1 0 0 1 1 1 0 Phage small terminase subunit EMC3_TMCO1 PF01956.16 EOO02212.1 - 0.084 12.6 6.1 1.9 8.2 6.0 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF2721 PF11026.8 EOO02212.1 - 0.21 11.5 2.9 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) PTPA PF03095.15 EOO02213.1 - 2.2e-122 408.2 0.0 2.6e-122 408.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Mito_carr PF00153.27 EOO02214.1 - 8.3e-52 173.1 3.6 2.8e-17 62.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SecE PF00584.20 EOO02214.1 - 0.032 14.1 0.1 0.064 13.2 0.1 1.5 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Serine_protease PF18405.1 EOO02214.1 - 0.051 12.7 3.5 0.11 11.6 0.0 2.8 2 1 1 3 3 3 0 Gammaproteobacterial serine protease ABC2_membrane PF01061.24 EOO02215.1 - 3.7e-77 258.5 58.0 9.7e-40 136.2 18.9 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EOO02215.1 - 9.1e-36 123.4 0.0 9e-18 65.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EOO02215.1 - 1.5e-27 95.3 0.1 5.5e-24 83.9 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EOO02215.1 - 1.1e-15 57.9 0.1 5e-15 55.9 0.1 2.2 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EOO02215.1 - 2.1e-06 28.2 0.3 0.027 14.9 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 EOO02215.1 - 2.2e-06 27.7 0.0 0.067 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EOO02215.1 - 5.6e-06 26.6 0.1 0.0079 16.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 EOO02215.1 - 1e-05 26.0 0.0 0.013 15.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EOO02215.1 - 5e-05 23.8 0.0 0.021 15.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EOO02215.1 - 0.00011 22.1 0.0 0.00058 19.8 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EOO02215.1 - 0.00021 21.0 0.2 0.015 15.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EOO02215.1 - 0.00055 19.6 0.1 0.037 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EOO02215.1 - 0.002 18.4 0.0 0.22 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EOO02215.1 - 0.0034 17.7 0.0 1 9.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EOO02215.1 - 0.0095 15.4 0.1 0.29 10.5 0.0 2.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain DnaB_C PF03796.15 EOO02215.1 - 0.012 15.0 0.1 0.22 10.8 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain NACHT PF05729.12 EOO02215.1 - 0.013 15.4 0.5 5.6 6.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 EOO02215.1 - 0.027 14.9 0.1 16 5.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EOO02215.1 - 0.034 13.8 0.6 3.4 7.3 0.4 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EOO02215.1 - 0.035 13.7 2.1 0.9 9.1 0.5 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EOO02215.1 - 0.091 12.8 0.1 5.9 7.0 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EOO02215.1 - 0.1 13.0 1.4 10 6.6 0.0 3.7 5 0 0 5 5 4 0 RNA helicase TsaE PF02367.17 EOO02215.1 - 0.13 12.2 0.3 5.7 7.0 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 EOO02215.1 - 0.14 11.9 0.9 6.4 6.5 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC2_membrane_3 PF12698.7 EOO02215.1 - 0.18 10.9 41.3 0.27 10.3 18.9 2.8 2 1 0 2 2 2 0 ABC-2 family transporter protein AAA_19 PF13245.6 EOO02215.1 - 0.28 11.5 0.8 7 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF3073 PF11273.8 EOO02215.1 - 1.7 9.5 4.2 2 9.2 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) AAA_24 PF13479.6 EOO02215.1 - 1.8 8.2 3.4 16 5.1 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 EOO02215.1 - 2.1 8.8 6.5 0.46 11.0 0.1 2.7 3 0 0 3 3 2 0 AAA domain Glyco_hydro_64 PF16483.5 EOO02216.1 - 8.7e-135 449.7 4.8 1e-134 449.5 4.8 1.1 1 0 0 1 1 1 1 Beta-1,3-glucanase Pertussis_S1 PF02917.14 EOO02216.1 - 0.04 13.7 0.1 0.098 12.4 0.1 1.6 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 ATP-synt_D PF01813.17 EOO02217.1 - 0.0033 17.3 0.1 0.0053 16.6 0.1 1.4 1 1 0 1 1 1 1 ATP synthase subunit D Presenilin PF01080.17 EOO02217.1 - 0.32 9.7 1.4 0.24 10.1 0.1 1.4 2 0 0 2 2 2 0 Presenilin FAD-oxidase_C PF02913.19 EOO02218.1 - 1e-67 228.4 0.0 1.4e-67 228.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EOO02218.1 - 1.7e-36 125.0 0.3 3.3e-36 124.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain LemA PF04011.12 EOO02218.1 - 0.062 13.2 0.2 0.28 11.0 0.0 2.1 3 0 0 3 3 3 0 LemA family Ribosomal_L7Ae PF01248.26 EOO02219.1 - 4.2e-28 96.9 0.8 5.6e-28 96.5 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EOO02219.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain Zn_clus PF00172.18 EOO02220.1 - 2.6e-06 27.4 12.3 5e-06 26.5 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CH PF00307.31 EOO02221.1 - 5.8e-48 161.6 0.3 1.6e-22 79.8 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 EOO02221.1 - 2.8e-24 85.0 0.3 1.4e-23 82.7 0.0 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 EOO02221.1 - 1.1e-11 44.4 0.5 3.1e-06 26.9 0.0 2.9 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.6 EOO02221.1 - 0.00031 20.4 0.2 0.0015 18.3 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain Spectrin PF00435.21 EOO02221.1 - 0.001 19.5 3.8 0.37 11.3 1.5 2.7 2 0 0 2 2 2 2 Spectrin repeat CH_2 PF06294.11 EOO02221.1 - 0.0022 18.1 0.0 0.043 13.9 0.0 2.9 3 0 0 3 3 3 1 CH-like domain in sperm protein EF-hand_7 PF13499.6 EOO02221.1 - 0.0051 17.2 1.3 0.031 14.7 1.3 2.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EOO02221.1 - 0.0054 16.6 0.2 0.046 13.6 0.1 2.4 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EOO02221.1 - 0.059 13.0 0.0 0.2 11.3 0.0 2.0 1 0 0 1 1 1 0 EF hand Sipho_Gp157 PF05565.11 EOO02221.1 - 0.082 12.9 2.5 3.8 7.5 0.2 2.4 2 0 0 2 2 2 0 Siphovirus Gp157 Fib_alpha PF08702.10 EOO02221.1 - 0.11 12.7 0.3 7.6 6.7 0.0 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Flavodoxin_5 PF12724.7 EOO02222.1 - 5.9e-18 65.5 0.0 6.6e-17 62.1 0.0 2.0 1 1 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 EOO02222.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin TCTP PF00838.17 EOO02223.1 - 2.7e-72 242.5 3.7 3e-72 242.4 3.7 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein DUF1421 PF07223.11 EOO02223.1 - 0.048 13.5 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain (DUF1421) PPR_2 PF13041.6 EOO02224.1 - 1.4e-15 57.2 0.0 4.6e-05 23.5 0.0 4.0 4 0 0 4 4 4 3 PPR repeat family PPR_3 PF13812.6 EOO02224.1 - 3.5e-09 36.6 0.0 0.00028 20.9 0.0 3.8 2 2 2 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 EOO02224.1 - 2.1e-08 33.9 1.2 0.047 14.0 0.0 5.2 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 EOO02224.1 - 3.6e-06 26.5 1.7 0.0021 17.5 0.2 2.2 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EOO02224.1 - 0.00027 20.6 0.4 2.7 7.8 0.0 4.1 4 0 0 4 4 4 2 PPR repeat RPM2 PF08579.11 EOO02224.1 - 0.022 15.1 0.0 0.059 13.8 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) DnaB PF00772.21 EOO02224.1 - 0.063 13.4 0.1 3.9 7.6 0.0 2.6 2 1 0 2 2 2 0 DnaB-like helicase N terminal domain TPR_14 PF13428.6 EOO02224.1 - 0.096 13.6 0.5 11 7.2 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat CobN-Mg_chel PF02514.16 EOO02224.1 - 0.096 10.4 0.0 0.1 10.3 0.0 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase ECSIT PF06239.11 EOO02224.1 - 0.15 11.2 0.1 7.6 5.6 0.1 2.1 1 1 1 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway ABM PF03992.16 EOO02225.1 - 0.00095 19.2 0.0 0.0014 18.7 0.0 1.4 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SH3_1 PF00018.28 EOO02226.1 - 3.1e-06 26.7 0.0 5.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EOO02226.1 - 0.00027 20.7 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EOO02226.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Arginase PF00491.21 EOO02227.1 - 1.5e-91 306.8 0.0 1.9e-91 306.5 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EOO02227.1 - 0.029 14.6 0.1 0.049 13.9 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain Lipase_3 PF01764.25 EOO02228.1 - 2.7e-08 33.8 0.1 7.3e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) UPF0227 PF05728.12 EOO02228.1 - 0.021 14.8 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 EOO02228.1 - 0.031 13.6 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EOO02228.1 - 0.038 13.6 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EOO02228.1 - 0.16 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DIOX_N PF14226.6 EOO02229.1 - 7.4e-26 91.2 0.0 1.3e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EOO02229.1 - 2.4e-12 47.2 0.0 4.4e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EOO02229.1 - 0.16 12.9 0.0 22 6.0 0.0 2.3 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily DAO PF01266.24 EOO02230.1 - 5.8e-15 55.7 0.0 1.4e-14 54.5 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EOO02230.1 - 0.00074 19.7 0.3 0.0023 18.1 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EOO02230.1 - 0.0021 17.3 0.0 0.0077 15.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EOO02230.1 - 0.022 13.9 0.2 2 7.4 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EOO02230.1 - 0.029 13.6 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 EOO02230.1 - 0.035 13.5 0.2 0.065 12.6 0.2 1.4 1 0 0 1 1 1 0 ThiF family FAD_binding_2 PF00890.24 EOO02230.1 - 0.14 11.3 0.1 0.33 10.0 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Kelch_1 PF01344.25 EOO02230.1 - 0.18 11.4 0.5 3.4 7.3 0.1 2.8 3 0 0 3 3 3 0 Kelch motif DEAD PF00270.29 EOO02231.1 - 1.2e-40 139.1 0.0 2.1e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EOO02231.1 - 1.8e-30 105.5 0.0 4.3e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO02231.1 - 5.3e-06 26.5 0.0 8.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EOO02231.1 - 0.003 16.4 0.0 0.0049 15.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 EOO02231.1 - 0.021 14.5 0.0 0.088 12.5 0.0 1.8 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Ribosomal_S8 PF00410.19 EOO02232.1 - 5.4e-22 78.1 0.0 7.6e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 zf-C3HC4 PF00097.25 EOO02233.1 - 2.6e-08 33.6 4.7 8.4e-08 32.0 4.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EOO02233.1 - 9.6e-08 31.7 2.9 9.6e-08 31.7 2.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EOO02233.1 - 9.7e-08 31.9 5.3 1.2e-07 31.6 4.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.6 EOO02233.1 - 5.9e-07 29.3 0.3 5.9e-07 29.3 0.3 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EOO02233.1 - 4.2e-06 26.6 3.4 9.9e-06 25.4 3.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EOO02233.1 - 9.6e-06 25.8 7.9 2.3e-05 24.6 7.9 1.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 EOO02233.1 - 2.9e-05 24.1 5.4 9.4e-05 22.5 5.4 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EOO02233.1 - 3.9e-05 23.4 4.3 0.0011 18.8 0.8 2.1 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EOO02233.1 - 0.0014 18.7 1.5 0.01 16.0 1.0 2.1 2 0 0 2 2 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 EOO02233.1 - 0.46 10.4 6.0 4.6 7.2 6.0 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EOO02233.1 - 0.72 9.5 4.4 0.26 10.9 1.4 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 EOO02233.1 - 6 7.2 8.3 5.8 7.3 4.7 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain PUF PF00806.19 EOO02234.1 - 4.5e-64 208.7 11.5 1.6e-08 33.8 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 EOO02234.1 - 0.0027 18.1 4.1 4.3 7.7 0.0 4.3 1 1 2 3 3 3 2 CPL (NUC119) domain sCache_2 PF17200.4 EOO02234.1 - 0.023 14.5 1.0 32 4.3 0.0 4.6 4 1 1 5 5 5 0 Single Cache domain 2 SapB_2 PF03489.17 EOO02234.1 - 0.26 11.4 1.0 8.5 6.6 0.1 2.8 2 0 0 2 2 2 0 Saposin-like type B, region 2 Pet100 PF09803.9 EOO02235.1 - 8.1e-21 74.3 0.5 1e-20 74.0 0.5 1.3 1 1 0 1 1 1 1 Pet100 Nitr_red_bet_C PF14711.6 EOO02235.1 - 0.26 11.0 1.9 0.37 10.5 1.9 1.2 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal His_Phos_2 PF00328.22 EOO02236.1 - 1.5e-16 60.7 0.0 2.4e-14 53.5 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sugar_tr PF00083.24 EOO02237.1 - 5.6e-60 203.5 14.8 4.3e-37 128.0 5.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO02237.1 - 0.00011 21.3 20.2 0.00091 18.2 20.6 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3671 PF12420.8 EOO02237.1 - 0.021 14.9 0.6 0.28 11.3 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function HGTP_anticodon PF03129.20 EOO02238.1 - 3.1e-19 68.9 0.0 1.2e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EOO02238.1 - 2.6e-09 37.3 0.0 2.3e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Amidohydro_2 PF04909.14 EOO02239.1 - 2.5e-05 24.2 0.0 4.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase PGAP1 PF07819.13 EOO02239.1 - 0.00028 20.7 0.0 0.00057 19.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 EOO02239.1 - 0.001 19.0 0.0 0.18 11.7 0.0 2.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EOO02239.1 - 0.0021 18.7 4.3 0.0021 18.7 4.3 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EOO02239.1 - 0.0095 16.1 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 EOO02239.1 - 0.014 14.7 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TatD_DNase PF01026.21 EOO02239.1 - 0.016 14.6 0.0 0.25 10.7 0.0 2.1 2 0 0 2 2 2 0 TatD related DNase Abhydrolase_2 PF02230.16 EOO02239.1 - 0.02 14.7 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF676 PF05057.14 EOO02239.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DnaJ PF00226.31 EOO02242.1 - 9.8e-09 35.2 0.0 2.5e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain FapA PF03961.13 EOO02242.1 - 0.093 11.3 6.7 0.12 10.9 6.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_15 PF13175.6 EOO02242.1 - 0.35 10.5 2.5 0.5 10.0 2.5 1.3 1 1 0 1 1 1 0 AAA ATPase domain SAPS PF04499.15 EOO02242.1 - 3.1 6.5 9.5 3.8 6.2 9.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Paf1 PF03985.13 EOO02243.1 - 9.9e-82 275.2 0.0 1.1e-81 275.0 0.0 1.0 1 0 0 1 1 1 1 Paf1 Pkinase PF00069.25 EOO02244.1 - 1.1e-63 215.1 0.0 1.3e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO02244.1 - 7.2e-36 123.8 0.0 9.7e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EOO02244.1 - 1e-06 28.3 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EOO02244.1 - 0.00012 21.0 0.0 0.00018 20.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EOO02244.1 - 0.0074 15.9 0.0 0.34 10.5 0.0 2.1 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EOO02244.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EOO02244.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 BUD22 PF09073.10 EOO02245.1 - 0.19 11.0 16.8 0.24 10.7 16.8 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EOO02245.1 - 6.6 6.0 16.1 9.3 5.6 16.1 1.3 1 0 0 1 1 1 0 SDA1 WD40 PF00400.32 EOO02246.1 - 1.6e-16 60.4 14.7 0.0028 18.5 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO02246.1 - 1.2e-09 38.3 0.1 0.0076 16.5 0.0 4.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EOO02246.1 - 9.2e-08 31.7 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain PQQ_2 PF13360.6 EOO02246.1 - 0.0043 16.7 0.1 0.079 12.5 0.0 2.6 1 1 1 2 2 2 1 PQQ-like domain PQQ PF01011.21 EOO02246.1 - 0.12 12.3 0.4 30 4.8 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat FA_hydroxylase PF04116.13 EOO02247.1 - 8.9e-22 77.9 15.2 8.9e-22 77.9 15.2 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1640 PF07798.11 EOO02248.1 - 1.9e-47 161.6 5.4 3.1e-47 160.9 5.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Baculo_PEP_C PF04513.12 EOO02248.1 - 0.13 12.3 5.1 0.24 11.5 5.1 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CRAL_TRIO PF00650.20 EOO02249.1 - 6.4e-43 146.2 0.0 8.6e-43 145.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EOO02249.1 - 1.1e-16 60.7 1.9 3.2e-16 59.3 1.9 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EOO02249.1 - 0.15 12.2 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain TruD PF01142.18 EOO02250.1 - 1.8e-57 195.1 0.0 2.4e-54 184.7 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Proteasome PF00227.26 EOO02251.1 - 2e-56 190.5 0.1 3e-56 189.9 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EOO02251.1 - 9.6e-05 22.0 0.7 0.00028 20.5 0.2 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DAO PF01266.24 EOO02252.1 - 0.00017 21.3 0.0 0.0002 21.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HEAT_2 PF13646.6 EOO02253.1 - 4.2e-10 39.9 2.9 0.66 10.4 0.0 6.3 4 2 1 5 5 5 4 HEAT repeats Cnd1 PF12717.7 EOO02253.1 - 3.3e-06 27.2 0.1 6.7 6.7 0.0 5.7 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 UNC45-central PF11701.8 EOO02253.1 - 1.6e-05 24.9 0.5 0.02 14.9 0.0 4.2 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 EOO02253.1 - 6.8e-05 23.4 0.0 0.091 13.4 0.0 4.0 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EOO02253.1 - 0.00034 20.6 20.4 0.15 12.4 0.0 8.2 10 0 0 10 10 10 2 HEAT repeat Resolvase PF00239.21 EOO02253.1 - 0.11 12.6 0.4 1.9 8.6 0.0 3.2 3 1 1 4 4 4 0 Resolvase, N terminal domain MMS19_N PF14500.6 EOO02253.1 - 0.29 10.7 1.9 35 3.9 0.3 3.5 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 EOO02253.1 - 1.6 9.4 22.0 2.6 8.7 0.1 8.2 7 2 2 9 9 9 0 HEAT-like repeat IFRD PF05004.13 EOO02253.1 - 6.8 5.7 15.9 1.5 7.9 0.1 5.2 5 2 0 6 6 6 0 Interferon-related developmental regulator (IFRD) Ribosomal_L19 PF01245.20 EOO02254.1 - 1.9e-13 50.3 0.2 3e-13 49.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 UPA_2 PF17809.1 EOO02254.1 - 0.089 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 UPA domain Rer1 PF03248.13 EOO02255.1 - 1.7e-72 242.7 8.0 9.8e-64 214.2 2.4 2.0 2 0 0 2 2 2 2 Rer1 family DUF1538 PF07556.11 EOO02255.1 - 0.045 13.1 1.0 0.53 9.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1538) AAA_5 PF07728.14 EOO02256.1 - 3.2e-10 40.2 0.0 4.5e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EOO02256.1 - 1.4e-06 28.8 0.0 3e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EOO02256.1 - 1.4e-06 28.5 0.0 6.3e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 EOO02256.1 - 0.00044 20.3 0.1 0.0011 18.9 0.1 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 EOO02256.1 - 0.00058 20.3 0.1 0.96 9.8 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 EOO02256.1 - 0.003 17.3 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EOO02256.1 - 0.0078 15.6 0.0 0.18 11.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EOO02256.1 - 0.013 15.8 0.1 0.084 13.1 0.0 2.3 1 1 0 2 2 2 0 AAA domain AAA_6 PF12774.7 EOO02256.1 - 0.075 12.0 0.0 0.16 10.9 0.0 1.5 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_32 PF13654.6 EOO02256.1 - 0.12 11.1 0.0 0.37 9.5 0.0 1.7 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 EOO02256.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EOO02256.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.7 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.12 EOO02256.1 - 0.17 11.8 0.0 1.4 8.8 0.0 2.3 3 0 0 3 3 3 0 NACHT domain Rotamase_3 PF13616.6 EOO02259.1 - 5.6e-17 62.4 0.5 8.4e-17 61.8 0.3 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EOO02259.1 - 9.6e-16 58.5 0.7 1.4e-15 58.0 0.4 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EOO02259.1 - 0.00024 21.9 1.7 0.00038 21.3 1.7 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain YL1_C PF08265.11 EOO02260.1 - 8.4e-16 57.4 1.5 1.3e-15 56.9 1.5 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.16 EOO02260.1 - 0.033 14.1 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 HIT zinc finger PTPLA PF04387.14 EOO02261.1 - 9e-50 168.6 8.4 1.6e-49 167.8 8.4 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA PALP PF00291.25 EOO02263.1 - 5.6e-66 222.9 0.1 6.9e-66 222.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Sulfatase PF00884.23 EOO02264.1 - 1.6e-28 100.0 0.0 2.1e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 EOO02264.1 - 0.0012 17.5 0.0 0.0021 16.8 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 EOO02264.1 - 0.0062 16.8 0.1 0.014 15.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) ECH_1 PF00378.20 EOO02266.1 - 8.7e-78 261.1 0.0 9.9e-78 260.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EOO02266.1 - 4.3e-37 128.4 0.3 8.7e-36 124.1 0.3 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Thg1 PF04446.12 EOO02266.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 tRNAHis guanylyltransferase Pol_alpha_B_N PF08418.10 EOO02267.1 - 2.9e-69 233.8 0.2 3.3e-40 138.6 0.2 2.2 1 1 1 2 2 2 2 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 EOO02267.1 - 4.3e-30 104.6 0.1 6.9e-30 104.0 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Transcrip_reg PF01709.20 EOO02268.1 - 4.7e-60 203.0 0.2 5.3e-60 202.8 0.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator HTH_psq PF05225.16 EOO02268.1 - 0.25 11.1 0.8 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Catalase PF00199.19 EOO02269.1 - 6.8e-170 565.3 0.2 2.3e-92 310.1 0.5 2.1 1 1 1 2 2 2 2 Catalase Catalase-rel PF06628.12 EOO02269.1 - 2.6e-11 43.6 0.0 5.9e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF865 PF05906.11 EOO02269.1 - 1.4 8.8 4.2 0.67 9.8 0.6 2.3 3 0 0 3 3 3 0 Herpesvirus-7 repeat of unknown function (DUF865) Lipase_GDSL_2 PF13472.6 EOO02270.1 - 1.1e-07 32.5 0.0 2.6e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EOO02270.1 - 0.0018 18.3 0.0 0.0047 16.9 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_transf_90 PF05686.12 EOO02271.1 - 1.8e-12 46.9 8.6 1.9e-11 43.5 8.6 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 90 GCV_T PF01571.21 EOO02272.1 - 1.3e-06 28.0 0.0 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain zf-CHY PF05495.12 EOO02273.1 - 9.2e-06 26.1 15.5 1.8e-05 25.1 15.5 1.5 1 0 0 1 1 1 1 CHY zinc finger HypA PF01155.19 EOO02273.1 - 1.9 8.6 10.6 5.8 7.0 10.5 1.8 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Evr1_Alr PF04777.13 EOO02273.1 - 6.5 7.3 9.2 77 3.9 6.2 2.6 1 1 2 3 3 3 0 Erv1 / Alr family Skp1 PF01466.19 EOO02274.1 - 3.4e-29 100.7 0.4 3.4e-29 100.7 0.4 1.8 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EOO02274.1 - 3.3e-24 84.8 0.1 8.5e-24 83.5 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Mis12 PF05859.12 EOO02275.1 - 5.7e-50 168.9 0.0 8.2e-50 168.4 0.0 1.2 1 0 0 1 1 1 1 Mis12 protein Arf PF00025.21 EOO02276.1 - 1.7e-58 196.9 0.2 4.5e-57 192.3 0.2 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EOO02276.1 - 7.8e-10 39.0 0.1 1.1e-09 38.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EOO02276.1 - 5.6e-08 32.3 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 G-protein alpha subunit Ras PF00071.22 EOO02276.1 - 4.1e-07 29.7 0.0 5.4e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EOO02276.1 - 2.4e-06 27.1 0.0 3e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EOO02276.1 - 2e-05 24.1 0.0 2.4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EOO02276.1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EOO02276.1 - 0.13 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase ERCC3_RAD25_C PF16203.5 EOO02277.1 - 5.9e-120 399.1 2.4 1.4e-119 397.9 2.4 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EOO02277.1 - 6.5e-34 116.8 0.0 4.6e-33 114.1 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO02277.1 - 9.9e-18 64.7 0.1 4.3e-17 62.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EOO02277.1 - 9e-13 48.5 0.1 2.8e-12 47.0 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EOO02277.1 - 9.1e-08 31.2 0.0 1.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Parathyroid PF01279.17 EOO02277.1 - 0.15 12.7 2.2 22 5.7 0.6 2.9 2 0 0 2 2 2 0 Parathyroid hormone family YL1 PF05764.13 EOO02278.1 - 7.5e-73 245.6 34.7 7.5e-73 245.6 34.7 2.8 3 0 0 3 3 3 1 YL1 nuclear protein Tox-ART-HYD1 PF15633.6 EOO02278.1 - 0.49 11.1 2.8 0.37 11.5 0.6 1.9 2 0 0 2 2 2 0 HYD1 signature containing ADP-ribosyltransferase TMEM154 PF15102.6 EOO02279.1 - 0.006 16.5 0.0 0.0087 16.0 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family LapA_dom PF06305.11 EOO02279.1 - 0.025 14.4 0.1 0.039 13.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain GNVR PF13807.6 EOO02279.1 - 0.027 14.4 0.5 0.46 10.4 0.2 2.2 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase P66_CC PF16563.5 EOO02279.1 - 0.044 13.4 1.3 0.088 12.4 1.3 1.4 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 EphA2_TM PF14575.6 EOO02279.1 - 0.082 13.8 0.0 0.22 12.4 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pyr_redox_2 PF07992.14 EOO02280.1 - 1.8e-54 185.0 0.2 2.2e-54 184.7 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EOO02280.1 - 1.7e-24 86.2 0.9 6.5e-20 71.5 0.1 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EOO02280.1 - 1.8e-22 79.7 0.0 4.5e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 EOO02280.1 - 6.8e-09 35.4 0.5 1.7e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EOO02280.1 - 5.6e-06 25.3 1.0 0.011 14.5 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.6 EOO02280.1 - 1.1e-05 24.7 0.0 0.015 14.4 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 EOO02280.1 - 1.4e-05 24.6 0.3 0.015 14.6 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EOO02280.1 - 4.3e-05 22.9 0.2 0.25 10.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain 3HCDH_N PF02737.18 EOO02280.1 - 9.2e-05 22.4 0.3 0.13 12.2 0.0 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EOO02280.1 - 0.00021 21.5 2.2 0.046 13.9 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EOO02280.1 - 0.00046 19.4 2.2 0.0032 16.6 0.7 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EOO02280.1 - 0.0011 18.1 0.5 0.11 11.5 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain UDPG_MGDP_dh_N PF03721.14 EOO02280.1 - 0.0034 17.0 0.1 0.42 10.1 0.0 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 EOO02280.1 - 0.0051 16.1 0.3 0.015 14.6 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EOO02280.1 - 0.042 13.2 0.3 0.43 9.9 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 EOO02280.1 - 0.061 12.6 0.1 0.19 11.0 0.0 1.9 1 1 1 2 2 2 0 Thi4 family XdhC_C PF13478.6 EOO02280.1 - 0.064 13.8 0.0 7.1 7.1 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain TrkA_N PF02254.18 EOO02280.1 - 0.13 12.6 0.6 19 5.6 0.2 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.6 EOO02280.1 - 0.17 12.3 0.1 6.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.24 EOO02280.1 - 0.31 10.6 3.0 16 5.0 0.3 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase MFAP1 PF06991.11 EOO02281.1 - 1.4e-73 247.3 37.8 1.4e-73 247.3 37.8 3.2 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing Ras PF00071.22 EOO02282.1 - 1.2e-52 177.8 0.0 1.4e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EOO02282.1 - 5.4e-19 68.6 0.0 7.4e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EOO02282.1 - 1.6e-06 27.7 0.0 2.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EOO02283.1 - 1.9e-07 31.1 1.7 6.8e-06 26.1 0.3 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EOO02283.1 - 0.00012 22.0 0.0 0.00044 20.2 0.0 1.9 1 1 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 EOO02283.1 - 0.00018 20.9 0.0 0.51 9.6 0.0 2.5 2 0 0 2 2 2 2 AIG1 family AAA_23 PF13476.6 EOO02283.1 - 0.0002 21.9 0.1 0.019 15.5 0.1 3.0 3 1 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 EOO02283.1 - 0.001 19.2 5.1 0.076 13.1 0.0 3.1 4 0 0 4 4 2 2 Dynamin family ABC_tran PF00005.27 EOO02283.1 - 0.0019 18.7 5.6 0.18 12.3 0.0 4.0 4 1 0 4 4 3 1 ABC transporter AAA_29 PF13555.6 EOO02283.1 - 0.003 17.2 0.0 0.0077 16.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.18 EOO02283.1 - 0.0042 16.4 0.2 0.017 14.4 0.2 2.0 1 1 0 1 1 1 1 Septin GTP_EFTU PF00009.27 EOO02283.1 - 0.0062 16.1 0.1 0.025 14.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 EOO02283.1 - 0.0086 15.2 0.0 0.022 13.8 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ATPase_2 PF01637.18 EOO02283.1 - 0.0086 16.0 5.1 0.46 10.4 0.0 3.5 4 0 0 4 4 3 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 EOO02283.1 - 0.0091 15.1 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Roc PF08477.13 EOO02283.1 - 0.011 15.9 0.0 0.24 11.6 0.0 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EOO02283.1 - 0.017 15.5 0.0 0.069 13.5 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EOO02283.1 - 0.017 15.4 0.1 0.45 10.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EOO02283.1 - 0.021 14.2 0.0 0.053 12.9 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Eaf7 PF07904.13 EOO02283.1 - 0.046 14.1 0.3 0.14 12.5 0.3 1.8 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 AAA_24 PF13479.6 EOO02283.1 - 0.049 13.4 1.2 0.16 11.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain Spore_IV_A PF09547.10 EOO02283.1 - 0.054 12.4 0.6 0.73 8.7 0.0 2.4 3 0 0 3 3 3 0 Stage IV sporulation protein A (spore_IV_A) AAA_7 PF12775.7 EOO02283.1 - 0.058 12.9 0.0 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_10 PF12846.7 EOO02283.1 - 0.061 12.2 0.1 0.17 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain TniB PF05621.11 EOO02283.1 - 0.063 12.7 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein SF3A3 PF16837.5 EOO02283.1 - 0.71 10.4 3.3 0.86 10.2 1.3 2.3 2 0 0 2 2 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 TBCC_N PF16752.5 EOO02283.1 - 1.3 9.5 10.3 0.46 10.9 0.3 3.7 4 0 0 4 4 3 0 Tubulin-specific chaperone C N-terminal domain tRNA-synt_2 PF00152.20 EOO02284.1 - 8.2e-88 294.5 0.0 1.1e-87 294.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EOO02284.1 - 8e-08 32.2 0.0 1.5e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 EOO02284.1 - 0.021 15.0 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain MDH PF02315.16 EOO02284.1 - 0.17 12.0 1.9 0.35 10.9 1.9 1.5 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit Phosphodiest PF01663.22 EOO02285.1 - 1.9e-14 54.1 0.2 3.9e-14 53.0 0.2 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EOO02285.1 - 0.00015 21.3 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EOO02285.1 - 0.00085 18.8 0.2 0.0014 18.0 0.2 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Neurensin PF14927.6 EOO02285.1 - 0.026 14.2 0.0 8 6.2 0.0 2.7 2 0 0 2 2 2 0 Neurensin DUF2976 PF11190.8 EOO02285.1 - 0.098 12.5 4.8 0.75 9.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) PglZ PF08665.12 EOO02285.1 - 0.15 12.1 0.4 19 5.3 0.1 2.4 2 0 0 2 2 2 0 PglZ domain DUF3445 PF11927.8 EOO02286.1 - 3.5e-67 226.3 0.0 4.2e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Ank_2 PF12796.7 EOO02287.1 - 2.5e-10 40.8 0.0 4.9e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EOO02287.1 - 2.3e-07 30.6 0.0 0.71 10.6 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EOO02287.1 - 2.8e-07 30.9 0.0 0.0036 17.8 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EOO02287.1 - 1e-06 28.9 0.9 0.00033 20.9 0.2 3.2 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EOO02287.1 - 3.5e-06 27.2 0.2 0.01 16.3 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat F-box-like PF12937.7 EOO02287.1 - 0.00095 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EOO02287.1 - 0.0034 17.2 0.0 0.0058 16.5 0.0 1.4 1 0 0 1 1 1 1 F-box domain Glyco_hydro_7 PF00840.20 EOO02288.1 - 7.1e-191 634.6 17.5 8e-191 634.4 17.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CytadhesinP1 PF12378.8 EOO02288.1 - 0.034 14.3 0.5 0.13 12.4 0.1 2.1 2 0 0 2 2 2 0 Trypsin-sensitive surface-exposed protein DUF5470 PF17564.2 EOO02288.1 - 0.43 10.8 3.3 0.66 10.2 0.8 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5470) MFS_1 PF07690.16 EOO02290.1 - 2.3e-27 95.9 32.8 2.3e-27 95.9 32.8 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Spp-24 PF07448.11 EOO02292.1 - 0.043 14.0 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain CVNH PF08881.10 EOO02294.1 - 8.5e-19 68.1 0.3 1e-18 67.9 0.3 1.1 1 0 0 1 1 1 1 CVNH domain Glyco_hydro_31 PF01055.26 EOO02295.1 - 1.1e-104 351.1 1.1 1.4e-104 350.8 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EOO02295.1 - 1e-14 54.6 0.3 4.4e-14 52.5 0.2 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like Cation_ATPase_C PF00689.21 EOO02296.1 - 1e-45 155.7 8.6 1e-45 155.7 8.6 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EOO02296.1 - 5.5e-20 71.2 0.0 1.1e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EOO02296.1 - 1.2e-18 68.2 0.3 1.2e-18 68.2 0.3 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EOO02296.1 - 4.8e-14 51.8 0.2 6.5e-13 48.2 0.2 2.6 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.20 EOO02296.1 - 5.3e-14 52.2 0.2 5.3e-14 52.2 0.2 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EOO02296.1 - 5e-05 23.2 0.3 0.00021 21.1 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EOO02296.1 - 0.035 14.5 0.0 0.072 13.5 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Gemini_mov PF01708.16 EOO02296.1 - 0.065 13.0 0.2 0.34 10.7 0.1 2.3 2 0 0 2 2 2 0 Geminivirus putative movement protein Pec_lyase_C PF00544.19 EOO02296.1 - 0.068 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Pectate lyase FliMN_C PF01052.20 EOO02296.1 - 0.095 12.7 0.0 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Type III flagellar switch regulator (C-ring) FliN C-term NDUF_B8 PF05821.11 EOO02297.1 - 6e-07 29.5 0.1 7.4e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) FAD_binding_4 PF01565.23 EOO02298.1 - 2.6e-20 72.6 3.8 5.6e-20 71.5 3.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EOO02298.1 - 0.11 12.7 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Berberine and berberine like AAA PF00004.29 EOO02299.1 - 2.9e-18 66.5 0.0 1.4e-17 64.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EOO02299.1 - 0.0078 16.6 0.0 0.054 13.9 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EOO02299.1 - 0.017 15.4 0.0 0.19 12.0 0.0 2.5 3 1 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 EOO02299.1 - 0.041 13.2 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 EOO02299.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 EOO02299.1 - 0.11 12.5 0.0 0.27 11.1 0.0 1.6 1 1 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 EOO02299.1 - 0.11 12.8 0.0 0.44 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EOO02299.1 - 0.18 12.2 0.0 2.8 8.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MFS_1 PF07690.16 EOO02300.1 - 5.4e-30 104.5 45.6 1.6e-29 103.0 23.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TetR_C_8 PF14278.6 EOO02300.1 - 0.024 14.7 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region SecE PF00584.20 EOO02300.1 - 0.4 10.6 0.1 0.4 10.6 0.1 3.2 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex p450 PF00067.22 EOO02301.1 - 1e-42 146.5 0.0 3.1e-21 75.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 YqgB PF11036.8 EOO02301.1 - 0.011 15.5 0.0 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Virulence promoting factor MFS_1 PF07690.16 EOO02302.1 - 1.8e-29 102.8 28.1 4.3e-29 101.5 28.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 EOO02303.1 - 5.7e-29 101.1 22.5 1.9e-27 96.2 21.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO02304.1 - 3.8e-93 312.8 23.1 4.3e-93 312.6 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO02304.1 - 2.1e-28 99.3 25.2 2.1e-28 99.3 25.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.15 EOO02304.1 - 0.43 10.5 3.6 1.4 8.8 3.6 1.9 1 0 0 1 1 1 0 Glycine zipper 2TM domain OATP PF03137.20 EOO02304.1 - 1.6 7.0 10.1 0.49 8.6 2.7 2.7 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2530 PF10745.9 EOO02304.1 - 2.5 8.4 6.6 2.7 8.3 1.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) PD40 PF07676.12 EOO02305.1 - 9.8e-17 60.4 0.3 1.2e-07 31.5 0.0 3.5 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 EOO02305.1 - 0.00075 18.3 0.0 0.041 12.6 0.0 2.8 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.11 EOO02305.1 - 0.0088 15.9 0.0 0.23 11.3 0.0 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A EF-hand_1 PF00036.32 EOO02306.1 - 6.3e-29 97.3 7.3 1.4e-09 36.8 0.0 3.1 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EOO02306.1 - 1.7e-22 79.7 5.7 3.5e-18 65.8 2.0 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EOO02306.1 - 7.2e-22 77.0 8.7 1.2e-11 44.3 0.9 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EOO02306.1 - 5.3e-21 73.1 3.6 5.9e-07 28.7 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EOO02306.1 - 6.2e-18 63.1 5.3 1.4e-08 33.9 0.1 3.1 3 0 0 3 3 3 3 EF-hand domain SPARC_Ca_bdg PF10591.9 EOO02306.1 - 2.8e-07 30.8 0.8 4.4e-06 27.0 0.2 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EOO02306.1 - 4.1e-06 26.7 3.2 0.0032 17.4 0.3 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EOO02306.1 - 2.9e-05 24.3 0.6 0.002 18.4 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 EOO02306.1 - 0.00027 21.8 0.1 0.00097 20.0 0.1 1.7 1 1 1 2 2 2 1 EF-hand domain Mst1_SARAH PF11629.8 EOO02306.1 - 0.0021 18.1 0.9 0.1 12.7 0.1 2.2 2 0 0 2 2 2 1 C terminal SARAH domain of Mst1 Dockerin_1 PF00404.18 EOO02306.1 - 0.0022 18.2 4.7 0.024 14.8 1.0 2.9 1 1 0 2 2 2 1 Dockerin type I domain TerB PF05099.13 EOO02306.1 - 0.0061 16.5 0.4 0.02 14.8 0.1 1.7 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF3349 PF11829.8 EOO02306.1 - 0.035 14.9 0.3 0.17 12.7 0.1 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3349) MotA_activ PF09114.10 EOO02306.1 - 0.1 12.8 0.1 0.17 12.0 0.1 1.5 1 1 1 2 2 2 0 Transcription factor MotA, activation domain Cu_amine_oxid PF01179.20 EOO02307.1 - 7e-127 423.7 7.7 8.6e-127 423.4 7.7 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 EOO02307.1 - 4.9e-37 125.5 0.9 1.1e-36 124.5 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 EOO02307.1 - 0.07 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain Aminotran_3 PF00202.21 EOO02308.1 - 6.9e-84 281.8 0.0 8.7e-84 281.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EOO02308.1 - 0.068 12.3 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II ComZ PF10815.8 EOO02308.1 - 0.085 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 ComZ Isochorismatase PF00857.20 EOO02309.1 - 2e-18 67.2 0.0 2.3e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family FAD_binding_2 PF00890.24 EOO02310.1 - 1.3e-91 307.8 0.0 1.4e-91 307.6 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EOO02310.1 - 7.1e-07 29.1 0.1 8e-05 22.4 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EOO02310.1 - 4.8e-06 26.7 0.0 1.9e-05 24.8 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EOO02310.1 - 1.4e-05 24.5 0.0 2.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EOO02310.1 - 0.00024 20.4 0.4 0.0014 17.9 0.1 2.3 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.22 EOO02310.1 - 0.00078 18.6 0.7 0.0012 18.0 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EOO02310.1 - 0.0061 15.8 0.9 0.018 14.3 0.1 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EOO02310.1 - 0.0067 15.2 3.7 0.075 11.7 0.1 2.7 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 EOO02310.1 - 0.013 14.9 0.0 0.031 13.6 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EOO02310.1 - 0.14 11.4 0.2 0.39 10.0 0.2 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 EOO02311.1 - 4.9e-13 48.7 40.2 2.4e-12 46.5 36.5 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EOO02311.1 - 2.1e-07 29.8 16.5 3e-07 29.3 16.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_M28 PF04389.17 EOO02312.1 - 5e-34 117.7 0.0 8.4e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EOO02312.1 - 4.9e-09 36.1 0.0 2.1e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EOO02312.1 - 6.4e-06 26.0 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 p450 PF00067.22 EOO02313.1 - 2.7e-70 237.4 0.0 3e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FANC_SAP PF18081.1 EOO02313.1 - 0.0089 16.2 0.0 0.72 10.1 0.0 3.3 3 0 0 3 3 3 1 Fanconi anemia-associated nuclease SAP domain Jiraiya PF15038.6 EOO02314.1 - 0.91 8.9 10.2 0.031 13.7 1.7 2.1 2 0 0 2 2 2 0 Jiraiya COX14 PF14880.6 EOO02314.1 - 1.1 9.1 0.0 1.1 9.1 0.0 2.5 3 0 0 3 3 3 0 Cytochrome oxidase c assembly DUF3959 PF13105.6 EOO02314.1 - 2.8 7.4 8.0 2.5 7.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) Aldo_ket_red PF00248.21 EOO02315.1 - 5.3e-34 117.7 0.0 5.9e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 EOO02316.1 - 6.1e-35 120.8 52.9 4.7e-34 117.9 52.7 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO02316.1 - 4.8e-13 48.8 10.1 4.8e-13 48.8 10.1 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EOO02316.1 - 5.7 5.1 20.2 0.094 11.0 3.5 2.7 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family 2-Hacid_dh_C PF02826.19 EOO02317.1 - 5e-56 188.9 0.0 6.6e-56 188.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EOO02317.1 - 1.3e-28 99.4 0.0 1.6e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EOO02317.1 - 0.0076 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EOO02317.1 - 0.012 15.7 0.1 0.042 13.9 0.1 1.8 1 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 EOO02317.1 - 0.036 13.4 0.1 0.7 9.1 0.1 2.2 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 EOO02317.1 - 0.075 12.6 0.0 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DpaA_N PF16924.5 EOO02317.1 - 0.13 12.3 0.0 6.4 6.9 0.0 2.3 1 1 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain DUF2205 PF10224.9 EOO02319.1 - 4.7e-36 122.6 0.8 7.1e-36 122.0 0.8 1.3 1 0 0 1 1 1 1 Short coiled-coil protein Glyco_hydro_11 PF00457.17 EOO02320.1 - 2.1e-81 271.8 21.6 2.4e-81 271.6 21.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 SNF2_N PF00176.23 EOO02321.1 - 3.9e-66 223.1 0.7 6.1e-66 222.5 0.7 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EOO02321.1 - 9.6e-19 67.8 0.0 4.5e-18 65.6 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO02321.1 - 5.3e-09 36.3 0.0 1.5e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 EOO02321.1 - 0.00037 20.8 6.9 0.0014 18.9 6.9 2.1 1 0 0 1 1 1 1 HSA HDA2-3 PF11496.8 EOO02321.1 - 0.0064 15.7 0.4 1.6 7.8 0.1 2.8 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 DUF4038 PF13204.6 EOO02323.1 - 6.4e-83 278.9 2.8 7.8e-83 278.6 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) MFS_1 PF07690.16 EOO02324.1 - 3.5e-08 32.8 18.3 4.2e-08 32.5 18.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.8 EOO02324.1 - 0.0032 16.2 4.1 0.0042 15.8 4.1 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like PI-PLC-C1 PF16670.5 EOO02325.1 - 6.7e-132 439.5 0.0 7.7e-132 439.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoinositide phospholipase C, Ca2+-dependent NAD_binding_2 PF03446.15 EOO02326.1 - 3.8e-30 105.2 0.6 6.1e-30 104.5 0.6 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EOO02326.1 - 1e-22 80.6 0.2 4.5e-22 78.6 0.0 2.0 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 EOO02326.1 - 3.6e-06 26.2 0.2 5.2e-06 25.6 0.2 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 EOO02326.1 - 0.0055 17.3 0.1 0.015 15.9 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1442 PF07279.11 EOO02326.1 - 0.11 11.9 0.1 0.6 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1442) DUF3094 PF11293.8 EOO02327.1 - 0.067 12.9 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) GFA PF04828.14 EOO02328.1 - 1e-17 64.2 0.9 1.6e-17 63.6 0.9 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF2197 PF09963.9 EOO02328.1 - 0.1 12.9 0.3 0.1 12.9 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Sugar_tr PF00083.24 EOO02329.1 - 2.6e-76 257.3 12.3 3.7e-75 253.5 12.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO02329.1 - 1.2e-14 54.1 20.0 7.5e-14 51.4 16.5 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Exo_endo_phos PF03372.23 EOO02330.1 - 3.5e-06 26.7 0.1 7.5e-06 25.6 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lactamase_B PF00753.27 EOO02331.1 - 2.4e-05 24.4 6.7 0.00015 21.8 6.7 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EOO02331.1 - 0.0001 21.9 0.2 0.00043 19.9 0.1 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain ADH_zinc_N PF00107.26 EOO02332.1 - 4e-20 72.1 0.0 5.6e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EOO02332.1 - 2e-17 63.1 0.0 3.5e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EOO02332.1 - 3.2e-08 34.7 0.0 5.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Polysacc_deac_1 PF01522.21 EOO02333.1 - 1.9e-27 95.6 0.0 2.7e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EOO02333.1 - 0.0052 16.0 0.0 0.0066 15.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Sulfatase PF00884.23 EOO02334.1 - 4.1e-46 157.8 0.0 5.3e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 EOO02334.1 - 0.002 16.8 0.0 0.0028 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 EOO02334.1 - 0.0034 17.6 0.2 0.009 16.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) DUF4994 PF16385.5 EOO02334.1 - 0.069 13.1 0.2 0.56 10.1 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function Sulfatase_C PF14707.6 EOO02334.1 - 0.11 13.2 0.4 1.4 9.6 0.1 2.4 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Sugar_tr PF00083.24 EOO02335.1 - 1.3e-115 386.8 20.9 2.1e-115 386.2 20.9 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO02335.1 - 1.9e-30 106.0 59.3 6.3e-25 87.8 28.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PALP PF00291.25 EOO02336.1 - 1.1e-78 264.6 0.4 1.4e-78 264.3 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EOO02336.1 - 1.2e-35 121.2 0.0 2.4e-20 72.1 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Fungal_trans_2 PF11951.8 EOO02337.1 - 1.9e-09 36.8 0.0 2.3e-09 36.6 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 EOO02340.1 - 6.7e-70 235.8 0.0 8.5e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EOO02340.1 - 3.2e-10 40.9 0.1 3.1e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain FKBP_C PF00254.28 EOO02341.1 - 1.8e-33 114.7 0.0 3.5e-33 113.8 0.0 1.5 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase PIG-S PF10510.9 EOO02342.1 - 6.4e-173 576.3 0.0 7.3e-173 576.1 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Pro_CA PF00484.19 EOO02343.1 - 1.3e-13 51.5 0.0 5.3e-13 49.5 0.0 2.0 1 1 0 1 1 1 1 Carbonic anhydrase SGL PF08450.12 EOO02343.1 - 0.00017 21.2 1.8 0.026 14.1 0.2 2.7 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 EOO02343.1 - 0.094 12.8 1.1 13 6.0 0.0 3.3 3 0 0 3 3 3 0 NHL repeat Polysacc_synt_4 PF04669.13 EOO02344.1 - 5.8e-24 84.7 1.4 2.7e-22 79.3 1.4 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis PIF6 PF05341.11 EOO02344.1 - 0.016 15.4 0.1 0.025 14.7 0.1 1.3 1 0 0 1 1 1 0 Per os infectivity factor 6 DUF2491 PF10679.9 EOO02344.1 - 0.033 13.4 1.0 0.039 13.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Peptidase_S9 PF00326.21 EOO02345.1 - 0.0015 18.1 0.1 0.039 13.4 0.0 2.6 3 0 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EOO02345.1 - 0.0063 15.8 0.0 0.17 11.1 0.0 2.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EOO02345.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EOO02345.1 - 0.26 10.9 1.6 4.9 6.7 0.6 3.0 2 2 0 2 2 2 0 alpha/beta hydrolase fold Transp_cyt_pur PF02133.15 EOO02346.1 - 7.2e-20 71.2 31.8 6.7e-18 64.7 31.4 2.9 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin RPN2_C PF18004.1 EOO02347.1 - 1.2e-57 194.3 2.8 1.2e-57 194.3 2.8 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EOO02347.1 - 8.8e-41 136.3 19.4 1.2e-08 35.0 0.0 8.1 7 0 0 7 7 7 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EOO02347.1 - 1.6e-20 73.3 0.0 2.4e-14 53.5 0.0 6.0 4 1 3 7 7 7 3 HEAT repeats HEAT PF02985.22 EOO02347.1 - 2.8e-06 27.1 0.5 1.2 9.6 0.0 6.0 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 EOO02347.1 - 3e-06 27.6 0.1 0.0024 18.3 0.0 4.7 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 EOO02347.1 - 0.015 15.4 0.2 2.1 8.4 0.0 3.1 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF3506 PF12014.8 EOO02348.1 - 6.7e-59 197.9 0.0 1.1e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 EOO02348.1 - 8.9e-09 35.1 2.0 1.7e-08 34.2 2.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EOO02348.1 - 2.8e-07 30.3 1.4 5.6e-07 29.3 1.4 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 EOO02348.1 - 0.012 16.1 0.0 0.026 15.1 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Myb_DNA-binding PF00249.31 EOO02349.1 - 3.3e-06 27.2 0.1 8.3e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EOO02349.1 - 0.0006 20.0 0.7 0.0011 19.1 0.3 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF1769 PF08588.10 EOO02350.1 - 3.2e-28 97.7 0.7 9.9e-28 96.1 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) Asparaginase PF00710.20 EOO02351.1 - 3.6e-26 91.9 0.0 5.6e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EOO02351.1 - 1.1e-12 48.2 0.0 1.9e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain PA PF02225.22 EOO02351.1 - 0.064 13.3 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 PA domain DnaJ-X PF14308.6 EOO02352.1 - 4.2e-77 258.3 2.2 4.2e-77 258.3 2.2 2.3 4 0 0 4 4 4 1 X-domain of DnaJ-containing DnaJ PF00226.31 EOO02352.1 - 3.2e-26 91.2 0.9 7.3e-26 90.1 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain LtuB PF17455.2 EOO02352.1 - 0.14 12.8 0.8 0.44 11.2 0.8 1.8 1 0 0 1 1 1 0 Late transcription unit B Aldose_epim PF01263.20 EOO02353.1 - 3.9e-44 151.2 0.1 5e-44 150.8 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase ADH_zinc_N_2 PF13602.6 EOO02354.1 - 6.6e-10 40.2 0.0 1.1e-09 39.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EOO02354.1 - 4.8e-06 26.6 0.3 1.6e-05 24.9 0.1 1.9 2 1 1 3 3 3 1 Zinc-binding dehydrogenase Acp26Ab PF05777.12 EOO02354.1 - 0.19 12.4 0.0 4.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) FAD_binding_2 PF00890.24 EOO02355.1 - 2.1e-54 185.2 1.0 2.5e-54 185.0 1.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EOO02355.1 - 2.8e-10 40.3 1.8 4.5e-09 36.3 1.8 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EOO02355.1 - 1.4e-07 31.6 0.9 1.4e-07 31.6 0.9 2.2 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EOO02355.1 - 5e-07 29.4 0.9 8.9e-07 28.6 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EOO02355.1 - 7.5e-07 28.6 6.3 9.1e-05 21.7 2.4 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EOO02355.1 - 0.00011 21.5 3.3 0.0014 17.9 0.8 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EOO02355.1 - 0.00034 19.5 8.6 0.00043 19.1 0.8 2.8 4 0 0 4 4 4 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EOO02355.1 - 0.00036 19.9 0.3 0.00064 19.1 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EOO02355.1 - 0.00048 19.5 0.8 0.00076 18.8 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EOO02355.1 - 0.0012 18.1 0.9 0.0038 16.5 0.6 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 EOO02355.1 - 0.0019 18.7 0.5 0.013 16.1 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Tail_VII PF17091.5 EOO02355.1 - 0.039 13.8 0.8 0.14 12.1 0.8 2.0 1 0 0 1 1 1 0 Inovirus G7P protein Lycopene_cycl PF05834.12 EOO02355.1 - 0.049 12.7 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EOO02355.1 - 0.072 12.3 0.3 0.16 11.2 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_S5 PF00333.20 EOO02356.1 - 4.2e-25 87.5 1.0 1.1e-24 86.2 1.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EOO02356.1 - 5.9e-23 80.1 0.0 1e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 EOO02356.1 - 6.8 7.3 16.5 16 6.1 16.5 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 AhpC-TSA PF00578.21 EOO02357.1 - 7.5e-29 100.2 0.0 9.9e-29 99.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EOO02357.1 - 5.9e-11 42.3 0.0 8e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EOO02357.1 - 7.1e-11 41.8 0.1 1.4e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EOO02357.1 - 0.053 13.4 0.0 0.092 12.7 0.0 1.6 1 1 0 1 1 1 0 SCO1/SenC F-box-like PF12937.7 EOO02359.1 - 5.1e-05 23.1 0.1 0.00084 19.2 0.0 3.0 3 1 0 3 3 3 1 F-box-like DUF4267 PF14087.6 EOO02360.1 - 4e-15 55.8 0.8 5.3e-15 55.5 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) NIBRIN_BRCT_II PF16508.5 EOO02361.1 - 1.6e-39 134.9 0.0 5.9e-39 133.1 0.0 2.0 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 EOO02361.1 - 1.7e-10 41.1 0.2 3.4e-10 40.1 0.2 1.5 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 EOO02361.1 - 9.7e-05 22.2 0.0 0.00025 20.9 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 EOO02361.1 - 0.00058 20.2 0.6 0.019 15.3 0.2 3.0 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Yop-YscD_cpl PF16697.5 EOO02361.1 - 0.086 13.2 0.8 0.86 10.0 0.3 2.7 2 1 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain Nbs1_C PF08599.10 EOO02361.1 - 9.3 6.5 9.3 0.46 10.7 0.8 3.1 3 0 0 3 3 3 0 DNA damage repair protein Nbs1 Acetyltransf_1 PF00583.25 EOO02362.1 - 9.9e-11 41.9 0.0 1.4e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EOO02362.1 - 2.3e-07 30.8 0.0 3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EOO02362.1 - 2.2e-05 24.8 0.0 3.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EOO02362.1 - 0.00011 22.9 0.0 0.00014 22.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EOO02362.1 - 0.17 11.9 0.0 0.54 10.3 0.0 1.8 1 1 0 1 1 1 0 FR47-like protein Memo PF01875.17 EOO02363.1 - 6.2e-72 242.0 0.0 7.2e-72 241.8 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein gpUL132 PF11359.8 EOO02363.1 - 0.12 12.0 0.0 0.28 10.7 0.0 1.7 1 1 0 1 1 1 0 Glycoprotein UL132 IMS PF00817.20 EOO02364.1 - 3.2e-43 147.3 0.2 5.7e-43 146.5 0.2 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EOO02364.1 - 5.5e-17 62.5 0.0 1.4e-16 61.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EOO02364.1 - 1.7e-05 24.9 0.0 4e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Arg_repressor PF01316.21 EOO02364.1 - 0.19 11.5 0.7 0.41 10.4 0.7 1.5 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Cupin_2 PF07883.11 EOO02365.1 - 3.3e-11 42.7 0.1 4.3e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EOO02365.1 - 0.00035 20.2 0.0 0.00038 20.1 0.0 1.0 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 EOO02365.1 - 0.0041 16.8 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Auxin_BP PF02041.16 EOO02365.1 - 0.0099 15.6 0.0 0.012 15.3 0.0 1.0 1 0 0 1 1 1 1 Auxin binding protein MFS_1 PF07690.16 EOO02366.1 - 1.4e-32 113.0 27.6 1.4e-32 113.0 27.6 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TMPIT PF07851.13 EOO02366.1 - 0.77 8.9 3.1 1.6 7.9 3.1 1.4 1 0 0 1 1 1 0 TMPIT-like protein TLD PF07534.16 EOO02367.1 - 8.8e-28 97.3 0.0 1.6e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 TLD DUF1773 PF08593.10 EOO02367.1 - 2.6e-17 63.6 1.0 7.7e-17 62.1 1.0 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF3176 PF11374.8 EOO02368.1 - 0.17 12.1 1.5 0.43 10.8 0.1 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3176) Peptidase_S8 PF00082.22 EOO02369.1 - 1.9e-29 102.9 17.0 3.8e-29 101.9 17.0 1.4 1 0 0 1 1 1 1 Subtilase family COesterase PF00135.28 EOO02370.1 - 2.4e-37 129.0 0.0 3.7e-19 69.0 0.0 2.2 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EOO02370.1 - 0.05 13.4 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold NmrA PF05368.13 EOO02371.1 - 7.6e-26 91.1 0.5 9.6e-26 90.8 0.5 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO02371.1 - 8e-21 74.8 0.0 1.3e-20 74.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EOO02371.1 - 8.9e-07 29.2 0.4 9.7e-06 25.9 0.1 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EOO02371.1 - 2.5e-06 27.2 0.1 7.2e-06 25.6 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EOO02371.1 - 6e-06 26.4 0.1 1e-05 25.6 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 EOO02371.1 - 0.0035 16.8 0.2 0.007 15.8 0.2 1.6 1 1 1 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.19 EOO02371.1 - 0.0064 15.5 0.1 0.012 14.7 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.6 EOO02371.1 - 0.0081 16.6 0.1 0.018 15.5 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 EOO02371.1 - 0.016 15.5 0.1 0.036 14.3 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain DFP PF04127.15 EOO02371.1 - 0.029 14.2 0.3 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein GDP_Man_Dehyd PF16363.5 EOO02371.1 - 0.034 13.5 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 EOO02371.1 - 0.08 13.4 0.5 0.17 12.3 0.2 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_trans_4_2 PF13477.6 EOO02371.1 - 0.11 12.6 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase 4-like HgmA PF04209.13 EOO02373.1 - 5.6e-105 351.5 0.1 6.4e-105 351.3 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase UbiA PF01040.18 EOO02374.1 - 8.1e-47 159.6 15.9 1e-46 159.3 15.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Pyr_redox_2 PF07992.14 EOO02375.1 - 1.4e-26 93.4 0.2 5e-26 91.6 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EOO02375.1 - 1e-15 58.0 0.5 1.9e-13 50.8 0.3 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EOO02375.1 - 0.0003 20.1 0.1 0.00065 19.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EOO02375.1 - 0.00038 19.7 0.0 0.0008 18.6 0.0 1.4 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EOO02375.1 - 0.0016 17.3 0.4 0.84 8.3 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein Trp_halogenase PF04820.14 EOO02375.1 - 0.002 17.1 0.4 1.2 7.9 0.2 2.2 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 EOO02375.1 - 0.0021 17.7 1.6 0.16 11.5 0.1 3.5 4 0 0 4 4 4 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EOO02375.1 - 0.0041 16.2 0.0 0.0062 15.6 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DNA_processg_A PF02481.15 EOO02375.1 - 0.0058 15.9 0.1 1.4 8.1 0.0 2.3 2 0 0 2 2 2 2 DNA recombination-mediator protein A NAD_binding_9 PF13454.6 EOO02375.1 - 0.0061 16.6 4.6 2.3 8.2 0.1 3.4 2 1 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 EOO02375.1 - 0.029 13.6 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GnsAB_toxin PF08178.11 EOO02375.1 - 0.04 13.8 0.1 0.077 12.9 0.1 1.4 1 0 0 1 1 1 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system GIDA PF01134.22 EOO02375.1 - 0.046 12.8 0.6 1 8.4 0.1 2.7 2 1 0 3 3 3 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EOO02375.1 - 0.1 11.8 0.1 0.1 11.8 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Mqo PF06039.15 EOO02375.1 - 0.24 9.9 0.4 0.55 8.7 0.1 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.6 EOO02375.1 - 0.89 9.8 3.3 2 8.7 0.0 2.9 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EOO02375.1 - 4 6.7 8.3 1.4 8.2 0.1 2.8 2 1 0 3 3 3 0 FAD dependent oxidoreductase AMP-binding PF00501.28 EOO02376.1 - 9.9e-31 106.8 0.1 1.2e-30 106.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EOO02376.1 - 8e-13 49.2 0.0 1.4e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_8 PF13523.6 EOO02377.1 - 3.4e-45 153.3 0.6 4.8e-45 152.8 0.6 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EOO02377.1 - 0.049 14.3 0.1 0.1 13.3 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Transp_cyt_pur PF02133.15 EOO02378.1 - 9.8e-90 301.4 34.9 1.2e-89 301.2 34.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ABC_tran PF00005.27 EOO02379.1 - 6.2e-31 107.7 0.0 9.8e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EOO02379.1 - 2.9e-11 43.6 3.9 4.1e-11 43.1 3.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 EOO02379.1 - 7.4e-08 32.5 0.2 0.0019 18.0 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EOO02379.1 - 4.5e-05 23.0 0.0 0.021 14.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EOO02379.1 - 0.00028 20.6 0.0 0.00077 19.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 EOO02379.1 - 0.00038 20.6 0.0 0.00063 19.9 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_16 PF13191.6 EOO02379.1 - 0.0043 17.4 0.2 0.089 13.2 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EOO02379.1 - 0.0089 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 EOO02379.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EOO02379.1 - 0.012 15.9 0.0 0.098 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EOO02379.1 - 0.025 14.2 0.5 1.7 8.2 0.2 2.4 1 1 1 2 2 2 0 AAA domain DEAD PF00270.29 EOO02379.1 - 0.18 11.6 0.0 0.49 10.2 0.0 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF5325 PF17259.2 EOO02379.1 - 0.44 10.5 2.1 1 9.3 1.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5325) TrkH PF02386.16 EOO02380.1 - 7.9e-53 179.6 5.5 2.3e-49 168.2 0.1 2.0 2 0 0 2 2 2 2 Cation transport protein DUF3336 PF11815.8 EOO02381.1 - 8e-29 100.1 0.0 1.5e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EOO02381.1 - 3.1e-21 76.5 0.0 6.9e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase DUF463 PF04317.12 EOO02382.1 - 0.078 11.9 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 AXE1 PF05448.12 EOO02382.1 - 0.24 10.0 0.1 0.4 9.3 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Translin PF01997.16 EOO02383.1 - 2.5e-51 174.6 0.0 3e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Translin family SQS_PSY PF00494.19 EOO02384.1 - 4.2e-36 124.8 0.0 7.1e-36 124.1 0.0 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase PDGLE PF13190.6 EOO02384.1 - 0.17 11.8 0.1 5 7.1 0.0 2.2 2 0 0 2 2 2 0 PDGLE domain RPEL PF02755.15 EOO02385.1 - 1.3e-16 59.7 6.1 1.6e-08 33.9 0.0 3.1 3 0 0 3 3 3 2 RPEL repeat HIG_1_N PF04588.13 EOO02387.1 - 4.3e-23 81.3 2.5 6.6e-23 80.7 2.5 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region CSRNP_N PF16019.5 EOO02387.1 - 0.1 12.5 1.2 0.13 12.1 1.2 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus AAA_11 PF13086.6 EOO02387.1 - 0.16 11.7 2.6 0.2 11.4 2.6 1.1 1 0 0 1 1 1 0 AAA domain DUF1168 PF06658.12 EOO02387.1 - 0.45 10.3 12.7 0.9 9.3 12.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Cyt-b5 PF00173.28 EOO02388.1 - 2.4e-15 56.4 0.0 3.3e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RmlD_sub_bind PF04321.17 EOO02389.1 - 9.1e-13 47.9 0.0 1.3e-12 47.4 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EOO02389.1 - 1.7e-10 40.8 0.0 3.3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EOO02389.1 - 0.00047 19.4 0.0 0.0007 18.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EOO02389.1 - 0.026 13.9 0.0 0.06 12.7 0.0 1.6 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EOO02389.1 - 0.12 11.4 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Rhodanese PF00581.20 EOO02390.1 - 1e-17 64.6 0.0 2.6e-10 40.8 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain TAF4 PF05236.14 EOO02391.1 - 0.037 13.8 19.2 0.052 13.3 18.1 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family DDHD PF02862.17 EOO02391.1 - 0.049 13.8 9.8 0.12 12.5 9.8 1.7 1 0 0 1 1 1 0 DDHD domain DUF2151 PF10221.9 EOO02391.1 - 0.28 9.7 16.4 0.42 9.1 16.4 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator CobT PF06213.12 EOO02391.1 - 0.49 9.7 28.7 1 8.7 28.7 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PTPRCAP PF15713.5 EOO02391.1 - 0.56 10.5 23.5 2.1 8.6 23.5 2.0 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RP-C_C PF11800.8 EOO02391.1 - 0.66 10.0 18.9 1.6 8.8 18.9 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region RAP1 PF07218.11 EOO02391.1 - 0.77 8.0 12.5 1.5 7.0 12.5 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2828 PF11443.8 EOO02391.1 - 1.4 6.9 16.8 2.1 6.3 16.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Paf1 PF03985.13 EOO02391.1 - 1.5 7.8 31.2 2.4 7.1 31.2 1.3 1 0 0 1 1 1 0 Paf1 DDRGK PF09756.9 EOO02391.1 - 4.1 7.0 44.1 91 2.6 43.3 2.5 2 0 0 2 2 2 0 DDRGK domain Zip PF02535.22 EOO02391.1 - 4.1 6.5 15.9 7.3 5.7 15.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2052 PF09747.9 EOO02391.1 - 4.2 7.5 28.3 16 5.5 28.3 2.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF913 PF06025.12 EOO02391.1 - 4.2 6.2 13.7 8.2 5.3 13.7 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AAA_11 PF13086.6 EOO02391.1 - 4.7 6.9 19.4 61 3.3 21.6 1.7 2 0 0 2 2 2 0 AAA domain Borrelia_P83 PF05262.11 EOO02391.1 - 5.9 5.3 29.7 13 4.2 29.7 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein GREB1 PF15782.5 EOO02391.1 - 7 3.6 12.9 10 3.1 12.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 EOO02391.1 - 7.4 5.2 24.9 12 4.5 24.9 1.2 1 0 0 1 1 1 0 Presenilin Gpr1_Fun34_YaaH PF01184.19 EOO02392.1 - 2.8e-91 304.8 21.4 3.5e-91 304.4 21.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family mRNA_triPase PF02940.15 EOO02393.1 - 9.3e-37 126.9 0.7 1.1e-36 126.6 0.7 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain FAD_binding_3 PF01494.19 EOO02394.1 - 0.00053 19.3 0.1 0.0011 18.3 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Tannase PF07519.11 EOO02395.1 - 1.3e-52 179.3 0.2 2.4e-52 178.4 0.2 1.4 1 1 0 1 1 1 1 Tannase and feruloyl esterase PAH PF02671.21 EOO02395.1 - 0.029 14.5 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 Paired amphipathic helix repeat Syntaxin PF00804.25 EOO02396.1 - 5.1e-17 62.2 12.9 5.1e-17 62.2 12.9 2.2 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.19 EOO02396.1 - 6.5e-12 45.3 1.7 6.5e-12 45.3 1.7 2.8 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 EOO02396.1 - 0.00013 22.3 5.2 0.00013 22.3 5.2 2.4 2 0 0 2 2 2 1 Syntaxin-like protein DUF5305 PF17231.2 EOO02396.1 - 0.0063 16.0 0.6 0.011 15.2 0.6 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Orf78 PF06024.12 EOO02396.1 - 0.015 15.6 3.1 0.016 15.5 1.4 1.9 1 1 0 2 2 2 0 Orf78 (ac78) EphA2_TM PF14575.6 EOO02396.1 - 0.019 15.9 0.1 0.059 14.3 0.1 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ETRAMP PF09716.10 EOO02396.1 - 0.03 14.4 0.1 0.086 12.9 0.0 1.9 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Sigma_reg_N PF13800.6 EOO02396.1 - 0.051 13.9 0.7 0.1 12.9 0.7 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal 7tm_7 PF08395.12 EOO02396.1 - 0.15 11.3 4.4 0.27 10.4 0.0 2.7 3 0 0 3 3 3 0 7tm Chemosensory receptor UL42 PF17638.2 EOO02396.1 - 0.15 12.0 0.6 0.33 10.9 0.6 1.5 1 0 0 1 1 1 0 HCMV UL42 DUF2116 PF09889.9 EOO02396.1 - 0.23 11.5 2.0 0.69 9.9 2.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Insulin_TMD PF17870.1 EOO02396.1 - 0.52 10.4 6.1 0.97 9.5 6.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Mod_r PF07200.13 EOO02396.1 - 0.54 10.3 14.5 1 9.4 3.6 3.1 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein V-SNARE PF05008.15 EOO02396.1 - 0.65 10.4 15.8 0.64 10.4 1.8 3.9 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus BLOC1_2 PF10046.9 EOO02396.1 - 2.5 8.4 8.0 10 6.5 1.2 3.4 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RIFIN PF02009.16 EOO02396.1 - 4.3 7.1 12.6 8.3 6.2 12.0 1.7 1 1 0 1 1 1 0 Rifin Oxidored_molyb PF00174.19 EOO02397.1 - 8.1e-58 194.8 0.0 1.2e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EOO02397.1 - 6.5e-27 94.2 0.1 1.7e-26 92.9 0.1 1.7 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 EOO02397.1 - 1.1e-12 47.9 0.1 1.9e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.20 EOO02397.1 - 0.71 10.1 2.4 0.97 9.7 0.3 2.5 2 0 0 2 2 2 0 BNR/Asp-box repeat Jiv90 PF14901.6 EOO02397.1 - 2 8.6 6.7 3.7 7.8 0.0 3.6 3 1 1 4 4 4 0 Cleavage inducing molecular chaperone Abhydrolase_1 PF00561.20 EOO02398.1 - 5e-05 23.1 0.1 0.00012 21.8 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 EOO02398.1 - 0.032 14.1 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_8 PF06259.12 EOO02398.1 - 0.15 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF900 PF05990.12 EOO02398.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 EOO02399.1 - 1.1e-09 39.2 9.4 1.4e-09 38.9 9.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EOO02399.1 - 1.9e-09 37.6 0.0 2.4e-08 34.0 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EOO02399.1 - 0.024 14.8 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein DUF1057 PF06342.12 EOO02399.1 - 0.073 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_S9 PF00326.21 EOO02399.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family cIII PF08134.11 EOO02399.1 - 0.13 12.1 0.3 0.26 11.1 0.3 1.5 1 0 0 1 1 1 0 cIII protein family TAL_FSA PF00923.19 EOO02401.1 - 2.5e-34 119.0 0.0 3.1e-34 118.6 0.0 1.3 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase SSF PF00474.17 EOO02402.1 - 3.3e-21 75.6 28.3 5.9e-21 74.8 28.3 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family GFO_IDH_MocA PF01408.22 EOO02403.1 - 1.5e-16 61.3 0.0 4.5e-14 53.3 0.0 2.2 2 0 0 2 2 2 2 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EOO02403.1 - 6.9e-08 32.5 0.0 2.4e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain MFS_1 PF07690.16 EOO02404.1 - 1.4e-12 47.2 29.4 6.6e-08 31.9 1.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO02404.1 - 2e-08 33.6 20.2 7.2e-07 28.4 20.1 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter Ribonuc_L-PSP PF01042.21 EOO02405.1 - 3.6e-12 46.3 0.0 5.1e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP NUDE_C PF04880.13 EOO02405.1 - 0.18 12.2 0.4 0.23 11.9 0.4 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region p450 PF00067.22 EOO02406.1 - 1.6e-33 116.2 0.7 2.2e-19 69.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Host_attach PF10116.9 EOO02406.1 - 0.097 13.2 0.0 0.23 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein required for attachment to host cells SKI PF01202.22 EOO02407.1 - 3.6e-12 46.7 0.0 4.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 EOO02407.1 - 9.5e-11 42.0 0.0 1.3e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EOO02407.1 - 3.4e-09 37.3 0.0 9.9e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 EOO02407.1 - 4.4e-06 26.7 0.2 0.0052 16.7 0.0 2.2 1 1 0 2 2 2 2 Deoxynucleoside kinase Cytidylate_kin PF02224.18 EOO02407.1 - 6.7e-05 22.7 0.0 9.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase Rad17 PF03215.15 EOO02407.1 - 0.00018 21.5 0.1 0.00079 19.4 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 EOO02407.1 - 0.00019 21.7 0.0 0.0004 20.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EOO02407.1 - 0.00083 19.8 0.0 0.0034 17.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EOO02407.1 - 0.0013 19.2 0.3 0.0022 18.4 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 EOO02407.1 - 0.0013 18.7 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase T2SSE PF00437.20 EOO02407.1 - 0.0022 17.1 0.3 0.004 16.2 0.3 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein NACHT PF05729.12 EOO02407.1 - 0.003 17.5 0.0 0.0078 16.2 0.0 1.7 2 0 0 2 2 1 1 NACHT domain AAA PF00004.29 EOO02407.1 - 0.0039 17.6 0.4 0.0083 16.6 0.4 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EOO02407.1 - 0.0062 15.8 0.3 0.017 14.4 0.3 2.0 1 1 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.22 EOO02407.1 - 0.0084 16.5 0.0 0.015 15.6 0.0 1.5 1 1 0 1 1 1 1 RNA helicase DUF2075 PF09848.9 EOO02407.1 - 0.012 14.9 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 EOO02407.1 - 0.02 14.6 0.1 0.025 14.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EOO02407.1 - 0.039 13.7 0.5 0.075 12.7 0.1 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EOO02407.1 - 0.04 14.4 0.0 0.062 13.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter ADK PF00406.22 EOO02407.1 - 0.042 14.0 0.3 6.3 6.9 0.1 2.1 2 0 0 2 2 2 0 Adenylate kinase AAA_14 PF13173.6 EOO02407.1 - 0.062 13.3 0.3 0.44 10.6 0.0 2.2 2 1 1 3 3 3 0 AAA domain Thymidylate_kin PF02223.17 EOO02407.1 - 0.073 12.7 0.0 6.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_11 PF13086.6 EOO02407.1 - 0.079 12.7 0.1 0.12 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain CoaE PF01121.20 EOO02407.1 - 0.096 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase PhoH PF02562.16 EOO02407.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RuvB_N PF05496.12 EOO02407.1 - 0.11 12.3 0.1 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 EOO02407.1 - 0.12 12.7 1.4 0.37 11.1 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EOO02407.1 - 0.12 12.6 0.6 0.27 11.5 0.1 1.7 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 EOO02407.1 - 0.14 11.7 1.4 0.37 10.4 1.4 2.0 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 EOO02407.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 EOO02407.1 - 0.15 12.0 0.6 0.82 9.6 0.0 2.0 2 1 0 2 2 2 0 NTPase FAD_binding_3 PF01494.19 EOO02408.1 - 1.4e-12 47.5 0.1 4.7e-05 22.8 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EOO02408.1 - 7e-07 28.8 0.0 0.0062 15.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EOO02408.1 - 6.7e-05 22.6 0.0 8.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EOO02408.1 - 0.00015 22.0 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EOO02408.1 - 0.00037 21.0 0.2 0.42 11.2 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EOO02408.1 - 0.0026 16.9 0.2 0.0099 15.0 0.2 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EOO02408.1 - 0.0033 16.7 0.0 0.045 13.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EOO02408.1 - 0.011 14.9 0.2 0.099 11.7 0.1 2.1 1 1 1 2 2 2 0 FAD binding domain Thi4 PF01946.17 EOO02408.1 - 0.086 12.1 0.2 0.19 10.9 0.0 1.5 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 EOO02408.1 - 0.18 10.8 0.0 6.2 5.8 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Fungal_trans PF04082.18 EOO02409.1 - 1.2e-18 67.2 0.3 2.4e-18 66.1 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EOO02409.1 - 1.9e-05 24.7 15.0 3.4e-05 23.9 15.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 EOO02410.1 - 1.7e-23 82.6 3.5 2.8e-23 81.9 3.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EOO02410.1 - 2.4e-17 63.2 0.1 8.9e-17 61.3 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EOO02410.1 - 1.3e-16 60.7 0.0 9.3e-16 57.9 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO02410.1 - 7.6e-13 48.5 0.0 2.1e-12 47.1 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N_2 PF13602.6 EOO02410.1 - 3.8e-06 28.0 0.0 1.1e-05 26.5 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EOO02410.1 - 0.0047 16.3 0.1 0.01 15.1 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EOO02410.1 - 0.0081 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ABC2_membrane PF01061.24 EOO02411.1 - 7.7e-73 244.4 45.5 8.5e-37 126.6 17.2 3.5 2 1 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EOO02411.1 - 1.1e-43 149.0 0.0 2.4e-23 83.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EOO02411.1 - 1.6e-26 92.1 0.8 8.9e-24 83.2 0.1 3.1 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 EOO02411.1 - 5.3e-08 32.4 25.7 1.6e-06 27.5 4.1 3.1 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 EOO02411.1 - 7e-07 29.8 0.1 0.00049 20.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EOO02411.1 - 6.5e-05 23.2 0.2 0.36 11.1 0.1 3.1 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EOO02411.1 - 6.9e-05 22.8 0.8 0.0007 19.5 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 EOO02411.1 - 0.00016 21.2 0.0 0.26 10.7 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EOO02411.1 - 0.00021 21.2 0.3 0.16 11.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EOO02411.1 - 0.0016 18.9 0.4 8.8 6.8 0.0 4.0 5 0 0 5 5 4 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EOO02411.1 - 0.0026 17.5 0.4 0.049 13.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EOO02411.1 - 0.005 16.6 0.1 0.54 9.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EOO02411.1 - 0.0094 15.9 0.8 0.48 10.3 0.1 2.8 3 0 0 3 3 3 1 NACHT domain AAA_19 PF13245.6 EOO02411.1 - 0.019 15.3 0.9 4.6 7.6 0.0 3.4 4 0 0 4 4 4 0 AAA domain MMR_HSR1 PF01926.23 EOO02411.1 - 0.027 14.5 0.4 3.9 7.6 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.6 EOO02411.1 - 0.03 13.9 0.1 0.091 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EOO02411.1 - 0.04 14.2 0.0 0.46 10.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EOO02411.1 - 0.043 13.8 0.2 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 EOO02411.1 - 0.044 13.4 0.1 1 8.9 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EOO02411.1 - 0.047 13.9 0.3 1.8 8.8 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 EOO02411.1 - 0.058 14.0 0.0 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EOO02411.1 - 0.078 12.7 0.0 1.8 8.3 0.1 2.6 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 EOO02411.1 - 0.12 11.7 0.0 5.3 6.3 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ATPase_2 PF01637.18 EOO02411.1 - 0.15 11.9 0.0 17 5.2 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EOO02411.1 - 0.18 10.9 0.6 4.4 6.4 0.2 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 EOO02411.1 - 0.2 11.8 0.2 0.76 9.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EOO02411.1 - 0.21 11.3 0.2 19 5.0 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain FKS1_dom1 PF14288.6 EOO02412.1 - 7.7e-41 139.4 5.1 1.6e-40 138.4 3.1 2.5 2 1 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Ac76 PF05814.11 EOO02412.1 - 0.4 10.7 2.6 2 8.5 0.1 2.6 2 0 0 2 2 2 0 Orf76 (Ac76) Cupin_2 PF07883.11 EOO02413.1 - 5.9e-16 57.9 0.1 1.4e-11 43.9 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 EOO02413.1 - 0.00041 20.3 2.6 0.0075 16.2 0.7 2.8 2 1 1 3 3 3 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EOO02413.1 - 0.029 14.0 0.0 1.4 8.6 0.0 2.7 2 1 1 3 3 3 0 Cupin DUF1992 PF09350.10 EOO02413.1 - 0.2 11.8 0.1 1.1 9.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1992) Fungal_trans PF04082.18 EOO02414.1 - 6.2e-14 51.7 0.1 9.8e-14 51.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EOO02414.1 - 1.7e-08 34.4 9.4 3.1e-08 33.6 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G_glu_transpept PF01019.21 EOO02415.1 - 3.9e-133 444.9 0.1 4.5e-133 444.7 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase FMO-like PF00743.19 EOO02416.1 - 1.3e-21 76.7 0.0 2.7e-16 59.1 0.1 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EOO02416.1 - 4.1e-20 72.2 0.0 1.4e-18 67.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EOO02416.1 - 6.8e-12 45.2 0.0 1.6e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EOO02416.1 - 1.4e-08 34.3 0.0 9.4e-07 28.3 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EOO02416.1 - 4.4e-05 23.6 0.1 0.047 13.9 0.0 2.8 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 EOO02416.1 - 0.00014 21.3 0.0 0.035 13.5 0.0 2.6 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EOO02416.1 - 0.00028 21.4 0.4 6.4 7.4 0.2 3.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EOO02416.1 - 0.0007 19.0 0.2 0.4 10.0 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EOO02416.1 - 0.0011 18.3 0.4 0.99 8.6 0.3 3.0 4 0 0 4 4 4 2 FAD binding domain HI0933_like PF03486.14 EOO02416.1 - 0.0049 15.6 0.1 0.47 9.1 0.2 2.4 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EOO02416.1 - 0.0062 15.8 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 EOO02416.1 - 0.0082 15.3 0.8 0.42 9.6 0.0 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.24 EOO02416.1 - 0.0084 15.7 0.2 17 4.8 0.2 3.6 3 1 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EOO02416.1 - 0.012 14.7 0.0 0.048 12.7 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EOO02416.1 - 0.03 14.3 2.5 0.73 9.8 0.1 3.2 3 1 1 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EOO02416.1 - 0.085 11.9 0.4 2.6 7.0 1.4 2.6 3 0 0 3 3 3 0 FAD binding domain NmrA PF05368.13 EOO02418.1 - 3.4e-33 115.1 0.0 5.8e-33 114.4 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO02418.1 - 5.6e-14 52.5 0.0 9.9e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EOO02418.1 - 2.6e-06 27.1 0.0 3.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO02418.1 - 0.0025 17.3 0.0 0.0038 16.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EOO02418.1 - 0.023 13.7 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 EOO02418.1 - 0.024 14.9 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain OTCace PF00185.24 EOO02418.1 - 0.15 12.1 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Ribosomal_S11 PF00411.19 EOO02420.1 - 1.5e-09 38.2 0.0 2.1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Phage_Mu_Gam PF07352.12 EOO02420.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Mito_carr PF00153.27 EOO02421.1 - 2e-58 194.3 0.0 4.7e-19 68.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FKBP_C PF00254.28 EOO02422.1 - 4e-32 110.4 0.0 1.6e-31 108.5 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EOO02422.1 - 3e-28 98.4 6.6 3e-28 98.4 6.6 2.5 2 2 0 2 2 2 1 Nucleoplasmin-like domain Utp14 PF04615.13 EOO02422.1 - 0.051 12.1 39.8 0.071 11.7 39.8 1.1 1 0 0 1 1 1 0 Utp14 protein MFS_1 PF07690.16 EOO02423.1 - 1e-52 179.2 36.2 1e-52 179.2 36.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO02423.1 - 4.6e-13 48.8 14.3 4.6e-13 48.8 14.3 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EOO02423.1 - 6.2e-08 31.5 0.5 9.4e-08 30.9 0.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cpn60_TCP1 PF00118.24 EOO02424.1 - 3.4e-150 500.9 15.2 3.8e-150 500.7 15.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2263 PF10021.9 EOO02425.1 - 1.7e-22 80.4 0.0 3.2e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Glyco_trans_2_3 PF13632.6 EOO02426.1 - 1.9e-14 54.0 0.1 3.2e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 ATG11 PF10377.9 EOO02427.1 - 1.6e-46 157.6 0.1 4.6e-46 156.1 0.0 1.8 2 0 0 2 2 2 1 Autophagy-related protein 11 WD40 PF00400.32 EOO02428.1 - 3.4e-42 141.6 19.1 2.7e-09 37.5 0.3 6.5 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO02428.1 - 1.7e-18 66.7 0.0 0.00093 19.5 0.0 5.2 3 1 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EOO02428.1 - 1.2e-05 24.4 0.4 0.44 9.4 0.0 4.1 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EOO02428.1 - 1.8e-05 24.2 0.0 0.046 13.1 0.0 2.1 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 EOO02428.1 - 2.1e-05 23.4 0.2 0.032 12.9 0.1 3.7 3 1 1 4 4 4 1 Nucleoporin Nup120/160 eIF2A PF08662.11 EOO02428.1 - 0.00058 19.8 0.0 0.0067 16.3 0.0 2.4 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 EOO02428.1 - 0.0019 17.3 0.0 2 7.4 0.0 3.2 3 1 1 4 4 4 2 VID27 C-terminal WD40-like domain Cytochrom_D1 PF02239.16 EOO02428.1 - 0.0053 15.3 0.0 0.014 14.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 EOO02428.1 - 0.012 14.5 0.3 0.17 10.8 0.4 2.5 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 EOO02428.1 - 0.03 12.7 0.0 0.82 7.9 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz zf-UBR PF02207.20 EOO02429.1 - 2.2e-18 66.2 16.3 5.9e-18 64.8 16.3 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EOO02429.1 - 0.0016 18.2 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Arf PF00025.21 EOO02430.1 - 9.2e-30 103.4 0.0 1e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EOO02430.1 - 4.4e-13 49.2 0.0 4.8e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EOO02430.1 - 7.4e-08 32.6 0.0 1.2e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EOO02430.1 - 1.5e-05 24.3 0.0 5.7e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 EOO02430.1 - 0.00018 21.0 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1_Xtn PF16897.5 EOO02430.1 - 0.05 13.6 0.1 0.079 13.0 0.1 1.4 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain F_bP_aldolase PF01116.20 EOO02431.1 - 4.1e-93 311.9 0.0 4.6e-93 311.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II FAD_binding_3 PF01494.19 EOO02432.1 - 6.1e-14 52.0 0.0 5.7e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 EOO02432.1 - 0.24 10.4 0.0 1.9 7.5 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Ribosomal_L9_N PF01281.19 EOO02434.1 - 1.1e-10 40.9 0.0 2e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 EOO02434.1 - 0.0024 18.3 0.0 0.0049 17.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain DSPc PF00782.20 EOO02435.1 - 8.7e-17 61.2 0.0 1.6e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DSPn PF14671.6 EOO02435.1 - 1.8e-06 28.4 0.0 0.00049 20.6 0.0 2.4 2 0 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half Y_phosphatase PF00102.27 EOO02435.1 - 3.4e-06 26.8 0.0 6.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EOO02435.1 - 0.23 11.5 1.5 0.35 11.0 0.0 2.0 2 1 0 2 2 2 0 Inositol hexakisphosphate Mago-bind PF09282.10 EOO02436.1 - 2.7e-14 52.7 1.7 5e-14 51.9 1.7 1.5 1 0 0 1 1 1 1 Mago binding Ammonium_transp PF00909.21 EOO02437.1 - 2e-116 389.0 31.4 2.3e-116 388.8 31.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family CBFD_NFYB_HMF PF00808.23 EOO02438.1 - 2.3e-09 37.4 0.2 4.3e-09 36.5 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EOO02438.1 - 1.1e-08 35.6 1.4 1.1e-08 35.6 1.4 2.2 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 EOO02438.1 - 0.002 18.2 0.4 0.0035 17.4 0.0 1.6 2 0 0 2 2 2 1 hTAFII28-like protein conserved region PPP4R2 PF09184.11 EOO02438.1 - 0.18 11.3 34.5 0.013 15.1 19.4 2.2 2 0 0 2 2 2 0 PPP4R2 TFIIA PF03153.13 EOO02438.1 - 0.34 10.9 27.0 0.48 10.4 27.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFB6 PF17110.5 EOO02438.1 - 4.4 7.0 15.9 13 5.5 0.3 3.2 3 0 0 3 3 3 0 Subunit 11 of the general transcription factor TFIIH GN3L_Grn1 PF08701.11 EOO02439.1 - 2.2e-25 88.5 16.8 4.6e-25 87.5 16.8 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EOO02439.1 - 4.1e-17 62.3 0.1 2.1e-12 47.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EOO02439.1 - 4.7e-08 33.1 0.0 7.7e-07 29.2 0.0 2.2 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 EOO02439.1 - 1.6e-06 28.2 4.1 0.092 12.8 0.2 3.8 2 2 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 EOO02439.1 - 9.1e-06 25.3 0.0 0.13 11.8 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EOO02439.1 - 0.00059 19.4 0.1 0.014 14.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 EOO02439.1 - 0.011 14.7 0.1 0.011 14.7 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Nuc_deoxyri_tr2 PF15891.5 EOO02439.1 - 0.075 13.4 0.4 0.94 9.8 0.0 2.4 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like Roc PF08477.13 EOO02439.1 - 0.17 12.1 0.0 21 5.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EOO02439.1 - 0.21 11.9 0.0 0.21 11.9 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain BCS1_N PF08740.11 EOO02440.1 - 3.7e-39 134.7 0.0 5.1e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EOO02440.1 - 7.2e-19 68.5 0.0 1.1e-18 68.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EOO02440.1 - 6.3e-05 23.4 0.0 0.00012 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EOO02440.1 - 0.00023 20.7 0.0 0.0004 19.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 EOO02440.1 - 0.00026 20.6 0.0 0.015 14.9 0.0 2.6 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 EOO02440.1 - 0.00068 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EOO02440.1 - 0.00078 19.5 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EOO02440.1 - 0.0074 15.5 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 EOO02440.1 - 0.0092 16.5 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 EOO02440.1 - 0.0098 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EOO02440.1 - 0.01 16.0 0.0 0.031 14.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EOO02440.1 - 0.014 15.7 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EOO02440.1 - 0.025 14.3 0.0 0.066 13.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EOO02440.1 - 0.025 15.1 0.0 0.051 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EOO02440.1 - 0.032 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.6 EOO02440.1 - 0.051 13.8 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EOO02440.1 - 0.059 13.8 0.0 0.14 12.5 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 EOO02440.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EOO02440.1 - 0.12 12.9 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EOO02440.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EOO02440.1 - 0.14 12.1 0.0 1.5 8.8 0.0 2.3 1 1 1 2 2 2 0 NACHT domain AAA_21 PF13304.6 EOO02440.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 EOO02440.1 - 0.16 11.7 0.0 0.41 10.4 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 EOO02440.1 - 0.25 11.1 0.0 0.42 10.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Glyco_hydro_15 PF00723.21 EOO02441.1 - 1.7e-65 221.6 0.0 6.8e-44 150.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EOO02441.1 - 1.4e-33 114.7 1.1 3.2e-33 113.5 1.1 1.7 1 0 0 1 1 1 1 Starch binding domain Peptidase_S66 PF02016.15 EOO02442.1 - 3.1e-27 95.1 0.0 4.4e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 EOO02442.1 - 3.7e-26 92.1 0.0 5.8e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain TauD PF02668.16 EOO02443.1 - 7e-15 55.5 0.1 1.5e-10 41.3 0.1 2.1 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EOO02443.1 - 0.043 12.9 0.1 0.066 12.3 0.1 1.2 1 0 0 1 1 1 0 CsiD IATP PF04568.12 EOO02444.1 - 9.3e-31 106.2 1.5 1.1e-30 106.0 1.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF489 PF04356.12 EOO02444.1 - 0.045 13.8 0.4 0.053 13.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF2205 PF10224.9 EOO02444.1 - 0.091 12.8 4.0 0.14 12.2 4.0 1.3 1 0 0 1 1 1 0 Short coiled-coil protein XhlA PF10779.9 EOO02444.1 - 0.16 12.2 2.1 0.23 11.7 2.1 1.3 1 0 0 1 1 1 0 Haemolysin XhlA NPV_P10 PF05531.12 EOO02444.1 - 0.17 12.3 1.1 0.25 11.8 1.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1003 PF06210.11 EOO02444.1 - 0.38 10.9 2.7 0.54 10.4 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) TspO_MBR PF03073.15 EOO02445.1 - 3.7e-45 153.3 5.5 4.5e-45 153.0 5.5 1.1 1 0 0 1 1 1 1 TspO/MBR family HAD_2 PF13419.6 EOO02446.1 - 3e-20 73.0 0.0 3.9e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EOO02446.1 - 4.7e-10 40.1 0.0 5.5e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EOO02446.1 - 5.4e-07 30.2 0.0 7.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EOO02446.1 - 6.3e-05 23.0 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EOO02446.1 - 0.0074 16.4 0.1 0.12 12.5 0.1 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase GHL6 PF14871.6 EOO02446.1 - 0.071 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 COesterase PF00135.28 EOO02447.1 - 4.7e-65 220.4 0.0 4e-53 181.0 0.2 2.8 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EOO02447.1 - 0.0001 22.2 0.1 0.0016 18.3 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold RNA_pol_Rpb2_6 PF00562.28 EOO02448.1 - 5.1e-114 381.3 0.1 6.6e-114 381.0 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 EOO02448.1 - 8.7e-29 99.5 0.0 1.9e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EOO02448.1 - 1.1e-27 97.0 0.0 1.7e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 EOO02448.1 - 3.3e-25 87.8 0.0 6.4e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 EOO02448.1 - 8.7e-16 58.1 0.0 2.6e-14 53.4 0.0 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 zinc_ribbon_15 PF17032.5 EOO02448.1 - 0.12 13.1 0.2 0.26 12.1 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon family Fringe PF02434.16 EOO02449.1 - 3.2e-06 26.8 0.1 4.8e-05 22.9 0.1 2.2 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.26 EOO02449.1 - 3.6e-05 23.6 0.1 6.3e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 PAN domain DJ-1_PfpI PF01965.24 EOO02450.1 - 6.4e-07 29.3 0.0 8.6e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family PGM_PMM_I PF02878.16 EOO02451.1 - 9.3e-33 112.9 0.0 1.4e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EOO02451.1 - 2.7e-26 92.0 0.0 5.1e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EOO02451.1 - 4.6e-15 56.1 0.0 1e-14 55.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EOO02451.1 - 6.7e-06 26.2 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain STIMATE PF12400.8 EOO02452.1 - 2e-41 141.5 1.8 2e-41 141.5 1.8 1.4 2 0 0 2 2 2 1 STIMATE family Iwr1 PF08574.10 EOO02452.1 - 0.89 10.6 6.1 8.4 7.5 1.9 2.4 2 0 0 2 2 2 0 Transcription factor Iwr1 His_Phos_2 PF00328.22 EOO02453.1 - 3.4e-50 171.5 0.0 3.9e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HET PF06985.11 EOO02454.1 - 5.6e-24 85.2 0.0 1e-23 84.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) E1-E2_ATPase PF00122.20 EOO02455.1 - 5.9e-38 130.2 1.7 1.2e-37 129.2 0.5 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EOO02455.1 - 2.7e-26 92.4 1.5 2.7e-26 92.4 1.5 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EOO02455.1 - 1.6e-19 69.7 0.0 3.3e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EOO02455.1 - 5.3e-17 62.8 0.0 2e-16 60.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EOO02455.1 - 0.00022 21.1 0.4 0.0069 16.2 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Abhydrolase_9_N PF15420.6 EOO02455.1 - 1.2 9.0 5.4 0.44 10.5 1.3 2.2 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus RabGAP-TBC PF00566.18 EOO02456.1 - 3.2e-30 105.4 0.0 9.7e-25 87.5 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain HTH_30 PF13556.6 EOO02456.1 - 0.082 12.7 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Mitoc_mL59 PF18126.1 EOO02457.1 - 2.8e-47 160.2 2.4 4.6e-47 159.5 2.4 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 zf-CSL PF05207.13 EOO02457.1 - 1.5e-19 69.5 0.4 2.2e-19 68.9 0.4 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 EOO02457.1 - 5e-12 45.8 0.1 1.1e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DUF2694 PF10904.8 EOO02457.1 - 0.18 11.9 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) Ribosomal_L35p PF01632.19 EOO02457.1 - 0.72 10.4 4.5 0.53 10.8 2.0 2.0 1 1 1 2 2 2 0 Ribosomal protein L35 Tim44 PF04280.15 EOO02458.1 - 1.2e-36 126.1 0.1 4.2e-36 124.3 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain HMG_box PF00505.19 EOO02459.1 - 2.2e-25 88.9 1.3 2.9e-25 88.5 1.3 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EOO02459.1 - 1.1e-17 64.4 1.8 1.5e-17 63.9 1.8 1.2 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 EOO02459.1 - 0.00085 19.9 1.2 0.0035 17.9 0.0 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 EOO02459.1 - 0.01 15.8 0.3 0.024 14.6 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box 5 CHDNT PF08073.12 EOO02459.1 - 0.072 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain NmrA PF05368.13 EOO02461.1 - 2e-09 37.4 0.0 3.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO02461.1 - 1.3e-08 34.9 0.0 2.3e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EOO02461.1 - 1.8e-06 27.6 0.1 2.7e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EOO02461.1 - 1.2e-05 25.3 0.2 2.3e-05 24.4 0.2 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EOO02461.1 - 0.0077 16.8 3.6 0.69 10.5 0.1 2.9 2 1 1 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 EOO02461.1 - 0.0083 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 EOO02461.1 - 0.0094 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family LpxI_N PF17930.1 EOO02461.1 - 0.016 15.1 0.2 0.54 10.2 0.1 2.5 2 0 0 2 2 2 0 LpxI N-terminal domain Sacchrp_dh_NADP PF03435.18 EOO02461.1 - 0.043 14.1 0.1 0.072 13.4 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EOO02461.1 - 0.044 12.9 0.1 0.081 12.0 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein bact-PGI_C PF10432.9 EOO02462.1 - 2.6e-07 30.8 0.0 4.7e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial phospho-glucose isomerase C-terminal SIS domain AAA PF00004.29 EOO02463.1 - 1.3e-40 138.9 0.0 2.2e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EOO02463.1 - 6.9e-07 29.0 0.0 1.7e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EOO02463.1 - 6.4e-05 23.0 0.1 0.00043 20.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EOO02463.1 - 0.00011 22.5 0.0 0.0069 16.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EOO02463.1 - 0.00027 21.1 0.0 0.00083 19.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EOO02463.1 - 0.00066 20.1 0.1 0.014 15.8 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EOO02463.1 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EOO02463.1 - 0.008 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EOO02463.1 - 0.023 15.0 0.1 0.063 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EOO02463.1 - 0.034 13.6 0.0 0.097 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EOO02463.1 - 0.05 13.8 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EOO02463.1 - 0.06 13.1 0.1 0.59 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EOO02463.1 - 0.062 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 EOO02463.1 - 0.081 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EOO02463.1 - 0.086 12.7 0.4 11 5.9 0.0 2.9 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EOO02463.1 - 0.086 12.5 0.1 0.28 10.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EOO02463.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EOO02463.1 - 0.17 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Exo_endo_phos PF03372.23 EOO02464.1 - 1e-14 54.7 0.3 1.5e-14 54.1 0.3 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ank_5 PF13857.6 EOO02465.1 - 5.2e-14 52.1 0.0 4e-13 49.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EOO02465.1 - 0.00011 22.7 0.0 0.0038 17.8 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EOO02465.1 - 0.0003 21.0 0.0 0.12 13.0 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EOO02465.1 - 0.0024 18.4 0.0 0.006 17.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EOO02465.1 - 0.0063 16.9 0.0 4.2 8.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat PX PF00787.24 EOO02465.1 - 0.0067 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 PX domain AAA_11 PF13086.6 EOO02466.1 - 1.2e-59 202.2 0.5 4.1e-59 200.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EOO02466.1 - 1.6e-28 99.7 0.0 3.4e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EOO02466.1 - 1.1e-11 44.9 0.0 2.2e-10 40.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EOO02466.1 - 7.1e-08 32.9 0.0 2.1e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EOO02466.1 - 6.7e-06 25.6 0.5 3.1e-05 23.4 0.5 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 EOO02466.1 - 7.6e-06 25.7 0.1 2.7e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 EOO02466.1 - 3.2e-05 24.0 0.0 0.00019 21.5 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 EOO02466.1 - 0.00023 20.8 0.3 0.095 12.3 0.0 3.9 3 1 2 5 5 5 1 AAA domain Viral_helicase1 PF01443.18 EOO02466.1 - 0.00023 21.0 0.0 0.29 10.9 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 EOO02466.1 - 0.00052 20.4 0.1 0.0013 19.2 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain DEAD PF00270.29 EOO02466.1 - 0.00053 19.8 0.1 0.01 15.6 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EOO02466.1 - 0.00078 19.7 0.1 0.024 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 EOO02466.1 - 0.00089 19.2 0.0 0.094 12.6 0.0 2.4 2 0 0 2 2 2 1 Helicase Flavi_DEAD PF07652.14 EOO02466.1 - 0.0016 18.5 0.1 0.01 15.8 0.0 2.3 3 0 0 3 3 2 1 Flavivirus DEAD domain T2SSE PF00437.20 EOO02466.1 - 0.0023 17.0 0.6 0.0061 15.7 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 EOO02466.1 - 0.0065 16.2 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 EOO02466.1 - 0.012 16.0 0.6 0.083 13.3 0.0 2.5 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EOO02466.1 - 0.018 14.5 0.0 0.13 11.7 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein TrwB_AAD_bind PF10412.9 EOO02466.1 - 0.026 13.4 0.0 0.051 12.5 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 EOO02466.1 - 0.043 13.5 0.0 0.24 11.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EOO02466.1 - 0.078 13.0 0.0 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PCB_OB PF17092.5 EOO02466.1 - 0.094 13.5 3.6 79 4.1 0.0 4.2 3 1 1 4 4 4 0 Penicillin-binding protein OB-like domain FtsK_SpoIIIE PF01580.18 EOO02466.1 - 0.11 11.9 2.2 3.3 7.0 0.0 3.5 4 1 1 5 5 5 0 FtsK/SpoIIIE family RNB PF00773.19 EOO02468.1 - 3.5e-97 325.7 0.0 5.1e-97 325.1 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 EOO02468.1 - 7.4e-31 106.0 0.0 2.4e-30 104.3 0.0 2.0 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 EOO02468.1 - 1.5e-27 96.1 0.0 3.5e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 EOO02468.1 - 1.2e-20 73.3 0.0 3.1e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EOO02468.1 - 1.4e-09 38.3 0.2 9.3e-09 35.7 0.0 2.5 2 1 0 2 2 2 1 PIN domain CSD2 PF17876.1 EOO02468.1 - 7.7e-08 32.4 0.0 0.0023 18.0 0.0 3.3 3 0 0 3 3 3 2 Cold shock domain OB_RNB PF08206.11 EOO02468.1 - 0.13 11.9 0.0 0.48 10.1 0.0 2.0 1 0 0 1 1 1 0 Ribonuclease B OB domain CENP-H PF05837.12 EOO02469.1 - 1.9e-38 131.3 10.6 8.9e-37 125.9 6.8 2.0 2 0 0 2 2 2 2 Centromere protein H (CENP-H) FlxA PF14282.6 EOO02469.1 - 0.023 14.7 2.9 0.088 12.8 0.9 2.2 2 0 0 2 2 2 0 FlxA-like protein DUF2721 PF11026.8 EOO02469.1 - 0.83 9.5 3.2 26 4.7 1.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) COG2 PF06148.11 EOO02469.1 - 0.92 9.6 6.8 0.4 10.8 1.8 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Fez1 PF06818.15 EOO02469.1 - 1.2 9.5 12.6 5.1 7.5 12.6 1.8 1 1 0 1 1 1 0 Fez1 TMCO5 PF14992.6 EOO02469.1 - 3.6 7.1 11.8 17 4.9 11.8 1.9 1 1 0 1 1 1 0 TMCO5 family MCRS_N PF13325.6 EOO02469.1 - 3.7 7.5 11.8 1 9.3 3.6 2.2 2 0 0 2 2 2 0 N-terminal region of micro-spherule protein MRPL52 PF18699.1 EOO02469.1 - 4.2 7.6 7.7 1.4 9.2 2.8 2.3 2 0 0 2 2 2 0 Mitoribosomal protein mL52 YabA PF06156.13 EOO02469.1 - 5.4 7.7 10.3 1.2 9.8 2.8 2.4 2 1 0 2 2 2 0 Initiation control protein YabA FmiP_Thoc5 PF09766.9 EOO02470.1 - 5.2e-32 111.5 13.3 5.2e-32 111.5 13.3 1.4 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 SPATA1_C PF15743.5 EOO02470.1 - 0.0016 18.6 4.9 0.0016 18.6 4.9 2.4 2 1 0 2 2 2 1 Spermatogenesis-associated C-terminus DUF87 PF01935.17 EOO02470.1 - 0.012 15.7 5.6 0.015 15.4 5.6 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain Microvir_H PF04687.12 EOO02470.1 - 0.12 11.7 0.8 0.19 11.1 0.8 1.3 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) YabA PF06156.13 EOO02470.1 - 0.15 12.7 13.2 1.1 10.0 2.6 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Casc1_N PF15927.5 EOO02470.1 - 0.3 10.7 23.1 0.029 14.1 9.1 2.3 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Cortex-I_coil PF09304.10 EOO02470.1 - 1.4 9.1 16.0 0.84 9.9 4.8 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF4407 PF14362.6 EOO02470.1 - 1.6 8.0 14.4 2.3 7.5 14.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EOO02470.1 - 1.8 8.6 6.4 3.1 7.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DOR PF14839.6 EOO02470.1 - 4.5 7.2 8.8 1.1 9.2 3.4 2.0 2 0 0 2 2 2 0 DOR family V_ATPase_I PF01496.19 EOO02470.1 - 5.9 4.7 7.6 6.8 4.5 7.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.6 EOO02470.1 - 8 6.9 24.1 8.6 6.8 8.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) RRM_1 PF00076.22 EOO02471.1 - 4.4e-19 68.1 0.7 1.1e-18 66.8 0.3 1.8 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EOO02471.1 - 1.4e-05 24.6 0.1 1.7e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EOO02471.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Frankia_peptide PF14407.6 EOO02471.1 - 0.064 13.2 0.0 1.3 9.1 0.0 2.5 2 1 1 3 3 3 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. GFO_IDH_MocA PF01408.22 EOO02472.1 - 5.8e-13 49.7 0.0 1.4e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EOO02472.1 - 0.00048 20.1 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ImpA_N PF06812.12 EOO02472.1 - 0.029 14.5 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system DUF1768 PF08719.11 EOO02473.1 - 5.9e-58 195.7 0.0 6.8e-58 195.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Oxysterol_BP PF01237.18 EOO02474.1 - 1.6e-60 205.0 0.1 2.8e-58 197.5 0.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein RNase_T PF00929.24 EOO02475.1 - 5.2e-31 108.4 0.2 6e-31 108.2 0.2 1.0 1 0 0 1 1 1 1 Exonuclease HK97-gp10_like PF04883.12 EOO02475.1 - 0.027 15.4 0.4 7.8 7.6 0.1 2.3 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component DUF3622 PF12286.8 EOO02475.1 - 0.037 14.4 0.1 0.11 12.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3622) HlyIII PF03006.20 EOO02476.1 - 9.5e-60 202.1 19.7 1.2e-59 201.8 19.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF883 PF05957.13 EOO02476.1 - 0.12 13.0 6.7 0.68 10.6 1.0 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YchF-GTPase_C PF06071.13 EOO02477.1 - 2e-35 120.8 0.2 5.9e-35 119.3 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EOO02477.1 - 1.7e-16 60.3 0.0 6.1e-16 58.5 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 EOO02477.1 - 0.00028 20.9 0.1 0.00067 19.7 0.1 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EOO02477.1 - 0.0005 19.6 0.0 0.00092 18.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AKAP95 PF04988.12 EOO02477.1 - 0.099 12.9 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) BetaGal_dom3 PF13363.6 EOO02477.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 AAA_23 PF13476.6 EOO02477.1 - 2.5 8.5 7.2 9.6 6.6 0.1 2.3 1 1 0 2 2 2 0 AAA domain SnoaL_2 PF12680.7 EOO02479.1 - 0.077 13.6 0.0 0.2 12.3 0.0 1.6 1 1 0 1 1 1 0 SnoaL-like domain Alpha-amylase PF00128.24 EOO02480.1 - 3.6e-21 76.1 0.0 5.6e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EOO02480.1 - 5e-06 26.7 0.1 3.8e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) DUF4504 PF14953.6 EOO02480.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) FTA2 PF13095.6 EOO02481.1 - 1.1e-63 214.8 0.0 1.4e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Ppx-GppA PF02541.16 EOO02482.1 - 3.7e-32 111.9 0.0 6.2e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Minor_capsid_3 PF12691.7 EOO02482.1 - 0.2 12.0 0.0 0.43 11.0 0.0 1.5 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage Peptidase_S8 PF00082.22 EOO02483.1 - 2.5e-21 76.2 0.1 3.7e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Nsp1_C PF05064.13 EOO02484.1 - 9.6e-36 122.1 7.7 9.6e-36 122.1 7.7 1.7 2 1 0 2 2 2 1 Nsp1-like C-terminal region RSS_P20 PF11757.8 EOO02484.1 - 0.002 18.5 0.3 0.16 12.5 0.1 2.3 2 0 0 2 2 2 1 Suppressor of RNA silencing P21-like N-terminal domain NPV_P10 PF05531.12 EOO02484.1 - 0.0035 17.8 3.9 3.3 8.3 0.0 3.4 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein EzrA PF06160.12 EOO02484.1 - 0.0053 15.0 6.4 0.15 10.2 0.0 2.0 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA Lipoprotein_6 PF01441.19 EOO02484.1 - 0.0081 16.2 0.3 0.021 14.8 0.1 1.7 2 0 0 2 2 2 1 Lipoprotein Myosin_tail_1 PF01576.19 EOO02484.1 - 0.0083 14.0 5.5 0.0086 14.0 5.5 1.1 1 0 0 1 1 1 1 Myosin tail ING PF12998.7 EOO02484.1 - 0.012 16.2 2.7 0.4 11.3 1.3 2.8 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Baculo_PEP_C PF04513.12 EOO02484.1 - 0.014 15.5 4.0 0.38 10.8 0.1 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.6 EOO02484.1 - 0.015 15.7 6.0 0.47 10.9 3.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF1664 PF07889.12 EOO02484.1 - 0.025 14.6 3.5 2.3 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4164 PF13747.6 EOO02484.1 - 0.048 13.9 2.9 0.34 11.2 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) CorA PF01544.18 EOO02484.1 - 0.061 12.6 4.6 1.8 7.8 2.3 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF948 PF06103.11 EOO02484.1 - 0.078 13.2 3.3 0.33 11.2 0.2 2.6 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CAMP_factor PF07373.11 EOO02484.1 - 0.082 12.5 1.3 0.67 9.5 0.1 2.1 2 0 0 2 2 2 0 CAMP factor (Cfa) Nup88 PF10168.9 EOO02484.1 - 0.088 10.6 2.3 0.1 10.4 2.3 1.1 1 0 0 1 1 1 0 Nuclear pore component PI_PP_I PF18363.1 EOO02484.1 - 0.14 12.4 5.1 0.093 12.9 2.4 2.0 2 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain MscS_porin PF12795.7 EOO02484.1 - 0.15 11.6 14.9 0.17 11.4 9.0 2.5 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain YabA PF06156.13 EOO02484.1 - 0.22 12.2 3.2 2 9.1 0.0 2.4 2 1 0 2 2 2 0 Initiation control protein YabA HSBP1 PF06825.12 EOO02484.1 - 0.22 11.4 1.9 1.3 8.9 0.3 2.6 2 1 0 2 2 2 0 Heat shock factor binding protein 1 FlaC_arch PF05377.11 EOO02484.1 - 0.23 11.9 2.0 8 6.9 0.3 2.8 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) V-SNARE PF05008.15 EOO02484.1 - 0.24 11.8 6.6 0.76 10.2 1.0 3.2 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF16 PF01519.16 EOO02484.1 - 0.31 11.6 8.0 11 6.6 7.0 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 MIP-T3_C PF17749.1 EOO02484.1 - 0.31 11.0 10.4 0.7 9.8 0.1 3.3 3 1 0 3 3 2 0 Microtubule-binding protein MIP-T3 C-terminal region OmpH PF03938.14 EOO02484.1 - 0.35 11.2 12.4 1.7 9.0 5.9 2.9 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) CLZ PF16526.5 EOO02484.1 - 0.43 11.0 6.1 22 5.5 0.1 3.4 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tropomyosin_1 PF12718.7 EOO02484.1 - 0.46 10.6 9.2 2.1 8.5 4.4 2.7 1 1 2 3 3 3 0 Tropomyosin like Prominin PF05478.11 EOO02484.1 - 0.55 8.1 4.0 1.5 6.7 1.3 2.0 2 0 0 2 2 2 0 Prominin Syntaxin-6_N PF09177.11 EOO02484.1 - 0.56 10.8 6.8 2 9.0 4.6 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Laminin_II PF06009.12 EOO02484.1 - 0.6 10.1 6.1 5.4 7.0 0.7 2.6 1 1 1 2 2 2 0 Laminin Domain II AAA_13 PF13166.6 EOO02484.1 - 0.71 8.5 6.6 4.8 5.7 6.8 1.8 1 1 0 1 1 1 0 AAA domain TACC_C PF05010.14 EOO02484.1 - 0.86 9.4 9.6 0.31 10.8 5.6 2.2 1 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BLOC1_2 PF10046.9 EOO02484.1 - 2 8.8 9.0 23 5.4 0.1 3.1 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Jnk-SapK_ap_N PF09744.9 EOO02484.1 - 2.8 8.2 9.8 4.4 7.5 8.3 2.1 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 EOO02484.1 - 2.9 8.4 11.7 12 6.5 8.4 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 EOO02484.1 - 3.5 7.9 8.1 7.2 6.9 0.4 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.8 EOO02484.1 - 8.2 5.7 14.1 8.5 5.6 7.8 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) 14-3-3 PF00244.20 EOO02485.1 - 5.6e-107 356.3 2.5 6.6e-107 356.1 2.5 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 EOO02485.1 - 0.22 12.1 3.1 0.74 10.4 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 EOO02486.1 - 4.2e-08 32.9 0.0 5.5e-06 25.9 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EOO02486.1 - 0.0022 17.3 0.0 0.44 9.8 0.0 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase MFS_1 PF07690.16 EOO02487.1 - 2.3e-13 49.8 47.8 5.7e-12 45.2 44.4 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 EOO02487.1 - 3.5e-05 23.0 10.2 0.00015 20.9 6.6 2.6 3 0 0 3 3 3 2 PUCC protein TRI12 PF06609.13 EOO02487.1 - 0.00011 20.8 15.3 0.0002 19.9 15.3 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short_C2 PF13561.6 EOO02488.1 - 2e-60 204.3 1.0 2.3e-60 204.0 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO02488.1 - 3.9e-39 134.1 0.8 5.5e-39 133.6 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO02488.1 - 3.8e-10 40.0 0.3 5.3e-10 39.5 0.3 1.1 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 EOO02488.1 - 8.9e-05 22.4 0.1 0.00015 21.7 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus PALP PF00291.25 EOO02488.1 - 0.025 14.0 0.4 0.039 13.4 0.4 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme NADH5_C PF06455.11 EOO02488.1 - 0.082 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus Herpes_UL87 PF03043.14 EOO02488.1 - 0.11 11.0 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family adh_short_C2 PF13561.6 EOO02489.1 - 5.6e-50 170.1 1.2 4.5e-48 163.9 1.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO02489.1 - 1.4e-35 122.5 0.7 4.9e-24 84.9 0.6 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 EOO02489.1 - 6.4e-08 32.7 0.3 9.6e-08 32.1 0.3 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO02489.1 - 1.9e-06 27.5 0.2 0.014 14.8 0.3 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family DUF3546 PF12066.8 EOO02490.1 - 3.6e-35 120.5 1.5 3.6e-35 120.5 1.5 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 EOO02490.1 - 1.5e-12 47.1 0.1 3.9e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 EOO02490.1 - 4.8e-12 46.7 9.0 3.2e-11 44.0 9.0 2.5 1 1 0 1 1 1 1 Arsenite-resistance protein 2 RCR PF12273.8 EOO02491.1 - 4.1e-28 98.4 8.8 5.6e-28 98.0 8.8 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SARAF PF06682.12 EOO02491.1 - 0.00016 21.4 0.2 0.00023 21.0 0.1 1.3 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis PDR_assoc PF08370.11 EOO02491.1 - 0.035 13.8 1.3 0.062 13.1 1.3 1.3 1 0 0 1 1 1 0 Plant PDR ABC transporter associated Orthoreo_P10 PF07204.11 EOO02491.1 - 0.062 13.3 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DEAD PF00270.29 EOO02492.1 - 2.3e-48 164.3 0.0 2.1e-47 161.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EOO02492.1 - 1.2e-28 99.7 0.1 4.9e-28 97.7 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO02492.1 - 0.00085 19.4 0.0 0.0036 17.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PRAI PF00697.22 EOO02492.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Selenoprotein_S PF06936.11 EOO02494.1 - 0.006 16.4 2.0 0.0077 16.1 2.0 1.1 1 0 0 1 1 1 1 Selenoprotein S (SelS) FAD_binding_3 PF01494.19 EOO02495.1 - 8.3e-18 64.7 0.1 4.7e-17 62.3 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EOO02495.1 - 0.0012 18.2 0.3 0.18 11.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EOO02495.1 - 0.0017 18.9 0.0 0.011 16.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EOO02495.1 - 0.015 14.9 1.1 0.15 11.6 0.4 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EOO02495.1 - 0.02 15.1 0.1 0.17 12.2 0.1 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EOO02495.1 - 0.12 11.7 0.1 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RNA_pol PF00940.19 EOO02496.1 - 4.8e-187 621.9 0.0 7.3e-187 621.3 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EOO02496.1 - 6.5e-106 354.5 0.4 1e-105 353.9 0.4 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DHHA2 PF02833.14 EOO02497.1 - 2e-36 125.3 0.7 2.9e-36 124.8 0.7 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 EOO02497.1 - 1.1e-08 35.2 0.0 2.5e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 DHH family RsfS PF02410.15 EOO02498.1 - 9.8e-10 38.8 0.0 5.6e-09 36.3 0.0 2.3 2 1 0 2 2 2 1 Ribosomal silencing factor during starvation mRNA_stabil PF13929.6 EOO02498.1 - 0.00011 21.3 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 mRNA stabilisation S1-P1_nuclease PF02265.16 EOO02499.1 - 4.7e-71 239.6 0.1 5.4e-71 239.4 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease GATase PF00117.28 EOO02500.1 - 3.6e-11 43.2 0.0 4.4e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EOO02500.1 - 0.061 12.9 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GMC_oxred_N PF00732.19 EOO02501.1 - 9.7e-53 179.4 0.0 1.2e-52 179.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EOO02501.1 - 5.4e-32 111.3 0.0 9.1e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EOO02501.1 - 0.0058 15.8 2.1 1.9 7.4 2.3 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EOO02501.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EOO02501.1 - 0.03 13.6 0.4 0.065 12.5 0.2 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 EOO02501.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EOO02501.1 - 0.2 10.9 0.9 6.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ring_hydroxyl_A PF00848.19 EOO02502.1 - 6.1e-18 65.6 1.3 1.3e-11 44.9 1.2 2.5 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 EOO02502.1 - 6.8e-15 54.8 0.0 1.5e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DnaJ PF00226.31 EOO02502.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain FAD_binding_3 PF01494.19 EOO02504.1 - 2.4e-28 99.4 0.7 4e-21 75.7 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EOO02504.1 - 6e-07 29.4 0.4 0.013 15.1 0.1 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EOO02504.1 - 2.7e-06 26.9 0.2 0.015 14.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EOO02504.1 - 9.4e-05 21.4 0.4 0.13 11.0 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 EOO02504.1 - 0.00029 21.0 0.0 0.00091 19.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EOO02504.1 - 0.00067 18.5 0.0 0.11 11.2 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 EOO02504.1 - 0.016 15.8 0.0 0.1 13.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EOO02504.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 EOO02505.1 - 9.8e-39 133.3 51.1 5.5e-38 130.8 51.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily UvrA_DNA-bind PF17755.1 EOO02506.1 - 4.2e-14 52.8 0.0 7e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 UvrA DNA-binding domain ABC_tran PF00005.27 EOO02506.1 - 5.3e-12 46.4 0.0 8.6e-08 32.8 0.0 3.4 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 EOO02506.1 - 5.9e-07 29.6 3.1 0.054 13.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DnaJ_CXXCXGXG PF00684.19 EOO02506.1 - 6.4e-05 23.2 1.7 0.051 13.9 0.2 3.2 3 0 0 3 3 3 1 DnaJ central domain AAA_16 PF13191.6 EOO02506.1 - 0.0012 19.3 0.7 0.014 15.8 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_15 PF13175.6 EOO02506.1 - 0.0024 17.7 0.0 11 5.5 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 EOO02506.1 - 0.0056 16.4 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MeaB PF03308.16 EOO02506.1 - 0.021 13.8 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 EOO02506.1 - 0.022 14.7 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 EOO02506.1 - 0.044 14.0 0.0 0.095 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EOO02506.1 - 0.046 13.3 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EOO02506.1 - 0.052 13.8 0.0 0.22 11.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EOO02506.1 - 0.052 13.3 0.1 0.082 12.6 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 EOO02506.1 - 0.098 12.6 0.2 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 EOO02506.1 - 0.098 12.6 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 NACHT domain DUF463 PF04317.12 EOO02506.1 - 0.099 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 DUF2075 PF09848.9 EOO02506.1 - 0.12 11.6 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.14 EOO02506.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Anti-TRAP PF15777.5 EOO02506.1 - 1.6 8.8 5.0 18 5.4 0.2 3.2 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Catalase PF00199.19 EOO02507.1 - 4.1e-87 292.8 0.3 5e-87 292.5 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EOO02507.1 - 0.00026 21.1 0.0 0.00067 19.8 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive PTR2 PF00854.21 EOO02508.1 - 5.6e-58 196.7 7.5 8.5e-58 196.1 7.5 1.3 1 0 0 1 1 1 1 POT family ZYG-11_interact PF05884.12 EOO02508.1 - 7.9 5.8 13.8 2.4 7.5 2.3 2.4 2 0 0 2 2 2 0 Interactor of ZYG-11 AA_permease PF00324.21 EOO02509.1 - 4.2e-100 335.6 38.2 5.2e-100 335.3 38.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EOO02509.1 - 5.1e-25 88.2 44.3 6.9e-25 87.7 44.3 1.2 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_127 PF07944.12 EOO02510.1 - 5.6e-95 318.8 0.0 9.3e-95 318.1 0.0 1.3 1 1 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_transf_28 PF03033.20 EOO02511.1 - 7.1e-17 61.8 0.0 2.6e-16 59.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain F-box PF00646.33 EOO02512.1 - 0.0034 17.2 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EOO02512.1 - 0.007 16.2 0.1 0.075 12.9 0.0 2.3 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 EOO02512.1 - 0.0092 15.9 0.1 0.028 14.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like OPT PF03169.15 EOO02514.1 - 1.1e-148 496.6 46.5 1.3e-148 496.4 46.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DAO PF01266.24 EOO02515.1 - 7.4e-22 78.4 0.0 9.7e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_C PF05199.13 EOO02516.1 - 5.7e-20 72.3 0.0 8.1e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Hydantoinase_B PF02538.14 EOO02517.1 - 4e-122 408.2 0.2 5.9e-122 407.7 0.2 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EOO02517.1 - 1.1e-102 343.2 0.4 8e-102 340.4 0.1 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EOO02517.1 - 2e-59 200.3 0.2 1.3e-57 194.4 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region TIP120 PF08623.10 EOO02518.1 - 0.054 13.3 2.6 0.058 13.2 2.6 1.1 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Laterosporulin PF17861.1 EOO02518.1 - 0.11 12.9 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Laterosporulin defensin-like peptide DUF3450 PF11932.8 EOO02518.1 - 0.12 11.7 4.7 0.14 11.4 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GCV_T PF01571.21 EOO02519.1 - 1.5e-67 227.7 0.0 2.1e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 EOO02519.1 - 1.1e-42 146.9 0.6 1.9e-42 146.1 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 EOO02519.1 - 4.1e-22 77.9 0.2 1.1e-21 76.5 0.2 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 EOO02519.1 - 4.5e-19 68.5 0.0 1.1e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox PF00070.27 EOO02519.1 - 1.4e-05 25.5 0.2 0.0039 17.7 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EOO02519.1 - 8.8e-05 21.9 0.2 0.021 14.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EOO02519.1 - 0.00025 20.3 0.1 0.00038 19.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 EOO02519.1 - 0.0017 18.6 0.0 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Trp_halogenase PF04820.14 EOO02519.1 - 0.0064 15.4 0.2 0.028 13.3 0.0 1.9 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 EOO02519.1 - 0.023 14.9 0.0 0.075 13.3 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 EOO02519.1 - 0.025 14.7 0.1 0.047 13.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 EOO02519.1 - 0.15 12.0 0.2 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EOO02519.1 - 0.21 10.8 0.4 1.1 8.4 0.4 1.9 1 1 0 1 1 1 0 FAD binding domain ketoacyl-synt PF00109.26 EOO02520.1 - 1.7e-64 217.8 0.1 1.7e-64 217.8 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EOO02520.1 - 4.5e-62 210.0 0.1 9.8e-62 208.9 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EOO02520.1 - 5.7e-60 202.3 0.0 1.2e-59 201.3 0.0 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EOO02520.1 - 2.2e-41 142.4 0.2 4.3e-41 141.4 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EOO02520.1 - 1e-38 132.0 0.0 2.9e-38 130.5 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EOO02520.1 - 8.6e-18 64.8 0.0 2.6e-17 63.3 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EOO02520.1 - 1.9e-17 63.8 0.0 5.5e-17 62.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EOO02520.1 - 2.1e-13 51.5 0.0 7e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EOO02520.1 - 3.5e-13 49.5 0.0 2e-12 47.0 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 EOO02520.1 - 1.5e-11 44.3 6.3 7.1e-11 42.2 0.0 3.7 3 1 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EOO02520.1 - 4.5e-10 39.6 0.0 9.3e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO02520.1 - 9.8e-10 39.0 0.0 4.4e-09 36.9 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO02520.1 - 1.5e-06 28.1 0.0 4.7e-06 26.5 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EOO02520.1 - 3.2e-06 26.9 0.0 1.6e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_11 PF08241.12 EOO02520.1 - 4.2e-06 27.3 0.2 1.9e-05 25.2 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 EOO02520.1 - 3.1e-05 24.2 0.7 0.00018 21.8 0.6 2.5 3 0 0 3 3 2 1 Phosphopantetheine attachment site ADH_N PF08240.12 EOO02520.1 - 0.00013 21.8 0.2 0.00028 20.7 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 EOO02520.1 - 0.032 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 EOO02520.1 - 0.06 14.4 0.0 0.24 12.4 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain IU_nuc_hydro PF01156.19 EOO02521.1 - 2.2e-32 112.9 0.0 2.8e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MFS_1 PF07690.16 EOO02522.1 - 5.9e-30 104.4 12.4 7.7e-30 104.0 12.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily 7TM-7TMR_HD PF07698.11 EOO02522.1 - 0.0026 17.5 0.5 0.0026 17.5 0.5 2.5 2 1 0 2 2 2 1 7TM receptor with intracellular HD hydrolase IFT57 PF10498.9 EOO02524.1 - 0.068 12.1 0.5 0.15 11.0 0.6 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.12 EOO02524.1 - 0.14 12.2 0.5 1 9.4 0.2 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TRAF_BIRC3_bd PF16673.5 EOO02524.1 - 0.18 11.6 2.3 27 4.6 0.0 3.9 4 1 1 5 5 5 0 TNF receptor-associated factor BIRC3 binding domain YlqD PF11068.8 EOO02524.1 - 0.31 11.4 3.0 7.6 6.9 0.7 2.2 1 1 1 2 2 2 0 YlqD protein TPP_enzyme_N PF02776.18 EOO02525.1 - 5.1e-32 110.9 0.0 9.6e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EOO02525.1 - 1.1e-14 54.4 0.1 3.1e-14 53.0 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EOO02525.1 - 1.9e-09 37.3 0.0 5.5e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain E1_dh PF00676.20 EOO02525.1 - 0.07 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Thiol_cytolysin PF01289.19 EOO02525.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Thiol-activated cytolysin Histone_H2A_C PF16211.5 EOO02526.1 - 2.2e-21 75.3 3.1 3.8e-21 74.5 3.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EOO02526.1 - 6.9e-17 62.0 0.0 9.3e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EOO02526.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LcrG PF07216.12 EOO02526.1 - 0.093 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 LcrG protein DnaJ PF00226.31 EOO02527.1 - 3.2e-22 78.4 2.7 8.1e-22 77.1 2.7 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 EOO02527.1 - 9.3e-11 41.1 0.1 0.00056 19.6 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EOO02527.1 - 1.2e-10 40.7 4.6 0.035 14.2 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EOO02527.1 - 2.3e-10 40.4 1.3 0.12 13.2 0.3 6.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EOO02527.1 - 8.1e-10 38.1 0.5 0.01 16.0 0.0 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EOO02527.1 - 2.8e-09 37.0 0.1 1.3e-05 25.3 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EOO02527.1 - 7.5e-08 32.8 1.4 0.0012 19.3 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EOO02527.1 - 9.1e-07 28.5 0.2 0.11 12.2 0.0 3.9 2 1 1 3 3 3 3 TPR repeat TPR_16 PF13432.6 EOO02527.1 - 4.1e-06 27.3 7.5 0.19 12.4 0.3 5.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EOO02527.1 - 9.8e-06 25.9 4.8 7.8 7.4 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 EOO02527.1 - 0.00015 21.9 0.5 0.041 14.3 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat PknG_TPR PF16918.5 EOO02527.1 - 0.00022 20.1 0.1 0.0041 15.9 0.0 2.6 3 1 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_7 PF13176.6 EOO02527.1 - 0.00024 20.9 4.5 0.13 12.4 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EOO02527.1 - 0.0077 16.5 6.3 0.19 12.0 0.1 3.9 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EOO02527.1 - 0.13 11.5 5.6 17 4.5 0.0 4.1 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EOO02527.1 - 0.34 11.3 4.1 4.1 7.8 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MIF4G PF02854.19 EOO02528.1 - 2.1e-23 83.1 0.6 1.4e-20 73.8 0.1 2.2 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.17 EOO02528.1 - 3e-18 65.8 0.0 7.8e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 MA3 domain COPI_C PF06957.11 EOO02528.1 - 0.016 14.0 3.0 0.044 12.5 3.0 1.7 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Pyr_redox_2 PF07992.14 EOO02529.1 - 6.2e-69 232.5 6.2 9.7e-69 231.8 6.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EOO02529.1 - 9.2e-40 135.3 0.0 3e-39 133.7 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EOO02529.1 - 2.5e-24 85.6 11.4 1.8e-21 76.5 1.3 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EOO02529.1 - 8.2e-12 45.2 2.5 1.5e-06 28.3 0.5 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EOO02529.1 - 3e-10 39.7 3.3 6.1e-08 32.2 0.7 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EOO02529.1 - 5.6e-10 39.1 6.5 3.7e-09 36.5 0.2 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EOO02529.1 - 9.9e-09 34.8 7.4 6.4e-07 28.8 2.5 3.2 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 EOO02529.1 - 9.2e-08 32.0 9.1 0.0016 18.1 0.3 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EOO02529.1 - 9.3e-08 31.6 1.1 0.0095 15.3 0.0 2.7 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EOO02529.1 - 6.2e-07 29.0 5.9 0.00012 21.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EOO02529.1 - 1.6e-06 27.1 13.2 8.8e-05 21.4 1.7 4.1 4 1 0 4 4 4 2 HI0933-like protein Thi4 PF01946.17 EOO02529.1 - 2.8e-06 26.8 3.4 9.5e-05 21.7 0.1 2.4 2 0 0 2 2 2 2 Thi4 family Lycopene_cycl PF05834.12 EOO02529.1 - 0.00017 20.8 0.8 0.017 14.2 0.0 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.6 EOO02529.1 - 0.00018 20.8 0.4 0.43 9.7 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EOO02529.1 - 0.0016 17.8 9.1 0.16 11.2 1.2 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.6 EOO02529.1 - 0.016 15.6 5.9 2.4 8.6 0.1 3.6 3 1 0 3 3 2 0 Putative NAD(P)-binding FMO-like PF00743.19 EOO02529.1 - 0.11 10.9 0.6 0.21 10.0 0.6 1.4 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.14 EOO02529.1 - 0.11 11.3 6.4 0.063 12.1 0.6 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 EOO02529.1 - 3.6 7.4 9.0 0.54 10.1 0.3 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_C14 PF00656.22 EOO02530.1 - 3.3e-63 214.0 0.0 4.2e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain HAD_SAK_1 PF10307.9 EOO02531.1 - 7.6e-77 257.7 0.0 1.1e-76 257.2 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Pkinase PF00069.25 EOO02532.1 - 6.1e-62 209.4 0.0 8.4e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO02532.1 - 4e-28 98.4 0.1 6.1e-28 97.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EOO02532.1 - 5.5e-05 22.3 0.2 8.1e-05 21.7 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EOO02532.1 - 0.00032 20.1 0.3 0.00053 19.4 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EOO02532.1 - 0.0071 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EOO02532.1 - 0.025 14.5 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EOO02532.1 - 0.056 12.5 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.11 EOO02532.1 - 0.093 13.0 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 S_100 PF01023.19 EOO02532.1 - 0.12 12.1 0.2 0.37 10.5 0.2 1.8 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain PH PF00169.29 EOO02533.1 - 5.5e-05 23.6 0.0 0.00014 22.3 0.0 1.7 1 0 0 1 1 1 1 PH domain Prominin PF05478.11 EOO02533.1 - 0.046 11.7 0.3 0.068 11.1 0.3 1.1 1 0 0 1 1 1 0 Prominin Gar1 PF04410.14 EOO02534.1 - 1.5e-39 135.3 0.0 1.9e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Cys_Met_Meta_PP PF01053.20 EOO02535.1 - 2.8e-36 124.9 0.0 3.4e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme APG9 PF04109.16 EOO02537.1 - 4.1e-127 425.1 6.3 2.3e-116 389.7 1.1 2.0 1 1 1 2 2 2 2 Autophagy protein Apg9 CHASE2 PF05226.11 EOO02537.1 - 0.15 11.7 0.1 0.21 11.3 0.1 1.1 1 0 0 1 1 1 0 CHASE2 domain RTA1 PF04479.13 EOO02538.1 - 1.5e-41 142.3 4.6 1.9e-41 141.9 4.6 1.2 1 0 0 1 1 1 1 RTA1 like protein Mito_carr PF00153.27 EOO02539.1 - 1.1e-46 156.7 2.7 6.2e-22 77.3 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EOO02539.1 - 0.00025 20.3 2.4 0.078 12.1 0.3 2.2 1 1 1 2 2 2 2 Gammaproteobacterial serine protease DUF1917 PF08939.10 EOO02540.1 - 2.2e-92 309.7 0.0 2.7e-92 309.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Histone PF00125.24 EOO02542.1 - 3.4e-21 76.0 2.1 4.3e-21 75.7 2.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EOO02542.1 - 4.2e-05 23.7 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EOO02542.1 - 0.00025 21.5 0.0 0.00043 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 EOO02542.1 - 0.037 13.7 0.1 0.09 12.4 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain FA_desaturase PF00487.24 EOO02543.1 - 3.1e-25 89.5 27.4 4.5e-25 88.9 27.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EOO02543.1 - 1.1e-10 41.5 0.0 2.1e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Xpo1 PF08389.12 EOO02544.1 - 1.5e-06 28.4 0.1 3.9e-05 23.7 0.0 3.1 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 EOO02544.1 - 0.00049 20.0 0.1 0.0069 16.3 0.1 3.0 3 1 1 4 4 4 1 Importin-beta N-terminal domain HEAT PF02985.22 EOO02544.1 - 0.23 11.8 1.4 37 4.9 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat MIF4G_like PF09088.11 EOO02545.1 - 0.22 11.3 0.1 0.35 10.6 0.1 1.2 1 0 0 1 1 1 0 MIF4G like Binary_toxB PF03495.14 EOO02545.1 - 0.38 11.0 1.5 57 4.0 0.1 3.6 3 1 1 4 4 4 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain MFS_1 PF07690.16 EOO02546.1 - 8.5e-32 110.4 28.4 8.5e-32 110.4 28.4 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily CDP-OH_P_transf PF01066.21 EOO02546.1 - 9.5e-12 45.5 0.1 9.5e-12 45.5 0.1 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Fungal_trans_2 PF11951.8 EOO02547.1 - 3.4e-06 26.1 0.9 6.4e-06 25.2 0.9 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Herpes_UL25 PF01499.16 EOO02547.1 - 0.086 11.4 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Peptidase_C12 PF01088.21 EOO02548.1 - 7.1e-62 208.9 0.0 1.1e-61 208.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EOO02548.1 - 0.039 13.9 0.1 0.61 10.0 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases N6-adenineMlase PF10237.9 EOO02549.1 - 3.9e-54 182.8 0.0 2e-53 180.5 0.0 2.0 2 0 0 2 2 2 1 Probable N6-adenine methyltransferase NmrA PF05368.13 EOO02549.1 - 2.5e-09 37.1 0.0 4.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO02549.1 - 4e-09 36.6 0.0 7.7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EOO02549.1 - 4e-07 29.3 0.0 6.9e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EOO02549.1 - 4.8e-07 29.5 0.0 8.3e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EOO02549.1 - 0.0042 16.2 0.1 0.1 11.7 0.0 2.7 2 1 0 2 2 2 1 RmlD substrate binding domain RXLR PF16810.5 EOO02549.1 - 0.046 14.2 0.1 3.6 8.0 0.0 2.3 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity adh_short_C2 PF13561.6 EOO02549.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase COQ9 PF08511.11 EOO02551.1 - 2e-32 110.8 0.0 3.1e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 COQ9 Whi5 PF08528.11 EOO02552.1 - 1.3e-09 37.5 0.1 2.4e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 Whi5 like LCAT PF02450.15 EOO02553.1 - 1e-105 354.2 0.1 1.2e-105 353.9 0.1 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EOO02553.1 - 0.02 15.5 0.1 0.045 14.3 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family BLACT_WH PF17778.1 EOO02554.1 - 2.6e-20 72.1 0.1 6.4e-20 70.9 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 EOO02554.1 - 1.4e-12 48.1 1.2 3.8e-10 40.1 1.2 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EOO02554.1 - 0.00078 19.0 0.0 0.0028 17.2 0.0 1.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain HemN_C PF06969.16 EOO02554.1 - 0.025 14.6 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 HemN C-terminal domain DUF2013 PF09431.10 EOO02555.1 - 2e-53 180.2 0.5 2e-53 180.2 0.5 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2013) N1221 PF07923.13 EOO02555.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 N1221-like protein W2 PF02020.18 EOO02556.1 - 1.9e-21 75.9 2.6 1.9e-21 75.9 2.6 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 EOO02556.1 - 2.8e-06 26.8 9.2 0.0042 16.7 2.2 3.1 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 EOO02556.1 - 3.2e-06 26.9 0.0 5.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 EOO02556.1 - 0.0012 17.1 3.2 0.0052 15.0 1.1 1.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EOO02556.1 - 0.028 14.2 5.4 0.48 10.2 0.5 3.0 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 EOO02556.1 - 0.029 14.7 0.0 0.087 13.2 0.0 1.9 1 0 0 1 1 1 0 MobA-like NTP transferase domain Fucokinase PF07959.12 EOO02556.1 - 0.16 10.9 0.5 0.32 9.9 0.5 1.5 1 0 0 1 1 1 0 L-fucokinase Cnn_1N PF07989.11 EOO02557.1 - 2.2e-26 91.8 4.6 2.2e-26 91.8 4.6 16.5 5 2 11 16 16 14 2 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 EOO02557.1 - 3.8e-21 75.4 1.0 3.8e-21 75.4 1.0 4.9 4 1 0 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF812 PF05667.11 EOO02557.1 - 4.1e-05 22.7 35.5 4.1e-05 22.7 35.5 7.5 2 1 4 7 7 5 1 Protein of unknown function (DUF812) Spc7 PF08317.11 EOO02557.1 - 0.00033 19.7 205.7 0.0017 17.3 20.2 10.0 3 2 8 11 11 11 8 Spc7 kinetochore protein MscS_porin PF12795.7 EOO02557.1 - 0.00081 19.0 18.6 0.00081 19.0 18.6 8.7 2 2 7 9 9 8 4 Mechanosensitive ion channel porin domain ABC_tran_CTD PF16326.5 EOO02557.1 - 0.0061 16.8 8.1 0.0061 16.8 8.1 16.2 5 5 11 16 16 15 4 ABC transporter C-terminal domain FlxA PF14282.6 EOO02557.1 - 0.0084 16.1 9.6 0.0084 16.1 9.6 12.4 5 1 8 13 13 13 2 FlxA-like protein DUF1664 PF07889.12 EOO02557.1 - 0.0093 16.0 5.9 0.0093 16.0 5.9 12.4 2 2 10 13 13 13 4 Protein of unknown function (DUF1664) DUF4200 PF13863.6 EOO02557.1 - 0.011 16.1 15.4 0.011 16.1 15.4 12.7 4 2 11 15 15 14 0 Domain of unknown function (DUF4200) DUF4495 PF14906.6 EOO02557.1 - 0.039 13.0 0.9 0.098 11.7 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) HMMR_N PF15905.5 EOO02557.1 - 8 5.8 183.3 1.6 8.2 17.8 7.9 2 2 6 8 8 8 0 Hyaluronan mediated motility receptor N-terminal SPX PF03105.19 EOO02558.1 - 1.9e-57 195.9 4.9 3e-57 195.3 4.9 1.3 1 0 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 EOO02558.1 - 5.2e-07 29.4 9.3 9.9e-07 28.5 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EOO02558.1 - 7.5e-07 28.9 10.9 1.7e-06 27.8 10.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EOO02558.1 - 1.2e-06 28.6 9.3 1.2e-06 28.6 9.3 2.0 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EOO02558.1 - 1.2e-06 28.2 11.8 2.5e-06 27.2 11.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EOO02558.1 - 7e-06 26.0 7.5 1.7e-05 24.8 7.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EOO02558.1 - 2.2e-05 24.7 12.1 4.7e-05 23.6 12.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EOO02558.1 - 0.00028 20.8 12.9 0.0017 18.3 13.2 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 EOO02558.1 - 0.024 14.4 5.5 0.024 14.4 5.5 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EOO02558.1 - 0.033 14.0 9.7 0.21 11.5 10.1 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EOO02558.1 - 0.048 13.7 3.8 0.09 12.8 3.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EOO02558.1 - 0.41 11.0 11.5 1.2 9.5 11.5 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_5 PF17121.5 EOO02558.1 - 0.73 9.8 7.9 2.9 7.8 7.9 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 EOO02558.1 - 1.3 8.9 6.2 2.7 7.9 6.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1644 PF07800.12 EOO02558.1 - 1.3 9.1 6.0 4 7.5 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) Zn-ribbon_8 PF09723.10 EOO02558.1 - 2.8 8.1 5.7 5.3 7.3 2.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_10 PF16685.5 EOO02558.1 - 5.8 7.1 10.3 11 6.2 9.9 1.6 1 1 0 1 1 1 0 zinc RING finger of MSL2 COG6 PF06419.11 EOO02559.1 - 2.5e-190 633.8 5.3 2.8e-190 633.7 5.3 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF3888 PF13027.6 EOO02560.1 - 0.021 15.2 0.1 0.03 14.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) DUF1835 PF08874.10 EOO02560.1 - 0.035 14.3 0.2 0.041 14.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) tRNA-synt_2b PF00587.25 EOO02561.1 - 8.5e-33 113.8 0.0 9.2e-31 107.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EOO02561.1 - 1.7e-20 73.0 0.4 3.4e-20 72.0 0.4 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EOO02561.1 - 1.6e-12 47.3 0.0 3.5e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EOO02561.1 - 8.3e-11 41.8 0.0 3e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 TGS domain SMC_N PF02463.19 EOO02562.1 - 3e-20 72.6 14.6 4.6e-19 68.7 14.6 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EOO02562.1 - 3.5e-18 66.8 7.1 3.5e-18 66.8 7.1 5.4 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 EOO02562.1 - 3.7e-10 40.1 0.7 3.7e-10 40.1 0.7 3.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EOO02562.1 - 0.00015 21.7 6.3 0.0023 17.8 0.5 3.2 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EOO02562.1 - 0.0011 18.7 0.0 0.003 17.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATG16 PF08614.11 EOO02562.1 - 0.0032 17.7 5.1 0.0032 17.7 5.1 6.7 3 2 4 7 7 7 3 Autophagy protein 16 (ATG16) SbcCD_C PF13558.6 EOO02562.1 - 0.0096 16.1 0.0 0.046 14.0 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF1664 PF07889.12 EOO02562.1 - 0.25 11.4 44.6 0.022 14.8 1.4 6.7 4 2 2 6 6 6 0 Protein of unknown function (DUF1664) HEM4 PF02602.15 EOO02563.1 - 7e-26 91.0 0.0 1.2e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TLD PF07534.16 EOO02563.1 - 2.5e-25 89.3 0.0 1.1e-13 51.6 0.0 2.3 2 0 0 2 2 2 2 TLD Rubella_E2 PF05749.11 EOO02563.1 - 0.074 12.5 4.6 1.7 8.1 0.2 2.8 2 1 0 2 2 2 0 Rubella membrane glycoprotein E2 Ytp1 PF10355.9 EOO02564.1 - 6.2e-122 406.1 7.2 9.5e-122 405.5 7.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EOO02564.1 - 2e-33 114.3 12.1 3e-33 113.8 5.2 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) KduI PF04962.12 EOO02564.1 - 0.039 13.3 0.1 0.062 12.6 0.1 1.2 1 0 0 1 1 1 0 KduI/IolB family Acetyltransf_1 PF00583.25 EOO02565.1 - 5.7e-20 71.7 0.0 7.5e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EOO02565.1 - 9.4e-11 41.8 0.0 1.4e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EOO02565.1 - 3.3e-10 39.8 0.0 5.3e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EOO02565.1 - 1.8e-09 37.9 0.0 2.5e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EOO02565.1 - 4.9e-07 30.5 0.0 5.7e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EOO02565.1 - 5.8e-06 26.0 0.0 7.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EOO02565.1 - 6.4e-05 23.0 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EOO02565.1 - 0.00056 20.0 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Aconitase PF00330.20 EOO02566.1 - 3e-149 498.0 0.0 3.8e-149 497.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EOO02566.1 - 4.3e-43 146.8 0.0 7.2e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain 2-oxoacid_dh PF00198.23 EOO02567.1 - 4.4e-79 265.2 0.1 7e-79 264.5 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EOO02567.1 - 3.3e-18 65.3 1.6 6.3e-18 64.4 1.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 EOO02567.1 - 0.0014 19.3 0.3 1.6 9.5 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EOO02567.1 - 0.0056 16.5 0.3 0.41 10.5 0.0 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like SAGA-Tad1 PF12767.7 EOO02567.1 - 3.2 7.4 7.3 2 8.1 5.2 1.9 2 1 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Vac14_Fig4_bd PF11916.8 EOO02568.1 - 8.5e-57 191.7 4.1 1.6e-56 190.8 4.1 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EOO02568.1 - 2.9e-08 34.2 3.3 0.023 15.3 0.1 4.4 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EOO02568.1 - 0.0026 18.2 1.3 1.1 9.9 0.0 3.9 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 EOO02568.1 - 3.5 8.2 5.0 29 5.3 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat R3H PF01424.22 EOO02569.1 - 2e-13 50.1 0.0 3.8e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 EOO02569.1 - 8e-12 44.9 2.4 1.6e-11 43.9 2.4 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EOO02569.1 - 1.1 9.4 7.7 0.048 13.8 1.0 2.3 3 0 0 3 3 3 0 G-patch domain Gaa1 PF04114.14 EOO02570.1 - 1.3e-138 463.1 0.0 1.6e-138 462.9 0.0 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component TMEM65 PF10507.9 EOO02570.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 65 Rsa3 PF14615.6 EOO02571.1 - 6.2e-22 76.9 0.3 7.7e-22 76.6 0.3 1.1 1 0 0 1 1 1 1 Ribosome-assembly protein 3 UCH PF00443.29 EOO02572.1 - 6.4e-50 170.0 1.2 8.2e-50 169.7 1.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EOO02572.1 - 4.2e-34 118.6 4.3 7.2e-34 117.8 4.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EOO02572.1 - 6.9e-05 23.1 0.2 6.9e-05 23.1 0.2 2.5 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf_C2H2_ZHX PF18387.1 EOO02572.1 - 0.078 12.6 0.1 0.078 12.6 0.1 2.4 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-CCHC_2 PF13696.6 EOO02572.1 - 5.8 6.8 8.2 8.7 6.3 0.7 3.1 3 0 0 3 3 3 0 Zinc knuckle SGT1 PF07093.11 EOO02573.1 - 1.7e-97 327.3 26.4 5.3e-87 292.6 0.0 2.0 1 1 1 2 2 2 2 SGT1 protein DUF1840 PF08895.11 EOO02573.1 - 0.22 11.9 4.0 0.63 10.4 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) PAS_9 PF13426.7 EOO02574.1 - 9.5e-27 93.3 0.1 6.9e-17 61.6 0.1 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 EOO02574.1 - 1.2e-19 70.4 0.0 7.8e-12 45.3 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 EOO02574.1 - 1.2e-15 57.5 0.0 9.2e-07 28.9 0.0 4.1 3 1 0 3 3 3 3 PAS fold GATA PF00320.27 EOO02574.1 - 4.1e-15 55.1 8.9 9.1e-15 54.0 8.9 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.6 EOO02574.1 - 9.7e-08 32.1 0.0 0.011 15.8 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 EOO02574.1 - 9.9e-07 29.0 0.0 0.088 13.1 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.11 EOO02574.1 - 7.8e-05 23.3 0.0 0.54 10.9 0.0 3.5 3 0 0 3 3 3 1 PAS fold PCI PF01399.27 EOO02576.1 - 7.5e-10 39.3 0.0 1.8e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 EOO02576.1 - 6.9e-06 25.5 2.5 1.4e-05 24.6 2.5 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix Dam PF05869.11 EOO02576.1 - 0.013 15.0 1.1 0.12 11.9 0.0 2.6 3 0 0 3 3 3 0 DNA N-6-adenine-methyltransferase (Dam) EMG1 PF03587.14 EOO02577.1 - 1.7e-79 266.0 0.0 2e-79 265.8 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase zf-C2H2_jaz PF12171.8 EOO02578.1 - 2e-10 40.7 0.2 3e-10 40.1 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EOO02578.1 - 0.057 14.3 0.3 0.15 13.0 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-SCNM1 PF15803.5 EOO02578.1 - 0.074 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 Transglut_core2 PF13369.6 EOO02579.1 - 2.2e-18 66.3 0.0 4.8e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.11 EOO02579.1 - 3.3e-14 53.2 0.6 1.8e-13 50.8 0.0 2.4 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like F-box-like PF12937.7 EOO02579.1 - 3e-06 27.0 1.2 6.2e-06 26.0 1.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EOO02579.1 - 0.0015 18.4 0.3 0.0032 17.3 0.3 1.6 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 EOO02579.1 - 0.25 11.9 2.2 0.25 11.9 0.3 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A TFIIA PF03153.13 EOO02580.1 - 0.0072 16.4 30.8 0.0077 16.3 30.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 EOO02580.1 - 1.3 7.1 14.3 1.6 6.9 14.3 1.0 1 0 0 1 1 1 0 Nop14-like family Endomucin PF07010.12 EOO02580.1 - 1.4 8.8 11.2 2.2 8.2 11.2 1.3 1 0 0 1 1 1 0 Endomucin CCSAP PF15748.5 EOO02580.1 - 4.6 7.3 16.7 6.4 6.9 16.7 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 EOO02580.1 - 5 6.9 14.0 9 6.0 14.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Complex1_LYR PF05347.15 EOO02581.1 - 1.1e-11 44.6 1.6 1.4e-11 44.2 1.6 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EOO02581.1 - 0.22 12.3 1.3 0.35 11.7 1.3 1.4 1 1 0 1 1 1 0 Complex1_LYR-like HSF_DNA-bind PF00447.17 EOO02582.1 - 2.5e-31 108.2 0.6 9.4e-31 106.3 0.5 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 EOO02582.1 - 3.4e-21 75.5 0.2 6.9e-21 74.5 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain DUF1635 PF07795.11 EOO02582.1 - 0.0051 16.7 0.4 0.0084 16.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) PK_C PF02887.16 EOO02582.1 - 0.018 15.2 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain TMCO5 PF14992.6 EOO02582.1 - 0.024 14.2 2.2 0.037 13.6 2.2 1.2 1 0 0 1 1 1 0 TMCO5 family CENP-H PF05837.12 EOO02582.1 - 0.033 14.6 2.1 0.065 13.7 2.1 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Ets PF00178.22 EOO02582.1 - 0.12 12.9 0.0 0.37 11.3 0.0 1.8 1 0 0 1 1 1 0 Ets-domain BRE1 PF08647.11 EOO02582.1 - 0.14 12.2 1.9 0.29 11.2 1.9 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Sec23_trunk PF04811.15 EOO02583.1 - 2.3e-70 236.9 0.0 3.5e-70 236.4 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EOO02583.1 - 2.4e-24 85.1 0.1 9.3e-24 83.2 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EOO02583.1 - 1.9e-17 63.8 0.0 4.1e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 EOO02583.1 - 2.4e-10 40.1 0.0 5.1e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DnaJ PF00226.31 EOO02585.1 - 5.7e-23 80.8 0.6 5.7e-23 80.8 0.6 2.3 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 EOO02585.1 - 7.4e-10 38.9 6.1 7.4e-10 38.9 6.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EOO02585.1 - 1.3e-09 38.1 8.6 5.2e-09 36.2 2.7 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EOO02585.1 - 2.1e-07 31.2 7.7 0.00023 21.4 2.0 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EOO02585.1 - 7.3e-06 26.4 3.9 0.038 14.8 0.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EOO02585.1 - 1.9e-05 24.9 5.7 0.04 14.4 0.6 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EOO02585.1 - 0.013 15.5 9.0 0.6 10.2 2.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Lact-deh-memb PF09330.11 EOO02585.1 - 0.083 12.2 3.7 0.13 11.6 3.7 1.2 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding zf-RING_11 PF17123.5 EOO02585.1 - 0.1 12.4 1.4 3.9 7.3 0.1 2.4 2 0 0 2 2 2 0 RING-like zinc finger Actin_micro PF17003.5 EOO02585.1 - 0.1 11.8 8.7 0.049 12.8 3.4 2.1 1 1 1 2 2 2 0 Putative actin-like family Rep_N PF08724.10 EOO02585.1 - 0.14 11.9 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Rep protein catalytic domain like CagZ PF09053.10 EOO02585.1 - 0.33 10.5 0.9 8.8 5.9 0.1 2.3 1 1 1 2 2 2 0 CagZ DUF678 PF05077.12 EOO02585.1 - 0.48 10.6 2.4 0.44 10.7 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF678) RRM_1 PF00076.22 EOO02586.1 - 1.2e-32 111.5 0.0 3.9e-16 58.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-grasp_2 PF08442.10 EOO02586.1 - 0.002 17.7 0.0 0.026 14.1 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain RRM_occluded PF16842.5 EOO02586.1 - 0.027 14.3 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 EOO02586.1 - 0.2 11.5 0.0 13 5.6 0.0 2.1 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain BRAP2 PF07576.12 EOO02586.1 - 0.25 11.6 0.0 3.7 7.8 0.0 2.1 2 0 0 2 2 2 0 BRCA1-associated protein 2 Acetyltransf_1 PF00583.25 EOO02587.1 - 9.8e-07 29.0 0.0 2.2e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EOO02587.1 - 0.00048 20.1 0.0 0.00069 19.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EOO02587.1 - 0.0012 19.2 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EOO02587.1 - 0.0018 18.4 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EOO02587.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase RRM_1 PF00076.22 EOO02588.1 - 1.2e-19 69.8 0.1 3.3e-12 46.0 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EOO02588.1 - 0.028 14.5 0.1 0.15 12.2 0.1 2.2 2 0 0 2 2 2 0 RNA recognition motif RRM_3 PF08777.11 EOO02588.1 - 2.1 8.4 12.3 1.4 9.0 8.7 2.5 2 1 1 3 3 3 0 RNA binding motif Chitin_synth_1 PF01644.17 EOO02589.1 - 1.5e-74 249.4 0.2 2.4e-74 248.7 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EOO02589.1 - 2.8e-29 100.9 0.0 5.4e-29 100.0 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EOO02589.1 - 9.7e-24 83.9 0.3 2e-17 63.0 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EOO02589.1 - 2.1e-07 31.1 0.9 2.1e-07 31.1 0.9 2.6 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Abhydrolase_9_N PF15420.6 EOO02589.1 - 4 7.4 7.7 2 8.4 1.9 2.5 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus FHA PF00498.26 EOO02590.1 - 3.3e-11 43.4 0.3 1.1e-10 41.7 0.0 2.0 2 0 0 2 2 2 1 FHA domain GlcV_C_terminal PF17847.1 EOO02590.1 - 0.3 11.6 0.7 0.73 10.3 0.0 2.0 2 0 0 2 2 2 0 Glucose ABC transporter C-terminal domain Peptidase_S10 PF00450.22 EOO02591.1 - 4.4e-84 283.3 0.0 5.8e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase HIF-1 PF11413.8 EOO02591.1 - 0.14 11.6 0.1 0.29 10.6 0.1 1.5 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 zf_CCCH_4 PF18345.1 EOO02592.1 - 4.7e-07 29.7 4.3 7.9e-07 28.9 4.3 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EOO02592.1 - 0.00019 21.1 2.8 0.00028 20.6 2.8 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EOO02592.1 - 0.00046 20.5 3.2 0.0007 20.0 3.2 1.3 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EOO02592.1 - 0.001 19.7 0.1 0.001 19.7 0.1 2.6 2 1 1 3 3 3 1 Torus domain zf-CCCH_3 PF15663.5 EOO02592.1 - 0.0019 18.4 0.3 0.0044 17.2 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH PF00642.24 EOO02592.1 - 0.0036 17.2 1.2 0.0062 16.4 1.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Glutaredoxin PF00462.24 EOO02593.1 - 3e-15 56.2 0.0 5.4e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Rad52_Rad22 PF04098.15 EOO02594.1 - 2.6e-61 206.0 0.0 3.5e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein SOBP PF15279.6 EOO02594.1 - 0.026 15.1 2.2 0.038 14.6 2.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein GST_N_3 PF13417.6 EOO02595.1 - 2.9e-11 43.6 0.0 4.8e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EOO02595.1 - 1.1e-10 41.6 0.0 1.8e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EOO02595.1 - 2e-07 31.2 0.0 3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EOO02595.1 - 1.6e-06 28.0 0.0 2.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EOO02595.1 - 4.2e-06 26.9 0.0 2.6e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EOO02595.1 - 0.023 14.9 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EOO02595.1 - 0.031 14.6 0.1 0.2 12.0 0.0 2.0 1 1 1 2 2 2 0 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 EOO02595.1 - 0.12 13.1 0.0 0.24 12.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain PRELI PF04707.14 EOO02596.1 - 1.2e-21 77.1 0.0 6.3e-18 65.1 0.0 2.1 1 1 1 2 2 2 2 PRELI-like family Pkinase PF00069.25 EOO02598.1 - 5.4e-07 29.2 0.0 1.2e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 EOO02598.1 - 3e-05 23.9 0.0 0.072 13.4 0.0 3.1 3 0 0 3 3 3 2 HEAT repeat Pkinase_Tyr PF07714.17 EOO02598.1 - 9.6e-05 21.8 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 EOO02598.1 - 0.00012 22.1 0.1 0.00024 21.2 0.1 1.4 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.6 EOO02598.1 - 0.044 13.1 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like HEAT_2 PF13646.6 EOO02598.1 - 0.14 12.6 0.0 1.8 9.0 0.0 2.5 2 1 1 3 3 3 0 HEAT repeats Aconitase PF00330.20 EOO02599.1 - 9e-146 486.5 0.0 1.1e-145 486.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EOO02599.1 - 1.2e-37 129.2 0.0 1.9e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Actin PF00022.19 EOO02600.1 - 5.4e-128 427.1 0.0 2.2e-127 425.0 0.0 1.7 1 1 0 1 1 1 1 Actin Transthyretin PF00576.21 EOO02601.1 - 7.6e-38 129.6 0.0 1e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 HIUase/Transthyretin family tRNA-synt_1b PF00579.25 EOO02602.1 - 8e-21 74.6 0.5 1.5e-20 73.7 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Aminotran_4 PF01063.19 EOO02603.1 - 1.1e-17 64.6 0.0 1.7e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV ArsA_ATPase PF02374.15 EOO02604.1 - 9e-113 376.5 0.0 1e-112 376.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EOO02604.1 - 2.6e-13 50.3 0.3 2.1e-11 44.1 0.0 3.0 2 2 0 2 2 2 1 AAA domain CbiA PF01656.23 EOO02604.1 - 1.2e-12 48.0 0.0 1.8e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EOO02604.1 - 7.4e-07 28.9 0.4 0.00022 20.8 0.1 2.4 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 EOO02604.1 - 6.3e-06 25.8 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 EOO02604.1 - 4.3e-05 23.2 0.5 0.0016 18.1 0.0 2.6 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 EOO02604.1 - 8.8e-05 22.1 0.0 0.00025 20.6 0.0 1.7 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 EOO02604.1 - 0.0094 16.4 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EOO02604.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EOO02604.1 - 0.09 11.9 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF3763 PF12592.8 EOO02604.1 - 0.13 12.4 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3763) AAA_18 PF13238.6 EOO02604.1 - 0.14 12.7 0.0 0.37 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EOO02604.1 - 0.17 11.3 0.0 0.49 9.8 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein RecG_N PF17190.4 EOO02604.1 - 1.6 9.5 5.0 0.67 10.7 1.1 2.3 2 1 0 2 2 2 0 RecG N-terminal helical domain Sec1 PF00995.23 EOO02605.1 - 1.9e-128 430.3 0.0 2.1e-128 430.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family G_glu_transpept PF01019.21 EOO02606.1 - 1.5e-147 492.5 0.0 1.7e-147 492.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase GHMP_kinases_N PF00288.26 EOO02608.1 - 9.7e-10 38.5 0.0 1.8e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EOO02608.1 - 4.1e-05 23.9 0.0 9.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal N_BRCA1_IG PF16158.5 EOO02609.1 - 4e-35 120.6 0.7 1.6e-34 118.7 0.0 2.4 3 0 0 3 3 3 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 EOO02609.1 - 6.6e-20 70.7 61.2 8e-07 28.8 10.0 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 EOO02609.1 - 0.0041 17.4 46.4 0.061 13.7 11.5 4.6 4 0 0 4 4 4 3 C1 domain Ebola_NP PF05505.12 EOO02609.1 - 0.038 12.3 0.6 0.079 11.3 0.6 1.4 1 0 0 1 1 1 0 Ebola nucleoprotein WD40 PF00400.32 EOO02610.1 - 3.9e-40 135.1 18.0 5.5e-10 39.7 0.0 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO02610.1 - 4.5e-14 52.5 0.7 0.013 15.8 0.0 4.7 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EOO02610.1 - 8.9e-10 38.0 0.4 0.26 10.2 0.0 4.6 1 1 3 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 EOO02610.1 - 1e-05 24.6 2.0 3.3e-05 23.0 0.1 2.6 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 EOO02610.1 - 1.8e-05 23.6 3.9 0.084 11.5 0.1 4.5 2 1 0 4 4 4 2 Nucleoporin Nup120/160 HPS3_N PF14761.6 EOO02610.1 - 0.0012 18.4 0.0 0.051 13.1 0.0 2.5 2 1 1 3 3 3 1 Hermansky-Pudlak syndrome 3 Frtz PF11768.8 EOO02610.1 - 0.0026 16.2 0.0 0.013 13.8 0.0 2.1 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 EOO02610.1 - 0.073 11.8 0.2 2.5 6.8 0.0 2.9 3 1 1 4 4 4 0 Nup133 N terminal like Hira PF07569.11 EOO02610.1 - 0.091 12.5 1.2 16 5.1 0.4 3.1 1 1 1 2 2 2 0 TUP1-like enhancer of split Btz PF09405.10 EOO02611.1 - 3.2e-26 92.1 1.8 3.2e-26 92.1 1.8 1.8 2 1 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding TFIIF_alpha PF05793.12 EOO02611.1 - 5.7 5.4 7.5 7.3 5.1 7.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Flavoprotein PF02441.19 EOO02613.1 - 1.2e-46 158.3 0.1 2.1e-46 157.5 0.1 1.4 1 1 0 1 1 1 1 Flavoprotein IFRD PF05004.13 EOO02614.1 - 3.9e-63 213.4 0.1 6.7e-63 212.6 0.1 1.3 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HET PF06985.11 EOO02615.1 - 1.2e-28 100.3 0.9 2e-28 99.6 0.9 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UPF0052 PF01933.18 EOO02616.1 - 1.1e-54 185.7 0.0 1.5e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Cut8 PF08559.10 EOO02617.1 - 7e-80 268.1 0.0 8.8e-80 267.8 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein AP_endonuc_2 PF01261.24 EOO02617.1 - 0.0095 15.4 0.0 0.031 13.7 0.1 1.8 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Asp PF00026.23 EOO02618.1 - 8.7e-60 202.8 2.5 1.2e-59 202.3 2.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EOO02618.1 - 9.5e-15 55.3 1.8 6.6e-10 39.5 0.0 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EOO02618.1 - 2.7e-05 24.7 3.9 0.072 13.7 0.2 3.4 2 1 1 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EOO02618.1 - 0.026 15.1 1.9 10 6.7 0.1 3.2 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease PCRF PF03462.18 EOO02619.1 - 1.2e-46 159.1 0.1 1.2e-46 159.1 0.1 1.8 3 0 0 3 3 3 1 PCRF domain RF-1 PF00472.20 EOO02619.1 - 1e-33 115.7 2.1 2.1e-33 114.7 2.1 1.5 1 0 0 1 1 1 1 RF-1 domain S_100 PF01023.19 EOO02619.1 - 0.024 14.3 0.9 0.4 10.4 0.0 2.4 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain DUF3602 PF12223.8 EOO02620.1 - 3.2e-21 75.7 11.6 1.7e-19 70.2 4.5 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) TPR_1 PF00515.28 EOO02621.1 - 1.1e-45 151.6 26.7 1.2e-06 28.0 0.1 11.2 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 EOO02621.1 - 3.6e-42 139.1 24.1 1.1e-05 25.1 0.2 11.3 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.6 EOO02621.1 - 1.3e-23 82.4 22.9 3.5e-06 26.6 0.0 9.3 7 3 3 10 10 9 6 TPR repeat TPR_16 PF13432.6 EOO02621.1 - 5.1e-23 81.4 12.9 2.2e-06 28.2 0.1 7.8 5 3 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 EOO02621.1 - 8.4e-22 75.5 28.7 0.00046 20.2 0.0 10.7 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_17 PF13431.6 EOO02621.1 - 1.1e-20 72.4 5.9 0.0003 21.0 0.0 8.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 EOO02621.1 - 1.6e-19 70.0 27.1 0.00099 19.4 0.7 8.5 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.6 EOO02621.1 - 1.6e-15 57.0 8.6 9.2e-06 25.7 0.1 6.1 6 2 2 8 8 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EOO02621.1 - 1.4e-14 54.3 19.4 1.1e-05 25.8 1.9 6.7 3 2 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 EOO02621.1 - 2.6e-12 46.5 14.6 0.029 15.2 0.8 8.4 4 3 6 10 10 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 EOO02621.1 - 3e-12 45.7 24.0 0.033 14.2 0.3 9.9 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_10 PF13374.6 EOO02621.1 - 5.3e-10 38.8 20.9 0.034 14.0 0.5 9.3 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EOO02621.1 - 4.1e-09 36.3 2.5 3.3e-08 33.3 2.5 2.3 1 1 0 1 1 1 1 MalT-like TPR region ANAPC3 PF12895.7 EOO02621.1 - 6.7e-08 32.7 12.9 0.12 12.6 0.3 5.5 2 2 4 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 EOO02621.1 - 9.8e-08 31.3 3.9 0.32 10.5 0.0 5.8 6 0 0 6 6 5 2 SHNi-TPR TPR_15 PF13429.6 EOO02621.1 - 3.1e-06 26.6 7.4 0.21 10.8 1.6 5.2 2 1 3 5 5 5 2 Tetratricopeptide repeat MAS20 PF02064.15 EOO02621.1 - 0.00046 20.3 12.3 0.098 12.8 1.6 4.5 5 0 0 5 5 5 1 MAS20 protein import receptor MIT PF04212.18 EOO02621.1 - 0.00059 19.9 13.3 4.1 7.5 0.0 6.7 6 0 0 6 6 6 1 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 EOO02621.1 - 0.00074 19.6 7.5 2.9 7.9 0.0 5.8 6 1 0 6 6 5 1 Domain of Unknown Function (DUF3856) TAF1_subA PF14929.6 EOO02621.1 - 0.007 15.8 1.4 0.073 12.5 1.4 2.2 1 1 0 1 1 1 1 TAF RNA Polymerase I subunit A SPO22 PF08631.10 EOO02621.1 - 0.0089 15.5 0.4 6.3 6.2 0.0 3.4 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like HrpB1_HrpK PF09613.10 EOO02621.1 - 0.02 14.5 0.7 0.17 11.6 0.4 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) preATP-grasp_3 PF18301.1 EOO02621.1 - 0.036 14.3 0.1 0.62 10.4 0.1 2.9 3 0 0 3 3 2 0 pre ATP-grasp 3 domain TPR_20 PF14561.6 EOO02621.1 - 0.043 14.2 7.8 0.79 10.1 0.1 4.7 6 0 0 6 6 4 0 Tetratricopeptide repeat VCX_VCY PF15231.6 EOO02621.1 - 0.081 13.6 7.4 0.17 12.5 7.4 1.5 1 0 0 1 1 1 0 Variable charge X/Y family Sel1 PF08238.12 EOO02621.1 - 0.1 13.3 6.7 1.8 9.4 0.1 4.1 4 0 0 4 4 3 0 Sel1 repeat ANAPC5 PF12862.7 EOO02621.1 - 0.17 12.0 6.5 9.5 6.4 0.0 4.8 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 5 DUF4810 PF16068.5 EOO02621.1 - 0.34 11.5 5.4 11 6.6 0.1 4.5 4 1 0 4 4 3 0 Domain of unknown function (DUF4810) HemY_N PF07219.13 EOO02621.1 - 0.47 10.7 6.3 31 4.8 1.0 5.0 4 2 2 6 6 6 0 HemY protein N-terminus TPR_6 PF13174.6 EOO02621.1 - 0.6 10.9 24.6 13 6.7 0.7 8.2 10 0 0 10 10 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 EOO02621.1 - 2 8.5 22.6 2.9 8.0 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.9 EOO02621.1 - 3.3 7.4 15.8 3 7.5 0.1 4.7 2 2 2 4 4 4 0 Tetratricopeptide repeat-like domain DUF5102 PF17104.5 EOO02621.1 - 4.3 7.3 7.3 1 9.3 3.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) DWNN PF08783.11 EOO02622.1 - 3.2e-31 107.4 0.0 6e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 EOO02622.1 - 7.6e-09 35.2 7.3 1.4e-08 34.4 7.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EOO02622.1 - 2.7e-05 24.0 1.8 4.8e-05 23.3 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EOO02622.1 - 0.0011 18.8 0.5 0.0027 17.6 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 EOO02622.1 - 0.0072 16.1 8.3 0.0072 16.1 8.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-DNL PF05180.12 EOO02622.1 - 0.023 14.6 0.2 0.059 13.3 0.2 1.7 1 0 0 1 1 1 0 DNL zinc finger U-box PF04564.15 EOO02622.1 - 0.026 14.7 0.0 0.077 13.2 0.0 1.8 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.8 EOO02622.1 - 0.052 13.4 3.1 0.14 12.0 3.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-CCHC_5 PF14787.6 EOO02622.1 - 0.16 11.7 0.7 0.38 10.5 0.7 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF3332 PF11810.8 EOO02622.1 - 1 9.0 4.7 0.2 11.3 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3332) zf-RING_UBOX PF13445.6 EOO02622.1 - 1.1 9.4 5.7 2.4 8.2 5.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EOO02622.1 - 1.8 8.5 7.8 4 7.4 7.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1388 PF07142.12 EOO02622.1 - 2.8 8.0 29.3 0.036 14.0 8.0 3.5 3 0 0 3 3 3 0 Repeat of unknown function (DUF1388) SOBP PF15279.6 EOO02622.1 - 5.5 7.5 41.0 0.81 10.2 29.6 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein zf-RING_5 PF14634.6 EOO02622.1 - 9.6 6.3 12.4 1.3 9.0 6.1 2.2 2 0 0 2 2 2 0 zinc-RING finger domain Syntaxin PF00804.25 EOO02623.1 - 2.2e-21 76.5 5.4 3.1e-21 76.0 5.4 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 EOO02623.1 - 4.7e-08 32.9 0.1 1.8e-07 31.1 0.1 2.1 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 EOO02623.1 - 0.0018 18.6 10.8 0.0063 16.9 4.3 2.3 2 0 0 2 2 2 1 Syntaxin-like protein MCU PF04678.13 EOO02623.1 - 0.11 12.6 6.2 0.56 10.3 6.2 2.2 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Allexi_40kDa PF05549.11 EOO02623.1 - 0.59 9.6 3.7 0.81 9.1 0.5 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein BLOC1_2 PF10046.9 EOO02623.1 - 0.78 10.1 0.0 0.78 10.1 0.0 3.1 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SGP PF17228.2 EOO02623.1 - 0.79 10.6 9.4 1.5 9.7 9.4 1.4 1 0 0 1 1 1 0 Sulphur globule protein CENP-F_leu_zip PF10473.9 EOO02623.1 - 1.2 9.2 9.6 0.63 10.1 1.2 3.4 3 1 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 EOO02623.1 - 6.3 7.0 7.0 8.5 6.6 0.2 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF1640 PF07798.11 EOO02624.1 - 1.4e-47 162.0 6.9 1.6e-47 161.8 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Cluap1 PF10234.9 EOO02624.1 - 0.013 14.9 6.9 0.016 14.6 6.9 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 GNAT_acetyltr_2 PF13718.6 EOO02624.1 - 0.053 12.9 0.6 0.094 12.1 0.6 1.6 1 1 0 1 1 1 0 GNAT acetyltransferase 2 HU-CCDC81_bac_2 PF18175.1 EOO02624.1 - 0.055 13.4 1.3 0.25 11.2 0.7 2.1 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 DUF1383 PF07134.11 EOO02624.1 - 0.095 11.8 1.0 0.14 11.3 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1383) Phage_GP20 PF06810.11 EOO02624.1 - 0.16 11.7 6.2 0.2 11.5 6.2 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 Lzipper-MIP1 PF14389.6 EOO02624.1 - 0.18 12.1 5.2 1.1 9.6 3.0 2.6 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Uso1_p115_C PF04871.13 EOO02624.1 - 1.3 9.4 10.3 1.6 9.1 2.0 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region BST2 PF16716.5 EOO02624.1 - 1.5 9.4 11.4 2.1 9.0 0.8 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 D-ser_dehydrat PF14031.6 EOO02625.1 - 8.5e-24 84.0 0.0 2.9e-23 82.3 0.0 2.0 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EOO02625.1 - 4.4e-11 42.8 0.3 7.2e-11 42.2 0.3 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF2807 PF10988.8 EOO02625.1 - 0.13 12.0 0.3 0.26 11.1 0.3 1.4 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain DUF489 PF04356.12 EOO02626.1 - 0.0029 17.6 1.0 0.0037 17.3 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF489) THOC7 PF05615.13 EOO02626.1 - 0.0064 16.8 6.3 0.0064 16.8 6.3 1.7 2 0 0 2 2 1 1 Tho complex subunit 7 Colicin_immun PF09204.10 EOO02626.1 - 0.046 14.3 0.6 0.12 13.0 0.1 1.9 1 1 1 2 2 2 0 Bacterial self-protective colicin-like immunity SKA1 PF07160.12 EOO02626.1 - 0.075 12.9 12.7 0.02 14.8 9.2 1.6 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 B-block_TFIIIC PF04182.12 EOO02626.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Baculo_PEP_C PF04513.12 EOO02626.1 - 0.13 12.3 0.1 0.36 10.9 0.0 1.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_60s PF00428.19 EOO02626.1 - 0.2 12.3 3.8 0.42 11.2 3.6 1.6 1 1 0 1 1 1 0 60s Acidic ribosomal protein Cep57_CLD_2 PF14197.6 EOO02626.1 - 0.31 11.2 9.4 0.71 10.0 2.1 3.2 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 Herpes_UL25 PF01499.16 EOO02626.1 - 0.74 8.3 7.2 0.98 7.9 7.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family YabA PF06156.13 EOO02626.1 - 1.1 10.0 5.9 10 6.8 0.5 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DUF1664 PF07889.12 EOO02626.1 - 1.3 9.1 4.1 1.2 9.2 2.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EOO02626.1 - 2.8 8.1 7.5 18 5.5 0.5 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 EOO02626.1 - 4.6 6.0 14.4 0.62 8.9 9.5 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Tho2 PF11262.8 EOO02626.1 - 4.8 6.3 10.4 0.32 10.2 5.0 1.6 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DivIC PF04977.15 EOO02626.1 - 6.1 6.7 8.0 11 5.8 1.0 2.9 1 1 1 2 2 2 0 Septum formation initiator Ribonuc_L-PSP PF01042.21 EOO02627.1 - 1e-38 132.1 0.1 1.1e-38 131.9 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DPPIV_N PF00930.21 EOO02628.1 - 1.9e-108 362.4 0.7 2.5e-108 362.0 0.7 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EOO02628.1 - 6.4e-53 179.4 1.7 1.5e-52 178.2 1.7 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EOO02628.1 - 1.1e-07 31.7 0.8 5.6e-05 22.9 0.4 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EOO02628.1 - 0.0028 18.3 0.6 0.041 14.5 0.6 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.12 EOO02628.1 - 0.0077 16.2 0.1 2.8 8.0 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DLH PF01738.18 EOO02628.1 - 0.083 12.4 0.1 0.67 9.5 0.1 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family KR PF08659.10 EOO02629.1 - 2e-28 99.5 0.1 5.7e-28 98.0 0.1 1.8 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EOO02629.1 - 1.2e-20 74.1 0.0 4.3e-20 72.3 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EOO02629.1 - 8.9e-20 72.1 0.0 2.3e-16 61.0 0.0 2.9 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EOO02629.1 - 4.6e-16 59.0 1.1 1.1e-14 54.5 0.1 3.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EOO02629.1 - 7e-13 48.7 0.0 8.5e-12 45.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO02629.1 - 7.7e-12 45.8 0.1 8.3e-11 42.5 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO02629.1 - 1.7e-09 38.2 0.0 4.5e-08 33.6 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO02629.1 - 1.5e-07 31.3 0.0 4.4e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EOO02629.1 - 4.2e-07 30.2 0.1 1.3e-06 28.6 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 EOO02629.1 - 1.4e-06 27.8 0.0 3.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.12 EOO02629.1 - 0.0036 17.2 0.1 0.0078 16.1 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_2 PF00891.18 EOO02629.1 - 0.0074 15.6 0.1 0.17 11.1 0.0 2.8 2 1 0 2 2 2 1 O-methyltransferase domain Glycos_transf_N PF04413.16 EOO02629.1 - 0.029 14.0 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Methyltransf_16 PF10294.9 EOO02629.1 - 0.055 13.2 0.0 0.16 11.7 0.0 1.7 1 1 0 1 1 1 0 Lysine methyltransferase NodS PF05401.11 EOO02629.1 - 0.099 12.2 0.0 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 Nodulation protein S (NodS) Glyco_hydro_47 PF01532.20 EOO02630.1 - 1.1e-71 242.1 0.0 1.3e-71 241.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RR_TM4-6 PF06459.12 EOO02631.1 - 1.3 8.8 21.3 1.4 8.7 21.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gln-synt_C PF00120.24 EOO02632.1 - 5.4e-17 61.8 0.0 9.1e-12 44.6 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EOO02632.1 - 2.3e-14 52.9 0.0 3.7e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Clathrin PF00637.20 EOO02633.1 - 2.5e-202 662.9 28.7 1.7e-31 109.0 2.0 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 EOO02633.1 - 2.4e-36 122.3 0.6 5.5e-06 26.4 0.0 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 EOO02633.1 - 1.1e-33 115.0 0.1 5.1e-33 112.8 0.1 2.3 1 0 0 1 1 1 1 Clathrin-H-link TPR_14 PF13428.6 EOO02633.1 - 2.2e-05 24.9 4.2 26 6.0 0.1 8.3 10 0 0 10 10 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 EOO02633.1 - 0.00043 20.1 5.7 2.6 8.3 0.1 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EOO02633.1 - 0.0014 18.9 1.6 31 5.0 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EOO02633.1 - 0.0024 18.0 5.6 0.98 9.8 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EOO02633.1 - 0.022 14.6 4.1 16 5.5 0.4 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EOO02633.1 - 0.051 13.7 0.6 1.6 8.9 0.1 3.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain VapB_antitoxin PF09957.9 EOO02633.1 - 0.073 13.0 0.1 2.1 8.3 0.0 2.9 2 0 0 2 2 2 0 Bacterial antitoxin of type II TA system, VapB Vps39_1 PF10366.9 EOO02633.1 - 0.1 12.9 3.0 38 4.6 0.0 5.8 7 1 0 7 7 7 0 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.17 EOO02633.1 - 0.3 11.3 8.1 51 4.3 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EOO02633.1 - 0.41 9.6 7.1 7.3 5.5 0.2 4.2 4 0 0 4 4 4 0 Coatomer WD associated region MFS_1 PF07690.16 EOO02634.1 - 2.4e-33 115.5 27.8 2.4e-33 115.5 27.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DHDPS PF00701.22 EOO02635.1 - 7.8e-42 143.0 0.0 9.9e-42 142.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GH131_N PF18271.1 EOO02636.1 - 6.3e-79 265.3 0.4 7.2e-79 265.1 0.4 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain FluMu_N PF17891.1 EOO02636.1 - 0.046 13.5 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain Abhydrolase_3 PF07859.13 EOO02637.1 - 4.2e-63 213.0 0.0 5.4e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EOO02637.1 - 1e-07 31.3 0.2 1.9e-07 30.4 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 EOO02637.1 - 4.9e-07 29.5 0.0 8.5e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 EOO02637.1 - 3.7e-05 22.8 0.0 6.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase DLH PF01738.18 EOO02637.1 - 0.039 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family TMEM239 PF15841.5 EOO02638.1 - 6.7 6.6 5.7 9 6.2 0.7 2.7 3 0 0 3 3 3 0 Transmembrane protein 239 family Glyco_hydro_79C PF16862.5 EOO02639.1 - 6e-17 62.4 0.1 1.2e-16 61.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain AA_permease_2 PF13520.6 EOO02640.1 - 4e-26 91.8 39.6 2.6e-20 72.7 26.8 2.0 1 1 1 2 2 2 2 Amino acid permease DUF2798 PF11391.8 EOO02640.1 - 1.4 9.0 17.0 1.6 8.8 3.5 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2798) HC2 PF07382.11 EOO02641.1 - 0.015 15.4 40.7 0.021 14.9 40.7 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 DUF3984 PF13136.6 EOO02641.1 - 0.022 14.2 0.6 0.024 14.1 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) SMYLE_N PF18615.1 EOO02641.1 - 0.16 11.5 9.8 0.18 11.3 9.8 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain PKcGMP_CC PF16808.5 EOO02642.1 - 0.14 12.0 1.4 0.23 11.3 0.4 1.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase YbjQ_1 PF01906.17 EOO02643.1 - 4.1e-29 101.3 0.3 4.8e-29 101.1 0.3 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding YobH PF13996.6 EOO02643.1 - 0.071 13.2 1.2 0.1 12.6 0.1 1.7 2 0 0 2 2 2 0 YobH-like protein FMN_dh PF01070.18 EOO02645.1 - 9.3e-86 288.0 0.0 6.3e-47 160.3 0.1 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Peptidase_M19 PF01244.21 EOO02645.1 - 0.0003 20.1 0.0 0.00085 18.6 0.0 1.6 2 0 0 2 2 2 1 Membrane dipeptidase (Peptidase family M19) DHO_dh PF01180.21 EOO02645.1 - 0.002 17.4 0.1 0.012 14.9 0.0 2.1 2 1 1 3 3 3 1 Dihydroorotate dehydrogenase IMPDH PF00478.25 EOO02645.1 - 0.0049 15.9 0.0 0.015 14.3 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EOO02645.1 - 0.012 15.1 0.4 0.84 9.1 0.0 2.8 1 1 1 2 2 2 0 Histidine biosynthesis protein Glu_synthase PF01645.17 EOO02645.1 - 0.065 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase NMO PF03060.15 EOO02645.1 - 0.11 11.9 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase Sugar_tr PF00083.24 EOO02646.1 - 9.7e-71 239.0 22.0 3.6e-57 194.2 13.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter DUF1593 PF07632.11 EOO02647.1 - 4.8e-97 324.4 0.0 6.6e-97 324.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 EOO02647.1 - 0.00031 19.7 0.1 0.00045 19.1 0.1 1.2 1 0 0 1 1 1 1 REJ domain Amidase PF01425.21 EOO02648.1 - 8.5e-17 61.2 0.0 8.2e-16 58.0 0.0 1.9 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 EOO02649.1 - 1.2e-24 86.9 34.4 5.2e-24 84.8 34.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 EOO02649.1 - 0.022 14.5 0.3 0.052 13.3 0.3 1.6 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) adh_short PF00106.25 EOO02650.1 - 4e-28 98.2 1.3 8.1e-27 94.0 0.2 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO02650.1 - 5.6e-15 55.5 0.1 7.7e-15 55.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO02650.1 - 2.2e-12 47.2 0.1 2.8e-12 46.9 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EOO02650.1 - 0.087 12.7 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Phosphoesterase PF04185.14 EOO02651.1 - 2.7e-59 201.1 0.8 3.7e-59 200.7 0.8 1.2 1 0 0 1 1 1 1 Phosphoesterase family Hydantoinase_B PF02538.14 EOO02652.1 - 5.9e-93 312.0 0.0 9.7e-66 222.2 0.0 2.6 2 1 1 3 3 3 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EOO02652.1 - 2.4e-88 296.2 7.7 1.1e-87 294.0 3.5 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EOO02652.1 - 2.3e-47 161.0 0.3 9.4e-45 152.5 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.20 EOO02652.1 - 0.019 14.5 1.3 2.6 7.4 0.2 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family SMP_LBD PF17047.5 EOO02653.1 - 8e-18 64.5 0.1 1.1e-17 64.0 0.1 1.2 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 EOO02653.1 - 5e-17 62.1 0.0 1.5e-11 44.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain Dioxygenase_C PF00775.21 EOO02654.1 - 7.6e-41 139.5 0.0 1e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EOO02654.1 - 3.3e-26 90.9 0.1 5e-26 90.4 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus SpaA PF17802.1 EOO02654.1 - 4.2e-05 23.8 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 Prealbumin-like fold domain CarboxypepD_reg PF13620.6 EOO02654.1 - 0.014 15.6 0.1 0.059 13.6 0.1 2.1 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Peptidase_U4 PF03419.13 EOO02655.1 - 0.0048 16.2 0.5 0.0048 16.2 0.5 1.9 1 1 1 2 2 2 1 Sporulation factor SpoIIGA TctB PF07331.11 EOO02655.1 - 0.017 15.4 5.7 0.54 10.5 0.0 2.6 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF4199 PF13858.6 EOO02655.1 - 0.042 14.2 8.1 0.15 12.4 8.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) GRA6 PF05084.13 EOO02655.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Erf4 PF10256.9 EOO02656.1 - 0.00055 20.0 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Aldo_ket_red PF00248.21 EOO02657.1 - 8.9e-14 51.4 0.0 1.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_1 PF00583.25 EOO02658.1 - 1.2e-06 28.7 0.0 1.7e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EOO02658.1 - 1.2e-05 26.0 0.0 2.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EOO02658.1 - 0.037 14.4 0.0 0.066 13.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EOO02658.1 - 0.089 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BCIP PF13862.6 EOO02658.1 - 0.17 11.7 0.4 0.34 10.7 0.0 1.5 1 1 1 2 2 2 0 p21-C-terminal region-binding protein HATPase_c PF02518.26 EOO02659.1 - 9.6e-29 100.2 0.0 2.4e-28 98.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EOO02659.1 - 1.4e-27 96.1 0.4 2.6e-27 95.2 0.4 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EOO02659.1 - 6.1e-15 55.0 0.0 1.4e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EOO02659.1 - 0.0024 18.2 0.2 0.22 11.9 0.0 2.8 2 0 0 2 2 2 1 HAMP domain Golgin_A5 PF09787.9 EOO02659.1 - 0.023 14.2 2.5 0.042 13.3 2.5 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 GRP PF07172.11 EOO02660.1 - 0.15 12.8 0.1 3.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Glycine rich protein family AIM24 PF01987.17 EOO02661.1 - 7.9e-50 169.4 0.1 9.4e-50 169.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 IDO PF01231.18 EOO02662.1 - 6.1e-28 97.8 0.0 7.7e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase RRP7 PF12923.7 EOO02663.1 - 4.5e-34 117.1 15.3 4.5e-34 117.1 15.3 1.6 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 EOO02663.1 - 1.7e-20 73.5 0.2 4e-20 72.2 0.0 1.7 3 0 0 3 3 3 1 Rrp7 RRM-like N-terminal domain DUF4741 PF15897.5 EOO02663.1 - 0.026 14.4 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4741) Usp PF00582.26 EOO02663.1 - 3.5 8.1 6.2 1.7 9.1 0.1 2.4 2 1 0 2 2 2 0 Universal stress protein family INO80_Ies4 PF08193.11 EOO02664.1 - 3.2e-82 276.2 21.0 3.9e-82 275.9 21.0 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 FUSC_2 PF13515.6 EOO02665.1 - 3e-05 24.1 0.0 6.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Fusaric acid resistance protein-like adh_short_C2 PF13561.6 EOO02666.1 - 3.1e-55 187.3 0.0 5.9e-55 186.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO02666.1 - 1.9e-49 167.8 0.2 2.6e-49 167.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO02666.1 - 3.3e-13 49.9 0.1 5.1e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO02666.1 - 0.072 12.5 0.1 0.27 10.7 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ORMDL PF04061.14 EOO02667.1 - 8.9e-60 200.4 3.6 1.1e-59 200.2 3.6 1.1 1 0 0 1 1 1 1 ORMDL family Pkinase PF00069.25 EOO02668.1 - 2e-62 211.0 0.0 2.3e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO02668.1 - 1.3e-36 126.2 0.0 2.1e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EOO02668.1 - 0.00014 20.8 0.0 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EOO02668.1 - 0.0015 17.9 0.0 0.0028 17.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EOO02668.1 - 0.0065 15.5 0.0 0.0088 15.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain A_deaminase PF00962.22 EOO02669.1 - 1.1e-22 80.8 0.0 2.3e-22 79.8 0.0 1.6 2 0 0 2 2 2 1 Adenosine/AMP deaminase Aldo_ket_red PF00248.21 EOO02670.1 - 1.2e-08 34.5 0.0 1.6e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MOSC PF03473.17 EOO02671.1 - 1.7e-12 47.5 0.0 4.3e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 MOSC domain NAD_binding_1 PF00175.21 EOO02671.1 - 2.4e-05 24.9 0.8 0.00028 21.5 0.0 2.6 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Fer2 PF00111.27 EOO02671.1 - 0.00037 20.4 0.1 0.00096 19.1 0.1 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 EOO02671.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 3-alpha domain GTP_EFTU_D2 PF03144.25 EOO02671.1 - 0.018 15.4 0.1 1.2 9.6 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu domain 2 Rib_recp_KP_reg PF05104.12 EOO02672.1 - 3.1 8.8 6.6 4.7 8.2 6.6 1.3 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region RepB-RCR_reg PF10723.9 EOO02673.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Replication regulatory protein RepB zf-CCHC PF00098.23 EOO02673.1 - 0.19 11.9 39.0 0.04 14.0 6.0 5.0 5 1 0 5 5 5 0 Zinc knuckle zf-CCHC_4 PF14392.6 EOO02673.1 - 0.25 11.1 22.5 0.49 10.2 0.2 3.7 4 0 0 4 4 4 0 Zinc knuckle YyzF PF14116.6 EOO02673.1 - 1 9.4 6.2 4.8 7.3 0.0 3.2 3 0 0 3 3 3 0 YyzF-like protein SDA1 PF05285.12 EOO02673.1 - 10 5.5 15.5 17 4.7 15.5 1.3 1 0 0 1 1 1 0 SDA1 Pex24p PF06398.11 EOO02674.1 - 5.2e-93 312.0 0.0 6.1e-93 311.7 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 EOO02674.1 - 0.0023 16.4 3.2 0.0025 16.3 1.3 1.7 1 1 0 2 2 2 1 Protein of unknown function (DUF3292) DUF4190 PF13828.6 EOO02674.1 - 0.11 12.3 1.1 0.26 11.1 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) GST_N_4 PF17172.4 EOO02675.1 - 4.3e-19 69.1 0.0 8.7e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EOO02675.1 - 2.9e-13 49.4 0.0 7.5e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EOO02675.1 - 7.8e-09 35.9 0.0 3e-08 34.0 0.0 2.0 2 1 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 EOO02675.1 - 0.00047 20.1 0.8 0.0009 19.2 0.8 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SAM35 PF10806.8 EOO02675.1 - 0.0019 18.5 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex PRP1_N PF06424.12 EOO02676.1 - 4.4e-45 153.7 9.5 4.9e-28 98.4 2.6 2.6 2 0 0 2 2 2 2 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 EOO02676.1 - 2.3e-29 101.7 9.6 9.8e-06 26.0 0.1 9.6 7 2 3 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.6 EOO02676.1 - 2e-27 93.5 31.9 0.0085 16.8 0.1 14.0 4 4 10 14 14 14 10 Tetratricopeptide repeat TPR_16 PF13432.6 EOO02676.1 - 1.9e-16 60.4 12.8 0.011 16.3 0.2 8.5 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 EOO02676.1 - 1.4e-14 52.9 6.7 0.57 10.4 0.0 10.3 10 1 1 11 11 10 3 Tetratricopeptide repeat NARP1 PF12569.8 EOO02676.1 - 1.1e-10 41.1 0.7 0.0091 15.0 0.0 5.7 4 1 2 6 6 6 3 NMDA receptor-regulated protein 1 TPR_17 PF13431.6 EOO02676.1 - 6.2e-09 35.6 1.4 11 6.6 0.0 9.1 9 1 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 EOO02676.1 - 2.1e-07 30.6 0.2 1.8 9.0 0.0 7.2 10 0 0 10 10 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 EOO02676.1 - 2.9e-07 30.0 24.3 0.006 15.8 1.2 6.5 3 2 4 7 7 7 3 Tetratricopeptide repeat NRDE-2 PF08424.10 EOO02676.1 - 1.2e-06 27.9 16.7 0.0076 15.4 0.1 4.9 4 1 1 5 5 5 3 NRDE-2, necessary for RNA interference TPR_1 PF00515.28 EOO02676.1 - 1.3e-06 28.0 0.0 1.2 9.1 0.0 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EOO02676.1 - 1.5e-05 25.0 9.9 0.00072 19.6 0.1 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EOO02676.1 - 0.00025 20.7 5.0 0.11 12.2 0.0 5.8 6 1 1 7 7 7 1 TPR repeat Suf PF05843.14 EOO02676.1 - 0.00025 21.1 0.0 6.1 6.7 0.0 4.5 4 1 1 5 5 5 1 Suppressor of forked protein (Suf) TPR_21 PF09976.9 EOO02676.1 - 0.00074 19.3 7.5 0.03 14.0 0.2 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 EOO02676.1 - 0.0059 17.2 3.6 41 5.1 0.0 7.1 9 0 0 9 9 5 0 Tetratricopeptide repeat DUF3808 PF10300.9 EOO02676.1 - 0.026 13.3 0.3 1.2 7.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3808) Wzy_C_2 PF11846.8 EOO02676.1 - 0.036 14.0 3.6 4.7 7.1 0.3 4.3 3 2 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal TPR_12 PF13424.6 EOO02676.1 - 0.049 13.9 5.4 46 4.4 0.4 6.6 7 1 1 8 8 7 0 Tetratricopeptide repeat 4HFCP_synth PF04476.13 EOO02676.1 - 0.053 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 4-HFC-P synthase ChAPs PF09295.10 EOO02676.1 - 0.3 10.0 2.2 0.68 8.9 0.1 2.5 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Maf1 PF09174.10 EOO02677.1 - 2.7e-63 213.2 0.0 3.9e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator PC4 PF02229.16 EOO02678.1 - 2.7e-23 81.3 0.1 4.3e-23 80.7 0.1 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) SabA_adhesion PF18304.1 EOO02678.1 - 0.0042 16.4 0.5 0.0076 15.5 0.2 1.3 1 1 0 1 1 1 1 SabA N-terminal extracellular adhesion domain DTHCT PF08070.11 EOO02678.1 - 2.7 8.8 13.9 7.9 7.3 2.7 2.3 2 0 0 2 2 2 0 DTHCT (NUC029) region YqfQ PF14181.6 EOO02678.1 - 2.9 8.1 8.9 0.13 12.4 1.9 1.9 1 1 0 2 2 2 0 YqfQ-like protein polyprenyl_synt PF00348.17 EOO02679.1 - 5.5e-64 215.7 0.0 6.7e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF1279 PF06916.13 EOO02680.1 - 1.7e-10 41.3 0.0 2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) MFS_1 PF07690.16 EOO02681.1 - 2.4e-34 118.8 35.1 2.9e-34 118.5 35.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EOO02681.1 - 9.5e-08 31.7 8.1 9.5e-08 31.7 8.1 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Syndecan PF01034.20 EOO02681.1 - 0.026 14.4 0.4 0.22 11.5 0.0 2.6 2 0 0 2 2 2 0 Syndecan domain PALP PF00291.25 EOO02682.1 - 1.9e-35 122.7 1.8 4.6e-35 121.5 1.8 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Lsm_interact PF05391.11 EOO02682.1 - 0.58 9.7 1.3 1.2 8.7 1.3 1.4 1 0 0 1 1 1 0 Lsm interaction motif Scytalone_dh PF02982.14 EOO02683.1 - 1e-61 207.4 0.4 1.3e-61 207.1 0.4 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 EOO02683.1 - 3.1e-05 24.1 0.5 4e-05 23.7 0.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF2555 PF10742.9 EOO02683.1 - 0.078 12.8 0.2 0.43 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) PP2C PF00481.21 EOO02684.1 - 5.8e-82 275.2 0.0 8.8e-82 274.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C MARVEL PF01284.23 EOO02685.1 - 1.8e-27 96.2 12.0 2.1e-27 95.9 12.0 1.0 1 0 0 1 1 1 1 Membrane-associating domain MpPF26 PF07666.11 EOO02685.1 - 0.067 13.3 5.4 1.4 9.0 2.9 2.8 2 1 0 2 2 2 0 M penetrans paralogue family 26 ADIP PF11559.8 EOO02686.1 - 9e-40 136.2 9.5 9e-40 136.2 9.5 2.3 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 EOO02686.1 - 0.035 13.6 7.4 0.14 11.6 7.4 2.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 PhoU PF01895.19 EOO02686.1 - 0.21 12.0 6.1 10 6.6 0.1 4.1 4 1 1 5 5 5 0 PhoU domain Spc7 PF08317.11 EOO02686.1 - 0.29 10.0 13.6 0.074 11.9 9.7 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 EOO02686.1 - 0.81 10.1 22.7 0.053 14.0 11.4 3.0 1 1 1 2 2 2 0 Fez1 Laminin_II PF06009.12 EOO02686.1 - 0.97 9.5 11.2 9 6.3 4.9 3.6 3 1 0 3 3 3 0 Laminin Domain II DegS PF05384.11 EOO02686.1 - 1 8.9 11.8 0.39 10.2 8.6 1.9 2 0 0 2 2 2 0 Sensor protein DegS TMPIT PF07851.13 EOO02686.1 - 1 8.5 2.4 2.2 7.5 2.4 1.5 1 0 0 1 1 1 0 TMPIT-like protein DUF948 PF06103.11 EOO02686.1 - 2.5 8.4 5.3 19 5.6 1.3 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DivIVA PF05103.13 EOO02686.1 - 4.5 7.4 16.7 1.4 9.0 7.3 2.8 3 0 0 3 3 3 0 DivIVA protein CLTH PF10607.9 EOO02687.1 - 2.2e-34 118.5 1.0 2.7e-34 118.2 0.3 1.5 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 EOO02687.1 - 9.9e-11 41.8 0.1 1.6e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 EOO02687.1 - 1.4e-06 28.0 0.9 5.6e-06 26.1 0.1 2.4 3 0 0 3 3 3 1 LisH SMC_ScpB PF04079.16 EOO02687.1 - 0.00086 19.0 0.0 0.0028 17.3 0.0 1.8 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB PAM2 PF07145.15 EOO02688.1 - 0.0069 16.0 0.1 0.022 14.4 0.1 1.8 1 0 0 1 1 1 1 Ataxin-2 C-terminal region MAGI_u5 PF16666.5 EOO02689.1 - 1.7 8.8 11.5 0.48 10.6 6.9 2.5 2 0 0 2 2 2 0 Unstructured region on MAGI CDC45 PF02724.14 EOO02689.1 - 7.7 4.7 10.6 12 4.1 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DAO PF01266.24 EOO02690.1 - 2.4e-39 135.9 0.5 2.9e-39 135.6 0.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EOO02690.1 - 0.0017 18.6 0.2 0.0046 17.2 0.2 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EOO02690.1 - 0.0017 17.7 0.0 0.004 16.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EOO02690.1 - 0.0071 15.5 0.4 0.06 12.4 0.4 2.1 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EOO02690.1 - 0.028 13.6 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 EOO02690.1 - 0.038 13.2 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EOO02690.1 - 0.073 12.3 0.0 0.31 10.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Oxysterol_BP PF01237.18 EOO02691.1 - 1.5e-109 366.3 0.0 2.7e-109 365.4 0.0 1.4 1 1 0 1 1 1 1 Oxysterol-binding protein SAT PF16073.5 EOO02692.1 - 3.5e-79 265.9 3.0 4.1e-79 265.7 0.5 2.2 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 EOO02692.1 - 9.2e-75 251.5 0.0 1.7e-74 250.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EOO02692.1 - 1.6e-42 146.2 0.0 4.3e-42 144.8 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EOO02692.1 - 2.5e-35 121.0 0.8 5.7e-35 119.9 0.8 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 EOO02692.1 - 1.5e-24 87.4 0.0 9.1e-24 84.8 0.0 2.3 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 EOO02692.1 - 1.6e-23 82.8 3.3 3.2e-11 43.4 0.3 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 EOO02692.1 - 2e-13 50.3 0.0 3.9e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 EOO02692.1 - 0.00041 19.8 0.2 0.0032 16.9 0.0 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 EOO02692.1 - 0.0022 18.4 0.0 0.0062 17.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Hydrolase_4 PF12146.8 EOO02692.1 - 0.035 13.4 0.0 0.36 10.0 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 AflR PF08493.10 EOO02692.1 - 0.14 11.6 2.3 0.39 10.2 2.3 1.7 1 0 0 1 1 1 0 Aflatoxin regulatory protein RCC1 PF00415.18 EOO02693.1 - 0.057 14.0 0.0 0.19 12.4 0.0 1.9 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat RNA_pol_3_Rpc31 PF11705.8 EOO02694.1 - 6.2 7.0 0.0 6.2 7.0 0.0 4.9 4 1 1 5 5 5 0 DNA-directed RNA polymerase III subunit Rpc31 Methyltransf_3 PF01596.17 EOO02696.1 - 1.2e-33 116.1 0.0 2.4e-33 115.1 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EOO02696.1 - 7.3e-11 43.0 0.1 4.3e-10 40.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EOO02696.1 - 1.5e-10 41.2 0.0 1.9e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EOO02696.1 - 3.1e-10 40.0 0.0 4.3e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO02696.1 - 5.2e-08 33.5 0.0 1.3e-07 32.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO02696.1 - 7.3e-05 23.3 0.1 0.00038 21.0 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EOO02696.1 - 0.0021 17.5 0.0 0.017 14.6 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.12 EOO02696.1 - 0.0089 16.8 0.0 0.028 15.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 EOO02696.1 - 0.029 14.0 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Usp PF00582.26 EOO02696.1 - 0.095 13.2 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Universal stress protein family Ubie_methyltran PF01209.18 EOO02696.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Apolipoprotein PF01442.18 EOO02697.1 - 0.016 15.1 1.5 0.047 13.6 1.5 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 EOO02697.1 - 0.14 12.2 4.8 0.25 11.4 4.8 1.4 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Borrelia_P83 PF05262.11 EOO02697.1 - 0.29 9.6 9.6 0.36 9.3 9.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein V-ATPase_G_2 PF16999.5 EOO02697.1 - 0.53 10.7 9.9 0.63 10.5 3.7 2.0 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 EOO02697.1 - 0.9 9.6 10.3 0.41 10.7 7.8 1.6 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Phasin PF05597.11 EOO02697.1 - 1 9.3 7.4 2.8 7.9 4.0 2.0 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Flot PF15975.5 EOO02697.1 - 6.9 6.9 14.6 0.84 9.8 6.7 2.1 1 1 1 2 2 2 0 Flotillin ETRAMP PF09716.10 EOO02697.1 - 7.5 6.7 8.1 23 5.1 4.1 2.5 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DNA_pol_E_B PF04042.16 EOO02698.1 - 2.9e-64 216.3 0.0 3.6e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Hydantoinase_B PF02538.14 EOO02699.1 - 4.5e-220 731.4 0.1 6.7e-220 730.9 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EOO02699.1 - 7.7e-104 347.0 1.1 7.7e-104 347.0 1.1 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EOO02699.1 - 1.1e-62 210.9 4.5 5.7e-62 208.6 0.4 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region SH2_2 PF14633.6 EOO02700.1 - 7.6e-87 290.2 0.0 7.6e-87 290.2 0.0 2.0 2 0 0 2 2 2 1 SH2 domain HTH_44 PF14641.6 EOO02700.1 - 1e-38 132.3 1.2 3.6e-38 130.5 1.2 2.0 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 EOO02700.1 - 5.2e-32 110.7 0.0 3.6e-31 108.0 0.0 2.4 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 EOO02700.1 - 9.6e-30 103.0 0.0 2.8e-29 101.5 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 EOO02700.1 - 1.5e-21 76.8 33.1 1.5e-21 76.8 33.1 6.7 4 1 4 8 8 8 1 Acidic N-terminal SPT6 S1 PF00575.23 EOO02700.1 - 1.1e-05 25.7 0.4 2.7e-05 24.4 0.4 1.8 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.24 EOO02700.1 - 1.2e-05 25.3 0.0 3.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 EOO02700.1 - 2e-05 25.4 1.9 2e-05 25.4 1.9 3.4 2 1 0 2 2 2 1 HHH domain HHH_3 PF12836.7 EOO02700.1 - 0.00058 20.1 0.0 0.0026 18.0 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif B12-binding PF02310.19 EOO02700.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain DUF92 PF01940.16 EOO02701.1 - 1.3e-71 240.7 0.6 5.7e-64 215.8 0.0 2.1 1 1 1 2 2 2 2 Integral membrane protein DUF92 MFS_1 PF07690.16 EOO02702.1 - 6.1e-33 114.2 26.8 9.4e-33 113.6 26.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ALMT PF11744.8 EOO02702.1 - 0.13 11.1 0.7 0.19 10.5 0.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter HAD_2 PF13419.6 EOO02703.1 - 1e-11 45.2 0.0 1e-06 29.0 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EOO02703.1 - 1.2e-07 32.3 0.2 0.0032 17.8 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EOO02703.1 - 1.5e-06 28.1 0.3 2.3e-06 27.6 0.3 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EOO02703.1 - 0.00029 21.3 0.0 0.0007 20.0 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 EOO02704.1 - 0.086 11.9 0.5 3 6.8 0.1 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain PNGaseA PF12222.8 EOO02705.1 - 8.7e-171 568.5 6.7 8.4e-169 562.0 6.7 2.0 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A APH PF01636.23 EOO02706.1 - 4.5e-10 39.9 0.9 3.3e-05 23.9 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 EOO02706.1 - 1e-09 38.2 0.0 1.3e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EOO02706.1 - 4e-08 32.9 0.0 2.4e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EOO02706.1 - 1.4e-06 27.8 0.0 1.8e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EOO02706.1 - 0.00031 20.4 0.0 0.0011 18.7 0.0 1.9 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EOO02706.1 - 0.068 11.9 0.0 0.092 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase CDC14 PF08045.11 EOO02707.1 - 3.3e-133 443.1 0.5 3.7e-133 443.0 0.5 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Cu-oxidase_2 PF07731.14 EOO02708.1 - 2.1e-43 147.3 5.0 9.2e-38 129.1 0.4 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EOO02708.1 - 2.4e-41 140.5 4.9 1e-38 132.0 0.3 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EOO02708.1 - 6.2e-29 101.2 0.2 4.9e-27 95.0 0.0 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.6 EOO02708.1 - 0.018 15.1 0.0 7.6 6.7 0.0 3.1 3 1 0 3 3 3 0 Cupredoxin-like domain Pkinase PF00069.25 EOO02709.1 - 5.6e-53 180.0 0.0 8.8e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO02709.1 - 3.2e-21 75.8 0.2 6.2e-21 74.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EOO02709.1 - 0.018 15.0 0.0 0.059 13.3 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 EOO02709.1 - 0.09 12.4 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 EOO02709.1 - 0.16 11.6 4.5 0.039 13.5 0.8 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase IBR PF01485.21 EOO02710.1 - 7.6e-06 26.1 21.3 2.4e-05 24.4 9.4 2.5 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain eIF-5_eIF-2B PF01873.17 EOO02711.1 - 3.9e-41 139.6 0.1 6e-41 139.0 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 SRP-alpha_N PF04086.13 EOO02711.1 - 3.1 7.6 8.0 4.1 7.2 8.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CsbD PF05532.12 EOO02712.1 - 1.8e-17 63.0 26.4 8.8e-10 38.3 6.3 3.1 2 1 1 3 3 3 3 CsbD-like AA_permease_2 PF13520.6 EOO02713.1 - 5.3e-51 173.8 36.8 7.1e-51 173.4 36.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EOO02713.1 - 1.8e-17 63.1 35.3 3.1e-17 62.3 35.3 1.3 1 1 0 1 1 1 1 Amino acid permease Clat_adaptor_s PF01217.20 EOO02714.1 - 4.3e-52 175.8 1.7 5.3e-52 175.5 1.7 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 EOO02714.1 - 0.033 14.9 0.1 0.062 14.1 0.1 1.5 1 0 0 1 1 1 0 Pullulanase N1-terminal domain CMD PF02627.20 EOO02715.1 - 6.2e-08 32.6 0.0 2.2e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family DUF3253 PF11625.8 EOO02715.1 - 0.052 13.8 0.2 0.16 12.2 0.0 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3253) PRMT5_C PF17286.2 EOO02715.1 - 0.15 11.9 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Guanylin PF02058.15 EOO02715.1 - 0.16 12.5 0.1 0.5 10.9 0.1 1.9 1 1 0 1 1 1 0 Guanylin precursor BAR PF03114.18 EOO02716.1 - 1.2e-68 231.3 8.4 1.5e-68 231.0 8.4 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EOO02716.1 - 5e-15 54.8 0.4 9.9e-15 53.9 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EOO02716.1 - 7.4e-14 51.3 0.1 1.2e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EOO02716.1 - 8.3e-11 41.4 0.5 4.8e-10 39.0 0.0 2.4 3 0 0 3 3 3 1 Variant SH3 domain TMPIT PF07851.13 EOO02716.1 - 0.13 11.5 5.9 2.2 7.5 0.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein CorA PF01544.18 EOO02716.1 - 5.8 6.1 7.6 25 4.0 3.7 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein F-box-like PF12937.7 EOO02717.1 - 2.4e-10 40.1 0.8 1.6e-09 37.5 0.1 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EOO02717.1 - 6.3e-10 38.7 0.1 2.5e-09 36.8 0.1 2.1 1 0 0 1 1 1 1 F-box domain Aminotran_5 PF00266.19 EOO02718.1 - 9e-93 311.2 0.0 1.1e-92 310.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EOO02718.1 - 6.8e-08 32.1 0.0 9.6e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EOO02718.1 - 4.4e-05 23.0 0.0 0.00019 20.9 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 EOO02718.1 - 0.019 13.7 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 EOO02718.1 - 0.053 12.0 0.0 0.082 11.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PPR_2 PF13041.6 EOO02719.1 - 0.00038 20.6 0.0 4.8 7.5 0.0 3.9 3 2 1 4 4 4 3 PPR repeat family PPR_3 PF13812.6 EOO02719.1 - 0.0032 17.5 0.0 2.1 8.5 0.0 2.8 2 0 0 2 2 2 2 Pentatricopeptide repeat domain KH_1 PF00013.29 EOO02719.1 - 0.016 15.0 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 KH domain PPR PF01535.20 EOO02719.1 - 0.092 13.0 0.1 2.2 8.7 0.0 2.9 3 0 0 3 3 3 0 PPR repeat Pkinase PF00069.25 EOO02721.1 - 1.7e-75 253.8 0.0 2.3e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO02721.1 - 1.1e-37 129.8 0.0 1.5e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.11 EOO02721.1 - 1.4e-15 57.1 0.2 2.6e-15 56.2 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) AdenylateSensor PF16579.5 EOO02721.1 - 4.5e-13 49.7 0.2 2.2e-12 47.5 0.2 2.1 1 1 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 EOO02721.1 - 1.5e-05 24.5 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EOO02721.1 - 0.00078 18.5 0.3 0.0019 17.2 0.3 1.7 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EOO02721.1 - 0.00089 18.9 0.2 0.0018 17.9 0.2 1.5 1 0 0 1 1 1 1 RIO1 family YukC PF10140.9 EOO02721.1 - 0.0041 16.0 0.1 0.0069 15.3 0.1 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 EOO02721.1 - 0.053 13.4 0.5 0.2 11.5 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EOO02721.1 - 0.084 12.2 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAD_binding_10 PF13460.6 EOO02722.1 - 2.2e-11 44.0 0.0 8.2e-10 38.9 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EOO02722.1 - 3.4e-10 39.9 0.0 1.5e-08 34.5 0.0 2.6 1 1 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EOO02722.1 - 0.00035 20.8 0.0 0.00078 19.7 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EOO02722.1 - 0.0074 16.5 0.4 0.012 15.9 0.4 1.3 1 0 0 1 1 1 1 TrkA-N domain DUF2855 PF11017.8 EOO02722.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Shikimate_DH PF01488.20 EOO02722.1 - 0.12 12.5 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L37ae PF01780.19 EOO02723.1 - 4.1e-31 106.9 5.8 4.9e-31 106.7 5.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 EOO02723.1 - 0.0021 18.2 2.4 0.0027 17.8 2.4 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 EOO02723.1 - 0.006 16.5 3.2 0.01 15.8 3.2 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.11 EOO02723.1 - 0.018 15.1 0.9 0.022 14.8 0.9 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Ima1_N PF09779.9 EOO02723.1 - 0.031 15.1 0.1 0.039 14.8 0.1 1.2 1 0 0 1 1 1 0 Ima1 N-terminal domain C1_2 PF03107.16 EOO02723.1 - 0.091 13.1 3.1 1.6 9.1 3.4 2.0 1 1 1 2 2 2 0 C1 domain A2L_zn_ribbon PF08792.10 EOO02723.1 - 0.19 11.5 4.7 3.9 7.3 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-BED PF02892.15 EOO02723.1 - 0.43 10.6 7.2 0.59 10.2 0.9 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 EOO02723.1 - 0.59 10.7 7.3 2.3 8.8 1.9 2.4 1 1 1 2 2 2 0 Zinc-finger double domain PHD PF00628.29 EOO02724.1 - 2e-09 37.2 5.0 2e-09 37.2 5.0 3.1 2 1 1 3 3 3 1 PHD-finger zf-RING_2 PF13639.6 EOO02724.1 - 1.3e-07 31.8 4.0 1.3e-07 31.8 4.0 3.7 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 EOO02724.1 - 3.5e-07 30.4 15.3 1.8e-06 28.1 4.6 3.5 3 0 0 3 3 3 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EOO02724.1 - 2.8e-05 23.9 4.4 2.8e-05 23.9 4.4 3.0 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EOO02724.1 - 4.7e-05 23.1 1.6 4.7e-05 23.1 1.6 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EOO02724.1 - 9.5e-05 22.3 3.5 9.5e-05 22.3 3.5 3.3 4 0 0 4 4 3 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EOO02724.1 - 0.00015 21.3 2.9 0.00015 21.3 2.9 2.7 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EOO02724.1 - 0.00018 21.3 2.1 0.00018 21.3 2.1 3.8 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 EOO02724.1 - 0.00037 20.0 1.6 0.00037 20.0 1.6 2.5 2 0 0 2 2 2 1 PHD-finger zf-ANAPC11 PF12861.7 EOO02724.1 - 0.00065 19.7 3.0 0.00065 19.7 3.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.12 EOO02724.1 - 0.0013 18.2 1.4 0.0025 17.2 0.9 1.8 1 1 0 1 1 1 1 Rtf2 RING-finger Prok-RING_1 PF14446.6 EOO02724.1 - 0.0026 17.6 3.3 0.0026 17.6 3.3 3.9 3 1 1 4 4 4 1 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.25 EOO02724.1 - 0.003 17.4 2.8 0.003 17.4 2.8 3.7 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-PHD-like PF15446.6 EOO02724.1 - 0.0041 16.8 5.5 0.009 15.6 0.5 2.7 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain zf-RING_UBOX PF13445.6 EOO02724.1 - 0.026 14.6 0.9 0.026 14.6 0.9 4.4 4 2 1 5 5 4 0 RING-type zinc-finger Rad50_zn_hook PF04423.14 EOO02724.1 - 0.42 10.5 2.5 8.4 6.3 0.0 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif RINGv PF12906.7 EOO02724.1 - 0.42 10.8 9.0 0.5 10.5 4.1 2.9 2 0 0 2 2 2 0 RING-variant domain Zf_RING PF16744.5 EOO02724.1 - 2 8.6 16.9 3.1 8.0 0.6 3.9 3 2 1 4 4 3 0 KIAA1045 RING finger Prim_Zn_Ribbon PF08273.12 EOO02724.1 - 2.2 8.6 7.7 3.3 8.1 0.1 3.2 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase DUF1644 PF07800.12 EOO02724.1 - 2.7 8.0 14.9 5.7 7.0 2.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1644) FANCL_C PF11793.8 EOO02724.1 - 2.8 8.2 8.8 0.22 11.7 1.0 2.6 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_9 PF13901.6 EOO02724.1 - 5.8 6.8 12.5 8.1 6.4 3.7 2.7 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHF5 PF03660.14 EOO02725.1 - 3.8e-52 174.9 10.4 4.2e-52 174.7 10.4 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EOO02725.1 - 0.65 7.8 7.6 0.68 7.7 7.6 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EOO02725.1 - 2.9 8.0 15.9 6.1 7.0 2.1 3.0 1 1 1 2 2 2 0 Double zinc ribbon Cpn60_TCP1 PF00118.24 EOO02726.1 - 5.4e-151 503.6 9.5 6.1e-151 503.4 9.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.11 EOO02726.1 - 0.031 13.9 0.1 0.1 12.1 0.1 1.9 1 0 0 1 1 1 0 Propionate catabolism activator TetR_C_14 PF17754.1 EOO02726.1 - 0.031 14.2 0.1 3.8 7.5 0.0 2.4 2 0 0 2 2 2 0 MftR C-terminal domain DUF2204 PF09970.9 EOO02726.1 - 0.047 13.3 2.4 17 5.0 0.0 3.5 3 1 0 3 3 3 0 Nucleotidyl transferase of unknown function (DUF2204) Flavoprotein PF02441.19 EOO02727.1 - 9e-23 80.8 0.1 1.1e-22 80.5 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein eIF-5_eIF-2B PF01873.17 EOO02728.1 - 2.4e-39 133.8 0.0 5.9e-39 132.6 0.0 1.7 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EOO02728.1 - 3.4e-23 81.6 0.4 1e-22 80.0 0.4 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Cwf_Cwc_15 PF04889.12 EOO02729.1 - 4e-89 298.6 20.9 4.5e-89 298.4 20.9 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 EOO02729.1 - 0.016 15.0 19.9 0.034 14.0 19.9 1.5 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing SDA1 PF05285.12 EOO02729.1 - 0.12 11.8 22.6 0.14 11.5 22.6 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EOO02729.1 - 1 7.5 21.4 1.1 7.4 21.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EOO02729.1 - 1 7.6 19.1 1.2 7.4 19.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3381 PF11861.8 EOO02729.1 - 1.4 8.7 17.6 2.5 7.9 17.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) ALMT PF11744.8 EOO02729.1 - 1.6 7.4 3.3 2.4 6.9 3.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Pet100 PF09803.9 EOO02729.1 - 2.8 8.5 5.6 5.3 7.6 4.6 1.9 2 0 0 2 2 2 0 Pet100 Hid1 PF12722.7 EOO02729.1 - 4.7 5.2 6.3 5.4 5.0 6.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ABC_membrane PF00664.23 EOO02730.1 - 1.7e-101 339.5 39.9 1.1e-53 182.7 16.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EOO02730.1 - 9.1e-69 230.3 0.3 3.8e-33 114.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EOO02730.1 - 8.4e-14 51.5 0.0 7.2e-05 22.3 0.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EOO02730.1 - 1.1e-07 31.5 1.1 0.0022 17.7 0.2 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EOO02730.1 - 2.7e-07 31.2 2.4 0.005 17.3 0.0 3.2 2 2 1 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EOO02730.1 - 1.8e-06 28.0 0.1 0.13 12.2 0.0 3.5 3 0 0 3 3 3 2 RsgA GTPase AAA PF00004.29 EOO02730.1 - 7.1e-06 26.5 1.9 4.1 7.8 0.1 4.6 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EOO02730.1 - 1.1e-05 25.3 0.1 0.1 12.3 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EOO02730.1 - 1.2e-05 25.6 1.3 0.039 14.2 0.0 3.6 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 EOO02730.1 - 5.1e-05 22.2 3.2 0.013 14.4 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 EOO02730.1 - 7.8e-05 22.5 0.3 0.44 10.2 0.0 3.7 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EOO02730.1 - 0.00047 20.1 1.0 1.2 8.9 0.0 3.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EOO02730.1 - 0.0015 18.2 1.9 0.29 10.7 0.1 3.2 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.14 EOO02730.1 - 0.0027 17.7 0.2 5.3 7.0 0.0 3.1 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EOO02730.1 - 0.0039 17.7 0.6 2.2 8.8 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 EOO02730.1 - 0.0048 17.4 3.7 1 9.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.20 EOO02730.1 - 0.0059 15.8 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_33 PF13671.6 EOO02730.1 - 0.0061 16.7 0.1 7.9 6.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 EOO02730.1 - 0.007 16.6 2.0 6.6 7.1 0.1 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 EOO02730.1 - 0.0077 16.2 0.1 0.045 13.7 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain DUF87 PF01935.17 EOO02730.1 - 0.008 16.3 4.8 0.61 10.1 0.1 3.4 3 0 0 3 3 3 1 Helicase HerA, central domain Zeta_toxin PF06414.12 EOO02730.1 - 0.0092 15.3 0.2 3.2 7.0 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_24 PF13479.6 EOO02730.1 - 0.012 15.3 0.1 0.9 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EOO02730.1 - 0.015 14.8 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 EOO02730.1 - 0.019 15.2 1.7 1.4 9.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 EOO02730.1 - 0.03 13.9 0.1 2.3 7.8 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF4381 PF14316.6 EOO02730.1 - 0.04 14.2 4.1 0.055 13.7 2.6 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4381) RNA_helicase PF00910.22 EOO02730.1 - 0.049 14.0 0.0 5.8 7.4 0.0 3.2 3 0 0 3 3 2 0 RNA helicase PRK PF00485.18 EOO02730.1 - 0.071 12.8 0.0 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 EOO02730.1 - 0.63 10.5 3.9 94 3.4 0.0 4.1 4 0 0 4 4 3 0 AAA domain Hydrolase_like PF13242.6 EOO02731.1 - 2.6e-05 24.2 0.0 5.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HTH_23 PF13384.6 EOO02731.1 - 0.061 13.1 0.0 7.6 6.5 0.0 2.7 2 0 0 2 2 2 0 Homeodomain-like domain VASt PF16016.5 EOO02732.1 - 2.5e-36 125.4 1.3 9.2e-36 123.6 1.3 2.1 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 EOO02732.1 - 3.3e-15 56.4 0.0 6.5e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EOO02732.1 - 9.1e-06 26.1 0.1 3.8e-05 24.2 0.1 2.2 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 EOO02732.1 - 0.033 14.0 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 GRAM domain BAR PF03114.18 EOO02732.1 - 0.048 13.3 0.2 0.11 12.1 0.2 1.5 1 0 0 1 1 1 0 BAR domain SIMPL PF04402.14 EOO02732.1 - 0.058 13.8 0.1 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF541) Thermopsin PF05317.11 EOO02732.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Thermopsin Abhydrolase_1 PF00561.20 EOO02733.1 - 2.7e-21 76.4 0.0 1.8e-15 57.3 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EOO02733.1 - 5.9e-12 46.7 0.7 8.1e-12 46.2 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EOO02733.1 - 3.5e-09 36.3 0.0 3.9e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 TetR_C_31 PF17940.1 EOO02733.1 - 0.024 14.9 0.0 0.57 10.4 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain EHN PF06441.12 EOO02733.1 - 0.044 14.2 0.4 0.15 12.4 0.0 2.1 3 0 0 3 3 3 0 Epoxide hydrolase N terminus VBS PF08913.10 EOO02733.1 - 0.14 12.6 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 Vinculin Binding Site MoaC PF01967.21 EOO02734.1 - 5.1e-26 91.4 0.1 6.4e-26 91.1 0.1 1.1 1 0 0 1 1 1 1 MoaC family SARAF PF06682.12 EOO02735.1 - 1.9e-76 257.9 0.0 2.3e-76 257.6 0.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Cript PF10235.9 EOO02737.1 - 2e-25 89.2 11.5 3.3e-25 88.5 11.5 1.3 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 EOO02737.1 - 0.018 15.3 9.5 0.018 15.3 9.5 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DZR PF12773.7 EOO02737.1 - 0.022 14.8 12.6 0.046 13.7 4.1 2.7 2 1 2 4 4 4 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 EOO02737.1 - 0.056 13.2 3.2 0.056 13.2 3.2 3.5 3 1 1 4 4 4 0 zinc-ribbon domain SARG PF15385.6 EOO02737.1 - 0.11 11.8 2.3 0.12 11.6 2.3 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein zinc_ribbon_15 PF17032.5 EOO02737.1 - 0.12 13.1 14.6 0.24 12.2 9.9 2.8 2 1 0 2 2 2 0 zinc-ribbon family Rhodanese_C PF12368.8 EOO02737.1 - 0.27 11.6 8.5 0.1 13.0 4.4 2.0 2 0 0 2 2 2 0 Rhodanase C-terminal CEBP_ZZ PF16366.5 EOO02737.1 - 1.1 9.6 9.2 0.27 11.5 5.4 1.8 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-RING_5 PF14634.6 EOO02737.1 - 2.5 8.2 13.5 36 4.4 10.6 3.0 2 1 1 3 3 3 0 zinc-RING finger domain AAA PF00004.29 EOO02738.1 - 1.7e-08 34.9 0.0 4e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EOO02738.1 - 0.0016 18.4 0.0 0.0047 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EOO02738.1 - 0.0048 17.3 0.0 0.016 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EOO02738.1 - 0.0088 16.3 0.2 0.04 14.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EOO02738.1 - 0.036 14.6 0.0 0.13 12.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 EOO02738.1 - 0.041 14.2 2.6 0.045 14.0 0.1 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain IstB_IS21 PF01695.17 EOO02738.1 - 0.084 12.6 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 EOO02738.1 - 5.2 7.3 6.4 0.98 9.7 0.1 3.0 3 1 1 4 4 4 0 AAA domain PH_10 PF15411.6 EOO02739.1 - 5.6e-29 100.9 0.2 9.3e-29 100.2 0.2 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 EOO02739.1 - 8.2e-14 52.2 0.0 1.2e-13 51.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EOO02739.1 - 4.1e-10 39.8 0.3 1.8e-09 37.7 0.1 2.2 2 1 0 2 2 2 1 von Willebrand factor type A domain EnY2 PF10163.9 EOO02740.1 - 0.007 16.7 0.0 0.023 15.1 0.0 1.8 2 0 0 2 2 2 1 Transcription factor e(y)2 MRP-L46 PF11788.8 EOO02741.1 - 5.3e-28 98.2 0.0 1e-27 97.2 0.0 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 EOO02741.1 - 0.00039 20.5 0.0 0.00085 19.4 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain ELO PF01151.18 EOO02742.1 - 7.2e-85 284.5 2.5 8.9e-85 284.2 2.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Docking PF08990.11 EOO02742.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Erythronolide synthase docking RseC_MucC PF04246.12 EOO02742.1 - 0.39 10.7 1.9 6.1 6.8 0.1 2.5 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC XPC-binding PF09280.11 EOO02743.1 - 2.6e-24 84.7 15.2 5.4e-24 83.7 15.2 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 EOO02743.1 - 8.4e-23 79.9 6.9 1.3e-13 50.5 0.5 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 EOO02743.1 - 3.4e-21 74.8 0.7 6.2e-21 73.9 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EOO02743.1 - 5.4e-09 35.7 0.9 9.6e-09 35.0 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 EOO02743.1 - 0.0019 17.9 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rib_recp_KP_reg PF05104.12 EOO02743.1 - 0.0028 18.7 10.3 0.0028 18.7 10.3 2.3 2 0 0 2 2 2 1 Ribosome receptor lysine/proline rich region MCM_N PF14551.6 EOO02743.1 - 0.018 15.6 0.1 0.044 14.4 0.1 1.6 1 0 0 1 1 1 0 MCM N-terminal domain Rad60-SLD_2 PF13881.6 EOO02743.1 - 0.024 14.7 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EOO02743.1 - 0.076 13.6 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 EOO02743.1 - 0.14 12.6 0.3 0.27 11.6 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain eIF-5a PF01287.20 EOO02743.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold WIYLD PF10440.9 EOO02743.1 - 0.2 11.5 0.3 2.7 7.8 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain TPR_16 PF13432.6 EOO02745.1 - 0.00084 19.9 10.7 0.039 14.6 5.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EOO02745.1 - 0.00098 19.1 0.1 0.2 11.9 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EOO02745.1 - 0.0029 18.3 4.8 0.0053 17.5 1.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EOO02745.1 - 0.0062 16.3 0.0 0.62 10.0 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EOO02745.1 - 0.11 13.1 0.7 0.11 13.1 0.7 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EOO02745.1 - 0.39 11.5 0.1 0.39 11.5 0.1 3.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Kazal_1 PF00050.21 EOO02746.1 - 0.041 13.9 0.1 0.084 12.9 0.1 1.4 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 EOO02746.1 - 0.14 12.3 0.4 0.14 12.3 0.4 2.0 3 0 0 3 3 3 0 Kazal-type serine protease inhibitor domain Ins_P5_2-kin PF06090.12 EOO02747.1 - 3.5e-41 141.7 0.0 6.4e-30 104.7 0.0 2.1 1 1 1 2 2 2 2 Inositol-pentakisphosphate 2-kinase B3 PF02362.21 EOO02747.1 - 0.2 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 B3 DNA binding domain AAA PF00004.29 EOO02748.1 - 8.9e-99 327.1 0.0 5.8e-48 162.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EOO02748.1 - 3.8e-25 87.4 4.8 7.4e-14 51.3 0.6 2.9 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EOO02748.1 - 8.1e-18 64.4 0.5 3e-17 62.5 0.5 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EOO02748.1 - 2.4e-14 53.4 0.0 3.2e-06 27.0 0.0 2.9 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EOO02748.1 - 3.2e-14 53.7 0.0 4.8e-05 23.8 0.0 4.8 3 2 1 4 4 4 2 AAA ATPase domain AAA_2 PF07724.14 EOO02748.1 - 4.9e-14 52.8 0.0 2.2e-07 31.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EOO02748.1 - 4e-12 46.3 0.4 3.5e-06 27.1 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EOO02748.1 - 7e-12 45.7 0.0 4.7e-05 23.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EOO02748.1 - 4.4e-10 40.0 0.3 0.0071 16.6 0.0 4.1 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 EOO02748.1 - 1.7e-09 37.4 0.1 0.0012 18.2 0.0 2.8 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 EOO02748.1 - 7.6e-08 32.0 0.0 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.17 EOO02748.1 - 1.4e-07 31.4 0.0 0.0092 15.7 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 EOO02748.1 - 1.6e-07 31.4 0.0 0.0083 16.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 EOO02748.1 - 2.2e-07 30.5 0.3 0.0067 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EOO02748.1 - 3.4e-07 30.9 0.0 0.05 14.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 EOO02748.1 - 5.5e-07 29.5 0.8 2.8e-06 27.2 0.2 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 EOO02748.1 - 8e-07 28.8 5.3 0.92 9.0 0.1 4.9 3 2 0 5 5 5 3 AAA domain RNA_helicase PF00910.22 EOO02748.1 - 9.8e-07 29.1 0.0 0.047 14.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ATPase PF06745.13 EOO02748.1 - 1.1e-06 28.2 0.2 0.25 10.6 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 EOO02748.1 - 1.5e-06 27.9 0.1 0.022 14.3 0.0 2.9 2 2 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 EOO02748.1 - 3.4e-06 26.9 0.0 0.084 12.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 EOO02748.1 - 4.1e-06 26.1 0.0 0.016 14.4 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 EOO02748.1 - 1.2e-05 24.5 0.0 0.07 12.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 EOO02748.1 - 1.3e-05 25.2 0.0 0.13 12.1 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein Sigma54_activat PF00158.26 EOO02748.1 - 1.3e-05 25.0 0.1 0.23 11.2 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 EOO02748.1 - 1.3e-05 25.5 0.1 0.15 12.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 EOO02748.1 - 1.9e-05 25.2 0.0 0.24 11.9 0.0 3.6 2 1 0 2 2 2 2 ABC transporter TsaE PF02367.17 EOO02748.1 - 7.8e-05 22.7 0.0 0.47 10.5 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 EOO02748.1 - 9.2e-05 22.9 0.0 0.6 10.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain PhoH PF02562.16 EOO02748.1 - 0.00017 21.1 0.3 0.5 9.8 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.12 EOO02748.1 - 0.0002 21.3 0.1 0.25 11.3 0.0 2.9 3 0 0 3 3 3 1 NACHT domain ResIII PF04851.15 EOO02748.1 - 0.00022 21.3 0.0 0.047 13.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 EOO02748.1 - 0.00025 20.9 0.0 0.69 9.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EOO02748.1 - 0.00031 20.6 0.1 1.2 8.9 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 EOO02748.1 - 0.00032 20.5 0.3 0.77 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 EOO02748.1 - 0.00032 20.7 0.0 1.9 8.3 0.0 3.6 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EOO02748.1 - 0.00098 19.5 0.4 5.9 7.2 0.0 3.7 3 1 1 4 4 3 0 AAA domain Sigma54_activ_2 PF14532.6 EOO02748.1 - 0.0014 18.7 0.0 0.52 10.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 EOO02748.1 - 0.0025 17.0 0.0 0.87 8.7 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain DUF2075 PF09848.9 EOO02748.1 - 0.0027 17.0 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) IPT PF01745.16 EOO02748.1 - 0.0046 16.4 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 1 Isopentenyl transferase NTPase_1 PF03266.15 EOO02748.1 - 0.018 14.9 0.8 7.2 6.5 0.0 3.8 4 0 0 4 4 3 0 NTPase KAP_NTPase PF07693.14 EOO02748.1 - 0.02 14.2 0.4 0.87 8.8 0.0 3.2 2 2 2 4 4 4 0 KAP family P-loop domain Viral_helicase1 PF01443.18 EOO02748.1 - 0.02 14.6 0.0 0.95 9.1 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 EOO02748.1 - 0.03 13.6 0.5 11 5.3 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin Zot PF05707.12 EOO02748.1 - 0.038 13.6 0.0 2.4 7.7 0.0 3.1 3 1 0 3 3 2 0 Zonular occludens toxin (Zot) Cytidylate_kin PF02224.18 EOO02748.1 - 0.042 13.6 0.0 6.8 6.4 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase UFD1 PF03152.14 EOO02748.1 - 0.043 13.3 0.0 0.2 11.1 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 AFG1_ATPase PF03969.16 EOO02748.1 - 0.063 12.2 0.0 7.2 5.4 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase AAA_6 PF12774.7 EOO02748.1 - 0.16 10.9 0.3 7.7 5.4 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region HRI1 PF16815.5 EOO02749.1 - 5.7e-50 170.2 0.0 6.6e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Protein HRI1 Nucleoside_tran PF01733.18 EOO02750.1 - 3.4e-39 135.1 1.5 1.8e-38 132.6 1.5 2.1 1 1 0 1 1 1 1 Nucleoside transporter DUF3433 PF11915.8 EOO02750.1 - 0.63 10.5 10.5 0.11 13.0 1.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3433) Catalase PF00199.19 EOO02751.1 - 3.1e-76 257.0 0.0 3.9e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 EOO02751.1 - 2e-48 163.9 0.1 3.2e-48 163.2 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 EOO02751.1 - 1e-19 70.5 0.0 1.6e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive LINES_C PF14695.6 EOO02751.1 - 0.13 11.7 0.3 0.25 10.8 0.3 1.4 1 0 0 1 1 1 0 Lines C-terminus PBP PF01161.20 EOO02752.1 - 9.4e-17 61.6 0.0 1.3e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Thiamine_BP PF01910.17 EOO02753.1 - 2.2e-32 110.8 0.3 2.5e-32 110.7 0.3 1.0 1 0 0 1 1 1 1 Thiamine-binding protein SYF2 PF08231.12 EOO02754.1 - 4.2e-55 186.5 19.1 4.2e-55 186.5 19.1 2.4 2 1 0 2 2 2 1 SYF2 splicing factor Adenylsucc_synt PF00709.21 EOO02754.1 - 0.044 12.7 0.3 0.044 12.7 0.3 2.2 2 1 1 3 3 3 0 Adenylosuccinate synthetase Mob_synth_C PF06463.13 EOO02755.1 - 3.9e-38 130.3 0.1 6.8e-37 126.3 0.0 2.2 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EOO02755.1 - 3.3e-24 86.1 0.0 5.9e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EOO02755.1 - 8.5e-06 26.1 0.0 0.00014 22.2 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EOO02755.1 - 0.071 13.2 1.2 0.3 11.2 0.0 2.6 4 0 0 4 4 4 0 4Fe-4S single cluster domain Holin_BhlA PF10960.8 EOO02755.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 BhlA holin family RRM_1 PF00076.22 EOO02756.1 - 0.00025 20.8 0.0 0.00045 20.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3074 PF11274.8 EOO02757.1 - 7.8e-58 195.5 4.2 8.5e-58 195.4 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3074) LMBR1 PF04791.16 EOO02757.1 - 9.7 5.0 7.5 15 4.3 7.5 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein AA_permease PF00324.21 EOO02760.1 - 4e-142 474.2 35.6 4.9e-142 473.9 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EOO02760.1 - 1.1e-43 149.7 39.1 1.4e-43 149.3 39.1 1.0 1 0 0 1 1 1 1 Amino acid permease RNase_PH PF01138.21 EOO02761.1 - 1.3e-23 83.9 0.0 3e-23 82.8 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EOO02761.1 - 1.3e-06 28.3 0.0 2.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Asp-B-Hydro_N PF05279.11 EOO02762.1 - 1.2 9.1 21.2 2.1 8.4 21.2 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Utp14 PF04615.13 EOO02762.1 - 1.6 7.2 42.6 0.078 11.5 36.1 1.9 2 0 0 2 2 2 0 Utp14 protein Red1 PF07964.11 EOO02762.1 - 3.2 5.9 32.8 5.1 5.2 32.8 1.3 1 0 0 1 1 1 0 Rec10 / Red1 Hid1 PF12722.7 EOO02762.1 - 6.1 4.8 21.4 9.6 4.2 21.4 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein U3_snoRNA_assoc PF08297.11 EOO02763.1 - 5.2e-18 65.5 1.3 5.2e-18 65.5 1.3 4.8 3 2 0 3 3 3 1 U3 snoRNA associated DUF1749 PF08538.10 EOO02764.1 - 1.6e-68 231.0 0.0 2.1e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 EOO02764.1 - 6.7e-05 23.6 0.0 9.9e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EOO02764.1 - 0.0069 16.1 0.0 0.0095 15.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EOO02764.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EOO02764.1 - 0.025 14.5 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase LCAT PF02450.15 EOO02764.1 - 0.08 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase YEATS PF03366.16 EOO02765.1 - 8e-31 105.9 0.3 1.2e-30 105.3 0.3 1.3 1 0 0 1 1 1 1 YEATS family Pyr_redox_2 PF07992.14 EOO02766.1 - 7.2e-54 183.0 0.1 8.8e-54 182.7 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EOO02766.1 - 6.7e-12 45.8 0.0 3.6e-10 40.3 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EOO02766.1 - 9.3e-05 21.8 1.0 0.043 13.1 0.2 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase PhoLip_ATPase_C PF16212.5 EOO02767.1 - 7e-82 274.9 15.1 7e-82 274.9 15.1 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EOO02767.1 - 1.4e-26 91.9 6.5 3.8e-26 90.6 6.5 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EOO02767.1 - 4.9e-11 43.3 2.3 4.7e-06 27.0 0.4 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EOO02767.1 - 1e-10 41.5 0.0 4.9e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EOO02767.1 - 1.5e-08 34.3 0.0 3.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EOO02767.1 - 0.001 18.9 0.0 0.0076 16.0 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Imm49 PF15575.6 EOO02767.1 - 0.067 12.9 0.2 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 Immunity protein 49 DNA_III_psi PF03603.13 EOO02767.1 - 0.085 13.1 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III psi subunit Mt_ATP-synt_B PF05405.14 EOO02767.1 - 0.12 12.0 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Pinin_SDK_memA PF04696.13 EOO02768.1 - 4.2e-35 120.6 18.2 4.2e-35 120.6 18.2 2.0 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Acetyltransf_1 PF00583.25 EOO02769.1 - 1.5e-09 38.1 0.0 3.5e-09 36.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EOO02769.1 - 2.5e-09 37.4 0.0 1.4e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EOO02769.1 - 5e-08 32.9 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EOO02769.1 - 9.7e-06 25.6 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EOO02769.1 - 8.9e-05 22.4 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EOO02769.1 - 0.00013 22.1 0.0 0.25 11.4 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain GMC_oxred_N PF00732.19 EOO02770.1 - 4.3e-47 160.9 0.3 6e-47 160.4 0.3 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EOO02770.1 - 1.2e-25 90.7 0.5 4.4e-25 88.9 0.0 2.2 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EOO02770.1 - 8.6e-08 31.7 4.1 2.2e-07 30.3 4.1 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EOO02770.1 - 6e-07 29.0 0.1 3.4e-05 23.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EOO02770.1 - 4.2e-05 23.7 2.6 6.7e-05 23.0 1.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EOO02770.1 - 4.2e-05 23.3 2.0 0.024 14.2 0.6 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EOO02770.1 - 0.00011 21.6 0.3 0.0002 20.7 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EOO02770.1 - 0.00061 19.1 2.9 0.022 14.0 0.3 2.8 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.14 EOO02770.1 - 0.0022 16.8 0.8 0.0052 15.5 0.4 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EOO02770.1 - 0.041 13.2 1.3 0.058 12.7 0.8 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 EOO02770.1 - 0.042 13.4 2.2 0.066 12.8 2.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 EOO02770.1 - 0.07 13.7 0.2 0.17 12.5 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EOO02770.1 - 0.12 11.6 0.2 2.6 7.2 0.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EOO02770.1 - 0.22 10.6 0.1 1.5 7.8 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 EOO02770.1 - 0.22 11.4 0.1 0.36 10.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF155 PF02582.14 EOO02771.1 - 2.5e-51 174.2 0.3 3.7e-51 173.7 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 NAD_binding_4 PF07993.12 EOO02772.1 - 0.0082 15.3 0.0 0.0099 15.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein HMG_box PF00505.19 EOO02773.1 - 2.6e-09 37.3 3.9 2.6e-09 37.3 3.9 2.5 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EOO02773.1 - 0.0011 19.6 3.8 0.0011 19.6 3.8 3.0 2 1 1 3 3 3 1 HMG-box domain CCDC106 PF15794.5 EOO02773.1 - 3.9 7.1 12.2 0.029 14.1 1.4 2.5 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 106 DUF4407 PF14362.6 EOO02773.1 - 5.3 6.3 11.3 2.5 7.4 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ATP-synt_E PF05680.12 EOO02773.1 - 6.6 7.1 11.5 28 5.1 6.8 2.4 2 0 0 2 2 2 0 ATP synthase E chain DUF1682 PF07946.14 EOO02774.1 - 2.4e-111 372.0 4.1 2.8e-111 371.8 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF2985 PF11204.8 EOO02774.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) Glyco_hydro_35 PF01301.19 EOO02775.1 - 1.2e-75 255.0 3.8 2.5e-75 254.1 3.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 EOO02775.1 - 3.8e-58 195.0 0.7 1.4e-33 115.9 0.0 3.0 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 EOO02775.1 - 4.2e-53 179.8 5.5 4.2e-53 179.8 5.5 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 EOO02775.1 - 1.4e-23 82.2 0.4 7.3e-23 79.9 0.2 2.3 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 EOO02775.1 - 3.2e-06 26.7 0.0 0.0024 17.3 0.0 2.8 2 1 1 3 3 3 2 Beta-galactosidase Cellulase PF00150.18 EOO02775.1 - 0.012 15.1 0.3 0.19 11.1 0.1 2.7 2 1 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) UPF1_Zn_bind PF09416.10 EOO02776.1 - 1.8e-71 239.0 2.6 1.3e-70 236.2 0.5 2.4 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 EOO02776.1 - 1.4e-60 204.3 0.0 3.4e-60 203.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EOO02776.1 - 1.1e-54 186.0 4.2 6.9e-31 108.0 0.3 2.4 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 EOO02776.1 - 4.8e-33 113.3 0.0 9.7e-33 112.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EOO02776.1 - 7.5e-13 48.6 0.4 1e-11 44.9 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EOO02776.1 - 1.9e-10 41.3 0.3 8.8e-10 39.1 0.3 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EOO02776.1 - 3.4e-06 27.2 0.0 6.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EOO02776.1 - 2.1e-05 24.5 0.0 4.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 EOO02776.1 - 8.6e-05 22.4 0.1 0.91 9.2 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EOO02776.1 - 0.00018 20.9 0.2 0.004 16.4 0.1 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 EOO02776.1 - 0.00028 20.5 0.1 0.0071 15.9 0.1 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 EOO02776.1 - 0.00028 20.2 0.0 0.19 10.8 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase DEAD PF00270.29 EOO02776.1 - 0.0018 18.1 0.1 0.0037 17.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.22 EOO02776.1 - 0.0038 16.9 0.1 0.0085 15.7 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ATPase PF06745.13 EOO02776.1 - 0.005 16.2 0.0 0.025 13.9 0.0 1.9 2 0 0 2 2 2 1 KaiC AAA_10 PF12846.7 EOO02776.1 - 0.013 14.5 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 EOO02776.1 - 0.016 15.5 0.0 0.062 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EOO02776.1 - 0.05 13.0 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein DUF4592 PF15262.6 EOO02777.1 - 0.61 10.8 5.3 1.1 10.0 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) Pro-kuma_activ PF09286.11 EOO02778.1 - 2.7e-39 134.7 0.2 6.3e-39 133.5 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EOO02778.1 - 0.0038 16.5 0.0 0.014 14.7 0.0 1.8 1 1 0 1 1 1 1 Subtilase family AhpC-TSA_2 PF13911.6 EOO02779.1 - 5.3e-18 65.2 0.0 1.5e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Brix PF04427.18 EOO02780.1 - 6.5e-29 101.4 0.0 8.3e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain Aminotran_4 PF01063.19 EOO02781.1 - 1.6e-26 93.6 0.0 2.1e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DEK_C PF08766.11 EOO02781.1 - 0.07 13.1 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 DEK C terminal domain T4_Rnl2_C PF18043.1 EOO02782.1 - 0.04 14.1 0.1 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 T4 RNA ligase 2 C-terminal TSNAXIP1_N PF15739.5 EOO02782.1 - 0.26 11.7 1.2 0.61 10.5 0.1 2.2 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus MMS1_N PF10433.9 EOO02783.1 - 1.8e-158 528.2 0.0 3.7e-158 527.2 0.0 1.4 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EOO02783.1 - 2.7e-100 335.8 0.0 5.7e-100 334.8 0.0 1.6 2 0 0 2 2 2 1 CPSF A subunit region Pox_Ag35 PF03286.14 EOO02784.1 - 1.1 9.0 5.9 3.2 7.5 5.9 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFIIF_alpha PF05793.12 EOO02784.1 - 9.8 4.6 20.9 0.22 10.1 13.5 1.9 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HK PF02110.15 EOO02785.1 - 2.3e-76 256.5 3.2 2.3e-76 256.5 3.2 1.9 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EOO02785.1 - 8.7e-58 194.6 1.6 1.3e-57 194.1 0.8 1.8 2 0 0 2 2 2 1 Thiamine monophosphate synthase Isochorismatase PF00857.20 EOO02785.1 - 4.5e-31 108.4 1.2 3.3e-30 105.5 0.2 2.8 3 1 0 3 3 3 1 Isochorismatase family Carb_kinase PF01256.17 EOO02785.1 - 0.00078 19.0 0.5 0.0018 17.8 0.5 1.6 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 EOO02785.1 - 0.015 14.6 0.4 0.043 13.2 0.2 1.8 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase PDT PF00800.18 EOO02786.1 - 1.4e-34 119.5 0.0 1.3e-33 116.3 0.0 2.0 1 1 1 2 2 2 1 Prephenate dehydratase ACT PF01842.25 EOO02786.1 - 2.5e-05 24.0 0.0 0.00019 21.1 0.0 2.4 3 0 0 3 3 3 1 ACT domain EamA PF00892.20 EOO02787.1 - 2.2e-05 24.6 29.5 0.00043 20.5 10.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family UPF0370 PF13980.6 EOO02787.1 - 0.2 11.7 1.1 0.33 11.0 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) WD40 PF00400.32 EOO02788.1 - 1.8e-58 193.1 12.6 2.5e-08 34.4 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 EOO02788.1 - 3.6e-17 62.4 12.0 6.7e-17 61.6 12.0 1.4 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 EOO02788.1 - 1.5e-15 57.2 0.0 0.0053 17.0 0.0 5.5 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EOO02788.1 - 4.4e-07 29.2 0.4 0.52 9.2 0.0 5.1 1 1 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EOO02788.1 - 1.1e-06 28.3 0.0 0.076 12.3 0.0 4.6 4 1 1 5 5 5 2 WD40-like domain Nup160 PF11715.8 EOO02788.1 - 0.00048 18.9 0.2 2.2 6.8 0.0 3.7 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EOO02788.1 - 0.011 14.3 0.4 0.44 9.0 0.2 2.6 1 1 2 3 3 3 0 Cytochrome D1 heme domain Filament PF00038.21 EOO02788.1 - 0.012 15.2 2.7 0.017 14.7 2.7 1.1 1 0 0 1 1 1 0 Intermediate filament protein PD40 PF07676.12 EOO02788.1 - 0.015 15.2 0.0 13 5.9 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Golgin_A5 PF09787.9 EOO02788.1 - 0.073 12.5 4.5 0.1 12.0 4.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 USP8_interact PF08941.10 EOO02788.1 - 0.12 12.2 0.7 0.17 11.7 0.7 1.2 1 0 0 1 1 1 0 USP8 interacting AIP3 PF03915.13 EOO02788.1 - 0.12 11.4 1.1 0.17 10.9 1.1 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Nucleoporin_N PF08801.11 EOO02788.1 - 0.13 11.0 0.2 3.9 6.1 0.1 3.1 2 1 0 2 2 2 0 Nup133 N terminal like SHE3 PF17078.5 EOO02788.1 - 0.15 11.8 3.3 0.21 11.3 3.3 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Nbas_N PF15492.6 EOO02788.1 - 0.16 11.3 0.0 24 4.2 0.0 3.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal TPX2 PF06886.11 EOO02788.1 - 5.7 7.3 7.2 39 4.6 7.2 1.9 1 1 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Pkinase PF00069.25 EOO02789.1 - 1e-69 234.8 0.0 2.2e-69 233.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO02789.1 - 2.8e-49 167.8 0.0 4.7e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 EOO02789.1 - 2.7e-26 91.8 0.0 5.5e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 EOO02789.1 - 5.4e-17 61.6 0.4 1.9e-16 59.9 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EOO02789.1 - 9.4e-16 58.0 0.1 1.8e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EOO02789.1 - 2.6e-13 50.4 0.1 4.8e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 EOO02789.1 - 7.5e-08 32.0 0.0 6.8e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EOO02789.1 - 0.0057 15.5 0.0 0.014 14.2 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase SAM_4 PF18017.1 EOO02789.1 - 0.017 15.1 0.0 0.05 13.6 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EOO02789.1 - 0.03 14.3 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain YjfB_motility PF14070.6 EOO02790.1 - 0.0012 18.9 1.7 0.003 17.7 1.7 1.6 1 0 0 1 1 1 1 Putative motility protein RasGAP_C PF03836.15 EOO02790.1 - 0.087 13.0 3.0 0.28 11.3 3.0 1.6 1 1 1 2 2 2 0 RasGAP C-terminus ARD PF03079.14 EOO02791.1 - 2.1e-44 151.4 0.1 2.6e-44 151.2 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EOO02791.1 - 3.1e-09 36.4 0.1 5.9e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EOO02791.1 - 2.6e-06 27.4 0.1 3.4e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain adh_short PF00106.25 EOO02792.1 - 1.1e-28 100.1 0.0 1.4e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO02792.1 - 3.6e-22 79.1 0.0 4.7e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO02792.1 - 8.1e-06 25.9 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO02792.1 - 0.0011 18.5 0.0 0.002 17.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SDH_alpha PF03313.15 EOO02792.1 - 0.0046 16.7 0.0 0.35 10.5 0.0 2.1 2 0 0 2 2 2 2 Serine dehydratase alpha chain Brix PF04427.18 EOO02793.1 - 5.7e-20 72.2 0.0 8.5e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.10 EOO02793.1 - 0.021 14.2 22.3 0.029 13.7 22.3 1.1 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 EOO02793.1 - 2.1 6.8 7.8 2.9 6.3 7.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 EOO02793.1 - 2.4 6.3 23.8 3.2 5.9 23.8 1.1 1 0 0 1 1 1 0 Nop14-like family ATP-synt_C PF00137.21 EOO02794.1 - 1.9e-21 76.2 20.9 3.5e-21 75.3 12.4 2.2 2 0 0 2 2 2 2 ATP synthase subunit C Lipase_GDSL_2 PF13472.6 EOO02795.1 - 1.7e-21 77.4 0.0 2.5e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EOO02795.1 - 2.2e-12 47.4 0.0 3.1e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pkinase PF00069.25 EOO02796.1 - 9.6e-55 185.8 0.0 2.7e-48 164.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EOO02796.1 - 2e-32 112.5 0.0 5.2e-31 107.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EOO02796.1 - 4.3e-08 32.8 0.0 1.9e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EOO02796.1 - 0.00035 20.6 0.3 0.00072 19.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EOO02796.1 - 0.003 16.4 0.0 0.0064 15.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase SMBP PF16785.5 EOO02796.1 - 0.19 12.0 1.1 0.38 11.0 1.1 1.5 1 0 0 1 1 1 0 Small metal-binding protein Pkinase PF00069.25 EOO02797.1 - 7e-52 176.4 0.0 1.2e-51 175.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO02797.1 - 1.1e-30 106.8 0.0 1.6e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EOO02797.1 - 1.1e-10 41.3 0.0 3.3e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EOO02797.1 - 0.043 13.2 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EOO02797.1 - 0.076 12.9 0.1 0.16 11.9 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L2_C PF03947.18 EOO02798.1 - 1.1e-40 138.8 5.8 1.1e-40 138.8 5.8 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EOO02798.1 - 2.2e-15 56.4 0.1 5.3e-15 55.1 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SPC12 PF06645.13 EOO02799.1 - 5.3e-30 103.3 0.4 6.4e-30 103.0 0.4 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) PfkB PF00294.24 EOO02800.1 - 1.7e-68 231.2 0.0 1.9e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EOO02800.1 - 0.0094 15.4 0.0 0.021 14.2 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Alpha-amylase PF00128.24 EOO02801.1 - 4.7e-48 164.5 0.2 5.3e-48 164.3 0.2 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 EOO02801.1 - 0.0045 16.1 0.0 0.0052 15.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Myb_DNA-bind_6 PF13921.6 EOO02802.1 - 7.7e-14 51.7 1.7 7.7e-14 51.7 1.7 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain HSA PF07529.13 EOO02802.1 - 9.6e-14 51.5 0.1 9.6e-14 51.5 0.1 3.4 3 0 0 3 3 3 1 HSA Myb_DNA-binding PF00249.31 EOO02802.1 - 3.4e-05 24.0 1.2 8.3e-05 22.7 1.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EOO02802.1 - 0.11 12.7 0.1 0.37 11.0 0.1 1.8 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 G-patch_2 PF12656.7 EOO02803.1 - 1.2e-11 44.5 0.6 7.7e-11 41.9 0.2 2.6 2 0 0 2 2 2 1 G-patch domain CPBP PF02517.16 EOO02804.1 - 4.8e-17 62.1 5.9 4.8e-17 62.1 5.9 2.8 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease MaoC_dehydratas PF01575.19 EOO02806.1 - 0.019 14.5 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 MaoC like domain eRF1_2 PF03464.15 EOO02807.1 - 2.1e-46 157.5 0.0 3.7e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EOO02807.1 - 6.7e-41 139.3 0.9 1.4e-40 138.3 0.9 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EOO02807.1 - 1.7e-21 76.6 0.0 2.9e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EOO02807.1 - 4.2e-10 40.0 0.2 3.2e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EOO02807.1 - 1.8e-08 34.7 0.0 3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor zf-Mss51 PF13824.6 EOO02808.1 - 1.5e-08 34.6 1.9 2.6e-08 33.8 1.9 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Aquarius_N PF16399.5 EOO02809.1 - 1.2e-297 989.4 0.0 1.9e-284 945.7 0.0 2.1 1 1 1 2 2 2 2 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 EOO02809.1 - 1.1e-27 97.0 0.0 1.7e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EOO02809.1 - 5e-22 78.9 0.0 1.5e-21 77.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EOO02809.1 - 2.2e-07 30.8 0.0 0.00039 20.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 EOO02809.1 - 4.2e-06 26.9 0.0 9.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EOO02809.1 - 2.3e-05 24.8 0.0 4.9e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EOO02809.1 - 0.00033 21.1 0.1 0.0029 18.0 0.1 2.8 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 EOO02809.1 - 0.0014 18.1 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.29 EOO02809.1 - 0.0022 18.4 0.0 0.0084 16.5 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EOO02809.1 - 0.0062 16.3 0.1 0.37 10.5 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EOO02809.1 - 0.023 15.0 0.1 0.16 12.3 0.1 2.4 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 EOO02809.1 - 0.038 13.8 0.0 0.086 12.6 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD_C_2 PF13538.6 EOO02809.1 - 0.043 13.7 0.7 0.15 11.9 0.1 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 EOO02809.1 - 0.046 13.2 1.3 0.36 10.3 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 EOO02809.1 - 0.05 12.9 0.0 0.05 12.9 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Pup PF05639.11 EOO02809.1 - 0.09 13.7 0.6 0.42 11.6 0.6 2.1 1 0 0 1 1 1 0 Pup-like protein PIF1 PF05970.14 EOO02809.1 - 0.16 11.1 0.1 16 4.5 0.0 2.7 3 0 0 3 3 3 0 PIF1-like helicase Parvo_NS1 PF01057.17 EOO02809.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SMC_N PF02463.19 EOO02809.1 - 0.18 11.2 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain PXA PF02194.15 EOO02810.1 - 1.2e-44 152.4 0.0 1.6e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 PXA domain RNA_pol_L_2 PF13656.6 EOO02811.1 - 1.6e-31 107.9 0.0 2.2e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EOO02811.1 - 1.4e-13 50.1 0.0 1.9e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF859 PF05895.12 EOO02811.1 - 0.19 10.2 0.0 0.21 10.0 0.0 1.0 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) Bmt2 PF11968.8 EOO02812.1 - 4.7e-48 163.9 0.0 5.3e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 DUF3463 PF11946.8 EOO02812.1 - 0.15 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) SNF2_N PF00176.23 EOO02813.1 - 3.6e-42 144.3 0.0 7.6e-42 143.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EOO02813.1 - 3.4e-20 72.4 0.0 9.3e-20 71.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO02813.1 - 2.4e-07 30.9 0.0 8.6e-07 29.1 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit 2OG-FeII_Oxy_2 PF13532.6 EOO02814.1 - 2.5e-12 47.4 0.0 1.9e-11 44.5 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aa_trans PF01490.18 EOO02815.1 - 4.1e-53 180.6 30.4 5.2e-53 180.2 30.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_59 PF02057.15 EOO02816.1 - 1.2e-15 57.6 3.4 1.6e-15 57.1 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EOO02816.1 - 3.6e-15 56.4 0.4 3.6e-15 56.4 0.4 1.8 1 1 1 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 EOO02816.1 - 5.6e-12 45.7 9.3 3.3e-11 43.2 9.3 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 EOO02816.1 - 8.2e-11 41.5 0.3 1.3e-10 40.8 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Aminotran_1_2 PF00155.21 EOO02817.1 - 1.7e-82 277.5 0.0 2.2e-82 277.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EOO02817.1 - 7.7e-05 21.4 0.0 0.00013 20.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EOO02817.1 - 0.00061 18.9 0.0 0.0026 16.8 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EOO02817.1 - 0.023 14.0 0.2 0.038 13.3 0.2 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3405 PF11885.8 EOO02817.1 - 0.026 13.1 0.2 0.039 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Sec1 PF00995.23 EOO02818.1 - 9.9e-121 404.7 0.8 3.6e-98 330.3 2.6 2.0 1 1 1 2 2 2 2 Sec1 family B12-binding PF02310.19 EOO02818.1 - 0.045 13.8 0.1 0.6 10.2 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain ATG101 PF07855.12 EOO02820.1 - 3.8e-55 186.1 0.2 4.4e-55 185.9 0.2 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 INSIG PF07281.12 EOO02821.1 - 6.8e-89 297.1 0.3 8.7e-89 296.7 0.3 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) GIDA PF01134.22 EOO02822.1 - 1.6e-158 527.9 0.0 1.9e-158 527.7 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EOO02822.1 - 1.3e-66 224.8 0.0 1.8e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 EOO02822.1 - 1.8e-06 27.6 0.2 3e-06 26.9 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EOO02822.1 - 6.5e-06 25.6 0.4 2e-05 24.0 0.4 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EOO02822.1 - 0.00025 20.2 1.8 0.00065 18.9 1.8 1.7 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EOO02822.1 - 0.026 13.8 0.8 0.026 13.8 0.8 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EOO02822.1 - 0.1 11.3 3.3 0.34 9.6 0.6 2.3 3 0 0 3 3 3 0 HI0933-like protein EF-hand_4 PF12763.7 EOO02823.1 - 1.6e-27 95.4 0.0 9.3e-15 54.5 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EOO02823.1 - 0.0002 21.7 0.1 0.49 10.9 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EOO02823.1 - 0.00024 20.5 0.0 0.5 10.0 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EOO02823.1 - 0.00094 18.9 0.0 6.1 7.0 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain ERM PF00769.19 EOO02823.1 - 0.0041 17.0 25.3 0.0041 17.0 25.3 4.7 3 2 1 4 4 4 1 Ezrin/radixin/moesin family E3_binding PF02817.17 EOO02823.1 - 0.088 13.2 0.3 0.28 11.6 0.3 1.8 1 0 0 1 1 1 0 e3 binding domain FPP PF05911.11 EOO02823.1 - 6.6 4.8 36.3 0.069 11.3 0.7 2.4 3 0 0 3 3 3 0 Filament-like plant protein, long coiled-coil Sybindin PF04099.12 EOO02824.1 - 1.5e-23 83.3 0.0 1.8e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Alpha-amylase PF00128.24 EOO02825.1 - 6e-32 111.5 0.1 1.3e-31 110.5 0.0 1.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EOO02825.1 - 4.6e-06 26.7 0.0 9.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Glyco_hydro_42C PF08533.10 EOO02825.1 - 0.0073 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain Alpha-amylase_C PF02806.18 EOO02825.1 - 0.072 13.6 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain CorA PF01544.18 EOO02826.1 - 9.5e-39 133.4 0.0 1.3e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein NAD_binding_8 PF13450.6 EOO02828.1 - 8.4e-14 51.6 0.1 2.4e-13 50.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EOO02828.1 - 7.1e-10 39.0 0.6 1.3e-07 31.6 0.0 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EOO02828.1 - 4e-08 32.8 0.1 2.9e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EOO02828.1 - 4.5e-08 32.6 0.8 7.1e-08 32.0 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EOO02828.1 - 9.9e-07 29.2 0.2 0.0011 19.5 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EOO02828.1 - 1.1e-06 28.0 0.0 3e-06 26.7 0.1 1.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EOO02828.1 - 1.6e-05 23.8 0.7 0.00016 20.6 0.4 2.0 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 EOO02828.1 - 5.6e-05 22.6 0.0 0.0032 16.8 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EOO02828.1 - 7.1e-05 22.9 0.1 0.0013 18.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EOO02828.1 - 0.0003 20.3 3.3 0.001 18.5 0.5 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EOO02828.1 - 0.00062 18.9 0.1 0.001 18.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EOO02828.1 - 0.0016 17.8 0.2 0.003 16.9 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S9 PF00326.21 EOO02828.1 - 0.017 14.6 0.1 0.041 13.3 0.1 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family FAD_binding_3 PF01494.19 EOO02828.1 - 0.023 14.0 0.1 0.054 12.7 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 EOO02828.1 - 0.025 13.4 0.2 0.045 12.6 0.2 1.4 1 0 0 1 1 1 0 Tryptophan halogenase GMC_oxred_N PF00732.19 EOO02828.1 - 0.039 13.3 0.0 0.67 9.3 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase K_oxygenase PF13434.6 EOO02828.1 - 0.057 12.6 0.0 0.59 9.2 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 EOO02828.1 - 0.098 13.1 0.1 0.28 11.7 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.16 EOO02828.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 EOO02828.1 - 0.36 9.9 0.7 0.53 9.3 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A CDP-OH_P_transf PF01066.21 EOO02829.1 - 9.3e-15 55.2 0.6 9.3e-15 55.2 0.6 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase adh_short PF00106.25 EOO02830.1 - 8.3e-46 155.9 0.1 1e-45 155.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO02830.1 - 3.2e-37 128.3 0.0 4.1e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO02830.1 - 8e-13 48.7 0.1 1e-12 48.3 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EOO02830.1 - 1.6e-05 24.5 0.0 0.00022 20.7 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) DFP PF04127.15 EOO02830.1 - 0.00064 19.6 0.1 0.001 18.9 0.1 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NAD_binding_10 PF13460.6 EOO02830.1 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EOO02830.1 - 0.009 15.6 0.1 0.02 14.5 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family 3HCDH_N PF02737.18 EOO02830.1 - 0.037 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EOO02830.1 - 0.077 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.17 EOO02830.1 - 0.085 11.9 0.0 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain AdoHcyase_NAD PF00670.21 EOO02830.1 - 0.1 12.7 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pkinase PF00069.25 EOO02831.1 - 1e-48 166.0 0.0 1.6e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO02831.1 - 1.2e-26 93.6 0.0 1.8e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EOO02831.1 - 0.0049 16.2 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EOO02831.1 - 0.0083 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EOO02831.1 - 0.083 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EOO02831.1 - 0.11 12.4 0.3 0.93 9.4 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family zf-rbx1 PF12678.7 EOO02832.1 - 7.7e-25 86.9 12.9 1.1e-24 86.5 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EOO02832.1 - 5.2e-17 61.7 9.8 6.8e-17 61.3 9.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EOO02832.1 - 5.1e-06 26.7 14.4 0.00018 21.8 14.4 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EOO02832.1 - 0.0016 18.3 11.3 0.027 14.4 11.3 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EOO02832.1 - 0.0016 18.2 14.2 0.11 12.3 14.2 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EOO02832.1 - 0.19 11.6 10.6 0.56 10.1 4.3 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EOO02832.1 - 0.33 10.7 15.8 27 4.6 15.8 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 EOO02832.1 - 0.46 10.5 6.9 1.7 8.8 6.9 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 EOO02832.1 - 1 9.6 9.2 5.9 7.1 9.5 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EOO02832.1 - 1.4 8.6 14.9 0.32 10.7 4.8 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EOO02832.1 - 7.4 6.6 12.3 62 3.7 12.3 2.5 1 1 0 1 1 1 0 zinc-RING finger domain MMM1 PF10296.9 EOO02833.1 - 5.6e-140 466.1 0.1 1.8e-138 461.1 0.1 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 BioT2 PF15368.6 EOO02833.1 - 0.54 10.2 1.8 1.2 9.1 0.3 2.2 2 1 1 3 3 3 0 Spermatogenesis family BioT2 Pep3_Vps18 PF05131.14 EOO02834.1 - 4.8e-50 169.2 0.1 1.4e-49 167.8 0.1 1.8 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EOO02834.1 - 1.5e-10 41.1 2.7 2.4e-07 30.7 0.1 3.4 2 1 1 3 3 3 2 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 EOO02834.1 - 0.00057 19.7 0.5 0.0014 18.4 0.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EOO02834.1 - 0.00074 19.1 0.5 0.0015 18.1 0.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type DUF2175 PF09943.9 EOO02834.1 - 0.0015 18.7 1.1 0.0086 16.3 0.1 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_5 PF14634.6 EOO02834.1 - 0.0019 18.1 1.4 0.0019 18.1 1.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EOO02834.1 - 0.0074 16.6 1.1 0.017 15.4 1.1 1.7 1 0 0 1 1 1 1 Ring finger domain Vps39_2 PF10367.9 EOO02834.1 - 0.029 14.8 0.0 0.069 13.6 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-RING_11 PF17123.5 EOO02834.1 - 0.04 13.7 8.8 0.024 14.4 4.2 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 EOO02834.1 - 0.083 12.9 1.7 0.2 11.7 1.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 EOO02834.1 - 0.1 12.9 0.2 0.26 11.6 0.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain SopA PF13981.6 EOO02834.1 - 0.11 12.9 0.4 0.74 10.3 0.1 2.6 3 0 0 3 3 3 0 SopA-like central domain zf-C3H2C3 PF17122.5 EOO02834.1 - 1.3 9.2 6.8 0.14 12.2 2.2 1.8 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4 PF00097.25 EOO02834.1 - 3.3 7.6 5.1 0.55 10.2 0.9 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GFA PF04828.14 EOO02835.1 - 0.0072 16.6 4.0 1.1 9.7 0.4 2.6 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme efThoc1 PF11957.8 EOO02836.1 - 1.9e-138 462.2 8.7 2.3e-138 461.9 8.7 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor WD40 PF00400.32 EOO02837.1 - 2.7e-13 50.2 0.1 0.033 15.1 0.0 6.8 8 0 0 8 8 8 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EOO02837.1 - 0.00012 21.0 0.0 0.13 11.0 0.0 3.0 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 EOO02837.1 - 0.0017 17.1 0.0 0.0075 15.0 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EOO02837.1 - 0.0075 16.5 0.0 1.2 9.5 0.0 3.5 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Asp PF00026.23 EOO02838.1 - 6.8e-42 144.0 0.2 9.8e-42 143.5 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EOO02838.1 - 1.6e-05 24.7 0.0 3.4e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal zf-Tim10_DDP PF02953.15 EOO02839.1 - 4.6e-22 77.4 1.2 6.1e-22 77.1 1.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger GA PF01468.17 EOO02839.1 - 0.11 12.8 1.1 0.15 12.4 1.1 1.3 1 0 0 1 1 1 0 GA module Gti1_Pac2 PF09729.9 EOO02840.1 - 9.6e-59 198.5 0.0 1.7e-58 197.7 0.0 1.4 1 1 0 1 1 1 1 Gti1/Pac2 family AIG2_2 PF13772.6 EOO02841.1 - 2.3e-05 24.7 0.0 3.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 EOO02841.1 - 0.0011 19.5 0.0 0.0028 18.2 0.0 1.6 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like GDP_Man_Dehyd PF16363.5 EOO02842.1 - 8e-70 235.8 0.0 9.3e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EOO02842.1 - 3.2e-56 190.5 0.0 4e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EOO02842.1 - 5.3e-24 84.9 0.0 5e-23 81.7 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EOO02842.1 - 4e-21 75.2 0.0 5.2e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EOO02842.1 - 1.2e-18 67.2 0.0 1.6e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EOO02842.1 - 2e-18 66.5 0.2 3.7e-17 62.3 0.2 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EOO02842.1 - 3.2e-07 30.4 0.0 5.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EOO02842.1 - 0.032 13.7 0.0 1.9 7.9 0.1 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Lipase3_N PF03893.16 EOO02842.1 - 0.13 12.3 0.0 32 4.6 0.0 3.0 3 0 0 3 3 3 0 Lipase 3 N-terminal region TPT PF03151.16 EOO02843.1 - 7.1e-06 25.6 20.7 1.6e-05 24.4 20.7 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family CMAS PF02353.20 EOO02844.1 - 2.8e-60 203.9 0.0 3.5e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EOO02844.1 - 5.8e-10 39.2 0.0 1.3e-09 38.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO02844.1 - 5.9e-10 39.7 0.0 1.3e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO02844.1 - 2e-09 38.0 0.0 4.5e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO02844.1 - 0.0049 17.6 0.0 0.012 16.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EOO02844.1 - 0.023 14.4 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 EOO02844.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MBOAT PF03062.19 EOO02845.1 - 1.6e-53 182.3 8.0 2.7e-53 181.6 8.0 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Forkhead PF00250.18 EOO02846.1 - 4.7e-34 116.5 0.1 1.5e-33 114.9 0.1 1.8 1 0 0 1 1 1 1 Forkhead domain HGTP_anticodon PF03129.20 EOO02847.1 - 3.5e-24 84.8 0.9 8e-23 80.4 0.0 3.0 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EOO02847.1 - 6.7e-08 32.7 0.0 3.7e-07 30.3 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) TENA_THI-4 PF03070.16 EOO02847.1 - 0.11 12.3 0.0 11 5.8 0.1 2.3 2 0 0 2 2 2 0 TENA/THI-4/PQQC family Ribosomal_L23eN PF03939.13 EOO02849.1 - 2.6e-26 91.5 9.9 2.6e-26 91.5 9.9 2.6 2 1 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EOO02849.1 - 3.1e-15 56.3 1.7 3.2e-15 56.2 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L23 MMR_HSR1_Xtn PF16897.5 EOO02850.1 - 1.2e-40 137.8 0.6 1.1e-39 134.7 0.5 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EOO02850.1 - 4.4e-21 75.1 0.0 3e-20 72.4 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 EOO02850.1 - 7.6e-19 67.5 0.0 1.7e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EOO02850.1 - 8.4e-09 35.1 0.0 3.8e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EOO02850.1 - 0.00042 19.9 0.1 4.8 6.7 0.0 3.7 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EOO02850.1 - 0.00065 19.8 0.1 0.17 12.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 EOO02850.1 - 0.0061 15.6 0.2 0.025 13.5 0.1 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 EOO02850.1 - 0.048 13.1 0.1 7.5 6.0 0.1 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EOO02850.1 - 0.06 13.2 0.6 6.8 6.6 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase AAA_22 PF13401.6 EOO02850.1 - 0.066 13.5 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EOO02850.1 - 0.073 13.3 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase G10 PF01125.17 EOO02851.1 - 7.4e-38 129.6 0.8 8.5e-38 129.4 0.8 1.0 1 0 0 1 1 1 1 G10 protein SNase PF00565.17 EOO02851.1 - 0.065 13.7 0.0 0.079 13.4 0.0 1.1 1 0 0 1 1 1 0 Staphylococcal nuclease homologue DUF1040 PF06288.13 EOO02851.1 - 0.091 13.1 0.0 1.2 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) Peroxin-3 PF04882.12 EOO02852.1 - 5.4e-168 559.8 0.0 6.4e-168 559.6 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 EPO_TPO PF00758.18 EOO02852.1 - 0.039 14.0 0.2 0.12 12.4 0.2 1.8 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin DUF5345 PF17280.2 EOO02852.1 - 0.099 12.6 0.1 6.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DER1 PF04511.15 EOO02853.1 - 2e-50 171.4 6.4 2.3e-50 171.2 6.4 1.0 1 0 0 1 1 1 1 Der1-like family Methyltransf_23 PF13489.6 EOO02854.1 - 4.1e-15 56.0 0.0 6.7e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO02854.1 - 5.6e-10 39.8 0.0 1.5e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO02854.1 - 1.2e-09 38.8 0.0 3.1e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO02854.1 - 6.2e-08 32.6 0.0 5.3e-07 29.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO02854.1 - 9.1e-08 32.7 0.0 2.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EOO02854.1 - 2.3e-06 27.2 0.0 4.6e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 EOO02854.1 - 0.00058 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 EOO02854.1 - 0.00097 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EOO02854.1 - 0.016 14.6 0.0 0.055 12.8 0.0 1.8 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family GARS_A PF01071.19 EOO02855.1 - 6.9e-85 283.7 0.8 6.8e-84 280.5 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 EOO02855.1 - 6.1e-34 116.7 0.1 4.3e-33 114.0 0.0 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 EOO02855.1 - 1.3e-33 116.4 0.3 4.8e-33 114.5 0.1 2.0 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 EOO02855.1 - 3.3e-26 91.4 1.2 1.3e-25 89.5 0.5 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EOO02855.1 - 2.1e-13 50.7 4.0 2.1e-13 50.7 4.0 2.4 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 EOO02855.1 - 0.00048 19.7 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EOO02855.1 - 0.0029 17.1 0.0 0.0064 16.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 EOO02855.1 - 0.02 14.9 0.0 0.054 13.6 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_4 PF13535.6 EOO02855.1 - 0.037 13.6 0.0 0.086 12.4 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 EOO02855.1 - 0.064 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Tyr-DNA_phospho PF06087.12 EOO02856.1 - 1.4e-41 142.8 0.0 2.2e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 EOO02856.1 - 9.3e-05 22.1 0.4 9.3e-05 22.1 0.4 2.7 2 0 0 2 2 2 1 Ubiquitin interaction motif MRP-S31 PF15433.6 EOO02856.1 - 0.0028 17.4 4.3 0.0038 17.0 4.3 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 Macoilin PF09726.9 EOO02856.1 - 0.0097 14.5 0.2 0.01 14.4 0.2 1.1 1 0 0 1 1 1 1 Macoilin family pRN1_helical PF13010.6 EOO02856.1 - 0.1 12.6 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Primase helical domain FAM110_C PF14160.6 EOO02856.1 - 1.8 9.7 6.1 13 6.9 1.0 3.1 2 1 1 3 3 3 0 Centrosome-associated C terminus Ank_2 PF12796.7 EOO02857.1 - 1.1e-18 67.5 0.0 3.8e-12 46.6 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EOO02857.1 - 3.4e-11 43.1 1.7 0.00014 22.2 0.1 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EOO02857.1 - 7.1e-11 42.1 1.8 0.0015 18.8 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EOO02857.1 - 9.8e-11 42.0 0.0 0.0022 18.5 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EOO02857.1 - 3.3e-09 36.2 0.6 0.0069 16.8 0.1 5.3 5 0 0 5 5 5 2 Ankyrin repeat STE3 PF02076.15 EOO02858.1 - 8.4e-70 235.2 20.0 9.7e-70 235.0 20.0 1.0 1 0 0 1 1 1 1 Pheromone A receptor SSB PF00436.25 EOO02859.1 - 2e-20 72.7 0.0 2.4e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF4741 PF15897.5 EOO02859.1 - 0.032 14.0 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4741) Nexin_C PF08628.12 EOO02860.1 - 0.19 12.3 0.0 0.27 11.8 0.0 1.3 1 0 0 1 1 1 0 Sorting nexin C terminal FA_hydroxylase PF04116.13 EOO02861.1 - 3e-25 89.1 24.1 7.3e-25 87.9 17.8 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily zf-U1 PF06220.12 EOO02862.1 - 0.54 10.1 3.8 7.1 6.5 0.2 2.1 2 0 0 2 2 2 0 U1 zinc finger DUF2633 PF11119.8 EOO02862.1 - 8.9 6.3 7.8 11 6.0 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2633) Ldh_1_C PF02866.18 EOO02863.1 - 2.9e-49 167.2 0.0 4.1e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EOO02863.1 - 1e-42 145.6 0.1 1.6e-42 145.0 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EOO02863.1 - 0.069 12.2 0.0 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2015 PF09435.10 EOO02864.1 - 1.6e-47 159.9 0.0 1.9e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) TRAPP PF04051.16 EOO02865.1 - 2.3e-46 157.1 0.0 2.8e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ribosomal_L28e PF01778.17 EOO02866.1 - 7.5e-37 126.6 0.4 9.5e-37 126.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF4150 PF13665.6 EOO02866.1 - 0.053 13.7 0.4 0.09 12.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4150) DUF3328 PF11807.8 EOO02867.1 - 3.6e-46 157.7 0.0 4.4e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2423 PF10338.9 EOO02868.1 - 1.2e-20 73.4 4.0 1.2e-20 73.4 4.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) TP53IP5 PF15331.6 EOO02868.1 - 0.31 11.2 11.1 0.33 11.1 11.1 1.0 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Glyco_hydro_16 PF00722.21 EOO02869.1 - 1.3e-45 155.1 3.6 2.1e-45 154.4 3.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 EOO02869.1 - 0.016 15.7 11.9 0.016 15.7 11.9 1.9 2 0 0 2 2 2 0 Chitin recognition protein Sugar_tr PF00083.24 EOO02870.1 - 2.8e-68 230.8 6.1 3.2e-68 230.7 6.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO02870.1 - 1.4e-14 53.9 22.7 2.1e-09 36.8 7.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Prok-RING_4 PF14447.6 EOO02871.1 - 1.6e-05 24.6 3.5 6.1e-05 22.8 0.8 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EOO02871.1 - 9.1e-05 22.4 3.9 0.00019 21.4 3.9 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EOO02871.1 - 0.0002 21.3 4.9 0.00069 19.5 4.9 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EOO02871.1 - 0.001 18.9 1.0 0.001 18.9 1.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EOO02871.1 - 0.0014 18.5 3.0 0.0034 17.2 3.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EOO02871.1 - 0.0056 16.5 1.8 0.055 13.3 0.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EOO02871.1 - 0.0077 16.5 3.3 0.018 15.4 1.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 EOO02871.1 - 0.034 14.3 1.9 0.11 12.7 0.4 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 EOO02871.1 - 0.087 13.0 2.6 0.25 11.5 1.0 2.3 2 1 0 2 2 2 0 Zinc-binding RING-finger FYVE PF01363.21 EOO02871.1 - 0.14 12.3 6.8 0.43 10.8 6.8 1.8 1 1 0 1 1 1 0 FYVE zinc finger Sec62 PF03839.16 EOO02872.1 - 5.3 6.5 8.6 8.6 5.8 8.6 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 ILVD_EDD PF00920.21 EOO02873.1 - 1.2e-207 690.7 0.4 1.3e-207 690.5 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family PhzC-PhzF PF02567.16 EOO02874.1 - 8.7e-34 117.3 0.2 1.4e-33 116.5 0.2 1.4 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein adh_short PF00106.25 EOO02875.1 - 8.1e-21 74.4 0.0 1e-18 67.5 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO02875.1 - 6.5e-07 29.1 0.0 0.0075 15.8 0.0 2.3 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO02875.1 - 0.0014 18.6 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EOO02875.1 - 0.0047 16.8 0.1 0.0082 16.1 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Prp19 PF08606.11 EOO02876.1 - 9.7e-34 115.2 3.0 9.7e-34 115.2 3.0 1.8 2 0 0 2 2 2 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 EOO02876.1 - 8.6e-11 42.0 0.0 0.0003 21.0 0.0 4.8 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EOO02876.1 - 9.5e-11 42.1 0.0 0.064 14.1 0.0 5.5 6 0 0 6 6 5 2 WD domain, G-beta repeat Gmad1 PF10647.9 EOO02876.1 - 6.2e-05 22.9 0.2 6.2e-05 22.9 0.2 2.1 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain VID27 PF08553.10 EOO02876.1 - 0.00018 20.7 0.4 0.0022 17.1 0.1 2.2 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain eIF2A PF08662.11 EOO02876.1 - 0.0008 19.3 0.0 0.33 10.8 0.0 2.9 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 EOO02876.1 - 0.0013 17.8 0.0 0.08 12.0 0.0 2.4 1 1 0 1 1 1 1 Coatomer WD associated region V_ATPase_I_N PF18670.1 EOO02876.1 - 0.0014 19.0 0.6 0.0042 17.4 0.2 2.0 2 0 0 2 2 2 1 V-type ATPase subunit I, N-terminal domain zf-Nse PF11789.8 EOO02876.1 - 0.0033 17.2 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Mcl1_mid PF12341.8 EOO02876.1 - 0.0092 15.4 0.1 0.089 12.1 0.0 2.2 1 1 1 2 2 2 1 Minichromosome loss protein, Mcl1, middle region U-box PF04564.15 EOO02876.1 - 0.013 15.6 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 U-box domain ADIP PF11559.8 EOO02876.1 - 0.053 13.6 0.3 0.095 12.8 0.3 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4604 PF15377.6 EOO02877.1 - 5.2e-33 114.9 10.0 6e-33 114.7 10.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Aldo_ket_red PF00248.21 EOO02878.1 - 3.9e-39 134.6 0.0 1.1e-26 93.7 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family OHCU_decarbox PF09349.10 EOO02879.1 - 6e-43 147.0 0.0 7.3e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Arg_decarbox_C PF17944.1 EOO02879.1 - 0.17 12.4 0.0 0.45 11.1 0.0 1.8 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension Myb_DNA-binding PF00249.31 EOO02880.1 - 2.1e-12 47.0 0.7 6.5e-06 26.3 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EOO02880.1 - 6.1e-07 29.6 0.3 0.021 15.1 0.0 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rax2 PF12768.7 EOO02880.1 - 0.016 14.7 0.1 0.018 14.5 0.1 1.0 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Myb_DNA-bind_2 PF08914.11 EOO02880.1 - 0.05 13.8 0.5 0.13 12.4 0.1 1.8 1 1 1 2 2 2 0 Rap1 Myb domain Glyco_transf_15 PF01793.16 EOO02881.1 - 3.6e-92 309.1 7.1 5.2e-91 305.3 7.1 2.0 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase eRF1_1 PF03463.15 EOO02882.1 - 5.5e-44 149.3 0.0 9.6e-44 148.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 EOO02882.1 - 4.3e-21 75.5 0.0 9.3e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 EOO02882.1 - 2e-19 70.3 0.0 3.3e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 Peptidase_M6 PF05547.11 EOO02883.1 - 0.0091 14.4 1.1 0.076 11.3 1.0 1.9 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 DUF2332 PF10094.9 EOO02884.1 - 0.0071 15.8 0.2 0.022 14.2 0.2 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2332) COX5B PF01215.19 EOO02885.1 - 2.7e-58 195.3 0.1 3.5e-58 194.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Dabb PF07876.12 EOO02886.1 - 1.1e-22 80.4 0.0 1.3e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Proteasome PF00227.26 EOO02887.1 - 4.8e-49 166.4 0.0 6.7e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EOO02887.1 - 7.1e-13 48.0 0.1 1.5e-12 46.9 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature C2 PF00168.30 EOO02888.1 - 8.2e-18 64.6 0.0 1.1e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 C2 domain OB_NTP_bind PF07717.16 EOO02890.1 - 8.6e-20 70.9 0.0 1.8e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EOO02890.1 - 2.7e-19 69.5 0.0 2.7e-19 69.5 0.0 4.1 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EOO02890.1 - 5.7e-13 49.2 0.0 1.6e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EOO02890.1 - 2.6e-06 27.7 0.0 8.4e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EOO02890.1 - 3.9e-06 26.8 0.1 9.2e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EOO02890.1 - 0.00058 19.6 0.1 0.0013 18.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EOO02890.1 - 0.0017 17.5 0.0 0.0039 16.3 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 EOO02890.1 - 0.0072 16.7 0.1 0.015 15.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EOO02890.1 - 0.034 13.8 0.0 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 EOO02890.1 - 0.057 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.27 EOO02890.1 - 0.07 13.6 0.3 0.24 11.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Con-6 PF10346.9 EOO02891.1 - 1.7e-31 107.9 6.5 3.2e-17 62.3 0.3 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.7 EOO02891.1 - 0.13 12.1 0.4 0.13 12.1 0.4 1.8 1 1 1 2 2 2 0 SpoIIIAH-like protein Glyco_transf_8 PF01501.20 EOO02893.1 - 2.2e-11 43.8 0.0 8.9e-11 41.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 MMR_HSR1_C PF08438.10 EOO02894.1 - 4.4e-37 127.1 0.0 7.8e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EOO02894.1 - 7e-10 39.0 0.0 2.1e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EOO02894.1 - 0.044 13.8 0.4 0.1 12.6 0.1 1.7 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 EOO02894.1 - 0.071 13.0 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF2373 PF10180.9 EOO02895.1 - 9.3e-24 83.0 0.1 1.7e-23 82.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) TMEM234 PF10639.9 EOO02896.1 - 6.4e-36 122.9 0.2 8.8e-36 122.5 0.2 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 EOO02896.1 - 0.0019 18.3 7.4 0.066 13.4 7.4 2.1 1 1 0 1 1 1 1 EamA-like transporter family DnaJ_C PF01556.18 EOO02897.1 - 1.1e-28 100.2 0.0 1.6e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EOO02897.1 - 1.7e-26 92.1 2.4 3.7e-26 91.0 2.4 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EOO02897.1 - 1.8e-13 50.6 17.9 3.2e-13 49.8 17.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EOO02897.1 - 0.00058 19.8 9.5 0.021 14.8 0.7 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EOO02897.1 - 0.0027 17.7 8.4 0.21 11.6 1.3 2.2 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Nop10p PF04135.12 EOO02897.1 - 0.2 11.7 0.3 0.71 10.0 0.3 1.9 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family TackOD1 PF18551.1 EOO02897.1 - 2.4 7.8 5.9 4.7 6.8 0.4 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Lar_restr_allev PF14354.6 EOO02897.1 - 3.2 8.2 10.2 6.7 7.2 0.3 3.2 1 1 2 3 3 3 0 Restriction alleviation protein Lar DZR PF12773.7 EOO02897.1 - 9.6 6.3 9.9 45 4.2 9.9 2.0 1 1 0 1 1 1 0 Double zinc ribbon MFS_1 PF07690.16 EOO02898.1 - 3.5e-12 45.9 25.7 1.5e-08 33.9 8.6 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily DUF1761 PF08570.10 EOO02899.1 - 2.4e-26 92.4 4.0 2.7e-26 92.3 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Fungal_trans PF04082.18 EOO02900.1 - 1.7e-33 115.8 0.3 2.7e-33 115.1 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EOO02900.1 - 1.2e-08 34.9 14.6 2.3e-08 34.0 14.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 EOO02900.1 - 0.028 14.5 0.2 0.093 12.8 0.2 2.0 1 0 0 1 1 1 0 bZIP transcription factor DUF1440 PF07274.12 EOO02900.1 - 0.17 12.2 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) DUF4635 PF15466.6 EOO02900.1 - 0.66 9.5 3.0 0.33 10.5 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) zf-C2H2 PF00096.26 EOO02901.1 - 0.00092 19.5 15.4 0.16 12.5 3.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type COG2 PF06148.11 EOO02901.1 - 0.014 15.5 3.1 0.025 14.7 3.1 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Macoilin PF09726.9 EOO02901.1 - 0.014 14.0 0.4 0.017 13.7 0.4 1.1 1 0 0 1 1 1 0 Macoilin family zf-C2H2_8 PF15909.5 EOO02901.1 - 0.019 15.3 0.1 0.035 14.4 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc ribbon APG6_N PF17675.1 EOO02901.1 - 0.02 15.4 1.9 0.028 14.9 1.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF812 PF05667.11 EOO02901.1 - 0.025 13.5 2.0 0.032 13.1 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 EOO02901.1 - 0.063 12.6 2.1 0.086 12.2 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 EOO02901.1 - 0.071 12.2 0.4 0.096 11.8 0.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3450 PF11932.8 EOO02901.1 - 0.12 11.6 6.2 0.18 11.1 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GAS PF13851.6 EOO02901.1 - 0.13 11.6 6.1 0.19 11.0 6.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding COG6 PF06419.11 EOO02901.1 - 0.16 10.2 2.7 0.21 9.7 2.7 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 ZapB PF06005.12 EOO02901.1 - 0.3 11.5 10.6 0.59 10.6 10.6 1.4 1 0 0 1 1 1 0 Cell division protein ZapB zf-H2C2_5 PF13909.6 EOO02901.1 - 0.34 10.7 0.2 0.34 10.7 0.2 3.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 EOO02901.1 - 0.35 11.8 11.9 19 6.4 2.9 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger TMF_DNA_bd PF12329.8 EOO02901.1 - 0.58 10.2 7.5 1.6 8.8 7.4 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding zf-C2H2_aberr PF17017.5 EOO02901.1 - 0.75 9.9 0.0 0.75 9.9 0.0 2.0 3 0 0 3 3 3 0 Aberrant zinc-finger Bap31_Bap29_C PF18035.1 EOO02901.1 - 1.9 8.5 3.9 4.1 7.5 3.9 1.6 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain bZIP_2 PF07716.15 EOO02901.1 - 6.9 6.8 14.5 2 8.6 4.3 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Shugoshin_N PF07558.11 EOO02901.1 - 8 6.4 8.5 5.7 6.9 1.7 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Adenylsucc_synt PF00709.21 EOO02902.1 - 5.9e-29 101.2 0.0 7.1e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase UTP15_C PF09384.10 EOO02903.1 - 1.4e-49 167.6 0.0 1.5e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 UTP15 C terminal DUF5308 PF17233.2 EOO02904.1 - 8e-40 136.8 6.7 3.5e-39 134.7 6.7 1.9 1 1 0 1 1 1 1 Family of unknown function (DUF5308) Spt5_N PF11942.8 EOO02904.1 - 0.71 10.9 6.1 1.6 9.7 1.8 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CDK2AP PF09806.9 EOO02904.1 - 2.2 8.3 9.1 0.59 10.2 2.7 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein ATG2_CAD PF13329.6 EOO02905.1 - 6.1e-54 182.0 1.7 1.4e-53 180.8 0.9 2.1 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 EOO02905.1 - 1e-33 115.6 2.9 1.5e-33 115.0 0.3 2.8 4 0 0 4 4 4 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 EOO02905.1 - 0.00012 22.2 0.1 0.00046 20.3 0.1 2.0 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 EOO02905.1 - 0.088 12.6 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal FAD_binding_3 PF01494.19 EOO02906.1 - 1.6e-05 24.4 0.1 1.9e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain SIS PF01380.22 EOO02907.1 - 1.1e-11 44.7 0.0 2.3e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 EOO02907.1 - 0.0021 18.1 0.1 0.0057 16.7 0.1 1.7 1 1 0 1 1 1 1 SIS domain Translin PF01997.16 EOO02908.1 - 4.6e-40 137.8 0.6 2e-38 132.4 0.6 2.0 1 1 0 1 1 1 1 Translin family betaPIX_CC PF16523.5 EOO02908.1 - 0.074 12.9 0.4 0.41 10.5 0.0 2.2 2 0 0 2 2 2 0 betaPIX coiled coil NIL PF09383.10 EOO02908.1 - 0.076 12.9 0.0 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 NIL domain Ribosomal_L22e PF01776.17 EOO02909.1 - 2.3e-44 150.2 0.6 5e-44 149.1 0.6 1.5 1 0 0 1 1 1 1 Ribosomal L22e protein family GDPD PF03009.17 EOO02909.1 - 1.4e-11 44.7 0.0 2.1e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EOO02909.1 - 0.00029 21.2 0.1 0.0006 20.2 0.1 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PIG-F PF06699.11 EOO02910.1 - 1.2e-65 221.0 5.7 1.4e-65 220.8 5.7 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F TauE PF01925.19 EOO02910.1 - 0.18 11.4 20.6 0.026 14.2 14.6 1.9 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE Ribosomal_L7Ae PF01248.26 EOO02911.1 - 4e-20 71.3 0.3 3.2e-19 68.5 0.3 2.3 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FHIPEP PF00771.20 EOO02911.1 - 0.4 9.1 3.1 0.68 8.3 3.1 1.6 1 1 0 1 1 1 0 FHIPEP family Spore_III_AF PF09581.10 EOO02911.1 - 0.93 9.5 11.2 0.18 11.8 4.9 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) TipAS PF07739.13 EOO02911.1 - 1.2 9.7 10.7 0.99 10.0 5.7 2.4 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DUF5352 PF17303.2 EOO02911.1 - 3.7 7.4 8.5 1.8 8.4 5.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5352) CENP-B_dimeris PF09026.10 EOO02911.1 - 9.7 6.7 11.4 6.7 7.2 0.3 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Mito_carr PF00153.27 EOO02912.1 - 2e-52 175.1 0.5 6.6e-18 64.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CENP-F_N PF10481.9 EOO02913.1 - 0.0052 16.5 17.6 0.0052 16.5 17.6 4.7 4 1 2 6 6 6 1 Cenp-F N-terminal domain PRKG1_interact PF15898.5 EOO02913.1 - 0.0062 17.4 2.4 0.0062 17.4 2.4 6.9 6 2 2 8 8 8 2 cGMP-dependent protein kinase interacting domain Shugoshin_N PF07558.11 EOO02913.1 - 1.5 8.7 15.2 2.6 8.0 0.1 5.0 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region DUF3824 PF12868.7 EOO02914.1 - 1.7e-09 38.5 83.7 1.4e-07 32.3 11.9 12.5 4 4 7 11 11 11 4 Domain of unknwon function (DUF3824) Phage_holin_3_3 PF16083.5 EOO02914.1 - 2.5 8.3 3.8 7.4 6.8 0.3 3.0 3 0 0 3 3 3 0 LydA holin phage, holin superfamily III WD40 PF00400.32 EOO02915.1 - 2.3e-41 139.0 18.0 1.1e-05 26.1 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EOO02915.1 - 1e-11 44.6 0.1 2.1e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EOO02915.1 - 7.7e-11 41.6 0.5 4.3e-10 39.2 0.3 2.3 2 1 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 EOO02915.1 - 4.8e-09 36.4 1.4 1.4 9.3 0.0 5.8 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EOO02915.1 - 0.0032 17.1 0.6 0.12 11.9 0.4 2.6 1 1 1 2 2 2 2 PQQ-like domain F-box_4 PF15966.5 EOO02915.1 - 0.0046 16.8 0.1 0.018 14.9 0.0 2.1 2 0 0 2 2 2 1 F-box Nup160 PF11715.8 EOO02915.1 - 0.014 14.1 5.7 8.5 4.9 0.0 4.8 3 1 3 6 6 6 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EOO02915.1 - 0.054 12.2 2.2 14 4.3 0.1 4.4 3 2 2 5 5 5 0 Nup133 N terminal like DUF4597 PF15366.6 EOO02915.1 - 0.086 12.6 0.2 0.7 9.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) DUF5046 PF16465.5 EOO02915.1 - 0.18 11.2 0.0 9.9 5.5 0.0 3.1 2 2 2 4 4 4 0 Domain of unknown function (DUF5046) Podoplanin PF05808.11 EOO02916.1 - 0.0029 17.7 1.2 0.0062 16.7 1.2 1.5 1 0 0 1 1 1 1 Podoplanin Sporozoite_P67 PF05642.11 EOO02916.1 - 0.012 13.8 4.8 0.016 13.3 4.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SKG6 PF08693.10 EOO02916.1 - 0.013 14.9 1.0 0.013 14.9 1.0 2.4 3 0 0 3 3 3 0 Transmembrane alpha-helix domain Mid2 PF04478.12 EOO02916.1 - 0.11 12.3 1.3 0.25 11.1 0.1 1.9 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor Mid1 PF12929.7 EOO02917.1 - 4.3e-152 507.2 8.1 4.9e-152 507.0 8.1 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EOO02917.1 - 3.4e-05 24.4 7.9 0.0049 17.5 4.0 2.8 2 1 0 2 2 2 2 Fz domain HP_OMP PF01856.17 EOO02917.1 - 0.052 13.6 1.9 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 Helicobacter outer membrane protein Rdx PF10262.9 EOO02917.1 - 0.06 13.6 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Rdx family PS_Dcarbxylase PF02666.15 EOO02918.1 - 1e-77 260.2 0.0 6.2e-76 254.4 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 EOO02918.1 - 0.074 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like DUF4202 PF13875.6 EOO02919.1 - 1.4e-62 210.9 1.3 1.3e-61 207.8 1.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4202) DUF1793 PF08760.11 EOO02921.1 - 2.9e-76 255.6 2.2 2.9e-76 255.5 0.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 EOO02921.1 - 8.5e-64 214.4 0.2 4.7e-50 169.6 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EOO02921.1 - 1.8e-48 165.3 1.1 2.9e-48 164.6 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) Glyco_hydr_116N PF12215.8 EOO02921.1 - 0.043 13.3 0.1 0.073 12.5 0.1 1.3 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Glyco_transf_8 PF01501.20 EOO02923.1 - 3.1e-22 79.4 1.7 4.2e-21 75.6 1.7 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 DUF294_C PF10335.9 EOO02923.1 - 0.24 11.2 0.1 1.1 9.1 0.1 1.9 1 1 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain PepX_C PF08530.10 EOO02924.1 - 1e-44 153.2 0.2 1.6e-44 152.5 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 EOO02924.1 - 1.2e-37 130.0 0.0 1.8e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EOO02924.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cation_efflux PF01545.21 EOO02925.1 - 6.2e-12 45.7 10.0 8.8e-12 45.2 10.0 1.2 1 0 0 1 1 1 1 Cation efflux family XdhC_CoxI PF02625.16 EOO02926.1 - 0.034 14.3 5.3 0.034 14.3 2.2 2.2 2 1 0 2 2 2 0 XdhC and CoxI family Frag1 PF10277.9 EOO02927.1 - 5.6e-44 150.3 13.2 6.7e-44 150.0 13.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3611 PF12263.8 EOO02927.1 - 4.4 7.2 12.3 2.4 8.0 4.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) EMP70 PF02990.16 EOO02927.1 - 4.6 5.8 9.4 15 4.1 9.6 1.5 1 1 0 1 1 1 0 Endomembrane protein 70 Eisosome1 PF12757.7 EOO02928.1 - 2.7e-47 160.1 14.0 2.7e-47 160.1 14.0 3.8 3 0 0 3 3 3 1 Eisosome protein 1 PDEase_I_N PF08499.12 EOO02928.1 - 0.014 15.2 0.0 0.087 12.7 0.0 2.5 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal MbeD_MobD PF04899.12 EOO02929.1 - 0.065 13.4 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 MbeD/MobD like Ax_dynein_light PF10211.9 EOO02929.1 - 0.14 12.1 6.1 0.3 11.0 6.1 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain GrpE PF01025.19 EOO02929.1 - 1.2 8.8 8.9 2.7 7.6 8.9 1.5 1 0 0 1 1 1 0 GrpE Atg14 PF10186.9 EOO02929.1 - 4 6.4 5.2 7.2 5.6 5.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 EOO02929.1 - 4.3 7.2 8.8 1.8 8.4 5.5 2.0 1 1 0 2 2 2 0 Septum formation initiator Mito_carr PF00153.27 EOO02930.1 - 1.4e-70 233.2 0.6 7.7e-26 89.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 EOO02930.1 - 3.2e-18 63.9 6.8 7.6e-07 28.2 0.2 5.9 6 0 0 6 6 6 4 EF hand EF-hand_6 PF13405.6 EOO02930.1 - 8.1e-18 62.8 0.3 1.9e-06 27.4 0.1 5.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 EOO02930.1 - 9.1e-18 64.5 4.3 4.6e-09 36.6 0.3 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EOO02930.1 - 2.5e-12 45.7 1.9 1.5e-05 24.3 0.3 4.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EOO02930.1 - 2e-11 43.5 3.5 0.0067 16.3 0.1 5.4 5 0 0 5 5 5 4 EF-hand domain pair SMAP PF15477.6 EOO02931.1 - 4.9e-11 43.4 3.7 4.9e-11 43.4 3.7 4.9 2 1 0 2 2 2 1 Small acidic protein family Sec10 PF07393.11 EOO02932.1 - 3.6e-170 567.8 0.0 4.4e-170 567.5 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 EOO02932.1 - 5.8e-08 32.5 0.2 2.6e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EOO02932.1 - 4e-06 26.6 0.1 9.7e-06 25.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain DUF5302 PF17227.2 EOO02932.1 - 0.011 16.8 6.3 0.05 14.6 6.3 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5302) Vps53_N PF04100.12 EOO02932.1 - 0.025 13.6 0.3 0.049 12.6 0.3 1.4 1 0 0 1 1 1 0 Vps53-like, N-terminal F-box_4 PF15966.5 EOO02932.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 F-box K_channel_TID PF07941.11 EOO02932.1 - 1.3 9.6 10.3 3.4 8.2 10.3 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain adh_short_C2 PF13561.6 EOO02933.1 - 6.3e-47 160.1 1.4 1.9e-39 135.6 0.9 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO02933.1 - 4.9e-40 137.1 0.6 6e-40 136.8 0.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO02933.1 - 9.3e-12 45.2 0.5 1.2e-11 44.9 0.5 1.1 1 0 0 1 1 1 1 KR domain AlaDh_PNT_C PF01262.21 EOO02933.1 - 0.0059 15.9 0.2 0.0088 15.4 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 EOO02933.1 - 0.01 15.9 0.4 0.018 15.1 0.2 1.4 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain LA-virus_coat PF09220.10 EOO02933.1 - 0.062 11.9 0.0 0.086 11.5 0.0 1.1 1 0 0 1 1 1 0 L-A virus, major coat protein Epimerase PF01370.21 EOO02933.1 - 0.076 12.5 0.1 0.19 11.1 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 EOO02933.1 - 0.095 13.4 0.0 0.27 12.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain STAG PF08514.11 EOO02934.1 - 1.1e-33 115.5 0.5 1.1e-33 115.5 0.5 2.7 3 0 0 3 3 3 1 STAG domain HEAT_2 PF13646.6 EOO02934.1 - 0.00015 22.1 0.0 0.0082 16.5 0.0 3.0 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 EOO02934.1 - 0.0068 16.6 0.1 22 5.6 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 EOO02934.1 - 0.019 15.0 0.0 0.81 9.7 0.0 3.0 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 B-block_TFIIIC PF04182.12 EOO02934.1 - 0.15 12.2 0.1 0.74 10.0 0.0 2.2 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC SSF PF00474.17 EOO02935.1 - 0.002 17.1 0.1 0.0031 16.4 0.1 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Med5 PF08689.10 EOO02935.1 - 0.024 12.5 0.0 0.026 12.3 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit Med5 Cation_efflux PF01545.21 EOO02936.1 - 7.4e-14 51.9 12.4 9.8e-14 51.5 12.4 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EOO02936.1 - 1.8e-10 40.8 0.2 4.8e-10 39.4 0.2 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PAS_9 PF13426.7 EOO02937.1 - 2.3e-13 50.3 0.0 6.3e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EOO02937.1 - 0.0013 18.7 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold ApoC-I PF04691.12 EOO02937.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) PAS_4 PF08448.10 EOO02937.1 - 0.099 12.9 0.0 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 PAS fold SAP PF02037.27 EOO02938.1 - 5.5e-14 51.5 0.1 9.1e-14 50.8 0.1 1.4 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 EOO02938.1 - 0.00032 20.4 2.0 0.00032 20.4 2.0 2.3 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain HeH PF12949.7 EOO02938.1 - 0.15 11.8 0.9 0.38 10.5 0.0 2.2 2 1 0 2 2 2 0 HeH/LEM domain HEAT_EZ PF13513.6 EOO02939.1 - 3.2e-26 91.4 11.3 1.7e-15 57.1 0.0 10.7 9 1 1 10 10 10 2 HEAT-like repeat HEAT PF02985.22 EOO02939.1 - 4.8e-25 85.5 8.2 0.00048 20.2 0.0 9.7 10 0 0 10 10 9 5 HEAT repeat HEAT_2 PF13646.6 EOO02939.1 - 1e-16 61.1 2.0 1.6e-05 25.2 0.0 7.3 4 3 1 6 6 6 4 HEAT repeats IBN_N PF03810.19 EOO02939.1 - 6e-08 32.5 0.7 5.9e-06 26.1 0.0 4.5 5 1 0 5 5 5 1 Importin-beta N-terminal domain MMS19_C PF12460.8 EOO02939.1 - 6.8e-06 25.4 3.5 0.44 9.6 0.0 4.5 4 1 0 5 5 5 2 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 EOO02939.1 - 3.2e-05 24.5 0.0 3.5 8.3 0.0 5.8 5 1 2 7 7 7 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EOO02939.1 - 0.00019 21.1 0.0 3.1 7.3 0.0 5.1 5 0 0 5 5 5 1 CLASP N terminal Arm PF00514.23 EOO02939.1 - 0.0028 17.7 4.4 0.42 10.7 0.0 5.1 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 EOO02939.1 - 0.024 14.4 0.1 34 4.1 0.0 4.3 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 EOO02939.1 - 0.029 14.5 0.0 1.2 9.3 0.0 3.3 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3437 PF11919.8 EOO02939.1 - 0.14 12.1 0.0 5.8 6.9 0.0 3.6 5 0 0 5 5 5 0 Domain of unknown function (DUF3437) Tti2 PF10521.9 EOO02939.1 - 0.18 11.3 0.4 4.8 6.6 0.0 3.4 4 0 0 4 4 4 0 Tti2 family HEAT_PBS PF03130.16 EOO02939.1 - 0.26 12.1 3.8 53 4.9 0.0 5.2 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat Amidohydro_1 PF01979.20 EOO02941.1 - 5.3e-52 177.2 0.5 6.2e-52 177.0 0.5 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EOO02941.1 - 7.6e-16 58.6 0.2 9.1e-16 58.4 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Xan_ur_permease PF00860.20 EOO02942.1 - 2.3e-56 191.2 28.5 1.1e-55 188.9 28.5 1.8 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 EOO02942.1 - 0.0058 17.0 4.5 0.0058 17.0 4.5 3.9 3 1 1 4 4 4 1 Molybdate transporter of MFS superfamily GATase_4 PF13230.6 EOO02943.1 - 2.3e-17 62.8 0.0 1.7e-14 53.4 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 EOO02943.1 - 1.2e-07 32.0 0.0 2.3e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase domain Dam PF05869.11 EOO02943.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) Bac_rhamnosid6H PF17389.2 EOO02944.1 - 6.2e-11 42.1 0.0 7.5e-09 35.3 0.0 2.2 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF413 PF04219.12 EOO02945.1 - 0.19 11.8 0.0 3 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF F-box-like PF12937.7 EOO02948.1 - 0.0013 18.6 0.4 0.0048 16.8 0.0 2.1 2 0 0 2 2 2 1 F-box-like PIG-Y PF15159.6 EOO02949.1 - 8.4e-23 81.1 9.5 1.2e-22 80.6 9.5 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Nuc_H_symport PF03825.16 EOO02950.1 - 0.012 14.7 5.9 0.013 14.5 4.4 1.6 1 1 1 2 2 2 0 Nucleoside H+ symporter Mito_carr PF00153.27 EOO02951.1 - 6.8e-41 138.1 9.2 5.8e-16 58.2 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 EOO02952.1 - 4e-21 74.6 0.0 5.7e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EOO02952.1 - 4.4e-05 23.1 0.0 6.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TB2_DP1_HVA22 PF03134.19 EOO02953.1 - 1.7e-28 98.3 9.4 1.7e-28 98.3 9.4 1.5 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Bestrophin PF01062.21 EOO02953.1 - 0.004 16.6 0.2 0.0058 16.1 0.2 1.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel UreD PF01774.17 EOO02954.1 - 1.2e-78 263.9 0.1 1.4e-78 263.7 0.1 1.0 1 0 0 1 1 1 1 UreD urease accessory protein Cyclin_N PF00134.23 EOO02955.1 - 8.8e-45 151.5 0.1 5e-44 149.1 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EOO02955.1 - 3e-22 78.9 0.1 6e-21 74.7 0.1 2.6 2 1 0 2 2 2 1 Cyclin, C-terminal domain Imm5 PF14423.6 EOO02955.1 - 0.044 14.0 0.5 0.095 12.9 0.5 1.5 1 0 0 1 1 1 0 Immunity protein Imm5 Branch PF02485.21 EOO02955.1 - 0.094 12.2 0.1 0.7 9.4 0.0 1.9 2 0 0 2 2 2 0 Core-2/I-Branching enzyme MarR_2 PF12802.7 EOO02956.1 - 0.091 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 MarR family FAD_binding_3 PF01494.19 EOO02957.1 - 1e-12 48.0 0.0 1.9e-12 47.1 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EOO02957.1 - 2.5e-12 47.0 2.1 1.8e-07 31.0 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EOO02957.1 - 4.4e-07 29.3 0.7 2e-06 27.2 0.7 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EOO02957.1 - 2.8e-05 23.5 1.1 0.00024 20.4 0.4 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EOO02957.1 - 5e-05 22.2 0.8 0.00066 18.5 0.8 2.0 1 1 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 EOO02957.1 - 0.00024 20.5 0.9 0.047 13.0 0.0 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EOO02957.1 - 0.00036 19.8 0.5 0.00064 18.9 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EOO02957.1 - 0.0018 18.8 0.8 0.22 12.1 0.2 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EOO02957.1 - 0.0028 17.8 0.2 0.0068 16.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EOO02957.1 - 0.074 12.1 0.6 0.18 10.8 0.9 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Cupin_8 PF13621.6 EOO02958.1 - 7.9e-68 228.9 0.0 9.4e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EOO02958.1 - 2.3e-07 30.6 0.2 0.00095 18.7 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein Cupin_3 PF05899.12 EOO02958.1 - 0.067 12.9 0.0 16 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) JmjC PF02373.22 EOO02958.1 - 0.068 13.6 0.0 0.8 10.1 0.0 2.4 2 0 0 2 2 2 0 JmjC domain, hydroxylase GST_C_3 PF14497.6 EOO02959.1 - 6.5e-13 48.7 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EOO02959.1 - 8.4e-13 48.5 0.0 1.6e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EOO02959.1 - 1.9e-12 47.4 0.0 3.2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EOO02959.1 - 2.3e-12 47.0 0.2 6.6e-12 45.5 0.0 1.9 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EOO02959.1 - 8.5e-10 38.8 0.0 1.6e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EOO02959.1 - 1.7e-07 31.1 0.0 3.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2838 PF10998.8 EOO02960.1 - 2e-46 156.8 12.5 2e-46 156.8 12.5 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Tropomyosin_1 PF12718.7 EOO02960.1 - 0.012 15.7 1.5 0.026 14.7 1.5 1.4 1 0 0 1 1 1 0 Tropomyosin like CCCAP PF15964.5 EOO02960.1 - 0.037 12.4 1.3 0.052 11.9 1.3 1.1 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family ApoLp-III PF07464.11 EOO02960.1 - 0.049 13.7 0.8 0.09 12.9 0.8 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 EOO02960.1 - 0.37 10.6 5.9 0.54 10.1 5.0 1.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Val_tRNA-synt_C PF10458.9 EOO02960.1 - 0.51 10.7 5.4 21 5.5 3.8 2.4 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF3584 PF12128.8 EOO02960.1 - 0.79 7.2 4.5 1.1 6.7 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Uso1_p115_C PF04871.13 EOO02960.1 - 3 8.2 5.5 3.8 7.9 3.0 2.0 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region LigB PF02900.18 EOO02961.1 - 3.8e-10 39.3 0.0 1e-09 37.9 0.0 1.7 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase ADH_zinc_N_2 PF13602.6 EOO02962.1 - 9.6e-26 91.4 0.0 2.6e-25 90.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EOO02962.1 - 1.6e-15 57.2 0.1 2.6e-15 56.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EOO02963.1 - 1.5e-21 76.7 0.0 2e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO02963.1 - 4.7e-15 55.8 0.2 6e-15 55.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO02963.1 - 7.9e-05 22.6 0.2 0.00018 21.5 0.2 1.6 1 1 0 1 1 1 1 KR domain Metallophos PF00149.28 EOO02964.1 - 3.4e-18 66.9 1.6 6.3e-18 66.0 1.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EOO02964.1 - 1.5e-06 28.5 0.0 1.1e-05 25.7 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain adh_short_C2 PF13561.6 EOO02965.1 - 1.5e-44 152.3 2.2 4.7e-44 150.7 1.3 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO02965.1 - 3.3e-40 137.7 0.3 5.5e-40 136.9 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO02965.1 - 7.9e-11 42.2 0.8 5.1e-10 39.5 0.7 2.1 2 0 0 2 2 2 1 KR domain Abhydrolase_6 PF12697.7 EOO02965.1 - 2.4e-09 38.1 0.5 2.4e-09 38.1 0.5 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 EOO02965.1 - 0.00017 21.3 0.1 0.052 13.1 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family DUF4325 PF14213.6 EOO02965.1 - 0.12 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) RAMP4 PF06624.12 EOO02966.1 - 1.4e-22 79.5 0.0 1.5e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 YqzE PF14038.6 EOO02966.1 - 0.19 11.8 0.0 0.19 11.8 0.0 2.3 2 1 1 3 3 3 0 YqzE-like protein Abhydrolase_3 PF07859.13 EOO02967.1 - 0.00033 20.6 0.4 0.008 16.0 0.0 2.4 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EOO02967.1 - 0.045 14.3 5.4 0.066 13.8 5.3 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 EOO02967.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DIOX_N PF14226.6 EOO02968.1 - 7.6e-16 58.9 0.0 1.4e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EOO02968.1 - 3.4e-15 56.4 0.0 6.5e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BBE PF08031.12 EOO02968.1 - 0.034 14.3 0.0 0.5 10.5 0.0 2.6 2 0 0 2 2 2 0 Berberine and berberine like Arm PF00514.23 EOO02969.1 - 3.7e-97 315.8 16.8 2.7e-13 49.4 0.1 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EOO02969.1 - 2.6e-27 95.1 1.6 7.1e-27 93.7 1.6 1.8 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 EOO02969.1 - 3.4e-23 80.9 5.2 5e-23 80.4 4.0 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 EOO02969.1 - 4.3e-23 81.4 10.5 7.4e-09 35.9 0.1 6.8 7 0 0 7 7 7 4 HEAT-like repeat HEAT_2 PF13646.6 EOO02969.1 - 1.4e-19 70.2 0.2 9e-09 35.6 0.0 5.3 1 1 2 4 4 4 3 HEAT repeats HEAT PF02985.22 EOO02969.1 - 1.4e-18 65.4 4.0 1.7e-05 24.7 0.0 7.3 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 EOO02969.1 - 3.8e-08 33.1 0.0 0.021 14.3 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like V-ATPase_H_C PF11698.8 EOO02969.1 - 2.7e-05 24.2 0.0 1.7 8.8 0.0 4.5 3 2 2 5 5 5 2 V-ATPase subunit H Adaptin_N PF01602.20 EOO02969.1 - 4.1e-05 22.3 0.0 0.0025 16.4 0.0 2.5 1 1 0 2 2 2 1 Adaptin N terminal region HEAT_PBS PF03130.16 EOO02969.1 - 0.0004 20.8 0.4 0.8 10.6 0.0 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 EOO02969.1 - 0.0006 19.9 0.0 1 9.4 0.0 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Glycos_trans_3N PF02885.17 EOO02969.1 - 0.019 14.8 0.0 7.2 6.5 0.0 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain RICTOR_V PF14668.6 EOO02969.1 - 0.022 15.0 4.5 3.7 7.8 0.1 4.7 3 2 3 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 NopRA1 PF16201.5 EOO02969.1 - 0.025 14.2 0.0 9 5.8 0.0 3.9 1 1 4 5 5 5 0 Nucleolar pre-ribosomal-associated protein 1 NUSAP PF16006.5 EOO02969.1 - 6.5 6.4 6.5 9.4 5.9 6.5 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein TRAP_alpha PF03896.16 EOO02970.1 - 7.8e-07 28.6 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Pkinase PF00069.25 EOO02971.1 - 1.9e-65 220.9 0.0 2.2e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO02971.1 - 5.7e-36 124.1 0.0 8.6e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EOO02971.1 - 0.00011 21.7 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EOO02971.1 - 0.053 12.9 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EOO02971.1 - 0.11 12.4 0.1 0.28 11.1 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family CK2S PF15011.6 EOO02972.1 - 0.036 13.9 0.3 0.31 10.9 0.2 2.2 3 0 0 3 3 3 0 Casein Kinase 2 substrate GCD14 PF08704.10 EOO02972.1 - 0.071 12.8 0.0 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Peptidase_M14 PF00246.24 EOO02973.1 - 5.9e-76 256.0 0.0 7.7e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase POT1PC PF16686.5 EOO02974.1 - 1.8e-52 177.3 0.0 5.5e-52 175.8 0.0 1.9 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 EOO02974.1 - 2.1e-17 63.3 0.1 6.1e-17 61.8 0.0 1.8 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 REPA_OB_2 PF16900.5 EOO02974.1 - 0.0067 16.3 0.3 0.024 14.6 0.0 2.1 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 EOO02974.1 - 0.052 13.5 0.0 2 8.4 0.0 3.2 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Fungal_trans_2 PF11951.8 EOO02976.1 - 9.8e-09 34.5 0.1 1.8e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EOO02976.1 - 9.5e-06 25.6 5.3 1.6e-05 24.9 5.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF2_N PF00176.23 EOO02977.1 - 6.3e-11 41.6 0.0 4.9e-05 22.2 0.0 2.6 1 1 1 2 2 2 2 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 EOO02977.1 - 3.8e-09 36.3 8.5 8e-09 35.2 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EOO02977.1 - 4e-09 36.7 11.2 7.3e-09 35.8 11.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EOO02977.1 - 1.6e-08 34.2 11.8 3.3e-08 33.2 11.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EOO02977.1 - 2.4e-07 30.5 10.2 4.2e-07 29.7 10.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EOO02977.1 - 4.5e-07 29.6 9.3 8.3e-07 28.8 9.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EOO02977.1 - 8.2e-06 25.8 4.8 8.2e-06 25.8 4.8 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EOO02977.1 - 3.5e-05 24.0 8.0 8.2e-05 22.8 8.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EOO02977.1 - 0.00013 21.9 10.8 0.00025 20.9 10.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.31 EOO02977.1 - 0.00035 20.9 0.0 0.0014 19.0 0.0 2.1 2 0 0 2 2 1 1 Helicase conserved C-terminal domain Baculo_IE-1 PF05290.11 EOO02977.1 - 0.0045 16.9 1.1 0.01 15.8 1.1 1.6 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.6 EOO02977.1 - 0.0084 16.3 9.6 0.016 15.3 9.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EOO02977.1 - 0.28 11.0 7.5 0.18 11.6 4.8 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Vps39_2 PF10367.9 EOO02977.1 - 0.32 11.5 5.7 3 8.3 0.9 3.0 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-P11 PF03854.14 EOO02977.1 - 0.73 9.5 5.5 1.9 8.2 5.5 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-ANAPC11 PF12861.7 EOO02977.1 - 1.6 8.9 7.1 3.9 7.6 7.1 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FMN_dh PF01070.18 EOO02978.1 - 2.8e-87 293.0 0.0 3.5e-87 292.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EOO02978.1 - 7.2e-06 25.4 0.3 2.3e-05 23.7 0.3 1.7 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 EOO02978.1 - 2.8e-05 23.7 0.0 4.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 EOO02978.1 - 0.00016 21.1 0.1 0.011 15.0 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EOO02978.1 - 0.00023 20.3 1.4 0.0013 17.8 1.4 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain zf-HC2 PF13490.6 EOO02978.1 - 0.0028 17.8 0.1 2.7 8.3 0.0 3.2 3 0 0 3 3 3 2 Putative zinc-finger DHO_dh PF01180.21 EOO02978.1 - 0.011 15.0 0.4 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 EOO02978.1 - 0.049 13.1 0.0 0.42 10.0 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein WD40 PF00400.32 EOO02979.1 - 3.4e-19 68.8 9.7 0.0001 23.0 0.1 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO02979.1 - 7.7e-09 35.7 2.0 0.0052 17.1 0.1 3.6 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EOO02979.1 - 1.1e-05 25.4 0.1 0.0025 17.7 0.1 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EOO02979.1 - 0.015 14.3 0.0 0.1 11.5 0.0 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Dynamin_N PF00350.23 EOO02980.1 - 1.5e-44 152.0 0.0 3.5e-44 150.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EOO02980.1 - 1.4e-13 50.7 0.1 9e-11 41.5 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EOO02980.1 - 5.9e-05 23.1 0.1 0.00048 20.2 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EOO02980.1 - 0.028 14.8 0.2 0.18 12.2 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain PQ-loop PF04193.14 EOO02981.1 - 1.3e-32 111.4 16.1 2.6e-17 62.3 1.0 2.9 3 0 0 3 3 3 2 PQ loop repeat Colicin_V PF02674.16 EOO02981.1 - 5.8 6.9 12.2 0.15 12.1 4.3 2.2 2 1 1 3 3 3 0 Colicin V production protein AT_hook PF02178.19 EOO02982.1 - 0.74 9.9 46.0 0.23 11.4 1.8 5.4 5 0 0 5 5 5 0 AT hook motif RFX_DNA_binding PF02257.15 EOO02983.1 - 7.7e-28 96.9 0.0 1.7e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EOO02983.1 - 0.18 11.8 0.0 0.56 10.2 0.0 1.8 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Helicase_C PF00271.31 EOO02984.1 - 1.5e-17 64.0 0.0 3.5e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 EOO02984.1 - 1.5e-16 60.6 0.0 1.5e-16 60.6 0.0 2.5 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EOO02984.1 - 4.3e-11 43.0 0.2 1.4e-10 41.4 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EOO02984.1 - 4e-10 39.7 0.2 1.2e-09 38.2 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.22 EOO02984.1 - 3.8e-06 27.2 0.9 1.2e-05 25.5 0.9 2.0 1 0 0 1 1 1 1 RWD domain AAA_22 PF13401.6 EOO02984.1 - 0.00025 21.3 0.4 0.00085 19.6 0.4 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EOO02984.1 - 0.00042 20.4 0.0 0.00098 19.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_29 PF13555.6 EOO02984.1 - 0.0089 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase PF06745.13 EOO02984.1 - 0.016 14.6 0.0 0.042 13.2 0.0 1.7 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 EOO02984.1 - 0.018 14.5 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DND1_DSRM PF14709.7 EOO02984.1 - 0.072 13.4 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 T2SSE PF00437.20 EOO02984.1 - 0.084 11.9 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 EOO02984.1 - 0.21 12.1 0.1 0.21 12.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain ERM PF00769.19 EOO02985.1 - 0.24 11.2 9.1 0.41 10.4 9.1 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TFIIA PF03153.13 EOO02985.1 - 1.1 9.1 14.4 2.7 7.9 14.4 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPRY PF00622.28 EOO02986.1 - 8.8e-18 64.6 0.0 1.3e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 SPRY domain Hydrolase_4 PF12146.8 EOO02987.1 - 2e-53 181.2 0.0 2.3e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EOO02987.1 - 2.4e-12 47.9 1.1 3.4e-12 47.4 1.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EOO02987.1 - 1e-10 41.7 0.0 1.6e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EOO02987.1 - 0.0034 16.9 0.2 0.94 8.9 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family RNA_pol_Rpc4 PF05132.14 EOO02988.1 - 3.9e-29 102.0 0.1 3.9e-29 102.0 0.1 2.1 2 1 0 2 2 2 1 RNA polymerase III RPC4 MRPL52 PF18699.1 EOO02988.1 - 0.081 13.1 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Mitoribosomal protein mL52 Serglycin PF04360.12 EOO02988.1 - 2 8.4 4.7 22 5.0 4.5 2.2 2 0 0 2 2 2 0 Serglycin SMC_N PF02463.19 EOO02989.1 - 1.1e-48 165.6 37.4 4.3e-47 160.4 37.4 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EOO02989.1 - 7.3e-26 90.8 0.0 5.3e-25 88.0 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EOO02989.1 - 5.2e-13 50.0 15.2 5.2e-13 50.0 15.2 6.6 3 2 1 5 5 5 2 AAA domain AAA_21 PF13304.6 EOO02989.1 - 4.1e-09 36.7 0.6 4.8e-05 23.3 0.1 3.8 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EOO02989.1 - 2.9e-08 33.3 0.0 5.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EOO02989.1 - 3.7e-07 30.2 15.9 3.7e-07 30.2 15.9 4.4 2 2 2 4 4 4 1 AAA ATPase domain SbcCD_C PF13558.6 EOO02989.1 - 0.012 15.8 0.0 0.091 13.0 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Spc7 PF08317.11 EOO02989.1 - 0.12 11.3 143.1 0.027 13.3 22.9 7.8 3 2 5 8 8 8 0 Spc7 kinetochore protein ABC_tran PF00005.27 EOO02989.1 - 0.72 10.4 0.0 0.72 10.4 0.0 7.0 5 3 0 5 5 5 0 ABC transporter ATG16 PF08614.11 EOO02989.1 - 8.8 6.5 121.7 0.43 10.8 20.5 6.3 4 1 1 5 5 5 0 Autophagy protein 16 (ATG16) Y_phosphatase3 PF13350.6 EOO02993.1 - 5.4e-42 144.3 0.0 1.3e-41 143.1 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EOO02993.1 - 3.4e-06 26.8 0.0 1e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 EOO02993.1 - 0.0054 16.5 0.0 0.072 12.9 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 EOO02993.1 - 0.0078 15.2 0.1 0.016 14.2 0.0 1.4 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 EOO02993.1 - 0.0084 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CHZ PF09649.10 EOO02994.1 - 0.001 18.5 0.1 0.0033 16.9 0.1 1.8 1 0 0 1 1 1 1 Histone chaperone domain CHZ Zn_clus PF00172.18 EOO02994.1 - 0.0012 18.9 12.5 0.0022 18.1 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HE PF16278.5 EOO02995.1 - 8.7e-16 58.1 0.1 2.1e-15 56.9 0.1 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 EOO02995.1 - 9.2e-16 58.3 9.1 2.8e-14 53.6 9.1 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EOO02995.1 - 1.6e-14 54.4 3.0 5.5e-14 52.7 3.0 1.8 1 1 0 1 1 1 1 HIT domain Aldedh PF00171.22 EOO02996.1 - 0.0079 14.7 0.1 0.014 13.9 0.1 1.5 1 1 0 1 1 1 1 Aldehyde dehydrogenase family I_LWEQ PF01608.17 EOO02996.1 - 6.1 7.1 8.3 9.7 6.4 0.3 2.7 3 0 0 3 3 3 0 I/LWEQ domain Acetyltransf_1 PF00583.25 EOO02997.1 - 4.2e-15 56.0 0.0 5.6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EOO02997.1 - 5.6e-11 42.5 0.0 1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EOO02997.1 - 6.2e-11 42.6 0.0 8.8e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EOO02997.1 - 3e-07 30.3 0.0 4.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EOO02997.1 - 7.3e-05 22.9 0.1 9.8e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EOO02997.1 - 0.00017 21.7 0.1 0.00056 20.1 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain N2227 PF07942.12 EOO02998.1 - 7.4e-103 343.4 0.0 8.8e-103 343.2 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 EOO02998.1 - 0.00021 21.2 0.0 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO02998.1 - 0.00031 21.4 0.0 0.0018 18.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO02998.1 - 0.00079 20.0 0.0 0.0062 17.2 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO02998.1 - 0.096 12.5 0.0 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 EOO02998.1 - 0.12 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Peptidase_M20 PF01546.28 EOO02999.1 - 6.1e-21 75.1 0.0 6.4e-21 75.0 0.0 1.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EOO02999.1 - 9.4e-13 48.0 0.2 2.4e-12 46.8 0.2 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain NAD_binding_4 PF07993.12 EOO03000.1 - 1.6e-29 102.9 0.0 2.3e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EOO03000.1 - 3.2e-13 49.7 0.0 5.5e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO03000.1 - 1.2e-06 28.2 0.0 2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase PP-binding PF00550.25 EOO03000.1 - 2.1e-05 24.8 0.1 0.00018 21.8 0.1 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding PF00501.28 EOO03000.1 - 0.011 14.4 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme Sugar_tr PF00083.24 EOO03001.1 - 3.5e-78 263.5 13.3 4.7e-78 263.0 13.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO03001.1 - 1.1e-16 60.8 20.5 1.1e-16 60.8 20.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 EOO03001.1 - 3.9e-07 29.0 9.3 0.00079 18.1 2.8 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein KR PF08659.10 EOO03002.1 - 4.6e-58 196.1 1.9 6.5e-58 195.6 0.2 2.1 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 EOO03002.1 - 4.6e-49 167.6 0.7 1.8e-48 165.7 0.2 2.3 2 1 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.6 EOO03002.1 - 3.6e-46 157.8 0.1 5.8e-46 157.1 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EOO03002.1 - 1.1e-33 115.7 0.1 3.2e-33 114.2 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EOO03002.1 - 8.1e-27 94.4 0.1 5.2e-23 81.9 0.0 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ADH_zinc_N_2 PF13602.6 EOO03002.1 - 6.7e-18 66.0 0.0 5e-17 63.2 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EOO03002.1 - 4.3e-16 59.4 0.2 8.7e-14 51.9 0.2 3.0 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 EOO03002.1 - 2.4e-13 50.2 0.0 1e-12 48.1 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EOO03002.1 - 1.5e-11 44.1 0.1 4.1e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03002.1 - 4.6e-08 32.9 0.0 9.6e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 EOO03002.1 - 2.6e-07 30.9 0.1 5.8e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EOO03002.1 - 0.00047 20.0 0.3 0.00098 19.0 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain VbhA PF18495.1 EOO03002.1 - 0.19 11.6 1.3 17 5.4 0.3 3.0 2 0 0 2 2 2 0 Antitoxin VbhA Sugar_tr PF00083.24 EOO03003.1 - 1.6e-64 218.4 17.1 1.9e-64 218.2 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO03003.1 - 3.9e-19 68.8 18.7 2.2e-10 40.0 4.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CRCB PF02537.15 EOO03003.1 - 1.8 8.9 10.4 0.69 10.3 2.9 3.0 2 1 1 3 3 3 0 CrcB-like protein, Camphor Resistance (CrcB) Peptidase_C12 PF01088.21 EOO03004.1 - 3.5e-57 193.6 0.0 4e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Phage_30_8 PF06019.11 EOO03004.1 - 0.086 12.8 0.1 7.9 6.4 0.1 2.1 2 0 0 2 2 2 0 Phage GP30.8 protein CN_hydrolase PF00795.22 EOO03005.1 - 2.4e-47 161.5 0.0 2.8e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_43 PF04616.14 EOO03006.1 - 8e-55 186.2 4.6 1.2e-54 185.6 4.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EOO03006.1 - 1.4e-08 34.8 0.0 3e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_2_C PF02836.17 EOO03008.1 - 1.3e-97 326.6 0.2 1.6e-97 326.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 EOO03008.1 - 4.4e-13 49.9 0.2 9.9e-13 48.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EOO03008.1 - 0.00089 19.2 0.1 0.0069 16.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain NAD_binding_6 PF08030.12 EOO03009.1 - 2.6e-31 108.8 0.0 4.4e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EOO03009.1 - 7.6e-21 74.2 0.4 2.4e-20 72.7 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 EOO03009.1 - 1.8e-17 63.6 12.7 1.8e-17 63.6 12.7 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component Carn_acyltransf PF00755.20 EOO03010.1 - 1.4e-103 347.5 0.0 1.9e-103 347.1 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase KR PF08659.10 EOO03010.1 - 2.5e-48 164.4 0.2 4.9e-48 163.4 0.2 1.6 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 EOO03010.1 - 1e-18 68.7 0.0 7.2e-18 65.9 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EOO03010.1 - 8.9e-09 35.1 0.2 1.8e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 EOO03010.1 - 1.1e-08 35.3 0.9 3.4e-08 33.7 0.9 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 EOO03010.1 - 8.4e-07 29.0 0.0 4.2e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 EOO03010.1 - 0.0014 18.3 0.1 0.0029 17.2 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_2 PF03446.15 EOO03010.1 - 0.0022 18.2 0.2 0.0062 16.7 0.2 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.19 EOO03010.1 - 0.02 13.9 0.1 0.23 10.4 0.0 2.3 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EOO03010.1 - 0.028 13.9 0.1 0.049 13.1 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DNA_pol3_delt_C PF14840.6 EOO03010.1 - 0.083 13.2 0.0 0.28 11.5 0.0 1.9 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term Abhydrolase_6 PF12697.7 EOO03011.1 - 1.3e-12 48.8 1.1 1.3e-12 48.8 1.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family WSC PF01822.19 EOO03011.1 - 1.4e-05 25.2 9.3 3.1e-05 24.1 9.3 1.6 1 0 0 1 1 1 1 WSC domain Hydrolase_4 PF12146.8 EOO03011.1 - 0.0021 17.3 0.0 0.0049 16.2 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EOO03011.1 - 0.04 13.6 0.0 0.071 12.7 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF3089 PF11288.8 EOO03011.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) XPG_N PF00752.17 EOO03012.1 - 1e-30 106.2 0.0 3e-30 104.7 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EOO03012.1 - 7.5e-30 103.1 2.1 1.6e-29 102.1 0.0 2.3 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 EOO03012.1 - 2.7e-05 24.7 1.1 0.00018 22.1 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold AAA_23 PF13476.6 EOO03012.1 - 0.07 13.6 6.3 0.039 14.5 3.9 1.8 2 0 0 2 2 2 0 AAA domain HXXSHH PF07586.11 EOO03012.1 - 0.27 10.8 3.5 0.49 9.9 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Pkinase_Tyr PF07714.17 EOO03013.1 - 0.0002 20.7 0.0 0.1 11.9 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EOO03013.1 - 0.0014 18.1 0.0 0.0036 16.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain N-SET PF11764.8 EOO03013.1 - 0.16 12.0 0.5 0.37 10.9 0.5 1.5 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N DUF3619 PF12279.8 EOO03013.1 - 1.7 9.0 5.6 9.7 6.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3619) MFS_1 PF07690.16 EOO03014.1 - 2e-28 99.4 22.5 2.4e-28 99.1 22.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MotA_ExbB PF01618.16 EOO03014.1 - 0.042 13.6 0.1 0.085 12.6 0.1 1.5 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family adh_short PF00106.25 EOO03015.1 - 1.7e-21 76.6 0.1 8.8e-21 74.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03015.1 - 1.5e-12 47.6 0.0 2.1e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO03015.1 - 2.1e-08 34.3 0.1 2.9e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO03015.1 - 8.4e-05 22.1 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO03015.1 - 9.6e-05 21.9 0.1 0.00028 20.4 0.1 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase UQ_con PF00179.26 EOO03016.1 - 9.9e-43 145.1 0.0 3.7e-42 143.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EOO03016.1 - 0.0035 17.0 0.0 0.004 16.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EOO03016.1 - 0.029 14.7 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EOO03016.1 - 0.041 13.8 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain CN_hydrolase PF00795.22 EOO03017.1 - 3.4e-45 154.4 0.0 4.2e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF3632 PF12311.8 EOO03018.1 - 8.4e-21 75.2 0.4 9.7e-21 75.0 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DAO PF01266.24 EOO03019.1 - 2.3e-45 155.7 5.1 2.6e-45 155.6 5.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EOO03019.1 - 5.7e-09 35.6 0.2 0.0029 16.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EOO03019.1 - 1.9e-07 31.2 1.4 0.00058 19.9 0.5 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 EOO03019.1 - 2.9e-06 26.7 4.5 0.0079 15.3 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EOO03019.1 - 5.6e-06 25.6 1.6 0.037 13.1 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 EOO03019.1 - 1.2e-05 25.4 1.3 2.7e-05 24.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EOO03019.1 - 0.0001 21.3 3.4 0.014 14.2 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 EOO03019.1 - 0.00014 21.3 0.2 0.28 10.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EOO03019.1 - 0.00019 21.8 0.0 0.00032 21.1 0.0 1.5 1 1 0 1 1 1 1 Putative NAD(P)-binding Amino_oxidase PF01593.24 EOO03019.1 - 0.00053 19.4 0.1 0.0013 18.1 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EOO03019.1 - 0.0012 17.6 2.9 0.011 14.4 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EOO03019.1 - 0.014 14.8 2.5 0.067 12.5 2.5 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EOO03019.1 - 0.017 14.2 4.6 0.088 11.9 4.6 2.0 1 1 0 1 1 1 0 FAD binding domain THF_DHG_CYH_C PF02882.19 EOO03019.1 - 0.019 14.3 0.6 0.039 13.3 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox PF00070.27 EOO03019.1 - 0.02 15.4 0.7 0.02 15.4 0.7 2.6 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 EOO03019.1 - 0.024 13.2 0.2 0.18 10.3 0.1 1.9 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) K_oxygenase PF13434.6 EOO03019.1 - 0.032 13.4 0.2 0.19 10.9 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EOO03019.1 - 0.081 12.2 0.8 1.8 7.7 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 EOO03019.1 - 0.087 12.5 3.6 0.068 12.8 1.3 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 EOO03019.1 - 0.089 12.1 0.3 0.089 12.1 0.3 2.3 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EOO03019.1 - 0.094 12.6 0.7 0.17 11.8 0.7 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 EOO03020.1 - 2.4e-22 79.3 0.0 4.5e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EOO03020.1 - 3.3e-10 41.1 0.0 8.7e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EOO03020.1 - 1.4e-09 37.8 0.0 3.6e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase Acyl-CoA_dh_1 PF00441.24 EOO03021.1 - 4.1e-42 143.9 0.5 6.1e-42 143.4 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EOO03021.1 - 1.1e-22 80.0 0.1 2e-22 79.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 EOO03021.1 - 6.9e-20 71.0 0.3 1.4e-19 70.0 0.3 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 EOO03021.1 - 2.3e-18 66.9 0.0 5.2e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EOO03021.1 - 7.3e-09 36.0 0.0 1.7e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain adh_short PF00106.25 EOO03022.1 - 8.7e-29 100.4 0.0 1.1e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03022.1 - 2e-21 76.6 0.0 2.4e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO03022.1 - 1.5e-08 34.8 0.0 2.1e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EOO03022.1 - 1.3e-05 25.2 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Pkinase PF00069.25 EOO03023.1 - 3.8e-43 147.7 0.0 4.9e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO03023.1 - 6.7e-24 84.6 0.0 9e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EOO03023.1 - 0.00017 21.0 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EOO03023.1 - 0.07 12.5 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bac_luciferase PF00296.20 EOO03024.1 - 2.1e-68 231.1 0.0 2.5e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase p450 PF00067.22 EOO03025.1 - 1.5e-53 182.2 0.0 8.9e-53 179.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 FixQ PF05545.11 EOO03025.1 - 0.11 12.4 0.3 0.26 11.3 0.3 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Acyl-CoA_dh_N PF02771.16 EOO03026.1 - 5.2e-26 91.5 0.1 1.2e-25 90.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EOO03026.1 - 1.7e-22 80.3 1.0 2.7e-22 79.6 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EOO03026.1 - 3.1e-18 65.8 0.0 6.6e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EOO03026.1 - 1.2e-05 25.6 0.8 2.2e-05 24.8 0.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_S8 PF00082.22 EOO03027.1 - 5e-30 104.8 4.6 7.3e-30 104.3 4.6 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EOO03027.1 - 0.056 14.1 0.0 0.092 13.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase inhibitor I9 adh_short PF00106.25 EOO03028.1 - 1.4e-41 142.1 0.0 1.9e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03028.1 - 1.3e-25 90.3 0.0 1.9e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO03028.1 - 2.3e-07 30.9 0.0 3.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EOO03028.1 - 0.17 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Ank_4 PF13637.6 EOO03029.1 - 1.6e-20 73.2 0.1 3.8e-07 30.5 0.0 4.9 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EOO03029.1 - 3e-18 66.2 0.0 1.3e-06 28.9 0.2 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 EOO03029.1 - 1.8e-17 62.9 4.8 1.7e-06 28.2 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EOO03029.1 - 1.1e-15 56.1 0.7 1.6e-06 28.0 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EOO03029.1 - 6.7e-15 55.0 1.1 0.00013 22.2 0.0 4.3 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Cys_Met_Meta_PP PF01053.20 EOO03030.1 - 1.4e-125 418.8 0.0 1.6e-125 418.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EOO03030.1 - 4.3e-11 42.4 0.1 6.7e-11 41.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EOO03030.1 - 5.8e-10 39.0 0.1 1.4e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EOO03030.1 - 7.2e-09 35.3 0.0 1.1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EOO03030.1 - 1.6e-05 24.3 0.0 2.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 EOO03030.1 - 0.0021 16.8 0.0 0.003 16.3 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS GDC-P PF02347.16 EOO03030.1 - 0.0059 15.5 0.0 0.0093 14.8 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 EOO03030.1 - 0.088 11.3 0.0 0.17 10.4 0.0 1.4 1 0 0 1 1 1 0 Methionine gamma-lyase CPSase_L_D2 PF02786.17 EOO03030.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain AA_permease_2 PF13520.6 EOO03031.1 - 2.1e-55 188.3 50.8 2.6e-55 188.0 50.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EOO03031.1 - 7e-30 104.0 45.1 8.8e-30 103.7 45.1 1.0 1 0 0 1 1 1 1 Amino acid permease SLATT_5 PF18160.1 EOO03031.1 - 4 6.7 12.4 0.035 13.4 3.1 2.3 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF4191 PF13829.6 EOO03031.1 - 9.2 5.5 6.8 4.2 6.6 0.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4191) Pyr_redox_2 PF07992.14 EOO03032.1 - 6.4e-05 22.3 1.7 0.062 12.5 0.1 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EOO03032.1 - 0.01 16.4 0.1 0.46 11.1 0.1 2.3 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EOO03032.1 - 0.022 14.0 0.9 0.46 9.7 0.0 2.7 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FlxA PF14282.6 EOO03033.1 - 0.072 13.1 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 FlxA-like protein R3H PF01424.22 EOO03033.1 - 0.1 12.6 0.1 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 R3H domain Baculo_PEP_C PF04513.12 EOO03033.1 - 0.11 12.6 0.1 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tweety PF04906.13 EOO03033.1 - 0.19 10.4 0.2 0.26 9.9 0.2 1.1 1 0 0 1 1 1 0 Tweety Hemagglutinin PF00509.18 EOO03033.1 - 0.27 9.6 0.1 0.4 9.0 0.1 1.2 1 0 0 1 1 1 0 Haemagglutinin DUF16 PF01519.16 EOO03033.1 - 6.2 7.4 6.3 5.6 7.5 3.7 2.2 2 1 0 2 2 2 0 Protein of unknown function DUF16 ABC_tran PF00005.27 EOO03034.1 - 1.7e-11 44.8 0.0 4e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EOO03034.1 - 5.9e-06 25.9 0.0 9.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EOO03034.1 - 0.018 15.2 0.2 0.66 10.2 0.2 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 EOO03034.1 - 0.023 13.5 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class KIX_2 PF16987.5 EOO03035.1 - 0.00078 19.4 4.1 0.005 16.8 0.4 3.8 2 0 0 2 2 2 1 KIX domain Glyco_hydro_1 PF00232.18 EOO03036.1 - 2.8e-111 372.2 0.0 3.3e-111 371.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Voltage_CLC PF00654.20 EOO03037.1 - 4.9e-90 302.3 22.0 4.9e-90 302.3 22.0 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel Creatinase_N_2 PF16189.5 EOO03038.1 - 1.3e-53 181.4 1.1 6.4e-52 175.9 0.0 3.1 4 0 0 4 4 4 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EOO03038.1 - 1.6e-42 145.6 0.0 2.3e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 EOO03038.1 - 9.1e-24 83.3 0.3 2.3e-23 82.0 0.3 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EOO03038.1 - 3.2e-21 76.4 0.1 6.8e-18 65.6 0.0 2.7 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain WD40 PF00400.32 EOO03039.1 - 0.00099 19.9 0.3 0.0084 16.9 0.8 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat P5CR_dimer PF14748.6 EOO03040.1 - 2.4e-34 117.7 1.2 3.7e-34 117.1 1.2 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation Neurochondrin PF05536.11 EOO03041.1 - 1.3e-90 304.6 2.6 1.6e-90 304.3 2.6 1.1 1 0 0 1 1 1 1 Neurochondrin RIX1 PF08167.12 EOO03041.1 - 0.051 13.3 0.0 0.8 9.4 0.0 2.6 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis INTS5_C PF14838.6 EOO03041.1 - 0.054 12.1 0.3 0.97 8.0 0.0 2.1 2 0 0 2 2 2 0 Integrator complex subunit 5 C-terminus Pkinase PF00069.25 EOO03042.1 - 3.5e-19 69.2 0.0 6.1e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain FHA PF00498.26 EOO03042.1 - 4.4e-12 46.2 0.0 1.7e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 FHA domain Pkinase_Tyr PF07714.17 EOO03042.1 - 3.1e-08 33.2 0.0 4.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Whi5 PF08528.11 EOO03043.1 - 9.6e-11 41.1 0.1 1.6e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 Whi5 like CTK3 PF12243.8 EOO03044.1 - 1.3e-51 173.7 0.4 1.9e-51 173.2 0.4 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EOO03044.1 - 9.1e-21 73.8 8.5 9.1e-21 73.8 8.5 1.9 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus Rcd1 PF04078.13 EOO03044.1 - 0.063 12.6 0.1 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like Troponin PF00992.20 EOO03044.1 - 0.8 10.0 6.8 37 4.6 0.2 3.3 3 0 0 3 3 3 0 Troponin Ribosomal_S10 PF00338.22 EOO03045.1 - 8.5e-25 86.8 0.0 1.8e-24 85.8 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e AAA_5 PF07728.14 EOO03046.1 - 5.1e-53 178.8 2.0 5.6e-22 78.2 0.0 4.5 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EOO03046.1 - 4.7e-15 56.4 7.1 7.6e-07 29.7 0.5 4.5 3 1 1 4 4 4 3 AAA ATPase domain AAA_lid_7 PF17867.1 EOO03046.1 - 6.5e-15 55.2 1.2 1.2e-12 47.9 1.2 2.5 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_7 PF12775.7 EOO03046.1 - 4e-14 52.5 0.2 2.3e-06 27.3 0.0 3.6 4 0 0 4 4 3 3 P-loop containing dynein motor region AAA PF00004.29 EOO03046.1 - 6.1e-14 52.6 0.2 0.00041 20.8 0.0 4.0 4 0 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 EOO03046.1 - 6.1e-12 45.5 0.0 8.4e-06 25.7 0.0 4.2 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EOO03046.1 - 1.7e-11 44.1 0.2 0.0024 17.6 0.0 3.8 4 1 0 4 4 3 2 Sigma-54 interaction domain AAA_22 PF13401.6 EOO03046.1 - 5.1e-11 43.0 2.9 0.00039 20.7 0.2 4.4 4 1 0 4 4 3 2 AAA domain AAA_6 PF12774.7 EOO03046.1 - 6.9e-11 41.7 0.0 0.00012 21.2 0.0 3.7 3 1 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region RuvB_N PF05496.12 EOO03046.1 - 1.1e-10 41.5 0.1 0.0015 18.3 0.0 4.3 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EOO03046.1 - 3.8e-10 39.9 0.0 0.00028 20.9 0.0 4.5 5 0 0 5 5 4 2 AAA domain AAA_18 PF13238.6 EOO03046.1 - 4e-10 40.3 0.6 0.0029 18.1 0.0 3.9 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 EOO03046.1 - 5e-10 38.9 0.0 0.00051 19.2 0.0 3.5 3 0 0 3 3 3 2 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 EOO03046.1 - 6e-09 36.1 0.0 2.2e-05 24.6 0.0 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_30 PF13604.6 EOO03046.1 - 2.5e-08 33.9 0.2 0.18 11.5 0.1 4.5 3 2 0 3 3 3 2 AAA domain TsaE PF02367.17 EOO03046.1 - 3.9e-08 33.3 0.0 0.037 14.0 0.0 3.5 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EOO03046.1 - 1.5e-07 31.7 0.3 0.017 15.5 0.0 3.7 3 0 0 3 3 3 1 RNA helicase Dynein_heavy PF03028.15 EOO03046.1 - 7.5e-07 29.3 0.0 0.00066 19.8 0.0 2.9 2 1 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain ABC_tran PF00005.27 EOO03046.1 - 9.9e-07 29.4 1.8 0.00054 20.5 0.0 3.8 4 0 0 4 4 3 1 ABC transporter Mg_chelatase PF01078.21 EOO03046.1 - 2.1e-06 27.3 0.3 9 5.6 0.0 5.4 5 1 0 5 5 5 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EOO03046.1 - 2.2e-06 27.1 2.4 0.15 11.4 0.0 4.6 5 0 0 5 5 4 1 Zeta toxin NACHT PF05729.12 EOO03046.1 - 4.7e-06 26.6 0.3 0.38 10.7 0.0 3.6 3 0 0 3 3 3 2 NACHT domain AAA_28 PF13521.6 EOO03046.1 - 7.3e-06 26.3 0.7 0.56 10.4 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.6 EOO03046.1 - 1.4e-05 25.3 0.1 1.5 8.9 0.0 4.0 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 EOO03046.1 - 2.1e-05 24.5 0.0 0.034 14.0 0.0 3.3 4 0 0 4 4 3 1 Rad17 P-loop domain IstB_IS21 PF01695.17 EOO03046.1 - 2.2e-05 24.3 0.0 1.4 8.6 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_29 PF13555.6 EOO03046.1 - 2.7e-05 23.8 0.0 5.3 6.9 0.0 3.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 EOO03046.1 - 2.9e-05 23.8 0.1 0.0097 15.7 0.0 3.3 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 EOO03046.1 - 0.00013 21.4 0.3 0.93 8.9 0.0 3.1 3 0 0 3 3 3 2 Bacterial TniB protein RsgA_GTPase PF03193.16 EOO03046.1 - 0.00014 21.8 0.0 0.65 9.9 0.0 3.4 3 0 0 3 3 3 1 RsgA GTPase ResIII PF04851.15 EOO03046.1 - 0.00015 21.8 0.0 0.35 10.8 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 EOO03046.1 - 0.00018 21.3 0.2 4 7.1 0.0 4.4 4 1 0 4 4 4 0 AAA domain ATPase_2 PF01637.18 EOO03046.1 - 0.00021 21.3 0.0 0.5 10.2 0.0 3.3 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EOO03046.1 - 0.00024 20.8 0.1 0.14 11.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain dNK PF01712.19 EOO03046.1 - 0.00033 20.6 0.7 3.7 7.4 0.0 3.4 3 0 0 3 3 3 0 Deoxynucleoside kinase AAA_2 PF07724.14 EOO03046.1 - 0.00041 20.5 0.0 0.43 10.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EOO03046.1 - 0.0005 19.4 0.0 0.16 11.1 0.0 3.1 3 0 0 3 3 3 1 TIP49 P-loop domain SRP54 PF00448.22 EOO03046.1 - 0.00057 19.6 0.2 0.33 10.6 0.0 3.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 EOO03046.1 - 0.00058 19.9 0.4 10 6.3 0.0 3.6 3 0 0 3 3 3 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 EOO03046.1 - 0.00089 19.2 0.9 2.2 8.2 0.1 3.5 3 0 0 3 3 3 1 NTPase AAA_19 PF13245.6 EOO03046.1 - 0.0013 19.0 3.7 3.3 8.0 0.0 4.1 4 1 0 5 5 3 0 AAA domain KAP_NTPase PF07693.14 EOO03046.1 - 0.0022 17.3 0.0 1.1 8.4 0.0 3.0 3 0 0 3 3 3 1 KAP family P-loop domain Roc PF08477.13 EOO03046.1 - 0.0029 17.8 0.2 11 6.3 0.0 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATPase PF06745.13 EOO03046.1 - 0.0035 16.7 0.0 0.91 8.8 0.0 3.0 3 0 0 3 3 3 1 KaiC DEAD PF00270.29 EOO03046.1 - 0.0038 17.0 0.6 0.99 9.1 0.0 3.6 5 1 0 5 5 3 1 DEAD/DEAH box helicase DUF815 PF05673.13 EOO03046.1 - 0.0049 16.1 0.1 0.5 9.5 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 EOO03046.1 - 0.006 16.4 0.1 7.2 6.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 EOO03046.1 - 0.0069 15.6 0.0 8.4 5.5 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain SRPRB PF09439.10 EOO03046.1 - 0.0091 15.4 0.1 6.4 6.2 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit cobW PF02492.19 EOO03046.1 - 0.012 15.2 0.5 17 5.0 0.0 3.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 EOO03046.1 - 0.013 15.3 0.1 5.1 6.8 0.0 3.5 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EOO03046.1 - 0.016 14.7 0.0 0.94 8.9 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein CLP1_P PF16575.5 EOO03046.1 - 0.03 14.1 0.1 6.5 6.5 0.0 2.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP_bind_1 PF03029.17 EOO03046.1 - 0.032 14.0 2.7 1.4 8.6 0.1 3.5 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 EOO03046.1 - 0.033 13.3 0.0 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit DAP3 PF10236.9 EOO03046.1 - 0.033 13.3 0.1 10 5.2 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_17 PF13207.6 EOO03046.1 - 0.035 14.5 3.5 0.42 11.0 0.2 3.4 2 1 0 2 2 2 0 AAA domain CPT PF07931.12 EOO03046.1 - 0.047 13.5 1.3 7.7 6.3 0.0 4.0 4 1 1 5 5 5 0 Chloramphenicol phosphotransferase-like protein tRNA_lig_kinase PF08303.11 EOO03046.1 - 0.097 12.8 0.0 0.53 10.4 0.0 2.3 2 1 1 3 3 1 0 tRNA ligase kinase domain Cytidylate_kin PF02224.18 EOO03046.1 - 0.11 12.2 0.0 20 4.8 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase AAA_23 PF13476.6 EOO03046.1 - 0.18 12.3 9.3 2.4 8.6 0.1 3.9 4 1 0 4 4 3 0 AAA domain FeoB_N PF02421.18 EOO03046.1 - 0.28 10.7 0.9 23 4.5 0.1 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B Thymidylate_kin PF02223.17 EOO03046.1 - 0.5 10.0 4.3 1.3 8.7 0.0 3.5 5 0 0 5 5 4 0 Thymidylate kinase Xpo1 PF08389.12 EOO03047.1 - 2.8e-38 131.3 2.6 5e-37 127.2 0.0 3.6 3 1 1 4 4 4 1 Exportin 1-like protein HEAT PF02985.22 EOO03047.1 - 1.3e-05 25.1 0.0 7.6 7.1 0.0 5.2 4 1 1 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 EOO03047.1 - 0.0089 16.5 0.8 27 5.4 0.1 4.7 5 0 0 5 5 5 1 HEAT-like repeat GUN4 PF05419.12 EOO03047.1 - 0.046 13.8 0.9 0.11 12.6 0.1 2.0 2 0 0 2 2 2 0 GUN4-like FAD_binding_7 PF03441.14 EOO03048.1 - 4.1e-73 245.2 0.2 6.1e-73 244.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EOO03048.1 - 4.1e-33 114.7 0.0 1e-32 113.4 0.0 1.6 2 0 0 2 2 2 1 DNA photolyase DNA_ligase_A_M PF01068.21 EOO03049.1 - 4.8e-61 206.0 1.0 8.2e-49 166.0 0.3 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EOO03049.1 - 1.1e-44 152.8 0.0 3e-44 151.4 0.0 1.8 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EOO03049.1 - 1.6e-28 99.2 0.7 4.8e-28 97.7 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EOO03049.1 - 3.5e-05 24.2 0.2 5.8e-05 23.5 0.2 1.4 1 0 0 1 1 1 1 RNA ligase GFA PF04828.14 EOO03050.1 - 0.0033 17.7 0.0 0.006 16.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Sec15 PF04091.12 EOO03051.1 - 1.7e-114 382.5 3.0 4.3e-114 381.2 3.0 1.7 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.6 EOO03051.1 - 0.0042 16.8 4.3 0.012 15.3 4.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF3510 PF12022.8 EOO03051.1 - 0.01 16.2 4.1 3 8.3 0.2 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) Spc29 PF17082.5 EOO03051.1 - 0.59 9.9 6.4 0.21 11.4 1.3 2.5 2 1 1 3 3 3 0 Spindle Pole Component 29 Sec8_exocyst PF04048.14 EOO03051.1 - 1.1 9.2 11.7 0.087 12.7 3.3 3.1 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain ApoLp-III PF07464.11 EOO03051.1 - 2.5 8.2 8.6 0.97 9.5 4.5 2.4 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Seryl_tRNA_N PF02403.22 EOO03051.1 - 5.2 7.4 8.3 36 4.7 0.0 3.6 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Peptidase_M18 PF02127.15 EOO03052.1 - 1.3e-172 574.5 0.0 7e-172 572.1 0.0 1.8 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EOO03052.1 - 5.7e-06 25.6 0.0 0.0015 17.6 0.0 2.7 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Hat1_N PF10394.9 EOO03053.1 - 6.5e-50 169.5 0.0 1.2e-49 168.6 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.7 EOO03053.1 - 0.029 14.3 0.0 0.082 12.8 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EOO03053.1 - 0.063 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family tRNA-synt_1b PF00579.25 EOO03054.1 - 1.4e-55 188.7 0.0 1.7e-33 116.2 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (W and Y) Voldacs PF03517.13 EOO03054.1 - 0.017 15.3 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling E1_dh PF00676.20 EOO03055.1 - 2.3e-112 374.8 0.1 2.8e-112 374.5 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EOO03055.1 - 0.0019 17.5 0.3 0.0034 16.6 0.1 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase SSrecog PF03531.14 EOO03056.1 - 4.7e-30 103.3 0.7 1.5e-29 101.7 0.0 2.3 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 EOO03056.1 - 6.6e-30 103.4 0.1 2.2e-28 98.5 0.0 2.6 2 0 0 2 2 2 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 EOO03056.1 - 1e-22 80.3 0.1 9.9e-22 77.2 0.0 2.6 4 0 0 4 4 4 1 Histone chaperone Rttp106-like RNA_polI_A34 PF08208.11 EOO03056.1 - 2.6 8.1 11.7 3.4 7.7 9.8 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2201_N PF13203.6 EOO03056.1 - 9.2 5.8 8.8 0.95 9.0 0.0 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain zf-C2H2_assoc PF16606.5 EOO03057.1 - 0.069 13.4 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Unstructured conserved, between two C2H2-type zinc-fingers RRM_2 PF04059.12 EOO03058.1 - 7.7e-35 119.0 0.2 1.8e-34 117.8 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif 2 EutA PF06277.11 EOO03058.1 - 0.054 12.3 0.1 0.085 11.7 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA RRM_1 PF00076.22 EOO03059.1 - 1.2e-37 127.5 0.1 1e-11 44.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EOO03059.1 - 1.6e-15 56.7 0.0 0.0036 17.1 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 EOO03059.1 - 3e-08 33.2 5.7 3e-08 33.2 5.7 3.2 3 0 0 3 3 3 1 Putative RRM domain RRM_7 PF16367.5 EOO03059.1 - 1.2e-06 28.5 0.0 0.0079 16.3 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif DUF4523 PF15023.6 EOO03059.1 - 3.7e-06 26.9 0.0 0.0086 15.9 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_3 PF08777.11 EOO03059.1 - 0.01 15.9 0.1 0.28 11.2 0.1 2.7 3 0 0 3 3 3 0 RNA binding motif RRM_Rrp7 PF17799.1 EOO03059.1 - 0.014 15.2 0.0 0.89 9.3 0.0 3.4 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain Spo7_2_N PF15407.6 EOO03059.1 - 0.039 13.6 0.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 Sporulation protein family 7 Nup35_RRM_2 PF14605.6 EOO03059.1 - 0.04 13.9 0.0 25 5.0 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 EOO03059.1 - 0.054 13.5 0.7 0.2 11.7 0.0 2.3 3 0 0 3 3 3 0 RNA binding domain Voltage_CLC PF00654.20 EOO03060.1 - 2.3e-49 168.5 20.3 2.9e-49 168.2 20.3 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 EOO03060.1 - 2.3e-06 27.9 0.0 0.0025 18.2 0.0 2.8 3 0 0 3 3 3 2 CBS domain LacI PF00356.21 EOO03060.1 - 0.18 11.6 1.6 0.44 10.4 1.6 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family VWA_2 PF13519.6 EOO03061.1 - 0.013 16.1 0.0 0.033 14.9 0.0 1.8 1 0 0 1 1 1 0 von Willebrand factor type A domain Fcf2 PF08698.11 EOO03062.1 - 6.2e-35 119.5 1.0 4.6e-34 116.7 0.1 2.2 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing Ribos_L4_asso_C PF14374.6 EOO03062.1 - 0.029 14.4 0.0 0.08 13.0 0.0 1.8 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain CBFD_NFYB_HMF PF00808.23 EOO03063.1 - 1.1e-19 70.4 0.4 1.6e-19 69.9 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EOO03063.1 - 8.6e-15 55.3 0.1 1.5e-14 54.5 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 EOO03063.1 - 0.047 14.0 0.0 0.074 13.4 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sad1_UNC PF07738.13 EOO03064.1 - 4.5e-32 110.8 0.0 7.1e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 EOO03064.1 - 0.028 14.5 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 F5/8 type C domain Beta-TrCP_D PF12125.8 EOO03064.1 - 0.17 11.8 0.1 0.17 11.8 0.1 1.9 2 0 0 2 2 2 0 D domain of beta-TrCP Noelin-1 PF12308.8 EOO03064.1 - 1.7 8.7 4.3 1 9.4 0.7 2.3 1 1 1 2 2 2 0 Neurogenesis glycoprotein Ribosomal_L12 PF00542.19 EOO03066.1 - 9.2e-20 70.8 3.3 9.2e-20 70.8 3.3 2.3 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EOO03066.1 - 6.2e-12 45.0 10.5 9.4e-12 44.5 8.0 2.6 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 EOO03066.1 - 0.014 15.9 3.5 0.014 15.9 3.5 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Dor1 PF04124.12 EOO03066.1 - 0.061 12.0 0.1 0.1 11.3 0.1 1.3 1 0 0 1 1 1 0 Dor1-like family Nitroreductase PF00881.24 EOO03067.1 - 0.0001 22.4 0.0 0.00013 22.1 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family SRAP PF02586.14 EOO03068.1 - 1.8e-58 197.7 0.0 3e-58 196.9 0.0 1.4 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Cellulase PF00150.18 EOO03069.1 - 3.8e-52 177.5 0.3 4.3e-52 177.3 0.3 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ysc84 PF04366.12 EOO03070.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.6 2 0 0 2 2 2 0 Las17-binding protein actin regulator CdhC PF03598.15 EOO03071.1 - 0.034 14.0 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit Ank_2 PF12796.7 EOO03072.1 - 6.2e-147 478.6 15.8 1.9e-16 60.4 0.1 8.0 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.30 EOO03072.1 - 1.8e-86 281.1 10.5 4.4e-05 23.7 0.0 15.1 15 0 0 15 15 15 15 Ankyrin repeat Ank_3 PF13606.6 EOO03072.1 - 8.8e-82 259.2 0.0 0.0004 20.6 0.0 15.1 15 0 0 15 15 15 15 Ankyrin repeat Ank_4 PF13637.6 EOO03072.1 - 3.7e-81 266.5 0.2 4.5e-10 39.9 0.0 9.5 6 3 5 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 EOO03072.1 - 6.4e-58 192.1 1.6 2.1e-06 27.9 0.0 10.8 4 4 6 11 11 11 10 Ankyrin repeats (many copies) MltA PF03562.17 EOO03072.1 - 1.6e-11 44.5 6.3 28 4.4 0.0 11.4 4 3 9 13 13 13 0 MltA specific insert domain VWA_3_C PF18571.1 EOO03072.1 - 2e-08 34.0 37.4 2.9 7.8 0.1 13.2 15 0 0 15 15 15 4 von Willebrand factor type A C-terminal domain PEGA PF08308.11 EOO03072.1 - 8.9e-08 31.9 1.0 63 3.6 0.0 10.2 13 0 0 13 13 13 0 PEGA domain Nse4-Nse3_bdg PF15412.6 EOO03072.1 - 4.2e-07 30.0 16.5 20 5.4 0.0 11.1 13 0 0 13 13 12 0 Binding domain of Nse4/EID3 to Nse3-MAGE Ribosomal_S6 PF01250.17 EOO03072.1 - 2.6e-06 27.6 0.4 8.1 6.8 0.0 6.5 5 4 2 7 7 7 1 Ribosomal protein S6 BfiI_DBD PF18243.1 EOO03072.1 - 3.7e-06 26.6 0.0 4 7.0 0.0 5.4 2 2 4 7 7 7 1 Metal-independent restriction enzyme BfiI DNA binding domain DUF1874 PF08960.10 EOO03072.1 - 8.6e-06 25.8 6.8 18 5.5 0.0 9.1 5 4 4 11 11 11 0 Domain of unknown function (DUF1874) Cthe_2159 PF14262.6 EOO03072.1 - 1.5e-05 24.5 7.6 0.68 9.2 0.2 5.1 1 1 2 5 5 5 2 Carbohydrate-binding domain-containing protein Cthe_2159 DUF3156 PF11354.8 EOO03072.1 - 1.7e-05 24.8 0.0 8.3 6.3 0.0 6.5 4 4 1 6 6 6 1 Protein of unknown function (DUF3156) DNA_pol3_tau_5 PF12170.8 EOO03072.1 - 0.0013 18.8 0.1 6 6.9 0.0 6.0 3 2 5 9 9 9 1 DNA polymerase III tau subunit V interacting with alpha GATase_7 PF13537.6 EOO03072.1 - 0.0053 16.7 0.1 93 3.0 0.0 6.7 7 4 3 11 11 11 0 Glutamine amidotransferase domain DUF1934 PF09148.10 EOO03072.1 - 0.0056 16.7 0.0 1.7e+02 2.2 0.0 6.3 3 2 3 8 8 8 0 Domain of unknown function (DUF1934) BiPBP_C PF06832.12 EOO03072.1 - 0.14 12.3 0.1 78 3.4 0.0 4.1 3 1 1 4 4 4 0 Penicillin-Binding Protein C-terminus Family Ank_5 PF13857.6 EOO03073.1 - 2.6e-11 43.5 0.3 1.5e-05 25.1 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EOO03073.1 - 4.6e-10 40.0 0.0 8.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) HTH_33 PF13592.6 EOO03073.1 - 4.2e-08 32.7 0.1 8.7e-08 31.7 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix Ank_4 PF13637.6 EOO03073.1 - 8.3e-07 29.4 0.1 5.8e-06 26.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EOO03073.1 - 1.3e-06 28.2 0.0 0.0013 19.0 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat DDE_3 PF13358.6 EOO03073.1 - 1.6e-06 27.9 0.0 3.8e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Ank PF00023.30 EOO03073.1 - 0.00088 19.6 0.0 0.093 13.2 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat HTH_Tnp_Tc3_2 PF01498.18 EOO03073.1 - 0.012 15.8 0.1 0.023 14.9 0.1 1.5 1 0 0 1 1 1 0 Transposase Orbi_VP5 PF00901.17 EOO03073.1 - 0.12 10.7 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 NOA36 PF06524.12 EOO03074.1 - 0.089 12.1 6.8 0.1 11.9 6.8 1.1 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 EOO03074.1 - 0.096 12.6 4.4 0.099 12.5 4.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.11 EOO03074.1 - 0.13 12.2 3.0 0.17 11.9 3.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.12 EOO03074.1 - 0.24 10.8 7.7 0.25 10.7 7.7 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 EOO03074.1 - 0.33 10.0 11.3 0.35 10.0 11.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.12 EOO03074.1 - 0.71 9.2 8.3 0.81 9.0 8.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFB6 PF17110.5 EOO03074.1 - 1.8 8.3 6.6 2.5 7.8 6.6 1.3 1 1 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH FAM176 PF14851.6 EOO03074.1 - 2.2 7.9 5.5 2.9 7.5 5.5 1.3 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 EOO03074.1 - 2.3 6.4 8.6 2.4 6.3 8.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EOO03074.1 - 3.3 5.8 11.1 3.5 5.7 11.1 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 EOO03074.1 - 7.9 4.9 9.5 9.6 4.6 9.5 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pes-10 PF07149.11 EOO03074.1 - 8.8 5.3 8.0 9.9 5.1 8.0 1.0 1 0 0 1 1 1 0 Pes-10 ABC_tran PF00005.27 EOO03076.1 - 3.5e-49 166.8 0.1 5.2e-26 91.8 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EOO03076.1 - 4.1e-23 82.4 13.7 4.1e-23 82.4 13.7 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 EOO03076.1 - 6.9e-09 35.5 1.9 0.22 10.9 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EOO03076.1 - 9.7e-07 28.9 1.3 0.028 14.2 0.0 3.8 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EOO03076.1 - 2.5e-06 27.5 0.8 0.018 15.0 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EOO03076.1 - 4.6e-06 26.3 0.6 0.024 14.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 EOO03076.1 - 1.3e-05 24.8 0.1 0.083 12.4 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 EOO03076.1 - 3.6e-05 23.1 0.0 0.022 13.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 EOO03076.1 - 5.1e-05 23.3 0.1 0.16 12.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 EOO03076.1 - 0.0001 22.2 0.1 0.017 14.9 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 EOO03076.1 - 0.00029 21.3 0.1 0.15 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EOO03076.1 - 0.00043 20.6 2.9 0.77 10.0 0.1 3.3 2 2 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 EOO03076.1 - 0.00051 20.1 0.1 0.073 13.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA PF00004.29 EOO03076.1 - 0.00081 19.8 0.2 0.24 11.8 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EOO03076.1 - 0.0023 18.5 0.7 0.22 12.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EOO03076.1 - 0.0059 17.0 0.0 4.1 7.9 0.0 3.1 3 0 0 3 3 3 1 RNA helicase Viral_helicase1 PF01443.18 EOO03076.1 - 0.0067 16.2 0.0 5.2 6.7 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 EOO03076.1 - 0.015 14.6 0.0 2.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.6 EOO03076.1 - 0.033 14.4 0.7 15 5.9 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit TsaE PF02367.17 EOO03076.1 - 0.043 13.8 0.4 1.6 8.7 0.0 2.9 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AIG1 PF04548.16 EOO03076.1 - 0.071 12.4 0.1 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 AIG1 family AAA_30 PF13604.6 EOO03076.1 - 0.089 12.5 0.0 16 5.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 EOO03076.1 - 0.2 10.7 1.7 7.8 5.5 0.3 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_5 PF07728.14 EOO03076.1 - 0.23 11.4 0.5 13 5.7 0.1 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 EOO03076.1 - 0.32 10.7 2.3 0.7 9.6 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Rad21_Rec8_N PF04825.13 EOO03077.1 - 6e-32 110.1 0.0 1e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EOO03077.1 - 2.5e-08 33.1 0.0 6.3e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ALO PF04030.14 EOO03079.1 - 6.4e-91 304.8 0.1 8.5e-91 304.4 0.1 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EOO03079.1 - 2.3e-28 98.7 0.0 4.5e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.25 EOO03080.1 - 5.6e-35 120.6 0.5 7.3e-35 120.2 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03080.1 - 2.5e-27 95.9 1.8 3.4e-27 95.5 1.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO03080.1 - 0.014 15.3 0.5 0.81 9.6 0.2 2.6 2 1 0 2 2 2 0 KR domain Epimerase PF01370.21 EOO03080.1 - 0.018 14.5 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDI PF00996.18 EOO03081.1 - 1.7e-06 26.9 0.0 1.8e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor ProQ_C PF17516.2 EOO03081.1 - 0.14 11.6 0.2 0.27 10.7 0.2 1.4 1 0 0 1 1 1 0 ProQ C-terminal domain Myosin_N PF02736.19 EOO03081.1 - 0.24 11.3 1.4 0.65 9.9 1.4 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AA_permease_2 PF13520.6 EOO03083.1 - 1.1e-67 228.7 15.8 1.4e-67 228.4 15.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EOO03083.1 - 3e-10 39.3 12.7 3e-10 39.3 12.7 2.2 2 1 0 2 2 2 1 Amino acid permease Ndc1_Nup PF09531.10 EOO03084.1 - 1.5 7.4 5.5 3.2 6.3 5.5 1.6 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_M61 PF05299.12 EOO03084.1 - 1.9 8.9 0.0 1.9 8.9 0.0 2.7 2 1 1 3 3 3 0 M61 glycyl aminopeptidase Bac_luciferase PF00296.20 EOO03085.1 - 1.1e-38 133.4 0.0 1.3e-38 133.2 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_N PF08240.12 EOO03086.1 - 3.5e-05 23.6 0.0 0.0001 22.2 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EOO03086.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EOO03086.1 - 0.058 13.3 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase zf-CCHC PF00098.23 EOO03087.1 - 0.027 14.6 2.6 0.052 13.6 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF3584 PF12128.8 EOO03088.1 - 0.0001 20.0 60.6 0.0001 20.0 60.6 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 EOO03088.1 - 0.00029 20.9 21.7 0.00029 20.9 21.7 7.5 2 2 3 6 6 6 1 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 EOO03088.1 - 0.0087 16.6 22.4 0.0087 16.6 22.4 7.1 1 1 4 6 6 6 2 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 EOO03088.1 - 0.014 15.4 13.1 0.014 15.4 13.1 6.1 1 1 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GIT_CC PF16559.5 EOO03088.1 - 1.6 8.7 0.0 0.24 11.3 1.5 6.2 6 1 1 7 7 7 0 GIT coiled-coil Rho guanine nucleotide exchange factor DinB_2 PF12867.7 EOO03088.1 - 2.9 8.4 8.4 0.76 10.3 0.3 3.8 3 1 0 3 3 3 0 DinB superfamily Spc7 PF08317.11 EOO03088.1 - 4.2 6.2 101.6 1.1 8.1 18.6 4.6 1 1 4 5 5 5 0 Spc7 kinetochore protein PI_PP_I PF18363.1 EOO03088.1 - 4.5 7.5 8.4 15 5.9 0.2 4.0 3 1 0 3 3 3 0 Phosphoinositide phosphatase insertion domain HOOK PF05622.12 EOO03088.1 - 4.7 5.2 100.7 2.3 6.2 44.3 2.7 1 1 1 2 2 2 0 HOOK protein DUF4355 PF14265.6 EOO03090.1 - 0.021 15.0 1.2 0.021 15.0 1.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4355) tRNA-synt_1c PF00749.21 EOO03090.1 - 0.044 12.7 1.3 0.088 11.7 1.3 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain RTA1 PF04479.13 EOO03091.1 - 1.1e-38 132.9 3.0 1.3e-38 132.8 3.0 1.0 1 0 0 1 1 1 1 RTA1 like protein Cation_ATPase_C PF00689.21 EOO03091.1 - 0.024 14.3 0.5 0.035 13.8 0.5 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus SRTM1 PF15872.5 EOO03091.1 - 0.042 14.0 0.4 0.1 12.7 0.1 1.8 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 Transmemb_17 PF09799.9 EOO03091.1 - 0.065 13.8 3.4 0.099 13.2 3.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein CTV_P6 PF06706.11 EOO03091.1 - 0.94 9.2 7.2 0.1 12.3 2.4 1.8 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein GAS PF13851.6 EOO03092.1 - 8.4e-06 25.3 79.2 0.00062 19.2 20.1 5.7 2 1 3 5 5 5 4 Growth-arrest specific micro-tubule binding BST2 PF16716.5 EOO03092.1 - 0.021 15.4 4.8 0.021 15.4 4.8 9.4 2 2 9 12 12 12 0 Bone marrow stromal antigen 2 CorA PF01544.18 EOO03092.1 - 0.03 13.7 0.4 0.03 13.7 0.4 5.2 2 1 4 6 6 6 0 CorA-like Mg2+ transporter protein Trimer_CC PF08954.11 EOO03092.1 - 0.039 13.5 17.5 0.055 13.0 0.8 5.3 6 0 0 6 6 6 0 Trimerisation motif MAD PF05557.13 EOO03092.1 - 0.094 11.1 82.1 0.55 8.5 19.8 4.2 1 1 3 4 4 4 0 Mitotic checkpoint protein Spc7 PF08317.11 EOO03092.1 - 0.72 8.7 83.4 0.33 9.8 21.5 5.6 1 1 3 5 5 5 0 Spc7 kinetochore protein L31 PF09784.9 EOO03092.1 - 1.4 9.3 12.5 0.32 11.5 0.6 4.3 2 1 1 3 3 3 0 Mitochondrial ribosomal protein L31 TMF_TATA_bd PF12325.8 EOO03092.1 - 4.6 7.5 77.4 2.4 8.4 0.3 8.9 2 1 6 8 8 8 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 EOO03092.1 - 7.7 6.6 79.6 0.46 10.6 8.9 7.7 3 1 2 6 6 6 0 Afadin- and alpha -actinin-Binding CRR7 PF12095.8 EOO03092.1 - 9.1 6.8 22.0 0.54 10.7 0.2 5.9 5 3 0 5 5 5 0 Protein CHLORORESPIRATORY REDUCTION 7 Scaffolding_pro PF11418.8 EOO03092.1 - 9.9 6.8 19.0 3.2 8.4 0.3 4.9 4 2 0 4 4 4 0 Phi29 scaffolding protein ANTH PF07651.16 EOO03093.1 - 4.1e-82 275.3 0.0 4.1e-82 275.3 0.0 2.7 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.17 EOO03093.1 - 2.5e-55 186.9 7.0 2.5e-55 186.9 7.0 6.5 4 1 3 7 7 7 2 I/LWEQ domain CENP-B_N PF04218.13 EOO03093.1 - 0.075 12.7 0.3 0.52 10.0 0.0 2.4 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain Surfac_D-trimer PF09006.11 EOO03093.1 - 0.59 10.1 5.9 0.23 11.4 1.5 2.8 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Corona_S2 PF01601.16 EOO03093.1 - 0.79 8.1 4.9 0.42 9.0 0.2 2.3 1 1 1 2 2 2 0 Coronavirus S2 glycoprotein Pterin_bind PF00809.22 EOO03094.1 - 2.5e-75 253.3 0.0 2.1e-74 250.3 0.0 2.0 1 1 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EOO03094.1 - 5.6e-29 100.9 0.0 1e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Glyoxalase_6 PF18029.1 EOO03094.1 - 0.04 14.7 2.5 7.1 7.5 0.0 3.1 3 0 0 3 3 3 0 Glyoxalase-like domain DUF2922 PF11148.8 EOO03094.1 - 0.083 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) TRM PF02005.16 EOO03095.1 - 3e-108 362.3 0.0 6.8e-94 315.1 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EOO03095.1 - 0.015 15.0 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Met-10+ like-protein SLATT_fungal PF18142.1 EOO03096.1 - 3.1e-25 88.5 0.1 3.4e-25 88.4 0.1 1.0 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Claudin_2 PF13903.6 EOO03096.1 - 0.097 12.4 1.3 0.12 12.2 1.3 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DAGK_cat PF00781.24 EOO03097.1 - 5.3e-10 39.0 0.0 2e-09 37.2 0.0 2.0 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain ATG16 PF08614.11 EOO03098.1 - 0.00027 21.2 12.0 0.0097 16.2 14.6 2.0 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) IFT57 PF10498.9 EOO03098.1 - 0.061 12.3 11.3 0.13 11.2 10.6 1.7 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF87 PF01935.17 EOO03098.1 - 0.14 12.3 2.9 0.31 11.1 2.9 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain Laminin_II PF06009.12 EOO03098.1 - 1.1 9.3 4.5 0.23 11.5 0.8 1.7 2 0 0 2 2 2 0 Laminin Domain II NYD-SP28_assoc PF14775.6 EOO03098.1 - 1.5 9.0 7.7 16 5.7 0.0 3.3 3 0 0 3 3 3 0 Sperm tail C-terminal domain VASt PF16016.5 EOO03099.1 - 1.7e-40 138.9 0.1 3e-40 138.1 0.1 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EOO03099.1 - 2.8e-24 85.2 0.0 4.6e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 GRAM domain NAGidase PF07555.13 EOO03099.1 - 0.2 11.0 1.1 0.49 9.7 0.2 1.9 1 1 0 2 2 2 0 beta-N-acetylglucosaminidase Acetyltransf_3 PF13302.7 EOO03100.1 - 6e-14 52.9 0.0 8.7e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EOO03100.1 - 0.001 19.3 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Sugar_tr PF00083.24 EOO03101.1 - 4.5e-34 118.1 4.8 5.2e-34 117.9 4.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO03101.1 - 4.7e-17 61.9 10.6 6.5e-17 61.5 10.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily FAE1_CUT1_RppA PF08392.12 EOO03101.1 - 0.16 11.2 0.0 0.35 10.1 0.0 1.5 2 0 0 2 2 2 0 FAE1/Type III polyketide synthase-like protein THOC2_N PF16134.5 EOO03102.1 - 1e-206 688.4 0.0 2e-206 687.5 0.0 1.5 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EOO03102.1 - 2.2e-99 332.5 3.8 4.4e-99 331.5 3.8 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EOO03102.1 - 3.7e-25 87.8 0.0 1e-24 86.4 0.0 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Vps5 PF09325.10 EOO03103.1 - 4.5e-12 46.0 0.7 6.8e-12 45.4 0.7 1.1 1 0 0 1 1 1 1 Vps5 C terminal like NST1 PF13945.6 EOO03103.1 - 0.04 14.0 2.8 0.065 13.3 2.8 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator NB-ARC PF00931.22 EOO03104.1 - 2.1e-11 43.5 0.0 2.5e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 EOO03104.1 - 1.7e-05 25.1 0.0 3.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EOO03104.1 - 0.0069 16.3 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 EOO03104.1 - 0.033 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EOO03104.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FAR1 PF03101.15 EOO03105.1 - 5.5e-05 23.8 0.0 0.00011 22.8 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain Golgin_A5 PF09787.9 EOO03105.1 - 0.00091 18.8 1.9 0.0013 18.3 1.9 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 CENP-K PF11802.8 EOO03105.1 - 0.018 14.6 1.3 0.018 14.6 1.3 1.6 2 0 0 2 2 2 0 Centromere-associated protein K OmpH PF03938.14 EOO03105.1 - 0.018 15.4 1.7 0.84 10.0 2.3 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Med9 PF07544.13 EOO03105.1 - 0.022 14.8 2.6 0.058 13.5 2.6 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 CdvA PF18822.1 EOO03105.1 - 0.036 13.9 3.9 0.08 12.8 3.9 1.5 1 0 0 1 1 1 0 CdvA-like coiled-coil domain Prefoldin_2 PF01920.20 EOO03105.1 - 0.078 12.9 4.5 0.14 12.1 4.5 1.4 1 0 0 1 1 1 0 Prefoldin subunit DUF262 PF03235.14 EOO03105.1 - 0.16 12.1 0.7 0.22 11.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Prefoldin PF02996.17 EOO03105.1 - 0.19 11.6 4.3 0.4 10.6 4.3 1.5 1 0 0 1 1 1 0 Prefoldin subunit COG2 PF06148.11 EOO03105.1 - 0.24 11.5 2.9 1 9.5 2.6 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 EOO03105.1 - 1.3 7.9 7.1 1.8 7.3 6.3 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein AAA_6 PF12774.7 EOO03106.1 - 1.4e-126 421.9 0.0 7.4e-126 419.5 0.0 2.4 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 EOO03106.1 - 5.2e-125 418.2 4.3 5.2e-125 418.2 4.3 4.8 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EOO03106.1 - 3.1e-118 395.4 6.0 3.1e-118 395.4 6.0 5.7 4 2 1 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EOO03106.1 - 3.5e-73 245.4 0.8 3.5e-73 245.4 0.8 3.7 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 EOO03106.1 - 7.6e-67 225.4 0.0 6.2e-66 222.4 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EOO03106.1 - 5e-42 143.5 0.0 1.7e-36 125.4 0.0 4.7 5 0 0 5 5 4 2 P-loop containing dynein motor region MT PF12777.7 EOO03106.1 - 3.8e-41 141.3 9.7 3.8e-41 141.3 9.7 2.3 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EOO03106.1 - 5.2e-32 110.7 0.0 2.4e-11 43.8 0.0 6.3 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 EOO03106.1 - 1.8e-30 105.5 0.0 2e-27 95.6 0.0 4.1 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 EOO03106.1 - 7.4e-29 100.7 0.0 1.8e-28 99.4 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EOO03106.1 - 7.7e-16 58.6 1.4 0.0096 16.2 0.0 6.8 5 1 1 6 6 6 3 AAA domain AAA PF00004.29 EOO03106.1 - 5.5e-14 52.7 0.0 0.00058 20.3 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) Dynein_AAA_lid PF17852.1 EOO03106.1 - 4.4e-13 49.4 0.0 1.5e-12 47.7 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 EOO03106.1 - 7.9e-13 49.1 0.3 1.8 8.9 0.0 8.1 6 0 0 6 6 6 2 AAA ATPase domain AAA_33 PF13671.6 EOO03106.1 - 2e-09 37.8 0.8 0.46 10.6 0.1 5.0 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.6 EOO03106.1 - 2.3e-09 37.9 0.3 0.065 13.8 0.0 5.6 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.6 EOO03106.1 - 8.9e-06 25.4 0.0 0.64 9.8 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SSE PF00437.20 EOO03106.1 - 1.1e-05 24.6 0.0 0.019 14.0 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_14 PF13173.6 EOO03106.1 - 3.1e-05 24.0 0.0 1.1 9.3 0.0 4.1 3 0 0 3 3 3 2 AAA domain AAA_lid_1 PF17857.1 EOO03106.1 - 4.4e-05 23.6 0.5 0.00068 19.8 0.0 3.2 3 0 0 3 3 2 1 AAA+ lid domain ABC_tran PF00005.27 EOO03106.1 - 5.5e-05 23.7 0.1 3.7 8.1 0.0 4.9 4 0 0 4 4 3 1 ABC transporter AAA_25 PF13481.6 EOO03106.1 - 0.0001 22.0 0.1 0.24 10.9 0.0 4.3 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 EOO03106.1 - 0.00014 21.3 0.9 0.67 9.3 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EOO03106.1 - 0.00067 19.4 0.2 11 5.7 0.0 5.1 5 0 0 5 5 4 0 AAA domain AAA_19 PF13245.6 EOO03106.1 - 0.00088 19.6 1.5 0.28 11.5 0.0 4.4 5 0 0 5 5 3 1 AAA domain AAA_30 PF13604.6 EOO03106.1 - 0.0022 17.7 1.7 39 3.9 0.0 4.9 4 1 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.18 EOO03106.1 - 0.0027 17.1 2.0 2.4 7.5 0.0 4.3 4 0 0 4 4 4 1 FtsK/SpoIIIE family IstB_IS21 PF01695.17 EOO03106.1 - 0.0045 16.7 0.4 0.72 9.6 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EOO03106.1 - 0.011 16.1 0.1 44 4.5 0.0 4.9 4 0 0 4 4 4 0 RNA helicase Zeta_toxin PF06414.12 EOO03106.1 - 0.014 14.7 0.1 7.9 5.7 0.0 4.0 4 0 0 4 4 4 0 Zeta toxin Rad17 PF03215.15 EOO03106.1 - 0.046 13.7 0.4 6.7 6.6 0.0 3.8 5 0 0 5 5 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 EOO03106.1 - 0.057 13.3 0.3 39 4.1 0.0 4.4 4 0 0 4 4 3 0 NTPase Vps23_core PF09454.10 EOO03106.1 - 0.1 12.5 1.9 15 5.7 0.1 3.1 2 0 0 2 2 2 0 Vps23 core domain DUF4482 PF14818.6 EOO03106.1 - 0.12 13.3 8.7 43 5.0 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) NACHT PF05729.12 EOO03106.1 - 0.36 10.7 5.1 31 4.4 0.0 4.7 4 0 0 4 4 3 0 NACHT domain ALMT PF11744.8 EOO03106.1 - 0.67 8.7 5.0 2 7.1 5.0 1.8 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4611 PF15387.6 EOO03106.1 - 1.4 9.2 7.1 0.5 10.6 0.0 3.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4611) PduV-EutP PF10662.9 EOO03106.1 - 2.3 7.9 4.1 11 5.7 0.1 4.2 5 0 0 5 5 5 0 Ethanolamine utilisation - propanediol utilisation MbeB_N PF04837.12 EOO03106.1 - 3 8.2 6.1 2.6 8.4 0.1 3.4 3 0 0 3 3 2 0 MbeB-like, N-term conserved region Xpo1 PF08389.12 EOO03107.1 - 4.6e-28 98.2 5.0 9.4e-28 97.1 1.2 3.3 3 0 0 3 3 3 1 Exportin 1-like protein Adaptin_N PF01602.20 EOO03107.1 - 0.00056 18.6 1.0 0.014 14.0 0.4 2.3 2 0 0 2 2 2 1 Adaptin N terminal region IBN_N PF03810.19 EOO03107.1 - 0.0018 18.2 0.0 0.0066 16.3 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain UME PF08064.13 EOO03107.1 - 0.02 14.8 0.7 1 9.3 0.0 3.5 3 0 0 3 3 3 0 UME (NUC010) domain Ribosomal_S5_C PF03719.15 EOO03107.1 - 0.14 11.7 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain ABATE PF07336.11 EOO03107.1 - 0.26 12.0 2.4 5.6 7.6 0.8 3.2 2 1 0 2 2 2 0 Putative stress-induced transcription regulator Phasin_2 PF09361.10 EOO03107.1 - 0.71 10.2 3.3 7.8 6.8 0.3 3.7 4 0 0 4 4 4 0 Phasin protein DUF2269 PF10027.9 EOO03108.1 - 0.0082 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) Baculo_PEP_C PF04513.12 EOO03108.1 - 0.06 13.4 0.5 0.12 12.4 0.5 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin_2 PF09361.10 EOO03108.1 - 0.35 11.2 3.3 3.6 7.9 0.0 2.7 2 1 1 3 3 3 0 Phasin protein Peptidase_S28 PF05577.12 EOO03109.1 - 3.9e-48 164.3 0.1 5.5e-48 163.8 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DUF2920 PF11144.8 EOO03109.1 - 0.00048 19.4 0.1 0.00074 18.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Peptidase_S37 PF05576.11 EOO03109.1 - 0.044 12.5 0.5 0.13 10.9 0.6 1.6 1 1 0 1 1 1 0 PS-10 peptidase S37 SHE3 PF17078.5 EOO03111.1 - 0.0026 17.5 4.1 0.13 11.9 0.2 2.3 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 CENP-Q PF13094.6 EOO03111.1 - 0.0039 17.4 3.9 0.0039 17.4 3.9 3.3 2 2 1 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Sec34 PF04136.15 EOO03111.1 - 0.0052 16.7 0.3 0.31 10.9 0.0 2.4 2 0 0 2 2 2 1 Sec34-like family Cnn_1N PF07989.11 EOO03111.1 - 0.01 16.0 2.5 2.4 8.4 0.1 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 CtIP_N PF10482.9 EOO03111.1 - 0.056 13.5 1.5 2.8 8.0 0.1 2.4 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Cep57_MT_bd PF06657.13 EOO03111.1 - 0.071 13.6 7.4 0.73 10.3 0.7 2.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FAM92 PF06730.11 EOO03111.1 - 0.096 12.1 2.6 0.11 11.9 0.4 2.0 2 0 0 2 2 2 0 FAM92 protein NRBF2_MIT PF17169.4 EOO03111.1 - 0.11 12.8 3.9 0.68 10.2 1.9 2.7 2 0 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 APC_N_CC PF16689.5 EOO03111.1 - 0.19 11.9 4.9 0.5 10.5 1.3 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain bZIP_1 PF00170.21 EOO03111.1 - 0.28 11.3 10.6 1.7 8.8 2.5 2.8 2 0 0 2 2 2 0 bZIP transcription factor MPS2 PF17060.5 EOO03111.1 - 0.32 10.2 4.0 1.3 8.2 3.9 1.9 1 1 0 1 1 1 0 Monopolar spindle protein 2 KxDL PF10241.9 EOO03111.1 - 0.36 11.1 5.1 3 8.2 0.5 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein Prefoldin_2 PF01920.20 EOO03111.1 - 0.44 10.5 10.0 0.15 12.0 2.5 2.5 2 0 0 2 2 2 0 Prefoldin subunit DUF1043 PF06295.12 EOO03111.1 - 0.44 10.5 3.0 0.89 9.6 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF812 PF05667.11 EOO03111.1 - 0.67 8.8 7.0 0.053 12.4 2.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) FlaC_arch PF05377.11 EOO03111.1 - 0.67 10.4 3.7 1.2 9.5 0.4 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ax_dynein_light PF10211.9 EOO03111.1 - 1.2 9.0 9.7 4.7 7.1 1.9 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain FapA PF03961.13 EOO03111.1 - 1.2 7.6 8.0 0.25 9.9 2.6 2.0 1 1 0 2 2 2 0 Flagellar Assembly Protein A GAS PF13851.6 EOO03111.1 - 1.3 8.4 10.8 0.58 9.5 3.0 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.7 EOO03111.1 - 1.5 9.0 11.5 22 5.2 11.4 2.5 1 1 0 1 1 1 0 Tropomyosin like DUF4201 PF13870.6 EOO03111.1 - 1.8 8.3 11.0 19 4.9 4.8 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Jnk-SapK_ap_N PF09744.9 EOO03111.1 - 2 8.6 8.9 15 5.8 0.4 2.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Syntaxin-6_N PF09177.11 EOO03111.1 - 3 8.4 5.6 12 6.5 0.7 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal GrpE PF01025.19 EOO03111.1 - 3.2 7.4 10.4 1.5 8.5 3.9 2.3 2 0 0 2 2 2 0 GrpE CCDC-167 PF15188.6 EOO03111.1 - 5.1 7.5 6.4 29 5.1 6.4 2.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 BLOC1_2 PF10046.9 EOO03111.1 - 5.6 7.3 7.2 2.5 8.5 0.6 2.6 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.8 EOO03111.1 - 6.2 6.9 18.6 1.1 9.4 3.7 2.9 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding DivIVA PF05103.13 EOO03111.1 - 7.6 6.6 15.1 0.11 12.6 2.2 2.7 3 0 0 3 3 2 0 DivIVA protein Phage_GP20 PF06810.11 EOO03111.1 - 7.9 6.3 9.9 5.8 6.7 4.5 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF4363 PF14276.6 EOO03111.1 - 8.8 6.5 9.9 3.9 7.6 2.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) DUF4164 PF13747.6 EOO03111.1 - 9 6.7 11.8 3.9 7.8 1.9 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) BST2 PF16716.5 EOO03111.1 - 9.8 6.8 9.6 3.3 8.4 0.7 3.0 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 ArfGap PF01412.18 EOO03112.1 - 3.1e-35 120.8 0.3 6.2e-35 119.8 0.3 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-H2C2_2 PF13465.6 EOO03113.1 - 6.8e-10 38.9 16.2 2.2e-05 24.7 3.5 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 EOO03113.1 - 2.8e-08 33.7 14.0 0.00048 20.4 4.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EOO03113.1 - 0.00016 22.3 11.5 0.055 14.3 3.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EOO03113.1 - 0.02 15.2 3.0 0.057 13.7 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EOO03113.1 - 0.075 13.7 2.0 0.18 12.5 0.2 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain Dynamin_N PF00350.23 EOO03114.1 - 1.4e-09 38.2 0.0 2.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 EOO03114.1 - 0.0011 19.5 0.0 0.0022 18.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 EOO03114.1 - 0.0025 17.9 0.0 0.0061 16.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EOO03114.1 - 0.0078 15.5 0.0 0.036 13.3 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 EOO03114.1 - 0.0081 16.4 0.2 0.15 12.3 0.1 2.8 2 1 1 3 3 3 1 AAA domain IIGP PF05049.13 EOO03114.1 - 0.012 14.7 0.0 0.095 11.7 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 EOO03114.1 - 0.013 15.8 0.0 0.074 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 EOO03114.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AIG1 PF04548.16 EOO03114.1 - 0.029 13.7 0.1 0.053 12.8 0.1 1.4 1 0 0 1 1 1 0 AIG1 family DUF2312 PF10073.9 EOO03114.1 - 0.17 11.6 1.1 0.6 9.8 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) Abhydrolase_1 PF00561.20 EOO03115.1 - 3.3e-37 128.5 0.0 7.9e-37 127.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EOO03115.1 - 0.00035 21.2 0.2 0.0015 19.2 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 EOO03115.1 - 0.0095 14.8 0.0 0.034 13.0 0.0 1.7 2 0 0 2 2 2 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EOO03115.1 - 0.031 13.5 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Solute_trans_a PF03619.16 EOO03117.1 - 1.8e-71 240.8 14.3 2.2e-71 240.5 14.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha ABA_GPCR PF12430.8 EOO03117.1 - 0.089 12.5 0.6 0.17 11.6 0.6 1.4 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor Senescence PF06911.12 EOO03119.1 - 3e-59 200.4 5.7 4.9e-59 199.7 5.7 1.3 1 0 0 1 1 1 1 Senescence-associated protein OPT PF03169.15 EOO03120.1 - 5.5e-158 527.4 35.3 6.4e-158 527.2 35.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF5325 PF17259.2 EOO03120.1 - 6.9 6.6 6.4 22 5.0 0.0 3.1 1 1 1 2 2 2 0 Family of unknown function (DUF5325) AA_permease PF00324.21 EOO03121.1 - 7e-85 285.4 33.4 1.8e-57 195.0 15.1 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 EOO03121.1 - 2.7e-11 42.9 34.4 3.1e-07 29.6 34.4 2.1 1 1 0 1 1 1 1 Amino acid permease DUF4389 PF14333.6 EOO03121.1 - 0.3 11.1 4.6 1 9.4 1.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) Orthoreo_P10 PF07204.11 EOO03121.1 - 3.8 7.5 9.6 0.16 12.0 2.5 2.3 2 1 1 3 3 3 0 Orthoreovirus membrane fusion protein p10 ADH_N PF08240.12 EOO03122.1 - 9.3e-26 89.8 0.5 2.3e-25 88.6 0.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EOO03122.1 - 4.8e-15 55.7 0.4 3.7e-14 52.8 0.4 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EOO03122.1 - 5.4e-09 35.9 0.2 0.00015 21.3 0.1 2.7 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EOO03122.1 - 0.0022 17.3 1.1 0.0022 17.3 0.1 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EOO03122.1 - 0.0055 16.3 0.9 0.0081 15.7 0.2 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 EOO03122.1 - 0.009 17.1 0.0 0.025 15.6 0.0 1.7 2 0 0 2 2 1 1 Zinc-binding dehydrogenase NAD_binding_8 PF13450.6 EOO03122.1 - 0.017 15.3 0.6 0.054 13.7 0.2 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EOO03122.1 - 0.024 14.2 0.4 0.037 13.6 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.21 EOO03122.1 - 0.05 13.0 0.1 0.081 12.3 0.1 1.2 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.18 EOO03122.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 EOO03122.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EOO03122.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.19 EOO03123.1 - 1.1e-60 205.6 0.0 4.2e-59 200.3 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EOO03123.1 - 1.1e-28 100.6 0.0 2.9e-28 99.2 0.0 1.8 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EOO03123.1 - 2.8e-05 24.3 0.0 7.6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EOO03123.1 - 9.9e-05 21.7 0.0 0.016 14.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EOO03123.1 - 0.00014 21.2 0.0 0.00024 20.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EOO03123.1 - 0.00015 20.9 0.1 0.00024 20.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EOO03123.1 - 0.0022 17.3 0.0 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EOO03123.1 - 0.0033 16.6 0.0 0.0052 15.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EOO03123.1 - 0.0038 16.0 0.0 0.01 14.6 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EOO03123.1 - 0.0066 16.1 0.1 0.018 14.6 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EOO03123.1 - 0.089 12.0 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain PI-PLC-X PF00388.19 EOO03124.1 - 0.00012 21.7 0.0 0.00086 18.9 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain RSN1_7TM PF02714.15 EOO03125.1 - 4.5e-84 282.0 24.1 4.5e-84 282.0 24.1 2.2 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EOO03125.1 - 5.5e-48 162.7 0.8 5.5e-48 162.7 0.8 3.1 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EOO03125.1 - 1.1e-37 129.9 0.0 2e-37 129.1 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EOO03125.1 - 2.7e-31 107.6 0.4 6.8e-31 106.3 0.1 1.8 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter GCP_N_terminal PF17681.1 EOO03126.1 - 1.8e-27 96.8 0.4 4.1e-27 95.6 0.1 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EOO03126.1 - 1.7e-19 70.5 0.0 6.3e-19 68.6 0.0 1.9 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal KSHV_K8 PF07188.11 EOO03126.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein TIM21 PF08294.11 EOO03127.1 - 1.9e-40 138.1 0.0 2.2e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 EOO03127.1 - 2.2e-06 27.4 0.0 5.4e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 B12D PF06522.11 EOO03127.1 - 0.33 10.8 1.6 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit NMO PF03060.15 EOO03128.1 - 1.7e-57 195.3 1.0 2.5e-57 194.8 1.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EOO03128.1 - 1.3e-11 44.1 1.6 2.6e-11 43.1 1.6 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EOO03128.1 - 5.6e-07 28.9 2.2 9.6e-07 28.1 2.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EOO03128.1 - 0.0059 15.8 0.9 0.013 14.7 0.9 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 EOO03128.1 - 0.013 14.7 0.9 0.016 14.4 0.2 1.5 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase NanE PF04131.14 EOO03128.1 - 0.043 13.0 1.6 0.049 12.8 0.1 1.8 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Sld5 PF05916.11 EOO03129.1 - 0.058 13.9 0.1 0.071 13.6 0.1 1.2 1 0 0 1 1 1 0 GINS complex protein DUF1251 PF06856.11 EOO03130.1 - 0.1 12.3 0.3 6.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1251) ABC_tran PF00005.27 EOO03131.1 - 1.5e-46 158.3 0.2 6.9e-22 78.4 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EOO03131.1 - 3e-10 40.4 11.7 2.4e-06 27.6 2.6 4.2 2 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EOO03131.1 - 6.2e-09 35.6 2.1 0.015 14.8 0.1 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EOO03131.1 - 1.4e-07 31.1 0.4 0.0014 18.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EOO03131.1 - 2.9e-07 30.5 0.1 0.027 14.5 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 EOO03131.1 - 2.6e-06 27.8 0.9 0.0025 18.1 0.1 3.0 2 1 0 2 2 2 1 AAA domain ABC_tran_Xtn PF12848.7 EOO03131.1 - 3.3e-06 27.0 1.9 1e-05 25.5 1.9 1.8 1 0 0 1 1 1 1 ABC transporter AAA_27 PF13514.6 EOO03131.1 - 1.2e-05 25.0 0.5 0.0092 15.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EOO03131.1 - 3.8e-05 23.7 4.0 0.17 11.7 0.0 3.4 3 0 0 3 3 3 2 RsgA GTPase AAA_18 PF13238.6 EOO03131.1 - 8.4e-05 23.1 0.2 0.83 10.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 EOO03131.1 - 9.8e-05 22.5 10.6 0.027 14.6 0.4 3.8 4 0 0 4 4 4 2 Helicase HerA, central domain AAA_16 PF13191.6 EOO03131.1 - 0.00016 22.1 5.7 0.11 12.8 2.1 3.0 2 2 0 2 2 2 2 AAA ATPase domain MeaB PF03308.16 EOO03131.1 - 0.0002 20.4 2.2 0.17 10.9 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 EOO03131.1 - 0.00022 21.2 0.8 0.12 12.3 0.0 3.0 2 1 0 2 2 2 1 NACHT domain Dynamin_N PF00350.23 EOO03131.1 - 0.00055 20.0 0.2 1.4 8.9 0.0 2.9 2 1 0 2 2 2 2 Dynamin family AAA_33 PF13671.6 EOO03131.1 - 0.00077 19.6 3.0 0.74 10.0 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 EOO03131.1 - 0.0019 18.7 0.4 0.45 10.9 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EOO03131.1 - 0.0024 18.4 20.5 0.75 10.3 9.9 4.1 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 EOO03131.1 - 0.0024 18.1 7.0 0.3 11.3 0.2 4.1 3 2 0 4 4 4 2 AAA domain DUF815 PF05673.13 EOO03131.1 - 0.0028 16.9 0.2 1.2 8.3 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 EOO03131.1 - 0.0044 16.7 5.1 0.28 10.9 0.0 3.6 4 1 0 4 4 4 1 AAA domain AAA_14 PF13173.6 EOO03131.1 - 0.0049 16.9 0.5 4.8 7.2 0.0 3.6 4 0 0 4 4 4 0 AAA domain NTPase_1 PF03266.15 EOO03131.1 - 0.0058 16.6 0.3 4.2 7.3 0.0 3.2 3 0 0 3 3 3 1 NTPase Arf PF00025.21 EOO03131.1 - 0.0078 15.7 0.7 0.12 11.8 0.2 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_24 PF13479.6 EOO03131.1 - 0.008 15.9 0.7 2.1 8.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EOO03131.1 - 0.008 16.6 0.1 2 8.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.12 EOO03131.1 - 0.01 15.1 0.2 4 6.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 EOO03131.1 - 0.011 15.3 0.2 0.44 10.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 EOO03131.1 - 0.012 15.6 1.5 0.5 10.4 0.0 3.5 5 0 0 5 5 3 0 AAA domain (dynein-related subfamily) Roc PF08477.13 EOO03131.1 - 0.015 15.5 0.1 6 7.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP-synt_ab PF00006.25 EOO03131.1 - 0.021 14.5 0.1 6.3 6.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Thymidylate_kin PF02223.17 EOO03131.1 - 0.042 13.5 2.5 0.69 9.6 0.0 2.8 3 0 0 3 3 2 0 Thymidylate kinase TsaE PF02367.17 EOO03131.1 - 0.061 13.3 0.7 5.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 EOO03131.1 - 0.08 12.8 0.5 16 5.4 0.3 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.6 EOO03131.1 - 0.12 12.1 0.0 0.12 12.1 0.0 3.4 3 1 1 4 4 4 0 AAA ATPase domain cobW PF02492.19 EOO03131.1 - 0.2 11.3 1.3 22 4.6 0.6 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EOO03131.1 - 2.3 7.4 9.6 1.6 7.8 0.1 3.5 5 1 0 5 5 3 0 NB-ARC domain AAA_25 PF13481.6 EOO03131.1 - 5.9 6.4 6.0 2.1 7.9 0.0 3.1 4 0 0 4 4 3 0 AAA domain GTP_EFTU PF00009.27 EOO03132.1 - 9e-42 142.8 0.0 1.5e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EOO03132.1 - 1e-22 80.0 0.1 2.6e-22 78.7 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 EOO03132.1 - 7.4e-15 54.8 0.0 1.1e-06 28.6 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EOO03132.1 - 3.8e-05 24.0 0.0 0.00013 22.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EOO03132.1 - 0.0011 18.8 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 EOO03132.1 - 0.0069 16.2 0.0 0.18 11.6 0.0 2.7 1 1 0 1 1 1 1 Elongation factor G, domain IV cobW PF02492.19 EOO03132.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Myb_Cef PF11831.8 EOO03133.1 - 5.2e-49 167.0 7.0 5.2e-49 167.0 7.0 3.1 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EOO03133.1 - 4e-23 81.3 5.3 8.6e-11 41.9 0.9 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EOO03133.1 - 3.4e-21 75.2 7.7 7.8e-15 54.9 2.8 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EOO03133.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.3 4 0 0 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain JAB PF01398.21 EOO03134.1 - 1.1e-10 41.5 0.0 3.1e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EOO03134.1 - 1.9e-10 41.2 0.0 1e-09 38.8 0.0 2.1 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function SMC_Nse1 PF07574.13 EOO03135.1 - 2.7e-71 239.5 0.0 3.7e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 EOO03135.1 - 2.5e-16 59.7 10.6 3.7e-16 59.1 10.6 1.3 1 0 0 1 1 1 1 RING-like domain PolC_DP2 PF03833.13 EOO03135.1 - 0.46 8.3 4.6 4 5.2 3.5 1.9 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 zf-HC5HC2H PF13771.6 EOO03135.1 - 1 9.7 6.6 2.5 8.4 6.7 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 EOO03135.1 - 1.3 9.4 8.0 2.2 8.7 8.0 1.3 1 0 0 1 1 1 0 Ring finger domain DZR PF12773.7 EOO03135.1 - 5.5 7.1 7.4 32 4.7 7.3 2.0 1 1 0 1 1 1 0 Double zinc ribbon 5-FTHF_cyc-lig PF01812.20 EOO03136.1 - 2.1e-28 99.5 0.0 3e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Dynamin_N PF00350.23 EOO03137.1 - 7.3e-27 94.5 2.3 2.6e-26 92.7 2.3 1.9 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EOO03137.1 - 4.9e-26 91.6 0.0 5.1e-22 78.4 0.1 2.5 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EOO03137.1 - 5.3e-07 29.7 0.1 4.1e-05 23.6 0.1 3.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 EOO03137.1 - 0.00023 21.3 1.3 0.0023 18.1 0.1 2.6 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_16 PF13191.6 EOO03137.1 - 0.017 15.5 0.0 0.21 12.0 0.0 2.7 2 1 1 3 3 3 0 AAA ATPase domain AAA_15 PF13175.6 EOO03137.1 - 0.056 13.2 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AIG1 PF04548.16 EOO03137.1 - 0.064 12.6 0.0 2.4 7.5 0.2 2.5 2 0 0 2 2 2 0 AIG1 family FeoB_N PF02421.18 EOO03137.1 - 0.09 12.3 0.0 9.5 5.7 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 EOO03137.1 - 0.12 12.6 0.0 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF1774 PF08611.10 EOO03138.1 - 7.6e-38 128.7 4.0 7.6e-38 128.7 4.0 2.3 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) Adeno_E3 PF06040.11 EOO03138.1 - 0.028 14.6 0.1 0.085 13.0 0.0 1.7 1 1 0 1 1 1 0 Adenovirus E3 protein SPRY PF00622.28 EOO03139.1 - 0.0001 22.4 0.0 0.0085 16.2 0.0 2.5 2 0 0 2 2 2 2 SPRY domain Acetyltransf_1 PF00583.25 EOO03140.1 - 1.7e-07 31.5 0.0 2.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EOO03140.1 - 0.00067 20.0 0.0 0.0014 19.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EOO03140.1 - 0.0075 16.2 0.2 0.046 13.7 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Nop53 PF07767.11 EOO03142.1 - 0.029 13.8 0.4 0.04 13.3 0.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SUR7 PF06687.12 EOO03143.1 - 2.5e-09 37.1 11.7 2.5e-09 37.1 11.7 1.7 1 1 1 2 2 2 2 SUR7/PalI family DUF2663 PF10864.8 EOO03143.1 - 0.017 15.5 1.1 0.36 11.2 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) Trp_oprn_chp PF09534.10 EOO03143.1 - 0.022 14.5 0.4 0.027 14.3 0.4 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3481 PF11980.8 EOO03143.1 - 0.12 12.1 1.2 2.1 8.1 0.1 2.3 1 1 1 2 2 2 0 C-terminal domain of neuropilin glycoprotein TMIE PF16038.5 EOO03143.1 - 0.13 12.1 0.9 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 TMIE protein TcdA_TcdB_pore PF12920.7 EOO03143.1 - 0.18 10.0 1.2 0.21 9.8 1.2 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain DHHC PF01529.20 EOO03143.1 - 0.3 11.2 6.9 0.18 11.9 2.4 2.0 1 1 1 2 2 2 0 DHHC palmitoyltransferase Claudin_2 PF13903.6 EOO03143.1 - 0.57 9.9 10.8 0.23 11.2 4.6 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction MFS_MOT1 PF16983.5 EOO03144.1 - 1.9e-63 211.8 34.4 2.9e-34 117.8 9.0 2.7 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Xan_ur_permease PF00860.20 EOO03144.1 - 1.7e-05 23.7 30.9 0.014 14.1 27.9 2.2 1 1 1 2 2 2 2 Permease family DUF3328 PF11807.8 EOO03145.1 - 3.5e-45 154.5 0.8 4.2e-45 154.2 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NIF PF03031.18 EOO03147.1 - 3.9e-28 98.2 0.0 9.7e-28 96.9 0.0 1.7 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 EOO03147.1 - 6.5e-07 29.6 0.1 5.5e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EOO03147.1 - 6.7e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 EOO03147.1 - 0.0023 17.8 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 EOO03147.1 - 0.0041 17.5 0.0 0.0093 16.4 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Biotin_lipoyl PF00364.22 EOO03147.1 - 0.021 14.6 0.0 13 5.7 0.1 2.9 2 1 0 2 2 2 0 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EOO03147.1 - 0.042 13.7 0.0 0.78 9.6 0.0 2.7 2 0 0 2 2 2 0 Biotin-lipoyl like BRCT_3 PF18428.1 EOO03147.1 - 0.16 12.1 0.2 0.51 10.4 0.2 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain NmrA PF05368.13 EOO03148.1 - 2.8e-19 69.6 0.1 3.4e-19 69.3 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO03148.1 - 1.4e-15 57.7 0.1 2.2e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EOO03148.1 - 0.0052 17.2 0.3 0.018 15.5 0.1 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EOO03148.1 - 0.015 15.4 0.1 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 EOO03148.1 - 0.023 14.8 0.4 0.18 11.9 0.2 2.1 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 EOO03148.1 - 0.026 14.4 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 EOO03148.1 - 0.081 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RNase_H_2 PF13482.6 EOO03148.1 - 0.12 12.4 0.4 0.22 11.5 0.4 1.5 1 1 0 1 1 1 0 RNase_H superfamily F420_oxidored PF03807.17 EOO03148.1 - 0.15 12.7 0.6 0.44 11.2 0.2 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DIOX_N PF14226.6 EOO03149.1 - 1.2e-23 84.1 0.0 2.2e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EOO03149.1 - 2.5e-19 69.6 0.0 6.4e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_3 PF01494.19 EOO03150.1 - 8.7e-55 186.4 0.0 1.7e-54 185.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EOO03150.1 - 9.3e-09 35.3 1.1 9.4e-05 22.1 0.2 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EOO03150.1 - 1.4e-05 24.0 0.0 0.00016 20.5 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EOO03150.1 - 7.6e-05 22.1 0.1 0.00012 21.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EOO03150.1 - 9e-05 22.6 0.2 0.00046 20.4 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EOO03150.1 - 0.00028 21.4 0.0 0.011 16.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EOO03150.1 - 0.00076 18.8 0.0 0.019 14.2 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EOO03150.1 - 0.0029 16.7 0.2 0.012 14.7 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.16 EOO03150.1 - 0.0041 16.8 0.0 0.0074 15.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 EOO03150.1 - 0.016 14.2 0.1 0.031 13.3 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EOO03150.1 - 0.051 12.8 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.6 EOO03150.1 - 0.098 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 EOO03150.1 - 0.19 12.0 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Asp PF00026.23 EOO03151.1 - 1.8e-51 175.4 4.8 2.4e-51 175.0 4.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EOO03151.1 - 1.4e-08 35.2 0.3 3e-08 34.1 0.3 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EOO03151.1 - 2.2e-05 25.0 2.3 1.5 9.5 0.1 4.4 3 1 0 4 4 4 2 Aspartyl protease gag-asp_proteas PF13975.6 EOO03151.1 - 0.00015 22.2 0.2 5.6 7.6 0.0 4.1 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease Sugar_tr PF00083.24 EOO03152.1 - 7.3e-69 232.8 28.4 2.6e-45 155.1 3.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO03152.1 - 2.8e-09 36.4 20.4 2.8e-09 36.4 20.4 3.2 1 1 2 3 3 3 2 Major Facilitator Superfamily Ndc1_Nup PF09531.10 EOO03152.1 - 4.7 5.8 6.0 7.7 5.1 6.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pectate_lyase PF03211.13 EOO03153.1 - 1.2e-47 162.1 6.9 1.4e-47 161.9 6.9 1.0 1 0 0 1 1 1 1 Pectate lyase Cnd1_N PF12922.7 EOO03155.1 - 8.9e-62 207.8 0.1 8.9e-62 207.8 0.1 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 EOO03155.1 - 1.8e-49 167.9 5.8 2.2e-45 154.6 0.1 3.3 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EOO03155.1 - 2.8e-11 42.7 2.8 0.036 14.3 0.0 6.4 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EOO03155.1 - 9.5e-10 38.7 0.8 0.00047 20.5 0.1 4.5 3 1 0 3 3 3 2 HEAT repeats RTP1_C1 PF10363.9 EOO03155.1 - 7e-06 26.2 0.1 0.16 12.1 0.0 3.5 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EOO03155.1 - 1.3e-05 25.6 4.3 0.045 14.3 0.2 4.9 4 0 0 4 4 4 1 HEAT-like repeat Adaptin_N PF01602.20 EOO03155.1 - 1.5e-05 23.7 4.5 0.0043 15.7 0.4 3.5 3 0 0 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.7 EOO03155.1 - 0.0013 18.0 0.6 0.0013 18.0 0.6 3.7 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.7 EOO03155.1 - 0.063 13.6 0.9 5.6 7.4 0.0 4.2 6 0 0 6 6 6 0 HEAT repeat associated with sister chromatid cohesion BRF1 PF07741.13 EOO03155.1 - 4.9 7.5 10.6 1.1 9.7 1.0 3.6 3 0 0 3 3 3 0 Brf1-like TBP-binding domain UCR_14kD PF02271.16 EOO03156.1 - 0.0019 18.1 3.1 1.9 8.5 0.2 3.1 1 1 2 3 3 3 2 Ubiquinol-cytochrome C reductase complex 14kD subunit Gastrin PF00918.17 EOO03156.1 - 0.065 14.2 0.7 0.17 12.9 0.7 1.8 1 1 0 1 1 1 0 Gastrin/cholecystokinin family DUF4794 PF16042.5 EOO03156.1 - 0.11 13.4 6.9 34 5.5 6.9 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4794) Vpu PF00558.19 EOO03156.1 - 8.8 6.2 5.2 39 4.1 1.2 3.3 1 1 2 3 3 3 0 Vpu protein UCH PF00443.29 EOO03157.1 - 1e-37 130.1 0.0 1.4e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EOO03157.1 - 2.8e-25 87.8 1.9 1.2e-23 82.6 0.2 2.5 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 EOO03157.1 - 2.7e-23 82.1 12.0 1e-20 73.8 1.5 3.0 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 EOO03157.1 - 6.2e-22 77.1 0.0 3.1e-11 42.9 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 EOO03157.1 - 3.7e-16 59.6 1.9 4.5e-14 52.8 0.0 3.4 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase K-box PF01486.17 EOO03157.1 - 0.035 14.3 0.3 0.096 12.9 0.3 1.7 1 0 0 1 1 1 0 K-box region DUF695 PF05117.12 EOO03157.1 - 0.062 13.5 0.0 0.53 10.5 0.0 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF695) TauD PF02668.16 EOO03158.1 - 3.8e-43 148.2 0.2 5.3e-43 147.7 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2076 PF09849.9 EOO03159.1 - 1.4 8.9 10.4 0.32 11.0 6.9 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) HORMA PF02301.18 EOO03160.1 - 4.3e-26 91.8 0.0 4.9e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 HORMA domain Fer4 PF00037.27 EOO03161.1 - 1.4e-13 50.0 16.5 5.8e-08 32.2 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EOO03161.1 - 9e-13 48.6 10.2 1.5e-12 47.9 10.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EOO03161.1 - 1.9e-10 41.5 7.2 6.9e-05 23.7 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EOO03161.1 - 1.1e-09 38.3 31.2 5.1e-06 26.5 12.1 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 EOO03161.1 - 1.4e-08 34.7 21.4 2.8e-06 27.3 12.3 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EOO03161.1 - 4.1e-08 33.3 10.1 8.7e-08 32.2 10.1 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EOO03161.1 - 5.6e-07 29.9 19.3 0.00019 21.8 11.3 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EOO03161.1 - 1.3e-06 28.2 17.1 0.00038 20.4 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EOO03161.1 - 4.3e-06 26.5 11.8 0.0093 16.0 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EOO03161.1 - 8.2e-06 25.9 11.4 0.00028 21.1 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EOO03161.1 - 0.00024 21.6 11.4 0.037 14.6 12.4 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EOO03161.1 - 0.0059 16.8 5.5 0.75 10.1 0.5 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain ETF_QO PF05187.13 EOO03161.1 - 0.042 14.0 5.2 0.19 11.9 0.4 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_13 PF13370.6 EOO03161.1 - 0.056 14.0 15.1 0.71 10.5 4.3 2.8 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 EOO03161.1 - 0.063 13.5 8.8 1.1 9.4 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EOO03161.1 - 0.22 12.6 15.5 0.4 11.7 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 EOO03161.1 - 0.64 10.9 11.7 2.4 9.0 1.7 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain zf-CCCH PF00642.24 EOO03162.1 - 7.8e-11 41.6 8.5 1.5e-05 24.8 2.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EOO03162.1 - 1.1e-10 41.0 11.9 2e-05 24.2 3.7 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EOO03162.1 - 4e-10 39.4 17.4 7e-05 22.7 4.2 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EOO03162.1 - 2.2e-08 34.7 6.6 0.00013 22.6 0.5 2.3 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 EOO03162.1 - 4.2e-05 23.7 0.2 7.2e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EOO03162.1 - 0.32 11.5 21.8 0.7 10.5 6.4 2.7 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger NifU_N PF01592.16 EOO03163.1 - 1.1e-53 180.7 0.0 1.5e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain Aminotran_1_2 PF00155.21 EOO03165.1 - 9.6e-42 143.4 0.0 1.2e-41 143.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EOO03165.1 - 2.5e-09 36.2 0.0 3.6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EOO03165.1 - 7.6e-07 28.4 0.0 1.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EOO03165.1 - 4.9e-06 26.0 0.0 8.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.7 EOO03165.1 - 8.3e-05 21.5 0.0 0.00091 18.1 0.0 2.0 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase Aminotran_3 PF00202.21 EOO03165.1 - 0.033 12.8 0.0 0.049 12.3 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.17 EOO03165.1 - 0.14 11.5 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.13 EOO03165.1 - 0.2 10.5 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Allinase PrgU PF09627.10 EOO03166.1 - 0.0014 18.5 4.1 3 7.8 0.3 3.8 1 1 1 2 2 2 2 PrgU-like protein Orthopox_B11R PF07033.11 EOO03166.1 - 0.006 16.3 0.6 2.5 8.0 0.1 2.5 1 1 0 2 2 2 2 Orthopoxvirus B11R protein Put_DNA-bind_N PF06971.13 EOO03166.1 - 0.0062 16.5 0.3 35 4.5 0.0 3.9 4 0 0 4 4 4 0 Putative DNA-binding protein N-terminus Eaf7 PF07904.13 EOO03166.1 - 0.0062 16.9 3.2 2.1 8.8 0.3 2.3 1 1 1 2 2 2 2 Chromatin modification-related protein EAF7 V-ATPase_G_2 PF16999.5 EOO03166.1 - 0.013 15.9 0.2 4 7.9 0.1 2.5 1 1 2 3 3 3 0 Vacuolar (H+)-ATPase G subunit Renin_r PF07850.14 EOO03166.1 - 0.016 15.8 6.7 6.7 7.4 0.1 3.3 3 0 0 3 3 3 0 Renin receptor-like protein DUF4227 PF14004.6 EOO03166.1 - 0.028 14.4 0.6 56 3.8 0.0 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF4227) GPHH PF16905.5 EOO03166.1 - 0.057 13.2 4.3 20 5.0 0.0 3.8 4 0 0 4 4 4 0 Voltage-dependent L-type calcium channel, IQ-associated GUCT PF08152.12 EOO03166.1 - 0.13 12.5 0.2 13 6.1 0.0 2.3 1 1 0 2 2 2 0 GUCT (NUC152) domain KIP1 PF07765.12 EOO03166.1 - 0.24 11.6 2.8 57 3.9 0.1 3.5 1 1 3 4 4 4 0 KIP1-like protein VAR1 PF05316.12 EOO03166.1 - 0.63 9.0 4.7 35 3.3 0.4 3.3 1 1 2 3 3 3 0 Mitochondrial ribosomal protein (VAR1) DEAD_2 PF06733.15 EOO03167.1 - 9e-26 90.6 0.0 1.4e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 EOO03167.1 - 7.2e-05 22.9 0.0 0.061 13.3 0.0 2.3 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 EOO03167.1 - 0.0026 17.5 0.0 0.12 12.1 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 EOO03167.1 - 0.012 15.1 0.1 0.74 9.2 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 EOO03167.1 - 0.044 14.1 0.1 6.1 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EOO03167.1 - 0.15 11.6 0.2 0.4 10.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain CBM9_2 PF16011.5 EOO03168.1 - 5.3e-05 23.0 0.3 0.00011 22.0 0.3 1.4 1 1 0 1 1 1 1 Carbohydrate-binding family 9 Amidase PF01425.21 EOO03169.1 - 4.8e-05 22.5 0.0 0.017 14.1 0.0 2.1 2 0 0 2 2 2 2 Amidase Peptidase_S8 PF00082.22 EOO03170.1 - 1.6e-20 73.6 0.0 6.9e-17 61.6 0.0 2.3 1 1 1 2 2 2 2 Subtilase family fn3_5 PF06280.12 EOO03170.1 - 7e-06 26.7 0.1 3.5e-05 24.5 0.0 2.2 2 1 0 2 2 2 1 Fn3-like domain Acetyltransf_1 PF00583.25 EOO03171.1 - 4.7e-13 49.4 0.0 5.9e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EOO03171.1 - 7.1e-13 48.6 0.0 8.8e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EOO03171.1 - 8.7e-12 45.3 0.0 1.3e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EOO03171.1 - 1.4e-05 25.1 0.0 2.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EOO03171.1 - 0.00014 21.8 0.0 0.00033 20.6 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EOO03171.1 - 0.008 16.3 0.0 0.0087 16.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EOO03171.1 - 0.019 15.0 0.0 0.029 14.4 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.24 EOO03172.1 - 1.9e-121 406.1 21.3 2.2e-121 405.9 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO03172.1 - 7e-22 77.8 50.0 1.8e-20 73.2 25.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_16 PF13432.6 EOO03172.1 - 0.0018 18.9 0.2 0.0035 18.0 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat SHR3_chaperone PF08229.11 EOO03172.1 - 0.29 10.1 2.7 2.9 6.9 0.1 2.5 1 1 1 2 2 2 0 ER membrane protein SH3 DUF2370 PF10176.9 EOO03173.1 - 5.5e-92 307.5 0.0 8.2e-92 306.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Aldo_ket_red PF00248.21 EOO03175.1 - 3.5e-42 144.6 0.4 5.2e-40 137.5 0.4 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family HeH PF12949.7 EOO03175.1 - 0.08 12.7 0.0 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 HeH/LEM domain tRNA-synt_1d PF00750.19 EOO03176.1 - 3.7e-66 223.5 0.2 7e-66 222.5 0.2 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EOO03176.1 - 8.4e-13 48.6 0.0 2e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Lipocalin PF00061.23 EOO03176.1 - 0.078 13.2 1.0 0.52 10.5 1.0 2.1 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Transp_cyt_pur PF02133.15 EOO03177.1 - 6.3e-57 193.3 22.6 8e-52 176.5 14.0 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin PrgI PF12666.7 EOO03177.1 - 0.17 12.6 5.9 0.19 12.5 1.7 2.8 2 0 0 2 2 2 0 PrgI family protein Epiglycanin_C PF14654.6 EOO03177.1 - 0.52 10.4 2.9 0.24 11.5 0.2 1.9 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region PCMT PF01135.19 EOO03178.1 - 1.5e-53 181.7 0.0 4.7e-38 131.1 0.0 2.0 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EOO03178.1 - 5.5e-07 29.5 0.0 9.6e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EOO03178.1 - 1.7e-05 24.8 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO03178.1 - 6.3e-05 23.6 0.0 0.00012 22.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EOO03178.1 - 0.0059 16.5 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EOO03178.1 - 0.006 16.0 0.0 0.0092 15.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EOO03178.1 - 0.008 16.8 0.0 0.015 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EOO03178.1 - 0.054 13.0 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 EOO03178.1 - 0.082 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FPN1 PF06963.12 EOO03179.1 - 1.6e-59 201.6 0.1 2e-59 201.3 0.1 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) DEAD PF00270.29 EOO03180.1 - 1.7e-48 164.7 0.0 7.3e-48 162.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EOO03180.1 - 2.9e-33 114.5 0.1 1.2e-30 106.2 0.2 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 EOO03180.1 - 1.5e-05 24.0 0.0 3.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 MAT1 PF06391.13 EOO03180.1 - 0.0031 17.4 20.2 0.0063 16.4 20.2 1.5 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 CMS1 PF14617.6 EOO03180.1 - 0.24 10.7 0.0 0.24 10.7 0.0 3.4 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit TIMELESS PF04821.14 EOO03180.1 - 1.6 7.9 0.0 1.6 7.9 0.0 2.5 2 1 0 2 2 2 0 Timeless protein Suf PF05843.14 EOO03180.1 - 3 7.7 11.8 4.9 7.0 11.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PA26 PF04636.13 EOO03180.1 - 5.4 5.8 11.4 8.6 5.2 11.4 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Rtf2 PF04641.12 EOO03180.1 - 7.6 5.8 25.1 13 5.0 25.1 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger Transp_cyt_pur PF02133.15 EOO03181.1 - 1.8e-99 333.5 38.9 2.1e-99 333.3 38.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Mito_carr PF00153.27 EOO03182.1 - 5e-43 145.0 8.0 1.1e-20 73.4 0.2 4.2 4 1 0 4 4 4 4 Mitochondrial carrier protein Pkinase PF00069.25 EOO03183.1 - 4.3e-43 147.6 0.0 8.2e-40 136.8 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EOO03183.1 - 3.5e-14 52.7 0.0 3.7e-08 33.0 0.0 3.5 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 EOO03183.1 - 0.00016 21.7 0.5 0.0064 16.4 0.1 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EOO03183.1 - 0.0011 17.9 0.0 0.0033 16.3 0.0 1.9 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EOO03183.1 - 0.0064 15.8 0.0 3.7 6.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EOO03183.1 - 0.053 12.9 0.1 0.3 10.4 0.0 2.3 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EOO03183.1 - 0.12 12.0 0.1 0.95 9.0 0.0 2.3 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pes-10 PF07149.11 EOO03183.1 - 0.94 8.5 11.2 1.8 7.5 11.2 1.4 1 0 0 1 1 1 0 Pes-10 Transp_cyt_pur PF02133.15 EOO03184.1 - 4e-15 55.5 30.2 3.9e-13 49.0 30.2 2.2 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Methyltransf_25 PF13649.6 EOO03185.1 - 8.7e-16 58.4 0.0 1.5e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO03185.1 - 6.6e-15 55.2 0.0 8.3e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO03185.1 - 2.5e-12 47.3 0.0 3.9e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EOO03185.1 - 3.3e-12 46.5 0.0 4.6e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO03185.1 - 1.6e-10 41.6 0.0 3.4e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EOO03185.1 - 2.5e-07 30.3 0.0 3.5e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 EOO03185.1 - 0.0005 19.1 0.0 0.00061 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Pox_MCEL PF03291.16 EOO03185.1 - 0.00071 18.8 0.0 0.0015 17.7 0.0 1.4 1 1 0 1 1 1 1 mRNA capping enzyme PrmA PF06325.13 EOO03185.1 - 0.0009 18.7 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EOO03185.1 - 0.0011 18.8 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EOO03185.1 - 0.006 16.6 0.0 0.0074 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EOO03185.1 - 0.03 13.9 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_20 PF12147.8 EOO03185.1 - 0.053 12.7 0.0 0.25 10.4 0.0 1.8 1 1 1 2 2 2 0 Putative methyltransferase NNMT_PNMT_TEMT PF01234.17 EOO03185.1 - 0.063 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family FtsJ PF01728.19 EOO03185.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase N2227 PF07942.12 EOO03185.1 - 0.14 11.4 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein NodS PF05401.11 EOO03185.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) GRIM-19 PF06212.12 EOO03186.1 - 1.8e-23 83.0 0.1 2.9e-23 82.3 0.1 1.3 1 1 0 1 1 1 1 GRIM-19 protein DUF1479 PF07350.12 EOO03187.1 - 5.5e-125 417.4 0.0 6.7e-125 417.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PP-binding PF00550.25 EOO03188.1 - 2.1e-11 44.0 0.1 2.7e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EOO03188.1 - 0.00039 20.6 0.1 0.00053 20.2 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier p450 PF00067.22 EOO03189.1 - 1.1e-73 248.5 0.0 1.5e-73 248.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L27A PF00828.19 EOO03190.1 - 7.5e-21 75.1 0.0 8.5e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Man-6-P_recep PF02157.15 EOO03192.1 - 1.8e-18 66.5 0.0 5.8e-17 61.6 0.0 2.1 2 0 0 2 2 2 2 Mannose-6-phosphate receptor ATG27 PF09451.10 EOO03192.1 - 2.1e-16 60.6 0.1 5e-16 59.3 0.1 1.8 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EOO03192.1 - 6.8e-07 29.4 0.3 0.0008 19.5 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Abhydrolase_3 PF07859.13 EOO03193.1 - 1.7e-06 28.0 0.0 9.2e-06 25.7 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 EOO03193.1 - 0.025 13.5 0.0 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family Aminotran_5 PF00266.19 EOO03194.1 - 1.4e-18 67.0 0.0 2.7e-18 66.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EOO03194.1 - 1.1e-05 24.8 0.0 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.19 EOO03194.1 - 0.012 14.3 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Sec15 PF04091.12 EOO03194.1 - 0.21 11.0 0.0 1.9 7.8 0.0 2.0 2 0 0 2 2 2 0 Exocyst complex subunit Sec15-like ERG4_ERG24 PF01222.17 EOO03195.1 - 2.9e-172 573.3 0.2 3.4e-172 573.1 0.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EOO03195.1 - 8.1e-06 25.5 0.1 2.5e-05 23.9 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Peptidase_S8 PF00082.22 EOO03196.1 - 1.8e-42 145.7 1.0 2.8e-42 145.0 1.0 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EOO03196.1 - 9.9e-08 32.7 0.0 2.3e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 EOO03196.1 - 0.013 15.5 0.0 0.035 14.1 0.0 1.7 1 0 0 1 1 1 0 PA domain DUF4232 PF14016.6 EOO03196.1 - 0.11 12.7 0.0 0.63 10.2 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4232) Zn_clus PF00172.18 EOO03197.1 - 3.8e-08 33.3 13.8 7.4e-08 32.4 13.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.11 EOO03197.1 - 0.13 12.8 0.6 0.27 11.7 0.6 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PTR2 PF00854.21 EOO03198.1 - 1.6e-77 261.0 11.8 2.1e-77 260.6 11.8 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EOO03198.1 - 7.1e-07 28.5 25.6 1.5e-06 27.4 22.0 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Asp PF00026.23 EOO03199.1 - 1.2e-59 202.3 8.1 1.5e-59 202.0 8.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EOO03199.1 - 2.7e-08 34.3 7.1 2.4e-05 24.7 0.1 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EOO03199.1 - 0.0068 16.2 0.1 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Glyco_hydro_3_C PF01915.22 EOO03200.1 - 1.9e-49 168.4 0.0 3.5e-49 167.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EOO03200.1 - 1.6e-40 139.5 0.0 2.3e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EOO03200.1 - 1.2e-15 57.4 0.0 2.4e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF1823 PF08853.11 EOO03200.1 - 0.18 12.0 0.0 7.2 6.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1823) DUF2517 PF10725.9 EOO03201.1 - 0.078 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) ABC_tran PF00005.27 EOO03202.1 - 2.8e-47 160.7 0.0 9.2e-25 87.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EOO03202.1 - 6.6e-26 91.6 29.8 1.5e-21 77.3 15.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EOO03202.1 - 2.1e-10 40.4 5.6 0.0018 17.7 0.0 5.5 5 1 1 6 6 6 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EOO03202.1 - 2.4e-08 33.6 0.6 0.0031 17.2 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 EOO03202.1 - 6.9e-08 31.9 0.0 0.005 15.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EOO03202.1 - 9.5e-08 31.7 0.7 0.013 14.9 0.2 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.17 EOO03202.1 - 9.8e-08 32.4 0.3 0.0082 16.3 0.0 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_21 PF13304.6 EOO03202.1 - 4.2e-07 30.1 0.1 0.16 11.8 0.0 3.3 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EOO03202.1 - 2e-06 28.1 0.1 0.052 13.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EOO03202.1 - 4.3e-06 27.2 0.3 0.044 14.2 0.0 2.9 2 1 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 EOO03202.1 - 4.7e-06 27.3 0.2 0.063 13.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EOO03202.1 - 5.3e-06 26.5 0.1 0.14 12.2 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EOO03202.1 - 4.9e-05 22.7 0.2 0.26 10.6 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 EOO03202.1 - 5.6e-05 23.1 0.3 0.084 12.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 EOO03202.1 - 0.0001 21.9 0.1 0.081 12.4 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 EOO03202.1 - 0.00042 19.9 0.1 0.8 9.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.9 EOO03202.1 - 0.00051 19.1 0.3 0.22 10.4 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.18 EOO03202.1 - 0.00065 19.5 0.9 0.21 11.3 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EOO03202.1 - 0.0013 18.5 0.2 0.15 11.8 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EOO03202.1 - 0.0023 18.5 0.1 1.3 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EOO03202.1 - 0.004 17.3 0.1 5.7 7.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 EOO03202.1 - 0.0057 16.7 0.1 5 7.1 0.0 2.5 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.12 EOO03202.1 - 0.009 15.9 0.1 4.6 7.1 0.0 2.5 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.13 EOO03202.1 - 0.012 14.8 0.1 0.32 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EOO03202.1 - 0.012 16.0 0.0 8.5 6.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Pox_A32 PF04665.12 EOO03202.1 - 0.017 14.6 0.2 7.3 6.0 0.0 2.5 3 0 0 3 3 2 0 Poxvirus A32 protein AAA_15 PF13175.6 EOO03202.1 - 0.017 14.9 0.2 3.6 7.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 EOO03202.1 - 0.036 13.2 0.2 4.1 6.5 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 EOO03202.1 - 0.037 14.4 0.2 5.2 7.4 0.1 2.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EOO03202.1 - 0.042 13.4 0.2 11 5.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EOO03202.1 - 0.043 14.0 0.1 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EOO03202.1 - 0.067 12.3 0.0 5.1 6.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_28 PF13521.6 EOO03202.1 - 0.07 13.4 0.3 1.6 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EOO03202.1 - 0.076 12.9 0.1 5.9 6.8 0.0 2.5 2 0 0 2 2 2 0 NTPase ABC_ATPase PF09818.9 EOO03202.1 - 0.14 10.9 0.6 4 6.1 0.1 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DEAD PF00270.29 EOO03202.1 - 0.15 11.8 0.6 6 6.6 0.0 3.0 4 0 0 4 4 2 0 DEAD/DEAH box helicase ATP_bind_1 PF03029.17 EOO03202.1 - 0.16 11.7 0.4 8.3 6.1 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Sigma54_activat PF00158.26 EOO03202.1 - 0.17 11.6 0.1 1.7 8.3 0.1 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 EOO03202.1 - 0.25 10.7 1.6 8.5 5.6 0.1 3.1 3 0 0 3 3 3 0 KaiC Adeno_IVa2 PF02456.15 EOO03202.1 - 0.25 10.1 0.2 8.2 5.1 0.1 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein APS_kinase PF01583.20 EOO03202.1 - 1 9.2 5.0 8.3 6.3 0.0 3.3 4 0 0 4 4 3 0 Adenylylsulphate kinase SbcCD_C PF13558.6 EOO03202.1 - 1.1 9.5 3.4 45 4.4 0.0 3.7 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Thioesterase PF00975.20 EOO03203.1 - 4.9e-19 69.4 0.0 1.1e-16 61.7 0.0 2.1 2 0 0 2 2 2 2 Thioesterase domain Abhydrolase_6 PF12697.7 EOO03203.1 - 3.1e-06 28.0 0.2 5e-06 27.3 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EOO03203.1 - 0.00011 22.0 0.0 0.00031 20.5 0.0 1.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EOO03203.1 - 0.072 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EOO03203.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thiolase_C PF02803.18 EOO03204.1 - 4.5e-43 145.8 0.4 6.9e-43 145.2 0.4 1.3 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 EOO03204.1 - 2.1e-27 96.1 0.1 3.2e-27 95.5 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain His_Phos_2 PF00328.22 EOO03205.1 - 5.1e-06 26.1 0.3 6.2e-05 22.5 0.0 2.2 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) DUF3493 PF11998.8 EOO03205.1 - 4 7.7 6.8 0.98 9.6 0.6 2.7 2 1 0 2 2 2 0 Low psii accumulation1 / Rep27 AOX PF01786.17 EOO03206.1 - 5.9e-91 303.8 0.0 7.1e-91 303.6 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase Rad60-SLD PF11976.8 EOO03207.1 - 2e-14 53.1 0.3 8.9e-14 51.1 0.3 2.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EOO03207.1 - 0.00016 21.3 0.2 0.035 13.8 0.0 2.4 1 1 1 2 2 2 2 Ubiquitin family TmoB PF06234.12 EOO03207.1 - 0.059 13.5 0.0 0.22 11.7 0.0 2.1 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) eIF3_subunit PF08597.10 EOO03208.1 - 1.4e-72 244.5 28.2 1.8e-72 244.2 28.2 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit CFEM PF05730.11 EOO03209.1 - 4.2e-12 46.0 14.2 4.2e-12 46.0 14.2 1.6 2 0 0 2 2 2 1 CFEM domain Mucin PF01456.17 EOO03209.1 - 0.031 14.3 24.4 0.05 13.6 24.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein adh_short_C2 PF13561.6 EOO03210.1 - 1.2e-34 119.9 3.2 1e-27 97.3 0.3 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO03210.1 - 5.4e-24 84.7 0.1 1.5e-23 83.3 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO03210.1 - 5.8e-05 23.1 0.7 0.00024 21.1 0.1 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EOO03210.1 - 0.023 14.2 0.0 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family PALP PF00291.25 EOO03210.1 - 0.14 11.5 3.3 0.96 8.8 0.1 2.2 1 1 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme zf-C2H2 PF00096.26 EOO03211.1 - 6.4e-05 23.2 0.5 0.52 10.9 0.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EOO03211.1 - 0.025 15.0 0.2 0.26 11.8 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EOO03211.1 - 0.082 13.8 2.8 3.4 8.8 0.0 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EOO03211.1 - 0.97 9.4 2.5 0.64 10.0 0.5 1.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Cupin_2 PF07883.11 EOO03212.1 - 1e-14 54.0 0.1 1.8e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EOO03212.1 - 3.2e-08 33.3 0.1 4.9e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 EOO03212.1 - 5.3e-06 26.0 0.1 8.7e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 EOO03212.1 - 8.6e-05 22.5 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain CENP-C_C PF11699.8 EOO03212.1 - 0.00045 20.4 0.0 0.00071 19.7 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like MannoseP_isomer PF01050.18 EOO03212.1 - 0.0005 20.0 0.0 0.00078 19.4 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_6 PF12852.7 EOO03212.1 - 0.0006 19.6 0.3 0.0015 18.3 0.1 1.6 1 1 0 1 1 1 1 Cupin EutQ PF06249.12 EOO03212.1 - 0.0011 18.7 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ ARD PF03079.14 EOO03212.1 - 0.037 14.2 0.0 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family MFS_1 PF07690.16 EOO03213.1 - 2.7e-26 92.3 30.4 4.1e-26 91.8 30.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO03213.1 - 1.2e-06 27.6 13.9 1.2e-06 27.6 13.9 2.8 3 1 0 4 4 4 1 Sugar (and other) transporter PTR2 PF00854.21 EOO03213.1 - 2.1e-05 23.6 0.5 3.8e-05 22.7 0.3 1.6 1 1 0 1 1 1 1 POT family DUF4191 PF13829.6 EOO03213.1 - 4.7 6.5 5.3 2.7 7.3 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) MDM31_MDM32 PF08118.11 EOO03216.1 - 1.1e-234 780.0 0.0 1.3e-234 779.8 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Trypan_PARP PF05887.11 EOO03217.1 - 0.0035 17.3 30.8 0.0035 17.3 30.8 19.6 7 3 15 22 22 22 3 Procyclic acidic repetitive protein (PARP) KH_8 PF17903.1 EOO03218.1 - 1.7e-06 28.0 0.0 3.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EOO03218.1 - 0.0056 16.5 0.4 0.012 15.4 0.4 1.5 1 0 0 1 1 1 1 KH domain UDG PF03167.19 EOO03220.1 - 4.3e-18 65.8 0.0 1.5e-17 64.0 0.0 2.0 2 1 0 2 2 2 1 Uracil DNA glycosylase superfamily UDPGP PF01704.18 EOO03221.1 - 3.7e-53 180.7 0.0 4.7e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase FAM199X PF15814.5 EOO03222.1 - 5.4 6.0 9.3 9.5 5.2 9.3 1.4 1 0 0 1 1 1 0 Protein family FAM199X CCDC106 PF15794.5 EOO03223.1 - 0.035 13.8 3.5 0.065 12.9 3.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 LMBR1 PF04791.16 EOO03224.1 - 1.1e-18 67.5 18.6 3.7e-18 65.7 2.9 3.0 2 1 1 3 3 3 2 LMBR1-like membrane protein stn_TNFRSF12A PF12191.8 EOO03224.1 - 0.3 11.3 2.0 12 6.1 0.2 3.3 3 0 0 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Mpv17_PMP22 PF04117.12 EOO03225.1 - 6e-23 80.9 0.5 9.5e-23 80.2 0.5 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family TetR_C_20 PF17925.1 EOO03225.1 - 0.027 14.8 0.1 0.17 12.2 0.1 2.1 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HET PF06985.11 EOO03226.1 - 7.5e-25 88.0 0.0 1.8e-24 86.8 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Apolipoprotein PF01442.18 EOO03227.1 - 0.025 14.5 2.2 0.027 14.3 2.2 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain kleA_kleC PF17383.2 EOO03227.1 - 0.045 14.1 0.8 0.082 13.2 0.8 1.5 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A DUF883 PF05957.13 EOO03227.1 - 0.17 12.5 5.8 0.39 11.4 3.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EOO03227.1 - 0.62 10.6 9.5 77 3.9 9.5 2.3 1 1 0 1 1 1 0 YtxH-like protein LEA_4 PF02987.16 EOO03227.1 - 2.7 8.2 13.1 0.8 9.8 7.7 2.6 2 0 0 2 2 2 0 Late embryogenesis abundant protein CsbD PF05532.12 EOO03227.1 - 4.8 7.2 22.8 6.3e+02 0.4 19.2 3.5 2 1 0 2 2 2 0 CsbD-like CPSF_A PF03178.15 EOO03228.1 - 1.9e-65 221.3 0.0 8.5e-65 219.2 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 EOO03228.1 - 3e-17 62.4 0.0 1.6e-16 60.0 0.0 2.0 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term HAD_2 PF13419.6 EOO03229.1 - 1.2e-07 32.0 0.0 1.4e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EOO03229.1 - 1.3e-05 25.6 0.0 4.4e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Epimerase PF01370.21 EOO03230.1 - 2.5e-16 59.9 0.0 5.3e-16 58.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO03230.1 - 7.5e-10 38.7 0.1 0.00091 18.7 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EOO03230.1 - 5e-09 36.1 0.2 7.1e-08 32.3 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 EOO03230.1 - 1.3e-08 34.2 0.0 2.5e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EOO03230.1 - 7.5e-05 22.0 0.0 0.0001 21.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EOO03230.1 - 0.0069 15.6 0.2 0.69 9.0 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein AlaDh_PNT_C PF01262.21 EOO03230.1 - 0.0083 15.4 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SNAP PF14938.6 EOO03230.1 - 0.055 12.9 0.2 0.082 12.3 0.2 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP ZZ PF00569.17 EOO03231.1 - 2.3e-09 36.9 6.7 4.2e-09 36.1 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 EOO03231.1 - 1.7e-08 33.4 5.1 0.00089 18.6 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EOO03231.1 - 5.1e-07 29.1 5.5 0.00031 20.4 0.2 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EOO03231.1 - 1.1e-06 29.0 10.6 2.6e-05 24.6 4.1 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 EOO03231.1 - 0.013 15.3 0.4 4.6 7.2 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair C1_2 PF03107.16 EOO03231.1 - 0.026 14.8 6.4 0.052 13.9 6.4 1.5 1 0 0 1 1 1 0 C1 domain EF-hand_5 PF13202.6 EOO03231.1 - 2.9 7.5 4.2 3.4 7.3 0.3 2.5 2 0 0 2 2 2 0 EF hand DUF3591 PF12157.8 EOO03232.1 - 1.7e-168 560.9 0.1 2.7e-168 560.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 EOO03232.1 - 0.0049 16.9 0.7 0.0084 16.2 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EOO03232.1 - 0.21 11.4 1.7 0.53 10.2 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle Med8 PF10232.9 EOO03232.1 - 4.9 6.7 7.3 0.68 9.5 0.1 2.9 3 0 0 3 3 3 0 Mediator of RNA polymerase II transcription complex subunit 8 ADP_ribosyl_GH PF03747.14 EOO03233.1 - 9.7e-64 215.9 0.3 1.1e-63 215.7 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Pescadillo_N PF06732.11 EOO03234.1 - 5.4e-123 409.9 0.2 1.1e-122 408.9 0.2 1.4 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.26 EOO03234.1 - 7.2e-06 26.3 0.1 0.0001 22.6 0.0 2.6 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Astro_capsid_p PF12226.8 EOO03234.1 - 0.0034 16.6 13.0 0.006 15.8 13.0 1.3 1 0 0 1 1 1 1 Turkey astrovirus capsid protein BRCT_2 PF16589.5 EOO03234.1 - 0.03 14.7 0.0 0.15 12.4 0.0 2.2 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Tom37 PF10568.9 EOO03235.1 - 7.9e-34 116.7 0.7 1.4e-33 115.8 0.7 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EOO03235.1 - 6.4e-13 48.3 0.0 1.8e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EOO03235.1 - 1.1e-05 26.1 0.0 3.5e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 EOO03235.1 - 0.033 14.2 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EOO03235.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Arginase PF00491.21 EOO03236.1 - 2.6e-44 151.8 0.0 2.9e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family PIG-U PF06728.13 EOO03237.1 - 2e-67 227.9 24.9 2.3e-67 227.7 24.9 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 EOO03237.1 - 0.017 14.8 10.1 0.057 13.1 10.0 1.9 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain DHHC PF01529.20 EOO03238.1 - 4.6e-14 52.7 2.7 5.9e-14 52.3 2.7 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF349 PF03993.12 EOO03238.1 - 0.059 13.7 1.1 0.12 12.7 1.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) UPF0183 PF03676.14 EOO03239.1 - 1.1e-50 173.2 0.0 1.8e-33 116.4 0.0 3.6 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) FAD_binding_8 PF08022.12 EOO03240.1 - 3.3e-22 78.6 0.0 6.5e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EOO03240.1 - 3.8e-22 79.1 0.0 6e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EOO03240.1 - 5.4e-20 71.8 11.4 5.4e-20 71.8 11.4 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 EOO03240.1 - 0.053 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EOO03240.1 - 0.13 12.9 0.0 3.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4780 PF16012.5 EOO03240.1 - 0.18 11.2 0.1 0.53 9.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4780) p450 PF00067.22 EOO03241.1 - 1.4e-30 106.5 0.0 1.7e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SRF-TF PF00319.18 EOO03242.1 - 7.1e-24 83.0 0.3 9.5e-24 82.6 0.3 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Lactamase_B PF00753.27 EOO03243.1 - 0.00021 21.3 0.0 0.00032 20.8 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_5 PF14597.6 EOO03243.1 - 0.0017 17.9 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Zn-ribbon_8 PF09723.10 EOO03243.1 - 0.041 14.0 0.4 0.08 13.1 0.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain DUF3231 PF11553.8 EOO03243.1 - 0.06 13.0 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) DZR PF12773.7 EOO03243.1 - 0.11 12.5 0.7 0.21 11.7 0.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon Kinesin PF00225.23 EOO03244.1 - 4.9e-109 364.3 0.4 1.3e-108 362.9 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EOO03244.1 - 5.3e-25 88.1 3.6 6.6e-25 87.8 0.0 3.0 4 0 0 4 4 4 1 Microtubule binding Microtub_bind PF13931.6 EOO03244.1 - 8.8e-05 22.9 0.6 8.8e-05 22.9 0.6 4.7 5 0 0 5 5 5 1 Kinesin-associated microtubule-binding Tox-REase-2 PF15646.6 EOO03244.1 - 5.9 7.1 6.9 3.5 7.8 0.2 3.4 2 1 1 3 3 3 0 Restriction endonuclease fold toxin 2 Myosin_head PF00063.21 EOO03245.1 - 1.8e-236 786.6 8.6 2.2e-236 786.3 8.6 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EOO03245.1 - 1.3e-45 155.4 0.0 2.6e-45 154.4 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EOO03245.1 - 4.1e-13 48.7 0.3 7.7e-13 47.8 0.3 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EOO03245.1 - 2e-11 43.6 0.2 7.1e-11 41.8 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EOO03245.1 - 8e-09 35.1 0.0 1.7e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 EOO03245.1 - 0.0033 17.1 10.2 0.13 12.1 2.2 2.8 1 1 1 2 2 2 2 IQ calmodulin-binding motif SH3_3 PF08239.11 EOO03245.1 - 0.011 16.0 0.4 0.03 14.6 0.4 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain Hpr_kinase_C PF07475.12 EOO03245.1 - 0.017 14.6 0.2 6.3 6.3 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 EOO03245.1 - 0.02 15.2 0.1 0.071 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EOO03245.1 - 0.063 13.7 0.0 0.24 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain SepF PF04472.12 EOO03245.1 - 0.069 13.4 0.0 0.25 11.6 0.0 2.0 1 0 0 1 1 1 0 Cell division protein SepF DUF4145 PF13643.6 EOO03245.1 - 0.081 13.1 0.0 0.67 10.1 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4145) DUF4913 PF16259.5 EOO03245.1 - 0.14 12.3 1.1 0.41 10.7 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) Hexokinase_2 PF03727.16 EOO03246.1 - 1.7e-80 270.0 0.0 2.2e-80 269.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EOO03246.1 - 1.2e-63 214.6 0.0 3.8e-61 206.5 0.0 2.9 2 1 0 2 2 2 1 Hexokinase Pil1 PF13805.6 EOO03247.1 - 1.3e-110 369.0 5.1 1.7e-110 368.7 5.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 VTC PF09359.10 EOO03248.1 - 9.9e-99 330.2 1.3 1.5e-98 329.6 0.0 1.8 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 EOO03248.1 - 1.1e-14 54.6 3.2 2.4e-14 53.5 3.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 EOO03248.1 - 6.2e-13 49.4 10.0 1.8e-05 24.9 0.0 4.1 3 1 1 4 4 4 3 SPX domain Astro_capsid_p PF12226.8 EOO03248.1 - 0.035 13.2 1.3 0.059 12.5 1.3 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Cys_Met_Meta_PP PF01053.20 EOO03249.1 - 1.7e-20 72.9 0.0 3e-20 72.1 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EOO03249.1 - 7.2e-07 28.7 0.0 1.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Clat_adaptor_s PF01217.20 EOO03250.1 - 2e-16 60.2 0.0 8.9e-14 51.6 0.2 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Peptidase_S80 PF07230.11 EOO03250.1 - 0.05 11.9 0.0 0.064 11.5 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) Pkinase PF00069.25 EOO03251.1 - 2.6e-41 141.7 0.0 3.6e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO03251.1 - 1.6e-32 112.8 0.0 2.3e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EOO03251.1 - 0.0077 15.0 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EOO03251.1 - 0.033 13.5 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EOO03251.1 - 0.076 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EOO03251.1 - 0.08 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribophorin_I PF04597.14 EOO03252.1 - 1.1e-156 522.5 0.7 1.3e-156 522.2 0.7 1.0 1 0 0 1 1 1 1 Ribophorin I FAD_binding_3 PF01494.19 EOO03253.1 - 2.3e-18 66.6 0.0 2.9e-10 40.0 0.1 2.1 1 1 1 2 2 2 2 FAD binding domain SE PF08491.10 EOO03253.1 - 0.0019 17.3 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Sua5_yciO_yrdC PF01300.18 EOO03254.1 - 1.2e-51 174.7 0.0 2e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EOO03254.1 - 1.1e-31 110.2 0.1 1.7e-31 109.5 0.1 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding IFT20 PF14931.6 EOO03254.1 - 0.037 14.2 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 MCM PF00493.23 EOO03255.1 - 7.1e-101 336.0 0.0 1.1e-100 335.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EOO03255.1 - 1.1e-39 135.2 1.6 2.1e-39 134.2 1.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EOO03255.1 - 6.6e-29 100.2 4.8 1.8e-28 98.8 4.8 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EOO03255.1 - 1.4e-18 67.4 0.1 5.3e-18 65.5 0.1 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EOO03255.1 - 1.6e-05 24.4 0.0 0.00045 19.6 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EOO03255.1 - 3.9e-05 23.7 0.0 0.00017 21.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EOO03255.1 - 0.00095 19.0 0.0 0.0043 16.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 EOO03255.1 - 0.022 14.6 0.2 0.057 13.3 0.2 1.6 1 0 0 1 1 1 0 AAA lid domain SDA1 PF05285.12 EOO03256.1 - 0.043 13.3 4.0 0.075 12.5 3.8 1.4 2 0 0 2 2 2 0 SDA1 DUF5585 PF17823.1 EOO03256.1 - 0.81 8.6 6.8 1.3 7.9 6.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Complex1_49kDa PF00346.19 EOO03257.1 - 7e-124 412.3 0.0 9.6e-124 411.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EOO03257.1 - 0.022 13.7 0.0 0.042 12.7 0.0 1.4 1 1 0 1 1 1 0 Nickel-dependent hydrogenase BLM10_mid PF16507.5 EOO03258.1 - 5.3e-203 675.4 0.0 4.6e-202 672.3 0.0 2.2 3 0 0 3 3 3 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EOO03258.1 - 3.4e-29 100.6 0.0 1.7e-28 98.4 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 EOO03258.1 - 2.9e-21 75.5 0.0 9.5e-21 73.9 0.0 2.0 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal Arylsulfotran_2 PF14269.6 EOO03260.1 - 1.4e-54 185.5 0.0 2.4e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EOO03260.1 - 1.4e-14 53.8 0.0 2.7e-13 49.6 0.0 2.5 2 1 0 2 2 2 1 Arylsulfotransferase (ASST) TFIIA PF03153.13 EOO03260.1 - 0.59 10.1 24.0 0.98 9.3 24.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.16 EOO03261.1 - 3.8e-24 85.3 17.0 3.8e-24 85.3 17.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M4_C PF02868.15 EOO03262.1 - 1.5e-45 155.1 0.1 5e-45 153.4 0.0 1.9 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 EOO03262.1 - 6.7e-26 91.5 5.5 1.3e-25 90.6 5.5 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain PLN_propep PF16485.5 EOO03262.1 - 1.4e-22 79.1 1.5 3.5e-15 55.4 0.1 2.4 2 0 0 2 2 2 2 Protealysin propeptide Senescence PF06911.12 EOO03262.1 - 0.0091 16.3 0.2 0.29 11.4 0.0 2.3 2 0 0 2 2 2 1 Senescence-associated protein BPL_N PF09825.9 EOO03263.1 - 2.6e-148 494.1 0.0 3.1e-148 493.9 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EOO03263.1 - 1e-19 70.7 0.0 1.6e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 EOO03263.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain p450 PF00067.22 EOO03264.1 - 5.5e-42 144.1 0.2 5.1e-29 101.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Augurin PF15187.6 EOO03264.1 - 0.035 14.3 0.1 0.14 12.3 0.1 1.9 2 0 0 2 2 2 0 Oesophageal cancer-related gene 4 Glyco_transf_92 PF01697.27 EOO03265.1 - 8e-07 29.0 1.5 1.2e-06 28.4 0.9 1.6 1 1 1 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EOO03265.1 - 1.2e-05 25.7 0.2 5.5e-05 23.6 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase family 2 fn2 PF00040.19 EOO03265.1 - 0.07 13.4 0.9 15 5.9 0.1 2.5 2 0 0 2 2 2 0 Fibronectin type II domain p450 PF00067.22 EOO03266.1 - 1.1e-39 136.4 0.0 1.5e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Gpi16 PF04113.14 EOO03267.1 - 8.6e-200 664.9 0.0 1.1e-199 664.6 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component zf-C2H2_4 PF13894.6 EOO03268.1 - 0.25 12.3 2.9 0.57 11.2 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EOO03268.1 - 0.27 11.8 0.2 0.27 11.8 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type ADH_N PF08240.12 EOO03269.1 - 7.5e-17 61.2 0.5 1.8e-16 60.0 0.5 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EOO03269.1 - 2.7e-07 30.6 0.0 7.4e-06 26.0 0.0 2.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase HI0933_like PF03486.14 EOO03269.1 - 0.0059 15.4 0.0 0.0091 14.7 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EOO03269.1 - 0.018 14.3 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fringe PF02434.16 EOO03270.1 - 1.7e-09 37.5 0.0 3.7e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 EOO03270.1 - 1.8e-08 34.1 1.0 4.7e-08 32.8 0.2 2.0 3 0 0 3 3 3 1 Protein of unknown function, DUF604 FMO-like PF00743.19 EOO03271.1 - 1.3e-23 83.3 0.0 2e-16 59.5 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EOO03271.1 - 2.6e-10 40.0 0.0 4.1e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EOO03271.1 - 4e-05 23.0 0.0 0.00017 20.9 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EOO03271.1 - 0.0001 21.6 0.3 0.00029 20.1 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EOO03272.1 - 9.3e-22 77.7 0.0 1.3e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EOO03272.1 - 2.7e-06 26.9 0.4 0.0028 16.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EOO03272.1 - 7e-06 25.9 0.2 0.0011 18.7 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EOO03272.1 - 7.5e-05 23.2 0.2 0.038 14.6 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EOO03272.1 - 0.0057 15.8 0.1 0.0079 15.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EOO03272.1 - 0.093 12.1 0.5 0.17 11.2 0.3 1.6 1 1 1 2 2 2 0 FAD dependent oxidoreductase LUC7 PF03194.15 EOO03273.1 - 6.1e-70 235.7 0.1 7.3e-70 235.5 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF1241 PF06840.11 EOO03273.1 - 0.074 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Ntox28 PF15605.6 EOO03273.1 - 0.13 12.5 0.1 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial toxin 28 DUF4164 PF13747.6 EOO03274.1 - 2e-05 24.8 21.1 0.065 13.5 2.2 3.4 1 1 1 3 3 3 3 Domain of unknown function (DUF4164) Tricorn_C1 PF14684.6 EOO03274.1 - 0.0019 18.2 0.2 0.0036 17.3 0.2 1.4 1 0 0 1 1 1 1 Tricorn protease C1 domain Exonuc_VII_L PF02601.15 EOO03274.1 - 0.0022 17.7 4.3 0.0027 17.3 4.3 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit KxDL PF10241.9 EOO03274.1 - 0.0057 16.9 4.7 0.0057 16.9 4.7 3.2 1 1 0 2 2 2 1 Uncharacterized conserved protein EzrA PF06160.12 EOO03274.1 - 0.0085 14.3 15.1 0.011 14.0 15.1 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA PRKG1_interact PF15898.5 EOO03274.1 - 0.0093 16.8 18.4 1 10.3 0.6 3.1 2 1 0 2 2 2 1 cGMP-dependent protein kinase interacting domain CLZ PF16526.5 EOO03274.1 - 0.013 15.8 17.8 0.065 13.6 1.2 3.5 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TPR_MLP1_2 PF07926.12 EOO03274.1 - 0.014 15.4 20.1 0.02 14.9 9.4 2.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein ABC_tran_CTD PF16326.5 EOO03274.1 - 0.015 15.6 15.1 0.021 15.0 4.7 3.3 2 1 1 3 3 3 0 ABC transporter C-terminal domain Imm49 PF15575.6 EOO03274.1 - 0.021 14.6 1.1 0.023 14.4 0.2 1.5 2 0 0 2 2 1 0 Immunity protein 49 AAA_13 PF13166.6 EOO03274.1 - 0.022 13.4 11.9 0.026 13.2 11.9 1.1 1 0 0 1 1 1 0 AAA domain ADIP PF11559.8 EOO03274.1 - 0.026 14.6 13.5 0.22 11.6 9.0 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 EOO03274.1 - 0.026 13.9 23.2 0.072 12.4 17.8 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BST2 PF16716.5 EOO03274.1 - 0.027 15.1 15.8 0.73 10.5 9.5 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Sec2p PF06428.11 EOO03274.1 - 0.028 14.4 2.6 0.028 14.4 2.6 2.7 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Occludin_ELL PF07303.13 EOO03274.1 - 0.028 15.1 12.6 0.036 14.8 6.7 2.6 1 1 1 2 2 2 0 Occludin homology domain DUF745 PF05335.13 EOO03274.1 - 0.029 14.1 6.1 0.041 13.6 5.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) T3SSipB PF16535.5 EOO03274.1 - 0.03 14.8 3.8 0.03 14.8 3.8 2.2 1 1 1 2 2 2 0 Type III cell invasion protein SipB She9_MDM33 PF05546.11 EOO03274.1 - 0.032 14.1 12.0 0.015 15.1 5.3 2.0 1 1 1 2 2 2 0 She9 / Mdm33 family APG6_N PF17675.1 EOO03274.1 - 0.043 14.3 25.8 0.3 11.6 14.0 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region Zw10 PF06248.13 EOO03274.1 - 0.045 12.3 8.7 0.064 11.8 8.7 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DUF4407 PF14362.6 EOO03274.1 - 0.061 12.7 12.0 0.15 11.4 12.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HSBP1 PF06825.12 EOO03274.1 - 0.09 12.6 0.6 0.09 12.6 0.6 3.8 4 0 0 4 4 4 0 Heat shock factor binding protein 1 Fez1 PF06818.15 EOO03274.1 - 0.14 12.6 18.9 0.33 11.4 10.4 2.1 1 1 0 1 1 1 0 Fez1 HrpB7 PF09486.10 EOO03274.1 - 0.14 12.5 7.7 0.36 11.2 7.6 1.6 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Spectrin PF00435.21 EOO03274.1 - 0.16 12.5 16.6 0.62 10.6 6.2 2.4 1 1 1 2 2 2 0 Spectrin repeat TACC_C PF05010.14 EOO03274.1 - 0.17 11.7 20.2 0.28 11.0 20.2 1.3 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal VSG_B PF13206.6 EOO03274.1 - 0.23 10.7 6.4 0.28 10.4 6.4 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain MscS_porin PF12795.7 EOO03274.1 - 0.25 10.8 13.9 1.5 8.3 13.9 1.9 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain HemX PF04375.14 EOO03274.1 - 0.3 10.4 13.4 2 7.6 0.9 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Laminin_II PF06009.12 EOO03274.1 - 0.32 11.0 9.3 3 7.8 4.1 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF5339 PF17274.2 EOO03274.1 - 0.44 11.4 13.2 3.9 8.4 0.2 3.7 2 2 1 3 3 3 0 Family of unknown function (DUF5339) Snapin_Pallidin PF14712.6 EOO03274.1 - 0.48 10.9 16.9 0.93 10.0 5.8 2.4 1 1 1 2 2 2 0 Snapin/Pallidin DUF4200 PF13863.6 EOO03274.1 - 0.53 10.7 23.4 0.77 10.2 6.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.12 EOO03274.1 - 0.54 10.3 3.4 6.9 6.7 1.9 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4201 PF13870.6 EOO03274.1 - 0.56 9.9 23.2 0.28 10.9 11.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Nup54 PF13874.6 EOO03274.1 - 0.57 10.3 8.4 0.47 10.5 5.0 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DHR10 PF18595.1 EOO03274.1 - 0.69 10.0 22.3 1.9 8.6 16.9 2.5 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain ATG16 PF08614.11 EOO03274.1 - 0.73 10.0 19.2 3.8 7.7 10.6 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 EOO03274.1 - 0.76 9.8 23.7 0.97 9.5 12.8 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cluap1 PF10234.9 EOO03274.1 - 0.78 9.1 17.7 0.69 9.3 7.6 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF4094 PF13334.6 EOO03274.1 - 0.88 10.0 11.3 4 7.9 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) BLOC1_2 PF10046.9 EOO03274.1 - 0.9 9.9 16.1 3.8 7.9 3.7 2.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 EOO03274.1 - 0.99 8.2 23.1 1.8 7.4 11.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein GIY-YIG PF01541.24 EOO03274.1 - 1.3 9.4 3.7 7.9 6.8 0.3 2.3 2 0 0 2 2 2 0 GIY-YIG catalytic domain Golgin_A5 PF09787.9 EOO03274.1 - 1.6 8.1 21.6 29 4.0 21.6 2.0 1 1 0 1 1 1 0 Golgin subfamily A member 5 ZapB PF06005.12 EOO03274.1 - 1.8 9.1 14.3 2.8 8.5 5.8 2.9 1 1 1 2 2 2 0 Cell division protein ZapB Ead_Ea22 PF13935.6 EOO03274.1 - 1.8 9.2 13.9 5.7 7.6 11.8 2.1 1 1 1 2 2 2 0 Ead/Ea22-like protein TMPIT PF07851.13 EOO03274.1 - 2.5 7.2 17.2 1.1 8.5 5.9 2.0 1 1 1 2 2 2 0 TMPIT-like protein HIP1_clath_bdg PF16515.5 EOO03274.1 - 2.5 8.7 19.6 2.5 8.8 11.2 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4349 PF14257.6 EOO03274.1 - 3 7.2 8.8 12 5.3 7.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) LMBR1 PF04791.16 EOO03274.1 - 4.2 6.2 7.7 5.1 5.9 7.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 EOO03274.1 - 4.3 7.4 13.8 0.48 10.5 3.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 EOO03274.1 - 4.6 5.0 15.9 0.49 8.3 6.5 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 EOO03274.1 - 4.9 7.2 23.2 1.6 8.7 4.1 3.3 2 1 0 2 2 2 0 Prefoldin subunit SLATT_5 PF18160.1 EOO03274.1 - 5.3 6.3 6.7 16 4.7 6.1 2.0 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 FlxA PF14282.6 EOO03274.1 - 5.3 7.1 16.5 1.7 8.7 8.6 2.7 1 1 2 3 3 3 0 FlxA-like protein UPF0242 PF06785.11 EOO03274.1 - 5.6 7.0 22.7 2.8 8.0 12.2 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Phage_GPO PF05929.11 EOO03274.1 - 6.1 6.4 11.7 12 5.4 8.6 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Fzo_mitofusin PF04799.13 EOO03274.1 - 6.8 6.2 14.9 8.6 5.9 6.0 2.1 1 1 1 2 2 2 0 fzo-like conserved region FapA PF03961.13 EOO03274.1 - 6.9 5.1 19.1 0.35 9.4 7.5 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF4446 PF14584.6 EOO03274.1 - 7.9 6.5 12.4 0.45 10.5 3.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) DUF3450 PF11932.8 EOO03274.1 - 9.2 5.5 17.3 5.9 6.1 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) PilO PF04350.13 EOO03274.1 - 9.5 6.4 10.3 0.89 9.7 1.1 2.6 1 1 1 2 2 2 0 Pilus assembly protein, PilO Asparaginase_2 PF01112.18 EOO03275.1 - 1.6e-57 194.9 0.4 7.3e-27 94.2 0.0 3.1 3 0 0 3 3 3 3 Asparaginase Glyco_hydro_43 PF04616.14 EOO03276.1 - 1.5e-49 168.8 6.5 2e-49 168.4 6.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1080 PF06439.11 EOO03276.1 - 2.7e-05 24.4 0.3 5e-05 23.5 0.3 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) CBM_4_9 PF02018.17 EOO03276.1 - 0.011 16.0 1.3 0.19 12.0 0.2 2.5 2 0 0 2 2 2 0 Carbohydrate binding domain DUF1412 PF07203.11 EOO03276.1 - 0.46 10.7 2.8 4.7 7.5 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1412) Tim17 PF02466.19 EOO03277.1 - 5.9e-33 113.6 8.6 7.2e-33 113.3 8.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Sugar_tr PF00083.24 EOO03278.1 - 2.1e-80 270.8 26.8 2.4e-80 270.6 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO03278.1 - 1.3e-15 57.2 23.5 1.3e-15 57.2 23.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EOO03279.1 - 1.3e-42 146.1 59.4 4.6e-41 140.9 60.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EOO03279.1 - 7.8e-12 44.4 31.7 3.1e-11 42.4 29.5 2.2 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ECSCR PF15820.5 EOO03279.1 - 2.8 7.8 4.0 14 5.6 1.0 2.8 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator AA_permease_2 PF13520.6 EOO03280.1 - 2.2e-20 72.9 36.2 2.5e-20 72.7 36.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EOO03280.1 - 5.8e-07 28.5 27.6 7.8e-07 28.0 27.6 1.1 1 0 0 1 1 1 1 Amino acid permease VIT1 PF01988.19 EOO03280.1 - 0.19 11.6 6.7 0.31 10.9 1.3 2.5 2 0 0 2 2 2 0 VIT family Tfb2 PF03849.14 EOO03281.1 - 3.8e-137 457.0 0.0 5.1e-137 456.6 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EOO03281.1 - 5.5e-24 84.4 2.1 1.1e-23 83.4 2.1 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EOO03281.1 - 6.6e-05 23.1 0.1 0.00028 21.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Yip1 PF04893.17 EOO03282.1 - 3.5e-07 30.1 11.1 6e-05 22.8 5.9 2.4 2 1 0 2 2 2 2 Yip1 domain TMEM252 PF15664.5 EOO03282.1 - 2.2 8.0 3.9 7.2 6.3 0.6 3.2 3 1 0 3 3 3 0 Transmembrane protein 252 family ADH_zinc_N PF00107.26 EOO03283.1 - 2e-10 40.7 0.0 3.3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EOO03283.1 - 7.1e-05 23.9 0.0 0.00022 22.3 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AAA PF00004.29 EOO03284.1 - 2.4e-18 66.8 0.0 4.5e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EOO03284.1 - 0.0003 20.8 0.0 0.00067 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EOO03284.1 - 0.00061 20.1 0.1 0.0042 17.4 0.0 2.2 1 1 1 2 2 2 1 AAA domain Zot PF05707.12 EOO03284.1 - 0.00063 19.4 0.0 0.0079 15.9 0.0 2.3 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_16 PF13191.6 EOO03284.1 - 0.00073 20.0 0.0 0.002 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 EOO03284.1 - 0.0096 15.0 0.0 0.031 13.4 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.6 EOO03284.1 - 0.016 15.8 0.0 0.05 14.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EOO03284.1 - 0.037 13.8 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 EOO03284.1 - 0.042 14.0 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 EOO03284.1 - 0.046 13.4 0.2 0.56 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EOO03284.1 - 0.049 13.4 0.1 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EOO03284.1 - 0.06 13.6 0.1 0.23 11.7 0.0 2.0 2 1 0 2 2 1 0 AAA domain AAA_14 PF13173.6 EOO03284.1 - 0.066 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EOO03284.1 - 0.091 12.1 0.2 0.29 10.4 0.2 1.9 1 1 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 EOO03284.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Peptidase_M66 PF10462.9 EOO03285.1 - 1.3e-05 24.3 1.3 2.6e-05 23.3 1.3 1.4 1 0 0 1 1 1 1 Peptidase M66 BiPBP_C PF06832.12 EOO03285.1 - 7.7e-05 22.7 0.1 0.00031 20.7 0.0 2.1 2 0 0 2 2 2 1 Penicillin-Binding Protein C-terminus Family Reprolysin_5 PF13688.6 EOO03285.1 - 0.007 16.5 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EOO03285.1 - 0.0091 15.7 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like BNR PF02012.20 EOO03285.1 - 0.072 13.1 0.4 0.33 11.1 0.4 2.2 1 0 0 1 1 1 0 BNR/Asp-box repeat Reprolysin_3 PF13582.6 EOO03285.1 - 0.11 13.0 0.0 0.3 11.6 0.0 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like TB2_DP1_HVA22 PF03134.19 EOO03286.1 - 8.9e-26 89.6 9.4 1.4e-25 89.0 9.4 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Sugar_tr PF00083.24 EOO03287.1 - 3.7e-75 253.5 28.2 4.3e-75 253.3 28.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO03287.1 - 2.7e-15 56.2 48.9 1.9e-12 46.8 26.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.12 EOO03288.1 - 7.1e-21 74.1 7.1 1.7e-20 72.9 7.1 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EOO03288.1 - 9.2e-19 67.7 0.0 1.9e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EOO03288.1 - 3.1e-07 31.5 0.0 4.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EOO03288.1 - 0.00029 20.2 0.3 0.00047 19.6 0.3 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EOO03288.1 - 0.0041 16.4 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UQ_con PF00179.26 EOO03289.1 - 1.3e-10 41.1 0.0 3.1e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Complex1_LYR PF05347.15 EOO03289.1 - 2.4e-10 40.3 0.0 4e-09 36.4 0.0 2.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EOO03289.1 - 0.001 19.8 0.3 0.075 13.8 0.0 2.8 3 0 0 3 3 3 1 Complex1_LYR-like RWD PF05773.22 EOO03289.1 - 0.0057 16.9 0.1 0.032 14.5 0.0 2.2 2 0 0 2 2 2 1 RWD domain Plug_translocon PF10559.9 EOO03289.1 - 0.1 12.4 0.2 0.24 11.3 0.2 1.7 1 0 0 1 1 1 0 Plug domain of Sec61p RCC1 PF00415.18 EOO03290.1 - 4.2e-64 213.0 0.2 1.4e-11 44.8 0.0 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EOO03290.1 - 2.1e-45 151.7 13.0 6.6e-11 41.7 0.0 6.6 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 EOO03290.1 - 0.054 13.3 1.0 11 5.9 0.1 3.7 4 0 0 4 4 4 0 Peptidase family C25, C terminal ig-like domain Nucleoporin_N PF08801.11 EOO03290.1 - 0.21 10.3 0.0 2.2 6.9 0.0 2.4 2 1 1 3 3 3 0 Nup133 N terminal like DAO PF01266.24 EOO03291.1 - 1.1e-53 183.1 0.9 1.3e-53 182.9 0.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF5472 PF17566.2 EOO03291.1 - 0.01 15.8 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5472) NAD_binding_9 PF13454.6 EOO03291.1 - 0.012 15.6 0.1 0.31 11.0 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EOO03291.1 - 0.02 14.2 0.0 0.1 11.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EOO03291.1 - 0.042 13.1 0.2 0.18 11.0 0.2 1.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EOO03291.1 - 0.044 14.0 0.1 0.044 14.0 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 EOO03291.1 - 0.2 10.2 0.0 0.46 9.0 0.0 1.5 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.17 EOO03291.1 - 0.2 10.8 0.7 0.47 9.7 0.2 1.7 1 1 1 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 EOO03291.1 - 2.2 7.3 11.0 0.046 12.8 1.2 2.4 2 1 0 2 2 2 0 FAD binding domain VIT1 PF01988.19 EOO03292.1 - 1.4e-70 237.5 1.3 1.6e-70 237.3 1.3 1.0 1 0 0 1 1 1 1 VIT family Orai-1 PF07856.12 EOO03292.1 - 0.089 12.5 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Mediator of CRAC channel activity GlpM PF06942.12 EOO03292.1 - 0.19 12.2 6.0 0.51 10.8 0.4 3.0 3 1 0 3 3 3 0 GlpM protein TraQ PF09679.10 EOO03292.1 - 0.2 11.6 1.0 0.53 10.2 0.4 2.1 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) SLATT_fungal PF18142.1 EOO03292.1 - 1.4 8.9 3.2 18 5.4 0.0 2.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain p450 PF00067.22 EOO03293.1 - 4.7e-35 121.2 0.0 5.3e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PAN_2 PF08276.11 EOO03294.1 - 0.012 15.7 1.8 0.017 15.3 1.8 1.3 1 0 0 1 1 1 0 PAN-like domain Crystall_3 PF08964.10 EOO03294.1 - 0.027 14.6 0.1 0.091 12.9 0.0 1.8 1 1 1 2 2 2 0 Beta/Gamma crystallin BetaGal_dom2 PF10435.9 EOO03295.1 - 2.5e-61 206.7 2.0 3.1e-61 206.4 2.0 1.1 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 Glyco_hydro_35 PF01301.19 EOO03295.1 - 1.2e-23 84.2 0.2 1.9e-23 83.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 DHDPS PF00701.22 EOO03296.1 - 1.8e-42 145.1 0.0 2.4e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Peptidase_S9 PF00326.21 EOO03297.1 - 0.0015 18.0 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EOO03297.1 - 0.0026 17.7 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 EOO03297.1 - 0.0032 16.2 0.0 0.011 14.4 0.0 1.8 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 EOO03297.1 - 0.0052 16.3 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 EOO03297.1 - 0.049 13.3 0.1 0.18 11.4 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 EOO03297.1 - 0.13 11.5 0.0 1 8.6 0.0 2.0 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EOO03298.1 - 1.8e-06 27.6 0.0 3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EOO03298.1 - 4.9e-06 27.3 6.4 4.9e-06 27.3 6.4 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EOO03298.1 - 5.4e-06 26.2 0.0 2.5e-05 24.0 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EOO03298.1 - 0.00027 20.3 0.0 0.00045 19.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EOO03298.1 - 0.00052 19.9 0.1 0.00095 19.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EOO03298.1 - 0.00099 18.8 1.1 0.0043 16.7 0.1 2.4 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 EOO03298.1 - 0.0032 17.1 0.3 0.02 14.5 0.3 2.1 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.12 EOO03298.1 - 0.0079 14.9 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 EOO03298.1 - 0.047 13.2 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 EOO03298.1 - 0.05 12.5 0.0 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 EOO03298.1 - 0.054 12.0 0.0 0.09 11.3 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II PhoPQ_related PF10142.9 EOO03298.1 - 0.17 10.5 0.2 0.25 9.9 0.2 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Ank_2 PF12796.7 EOO03299.1 - 3.7e-59 197.3 8.3 2.3e-14 53.7 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EOO03299.1 - 1.2e-49 166.1 3.1 1.2e-09 38.5 0.0 8.1 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 EOO03299.1 - 7.9e-48 158.9 10.2 3.2e-07 30.5 0.0 9.4 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.6 EOO03299.1 - 7.6e-44 147.2 9.0 2.5e-11 43.6 0.0 5.8 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EOO03299.1 - 2.7e-41 134.8 2.4 0.00049 20.3 0.0 9.3 9 0 0 9 9 9 8 Ankyrin repeat Corona_nucleoca PF00937.18 EOO03299.1 - 0.015 14.3 1.1 0.025 13.6 1.1 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PEGA PF08308.11 EOO03299.1 - 0.21 11.5 0.2 26 4.8 0.0 3.6 4 0 0 4 4 4 0 PEGA domain VWA_3_C PF18571.1 EOO03299.1 - 0.28 11.1 4.9 6.1 6.8 0.1 4.7 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain OPT PF03169.15 EOO03300.1 - 5.7e-87 292.8 20.3 3.5e-77 260.5 13.9 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Methyltransf_23 PF13489.6 EOO03301.1 - 4.6e-14 52.6 0.0 8.8e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO03301.1 - 1.1e-08 35.6 0.0 2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO03301.1 - 3.7e-07 30.8 0.0 2.1e-06 28.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO03301.1 - 9.5e-07 29.4 0.0 5.4e-06 27.0 0.0 2.2 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO03301.1 - 2.2e-05 24.3 0.0 3.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EOO03301.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DRE2_N PF16803.5 EOO03301.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus Band_7 PF01145.25 EOO03302.1 - 1.3e-30 106.7 1.0 2.6e-30 105.7 1.0 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EOO03302.1 - 1.9e-24 85.5 0.6 5.5e-24 84.0 0.6 1.9 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 EOO03302.1 - 0.013 14.8 0.3 0.02 14.2 0.3 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein AnmK PF03702.14 EOO03303.1 - 1e-76 258.5 0.0 6.9e-74 249.1 0.0 2.0 1 1 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Peptidase_M22 PF00814.25 EOO03303.1 - 0.13 11.9 0.0 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Glycoprotease family Glyco_hydro_10 PF00331.20 EOO03304.1 - 4e-104 348.2 0.4 4.8e-104 347.9 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Frankia_peptide PF14407.6 EOO03304.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. ABC_tran PF00005.27 EOO03305.1 - 9.1e-11 42.4 0.0 7.9e-07 29.7 0.0 2.5 1 1 1 2 2 2 2 ABC transporter SMC_N PF02463.19 EOO03305.1 - 1.4e-05 24.6 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EOO03305.1 - 0.056 13.2 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF4185 PF13810.6 EOO03306.1 - 6.8e-13 48.5 6.4 9.4e-13 48.1 6.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) ADH_N PF08240.12 EOO03307.1 - 1.3e-26 92.6 0.2 2.4e-26 91.7 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EOO03307.1 - 1.2e-14 54.4 0.2 2.1e-14 53.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EOO03307.1 - 1.4e-11 44.3 0.2 1.2e-05 24.9 0.1 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 EOO03307.1 - 0.019 15.0 0.1 0.054 13.6 0.1 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N_2 PF13602.6 EOO03307.1 - 0.095 13.8 0.0 0.19 12.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MTS PF05175.14 EOO03307.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain NAD_binding_8 PF13450.6 EOO03307.1 - 0.17 12.1 1.2 0.47 10.7 0.7 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NACHT_N PF17100.5 EOO03308.1 - 1.4e-70 237.6 1.7 2.1e-70 237.0 1.7 1.3 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 EOO03308.1 - 3.9e-13 49.6 0.1 8.3e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EOO03308.1 - 4.5e-07 30.4 0.3 4.5e-07 30.4 0.3 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EOO03308.1 - 0.0013 19.0 0.0 0.0044 17.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AFG1_ATPase PF03969.16 EOO03308.1 - 0.0041 16.1 0.4 0.01 14.7 0.0 1.8 2 0 0 2 2 2 1 AFG1-like ATPase DUF2075 PF09848.9 EOO03308.1 - 0.0096 15.2 0.0 0.023 13.9 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEC-1_N PF04625.13 EOO03308.1 - 0.02 13.9 3.4 0.031 13.3 3.4 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region KAP_NTPase PF07693.14 EOO03308.1 - 0.022 14.0 0.5 0.075 12.3 0.1 2.0 2 1 1 3 3 3 0 KAP family P-loop domain ATPase_2 PF01637.18 EOO03308.1 - 0.023 14.6 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EOO03308.1 - 0.027 14.2 0.2 0.3 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Nsp1_C PF05064.13 EOO03308.1 - 0.028 14.2 0.2 0.07 12.9 0.2 1.6 1 0 0 1 1 1 0 Nsp1-like C-terminal region Latarcin PF10279.9 EOO03308.1 - 0.029 14.8 0.5 0.15 12.4 0.2 2.4 2 0 0 2 2 1 0 Latarcin precursor TsaE PF02367.17 EOO03308.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DDHD PF02862.17 EOO03308.1 - 0.052 13.7 2.4 0.038 14.1 0.7 1.6 2 0 0 2 2 2 0 DDHD domain RNA_helicase PF00910.22 EOO03308.1 - 0.091 13.2 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.15 EOO03308.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_C_3 PF13625.6 EOO03309.1 - 0.049 13.8 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Fn3_assoc PF13287.6 EOO03310.1 - 4.7e-12 45.9 8.4 2.1e-11 43.8 3.8 2.6 2 0 0 2 2 2 1 Fn3 associated CHB_HEX_C_1 PF13290.6 EOO03310.1 - 3.9e-10 39.6 4.7 3.9e-10 39.6 4.7 3.0 2 0 0 2 2 2 1 Chitobiase/beta-hexosaminidase C-terminal domain F5_F8_type_C PF00754.25 EOO03310.1 - 4.4e-08 33.3 2.4 1.1e-06 28.7 0.3 3.1 2 1 1 3 3 3 1 F5/8 type C domain Beta-lactamase PF00144.24 EOO03311.1 - 1.4e-10 40.9 0.0 1.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Esterase_phd PF10503.9 EOO03312.1 - 1.3e-19 70.6 0.3 2.6e-19 69.6 0.3 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EOO03312.1 - 2.7e-12 46.6 0.6 3.9e-12 46.1 0.6 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 EOO03312.1 - 2e-06 27.0 1.3 2.7e-06 26.5 1.3 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EOO03312.1 - 0.03 14.2 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Erf4 PF10256.9 EOO03313.1 - 0.093 12.8 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family SoxZ PF08770.11 EOO03313.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.5 1 1 0 1 1 1 0 Sulphur oxidation protein SoxZ MFS_1 PF07690.16 EOO03313.1 - 0.44 9.4 8.5 0.39 9.6 7.2 1.5 2 0 0 2 2 2 0 Major Facilitator Superfamily AA_permease PF00324.21 EOO03314.1 - 4.1e-112 375.2 46.8 5.1e-112 374.9 46.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EOO03314.1 - 1e-28 100.4 48.0 1.2e-28 100.1 48.0 1.1 1 0 0 1 1 1 1 Amino acid permease Pec_lyase_C PF00544.19 EOO03315.1 - 3.4e-42 144.4 8.0 4.6e-42 144.0 8.0 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EOO03315.1 - 1.6e-05 24.8 20.5 0.00058 19.7 2.3 2.4 1 1 1 2 2 2 2 Right handed beta helix region Epimerase PF01370.21 EOO03316.1 - 5.4e-14 52.2 0.0 6.8e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EOO03316.1 - 3.4e-08 33.6 0.4 3.4e-08 33.6 0.4 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EOO03316.1 - 1.3e-07 31.5 0.9 6.5e-07 29.1 0.2 2.0 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EOO03316.1 - 1.1e-06 28.4 0.1 0.00024 20.6 0.0 2.3 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EOO03316.1 - 7.1e-05 21.9 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EOO03316.1 - 0.00096 18.7 0.1 0.0018 17.7 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EOO03316.1 - 0.0014 17.8 0.0 0.0038 16.4 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Gly-zipper_YMGG PF13441.6 EOO03316.1 - 2.8 7.8 9.6 10 5.9 9.6 2.1 1 1 0 1 1 1 0 YMGG-like Gly-zipper p450 PF00067.22 EOO03317.1 - 3.1e-76 257.0 0.0 3.7e-76 256.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EOO03318.1 - 1.3e-29 103.1 0.0 1.7e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03318.1 - 3.6e-28 98.7 0.0 4.5e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO03318.1 - 4.3e-09 36.5 0.0 6e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Sulfotransfer_4 PF17784.1 EOO03319.1 - 1.9e-47 161.9 1.9 1.9e-47 161.9 1.9 1.4 2 0 0 2 2 2 1 Sulfotransferase domain PI-PLC-X PF00388.19 EOO03320.1 - 1e-47 161.4 0.0 1.5e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EOO03320.1 - 2e-36 124.9 0.0 3.2e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain YL1 PF05764.13 EOO03320.1 - 0.021 15.0 2.2 0.034 14.3 2.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein TFIIF_alpha PF05793.12 EOO03320.1 - 0.043 12.4 3.6 0.064 11.9 3.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-B_dimeris PF09026.10 EOO03320.1 - 0.4 11.1 4.8 0.2 12.1 0.7 2.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain adh_short PF00106.25 EOO03321.1 - 1.2e-38 132.5 2.2 1.8e-38 132.0 2.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03321.1 - 7.7e-29 100.9 1.3 1.7e-28 99.8 1.3 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EOO03321.1 - 8e-07 28.7 0.0 7.5e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 EOO03321.1 - 2.6e-05 23.9 0.1 6.2e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO03321.1 - 0.00012 22.0 0.1 0.00019 21.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_2 PF03446.15 EOO03321.1 - 0.00056 20.1 0.2 0.0013 19.0 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.15 EOO03321.1 - 0.0019 18.0 0.3 0.0035 17.2 0.3 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein ApbA PF02558.16 EOO03321.1 - 0.013 15.2 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EOO03321.1 - 0.015 15.9 0.1 0.032 14.8 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EOO03321.1 - 0.019 14.9 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EOO03321.1 - 0.021 13.9 0.1 0.066 12.3 0.1 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain ADH_zinc_N PF00107.26 EOO03321.1 - 0.048 13.6 0.2 0.12 12.4 0.2 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PALP PF00291.25 EOO03321.1 - 0.078 12.4 0.7 0.13 11.7 0.7 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Epimerase PF01370.21 EOO03321.1 - 0.12 11.9 0.1 0.19 11.2 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Toluene_X PF03349.16 EOO03321.1 - 0.15 10.6 0.2 0.2 10.2 0.2 1.1 1 0 0 1 1 1 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) Neur PF00064.18 EOO03322.1 - 0.032 13.0 0.1 0.044 12.5 0.1 1.2 1 0 0 1 1 1 0 Neuraminidase TANGO2 PF05742.12 EOO03323.1 - 5.5e-68 229.7 0.1 3.5e-53 181.2 0.0 2.0 2 0 0 2 2 2 2 Transport and Golgi organisation 2 2OG-FeII_Oxy PF03171.20 EOO03324.1 - 1.8e-18 66.9 0.0 2.4e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_47 PF01532.20 EOO03325.1 - 6.4e-175 582.5 0.0 7.2e-175 582.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 EOO03325.1 - 0.023 13.8 0.1 3.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 EOO03325.1 - 0.065 11.7 0.0 1.1 7.7 0.0 2.6 2 1 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 dCMP_cyt_deam_1 PF00383.23 EOO03326.1 - 2e-08 34.0 0.0 2.9e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EOO03326.1 - 1.5e-07 31.3 0.0 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EOO03326.1 - 0.084 12.9 0.2 0.9 9.6 0.2 2.1 1 1 0 1 1 1 0 Bd3614-like deaminase p450 PF00067.22 EOO03327.1 - 6.5e-29 101.0 0.0 7.9e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease PF00324.21 EOO03328.1 - 7.1e-96 321.7 29.1 8.3e-96 321.4 29.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EOO03328.1 - 2e-32 112.6 30.9 2.3e-32 112.4 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease Macro PF01661.21 EOO03329.1 - 1.2e-07 31.7 0.0 1.7e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Macro domain bZIP_1 PF00170.21 EOO03330.1 - 5.5e-07 29.6 5.5 1.3e-06 28.4 5.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor DUF4778 PF16008.5 EOO03330.1 - 1.6 8.7 8.8 2.4 8.2 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) AT_hook PF02178.19 EOO03330.1 - 2.3 8.3 6.2 2.6 8.2 1.0 2.8 2 0 0 2 2 2 0 AT hook motif 4HBT PF03061.22 EOO03331.1 - 0.00068 19.9 0.0 0.001 19.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily HgmA PF04209.13 EOO03332.1 - 8.4e-139 462.9 0.1 9.5e-139 462.8 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Thymidylat_synt PF00303.19 EOO03333.1 - 2.2e-108 361.4 0.0 2.6e-108 361.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Aldolase_II PF00596.21 EOO03334.1 - 2.1e-48 164.7 0.0 2.7e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MFS_1 PF07690.16 EOO03335.1 - 4.6e-27 94.9 36.8 1.3e-26 93.4 36.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily AnmK PF03702.14 EOO03336.1 - 1.5e-75 254.6 0.0 1.7e-75 254.4 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase AMP-binding PF00501.28 EOO03337.1 - 5.2e-75 252.6 0.0 1.2e-73 248.1 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EOO03337.1 - 1.7e-73 247.4 0.0 2.9e-73 246.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 EOO03337.1 - 5.3e-69 233.0 0.0 8.3e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 EOO03337.1 - 2.4e-52 178.0 0.2 4.2e-52 177.2 0.2 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EOO03337.1 - 3.3e-50 170.5 0.0 1.2e-48 165.5 0.0 2.6 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 EOO03337.1 - 6.5e-32 110.7 0.0 6.2e-31 107.5 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein Acyl_transf_1 PF00698.21 EOO03337.1 - 2.3e-30 106.2 0.0 4e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.12 EOO03337.1 - 1.1e-19 70.9 0.0 2.9e-19 69.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EOO03337.1 - 2.8e-15 56.4 6.5 4.3e-07 30.2 0.2 4.1 5 0 0 5 5 2 2 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 EOO03337.1 - 6.8e-14 51.9 0.0 1.7e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EOO03337.1 - 8.4e-14 52.0 0.0 1.4e-12 48.0 0.0 2.9 3 0 0 3 3 3 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 EOO03337.1 - 1.2e-13 51.1 0.0 5.4e-10 39.1 0.0 2.7 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 EOO03337.1 - 2e-13 50.9 0.0 8.2e-13 48.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EOO03337.1 - 2.5e-13 49.9 0.0 8.6e-12 44.9 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_11 PF08241.12 EOO03337.1 - 1.6e-12 47.9 0.0 5.2e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ketoacyl-synt_C PF02801.22 EOO03337.1 - 4e-12 46.2 0.3 6.6e-05 22.9 0.2 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain Methyltransf_23 PF13489.6 EOO03337.1 - 1e-08 35.2 0.0 3.7e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EOO03337.1 - 5.6e-05 22.6 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 EOO03337.1 - 0.0013 18.2 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 EOO03337.1 - 0.0014 18.1 0.0 2.1 7.7 0.0 3.0 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NodS PF05401.11 EOO03337.1 - 0.012 15.2 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) 3Beta_HSD PF01073.19 EOO03337.1 - 0.063 12.3 0.0 0.17 10.8 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.9 EOO03337.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase NmrA PF05368.13 EOO03338.1 - 4.6e-31 108.2 0.0 8.3e-31 107.3 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO03338.1 - 1.5e-09 38.0 0.0 2.4e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EOO03338.1 - 0.0066 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EOO03338.1 - 0.012 16.1 0.0 0.021 15.3 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EOO03338.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sugar_tr PF00083.24 EOO03339.1 - 8e-78 262.3 7.0 9.6e-78 262.0 7.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO03339.1 - 2.3e-29 102.4 39.4 1.1e-23 83.8 21.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Keratin_assoc PF09775.9 EOO03339.1 - 0.087 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 OATP PF03137.20 EOO03339.1 - 0.17 10.1 4.2 0.48 8.6 4.1 1.9 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ank_2 PF12796.7 EOO03340.1 - 3.4e-58 194.2 0.0 4.6e-09 36.7 0.0 6.6 5 1 2 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EOO03340.1 - 5.9e-42 141.5 0.0 2.4e-06 28.0 0.0 11.4 6 5 7 14 14 14 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EOO03340.1 - 3.8e-39 128.2 0.7 0.078 13.6 0.0 14.4 14 0 0 14 14 14 9 Ankyrin repeat Ank_5 PF13857.6 EOO03340.1 - 6.3e-39 131.5 0.1 0.00023 21.4 0.0 9.9 6 4 4 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 EOO03340.1 - 5.6e-32 108.8 0.0 0.056 13.9 0.0 14.1 13 2 1 14 14 14 7 Ankyrin repeat Ad_Cy_reg PF16701.5 EOO03340.1 - 0.011 15.5 0.1 1.2 8.9 0.2 3.7 4 0 0 4 4 4 0 Adenylate cyclase regulatory domain Helo_like_N PF17111.5 EOO03342.1 - 3.7e-07 29.7 2.5 6.2e-06 25.7 2.5 2.1 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 EOO03342.1 - 0.00013 22.2 0.4 0.0002 21.5 0.4 1.3 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF1465 PF07323.12 EOO03342.1 - 0.003 17.4 0.1 0.0038 17.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1465) TMF_DNA_bd PF12329.8 EOO03342.1 - 0.0066 16.4 1.9 0.0091 16.0 1.9 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 EOO03342.1 - 0.0077 15.2 1.1 0.0099 14.8 1.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.6 EOO03342.1 - 0.014 14.1 0.9 0.019 13.6 0.9 1.2 1 0 0 1 1 1 0 AAA domain HMMR_N PF15905.5 EOO03342.1 - 0.016 14.7 0.5 0.02 14.4 0.5 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal zf-C4H2 PF10146.9 EOO03342.1 - 0.018 15.4 0.4 0.022 15.1 0.4 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Lebercilin PF15619.6 EOO03342.1 - 0.024 14.3 0.2 0.031 13.9 0.2 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Casc1_N PF15927.5 EOO03342.1 - 0.026 14.2 0.3 0.036 13.8 0.3 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus RmuC PF02646.16 EOO03342.1 - 0.028 13.6 0.5 0.038 13.1 0.5 1.2 1 0 0 1 1 1 0 RmuC family FliJ PF02050.16 EOO03342.1 - 0.032 14.4 0.1 0.052 13.8 0.1 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4140 PF13600.6 EOO03342.1 - 0.038 14.4 1.1 0.42 11.1 0.2 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) HrpB7 PF09486.10 EOO03342.1 - 0.047 14.1 1.0 0.36 11.2 0.1 2.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) MscS_porin PF12795.7 EOO03342.1 - 0.052 13.1 1.1 0.074 12.6 1.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF2203 PF09969.9 EOO03342.1 - 0.054 14.2 0.4 0.087 13.6 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Fez1 PF06818.15 EOO03342.1 - 0.058 13.8 0.2 0.06 13.8 0.2 1.1 1 0 0 1 1 1 0 Fez1 AATF-Che1 PF13339.6 EOO03342.1 - 0.064 13.9 0.8 0.086 13.5 0.8 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Bacillus_HBL PF05791.11 EOO03342.1 - 0.068 13.0 0.7 0.098 12.5 0.7 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Flagellin_N PF00669.20 EOO03342.1 - 0.31 11.2 4.2 0.55 10.3 1.0 2.0 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region Asp PF00026.23 EOO03343.1 - 3.2e-76 256.8 13.4 3.9e-76 256.5 13.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EOO03343.1 - 1.7e-13 51.2 4.5 3.1e-06 27.5 0.1 3.0 2 2 1 3 3 3 2 Xylanase inhibitor N-terminal Transp_cyt_pur PF02133.15 EOO03344.1 - 2.9e-54 184.5 30.7 3.5e-54 184.2 30.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF962 PF06127.11 EOO03344.1 - 0.18 11.9 1.7 0.45 10.6 0.1 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF962) MR_MLE_C PF13378.6 EOO03345.1 - 4.9e-54 183.2 0.2 6.5e-54 182.8 0.2 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EOO03345.1 - 2.2e-20 73.0 0.0 4.9e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Pyr_redox_2 PF07992.14 EOO03346.1 - 3.3e-24 85.7 0.0 4.9e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EOO03346.1 - 3.4e-14 53.1 0.1 6e-14 52.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EOO03346.1 - 1.9e-07 30.7 0.0 3.9e-07 29.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EOO03346.1 - 5e-05 23.0 0.1 0.016 14.8 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EOO03346.1 - 0.00085 18.3 0.0 0.15 10.8 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase K_oxygenase PF13434.6 EOO03346.1 - 0.002 17.3 0.0 0.0034 16.6 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EOO03346.1 - 0.0046 16.1 0.0 0.097 11.7 0.0 2.0 1 1 1 2 2 2 1 Lycopene cyclase protein ApbA PF02558.16 EOO03346.1 - 0.05 13.3 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EOO03346.1 - 0.084 13.1 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 EOO03346.1 - 0.14 10.8 0.1 2.2 6.9 0.1 2.1 1 1 1 2 2 2 0 HI0933-like protein DUF1996 PF09362.10 EOO03347.1 - 1e-56 192.5 1.0 1.5e-56 192.0 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) FAD_binding_3 PF01494.19 EOO03348.1 - 1.1e-19 71.0 0.2 1.7e-18 67.0 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EOO03348.1 - 5.5e-07 29.7 2.4 0.026 14.5 0.2 3.1 2 1 1 3 3 3 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EOO03348.1 - 0.00013 21.0 1.5 0.02 13.8 0.5 2.2 1 1 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 EOO03348.1 - 0.00027 20.3 2.0 0.075 12.2 0.4 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EOO03348.1 - 0.00037 20.7 0.3 0.0013 18.9 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EOO03348.1 - 0.0084 15.7 2.4 0.0084 15.7 2.4 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EOO03348.1 - 0.016 14.3 2.2 0.027 13.6 1.3 1.8 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 EOO03348.1 - 0.052 12.8 0.2 0.086 12.1 0.2 1.2 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 EOO03348.1 - 0.077 12.3 0.1 0.81 8.9 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Mgm101p PF06420.12 EOO03349.1 - 1.5e-84 281.7 0.0 2e-84 281.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Dak1 PF02733.17 EOO03350.1 - 2.3e-101 338.8 3.7 2.6e-101 338.6 2.9 1.4 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 EOO03350.1 - 8.4e-46 156.0 0.1 1.4e-45 155.3 0.1 1.4 1 0 0 1 1 1 1 DAK2 domain AP3D1 PF06375.11 EOO03351.1 - 0.075 13.3 1.9 2.9 8.1 0.5 2.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 FMO-like PF00743.19 EOO03352.1 - 0.013 14.0 0.1 0.87 7.9 0.0 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 EOO03352.1 - 0.019 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EOO03352.1 - 0.019 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.6 EOO03352.1 - 0.07 12.3 0.0 1.8 7.6 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EOO03352.1 - 0.16 11.2 0.0 1.2 8.3 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.13 EOO03353.1 - 8e-36 123.7 0.0 9.9e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO03353.1 - 2.9e-20 72.9 0.1 3.4e-20 72.7 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EOO03353.1 - 1.1e-05 25.0 0.1 3.7e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EOO03353.1 - 0.029 14.3 0.0 0.081 12.8 0.1 1.7 2 0 0 2 2 2 0 KR domain 3Beta_HSD PF01073.19 EOO03353.1 - 0.033 13.2 0.0 0.099 11.6 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EOO03353.1 - 0.065 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EOO03353.1 - 0.19 12.0 0.5 3.7 7.8 0.5 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Peptidase_A4 PF01828.17 EOO03355.1 - 8.5e-82 273.7 17.8 1.1e-81 273.3 17.8 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF4920 PF16267.5 EOO03355.1 - 0.093 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4920) adh_short PF00106.25 EOO03356.1 - 1.8e-52 177.7 0.3 2.2e-52 177.4 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03356.1 - 1.8e-45 155.3 0.1 2.4e-45 154.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO03356.1 - 6.8e-13 48.9 1.7 1.4e-12 47.9 1.7 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO03356.1 - 0.00013 21.5 0.3 0.00028 20.4 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 EOO03356.1 - 0.0093 15.9 0.4 0.019 14.9 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_transf_5 PF08323.11 EOO03356.1 - 0.011 15.4 0.0 0.49 10.0 0.0 2.3 2 1 0 2 2 2 0 Starch synthase catalytic domain Exotox-A_cataly PF09009.10 EOO03356.1 - 0.071 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A catalytic RmlD_sub_bind PF04321.17 EOO03356.1 - 0.18 10.9 0.9 0.42 9.7 0.4 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain 3HCDH_N PF02737.18 EOO03356.1 - 0.23 11.3 0.5 0.38 10.6 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 EOO03357.1 - 3.5e-25 88.6 0.0 4.6e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03357.1 - 2.7e-15 56.6 0.0 3.3e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PHO4 PF01384.20 EOO03359.1 - 6.9e-100 334.4 16.5 7.9e-100 334.2 16.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family UPF0444 PF15475.6 EOO03359.1 - 0.54 10.6 8.2 1.3 9.4 0.6 2.7 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 FAM117 PF15388.6 EOO03360.1 - 0.011 15.2 0.3 0.014 14.8 0.3 1.2 1 0 0 1 1 1 0 Protein Family FAM117 adh_short PF00106.25 EOO03362.1 - 5.8e-22 78.1 0.0 7.6e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03362.1 - 6.3e-14 52.1 0.0 9.5e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO03362.1 - 1.6e-09 37.9 0.1 2.1e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EOO03362.1 - 2.2e-05 23.7 0.0 3.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EOO03362.1 - 0.0053 16.3 0.0 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EOO03362.1 - 0.0059 16.7 0.1 0.015 15.4 0.1 1.7 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.8 EOO03362.1 - 0.015 15.0 0.1 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.17 EOO03362.1 - 0.065 13.8 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF885 PF05960.11 EOO03363.1 - 1.3e-46 160.4 0.0 1.9e-46 159.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Nuc_sug_transp PF04142.15 EOO03364.1 - 1.2e-92 310.5 4.4 1.6e-92 310.0 4.4 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EOO03364.1 - 8.3e-07 29.3 25.0 0.00034 20.8 3.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EOO03364.1 - 3.4e-05 23.2 11.3 0.00033 20.0 11.3 2.3 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 EOO03364.1 - 0.00032 20.1 11.5 0.028 13.8 0.8 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family Cu-oxidase_2 PF07731.14 EOO03365.1 - 1.2e-34 119.0 0.6 1.5e-34 118.7 0.6 1.2 1 0 0 1 1 1 1 Multicopper oxidase T4_Rnl2_C PF18043.1 EOO03366.1 - 0.025 14.7 7.2 1.9 8.7 6.5 2.4 1 1 0 1 1 1 0 T4 RNA ligase 2 C-terminal KELK PF15796.5 EOO03366.1 - 0.027 14.9 1.5 0.04 14.4 1.2 1.4 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase EST1 PF10374.9 EOO03366.1 - 0.1 13.2 2.0 0.16 12.6 2.0 1.3 1 0 0 1 1 1 0 Telomerase activating protein Est1 Ribosomal_S13 PF00416.22 EOO03366.1 - 0.11 12.9 1.1 0.13 12.6 1.1 1.2 1 0 0 1 1 1 0 Ribosomal protein S13/S18 Mon2_C PF16206.5 EOO03367.1 - 0.00073 17.8 0.0 0.0009 17.5 0.0 1.1 1 0 0 1 1 1 1 C-terminal region of Mon2 protein DUF687 PF05095.12 EOO03367.1 - 0.13 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF687) HET PF06985.11 EOO03368.1 - 2.3e-32 112.4 0.0 3.9e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TetR_C_31 PF17940.1 EOO03368.1 - 0.51 10.6 2.9 2.3 8.4 0.4 2.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain 2-Hacid_dh_C PF02826.19 EOO03369.1 - 6.6e-54 182.0 0.0 1.1e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EOO03369.1 - 1.9e-17 63.2 0.0 2.3e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EOO03369.1 - 5.6e-07 29.9 0.0 1.4e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Prp19 PF08606.11 EOO03369.1 - 0.035 14.1 0.1 0.064 13.3 0.1 1.4 1 0 0 1 1 1 0 Prp19/Pso4-like F420_oxidored PF03807.17 EOO03369.1 - 0.046 14.3 0.0 0.094 13.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 EOO03369.1 - 0.086 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox_3 PF13738.6 EOO03370.1 - 1.8e-17 63.5 0.0 6.8e-16 58.4 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EOO03370.1 - 2.5e-15 55.9 0.0 9.9e-15 53.9 0.0 1.9 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EOO03370.1 - 2e-13 50.2 0.1 3e-12 46.3 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EOO03370.1 - 1.3e-12 47.6 0.0 5.2e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EOO03370.1 - 8.4e-10 38.9 0.2 3.1e-06 27.3 0.1 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EOO03370.1 - 4.4e-06 26.5 0.3 0.17 11.4 0.0 3.2 4 0 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EOO03370.1 - 1.1e-05 24.3 0.1 0.067 11.9 0.1 2.5 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 EOO03370.1 - 4.5e-05 23.0 0.0 6.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EOO03370.1 - 4.5e-05 22.8 0.0 8.3e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EOO03370.1 - 0.00015 22.0 0.0 0.00069 19.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EOO03370.1 - 0.00039 19.6 0.2 0.6 9.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 EOO03370.1 - 0.0017 17.7 0.2 0.036 13.3 0.1 2.7 3 0 0 3 3 3 1 FAD binding domain Amino_oxidase PF01593.24 EOO03370.1 - 0.0099 15.2 0.0 0.14 11.4 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EOO03370.1 - 0.019 14.1 0.0 0.039 13.0 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Pam16 PF03656.13 EOO03371.1 - 8e-33 113.2 0.3 9.8e-33 112.9 0.3 1.0 1 0 0 1 1 1 1 Pam16 Sun2_CC2 PF18580.1 EOO03371.1 - 0.15 12.3 0.7 0.49 10.7 0.1 2.1 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 Cu_amine_oxid PF01179.20 EOO03372.1 - 3.8e-161 536.6 0.0 4.7e-161 536.3 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EOO03372.1 - 2.5e-22 79.2 0.6 1.2e-21 77.0 0.1 2.2 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EOO03372.1 - 2e-12 47.2 0.1 3.3e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain OPT PF03169.15 EOO03373.1 - 7.1e-84 282.6 20.9 1.3e-68 232.2 11.5 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Ank_2 PF12796.7 EOO03373.1 - 3.9e-14 53.0 0.0 1.1e-13 51.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EOO03373.1 - 3.1e-11 42.5 0.1 1.7e-06 27.9 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EOO03373.1 - 1.2e-09 38.1 0.0 9e-06 25.9 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EOO03373.1 - 5.4e-09 36.4 0.3 6.6e-08 32.9 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EOO03373.1 - 8.9e-09 35.5 0.1 0.00082 19.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) IPU_b_solenoid PF18783.1 EOO03374.1 - 0.036 14.1 0.6 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 Isopullulanase beta-solenoid repeat MCRA PF06100.11 EOO03375.1 - 4e-220 731.8 0.0 4.8e-220 731.5 0.0 1.0 1 0 0 1 1 1 1 MCRA family NAD_binding_8 PF13450.6 EOO03375.1 - 7.1e-08 32.6 0.0 3.1e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EOO03375.1 - 6.7e-05 22.6 0.0 0.0011 18.6 0.0 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EOO03375.1 - 0.006 15.9 0.0 0.39 9.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MvaI_BcnI PF15515.6 EOO03375.1 - 0.01 15.7 0.1 0.02 14.7 0.1 1.5 1 1 0 1 1 1 0 MvaI/BcnI restriction endonuclease family NAD_binding_9 PF13454.6 EOO03375.1 - 0.075 13.0 0.0 1.2 9.1 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EOO03375.1 - 0.23 10.7 0.0 0.43 9.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain TPR_12 PF13424.6 EOO03376.1 - 1.5e-07 31.6 1.8 0.028 14.7 0.4 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EOO03376.1 - 1.6e-06 28.5 2.1 2.9 8.4 0.1 5.0 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EOO03376.1 - 5e-06 26.2 1.5 0.0057 16.7 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EOO03376.1 - 7.9e-05 22.6 0.2 0.13 12.6 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EOO03376.1 - 0.006 16.0 1.2 9.4 5.5 0.0 3.1 1 1 2 3 3 3 1 MalT-like TPR region TPR_9 PF13371.6 EOO03376.1 - 0.011 15.9 0.8 12 6.2 0.0 4.1 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EOO03376.1 - 0.013 16.2 0.9 38 5.5 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 EOO03376.1 - 0.015 15.6 1.2 5.8 7.3 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EOO03376.1 - 0.016 15.0 1.1 9 6.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EOO03376.1 - 0.026 15.1 0.2 11 6.9 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EOO03376.1 - 0.041 13.9 0.1 12 6.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2007 PF09413.10 EOO03376.1 - 0.12 12.5 0.0 0.74 10.0 0.0 2.3 2 1 1 3 3 3 0 Putative prokaryotic signal transducing protein TPR_1 PF00515.28 EOO03376.1 - 0.15 12.0 0.0 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M20 PF01546.28 EOO03377.1 - 8.6e-22 77.8 0.0 1.9e-21 76.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 EOO03377.1 - 1.1e-07 32.4 18.7 0.15 13.0 0.0 8.0 8 1 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO03377.1 - 2e-05 24.8 0.6 0.68 10.3 0.0 4.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M28 PF04389.17 EOO03377.1 - 8.9e-05 22.3 0.0 0.001 18.8 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.14 EOO03377.1 - 0.00016 21.6 0.0 0.00032 20.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain PQQ_3 PF13570.6 EOO03377.1 - 0.046 14.2 0.3 4.7 7.8 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain Ge1_WD40 PF16529.5 EOO03377.1 - 0.1 11.6 0.1 0.44 9.5 0.0 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CNH PF00780.22 EOO03377.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 CNH domain MFS_1 PF07690.16 EOO03378.1 - 7e-35 120.6 46.8 1.4e-34 119.6 46.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EOO03378.1 - 2.4e-19 69.2 14.8 2.5e-18 65.8 14.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EOO03378.1 - 1.5e-10 40.6 9.9 1.5e-10 40.6 9.9 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter Neisseria_TspB PF05616.13 EOO03378.1 - 0.023 13.2 5.0 0.031 12.7 5.0 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Trypan_PARP PF05887.11 EOO03378.1 - 0.93 9.5 7.7 2 8.4 7.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MFS_1 PF07690.16 EOO03379.1 - 1.8e-33 116.0 24.0 1.8e-33 116.0 24.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sulfatase PF00884.23 EOO03380.1 - 4.8e-42 144.4 0.1 2.7e-40 138.7 0.0 2.5 2 1 0 2 2 2 1 Sulfatase DUF4976 PF16347.5 EOO03380.1 - 1.1e-06 28.9 0.1 1.1e-06 28.9 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 EOO03380.1 - 1.5e-05 24.8 0.2 0.00014 21.6 0.2 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 EOO03380.1 - 0.009 16.8 0.8 0.016 16.0 0.1 1.8 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 EOO03380.1 - 0.099 11.2 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF1501 PF07394.12 EOO03380.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Lipase_GDSL_2 PF13472.6 EOO03381.1 - 3.1e-07 31.0 0.0 3.7e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EOO03381.1 - 0.00043 20.3 0.0 0.00064 19.7 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FAM91_N PF14647.6 EOO03381.1 - 0.034 13.5 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 FAM91 N-terminus Glutaredoxin PF00462.24 EOO03382.1 - 1.5e-15 57.1 0.8 4.1e-15 55.7 0.0 2.1 3 0 0 3 3 3 1 Glutaredoxin GST_N_3 PF13417.6 EOO03382.1 - 0.00067 20.0 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Herpes_UL25 PF01499.16 EOO03382.1 - 0.24 9.9 1.1 0.33 9.4 1.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family RNase_T PF00929.24 EOO03383.1 - 8.4e-08 32.9 0.0 2.7e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 Exonuclease Trehalose_recp PF06151.13 EOO03383.1 - 0.3 9.6 0.0 1.2 7.7 0.0 1.7 2 0 0 2 2 2 0 Trehalose receptor Cys_Met_Meta_PP PF01053.20 EOO03385.1 - 3.5e-141 470.2 0.0 4e-141 470.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EOO03385.1 - 2.1e-07 30.5 0.1 3e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EOO03385.1 - 1.3e-05 24.4 0.7 1.9e-05 23.8 0.1 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EOO03385.1 - 0.00042 19.7 1.0 0.00075 18.9 1.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Big_3_5 PF16640.5 EOO03385.1 - 1.2 9.3 6.7 3.1 8.1 4.4 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Ribosomal_S19 PF00203.21 EOO03386.1 - 3.1e-33 113.5 0.3 4.4e-33 113.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 ADH_N PF08240.12 EOO03388.1 - 2.3e-11 43.5 0.0 5.5e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EOO03388.1 - 3e-06 27.3 0.1 5.7e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EOO03388.1 - 0.098 12.6 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase S-AdoMet_synt_C PF02773.16 EOO03389.1 - 4.8e-66 221.0 0.9 7.4e-66 220.4 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EOO03389.1 - 2.5e-45 153.6 0.0 4.9e-45 152.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EOO03389.1 - 4.7e-44 149.1 1.1 9.2e-44 148.2 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain ATP_bind_1 PF03029.17 EOO03390.1 - 2.3e-73 246.9 0.0 3.6e-73 246.3 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 EOO03390.1 - 0.0004 20.2 0.0 0.00071 19.4 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 EOO03390.1 - 0.00062 19.8 0.0 0.0013 18.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EOO03390.1 - 0.0037 17.0 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EOO03390.1 - 0.0068 16.8 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 EOO03390.1 - 0.0071 16.9 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EOO03390.1 - 0.0091 16.1 0.0 0.01 15.9 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 EOO03390.1 - 0.018 15.2 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EOO03390.1 - 0.023 15.1 0.1 0.63 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EOO03390.1 - 0.024 14.9 0.0 0.044 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EOO03390.1 - 0.028 13.7 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Septin GTP_EFTU PF00009.27 EOO03390.1 - 0.032 13.8 0.0 4.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Thymidylate_kin PF02223.17 EOO03390.1 - 0.038 13.7 0.0 6.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase AAA_16 PF13191.6 EOO03390.1 - 0.041 14.3 0.0 0.18 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 EOO03390.1 - 0.052 13.2 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 EOO03390.1 - 0.058 13.3 0.1 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 EOO03390.1 - 0.066 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EOO03390.1 - 0.069 13.7 0.0 0.19 12.2 0.0 1.7 2 0 0 2 2 2 0 ABC transporter KAP_NTPase PF07693.14 EOO03390.1 - 0.11 11.7 0.0 0.12 11.6 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain PPV_E1_C PF00519.17 EOO03390.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase TRADD_N PF09034.10 EOO03390.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 TRADD, N-terminal domain NACHT PF05729.12 EOO03390.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 EOO03390.1 - 0.16 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TPR_1 PF00515.28 EOO03392.1 - 1.3e-24 84.9 4.1 4.8e-08 32.5 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EOO03392.1 - 1.8e-22 77.5 7.0 9.2e-07 28.5 0.1 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 EOO03392.1 - 1e-16 61.3 8.5 1e-05 26.0 2.9 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 EOO03392.1 - 2.4e-16 59.1 6.0 1.1e-07 31.4 0.0 4.9 3 2 2 5 5 5 3 TPR repeat TPR_14 PF13428.6 EOO03392.1 - 4e-15 55.2 8.4 1.3e-05 25.6 0.1 5.7 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EOO03392.1 - 7e-15 53.9 0.7 2.7e-05 24.0 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EOO03392.1 - 1.5e-13 50.1 3.7 0.0022 18.3 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EOO03392.1 - 1.7e-12 47.6 6.8 0.0019 18.6 0.0 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 EOO03392.1 - 1.9e-12 46.2 2.8 0.0058 16.6 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 EOO03392.1 - 9.2e-11 41.7 0.6 0.0025 17.9 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EOO03392.1 - 1.2e-10 41.5 8.6 0.016 15.5 0.3 4.4 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_20 PF14561.6 EOO03392.1 - 2e-09 37.6 3.2 0.0017 18.6 0.0 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EOO03392.1 - 1.9e-08 34.4 1.9 0.89 10.3 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 EOO03392.1 - 0.00024 20.4 1.1 0.55 9.4 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EOO03392.1 - 0.00029 21.0 4.7 0.081 13.2 0.3 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 CRISPR_Cse2 PF09485.10 EOO03392.1 - 0.0048 17.4 3.0 0.0099 16.4 0.2 2.4 2 0 0 2 2 2 1 CRISPR-associated protein Cse2 (CRISPR_cse2) TPR_3 PF07720.12 EOO03392.1 - 0.0055 16.7 0.4 2 8.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat PBD PF00786.28 EOO03392.1 - 0.012 16.0 0.4 0.037 14.4 0.0 2.0 2 0 0 2 2 1 0 P21-Rho-binding domain TPR_10 PF13374.6 EOO03392.1 - 0.056 13.3 7.7 0.057 13.3 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1641 PF07849.11 EOO03392.1 - 0.067 13.1 0.2 0.19 11.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) Amidase PF01425.21 EOO03393.1 - 1e-93 314.7 0.0 1.6e-93 314.2 0.0 1.3 1 0 0 1 1 1 1 Amidase Apq12 PF12716.7 EOO03394.1 - 3.9e-14 52.3 11.9 6.4e-14 51.6 11.9 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis BTP PF05232.12 EOO03394.1 - 0.57 10.3 6.4 1.4 9.0 6.5 1.5 1 1 0 1 1 1 0 Chlorhexidine efflux transporter p450 PF00067.22 EOO03395.1 - 2.5e-50 171.6 0.0 3e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zip PF02535.22 EOO03396.1 - 6.7e-64 216.2 5.0 8.1e-64 215.9 5.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Brix PF04427.18 EOO03398.1 - 3.9e-41 141.3 0.0 5.4e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain Glyco_hydro_53 PF07745.13 EOO03399.1 - 9.9e-108 360.1 0.2 1.1e-107 359.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cupin_2 PF07883.11 EOO03400.1 - 0.047 13.4 0.1 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Cupin domain RRM_1 PF00076.22 EOO03401.1 - 5.3e-36 122.3 0.0 4.2e-18 64.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EOO03401.1 - 0.00076 19.3 0.0 0.26 11.1 0.0 2.5 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 EOO03401.1 - 0.0077 16.3 0.0 3 8.0 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Limkain-b1 PF11608.8 EOO03401.1 - 0.018 15.1 0.1 0.17 12.0 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 RRM_5 PF13893.6 EOO03401.1 - 0.043 13.4 0.0 0.25 10.9 0.0 2.0 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 EOO03402.1 - 3.8e-31 108.3 44.2 6e-31 107.7 44.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MMR_HSR1 PF01926.23 EOO03404.1 - 6.9e-09 35.8 0.3 1.8e-08 34.5 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EOO03404.1 - 2.2e-08 33.7 0.1 4.1e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EOO03404.1 - 0.00011 22.2 0.3 0.00027 20.9 0.3 1.6 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 EOO03404.1 - 0.00029 20.9 11.8 0.16 12.0 0.2 3.6 2 2 2 4 4 4 2 Dynamin family Septin PF00735.18 EOO03404.1 - 0.00041 19.7 0.6 0.00076 18.8 0.0 1.8 2 0 0 2 2 2 1 Septin AAA_23 PF13476.6 EOO03404.1 - 0.00064 20.3 10.0 0.84 10.1 8.4 2.1 2 0 0 2 2 2 2 AAA domain SRPRB PF09439.10 EOO03404.1 - 0.003 17.0 3.1 0.013 15.0 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EOO03404.1 - 0.0065 17.0 3.6 0.018 15.5 0.0 2.6 2 1 1 3 3 3 1 ABC transporter Jnk-SapK_ap_N PF09744.9 EOO03404.1 - 0.0067 16.7 8.9 0.012 15.9 8.9 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 FeoB_N PF02421.18 EOO03404.1 - 0.01 15.3 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Tropomyosin_1 PF12718.7 EOO03404.1 - 0.055 13.6 11.3 0.093 12.9 11.3 1.3 1 0 0 1 1 1 0 Tropomyosin like NACHT PF05729.12 EOO03404.1 - 0.078 12.9 0.1 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Gtr1_RagA PF04670.12 EOO03404.1 - 0.098 12.0 0.7 0.15 11.4 0.0 1.7 2 1 1 3 3 3 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 EOO03404.1 - 0.099 12.4 0.0 0.099 12.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EOO03404.1 - 0.11 12.9 0.4 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 EOO03404.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AvrB_AvrC PF05394.11 EOO03404.1 - 0.12 11.6 0.4 0.17 11.0 0.4 1.2 1 0 0 1 1 1 0 Avirulence protein Fungal_trans_2 PF11951.8 EOO03404.1 - 0.16 10.7 0.1 0.64 8.8 0.1 1.8 2 0 0 2 2 2 0 Fungal specific transcription factor domain EMC3_TMCO1 PF01956.16 EOO03404.1 - 0.22 11.2 0.8 0.37 10.5 0.8 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF2229 PF09989.9 EOO03404.1 - 0.38 10.4 1.6 0.6 9.7 1.6 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) FAM184 PF15665.5 EOO03404.1 - 0.58 9.9 10.9 0.55 10.0 9.6 1.5 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B DUF2203 PF09969.9 EOO03404.1 - 2.4 8.9 5.5 1.1e+02 3.6 5.4 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF87 PF01935.17 EOO03404.1 - 4.3 7.4 12.0 0.34 10.9 0.2 2.4 2 1 0 2 2 2 0 Helicase HerA, central domain zf-RanBP PF00641.18 EOO03404.1 - 7.4 6.0 6.9 1.8 8.0 1.7 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others FAM76 PF16046.5 EOO03404.1 - 9.1 5.5 11.5 17 4.6 11.5 1.4 1 0 0 1 1 1 0 FAM76 protein Sugar_tr PF00083.24 EOO03405.1 - 4.9e-57 193.8 11.9 4.3e-42 144.5 9.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EOO03405.1 - 3.1e-21 75.7 25.0 1.4e-18 67.0 18.6 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EOO03405.1 - 0.006 15.0 3.3 0.0086 14.5 3.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 EOO03405.1 - 0.0062 15.5 1.5 0.01 14.8 1.5 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM OATP PF03137.20 EOO03405.1 - 0.018 13.3 4.7 0.0076 14.6 1.7 1.9 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Cu_amine_oxid PF01179.20 EOO03406.1 - 3e-161 536.9 0.0 3.7e-161 536.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 EOO03406.1 - 2.3e-07 31.0 0.0 4.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 EOO03406.1 - 0.013 15.9 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain Glyco_hydro_67M PF07488.12 EOO03408.1 - 8.9e-146 485.1 0.0 1.7e-145 484.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 EOO03408.1 - 1.1e-86 290.0 0.6 1.6e-86 289.5 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 EOO03408.1 - 8.6e-30 103.5 0.0 1.4e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 EOO03408.1 - 0.0046 17.7 0.1 0.01 16.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Dabb PF07876.12 EOO03409.1 - 1e-23 83.8 0.0 1.1e-23 83.6 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Seryl_tRNA_N PF02403.22 EOO03410.1 - 0.028 14.7 4.2 0.043 14.0 4.2 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3510 PF12022.8 EOO03410.1 - 0.31 11.4 3.2 0.37 11.2 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) adh_short PF00106.25 EOO03411.1 - 2e-19 69.9 0.0 6.3e-17 61.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03411.1 - 1.3e-10 41.3 0.0 3.3e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO03411.1 - 2.1e-05 24.5 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO03411.1 - 4.6e-05 23.0 0.0 5.9e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3431 PF11913.8 EOO03412.1 - 5.8e-62 209.3 0.1 7.2e-62 209.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Epimerase PF01370.21 EOO03413.1 - 4.9e-25 88.4 0.0 6.1e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO03413.1 - 6.8e-17 61.9 0.3 3.5e-15 56.2 0.3 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EOO03413.1 - 1.5e-11 44.0 0.6 1.9e-07 30.5 0.0 3.0 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EOO03413.1 - 8.8e-11 41.4 0.0 1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EOO03413.1 - 3.9e-09 36.0 0.3 2.5e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 EOO03413.1 - 6.1e-06 25.4 0.0 4.8e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EOO03413.1 - 0.0014 18.6 1.0 0.1 12.5 0.0 2.4 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 EOO03413.1 - 0.2 11.1 0.1 9.6 5.6 0.0 2.2 1 1 1 2 2 2 0 short chain dehydrogenase MARVEL PF01284.23 EOO03414.1 - 3.2e-14 53.2 12.5 3.8e-14 52.9 12.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Wzy_C_2 PF11846.8 EOO03414.1 - 0.0042 17.0 0.3 0.09 12.7 0.2 2.1 2 0 0 2 2 2 1 Virulence factor membrane-bound polymerase, C-terminal DUF4381 PF14316.6 EOO03414.1 - 0.35 11.1 4.3 0.86 9.8 0.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) MARVEL PF01284.23 EOO03416.1 - 7.3e-05 22.8 19.7 0.0001 22.4 19.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4293 PF14126.6 EOO03416.1 - 0.0084 16.4 10.0 0.031 14.6 8.0 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF4293) SelK_SelG PF10961.8 EOO03416.1 - 0.69 10.6 0.0 0.69 10.6 0.0 2.1 3 1 0 3 3 3 0 Selenoprotein SelK_SelG DUF1980 PF09323.10 EOO03416.1 - 4.1 7.3 8.6 4.3 7.2 2.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Flavoprotein PF02441.19 EOO03417.1 - 1.3e-19 70.5 0.0 2.2e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein ABC_tran PF00005.27 EOO03418.1 - 3.4e-36 124.8 3.3 1.1e-22 81.0 0.0 3.5 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EOO03418.1 - 7.4e-20 70.8 9.6 7.4e-20 70.8 9.6 4.8 4 1 1 5 5 4 1 ABC transporter AAA_21 PF13304.6 EOO03418.1 - 7.9e-12 45.6 4.7 0.00029 20.7 0.0 3.8 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EOO03418.1 - 1.4e-09 37.7 2.1 0.0012 18.3 0.0 3.6 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EOO03418.1 - 8.9e-05 22.3 0.2 0.00061 19.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EOO03418.1 - 0.0047 17.2 0.0 0.017 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EOO03418.1 - 0.027 15.0 0.0 0.027 15.0 0.0 3.9 3 1 0 3 3 2 0 AAA domain AAA_18 PF13238.6 EOO03418.1 - 0.028 15.0 0.0 0.2 12.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EOO03418.1 - 0.053 13.4 0.4 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 EOO03418.1 - 0.097 13.1 0.0 0.36 11.3 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EOO03418.1 - 0.1 12.7 0.2 0.49 10.5 0.2 2.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase Halo_GVPC PF05465.13 EOO03418.1 - 0.1 12.8 1.5 1.2 9.4 0.2 2.6 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF2407_C PF13373.6 EOO03418.1 - 0.11 12.7 0.1 0.36 11.0 0.1 2.0 1 0 0 1 1 1 0 DUF2407 C-terminal domain AAA_24 PF13479.6 EOO03418.1 - 0.11 12.2 1.4 1 9.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EOO03418.1 - 0.11 12.4 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain SbcCD_C PF13558.6 EOO03418.1 - 0.11 12.7 0.7 13 6.1 0.2 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 EOO03418.1 - 0.17 11.5 0.0 0.17 11.5 0.0 4.3 4 1 0 4 4 4 0 AAA ATPase domain Tubulin PF00091.25 EOO03419.1 - 1.7e-68 230.7 0.0 4.4e-68 229.4 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EOO03419.1 - 5.4e-43 146.1 0.1 8.3e-43 145.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EOO03419.1 - 2.1e-05 24.8 0.0 5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EOO03419.1 - 0.0013 18.0 0.0 0.024 13.8 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 EOO03419.1 - 0.0033 17.1 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain bZIP_1 PF00170.21 EOO03420.1 - 1.2e-06 28.6 4.5 1.9e-06 27.8 4.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EOO03420.1 - 4.2e-06 26.7 6.1 4.2e-06 26.7 6.1 1.6 2 0 0 2 2 2 1 Basic region leucine zipper TTKRSYEDQ PF10212.9 EOO03420.1 - 0.0074 15.3 0.2 0.01 14.9 0.2 1.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein Fes1 PF08609.10 EOO03420.1 - 0.0083 17.0 0.8 0.024 15.5 0.8 1.8 1 1 0 1 1 1 1 Nucleotide exchange factor Fes1 DUF908 PF06012.12 EOO03420.1 - 0.84 9.0 4.3 0.94 8.8 4.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SRP40_C PF05022.12 EOO03421.1 - 2.9e-25 88.9 0.5 1.1e-24 87.0 0.5 2.1 1 0 0 1 1 1 1 SRP40, C-terminal domain Methyltransf_25 PF13649.6 EOO03422.1 - 6.7e-07 29.9 0.0 1.4e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO03422.1 - 8e-05 23.2 0.0 0.0002 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO03422.1 - 0.00048 20.8 0.0 0.00086 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FF PF01846.19 EOO03422.1 - 0.052 13.7 2.6 0.79 9.9 0.0 3.1 3 0 0 3 3 3 0 FF domain NnrU PF07298.11 EOO03423.1 - 0.13 11.8 5.7 0.46 9.9 0.4 2.1 2 0 0 2 2 2 0 NnrU protein Peptidase_A24 PF01478.18 EOO03423.1 - 2.8 8.4 10.0 4.7 7.7 1.4 2.2 2 0 0 2 2 2 0 Type IV leader peptidase family Complex1_51K PF01512.17 EOO03424.1 - 7.1e-48 162.3 0.0 1.3e-47 161.5 0.0 1.5 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EOO03424.1 - 3e-29 100.9 1.1 5.9e-29 100.0 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region PEX11 PF05648.14 EOO03424.1 - 2.6e-18 66.3 0.0 1.2e-17 64.2 0.0 2.0 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) SLBB PF10531.9 EOO03424.1 - 1.2e-07 31.4 0.0 3.1e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 SLBB domain MRP-L46 PF11788.8 EOO03426.1 - 0.1 13.3 0.0 0.19 12.5 0.0 1.4 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 adh_short PF00106.25 EOO03427.1 - 2.3e-17 63.1 0.1 2.7e-13 49.8 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03427.1 - 2.1e-11 43.8 0.0 3.3e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO03427.1 - 2.6e-05 24.2 0.0 3.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EOO03427.1 - 0.078 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pox_E6 PF04656.12 EOO03427.1 - 0.13 10.7 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Pox virus E6 protein VWA PF00092.28 EOO03428.1 - 0.001 19.4 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EOO03428.1 - 0.056 12.8 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein DIOX_N PF14226.6 EOO03429.1 - 2.5e-27 95.9 0.0 4.1e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EOO03429.1 - 3.5e-14 53.1 0.0 7.2e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.25 EOO03430.1 - 1.1e-21 77.2 0.4 1.3e-21 76.9 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03430.1 - 1.1e-13 51.3 0.0 1.5e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO03430.1 - 1.8e-09 37.8 0.2 2.5e-09 37.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO03430.1 - 0.0022 17.5 0.6 0.0041 16.6 0.6 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EOO03430.1 - 0.0063 15.7 0.5 0.01 15.0 0.5 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 EOO03430.1 - 0.012 14.9 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4156 PF13698.6 EOO03430.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) vATP-synt_AC39 PF01992.16 EOO03431.1 - 1e-110 370.4 0.0 1.2e-110 370.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.18 EOO03432.1 - 8.8e-80 267.5 0.9 1.3e-79 266.9 0.1 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EOO03432.1 - 3.8e-17 62.4 0.4 3.8e-17 62.4 0.4 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain ubiquitin PF00240.23 EOO03433.1 - 0.004 16.9 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF1923 PF09083.10 EOO03433.1 - 0.38 10.5 1.2 0.54 10.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1923) Transp_cyt_pur PF02133.15 EOO03434.1 - 2e-95 320.1 40.7 2.3e-95 320.0 40.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ribosomal_S2 PF00318.20 EOO03435.1 - 3.5e-26 91.8 0.3 6.5e-15 55.0 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EOO03435.1 - 0.0003 22.1 13.5 0.00055 21.2 13.5 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S15 PF00312.22 EOO03436.1 - 1e-23 83.3 0.9 2.6e-23 82.0 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 Med14 PF08638.11 EOO03436.1 - 0.048 13.1 1.9 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Mediator complex subunit MED14 CNOT11 PF10155.9 EOO03436.1 - 0.24 11.5 0.6 3.9 7.7 0.1 2.1 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 AMPK1_CBM PF16561.5 EOO03437.1 - 7.8e-18 64.5 1.4 4.4e-17 62.1 1.4 2.0 1 1 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 EOO03437.1 - 0.0048 17.5 0.3 0.0091 16.6 0.3 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CBM_48 PF02922.18 EOO03437.1 - 0.028 14.8 0.1 0.054 13.9 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) RasGAP PF00616.19 EOO03438.1 - 5.3e-10 39.4 0.0 0.00012 21.8 0.0 2.8 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EOO03438.1 - 1.4e-06 28.5 0.0 4e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 C2 domain Asn_synthase PF00733.21 EOO03439.1 - 1.1e-93 314.7 0.1 1.2e-53 183.1 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EOO03439.1 - 3.9e-32 110.7 0.0 8e-32 109.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EOO03439.1 - 2.2e-18 66.8 0.1 6.9e-18 65.1 0.0 1.9 2 1 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EOO03439.1 - 1.4e-05 24.7 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EOO03439.1 - 0.001 18.2 0.1 0.0036 16.5 0.1 1.8 1 1 0 1 1 1 1 NAD synthase Porin_3 PF01459.22 EOO03440.1 - 6.1e-69 232.5 8.5 1.3e-57 195.3 2.8 2.0 2 0 0 2 2 2 2 Eukaryotic porin SPAN PF02510.14 EOO03441.1 - 0.039 13.1 0.1 0.047 12.9 0.1 1.1 1 0 0 1 1 1 0 Surface presentation of antigens protein FXMRP1_C_core PF12235.8 EOO03441.1 - 0.1 13.3 0.3 0.12 13.0 0.3 1.2 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal FoP_duplication PF13865.6 EOO03441.1 - 0.46 11.1 6.6 0.72 10.5 6.6 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 CDPS PF16715.5 EOO03442.1 - 0.031 13.9 0.1 0.059 13.0 0.1 1.4 1 0 0 1 1 1 0 Cyclodipeptide synthase COQ7 PF03232.13 EOO03443.1 - 2.5e-70 235.7 0.3 3e-70 235.5 0.3 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 EOO03443.1 - 0.014 15.8 0.0 0.03 14.7 0.0 1.5 1 1 0 1 1 1 0 Rubrerythrin DUF724 PF05266.14 EOO03443.1 - 0.24 11.2 0.4 0.37 10.6 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF202 PF02656.15 EOO03444.1 - 1.1e-15 57.8 4.3 2.5e-15 56.7 2.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) FTHFS PF01268.19 EOO03445.1 - 1.3e-255 848.9 0.0 1.7e-255 848.5 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EOO03445.1 - 4.8e-67 224.2 0.9 4.8e-67 224.2 0.9 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EOO03445.1 - 6.8e-38 129.5 0.1 1.4e-37 128.5 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.27 EOO03445.1 - 0.097 12.2 0.4 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Helicase_C_4 PF13871.6 EOO03445.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue Ino80_Iec3 PF14612.6 EOO03446.1 - 6.8e-48 164.4 1.4 1.4e-23 84.8 4.5 2.2 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling Pex19 PF04614.12 EOO03447.1 - 3.5e-66 223.5 12.7 5.5e-66 222.8 12.7 1.3 1 0 0 1 1 1 1 Pex19 protein family Npun_R1517 PF18068.1 EOO03447.1 - 0.082 13.2 0.5 4.9 7.5 0.1 2.5 2 0 0 2 2 2 0 Npun R1517 ApbA_C PF08546.11 EOO03447.1 - 0.11 12.7 0.6 0.36 11.1 0.6 2.0 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal KIX_2 PF16987.5 EOO03447.1 - 0.16 12.0 1.8 5.9 7.0 0.1 2.8 2 0 0 2 2 2 0 KIX domain FliE PF02049.18 EOO03447.1 - 3.3 7.9 11.7 4 7.7 5.0 3.1 2 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE Gln-synt_C PF00120.24 EOO03448.1 - 7.9e-77 258.6 0.0 1.2e-76 258.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 EOO03448.1 - 3.8e-16 59.7 0.0 9e-16 58.5 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase Nop16 PF09420.10 EOO03449.1 - 0.053 13.5 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 NmrA PF05368.13 EOO03450.1 - 2.6e-31 109.0 0.2 4.7e-31 108.1 0.2 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO03450.1 - 3.2e-09 36.9 0.0 4.6e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EOO03450.1 - 9.7e-07 28.5 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO03450.1 - 0.0046 16.4 0.0 0.011 15.2 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short_C2 PF13561.6 EOO03450.1 - 0.0075 15.9 0.2 0.011 15.3 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO03450.1 - 0.02 14.3 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 EOO03450.1 - 0.063 12.6 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EOO03450.1 - 0.095 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain THF_DHG_CYH_C PF02882.19 EOO03450.1 - 0.1 11.9 0.3 0.21 10.9 0.3 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RTA1 PF04479.13 EOO03451.1 - 1.4e-30 106.4 8.9 1.4e-30 106.4 8.9 1.3 2 0 0 2 2 2 1 RTA1 like protein Peptidase_M19 PF01244.21 EOO03452.1 - 2.9e-106 355.3 0.0 3.7e-106 354.9 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) CFEM PF05730.11 EOO03453.1 - 0.39 10.8 12.7 0.8 9.8 12.0 2.0 1 1 0 1 1 1 0 CFEM domain RIFIN PF02009.16 EOO03453.1 - 0.94 9.3 6.3 0.99 9.2 6.3 1.0 1 0 0 1 1 1 0 Rifin p450 PF00067.22 EOO03454.1 - 3.3e-42 144.8 0.0 3.9e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pur_DNA_glyco PF02245.16 EOO03454.1 - 0.041 13.3 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Methylpurine-DNA glycosylase (MPG) Peptidase_C2 PF00648.21 EOO03455.1 - 2.2e-62 210.8 0.3 5.1e-61 206.3 0.3 2.4 1 1 0 1 1 1 1 Calpain family cysteine protease Ribosomal_S18 PF01084.20 EOO03456.1 - 1.7e-12 47.3 0.1 5.7e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S18 MWFE PF15879.5 EOO03458.1 - 0.24 11.6 1.4 0.41 10.9 1.4 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit Ribosomal_L24e PF01246.20 EOO03459.1 - 6e-31 106.5 6.2 1.3e-30 105.4 6.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e DUF5078 PF16877.5 EOO03459.1 - 0.015 15.7 0.1 0.029 14.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5078) FACT-Spt16_Nlob PF14826.6 EOO03461.1 - 2.4e-56 190.0 0.7 8.4e-56 188.2 0.7 2.1 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 EOO03461.1 - 9.7e-55 184.9 0.1 9.7e-55 184.9 0.1 3.3 4 0 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 EOO03461.1 - 5.9e-28 98.0 0.0 1.3e-27 96.9 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EOO03461.1 - 7e-16 58.4 1.8 1.2e-15 57.7 0.2 2.3 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Alba PF01918.21 EOO03462.1 - 2.5e-07 30.4 0.0 4.4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Alba Ureidogly_lyase PF04115.12 EOO03463.1 - 1.2e-31 110.0 0.0 1.5e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate lyase ALAD PF00490.21 EOO03464.1 - 4.1e-120 400.7 0.0 4.6e-120 400.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Abhydrolase_3 PF07859.13 EOO03465.1 - 6.1e-58 196.2 0.0 8e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EOO03465.1 - 1.1e-07 31.2 0.0 3.1e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EOO03465.1 - 0.00029 20.4 0.0 0.8 9.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 EOO03465.1 - 0.044 13.3 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Eno-Rase_NADH_b PF12242.8 EOO03465.1 - 0.066 13.0 0.1 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_76 PF03663.14 EOO03466.1 - 3.7e-155 517.0 10.4 4.3e-155 516.7 10.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EOO03466.1 - 0.014 14.5 8.9 0.77 8.8 0.1 3.2 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Tfb5 PF06331.12 EOO03467.1 - 1.2e-26 92.4 0.4 1.3e-26 92.3 0.4 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 CsoS2_M PF12288.8 EOO03468.1 - 0.11 11.9 0.6 0.17 11.3 0.6 1.2 1 0 0 1 1 1 0 Carboxysome shell peptide mid-region bZIP_1 PF00170.21 EOO03469.1 - 0.013 15.5 17.1 0.14 12.3 17.1 2.1 1 1 0 1 1 1 0 bZIP transcription factor ASD2 PF08687.11 EOO03469.1 - 0.071 12.7 7.0 0.11 12.0 7.0 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 DUF3560 PF12083.8 EOO03469.1 - 0.1 12.7 5.6 0.1 12.8 4.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3560) YabA PF06156.13 EOO03469.1 - 0.11 13.2 1.3 0.19 12.4 1.3 1.4 1 0 0 1 1 1 0 Initiation control protein YabA SPX PF03105.19 EOO03469.1 - 0.21 11.5 14.9 0.32 10.9 14.9 1.3 1 1 0 1 1 1 0 SPX domain PDE4_UCR PF18100.1 EOO03469.1 - 0.29 11.8 3.3 0.51 11.0 3.3 1.4 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) IncFII_repA PF02387.15 EOO03469.1 - 0.31 10.3 3.5 0.4 9.9 3.5 1.1 1 0 0 1 1 1 0 IncFII RepA protein family ATG16 PF08614.11 EOO03469.1 - 0.41 10.8 15.8 0.62 10.2 15.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) HALZ PF02183.18 EOO03469.1 - 1.1 9.6 7.7 1.7 9.0 0.6 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Macoilin PF09726.9 EOO03469.1 - 3 6.3 11.1 4.5 5.7 11.1 1.2 1 0 0 1 1 1 0 Macoilin family MerR_2 PF13591.6 EOO03469.1 - 3.1 7.7 5.4 1.5 8.7 0.6 2.0 1 1 0 2 2 2 0 MerR HTH family regulatory protein DUF4407 PF14362.6 EOO03469.1 - 5.3 6.3 6.4 6.8 5.9 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4337 PF14235.6 EOO03469.1 - 6.5 6.8 6.6 10 6.2 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Wbp11 PF09429.10 EOO03469.1 - 7.1 7.1 14.3 15 6.0 14.3 1.6 1 1 0 1 1 1 0 WW domain binding protein 11 DUF1003 PF06210.11 EOO03469.1 - 7.4 6.7 5.6 7.5 6.7 4.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) bZIP_2 PF07716.15 EOO03469.1 - 7.9 6.6 18.7 8.4 6.6 3.0 2.3 1 1 1 2 2 2 0 Basic region leucine zipper FTA4 PF13093.6 EOO03471.1 - 5.7e-72 241.8 0.0 6.9e-72 241.6 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF2462 PF09495.10 EOO03474.1 - 1.5e-19 70.5 16.0 1.5e-19 70.5 16.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Peptidase_S30 PF01577.16 EOO03474.1 - 0.0013 18.4 3.9 0.0015 18.2 3.9 1.0 1 0 0 1 1 1 1 Potyvirus P1 protease DnaJ PF00226.31 EOO03475.1 - 3.2e-21 75.2 2.8 4.9e-21 74.6 2.8 1.3 1 0 0 1 1 1 1 DnaJ domain Cu-oxidase_2 PF07731.14 EOO03476.1 - 3.2e-44 150.0 12.9 6.7e-41 139.2 0.4 4.1 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EOO03476.1 - 5.4e-43 145.8 6.3 1.9e-41 140.8 1.5 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EOO03476.1 - 9.2e-33 113.6 0.1 2.9e-32 112.0 0.1 1.9 1 0 0 1 1 1 1 Multicopper oxidase SH3_9 PF14604.6 EOO03477.1 - 2.1e-13 49.9 0.0 4.7e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 EOO03477.1 - 2.2e-12 46.9 0.0 4.4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 EOO03477.1 - 2.3e-11 43.1 0.0 4.9e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 EOO03477.1 - 1.2e-09 38.6 0.0 7.4e-09 36.1 0.0 2.2 1 1 0 1 1 1 1 PH domain SH3_2 PF07653.17 EOO03477.1 - 0.0021 17.7 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 EOO03477.1 - 0.0039 17.6 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Pox_I6 PF04595.13 EOO03477.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus I6-like family PH_8 PF15409.6 EOO03477.1 - 0.16 12.3 0.0 0.98 9.7 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Plus-3 PF03126.18 EOO03478.1 - 4.9e-31 107.5 0.2 1.7e-30 105.8 0.0 2.0 2 0 0 2 2 2 1 Plus-3 domain UPF0160 PF03690.13 EOO03479.1 - 2.1e-133 444.8 0.0 2.4e-133 444.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) JAB PF01398.21 EOO03480.1 - 9.8e-19 67.5 0.0 1.7e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EOO03480.1 - 7e-17 61.9 0.7 1.2e-16 61.1 0.3 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Y_phosphatase3 PF13350.6 EOO03481.1 - 1.7e-47 162.4 0.0 2.1e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Methyltransf_23 PF13489.6 EOO03482.1 - 1.3e-16 60.9 0.0 2.3e-16 60.1 0.0 1.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO03482.1 - 1.7e-10 41.5 0.0 3.7e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO03482.1 - 1e-08 35.1 0.0 1.1e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO03482.1 - 6.4e-07 30.0 0.0 1.7e-06 28.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO03482.1 - 1.1e-05 26.0 0.0 2.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EOO03482.1 - 0.0048 16.4 0.0 0.0083 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 EOO03482.1 - 0.0062 15.9 0.0 0.022 14.1 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 EOO03482.1 - 0.0082 15.9 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) DUF5127 PF17168.4 EOO03483.1 - 6.9e-78 261.5 13.2 1e-77 261.0 13.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EOO03483.1 - 5e-74 247.7 0.6 4.5e-73 244.6 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EOO03483.1 - 2.2e-64 216.9 1.9 4.8e-64 215.8 0.3 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EOO03483.1 - 6.3e-07 28.8 0.0 2.2e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) Endosulfine PF04667.17 EOO03484.1 - 1.1e-27 95.9 0.0 1.7e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF5349 PF17298.2 EOO03484.1 - 0.089 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) SNF2_N PF00176.23 EOO03485.1 - 2.2e-73 247.0 0.0 4.6e-73 245.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EOO03485.1 - 3.7e-43 146.2 2.5 3.7e-43 146.2 2.5 2.3 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 EOO03485.1 - 4.9e-38 130.3 8.0 4.9e-38 130.3 8.0 3.6 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 EOO03485.1 - 1.8e-18 66.9 0.0 7.3e-18 64.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO03485.1 - 2.1e-09 37.6 3.3 2.3e-09 37.5 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 EOO03485.1 - 3.6e-05 23.9 0.1 0.16 12.2 0.0 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain HDA2-3 PF11496.8 EOO03485.1 - 5.5e-05 22.5 0.0 0.00023 20.4 0.0 2.1 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF1086 PF06461.11 EOO03485.1 - 0.0011 18.9 0.6 0.0026 17.6 0.6 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) DEAD PF00270.29 EOO03485.1 - 0.0024 17.6 0.0 0.0065 16.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3847 PF12958.7 EOO03485.1 - 0.019 15.1 1.3 0.1 12.7 1.3 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) DEAD_2 PF06733.15 EOO03485.1 - 0.039 13.6 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.6 EOO03485.1 - 0.1 12.6 0.0 0.45 10.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain Ku_C PF03730.14 EOO03485.1 - 0.95 10.2 4.9 0.65 10.7 0.1 3.1 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm zf-C2H2 PF00096.26 EOO03486.1 - 0.023 15.2 0.3 0.023 15.2 0.3 4.1 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EOO03486.1 - 0.046 13.9 1.9 0.15 12.2 1.4 1.9 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 EOO03486.1 - 0.67 11.0 0.3 0.67 11.0 0.3 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger Methyltransf_23 PF13489.6 EOO03488.1 - 1.7e-13 50.8 0.0 2.3e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO03488.1 - 1.4e-12 48.1 0.0 2.1e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO03488.1 - 4.1e-11 43.4 0.0 6e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO03488.1 - 2.3e-10 41.1 0.0 3.3e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO03488.1 - 2.7e-08 33.8 0.0 3.6e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EOO03488.1 - 0.0019 17.2 0.0 0.0024 16.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 EOO03488.1 - 0.051 12.9 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CheR PF01739.18 EOO03488.1 - 0.069 12.6 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain NOD2_WH PF17779.1 EOO03488.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 NOD2 winged helix domain DOT1 PF08123.13 EOO03488.1 - 0.18 11.3 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 Glyco_hydro_43 PF04616.14 EOO03489.1 - 1.3e-19 70.6 4.3 1.3e-19 70.6 4.3 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Tubulin PF00091.25 EOO03490.1 - 6.4e-68 228.8 0.1 9.4e-68 228.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EOO03490.1 - 1.4e-45 154.6 0.2 4.2e-45 153.0 0.1 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EOO03490.1 - 4.4e-07 30.2 0.0 9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EOO03490.1 - 0.071 12.8 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 Tubulin domain Tctex-1 PF03645.13 EOO03491.1 - 1.7e-38 131.0 0.0 1.9e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family NAD_binding_6 PF08030.12 EOO03492.1 - 3.2e-19 69.6 0.0 6.6e-19 68.6 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EOO03492.1 - 1.6e-15 57.3 10.1 1.6e-15 57.3 10.1 3.2 2 1 1 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EOO03492.1 - 1.1e-09 38.4 0.0 2.4e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EOO03492.1 - 0.0037 17.9 0.0 0.13 12.9 0.0 2.5 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Phage_holin_2_4 PF16082.5 EOO03492.1 - 0.55 10.0 2.7 0.45 10.3 0.2 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Patatin PF01734.22 EOO03493.1 - 9.8e-10 38.9 0.1 3.2e-09 37.3 0.1 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase tRNA-synt_2b PF00587.25 EOO03494.1 - 9.6e-34 116.9 0.0 1.6e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EOO03494.1 - 1.3e-18 67.2 8.1 2.7e-18 66.2 8.1 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain CorA PF01544.18 EOO03494.1 - 0.47 9.7 1.6 0.88 8.8 1.6 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Not3 PF04065.15 EOO03495.1 - 5.4e-90 300.9 19.7 9.2e-90 300.1 19.7 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EOO03495.1 - 8.3e-43 145.6 12.1 1.8e-42 144.5 12.1 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family ABC_tran_CTD PF16326.5 EOO03495.1 - 0.0014 18.9 5.0 0.0014 18.9 5.0 3.3 2 1 0 2 2 2 1 ABC transporter C-terminal domain Cep57_MT_bd PF06657.13 EOO03495.1 - 0.016 15.7 8.6 0.82 10.2 0.4 2.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1192 PF06698.11 EOO03495.1 - 0.021 14.9 1.5 0.021 14.9 1.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) DUF2373 PF10180.9 EOO03495.1 - 0.028 14.3 3.3 0.061 13.2 3.3 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Syntaxin_2 PF14523.6 EOO03495.1 - 0.036 14.4 0.9 0.036 14.4 0.9 2.7 3 0 0 3 3 3 0 Syntaxin-like protein Med10 PF09748.9 EOO03495.1 - 0.11 12.5 0.9 0.28 11.1 0.9 1.7 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex LPP PF04728.13 EOO03495.1 - 0.31 11.5 2.7 0.86 10.0 0.4 2.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper HR1 PF02185.16 EOO03495.1 - 0.41 10.8 6.9 0.33 11.1 0.7 2.7 2 0 0 2 2 2 0 Hr1 repeat CorA PF01544.18 EOO03495.1 - 0.76 9.0 3.1 0.62 9.3 0.9 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4140 PF13600.6 EOO03495.1 - 1.4 9.4 5.6 6.8 7.2 0.7 3.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CENP-Q PF13094.6 EOO03495.1 - 5.4 7.2 16.3 5.2 7.2 3.0 2.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CTP_transf_like PF01467.26 EOO03496.1 - 9e-23 81.0 0.0 1.3e-19 70.8 0.0 3.1 2 1 1 3 3 3 2 Cytidylyltransferase-like MFS_1 PF07690.16 EOO03497.1 - 5.6e-12 45.3 15.2 1.6e-11 43.7 15.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily SUZ PF12752.7 EOO03498.1 - 8.1e-16 58.5 1.4 8.1e-16 58.5 1.4 3.0 2 0 0 2 2 2 1 SUZ domain R3H PF01424.22 EOO03498.1 - 5.3e-09 35.9 0.1 9.8e-09 35.1 0.1 1.4 1 0 0 1 1 1 1 R3H domain Glyco_transf_8 PF01501.20 EOO03498.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 8 ABC1 PF03109.16 EOO03499.1 - 3.6e-33 114.2 0.0 5.8e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 ABC1 family PRELI PF04707.14 EOO03500.1 - 2e-42 144.7 0.0 2.5e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family MCM PF00493.23 EOO03501.1 - 5e-101 336.5 0.0 5e-101 336.5 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EOO03501.1 - 1.1e-39 135.2 0.1 2.1e-39 134.3 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 EOO03501.1 - 7.4e-33 114.0 34.6 7.4e-33 114.0 34.6 1.9 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 EOO03501.1 - 4.5e-26 91.1 0.7 1.2e-25 89.8 0.7 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EOO03501.1 - 5.9e-15 55.7 0.1 1.5e-14 54.4 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EOO03501.1 - 8.2e-08 31.9 0.0 4e-06 26.3 0.0 2.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EOO03501.1 - 2.2e-06 27.7 0.0 5.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EOO03501.1 - 0.0013 18.6 0.0 0.014 15.2 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EOO03501.1 - 0.0028 17.4 0.2 0.02 14.6 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zn_ribbon_2 PF12674.7 EOO03501.1 - 0.14 12.8 0.9 0.4 11.4 0.9 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain FlgN PF05130.12 EOO03502.1 - 0.00037 21.0 0.7 0.00037 21.0 0.7 2.3 1 1 1 2 2 2 1 FlgN protein DUF4763 PF15960.5 EOO03502.1 - 0.0005 19.4 4.0 0.00069 19.0 3.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4763) DUF2353 PF09789.9 EOO03502.1 - 0.0014 18.1 4.3 0.0023 17.3 4.3 1.3 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Phage_lysis PF03245.13 EOO03502.1 - 0.0083 16.3 3.2 2 8.6 0.8 2.8 2 0 0 2 2 2 2 Bacteriophage Rz lysis protein SOGA PF11365.8 EOO03502.1 - 0.018 16.2 1.1 0.079 14.1 1.1 2.2 1 0 0 1 1 1 0 Protein SOGA Bacillus_HBL PF05791.11 EOO03502.1 - 0.025 14.4 1.3 0.11 12.3 0.2 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) SHE3 PF17078.5 EOO03502.1 - 0.026 14.3 3.6 0.048 13.4 3.6 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Golgin_A5 PF09787.9 EOO03502.1 - 0.031 13.7 5.9 0.057 12.9 5.9 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 LMBR1 PF04791.16 EOO03502.1 - 0.098 11.6 3.2 0.13 11.1 3.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2939 PF11159.8 EOO03502.1 - 0.18 12.3 1.6 0.66 10.4 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2939) Retrotrans_gag PF03732.17 EOO03502.1 - 0.3 11.4 5.0 0.7 10.2 4.3 2.0 1 1 0 1 1 1 0 Retrotransposon gag protein TMPIT PF07851.13 EOO03502.1 - 0.61 9.3 4.1 0.53 9.5 1.8 1.8 1 1 1 2 2 2 0 TMPIT-like protein CENP-Q PF13094.6 EOO03502.1 - 0.7 10.1 12.7 0.13 12.5 7.7 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TEX13 PF15186.6 EOO03502.1 - 1.2 8.9 8.1 4.4 7.0 0.6 3.0 2 1 2 4 4 4 0 Testis-expressed sequence 13 protein family APG6_N PF17675.1 EOO03502.1 - 2.3 8.7 12.9 0.14 12.7 6.6 2.2 2 1 1 3 3 2 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 EOO03502.1 - 2.3 8.3 11.5 1.3 9.1 7.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 EOO03502.1 - 4.2 8.3 11.7 3.1 8.8 7.0 2.8 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain FMN_bind_2 PF04299.12 EOO03503.1 - 4.5e-59 198.9 0.0 5.4e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain TLC PF03219.14 EOO03503.1 - 0.17 10.6 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 TLC ATP/ADP transporter DUF4611 PF15387.6 EOO03504.1 - 8.1 6.7 12.1 0.74 10.1 4.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Iso_dh PF00180.20 EOO03505.1 - 1.1e-73 248.4 0.0 1.3e-73 248.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ADH_N PF08240.12 EOO03506.1 - 1.7e-22 79.3 4.5 2.4e-22 78.9 4.5 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Peptidase_M24 PF00557.24 EOO03507.1 - 6.1e-42 143.7 0.1 7.8e-42 143.3 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3323 PF11796.8 EOO03507.1 - 0.017 15.0 0.2 0.03 14.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) RPN2_C PF18004.1 EOO03507.1 - 0.15 12.0 6.8 0.31 10.9 6.8 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CCDC106 PF15794.5 EOO03507.1 - 0.47 10.1 5.9 0.9 9.2 5.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 PGA2 PF07543.12 EOO03507.1 - 7.6 6.5 12.1 0.71 9.8 6.4 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 Coilin_N PF15862.5 EOO03507.1 - 8.4 6.2 7.8 22 4.8 7.8 1.6 1 0 0 1 1 1 0 Coilin N-terminus Cupin_5 PF06172.11 EOO03508.1 - 3.8e-47 160.0 0.0 4.6e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) zf-RING_5 PF14634.6 EOO03509.1 - 0.0024 17.8 6.5 0.0024 17.8 6.5 2.8 3 0 0 3 3 3 1 zinc-RING finger domain LETM1 PF07766.13 EOO03509.1 - 0.012 15.0 0.4 1.9 7.8 0.1 2.6 1 1 1 2 2 2 0 LETM1-like protein SNF2_N PF00176.23 EOO03509.1 - 0.023 13.4 0.0 0.048 12.4 0.0 1.5 1 0 0 1 1 1 0 SNF2 family N-terminal domain CNDH2_C PF16858.5 EOO03509.1 - 0.087 12.7 12.5 5.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SDA1 PF05285.12 EOO03509.1 - 0.38 10.1 15.6 0.71 9.2 15.6 1.4 1 0 0 1 1 1 0 SDA1 zf-C3HC4_2 PF13923.6 EOO03509.1 - 1.9 8.4 9.3 0.36 10.7 4.0 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CDC45 PF02724.14 EOO03509.1 - 2.7 6.2 10.2 19 3.4 10.3 2.1 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 EOO03509.1 - 6.5 4.8 16.7 11 4.1 16.7 1.2 1 0 0 1 1 1 0 Nop14-like family COPIIcoated_ERV PF07970.12 EOO03511.1 - 2.3e-36 125.7 0.0 3.7e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EOO03511.1 - 2e-25 89.0 0.0 3.3e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) WD40 PF00400.32 EOO03512.1 - 5.3e-25 87.2 2.8 1.4e-08 35.2 0.4 5.7 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO03512.1 - 3.1e-13 49.8 0.0 9.8e-05 22.6 0.0 4.4 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EOO03512.1 - 9.3e-05 21.6 0.3 0.028 13.5 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.11 EOO03512.1 - 0.0034 17.3 0.2 1.4 8.8 0.1 3.2 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EOO03512.1 - 0.015 14.0 0.0 0.028 13.1 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EOO03512.1 - 0.032 13.0 0.0 0.057 12.2 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like Gmad1 PF10647.9 EOO03512.1 - 0.052 13.3 0.7 0.28 10.9 0.7 1.9 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.6 EOO03512.1 - 0.061 12.9 0.1 0.38 10.3 0.1 2.1 1 1 0 1 1 1 0 PQQ-like domain WD40_like PF17005.5 EOO03512.1 - 0.088 12.1 0.0 0.52 9.6 0.0 2.1 2 2 0 2 2 2 0 WD40-like domain Glyco_hydro_31 PF01055.26 EOO03513.1 - 8.3e-156 519.6 2.3 1e-155 519.3 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EOO03513.1 - 3.3e-38 130.5 0.0 6e-38 129.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EOO03513.1 - 7.6e-15 55.0 1.4 4e-14 52.7 1.4 2.4 1 0 0 1 1 1 1 Galactose mutarotase-like SNF2_N PF00176.23 EOO03514.1 - 8.7e-12 44.4 0.1 1.5e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.17 EOO03514.1 - 4.7e-10 39.3 0.0 3.1e-07 30.0 0.0 2.9 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase PPR_2 PF13041.6 EOO03515.1 - 1e-13 51.2 0.0 2.6e-07 30.7 0.0 4.9 4 1 1 5 5 5 3 PPR repeat family PPR_1 PF12854.7 EOO03515.1 - 5.4e-08 32.4 0.0 0.011 15.5 0.0 3.6 3 0 0 3 3 3 3 PPR repeat PPR PF01535.20 EOO03515.1 - 5.7e-07 29.4 0.3 0.016 15.4 0.0 3.7 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 EOO03515.1 - 6.2e-07 29.4 0.0 9.3e-06 25.6 0.0 2.6 3 0 0 3 3 3 1 Pentatricopeptide repeat domain GSH-S_ATP PF02955.16 EOO03515.1 - 0.089 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Pro_isomerase PF00160.21 EOO03516.1 - 3.5e-49 167.1 0.2 5.4e-49 166.5 0.2 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EOO03516.1 - 4e-08 32.8 5.6 7.6e-05 22.5 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EOO03516.1 - 1.7e-06 27.6 4.5 0.0002 21.1 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EOO03516.1 - 0.0022 17.7 2.3 0.76 9.5 0.1 3.2 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 EOO03516.1 - 0.0024 18.0 1.5 0.0038 17.4 0.8 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EOO03516.1 - 0.003 17.8 4.2 0.015 15.6 2.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EOO03516.1 - 0.0065 16.6 0.1 0.022 14.9 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 EOO03516.1 - 0.042 14.5 0.1 0.042 14.5 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EOO03516.1 - 0.05 14.3 6.4 0.73 10.5 4.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EOO03516.1 - 0.065 14.1 4.1 0.25 12.3 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat GCS PF03074.16 EOO03517.1 - 4e-152 506.8 0.0 4.5e-152 506.7 0.0 1.0 1 0 0 1 1 1 1 Glutamate-cysteine ligase Sigma70_r4 PF04545.16 EOO03517.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 PPR_2 PF13041.6 EOO03518.1 - 0.019 15.1 0.7 2.1 8.6 0.0 3.3 2 1 1 3 3 3 0 PPR repeat family PPR PF01535.20 EOO03518.1 - 0.046 14.0 6.8 2.2 8.7 0.0 4.2 5 0 0 5 5 5 0 PPR repeat SLAC1 PF03595.17 EOO03519.1 - 1.1e-78 264.7 43.5 1.3e-78 264.6 43.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SPT_ssu-like PF11779.8 EOO03519.1 - 0.22 11.2 0.1 0.22 11.2 0.1 4.3 5 1 0 6 6 6 0 Small subunit of serine palmitoyltransferase-like Glyco_hydro_3_C PF01915.22 EOO03520.1 - 3.7e-64 216.5 0.0 5.7e-64 215.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EOO03520.1 - 2.3e-40 138.9 0.0 4e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EOO03520.1 - 1.1e-25 89.5 1.9 3.1e-25 88.1 1.9 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EOO03520.1 - 1.4e-16 60.6 0.2 3.1e-16 59.5 0.0 1.7 2 0 0 2 2 2 1 PA14 domain CARDB PF07705.11 EOO03520.1 - 0.021 15.1 0.2 0.056 13.7 0.2 1.7 1 0 0 1 1 1 0 CARDB FMN_bind PF04205.14 EOO03520.1 - 0.14 12.8 0.2 0.67 10.6 0.2 2.2 1 0 0 1 1 1 0 FMN-binding domain CTP_transf_like PF01467.26 EOO03521.1 - 4.8e-30 104.6 0.0 8.7e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Ion_trans PF00520.31 EOO03522.1 - 3.1e-08 33.2 2.2 3.9e-08 32.8 2.2 1.2 1 0 0 1 1 1 1 Ion transport protein bZIP_1 PF00170.21 EOO03522.1 - 0.0019 18.2 1.4 0.0037 17.3 1.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor CDH1_2_SANT_HL1 PF18375.1 EOO03522.1 - 0.0064 17.1 0.5 0.19 12.4 0.2 2.3 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 DivIC PF04977.15 EOO03522.1 - 0.015 15.1 0.3 0.029 14.1 0.3 1.5 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 EOO03522.1 - 0.032 14.3 3.5 0.087 12.9 3.5 1.7 2 0 0 2 2 2 0 Basic region leucine zipper APC_N_CC PF16689.5 EOO03522.1 - 0.07 13.2 0.7 0.13 12.4 0.7 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Ran_BP1 PF00638.18 EOO03524.1 - 7.2e-17 61.8 0.1 1.5e-15 57.5 0.1 2.1 1 1 0 1 1 1 1 RanBP1 domain UQ_con PF00179.26 EOO03525.1 - 7.4e-50 168.2 0.1 8.3e-50 168.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EOO03525.1 - 0.00013 21.7 0.0 0.00025 20.8 0.0 1.6 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EOO03525.1 - 0.011 16.0 1.0 0.037 14.3 1.0 1.8 1 1 0 1 1 1 0 RWD domain MFS_1 PF07690.16 EOO03527.1 - 4.4e-31 108.1 22.2 5.8e-31 107.7 22.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EOO03527.1 - 0.0026 16.1 5.8 0.079 11.2 1.0 3.3 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family WD40 PF00400.32 EOO03528.1 - 4.9e-14 52.5 14.0 0.00022 22.0 0.2 5.5 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO03528.1 - 7.5e-07 29.4 0.0 0.0016 18.7 0.0 4.8 1 1 5 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EOO03528.1 - 5.2e-06 26.0 0.0 9e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Nup160 PF11715.8 EOO03528.1 - 0.013 14.2 1.4 0.65 8.6 0.6 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Bacteriocin_IIi PF11758.8 EOO03528.1 - 0.049 13.5 0.1 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Aureocin-like type II bacteriocin DUF3694 PF12473.8 EOO03528.1 - 0.09 13.4 0.1 15 6.2 0.0 2.4 2 0 0 2 2 2 0 Kinesin protein DUF1996 PF09362.10 EOO03529.1 - 5.2e-72 242.6 10.2 7.6e-72 242.1 6.2 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF1996) PLDc PF00614.22 EOO03532.1 - 1.4e-16 59.9 0.6 8.2e-07 29.0 0.4 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EOO03532.1 - 1.9e-13 50.4 0.1 2.7e-07 30.5 0.0 3.1 3 1 0 3 3 3 2 PLD-like domain PX PF00787.24 EOO03532.1 - 1.3e-06 28.4 0.2 1.9e-05 24.6 0.2 2.6 1 1 0 1 1 1 1 PX domain SRP72 PF08492.12 EOO03532.1 - 0.059 13.8 5.1 0.15 12.5 1.2 2.9 2 0 0 2 2 2 0 SRP72 RNA-binding domain DUF4028 PF13220.6 EOO03532.1 - 0.068 12.9 0.2 16 5.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) MatE PF01554.18 EOO03533.1 - 1.2e-29 103.1 7.1 8.7e-28 97.0 0.9 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EOO03533.1 - 1.9e-06 28.0 7.4 1.9e-06 28.0 7.4 3.0 2 1 1 3 3 3 2 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 EOO03533.1 - 0.028 13.0 0.9 0.041 12.5 0.3 1.6 2 0 0 2 2 2 0 Lipid II flippase MurJ S4 PF01479.25 EOO03534.1 - 3e-13 49.3 0.0 5.6e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 EOO03534.1 - 7.5e-11 42.8 0.4 1.1e-10 42.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain UPF0302 PF08864.10 EOO03534.1 - 0.0092 16.0 0.1 0.021 14.9 0.1 1.5 1 0 0 1 1 1 1 UPF0302 domain Vesiculo_matrix PF06326.12 EOO03534.1 - 0.069 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Vesiculovirus matrix protein AA_permease PF00324.21 EOO03535.1 - 2.4e-94 316.6 37.8 3.3e-94 316.2 37.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EOO03535.1 - 1.4e-33 116.4 42.6 2.2e-33 115.8 42.6 1.2 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_6 PF12697.7 EOO03536.1 - 5.7e-15 56.5 0.0 8.7e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EOO03536.1 - 1.5e-10 41.2 0.2 4.3e-10 39.7 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EOO03536.1 - 1.1e-06 28.1 0.0 2.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EOO03536.1 - 0.0033 17.2 0.0 0.021 14.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EOO03536.1 - 0.021 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Thioesterase PF00975.20 EOO03536.1 - 0.038 14.1 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 EOO03536.1 - 0.11 12.3 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.12 EOO03536.1 - 0.11 12.1 0.2 0.48 10.0 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase UTP25 PF06862.12 EOO03537.1 - 1.2e-180 601.3 0.1 1.8e-180 600.8 0.1 1.2 1 1 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AIM5 PF17050.5 EOO03538.1 - 7.1e-25 87.6 1.9 2e-24 86.2 1.9 1.8 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 T7SS_ESX_EspC PF10824.8 EOO03538.1 - 7.8 7.0 18.4 3.2 8.3 13.4 2.5 1 1 1 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm GFO_IDH_MocA PF01408.22 EOO03539.1 - 7.4e-14 52.6 0.0 1.3e-13 51.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EOO03539.1 - 0.04 13.9 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain DUF5565 PF17720.1 EOO03539.1 - 0.12 11.2 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5565) YLP PF02757.17 EOO03539.1 - 1.1 9.4 4.2 0.41 10.7 0.2 2.3 2 0 0 2 2 2 0 YLP motif Pyridoxal_deC PF00282.19 EOO03540.1 - 1.1e-21 77.1 0.0 2.7e-21 75.7 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EOO03540.1 - 0.0016 17.8 0.0 0.0035 16.7 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EOO03540.1 - 0.021 14.0 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II adh_short PF00106.25 EOO03541.1 - 2e-15 56.8 0.1 3.3e-15 56.1 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03541.1 - 6e-12 45.6 0.0 1.2e-11 44.6 0.0 1.4 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO03541.1 - 0.0057 16.6 0.1 0.0067 16.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Ribosomal_L44 PF00935.19 EOO03542.1 - 5.9e-34 116.4 7.4 7.8e-34 116.0 7.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Fungal_trans_2 PF11951.8 EOO03543.1 - 8.6e-11 41.3 1.0 2.7e-10 39.6 0.1 2.1 2 1 1 3 3 3 1 Fungal specific transcription factor domain DSBA PF01323.20 EOO03544.1 - 8.3e-22 77.9 0.0 9.5e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain cwf18 PF08315.12 EOO03545.1 - 5.5e-44 150.1 8.7 5.5e-44 150.1 8.7 1.8 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor PGP_phosphatase PF09419.10 EOO03545.1 - 0.05 13.2 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase ECH_1 PF00378.20 EOO03546.1 - 7.5e-14 51.6 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EOO03546.1 - 1.8e-13 50.7 0.0 2.5e-13 50.2 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_C71 PF12386.8 EOO03546.1 - 0.023 14.4 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei TSKS PF15358.6 EOO03547.1 - 0.47 8.8 2.6 2.7 6.2 0.1 2.0 2 0 0 2 2 2 0 Testis-specific serine kinase substrate SPX PF03105.19 EOO03547.1 - 9 6.1 6.8 11 5.8 6.8 1.1 1 0 0 1 1 1 0 SPX domain GlnD_UR_UTase PF08335.11 EOO03548.1 - 0.024 14.7 0.5 0.051 13.7 0.5 1.5 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase DUF4355 PF14265.6 EOO03548.1 - 0.096 12.9 1.4 0.27 11.5 1.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) V-SNARE PF05008.15 EOO03548.1 - 0.15 12.5 3.7 1.3 9.5 2.4 2.4 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Spectrin PF00435.21 EOO03548.1 - 0.19 12.2 7.6 0.22 12.0 5.3 2.1 2 1 0 2 2 2 0 Spectrin repeat FAD_binding_3 PF01494.19 EOO03550.1 - 3.2e-20 72.7 0.0 8e-20 71.4 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EOO03550.1 - 3.4e-09 36.8 1.8 0.0003 20.5 0.0 2.4 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EOO03550.1 - 6e-06 25.7 0.1 0.1 11.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EOO03550.1 - 0.00032 21.2 0.1 0.082 13.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EOO03550.1 - 0.0013 17.6 0.6 0.009 14.8 0.6 2.0 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EOO03550.1 - 0.0017 17.5 0.1 0.14 11.2 0.2 2.1 1 1 1 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EOO03550.1 - 0.0034 16.5 0.0 0.13 11.3 0.0 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EOO03550.1 - 0.004 17.4 0.0 0.009 16.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EOO03550.1 - 0.0049 16.9 0.4 2.5 8.1 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EOO03550.1 - 0.0049 16.2 0.2 0.62 9.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EOO03550.1 - 0.017 14.2 0.0 0.63 9.0 0.0 2.6 3 0 0 3 3 3 0 Squalene epoxidase FAD_oxidored PF12831.7 EOO03550.1 - 0.072 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thiolase_N PF00108.23 EOO03551.1 - 2.2e-15 56.7 0.0 1.8e-14 53.7 0.0 2.4 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EOO03551.1 - 4.2e-11 42.6 1.0 1.3e-10 41.0 0.1 2.2 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EOO03551.1 - 2.6e-05 24.0 0.6 0.0015 18.4 0.1 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 EOO03551.1 - 0.0029 16.4 1.0 0.3 9.8 0.1 2.3 2 0 0 2 2 2 2 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 EOO03551.1 - 0.0052 16.4 0.2 0.012 15.2 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EOO03551.1 - 0.018 15.1 0.7 1.1 9.3 0.3 3.2 2 1 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain PseudoU_synth_1 PF01416.20 EOO03552.1 - 6.5e-36 123.1 0.0 6.2e-34 116.7 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase BCDHK_Adom3 PF10436.9 EOO03553.1 - 8.6e-76 253.3 0.0 1.2e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EOO03553.1 - 3.3e-10 40.5 0.0 1e-09 38.8 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EOO03553.1 - 0.059 13.2 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Epimerase PF01370.21 EOO03554.1 - 3.9e-16 59.3 0.0 7.1e-16 58.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EOO03554.1 - 5.9e-11 41.9 0.0 1.4e-10 40.7 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EOO03554.1 - 2.6e-07 30.1 0.0 3.4e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EOO03554.1 - 1.3e-05 24.7 0.0 3.9e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EOO03554.1 - 2.3e-05 24.4 0.7 6.6e-05 22.9 0.2 2.0 2 1 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 EOO03554.1 - 0.01 15.3 0.0 0.026 14.0 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase NmrA PF05368.13 EOO03554.1 - 0.02 14.5 0.0 0.05 13.2 0.0 1.7 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 EOO03554.1 - 0.068 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Thr_synth_N PF14821.6 EOO03555.1 - 6.3e-27 93.6 0.0 1.4e-26 92.5 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 EOO03555.1 - 2.6e-18 66.5 0.0 1.3e-17 64.2 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SAC3_GANP PF03399.16 EOO03555.1 - 0.06 12.7 0.0 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 SAC3/GANP family DFRP_C PF16543.5 EOO03556.1 - 3.8e-27 94.6 7.4 3.8e-27 94.6 7.4 3.6 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 EOO03556.1 - 2.1e-06 27.5 0.9 2.1e-06 27.5 0.9 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EOO03556.1 - 4.9e-06 27.2 5.1 4.9e-06 27.2 5.1 2.9 2 1 1 3 3 3 1 Torus domain zf_CCCH_4 PF18345.1 EOO03556.1 - 9.3e-05 22.4 6.6 9.3e-05 22.4 6.6 2.1 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 EOO03556.1 - 0.00011 21.9 4.2 0.0011 18.7 2.1 2.3 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EOO03556.1 - 0.036 14.3 0.5 0.096 12.9 0.5 1.8 1 0 0 1 1 1 0 Zinc-finger containing family Arabino_trans_C PF14896.6 EOO03556.1 - 0.52 9.3 5.7 2.4 7.1 1.6 2.3 1 1 1 2 2 2 0 EmbC C-terminal domain zf-CCCH_2 PF14608.6 EOO03556.1 - 1 10.0 10.5 0.27 11.8 6.6 1.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger eIF_4EBP PF05456.11 EOO03556.1 - 3.9 7.4 6.1 0.81 9.6 0.6 2.5 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) EF-hand_6 PF13405.6 EOO03557.1 - 4e-08 32.6 0.1 0.012 15.5 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EOO03557.1 - 6e-06 26.6 6.1 9.1e-05 22.8 0.9 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EOO03557.1 - 1.2e-05 24.5 0.2 0.0005 19.4 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EOO03557.1 - 6.6e-05 22.2 0.1 0.00026 20.3 0.0 2.0 2 0 0 2 2 2 1 EF hand Fungal_trans PF04082.18 EOO03558.1 - 1.7e-15 56.8 0.0 3.2e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EOO03558.1 - 2.8e-06 27.3 18.9 6.7e-06 26.1 18.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TetR_C_35 PF18556.1 EOO03558.1 - 0.12 12.5 0.3 0.27 11.4 0.3 1.5 1 0 0 1 1 1 0 Bacterial Tetracyclin repressor, C-terminal domain LOB PF03195.14 EOO03558.1 - 0.29 11.7 5.3 0.45 11.1 4.1 2.0 2 0 0 2 2 2 0 Lateral organ boundaries (LOB) domain DUF2407_C PF13373.6 EOO03559.1 - 1.7e-37 128.7 0.1 2.2e-37 128.3 0.1 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 EOO03559.1 - 3.7e-31 107.8 0.0 5.8e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EOO03559.1 - 0.16 11.8 0.0 0.37 10.6 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin family VCBS PF13517.6 EOO03560.1 - 1.5e-29 102.3 62.5 1.6e-10 41.4 7.2 10.5 6 3 4 10 10 10 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 EOO03560.1 - 2.3e-09 36.9 9.9 0.35 10.2 0.1 6.8 7 1 0 7 7 7 5 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_2 PF13472.6 EOO03560.1 - 3.7e-09 37.2 0.1 1.2e-08 35.5 0.1 1.9 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EOO03560.1 - 2e-08 34.4 0.1 4.2e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EOO03560.1 - 8.8e-05 22.7 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.23 EOO03560.1 - 0.0003 20.8 11.8 0.00074 19.6 2.6 8.4 8 0 0 8 8 8 5 FG-GAP repeat RRM_1 PF00076.22 EOO03561.1 - 6.4e-09 35.5 0.0 4.4e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EOO03561.1 - 0.00048 20.6 2.2 0.00048 20.6 2.2 2.9 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RNA12 PF10443.9 EOO03562.1 - 2.1e-171 570.5 3.8 2.8e-171 570.1 3.8 1.1 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.22 EOO03562.1 - 4.1e-05 23.3 0.0 0.00038 20.2 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 EOO03562.1 - 9.8e-05 22.4 0.5 0.00096 19.1 0.3 2.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF2487 PF10673.9 EOO03562.1 - 0.00025 21.1 0.1 0.00074 19.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2487) KLRAQ PF10205.9 EOO03562.1 - 0.29 11.4 2.7 0.35 11.1 0.4 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein MMU163 PF17119.5 EOO03563.1 - 3e-80 269.0 7.3 3.8e-58 196.6 1.7 2.2 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis SnoaL_2 PF12680.7 EOO03563.1 - 0.0021 18.7 0.0 0.013 16.2 0.0 2.1 1 1 0 1 1 1 1 SnoaL-like domain Tom5 PF10642.9 EOO03563.1 - 0.075 13.1 0.3 0.075 13.1 0.3 1.8 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Peptidase_M41 PF01434.18 EOO03564.1 - 1.3e-48 165.4 0.1 2.4e-48 164.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EOO03564.1 - 6.1e-43 146.4 0.0 1.6e-42 145.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) adh_short PF00106.25 EOO03564.1 - 7.8e-20 71.2 0.1 2.3e-19 69.6 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03564.1 - 1.7e-16 60.5 0.5 3.5e-16 59.5 0.1 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase AAA_lid_3 PF17862.1 EOO03564.1 - 8.9e-11 41.4 0.0 2.1e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain KR PF08659.10 EOO03564.1 - 1.2e-06 28.6 0.0 3e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 KR domain AAA_16 PF13191.6 EOO03564.1 - 1.4e-05 25.6 2.3 0.00051 20.5 1.6 3.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EOO03564.1 - 2.9e-05 24.1 0.0 8.9e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EOO03564.1 - 5.5e-05 22.5 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EOO03564.1 - 0.00036 20.8 0.2 0.015 15.5 0.2 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EOO03564.1 - 0.00066 19.5 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EOO03564.1 - 0.0031 17.7 0.0 0.018 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EOO03564.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EOO03564.1 - 0.021 14.2 0.3 0.05 13.0 0.3 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EOO03564.1 - 0.031 14.8 0.0 0.11 13.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 EOO03564.1 - 0.038 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 EOO03564.1 - 0.039 13.5 1.3 0.96 9.0 0.3 3.0 2 1 1 3 3 3 0 AAA domain AAA_28 PF13521.6 EOO03564.1 - 0.049 13.9 0.1 0.23 11.7 0.0 2.2 2 0 0 2 2 1 0 AAA domain zinc_ribbon_16 PF17034.5 EOO03564.1 - 0.095 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family AAA_14 PF13173.6 EOO03564.1 - 0.14 12.2 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EOO03564.1 - 0.14 11.3 0.0 0.31 10.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 EOO03564.1 - 0.16 12.0 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EOO03564.1 - 0.29 11.0 1.2 2.4 8.0 0.1 2.7 3 0 0 3 3 3 0 NACHT domain Zeta_toxin PF06414.12 EOO03564.1 - 2.6 7.3 6.8 0.49 9.6 0.4 2.9 3 1 1 4 4 4 0 Zeta toxin Pirin PF02678.16 EOO03565.1 - 5.1e-31 106.9 0.1 9.2e-31 106.0 0.1 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EOO03565.1 - 1.4e-27 96.0 0.0 1.1e-25 90.0 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EOO03565.1 - 1.4e-07 31.1 2.0 2.8e-05 23.8 0.8 2.7 2 1 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EOO03565.1 - 0.00061 19.4 1.2 1 9.1 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF861) Cupin_7 PF12973.7 EOO03565.1 - 0.061 13.2 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 ChrR Cupin-like domain DUF2183 PF09949.9 EOO03566.1 - 3.6e-23 81.8 0.1 7.2e-23 80.8 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Pribosyltran_N PF13793.6 EOO03567.1 - 6.6e-41 138.9 0.0 1.5e-40 137.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EOO03567.1 - 1.9e-40 138.9 3.4 1.5e-34 119.6 2.4 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EOO03567.1 - 1.2e-14 54.1 0.3 2.8e-14 52.9 0.3 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EOO03567.1 - 0.045 13.2 0.1 0.075 12.5 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase HSF_DNA-bind PF00447.17 EOO03569.1 - 1.4e-22 80.1 0.9 1.9e-22 79.7 0.9 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 EOO03569.1 - 0.066 13.7 0.1 0.11 13.0 0.1 1.4 1 0 0 1 1 1 0 Ets-domain Retinal PF15449.6 EOO03569.1 - 0.082 10.7 3.1 0.092 10.5 3.1 1.0 1 0 0 1 1 1 0 Retinal protein ZapB PF06005.12 EOO03570.1 - 0.00012 22.5 27.3 0.00053 20.4 3.5 4.0 2 1 2 4 4 4 2 Cell division protein ZapB PRKG1_interact PF15898.5 EOO03570.1 - 0.00012 22.9 7.3 0.00012 22.9 7.3 2.7 1 1 2 3 3 3 1 cGMP-dependent protein kinase interacting domain DUF2968 PF11180.8 EOO03570.1 - 0.00054 19.6 4.2 0.00054 19.6 4.2 3.0 2 1 1 3 3 2 1 Protein of unknown function (DUF2968) YabA PF06156.13 EOO03570.1 - 0.00055 20.5 14.7 0.026 15.2 0.9 3.6 1 1 3 4 4 4 3 Initiation control protein YabA GIT_CC PF16559.5 EOO03570.1 - 0.0011 18.7 6.9 0.083 12.8 3.0 3.1 2 1 1 3 3 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor TACC_C PF05010.14 EOO03570.1 - 0.0012 18.7 2.2 0.0012 18.7 2.2 2.3 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TPR_MLP1_2 PF07926.12 EOO03570.1 - 0.0021 18.1 7.6 0.0021 18.1 7.6 2.8 2 2 0 2 2 2 1 TPR/MLP1/MLP2-like protein JIP_LZII PF16471.5 EOO03570.1 - 0.0022 18.1 16.7 0.22 11.7 3.2 3.8 1 1 3 4 4 4 1 JNK-interacting protein leucine zipper II ADIP PF11559.8 EOO03570.1 - 0.0024 18.0 4.5 0.0024 18.0 4.5 3.2 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 EOO03570.1 - 0.0048 17.0 13.6 0.83 9.8 0.1 4.6 1 1 4 5 5 5 2 bZIP transcription factor Spc7 PF08317.11 EOO03570.1 - 0.0053 15.7 4.4 0.0053 15.7 4.4 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein GAS PF13851.6 EOO03570.1 - 0.0062 15.9 11.7 0.0062 15.9 11.7 2.3 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.11 EOO03570.1 - 0.0064 16.9 2.6 8.2 6.9 0.0 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Cnn_1N PF07989.11 EOO03570.1 - 0.007 16.5 14.1 0.067 13.3 1.8 3.4 2 2 2 4 4 3 3 Centrosomin N-terminal motif 1 Wtap PF17098.5 EOO03570.1 - 0.012 15.6 10.3 0.019 14.9 7.3 2.6 1 1 1 2 2 2 0 WTAP/Mum2p family TolA_bind_tri PF16331.5 EOO03570.1 - 0.013 15.6 22.3 0.1 12.7 4.8 3.3 1 1 2 3 3 3 0 TolA binding protein trimerisation TSC22 PF01166.18 EOO03570.1 - 0.016 15.5 11.6 0.31 11.4 0.3 4.3 3 1 1 4 4 4 0 TSC-22/dip/bun family Prominin PF05478.11 EOO03570.1 - 0.02 12.9 3.1 0.024 12.6 3.1 1.3 1 0 0 1 1 1 0 Prominin KASH_CCD PF14662.6 EOO03570.1 - 0.029 14.2 18.0 0.38 10.5 18.0 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Csm1_N PF18504.1 EOO03570.1 - 0.049 14.0 11.2 0.3 11.5 0.7 3.5 1 1 3 4 4 4 0 Csm1 N-terminal domain DUF1664 PF07889.12 EOO03570.1 - 0.051 13.6 4.0 1.5 8.8 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GP57 PF17594.2 EOO03570.1 - 0.068 12.9 1.5 0.16 11.7 0.0 2.3 3 0 0 3 3 2 0 Phage Tail fiber assembly helper gene product 57 CENP-H PF05837.12 EOO03570.1 - 0.071 13.5 18.9 0.78 10.2 8.1 3.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Bmp PF02608.14 EOO03570.1 - 0.074 12.0 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 ABC transporter substrate-binding protein PnrA-like Fungal_TACC PF12709.7 EOO03570.1 - 0.088 13.3 8.2 6 7.4 0.6 3.5 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins LPP PF04728.13 EOO03570.1 - 0.092 13.1 4.6 2.7 8.5 0.1 3.3 2 1 2 4 4 3 0 Lipoprotein leucine-zipper Baculo_PEP_C PF04513.12 EOO03570.1 - 0.14 12.2 3.9 0.61 10.1 3.8 2.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Jnk-SapK_ap_N PF09744.9 EOO03570.1 - 0.14 12.4 23.0 0.067 13.4 10.3 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DivIC PF04977.15 EOO03570.1 - 0.14 11.9 22.7 0.078 12.8 1.2 4.3 1 1 4 5 5 5 0 Septum formation initiator Seadorna_VP6 PF07407.11 EOO03570.1 - 0.15 11.0 3.9 0.26 10.2 0.8 2.0 1 1 1 2 2 2 0 Seadornavirus VP6 protein DUF4407 PF14362.6 EOO03570.1 - 0.19 11.0 16.9 0.4 10.0 16.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 EOO03570.1 - 0.23 11.7 2.3 1.5 9.2 0.2 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Herpes_BLRF2 PF05812.12 EOO03570.1 - 0.26 11.4 8.5 0.053 13.7 2.8 2.7 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein Seryl_tRNA_N PF02403.22 EOO03570.1 - 0.27 11.5 12.2 0.11 12.7 5.5 2.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 EOO03570.1 - 0.34 11.4 25.3 0.15 12.6 2.9 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region DASH_Hsk3 PF08227.11 EOO03570.1 - 0.34 11.3 9.7 2.7 8.4 3.3 3.6 3 1 1 4 4 3 0 DASH complex subunit Hsk3 like Lectin_N PF03954.14 EOO03570.1 - 0.37 10.5 6.0 1.3 8.7 2.6 2.8 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Spc24 PF08286.11 EOO03570.1 - 0.4 10.9 16.0 5.1 7.4 0.7 3.4 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF3450 PF11932.8 EOO03570.1 - 0.41 9.9 21.7 0.095 12.0 4.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) BLOC1_2 PF10046.9 EOO03570.1 - 0.42 11.0 7.0 0.75 10.1 2.6 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tup_N PF08581.10 EOO03570.1 - 0.59 10.5 13.3 0.34 11.2 0.3 2.8 2 1 1 3 3 2 0 Tup N-terminal HAUS-augmin3 PF14932.6 EOO03570.1 - 0.69 9.4 17.0 0.021 14.4 7.9 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EOO03570.1 - 0.77 10.4 17.3 1.1 9.9 2.7 3.6 1 1 2 3 3 3 0 SlyX FlxA PF14282.6 EOO03570.1 - 0.87 9.6 10.5 0.064 13.2 4.3 2.3 2 1 0 2 2 2 0 FlxA-like protein TMF_DNA_bd PF12329.8 EOO03570.1 - 0.96 9.5 13.9 0.87 9.6 0.4 3.8 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding Speriolin_N PF15058.6 EOO03570.1 - 1 9.4 4.1 1.2 9.2 0.1 2.1 1 1 1 2 2 2 0 Speriolin N terminus FapA PF03961.13 EOO03570.1 - 1 7.9 5.6 0.36 9.4 2.8 1.5 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF724 PF05266.14 EOO03570.1 - 1 9.2 11.1 0.18 11.6 4.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4472 PF14739.6 EOO03570.1 - 1 10.1 14.5 8.2 7.2 5.4 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4472) Lebercilin PF15619.6 EOO03570.1 - 1 9.0 25.4 0.066 12.9 10.7 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF2730 PF10805.8 EOO03570.1 - 1.1 9.4 4.6 3 8.0 0.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) SKA2 PF16740.5 EOO03570.1 - 1.3 8.9 10.1 0.57 10.0 5.0 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Syntaxin-6_N PF09177.11 EOO03570.1 - 1.7 9.3 8.9 5.9 7.5 4.8 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal OmpH PF03938.14 EOO03570.1 - 2.1 8.7 13.5 16 5.8 13.5 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 EOO03570.1 - 2.3 8.4 6.9 1.1 9.5 3.7 2.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family YlqD PF11068.8 EOO03570.1 - 2.6 8.4 13.5 1.7 9.1 6.9 2.6 1 1 1 2 2 2 0 YlqD protein UPF0242 PF06785.11 EOO03570.1 - 2.9 8.0 19.0 0.32 11.1 4.0 2.6 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus GrpE PF01025.19 EOO03570.1 - 3.5 7.3 11.9 3.2 7.4 0.5 2.5 1 1 1 2 2 2 0 GrpE Prefoldin_2 PF01920.20 EOO03570.1 - 5.1 7.1 13.0 0.99 9.4 0.7 3.5 1 1 3 5 5 5 0 Prefoldin subunit TSNAXIP1_N PF15739.5 EOO03570.1 - 5.2 7.5 14.7 0.55 10.6 3.0 3.1 1 1 3 4 4 4 0 Translin-associated factor X-interacting N-terminus BST2 PF16716.5 EOO03570.1 - 6.7 7.4 12.4 0.78 10.4 5.7 2.6 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Shugoshin_N PF07558.11 EOO03570.1 - 7.2 6.6 11.6 3.3 7.7 0.2 4.6 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region DUF5595 PF18077.1 EOO03570.1 - 7.5 6.7 7.7 6.6 6.9 0.3 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF5595) TMPIT PF07851.13 EOO03570.1 - 7.6 5.7 6.8 32 3.6 6.8 1.9 1 1 0 1 1 1 0 TMPIT-like protein APC_N_CC PF16689.5 EOO03570.1 - 8.4 6.6 15.0 0.31 11.1 0.9 4.0 2 1 2 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain Sec2p PF06428.11 EOO03570.1 - 9.5 6.3 12.5 0.48 10.4 2.5 3.0 1 1 3 4 4 4 0 GDP/GTP exchange factor Sec2p LMBR1 PF04791.16 EOO03570.1 - 9.7 5.0 8.1 11 4.7 8.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DENN PF02141.21 EOO03571.1 - 9.8e-40 136.5 0.1 1.7e-39 135.7 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EOO03571.1 - 6.3e-07 30.1 0.1 2.7e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.11 EOO03571.1 - 0.0066 17.0 5.5 0.03 14.9 5.5 2.1 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF3135 PF11333.8 EOO03571.1 - 0.12 12.7 4.4 0.25 11.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) IFT57 PF10498.9 EOO03571.1 - 0.23 10.4 12.3 0.013 14.5 5.5 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF5345 PF17280.2 EOO03571.1 - 1.5 8.8 3.9 1.2 9.2 0.6 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Hydant_A_N PF05378.13 EOO03572.1 - 1.2e-58 197.7 0.0 1.5e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 EOO03572.1 - 7.5e-18 64.8 0.0 3.4e-16 59.4 0.0 2.1 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Pkinase PF00069.25 EOO03573.1 - 1.6e-66 224.4 0.0 2.1e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO03573.1 - 1.3e-24 86.9 0.0 2e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EOO03573.1 - 0.00022 20.6 0.1 0.5 9.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RNase_HII PF01351.18 EOO03574.1 - 1.2e-46 159.1 0.0 1.5e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Steroid_dh PF02544.16 EOO03575.1 - 2.4e-19 69.8 1.6 5.8e-18 65.3 1.6 2.3 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EOO03575.1 - 7e-05 22.5 0.4 0.00016 21.2 0.3 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) HMA PF00403.26 EOO03576.1 - 4.2e-17 62.4 0.5 6.6e-17 61.7 0.5 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain ALG11_N PF15924.5 EOO03578.1 - 2.8e-63 213.8 0.1 8.7e-40 137.0 0.0 2.2 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EOO03578.1 - 3.1e-24 85.4 0.0 5e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EOO03578.1 - 1.2e-12 48.5 0.0 3.7e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EOO03578.1 - 0.0045 17.0 0.1 0.02 14.9 0.0 2.1 2 1 0 2 2 2 1 Glycosyltransferase Family 4 MoaE PF02391.17 EOO03578.1 - 0.078 13.3 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 MoaE protein rRNA_proc-arch PF13234.6 EOO03579.1 - 8.2e-92 308.0 2.1 2.3e-91 306.5 0.0 2.6 3 0 0 3 3 3 1 rRNA-processing arch domain DSHCT PF08148.12 EOO03579.1 - 6.4e-51 172.3 3.2 2e-50 170.6 2.5 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 EOO03579.1 - 2.4e-18 66.5 0.1 1.2e-17 64.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EOO03579.1 - 1.5e-07 31.7 0.1 8.8e-07 29.3 0.1 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO03579.1 - 2.3e-05 24.5 0.1 0.00018 21.5 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EOO03579.1 - 0.026 13.6 0.0 0.18 10.8 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 EOO03579.1 - 0.033 14.1 0.0 0.43 10.5 0.0 2.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EOO03579.1 - 0.065 13.5 0.0 0.67 10.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain DASH_Dad1 PF08649.10 EOO03580.1 - 7.5e-28 96.5 1.9 9e-28 96.2 1.9 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 EOO03580.1 - 0.039 13.9 0.1 0.05 13.6 0.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 CK2S PF15011.6 EOO03580.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Casein Kinase 2 substrate LSM PF01423.22 EOO03581.1 - 7.1e-20 70.5 0.1 8.2e-20 70.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain Cutinase PF01083.22 EOO03582.1 - 3.3e-28 98.9 0.1 3.3e-28 98.9 0.1 1.7 2 0 0 2 2 2 1 Cutinase SOG2 PF10428.9 EOO03582.1 - 6.5 5.8 21.4 9.4 5.3 21.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Aminotran_1_2 PF00155.21 EOO03583.1 - 8.5e-68 229.2 0.0 9.7e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EOO03583.1 - 0.00022 20.6 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EOO03583.1 - 0.0013 17.3 0.0 0.0025 16.4 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EOO03583.1 - 0.019 14.3 0.0 0.052 12.8 0.0 1.6 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EOO03583.1 - 0.055 12.4 0.0 0.17 10.8 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class-V Putative_PNPOx PF01243.20 EOO03584.1 - 0.00053 20.1 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ribosomal_60s PF00428.19 EOO03584.1 - 0.47 11.1 5.0 1.2 9.7 5.0 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein APH PF01636.23 EOO03585.1 - 0.0012 18.9 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EOO03585.1 - 0.045 13.3 0.4 0.1 12.2 0.4 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EOO03586.1 - 1.3e-61 208.4 0.0 1.3e-61 208.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EOO03586.1 - 0.00033 20.7 0.0 0.00044 20.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EOO03586.1 - 0.0047 15.8 0.0 0.0069 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) His_Phos_2 PF00328.22 EOO03587.1 - 0.089 12.1 1.8 0.16 11.3 1.8 1.4 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Tcf25 PF04910.14 EOO03588.1 - 3.3e-53 181.0 0.2 5.2e-53 180.4 0.2 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 UPF0239 PF06783.11 EOO03588.1 - 1.2 9.3 4.9 0.47 10.7 1.6 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) Pribosyl_synth PF14572.6 EOO03589.1 - 6.6e-43 146.9 2.1 1.1e-36 126.6 0.6 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EOO03589.1 - 2.2e-29 101.8 0.0 5.6e-29 100.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EOO03589.1 - 2.7e-15 56.3 0.5 5.4e-15 55.3 0.2 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EOO03589.1 - 0.095 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Glyco_hydro_61 PF03443.14 EOO03590.1 - 2.9e-35 122.1 0.0 3.9e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Epimerase PF01370.21 EOO03591.1 - 1e-11 44.8 0.0 1.5e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EOO03591.1 - 2.1e-10 40.1 0.0 3.4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EOO03591.1 - 1e-06 28.8 0.1 1.9e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EOO03591.1 - 1.1e-05 25.0 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EOO03591.1 - 0.0018 17.5 0.1 0.0029 16.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 EOO03591.1 - 0.036 14.6 0.0 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 EOO03591.1 - 0.16 11.5 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Lactonase PF10282.9 EOO03592.1 - 1.4e-37 129.8 0.0 2e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Caskin1-CID PF16600.5 EOO03592.1 - 0.95 10.1 0.1 0.95 10.1 0.1 2.7 3 0 0 3 3 3 0 Caskin1 CASK-interaction domain tRNA_U5-meth_tr PF05958.11 EOO03593.1 - 1.5e-09 37.3 0.0 2e-07 30.4 0.0 2.9 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 EOO03593.1 - 0.00025 20.9 0.0 0.00053 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO03593.1 - 0.00037 21.1 0.0 0.00085 20.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EOO03593.1 - 0.00043 19.8 0.0 0.00069 19.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 EOO03593.1 - 0.0029 17.2 0.0 0.0058 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TRM PF02005.16 EOO03593.1 - 0.047 12.9 0.1 0.085 12.0 0.0 1.4 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase Cons_hypoth95 PF03602.15 EOO03593.1 - 0.084 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 EOO03593.1 - 0.15 12.7 0.0 0.39 11.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain ADH_N PF08240.12 EOO03594.1 - 1.4e-29 102.1 0.2 2.6e-29 101.3 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EOO03594.1 - 1.9e-22 79.6 0.2 3.1e-22 79.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EOO03594.1 - 0.00012 23.1 0.0 0.00022 22.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EOO03594.1 - 0.058 12.7 1.2 0.11 11.7 1.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EOO03594.1 - 0.09 12.2 1.0 0.29 10.6 1.4 1.7 2 0 0 2 2 2 0 short chain dehydrogenase ACP_syn_III_C PF08541.10 EOO03594.1 - 0.13 12.4 0.1 7.1 6.9 0.1 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal HSP70 PF00012.20 EOO03595.1 - 3.8e-259 860.9 5.5 4.3e-259 860.8 5.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EOO03595.1 - 7.1e-17 61.2 0.0 8.2e-16 57.7 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EOO03595.1 - 0.0021 17.8 0.0 0.0059 16.3 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EOO03595.1 - 0.0027 18.1 0.3 4.3 7.8 0.0 3.3 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 EOO03595.1 - 0.032 13.5 0.1 0.065 12.5 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 EOO03595.1 - 0.037 13.3 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 StbA protein BcrAD_BadFG PF01869.20 EOO03595.1 - 0.065 12.7 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family NOP19 PF10863.8 EOO03595.1 - 0.33 10.8 2.9 5.1 6.9 0.5 2.6 2 0 0 2 2 2 0 Nucleolar protein 19 RNA_pol_Rpb4 PF03874.16 EOO03596.1 - 1.6e-23 83.4 0.2 1.9e-23 83.1 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Mif2_N PF15624.6 EOO03597.1 - 1.2e-40 139.3 1.1 1.2e-40 139.3 1.1 3.2 2 1 0 2 2 2 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 EOO03597.1 - 1.7e-33 114.7 0.3 2.8e-33 114.0 0.3 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 EOO03597.1 - 2.4e-06 27.2 0.0 6.3e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Pyridoxal_deC PF00282.19 EOO03598.1 - 2.2e-15 56.3 0.0 3.2e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EOO03598.1 - 0.00053 19.1 0.0 0.0011 18.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EOO03598.1 - 0.0057 16.0 0.0 0.0091 15.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family TRF PF08558.10 EOO03599.1 - 1.3e-16 60.9 0.0 2.4e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 EOO03599.1 - 1.8e-06 28.0 0.0 3.4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EOO03599.1 - 0.019 15.2 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF3128 PF11326.8 EOO03601.1 - 1.8e-26 92.3 0.4 2.5e-26 91.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) CS PF04969.16 EOO03602.1 - 2.1e-07 31.8 0.1 3.4e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 CS domain Cwf_Cwc_15 PF04889.12 EOO03602.1 - 0.0099 15.6 3.8 0.015 15.0 3.8 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Hexokinase_2 PF03727.16 EOO03602.1 - 0.48 9.8 1.1 7.4 5.9 0.1 2.0 1 1 1 2 2 2 0 Hexokinase TFIIA PF03153.13 EOO03603.1 - 0.33 10.9 3.4 0.42 10.5 3.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aldedh PF00171.22 EOO03604.1 - 2e-186 620.0 0.2 2.3e-186 619.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Alg14 PF08660.11 EOO03605.1 - 2.2e-45 154.7 0.0 2.9e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DBR1 PF05011.13 EOO03606.1 - 1.3e-49 168.2 0.0 3e-49 167.0 0.0 1.6 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EOO03606.1 - 1.1e-05 26.0 0.1 1.8e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Asparaginase_2 PF01112.18 EOO03607.1 - 6.3e-46 156.8 9.4 6.1e-45 153.6 9.3 2.0 1 1 0 1 1 1 1 Asparaginase PRMT5_TIM PF17285.2 EOO03608.1 - 3.5e-73 245.9 0.0 5.1e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 EOO03608.1 - 1.4e-65 220.4 0.0 2.5e-65 219.5 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EOO03608.1 - 1.5e-60 204.1 0.0 2.3e-60 203.5 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain MRP-S25 PF13741.6 EOO03609.1 - 2.2e-64 217.1 9.4 4.5e-61 206.3 3.4 2.0 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 EOO03609.1 - 0.0038 17.5 4.3 0.0049 17.1 2.4 2.0 2 1 0 2 2 2 1 Mitochondrial ribosomal protein S23 RasGEF PF00617.19 EOO03610.1 - 2e-46 158.4 0.0 3.3e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EOO03610.1 - 1.5e-13 50.8 0.2 3.5e-13 49.7 0.2 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif PP1_bind PF15276.6 EOO03610.1 - 2.4 8.5 9.6 0.73 10.2 0.1 4.6 4 0 0 4 4 4 0 Protein phosphatase 1 binding MFS_1 PF07690.16 EOO03611.1 - 2.5 7.0 29.1 12 4.7 28.9 1.9 1 1 0 1 1 1 0 Major Facilitator Superfamily Y_phosphatase2 PF03162.13 EOO03612.1 - 1.1e-45 155.1 0.0 1.7e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EOO03612.1 - 2.5e-11 44.0 0.0 3.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EOO03612.1 - 0.00021 21.1 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EOO03612.1 - 0.0039 16.8 0.0 0.0068 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ribonuclease_3 PF00636.26 EOO03613.1 - 3.4e-35 120.8 0.0 6.9e-18 65.2 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 EOO03613.1 - 1.9e-24 85.6 0.0 7.8e-24 83.7 0.0 2.1 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 EOO03613.1 - 8.9e-21 74.4 0.0 1.6e-07 31.5 0.0 4.4 4 1 0 4 4 4 3 Ribonuclease-III-like Helicase_C PF00271.31 EOO03613.1 - 1.2e-15 57.9 0.0 2.3e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.32 EOO03614.1 - 5.5e-14 52.3 14.8 0.082 13.8 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.6 EOO03614.1 - 0.012 16.1 2.9 0.3 11.6 0.1 4.3 5 1 1 6 6 6 0 PQQ-like domain DUF627 PF04781.12 EOO03614.1 - 0.029 14.4 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Sigma70_r1_2 PF00140.20 EOO03614.1 - 0.1 12.7 0.6 0.2 11.7 0.6 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Syntaxin_2 PF14523.6 EOO03616.1 - 7.6e-28 96.9 6.4 3.9e-27 94.6 2.7 2.3 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EOO03616.1 - 1.1e-15 57.4 0.4 2.7e-15 56.1 0.4 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EOO03616.1 - 2.4e-05 24.1 9.2 4.7e-05 23.2 9.2 1.6 1 1 0 1 1 1 1 Syntaxin Synaptobrevin PF00957.21 EOO03616.1 - 0.0058 16.4 0.1 0.026 14.3 0.1 2.2 2 0 0 2 2 2 1 Synaptobrevin T3SSipB PF16535.5 EOO03616.1 - 0.017 15.6 5.0 0.017 15.6 5.0 2.3 3 0 0 3 3 3 0 Type III cell invasion protein SipB Prominin PF05478.11 EOO03616.1 - 0.019 13.0 4.2 0.066 11.2 4.1 1.9 1 1 0 1 1 1 0 Prominin DUF883 PF05957.13 EOO03616.1 - 0.047 14.3 9.2 0.77 10.4 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) T2SSF PF00482.23 EOO03616.1 - 0.096 12.6 2.3 0.13 12.2 0.6 2.2 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F Nre_C PF04895.12 EOO03616.1 - 0.1 12.5 0.2 0.1 12.5 0.2 2.0 3 0 0 3 3 3 0 Archaeal Nre, C-terminal PAH PF02671.21 EOO03616.1 - 0.34 11.1 0.0 0.34 11.1 0.0 2.6 2 1 1 3 3 3 0 Paired amphipathic helix repeat MCPsignal PF00015.21 EOO03616.1 - 1.1 9.0 9.8 0.6 9.9 1.9 2.7 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 EOO03616.1 - 1.4 9.0 5.9 8.7 6.4 1.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 EOO03616.1 - 4.7 7.8 11.7 6.3e+02 0.9 11.7 2.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 RHD3 PF05879.12 EOO03617.1 - 0 1063.3 0.0 0 1063.0 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EOO03617.1 - 3.2e-07 29.9 0.1 5.2e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 EOO03617.1 - 3.4e-06 27.2 0.0 8.6e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EOO03617.1 - 0.00013 22.1 0.0 0.00034 20.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EOO03617.1 - 0.0009 19.5 1.2 0.0018 18.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 EOO03617.1 - 0.02 14.2 0.1 0.037 13.3 0.1 1.4 1 0 0 1 1 1 0 Septin Cys_Met_Meta_PP PF01053.20 EOO03617.1 - 0.023 13.2 0.1 0.038 12.5 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Carn_acyltransf PF00755.20 EOO03618.1 - 2.4e-209 696.8 0.0 7.2e-209 695.2 0.0 1.6 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase HBD PF18534.1 EOO03618.1 - 0.1 12.7 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Helical bundle domain DUF2244 PF10003.9 EOO03619.1 - 1.6 8.4 5.9 0.11 12.2 0.5 1.8 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF4129 PF13559.6 EOO03620.1 - 0.00035 20.8 0.1 0.00083 19.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) NICE-3 PF07406.11 EOO03620.1 - 0.023 14.7 7.5 0.14 12.1 0.1 2.6 3 0 0 3 3 3 0 NICE-3 protein YrvL PF14184.6 EOO03620.1 - 0.077 13.1 1.0 0.16 12.1 0.9 1.4 1 1 0 1 1 1 0 Regulatory protein YrvL DEAD PF00270.29 EOO03621.1 - 8.4e-36 123.4 0.1 3.7e-35 121.3 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.6 EOO03621.1 - 0.00016 21.8 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) MarR_2 PF12802.7 EOO03621.1 - 0.0068 16.3 0.1 0.81 9.6 0.1 3.3 2 0 0 2 2 2 1 MarR family AAA_22 PF13401.6 EOO03621.1 - 0.23 11.7 0.9 2.7 8.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain CTNNB1_binding PF08347.11 EOO03621.1 - 1.1 9.4 7.3 2 8.6 7.3 1.4 1 0 0 1 1 1 0 N-terminal CTNNB1 binding MAJIN PF15077.6 EOO03621.1 - 5.2 6.8 8.7 8 6.2 8.7 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Tfb4 PF03850.14 EOO03622.1 - 2.9e-85 286.1 12.4 3.1e-63 213.8 0.8 2.0 2 0 0 2 2 2 2 Transcription factor Tfb4 Rogdi_lz PF10259.9 EOO03622.1 - 0.064 12.7 0.3 0.09 12.2 0.3 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Smg4_UPF3 PF03467.15 EOO03623.1 - 3.1e-49 167.3 0.0 3.1e-49 167.3 0.0 3.2 4 0 0 4 4 4 1 Smg-4/UPF3 family RRM_1 PF00076.22 EOO03623.1 - 2.7e-06 27.1 0.0 9.5e-05 22.1 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_18 PF12833.7 EOO03623.1 - 0.094 13.0 0.0 0.45 10.8 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain ATP-grasp_2 PF08442.10 EOO03624.1 - 1.1e-77 260.2 0.5 1.1e-77 260.2 0.5 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EOO03624.1 - 1.8e-26 92.8 0.6 3.3e-26 91.9 0.6 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EOO03624.1 - 3.4e-08 33.2 0.2 8.2e-08 32.0 0.2 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EOO03624.1 - 4e-05 23.5 1.3 0.0016 18.3 0.2 2.7 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain p450 PF00067.22 EOO03625.1 - 8e-50 169.9 0.0 1.1e-49 169.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cerato-platanin PF07249.12 EOO03625.1 - 0.17 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Cerato-platanin Perilipin PF03036.16 EOO03626.1 - 0.015 14.4 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Perilipin family KASH_CCD PF14662.6 EOO03627.1 - 2.8e-05 24.0 6.9 3.8e-05 23.6 6.9 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH BST2 PF16716.5 EOO03627.1 - 0.00051 20.6 8.4 0.00085 19.9 7.1 1.9 1 1 1 2 2 2 1 Bone marrow stromal antigen 2 ERM PF00769.19 EOO03627.1 - 0.0031 17.4 7.4 0.0052 16.6 7.4 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Borrelia_P83 PF05262.11 EOO03627.1 - 0.0059 15.1 7.9 0.0094 14.5 7.9 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein DUF2353 PF09789.9 EOO03627.1 - 0.0072 15.7 10.1 0.0096 15.3 10.1 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) ATG16 PF08614.11 EOO03627.1 - 0.019 15.2 15.4 0.018 15.2 13.0 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) WXG100 PF06013.12 EOO03627.1 - 0.1 12.9 4.0 0.5 10.6 2.4 2.6 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF812 PF05667.11 EOO03627.1 - 0.18 10.7 9.2 0.35 9.7 9.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF4201 PF13870.6 EOO03627.1 - 0.19 11.4 12.8 0.41 10.4 12.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) CdvA PF18822.1 EOO03627.1 - 0.25 11.2 9.3 0.8 9.5 0.4 2.4 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Exonuc_VII_L PF02601.15 EOO03627.1 - 0.32 10.5 4.0 0.44 10.1 4.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FtsL PF04999.13 EOO03627.1 - 0.39 10.7 2.3 0.74 9.9 2.3 1.4 1 0 0 1 1 1 0 Cell division protein FtsL YabA PF06156.13 EOO03627.1 - 0.49 11.1 8.7 0.55 10.9 6.8 1.9 1 1 1 2 2 2 0 Initiation control protein YabA EzrA PF06160.12 EOO03627.1 - 0.56 8.3 8.3 0.75 7.9 8.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA HlyD_2 PF12700.7 EOO03627.1 - 0.64 8.7 5.3 0.8 8.4 5.3 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Golgin_A5 PF09787.9 EOO03627.1 - 0.76 9.2 9.4 1.3 8.4 9.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 CENP-H PF05837.12 EOO03627.1 - 0.76 10.2 14.3 4.4 7.7 3.9 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Atg14 PF10186.9 EOO03627.1 - 1 8.4 6.4 1.5 7.9 6.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 EOO03627.1 - 1.1 9.4 7.9 1.7 8.8 7.9 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 EOO03627.1 - 1.2 7.0 3.7 1.5 6.6 3.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.8 EOO03627.1 - 1.3 8.3 9.7 1.9 7.7 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 EOO03627.1 - 1.6 8.8 13.4 3.1 7.8 13.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3584 PF12128.8 EOO03627.1 - 1.6 6.2 11.6 2 5.8 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_II PF06009.12 EOO03627.1 - 2 8.4 5.8 3 7.9 5.8 1.2 1 0 0 1 1 1 0 Laminin Domain II APG6_N PF17675.1 EOO03627.1 - 2.2 8.8 17.6 5.6 7.5 17.6 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3053 PF11254.8 EOO03627.1 - 2.4 7.7 5.9 0.22 11.1 1.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) Rootletin PF15035.6 EOO03627.1 - 4.1 7.4 15.4 5.2 7.0 9.0 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion GBP_C PF02841.14 EOO03627.1 - 5.9 6.2 11.5 9.4 5.5 11.5 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF724 PF05266.14 EOO03627.1 - 6.7 6.5 9.5 11 5.8 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TMPIT PF07851.13 EOO03627.1 - 7.1 5.8 9.3 9.4 5.4 1.5 1.9 1 1 1 2 2 2 0 TMPIT-like protein GAS PF13851.6 EOO03627.1 - 9.2 5.6 18.8 2 7.7 14.5 2.0 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 EOO03627.1 - 9.6 5.5 10.0 4.4 6.6 6.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ald_Xan_dh_C2 PF02738.18 EOO03628.1 - 6.6e-206 685.0 0.0 9.4e-206 684.5 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EOO03628.1 - 6.5e-49 165.9 0.0 1.3e-48 165.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 EOO03628.1 - 4.5e-31 107.5 0.0 1e-30 106.3 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 EOO03628.1 - 5.1e-31 106.9 1.1 1e-30 105.9 0.1 2.1 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 EOO03628.1 - 6.9e-30 102.9 0.1 1.4e-29 101.9 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 EOO03628.1 - 2.1e-08 34.0 1.7 3.7e-08 33.2 0.1 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 EOO03628.1 - 0.098 12.7 0.1 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 DUF218 domain Ras PF00071.22 EOO03630.1 - 1.5e-45 154.7 0.0 1.9e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EOO03630.1 - 1.4e-18 67.3 0.0 2.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EOO03630.1 - 5.2e-05 22.8 0.0 0.00012 21.6 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF4850 PF16142.5 EOO03630.1 - 0.17 11.3 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) Band_7 PF01145.25 EOO03631.1 - 2.3e-28 99.4 4.3 3.9e-28 98.6 4.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EOO03631.1 - 0.03 14.0 0.3 0.048 13.4 0.3 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Snf7 PF03357.21 EOO03632.1 - 2.6e-22 79.2 5.7 2.6e-22 79.2 5.7 2.0 1 1 1 2 2 2 1 Snf7 DUF3484 PF11983.8 EOO03632.1 - 0.25 12.5 4.4 0.32 12.1 2.7 2.1 1 1 1 2 2 2 0 Membrane-attachment and polymerisation-promoting switch Gon7 PF08738.10 EOO03632.1 - 0.31 11.2 2.8 0.85 9.7 0.3 2.3 2 0 0 2 2 2 0 Gon7 family Peptidase_C2 PF00648.21 EOO03633.1 - 9.6e-64 215.2 3.3 1.3e-62 211.5 3.3 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease Rrn6 PF10214.9 EOO03633.1 - 5.5 5.3 10.2 0.082 11.4 0.3 2.0 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Dicty_REP PF05086.12 EOO03633.1 - 7.8 4.3 12.6 12 3.8 12.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mcl1_mid PF12341.8 EOO03634.1 - 1.6e-99 333.0 0.0 4.7e-98 328.2 0.0 2.4 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EOO03634.1 - 3e-24 84.8 0.3 1.6e-08 35.0 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO03634.1 - 4.8e-18 65.2 0.0 3e-05 24.2 0.1 7.4 2 1 5 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EOO03634.1 - 4e-06 26.1 0.0 1.3e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 EOO03634.1 - 6e-06 26.3 0.1 0.0034 17.3 0.1 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EOO03634.1 - 6.5e-05 22.0 0.0 2.1 7.2 0.0 3.6 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EOO03634.1 - 0.0005 19.9 0.6 1.8 8.6 0.0 5.0 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat MMS1_N PF10433.9 EOO03634.1 - 0.0032 16.2 0.0 0.071 11.7 0.0 2.6 1 1 1 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40_3 PF15911.5 EOO03634.1 - 0.0047 16.9 0.0 0.74 9.9 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat DNA_pol_alpha_N PF12254.8 EOO03634.1 - 0.11 12.6 3.3 0.32 11.1 3.3 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal SPO22 PF08631.10 EOO03635.1 - 2.5e-42 145.3 5.4 2e-40 139.0 0.7 2.9 2 1 1 3 3 3 2 Meiosis protein SPO22/ZIP4 like Hydantoinase_B PF02538.14 EOO03636.1 - 9.4e-86 288.3 10.0 2.6e-49 168.0 7.7 2.0 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase Cir_N PF10197.9 EOO03638.1 - 1.3e-06 28.5 2.0 1.3e-06 28.5 2.0 5.2 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR NUDIX PF00293.28 EOO03639.1 - 4.4e-09 36.5 1.4 6e-09 36.0 1.4 1.2 1 0 0 1 1 1 1 NUDIX domain Ndc1_Nup PF09531.10 EOO03640.1 - 3.2e-98 330.0 0.0 3.6e-98 329.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Peptidase_Prp PF04327.12 EOO03640.1 - 0.063 13.5 0.0 0.2 11.9 0.0 1.9 1 1 0 1 1 1 0 Cysteine protease Prp CTU2 PF10288.9 EOO03640.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-HIT PF04438.16 EOO03641.1 - 1.7e-09 37.4 8.3 2.5e-09 36.8 8.3 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 EOO03641.1 - 2.1 8.5 8.5 4.5 7.5 8.5 1.5 1 0 0 1 1 1 0 MYND finger KxDL PF10241.9 EOO03643.1 - 4.5e-30 103.8 3.2 6.1e-30 103.3 3.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein LSM14 PF12701.7 EOO03645.1 - 1.2e-31 108.6 0.1 1.9e-31 107.9 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 EOO03645.1 - 4.4e-21 75.7 2.5 1.2e-20 74.4 2.5 1.7 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.6 EOO03645.1 - 2.5e-07 30.7 0.0 4.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain TFIIA PF03153.13 EOO03645.1 - 2.9 7.8 9.7 3.9 7.4 9.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aldedh PF00171.22 EOO03646.1 - 8.9e-139 462.9 0.1 1e-138 462.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EOO03646.1 - 0.00029 20.0 0.1 0.0047 16.0 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) KIP1 PF07765.12 EOO03646.1 - 0.053 13.6 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 KIP1-like protein G_glu_transpept PF01019.21 EOO03648.1 - 5.4e-147 490.6 3.8 4.6e-100 335.8 0.5 2.0 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase adh_short PF00106.25 EOO03649.1 - 7.8e-26 90.7 0.0 1.3e-25 90.0 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03649.1 - 3.5e-21 75.9 0.0 4.5e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO03649.1 - 0.006 16.5 0.0 0.0089 15.9 0.0 1.4 1 1 0 1 1 1 1 KR domain UNC45-central PF11701.8 EOO03650.1 - 5.7e-57 192.0 0.3 1.2e-55 187.6 0.1 3.2 3 1 0 3 3 3 1 Myosin-binding striated muscle assembly central Ras PF00071.22 EOO03651.1 - 1.9e-18 66.6 0.0 2.6e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EOO03651.1 - 2.2e-06 27.9 0.0 4.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EOO03651.1 - 0.0032 16.9 0.0 0.051 13.0 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Cir_N PF10197.9 EOO03651.1 - 0.049 13.8 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR G-alpha PF00503.20 EOO03651.1 - 0.069 12.3 0.1 0.09 11.9 0.1 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 EOO03651.1 - 0.071 12.9 0.3 0.52 10.1 0.2 2.1 1 1 1 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EOO03651.1 - 0.1 12.7 0.0 0.17 11.9 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EOO03651.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PIG-H PF10181.9 EOO03653.1 - 1.4e-27 95.3 0.1 2.5e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Actin PF00022.19 EOO03654.1 - 3.5e-66 223.5 0.0 1.5e-63 214.9 0.0 2.0 1 1 0 1 1 1 1 Actin FtsA PF14450.6 EOO03654.1 - 0.011 16.1 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 0 Cell division protein FtsA MreB_Mbl PF06723.13 EOO03654.1 - 0.035 12.9 0.1 1.6 7.5 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Skp1_POZ PF03931.15 EOO03655.1 - 6.8e-09 35.8 0.0 9.7e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain OAS1_C PF10421.9 EOO03655.1 - 0.073 12.6 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus DUF1987 PF09345.10 EOO03656.1 - 0.12 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) MFS_1 PF07690.16 EOO03657.1 - 0.00081 18.4 5.8 0.0024 16.9 0.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OB_NTP_bind PF07717.16 EOO03658.1 - 2.3e-22 79.2 0.1 1.1e-21 76.9 0.0 2.3 3 0 0 3 3 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EOO03658.1 - 4.7e-19 68.7 0.0 1.1e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EOO03658.1 - 1.5e-10 41.4 0.0 9.7e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EOO03658.1 - 1.1e-07 31.8 0.2 2.4e-07 30.7 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EOO03658.1 - 1.8e-07 31.5 0.1 5.9e-07 29.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EOO03658.1 - 0.00018 21.3 0.0 0.00031 20.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EOO03658.1 - 0.00087 19.0 0.2 0.003 17.2 0.2 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.15 EOO03658.1 - 0.014 15.4 0.1 1.9 8.5 0.1 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 EOO03658.1 - 0.017 15.6 0.0 0.036 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EOO03658.1 - 0.025 13.6 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 EOO03658.1 - 0.057 13.8 0.2 1.4 9.4 0.1 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.14 EOO03658.1 - 0.074 13.0 0.5 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain DUF2075 PF09848.9 EOO03658.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Proteasome PF00227.26 EOO03659.1 - 4.6e-57 192.6 0.0 6.1e-33 113.9 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EOO03659.1 - 1.2e-10 40.8 0.3 3.2e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Sugar_tr PF00083.24 EOO03660.1 - 2.4e-96 323.4 21.8 2.8e-96 323.1 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO03660.1 - 4.3e-24 85.1 50.1 9.2e-22 77.4 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA PF00004.29 EOO03661.1 - 1.7e-56 190.3 0.0 2.8e-38 131.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EOO03661.1 - 3.3e-11 43.6 0.2 0.0001 22.6 0.0 3.8 2 2 1 3 3 3 2 AAA domain AAA_lid_3 PF17862.1 EOO03661.1 - 5.3e-09 35.7 0.2 1.1e-08 34.8 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EOO03661.1 - 9.2e-09 35.9 0.0 0.0024 18.3 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 EOO03661.1 - 1.6e-07 31.6 0.0 0.00022 21.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EOO03661.1 - 1.7e-07 30.8 0.0 0.013 14.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 EOO03661.1 - 4.6e-07 30.1 0.0 0.023 14.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EOO03661.1 - 7.2e-07 29.3 0.0 0.0009 19.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EOO03661.1 - 1.6e-06 27.9 0.1 0.04 13.7 0.1 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EOO03661.1 - 5.8e-06 26.6 0.0 0.022 15.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 EOO03661.1 - 1.1e-05 24.9 0.2 0.007 15.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EOO03661.1 - 1.4e-05 25.6 0.0 0.063 13.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 EOO03661.1 - 1.7e-05 24.9 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EOO03661.1 - 3.5e-05 23.4 0.4 0.032 13.7 0.0 2.6 3 0 0 3 3 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 EOO03661.1 - 4.8e-05 23.2 0.1 0.017 14.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EOO03661.1 - 5.7e-05 22.9 0.0 0.41 10.3 0.0 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain NACHT PF05729.12 EOO03661.1 - 7.6e-05 22.7 1.8 3.9 7.4 0.0 3.7 4 0 0 4 4 3 1 NACHT domain ATPase_2 PF01637.18 EOO03661.1 - 0.00018 21.5 0.3 28 4.5 0.0 4.1 2 2 1 4 4 4 0 ATPase domain predominantly from Archaea TsaE PF02367.17 EOO03661.1 - 0.00043 20.3 0.0 0.24 11.4 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE CDC48_2 PF02933.17 EOO03661.1 - 0.00081 19.1 0.2 0.01 15.6 0.0 2.6 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), domain 2 ATPase PF06745.13 EOO03661.1 - 0.00093 18.6 0.5 0.02 14.3 0.1 2.8 2 1 1 3 3 3 1 KaiC NB-ARC PF00931.22 EOO03661.1 - 0.00093 18.4 0.1 1.4 8.1 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain ABC_tran PF00005.27 EOO03661.1 - 0.0012 19.3 0.3 0.022 15.3 0.1 2.5 2 0 0 2 2 2 1 ABC transporter IstB_IS21 PF01695.17 EOO03661.1 - 0.0026 17.5 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 EOO03661.1 - 0.0068 16.2 0.0 0.36 10.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 EOO03661.1 - 0.0075 16.1 0.0 0.35 10.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EOO03661.1 - 0.01 15.3 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 EOO03661.1 - 0.01 16.1 0.0 0.76 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EOO03661.1 - 0.012 16.0 0.0 4 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EOO03661.1 - 0.012 15.6 0.5 9.1 6.2 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit IPT PF01745.16 EOO03661.1 - 0.018 14.5 0.1 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase AAA_25 PF13481.6 EOO03661.1 - 0.02 14.5 0.0 2 7.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 EOO03661.1 - 0.022 15.1 0.3 0.42 10.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain CDC48_N PF02359.18 EOO03661.1 - 0.023 14.8 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Sigma54_activ_2 PF14532.6 EOO03661.1 - 0.027 14.6 0.1 15 5.7 0.0 3.3 3 1 0 3 3 3 0 Sigma-54 interaction domain AAA_29 PF13555.6 EOO03661.1 - 0.031 14.0 0.0 5.9 6.7 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_11 PF13086.6 EOO03661.1 - 0.031 14.1 0.0 0.75 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EOO03661.1 - 0.043 13.7 0.0 13 5.7 0.0 2.9 3 0 0 3 3 3 0 Rad17 P-loop domain TniB PF05621.11 EOO03661.1 - 0.055 12.9 0.8 7 6.0 0.1 3.9 3 2 1 4 4 4 0 Bacterial TniB protein Parvo_NS1 PF01057.17 EOO03661.1 - 0.079 12.0 0.0 0.29 10.2 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DNA_pol3_delta2 PF13177.6 EOO03661.1 - 0.11 12.3 0.1 26 4.6 0.0 3.4 3 1 0 3 3 3 0 DNA polymerase III, delta subunit DUF2075 PF09848.9 EOO03661.1 - 0.17 11.1 0.1 0.79 8.9 0.1 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Metallophos PF00149.28 EOO03662.1 - 2.3e-30 106.6 0.0 6e-26 92.2 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EOO03662.1 - 0.031 13.9 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 EOO03662.1 - 0.11 12.9 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Sporozoite_P67 PF05642.11 EOO03662.1 - 0.38 8.8 3.6 0.54 8.3 3.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Aim19 PF10315.9 EOO03664.1 - 0.00026 21.3 1.4 0.00052 20.3 1.4 1.6 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 FOXP-CC PF16159.5 EOO03665.1 - 0.0096 16.5 4.2 0.31 11.7 0.1 2.3 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 EOO03665.1 - 0.044 14.3 1.6 1.6 9.3 0.4 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EOO03665.1 - 0.12 13.2 4.0 9.7 7.3 1.0 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger DUF1977 PF09320.11 EOO03666.1 - 6e-30 103.6 0.7 6e-30 103.6 0.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 EOO03666.1 - 1.5e-19 69.9 0.3 2.5e-19 69.1 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Glyco_transf_34 PF05637.12 EOO03667.1 - 3.3e-71 239.8 0.0 4.1e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 EOO03667.1 - 0.0027 17.3 0.0 0.064 12.8 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF273 OppC_N PF12911.7 EOO03667.1 - 0.0077 16.2 0.1 0.02 14.9 0.1 1.8 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C DUF5447 PF17525.2 EOO03667.1 - 0.054 14.0 0.0 0.17 12.4 0.0 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5447) DUF4203 PF13886.6 EOO03668.1 - 4.7e-41 140.7 12.2 6e-41 140.3 12.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Cnd3 PF12719.7 EOO03669.1 - 1.3e-94 316.7 4.0 1.5e-94 316.5 0.5 2.6 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EOO03669.1 - 2.4e-10 40.7 9.9 4.8e-06 26.9 1.3 4.3 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EOO03669.1 - 2.6e-08 33.4 11.7 0.087 13.1 0.0 8.2 9 0 0 9 9 9 3 HEAT repeat Cnd1 PF12717.7 EOO03669.1 - 0.068 13.2 10.4 0.46 10.5 0.1 5.4 5 2 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 FANCI_HD1 PF14679.6 EOO03669.1 - 0.072 13.1 0.7 0.25 11.3 0.0 2.3 3 0 0 3 3 3 0 FANCI helical domain 1 RTP1_C1 PF10363.9 EOO03669.1 - 0.45 10.7 2.2 13 6.0 0.0 3.9 3 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EOO03669.1 - 1.5 9.4 14.0 1.5 9.4 1.1 6.1 5 2 3 8 8 8 0 HEAT-like repeat RRM_1 PF00076.22 EOO03670.1 - 6e-56 186.2 0.1 3.3e-18 65.3 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EOO03670.1 - 1.9e-07 31.0 0.9 0.0067 16.2 0.0 3.6 2 1 1 3 3 3 2 Rrp7 RRM-like N-terminal domain PHM7_cyt PF14703.6 EOO03670.1 - 0.00015 22.0 6.7 3.3 7.9 0.0 6.6 5 4 3 8 8 8 2 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 EOO03670.1 - 0.00015 21.8 0.0 12 6.0 0.0 3.9 3 0 0 3 3 3 3 RNA recognition motif HGAL PF15666.5 EOO03671.1 - 0.28 11.3 2.9 0.2 11.8 0.8 1.9 2 0 0 2 2 2 0 Germinal center-associated lymphoma DUF4510 PF14971.6 EOO03672.1 - 0.044 14.1 2.5 0.12 12.7 2.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) HU-CCDC81_bac_1 PF18174.1 EOO03672.1 - 0.21 11.5 0.2 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 1 Matrilin_ccoil PF10393.9 EOO03672.1 - 0.4 10.6 2.5 0.62 10.0 1.1 2.0 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin CorA PF01544.18 EOO03673.1 - 5.4e-05 22.7 0.1 8.6e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AMP-binding PF00501.28 EOO03674.1 - 1.9e-73 247.5 0.0 2.2e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EOO03674.1 - 3.5e-19 69.6 0.0 1e-18 68.1 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pectate_lyase_3 PF12708.7 EOO03675.1 - 5.6e-97 323.8 20.1 1.9e-82 276.3 6.6 3.0 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EOO03675.1 - 1.3e-06 27.9 3.3 0.0082 15.8 0.3 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Cation_ATPase_C PF00689.21 EOO03676.1 - 8.5e-45 152.7 7.5 8.5e-45 152.7 7.5 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EOO03676.1 - 6.3e-34 117.1 0.3 6.3e-34 117.1 0.3 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EOO03676.1 - 3.3e-24 84.8 0.0 6.2e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EOO03676.1 - 5.8e-17 62.7 0.4 4.5e-16 59.8 0.4 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EOO03676.1 - 2.7e-05 24.0 0.4 0.00011 22.1 0.6 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EOO03676.1 - 5.4e-05 22.8 0.1 0.00041 20.0 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus LptF_LptG PF03739.14 EOO03676.1 - 1 8.1 8.1 0.2 10.5 1.4 2.7 3 0 0 3 3 3 0 Lipopolysaccharide export system permease LptF/LptG FAD_binding_4 PF01565.23 EOO03677.1 - 3.7e-24 85.0 6.1 1.1e-23 83.4 5.1 2.1 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 EOO03677.1 - 0.00049 20.1 0.0 0.0021 18.1 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like ALO PF04030.14 EOO03677.1 - 0.11 12.2 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Cwf_Cwc_15 PF04889.12 EOO03678.1 - 0.072 12.8 13.2 0.68 9.6 3.0 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Afi1 PF07792.12 EOO03678.1 - 6.9 7.2 6.6 2.3 8.7 0.7 2.4 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Methyltransf_23 PF13489.6 EOO03679.1 - 2.8e-15 56.5 0.0 4.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO03679.1 - 0.00077 20.2 0.0 0.038 14.7 0.0 2.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO03679.1 - 0.0037 17.9 0.0 0.5 11.0 0.0 3.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO03679.1 - 0.029 15.1 0.0 34 5.2 0.0 3.3 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.6 EOO03679.1 - 0.041 13.7 0.0 0.48 10.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DUF4628 PF15429.6 EOO03679.1 - 0.043 13.5 0.2 0.059 13.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) Surp PF01805.20 EOO03680.1 - 2.6e-09 36.9 0.1 6.7e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Surp module DASH_Duo1 PF08651.10 EOO03681.1 - 1.4e-31 108.1 0.4 2e-31 107.6 0.4 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 Androgen_recep PF02166.16 EOO03681.1 - 0.095 11.5 1.2 0.13 11.1 1.2 1.1 1 0 0 1 1 1 0 Androgen receptor DUF1682 PF07946.14 EOO03681.1 - 0.2 10.8 7.9 0.13 11.4 6.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) zf-CHY PF05495.12 EOO03684.1 - 2.8e-11 43.8 11.8 2.8e-11 43.8 11.8 3.4 2 1 0 2 2 2 1 CHY zinc finger RWD PF05773.22 EOO03684.1 - 0.043 14.1 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 RWD domain Mu-like_Com PF10122.9 EOO03684.1 - 4.8 6.7 6.1 0.55 9.7 0.2 2.6 2 1 1 3 3 3 0 Mu-like prophage protein Com zinc_ribbon_15 PF17032.5 EOO03684.1 - 9.4 7.1 23.7 3.1 8.6 0.0 3.5 3 1 0 3 3 3 0 zinc-ribbon family FAD_binding_1 PF00667.20 EOO03685.1 - 1.7e-66 224.0 0.0 2.9e-66 223.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EOO03685.1 - 2e-09 38.1 0.0 5.8e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 EOO03685.1 - 1.6e-08 34.9 0.0 4e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 EOO03685.1 - 1.5e-06 28.4 0.1 5.7e-06 26.6 0.1 2.1 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Osmo_MPGsynth PF09488.10 EOO03686.1 - 3.8e-141 470.3 0.0 4.3e-141 470.1 0.0 1.0 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Glycos_transf_2 PF00535.26 EOO03686.1 - 0.00022 21.1 0.5 0.34 10.7 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 2 DUF3295 PF11702.8 EOO03687.1 - 2.1e-176 588.2 31.1 2.6e-176 587.9 31.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 EOO03687.1 - 2.6e-11 43.2 2.4 4.2e-11 42.5 1.2 2.0 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) MCPVI PF02993.14 EOO03687.1 - 0.006 16.4 5.2 0.016 15.0 5.2 1.9 1 0 0 1 1 1 1 Minor capsid protein VI DCB PF16213.5 EOO03688.1 - 0.0011 18.6 1.2 0.0019 17.9 0.5 1.6 1 1 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 DAO PF01266.24 EOO03690.1 - 4.2e-44 151.6 1.8 5.3e-44 151.2 1.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EOO03690.1 - 1.2e-08 35.1 0.5 0.0021 18.0 0.3 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EOO03690.1 - 5.6e-07 29.0 0.2 0.00046 19.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 EOO03690.1 - 5.3e-06 25.8 0.0 5.1e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EOO03690.1 - 6.8e-06 25.5 0.0 0.0085 15.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EOO03690.1 - 5.6e-05 23.3 0.0 0.00025 21.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 EOO03690.1 - 0.0029 17.9 0.0 0.0055 17.0 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Lycopene_cycl PF05834.12 EOO03690.1 - 0.0057 15.8 0.1 0.058 12.4 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 EOO03690.1 - 0.027 13.7 0.2 0.095 11.9 0.0 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 EOO03690.1 - 0.047 12.9 0.0 2.6 7.2 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 EOO03690.1 - 0.13 12.8 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Phage_holin_2_4 PF16082.5 EOO03691.1 - 0.0042 16.8 0.9 0.0063 16.2 0.3 1.6 2 0 0 2 2 2 1 Bacteriophage holin family, superfamily II-like RAG1 PF12940.7 EOO03691.1 - 0.059 11.4 0.0 0.061 11.4 0.0 1.0 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase VHS PF00790.19 EOO03692.1 - 5.6e-26 91.1 0.0 1.1e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EOO03692.1 - 1.2e-07 31.9 0.4 3.2e-07 30.6 0.4 1.7 1 0 0 1 1 1 1 GAT domain SR-25 PF10500.9 EOO03692.1 - 0.028 14.0 10.9 0.047 13.3 10.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein 2OG-FeII_Oxy PF03171.20 EOO03693.1 - 4.5e-18 65.6 0.0 6.4e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 EOO03694.1 - 1.4e-24 86.6 0.1 2.9e-24 85.5 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain NTP_transf_2 PF01909.23 EOO03694.1 - 0.038 14.3 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain DHDPS PF00701.22 EOO03695.1 - 2.4e-36 125.0 0.0 3e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Smr PF01713.21 EOO03695.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Smr domain Toxin_ToxA PF11584.8 EOO03695.1 - 0.16 12.0 0.2 0.55 10.2 0.0 1.9 2 1 1 3 3 3 0 Proteinaceous host-selective toxin ToxA Usp PF00582.26 EOO03698.1 - 2.5e-24 86.4 4.9 1.1e-15 58.3 1.0 3.0 3 0 0 3 3 3 2 Universal stress protein family zf-C2H2_2 PF12756.7 EOO03699.1 - 5.2e-31 107.0 6.5 1.7e-29 102.1 1.0 3.0 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EOO03699.1 - 9.3e-07 29.0 4.8 3.6e-06 27.2 4.8 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EOO03699.1 - 9.5e-05 22.6 7.1 9.5e-05 22.6 7.1 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EOO03699.1 - 0.0021 18.8 10.3 0.62 11.0 0.5 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EOO03699.1 - 0.4 11.2 11.4 1.3 9.6 1.2 3.6 3 1 0 3 3 3 0 Zinc finger, C2H2 type TBP PF00352.21 EOO03700.1 - 1.6e-67 223.5 0.1 7.4e-33 112.4 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EOO03700.1 - 0.00012 22.1 0.0 0.23 11.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EOO03700.1 - 0.13 12.1 0.1 0.7 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) RTA1 PF04479.13 EOO03701.1 - 1.4e-49 168.6 8.7 1.7e-49 168.3 8.7 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF1600 PF07667.11 EOO03701.1 - 0.0072 16.5 0.2 0.0072 16.5 0.2 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1600) Glyco_hydro_16 PF00722.21 EOO03703.1 - 1.5e-44 151.5 2.5 1.5e-44 151.5 2.5 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 FSA_C PF10479.9 EOO03703.1 - 1.6 6.8 17.3 3 5.9 17.3 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SOG2 PF10428.9 EOO03703.1 - 8.4 5.5 15.8 12 5.0 15.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4474 PF14751.6 EOO03704.1 - 0.15 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4474) LURAP PF14854.6 EOO03705.1 - 0.008 16.1 5.4 0.0085 16.0 1.9 2.4 1 1 1 2 2 2 1 Leucine rich adaptor protein DUF3473 PF11959.8 EOO03705.1 - 0.061 13.4 0.8 5.6 7.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3473) HECT PF00632.25 EOO03706.1 - 9.5e-67 225.6 0.0 1.4e-66 225.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF2838 PF10998.8 EOO03706.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) E1-E2_ATPase PF00122.20 EOO03707.1 - 2.7e-50 170.4 0.1 7.4e-50 169.0 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EOO03707.1 - 8.4e-34 117.7 0.6 2.4e-33 116.2 0.6 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EOO03707.1 - 9.6e-18 64.4 2.1 7.2e-11 42.4 0.2 3.1 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EOO03707.1 - 9.7e-06 25.5 0.4 4.1e-05 23.4 0.1 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EOO03707.1 - 5.5e-05 23.7 0.0 0.00012 22.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PCB_OB PF17092.5 EOO03707.1 - 0.0043 17.8 0.3 0.35 11.6 0.0 3.1 3 0 0 3 3 3 1 Penicillin-binding protein OB-like domain Importin_rep_3 PF18806.1 EOO03707.1 - 0.046 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Importin 13 repeat DUF2067 PF09840.9 EOO03707.1 - 0.087 12.4 0.0 5.9 6.4 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2067) VWA_3 PF13768.6 EOO03707.1 - 0.11 12.4 0.7 13 5.7 0.0 3.5 3 1 1 4 4 4 0 von Willebrand factor type A domain Aim21 PF11489.8 EOO03708.1 - 2e-192 642.0 92.6 2e-192 642.0 92.6 2.3 3 0 0 3 3 3 1 Altered inheritance of mitochondria protein 21 NMO PF03060.15 EOO03709.1 - 2.3e-55 188.3 0.2 2.2e-54 185.1 0.2 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EOO03709.1 - 2.5e-11 43.2 0.0 1.7e-09 37.1 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EOO03709.1 - 0.00088 18.4 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase TTL PF03133.15 EOO03710.1 - 1.1e-57 195.5 0.0 2e-57 194.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 EOO03710.1 - 3.8e-25 88.8 0.0 7e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 EOO03710.1 - 0.0034 16.7 0.0 0.013 14.7 0.0 1.9 3 0 0 3 3 3 1 YheC/D like ATP-grasp HSP70 PF00012.20 EOO03711.1 - 7.3e-266 883.1 15.3 8.3e-266 882.9 15.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EOO03711.1 - 6.8e-18 64.6 2.9 1.2e-16 60.4 0.7 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.10 EOO03711.1 - 0.0023 17.0 0.3 0.14 11.2 0.2 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 EOO03711.1 - 0.0039 17.6 6.4 3 8.3 0.5 3.8 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 EOO03711.1 - 0.026 13.8 2.3 0.17 11.1 0.1 2.7 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 EOO03711.1 - 0.049 13.1 0.5 1.6 8.2 0.1 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF3319 PF11782.8 EOO03711.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3319) HEPPP_synt_1 PF07307.11 EOO03711.1 - 0.13 11.8 1.4 0.27 10.8 1.4 1.5 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 DUF5300 PF17224.3 EOO03711.1 - 0.34 11.2 2.4 8.8 6.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5300) AAA_12 PF13087.6 EOO03712.1 - 5.8e-54 182.7 0.0 1.1e-53 181.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EOO03712.1 - 7.2e-35 121.0 1.9 6.6e-17 62.2 0.0 3.0 2 1 1 3 3 3 2 AAA domain Dna2 PF08696.11 EOO03712.1 - 8.6e-28 97.5 0.3 3.2e-27 95.7 0.0 2.1 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_30 PF13604.6 EOO03712.1 - 2.5e-14 53.5 0.0 5.5e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EOO03712.1 - 1.9e-13 51.0 0.0 4.9e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 EOO03712.1 - 8.8e-08 32.4 0.1 1.8e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 EOO03712.1 - 3e-07 30.4 0.3 0.13 11.9 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EOO03712.1 - 3e-05 24.0 0.0 0.00011 22.1 0.0 2.0 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 EOO03712.1 - 4.1e-05 23.3 0.1 8.1e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 EOO03712.1 - 0.0007 19.3 0.1 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 EOO03712.1 - 0.0052 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain PIF1 PF05970.14 EOO03712.1 - 0.0062 15.8 0.1 0.1 11.8 0.1 2.2 2 0 0 2 2 2 1 PIF1-like helicase AAA_7 PF12775.7 EOO03712.1 - 0.0065 16.0 0.1 0.015 14.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region cobW PF02492.19 EOO03712.1 - 0.0069 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.15 EOO03712.1 - 0.0095 16.0 0.1 0.027 14.5 0.1 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CbiA PF01656.23 EOO03712.1 - 0.013 15.5 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RuvB_N PF05496.12 EOO03712.1 - 0.016 15.0 0.1 0.04 13.7 0.1 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF87 PF01935.17 EOO03712.1 - 0.018 15.1 0.4 0.049 13.7 0.1 1.8 2 0 0 2 2 1 0 Helicase HerA, central domain DUF2075 PF09848.9 EOO03712.1 - 0.029 13.6 0.0 0.077 12.2 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 EOO03712.1 - 0.043 13.4 0.1 0.25 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EOO03712.1 - 0.055 13.5 0.1 0.17 11.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EOO03712.1 - 0.057 12.5 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.14 EOO03712.1 - 0.078 12.9 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PEPCK_ATP PF01293.20 EOO03712.1 - 0.095 11.4 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA PF00004.29 EOO03712.1 - 0.097 13.1 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EOO03712.1 - 0.14 12.0 0.1 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 EOO03712.1 - 0.16 12.5 0.0 0.44 11.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Pkinase PF00069.25 EOO03713.1 - 3.3e-71 239.7 0.0 4.4e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO03713.1 - 2.5e-46 158.1 0.0 4.2e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EOO03713.1 - 2.8e-17 62.8 0.1 9.9e-17 61.1 0.0 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 EOO03713.1 - 4.6e-08 32.7 0.0 8.8e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EOO03713.1 - 6.4e-07 28.5 0.0 1.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EOO03713.1 - 0.012 15.0 0.2 0.2 11.0 0.0 2.6 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EOO03713.1 - 0.014 14.4 0.1 0.014 14.4 0.1 1.8 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 EOO03713.1 - 0.12 12.3 2.7 0.26 11.2 0.0 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family DLH PF01738.18 EOO03714.1 - 1.6e-07 31.1 0.1 1.8e-07 30.9 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Cg6151-P PF10233.9 EOO03715.1 - 6.3e-43 145.7 13.4 7.4e-43 145.5 13.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P MPS-4 PF17523.2 EOO03715.1 - 0.23 11.6 3.3 0.51 10.5 3.3 1.7 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 DUF2207 PF09972.9 EOO03715.1 - 5 5.8 9.3 5.3 5.7 8.6 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) GET2 PF08690.10 EOO03716.1 - 3.3 7.3 8.2 1.3 8.6 5.9 1.6 1 1 1 2 2 2 0 GET complex subunit GET2 Ysc84 PF04366.12 EOO03717.1 - 2e-40 137.5 0.2 3.3e-40 136.8 0.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EOO03717.1 - 4.3e-14 51.8 0.2 1.8e-13 49.9 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EOO03717.1 - 3.5e-12 45.8 0.1 9.2e-12 44.5 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EOO03717.1 - 2.9e-11 43.1 0.0 5.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 EOO03717.1 - 0.025 14.3 0.1 0.05 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Aminotran_4 PF01063.19 EOO03718.1 - 1.7e-34 119.7 0.0 2.1e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV p450 PF00067.22 EOO03719.1 - 8.6e-28 97.3 0.0 2e-27 96.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 ARID PF01388.21 EOO03720.1 - 2.8e-16 60.0 0.0 8.3e-16 58.4 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 EOO03720.1 - 0.023 15.3 0.0 0.056 14.1 0.0 1.7 1 0 0 1 1 1 0 RFX DNA-binding domain KH_1 PF00013.29 EOO03721.1 - 3.1e-92 302.4 29.6 3e-13 49.4 0.3 13.7 13 1 0 13 13 13 10 KH domain SLS PF14611.6 EOO03721.1 - 8.9e-15 55.1 8.0 0.085 12.7 0.4 6.4 4 1 0 6 6 6 5 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 EOO03721.1 - 1.6e-12 47.1 25.1 0.021 14.6 0.1 8.2 8 0 0 8 8 8 4 KH domain KH_4 PF13083.6 EOO03721.1 - 0.0026 17.6 14.2 0.038 13.9 0.1 5.8 7 0 0 7 7 7 2 KH domain KH_5 PF13184.6 EOO03721.1 - 0.34 11.0 14.9 43 4.3 0.1 6.6 7 0 0 7 7 7 0 NusA-like KH domain NikR_C PF08753.11 EOO03721.1 - 0.62 10.3 1.9 11 6.3 0.0 3.5 4 0 0 4 4 4 0 NikR C terminal nickel binding domain zf-primase PF09329.11 EOO03722.1 - 1.1e-17 63.6 1.3 1.9e-17 62.8 1.3 1.4 1 0 0 1 1 1 1 Primase zinc finger TRI12 PF06609.13 EOO03723.1 - 0.009 14.5 1.6 0.26 9.6 0.2 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF1449 PF07290.11 EOO03723.1 - 0.016 14.9 2.1 0.023 14.3 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) MFS_1 PF07690.16 EOO03723.1 - 0.03 13.3 2.2 0.099 11.5 0.7 2.0 2 0 0 2 2 2 0 Major Facilitator Superfamily TPR_MLP1_2 PF07926.12 EOO03724.1 - 3.2e-37 127.5 29.6 3.2e-37 127.5 29.6 19.5 7 5 11 19 19 19 5 TPR/MLP1/MLP2-like protein PKcGMP_CC PF16808.5 EOO03724.1 - 0.054 13.4 0.2 0.054 13.4 0.2 12.1 13 2 1 14 14 14 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PurL_C PF16904.5 EOO03724.1 - 0.34 11.2 5.4 1.7 9.0 0.3 3.5 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine synthase II C-terminus zf-C3HC PF07967.13 EOO03725.1 - 2.4e-44 150.6 0.4 3.5e-39 133.9 0.3 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 EOO03725.1 - 1.5e-27 95.6 0.6 7.4e-27 93.4 0.0 2.3 2 0 0 2 2 2 1 Rsm1-like BIR PF00653.21 EOO03725.1 - 0.0022 18.6 0.1 0.059 14.0 0.2 2.4 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain Imm53 PF15580.6 EOO03725.1 - 0.067 12.9 0.1 0.49 10.1 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 53 GTP_EFTU PF00009.27 EOO03726.1 - 2.3e-47 161.0 0.0 4.6e-47 160.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 EOO03726.1 - 3.6e-24 84.9 0.7 8.8e-24 83.6 0.7 1.7 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 EOO03726.1 - 1.4e-08 34.8 0.0 0.0002 21.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 EOO03726.1 - 2.2e-08 34.4 3.2 6.3e-08 32.9 0.1 2.7 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EOO03726.1 - 9.5e-07 29.1 0.1 2.9e-06 27.6 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Roc PF08477.13 EOO03726.1 - 0.00054 20.2 0.0 0.073 13.3 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EOO03726.1 - 0.01 15.3 0.0 0.75 9.2 0.0 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.19 EOO03726.1 - 0.019 14.5 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 EOO03726.1 - 0.09 12.3 0.1 2.1 7.9 0.0 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.18 EOO03726.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Septin Arf PF00025.21 EOO03726.1 - 0.17 11.3 2.1 6.2 6.2 0.1 2.7 2 1 1 3 3 3 0 ADP-ribosylation factor family G-alpha PF00503.20 EOO03726.1 - 0.28 10.3 1.0 2.2 7.3 0.1 2.3 2 1 1 3 3 3 0 G-protein alpha subunit Glyco_hydro_92 PF07971.12 EOO03727.1 - 4.3e-143 477.6 3.4 5.9e-143 477.1 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF2461 PF09365.10 EOO03727.1 - 1.8e-81 273.1 0.1 2.6e-81 272.5 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Glyco_hydro_92N PF17678.1 EOO03727.1 - 1.8e-06 28.0 0.0 3.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain NOA36 PF06524.12 EOO03727.1 - 0.64 9.3 18.3 1.1 8.5 18.3 1.3 1 0 0 1 1 1 0 NOA36 protein adh_short_C2 PF13561.6 EOO03728.1 - 2e-62 210.8 1.0 2.6e-62 210.5 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO03728.1 - 8.3e-52 175.5 1.1 1.1e-51 175.1 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO03728.1 - 1.8e-10 41.0 0.2 2.5e-10 40.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO03728.1 - 7.8e-05 22.3 0.3 0.00018 21.0 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.22 EOO03728.1 - 0.00087 19.3 0.4 0.0027 17.7 0.2 1.9 2 0 0 2 2 2 1 PA domain GDP_Man_Dehyd PF16363.5 EOO03728.1 - 0.0037 16.7 0.1 0.0061 16.0 0.1 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EOO03728.1 - 0.012 14.7 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 EOO03728.1 - 0.16 12.7 0.1 0.34 11.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain SelR PF01641.18 EOO03729.1 - 1.9e-49 166.7 0.1 2.9e-49 166.2 0.1 1.2 1 0 0 1 1 1 1 SelR domain MCM_OB PF17207.3 EOO03729.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 MCM OB domain RNase_H2-Ydr279 PF09468.10 EOO03730.1 - 9.1e-50 169.0 1.6 3.4e-49 167.1 0.4 2.2 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EOO03730.1 - 1.7e-22 79.5 0.1 4.2e-22 78.2 0.1 1.8 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain SVIP PF15811.5 EOO03730.1 - 0.11 13.0 7.6 0.26 11.8 7.6 1.6 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Pkinase PF00069.25 EOO03731.1 - 1.4e-07 31.2 0.0 1.5e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO03731.1 - 2.6e-07 30.2 0.0 3.4e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.16 EOO03732.1 - 5.5e-23 81.5 23.7 5.5e-23 81.5 23.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_16 PF10294.9 EOO03733.1 - 1.9e-10 40.7 0.0 3.1e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EOO03733.1 - 0.0023 17.4 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 EOO03733.1 - 0.0053 16.1 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G SpoIIIAH PF12685.7 EOO03733.1 - 0.024 14.5 0.4 0.042 13.7 0.4 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Glyco_hydro_125 PF06824.11 EOO03734.1 - 1.5e-136 455.6 0.0 1.1e-96 324.3 0.0 2.0 1 1 1 2 2 2 2 Metal-independent alpha-mannosidase (GH125) Seipin PF06775.14 EOO03735.1 - 1.9e-61 207.6 1.1 2.5e-61 207.3 1.1 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) PhyH PF05721.13 EOO03736.1 - 1.7e-09 38.3 0.1 5.9e-09 36.5 0.1 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RRM_1 PF00076.22 EOO03737.1 - 1.3e-83 274.8 6.4 6.6e-23 80.3 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EOO03737.1 - 7.9e-29 99.6 4.2 8.5e-29 99.6 2.0 2.2 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 EOO03737.1 - 3e-08 33.4 0.2 0.00024 20.9 0.0 4.2 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EOO03737.1 - 1.9e-06 27.9 0.9 0.77 9.9 0.0 5.2 4 1 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EOO03737.1 - 0.00045 20.2 2.8 13 5.9 0.0 4.5 4 1 0 4 4 4 2 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.8 EOO03737.1 - 0.0024 18.0 0.0 8.9 6.5 0.0 3.8 3 0 0 3 3 3 1 Cobalamin biosynthesis central region YflT PF11181.8 EOO03737.1 - 0.011 16.2 8.3 0.11 13.0 0.7 3.4 3 0 0 3 3 3 0 Heat induced stress protein YflT Limkain-b1 PF11608.8 EOO03737.1 - 0.02 15.0 1.1 10 6.2 0.1 3.4 3 0 0 3 3 3 0 Limkain b1 OB_RNB PF08206.11 EOO03737.1 - 0.091 12.5 1.7 13 5.6 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Glyco_hydro_61 PF03443.14 EOO03738.1 - 4.2e-42 144.4 0.0 5e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 EOO03739.1 - 6.9e-15 54.8 14.4 8.3e-15 54.6 14.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EOO03739.1 - 1.8e-05 23.8 6.0 0.0097 14.8 3.9 2.0 2 0 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 EOO03739.1 - 0.0009 18.2 4.0 0.0009 18.2 4.0 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EOO03739.1 - 0.41 8.9 3.6 6.5 4.9 2.0 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DEAD PF00270.29 EOO03740.1 - 8.6e-46 155.9 0.1 3.4e-45 154.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EOO03740.1 - 9.8e-28 96.7 0.2 6.2e-27 94.1 0.0 2.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO03740.1 - 4.8e-06 26.7 0.0 7.8e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EOO03740.1 - 0.11 12.8 0.0 0.35 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain CM_2 PF01817.21 EOO03740.1 - 0.29 11.5 2.7 14 6.1 0.1 3.1 4 0 0 4 4 4 0 Chorismate mutase type II SIR2 PF02146.17 EOO03741.1 - 5.5e-61 205.6 0.0 1.4e-60 204.3 0.0 1.7 2 0 0 2 2 2 1 Sir2 family TPP_enzyme_M PF00205.22 EOO03741.1 - 0.00074 19.3 0.0 0.67 9.7 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 EOO03741.1 - 0.0019 18.0 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) Med16 PF11635.8 EOO03741.1 - 0.15 9.9 0.0 0.22 9.4 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 Ribosomal_S7 PF00177.21 EOO03742.1 - 1.5e-25 89.6 0.0 2e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e NTF2 PF02136.20 EOO03744.1 - 6.4e-30 104.2 0.0 7.1e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Peptidase_C11 PF03415.14 EOO03744.1 - 0.039 13.4 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 Clostripain family DUF4518 PF15008.6 EOO03744.1 - 0.042 13.0 0.0 0.22 10.7 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) DUF4440 PF14534.6 EOO03744.1 - 0.17 12.3 0.0 0.2 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) HECT PF00632.25 EOO03745.1 - 1.7e-80 270.8 0.0 3.3e-80 269.8 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 EOO03745.1 - 0.00099 18.7 0.9 0.0023 17.6 0.9 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif PSD5 PF07637.11 EOO03745.1 - 0.25 11.7 1.5 9.7 6.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1595) ETF_QO PF05187.13 EOO03746.1 - 7.2e-49 164.2 0.8 1.2e-48 163.5 0.8 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 EOO03746.1 - 8.4e-09 35.5 0.0 3.4e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EOO03746.1 - 8.7e-08 32.1 0.1 7.5e-05 22.5 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EOO03746.1 - 2.7e-05 23.5 0.0 7.7e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EOO03746.1 - 2.8e-05 23.5 0.0 0.0038 16.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EOO03746.1 - 6.3e-05 22.2 0.5 0.0042 16.2 0.7 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EOO03746.1 - 0.00024 19.9 0.3 0.00036 19.3 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 EOO03746.1 - 0.00064 19.2 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EOO03746.1 - 0.00082 18.7 0.1 0.0013 18.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EOO03746.1 - 0.002 18.1 0.2 0.0042 17.1 0.2 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EOO03746.1 - 0.0027 16.6 0.0 0.2 10.5 0.1 2.2 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 EOO03746.1 - 0.0085 15.4 0.2 0.013 14.8 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EOO03746.1 - 0.018 14.3 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fer4_7 PF12838.7 EOO03746.1 - 0.02 15.5 1.1 0.057 14.0 1.1 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Pyr_redox PF00070.27 EOO03746.1 - 0.045 14.3 0.0 5.3 7.7 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EOO03746.1 - 0.048 12.7 0.2 0.068 12.2 0.2 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.24 EOO03746.1 - 0.081 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GIDA PF01134.22 EOO03746.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_2 PF12797.7 EOO03746.1 - 0.14 12.3 0.7 0.38 10.9 0.7 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain FCH PF00611.23 EOO03747.1 - 3.1e-16 59.4 0.4 1.2e-15 57.5 0.1 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EOO03747.1 - 3.6e-13 48.9 0.0 7e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EOO03747.1 - 3.6e-11 42.7 0.0 8e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EOO03747.1 - 9.6e-11 41.2 0.0 9.7e-10 38.0 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain ApoLp-III PF07464.11 EOO03747.1 - 1.7 8.7 12.6 0.17 12.0 1.6 3.0 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Spc24 PF08286.11 EOO03747.1 - 5.2 7.4 6.3 2.8 8.2 0.5 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Beta-lactamase PF00144.24 EOO03748.1 - 3.2e-42 144.9 2.9 4e-42 144.6 2.3 1.4 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.8 EOO03748.1 - 7.7e-11 42.4 0.0 1.6e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) SIS PF01380.22 EOO03748.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 SIS domain Beta-lactamase2 PF13354.6 EOO03748.1 - 0.18 11.4 0.0 1.6 8.3 0.0 2.2 1 1 1 2 2 2 0 Beta-lactamase enzyme family ESSS PF10183.9 EOO03749.1 - 3.7e-19 68.9 0.0 4.4e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Cpn60_TCP1 PF00118.24 EOO03750.1 - 3.5e-158 527.3 6.4 4e-158 527.1 6.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 EOO03750.1 - 0.1 12.7 2.2 5.4 7.2 0.1 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain Fip1 PF05182.13 EOO03751.1 - 1.4e-20 72.5 1.0 2.5e-20 71.7 1.0 1.4 1 0 0 1 1 1 1 Fip1 motif Abhydrolase_1 PF00561.20 EOO03752.1 - 1.1e-21 77.7 0.0 2.5e-21 76.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EOO03752.1 - 3.7e-16 59.1 0.0 5.4e-15 55.3 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EOO03752.1 - 9.1e-13 49.3 0.0 7.6e-12 46.3 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 EOO03752.1 - 6.8e-06 25.6 0.0 1.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 EOO03752.1 - 0.00035 20.3 0.0 0.00087 19.0 0.0 1.7 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 EOO03752.1 - 0.005 16.7 0.0 0.16 11.8 0.0 2.8 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 EOO03752.1 - 0.013 15.1 0.0 0.045 13.3 0.0 1.8 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 EOO03752.1 - 0.041 13.6 0.0 0.099 12.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EOO03752.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) FAM176 PF14851.6 EOO03752.1 - 0.091 12.4 1.9 0.27 10.9 1.9 1.7 1 0 0 1 1 1 0 FAM176 family Thioesterase PF00975.20 EOO03752.1 - 0.11 12.6 3.1 0.2 11.8 0.2 2.8 2 1 0 2 2 2 0 Thioesterase domain Chlorophyllase2 PF12740.7 EOO03752.1 - 0.16 10.9 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 EOO03752.1 - 0.21 11.3 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF2956 PF11169.8 EOO03752.1 - 2 8.6 6.1 1.2 9.4 3.4 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF2956) PBP1_TM PF14812.6 EOO03752.1 - 2.7 8.4 6.9 7.7 7.0 3.6 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal KCNQ2_u3 PF16642.5 EOO03752.1 - 5.7 8.0 9.4 5.8 8.0 3.4 2.4 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 DUF5427 PF10310.9 EOO03752.1 - 8 5.3 10.9 1.1 8.1 5.6 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5427) UDPGT PF00201.18 EOO03753.1 - 2.2e-05 23.5 0.0 3.2e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PAP_assoc PF03828.19 EOO03754.1 - 1.9e-16 60.0 0.1 1.2e-10 41.4 0.0 2.5 2 0 0 2 2 2 2 Cid1 family poly A polymerase Anp1 PF03452.14 EOO03755.1 - 9.7e-114 379.2 1.2 7.2e-113 376.4 0.0 2.0 2 0 0 2 2 2 1 Anp1 FAO_M PF16350.5 EOO03755.1 - 0.055 13.8 0.2 0.18 12.2 0.2 1.9 1 0 0 1 1 1 0 FAD dependent oxidoreductase central domain Vps36_ESCRT-II PF11605.8 EOO03756.1 - 0.07 13.3 0.0 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 Sugar_tr PF00083.24 EOO03757.1 - 1.2e-35 123.3 21.0 8.4e-35 120.5 21.0 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO03757.1 - 3.1e-30 105.3 49.2 9.8e-27 93.8 31.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.24 EOO03758.1 - 1.1e-24 87.7 0.0 1.2e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase UMP1 PF05348.11 EOO03759.1 - 1.2e-40 138.4 0.0 1.4e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Sugar_tr PF00083.24 EOO03760.1 - 1.9e-50 172.1 2.4 2.4e-50 171.7 2.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO03760.1 - 1.9e-16 59.9 9.8 2.5e-16 59.6 9.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EOO03760.1 - 0.00011 20.8 1.4 0.00017 20.2 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Aminotran_1_2 PF00155.21 EOO03762.1 - 2.5e-88 296.7 0.0 2.9e-88 296.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF5038 PF16441.5 EOO03762.1 - 0.096 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5038) PKD_channel PF08016.12 EOO03763.1 - 1.9e-05 23.6 16.8 2.4e-05 23.2 11.9 2.3 2 0 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 EOO03763.1 - 0.00078 18.7 22.1 0.0093 15.2 22.1 2.1 1 1 0 1 1 1 1 Ion transport protein Seryl_tRNA_N PF02403.22 EOO03763.1 - 0.04 14.2 0.4 0.075 13.3 0.4 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 EOO03763.1 - 0.16 11.8 0.2 0.38 10.6 0.2 1.6 1 0 0 1 1 1 0 Septum formation initiator Sulfatase PF00884.23 EOO03765.1 - 1.3e-63 215.3 0.3 1.6e-63 214.9 0.3 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 EOO03765.1 - 2.8e-20 72.5 4.1 1.7e-19 70.0 4.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 EOO03765.1 - 1.5e-06 28.1 0.9 0.0045 16.6 0.0 2.5 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EOO03765.1 - 0.047 12.3 0.0 0.097 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF229) E1-E2_ATPase PF00122.20 EOO03766.1 - 1.1e-17 64.1 0.0 3.2e-17 62.6 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EOO03766.1 - 2.1e-12 47.8 8.5 1e-07 32.5 5.2 3.5 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EOO03766.1 - 0.0013 18.5 0.1 0.025 14.3 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EOO03766.1 - 0.0077 16.3 0.0 0.032 14.3 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) DUF4059 PF13268.6 EOO03766.1 - 0.078 13.4 1.1 10 6.6 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) S6PP PF05116.13 EOO03766.1 - 0.19 11.2 0.4 3.8 7.0 0.0 2.7 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase MFS_1 PF07690.16 EOO03768.1 - 6.6e-40 137.1 23.0 6.6e-40 137.1 23.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO03768.1 - 4.3e-11 42.4 2.7 4.3e-11 42.4 2.7 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EOO03768.1 - 4.2e-07 28.8 1.1 6.4e-07 28.2 1.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2722 PF10846.8 EOO03769.1 - 0.0043 16.1 0.8 0.0043 16.1 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Adeno_E3 PF06040.11 EOO03769.1 - 0.088 13.0 0.2 0.13 12.5 0.2 1.2 1 0 0 1 1 1 0 Adenovirus E3 protein MRP-L28 PF09812.9 EOO03771.1 - 9.6e-08 32.3 0.9 1.2e-07 32.0 0.9 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 PGC7_Stella PF15549.6 EOO03771.1 - 0.0097 15.9 5.4 0.014 15.4 5.4 1.2 1 0 0 1 1 1 1 PGC7/Stella/Dppa3 domain Syntaxin-18_N PF10496.9 EOO03772.1 - 1.4e-10 41.3 2.4 5.8e-09 36.1 0.3 2.8 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 EOO03772.1 - 0.00079 19.4 0.0 0.0036 17.2 0.0 2.2 2 0 0 2 2 2 1 SNARE domain TraT PF05818.12 EOO03772.1 - 0.28 10.8 4.1 6.9 6.3 0.7 2.2 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein DUF16 PF01519.16 EOO03772.1 - 1.8 9.1 5.9 0.78 10.3 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 HIT PF01230.23 EOO03773.1 - 1.4e-21 77.0 0.0 2.9e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EOO03773.1 - 0.00092 19.7 0.0 2 8.9 0.0 2.2 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding FAD_binding_3 PF01494.19 EOO03774.1 - 4.2e-13 49.3 0.0 1.4e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EOO03774.1 - 0.016 15.4 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 EOO03774.1 - 0.023 13.7 0.0 0.039 13.0 0.0 1.4 1 1 0 1 1 1 0 Squalene epoxidase CENP-C_C PF11699.8 EOO03775.1 - 0.15 12.2 0.2 1.9 8.8 0.0 2.0 2 0 0 2 2 2 0 Mif2/CENP-C like Sulfotransfer_4 PF17784.1 EOO03776.1 - 3.2e-45 154.6 0.0 4e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain AA_permease PF00324.21 EOO03777.1 - 8.9e-131 436.8 48.0 1.1e-130 436.5 48.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EOO03777.1 - 2.8e-32 112.1 53.0 3.8e-32 111.7 53.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF383 PF04063.14 EOO03778.1 - 1.2e-67 227.3 0.1 1e-66 224.3 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EOO03778.1 - 2.4e-23 81.7 2.8 9.7e-23 79.8 2.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF384) BESS PF02944.20 EOO03778.1 - 0.12 12.2 2.1 0.29 11.0 2.1 1.7 1 0 0 1 1 1 0 BESS motif MFS_1 PF07690.16 EOO03779.1 - 2.5e-27 95.7 0.1 2.5e-27 95.7 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO03779.1 - 7.7e-10 38.2 3.0 1.1e-09 37.7 3.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_5 PF05631.14 EOO03779.1 - 0.0013 17.8 0.3 0.0018 17.3 0.3 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 EOO03779.1 - 0.0017 17.3 4.6 0.015 14.2 3.0 2.3 2 0 0 2 2 2 1 MFS_1 like family MFS_4 PF06779.14 EOO03779.1 - 0.0089 15.4 1.4 0.013 14.8 1.4 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB NIR_SIR PF01077.22 EOO03780.1 - 1.4e-54 183.9 0.0 9.7e-50 168.2 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EOO03780.1 - 6.9e-31 105.9 0.0 2.7e-15 56.0 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EOO03780.1 - 1.7e-29 102.9 0.0 3.9e-29 101.7 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 EOO03780.1 - 1.8e-08 34.4 0.2 5.6e-08 32.8 0.1 1.8 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg RHH_7 PF16777.5 EOO03780.1 - 0.026 14.9 0.0 0.085 13.3 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator, RHH-like, CopG Mito_carr PF00153.27 EOO03781.1 - 3.7e-56 187.1 3.8 1.2e-18 66.8 0.1 4.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EOO03781.1 - 0.0037 16.5 0.0 0.8 8.8 0.0 2.4 2 0 0 2 2 2 2 Gammaproteobacterial serine protease Mito_carr PF00153.27 EOO03783.1 - 2.3e-42 142.8 10.1 8.4e-17 60.9 0.2 3.6 4 0 0 4 4 4 3 Mitochondrial carrier protein MFS_1 PF07690.16 EOO03784.1 - 3.4e-32 111.7 18.1 4.1e-32 111.5 18.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily HgmA PF04209.13 EOO03785.1 - 2.2e-38 132.1 0.1 2.6e-38 131.8 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase HLH PF00010.26 EOO03786.1 - 7.1e-13 48.3 0.8 7.1e-13 48.3 0.8 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CDC27 PF09507.10 EOO03786.1 - 0.13 11.6 23.5 0.17 11.3 23.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PPP4R2 PF09184.11 EOO03786.1 - 2.2 7.8 13.8 3.4 7.2 13.8 1.4 1 0 0 1 1 1 0 PPP4R2 Ndc1_Nup PF09531.10 EOO03786.1 - 3.2 6.3 11.4 3.8 6.1 11.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPR_14 PF13428.6 EOO03787.1 - 1.4e-13 50.4 17.0 2 9.4 0.0 11.2 10 2 2 12 12 12 3 Tetratricopeptide repeat Suf PF05843.14 EOO03787.1 - 2.6e-11 44.1 6.6 0.039 13.9 0.0 6.5 3 2 3 6 6 6 3 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 EOO03787.1 - 3.8e-08 33.4 6.3 0.28 11.1 0.1 6.4 6 0 0 6 6 6 3 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 EOO03787.1 - 1.1e-07 31.5 3.8 0.11 12.8 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EOO03787.1 - 1.4e-05 25.3 5.8 1.2 9.5 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 EOO03787.1 - 0.00043 19.6 10.4 0.00065 19.0 0.5 3.9 4 1 1 5 5 5 2 Tetratricopeptide repeat RPN7 PF10602.9 EOO03787.1 - 0.0006 19.6 0.1 0.0036 17.0 0.2 2.4 2 1 0 2 2 2 1 26S proteasome subunit RPN7 TPR_2 PF07719.17 EOO03787.1 - 0.077 13.1 20.3 9.9 6.6 0.0 7.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_4 PF07721.14 EOO03787.1 - 0.12 13.0 0.2 9.3 7.2 0.0 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat Pol_alpha_B_N PF08418.10 EOO03787.1 - 0.18 11.8 0.2 0.31 11.0 0.2 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal MIT PF04212.18 EOO03787.1 - 0.24 11.5 1.9 0.73 9.9 0.1 2.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain NRDE-2 PF08424.10 EOO03787.1 - 0.42 9.7 16.4 0.18 10.9 0.2 6.2 4 2 3 7 7 7 0 NRDE-2, necessary for RNA interference TPR_10 PF13374.6 EOO03787.1 - 0.5 10.3 11.7 48 4.0 0.1 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 EOO03787.1 - 2.2 8.9 7.7 61 4.3 0.0 6.3 8 0 0 8 8 7 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 EOO03788.1 - 5.8e-69 232.5 0.0 7.2e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Lipoprotein_Ltp PF07553.11 EOO03788.1 - 0.093 13.0 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Host cell surface-exposed lipoprotein SNF5 PF04855.12 EOO03789.1 - 8.6e-95 317.0 0.0 1.1e-94 316.7 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 EOO03789.1 - 7.3e-06 25.5 1.3 1.9e-05 24.2 1.3 1.8 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 EOO03789.1 - 0.013 15.2 5.7 0.17 11.7 1.5 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain 2-oxoacid_dh PF00198.23 EOO03790.1 - 7.1e-75 251.4 0.1 9.7e-75 251.0 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EOO03790.1 - 4.3e-19 68.1 0.9 8.8e-19 67.1 0.9 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EOO03790.1 - 5e-09 36.4 0.9 1.3e-08 35.1 0.9 1.7 1 0 0 1 1 1 1 e3 binding domain TFIIF_alpha PF05793.12 EOO03790.1 - 0.19 10.3 4.4 0.28 9.7 4.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PP2C_2 PF13672.6 EOO03791.1 - 0.046 13.4 0.9 0.059 13.0 0.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2C 4HBT PF03061.22 EOO03792.1 - 7.3e-12 45.5 0.0 9.1e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase superfamily IML1 PF12257.8 EOO03793.1 - 5.2e-103 344.1 0.0 1.2e-102 342.9 0.0 1.6 1 1 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 ABC_tran PF00005.27 EOO03794.1 - 7.8e-47 159.2 0.0 7.4e-24 84.8 0.0 3.6 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 EOO03794.1 - 1.1e-25 89.4 1.4 2.7e-25 88.2 0.0 2.5 3 0 0 3 3 1 1 Four helical bundle domain AAA_21 PF13304.6 EOO03794.1 - 2.9e-17 63.4 0.0 0.0019 18.1 0.0 5.1 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EOO03794.1 - 4.2e-17 62.3 0.1 2.4e-05 23.9 0.0 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EOO03794.1 - 5.1e-09 35.7 0.0 0.0048 16.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EOO03794.1 - 1.7e-08 34.5 0.1 0.0004 20.3 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EOO03794.1 - 1.9e-08 35.1 10.7 0.00011 22.8 0.1 3.5 4 0 0 4 4 2 2 AAA domain MMR_HSR1 PF01926.23 EOO03794.1 - 1.3e-07 31.7 0.0 0.0016 18.5 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EOO03794.1 - 3.6e-07 30.5 0.0 0.017 15.4 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.6 EOO03794.1 - 1.6e-06 28.5 0.1 0.032 14.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EOO03794.1 - 7.7e-06 26.5 0.0 0.17 12.4 0.0 3.3 3 0 0 3 3 2 2 AAA domain Dynamin_N PF00350.23 EOO03794.1 - 1.4e-05 25.2 0.0 0.0012 18.9 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 EOO03794.1 - 2.8e-05 24.6 0.3 0.27 11.6 0.0 3.7 5 0 0 5 5 2 2 AAA ATPase domain AAA_33 PF13671.6 EOO03794.1 - 3e-05 24.2 0.0 0.47 10.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 EOO03794.1 - 3.6e-05 22.9 0.6 0.36 9.8 0.0 3.1 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 EOO03794.1 - 4.1e-05 23.5 2.5 0.076 12.7 0.0 3.6 5 0 0 5 5 3 2 AAA ATPase domain PduV-EutP PF10662.9 EOO03794.1 - 0.0001 22.1 0.0 0.069 12.9 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 EOO03794.1 - 0.00012 22.4 0.0 0.96 9.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA PF00004.29 EOO03794.1 - 0.00015 22.2 0.0 0.52 10.7 0.0 3.7 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 EOO03794.1 - 0.00019 21.1 0.0 0.14 11.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EOO03794.1 - 0.00049 20.1 0.0 0.49 10.3 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 EOO03794.1 - 0.00052 20.0 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 EOO03794.1 - 0.00079 19.6 0.5 0.88 9.6 0.0 3.8 4 0 0 4 4 3 1 Helicase HerA, central domain AAA_24 PF13479.6 EOO03794.1 - 0.00093 19.0 0.0 1.6 8.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain G-alpha PF00503.20 EOO03794.1 - 0.00093 18.4 0.0 1.1 8.4 0.0 2.8 3 0 0 3 3 3 2 G-protein alpha subunit AAA_30 PF13604.6 EOO03794.1 - 0.0014 18.4 0.0 3.3 7.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 EOO03794.1 - 0.0022 18.0 0.0 4.5 7.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 EOO03794.1 - 0.0045 16.6 0.0 4.3 6.9 0.0 3.1 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain HEAT PF02985.22 EOO03794.1 - 0.0047 17.1 0.4 52 4.5 0.0 4.5 4 0 0 4 4 3 0 HEAT repeat SbcCD_C PF13558.6 EOO03794.1 - 0.0052 17.0 0.0 1.1 9.5 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 EOO03794.1 - 0.0059 15.8 0.1 0.29 10.3 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain ParcG PF10274.9 EOO03794.1 - 0.0067 16.6 0.6 10 6.2 0.1 3.2 1 1 1 3 3 3 0 Parkin co-regulated protein PRK PF00485.18 EOO03794.1 - 0.0068 16.2 0.0 0.45 10.2 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_13 PF13166.6 EOO03794.1 - 0.0093 14.7 0.9 2.7 6.5 0.0 3.5 3 1 0 3 3 3 1 AAA domain Roc PF08477.13 EOO03794.1 - 0.01 16.0 0.0 8.5 6.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CLP1_P PF16575.5 EOO03794.1 - 0.011 15.6 0.0 0.81 9.5 0.0 2.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP_bind_1 PF03029.17 EOO03794.1 - 0.013 15.2 0.0 7.8 6.2 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 EOO03794.1 - 0.014 14.7 0.1 2.5 7.3 0.0 2.8 3 0 0 3 3 3 0 Septin ATPase_2 PF01637.18 EOO03794.1 - 0.015 15.2 0.0 3.4 7.5 0.0 3.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EOO03794.1 - 0.022 14.2 0.0 4.6 6.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EOO03794.1 - 0.023 14.5 0.0 5.7 6.6 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 EOO03794.1 - 0.026 14.2 0.7 6 6.5 0.0 2.7 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Ploopntkinase3 PF18751.1 EOO03794.1 - 0.032 14.1 0.0 8.9 6.2 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 T2SSE PF00437.20 EOO03794.1 - 0.044 12.8 0.1 3.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 EOO03794.1 - 0.045 13.5 0.0 9.9 5.8 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase NTPase_1 PF03266.15 EOO03794.1 - 0.056 13.4 0.1 13 5.6 0.0 2.8 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 EOO03794.1 - 0.071 12.5 0.0 4.6 6.6 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EOO03794.1 - 0.086 12.4 0.0 8 6.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EOO03794.1 - 0.1 11.7 0.0 11 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FeoB_N PF02421.18 EOO03794.1 - 0.11 12.0 0.2 1.1 8.7 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B dNK PF01712.19 EOO03794.1 - 0.11 12.3 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase Dopey_N PF04118.14 EOO03794.1 - 0.14 11.2 0.0 0.47 9.5 0.0 1.9 2 0 0 2 2 1 0 Dopey, N-terminal ADH_zinc_N PF00107.26 EOO03795.1 - 2.3e-08 34.1 0.0 4.8e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HMG-CoA_red PF00368.18 EOO03795.1 - 0.0016 17.5 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase ADH_N PF08240.12 EOO03795.1 - 0.0066 16.3 0.0 0.018 14.9 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EOO03795.1 - 0.014 14.7 0.6 0.021 14.1 0.6 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.18 EOO03796.1 - 1.3e-27 96.5 0.0 1.8e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EOO03796.1 - 5.2e-09 36.1 10.7 8e-09 35.5 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ku PF02735.16 EOO03797.1 - 1.8e-46 158.4 0.0 3.9e-46 157.3 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EOO03797.1 - 1.7e-35 122.7 0.0 2.9e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EOO03797.1 - 7.2e-27 93.9 2.4 7.2e-27 93.9 2.4 2.1 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 EOO03797.1 - 1.7e-10 40.4 0.5 5.8e-10 38.7 0.3 2.1 2 0 0 2 2 2 1 SAP domain HeH PF12949.7 EOO03797.1 - 0.0033 17.1 0.5 0.012 15.3 0.5 2.1 1 0 0 1 1 1 1 HeH/LEM domain VWA_2 PF13519.6 EOO03797.1 - 0.056 14.1 0.1 0.83 10.3 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain DIMCO_N PF16844.5 EOO03797.1 - 0.14 12.5 1.5 0.34 11.3 0.6 2.1 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Tti2 PF10521.9 EOO03798.1 - 1.4e-78 264.3 0.0 1.9e-78 263.8 0.0 1.2 1 0 0 1 1 1 1 Tti2 family PolyA_pol PF01743.20 EOO03798.1 - 7.1e-25 87.9 0.0 1.3e-24 87.0 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EOO03798.1 - 1.1e-06 28.2 0.0 4.6e-06 26.3 0.0 2.1 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 EOO03798.1 - 0.0047 16.9 0.1 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative MHYT PF03707.16 EOO03799.1 - 2 8.6 6.1 19 5.5 0.4 3.4 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat Ras PF00071.22 EOO03800.1 - 1.2e-49 168.0 0.0 1.4e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EOO03800.1 - 4.5e-22 78.5 0.0 6e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EOO03800.1 - 8.3e-07 28.6 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EOO03800.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EOO03800.1 - 0.037 13.5 0.0 0.067 12.6 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EOO03800.1 - 0.15 11.8 0.0 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EOO03800.1 - 0.16 12.1 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 EOO03800.1 - 0.19 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MFS_1 PF07690.16 EOO03801.1 - 1.5e-38 132.6 9.4 4.5e-38 131.1 8.3 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TraQ PF09679.10 EOO03801.1 - 0.0031 17.4 0.4 0.013 15.4 0.1 2.2 2 0 0 2 2 2 1 Type-F conjugative transfer system pilin chaperone (TraQ) DUF4079 PF13301.6 EOO03801.1 - 0.0047 17.1 0.2 0.046 13.9 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4079) DUF1422 PF07226.11 EOO03801.1 - 0.058 13.4 0.9 2.1 8.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1422) MFS_1 PF07690.16 EOO03802.1 - 2.3e-18 66.3 17.2 3.1e-18 65.8 17.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CBM_2 PF00553.19 EOO03802.1 - 0.018 15.4 1.2 0.038 14.3 1.2 1.5 1 0 0 1 1 1 0 Cellulose binding domain adh_short PF00106.25 EOO03803.1 - 1e-29 103.4 0.0 1.4e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03803.1 - 8.6e-26 90.9 0.0 1.1e-25 90.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO03803.1 - 9.3e-05 22.4 0.0 0.00012 22.0 0.0 1.1 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 EOO03804.1 - 2.2e-31 109.1 21.1 2.1e-23 82.8 11.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO03804.1 - 6.4e-12 45.1 0.2 6.4e-12 45.1 0.2 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter PUCC PF03209.15 EOO03804.1 - 0.00028 20.0 6.2 0.028 13.4 4.1 2.7 2 1 1 3 3 3 2 PUCC protein NIR_SIR_ferr PF03460.17 EOO03804.1 - 0.18 11.7 0.3 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain OATP PF03137.20 EOO03804.1 - 1 7.6 13.3 0.026 12.8 2.5 3.0 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Aconitase PF00330.20 EOO03805.1 - 4.6e-31 108.3 0.2 1.7e-29 103.2 0.2 2.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EOO03805.1 - 1.2e-22 80.6 0.0 1.5e-12 48.0 0.1 2.3 2 0 0 2 2 2 2 Aconitase C-terminal domain MCM PF00493.23 EOO03805.1 - 0.15 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Egh16-like PF11327.8 EOO03806.1 - 5.1e-54 183.5 8.9 6.4e-54 183.1 8.9 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor I-set PF07679.16 EOO03806.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain Zn_clus PF00172.18 EOO03807.1 - 7.9e-07 29.1 9.1 1.5e-06 28.3 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRAPPC-Trs85 PF12739.7 EOO03808.1 - 2.5e-114 382.4 0.1 5.3e-114 381.3 0.1 1.5 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit BAR_2 PF10455.9 EOO03810.1 - 1.6e-59 201.4 0.2 2.2e-59 201.0 0.2 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EOO03810.1 - 1.6e-23 83.6 3.1 4.3e-22 78.9 3.1 2.1 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EOO03810.1 - 0.00049 19.9 0.8 0.0031 17.3 0.2 2.3 2 1 0 2 2 2 1 BAR domain of APPL family TauD PF02668.16 EOO03811.1 - 3.7e-43 148.3 0.0 5.1e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ax_dynein_light PF10211.9 EOO03811.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain NST1 PF13945.6 EOO03812.1 - 1.4e-52 178.6 11.2 1.4e-52 178.6 11.2 5.0 3 2 1 4 4 4 1 Salt tolerance down-regulator cobW PF02492.19 EOO03813.1 - 2.7e-39 134.6 0.2 3.9e-39 134.1 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EOO03813.1 - 1.8e-05 24.7 0.1 0.23 11.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EOO03813.1 - 0.00024 20.7 1.0 0.0012 18.5 1.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CobW_C PF07683.14 EOO03813.1 - 0.00069 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MMR_HSR1 PF01926.23 EOO03813.1 - 0.0026 17.8 0.0 0.0056 16.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 EOO03813.1 - 0.011 14.7 1.4 2.4 7.1 0.1 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EOO03813.1 - 0.017 15.5 0.0 0.051 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EOO03813.1 - 0.017 15.6 0.1 0.031 14.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EOO03813.1 - 0.029 14.6 0.2 0.43 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EOO03813.1 - 0.035 14.1 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EOO03813.1 - 0.046 14.3 0.1 0.2 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EOO03813.1 - 0.05 13.4 0.5 0.23 11.2 0.5 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Septin PF00735.18 EOO03813.1 - 0.057 12.7 0.5 9 5.5 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_29 PF13555.6 EOO03813.1 - 0.073 12.8 0.1 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EOO03813.1 - 0.16 11.7 0.9 0.48 10.1 0.9 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EOO03813.1 - 0.17 12.4 0.2 0.54 10.8 0.1 1.9 2 0 0 2 2 2 0 ABC transporter PLA2_B PF01735.18 EOO03814.1 - 1.1e-25 90.0 0.0 2.4e-25 88.9 0.0 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain PHO4 PF01384.20 EOO03816.1 - 3.9e-76 256.3 5.5 4.5e-76 256.1 5.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family Gram_pos_anchor PF00746.21 EOO03816.1 - 2.9 7.9 0.0 2.9 7.9 0.0 3.1 4 0 0 4 4 4 0 LPXTG cell wall anchor motif AMP-binding PF00501.28 EOO03817.1 - 2.9e-24 85.5 0.0 3.7e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EOO03817.1 - 4.4e-15 56.4 0.1 9.1e-15 55.4 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Amidohydro_1 PF01979.20 EOO03818.1 - 2.2e-21 76.5 4.2 8.4e-21 74.7 4.2 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EOO03818.1 - 2.8e-17 63.4 10.0 8.4e-15 55.2 7.3 2.4 1 1 1 2 2 2 2 Amidohydrolase family TrkA_N PF02254.18 EOO03818.1 - 0.011 16.0 1.1 0.037 14.3 0.3 2.3 2 1 0 2 2 2 0 TrkA-N domain SAP PF02037.27 EOO03818.1 - 0.12 12.1 0.2 0.21 11.4 0.2 1.4 1 0 0 1 1 1 0 SAP domain GST_N PF02798.20 EOO03819.1 - 2.4e-16 59.8 0.0 6.2e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EOO03819.1 - 8.4e-15 55.0 0.0 1.6e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EOO03819.1 - 7.9e-13 48.5 0.0 4.8e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EOO03819.1 - 3.1e-11 43.3 0.0 5.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EOO03819.1 - 1e-10 41.7 0.2 1.9e-10 40.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EOO03819.1 - 2.4e-08 33.9 1.2 4.7e-08 32.9 0.1 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain Aminotran_1_2 PF00155.21 EOO03820.1 - 1.7e-23 83.4 0.0 3.1e-23 82.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EOO03820.1 - 0.16 10.8 0.0 0.37 9.5 0.0 1.5 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase ETC_C1_NDUFA4 PF04800.12 EOO03821.1 - 2.6e-36 123.7 0.4 3.6e-36 123.3 0.4 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region VCBS PF13517.6 EOO03822.1 - 0.09 13.4 0.1 0.18 12.4 0.1 1.6 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella GH131_N PF18271.1 EOO03823.1 - 9.4e-83 277.8 0.1 1.1e-82 277.6 0.1 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Helo_like_N PF17111.5 EOO03824.1 - 3.5e-11 42.9 1.7 4.9e-11 42.4 1.7 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins GAS PF13851.6 EOO03824.1 - 0.0088 15.4 2.5 0.082 12.2 0.3 2.3 3 0 0 3 3 3 1 Growth-arrest specific micro-tubule binding Phage_HK97_TLTM PF06120.11 EOO03824.1 - 0.031 13.5 1.3 0.1 11.7 0.7 1.8 2 0 0 2 2 2 0 Tail length tape measure protein Lzipper-MIP1 PF14389.6 EOO03824.1 - 0.034 14.4 0.5 0.2 12.0 0.0 2.4 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 HMMR_C PF15908.5 EOO03824.1 - 0.059 13.6 0.1 0.2 11.9 0.1 1.8 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal COMP PF11598.8 EOO03824.1 - 0.094 13.2 1.0 20 5.7 0.1 3.4 4 0 0 4 4 4 0 Cartilage oligomeric matrix protein THOC7 PF05615.13 EOO03824.1 - 0.14 12.4 2.0 0.18 12.1 1.9 1.4 1 1 0 1 1 1 0 Tho complex subunit 7 DUF1664 PF07889.12 EOO03824.1 - 0.15 12.1 1.5 0.83 9.7 0.4 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) MCM PF00493.23 EOO03825.1 - 1.1e-103 345.2 0.3 1.6e-103 344.6 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EOO03825.1 - 1.1e-38 131.9 0.3 2.4e-38 130.8 0.3 1.6 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EOO03825.1 - 6.4e-30 103.6 0.1 1.7e-29 102.2 0.1 1.8 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 EOO03825.1 - 2.4e-24 85.9 0.1 1.7e-23 83.2 0.0 2.5 2 0 0 2 2 2 1 MCM N-terminal domain MCM_lid PF17855.1 EOO03825.1 - 4.2e-24 84.8 1.3 1.2e-23 83.3 0.2 2.4 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EOO03825.1 - 2.5e-07 30.3 0.0 7.5e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EOO03825.1 - 0.0014 18.4 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 EOO03825.1 - 0.0015 18.4 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GIDA_assoc PF13932.6 EOO03825.1 - 0.011 15.9 0.9 0.028 14.6 0.9 1.6 1 0 0 1 1 1 0 GidA associated domain CCDC53 PF10152.9 EOO03825.1 - 0.038 14.4 2.3 0.39 11.1 0.7 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex AAA_5 PF07728.14 EOO03825.1 - 0.047 13.7 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DJ-1_PfpI PF01965.24 EOO03826.1 - 4e-16 59.2 0.0 5.1e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Pribosyltran_N PF13793.6 EOO03827.1 - 5.7e-42 142.3 0.1 1.7e-40 137.6 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EOO03827.1 - 2e-36 125.8 0.1 2.4e-29 102.7 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EOO03827.1 - 2.7e-09 36.8 0.0 8.2e-06 25.4 0.1 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain ORC6 PF05460.13 EOO03827.1 - 0.048 12.9 4.0 0.067 12.5 4.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) UPRTase PF14681.6 EOO03827.1 - 0.051 13.0 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PGAP1 PF07819.13 EOO03828.1 - 0.0035 17.1 0.0 0.0095 15.7 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EOO03828.1 - 0.0073 16.9 0.1 0.01 16.5 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 EOO03828.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 EOO03828.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Picorna_P3A PF06363.11 EOO03828.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Picornaviridae P3A protein Hydrolase_4 PF12146.8 EOO03828.1 - 0.14 11.4 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DEAD PF00270.29 EOO03829.1 - 1.4e-49 168.2 0.0 8.9e-49 165.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EOO03829.1 - 9.9e-25 87.1 0.1 2.6e-23 82.5 0.1 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EOO03829.1 - 2.8e-22 78.7 2.8 2.8e-22 78.7 2.8 2.4 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Sorting_nexin PF03700.13 EOO03829.1 - 0.15 12.6 15.5 0.021 15.4 4.0 3.7 3 1 0 3 3 3 0 Sorting nexin, N-terminal domain TFIIF_alpha PF05793.12 EOO03830.1 - 0.0028 16.3 9.4 0.0028 16.3 9.4 2.4 1 1 1 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Asp PF00026.23 EOO03831.1 - 1.8e-69 234.6 11.5 2.2e-69 234.3 11.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EOO03831.1 - 0.00013 22.3 10.0 0.011 16.0 0.7 3.0 3 1 1 4 4 4 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EOO03831.1 - 0.00034 21.2 5.2 0.0039 17.8 1.5 3.1 2 1 0 2 2 2 1 Aspartyl protease RNase_H2_suC PF08615.11 EOO03832.1 - 3.2e-27 95.4 0.0 3.9e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF3659 PF12396.8 EOO03833.1 - 5.8e-16 58.2 8.5 1.8e-12 47.0 3.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) DUF913 PF06025.12 EOO03833.1 - 2.9 6.8 4.2 1.8 7.4 0.8 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 EOO03833.1 - 3.9 7.2 12.5 0.31 10.8 6.1 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Aa_trans PF01490.18 EOO03834.1 - 7.7e-58 196.1 32.4 8.7e-58 195.9 32.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF202 PF02656.15 EOO03834.1 - 0.037 14.5 2.5 0.037 14.5 2.5 5.2 4 3 0 4 4 4 0 Domain of unknown function (DUF202) Tetraspanin PF00335.20 EOO03834.1 - 0.051 13.3 0.1 0.051 13.3 0.1 3.2 3 1 1 4 4 4 0 Tetraspanin family RPE65 PF03055.15 EOO03835.1 - 4.1e-28 98.8 0.0 4.8e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Motile_Sperm PF00635.26 EOO03835.1 - 0.083 12.7 0.3 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 MSP (Major sperm protein) domain Metallophos PF00149.28 EOO03836.1 - 1.6e-31 110.4 0.1 7.3e-22 78.9 0.0 2.1 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EOO03836.1 - 0.0052 17.2 0.1 0.014 15.8 0.1 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain CREPT PF16566.5 EOO03837.1 - 0.0038 17.4 1.2 0.0046 17.1 1.2 1.2 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour HBS1_N PF08938.10 EOO03837.1 - 0.063 13.6 0.1 0.063 13.6 0.1 2.0 2 1 0 2 2 2 0 HBS1 N-terminus DUF4164 PF13747.6 EOO03837.1 - 0.097 13.0 5.0 0.19 12.0 4.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) FemAB PF02388.16 EOO03837.1 - 0.099 11.5 0.2 0.13 11.1 0.2 1.0 1 0 0 1 1 1 0 FemAB family 2OG-FeII_Oxy PF03171.20 EOO03838.1 - 2.5e-18 66.4 0.0 3.4e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SesA PF17107.5 EOO03839.1 - 0.0075 16.5 0.7 0.044 14.0 0.2 2.0 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases UPRTase PF14681.6 EOO03840.1 - 5.1e-41 140.4 0.0 7.6e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 EOO03840.1 - 9.7e-12 45.0 0.0 1.5e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 EOO03840.1 - 1.4e-05 25.0 0.0 4.4e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 EOO03840.1 - 3.9e-05 23.8 0.0 0.0002 21.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EOO03840.1 - 0.00021 21.9 0.0 0.00038 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EOO03840.1 - 0.0012 19.4 0.5 0.0027 18.2 0.4 1.6 1 1 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 EOO03840.1 - 0.0021 18.0 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 EOO03840.1 - 0.0044 16.8 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase AAA_17 PF13207.6 EOO03840.1 - 0.0097 16.3 0.0 0.57 10.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 EOO03840.1 - 0.0098 15.2 0.0 0.021 14.1 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin NB-ARC PF00931.22 EOO03840.1 - 0.01 15.0 0.2 0.03 13.5 0.2 1.6 1 1 0 1 1 1 0 NB-ARC domain DUF87 PF01935.17 EOO03840.1 - 0.015 15.4 0.7 0.034 14.2 0.7 1.7 1 1 0 1 1 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 EOO03840.1 - 0.016 15.1 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EOO03840.1 - 0.021 14.5 0.5 0.061 13.1 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EOO03840.1 - 0.07 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EOO03840.1 - 0.094 12.8 0.3 0.16 12.1 0.3 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 EOO03840.1 - 0.1 12.7 0.1 0.87 9.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EOO03840.1 - 0.12 12.6 0.1 0.29 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EOO03840.1 - 0.16 12.2 0.1 0.56 10.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain CoaE PF01121.20 EOO03840.1 - 0.62 9.7 2.7 0.86 9.3 0.1 2.4 3 0 0 3 3 3 0 Dephospho-CoA kinase AAA_23 PF13476.6 EOO03840.1 - 0.77 10.2 2.4 1.9 9.0 0.2 2.0 2 0 0 2 2 2 0 AAA domain CUE PF02845.16 EOO03841.1 - 3.3e-06 26.7 0.0 5.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain VIR_N PF15912.5 EOO03841.1 - 0.026 14.1 0.8 0.035 13.7 0.8 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal G2BR PF18442.1 EOO03841.1 - 0.026 14.2 6.8 0.062 13.0 6.8 1.7 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) Aldedh PF00171.22 EOO03841.1 - 0.24 9.9 2.1 0.32 9.5 2.1 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Ndc1_Nup PF09531.10 EOO03841.1 - 1.1 7.9 4.8 1.4 7.5 4.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GDA1_CD39 PF01150.17 EOO03842.1 - 2.7e-111 372.2 0.0 3.8e-111 371.8 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family F-box_4 PF15966.5 EOO03843.1 - 0.064 13.1 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 F-box Nucleoporin_FG PF13634.6 EOO03844.1 - 9.1e-12 45.7 39.6 9.1e-12 45.7 39.6 3.0 2 1 1 3 3 3 1 Nucleoporin FG repeat region DUF1664 PF07889.12 EOO03844.1 - 0.0015 18.6 0.2 1.6 8.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EOO03844.1 - 0.0061 16.6 0.4 0.8 9.7 0.0 2.4 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 EOO03844.1 - 0.13 12.4 0.2 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 EOO03844.1 - 0.26 9.2 0.1 0.78 7.6 0.0 1.6 2 0 0 2 2 2 0 Prominin Spt20 PF12090.8 EOO03844.1 - 3.6 7.1 9.4 6.2 6.4 9.4 1.5 1 0 0 1 1 1 0 Spt20 family Pyr_redox_2 PF07992.14 EOO03845.1 - 1.1e-42 146.3 0.0 1.6e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EOO03845.1 - 3.7e-14 53.0 0.0 3.8e-10 40.2 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 EOO03845.1 - 2.8e-07 29.6 0.3 7.1e-07 28.3 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EOO03845.1 - 1.3e-05 24.8 0.5 3.8e-05 23.3 0.5 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EOO03845.1 - 0.00011 22.5 0.1 0.00026 21.4 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EOO03845.1 - 0.00046 19.6 1.1 0.001 18.5 1.1 1.6 1 0 0 1 1 1 1 EF hand Kei1 PF08552.11 EOO03846.1 - 1.4e-49 168.5 14.6 7.1e-48 163.0 14.6 2.0 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 SPC12 PF06645.13 EOO03846.1 - 7.2 6.8 13.7 0.15 12.2 4.7 2.6 2 1 1 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) CLTH PF10607.9 EOO03847.1 - 8.5e-33 113.3 0.0 1.4e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EOO03847.1 - 6.4e-08 32.3 0.0 1.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 LisH adh_short PF00106.25 EOO03848.1 - 2.7e-32 111.8 0.0 1.2e-31 109.8 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03848.1 - 2.5e-18 66.5 0.0 7.1e-18 65.0 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO03848.1 - 6.4e-11 42.5 0.0 8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO03848.1 - 1.3e-05 24.8 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EOO03848.1 - 0.00092 19.5 0.1 0.0017 18.6 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EOO03848.1 - 0.0022 17.2 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EOO03848.1 - 0.0098 15.3 0.0 0.017 14.6 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EOO03848.1 - 0.098 11.6 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MOZ_SAS PF01853.18 EOO03849.1 - 6e-82 273.6 0.3 8.4e-82 273.2 0.3 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EOO03849.1 - 4.5e-23 80.6 1.8 8.4e-23 79.7 1.8 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EOO03849.1 - 4.8e-18 64.8 0.0 1.1e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EOO03849.1 - 0.00026 21.4 0.0 0.0005 20.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EOO03849.1 - 0.01 16.1 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DDRGK PF09756.9 EOO03849.1 - 0.026 14.1 0.2 0.026 14.1 0.2 2.1 2 1 0 2 2 2 0 DDRGK domain HTH_Crp_2 PF13545.6 EOO03849.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain CDC27 PF09507.10 EOO03850.1 - 4e-67 227.5 18.9 2.9e-39 135.7 15.4 2.0 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 DUF1428 PF07237.11 EOO03850.1 - 0.025 14.8 0.7 9.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1428) Ribosomal_S25 PF03297.15 EOO03850.1 - 0.056 13.6 2.1 0.091 13.0 0.0 2.2 2 0 0 2 2 2 0 S25 ribosomal protein Glyco_hydro_cc PF11790.8 EOO03852.1 - 4.7e-32 111.5 0.0 5.8e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RRM_1 PF00076.22 EOO03853.1 - 1.7e-25 88.6 0.6 1.2e-12 47.4 0.1 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EOO03853.1 - 0.00013 21.6 0.0 0.00078 19.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 EOO03853.1 - 0.21 11.4 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) PHM7_cyt PF14703.6 EOO03853.1 - 0.76 10.0 5.0 3.1 8.0 0.2 3.6 3 2 2 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter Whi5 PF08528.11 EOO03854.1 - 2.3e-06 27.1 1.6 2.6e-06 26.9 0.1 1.8 1 1 1 2 2 2 1 Whi5 like Tombus_P33 PF08500.10 EOO03854.1 - 0.11 12.4 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Tombusvirus p33 Utp11 PF03998.13 EOO03854.1 - 0.15 12.0 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Utp11 protein NAD_binding_10 PF13460.6 EOO03855.1 - 2.6e-10 40.5 0.0 6.9e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EOO03855.1 - 6.1e-08 32.4 0.0 8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EOO03855.1 - 7.3e-08 32.3 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EOO03855.1 - 1.6e-06 27.4 0.0 2.8e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EOO03855.1 - 0.00068 19.1 0.0 0.0046 16.4 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EOO03855.1 - 0.00086 18.5 0.0 0.0017 17.5 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EOO03855.1 - 0.0035 16.8 0.0 0.0063 16.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DUF4743 PF15916.5 EOO03857.1 - 3.8e-12 46.2 0.0 5.6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 EOO03857.1 - 4.3e-08 33.3 0.0 7.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain FSH1 PF03959.13 EOO03858.1 - 2.4e-21 76.4 0.0 3.8e-21 75.7 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) adh_short_C2 PF13561.6 EOO03860.1 - 7.7e-49 166.4 0.0 1.3e-48 165.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO03860.1 - 1.1e-44 152.2 0.1 1.6e-44 151.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO03860.1 - 1.3e-16 61.0 0.0 2.4e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 KR domain fn3 PF00041.21 EOO03860.1 - 9.6e-09 35.5 2.6 9.5e-06 25.9 0.0 2.9 3 0 0 3 3 3 2 Fibronectin type III domain Epimerase PF01370.21 EOO03860.1 - 0.039 13.4 0.0 0.1 12.0 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF924 PF06041.11 EOO03861.1 - 3.5e-17 63.1 0.0 5e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) MFS_1 PF07690.16 EOO03862.1 - 5.5e-10 38.7 43.0 3.2e-09 36.2 39.9 3.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EOO03862.1 - 2.4e-07 29.6 11.2 5e-07 28.5 11.1 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Bystin PF05291.11 EOO03863.1 - 2.7e-128 427.3 0.0 3.5e-128 427.0 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF4139 PF13598.6 EOO03864.1 - 1.3e-35 123.0 0.0 2.7e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 EOO03864.1 - 6.2e-31 106.7 0.4 6.2e-31 106.7 0.4 3.0 2 1 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.6 EOO03864.1 - 1.1 10.2 12.3 1.1 10.2 9.3 2.5 2 1 0 2 2 2 0 Nucleoporin FG repeat region LMBR1 PF04791.16 EOO03864.1 - 5.5 5.8 9.6 8.1 5.2 9.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Connexin PF00029.19 EOO03864.1 - 8.4 6.1 5.6 18 5.0 5.6 1.5 1 0 0 1 1 1 0 Connexin Fungal_trans PF04082.18 EOO03867.1 - 3.2e-42 144.4 0.0 4.7e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EOO03867.1 - 8.2e-09 35.4 6.5 2e-08 34.2 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 7tm_1 PF00001.21 EOO03868.1 - 4.4 6.5 10.4 0.092 12.0 3.0 1.8 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) FAD_binding_3 PF01494.19 EOO03869.1 - 2.5e-08 33.6 0.0 3.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 EOO03869.1 - 0.075 12.1 0.0 0.095 11.7 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase Peptidase_S8 PF00082.22 EOO03870.1 - 6.5e-52 176.6 3.3 1.2e-51 175.8 3.3 1.4 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EOO03870.1 - 0.0042 17.8 0.1 0.0088 16.7 0.1 1.5 1 0 0 1 1 1 1 Fn3-like domain Rick_17kDa_Anti PF05433.15 EOO03871.1 - 1e-06 28.5 5.6 1e-06 28.5 5.6 2.5 2 0 0 2 2 2 1 Glycine zipper 2TM domain TauE PF01925.19 EOO03871.1 - 0.025 14.2 2.9 0.036 13.7 2.9 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Gly-zipper_Omp PF13488.6 EOO03871.1 - 0.035 14.1 6.8 0.035 14.1 6.8 2.4 2 0 0 2 2 2 0 Glycine zipper DUF3659 PF12396.8 EOO03872.1 - 1.1e-98 323.1 56.6 1.2e-22 79.6 1.5 6.8 6 0 0 6 6 6 5 Protein of unknown function (DUF3659) LEA_4 PF02987.16 EOO03872.1 - 0.027 14.5 0.1 0.027 14.5 0.1 3.7 3 0 0 3 3 3 0 Late embryogenesis abundant protein GCV_T_C PF08669.11 EOO03872.1 - 0.042 13.8 3.4 3.1 7.8 0.0 4.1 4 0 0 4 4 4 0 Glycine cleavage T-protein C-terminal barrel domain CDC73_C PF05179.14 EOO03874.1 - 1.2e-56 190.7 0.0 2e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal BBE PF08031.12 EOO03875.1 - 0.018 15.1 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like Rad60-SLD_2 PF13881.6 EOO03876.1 - 1.8e-11 44.1 0.0 3.9e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EOO03876.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EOO03876.1 - 0.0026 18.3 0.9 0.0059 17.2 0.0 1.9 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain Ras PF00071.22 EOO03877.1 - 1.7e-59 200.0 0.3 2.3e-59 199.6 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EOO03877.1 - 2.6e-37 127.7 0.1 4.4e-37 127.0 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EOO03877.1 - 8e-18 64.5 0.3 9.9e-18 64.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EOO03877.1 - 4.6e-07 29.6 0.1 2.9e-06 27.0 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EOO03877.1 - 1.1e-05 24.9 0.0 1.7e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EOO03877.1 - 1.6e-05 24.9 0.0 3.8e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EOO03877.1 - 2.1e-05 24.0 0.3 2.7e-05 23.7 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EOO03877.1 - 0.00019 21.3 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 EOO03877.1 - 0.0046 16.8 0.1 0.013 15.3 0.0 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FlgH PF02107.16 EOO03877.1 - 0.031 13.9 0.7 0.043 13.4 0.7 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein TIR_2 PF13676.6 EOO03877.1 - 0.046 14.3 0.1 0.085 13.5 0.1 1.4 1 0 0 1 1 1 0 TIR domain AAA_28 PF13521.6 EOO03877.1 - 0.086 13.1 0.0 12 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain TetR_C_16 PF17920.1 EOO03877.1 - 0.17 12.1 0.0 0.59 10.4 0.0 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain tRNA-synt_1c PF00749.21 EOO03878.1 - 9.6e-102 340.1 0.0 1.4e-101 339.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EOO03878.1 - 2e-33 115.7 0.0 4e-32 111.5 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain MAS20 PF02064.15 EOO03878.1 - 0.99 9.5 4.1 2.4 8.3 4.1 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor Ribonucleas_3_3 PF14622.6 EOO03879.1 - 6.7e-05 23.0 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 EOO03879.1 - 0.0028 18.3 0.0 0.0048 17.6 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 EOO03879.1 - 0.049 14.3 0.0 0.21 12.2 0.0 2.0 1 1 0 1 1 1 0 Ribonuclease III domain CagZ PF09053.10 EOO03879.1 - 0.084 12.5 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 CagZ Oxidored_FMN PF00724.20 EOO03880.1 - 4.3e-87 292.6 0.0 4.9e-87 292.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HH_signal PF01085.18 EOO03880.1 - 0.07 12.8 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Hedgehog amino-terminal signalling domain Rib_5-P_isom_A PF06026.14 EOO03881.1 - 1.5e-48 164.6 0.0 2.3e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Methyltransf_23 PF13489.6 EOO03882.1 - 3.3e-18 66.1 0.0 4.7e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO03882.1 - 5.3e-11 43.1 0.0 1.2e-10 42.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO03882.1 - 3.9e-10 39.7 0.0 1.3e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EOO03882.1 - 2.4e-08 34.5 0.0 4.6e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO03882.1 - 6.2e-08 33.3 0.0 3.3e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EOO03882.1 - 0.00082 18.9 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EOO03882.1 - 0.0014 18.2 0.0 0.0044 16.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.20 EOO03882.1 - 0.0062 15.9 0.0 0.017 14.4 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EOO03882.1 - 0.0089 15.4 0.0 0.094 12.0 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EOO03882.1 - 0.0095 15.3 0.0 0.032 13.5 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_4 PF02390.17 EOO03882.1 - 0.0097 15.4 0.0 0.024 14.1 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.9 EOO03882.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_15 PF09445.10 EOO03882.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase LtrA PF06772.11 EOO03883.1 - 9e-14 51.4 17.1 2.3e-12 46.8 12.6 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Phage_holin_3_6 PF07332.11 EOO03883.1 - 0.02 14.9 0.2 0.02 14.9 0.2 2.9 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III TMEM100 PF16311.5 EOO03883.1 - 0.085 12.4 0.0 0.29 10.7 0.0 1.9 1 0 0 1 1 1 0 Transmembrane protein 100 DUF2157 PF09925.9 EOO03883.1 - 0.47 10.2 15.5 0.25 11.1 1.9 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) NOT2_3_5 PF04153.18 EOO03884.1 - 1.2e-29 103.0 0.5 1.7e-29 102.5 0.5 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Pro-kuma_activ PF09286.11 EOO03885.1 - 1.2e-30 106.6 0.2 2.9e-30 105.4 0.1 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EOO03885.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Subtilase family zf-C3HC4_3 PF13920.6 EOO03886.1 - 2.9e-09 36.6 12.6 5e-09 35.9 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AWPM-19 PF05512.11 EOO03886.1 - 0.046 13.9 0.2 0.15 12.3 0.2 1.8 1 0 0 1 1 1 0 AWPM-19-like family Prok-RING_4 PF14447.6 EOO03886.1 - 0.059 13.2 12.9 0.1 12.5 12.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Pentapeptide_2 PF01469.18 EOO03887.1 - 0.0049 16.7 5.5 0.0049 16.7 5.5 3.7 3 1 0 3 3 3 1 Pentapeptide repeats (8 copies) DUF775 PF05603.12 EOO03888.1 - 1.3e-61 207.6 0.0 1.8e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Cas_GSU0053 PF09617.10 EOO03888.1 - 0.04 13.9 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) zf-C2HC5 PF06221.13 EOO03889.1 - 1.7e-22 79.2 6.9 3e-22 78.4 6.9 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Na_Ca_ex PF01699.24 EOO03890.1 - 5.1e-46 156.4 33.8 1.1e-23 83.8 12.1 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CPP1-like PF11833.8 EOO03890.1 - 2.2 7.9 14.8 0.21 11.2 7.7 2.6 2 1 1 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF3433 PF11915.8 EOO03891.1 - 1.1e-11 45.1 4.7 1.1e-11 45.1 4.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) Cation_efflux PF01545.21 EOO03892.1 - 5.7e-38 130.6 1.7 9.2e-38 130.0 1.7 1.3 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 EOO03892.1 - 0.015 14.4 0.8 0.015 14.4 0.8 2.6 3 0 0 3 3 3 0 Branched-chain amino acid transport system / permease component ORF_2_N PF18492.1 EOO03892.1 - 0.13 12.5 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Open reading frame 2 N-terminal domain Ribosomal_60s PF00428.19 EOO03892.1 - 0.5 11.0 9.2 0.93 10.1 9.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein YdjM PF04307.14 EOO03892.1 - 0.79 9.0 4.9 0.15 11.4 0.2 2.2 2 1 0 2 2 2 0 LexA-binding, inner membrane-associated putative hydrolase Macro PF01661.21 EOO03893.1 - 4.5e-39 133.1 0.2 6.6e-39 132.6 0.2 1.2 1 0 0 1 1 1 1 Macro domain RGS PF00615.19 EOO03894.1 - 1.2e-37 128.8 0.1 5.1e-37 126.8 0.0 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 EOO03894.1 - 1.9e-25 88.7 0.0 5.6e-21 74.4 0.0 3.4 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Replic_Relax PF13814.6 EOO03894.1 - 0.013 15.5 0.0 0.99 9.4 0.0 2.3 2 0 0 2 2 2 0 Replication-relaxation NMT PF01233.19 EOO03894.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain DEAD PF00270.29 EOO03895.1 - 1.9e-42 145.0 0.0 4.1e-42 143.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EOO03895.1 - 3.4e-22 78.9 0.0 4.2e-20 72.2 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO03895.1 - 0.0035 17.3 0.0 0.0063 16.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EOO03895.1 - 0.0047 16.2 0.0 0.0079 15.4 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Ketoacyl-synt_C PF02801.22 EOO03896.1 - 4.6e-37 126.6 0.1 7.4e-37 126.0 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EOO03896.1 - 1e-20 74.2 0.1 2.1e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ketoacyl-synt PF00109.26 EOO03896.1 - 0.00047 19.8 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Hamartin PF04388.12 EOO03897.1 - 0.061 12.0 0.1 0.061 12.0 0.1 2.1 2 0 0 2 2 2 0 Hamartin protein RNA_pol_3_Rpc31 PF11705.8 EOO03898.1 - 4e-48 164.6 3.4 4e-48 164.6 3.4 1.8 1 1 1 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 adh_short PF00106.25 EOO03899.1 - 1.5e-50 171.4 0.0 1.9e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO03899.1 - 6e-34 117.6 0.0 7.5e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO03899.1 - 7.3e-13 48.8 0.0 1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EOO03899.1 - 0.022 13.9 0.1 0.047 12.8 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EOO03899.1 - 0.041 14.2 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Syja_N PF02383.18 EOO03900.1 - 2.3e-78 263.7 0.1 5.6e-78 262.5 0.0 1.7 2 0 0 2 2 2 1 SacI homology domain RasGAP_C PF03836.15 EOO03900.1 - 0.012 15.8 0.4 1.4 9.1 0.1 2.6 2 0 0 2 2 2 0 RasGAP C-terminus WYL PF13280.6 EOO03900.1 - 0.015 15.3 0.2 0.078 13.0 0.0 2.2 3 0 0 3 3 3 0 WYL domain TPP_enzyme_N PF02776.18 EOO03901.1 - 3.3e-56 189.6 0.1 2e-54 183.8 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EOO03901.1 - 3.5e-50 169.8 0.1 6e-49 165.8 0.1 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EOO03901.1 - 6.6e-40 136.0 1.4 1e-39 135.4 0.3 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain MFS_1 PF07690.16 EOO03902.1 - 4.5e-29 101.5 53.3 1.1e-27 96.9 42.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1938 PF09153.10 EOO03902.1 - 0.069 13.2 0.0 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1938) Spo7 PF03907.13 EOO03903.1 - 1.1e-95 319.3 0.2 1.8e-95 318.6 0.0 1.4 2 0 0 2 2 2 1 Spo7-like protein DUF565 PF04483.12 EOO03903.1 - 0.38 11.3 1.1 1.1 9.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF565) UQ_con PF00179.26 EOO03904.1 - 4.6e-40 136.5 0.0 5.6e-40 136.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EOO03904.1 - 0.00087 19.0 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EOO03904.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 EOO03904.1 - 0.14 12.4 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain Glyco_hydro_7 PF00840.20 EOO03905.1 - 2.6e-98 329.6 4.1 2.9e-98 329.4 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CsbD PF05532.12 EOO03906.1 - 7.2e-06 25.8 7.6 0.00035 20.4 1.0 2.3 2 0 0 2 2 2 2 CsbD-like CN_hydrolase PF00795.22 EOO03907.1 - 3.2e-30 105.4 0.0 4.2e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Septin PF00735.18 EOO03908.1 - 3.8e-119 397.1 0.4 3.8e-119 397.1 0.4 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EOO03908.1 - 1.2e-08 35.0 1.0 2.7e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EOO03908.1 - 4e-06 26.5 2.2 0.00027 20.6 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EOO03908.1 - 3.4e-05 23.8 3.1 0.0025 17.8 0.9 3.3 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EOO03908.1 - 0.00033 21.2 4.4 0.021 15.3 0.0 2.9 2 1 0 3 3 3 1 ABC transporter Roc PF08477.13 EOO03908.1 - 0.0012 19.1 0.0 0.0031 17.7 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EOO03908.1 - 0.0014 18.0 2.2 0.0023 17.3 0.0 2.2 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.6 EOO03908.1 - 0.0018 18.7 0.2 0.005 17.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.22 EOO03908.1 - 0.0085 15.7 0.1 0.035 13.7 0.0 2.1 2 0 0 2 2 2 1 Ras family AAA_22 PF13401.6 EOO03908.1 - 0.0094 16.2 1.5 0.029 14.6 0.1 2.5 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EOO03908.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EOO03908.1 - 0.044 14.2 1.0 0.56 10.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 EOO03908.1 - 0.05 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 EOO03908.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EOO03908.1 - 0.087 12.9 8.4 0.82 9.7 0.0 3.6 3 1 0 3 3 3 0 Dynamin family AAA_7 PF12775.7 EOO03908.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 EOO03908.1 - 0.19 11.5 3.0 7.8 6.2 0.0 3.2 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein FAP PF07174.11 EOO03908.1 - 0.53 9.7 5.1 0.75 9.2 5.1 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Exonuc_VII_L PF02601.15 EOO03908.1 - 0.91 9.0 8.2 1.5 8.3 8.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3987 PF13148.6 EOO03908.1 - 1.8 7.5 0.0 1.8 7.5 0.0 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF3987) DUF87 PF01935.17 EOO03908.1 - 8.5 6.4 7.3 4.3 7.4 0.0 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain Sugar_tr PF00083.24 EOO03909.1 - 4.1e-45 154.5 17.4 5.2e-45 154.1 17.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO03909.1 - 1e-16 60.8 25.6 1.6e-16 60.2 25.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily tRNA-Thr_ED PF08915.11 EOO03909.1 - 0.23 11.5 0.0 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase Nuc_deoxyri_tr2 PF15891.5 EOO03910.1 - 1.5e-36 125.0 0.0 2e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like muHD PF10291.9 EOO03910.1 - 0.045 13.2 0.0 0.29 10.5 0.0 1.9 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain NAD_binding_10 PF13460.6 EOO03911.1 - 2.8e-12 46.9 0.0 4.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EOO03911.1 - 3e-12 46.6 0.0 4.8e-12 45.9 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EOO03911.1 - 6.9e-07 29.6 0.0 1.3e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EOO03911.1 - 9.5e-07 28.5 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EOO03911.1 - 0.0096 16.4 0.2 0.02 15.3 0.2 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 EOO03911.1 - 0.019 15.2 0.1 0.038 14.2 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.22 EOO03911.1 - 0.024 15.5 0.1 0.044 14.6 0.1 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold UPF0146 PF03686.13 EOO03911.1 - 0.026 14.4 0.0 0.079 12.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) GDP_Man_Dehyd PF16363.5 EOO03911.1 - 0.031 13.7 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 EOO03911.1 - 0.034 14.7 1.5 0.073 13.7 1.5 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 EOO03911.1 - 0.043 12.8 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.19 EOO03911.1 - 0.062 12.7 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EOO03911.1 - 0.11 13.0 0.2 0.23 12.0 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 EOO03911.1 - 0.12 12.6 0.1 0.26 11.4 0.0 1.6 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 EOO03911.1 - 0.12 11.8 1.5 0.23 10.9 1.0 1.7 1 1 1 2 2 2 0 short chain dehydrogenase DFP PF04127.15 EOO03911.1 - 0.15 11.9 0.3 0.26 11.1 0.3 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein MFS_1 PF07690.16 EOO03912.1 - 9.3e-37 126.8 31.0 1.7e-32 112.8 17.4 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO03912.1 - 6.7e-15 54.9 27.6 3.4e-14 52.6 12.1 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EOO03912.1 - 2.7e-07 29.4 7.3 2.7e-07 29.4 7.3 2.2 1 1 2 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DJ-1_PfpI PF01965.24 EOO03912.1 - 0.014 15.2 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family BT1 PF03092.16 EOO03912.1 - 0.65 8.2 10.1 0.023 13.0 1.9 2.5 2 1 0 3 3 3 0 BT1 family PrgI PF12666.7 EOO03912.1 - 3.3 8.5 0.0 3.3 8.5 0.0 3.8 3 1 1 4 4 4 0 PrgI family protein RabGAP-TBC PF00566.18 EOO03913.1 - 3.1e-32 112.0 0.0 1.1e-30 106.9 0.0 2.6 2 1 0 2 2 2 2 Rab-GTPase-TBC domain OPT PF03169.15 EOO03914.1 - 9.3e-66 222.7 15.3 1.1e-65 222.5 15.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_3_7 PF05449.11 EOO03914.1 - 2.5 8.2 6.8 0.32 11.0 0.5 2.6 3 0 0 3 3 3 0 Putative 3TM holin, Phage_holin_3 DUF2207 PF09972.9 EOO03914.1 - 5.8 5.5 7.7 2.7 6.6 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MFS_1 PF07690.16 EOO03915.1 - 3.6e-32 111.6 27.7 5.6e-32 111.0 27.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1648 PF07853.11 EOO03915.1 - 0.26 11.0 4.3 7.5 6.3 0.3 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1648) MFS_1 PF07690.16 EOO03920.1 - 7.9e-39 133.6 22.7 6e-38 130.7 23.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily YfhO PF09586.10 EOO03920.1 - 0.29 9.3 2.7 0.61 8.2 2.7 1.5 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF3671 PF12420.8 EOO03920.1 - 5.2 7.2 6.5 13 5.9 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function Sec7 PF01369.20 EOO03921.1 - 5.3e-70 234.8 0.4 5.3e-70 234.8 0.4 2.6 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 EOO03921.1 - 4.6e-41 140.4 1.1 4.6e-41 140.4 1.1 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EOO03921.1 - 2.6e-34 116.9 8.8 4e-33 113.1 0.1 5.2 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 EOO03921.1 - 3.3e-22 79.0 3.0 2e-20 73.2 0.2 3.3 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1749 PF08538.10 EOO03921.1 - 0.21 10.6 0.4 0.38 9.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Sugar_tr PF00083.24 EOO03922.1 - 8.4e-122 407.3 17.5 1.4e-121 406.5 17.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO03922.1 - 4.9e-22 78.3 53.9 3.1e-11 42.8 27.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5395 PF17373.2 EOO03924.1 - 0.05 14.2 1.2 0.13 13.0 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5395) WDCP PF15390.6 EOO03924.1 - 1 7.7 6.0 1.6 7.0 6.0 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family gpW PF02831.15 EOO03924.1 - 1.9 8.4 7.1 1.8 8.6 0.0 3.9 4 0 0 4 4 4 0 gpW WLM PF08325.10 EOO03925.1 - 0.00094 19.3 0.1 0.0028 17.8 0.1 1.7 1 0 0 1 1 1 1 WLM domain RSN1_7TM PF02714.15 EOO03927.1 - 1.5e-83 280.3 23.2 1.5e-83 280.3 23.2 1.5 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EOO03927.1 - 5.3e-32 111.4 4.0 3.8e-17 63.1 0.0 2.6 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EOO03927.1 - 6.8e-16 58.2 0.0 2.1e-15 56.6 0.0 1.9 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RSN1_TM PF13967.6 EOO03927.1 - 9.4e-11 41.7 0.1 9.4e-11 41.7 0.1 3.2 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport TAF4 PF05236.14 EOO03927.1 - 0.00064 19.6 2.2 0.0013 18.6 2.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF5409 PF17421.2 EOO03927.1 - 0.2 12.4 1.4 2 9.2 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5409) PIEZO PF15917.5 EOO03927.1 - 0.97 8.9 9.6 2.4 7.6 9.6 1.6 1 0 0 1 1 1 0 Piezo DUF4746 PF15928.5 EOO03927.1 - 1.3 8.4 7.1 3.1 7.1 6.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF1077 PF06417.12 EOO03928.1 - 5.8e-43 145.7 5.0 7.6e-43 145.3 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF3796 PF12676.7 EOO03928.1 - 0.013 15.9 0.1 0.017 15.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) Snf7 PF03357.21 EOO03929.1 - 2.9e-19 69.3 13.9 2.9e-19 69.3 13.9 2.0 1 1 1 2 2 2 1 Snf7 Phage_int_SAM_1 PF02899.17 EOO03929.1 - 0.096 13.0 2.7 0.22 11.8 1.2 2.5 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Radical_SAM PF04055.21 EOO03929.1 - 0.1 12.9 0.5 0.59 10.5 0.2 2.1 1 1 1 2 2 2 0 Radical SAM superfamily Spore_III_AB PF09548.10 EOO03929.1 - 0.49 10.5 9.7 0.5 10.5 4.5 2.9 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Ccdc124 PF06244.12 EOO03930.1 - 7.1e-28 97.7 23.0 7.1e-28 97.7 23.0 2.5 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 RNase_PH PF01138.21 EOO03931.1 - 7.1e-11 42.7 0.3 3.4e-10 40.5 0.1 2.1 3 0 0 3 3 3 1 3' exoribonuclease family, domain 1 S4 PF01479.25 EOO03932.1 - 3.6e-15 55.4 0.0 8e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EOO03932.1 - 0.0047 16.7 0.2 0.04 13.7 0.0 2.2 2 0 0 2 2 2 1 S4 domain EcKinase PF02958.20 EOO03933.1 - 1.2e-18 67.4 0.0 3e-17 62.9 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 EOO03933.1 - 2.5e-10 40.7 0.0 4.1e-10 40.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EOO03933.1 - 5.3e-08 32.1 0.0 2.3e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Kelch_5 PF13854.6 EOO03934.1 - 3.3e-14 52.5 12.9 4.4e-12 45.7 0.2 5.1 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 EOO03934.1 - 0.00077 19.0 6.7 0.067 12.8 0.0 4.1 3 1 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 EOO03934.1 - 0.0029 17.8 3.0 7.3 7.0 0.1 4.8 4 1 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 EOO03934.1 - 0.031 14.3 4.0 3.5 7.7 0.0 5.1 7 0 0 7 7 7 0 Galactose oxidase, central domain TauD PF02668.16 EOO03935.1 - 6.1e-50 170.5 0.2 6.9e-50 170.3 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family End3 PF12761.7 EOO03936.1 - 2e-78 263.2 6.2 2.6e-78 262.8 6.2 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 EOO03936.1 - 6e-48 161.1 0.0 3e-47 158.9 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EOO03936.1 - 3.8e-07 29.2 0.2 8.3e-07 28.1 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EOO03936.1 - 1.4e-05 25.4 0.0 4.5e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EOO03936.1 - 0.00088 19.0 0.2 0.0028 17.5 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 EOO03936.1 - 0.0019 18.0 0.1 0.004 17.0 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair DUF2408 PF10303.9 EOO03936.1 - 0.0024 18.4 1.6 0.0048 17.5 1.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2408) EF-hand_5 PF13202.6 EOO03936.1 - 0.016 14.7 0.1 0.061 12.9 0.1 2.0 1 0 0 1 1 1 0 EF hand NPV_P10 PF05531.12 EOO03936.1 - 0.13 12.8 1.6 31 5.1 0.1 3.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 EOO03936.1 - 0.29 11.2 2.4 2.1 8.4 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CSN5_C PF18323.1 EOO03936.1 - 0.32 11.9 5.3 0.23 12.4 2.3 2.3 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain KxDL PF10241.9 EOO03936.1 - 0.42 10.9 2.7 8.7 6.7 0.3 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein FlaC_arch PF05377.11 EOO03936.1 - 1 9.8 5.0 9.8 6.7 0.1 2.9 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Dad3 PF08656.10 EOO03936.1 - 1.9 8.7 5.1 17 5.5 0.5 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad3 EMP24_GP25L PF01105.24 EOO03936.1 - 2.8 7.8 4.9 8.9 6.2 0.1 2.6 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD UPF0242 PF06785.11 EOO03936.1 - 4.9 7.2 11.0 11 6.1 11.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus XAP5 PF04921.14 EOO03937.1 - 7.6e-96 320.7 0.7 9.4e-96 320.4 0.0 1.5 2 0 0 2 2 2 1 XAP5, circadian clock regulator Methyltransf_10 PF05971.12 EOO03937.1 - 7.7e-66 222.4 0.0 1.1e-65 221.9 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 EOO03937.1 - 0.002 17.7 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF4604 PF15377.6 EOO03937.1 - 0.0028 18.1 5.9 0.0028 18.1 5.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4604) Sugar_tr PF00083.24 EOO03938.1 - 8e-75 252.4 24.4 9.7e-75 252.1 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO03938.1 - 3.1e-22 79.0 29.5 1.4e-20 73.5 16.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FNIP_N PF14636.6 EOO03939.1 - 5.7e-27 95.6 0.5 2.7e-21 77.2 0.1 4.9 3 2 1 5 5 5 2 Folliculin-interacting protein N-terminus FNIP_C PF14638.6 EOO03939.1 - 0.044 13.4 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus Sigma_reg_N PF13800.6 EOO03940.1 - 1.5 9.2 5.7 16 5.8 4.8 2.4 1 1 1 2 2 2 0 Sigma factor regulator N-terminal TMCO5 PF14992.6 EOO03940.1 - 3.3 7.2 5.4 3.9 7.0 5.4 1.1 1 0 0 1 1 1 0 TMCO5 family Arm PF00514.23 EOO03941.1 - 0.013 15.5 0.9 15 5.8 0.3 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EOO03941.1 - 0.024 15.2 1.2 6.9 7.3 0.0 3.9 4 0 0 4 4 4 0 HEAT-like repeat HEAT PF02985.22 EOO03941.1 - 0.047 14.0 0.5 1.2 9.6 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat RTP1_C1 PF10363.9 EOO03941.1 - 0.087 13.0 1.5 1 9.6 0.3 3.2 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HsbA PF12296.8 EOO03941.1 - 0.2 12.1 2.5 1.4 9.4 0.2 3.2 3 0 0 3 3 3 0 Hydrophobic surface binding protein A DNA_pol_phi PF04931.13 EOO03941.1 - 0.46 8.5 11.3 0.39 8.8 9.1 2.0 2 0 0 2 2 2 0 DNA polymerase phi DUF1996 PF09362.10 EOO03943.1 - 7.4e-72 242.1 2.0 1e-71 241.6 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DAO PF01266.24 EOO03944.1 - 3.3e-09 36.8 0.0 3.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EOO03944.1 - 0.032 13.3 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 EOO03944.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Amidohydro_1 PF01979.20 EOO03945.1 - 2.6e-56 191.4 0.0 3.9e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EOO03945.1 - 6.8e-11 42.3 0.0 2.1e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family SIR2 PF02146.17 EOO03946.1 - 2.4e-09 37.3 0.0 4.2e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family MatE PF01554.18 EOO03947.1 - 7.9e-57 191.4 30.1 1.8e-32 112.2 10.5 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EOO03947.1 - 0.00014 22.0 17.6 0.0022 18.1 10.2 3.9 3 2 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF4311 PF14188.6 EOO03947.1 - 0.67 9.7 7.8 0.063 13.1 2.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4311) Peptidase_S41 PF03572.18 EOO03948.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S41 4HPAD_g_N PF18671.1 EOO03949.1 - 0.072 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal ExoD PF06055.12 EOO03949.1 - 0.12 11.7 2.2 0.19 11.1 0.4 1.9 1 1 1 2 2 2 0 Exopolysaccharide synthesis, ExoD ADH_zinc_N_2 PF13602.6 EOO03949.1 - 0.17 12.9 0.1 0.89 10.6 0.0 1.9 1 1 1 2 2 2 0 Zinc-binding dehydrogenase ORC4_C PF14629.6 EOO03950.1 - 2.2e-69 233.2 0.0 3.3e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus PHD_2 PF13831.6 EOO03950.1 - 5e-14 51.6 1.6 5e-14 51.6 1.6 1.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EOO03950.1 - 2.2e-11 43.4 5.1 3.9e-11 42.7 5.1 1.4 1 0 0 1 1 1 1 PHD-finger AAA_16 PF13191.6 EOO03950.1 - 2.7e-09 37.6 0.4 7.8e-07 29.6 0.4 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EOO03950.1 - 7.1e-05 23.2 0.9 0.00048 20.5 0.9 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EOO03950.1 - 0.00014 22.2 1.6 0.0016 18.7 1.6 2.5 1 1 0 1 1 1 1 AAA domain C1_1 PF00130.22 EOO03950.1 - 0.005 16.7 0.2 0.01 15.7 0.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 EOO03950.1 - 0.0055 16.9 0.7 0.014 15.6 0.7 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger NACHT PF05729.12 EOO03950.1 - 0.01 15.8 0.2 0.42 10.5 0.1 2.3 2 0 0 2 2 2 0 NACHT domain C1_2 PF03107.16 EOO03950.1 - 0.035 14.4 2.1 0.078 13.3 2.1 1.6 1 0 0 1 1 1 0 C1 domain AAA_14 PF13173.6 EOO03950.1 - 0.049 13.7 0.1 0.17 11.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain Prok-RING_1 PF14446.6 EOO03950.1 - 0.086 12.8 3.7 0.16 11.9 3.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 AAA_19 PF13245.6 EOO03950.1 - 0.15 12.4 0.1 0.35 11.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain Zn_clus PF00172.18 EOO03951.1 - 3.9e-06 26.9 11.7 6e-06 26.3 11.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Catalase PF00199.19 EOO03952.1 - 4e-20 72.3 0.0 2.3e-18 66.5 0.0 2.1 1 1 0 1 1 1 1 Catalase ABC_tran PF00005.27 EOO03953.1 - 3.4e-22 79.4 0.0 4.6e-09 36.9 0.0 3.7 2 2 0 2 2 2 2 ABC transporter SbcCD_C PF13558.6 EOO03953.1 - 4.7e-08 33.2 0.1 0.00024 21.3 0.1 2.7 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EOO03953.1 - 2.6e-07 30.8 2.0 0.029 14.2 0.4 3.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EOO03953.1 - 9.1e-05 23.0 0.0 0.061 13.8 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EOO03953.1 - 0.0018 18.0 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 EOO03953.1 - 0.02 14.6 0.0 4.1 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EOO03953.1 - 0.03 13.8 0.0 3.3 7.1 0.0 3.1 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EOO03953.1 - 0.036 14.4 0.1 3 8.2 0.0 2.6 2 2 0 2 2 2 0 AAA ATPase domain Ploopntkinase1 PF18748.1 EOO03953.1 - 0.055 13.0 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 AAA_22 PF13401.6 EOO03953.1 - 0.062 13.6 0.0 3.2 8.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EOO03953.1 - 0.083 13.4 0.0 3.3 8.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EOO03953.1 - 0.091 12.9 0.0 2.3 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EOO03953.1 - 0.13 12.7 0.1 1.1 9.7 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EOO03953.1 - 0.16 12.4 0.0 2.9 8.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.6 EOO03953.1 - 0.19 11.4 0.0 14 5.3 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 EOO03954.1 - 4.8e-16 59.4 0.1 2.6e-15 57.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EOO03954.1 - 0.0027 17.7 0.0 0.0075 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EOO03954.1 - 0.011 16.0 4.3 0.053 13.8 0.2 3.0 2 1 1 3 3 3 0 AAA domain AAA_30 PF13604.6 EOO03954.1 - 0.014 15.1 0.0 0.094 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EOO03954.1 - 0.029 14.8 1.0 0.15 12.4 1.0 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EOO03954.1 - 0.055 14.0 0.0 0.31 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EOO03954.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EOO03954.1 - 0.15 11.8 0.0 0.15 11.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain HEAT_2 PF13646.6 EOO03955.1 - 0.21 12.0 6.4 1.7 9.1 0.1 2.7 3 0 0 3 3 3 0 HEAT repeats Cupin_6 PF12852.7 EOO03955.1 - 0.31 10.8 4.2 0.18 11.5 0.6 2.4 3 0 0 3 3 3 0 Cupin Transp_cyt_pur PF02133.15 EOO03956.1 - 6.4e-25 87.8 30.5 4.5e-24 85.0 30.5 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sec7 PF01369.20 EOO03957.1 - 6.6e-65 218.2 0.0 1.2e-64 217.4 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EOO03957.1 - 8.6e-17 61.5 0.0 3.3e-16 59.6 0.0 2.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EOO03957.1 - 0.0031 17.2 1.3 0.0055 16.4 0.0 2.0 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 p450 PF00067.22 EOO03958.1 - 2e-52 178.5 0.0 2.7e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.14 EOO03959.1 - 5.1e-39 134.3 4.0 6.4e-39 133.9 4.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EOO03959.1 - 5.2e-10 39.7 4.5 4.9e-06 27.0 2.7 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EOO03959.1 - 1.4e-06 27.7 0.1 0.00043 19.5 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EOO03959.1 - 0.0015 17.7 1.0 0.035 13.2 0.0 2.7 2 1 1 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EOO03959.1 - 0.011 15.7 1.1 1.2 9.1 0.0 3.3 3 1 1 4 4 4 0 FAD-NAD(P)-binding TrkA_N PF02254.18 EOO03959.1 - 0.011 16.0 1.0 1.7 8.9 0.0 3.0 2 1 1 3 3 3 0 TrkA-N domain DAO PF01266.24 EOO03959.1 - 0.012 15.2 8.1 0.34 10.4 0.0 3.5 2 2 1 4 4 4 0 FAD dependent oxidoreductase Thi4 PF01946.17 EOO03959.1 - 0.014 14.6 1.6 0.58 9.4 0.0 2.5 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.6 EOO03959.1 - 0.017 15.3 0.2 0.094 13.0 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EOO03959.1 - 0.021 13.6 2.2 3.2 6.4 0.0 3.5 3 1 1 4 4 4 0 HI0933-like protein F1F0-ATPsyn_F PF10791.9 EOO03960.1 - 3.8e-41 139.4 0.5 4.4e-41 139.3 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi RNase_T PF00929.24 EOO03961.1 - 3.2e-18 66.8 0.0 4.9e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EOO03961.1 - 0.027 14.2 0.0 0.086 12.5 0.0 1.9 1 1 0 1 1 1 0 3'-5' exonuclease Ank_2 PF12796.7 EOO03962.1 - 3.1e-57 191.1 8.1 4.6e-16 59.2 0.1 5.2 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EOO03962.1 - 1.6e-51 172.0 6.9 1.6e-13 50.8 0.1 7.6 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 EOO03962.1 - 1.2e-46 155.2 17.4 6.6e-07 29.5 0.1 9.4 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 EOO03962.1 - 2.3e-40 132.0 5.3 5.8e-05 23.2 0.0 9.5 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 EOO03962.1 - 2.4e-31 107.4 15.7 7.2e-08 32.5 0.4 7.1 2 2 5 7 7 7 7 Ankyrin repeats (many copies) EccE PF11203.8 EOO03962.1 - 0.075 13.4 4.1 0.19 12.1 1.9 2.6 2 1 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE NTP_transf_9 PF04248.12 EOO03963.1 - 8.6e-33 112.1 1.5 9.7e-33 111.9 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) GFA PF04828.14 EOO03964.1 - 8.9e-11 42.0 0.1 8.9e-11 42.0 0.1 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme HypD PF01924.16 EOO03964.1 - 0.021 13.9 0.2 0.027 13.6 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family LSM PF01423.22 EOO03965.1 - 1.8e-16 59.6 0.0 2.5e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EOO03965.1 - 0.011 15.9 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF3552 PF12072.8 EOO03966.1 - 0.066 12.6 1.1 0.094 12.1 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) SMC_N PF02463.19 EOO03967.1 - 1.1e-68 231.0 8.7 2.3e-67 226.6 8.7 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EOO03967.1 - 1.4e-22 80.2 1.6 1e-21 77.4 0.2 3.0 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EOO03967.1 - 1.1e-08 35.8 19.0 1.1e-08 35.8 19.0 6.9 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.6 EOO03967.1 - 1.6e-08 34.7 10.3 0.00076 19.4 0.0 4.6 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EOO03967.1 - 0.0011 18.7 0.1 0.0025 17.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain HIP1_clath_bdg PF16515.5 EOO03967.1 - 0.0061 17.1 8.2 0.0061 17.1 8.2 8.7 3 2 5 8 8 8 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Phage_1_1 PF08200.11 EOO03967.1 - 0.051 14.0 0.2 0.58 10.6 0.2 3.1 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein ADH_N PF08240.12 EOO03968.1 - 1.4e-08 34.6 1.7 8.9e-08 32.0 0.1 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EOO03968.1 - 0.0002 22.4 0.0 0.00031 21.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EOO03968.1 - 0.0059 16.6 0.0 0.009 16.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ldh_1_C PF02866.18 EOO03969.1 - 3.7e-46 157.1 0.0 8.3e-46 156.0 0.0 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EOO03969.1 - 1.5e-42 145.0 0.0 2.9e-42 144.1 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EOO03969.1 - 0.00084 18.4 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family LPD38 PF18857.1 EOO03970.1 - 0.0057 16.8 0.1 0.009 16.2 0.1 1.3 1 0 0 1 1 1 1 Large polyvalent protein associated domain 38 DUF642 PF04862.12 EOO03970.1 - 0.01 15.6 0.6 0.059 13.2 0.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF642) 2OG-FeII_Oxy_2 PF13532.6 EOO03971.1 - 1.5e-37 129.7 0.0 2e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 EOO03971.1 - 9.5e-10 38.4 4.2 1.8e-09 37.5 4.2 1.5 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.16 EOO03971.1 - 0.14 11.9 0.1 0.45 10.3 0.0 1.9 2 0 0 2 2 2 0 CUE domain Adaptin_N PF01602.20 EOO03972.1 - 4e-122 408.4 7.5 5e-122 408.1 7.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EOO03972.1 - 2e-55 187.2 8.5 2.1e-55 187.2 0.1 3.4 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EOO03972.1 - 3.9e-17 62.4 6.3 2.3e-06 27.9 0.1 5.3 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 EOO03972.1 - 2.9e-11 42.6 5.2 0.00037 20.5 0.0 5.8 6 0 0 6 6 6 3 HEAT repeat RTP1_C1 PF10363.9 EOO03972.1 - 0.0011 19.2 0.9 0.18 12.0 0.0 3.5 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EOO03972.1 - 0.0014 18.2 1.7 0.73 9.4 0.0 3.3 3 1 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.6 EOO03972.1 - 0.0039 17.7 13.9 2.7 8.6 0.0 6.5 7 0 0 7 7 7 1 HEAT-like repeat Atx10homo_assoc PF09759.9 EOO03972.1 - 0.024 14.6 0.2 26 4.9 0.0 4.0 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EOO03972.1 - 0.13 12.4 4.2 6.6 6.9 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DNA_alkylation PF08713.11 EOO03972.1 - 0.13 11.9 0.1 11 5.6 0.0 3.2 2 2 1 3 3 3 0 DNA alkylation repair enzyme Mob1_phocein PF03637.17 EOO03973.1 - 7.1e-21 75.0 0.0 1.1e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 EOO03973.1 - 0.24 11.7 4.0 0.51 10.7 4.0 1.5 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases KR PF08659.10 EOO03974.1 - 2.9e-50 170.7 4.5 3.1e-32 111.9 0.3 2.7 1 1 1 2 2 2 2 KR domain ADH_zinc_N_2 PF13602.6 EOO03974.1 - 1.1e-18 68.5 0.0 3.9e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EOO03974.1 - 1e-15 57.9 0.0 2.8e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EOO03974.1 - 6.3e-10 39.3 0.1 1.8e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 EOO03974.1 - 2.8e-08 33.4 7.4 1.3e-05 24.8 0.2 3.5 2 1 1 3 3 3 2 short chain dehydrogenase ADH_N PF08240.12 EOO03974.1 - 6.7e-08 32.4 0.2 1.9e-07 30.9 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.15 EOO03974.1 - 0.01 15.0 0.4 0.029 13.5 0.2 1.9 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.13 EOO03974.1 - 0.025 14.1 1.0 0.87 9.1 0.1 2.4 2 0 0 2 2 2 0 NmrA-like family Epimerase PF01370.21 EOO03974.1 - 0.039 13.4 0.2 0.17 11.3 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 EOO03974.1 - 0.07 12.4 0.2 0.22 10.7 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EOO03974.1 - 0.088 13.4 0.0 0.27 11.8 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 EOO03974.1 - 0.093 12.1 0.1 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short_C2 PF13561.6 EOO03974.1 - 0.23 11.0 9.5 1.4 8.4 0.1 3.9 4 1 1 5 5 5 0 Enoyl-(Acyl carrier protein) reductase DEAD PF00270.29 EOO03975.1 - 4.8e-43 147.0 0.1 7.4e-43 146.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EOO03975.1 - 2.4e-19 69.7 0.0 8.7e-19 67.9 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EOO03975.1 - 7.6e-14 51.7 0.0 1.5e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EOO03975.1 - 1.8e-05 24.8 0.0 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DSPc PF00782.20 EOO03976.1 - 2e-12 47.1 0.0 1.4e-11 44.4 0.0 2.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EOO03976.1 - 0.01 16.1 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain polyprenyl_synt PF00348.17 EOO03976.1 - 0.031 13.3 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Polyprenyl synthetase Ribosomal_L23 PF00276.20 EOO03977.1 - 1.9e-10 41.0 0.0 3.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 La PF05383.17 EOO03979.1 - 2.7e-19 69.0 0.0 4.4e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EOO03979.1 - 3.9e-09 36.2 0.3 6.8e-09 35.4 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DnaJ PF00226.31 EOO03981.1 - 2.8e-14 53.0 2.5 4e-14 52.5 0.2 2.4 3 0 0 3 3 3 1 DnaJ domain ALMT PF11744.8 EOO03981.1 - 7.2 5.3 6.4 9.3 4.9 6.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Peptidase_S41 PF03572.18 EOO03984.1 - 1.5e-06 27.9 0.0 3.7e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 SKI PF01202.22 EOO03985.1 - 2.7e-20 73.1 0.1 6.7e-20 71.8 0.0 1.6 2 0 0 2 2 2 1 Shikimate kinase DHquinase_I PF01487.15 EOO03985.1 - 2.3e-15 57.5 0.0 4.5e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 EOO03985.1 - 1.1e-14 54.5 0.1 2.6e-14 53.2 0.1 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 EOO03985.1 - 1.2e-08 35.1 0.1 2.8e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 EOO03985.1 - 0.0024 17.6 0.0 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain F420_oxidored PF03807.17 EOO03985.1 - 0.06 13.9 0.1 0.2 12.3 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.18 EOO03986.1 - 6.3e-24 84.4 0.1 1.1e-23 83.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EOO03987.1 - 4.1e-29 101.6 34.2 4.1e-29 101.6 34.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Amidase PF01425.21 EOO03988.1 - 2.4e-13 49.9 0.0 2.7e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 Amidase Transp_cyt_pur PF02133.15 EOO03989.1 - 1.1e-14 54.1 7.7 1.3e-14 53.8 7.7 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NDUF_B12 PF08122.12 EOO03989.1 - 2.1 8.5 7.6 3 8.0 0.3 3.3 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Bud13 PF09736.9 EOO03990.1 - 4.7e-51 173.0 7.5 4.7e-51 173.0 7.5 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Cytadhesin_P30 PF07271.11 EOO03990.1 - 0.21 11.1 1.5 0.43 10.1 1.5 1.5 1 1 0 1 1 1 0 Cytadhesin P30/P32 Bac_rhamnosid6H PF17389.2 EOO03992.1 - 1.7e-83 280.7 4.6 2.4e-83 280.2 4.6 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 EOO03992.1 - 7.2e-09 35.3 0.0 1.4e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid PF05592.11 EOO03992.1 - 2.7e-07 30.5 0.0 4.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain RNA_ligase PF09414.10 EOO03993.1 - 2.9e-29 102.5 0.0 4.1e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 RNA ligase MFS_1 PF07690.16 EOO03995.1 - 5.8e-42 143.9 48.3 5.8e-42 143.9 48.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EOO03995.1 - 0.00012 20.7 22.9 0.00028 19.4 22.9 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) F-box-like PF12937.7 EOO03996.1 - 0.0059 16.5 0.0 0.0097 15.8 0.0 1.3 1 0 0 1 1 1 1 F-box-like Chitin_synth_1 PF01644.17 EOO03997.1 - 4.5e-78 260.9 0.2 6.9e-78 260.3 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EOO03997.1 - 1.2e-27 95.7 0.1 2.4e-27 94.7 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EOO03997.1 - 1.5e-23 83.3 3.7 6.3e-20 71.3 0.0 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EOO03997.1 - 2.5e-08 34.0 0.3 2.5e-08 34.0 0.3 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_hydro_125 PF06824.11 EOO03998.1 - 2e-172 573.8 0.0 2.3e-172 573.6 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Phosphoesterase PF04185.14 EOO03999.1 - 3.4e-32 112.0 0.6 2.5e-30 105.9 0.2 2.8 1 1 1 2 2 2 2 Phosphoesterase family DJ-1_PfpI PF01965.24 EOO04000.1 - 6.2e-14 52.1 0.0 1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EOO04000.1 - 0.00019 21.2 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like Haemocyan_bet_s PF14830.6 EOO04000.1 - 0.043 13.8 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Haemocyanin beta-sandwich Polysacc_deac_1 PF01522.21 EOO04001.1 - 4.1e-13 49.3 0.0 9.4e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EOO04001.1 - 0.032 13.9 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Peptidase_S28 PF05577.12 EOO04002.1 - 2.1e-47 161.9 0.1 1.5e-46 159.1 0.1 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 SET PF00856.28 EOO04003.1 - 2.3e-10 41.1 0.0 3.8e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 SET domain C1_2 PF03107.16 EOO04003.1 - 0.52 10.7 4.6 0.96 9.8 0.2 2.6 2 0 0 2 2 2 0 C1 domain NAD_binding_2 PF03446.15 EOO04004.1 - 8.5e-23 81.3 0.0 1.8e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EOO04004.1 - 9.5e-05 22.6 0.3 0.00026 21.2 0.3 1.7 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 EOO04004.1 - 0.00016 21.8 0.3 0.00034 20.7 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EOO04004.1 - 0.00032 21.2 0.3 0.0007 20.1 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 EOO04004.1 - 0.014 15.0 0.3 0.036 13.7 0.3 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amidase PF01425.21 EOO04004.1 - 0.033 13.2 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 Amidase Fungal_trans PF04082.18 EOO04005.1 - 2e-09 36.9 0.0 3.4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATG16 PF08614.11 EOO04006.1 - 0.018 15.2 1.7 0.018 15.2 1.7 2.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) FAM76 PF16046.5 EOO04006.1 - 0.071 12.5 9.0 0.027 13.8 4.1 2.2 2 0 0 2 2 2 0 FAM76 protein SOGA PF11365.8 EOO04006.1 - 0.11 13.6 1.6 0.26 12.5 0.4 2.2 2 0 0 2 2 2 0 Protein SOGA DUF5624 PF18538.1 EOO04006.1 - 0.13 12.3 0.1 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) KASH_CCD PF14662.6 EOO04006.1 - 0.68 9.7 10.4 0.019 14.8 4.0 1.6 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 EOO04006.1 - 2.1 8.4 11.3 2.8 8.0 3.2 2.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Ferrochelatase PF00762.19 EOO04008.1 - 1.1e-93 313.9 0.0 1.2e-93 313.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Nop53 PF07767.11 EOO04009.1 - 8e-113 377.8 33.0 1e-112 377.5 33.0 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Rrn6 PF10214.9 EOO04009.1 - 0.083 11.4 7.2 0.11 11.0 7.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Borrelia_P83 PF05262.11 EOO04009.1 - 0.36 9.3 19.0 0.49 8.8 19.0 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1515 PF07439.11 EOO04009.1 - 0.61 10.1 3.9 1.8 8.6 3.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) RNA_pol_Rpb8 PF03870.15 EOO04010.1 - 1.5e-46 158.0 0.0 1.7e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 EOO04010.1 - 6e-07 29.5 0.2 0.0032 17.5 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G MOSC PF03473.17 EOO04011.1 - 5.4e-12 45.9 0.0 8.7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EOO04011.1 - 7.4e-12 45.2 0.0 1.3e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain ThiF PF00899.21 EOO04012.1 - 1.5e-18 67.1 0.0 3.5e-18 65.9 0.0 1.6 1 1 0 1 1 1 1 ThiF family PTR2 PF00854.21 EOO04015.1 - 1.4e-47 162.4 0.5 1.9e-47 162.0 0.2 1.3 1 1 0 1 1 1 1 POT family Tetraspanin PF00335.20 EOO04015.1 - 1.8 8.2 4.9 0.94 9.1 1.1 2.2 2 0 0 2 2 2 0 Tetraspanin family WD40 PF00400.32 EOO04016.1 - 1.6e-13 50.9 4.0 0.0068 17.2 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO04016.1 - 0.00015 22.0 0.1 0.41 11.0 0.0 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain OPT PF03169.15 EOO04017.1 - 8.5e-124 414.4 44.9 9.7e-124 414.3 44.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein 2-Hacid_dh_C PF02826.19 EOO04019.1 - 6e-45 152.8 0.0 9.1e-45 152.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EOO04019.1 - 0.00017 21.2 0.0 0.00056 19.6 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ELFV_dehydrog PF00208.21 EOO04019.1 - 0.024 14.4 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AdoHcyase_NAD PF00670.21 EOO04019.1 - 0.029 14.5 0.0 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 EOO04019.1 - 0.034 14.6 0.0 0.09 13.2 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding OPT PF03169.15 EOO04020.1 - 9.8e-88 295.3 17.0 9.8e-88 295.3 17.0 1.9 1 1 1 2 2 2 2 OPT oligopeptide transporter protein TPR_16 PF13432.6 EOO04021.1 - 0.00026 21.6 0.1 0.011 16.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_16 PF13191.6 EOO04021.1 - 0.0024 18.3 0.0 0.022 15.1 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_26 PF13500.6 EOO04021.1 - 0.019 14.8 0.7 0.19 11.6 0.0 3.0 4 0 0 4 4 4 0 AAA domain TPR_2 PF07719.17 EOO04021.1 - 0.02 15.0 1.3 0.71 10.1 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EOO04021.1 - 0.026 15.1 7.4 0.88 10.4 0.6 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat EFP PF01132.20 EOO04021.1 - 0.084 12.9 0.1 0.31 11.1 0.1 2.0 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain TPR_17 PF13431.6 EOO04021.1 - 0.11 12.9 0.3 2.6 8.6 0.0 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat AAA_28 PF13521.6 EOO04021.1 - 0.13 12.5 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_7 PF13176.6 EOO04021.1 - 0.25 11.4 1.0 10 6.4 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EOO04021.1 - 0.31 11.4 4.4 5.2 7.4 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EOO04021.1 - 0.43 10.5 4.4 2.6 8.0 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EOO04021.1 - 0.48 11.4 3.9 20 6.3 0.0 4.8 4 1 1 5 5 4 0 Tetratricopeptide repeat Snf7 PF03357.21 EOO04022.1 - 4.2e-31 107.9 27.8 4.2e-31 107.9 27.8 2.0 1 1 1 2 2 2 1 Snf7 MG4 PF17789.1 EOO04022.1 - 0.14 12.3 0.7 0.38 10.9 0.7 1.7 1 0 0 1 1 1 0 Macroglobulin domain MG4 DUF3138 PF11336.8 EOO04022.1 - 1.3 7.5 17.7 0.026 13.2 7.6 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3138) Allexi_40kDa PF05549.11 EOO04022.1 - 1.7 8.1 8.7 4.4 6.7 8.7 1.8 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF4795 PF16043.5 EOO04022.1 - 8.5 5.9 27.7 25 4.4 27.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Sugar_tr PF00083.24 EOO04023.1 - 1.3e-115 386.9 27.5 1.5e-115 386.7 27.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO04023.1 - 1.6e-22 79.9 52.1 3.3e-20 72.3 24.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SecA_DEAD PF07517.14 EOO04023.1 - 0.22 10.8 0.3 0.36 10.1 0.3 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain Lipoxygenase PF00305.19 EOO04024.1 - 5.4e-24 84.6 0.4 2.1e-23 82.6 0.4 1.7 1 1 0 1 1 1 1 Lipoxygenase Polysacc_deac_1 PF01522.21 EOO04025.1 - 1.6e-10 41.0 0.0 2.7e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF3146 PF11344.8 EOO04025.1 - 0.053 13.2 0.1 0.37 10.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) GMC_oxred_C PF05199.13 EOO04026.1 - 2.6e-31 109.1 0.0 3.8e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase MFS_1 PF07690.16 EOO04027.1 - 1.4e-20 73.6 31.4 1.3e-13 50.6 13.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SpoIIIAC PF06686.11 EOO04027.1 - 0.18 12.0 1.6 0.91 9.7 1.6 2.3 1 0 0 1 1 1 0 Stage III sporulation protein AC/AD protein family Cyclin_C_2 PF16899.5 EOO04028.1 - 2.1e-38 130.9 0.1 3.6e-36 123.7 0.0 3.0 2 1 0 2 2 2 1 Cyclin C-terminal domain Sec23_helical PF04815.15 EOO04028.1 - 0.026 14.3 0.1 0.062 13.1 0.1 1.6 1 0 0 1 1 1 0 Sec23/Sec24 helical domain Cyclin_N PF00134.23 EOO04028.1 - 0.031 14.0 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain Beta-lactamase PF00144.24 EOO04029.1 - 0.012 14.9 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase MFS_1 PF07690.16 EOO04030.1 - 2.3e-37 128.8 30.9 2.3e-37 128.8 30.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 EOO04030.1 - 0.49 10.7 15.5 0.64 10.3 0.8 3.8 2 2 1 3 3 3 0 Domain of unknown function (DUF1772) DPM3 PF08285.11 EOO04030.1 - 1.5 9.1 4.6 13 6.1 2.4 3.4 3 1 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Pept_tRNA_hydro PF01195.19 EOO04031.1 - 3.1e-26 92.4 0.0 3.7e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase adh_short PF00106.25 EOO04032.1 - 4.6e-28 98.0 0.0 6.4e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO04032.1 - 8.4e-26 91.0 0.0 9.8e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO04032.1 - 0.0081 16.1 0.1 0.021 14.7 0.0 1.6 2 0 0 2 2 2 1 KR domain Sugar_tr PF00083.24 EOO04033.1 - 8.4e-28 97.4 20.6 1.1e-27 97.1 20.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO04033.1 - 1.9e-06 27.0 15.2 2.3e-06 26.8 15.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Dioxygenase_C PF00775.21 EOO04034.1 - 1.6e-09 37.5 0.1 2.5e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase GrpB PF04229.14 EOO04035.1 - 2.5e-51 174.0 0.0 2.9e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 GrpB protein DUF4448 PF14610.6 EOO04036.1 - 4.4e-36 124.4 0.0 7.2e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.10 EOO04036.1 - 1.1e-05 24.7 0.8 2.3e-05 23.7 0.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 EOO04036.1 - 0.12 12.1 0.5 0.82 9.5 0.0 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 CcmD PF04995.14 EOO04036.1 - 0.4 10.8 2.1 1.7 8.8 0.5 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) BAR PF03114.18 EOO04037.1 - 5.5e-61 206.2 2.2 7.2e-61 205.9 2.2 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 EOO04037.1 - 0.0031 18.2 1.6 0.021 15.5 0.0 2.8 3 1 1 4 4 4 1 CP12 domain SVIP PF15811.5 EOO04037.1 - 0.66 10.5 4.7 0.43 11.0 0.5 2.4 2 0 0 2 2 2 0 Small VCP/p97-interacting protein Peptidase_S8 PF00082.22 EOO04038.1 - 3.7e-14 52.7 0.0 6.6e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 EOO04038.1 - 5.7e-09 36.4 0.0 0.00039 20.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EOO04038.1 - 1.3e-07 32.0 0.0 0.036 14.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EOO04038.1 - 3.5e-07 30.4 0.0 0.013 15.9 0.0 4.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EOO04038.1 - 0.00014 22.0 0.0 1.7 9.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Atrophin-1 PF03154.15 EOO04038.1 - 7 4.8 10.3 11 4.1 10.3 1.2 1 0 0 1 1 1 0 Atrophin-1 family Adap_comp_sub PF00928.21 EOO04039.1 - 1.2e-84 283.8 0.0 1.5e-84 283.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EOO04039.1 - 3.7e-05 23.7 0.2 6.8e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Protoglobin PF11563.8 EOO04040.1 - 3e-38 131.2 0.0 3.8e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Protoglobin Bestrophin PF01062.21 EOO04041.1 - 1e-29 103.9 0.0 1.4e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PHO4 PF01384.20 EOO04041.1 - 0.033 13.2 0.1 0.052 12.6 0.1 1.4 1 1 0 1 1 1 0 Phosphate transporter family Jiraiya PF15038.6 EOO04041.1 - 0.61 9.5 4.0 0.28 10.6 1.4 1.6 2 0 0 2 2 2 0 Jiraiya FAA_hydrolase PF01557.18 EOO04042.1 - 5e-64 215.9 0.0 6.3e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.16 EOO04043.1 - 1.3e-15 57.2 54.8 4.3e-08 32.5 40.0 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF543 PF04418.12 EOO04043.1 - 0.27 11.3 1.6 1.1 9.3 1.6 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF543) F_bP_aldolase PF01116.20 EOO04044.1 - 4.7e-56 190.3 0.0 5.2e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MFS_1 PF07690.16 EOO04045.1 - 1.4e-32 113.0 26.8 1.4e-32 113.0 26.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Ammonium_transp PF00909.21 EOO04046.1 - 1e-117 393.2 27.3 1.2e-117 393.1 27.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TMEM107 PF14995.6 EOO04046.1 - 4.2 7.8 9.5 4.7 7.7 1.7 3.2 3 0 0 3 3 3 0 Transmembrane protein Glyco_hydro_6 PF01341.17 EOO04047.1 - 1.2e-105 353.7 2.9 1.6e-105 353.3 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 BAR PF03114.18 EOO04048.1 - 1.4e-55 188.5 7.1 1.6e-55 188.3 7.1 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 EOO04048.1 - 1.8e-06 27.3 2.2 1.9e-06 27.2 2.2 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF3086 PF11285.8 EOO04048.1 - 0.00014 21.1 1.1 0.00021 20.5 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3086) Arfaptin PF06456.13 EOO04048.1 - 0.0024 17.5 4.0 0.0032 17.1 4.0 1.3 1 0 0 1 1 1 1 Arfaptin-like domain PMEI PF04043.15 EOO04048.1 - 0.22 11.9 2.8 0.26 11.6 1.5 1.8 1 1 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor OmpH PF03938.14 EOO04048.1 - 0.73 10.2 9.3 0.75 10.1 5.1 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Aldo_ket_red PF00248.21 EOO04049.1 - 3.4e-64 216.9 0.0 4.6e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UQ_con PF00179.26 EOO04050.1 - 1.6e-28 99.1 0.0 3.3e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EOO04050.1 - 0.00023 21.0 0.0 0.0005 19.9 0.0 1.5 1 0 0 1 1 1 1 UEV domain IBR PF01485.21 EOO04050.1 - 0.0081 16.4 3.5 0.022 15.0 3.5 1.7 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zf-RING_7 PF02591.15 EOO04050.1 - 0.083 13.1 1.9 0.24 11.6 0.1 2.7 2 0 0 2 2 2 0 C4-type zinc ribbon domain Bclx_interact PF08945.10 EOO04050.1 - 0.11 12.3 0.3 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Bcl-x interacting, BH3 domain Auto_anti-p27 PF06677.12 EOO04050.1 - 0.16 12.2 0.0 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF4387 PF14330.6 EOO04051.1 - 1.5e-38 131.4 0.0 2.4e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 EOO04051.1 - 1.2e-14 53.8 0.0 1.6e-13 50.1 0.0 2.2 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA DUF2183 PF09949.9 EOO04052.1 - 3.5e-32 110.7 0.0 1.4e-31 108.7 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) GST_C_3 PF14497.6 EOO04053.1 - 6.5e-32 109.7 0.1 9.9e-32 109.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EOO04053.1 - 0.00035 20.7 0.0 0.00085 19.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EOO04053.1 - 0.0088 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EOO04053.1 - 0.018 15.4 0.0 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Sugar_tr PF00083.24 EOO04054.1 - 1.6e-80 271.2 30.9 1.8e-80 271.0 30.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO04054.1 - 1.3e-16 60.5 34.7 1.3e-16 60.5 34.7 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Folate_carrier PF01770.18 EOO04054.1 - 0.0014 17.4 0.7 0.0025 16.6 0.7 1.4 1 0 0 1 1 1 1 Reduced folate carrier DUF2574 PF10836.8 EOO04054.1 - 0.14 12.1 0.2 0.5 10.3 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) Amino_oxidase PF01593.24 EOO04055.1 - 1.4e-52 179.5 0.0 1.8e-52 179.2 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EOO04055.1 - 3.1e-09 36.9 0.0 1e-08 35.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EOO04055.1 - 8.4e-05 22.3 0.0 0.00022 21.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EOO04055.1 - 0.0026 16.9 0.0 0.0039 16.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EOO04055.1 - 0.009 15.3 0.0 0.02 14.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EOO04055.1 - 0.06 12.0 0.4 0.091 11.5 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 EOO04055.1 - 0.14 12.1 0.3 0.28 11.2 0.3 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding MFS_1 PF07690.16 EOO04056.1 - 1.1e-28 100.1 32.9 1.8e-28 99.5 32.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EOO04056.1 - 0.21 10.4 14.0 0.15 10.9 0.2 2.5 2 1 0 2 2 2 0 MFS_1 like family Sugar_tr PF00083.24 EOO04057.1 - 9e-78 262.1 23.3 1.1e-77 261.8 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO04057.1 - 2.5e-19 69.4 26.1 2.5e-19 69.4 26.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.7 EOO04057.1 - 1.7 8.8 30.0 2.6 8.2 3.6 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) RCC1_2 PF13540.6 EOO04059.1 - 0.0035 17.1 1.7 0.42 10.5 0.1 2.8 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat GSDH PF07995.11 EOO04059.1 - 0.017 14.5 1.6 0.11 11.8 1.6 2.5 2 1 0 2 2 2 0 Glucose / Sorbosone dehydrogenase NHL PF01436.21 EOO04059.1 - 0.054 13.6 0.1 1.3e+02 2.8 0.0 4.8 5 0 0 5 5 5 0 NHL repeat Ank_2 PF12796.7 EOO04060.1 - 1.4e-37 128.1 0.7 1.6e-13 51.1 1.4 3.9 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EOO04060.1 - 2.8e-34 117.1 1.6 1.2e-06 29.0 0.0 6.3 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EOO04060.1 - 3.6e-30 103.1 2.7 0.00034 20.9 0.0 7.7 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 EOO04060.1 - 2.7e-28 97.6 7.2 2.2e-08 34.2 0.6 5.5 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EOO04060.1 - 6.4e-24 81.4 3.7 0.041 14.4 0.0 7.9 7 1 0 7 7 7 7 Ankyrin repeat Formyl_trans_N PF00551.19 EOO04061.1 - 5.9e-38 130.4 0.0 7.3e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 EOO04061.1 - 3.7e-10 39.4 0.0 8.8e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 EOO04061.1 - 0.021 14.8 0.0 0.094 12.7 0.0 2.2 1 1 0 1 1 1 0 ACT domain AAA PF00004.29 EOO04062.1 - 0.0044 17.4 0.0 0.011 16.1 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IU_nuc_hydro PF01156.19 EOO04063.1 - 6.7e-69 232.8 0.0 7.7e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Peptidase_S64 PF08192.11 EOO04064.1 - 0.24 9.9 1.0 0.64 8.4 1.0 1.6 1 1 0 1 1 1 0 Peptidase family S64 RLAN PF14401.6 EOO04065.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain zinc_ribbon_16 PF17034.5 EOO04067.1 - 1.1e-15 57.9 2.8 2.2e-15 57.0 2.8 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 EOO04067.1 - 0.00014 21.4 2.0 0.00014 21.4 2.0 3.1 4 0 0 4 4 4 1 Zinc-ribbon, C4HC2 type DZR PF12773.7 EOO04067.1 - 4.2 7.5 5.4 36 4.5 3.7 2.8 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_2 PF13639.6 EOO04067.1 - 5.4 7.4 13.4 10 6.6 7.7 3.7 3 1 0 3 3 3 0 Ring finger domain DnaJ PF00226.31 EOO04068.1 - 1.4e-15 57.1 0.9 4.1e-15 55.7 0.9 1.8 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 EOO04068.1 - 3.8e-10 39.4 0.0 7.1e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DUF4512 PF14975.6 EOO04068.1 - 4.9 8.0 5.0 11 6.8 1.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4512) PAP2_3 PF14378.6 EOO04069.1 - 1.8e-26 93.0 16.1 1e-21 77.5 4.9 2.3 2 0 0 2 2 2 2 PAP2 superfamily PAP2_C PF14360.6 EOO04069.1 - 0.064 13.8 0.8 0.064 13.8 0.8 3.3 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Acetyltransf_7 PF13508.7 EOO04070.1 - 1e-05 25.8 0.0 3.2e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EOO04070.1 - 0.0003 21.0 0.0 0.0007 19.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EOO04070.1 - 0.0021 18.0 0.0 0.0073 16.2 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2347 PF09804.9 EOO04071.1 - 2.7e-89 299.5 0.0 1e-63 215.6 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 EOO04071.1 - 1.9e-51 175.1 4.2 1.9e-51 175.1 4.2 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4484) Peroxidase_2 PF01328.17 EOO04072.1 - 4.7e-11 43.6 0.1 5e-11 43.5 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Lectin_leg-like PF03388.13 EOO04073.1 - 9e-65 218.2 0.0 1.2e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 EOO04073.1 - 1.1e-06 28.8 0.2 1.6e-06 28.3 0.2 1.1 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 EOO04073.1 - 0.00016 21.3 0.0 0.4 10.2 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain Bac_luciferase PF00296.20 EOO04074.1 - 5.7e-54 183.7 0.2 7.6e-54 183.2 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Isochorismatase PF00857.20 EOO04074.1 - 1.3e-12 48.3 0.0 7.7e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 Isochorismatase family Hydantoinase_A PF01968.18 EOO04075.1 - 1.3e-93 313.4 1.0 1.9e-93 312.9 1.0 1.2 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydantoinase_B PF02538.14 EOO04075.1 - 1.1e-20 73.6 0.0 1.7e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydant_A_N PF05378.13 EOO04075.1 - 5.2e-12 45.8 0.8 2.3e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 EOO04075.1 - 0.12 10.9 1.8 0.15 10.6 0.1 2.0 3 0 0 3 3 3 0 MutL protein Hydrolase_like PF13242.6 EOO04076.1 - 1.9e-14 53.5 0.1 7.2e-14 51.6 0.1 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EOO04076.1 - 2.4e-14 53.3 0.0 4.9e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EOO04076.1 - 0.00049 20.4 0.0 0.012 15.9 0.0 1.9 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase p450 PF00067.22 EOO04077.1 - 1.5e-50 172.3 0.0 2e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hexokinase_1 PF00349.21 EOO04078.1 - 3.2e-32 112.1 0.0 3.6e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Hexokinase Inv-AAD PF18785.1 EOO04079.1 - 2.4e-57 192.4 0.0 2.8e-57 192.1 0.0 1.1 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EOO04079.1 - 3e-14 52.7 0.0 4.3e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 EOO04079.1 - 0.001 19.0 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain MafB19-deam PF14437.6 EOO04079.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.5 1 1 0 1 1 1 0 MafB19-like deaminase Acyltransferase PF01553.21 EOO04080.1 - 7.7e-33 113.0 0.0 1.2e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ribonuc_L-PSP PF01042.21 EOO04080.1 - 0.04 13.9 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Endoribonuclease L-PSP ABC2_membrane_3 PF12698.7 EOO04080.1 - 7.7 5.5 11.1 11 5.1 11.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Actin PF00022.19 EOO04081.1 - 2.5e-29 102.1 0.0 6.2e-18 64.6 0.0 2.5 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 EOO04081.1 - 1.1e-06 28.2 0.7 0.037 13.2 0.1 2.3 2 0 0 2 2 2 2 Putative actin-like family FtsA PF14450.6 EOO04081.1 - 0.015 15.7 0.0 0.087 13.3 0.0 2.2 2 1 0 2 2 2 0 Cell division protein FtsA MreB_Mbl PF06723.13 EOO04081.1 - 0.022 13.6 0.0 0.3 9.9 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Baculo_11_kDa PF06143.11 EOO04082.1 - 0.02 14.4 0.4 0.041 13.4 0.3 1.5 1 1 0 1 1 1 0 Baculovirus 11 kDa family DUF2235 PF09994.9 EOO04083.1 - 2.5e-46 158.3 0.0 3.4e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Afi1 PF07792.12 EOO04084.1 - 3.8e-50 169.8 3.9 6.5e-50 169.1 3.9 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 EOO04084.1 - 1.1e-36 125.3 0.0 2e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 EOO04084.1 - 1.1e-07 30.9 0.1 0.011 14.4 0.0 4.0 3 1 0 4 4 4 2 Transport protein Avl9 CNDH2_C PF16858.5 EOO04084.1 - 0.008 16.1 3.5 0.013 15.4 3.5 1.3 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF1168 PF06658.12 EOO04084.1 - 0.0097 15.7 14.3 0.021 14.7 14.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF2347 PF09804.9 EOO04084.1 - 0.015 14.9 0.0 0.1 12.2 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Astro_capsid_p PF12226.8 EOO04084.1 - 0.015 14.5 10.4 0.025 13.7 10.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein AP3D1 PF06375.11 EOO04084.1 - 0.021 15.1 9.8 0.048 13.9 9.8 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Nop53 PF07767.11 EOO04084.1 - 0.066 12.6 10.7 0.11 11.9 10.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PPP4R2 PF09184.11 EOO04084.1 - 0.075 12.6 14.7 0.012 15.3 10.8 1.6 2 0 0 2 2 2 0 PPP4R2 Nop14 PF04147.12 EOO04084.1 - 0.079 11.2 15.8 0.12 10.6 15.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 EOO04084.1 - 0.1 12.0 7.4 0.18 11.2 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Cwf_Cwc_15 PF04889.12 EOO04084.1 - 0.31 10.7 20.3 0.7 9.6 20.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 EOO04084.1 - 0.32 10.3 13.6 0.56 9.5 13.6 1.3 1 0 0 1 1 1 0 BUD22 DUF3295 PF11702.8 EOO04084.1 - 0.32 10.3 9.9 0.49 9.7 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) CSRNP_N PF16019.5 EOO04084.1 - 0.41 10.5 3.2 0.71 9.8 3.2 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus RXT2_N PF08595.11 EOO04084.1 - 0.91 9.5 10.3 1.8 8.5 10.3 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal PPL5 PF18168.1 EOO04084.1 - 2 7.6 6.9 3.2 7.0 6.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 RNA_pol_3_Rpc31 PF11705.8 EOO04084.1 - 2.2 8.5 23.5 3.8 7.7 23.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FYDLN_acid PF09538.10 EOO04084.1 - 7 7.4 21.4 14 6.4 21.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zip PF02535.22 EOO04085.1 - 2e-20 73.3 1.2 2.5e-20 73.0 1.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter ICMT PF04140.14 EOO04086.1 - 8.2e-28 96.7 1.1 8.2e-28 96.7 1.1 1.7 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EOO04086.1 - 4.1e-12 46.4 2.3 4.1e-12 46.4 2.3 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 EOO04086.1 - 0.00041 19.9 2.6 0.00041 19.9 2.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 EOO04086.1 - 1.5 8.2 18.9 0.22 11.0 12.1 2.1 1 1 1 2 2 2 0 NnrU protein Glyco_hydro_16 PF00722.21 EOO04087.1 - 2.3e-08 33.7 0.5 4.1e-08 32.9 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Esterase PF00756.20 EOO04088.1 - 1.1e-52 179.2 0.0 1.3e-52 178.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 EOO04088.1 - 6.4e-06 25.8 0.3 2.5e-05 23.9 0.2 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase Chlorophyllase2 PF12740.7 EOO04088.1 - 0.00033 19.6 0.0 0.0005 19.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EOO04088.1 - 0.0018 17.6 0.1 0.003 16.9 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EOO04088.1 - 0.014 14.9 0.1 0.025 14.0 0.1 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EOO04088.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 EOO04088.1 - 0.14 11.2 0.1 0.26 10.3 0.1 1.5 1 1 0 1 1 1 0 Chlorophyllase Mtc PF03820.17 EOO04090.1 - 9.6e-119 396.0 0.0 1.1e-118 395.9 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier SBF PF01758.16 EOO04090.1 - 0.092 12.4 1.3 0.17 11.5 0.2 1.9 2 0 0 2 2 2 0 Sodium Bile acid symporter family CorA PF01544.18 EOO04092.1 - 6.1e-08 32.3 1.0 6.1e-08 32.3 1.0 2.1 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 EOO04092.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-C2H2 PF00096.26 EOO04093.1 - 1e-32 110.8 58.2 0.0011 19.3 0.8 11.0 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EOO04093.1 - 1.8e-20 72.3 42.3 0.00031 21.0 0.2 9.7 9 1 0 9 9 9 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 EOO04093.1 - 5.7e-19 67.2 54.7 0.0038 17.9 1.0 11.1 11 0 0 11 11 11 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EOO04093.1 - 6.5e-10 39.0 29.8 0.014 15.7 0.6 9.1 11 0 0 11 11 11 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EOO04093.1 - 4.9e-08 33.1 32.7 0.022 15.1 0.3 8.8 10 0 0 10 10 10 4 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 EOO04093.1 - 1.7e-05 25.0 21.4 0.0053 17.0 3.1 5.0 4 1 2 6 6 6 3 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 EOO04093.1 - 0.00012 22.3 24.6 0.25 11.5 0.2 5.5 4 1 0 5 5 5 3 Aberrant zinc-finger FOXP-CC PF16159.5 EOO04093.1 - 0.001 19.6 31.4 0.38 11.4 0.1 8.2 5 3 3 8 8 8 2 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 EOO04093.1 - 0.0011 18.8 3.8 14 5.7 0.0 4.5 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 EOO04093.1 - 0.045 13.6 3.0 1.1 9.1 0.1 3.4 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf_Hakai PF18408.1 EOO04093.1 - 0.79 9.5 28.5 0.26 11.0 0.5 6.4 7 0 0 7 7 7 0 C2H2 Hakai zinc finger domain Zn-C2H2_12 PF18112.1 EOO04093.1 - 3.9 8.0 13.0 0.068 13.6 2.3 3.6 4 0 0 4 4 2 0 Autophagy receptor zinc finger-C2H2 domain MBOAT PF03062.19 EOO04094.1 - 1.9e-19 70.2 20.9 2.7e-19 69.7 20.9 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EOO04094.1 - 0.0034 17.6 2.1 0.013 15.7 2.1 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MFS_1 PF07690.16 EOO04096.1 - 2.1e-11 43.3 28.6 3.9e-10 39.2 16.2 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EOO04096.1 - 4.3e-09 35.4 6.9 3.5e-08 32.4 6.9 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2040 PF09745.9 EOO04097.1 - 1.3e-34 118.8 26.5 1.3e-34 118.8 26.5 4.0 3 2 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) KH_1 PF00013.29 EOO04099.1 - 7.3e-41 137.8 11.7 6.4e-16 57.9 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EOO04099.1 - 2.8e-09 36.7 11.4 0.0063 16.3 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EOO04099.1 - 9.8e-09 35.0 3.8 0.019 14.8 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EOO04099.1 - 4.9e-05 23.3 5.7 0.24 11.5 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 EOO04099.1 - 0.017 15.1 0.0 11 6.1 0.0 2.8 3 0 0 3 3 3 0 KH-like RNA-binding domain MFS_1 PF07690.16 EOO04100.1 - 1.1e-23 83.8 31.5 5.4e-12 45.3 5.6 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.8 EOO04100.1 - 2.7e-05 23.0 0.1 0.0016 17.2 0.0 2.6 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 EOO04100.1 - 0.00084 18.3 1.2 0.37 9.6 0.0 3.1 2 1 0 3 3 3 2 MFS_1 like family Hexapep_2 PF14602.6 EOO04102.1 - 1.5e-10 40.6 3.7 2.5e-10 39.9 3.7 1.4 1 0 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 EOO04102.1 - 2.5e-09 36.5 4.5 2.5e-09 36.5 4.5 1.9 2 0 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 EOO04102.1 - 2.4e-08 34.1 0.3 4.2e-08 33.3 0.3 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase AHJR-like PF18743.1 EOO04102.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 REase_AHJR-like F-box-like PF12937.7 EOO04103.1 - 3.4e-09 36.5 0.0 1.4e-08 34.5 0.0 2.1 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 EOO04103.1 - 9.3e-08 31.5 15.7 0.0084 16.1 0.0 7.5 9 0 0 9 9 9 3 Leucine Rich repeat F-box PF00646.33 EOO04103.1 - 2.1e-06 27.5 0.0 7.2e-06 25.7 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 EOO04103.1 - 1.2e-05 25.5 11.4 0.04 14.4 0.1 5.4 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EOO04103.1 - 0.0046 17.3 10.3 0.46 11.2 0.1 6.5 7 0 0 7 7 7 1 Leucine Rich Repeat PRANC PF09372.10 EOO04103.1 - 0.014 15.7 0.1 0.044 14.1 0.0 1.8 2 0 0 2 2 2 0 PRANC domain MRC1 PF09444.10 EOO04103.1 - 0.067 13.7 1.9 0.12 12.8 1.9 1.3 1 0 0 1 1 1 0 MRC1-like domain p47_phox_C PF08944.11 EOO04103.1 - 0.081 12.4 0.1 0.21 11.0 0.1 1.7 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain SET PF00856.28 EOO04104.1 - 3.3e-10 40.6 0.0 7.2e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 SET domain Stm1_N PF09598.10 EOO04105.1 - 3.9e-06 27.6 4.8 3.9e-06 27.6 4.8 5.0 5 2 0 5 5 5 1 Stm1 HemX PF04375.14 EOO04105.1 - 0.11 11.7 0.6 0.16 11.2 0.6 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Lactamase_B_4 PF13691.6 EOO04106.1 - 1.6e-27 95.0 0.1 6.5e-27 93.0 0.0 2.1 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EOO04106.1 - 3.8e-14 52.7 0.2 4.7e-13 49.1 0.2 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EOO04106.1 - 1.3e-06 28.6 0.2 3.2e-06 27.3 0.2 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Glucosamine_iso PF01182.20 EOO04107.1 - 8.8e-72 241.6 0.0 1e-71 241.4 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Iwr1 PF08574.10 EOO04108.1 - 8.4e-18 65.1 10.1 8.4e-18 65.1 10.1 2.7 2 1 1 3 3 3 1 Transcription factor Iwr1 Paramyxo_P PF01806.17 EOO04108.1 - 0.045 13.2 0.2 0.079 12.4 0.2 1.3 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region DUF4238 PF14022.6 EOO04110.1 - 7.1e-62 209.4 0.4 7.6e-62 209.3 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) CALM_bind PF16025.5 EOO04111.1 - 2.2 8.8 6.8 0.77 10.3 1.4 2.7 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding Gly_transf_sug PF04488.15 EOO04112.1 - 3.3e-18 66.1 0.0 5.8e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EOO04112.1 - 0.049 13.0 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 EOO04112.1 - 0.11 11.7 0.5 0.19 11.0 0.1 1.5 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DUF1206 PF06724.11 EOO04112.1 - 0.15 12.2 0.3 0.15 12.2 0.3 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) Tyrosinase PF00264.20 EOO04114.1 - 2e-46 159.0 0.0 2.3e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF5102 PF17104.5 EOO04115.1 - 4.4e-05 23.7 5.9 0.0015 18.6 0.6 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5102) MDMPI_N PF11716.8 EOO04115.1 - 2.1 9.1 12.7 0.05 14.3 4.4 2.5 3 0 0 3 3 3 0 Mycothiol maleylpyruvate isomerase N-terminal domain Pkinase PF00069.25 EOO04116.1 - 3.2e-59 200.4 0.0 4.6e-59 199.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO04116.1 - 6.7e-20 71.4 0.0 1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EOO04116.1 - 3.9e-07 29.7 0.0 7.3e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EOO04116.1 - 2.7e-05 23.6 0.1 4.6e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EOO04116.1 - 7.7e-05 21.8 0.1 0.00012 21.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EOO04116.1 - 0.0032 17.1 0.1 0.0088 15.7 0.1 1.7 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EOO04116.1 - 0.0058 16.6 0.5 0.033 14.1 0.3 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EOO04116.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EOO04116.1 - 0.17 10.9 0.1 0.29 10.1 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PI-PLC-X PF00388.19 EOO04117.1 - 8e-65 216.9 0.0 2.4e-64 215.3 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EOO04117.1 - 3.5e-43 146.6 0.0 9e-43 145.3 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain CENP-M PF11111.8 EOO04117.1 - 0.02 14.1 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Centromere protein M (CENP-M) DUF5545 PF17699.1 EOO04117.1 - 6.2 6.6 8.3 8.1 6.2 5.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5545) DUF4451 PF14616.6 EOO04118.1 - 3.4e-23 82.1 0.0 5.9e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Gelsolin PF00626.22 EOO04119.1 - 1.9e-11 43.7 0.1 4.1e-05 23.4 0.0 3.6 3 2 0 3 3 3 2 Gelsolin repeat MFS_1 PF07690.16 EOO04120.1 - 4.7e-42 144.2 43.0 4.7e-42 144.2 43.0 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO04120.1 - 1.7e-14 53.6 9.3 1.7e-14 53.6 9.3 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter FA_hydroxylase PF04116.13 EOO04122.1 - 2.8e-25 89.2 16.5 4.3e-25 88.6 13.9 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily AMPK1_CBM PF16561.5 EOO04123.1 - 2.5e-09 37.2 0.1 4.5e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF4124 PF13511.6 EOO04124.1 - 4.4 7.7 12.3 0.25 11.7 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4124) zf-Tim10_DDP PF02953.15 EOO04125.1 - 1.4e-21 75.8 1.4 2e-21 75.4 1.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 EOO04125.1 - 0.049 13.3 2.8 0.09 12.5 2.8 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF2116 PF09889.9 EOO04125.1 - 0.071 13.1 1.0 0.12 12.4 0.3 1.7 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DEAD PF00270.29 EOO04126.1 - 2.5e-28 99.0 0.0 4.4e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EOO04126.1 - 2.6e-20 72.8 0.1 5e-19 68.7 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO04126.1 - 1.7e-05 24.9 0.0 4.5e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4045 PF13254.6 EOO04127.1 - 2.7e-91 307.3 60.8 6.4e-53 180.9 35.4 4.2 2 1 1 3 3 3 2 Domain of unknown function (DUF4045) Pkinase PF00069.25 EOO04128.1 - 6.4e-75 251.9 0.0 7.4e-75 251.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO04128.1 - 1.3e-38 132.8 0.0 1.6e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EOO04128.1 - 2.6e-08 33.5 0.0 4.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Rad21_Rec8 PF04824.16 EOO04128.1 - 0.098 12.0 0.3 0.21 10.9 0.3 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein Seadorna_VP7 PF07387.11 EOO04128.1 - 0.15 11.1 0.0 0.4 9.7 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 DLH PF01738.18 EOO04129.1 - 0.001 18.7 0.2 0.0015 18.1 0.2 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family EF-hand_6 PF13405.6 EOO04130.1 - 2.4e-10 39.5 0.6 0.0009 19.0 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EOO04130.1 - 8.1e-09 34.4 1.0 0.0017 17.7 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EOO04130.1 - 1.4e-05 25.4 0.1 6e-05 23.4 0.1 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EOO04130.1 - 1.8e-05 24.0 3.7 0.06 12.9 0.5 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EOO04130.1 - 4e-05 23.4 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EOO04130.1 - 0.0028 17.9 0.0 2 8.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain DUF2789 PF10982.8 EOO04130.1 - 0.078 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) PHD PF00628.29 EOO04131.1 - 2.8e-09 36.7 7.8 4.5e-09 36.1 7.8 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EOO04131.1 - 0.078 12.5 3.1 0.12 11.9 3.1 1.3 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 EOO04131.1 - 0.78 9.7 4.2 1.6 8.7 4.2 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PGAP1 PF07819.13 EOO04132.1 - 1.5e-05 24.8 0.4 3e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 EOO04132.1 - 0.00041 19.9 0.1 0.0007 19.2 0.1 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EOO04132.1 - 0.017 15.7 0.0 0.02 15.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family LCAT PF02450.15 EOO04132.1 - 0.033 13.4 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Cutinase PF01083.22 EOO04132.1 - 0.1 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase Arf PF00025.21 EOO04133.1 - 1.4e-66 223.3 0.9 1.5e-66 223.1 0.9 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EOO04133.1 - 2.7e-12 46.9 0.1 3.9e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EOO04133.1 - 7.4e-12 45.1 1.0 7.1e-07 28.7 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EOO04133.1 - 1.1e-11 44.6 0.0 1.3e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EOO04133.1 - 1.5e-09 37.5 0.0 1.8e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EOO04133.1 - 5.5e-08 32.9 0.0 7.9e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EOO04133.1 - 4.2e-06 26.3 0.0 4.8e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EOO04133.1 - 0.00068 19.2 0.0 0.014 15.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 EOO04133.1 - 0.0079 16.1 0.2 0.09 12.7 0.0 2.0 2 0 0 2 2 2 1 NACHT domain FeoB_N PF02421.18 EOO04133.1 - 0.03 13.9 0.2 0.077 12.5 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 EOO04133.1 - 0.078 13.0 0.0 0.75 9.8 0.0 2.0 2 0 0 2 2 2 0 Dynamin family 6PF2K PF01591.18 EOO04133.1 - 0.12 11.6 0.1 0.29 10.4 0.0 1.7 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Fructosamin_kin PF03881.14 EOO04134.1 - 2.1e-21 76.4 0.0 2.4e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EOO04134.1 - 0.065 13.1 0.0 0.086 12.7 0.0 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family EcKinase PF02958.20 EOO04134.1 - 0.099 11.9 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase PTS_2-RNA PF01885.16 EOO04135.1 - 1.3e-65 220.9 0.0 1.5e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Spore_coat_CotO PF14153.6 EOO04136.1 - 0.052 13.5 18.4 0.078 12.9 18.4 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Presenilin PF01080.17 EOO04136.1 - 0.064 12.0 16.4 0.085 11.6 16.4 1.2 1 0 0 1 1 1 0 Presenilin CAF-1_p150 PF11600.8 EOO04136.1 - 0.13 12.0 41.9 0.26 11.0 41.9 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.12 EOO04136.1 - 0.32 10.8 23.2 0.52 10.1 23.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 EOO04136.1 - 0.42 8.5 10.3 0.58 8.0 10.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Smg8_Smg9 PF10220.9 EOO04136.1 - 0.49 8.6 12.8 0.66 8.2 12.8 1.1 1 0 0 1 1 1 0 Smg8_Smg9 DUF4776 PF16003.5 EOO04136.1 - 0.76 8.7 23.5 1.1 8.2 23.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) NPR3 PF03666.13 EOO04136.1 - 1.1 8.0 14.3 1.4 7.7 14.3 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MTBP_C PF14920.6 EOO04136.1 - 1.2 8.8 19.6 1.7 8.3 18.7 1.5 1 1 0 1 1 1 0 MDM2-binding Asp-B-Hydro_N PF05279.11 EOO04136.1 - 1.3 9.1 24.2 1.9 8.5 24.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Neur_chan_memb PF02932.16 EOO04136.1 - 1.8 8.6 9.7 2.4 8.1 9.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dsh_C PF12316.8 EOO04136.1 - 2 8.8 5.0 3.3 8.1 5.0 1.5 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal YabA PF06156.13 EOO04136.1 - 2.8 8.6 17.2 9.3 7.0 17.2 1.9 1 1 0 1 1 1 0 Initiation control protein YabA GREB1 PF15782.5 EOO04136.1 - 3.2 4.8 11.0 3.9 4.5 11.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ALMT PF11744.8 EOO04136.1 - 6.8 5.4 12.9 9.4 4.9 12.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CDH-cyt PF16010.5 EOO04137.1 - 1.2e-66 223.9 4.2 3.4e-66 222.4 2.8 2.2 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 EOO04137.1 - 1.5e-27 96.7 0.1 3.1e-27 95.7 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EOO04137.1 - 9e-24 84.6 0.3 1.7e-23 83.8 0.3 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EOO04137.1 - 1.3e-10 40.9 0.3 0.00017 20.8 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain CBM_1 PF00734.18 EOO04137.1 - 2.1e-09 37.2 11.9 7.2e-09 35.5 11.9 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain DAO PF01266.24 EOO04137.1 - 0.00012 21.8 0.1 0.0015 18.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EOO04137.1 - 0.0002 21.5 0.0 0.00062 20.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EOO04137.1 - 0.00026 20.5 0.0 0.03 13.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase DOMON PF03351.17 EOO04137.1 - 0.00028 21.1 0.1 0.00093 19.4 0.1 1.9 1 0 0 1 1 1 1 DOMON domain HI0933_like PF03486.14 EOO04137.1 - 0.00057 18.7 0.0 0.0014 17.4 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 EOO04137.1 - 0.0014 19.2 0.1 0.23 12.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EOO04137.1 - 0.0014 17.9 0.1 0.004 16.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EOO04137.1 - 0.0092 15.3 1.1 0.055 12.7 0.9 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EOO04137.1 - 0.04 13.0 0.1 0.062 12.3 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 EOO04137.1 - 0.077 12.2 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EOO04137.1 - 0.16 11.2 0.8 0.84 8.8 0.3 2.1 2 0 0 2 2 2 0 Thi4 family TPR_1 PF00515.28 EOO04138.1 - 7.3e-47 155.4 15.7 5.3e-10 38.7 0.1 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 EOO04138.1 - 3.3e-43 142.3 17.6 4.5e-07 29.5 0.0 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 EOO04138.1 - 1.2e-31 108.1 16.8 4.7e-08 32.6 0.6 7.4 6 2 2 8 8 8 5 TPR repeat DnaJ PF00226.31 EOO04138.1 - 6.7e-27 93.4 5.6 1.6e-26 92.2 4.1 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_8 PF13181.6 EOO04138.1 - 1.3e-25 87.4 12.4 1.3e-05 25.0 0.2 7.2 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 EOO04138.1 - 3.8e-25 88.3 11.0 1.4e-06 28.9 0.1 6.4 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 EOO04138.1 - 2.7e-22 79.0 22.3 4.5e-08 33.5 0.5 6.5 4 3 2 6 6 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 EOO04138.1 - 2.7e-20 71.2 16.3 0.00077 19.7 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 EOO04138.1 - 5.5e-19 67.2 24.1 3.1e-05 24.4 0.1 9.0 4 4 7 11 11 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 EOO04138.1 - 5.6e-17 60.5 5.5 0.14 12.2 0.0 7.1 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 EOO04138.1 - 8e-16 58.1 24.3 0.0031 17.8 1.3 7.8 4 4 5 9 9 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EOO04138.1 - 1.5e-14 54.0 9.5 2.8e-05 24.2 1.4 4.4 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EOO04138.1 - 1.4e-12 47.6 16.6 0.0031 17.6 1.5 6.8 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_15 PF13429.6 EOO04138.1 - 1.3e-10 41.0 14.4 0.00012 21.4 0.4 4.6 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 EOO04138.1 - 5.3e-10 39.3 25.0 0.047 14.3 0.0 8.4 10 0 0 10 10 7 4 Tetratricopeptide repeat TPR_10 PF13374.6 EOO04138.1 - 7e-07 28.9 22.6 0.048 13.5 0.1 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat BTAD PF03704.17 EOO04138.1 - 4.2e-05 24.0 11.3 0.38 11.2 0.5 4.6 2 1 1 3 3 3 3 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 EOO04138.1 - 6.7e-05 22.9 8.6 0.41 10.8 0.1 5.6 4 2 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 EOO04138.1 - 0.00014 21.0 3.0 0.0008 18.5 0.1 2.7 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 EOO04138.1 - 0.00064 20.0 17.8 0.22 11.8 0.1 5.0 3 3 1 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 EOO04138.1 - 0.001 18.1 5.3 0.059 12.3 0.7 3.0 2 1 0 3 3 3 2 NMDA receptor-regulated protein 1 Alkyl_sulf_dimr PF14863.6 EOO04138.1 - 0.0018 18.7 3.7 1 9.8 0.1 4.0 2 1 1 3 3 3 1 Alkyl sulfatase dimerisation SRP_TPR_like PF17004.5 EOO04138.1 - 0.004 17.2 5.8 0.21 11.6 0.6 3.9 4 1 0 4 4 3 1 Putative TPR-like repeat TPR_4 PF07721.14 EOO04138.1 - 0.011 16.3 7.2 0.038 14.6 0.0 4.3 5 0 0 5 5 2 0 Tetratricopeptide repeat DUF627 PF04781.12 EOO04138.1 - 0.018 15.0 7.8 0.13 12.3 1.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF627) SHNi-TPR PF10516.9 EOO04138.1 - 0.024 14.1 5.3 0.33 10.4 0.0 4.2 5 0 0 5 5 5 0 SHNi-TPR Coatomer_E PF04733.14 EOO04138.1 - 0.038 13.4 0.6 3.1 7.1 0.0 2.9 3 0 0 3 3 3 0 Coatomer epsilon subunit MAS20 PF02064.15 EOO04138.1 - 1.5 9.0 5.6 2.8 8.1 0.0 3.8 2 2 3 5 5 4 0 MAS20 protein import receptor MIT PF04212.18 EOO04138.1 - 1.7 8.8 17.4 4.3 7.5 0.5 5.1 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain DUF982 PF06169.12 EOO04138.1 - 2.3 8.3 6.4 6.4 6.9 0.2 3.4 4 0 0 4 4 3 0 Protein of unknown function (DUF982) UAA PF08449.11 EOO04139.1 - 2.3e-46 158.4 9.0 2.9e-46 158.1 9.0 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EOO04139.1 - 8.4e-06 26.0 31.9 4.1e-05 23.8 10.6 3.6 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EOO04139.1 - 0.0001 21.6 3.6 0.13 11.4 0.2 2.4 3 0 0 3 3 3 2 Nucleotide-sugar transporter TPT PF03151.16 EOO04139.1 - 0.0013 18.2 6.5 0.056 12.8 1.6 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family RNA_pol_Rpb6 PF01192.22 EOO04140.1 - 1.1e-17 63.7 0.2 1.8e-17 63.0 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pox_RNA_Pol_19 PF05320.12 EOO04140.1 - 0.16 11.9 2.3 0.33 10.9 2.3 1.5 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit RabGAP-TBC PF00566.18 EOO04141.1 - 4e-28 98.6 0.2 6.1e-28 98.0 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 EOO04142.1 - 1.5e-09 37.6 0.0 2.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO04142.1 - 0.0011 18.3 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Macoilin PF09726.9 EOO04142.1 - 0.19 10.2 1.7 0.24 9.9 1.7 1.1 1 0 0 1 1 1 0 Macoilin family Endonuclease_NS PF01223.23 EOO04143.1 - 1.3e-65 221.4 0.0 1.8e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Med10 PF09748.9 EOO04144.1 - 3.3e-48 162.6 0.0 3.8e-48 162.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PS_Dcarbxylase PF02666.15 EOO04145.1 - 1.8e-57 194.2 0.0 2.7e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EOO04145.1 - 1.7e-39 134.3 0.0 9.4e-19 67.6 0.0 2.4 2 0 0 2 2 2 2 C2 domain EF-hand_5 PF13202.6 EOO04145.1 - 0.0099 15.3 0.0 0.04 13.4 0.0 2.1 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EOO04145.1 - 0.015 14.8 0.4 0.045 13.3 0.0 2.1 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 EOO04145.1 - 0.017 15.0 0.5 0.07 13.1 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 EOO04145.1 - 0.032 14.7 0.2 0.11 13.0 0.2 1.9 1 0 0 1 1 1 0 EF-hand domain pair Inhibitor_I53 PF11714.8 EOO04145.1 - 2.7 8.2 4.5 7.2 6.9 4.5 1.7 1 0 0 1 1 1 0 Thrombin inhibitor Madanin SCP2 PF02036.17 EOO04146.1 - 6.6e-25 87.5 0.7 8.3e-25 87.2 0.7 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EOO04146.1 - 1.3e-06 28.7 0.3 1.6e-06 28.4 0.3 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 EOO04146.1 - 0.0018 18.7 0.1 0.0023 18.3 0.1 1.2 1 0 0 1 1 1 1 Sterol carrier protein domain FCH PF00611.23 EOO04148.1 - 3.2e-25 88.2 3.6 1.4e-24 86.2 0.0 2.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 EOO04148.1 - 7.3e-22 77.0 0.4 6.6e-13 48.3 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 EOO04148.1 - 8.6e-16 57.6 5.0 1.3e-15 57.0 5.0 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 EOO04148.1 - 8.6e-13 47.7 0.1 7e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.11 EOO04148.1 - 0.0012 19.1 0.4 0.23 11.8 0.1 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_2 PF07653.17 EOO04148.1 - 0.0042 16.7 0.1 2.7 7.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain C1_2 PF03107.16 EOO04148.1 - 0.0093 16.3 4.8 0.016 15.5 4.8 1.3 1 0 0 1 1 1 1 C1 domain Allexi_40kDa PF05549.11 EOO04148.1 - 0.064 12.8 4.8 0.38 10.2 0.1 2.5 2 0 0 2 2 2 0 Allexivirus 40kDa protein SH3_10 PF17902.1 EOO04148.1 - 0.16 12.1 0.1 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 SH3 domain KASH_CCD PF14662.6 EOO04148.1 - 0.95 9.3 14.1 0.096 12.5 7.5 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Tup_N PF08581.10 EOO04148.1 - 1.1 9.6 12.5 9 6.7 6.9 3.0 1 1 1 2 2 2 0 Tup N-terminal LETM1 PF07766.13 EOO04148.1 - 4 6.7 10.1 0.7 9.2 0.3 2.5 1 1 0 2 2 2 0 LETM1-like protein CDC50 PF03381.15 EOO04149.1 - 0.12 11.8 0.1 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Coatomer_E PF04733.14 EOO04150.1 - 3e-63 213.9 4.1 3.5e-63 213.7 4.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 EOO04150.1 - 9.1e-11 42.1 16.6 0.00059 20.3 1.8 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EOO04150.1 - 4.4e-07 30.0 0.6 0.73 10.1 0.0 3.4 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EOO04150.1 - 4.9e-06 26.0 1.6 0.025 13.8 1.6 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EOO04150.1 - 9.4e-05 22.9 11.9 0.0036 18.0 0.6 5.2 6 1 0 6 6 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EOO04150.1 - 0.00034 20.8 11.1 0.042 14.1 0.8 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EOO04150.1 - 0.00056 20.4 1.9 0.33 11.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EOO04150.1 - 0.0006 19.8 0.5 1.4 9.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EOO04150.1 - 0.0021 17.8 2.0 0.24 11.3 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EOO04150.1 - 0.0029 17.6 11.7 0.01 15.9 0.1 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TRIF-NTD PF17798.1 EOO04150.1 - 0.0059 16.7 3.3 0.2 11.8 1.0 2.3 2 0 0 2 2 2 1 TRIF N-terminal domain TPR_16 PF13432.6 EOO04150.1 - 0.015 15.9 14.8 0.19 12.4 1.4 4.4 3 1 3 6 6 5 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 EOO04150.1 - 0.017 15.2 2.2 1.4 9.0 0.1 3.4 1 1 1 3 3 3 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_17 PF13431.6 EOO04150.1 - 0.022 15.1 0.0 52 4.5 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EOO04150.1 - 0.027 15.1 2.5 0.12 13.1 0.7 4.9 7 1 0 7 7 5 0 Tetratricopeptide repeat Smr PF01713.21 EOO04150.1 - 0.043 14.2 0.0 0.26 11.7 0.0 2.2 2 0 0 2 2 2 0 Smr domain ANAPC5 PF12862.7 EOO04150.1 - 0.3 11.2 2.4 63 3.7 0.1 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_11 PF13414.6 EOO04150.1 - 0.3 10.8 5.0 0.39 10.5 0.7 3.4 4 0 0 4 4 4 0 TPR repeat TPR_9 PF13371.6 EOO04150.1 - 0.92 9.7 5.8 1.2 9.4 0.2 3.1 3 1 0 3 3 2 0 Tetratricopeptide repeat DJ-1_PfpI PF01965.24 EOO04151.1 - 1.7e-05 24.7 0.0 9.1e-05 22.3 0.0 2.2 1 1 0 1 1 1 1 DJ-1/PfpI family Transp_cyt_pur PF02133.15 EOO04154.1 - 1.7e-88 297.3 34.7 2.1e-88 297.0 34.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DEAD PF00270.29 EOO04155.1 - 1.2e-31 109.8 0.0 2.4e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EOO04155.1 - 5.6e-25 87.8 0.0 1.1e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EOO04155.1 - 9.9e-05 22.1 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EOO04155.1 - 0.00061 19.8 0.0 0.0018 18.3 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2999 PF11212.8 EOO04155.1 - 0.018 15.3 0.1 0.062 13.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) CMS1 PF14617.6 EOO04155.1 - 0.025 13.9 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 EOO04155.1 - 0.043 14.1 0.1 0.23 11.8 0.1 2.2 2 1 1 3 3 3 0 AAA domain AAA_22 PF13401.6 EOO04155.1 - 0.22 11.8 2.1 5.1 7.4 1.6 2.9 2 1 0 2 2 2 0 AAA domain DUF202 PF02656.15 EOO04156.1 - 0.52 10.8 8.2 19 5.8 8.2 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) MFS_1 PF07690.16 EOO04156.1 - 0.53 9.2 10.7 1.4 7.7 10.7 1.6 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF5353 PF17304.2 EOO04156.1 - 2.7 7.8 5.7 0.37 10.6 1.5 1.8 2 1 0 2 2 2 0 Family of unknown function (DUF5353) DUF485 PF04341.12 EOO04156.1 - 2.7 8.0 5.8 1.3 9.0 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF485 CDC50 PF03381.15 EOO04157.1 - 1.6e-98 329.6 0.6 2.1e-98 329.3 0.6 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Sirohm_synth_C PF14823.6 EOO04158.1 - 0.045 13.4 0.0 7.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal Glyco_hydro_72 PF03198.14 EOO04159.1 - 1e-123 412.6 5.8 1.2e-123 412.4 5.8 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EOO04159.1 - 2.5e-08 33.7 1.3 3e-07 30.1 1.3 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3280 PF11684.8 EOO04159.1 - 0.18 12.2 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2380) BCAS2 PF05700.11 EOO04161.1 - 5.5e-60 202.6 1.3 6.1e-60 202.4 1.3 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) cNMP_binding PF00027.29 EOO04162.1 - 1.3e-38 130.9 0.0 8.6e-20 70.6 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Methyltransf_23 PF13489.6 EOO04163.1 - 3.4e-07 30.2 0.0 5.6e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EOO04163.1 - 5.1e-05 23.8 0.0 0.00057 20.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO04163.1 - 0.0015 19.2 0.0 0.003 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO04163.1 - 0.096 13.4 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EOO04163.1 - 0.21 11.4 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pectate_lyase_3 PF12708.7 EOO04164.1 - 1.3e-47 162.4 12.9 2.1e-41 142.1 8.4 2.8 2 0 0 2 2 2 2 Pectate lyase superfamily protein HAD PF12710.7 EOO04165.1 - 2.8e-21 76.8 0.0 4.1e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EOO04165.1 - 0.0059 16.0 0.0 0.032 13.6 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.26 EOO04165.1 - 0.027 14.8 0.1 0.064 13.5 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 EOO04165.1 - 0.11 11.9 0.0 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Aldedh PF00171.22 EOO04166.1 - 7.4e-110 367.6 0.2 8.3e-110 367.4 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family EamA PF00892.20 EOO04167.1 - 4.9e-09 36.5 28.8 3e-06 27.5 0.7 2.7 3 0 0 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 EOO04167.1 - 3.6e-07 29.5 12.7 1.9e-05 23.8 2.1 2.6 3 1 0 3 3 3 2 Ceramide synthase regulator Nuc_sug_transp PF04142.15 EOO04167.1 - 0.051 12.7 4.8 0.77 8.9 0.0 2.1 2 0 0 2 2 2 0 Nucleotide-sugar transporter Cu_amine_oxid PF01179.20 EOO04168.1 - 1.8e-135 452.0 0.1 4e-134 447.6 0.1 2.0 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 EOO04168.1 - 1.7e-08 34.5 0.2 4.9e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain ODC_AZ PF02100.17 EOO04169.1 - 1.8e-43 147.1 0.0 2.2e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme EGF_Tenascin PF18720.1 EOO04169.1 - 0.17 11.9 0.5 1.2 9.3 0.1 2.2 2 0 0 2 2 2 0 Tenascin EGF domain Vir_act_alpha_C PF10400.9 EOO04170.1 - 1.1 10.0 4.2 2.3 8.9 4.2 1.4 1 0 0 1 1 1 0 Virulence activator alpha C-term Mod_r PF07200.13 EOO04170.1 - 5 7.2 10.6 11 6.1 10.6 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Oxidored_FMN PF00724.20 EOO04171.1 - 3.9e-38 131.6 0.0 5.3e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HTH_7 PF02796.15 EOO04171.1 - 0.019 15.0 0.1 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Dus PF01207.17 EOO04171.1 - 0.024 13.7 0.1 0.068 12.2 0.0 1.8 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Ribosomal_S24e PF01282.19 EOO04172.1 - 1.7e-36 124.0 0.1 3.1e-36 123.2 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e FAD_binding_3 PF01494.19 EOO04173.1 - 5.2e-15 55.5 1.1 2.4e-08 33.6 0.1 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EOO04173.1 - 5.8e-12 45.4 0.2 8e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EOO04173.1 - 4.1e-09 36.5 0.4 6.4e-05 22.7 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EOO04173.1 - 5.3e-08 32.0 0.6 2.7e-05 23.1 0.4 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EOO04173.1 - 1.6e-07 30.7 0.4 6.5e-07 28.8 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EOO04173.1 - 3.7e-06 27.1 0.1 1.2e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EOO04173.1 - 3.8e-06 26.2 0.1 3.3e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EOO04173.1 - 8.9e-06 25.3 0.4 2.5e-05 23.8 0.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EOO04173.1 - 1.9e-05 25.2 0.3 0.0033 17.9 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EOO04173.1 - 5.3e-05 22.2 0.3 0.19 10.5 0.2 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 EOO04173.1 - 5.7e-05 22.5 0.2 0.0009 18.6 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EOO04173.1 - 0.00084 18.5 0.1 0.036 13.1 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EOO04173.1 - 0.0056 16.0 0.0 0.0099 15.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EOO04173.1 - 0.039 13.9 0.4 8.6 6.3 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 EOO04173.1 - 0.045 13.0 0.0 5.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 EOO04173.1 - 0.066 12.4 0.3 0.13 11.5 0.3 1.4 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 EOO04173.1 - 0.18 11.7 0.1 0.31 10.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ABC2_membrane PF01061.24 EOO04175.1 - 1.6e-87 292.4 44.8 9.5e-50 168.9 16.9 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EOO04175.1 - 1.1e-23 84.3 0.0 3.6e-16 59.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EOO04175.1 - 4.6e-07 29.3 40.1 0.00011 21.5 17.3 2.8 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 EOO04175.1 - 0.00017 22.0 0.2 0.00031 21.2 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EOO04175.1 - 0.00055 19.9 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EOO04175.1 - 0.0073 16.0 0.1 0.023 14.5 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EOO04175.1 - 0.044 13.6 0.0 5.5 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EOO04175.1 - 0.057 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EOO04175.1 - 0.076 12.4 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EOO04175.1 - 0.12 12.6 0.0 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF1325 PF07039.11 EOO04176.1 - 2.8e-36 124.5 0.1 5.1e-36 123.7 0.1 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.10 EOO04176.1 - 0.037 13.8 0.0 0.44 10.4 0.0 2.3 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain Tudor_3 PF18115.1 EOO04176.1 - 0.051 13.4 0.0 0.58 10.0 0.0 2.4 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain SLX9 PF15341.6 EOO04176.1 - 0.75 10.2 3.6 1.3 9.4 3.0 1.6 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 adh_short PF00106.25 EOO04177.1 - 2.7e-36 124.9 0.0 3.6e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO04177.1 - 1.4e-19 70.6 0.0 1.9e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO04177.1 - 1.7e-12 47.6 0.0 4.3e-12 46.3 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EOO04177.1 - 0.00011 21.7 0.2 0.00015 21.3 0.2 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EOO04177.1 - 0.0015 18.1 0.1 0.0029 17.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EOO04177.1 - 0.0016 18.9 0.0 0.0046 17.5 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 EOO04177.1 - 0.0024 17.8 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EOO04177.1 - 0.0032 17.7 0.0 0.0054 17.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 EOO04177.1 - 0.052 12.6 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EOO04177.1 - 0.17 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Peptidase_M20 PF01546.28 EOO04178.1 - 3.7e-34 118.2 0.1 5e-34 117.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EOO04178.1 - 4.9e-13 49.0 0.0 9e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Pkinase PF00069.25 EOO04179.1 - 6.2e-69 232.3 0.0 7.5e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO04179.1 - 1.2e-31 110.0 0.0 1.6e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EOO04179.1 - 0.0088 15.0 0.0 0.017 14.1 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EOO04179.1 - 0.044 13.1 0.1 0.089 12.1 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EOO04179.1 - 0.062 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Actin PF00022.19 EOO04180.1 - 5.7e-113 377.6 0.0 3.9e-112 374.8 0.0 1.8 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 EOO04180.1 - 0.015 14.5 0.1 0.084 12.0 0.0 1.9 2 0 0 2 2 2 0 Putative actin-like family MreB_Mbl PF06723.13 EOO04180.1 - 0.033 13.0 0.0 0.23 10.2 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein DUF3455 PF11937.8 EOO04182.1 - 5.2e-33 114.7 0.0 9.8e-33 113.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3455) HATPase_c PF02518.26 EOO04183.1 - 1.3e-26 93.3 0.0 2.9e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EOO04183.1 - 1.6e-26 92.7 0.1 3.3e-26 91.6 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EOO04183.1 - 1.3e-16 60.3 0.1 3e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EOO04183.1 - 2.5e-11 43.7 0.0 5.1e-10 39.5 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EOO04183.1 - 1.2e-07 31.7 0.0 1.9e-06 27.9 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EOO04183.1 - 1.9e-06 28.1 0.0 0.008 16.4 0.0 2.7 3 0 0 3 3 3 2 PAS fold FR47 PF08445.10 EOO04183.1 - 0.052 13.5 0.3 4.5 7.3 0.1 2.6 2 0 0 2 2 2 0 FR47-like protein NDUF_B7 PF05676.13 EOO04184.1 - 1.6e-30 104.6 4.5 1.9e-30 104.4 4.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) AA_permease PF00324.21 EOO04185.1 - 4.7e-122 408.0 40.2 5.6e-122 407.7 40.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EOO04185.1 - 1.2e-29 103.4 44.6 1.6e-29 103.0 44.5 1.2 1 1 0 1 1 1 1 Amino acid permease Hexapep PF00132.24 EOO04186.1 - 4.5e-07 29.3 8.1 0.00063 19.4 2.0 4.4 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EOO04186.1 - 0.0018 18.0 0.8 0.6 9.9 0.1 2.9 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EOO04186.1 - 0.07 12.1 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase NPP1 PF05630.11 EOO04187.1 - 1.7e-68 230.6 0.0 1.9e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) 4HBT_2 PF13279.6 EOO04188.1 - 0.0044 17.5 0.0 0.0068 16.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Voltage_CLC PF00654.20 EOO04189.1 - 8.8e-89 298.2 12.8 1.2e-88 297.8 12.8 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 EOO04189.1 - 0.0023 18.4 0.0 0.018 15.5 0.0 2.2 2 0 0 2 2 2 1 CBS domain LacI PF00356.21 EOO04189.1 - 0.14 12.0 0.3 0.32 10.8 0.3 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Amidase PF01425.21 EOO04190.1 - 7.7e-79 265.7 0.0 1.4e-78 264.9 0.0 1.4 1 1 0 1 1 1 1 Amidase zf-HC2 PF13490.6 EOO04190.1 - 0.056 13.7 0.5 0.15 12.4 0.1 1.9 2 0 0 2 2 2 0 Putative zinc-finger Glyco_hydro_3 PF00933.21 EOO04191.1 - 1.1e-44 153.1 0.0 1.8e-44 152.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EOO04191.1 - 9.1e-43 146.6 0.0 1.3e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EOO04191.1 - 1.4e-15 57.2 0.4 3.9e-15 55.7 0.1 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 EOO04191.1 - 9.4e-09 35.2 0.8 2.8e-08 33.7 0.8 1.8 1 0 0 1 1 1 1 PA14 domain RSN1_7TM PF02714.15 EOO04192.1 - 3.2e-44 151.3 3.5 3.2e-44 151.3 3.5 1.5 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 EOO04192.1 - 3.6e-28 97.6 0.3 6.6e-28 96.7 0.3 1.4 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Kinocilin PF15033.6 EOO04194.1 - 0.042 13.5 0.1 0.096 12.3 0.1 1.5 1 0 0 1 1 1 0 Kinocilin protein Colicin_V PF02674.16 EOO04194.1 - 0.37 10.8 5.8 2.9 7.9 0.4 3.0 3 1 0 3 3 3 0 Colicin V production protein Aldo_ket_red PF00248.21 EOO04195.1 - 5.3e-36 124.3 0.0 7.6e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.13 EOO04196.1 - 2e-30 106.1 0.1 2.8e-30 105.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO04196.1 - 1.1e-25 90.6 0.3 2.3e-25 89.5 0.3 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EOO04196.1 - 3.9e-05 23.2 0.4 0.00018 21.0 0.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EOO04196.1 - 0.00011 21.4 1.4 0.00024 20.3 1.4 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Peptidase_M28 PF04389.17 EOO04197.1 - 9.4e-39 133.2 0.0 1.5e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EOO04197.1 - 3.9e-09 36.4 0.0 1.1e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EOO04197.1 - 3.3e-05 23.7 0.0 5.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 MFS_1 PF07690.16 EOO04198.1 - 2.8e-14 52.8 19.1 3.9e-14 52.4 19.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EOO04198.1 - 3.7e-10 39.3 9.2 7.3e-10 38.3 5.4 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter M20_dimer PF07687.14 EOO04199.1 - 2.6e-07 30.5 0.0 4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EOO04199.1 - 3e-05 23.8 0.0 3.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Arf PF00025.21 EOO04200.1 - 3.3e-65 218.8 0.5 3.9e-65 218.6 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EOO04200.1 - 1.7e-14 54.1 0.0 2.4e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EOO04200.1 - 3.7e-13 49.4 0.1 4.3e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EOO04200.1 - 8.7e-13 48.1 1.9 6.4e-09 35.4 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EOO04200.1 - 1.1e-11 44.5 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EOO04200.1 - 1.2e-11 44.4 0.1 1.5e-11 44.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EOO04200.1 - 0.00033 20.7 0.0 0.00044 20.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EOO04200.1 - 0.058 12.7 0.2 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase SpoOE-like PF09388.10 EOO04200.1 - 0.063 13.2 0.8 0.16 11.9 0.8 1.6 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein MobB PF03205.14 EOO04200.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_cyclohydro2 PF00925.20 EOO04201.1 - 1.7e-60 203.3 0.0 2.5e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II SPX PF03105.19 EOO04201.1 - 2.9 7.7 5.8 3.6 7.4 5.8 1.2 1 0 0 1 1 1 0 SPX domain NmrA PF05368.13 EOO04202.1 - 1.1e-29 103.7 0.0 1.3e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO04202.1 - 1.3e-19 70.9 0.0 1.7e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EOO04202.1 - 0.035 13.1 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RPA43_OB PF17875.1 EOO04203.1 - 2.2e-34 118.8 0.0 2.2e-34 118.8 0.0 3.8 3 1 0 4 4 4 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EOO04203.1 - 2.1e-06 28.0 0.0 4.1e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 His_biosynth PF00977.21 EOO04204.1 - 1e-48 165.8 0.2 5.4e-48 163.5 0.2 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EOO04204.1 - 5.3e-20 72.0 0.0 8.3e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EOO04204.1 - 5.1e-11 42.8 0.0 5.3e-10 39.5 0.0 2.1 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EOO04204.1 - 8.8e-07 28.7 0.0 2.2e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 EOO04204.1 - 0.079 12.7 0.1 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 Dus PF01207.17 EOO04204.1 - 0.23 10.5 0.0 0.64 9.1 0.0 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) AA_permease_2 PF13520.6 EOO04205.1 - 1e-23 83.9 24.8 1.2e-23 83.7 24.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EOO04205.1 - 4.5e-07 28.8 16.7 5.1e-07 28.6 16.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3784 PF12650.7 EOO04205.1 - 0.82 9.9 5.7 0.29 11.4 0.5 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3784) Sugar_tr PF00083.24 EOO04206.1 - 1.6e-83 281.1 25.2 2.5e-82 277.1 25.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO04206.1 - 5.5e-26 91.3 39.7 5.8e-26 91.3 30.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.26 EOO04207.1 - 7.1e-12 45.4 0.0 1.4e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EOO04207.1 - 4.3e-09 36.2 0.1 1.7e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EOO04207.1 - 2.8e-08 34.9 0.0 5.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EOO04207.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase PMI_typeI PF01238.21 EOO04208.1 - 6.4e-134 446.8 0.0 7.5e-134 446.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I RCS1 PF07326.11 EOO04208.1 - 0.018 15.0 0.2 0.028 14.4 0.2 1.2 1 0 0 1 1 1 0 Regulator of chromosome segregation 1 Cupin_2 PF07883.11 EOO04208.1 - 0.11 12.2 0.1 5.7 6.7 0.1 2.5 2 1 0 2 2 2 0 Cupin domain GSIII_N PF12437.8 EOO04208.1 - 0.14 11.8 0.2 0.27 10.9 0.2 1.4 1 0 0 1 1 1 0 Glutamine synthetase type III N terminal Pkinase PF00069.25 EOO04209.1 - 7.1e-63 212.4 0.0 9.3e-63 212.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO04209.1 - 1.4e-30 106.4 0.0 2.3e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EOO04209.1 - 0.013 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 EOO04209.1 - 0.05 12.9 0.1 0.1 11.9 0.1 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 EOO04209.1 - 0.062 13.2 0.0 0.24 11.3 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family CFEM PF05730.11 EOO04210.1 - 3.7e-12 46.1 13.9 5.3e-12 45.7 13.9 1.2 1 0 0 1 1 1 1 CFEM domain Metallothio_Euk PF12749.7 EOO04210.1 - 0.49 10.6 8.9 0.95 9.7 8.9 1.7 1 1 0 1 1 1 0 Eukaryotic metallothionein Sporozoite_P67 PF05642.11 EOO04210.1 - 0.64 8.0 6.5 0.63 8.1 6.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NmrA PF05368.13 EOO04211.1 - 6.7e-32 110.9 0.2 8.5e-32 110.6 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EOO04211.1 - 1.1e-11 44.9 0.1 3.8e-11 43.2 0.1 1.9 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EOO04211.1 - 0.0015 17.6 0.1 0.0023 17.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EOO04211.1 - 0.0018 17.8 0.1 0.071 12.6 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EOO04211.1 - 0.004 17.3 0.0 0.042 14.0 0.0 2.2 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 EOO04211.1 - 0.037 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 EOO04211.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LMWPc PF01451.21 EOO04212.1 - 2.1e-39 135.1 0.0 2.4e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Glyco_hydro_127 PF07944.12 EOO04213.1 - 2.3e-20 72.6 0.1 5.3e-20 71.4 0.0 1.5 2 0 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 Yippee-Mis18 PF03226.14 EOO04214.1 - 2.1e-17 63.3 0.0 3.5e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EOO04214.1 - 0.0042 17.3 0.0 0.091 13.0 0.0 2.1 2 0 0 2 2 2 1 C-terminal domain of RIG-I MFS_1 PF07690.16 EOO04215.1 - 1.5e-08 34.0 26.9 3.4e-08 32.8 26.9 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily ICL PF00463.21 EOO04216.1 - 5.3e-123 411.3 0.3 6.5e-123 411.0 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EOO04216.1 - 4.5e-06 26.3 0.0 7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Ank_2 PF12796.7 EOO04217.1 - 2.8e-13 50.3 0.0 0.0001 22.8 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EOO04217.1 - 3.6e-10 40.2 0.1 0.0022 18.5 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EOO04217.1 - 1.2e-09 38.2 0.0 0.002 18.5 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EOO04217.1 - 5.7e-09 36.1 0.6 0.00029 21.1 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EOO04217.1 - 4.3e-08 32.8 0.0 0.1 13.2 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 EOO04217.1 - 1.9e-07 30.9 0.2 2.2e-06 27.5 0.2 2.4 1 1 0 1 1 1 1 KilA-N domain End3 PF12761.7 EOO04217.1 - 0.031 14.5 3.4 0.042 14.0 0.5 2.4 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Tex_N PF09371.10 EOO04217.1 - 0.033 13.9 1.2 0.084 12.5 0.8 1.9 2 0 0 2 2 2 0 Tex-like protein N-terminal domain TAF6_C PF07571.13 EOO04217.1 - 0.083 13.2 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain AAA_13 PF13166.6 EOO04217.1 - 0.3 9.7 3.3 0.5 8.9 3.3 1.3 1 0 0 1 1 1 0 AAA domain HlyD_D4 PF16572.5 EOO04217.1 - 0.37 10.7 4.5 3.1 7.7 0.1 3.3 3 0 0 3 3 3 0 Long alpha hairpin domain of cation efflux system protein, CusB SnAC PF14619.6 EOO04217.1 - 4.2 8.1 6.4 0.87 10.2 1.0 2.6 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex Pro_isomerase PF00160.21 EOO04218.1 - 3.4e-23 82.7 0.0 4.3e-22 79.1 0.0 2.1 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EOO04218.1 - 1.6e-14 53.4 0.0 3.2e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Thioredoxin_7 PF13899.6 EOO04219.1 - 5.3e-18 65.0 0.1 1.8e-17 63.3 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin-like UBA_4 PF14555.6 EOO04219.1 - 4.1e-13 48.9 0.2 1.2e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.20 EOO04219.1 - 1.3e-08 34.9 0.0 2.7e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.15 EOO04219.1 - 0.0024 17.8 0.1 0.0041 17.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 GET2 PF08690.10 EOO04219.1 - 0.0083 15.8 1.4 0.017 14.8 1.4 1.5 1 0 0 1 1 1 1 GET complex subunit GET2 Thioredoxin_2 PF13098.6 EOO04219.1 - 0.055 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Prothymosin PF03247.14 EOO04219.1 - 6.6 7.2 10.3 0.34 11.4 3.7 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family Pedibin PF08182.11 EOO04220.1 - 0.39 10.6 4.2 0.42 10.5 0.8 2.3 2 0 0 2 2 2 0 Pedibin/Hym-346 family Iso_dh PF00180.20 EOO04221.1 - 1.1e-80 271.4 0.0 1.3e-80 271.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DEAD PF00270.29 EOO04222.1 - 8.6e-45 152.6 0.0 7e-42 143.2 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EOO04222.1 - 2.1e-20 73.1 0.0 1.8e-18 66.9 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EOO04222.1 - 1.9e-07 31.2 0.0 3.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EOO04222.1 - 0.043 13.5 0.1 0.096 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EOO04222.1 - 0.09 12.5 0.0 13 5.5 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 EOO04222.1 - 0.13 12.5 0.9 1.4 9.2 1.0 2.5 2 1 0 2 2 2 0 AAA domain Tyrosinase PF00264.20 EOO04223.1 - 2.1e-49 168.8 1.0 2.9e-49 168.4 1.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase XPG_I_2 PF12813.7 EOO04223.1 - 0.16 11.4 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 XPG domain containing WBS_methylT PF12589.8 EOO04224.1 - 8.5e-14 52.1 4.4 1.7e-13 51.1 4.4 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EOO04224.1 - 3e-12 47.0 0.0 5.4e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EOO04224.1 - 1.4e-10 41.7 0.0 4.3e-10 40.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EOO04224.1 - 3.1e-05 24.6 0.0 8.4e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EOO04224.1 - 0.00042 20.2 0.0 0.00065 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EOO04224.1 - 0.0016 18.2 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EOO04224.1 - 0.024 14.5 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EOO04224.1 - 0.064 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EOO04224.1 - 0.066 12.5 0.0 0.36 10.1 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Abhydrolase_6 PF12697.7 EOO04225.1 - 3.5e-06 27.8 1.0 4.7e-06 27.4 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sugar_tr PF00083.24 EOO04226.1 - 4e-12 45.8 5.7 4e-12 45.7 5.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO04228.1 - 1e-07 31.2 1.5 1.2e-07 31.0 1.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DPBB_1 PF03330.18 EOO04229.1 - 9.9e-08 32.2 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase adh_short PF00106.25 EOO04230.1 - 2.5e-15 56.4 0.0 3.8e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO04230.1 - 2.8e-08 33.6 0.0 3.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EOO04230.1 - 0.00039 19.9 0.0 0.00043 19.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 EOO04231.1 - 6.6e-25 87.6 0.6 1e-24 87.0 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EOO04231.1 - 4.2e-05 24.6 0.1 7.1e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EOO04231.1 - 0.00053 19.5 1.1 0.00079 19.0 1.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EOO04231.1 - 0.02 14.3 1.4 0.032 13.7 1.4 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.6 EOO04231.1 - 0.061 13.2 2.1 0.77 9.6 2.1 2.2 2 0 0 2 2 2 0 NAD(P)H-binding AlaDh_PNT_C PF01262.21 EOO04231.1 - 0.11 11.8 5.6 0.24 10.7 5.6 1.7 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FTCD_C PF04961.12 EOO04231.1 - 0.55 10.0 5.4 0.17 11.6 2.6 1.6 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase Alpha-amylase PF00128.24 EOO04232.1 - 2.1e-17 63.7 0.0 1.2e-08 34.9 0.0 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 EOO04232.1 - 0.063 13.8 0.0 0.18 12.3 0.0 1.7 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain Pkinase PF00069.25 EOO04234.1 - 3.2e-69 233.2 0.0 5.5e-69 232.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO04234.1 - 1.2e-50 172.2 0.0 2.1e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EOO04234.1 - 0.00011 21.2 0.5 0.0016 17.3 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase TFIIA PF03153.13 EOO04234.1 - 6.2 6.7 32.3 10 6.0 32.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ecm29 PF13001.7 EOO04235.1 - 4.7e-156 520.3 0.0 2.4e-152 508.1 0.0 3.1 3 0 0 3 3 3 2 Proteasome stabiliser HEAT PF02985.22 EOO04235.1 - 0.00013 22.0 2.1 1.7 9.1 0.0 6.0 5 0 0 5 5 5 2 HEAT repeat DUF4042 PF13251.6 EOO04235.1 - 0.0015 18.3 0.0 0.16 11.7 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4042) HEAT_EZ PF13513.6 EOO04235.1 - 0.0066 16.9 4.5 5.5 7.6 0.1 6.8 7 1 0 7 7 7 1 HEAT-like repeat MMS19_C PF12460.8 EOO04235.1 - 0.18 10.9 2.9 3.3 6.7 0.0 3.9 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal Abhydrolase_3 PF07859.13 EOO04236.1 - 7.5e-42 143.6 0.0 1.7e-41 142.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EOO04236.1 - 1.2e-05 24.4 0.0 4.5e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase LIP PF03583.14 EOO04236.1 - 0.0065 15.8 0.0 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase COesterase PF00135.28 EOO04236.1 - 0.019 13.9 0.2 1.8 7.4 0.1 2.1 2 0 0 2 2 2 0 Carboxylesterase family Lipase_GDSL_2 PF13472.6 EOO04237.1 - 1.4e-08 35.4 0.1 1.4e-06 28.8 0.0 2.5 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EOO04237.1 - 0.00025 21.1 0.0 0.00067 19.7 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RRM_1 PF00076.22 EOO04238.1 - 1.6e-48 162.3 0.0 1.3e-16 60.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EOO04238.1 - 1.1e-05 25.3 0.2 0.0022 18.0 0.1 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EOO04238.1 - 0.00027 20.9 0.0 0.0017 18.4 0.0 2.2 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 EOO04238.1 - 0.00061 19.9 0.2 0.051 13.7 0.0 2.9 3 1 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 EOO04238.1 - 0.0014 18.4 0.0 0.049 13.5 0.0 2.6 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 EOO04238.1 - 0.05 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5339 PF17274.2 EOO04239.1 - 0.61 11.0 7.2 0.12 13.2 1.7 2.7 4 0 0 4 4 4 0 Family of unknown function (DUF5339) DUF4407 PF14362.6 EOO04239.1 - 1.2 8.4 3.3 1.9 7.8 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 EOO04239.1 - 1.7 8.9 7.9 0.18 12.1 2.6 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF5320 PF17253.2 EOO04239.1 - 2.1 9.5 0.0 2.1 9.5 0.0 2.9 4 0 0 4 4 4 0 Family of unknown function (DUF5320) Glyoxalase PF00903.25 EOO04240.1 - 3.1e-11 43.6 0.0 4.8e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EOO04240.1 - 4e-09 36.7 0.0 4.9e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EOO04240.1 - 1.3e-05 25.9 0.0 1.9e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EOO04240.1 - 0.0067 16.6 0.0 0.11 12.6 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain DUF5404 PF17397.2 EOO04240.1 - 0.029 14.5 0.0 0.04 14.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5404) DUF2157 PF09925.9 EOO04242.1 - 0.21 11.4 2.4 0.67 9.7 2.4 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) Dabb PF07876.12 EOO04243.1 - 6.7e-16 58.7 0.0 8e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF3292 PF11696.8 EOO04244.1 - 2.6e-287 954.6 0.0 3.2e-287 954.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) MFS_1 PF07690.16 EOO04245.1 - 1.8e-42 145.5 58.5 2.7e-42 144.9 52.7 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EOO04245.1 - 4.4e-12 45.2 19.3 5.8e-12 44.8 19.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EOO04245.1 - 1.5e-06 27.3 12.8 1.5e-06 27.3 12.8 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter VCBS PF13517.6 EOO04246.1 - 6.3e-34 116.4 46.7 2.2e-13 50.6 1.3 8.4 4 2 4 8 8 8 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 EOO04246.1 - 4.1e-12 46.8 0.2 9.2e-12 45.7 0.2 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.8 EOO04246.1 - 8.9e-09 35.0 5.1 0.13 11.6 0.0 6.4 6 1 1 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL PF00657.22 EOO04246.1 - 3.6e-06 27.1 0.0 6.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FG-GAP PF01839.23 EOO04246.1 - 0.02 15.0 0.2 0.02 15.0 0.2 8.4 9 0 0 9 9 9 0 FG-GAP repeat Dockerin_1 PF00404.18 EOO04246.1 - 0.13 12.5 10.4 2.1 8.6 0.0 5.5 6 0 0 6 6 6 0 Dockerin type I domain FAD_binding_3 PF01494.19 EOO04247.1 - 5.5e-12 45.6 0.1 7e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain ApoLp-III PF07464.11 EOO04249.1 - 0.00038 20.6 0.4 0.00047 20.3 0.4 1.2 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.7 EOO04249.1 - 0.0065 17.0 3.5 8.8 6.9 0.0 3.0 1 1 1 2 2 2 2 YtxH-like protein ATG_C PF09333.11 EOO04249.1 - 0.0087 16.4 0.2 0.068 13.5 0.2 2.7 1 1 0 1 1 1 1 Autophagy-related protein C terminal domain Phasin PF05597.11 EOO04249.1 - 0.035 14.1 0.9 1.2 9.2 0.4 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF883 PF05957.13 EOO04249.1 - 0.041 14.5 0.1 8.7 7.0 0.1 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF16 PF01519.16 EOO04249.1 - 0.054 14.0 0.3 0.28 11.7 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 GvpL_GvpF PF06386.11 EOO04249.1 - 0.083 12.8 0.0 0.098 12.6 0.0 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Chlorosome_CsmC PF11098.8 EOO04249.1 - 0.17 11.9 6.8 0.34 10.9 4.4 2.2 1 1 1 2 2 2 0 Chlorosome envelope protein C adh_short PF00106.25 EOO04252.1 - 2.3e-38 131.6 1.5 3.2e-38 131.1 1.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO04252.1 - 1.4e-31 109.8 0.2 2e-31 109.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO04252.1 - 2.7e-09 37.2 4.1 2.4e-08 34.1 4.1 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EOO04252.1 - 0.0053 16.2 0.2 0.0086 15.6 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HDPD PF02924.14 EOO04252.1 - 0.36 11.0 2.3 0.52 10.4 0.3 2.0 2 0 0 2 2 2 0 Bacteriophage lambda head decoration protein D HBB PF06777.11 EOO04253.1 - 5.3e-50 169.7 1.9 6.4e-45 153.2 0.4 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 EOO04253.1 - 4.9e-44 150.5 0.1 2.1e-43 148.5 0.0 2.1 3 0 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.15 EOO04253.1 - 7.9e-19 67.9 1.1 7.9e-19 67.9 1.1 2.0 2 0 0 2 2 2 1 DEAD_2 ORC5_C PF14630.6 EOO04254.1 - 4e-88 295.6 0.0 5.6e-88 295.1 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EOO04254.1 - 4e-20 72.9 0.1 8.5e-20 71.8 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EOO04254.1 - 0.0018 18.5 0.0 0.0079 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 EOO04254.1 - 0.0023 17.4 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein ATPase_2 PF01637.18 EOO04254.1 - 0.008 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 EOO04254.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EOO04254.1 - 0.16 11.5 0.0 0.39 10.2 0.0 1.6 1 1 1 2 2 2 0 P-loop containing dynein motor region WD40 PF00400.32 EOO04255.1 - 6.8e-28 96.3 9.3 1.8e-08 34.9 0.0 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO04255.1 - 3.1e-05 24.2 0.2 1.1 9.5 0.1 4.5 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EOO04255.1 - 0.054 12.4 0.6 0.39 9.6 0.3 2.2 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein T-box_assoc PF16176.5 EOO04255.1 - 0.06 13.4 0.6 0.11 12.5 0.6 1.4 1 0 0 1 1 1 0 T-box transcription factor-associated VCBS PF13517.6 EOO04255.1 - 0.12 13.0 0.7 4.5 8.0 0.0 3.1 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Coatomer_WDAD PF04053.14 EOO04255.1 - 0.16 10.9 1.0 0.39 9.7 0.5 1.7 2 0 0 2 2 2 0 Coatomer WD associated region PUF PF00806.19 EOO04256.1 - 2e-37 124.8 0.6 4.4e-06 26.1 0.0 9.2 10 0 0 10 10 10 7 Pumilio-family RNA binding repeat RraB PF06877.11 EOO04256.1 - 0.11 13.2 0.0 0.45 11.3 0.0 1.9 2 0 0 2 2 2 0 Regulator of ribonuclease activity B WDCP PF15390.6 EOO04256.1 - 0.13 10.6 1.4 0.18 10.2 1.4 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Cpn60_TCP1 PF00118.24 EOO04257.1 - 7.1e-86 288.8 10.3 1.8e-85 287.5 10.3 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1542 PF07564.11 EOO04257.1 - 4.6 7.4 5.9 8 6.7 0.8 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) DUF5572 PF17733.1 EOO04258.1 - 1.7e-13 50.2 1.3 1.7e-13 50.2 1.3 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5572) Nramp PF01566.18 EOO04259.1 - 1.8e-72 244.3 14.7 1.8e-72 244.3 14.7 1.6 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Sigma_reg_N PF13800.6 EOO04259.1 - 6.9 7.0 7.1 22 5.4 0.0 3.6 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Pkinase PF00069.25 EOO04260.1 - 7.5e-12 45.2 0.0 1.1e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EOO04260.1 - 9.5e-05 21.8 0.0 0.0014 18.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Alpha-L-AF_C PF06964.12 EOO04261.1 - 4.3e-29 101.8 0.0 6.9e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Sds3 PF08598.11 EOO04263.1 - 7.8e-23 81.6 2.6 1.3e-22 80.9 2.6 1.4 1 0 0 1 1 1 1 Sds3-like Alpha-amylase_C PF02806.18 EOO04264.1 - 5.6e-26 90.8 0.0 1.8e-25 89.2 0.0 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 EOO04264.1 - 6.7e-15 55.5 0.1 1.5e-11 44.4 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 EOO04264.1 - 1.8e-09 37.8 0.0 2.9e-08 34.0 0.0 2.5 1 1 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Cellulase PF00150.18 EOO04264.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) hDGE_amylase PF14701.6 EOO04264.1 - 0.15 11.2 0.1 0.24 10.5 0.1 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Mob1_phocein PF03637.17 EOO04265.1 - 3.9e-70 235.3 0.0 5.8e-70 234.7 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family DSPc PF00782.20 EOO04266.1 - 0.00022 21.0 0.0 0.043 13.6 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Aldo_ket_red PF00248.21 EOO04267.1 - 2.2e-37 128.8 0.1 6.2e-36 124.1 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family LBP_C PF17386.2 EOO04268.1 - 0.16 11.9 0.9 7.4 6.6 0.0 2.8 3 0 0 3 3 3 0 Lacto-N-biose phosphorylase C-terminal domain Med3 PF11593.8 EOO04269.1 - 0.00074 18.8 6.5 0.00092 18.5 6.5 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Pox_Ag35 PF03286.14 EOO04269.1 - 0.053 13.3 4.2 0.076 12.8 4.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GET2 PF08690.10 EOO04269.1 - 0.54 9.9 3.3 0.78 9.4 3.3 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 OSCP PF00213.18 EOO04270.1 - 4.4e-47 160.4 0.2 5.2e-47 160.2 0.2 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Glyco_hydro_63 PF03200.16 EOO04271.1 - 1.2e-07 30.9 4.0 4e-05 22.6 0.1 3.5 3 1 0 3 3 3 2 Glycosyl hydrolase family 63 C-terminal domain Hep_59 PF07052.11 EOO04271.1 - 0.037 14.8 1.2 0.09 13.5 1.2 1.6 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 SpoVIF PF14069.6 EOO04272.1 - 0.00065 19.4 0.0 0.13 12.1 0.0 2.7 3 0 0 3 3 3 2 Stage VI sporulation protein F INO80_Ies4 PF08193.11 EOO04272.1 - 0.00074 19.6 6.5 0.00091 19.3 6.5 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 DUF382 PF04037.13 EOO04273.1 - 2.2e-59 199.1 0.8 2.2e-59 199.1 0.8 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 EOO04273.1 - 2e-20 72.4 3.0 4.6e-20 71.2 3.0 1.7 1 0 0 1 1 1 1 PSP TIP49 PF06068.13 EOO04275.1 - 1.2e-154 514.7 2.1 1.5e-154 514.4 2.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EOO04275.1 - 2.4e-21 75.6 0.1 8.5e-21 73.9 0.1 2.1 2 0 0 2 2 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 EOO04275.1 - 6e-09 35.8 0.6 6.7e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 EOO04275.1 - 1.1e-07 32.4 1.5 0.00012 22.5 0.0 3.2 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 EOO04275.1 - 4e-06 26.3 0.9 8.4e-06 25.3 0.9 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EOO04275.1 - 1.5e-05 25.4 0.1 4.7e-05 23.8 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EOO04275.1 - 0.00065 19.1 0.9 0.013 14.8 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EOO04275.1 - 0.0078 16.5 0.0 0.64 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EOO04275.1 - 0.0088 15.8 0.1 3.4 7.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 EOO04275.1 - 0.012 15.9 2.7 0.95 9.8 2.7 2.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EOO04275.1 - 0.021 14.9 0.1 2.9 7.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EOO04275.1 - 0.032 14.0 0.9 0.2 11.4 0.9 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EOO04275.1 - 0.035 13.7 0.1 0.066 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EOO04275.1 - 0.089 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 EOO04275.1 - 0.11 12.7 0.0 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EOO04275.1 - 0.12 11.9 0.2 0.5 9.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region MRP-S33 PF08293.11 EOO04276.1 - 2e-33 114.5 0.0 2.4e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 UFD1 PF03152.14 EOO04277.1 - 1.9e-59 200.0 0.0 2.6e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 EOO04277.1 - 0.063 13.1 0.1 0.16 11.8 0.1 1.7 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 LXG PF04740.12 EOO04278.1 - 0.077 12.7 0.2 2.1 8.0 0.2 2.1 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF4726 PF15855.5 EOO04278.1 - 0.11 12.7 0.6 20 5.5 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4726) DUF31 PF01732.16 EOO04278.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF31) Histone PF00125.24 EOO04279.1 - 1.6e-51 174.1 2.5 1.8e-51 173.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EOO04279.1 - 8.4e-06 26.1 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EOO04279.1 - 3.4e-05 24.5 1.0 3.9e-05 24.3 1.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EOO04279.1 - 3.6e-05 23.8 0.4 6.4e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EOO04279.1 - 0.0035 17.6 0.3 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EOO04279.1 - 0.028 14.5 0.2 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EOO04279.1 - 0.057 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DAO PF01266.24 EOO04280.1 - 1e-52 179.9 0.0 1.5e-52 179.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EOO04280.1 - 5.8e-44 149.0 0.1 1e-43 148.2 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EOO04280.1 - 2.4e-08 33.5 0.1 6.1e-08 32.1 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EOO04280.1 - 9.4e-05 21.8 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EOO04280.1 - 0.00023 20.7 0.0 0.002 17.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EOO04280.1 - 0.00099 18.4 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EOO04280.1 - 0.0024 18.1 0.2 0.011 16.0 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 EOO04280.1 - 0.011 15.6 0.2 0.026 14.4 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 EOO04280.1 - 0.014 14.7 0.8 0.035 13.3 0.2 1.8 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 EOO04280.1 - 0.019 13.7 0.3 0.03 13.0 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 EOO04280.1 - 0.029 13.5 0.1 0.14 11.2 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EOO04280.1 - 0.03 13.6 0.0 0.21 10.8 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 EOO04280.1 - 0.044 14.4 0.3 0.11 13.1 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RPN6_N PF18055.1 EOO04282.1 - 1.7e-47 160.6 0.4 1.7e-47 160.6 0.4 2.7 3 1 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EOO04282.1 - 2.6e-21 76.1 0.3 1.2e-20 74.0 0.2 2.2 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 EOO04282.1 - 9.6e-11 41.2 1.2 2.2e-10 40.1 1.2 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 EOO04282.1 - 5.7e-05 22.8 0.5 9.9e-05 22.0 0.5 1.4 1 0 0 1 1 1 1 DDRGK domain TPR_MalT PF17874.1 EOO04282.1 - 0.00036 20.0 2.1 0.00036 20.0 2.1 2.5 2 1 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 EOO04282.1 - 0.0014 18.5 6.2 0.63 10.2 0.3 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EOO04282.1 - 0.012 15.7 5.4 9.4 6.6 0.0 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EOO04282.1 - 0.018 15.4 22.0 0.039 14.2 3.1 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat HTH_Crp_2 PF13545.6 EOO04282.1 - 0.044 13.8 0.1 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DprA_WH PF17782.1 EOO04282.1 - 0.086 13.0 0.0 0.32 11.2 0.0 2.0 2 0 0 2 2 1 0 DprA winged helix domain TPR_4 PF07721.14 EOO04282.1 - 0.096 13.4 0.3 0.58 10.9 0.1 2.5 2 0 0 2 2 1 0 Tetratricopeptide repeat DUF4398 PF14346.6 EOO04282.1 - 0.31 11.7 9.8 0.087 13.5 2.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) TPR_1 PF00515.28 EOO04282.1 - 0.31 10.9 7.2 20 5.2 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EOO04282.1 - 0.36 11.2 9.2 21 5.7 0.0 5.6 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 EOO04282.1 - 7.9 6.1 16.3 4.6 6.9 2.6 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat-like domain F-box-like PF12937.7 EOO04283.1 - 0.002 18.0 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_9 PF14580.6 EOO04283.1 - 0.11 12.0 0.0 5.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeat LRR_8 PF13855.6 EOO04283.1 - 0.5 10.2 3.7 1.1 9.1 0.3 3.1 3 0 0 3 3 3 0 Leucine rich repeat Phe_hydrox_dim PF07976.12 EOO04284.1 - 2e-40 138.5 0.0 3.5e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_3 PF01494.19 EOO04284.1 - 2.1e-25 89.8 0.2 4.1e-25 88.8 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain Methyltr_RsmB-F PF01189.17 EOO04285.1 - 3.5e-77 258.6 0.0 5.9e-77 257.8 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EOO04285.1 - 1.2e-07 32.1 0.0 4e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Toprim_Crpt PF13342.6 EOO04285.1 - 0.0096 15.9 0.1 0.027 14.4 0.1 1.7 1 0 0 1 1 1 1 C-terminal repeat of topoisomerase DUF2431 PF10354.9 EOO04285.1 - 0.028 14.7 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Methyltransf_25 PF13649.6 EOO04285.1 - 0.065 13.9 0.0 0.21 12.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DUF4717 PF15838.5 EOO04285.1 - 0.11 12.5 3.3 1 9.4 4.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4717) ATP-synt_ab PF00006.25 EOO04286.1 - 8.9e-62 208.5 0.0 1.5e-61 207.8 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EOO04286.1 - 5.6e-24 84.4 0.5 2.4e-23 82.4 0.3 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 EOO04286.1 - 0.013 15.4 0.2 0.028 14.3 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase T3SS_ATPase_C PF18269.1 EOO04286.1 - 0.016 15.1 1.0 0.09 12.7 1.0 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain ATPase_2 PF01637.18 EOO04286.1 - 0.017 15.1 0.0 0.05 13.5 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EOO04286.1 - 0.017 14.3 0.6 0.082 12.1 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 EOO04286.1 - 0.02 15.3 0.1 0.77 10.2 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EOO04286.1 - 0.039 13.3 0.1 0.07 12.5 0.1 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 EOO04286.1 - 0.049 13.5 0.1 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 EOO04286.1 - 0.053 13.9 0.6 0.49 10.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EOO04286.1 - 0.079 13.3 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EOO04286.1 - 0.15 12.5 0.1 0.52 10.7 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain Blt1 PF12754.7 EOO04287.1 - 2.9e-43 147.8 2.3 4e-43 147.3 2.3 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 EOO04287.1 - 4.9e-18 64.5 0.3 8.7e-18 63.7 0.3 1.4 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 EOO04287.1 - 0.00048 19.8 0.3 0.00078 19.2 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family XRCC4 PF06632.12 EOO04288.1 - 1.3e-08 34.1 15.4 8.4e-08 31.4 15.4 1.9 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 CENP-F_leu_zip PF10473.9 EOO04288.1 - 0.011 15.8 1.0 0.011 15.8 1.0 1.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.16 EOO04288.1 - 0.012 15.8 3.2 0.022 15.0 3.2 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein PEP-utilisers_N PF05524.13 EOO04288.1 - 0.012 15.7 3.6 0.11 12.6 2.0 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal HrpJ PF07201.11 EOO04288.1 - 0.11 12.8 5.8 0.24 11.7 5.8 1.5 1 0 0 1 1 1 0 HrpJ-like domain WXG100 PF06013.12 EOO04288.1 - 0.41 10.9 3.3 1.1 9.5 3.3 1.7 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Pectate_lyase_3 PF12708.7 EOO04289.1 - 1.6e-63 214.4 22.0 8.5e-55 185.9 4.1 3.8 3 1 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EOO04289.1 - 0.0016 18.1 7.8 0.27 10.9 0.4 3.6 4 0 0 4 4 4 2 N terminal extension of bacteriophage endosialidase Adeno_E1B_55K PF01696.17 EOO04289.1 - 0.01 14.5 0.4 0.017 13.8 0.4 1.2 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen MIP PF00230.20 EOO04291.1 - 4.3e-27 95.3 12.9 5.5e-27 94.9 12.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein Sugar_tr PF00083.24 EOO04292.1 - 2e-95 320.3 15.9 2.8e-95 319.8 15.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO04292.1 - 2.5e-27 95.7 21.7 1.5e-19 70.2 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 EOO04292.1 - 0.0066 15.3 1.7 0.0066 15.3 1.7 2.0 1 1 1 2 2 2 1 LacY proton/sugar symporter DUF2838 PF10998.8 EOO04292.1 - 0.052 13.8 3.6 1.4 9.2 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2838) Transket_pyr PF02779.24 EOO04293.1 - 8.1e-65 217.8 0.0 1.5e-64 217.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 EOO04293.1 - 5.9e-58 194.9 0.1 9.6e-58 194.2 0.1 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 EOO04293.1 - 1.1e-57 195.3 0.0 1.6e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 EOO04293.1 - 2.1e-19 68.8 0.9 4.7e-19 67.7 0.9 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus PP2C PF00481.21 EOO04294.1 - 2.8e-45 155.0 0.0 4.3e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EOO04294.1 - 2.2e-05 24.5 0.0 0.035 14.0 0.0 3.0 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EOO04294.1 - 0.00041 20.0 0.1 0.0008 19.1 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Thioredoxin_15 PF18403.1 EOO04294.1 - 0.0088 16.0 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_hydro_72 PF03198.14 EOO04295.1 - 3.2e-101 338.7 0.2 9.5e-101 337.2 0.2 1.6 2 0 0 2 2 2 1 Glucanosyltransferase Peptidase_C48 PF02902.19 EOO04296.1 - 5.5e-18 65.6 0.0 1.3e-17 64.3 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain COX4 PF02936.14 EOO04297.1 - 5.4e-49 165.8 0.1 6.4e-49 165.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Ni_hydr_CYTB PF01292.20 EOO04297.1 - 0.033 13.8 0.1 0.042 13.4 0.1 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF1104 PF06518.11 EOO04297.1 - 0.13 12.7 0.1 0.22 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) DUF569 PF04601.13 EOO04299.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF569) WD40 PF00400.32 EOO04300.1 - 9.6e-11 42.1 6.2 0.013 16.4 0.0 6.9 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO04300.1 - 1.1e-07 32.1 0.6 0.024 14.9 0.1 5.6 2 2 5 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EOO04300.1 - 0.0042 17.0 0.0 1.9 8.3 0.0 3.4 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Sof1 PF04158.14 EOO04302.1 - 3e-30 104.3 20.8 4.4e-30 103.8 20.8 1.2 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EOO04302.1 - 6.2e-16 58.5 0.0 1.1e-06 29.3 0.1 2.4 1 1 1 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO04302.1 - 7.7e-05 22.9 0.0 0.039 14.3 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EOO04302.1 - 0.00049 20.1 0.0 0.76 9.8 0.0 2.5 1 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 EOO04302.1 - 0.0012 17.9 0.0 0.04 12.9 0.0 2.1 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein tRNA_m1G_MT PF01746.21 EOO04302.1 - 0.016 14.9 0.5 0.033 13.9 0.4 1.6 2 0 0 2 2 2 0 tRNA (Guanine-1)-methyltransferase ACBP PF00887.19 EOO04303.1 - 7.1e-25 87.0 0.0 8.1e-25 86.9 0.0 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 EOO04303.1 - 0.11 13.0 0.1 0.85 10.0 0.0 2.0 1 1 0 2 2 2 0 FERM central domain PRP3 PF08572.10 EOO04306.1 - 5.6e-64 215.9 7.7 1.2e-63 214.9 7.7 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EOO04306.1 - 1.2e-50 171.4 2.3 1.2e-50 171.4 2.3 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) GET2 PF08690.10 EOO04306.1 - 0.53 9.9 9.4 0.043 13.5 4.7 1.6 2 0 0 2 2 2 0 GET complex subunit GET2 Myb_DNA-bind_4 PF13837.6 EOO04307.1 - 0.19 12.1 0.0 0.27 11.6 0.0 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain LSM PF01423.22 EOO04308.1 - 1.8e-15 56.4 0.0 2.7e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 LSM domain DNA_pol3_delta2 PF13177.6 EOO04309.1 - 6e-11 42.4 0.0 1.2e-10 41.5 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EOO04309.1 - 2.1e-06 28.2 0.0 4.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EOO04309.1 - 7.1e-06 26.3 0.2 8.2e-05 22.9 0.1 2.3 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EOO04309.1 - 0.00036 20.9 0.5 0.0038 17.6 0.4 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EOO04309.1 - 0.0004 20.2 0.2 0.0029 17.4 0.2 2.2 2 1 0 2 2 2 1 AAA domain Rep_fac_C PF08542.11 EOO04309.1 - 0.00049 20.5 0.0 0.0015 18.9 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 EOO04309.1 - 0.0097 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain ABC_tran PF00005.27 EOO04309.1 - 0.028 14.9 0.0 0.059 13.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.14 EOO04309.1 - 0.034 12.9 0.1 0.16 10.7 0.0 1.9 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer DNA_pol3_delta PF06144.13 EOO04309.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Neugrin PF06413.11 EOO04310.1 - 5.4e-13 49.5 1.3 6.2e-13 49.3 0.6 1.5 1 1 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 EOO04310.1 - 4.7e-07 30.1 2.9 1.4e-06 28.6 2.9 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Skp1 PF01466.19 EOO04310.1 - 0.0061 16.6 0.5 0.012 15.8 0.5 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain UPF0061 PF02696.14 EOO04311.1 - 2.8e-128 428.7 0.0 4.2e-128 428.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family BSD PF03909.17 EOO04312.1 - 2.2e-28 98.0 5.6 7e-15 54.8 0.1 3.0 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 EOO04312.1 - 1.6e-27 95.6 0.0 6e-27 93.8 0.0 2.1 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF5499 PF17603.2 EOO04312.1 - 0.087 13.4 0.1 0.25 12.0 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5499) DUF4214 PF13946.6 EOO04312.1 - 0.1 12.7 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) Rick_17kDa_Anti PF05433.15 EOO04313.1 - 0.15 12.0 16.6 0.47 10.4 3.9 2.3 1 1 2 3 3 3 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EOO04313.1 - 0.16 12.0 12.7 2.8 8.0 13.1 2.2 1 1 0 1 1 1 0 Glycine zipper DUF2530 PF10745.9 EOO04313.1 - 0.34 11.2 3.0 14 6.0 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2530) DUF3824 PF12868.7 EOO04313.1 - 0.73 10.5 7.1 0.28 11.8 1.7 2.3 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) WD40 PF00400.32 EOO04314.1 - 0.029 15.2 0.1 1.2 10.2 0.0 3.4 5 0 0 5 5 5 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO04314.1 - 0.075 13.3 0.0 1.5 9.2 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain CENP-T_C PF15511.6 EOO04316.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EOO04316.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EOO04316.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EOO04316.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EOO04316.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EOO04316.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EOO04316.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EOO04316.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 EOO04316.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region VEFS-Box PF09733.9 EOO04317.1 - 5.2e-12 45.7 0.1 1e-11 44.8 0.1 1.4 1 0 0 1 1 1 1 VEFS-Box of polycomb protein zf-C2H2_4 PF13894.6 EOO04317.1 - 3.8 8.6 6.3 2.4 9.2 0.5 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Molybdopterin PF00384.22 EOO04318.1 - 2e-75 254.4 0.1 1.8e-73 248.0 0.1 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 EOO04318.1 - 1.9e-19 70.1 0.1 7.7e-19 68.1 0.0 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 EOO04318.1 - 2.3e-17 62.2 0.2 2.3e-17 62.2 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region TPP_enzyme_M PF00205.22 EOO04318.1 - 0.0017 18.1 0.0 0.083 12.6 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 EOO04318.1 - 0.1 12.4 1.1 2.9 7.8 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.11 EOO04318.1 - 0.22 11.6 2.0 2.9 8.1 2.0 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_6 PF12837.7 EOO04318.1 - 0.34 11.1 2.4 0.45 10.7 1.0 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain AMP-binding PF00501.28 EOO04319.1 - 1.5e-87 293.9 0.2 1.9e-87 293.6 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EOO04319.1 - 3.7e-26 91.9 0.8 1e-24 87.3 0.6 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EOO04319.1 - 9.1e-19 67.1 0.5 2.4e-18 65.8 0.5 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 EOO04319.1 - 0.13 12.3 0.0 0.66 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Esterase_phd PF10503.9 EOO04320.1 - 7.1e-14 51.8 0.0 8.7e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EOO04320.1 - 7.7e-06 25.5 0.6 9.5e-06 25.2 0.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EOO04320.1 - 0.0035 17.0 0.4 0.0041 16.8 0.4 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 EOO04320.1 - 0.011 15.4 1.6 0.022 14.4 1.6 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S51 PF03575.17 EOO04320.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 BAAT_C PF08840.11 EOO04320.1 - 0.015 15.2 0.3 0.021 14.7 0.3 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 EOO04320.1 - 0.028 14.2 0.4 0.061 13.1 0.1 1.6 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EOO04320.1 - 0.08 12.8 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cofilin_ADF PF00241.20 EOO04321.1 - 8.9e-41 138.5 0.3 1e-40 138.3 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein AAA PF00004.29 EOO04323.1 - 1e-35 123.0 0.0 6.3e-34 117.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EOO04323.1 - 1.2e-09 37.8 0.1 3e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Mg_chelatase PF01078.21 EOO04323.1 - 2.3e-05 23.9 0.1 0.00018 20.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EOO04323.1 - 8.1e-05 22.7 0.0 0.0023 17.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EOO04323.1 - 8.9e-05 22.8 0.1 0.0039 17.5 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 EOO04323.1 - 0.00011 22.6 0.0 0.0013 19.1 0.0 2.7 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EOO04323.1 - 0.00017 21.4 0.0 0.0004 20.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 EOO04323.1 - 0.0002 21.1 0.0 0.00043 20.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Hydin_ADK PF17213.3 EOO04323.1 - 0.0014 18.9 0.4 0.061 13.6 0.0 2.4 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_5 PF07728.14 EOO04323.1 - 0.002 18.1 0.1 0.0057 16.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EOO04323.1 - 0.0047 17.5 0.0 0.015 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EOO04323.1 - 0.0055 17.1 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 EOO04323.1 - 0.0069 16.6 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EOO04323.1 - 0.0072 16.6 0.1 0.035 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 EOO04323.1 - 0.011 15.2 0.0 0.072 12.5 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein AAA_3 PF07726.11 EOO04323.1 - 0.011 15.6 0.1 0.16 11.8 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EOO04323.1 - 0.022 14.5 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EOO04323.1 - 0.027 14.0 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EOO04323.1 - 0.035 13.8 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EOO04323.1 - 0.062 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_2 PF07724.14 EOO04323.1 - 0.066 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_11 PF13086.6 EOO04323.1 - 0.074 12.8 0.2 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EOO04323.1 - 0.076 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EOO04323.1 - 0.1 12.2 0.0 0.33 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EOO04323.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 EOO04323.1 - 0.15 12.2 0.0 0.48 10.5 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain GYF PF02213.16 EOO04324.1 - 5.7e-11 41.9 0.8 1.2e-10 40.9 0.8 1.5 1 0 0 1 1 1 1 GYF domain RNA_pol_Rpb1_5 PF04998.17 EOO04325.1 - 1.6e-87 293.4 0.1 2.7e-87 292.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EOO04325.1 - 5e-69 231.8 0.4 1.2e-68 230.5 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EOO04325.1 - 8.7e-33 113.5 0.0 3.4e-32 111.6 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EOO04325.1 - 1.7e-16 60.1 0.6 6.9e-16 58.1 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 EOO04325.1 - 1.8e-07 30.8 2.4 1.9e-06 27.4 0.6 3.4 4 1 0 4 4 4 1 RNA polymerase Rpb1, domain 1 Nop14 PF04147.12 EOO04325.1 - 6.2 4.9 12.4 12 4.0 12.4 1.3 1 0 0 1 1 1 0 Nop14-like family BOP1NT PF08145.12 EOO04326.1 - 5.2e-107 357.6 8.9 8e-107 357.0 8.9 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EOO04326.1 - 3.1e-21 75.3 3.2 1.7e-10 41.3 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO04326.1 - 2.5e-07 30.9 0.1 0.00035 20.8 0.0 3.8 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EOO04326.1 - 0.0041 15.8 0.0 0.0067 15.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nop53 PF07767.11 EOO04326.1 - 0.037 13.4 0.3 0.037 13.4 0.3 2.3 2 1 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) PALB2_WD40 PF16756.5 EOO04326.1 - 0.096 11.6 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Rad21_Rec8_N PF04825.13 EOO04328.1 - 3e-37 127.1 0.0 5.4e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EOO04328.1 - 1.4e-08 33.9 0.3 5.6e-08 32.0 0.1 2.1 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein DnaJ PF00226.31 EOO04329.1 - 5.7e-11 42.4 0.6 1.7e-10 40.9 0.2 2.0 2 0 0 2 2 2 1 DnaJ domain E2_bind PF08825.10 EOO04330.1 - 2.8e-30 104.3 0.1 4.2e-30 103.7 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain ThiF PF00899.21 EOO04330.1 - 8.7e-08 31.8 0.2 1.2e-07 31.3 0.2 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 EOO04330.1 - 0.00087 19.8 0.0 0.0038 17.8 0.0 2.1 3 0 0 3 3 3 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 EOO04330.1 - 0.0093 15.9 1.2 0.87 9.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Prolamin_like PF05617.11 EOO04330.1 - 0.029 14.6 0.1 0.052 13.7 0.1 1.5 1 0 0 1 1 1 0 Prolamin-like Ecm33 PF12454.8 EOO04330.1 - 0.037 14.2 2.2 0.14 12.3 2.6 1.7 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein THOC7 PF05615.13 EOO04331.1 - 3.2e-41 140.7 4.7 3.2e-41 140.7 4.7 2.0 2 0 0 2 2 2 1 Tho complex subunit 7 DUF241 PF03087.14 EOO04331.1 - 0.043 13.6 5.6 0.075 12.9 5.6 1.4 1 1 0 1 1 1 0 Arabidopsis protein of unknown function Mod_r PF07200.13 EOO04331.1 - 0.13 12.3 10.2 0.19 11.8 10.2 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein RTBV_P46 PF06216.11 EOO04331.1 - 0.36 9.7 2.3 0.51 9.2 1.5 1.6 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein TBCA PF02970.16 EOO04332.1 - 9.7e-25 86.7 7.6 9.7e-25 86.7 7.6 1.8 1 1 1 2 2 2 1 Tubulin binding cofactor A Phage_lysis PF03245.13 EOO04332.1 - 0.013 15.6 0.6 0.013 15.6 0.6 2.2 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein DUF2408 PF10303.9 EOO04332.1 - 0.015 15.9 3.4 0.018 15.6 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Csm1_N PF18504.1 EOO04332.1 - 0.019 15.3 2.3 0.019 15.3 2.3 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain Flagellin_C PF00700.21 EOO04332.1 - 0.026 14.9 0.6 0.16 12.3 0.1 2.5 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region Cob_adeno_trans PF01923.18 EOO04332.1 - 0.1 12.7 1.8 0.43 10.7 0.3 2.0 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF1910 PF08928.10 EOO04332.1 - 0.15 12.1 2.0 0.22 11.5 2.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) DUF1151 PF06625.11 EOO04332.1 - 0.16 11.9 6.0 0.83 9.6 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1151) APC_N_CC PF16689.5 EOO04332.1 - 0.17 11.9 3.4 0.71 10.0 0.2 2.6 2 1 1 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain Spectrin PF00435.21 EOO04332.1 - 0.19 12.2 6.5 0.085 13.3 3.5 1.8 1 1 1 2 2 2 0 Spectrin repeat Metal_resist PF13801.6 EOO04332.1 - 0.53 10.5 5.3 0.33 11.2 2.6 1.7 1 1 0 2 2 2 0 Heavy-metal resistance ADIP PF11559.8 EOO04332.1 - 0.56 10.3 9.9 1.8 8.7 3.3 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4398 PF14346.6 EOO04332.1 - 0.68 10.6 12.2 0.44 11.2 3.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Spc7 PF08317.11 EOO04332.1 - 0.73 8.7 9.7 1.4 7.7 9.6 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 EOO04332.1 - 1.6 7.9 4.2 1.1 8.4 2.7 1.4 1 1 1 2 2 2 0 TMPIT-like protein ABC_tran_CTD PF16326.5 EOO04332.1 - 1.9 8.8 15.5 0.4 10.9 4.1 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain OmpH PF03938.14 EOO04332.1 - 2.7 8.3 15.4 20 5.5 15.4 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF16 PF01519.16 EOO04332.1 - 2.8 8.5 7.5 68 4.0 7.5 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF4407 PF14362.6 EOO04332.1 - 4.5 6.5 9.9 6.2 6.1 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CAS_C PF12026.8 EOO04333.1 - 0.03 14.4 2.8 0.04 14.0 2.8 1.1 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain NTP_transf_6 PF06042.11 EOO04333.1 - 0.043 13.7 0.6 0.051 13.4 0.6 1.1 1 0 0 1 1 1 0 Nucleotidyltransferase Nup54 PF13874.6 EOO04333.1 - 2.4 8.3 12.0 6 7.0 12.0 1.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Leo1 PF04004.13 EOO04334.1 - 7.1e-37 126.8 0.4 7.1e-37 126.8 0.4 1.7 2 0 0 2 2 2 1 Leo1-like protein NAD_binding_7 PF13241.6 EOO04334.1 - 0.18 12.3 0.2 0.38 11.2 0.2 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding NBD_C PF17042.5 EOO04334.1 - 0.29 11.6 1.8 0.59 10.6 1.8 1.5 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain DUF3237 PF11578.8 EOO04335.1 - 3.4e-31 108.1 0.1 3.8e-31 107.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Oxidored_FMN PF00724.20 EOO04336.1 - 9.3e-55 186.2 0.0 1.1e-54 186.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ThiF PF00899.21 EOO04337.1 - 7.5e-48 163.0 0.1 1e-47 162.6 0.1 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EOO04337.1 - 8.9e-05 22.6 0.4 0.00083 19.4 0.1 2.3 1 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EOO04337.1 - 0.021 15.1 0.4 0.13 12.6 0.3 2.2 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 EOO04337.1 - 0.023 15.1 0.0 0.039 14.4 0.0 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 EOO04337.1 - 0.025 15.1 0.1 0.064 13.8 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EOO04337.1 - 0.041 13.5 0.2 0.056 13.0 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PglD_N PF17836.1 EOO04337.1 - 0.045 14.4 0.8 0.083 13.5 0.6 1.6 1 1 0 1 1 1 0 PglD N-terminal domain TrkA_N PF02254.18 EOO04337.1 - 0.084 13.1 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EOO04337.1 - 0.089 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EOO04337.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Band_7 PF01145.25 EOO04338.1 - 5.5e-23 81.9 3.1 8.5e-23 81.3 3.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Zn_clus PF00172.18 EOO04339.1 - 2.3e-05 24.4 9.8 3.8e-05 23.7 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HBD PF18534.1 EOO04339.1 - 0.1 12.7 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Helical bundle domain RNA_pol_A_bac PF01000.26 EOO04340.1 - 2.7e-28 98.6 0.0 6e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EOO04340.1 - 4.6e-22 77.2 0.0 7.5e-22 76.5 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Prot_ATP_OB_N PF17758.1 EOO04340.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AlaDh_PNT_N PF05222.15 EOO04341.1 - 6.9e-28 97.6 0.0 1.2e-27 96.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EOO04341.1 - 0.0011 18.4 0.0 0.0022 17.3 0.0 1.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DNA_pol_phi PF04931.13 EOO04342.1 - 8.1e-205 682.3 24.4 1.2e-204 681.7 24.4 1.3 1 0 0 1 1 1 1 DNA polymerase phi CNOT1_TTP_bind PF16417.5 EOO04342.1 - 0.006 15.8 0.8 0.5 9.5 0.0 3.0 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 TTP binding domain Uteroglobin PF01099.17 EOO04342.1 - 0.022 15.1 0.0 0.022 15.1 0.0 3.0 3 0 0 3 3 3 0 Uteroglobin family DUF61 PF01886.16 EOO04342.1 - 0.022 14.8 0.6 0.15 12.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF61 EB1 PF03271.17 EOO04342.1 - 0.088 13.1 0.7 0.39 11.0 0.0 2.5 2 1 0 2 2 2 0 EB1-like C-terminal motif DUF1676 PF07898.13 EOO04342.1 - 0.17 11.9 3.2 0.46 10.5 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) NACHT_N PF17100.5 EOO04342.1 - 0.36 10.7 8.9 0.07 13.0 1.1 2.5 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase SDA1 PF05285.12 EOO04342.1 - 1.5 8.2 25.1 3.6 6.9 25.1 1.6 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EOO04342.1 - 3.6 6.8 31.7 0.031 13.6 22.4 2.1 2 0 0 2 2 2 0 BUD22 Matrilin_ccoil PF10393.9 EOO04343.1 - 0.0046 16.8 4.4 0.018 14.9 0.1 3.0 3 0 0 3 3 3 1 Trimeric coiled-coil oligomerisation domain of matrilin SesA PF17107.5 EOO04343.1 - 0.0055 16.9 3.3 0.0061 16.7 0.2 2.4 1 1 2 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases ZapD PF07072.11 EOO04343.1 - 0.031 14.0 4.8 0.043 13.6 3.8 1.7 1 1 0 1 1 1 0 Cell division protein Caudo_bapla_RBP PF08931.10 EOO04343.1 - 0.045 13.2 0.0 0.13 11.8 0.0 1.6 1 1 0 1 1 1 0 Receptor-binding protein of phage tail base-plate Siphoviridae, head ATG16 PF08614.11 EOO04343.1 - 0.076 13.2 20.2 0.11 12.7 20.2 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 EOO04343.1 - 0.086 11.9 7.7 0.12 11.5 7.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.12 EOO04343.1 - 0.3 9.6 0.4 0.3 9.6 0.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family KxDL PF10241.9 EOO04343.1 - 0.41 11.0 8.2 0.27 11.5 2.6 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF724 PF05266.14 EOO04343.1 - 0.96 9.2 18.4 1.1 9.1 12.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Fmp27_WPPW PF10359.9 EOO04343.1 - 1.6 7.5 15.9 0.13 11.1 4.9 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain UPF0242 PF06785.11 EOO04343.1 - 2.1 8.4 14.3 3.7 7.6 14.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin-6_N PF09177.11 EOO04343.1 - 2.4 8.8 14.1 15 6.2 3.0 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Cauli_AT PF03233.13 EOO04343.1 - 2.6 8.0 14.4 1.3 9.0 3.5 2.3 1 1 1 2 2 2 0 Aphid transmission protein LMBR1 PF04791.16 EOO04343.1 - 2.9 6.7 7.6 3.4 6.5 7.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Erp_C PF06780.11 EOO04343.1 - 4.8 7.2 12.5 1.2 9.2 8.4 2.0 2 1 0 2 2 2 0 Erp protein C-terminus V_ATPase_I PF01496.19 EOO04343.1 - 5.8 4.7 12.1 8 4.2 11.9 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family RhoGAP PF00620.27 EOO04344.1 - 2.1e-44 151.0 0.3 3.1e-44 150.5 0.3 1.2 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EOO04344.1 - 1.4e-12 48.0 0.0 2.8e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EOO04344.1 - 0.0061 16.8 0.1 0.029 14.7 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Mob1_phocein PF03637.17 EOO04345.1 - 1.8e-41 142.0 0.5 5.5e-41 140.4 0.5 1.7 1 1 0 1 1 1 1 Mob1/phocein family IU_nuc_hydro PF01156.19 EOO04348.1 - 1.1e-60 205.8 0.2 1.3e-60 205.6 0.2 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Elongin_A PF06881.11 EOO04349.1 - 9.5e-28 96.8 1.5 1.9e-27 95.8 1.5 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Proteasome PF00227.26 EOO04350.1 - 2e-47 161.2 0.5 4.7e-31 107.8 0.0 2.6 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.9 EOO04350.1 - 1.5e-11 43.8 1.2 1.5e-11 43.8 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature PITH PF06201.13 EOO04351.1 - 4.7e-38 130.8 0.0 7.5e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 EOO04351.1 - 1.1e-26 92.7 0.3 2.2e-26 91.8 0.3 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EOO04351.1 - 5e-07 30.1 1.0 3.2e-06 27.6 1.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EOO04351.1 - 4.4e-06 26.3 0.1 1e-05 25.1 0.0 1.5 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EOO04351.1 - 6.9e-06 26.3 0.0 0.012 15.9 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 EOO04351.1 - 0.0068 16.2 0.1 0.019 14.8 0.1 1.6 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 EOO04351.1 - 0.0076 16.2 0.1 0.024 14.6 0.1 1.8 1 1 0 1 1 1 1 AhpC/TSA family HyaE PF07449.11 EOO04351.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 EOO04351.1 - 0.083 12.6 0.2 0.31 10.8 0.2 1.9 1 1 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.6 EOO04351.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like PRA1 PF03208.19 EOO04353.1 - 9e-37 125.9 0.2 1.1e-36 125.6 0.2 1.1 1 0 0 1 1 1 1 PRA1 family protein Ni_hydr_CYTB PF01292.20 EOO04353.1 - 0.037 13.6 0.3 0.05 13.2 0.1 1.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 VirB3 PF05101.13 EOO04353.1 - 1.7 8.9 5.7 0.3 11.3 1.5 1.8 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein Fungal_trans_2 PF11951.8 EOO04354.1 - 0.0022 16.9 0.0 0.0037 16.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CorA PF01544.18 EOO04356.1 - 5.2e-36 124.4 0.3 2.7e-35 122.1 0.3 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Mannosyl_trans3 PF11051.8 EOO04357.1 - 1.2e-55 188.9 0.6 4.7e-33 114.7 0.1 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative ADH_zinc_N PF00107.26 EOO04358.1 - 2.2e-20 73.0 1.2 3.5e-20 72.3 1.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EOO04358.1 - 1e-15 59.0 0.2 3.2e-15 57.4 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EOO04358.1 - 0.00015 21.6 0.2 0.002 18.0 0.0 2.9 2 2 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain LEA_5 PF00477.17 EOO04358.1 - 0.0016 18.9 0.4 0.004 17.6 0.4 1.6 1 0 0 1 1 1 1 Small hydrophilic plant seed protein Ctr PF04145.15 EOO04359.1 - 0.21 12.2 0.6 0.39 11.3 0.6 1.3 1 1 0 1 1 1 0 Ctr copper transporter family DUF1509 PF07420.11 EOO04359.1 - 3.3 6.6 6.5 4.9 6.0 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) MFS_1 PF07690.16 EOO04360.1 - 1.2e-34 119.8 57.4 1.5e-31 109.6 28.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3042 PF11240.8 EOO04360.1 - 0.64 10.1 2.0 4.6 7.3 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) DUF4293 PF14126.6 EOO04360.1 - 4.2 7.6 12.8 8.5 6.6 0.0 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4293) CSTF2_hinge PF14327.6 EOO04361.1 - 9.4e-34 115.7 2.4 9.4e-34 115.7 2.4 1.7 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EOO04361.1 - 5.2e-22 77.4 0.0 8.8e-22 76.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EOO04361.1 - 1.8e-06 27.4 4.0 1.8e-06 27.4 4.0 3.3 4 0 0 4 4 4 1 Transcription termination and cleavage factor C-terminal L1R_F9L PF02442.17 EOO04361.1 - 0.13 12.1 0.2 0.33 10.8 0.1 1.7 2 0 0 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses Spo7_2_N PF15407.6 EOO04361.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_7 PF16367.5 EOO04361.1 - 0.17 12.0 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif DUF3135 PF11333.8 EOO04361.1 - 0.48 10.7 2.5 0.9 9.8 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) Sugar_tr PF00083.24 EOO04362.1 - 4.7e-63 213.6 25.7 5.4e-63 213.4 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO04362.1 - 2.1e-19 69.7 38.8 1.4e-13 50.5 17.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2207 PF09972.9 EOO04362.1 - 0.016 14.0 3.2 0.089 11.5 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4231 PF14015.6 EOO04362.1 - 6.6 7.3 8.0 0.78 10.2 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) COG4 PF08318.12 EOO04363.1 - 5.1e-127 423.6 0.0 7.5e-127 423.0 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein E1-E2_ATPase PF00122.20 EOO04363.1 - 1e-45 155.5 0.7 2.4e-45 154.3 0.7 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EOO04363.1 - 3.2e-28 98.7 0.1 6.7e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EOO04363.1 - 1.4e-19 71.3 1.2 2e-18 67.4 1.2 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EOO04363.1 - 6.1e-18 64.3 0.0 1.8e-17 62.8 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EOO04363.1 - 2.1e-12 46.9 0.0 5.1e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EOO04363.1 - 3.4e-05 23.7 0.9 7.4e-05 22.6 0.9 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HSCB_C PF07743.13 EOO04363.1 - 0.13 12.7 2.6 0.91 10.1 0.2 3.2 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain Dynamitin PF04912.14 EOO04364.1 - 1.9e-105 353.4 4.1 2.3e-105 353.1 4.1 1.0 1 0 0 1 1 1 1 Dynamitin Laminin_II PF06009.12 EOO04364.1 - 0.0013 18.7 12.6 0.022 14.8 0.1 4.8 4 1 1 5 5 5 1 Laminin Domain II FlgN PF05130.12 EOO04364.1 - 0.0014 19.2 1.4 0.0014 19.2 1.4 2.7 3 0 0 3 3 3 1 FlgN protein DASH_Spc19 PF08287.11 EOO04364.1 - 0.0091 15.9 1.9 0.0091 15.9 1.9 2.6 2 1 0 2 2 2 1 Spc19 FH2 PF02181.23 EOO04364.1 - 0.031 13.4 5.8 0.052 12.7 0.1 2.9 3 0 0 3 3 3 0 Formin Homology 2 Domain ATF7IP_BD PF16788.5 EOO04364.1 - 0.034 14.2 1.6 0.058 13.5 0.1 1.9 2 0 0 2 2 2 0 ATF-interacting protein binding domain Spore_III_AB PF09548.10 EOO04364.1 - 0.057 13.5 3.2 0.34 11.0 1.2 2.6 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) MRPL52 PF18699.1 EOO04364.1 - 0.059 13.6 0.6 0.059 13.6 0.6 2.8 3 0 0 3 3 3 0 Mitoribosomal protein mL52 ZapB PF06005.12 EOO04364.1 - 0.075 13.5 9.1 3.2 8.2 0.9 3.1 2 0 0 2 2 2 0 Cell division protein ZapB Phage_GP20 PF06810.11 EOO04364.1 - 0.078 12.8 12.5 0.066 13.0 2.3 3.3 3 0 0 3 3 3 0 Phage minor structural protein GP20 Wtap PF17098.5 EOO04364.1 - 0.095 12.6 4.5 3.5 7.6 0.0 2.8 3 1 1 4 4 3 0 WTAP/Mum2p family Baculo_PEP_C PF04513.12 EOO04364.1 - 0.12 12.4 0.3 2.5 8.1 0.1 2.6 3 1 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG17 PF04108.12 EOO04364.1 - 0.18 10.9 6.8 0.21 10.7 0.4 2.6 2 1 0 2 2 2 0 Autophagy protein Apg17 YabA PF06156.13 EOO04364.1 - 0.19 12.3 3.3 25 5.6 0.0 3.1 3 0 0 3 3 3 0 Initiation control protein YabA Cytochrom_B562 PF07361.11 EOO04364.1 - 0.21 12.3 9.0 2.8 8.6 0.2 3.3 3 0 0 3 3 3 0 Cytochrome b562 DUF2203 PF09969.9 EOO04364.1 - 0.36 11.6 10.4 20 5.9 0.1 3.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) ATP-synt_E PF05680.12 EOO04364.1 - 1.1 9.7 6.7 0.47 10.8 1.5 2.5 2 0 0 2 2 2 0 ATP synthase E chain Tropomyosin_1 PF12718.7 EOO04364.1 - 2.1 8.5 15.0 3.4 7.8 2.4 3.4 3 0 0 3 3 3 0 Tropomyosin like OmpH PF03938.14 EOO04364.1 - 2.5 8.4 11.4 5.4 7.4 2.9 3.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 EOO04364.1 - 3.5 8.2 20.9 2.1 8.9 1.4 3.3 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF1451 PF07295.11 EOO04364.1 - 4.9 7.2 6.5 6.4 6.8 0.4 2.6 3 0 0 3 3 3 0 Zinc-ribbon containing domain COG2 PF06148.11 EOO04364.1 - 7.8 6.6 7.6 11 6.1 0.5 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 YkyA PF10368.9 EOO04364.1 - 9.6 5.8 12.3 1.5 8.5 0.3 3.2 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein SURF4 PF02077.15 EOO04365.1 - 9.6e-100 333.6 7.7 1.1e-99 333.4 7.7 1.0 1 0 0 1 1 1 1 SURF4 family Halogen_Hydrol PF10112.9 EOO04365.1 - 3.8 7.5 6.4 14 5.6 2.1 2.7 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein CbiQ PF02361.16 EOO04365.1 - 5.3 6.6 14.2 0.48 10.0 5.4 2.2 2 0 0 2 2 2 0 Cobalt transport protein DUF1129 PF06570.11 EOO04365.1 - 6.5 6.2 7.4 0.59 9.6 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Lipase_GDSL_2 PF13472.6 EOO04366.1 - 3e-22 79.9 4.9 5e-22 79.1 4.9 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EOO04366.1 - 5.6e-10 39.5 0.0 9.4e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF72 PF01904.18 EOO04366.1 - 0.049 13.7 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF72 Adhesin_P1 PF03257.13 EOO04366.1 - 0.074 13.6 0.1 0.3 11.6 0.1 2.0 1 0 0 1 1 1 0 Mycoplasma adhesin P1 G-patch PF01585.23 EOO04368.1 - 0.00051 19.9 0.0 0.0015 18.4 0.0 1.8 1 1 0 1 1 1 1 G-patch domain BTB PF00651.31 EOO04368.1 - 0.00061 20.0 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DnaJ PF00226.31 EOO04370.1 - 2.4e-19 69.2 0.9 3.7e-19 68.6 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 EOO04370.1 - 0.028 14.7 2.1 0.044 14.1 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Sugar_tr PF00083.24 EOO04371.1 - 2.7e-79 267.2 24.1 3.3e-79 266.9 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EOO04371.1 - 2.7e-16 59.5 32.2 2.7e-16 59.5 32.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2574 PF10836.8 EOO04371.1 - 0.0068 16.3 0.1 0.033 14.1 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2574) NAD_binding_10 PF13460.6 EOO04372.1 - 2.3e-23 83.0 0.9 3e-23 82.6 0.9 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EOO04372.1 - 1.7e-06 27.7 0.0 3.2e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO04372.1 - 0.0063 16.0 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EOO04372.1 - 0.021 13.9 0.4 0.06 12.4 0.0 1.9 2 1 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 EOO04372.1 - 0.088 12.0 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Glyco_hydro_3_C PF01915.22 EOO04373.1 - 1.6e-52 178.4 0.0 3.5e-52 177.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EOO04373.1 - 2.3e-19 69.3 2.2 8.3e-19 67.5 0.2 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF11 PF01345.18 EOO04373.1 - 0.015 15.6 0.2 0.033 14.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF11 PA14 PF07691.12 EOO04373.1 - 0.017 15.0 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 PA14 domain NPCBM_assoc PF10633.9 EOO04373.1 - 0.23 11.7 3.0 2.9 8.2 0.2 3.2 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase FAD_binding_4 PF01565.23 EOO04374.1 - 2.6e-21 75.8 1.2 5.6e-21 74.8 1.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EOO04374.1 - 2.5e-07 30.7 0.3 4.6e-07 29.8 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like BCNT PF07572.12 EOO04375.1 - 5.1e-24 84.2 2.5 1.1e-23 83.0 2.5 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development TIM PF00121.18 EOO04376.1 - 1.1e-85 286.9 0.1 1.3e-85 286.6 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 EOO04376.1 - 0.02 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 CutC family AA_kinase PF00696.28 EOO04377.1 - 3.1e-23 82.6 0.8 5e-23 81.9 0.8 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EOO04377.1 - 8.4e-18 64.1 0.1 1.5e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 PUA domain Lon_C PF05362.13 EOO04377.1 - 0.021 14.4 0.1 0.031 13.8 0.1 1.2 1 0 0 1 1 1 0 Lon protease (S16) C-terminal proteolytic domain AMP-binding PF00501.28 EOO04378.1 - 3.5e-06 25.9 0.0 4.5e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EOO04378.1 - 3.8e-05 24.6 0.2 7.6e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Dioxygenase_C PF00775.21 EOO04379.1 - 7.6e-47 159.1 0.0 9.3e-47 158.8 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EOO04379.1 - 2.3e-22 78.6 0.0 3.8e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EOO04379.1 - 0.0001 22.5 0.1 0.0029 17.8 0.0 2.4 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain Cytochrom_B561 PF03188.16 EOO04380.1 - 2.7e-06 27.5 6.1 2.7e-06 27.5 6.1 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 MAP17 PF15807.5 EOO04380.1 - 0.012 15.9 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4079 PF13301.6 EOO04380.1 - 0.032 14.4 12.1 0.14 12.3 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF2427 PF10348.9 EOO04380.1 - 0.037 13.8 5.5 0.12 12.2 5.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) Claudin_3 PF06653.11 EOO04380.1 - 0.044 13.7 0.5 0.044 13.7 0.5 1.7 2 0 0 2 2 2 0 Tight junction protein, Claudin-like AA_permease_C PF13906.6 EOO04380.1 - 0.078 13.1 1.3 0.078 13.1 1.3 2.6 4 0 0 4 4 4 0 C-terminus of AA_permease DUF998 PF06197.13 EOO04380.1 - 5 6.7 16.7 1 8.9 7.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF998) MFS_1 PF07690.16 EOO04381.1 - 1.1e-10 41.0 29.9 4.8e-06 25.7 4.3 4.0 2 1 2 4 4 4 2 Major Facilitator Superfamily MFS_2 PF13347.6 EOO04381.1 - 1.7e-10 40.0 4.8 1.7e-10 40.0 4.8 3.1 3 0 0 3 3 3 2 MFS/sugar transport protein LRR19-TM PF15176.6 EOO04381.1 - 0.2 11.6 0.4 0.95 9.5 0.4 2.1 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Pkinase PF00069.25 EOO04382.1 - 8e-71 238.5 0.0 1e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO04382.1 - 3.2e-43 147.9 0.0 4.3e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EOO04382.1 - 2.4e-07 30.3 0.0 1.6e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EOO04382.1 - 0.001 18.4 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EOO04382.1 - 0.014 14.3 4.0 0.015 14.2 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 EOO04382.1 - 0.017 14.7 0.0 0.057 13.0 0.0 1.7 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 EOO04382.1 - 0.063 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EOO04382.1 - 0.071 12.6 0.0 0.2 11.2 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 EOO04382.1 - 0.1 11.4 1.0 0.18 10.5 1.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase Nnf1 PF03980.14 EOO04383.1 - 3.5e-35 120.7 0.9 7.2e-35 119.7 0.9 1.5 1 0 0 1 1 1 1 Nnf1 LOH1CR12 PF10158.9 EOO04383.1 - 0.012 15.7 0.4 0.034 14.2 0.2 1.8 2 0 0 2 2 2 0 Tumour suppressor protein Dynamin_M PF01031.20 EOO04383.1 - 0.019 14.2 0.4 4.3 6.5 0.0 2.1 2 0 0 2 2 2 0 Dynamin central region YqjK PF13997.6 EOO04383.1 - 0.098 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 YqjK-like protein Med21 PF11221.8 EOO04383.1 - 0.13 12.5 0.5 0.13 12.5 0.5 2.5 2 1 0 2 2 2 0 Subunit 21 of Mediator complex Rx_N PF18052.1 EOO04383.1 - 1.2 9.5 3.8 1.4 9.3 1.1 2.2 2 0 0 2 2 2 0 Rx N-terminal domain adh_short PF00106.25 EOO04384.1 - 5.2e-26 91.3 0.1 9.8e-26 90.4 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO04384.1 - 1.8e-19 70.2 0.1 2.5e-19 69.8 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.19 EOO04384.1 - 0.018 14.4 0.1 0.071 12.4 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Acyltransferase PF01553.21 EOO04385.1 - 1.1e-15 57.4 0.0 2.8e-15 56.1 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase Tic110 PF16940.5 EOO04385.1 - 0.072 11.6 0.0 0.097 11.1 0.0 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter PH_9 PF15410.6 EOO04386.1 - 0.00039 20.8 0.0 0.00051 20.4 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PrpF PF04303.13 EOO04387.1 - 1.6e-79 267.5 1.5 1.8e-79 267.4 1.5 1.0 1 0 0 1 1 1 1 PrpF protein SRP9-21 PF05486.12 EOO04388.1 - 2.4e-35 120.8 0.0 3.2e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) K_channel_TID PF07941.11 EOO04388.1 - 4.2 7.9 10.3 3.5 8.1 3.4 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain PX PF00787.24 EOO04389.1 - 3.4e-19 68.9 0.0 1.4e-18 66.9 0.0 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 EOO04389.1 - 8.1e-14 51.7 8.3 2.8e-07 30.3 0.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like adh_short_C2 PF13561.6 EOO04390.1 - 8.4e-42 143.3 0.5 1.1e-41 142.9 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO04390.1 - 3.1e-40 137.7 0.1 3.8e-40 137.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO04390.1 - 0.016 15.1 1.0 0.066 13.1 1.0 1.8 1 1 0 1 1 1 0 KR domain Epimerase PF01370.21 EOO04390.1 - 0.02 14.4 0.0 0.033 13.6 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EOO04390.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase SNF5 PF04855.12 EOO04391.1 - 4.8e-67 226.2 0.2 5.8e-66 222.7 0.2 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 PET117 PF15786.5 EOO04391.1 - 7.7 6.9 5.8 4.2 7.7 0.4 2.9 3 0 0 3 3 3 0 PET assembly of cytochrome c oxidase, mitochondrial CoA_transf_3 PF02515.17 EOO04392.1 - 1.5e-28 100.0 0.0 2e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III GH131_N PF18271.1 EOO04393.1 - 5.1e-65 219.7 4.1 5.9e-65 219.5 4.1 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Rdx PF10262.9 EOO04394.1 - 4.5e-20 71.6 0.0 6.8e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Rdx family Ribosomal_60s PF00428.19 EOO04394.1 - 6.5 7.4 13.3 0.73 10.5 2.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2457 PF10446.9 EOO04396.1 - 1.1e-182 608.4 26.2 1.1e-182 608.4 26.2 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) TFIIA PF03153.13 EOO04396.1 - 0.079 12.9 18.5 0.0097 16.0 13.7 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3499 PF12005.8 EOO04396.1 - 3 8.5 6.3 1.1 9.9 2.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3499) Peptidase_M24 PF00557.24 EOO04397.1 - 6.1e-07 29.3 0.0 7.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4258 PF14076.6 EOO04397.1 - 0.091 13.2 0.4 1.6 9.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) SCA7 PF08313.12 EOO04398.1 - 2.8e-32 110.4 0.1 1e-31 108.6 0.1 2.0 1 0 0 1 1 1 1 SCA7, zinc-binding domain CDC45 PF02724.14 EOO04398.1 - 0.056 11.7 11.1 0.065 11.5 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Omega-toxin PF06357.11 EOO04398.1 - 0.072 12.9 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Omega-atracotoxin Presenilin PF01080.17 EOO04398.1 - 6.9 5.3 7.7 9.4 4.9 7.7 1.2 1 0 0 1 1 1 0 Presenilin Metallophos PF00149.28 EOO04399.1 - 4e-40 138.5 0.1 5.2e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EOO04399.1 - 3.2e-23 81.9 1.8 4.7e-23 81.4 1.0 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain TPR_1 PF00515.28 EOO04401.1 - 2.8e-27 93.4 15.4 8.7e-05 22.2 0.0 11.9 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_2 PF07719.17 EOO04401.1 - 2.9e-24 83.2 23.3 0.0077 16.3 0.0 12.4 14 0 0 14 14 12 7 Tetratricopeptide repeat TPR_19 PF14559.6 EOO04401.1 - 7.9e-21 74.3 12.1 0.014 15.9 0.0 9.7 9 1 1 10 10 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 EOO04401.1 - 2.9e-18 64.5 11.2 4.5e-05 23.2 0.0 9.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 EOO04401.1 - 4.5e-16 57.6 23.5 0.011 15.9 0.0 11.9 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_12 PF13424.6 EOO04401.1 - 2.4e-14 53.4 25.1 0.0027 17.9 0.0 10.3 8 4 2 11 11 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 EOO04401.1 - 1.3e-11 44.9 19.2 0.1 13.2 0.0 10.0 10 2 1 11 11 11 3 Tetratricopeptide repeat TPR_14 PF13428.6 EOO04401.1 - 1.8e-10 40.7 31.2 0.0071 17.1 0.0 11.9 14 2 1 15 15 13 2 Tetratricopeptide repeat TPR_17 PF13431.6 EOO04401.1 - 2.1e-10 40.2 6.9 0.037 14.4 0.2 10.0 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_6 PF13174.6 EOO04401.1 - 6.2e-10 39.1 19.4 0.012 16.2 0.0 10.8 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_10 PF13374.6 EOO04401.1 - 7.5e-08 32.0 6.4 0.34 10.8 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 EOO04401.1 - 4.9e-07 29.3 15.1 0.063 13.0 0.0 6.8 8 0 0 8 8 8 3 TPR repeat ANAPC3 PF12895.7 EOO04401.1 - 0.02 15.1 11.9 0.67 10.2 0.2 5.9 6 1 1 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 Pkinase PF00069.25 EOO04402.1 - 4.7e-69 232.7 2.5 4.6e-68 229.4 2.5 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO04402.1 - 1.4e-53 181.8 0.2 2.5e-53 181.0 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EOO04402.1 - 2.4e-24 85.5 0.4 6.8e-24 84.0 0.0 2.0 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 EOO04402.1 - 3.4e-07 29.9 0.0 5.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 EOO04402.1 - 1.7e-06 28.4 0.1 6.6e-06 26.5 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Pkinase_fungal PF17667.1 EOO04402.1 - 2.8e-06 26.4 0.2 6.4e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase PH PF00169.29 EOO04402.1 - 0.0023 18.4 0.0 0.005 17.3 0.0 1.6 1 0 0 1 1 1 1 PH domain Seadorna_VP7 PF07387.11 EOO04402.1 - 0.022 13.8 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EOO04402.1 - 0.041 12.8 0.6 0.071 12.0 0.6 1.4 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EOO04402.1 - 0.047 13.6 0.2 0.047 13.6 0.2 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 EOO04402.1 - 0.077 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA PF03153.13 EOO04402.1 - 4.1 7.3 14.2 6.4 6.7 14.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cellulase PF00150.18 EOO04403.1 - 1e-18 67.8 0.5 2e-18 66.8 0.5 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) B12-binding PF02310.19 EOO04403.1 - 0.015 15.4 0.0 4.9 7.2 0.0 2.5 2 0 0 2 2 2 0 B12 binding domain Peptidase_M76 PF09768.9 EOO04404.1 - 9.4e-70 233.8 1.6 1.1e-69 233.5 1.6 1.1 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_M91 PF14891.6 EOO04404.1 - 0.073 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Effector protein SprT-like PF10263.9 EOO04404.1 - 0.11 12.3 1.8 0.2 11.5 0.9 1.8 1 1 1 2 2 2 0 SprT-like family SpoIIP PF07454.11 EOO04405.1 - 0.083 12.3 0.7 0.13 11.7 0.7 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AAA PF00004.29 EOO04407.1 - 2.4e-45 154.2 0.0 1.1e-41 142.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EOO04407.1 - 1.5e-09 37.5 0.0 7.1e-09 35.3 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EOO04407.1 - 1.7e-05 25.0 0.0 5.8e-05 23.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EOO04407.1 - 2.6e-05 24.1 0.0 5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 EOO04407.1 - 0.00016 22.1 2.4 0.0003 21.2 0.2 2.6 2 1 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.6 EOO04407.1 - 0.00058 20.4 0.2 0.046 14.3 0.0 3.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EOO04407.1 - 0.00073 19.5 0.0 0.0029 17.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EOO04407.1 - 0.001 19.2 0.2 0.075 13.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EOO04407.1 - 0.0031 16.8 0.0 0.0066 15.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EOO04407.1 - 0.0034 17.7 0.1 0.091 13.0 0.1 2.8 1 1 0 1 1 1 1 AAA domain Bromodomain PF00439.25 EOO04407.1 - 0.0053 16.8 0.1 0.015 15.4 0.1 1.7 1 0 0 1 1 1 1 Bromodomain RNA_helicase PF00910.22 EOO04407.1 - 0.022 15.1 0.0 0.086 13.2 0.0 2.1 2 0 0 2 2 1 0 RNA helicase RuvB_N PF05496.12 EOO04407.1 - 0.029 14.1 0.0 0.079 12.7 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 EOO04407.1 - 0.039 14.5 0.0 0.65 10.5 0.0 3.0 2 1 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.21 EOO04407.1 - 0.06 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EOO04407.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EOO04407.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Pkinase PF00069.25 EOO04408.1 - 5.2e-78 262.1 0.0 6.1e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO04408.1 - 2.2e-37 128.8 0.0 2.9e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EOO04408.1 - 0.0011 18.0 0.0 0.03 13.3 0.0 2.2 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EOO04408.1 - 0.037 13.9 0.9 0.12 12.3 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EOO04408.1 - 0.051 12.9 0.1 0.11 11.8 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EOO04408.1 - 0.11 11.7 0.0 0.34 10.2 0.0 1.8 2 0 0 2 2 2 0 Kinase-like WSC PF01822.19 EOO04409.1 - 1.3e-41 140.7 25.9 3.5e-21 75.2 10.4 2.2 2 0 0 2 2 2 2 WSC domain TruB-C_2 PF09157.11 EOO04410.1 - 0.029 14.4 0.0 2.4 8.3 0.0 2.6 2 0 0 2 2 2 0 Pseudouridine synthase II TruB, C-terminal PPR_2 PF13041.6 EOO04410.1 - 0.047 13.9 0.1 2.9 8.1 0.0 3.0 3 0 0 3 3 3 0 PPR repeat family PKI PF02827.16 EOO04411.1 - 1.2 9.4 7.0 0.39 11.0 0.8 3.1 3 0 0 3 3 3 0 cAMP-dependent protein kinase inhibitor Mito_carr PF00153.27 EOO04413.1 - 1.3e-40 137.3 2.1 4.9e-20 71.2 0.0 2.7 3 0 0 3 3 3 2 Mitochondrial carrier protein HEAT_2 PF13646.6 EOO04414.1 - 0.00027 21.2 1.3 4.8 7.6 0.0 5.3 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.22 EOO04414.1 - 0.0007 19.6 4.6 20 5.8 0.0 6.5 7 0 0 7 7 7 1 HEAT repeat Nitr_red_assoc PF09655.10 EOO04414.1 - 0.21 12.2 4.3 1.4 9.5 0.1 3.0 3 0 0 3 3 3 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) DUF3734 PF12536.8 EOO04414.1 - 0.44 10.9 3.5 0.53 10.7 0.1 2.9 3 0 0 3 3 3 0 Patatin phospholipase HEAT_EZ PF13513.6 EOO04414.1 - 1.9 9.1 4.4 24 5.6 0.0 4.8 6 0 0 6 6 6 0 HEAT-like repeat NOA36 PF06524.12 EOO04414.1 - 8.6 5.6 9.3 20 4.4 9.3 1.5 1 0 0 1 1 1 0 NOA36 protein PUF PF00806.19 EOO04415.1 - 7.6e-28 94.6 0.0 3.1e-05 23.4 0.0 6.0 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 EOO04415.1 - 4.8e-14 51.9 0.0 1.1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spt20 PF12090.8 EOO04415.1 - 0.012 15.3 10.0 0.027 14.1 10.0 1.6 1 0 0 1 1 1 0 Spt20 family CDK2AP PF09806.9 EOO04415.1 - 5.8 6.9 12.8 0.14 12.2 5.7 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein MAPEG PF01124.18 EOO04416.1 - 3.2e-14 53.0 1.8 3.9e-14 52.7 1.8 1.1 1 0 0 1 1 1 1 MAPEG family Pkinase PF00069.25 EOO04417.1 - 1.1e-46 159.4 0.0 1.7e-46 158.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EOO04417.1 - 1.9e-23 83.1 0.0 2.9e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EOO04417.1 - 9.7e-05 22.4 0.1 0.00019 21.5 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EOO04417.1 - 0.0017 18.0 0.3 0.0046 16.6 0.3 1.6 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EOO04417.1 - 0.46 10.0 2.2 0.25 10.9 0.2 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase RRM_1 PF00076.22 EOO04418.1 - 1.1e-61 204.6 0.0 1.7e-21 75.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EOO04418.1 - 3e-10 39.8 0.0 9.6e-06 25.2 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EOO04418.1 - 2.2e-09 37.1 0.0 0.0071 16.2 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EOO04418.1 - 6.4e-06 26.1 0.1 0.076 13.0 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 EOO04418.1 - 0.0009 19.4 0.0 0.29 11.4 0.0 2.4 2 0 0 2 2 2 1 RRM-like domain RRM_7 PF16367.5 EOO04418.1 - 0.00099 19.2 0.0 1.1 9.5 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif Cas_Cas2CT1978 PF09707.10 EOO04418.1 - 0.0013 18.8 0.0 0.49 10.5 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) Limkain-b1 PF11608.8 EOO04418.1 - 0.011 15.8 0.0 8.3 6.6 0.0 3.4 3 0 0 3 3 3 0 Limkain b1 Acetyltransf_10 PF13673.7 EOO04418.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SET_assoc PF11767.8 EOO04418.1 - 0.18 11.5 0.0 21 4.8 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_3 PF08777.11 EOO04418.1 - 0.18 11.8 0.0 1.8 8.7 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif WD40 PF00400.32 EOO04419.1 - 2.2e-17 63.1 5.5 1e-07 32.5 0.1 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EOO04419.1 - 0.00016 21.9 0.0 3.7 7.9 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain L51_S25_CI-B8 PF05047.16 EOO04420.1 - 1e-14 54.2 0.0 1.5e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain 5_nucleotid_C PF02872.18 EOO04422.1 - 0.0046 17.2 0.0 0.0081 16.4 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain RNA_pol_I_A49 PF06870.12 EOO04424.1 - 1.1e-93 314.2 0.5 1.5e-93 313.7 0.5 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor TetR_C_14 PF17754.1 EOO04424.1 - 0.97 9.4 3.3 0.79 9.7 0.6 2.2 2 1 0 2 2 2 0 MftR C-terminal domain RTA1 PF04479.13 EOO04425.1 - 3.4e-66 222.8 8.6 3.4e-66 222.8 8.6 1.4 2 0 0 2 2 2 1 RTA1 like protein Biotin_lipoyl PF00364.22 EOO04427.1 - 5.7e-19 67.7 2.2 1.1e-18 66.8 2.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EOO04427.1 - 1.3e-09 38.2 0.0 5e-09 36.4 0.0 2.1 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EOO04427.1 - 5.8e-05 22.8 0.2 0.00038 20.2 0.0 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like Suf PF05843.14 EOO04427.1 - 0.082 12.9 0.7 0.21 11.5 0.7 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1631 PF07793.11 EOO04427.1 - 0.11 10.9 1.3 0.15 10.4 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) HlyD_3 PF13437.6 EOO04427.1 - 0.12 13.1 0.6 1.5 9.6 0.0 2.6 2 1 1 3 3 3 0 HlyD family secretion protein FAM220 PF15487.6 EOO04427.1 - 0.33 10.5 1.3 0.61 9.7 1.3 1.4 1 0 0 1 1 1 0 FAM220 family MIF4G PF02854.19 EOO04429.1 - 4.4e-53 180.1 0.0 9.8e-53 178.9 0.0 1.6 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.8 EOO04429.1 - 3.4e-22 78.4 0.7 9e-22 77.0 0.7 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Arf PF00025.21 EOO04430.1 - 3.6e-66 221.9 0.0 4.1e-66 221.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EOO04430.1 - 1.6e-10 40.7 0.0 6.2e-07 28.9 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EOO04430.1 - 1.9e-07 31.3 0.0 6.5e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EOO04430.1 - 2.8e-07 30.3 0.0 3.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EOO04430.1 - 2.9e-07 30.1 0.0 3.8e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EOO04430.1 - 3.4e-07 30.3 0.0 4.5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EOO04430.1 - 1.1e-05 24.9 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EOO04430.1 - 0.0014 18.2 0.1 0.054 13.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain CENP-M PF11111.8 EOO04430.1 - 0.12 11.6 0.0 0.35 10.0 0.0 1.6 2 0 0 2 2 2 0 Centromere protein M (CENP-M) cobW PF02492.19 EOO04430.1 - 0.18 11.4 0.0 8.9 5.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Na_H_Exchanger PF00999.21 EOO04431.1 - 1.5e-71 241.2 31.9 1.9e-71 240.9 31.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM PF03929.16 EOO04431.1 - 0.017 14.8 2.1 0.044 13.4 2.1 1.6 1 0 0 1 1 1 0 PepSY-associated TM region DUF3149 PF11346.8 EOO04431.1 - 0.052 13.2 0.2 0.052 13.2 0.2 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3149) DUF4407 PF14362.6 EOO04431.1 - 0.14 11.5 0.8 0.47 9.8 0.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribonuc_red_sm PF00268.21 EOO04432.1 - 3.9e-122 407.1 1.0 4.7e-122 406.8 1.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain U1snRNP70_N PF12220.8 EOO04433.1 - 2.8e-27 95.2 1.7 5.6e-27 94.2 1.7 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EOO04433.1 - 1.3e-10 40.9 0.2 2.1e-09 37.0 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EOO04433.1 - 0.0025 17.9 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif HET PF06985.11 EOO04434.1 - 5.3e-15 56.0 0.0 1e-14 55.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TIP41 PF04176.13 EOO04435.1 - 9.1e-68 227.1 0.0 1.1e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family DUF3581 PF12119.8 EOO04435.1 - 0.088 12.2 0.1 10 5.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3581) RRM_1 PF00076.22 EOO04436.1 - 0.00017 21.3 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulfotransfer_1 PF00685.27 EOO04437.1 - 0.069 12.6 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain ADH_N PF08240.12 EOO04438.1 - 4.3e-23 81.3 1.8 1e-22 80.1 1.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EOO04438.1 - 5.2e-10 39.4 0.0 2.4e-08 34.0 0.0 2.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EOO04438.1 - 2.1e-05 24.0 0.1 3.5e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EOO04438.1 - 2.2e-05 23.9 0.1 3.3e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EOO04438.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EOO04438.1 - 0.022 14.9 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RgpF PF05045.12 EOO04439.1 - 0.031 13.0 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Rhamnan synthesis protein F Dynamin_N PF00350.23 EOO04440.1 - 4.7e-07 30.0 1.0 1e-06 28.9 0.0 2.1 2 1 1 3 3 3 1 Dynamin family DUF2489 PF10675.9 EOO04440.1 - 0.048 13.6 0.3 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) ADIP PF11559.8 EOO04440.1 - 0.078 13.1 3.1 0.15 12.2 0.5 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 EOO04440.1 - 0.083 13.4 0.3 0.083 13.4 0.3 2.9 4 0 0 4 4 4 0 Apg6 coiled-coil region DUF4763 PF15960.5 EOO04440.1 - 0.75 9.1 6.0 0.18 11.1 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) UPF0449 PF15136.6 EOO04440.1 - 1.7 9.2 5.2 24 5.4 0.0 3.2 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 BLOC1_2 PF10046.9 EOO04440.1 - 1.7 9.0 4.8 9.1 6.7 0.8 3.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 EOO04440.1 - 3.2 6.8 6.4 3.3 6.7 1.4 2.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 adh_short PF00106.25 EOO04441.1 - 6e-31 107.4 0.1 8.9e-31 106.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EOO04441.1 - 2e-16 60.3 0.4 3e-16 59.7 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EOO04441.1 - 0.007 16.3 0.1 0.011 15.6 0.1 1.4 1 1 0 1 1 1 1 KR domain NTF2 PF02136.20 EOO04442.1 - 4.4e-25 88.6 0.5 6.5e-25 88.0 0.5 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EOO04442.1 - 3.5e-06 26.7 0.1 6.1e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4112 PF13430.6 EOO04443.1 - 1.9e-36 124.5 0.5 2.6e-36 124.1 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF4810 PF16068.5 EOO04443.1 - 0.16 12.6 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4810) PHD PF00628.29 EOO04444.1 - 4.1e-14 52.2 19.1 2.9e-08 33.5 9.7 2.4 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 EOO04444.1 - 0.0022 18.2 3.4 0.024 14.9 0.3 2.5 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-PHD-like PF15446.6 EOO04444.1 - 0.03 13.9 9.6 0.036 13.7 2.4 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 EOO04444.1 - 0.32 10.9 10.9 0.63 10.0 0.8 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 EOO04444.1 - 2.3 8.4 12.2 1.4 9.1 0.5 2.7 2 1 0 2 2 2 0 KIAA1045 RING finger Prok-RING_1 PF14446.6 EOO04444.1 - 2.6 8.1 15.5 0.54 10.2 2.3 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 mRNA_cap_enzyme PF01331.19 EOO04446.1 - 7.8e-57 192.3 0.1 1e-56 191.9 0.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EOO04446.1 - 4e-32 111.1 0.0 7.1e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EOO04446.1 - 2e-08 34.1 0.0 0.00011 21.9 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 EOO04446.1 - 0.00013 22.4 0.1 0.0002 21.7 0.1 1.3 1 0 0 1 1 1 1 RNA ligase SH3_1 PF00018.28 EOO04447.1 - 2.6e-05 23.7 0.0 5.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Phage_GPD PF05954.11 EOO04447.1 - 0.0059 15.9 2.4 0.014 14.7 2.4 1.5 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) SH3_9 PF14604.6 EOO04447.1 - 0.043 13.7 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain DUF3336 PF11815.8 EOO04448.1 - 1.2e-52 177.3 6.9 1.9e-52 176.7 6.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EOO04448.1 - 1.1e-18 68.1 0.1 8.3e-18 65.3 0.0 2.5 3 0 0 3 3 3 1 Patatin-like phospholipase zf-C2H2 PF00096.26 EOO04449.1 - 1.2e-07 31.8 20.0 1.8e-05 24.9 3.8 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EOO04449.1 - 1.4e-05 25.5 12.7 4e-05 24.1 2.3 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EOO04449.1 - 3.9e-05 23.9 3.8 3.9e-05 23.9 3.8 3.1 3 0 0 3 3 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EOO04449.1 - 0.00048 20.0 3.8 0.0017 18.3 1.8 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EOO04449.1 - 0.0014 18.8 1.0 0.0014 18.8 1.0 2.8 3 0 0 3 3 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 EOO04449.1 - 0.02 15.2 3.3 0.057 13.7 3.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 EOO04449.1 - 0.12 13.0 7.8 0.35 11.5 0.6 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-met PF12874.7 EOO04449.1 - 0.17 12.3 2.4 0.33 11.4 0.7 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 EOO04449.1 - 0.65 10.5 6.1 2.9 8.4 3.7 2.5 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 EOO04449.1 - 0.87 10.0 5.3 4.3 7.7 5.4 2.1 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.18 EOO04449.1 - 1.2 9.9 7.6 0.14 12.9 3.1 1.8 2 0 0 2 2 1 0 TRAF-type zinc finger DUF629 PF04780.12 EOO04449.1 - 1.9 6.9 5.0 2.5 6.5 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2HC_2 PF13913.6 EOO04449.1 - 5.7 7.0 5.9 0.99 9.4 1.4 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type G-gamma PF00631.22 EOO04450.1 - 2.7e-25 88.1 0.0 3.5e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 GGL domain PCI PF01399.27 EOO04451.1 - 3.9e-08 33.7 0.1 3.9e-08 33.7 0.1 2.8 3 0 0 3 3 3 1 PCI domain Cellulase PF00150.18 EOO04452.1 - 1.6e-14 54.1 5.8 2e-14 53.7 5.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Rad50_zn_hook PF04423.14 EOO04453.1 - 0.024 14.4 5.9 0.24 11.3 0.1 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF2256 PF10013.9 EOO04453.1 - 0.059 13.5 2.3 9.5 6.4 0.5 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DZR PF12773.7 EOO04453.1 - 0.15 12.1 3.4 0.71 9.9 1.4 2.6 2 1 0 2 2 2 0 Double zinc ribbon BIR PF00653.21 EOO04453.1 - 0.43 11.3 2.7 15 6.3 0.3 3.2 2 1 0 3 3 3 0 Inhibitor of Apoptosis domain GFA PF04828.14 EOO04453.1 - 0.57 10.5 3.0 3.7 8.0 0.3 3.0 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme E6 PF00518.17 EOO04453.1 - 2.8 8.4 7.8 2.9 8.4 0.4 2.9 2 1 1 3 3 3 0 Early Protein (E6) zinc_ribbon_9 PF14369.6 EOO04453.1 - 3.2 8.1 4.8 12 6.3 0.0 3.1 4 0 0 4 4 4 0 zinc-ribbon zf-ribbon_3 PF13248.6 EOO04453.1 - 6.3 6.4 7.3 9.8 5.7 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain RTA1 PF04479.13 EOO04454.1 - 3.5e-52 177.0 6.6 5.1e-52 176.5 6.6 1.2 1 0 0 1 1 1 1 RTA1 like protein Tnp_zf-ribbon_2 PF13842.6 EOO04455.1 - 2.3 9.1 8.4 3.7 8.4 8.4 1.3 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DNA_pol_B PF00136.21 EOO04456.1 - 2.1e-116 389.4 1.0 3.3e-116 388.7 1.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EOO04456.1 - 3.7e-70 235.4 0.0 6.6e-70 234.6 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EOO04456.1 - 3.5e-43 148.1 0.0 8.2e-43 146.8 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EOO04456.1 - 1.1e-25 89.4 9.7 5.3e-25 87.3 9.7 2.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 EOO04456.1 - 0.0041 16.0 0.1 0.028 13.3 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral PurL_C PF16904.5 EOO04456.1 - 0.12 12.6 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine synthase II C-terminus Zn-ribbon_8 PF09723.10 EOO04456.1 - 1.7 8.8 3.8 0.64 10.2 0.4 2.1 2 0 0 2 2 2 0 Zinc ribbon domain EPL1 PF10513.9 EOO04457.1 - 1.5e-34 119.7 0.6 1.1e-33 116.8 0.0 2.6 2 0 0 2 2 2 1 Enhancer of polycomb-like OPT PF03169.15 EOO04458.1 - 3.3e-37 128.4 5.1 4.2e-37 128.1 5.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DHFR_1 PF00186.19 EOO04460.1 - 4.2e-28 98.1 0.0 8.5e-28 97.1 0.0 1.6 1 1 0 1 1 1 1 Dihydrofolate reductase Ribosomal_L10 PF00466.20 EOO04461.1 - 1.3e-23 83.0 0.0 2e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 EOO04461.1 - 5.3e-21 74.4 0.0 8.1e-21 73.8 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P UPF0113 PF03657.13 EOO04462.1 - 4.6e-26 90.9 0.0 1.3e-25 89.4 0.0 1.7 2 0 0 2 2 2 1 UPF0113 PUA domain UPF0113_N PF17833.1 EOO04462.1 - 3.2e-24 85.3 0.0 4.4e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PUA PF01472.20 EOO04462.1 - 0.07 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 PUA domain ATP-synt_DE_N PF02823.16 EOO04463.1 - 3.7e-17 62.0 0.1 5.6e-17 61.4 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain WW PF00397.26 EOO04464.1 - 1e-07 31.9 2.5 3.3e-07 30.3 2.5 1.9 1 0 0 1 1 1 1 WW domain adh_short_C2 PF13561.6 EOO04465.1 - 7.6e-56 189.3 0.8 8.8e-56 189.1 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EOO04465.1 - 4.4e-47 160.1 0.2 5.7e-47 159.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EOO04465.1 - 1.1e-13 51.5 0.3 1.5e-13 51.1 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EOO04465.1 - 0.005 16.8 0.2 0.011 15.6 0.2 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EOO04465.1 - 0.035 13.5 0.1 0.4 10.1 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 EOO04465.1 - 0.099 13.1 0.1 0.51 10.8 0.1 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 EOO04465.1 - 0.14 12.0 0.2 1.3 8.9 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMN_dh PF01070.18 EOO04466.1 - 2.8e-45 154.8 0.0 3.2e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ApbA_C PF08546.11 EOO04467.1 - 7.6e-28 97.2 0.0 1.2e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EOO04467.1 - 6.1e-21 74.7 0.7 1.5e-14 53.9 0.0 2.2 1 1 1 2 2 2 2 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 EOO04467.1 - 0.1 11.9 1.2 0.25 10.6 1.0 1.7 2 0 0 2 2 2 0 ThiF family MFS_1 PF07690.16 EOO04468.1 - 1.1e-12 47.5 6.9 7e-12 44.9 5.7 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Phaeoacremonium_minimum_UCRPA7-UCRPA7V03/GCA_000392275.1_UCRPA7V03_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Phaeoacremonium_minimum_UCRPA7-UCRPA7V03/GCA_000392275.1_UCRPA7V03_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Phaeoacremonium_minimum_UCRPA7-UCRPA7V03/GCA_000392275.1_UCRPA7V03_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Phaeoacremonium_minimum_UCRPA7-UCRPA7V03/GCA_000392275.1_UCRPA7V03_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 02:51:41 2019 # [ok]